name: Factor IIa inhibitors (peptide) binds IIa (Mus musculus)


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Rattus norvegicus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Bos taurus)


name: Nephrin mediated activation of N-WASP (Sus scrofa)


name: betaine aldehyde hydrate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => choline + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine <=> 1-heptanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-heptanoyl-sn-glycero-3-phosphocholine


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Bos taurus)


name: NAGLU hydrolyses Heparan sulfate chain(4) (Drosophila melanogaster)


name: Closure of gap junction (Rattus norvegicus)


name: all-trans-4,4'-diapo-zeta-carotene + FADH2 => all-trans-4,4'-diapophytofluene + FAD + H(+)


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Schizosaccharomyces pombe)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: L-kynurenine + oxaloacetate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Sus scrofa)


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Drosophila melanogaster)


name: erythritol + NADP(+) = D-erythrose + H(+) + NADPH


name: DPPA3 binds histone H3K9me2 in chromatin (Homo sapiens)


name: 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + O2 <=> CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate


name: Dimeric TGF-beta-1 binds to the receptor (Homo sapiens)


name: acetyl-CoA + N-terminal L-methionyl-L-isoleucyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-isoleucyl-[protein]


name: glyoxylate + H2O + propanoyl-CoA <=> 3-methylmalate + CoA + H(+)


name: SPHK1 binds PKR (Caenorhabditis elegans)


name: Collagen type VII binds integrin alpha2beta1 (Xenopus tropicalis)


name: GDIs block activation of RHOG (Homo sapiens)


name: ATP + guanidinoethyl methyl phosphate => ADP + H(+) + N'-phosphoguanidinoethyl methylphosphate


name: [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + CoA => (9Z)-hexadecenoyl-CoA + [Wnt protein]-L-serine


name: Phosphorylation and activation of CHEK2 by ATM (Bos taurus)


name: oxidoreductase activity, acting on metal ions


name: ATP(in) + H2O(in) + Zn(2+)(out) => ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Plasmodium falciparum)


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Plasmodium falciparum)


name: formaldehyde + H2O + NAD(+) + xanthine => 7-methylxanthine + H(+) + NADH + O2


name: GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Bos taurus)


name: CoA + tetradecanyl tetradecanoate => tetradecan-1-ol + tetradecanoyl-CoA


name: Interaction of Tie2 and Grb14 (Rattus norvegicus)


name: 2-ethylhexyl sulfate + 2-oxoglutarate + O2 => 2-ethylhexanal + CO2 + H(+) + succinate + sulfate


name: 2-hydroxytetracosanoyl-CoA + sphinganine <=> CoA + H(+) + N-(2-hydroxytetracosanoyl)-sphinganine


name: acetoacetate + acetyl-CoA => acetate + acetoacetyl-CoA


name: VAV3 is a GEF for Rho/Rac family kinases (Canis familiaris)


name: 1-pyrroline-5-carboxylate + 2 H(+) + NADH => L-proline + NAD(+)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Rattus norvegicus)


name: Phosphorylation and activation of PLCG (Bos taurus)


name: 11-hydroxyferruginol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => carnosate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: ADP-D-ribose + H2O <=> AMP + D-ribose 5-phosphate + 2 H(+)


name: alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ (Danio rerio)


name: BPI binds LPS on the bacterial surface (Dictyostelium discoideum)


name: ATP + D-hamamelose <=> ADP + D-hamamelose 2'-phosphate + H(+)


name: HATs and coactivators are recruited to the CTSD gene (Xenopus tropicalis)


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate


name: 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) <=> CO2 + diphosphate + thiamine phosphate


name: acrolein + H2O + O2 = acrylate + H(+) + H2O2


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Mus musculus)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Caenorhabditis elegans)


name: Expression of OTX2 in anterior neural plate (Homo sapiens)


name: Growth hormone forms dimers and oligomers (Mus musculus)


name: 2-oxoglutarate + DIBOA beta-D-glucoside + O2 = CO2 + succinate + TRIBOA beta-D-glucoside


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Saccharomyces cerevisiae)


name: TP53 binds STK11 and NUAK1 (Mus musculus)


name: (R)-pantolactone + A = 2-dehydropantolactone + AH2


name: H2O + L-lysine + O2 => 6-amino-2-oxohexanoate + H2O2 + NH4(+)


name: 2'-hydroxy-2,3-dihydrodaidzein + NADP(+) = 2'-hydroxydaidzein + 2 H(+) + NADPH


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Sus scrofa)


name: petunidin + UDP-alpha-D-glucose <=> petunidin 3-O-beta-D-glucoside + UDP


name: (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[C-phycocyanin beta-subunit] => phycocyanobilin-L-cysteinyl(84)-[C-phycocyanin beta-subunit]


name: (S)-3-(imidazol-5-yl)lactate + NAD(+) = 3-(imidazol-5-yl)pyruvate + H(+) + NADH


name: Abortive termination of elongation after arrest (Drosophila melanogaster)


name: Histone acetyltransferases are recruited to the TFF1 gene (Rattus norvegicus)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH => 7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+)


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Homo sapiens)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Danio rerio)


name: 4-farnesyl-3,5-dihydroxy-6-methylphthalide + AH2 + 2 O2 => (4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + A + acetone + H(+) + H2O


name: ATP + citrate + CoA => (3S)-citryl-CoA + ADP + phosphate


name: 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-(9Z,12Z-octadecadienoyl)-glycerol + H(+)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Danio rerio)


name: ISGylation of DDX58 (Caenorhabditis elegans)


name: Iodide is taken up by thyroid epithelial cells (Caenorhabditis elegans)


name: Recruitment of VAV1 to p-6Y-SYK (Gallus gallus)


name: H2O + IMP + NAD(+) <=> H(+) + NADH + XMP


name: modified amino acid transmembrane transporter activity


name: 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH + O2 => 9alpha-hydroxy-3-oxochola-1,4-dien-22-oyl-CoA + H2O + NAD(+)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Xenopus tropicalis)


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Rattus norvegicus)


name: a quinone + sn-glycerol 3-phosphate => a quinol + dihydroxyacetone phosphate


name: a ubiquinol + nitrate => a ubiquinone + H2O + nitrite


name: 7,8-dihydroneopterin 3'-triphosphate <=> 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate


name: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH


name: IkB is ubiquitinated and degraded (Canis familiaris)


name: Interaction of DAP12 and KIR2DS1 (Rattus norvegicus)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Rattus norvegicus)


name: pyruvate dehydrogenase [NAD(P)+] activity


name: TOPORS SUMOylates SIN3A with SUMO1 (Gallus gallus)


name: Incorrectly folded glycoproteins translocate to the ERQC (Homo sapiens)


name: 2-aminoprop-2-enoate + 3-sulfanyl-1-hexanol => S-3-(hexan-1-ol)-L-cysteine


name: ARBB recruits GPCRs into clathrin-coated pits (Homo sapiens)


name: LPPG:FO 2-phospho-L-lactate transferase activity


name: TRAIL:TRAIL receptor trimers bind FADD (Rattus norvegicus)


name: 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + beta-D-Gal-(1<->1')-Cer


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine => 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: 3,3',5-triiodo-L-thyronine + A + H(+) + iodide = AH2 + L-thyroxine


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Sus scrofa)


name: butyrolactone II + dimethylallyl diphosphate = butyrolactone I + diphosphate


name: 17beta-estradiol + NAD(+) => estrone + H(+) + NADH


name: a medium chain fatty acid + ATP + CoA => a medium-chain fatty acyl-CoA + AMP + diphosphate


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Bos taurus)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Schizosaccharomyces pombe)


name: H(+) + NADPH + O2 + tetracycline => 11a-hydroxytetracycline + H2O + NADP(+)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O


name: CTNNB1 S45 mutants aren't phosphorylated by CK1alpha (Homo sapiens)


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Bos taurus)


name: Arachidonic acid is converted to HXA3/B3 by ALOX12 (Rattus norvegicus)


name: ADP + H(+) + Mg(2+)(in) + phosphate => ATP + H2O + Mg(2+)(out)


name: ADP + carbamoyl phosphate => ATP + carbamate


name: Autocatalytic phosphorylation of FGFR1b (Homo sapiens)


name: p-Y389,400-RUFY1 binds PI3P (Homo sapiens)


name: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoate => (E)-ferulate + H2O


name: Phosphorylated PKN1 binds androgen receptor (AR) (Homo sapiens)


name: PGRMC2:Hemes translocate to the nucleus (Bos taurus)


name: 2-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine => 2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine


name: 12-methyloctadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(13-methyl-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Canis familiaris)


name: O2 + pratensein + reduced [NADPH--hemoprotein reductase] <=> 5-hydroxypseudobaptigenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NCOA3 binds ESR1:estrogen:TFGA gene (Drosophila melanogaster)


name: Superoxide and nitric oxide react to peroxynitrite (Homo sapiens)


name: SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Xenopus tropicalis)


name: (R)-lactate + a quinone => a quinol + pyruvate


name: MITF-M dimer binds RAB27A gene (Homo sapiens)


name: 3,4-dihydroxyphenylacetate + 2 H(+) + NADH => 3,4-dihydroxyphenylacetaldehyde + H2O + NAD(+)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Danio rerio)


name: Recruitment of Rad17-RFC complex to DNA (Xenopus tropicalis)


name: Phosphorylation of SHC by SYK kinase (Mus musculus)


name: 16alpha-hydroxyprogesterone = 16,17-didehydroprogesterone + H2O


name: N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: DOLPP1 dephosphorylates DOLDP to DOLP (Sus scrofa)


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Rattus norvegicus)


name: GPETA is hydrolyzed to ETA and G3P by GPCPD1 (Homo sapiens)


name: 3-phosphoinositide-dependent protein kinase binding


name: H(+) + NADPH + nitrobenzene => H2O + NADP(+) + nitrosobenzene


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Sus scrofa)


name: Caspase 3-mediated cleavage of DFF45 (117) (Drosophila melanogaster)


name: albendazole + O2 + reduced [NADPH--hemoprotein reductase] => albendazole S-oxide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Bos taurus)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Rattus norvegicus)


name: 2-oxoglutarate + N(1)-methyladenosine(58) in tRNA + O2 <=> adenosine(58) in tRNA + CO2 + formaldehyde + succinate


name: Diacylgycerol activates Protein kinase C, alpha type (Rattus norvegicus)


name: RAC2 translocates to the phagocytic vesicle membrane (Bos taurus)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Gallus gallus)


name: a quinol + enol-oxaloacetate => (S)-malate + a quinone


name: MET phosphorylates SHC1-2 (Canis familiaris)


name: melanin-concentrating hormone receptor activity


name: (2E)-butenoyl-CoA + NH4(+) => (3S)-3-aminobutanoyl-CoA


name: lathosterol + NADP(+) = 5alpha-cholesta-7,24-dien-3beta-ol + H(+) + NADPH


name: ATP(in) + CoA(in) + H(+)(out) + hexadecanoate(out) <=> AMP(in) + diphosphate(in) + H(+)(in) + hexadecanoyl-CoA(in)


name: IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Homo sapiens)


name: (7R,8S)-7,8-diammoniononanoate + ATP + CO2 <=> (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate


name: RAC3 GAPs stimulate RAC3 GTPase activity (Homo sapiens)


name: D-xylulose 5-phosphate + sulfoacetaldehyde => 4-deoxy-4-sulfo-D-erythrulose + D-glyceraldehyde 3-phosphate


name: p-T68-CHEK2 autophosphorylates (Gallus gallus)


name: p85 regulatory unit of PI3K binds p-6Y-SYK (Canis familiaris)


name: PEX19:class I PMP binds PEX3 (Xenopus tropicalis)


name: Trans-homodimerization of Neurofascin (Homo sapiens)


name: ARBB recruits GPCRs into clathrin-coated pits (Bos taurus)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Schizosaccharomyces pombe)


name: H2O + N,1-diacyl-sn-glycero-3-phosphoethanolamine => a fatty acid + H(+) + N-acyl-sn-glycero-3-phosphoethanolamine


name: 2 Fe(III)-[cytochrome c553] + formate = CO2 + 2 Fe(II)-[cytochrome c553] + H(+)


name: "formate dehydrogenase (cytochrome c-553)"


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O <=> 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate


name: isoscopoletin + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + scoparone


name: Caspase-mediated cleavage of Acinus (Drosophila melanogaster)


name: (2E)-geranyl diphosphate => beta-phellandrene + diphosphate


name: glycyl-L-methionine + H2O => glycine + L-methionine


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Sus scrofa)


name: CSNK2-mediated phosphorylation of DVL (Caenorhabditis elegans)


name: acetyl-CoA + cyclohexanone => (1-hydroxycyclohexan-1-yl)acetyl-CoA


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Translocation of NuMA to the centrosomes (Bos taurus)


name: all-trans-retinyl hexadecanoate + H2O = H(+) + hexadecanoate + retinol


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Xenopus tropicalis)


name: 3-dehydro-alpha-D-glucosyl beta-D-fructofuranoside + H2O => 3-dehydro-D-glucose + D-fructose


name: GST trimers transfer GS from GSH to luminal substrates (Rattus norvegicus)


name: bPIX exchanges GTP for GDP on RAC, activating it (Homo sapiens)


name: Cross-linking of FCGRIIIA with IgG-coated Ag (Homo sapiens)


name: 3-dehydroquinate + a quinol => a quinone + L-quinate


name: (Z)-2-methylureidoacrylate + H2O <=> (Z)-2-methylaminoacrylate + carbamate + H(+)


name: (6R)-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) => 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH


name: (R)-lactate + ATP + D-alanine <=> ADP + D-alanyl-(R)-lactate + phosphate


name: 2'-deoxyuridine + NH4(+) => 2'-deoxycytidine + H(+) + H2O


name: indole + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase]


name: dimethyl sulfide + H(+) + NADH + O2 <=> dimethyl sulfoxide + H2O + NAD(+)


name: chlorophyll a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 7(1)-hydroxychlorophyll a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Danio rerio)


name: KCTD1 binds TFAP2 homo- and heterodimers (Mus musculus)


name: H2O + N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,2) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2)


name: H2O + L-glutamine + O2 => 2-oxoglutaramate + H2O2 + NH4(+)


name: a 5'-end NTP-ribonucleotide-RNA + H2O <=> a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + diphosphate + H(+)


name: ATP + H2O + xanthine(out) => ADP + H(+) + phosphate + xanthine(in)


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Dictyostelium discoideum)


name: estrone 3-sulfate(out) + pentanoate(in) <=> estrone 3-sulfate(in) + pentanoate(out)


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Saccharomyces cerevisiae)


name: p-FRS2:CRKL binds C3G (Xenopus tropicalis)


name: Autocatalytic phosphorylation of FGFR3c (Homo sapiens)


name: H(+)(in) + sarcosine(in) <=> H(+)(out) + sarcosine(out)


name: Association of procollagen type XXII (Gallus gallus)


name: 15-methylhexadecasphinganine 1-phosphate + ADP + H(+) => 15-methylhexadecasphinganine + ATP


name: 3-methylcatechol + NAD(+) + nitrite => 2-nitrotoluene + NADH + O2


name: luteolin + UDP-alpha-D-glucose = H(+) + isoorientin + UDP


name: (R)-carnitine + acetoacetyl-CoA = CoA + O-3-oxobutanoyl-(R)-carnitine


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Bos taurus)


name: Collagen type XV restin release (Sus scrofa)


name: jasmonyl-Ile conjugate hydrolase activity


name: PP2A demethylation by PPME1 (Xenopus tropicalis)


name: (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate => (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O


name: O2 + 4 tellimagrandin II => 2 cornusiin E + 2 H2O


name: NTPDase4 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)


name: IL12B translocates from the cytosol to the extracellular region (Xenopus tropicalis)


name: H2O + sphinga-4E,14Z-dienine-1-phosphate = phosphate + sphinga-4E,14Z-dienine


name: AH2 + 2 ATP + 2 cob(II)alamin = A + 2 adenosylcob(III)alamin + 2 H(+) + 2 triphosphate


name: PDE3A hydrolyses cAMP to AMP (Plasmodium falciparum)


name: (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + CO2 + CoA => (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + malonyl-CoA


name: aldehydo-D-ribose 5-phosphate <=> D-ribulose 5-phosphate


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Gallus gallus)


name: TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Homo sapiens)


name: (indol-3-yl)acetyl-AMP + CoA = (indol-3-yl)acetyl-CoA + AMP + H(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA + S-adenosyl-L-methionine


name: 10-oxooctadecanoate + H(+) + NADH = 10-hydroxyoctadecanoate + NAD(+)


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PHF8 demethylates MeK21-histone H4 (Rattus norvegicus)


name: a globoside MSGG (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a globoside DSGG (d18:1(4E)) + CMP + H(+)


name: MASTL (GWL) phosphorylates ARPP19 (Bos taurus)


name: 4-methylsulfanyl-2-oxobutanoate + L-tyrosine = 3-(4-hydroxyphenyl)pyruvate + L-methionine


name: L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[SCAN] <=> L-cysteinyl-[SCAN] + S-nitroso-L-cysteinyl-[protein]


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O => a 1-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Schizosaccharomyces pombe)


name: 4 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone => 4 Fe(II)-[cytochrome c] + 5 H(+) + L-dehydroascorbate


name: DHAP is converted to 1-acyl GO3P by GNPAT (Mus musculus)


name: H(+) + NADH + O2 + salicylate <=> 2,3-dihydroxybenzoate + H2O + NAD(+)


name: ULK3:SUFU dissociates (Canis familiaris)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Xenopus tropicalis)


name: acyl-lipid omega-3 desaturase (cytochrome b5) activity


name: n adenosine 3',5'-bisphosphate + dermatan 4'-sulfate + n H(+) => n 3'-phosphoadenylyl sulfate + dermatan


name: acetyl-CoA + 2 AH2 + 9 H(+) + malate + 6 malonyl-CoA + 5 NADPH + 2 S-adenosyl-L-methionine = 2 A + 6 CO2 + 7 CoA + 6 H2O + 5 NADP(+) + 2 S-adenosyl-L-homocysteine + trihazone A


name: FAM20C phosphorylates FAM20C substrates (Homo sapiens)


name: Beta-catenin translocates to the nucleus (Drosophila melanogaster)


name: NFE2L2-dependent PGD gene expression (Homo sapiens)


name: Interaction of particulate antigens with dendritic cell receptors (Bos taurus)


name: Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Homo sapiens)


name: ppDVL recruits RAC (Caenorhabditis elegans)


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Canis familiaris)


name: DENND6A,B exchange GTP for GDP on RAB14 (Dictyostelium discoideum)


name: CoA + H(+) + N-eicosanoyl-3-oxosphinganine => 3-oxosphinganine + eicosanoyl-CoA


name: EXO1 or DNA2 in complex with BLM or WRN binds initially resected DNA DSBs along with BRIP1 recruitment (Sus scrofa)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Drosophila melanogaster)


name: RIPK3 is cleaved by CASP8 (Homo sapiens)


name: HDACs deacetylate p-STAT3 dimers (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol = a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: Activated ATM phosphorylates ABL1 (Drosophila melanogaster)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine


name: BMX phosphorylates RUFY1 (Rattus norvegicus)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Mus musculus)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Bos taurus)


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Drosophila melanogaster)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII (Canis familiaris)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Xenopus tropicalis)


name: MMP2, MMP9 cleave SCUBE3 (Rattus norvegicus)


name: 2,5-didehydro-D-gluconate + H(+) + NADPH => 2-dehydro-D-gluconate + NADP(+)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Bos taurus)


name: ATP binding to HSP90 triggers conformation change (Drosophila melanogaster)


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Rattus norvegicus)


name: (+)-8'-hydroxyabscisate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-cis-(+)-abscisate + O2 + reduced [NADPH--hemoprotein reductase]


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-alpha-D-galactose <=> H(+) + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP


name: ethyl (R)-3-hydroxyhexanoate + NADP(+) <=> ethyl 3-oxohexanoate + H(+) + NADPH


name: G alpha (q) binds to Trio family RhoGEFs (Danio rerio)


name: (R)-lipoate(out) + 2 Na(+)(out) = (R)-lipoate(in) + 2 Na(+)(in)


name: Interaction of SHP-1 or SHP-2 with phospho PD-1 (Sus scrofa)


name: Activated ERKs phosphorylate ERF (Homo sapiens)


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Sus scrofa)


name: SDS dimers:PXLP dehydrate L-Thr to 2AA (Sus scrofa)


name: Cytosolic PLK1 translocates to the nucleus (Homo sapiens)


name: MTA is cleaved and phosphorylated (Danio rerio)


name: RHOG translocates to the ER membrane (Drosophila melanogaster)


name: 9-cis-retinyl ester + CoA => 9-cis-retinol + a fatty acyl-CoA


name: (4S)-perillyl alcohol + AH2 => (4S)-limonene + A + H2O


name: 3'-phosphoadenylyl sulfate + 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(beta-D-glucuronate) <=> 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: 5-methylcytosine + H(+) + H2O = NH4(+) + thymine


name: Cr(6+) + 2 NADPH + O2 => Cr(3+) + 2 H(+) + 2 NADP(+) + superoxide


name: O2 + reduced [NADPH--hemoprotein reductase] + taxusin = 2alpha-hydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-arginine(in) + L-lysine(out) = L-arginine(out) + L-lysine(in)


name: adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)


name: CD55 (DAF) binds C3bBb, C4bC2a (Bos taurus)


name: HMIT co-transports myo-inositol with a proton (Bos taurus)


name: VAV2 is a GEF for Rho/Rac family kinases (Canis familiaris)


name: 3-hydroxybenzoyl-CoA + AH2 + 2 ATP + 2 H2O <=> 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA + A + 2 ADP + 2 H(+) + 2 phosphate


name: Caspase-mediated cleavage of occludin (Rattus norvegicus)


name: "(R)-specific secondary-alkylsulfatase (type III)"


name: ADP + H(+) + phosphoenolpyruvate => ATP + pyruvate


name: a menaquinone + succinate => a menaquinol + fumarate


name: SEMA4A binds to PLXND1 (Drosophila melanogaster)


name: Direct recruitment of PI3K to p-KIT (Rattus norvegicus)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Xenopus tropicalis)


name: Formation of eEF1B complex (Schizosaccharomyces pombe)


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Canis familiaris)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Mus musculus)


name: ISL1 binds the SLIT2 gene enhancer (Homo sapiens)


name: (R)-S-lactoylglutathione + H2O <=> (R)-lactate + glutathione + H(+)


name: Caspase-8 and FLIP(L) processing at DISC (Sus scrofa)


name: TAK1 associated with the CBM complex phosphorylates IKKbeta (Homo sapiens)


name: 1-acyl LPC is acylated to PC by LPCAT (Xenopus tropicalis)


name: D-sorbitol + O2 <=> D-sorbopyranose + H2O2


name: acetyl-CoA + N-terminal L-methionyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[protein]


name: cytidine(49) in tRNA precursor + S-adenosyl-L-methionine <=> 5-methylcytidine(49) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: H(+) + H2O + urethane = CO2 + ethanol + NH4(+)


name: DENND4s exchange GTP for GDP on RAB10 (Homo sapiens)


name: ATP + D-alanine + holo-[D-alanyl-carrier protein] = AMP + D-alanyl-[D-alanyl-carrier protein] + diphosphate


name: Active calmodulin binds CAMK2 (Drosophila melanogaster)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)


name: H2O + UDP-alpha-D-glucuronate => 1-phospho-alpha-D-glucuronate + 2 H(+) + UMP


name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa (Bos taurus)


name: eicosanoyl-CoA + H2O <=> CoA + eicosanoate + H(+)


name: RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA (Sus scrofa)


name: 2 ATP + 2 H2O + 2 L-glutamine + Ni-sirohydrochlorin <=> 2 ADP + 2 H(+) + 2 L-glutamate + Ni-sirohydrochlorin a,c-diamide + 2 phosphate


name: H(+) + luteolin 7-O-beta-D-glucoside + UDP => luteolin + UDP-alpha-D-glucose


name: L-serine + tRNA(Lys) => H2O + L-seryl-tRNA(Lys)


name: delta-dodecalactone + H2O => 5-hydroxydodecanoate + H(+)


name: PDCD1 binds PDCD1 inhibitors (Homo sapiens)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane (Caenorhabditis elegans)


name: PPTN11 dephosphorylates SPRY2 (Canis familiaris)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Bos taurus)


name: Formation of RAD50:MRE11 complex (Gallus gallus)


name: all-trans-retinoate + UDP-alpha-D-glucuronate <=> all-trans-retinoyl-1-O-(beta-D-glucuronate) + UDP


name: SLC4A4 cotransports Na+ with 3HCO3- (Sus scrofa)


name: ATP + H2O + phosphinate(out) => ADP + H(+) + phosphate + phosphinate(in)


name: glycerol + H(+) + tetradecanoate => 1-tetradecanoylglycerol + H2O


name: ABCB1 transports PREDN,PREDL out of hepatic cells (Plasmodium falciparum)


name: 4alpha-hydroxymethylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Canis familiaris)


name: TRIM27 polyubiquitinates PTEN (Bos taurus)


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Caenorhabditis elegans)


name: (2,4-dichlorophenoxy)acetate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + CO2 + glyoxylate + succinate


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Dictyostelium discoideum)


name: 2 H(+) + 2 H2O + methylenediurea => CO2 + N-(hydroxymethyl)urea + 2 NH4(+)


name: 4,4'-disulfanyldibutanoate + H(+) + NADH => 2 4-sulfanylbutanoate + NAD(+)


name: butanoyl-CoA + ethanol <=> CoA + ethyl butanoate


name: PEX19 binds class I peroxisomal membrane proteins (Sus scrofa)


name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) (Canis familiaris)


name: H(+) + steviolmonoside + UDP => steviol + UDP-alpha-D-glucose


name: 3-(imidazol-5-yl)pyruvate + H(+) + NADH => (S)-3-(imidazol-5-yl)lactate + NAD(+)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Gallus gallus)


name: 4-hydroxy-N-methyltryptamine 4-phosphate + S-adenosyl-L-methionine <=> H(+) + psilocybin + S-adenosyl-L-homocysteine


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Xenopus tropicalis)


name: H2O + methyl (indol-3-yl)acetate <=> (indol-3-yl)acetate + H(+) + methanol


name: 2-[(3S)-3-carboxy-3-(methylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine => 2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-adenosyl-L-homocysteine


name: ATP + H2O + putrescine(out) => ADP + H(+) + phosphate + putrescine(in)


name: E2F7 forms homodimers (Rattus norvegicus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Rattus norvegicus)


name: FABP5:atRA translocates from cytosol to nucleoplasm (Sus scrofa)


name: H(+) + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + NADPH + O2 <=> 2 H2O + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADP(+)


name: NGEF exchanges GTP for GDP on RHOA (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate => diphosphate + germacrene A


name: CDK2:CCNA phosphorylates TERF2 (Rattus norvegicus)


name: HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Xenopus tropicalis)


name: 2-oxoglutarate(out) + dehydroepiandrosterone 3-sulfate(in) => 2-oxoglutarate(in) + dehydroepiandrosterone 3-sulfate(out)


name: PTENP1 mRNA binds miR-19b RISC (Homo sapiens)


name: PIAS4 SUMOylates TOP2A with SUMO2,3 (Bos taurus)


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Xenopus tropicalis)


name: ST3GAL5 transfers NeuNAc to ceramides (Mus musculus)


name: 1-O-alkyl-2-acyl-sn-glycerol + CDP-choline = 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: Joining of adjacent Okazaki fragments (Gallus gallus)


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Rattus norvegicus)


name: Phosphorylation of L1 by ERK (Canis familiaris)


name: Binding of TFIIIB to TFIIC: Type 2 Promoter Complex (Schizosaccharomyces pombe)


name: H2O + N-formylmethanofuran => formate + methanofuran


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + H(+) => 3,4-dihydroxybenzoyl-5'-AMP + holo-[aryl-carrier protein]


name: (2S)-2-hydroxynaringenin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase]


name: RISC binds inexactly matching target RNAs (Bos taurus)


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Caenorhabditis elegans)


name: 2-oxoglutaramate + L-phenylalanine => 3-phenylpyruvate + L-glutamine


name: CYP8B1 12-hydroxylates 4CHOL7aOLONE (Canis familiaris)


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Danio rerio)


name: ATP binding to HSP90 triggers conformation change (Canis familiaris)


name: NFE2L2 binds the IDH1 gene (Homo sapiens)


name: tandutinib-resistant FLT3 mutants don't bind tandutinib (Homo sapiens)


name: (9Z,12Z,15Z)-hexadecatrienoyl-CoA + A + 2 H2O => (9Z,12Z)-hexadecadienoyl-CoA + AH2 + O2


name: COQ4 decarboxylates MHDB (Drosophila melanogaster)


name: ATP + holo-[peptidyl-carrier protein] + L-proline => AMP + diphosphate + L-prolyl-[peptidyl-carrier protein]


name: 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol


name: Dimerization of p-S133-CREB1 (Homo sapiens)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Bos taurus)


name: Fe-coproporphyrin III + H(+) + H2O2 = CO2 + 2 H2O + harderoheme III


name: a nucleoside 5'-phosphate + H2O <=> a nucleoside + phosphate


name: histone H2B conserved C-terminal lysine deubiquitinase activity


name: Activation of Ca2+ activated Potassium channels with large conductance (Sus scrofa)


name: cortisone + H(+) + NADPH = 20beta-dihydrocortisone + NADP(+)


name: PP2A methylation by LCMT1 (Drosophila melanogaster)


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Gallus gallus)


name: CBL recruits CIN85:endophilin to ubiquitinated MET (Gallus gallus)


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Dictyostelium discoideum)


name: (R)-2-hydroxy-4-methylpentanoate + NAD(+) => 4-methyl-2-oxopentanoate + H(+) + NADH


name: TDG excises 5-formylcytosine (Mus musculus)


name: NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Canis familiaris)


name: Telomere shortening during replicative exhaustion (Bos taurus)


name: D-aspartyl-tRNA(Asp) + H2O <=> D-aspartate + H(+) + tRNA(Asp)


name: Fe(2+) + protoporphyrin IX => 2 H(+) + heme b


name: H2O + phloretin => 1,3,5-trihydroxybenzene + H(+) + phloretate


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine = H(+) + kanamycin X + UDP


name: H2O + methylglyoxal + NAD(+) = 2 H(+) + NADH + pyruvate


name: (2E)-decenoyl-[ACP] + H(+) + NADPH => decanoyl-[ACP] + NADP(+)


name: acetylation of serine (Mycobacterium tuberculosis)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Dictyostelium discoideum)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = H(+) + hexadecanoate + sn-glycerol 3-phosphocholine


name: (3Z)-dodecenoyl-CoA + acetyl-CoA => 3-oxo-(5Z-tetradecenoyl)-CoA + CoA


name: FA core complex:HSP70s binds PKR (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycerol + H(+) + phosphocholine


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Sus scrofa)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Caenorhabditis elegans)


name: HYKK phosphorylates 5HLYS (Mus musculus)


name: dehydroepiandrosterone 3-sulfate(out) + n H(+)(out) = dehydroepiandrosterone 3-sulfate(in) + n H(+)(in)


name: The p75NTR C-terminal fragment enters endosomes (Bos taurus)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Canis familiaris)


name: adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine


name: 1,2-dihexadecanoyl-sn-glycero-3-CDP + 1D-myo-inositol 3-phosphate = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)


name: TNF-alpha inhibitors bind to soluble TNF trimer (Xenopus tropicalis)


name: Autoproteolytic cleavage of Hh precursors (Bos taurus)


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Gallus gallus)


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Sus scrofa)


name: myricetin + S-adenosyl-L-methionine <=> H(+) + laricitrin + S-adenosyl-L-homocysteine


name: erythrodiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase]


name: 2 H2O + 2 indole-5,6-quinone-2-carboxylate => 2 5,6-dihydroxyindole-2-carboxylate + O2


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Mus musculus)


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Homo sapiens)


name: 2-aminoisobutanoate(in) + L-alanine(out) => 2-aminoisobutanoate(out) + L-alanine(in)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Gallus gallus)


name: propanoyl-CoA + tetradecanoyl-CoA <=> 3-oxo-2-methylhexadecanoyl-CoA + CoA


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Dictyostelium discoideum)


name: PAN2-PAN3 complex partially deadenylates mRNA (Saccharomyces cerevisiae)


name: SRD5A3 dehydrogenates TEST to DHTEST (Caenorhabditis elegans)


name: ZNRF3 autoubiquitinates to promote its internalization (Mus musculus)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Gallus gallus)


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Danio rerio)


name: Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Mus musculus)


name: glutamine + H2O => glutamate + NH4+ [GLS] (Xenopus tropicalis)


name: 3-methyl-2-oxobutanoate(in) + H(+)(in) => 3-methyl-2-oxobutanoate(out) + H(+)(out)


name: 4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + H(+) + S-adenosyl-L-homocysteine


name: cytidine(50) in tRNA + S-adenosyl-L-methionine = 5-methylcytidine(50) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: (4-hydroxyphenyl)acetaldehyde + H2O + NAD(+) = 4-hydroxyphenylacetate + 2 H(+) + NADH


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + choline + H(+) => 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O


name: ADRM1 binds 26S proteasome (Drosophila melanogaster)


name: CO2 + demethylphylloquinone + diphosphate => 1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate


name: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 <=> 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)


name: Delta(1)-dihydrotestosterone + H2O = 1,17beta-dihydroxyandrostan-3-one


name: IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Sus scrofa)


name: PE is methylated to PC by PEMT (Homo sapiens)


name: alpha-D-galactose + ATP => ADP + alpha-D-galactose 1-phosphate + H(+)


name: a menaquinone + 2 H(+) + hydrogen sulfide + sulfite = a menaquinol + thiosulfate


name: CBL ubiquitinates FRS2 and FGFR3 (Drosophila melanogaster)


name: Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide <=> Ni(2+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: STAT1,STAT3,STAT6 phosphorylation (Sus scrofa)


name: p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-dodecanoylglycerol = 1-dodecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: PGH2 is isomerised to PGD2 by HPGDS (Canis familiaris)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH => cholate + NADP(+)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Canis familiaris)


name: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CDSN binds the cornified envelope (Bos taurus)


name: MET phosphorylates STAT3 (Rattus norvegicus)


name: hepatocyte growth factor receptor binding


name: chenodeoxycholoyl-CoA + taurine => CoA + H(+) + taurochenodeoxycholate


name: 2'-deamino-2'-hydroxyneamine + UDP-alpha-D-glucose => H(+) + kanamycin D + UDP


name: Ubiquitinated Orc1 enters the cytosol (Drosophila melanogaster)


name: H2O + N-(9Z-hexadecenoyl) ethanolamine <=> (9Z)-hexadecenoate + ethanolamine


name: GOT2 dimer deaminates L-Asp (Danio rerio)


name: Formation of the MLL4 complex (Homo sapiens)


name: 26Sproteasome degrades K48polyUb-NIK (Saccharomyces cerevisiae)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Caenorhabditis elegans)


name: germacra-1(10),4,11(13)-trien-12-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => germacra-1(10),4,11(13)-trien-12-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: cadaverine + S-adenosyl 3-(methylsulfanyl)propylamine = aminopropylcadaverine + H(+) + S-methyl-5'-thioadenosine


name: Expression of Aryl Hydrocarbon receptor-interacting protein (Homo sapiens)


name: I(1,3,4)P3 is dephosphorylated to I(1,3)P2 by INPP4A/B in the cytosol (Sus scrofa)


name: NOTCH4 binds FLT4 gene promoter (Homo sapiens)


name: D-ribitol 1-phosphate + H2O <=> phosphate + ribitol


name: RELN:VLDLR:DAB1 binds SH3KBP1 (Sus scrofa)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Caenorhabditis elegans)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Gallus gallus)


name: eicosanoyl-CoA + glycine <=> CoA + H(+) + N-eicosanoylglycinate


name: 3-oxochol-4-en-22-oyl-CoA + A = 3-oxochola-4,17-dien-22-oyl-CoA + AH2


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Rattus norvegicus)


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Bos taurus)


name: G or G analog binds C-ter TLR7 dimer (Canis familiaris)


name: USP30 deubiquitinates Ub-MOM proteins (Xenopus tropicalis)


name: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> a 1-acyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: carbamoyl phosphate + ornithine => citrulline + orthophosphate (Xenopus tropicalis)


name: 2 glutathione + H2O2 <=> glutathione disulfide + 2 H2O


name: DKK and KRM bind LRP5/6 (Rattus norvegicus)


name: CO2 + N(6)-[(R)-S(8)-glutaryldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] => 2-oxoadipate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase]


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Canis familiaris)


name: (-)-minovincinine + acetyl-CoA = (-)-echitovenine + CoA


name: The keratan chain can be capped by N-acetylneuraminic acid (Danio rerio)


name: ATP + coproporphyrin I(in) + H2O <=> ADP + coproporphyrin I(out) + H(+) + phosphate


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA1 (d18:1(4E)/18:0) = CMP + ganglioside GM1 (d18:1(4E)/18:0) + H(+)


name: Formation of collagen fibrils (Sus scrofa)


name: Dopamine translocates to a secretory vesicle (Homo sapiens)


name: SLC35B2,3 transport cytosolic PAPS to Golgi lumen (Drosophila melanogaster)


name: Recruitment of Spike trimer to assembling virion (Homo sapiens)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Xenopus tropicalis)


name: 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH


name: Formation of peptide loading complex (PLC) (Mus musculus)


name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Drosophila melanogaster)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Homo sapiens)


name: HOXB1 gene is transcribed (Homo sapiens)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ATP + L-glutamate = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + H(+) + phosphate


name: ESR1-dependent CCND1 expression (Homo sapiens)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cholate + L-phenylalanine => H2O + L-phenylalanocholate


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)


name: D-dopa + H2O + O2 <=> 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: Electron transfer from reduced cytochrome c to molecular oxygen (Homo sapiens)


name: (R)-carnitine + an acyl-CoA = CoA + O-acyl-(R)-carnitine


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Bos taurus)


name: Alkalization of the phagosomal lumen by NOX2 (Danio rerio)


name: UMPS dimer decarboxylates OMP to UMP (Drosophila melanogaster)


name: a phenol + an aryl sulfate <=> a phenol + an aryl sulfate


name: ESR1:ESTG bind the EBAG9 5' region (Homo sapiens)


name: pyruvate dehydrogenase (quinone) activity


name: H(+)(in) + sucrose(out) = H(+)(out) + sucrose(in)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Homo sapiens)


name: A + H2O + quinolin-8-ol = 8-hydroxyquinolin-2(1H)-one + AH2


name: NOTCH1 Coactivator Complex binds HES1 promoter (Homo sapiens)


name: BTG2 binds CCR4-NOT complex (Rattus norvegicus)


name: 3-methoxyphenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] => Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + veratrole


name: H2O + NADP(+) => ADP-D-ribose 2'-phosphate + H(+) + nicotinamide


name: p-Y705,S727 STAT3 is acetylated (Mus musculus)


name: UBXN1 binds BRCA1:BARD1 heterodimer (Canis familiaris)


name: ATP + glutathione(in) + glycochenodeoxycholate(in) + H2O = ADP + glutathione(out) + glycochenodeoxycholate(out) + H(+) + phosphate


name: EDNRA binds selective ERAs (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphocholine = 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: L-Glutamate binds GRM4 (mGluR4) (Homo sapiens)


name: MMP2,9 cleave EPHB (Caenorhabditis elegans)


name: 3-hydroxy-L-kynurenine + H2O => 3-hydroxyanthranilate + H(+) + L-alanine


name: Li(+)(in) + melibiose(in) <=> Li(+)(out) + melibiose(out)


name: 3-dehydro-6alpha-hydroxy-28-norteasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6-dehydro-28-norteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Activation of HCN channels (Rattus norvegicus)


name: RHOA binds effectors at the plasma membrane (Caenorhabditis elegans)


name: 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (1S)-1,25-dihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin]


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Sus scrofa)


name: CO2 + hydroxymethylphosphonate + succinate => 2-oxoglutarate + methylphosphonate + O2


name: NADP(+) + pyridine 3-methanol = H(+) + NADPH + pyridine-3-carbaldehyde


name: Thrombin-activated PARs activate G12/13 (Homo sapiens)


name: Depolymerization of lamin filaments after PKC-mediated phosphorylation (Rattus norvegicus)


name: NAD(+) + propane-1,3-diol => 3-hydroxypropanal + H(+) + NADH


name: PGLYRP2 binds bacterial peptidoglycan (Gallus gallus)


name: NEIL1 cleaves DHU from damaged DNA (Gallus gallus)


name: 1D-myo-inositol 1,4-bisphosphate + phosphate => 1D-myo-inositol 1,4,5-trisphosphate + H2O


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Caenorhabditis elegans)


name: aculene D + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase] => asperaculane G + O2 + reduced [NADPH--hemoprotein reductase]


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Xenopus tropicalis)


name: Beclin-1 complex phosphorylates PtdIns (Canis familiaris)


name: Activation of Rac1 by pVav1 (Rattus norvegicus)


name: a ganglioside GD1a + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GD1a + H(+) + UDP


name: TBC1D14 binds RAB11 and ULK1 (Rattus norvegicus)


name: a 2-iminocarboxylate + H2O2 => a D-alpha-amino acid + O2


name: H(+) + N-octadecanoylsphing-4-enine + phosphocholine => H2O + N-(octadecanoyl)-sphing-4-enine-1-phosphocholine


name: Rheb in the MTORC1 complex hydrolyses GTP (Homo sapiens)


name: SLC6A18 transports Gly from extracellular region to cytosol (Homo sapiens)


name: HV1-mediated H+ transfer (Gallus gallus)


name: H2O + pyrrole-2-carboxylate <=> 1H-pyrrole + hydrogencarbonate


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(34-hydroxytetratriacontadienoyl)-sphing-4-enine = a diacylglycerol + an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontadienoyl)-sphing-4-enine


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Homo sapiens)


name: SORD tetramer oxidizes xylitol to D-xylulose (Schizosaccharomyces pombe)


name: 3alpha-sulfodeoxycholate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + deoxycholate


name: losartan-1-N-beta-D-glucuronide + UDP => losartan + UDP-alpha-D-glucuronate


name: AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + ethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + L-serine


name: 2-oxoglutarate + L-aspartyl-[protein] + O2 => (3S)-3-hydroxy-L-aspartyl-[protein] + CO2 + succinate


name: H(+) + NADH + pyruvate + taurine => H2O + NAD(+) + tauropine


name: LCNs bind lipids (Drosophila melanogaster)


name: alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NSF and SNAPs bind cis-SNARE complex (Sus scrofa)


name: H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine <=> (R)-4'-phosphopantetheine + CO2


name: H(+) + nonanoyl-CoA + oxidized [electron-transfer flavoprotein] <=> (2E)-nonenoyl-CoA + reduced [electron-transfer flavoprotein]


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Caenorhabditis elegans)


name: Binding of the MCC complex to the APC/C complex (Homo sapiens)


name: factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Bos taurus)


name: (1S,4S)-camphor + H(+) + NADH => (1S,2R,4S)-borneol + NAD(+)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Mus musculus)


name: ATP + H2O + Mg(2+) + protoporphyrin IX => ADP + 3 H(+) + Mg-protoporphyrin IX + phosphate


name: glutarate + succinyl-CoA = glutaryl-CoA + succinate


name: a dicarboxylate(in) + prostaglandin F2alpha(out) => a dicarboxylate(out) + prostaglandin F2alpha(in)


name: 11-O-acetylcyathatriol + UDP-alpha-D-xylose = erinacine Q + H(+) + UDP


name: 4-methylphenol + H2O + 2 oxidized [azurin] <=> 4-hydroxybenzyl alcohol + 2 H(+) + 2 reduced [azurin]


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(in) + ATP + H2O <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(out) + ADP + H(+) + phosphate


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+) => 1-O-hexadecyl-2-acetyl-sn-glycerol + ATP


name: cortisone + H(+) + NADPH => 20beta-dihydrocortisone + NADP(+)


name: IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor (Homo sapiens)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Danio rerio)


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A => 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: SHC1 phosphorylation by phosphorylated EGFR (Canis familiaris)


name: EHMT1:EHMT2 methylates IL6 promoter (Bos taurus)


name: Glucosylation of collagen propeptide hydroxylysines (Caenorhabditis elegans)


name: CDK5 phosphorylates DARPP-32 on Thr75 (Rattus norvegicus)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Saccharomyces cerevisiae)


name: Activated IKK phosphorylates I-kappaB (Canis familiaris)


name: Endophilins recruit synaptojanins to the clathrin-coated pit (Sus scrofa)


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Homo sapiens)


name: DHTKD1 dimer decarboxylates 2-OA (Canis familiaris)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Plasmodium falciparum)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 19-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cholesterol + PAPS => cholesterol sulfate + PAP (Mus musculus)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: WLS is endocytosed to the early endosome (Rattus norvegicus)


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Homo sapiens)


name: (Z)-3-ureidoacrylate + H2O <=> (Z)-3-aminoacrylate + carbamate + H(+)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: 3-methyl-(2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] => 3-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: RhBG mediates ammonium influx into kidney collecting duct cells (Rattus norvegicus)


name: isorhamnetin + S-adenosyl-L-methionine = 3',4'-O-dimethylquercetin + 2 H(+) + S-adenosyl-L-homocysteine


name: [(1->4)-beta-D-mannuronosyl](n) + GDP-alpha-D-mannuronate => [(1->4)-beta-D-mannuronosyl](n+1) + GDP + H(+)


name: Active ALK phosphorylates PLCG1 (Mus musculus)


name: Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine <=> 3,8-divinyl protochlorophyllide a + 5'-deoxyadenosine + 2 H(+) + L-methionine


name: B4GALTs transfer Gal to a branch of keratan (Sus scrofa)


name: HMOX1 dimer, HMOX2 cleave heme (Drosophila melanogaster)


name: 2,6-dichlorohydroquinone + chloride + glutathione disulfide + H(+) = 2,3,6-trichlorohydroquinone + 2 glutathione


name: acetaldehyde + chemical entity + H(+) + nitrite => ethylnitronate + O2


name: Homodimerization of VEGF proteins (Canis familiaris)


name: 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O => (9Z)-octadecenoate + 2-(9Z,12Z-octadecadienoyl)-glycerol + H(+)


name: A + glutaryl-CoA => (2E)-glutaconyl-CoA + AH2


name: SUMOylation of TOPORS with SUMO1 (Mus musculus)


name: 2-(2-methylsulfanyl)ethylmalate + CoA + H(+) => 4-methylsulfanyl-2-oxobutanoate + acetyl-CoA + H2O


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Danio rerio)


name: hydrolase activity, acting on glycosyl bonds


name: HEY1 gene expression is stimulated by NOTCH4 (Homo sapiens)


name: 5-hydroxymethyl-dUMP in DNA + ATP = 5-phosphomethyl-dUMP in DNA + ADP + H(+)


name: PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Gallus gallus)


name: [protein]-L-glutamate 5-O-methyl ester + H2O <=> H(+) + L-glutamyl-[protein] + methanol


name: KCNK dimers transport K+ from cytosol to extracellular region (Drosophila melanogaster)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Saccharomyces cerevisiae)


name: a ganglioside GD1b + H2O = a ganglioside GM1 + N-acetylneuraminate


name: H(+) + NADP(+) + 2 reduced [4Fe-4S]-[ferredoxin] = NADPH + 2 oxidized [4Fe-4S]-[ferredoxin]


name: OPTN binds TBK1 within the activated TLR3 complex (Homo sapiens)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: SUMOylation of Histone H4 with SUMO3 (Gallus gallus)


name: Activated FGFR1 binds FLRT1,2,3 (Danio rerio)


name: H2O + pyrrole-2-carboxylate = 1H-pyrrole + hydrogencarbonate


name: prekallikrein + kininogen:C1q binding protein tetramer -> prekallikrein:kininogen:C1q binding protein tetramer (Xenopus tropicalis)


name: D-glyceraldehyde 3-phosphate + NADP(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADPH


name: (R)-carnitine + 3-hydroxybutanoyl-CoA = CoA + O-3-hydroxybutanoyl-(R)-carnitine


name: a secondary alcohol + NADP(+) = a ketone + H(+) + NADPH


name: a 1,3-diacylglycerol + an acyl-CoA = a triacylglycerol + CoA


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Bos taurus)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Canis familiaris)


name: CDC42 GDIs block activation of CDC42 (Mus musculus)


name: 2-oxoglutarate + chrodrimanin H + O2 => chrodrimanin E + CO2 + H2O + succinate


name: Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Xenopus tropicalis)


name: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O


name: acetyl-CoA + L-tryptophan + malonyl-CoA = CO2 + 2 CoA + cyclo-acetoacetyl-L-tryptophan + H2O


name: RNF146 binds RibC-AXIN:TNKS complex (Homo sapiens)


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate


name: 4-O-(beta-D-glucosyl)-(E)-coniferol + H2O = (E)-coniferol + D-glucose


name: (25R)-cholest-5-en-3beta,7alpha,26-triol + NAD(+) = (25R)-7alpha,26-dihydroxycholest-4-en-3-one + H(+) + NADH


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Caenorhabditis elegans)


name: 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+) => 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Xenopus tropicalis)


name: sphinganine + tetracosenoyl-CoA => an N-tetracosenoylsphinganine + CoA + H(+)


name: Gbeta:gamma recruits PI3K gamma (Homo sapiens)


name: 2 H2O + L-cystine-bis-glycine = 2 glycine + L-cystine


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Danio rerio)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+) <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: 17beta-estradiol 3-sulfate(out) + 2 Na(+)(out) <=> 17beta-estradiol 3-sulfate(in) + 2 Na(+)(in)


name: PINK1 phosphorylates PRKN at S65 (Homo sapiens)


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Sus scrofa)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Dictyostelium discoideum)


name: cyclohexan-1,2-dione + H2O => 6-oxohexanoate + H(+)


name: UROD decarboxylates URO1 to COPRO1 (Saccharomyces cerevisiae)


name: UV-DDB ubiquitinates XPC (Xenopus tropicalis)


name: RHOH binds GTP (Dictyostelium discoideum)


name: p-6Y-SYK phosphorylates BLNK (SLP65) (Sus scrofa)


name: (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl) ethanolamine + H2O = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ethanolamine


name: NAD(+) <=> 2'cADPR + H(+) + nicotinamide


name: CYP11A1 cleaves 20a,22b-DHCHOL (Homo sapiens)


name: isobutanol + NAD(+) = 2-methylpropanal + H(+) + NADH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O = adenosine 3',5'-bisphosphate + 2 H(+) + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Schizosaccharomyces pombe)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Gallus gallus)


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) <=> [thioredoxin]-dithiol + glycine + H(+) + phosphate


name: RNA lariat debranching enzyme activator activity


name: 1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-O-octadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Canis familiaris)


name: ALKBH2 binds alkylated dsDNA containing 3-meC (Homo sapiens)


name: Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA (Drosophila melanogaster)


name: L-glutamine(in) + L-methionine(out) + Na(+)(out) <=> L-glutamine(out) + L-methionine(in) + Na(+)(in)


name: SLC26A5 (prestin) changes conformation in response to depolarization (Homo sapiens)


name: Netrin-4 binds DCC/UNC5A (Rattus norvegicus)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Sus scrofa)


name: 11-cis-retinoate + 2 H(+) + NADH => 11-cis-retinal + H2O + NAD(+)


name: H(+)(out) + L-alanyl-L-prolylglycine(out) = H(+)(in) + L-alanyl-L-prolylglycine(in)


name: carminate + O2 = 3'-dehydrocarminate + H2O2


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Dictyostelium discoideum)


name: SARS-CoV-2 9b binds IKBKG (Homo sapiens)


name: 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Homo sapiens)


name: 3-oxooctanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxyoctanoyl-[ACP] + NADP(+)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NFKB1:RELA translocates from the cytosol to the nucleus (Homo sapiens)


name: p38 MAPK phosphorylates PPARGC1A (Homo sapiens)


name: B-RAF dissociates from S111/S120 p-SPRY2 (Canis familiaris)


name: 2 H(+)(out) + menaquinol-8 => 2 H(+)(in) + H2 + menaquinone-8


name: H2O + limonin + UDP-alpha-D-glucose => glucosyl-limonin + 2 H(+) + UDP


name: Translocation of ISGF3 complex to nucleus (Sus scrofa)


name: Neurofascin interacts with syntenin-1 (Canis familiaris)


name: TGFBR2 recruits TGFBR1 (Canis familiaris)


name: eNoSC deacetylates histone H3 (Saccharomyces cerevisiae)


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Homo sapiens)


name: ATP-dependent chromatin remodeler activity


name: SCNN channels transport extracellular Na+ to cytosol (Caenorhabditis elegans)


name: PREX2 binds PTEN and inhibits it (Rattus norvegicus)


name: Direct recruitment of PI3K to p-KIT (Mus musculus)


name: Transcription of canonical WNT targets is negatively regulated by NLK-dependent phosphorylation of TCF/LEF (Homo sapiens)


name: Activated FGFR3 binds SHC1 (Drosophila melanogaster)


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Rattus norvegicus)


name: (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + H(+) + NADPH + O2 => H2O + NADP(+) + semiviriditoxin


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Canis familiaris)


name: biliverdin IXalpha + reduced coenzyme F420-(gamma-L-Glu)(n) => (4Z,15Z)-bilirubin IXalpha + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: Activated PKC-alpha  activate MMP3 (Canis familiaris)


name: Interaction of SIGLEC14/15/16 and DAP12 (Sus scrofa)


name: (3R)-hydroxyhexacosanoyl-CoA = (2E)-hexacosenoyl-CoA + H2O


name: IL1F10(?-152) binds IL1RAPL1 (Xenopus tropicalis)


name: EDNRA binds selective ERAs (Gallus gallus)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Gallus gallus)


name: D-maltotetraose + H2O <=> alpha-D-glucose + D-maltotriose


name: N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Plasmodium falciparum)


name: PDGF binds to extracellular matrix proteins (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 <=> (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Drosophila melanogaster)


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: MDM2 ubiquitinates DYRK2 (Gallus gallus)


name: BRAP autoubiquitinates (Rattus norvegicus)


name: (2R,4S)-ketoconazole(in) + ATP + H2O <=> (2R,4S)-ketoconazole(out) + ADP + H(+) + phosphate


name: a globoside NOR1 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside NORint (d18:1(4E)) + H(+) + UDP


name: 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 8,12-diethyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: (R)-4'-phosphopantetheine + ATP + H(+) <=> 3'-dephospho-CoA + diphosphate


name: "With a iron-sulfur protein as acceptor"


name: decanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 10-hydroxydecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IRAK2 induces TRAF6 oligomerization (Canis familiaris)


name: 2xTPK1:Mg2+ phosphorylates THMN (Drosophila melanogaster)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Homo sapiens)


name: MAPK6 is degraded by the 26S proteasome (Homo sapiens)


name: SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 (Homo sapiens)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Mus musculus)


name: RHOQ GEFs activate RHOQ (Dictyostelium discoideum)


name: ADP + H(+) + O-(L-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein] => ADP-L-glycero-beta-D-manno-heptose + L-seryl-[protein]


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Sus scrofa)


name: CoA + H(+) + N-tetracosanoyl-taurine => taurine + tetracosanoyl-CoA


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Caenorhabditis elegans)


name: succinate(in) + urate(out) => succinate(out) + urate(in)


name: histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen (Gallus gallus)


name: Formation of the pre-incision complex in GG-NER (Gallus gallus)


name: (9Z,12Z)-octadecadienoate + glycerol + H(+) => 2-(9Z,12Z-octadecadienoyl)-glycerol + H2O


name: 2 Fe(III)-[leghemoglobin] + NADH = 2 Fe(II)-[leghemoglobin] + H(+) + NAD(+)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Rattus norvegicus)


name: ATP + glycyl-[methyl-coenzyme M reductase] + hydrogen sulfide = ADP + phosphate + thioglycyl-[methyl-coenzyme M reductase]


name: carnosine + H2O = beta-alanine + L-histidine


name: SULTs transfer (SO4)2- group to 27HCHOL (Rattus norvegicus)


name: Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 (Mus musculus)


name: p107 (RBL1) binds CyclinE/A:CDK2 (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + an acyl-CoA


name: ADP + H(+) + keto-D-tagatose 6-phosphate => ATP + keto-D-tagatose


name: structural constituent of pupal chitin-based cuticle


name: PAK binds RAC and bPIX (Drosophila melanogaster)


name: H2O + N-acetylputrescine + O2 <=> 4-acetamidobutanal + H2O2 + NH4(+)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Xenopus tropicalis)


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Schizosaccharomyces pombe)


name: Active FLT3 binds to CSK (Canis familiaris)


name: Defective IDS does not hydrolyse Heparan sulfate chain(5) (Homo sapiens)


name: Endosome acidification (Rattus norvegicus)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Mus musculus)


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Canis familiaris)


name: RHOB binds effectors at the plasma membrane (Drosophila melanogaster)


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Xenopus tropicalis)


name: POLZ elongates POLI-incorporated dNMP (Gallus gallus)


name: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Homo sapiens)


name: Autoglucosylation of GYG2 complexed with GYS2-b (Homo sapiens)


name: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) <=> 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: MFSD2A transports LPC from extracellular region to plasma membrane (Sus scrofa)


name: GTSE1 translocates to the nucleus (Mus musculus)


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Drosophila melanogaster)


name: Monoubiquitinated PTEN translocates to the nucleus (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: castasterone + O2 + reduced [NADPH--hemoprotein reductase] => brassinolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Gallus gallus)


name: Collagen type VII dimerization (Caenorhabditis elegans)


name: VENTX binds the IL6 gene promoter (Homo sapiens)


name: p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor (Mus musculus)


name: RDH5 oxidises 11cROL to 11cRAL (Bos taurus)


name: acetate + ATP + CoA => acetyl-CoA + AMP + diphosphate


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2A (GRIN2A) (Homo sapiens)


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)


name: ROK binds to activated RHO1:GTP (Drosophila melanogaster)


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Homo sapiens)


name: GEFs activate RhoA,B,C (Caenorhabditis elegans)


name: N-(9Z-octadecenoyl)-(2S)-hydroxyglycine => (9Z)-octadecenamide + glyoxylate


name: (S)-reticuline + S-adenosyl-L-methionine = (S)-laudanine + H(+) + S-adenosyl-L-homocysteine


name: 2 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol <=> 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a cardiolipin


name: hydrogen cyanide + pentanal = (2S)-2-hydroxyhexanenitrile


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)


name: 1D-myo-inositol hexakisphosphate + ATP = 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP


name: (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADPH = H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NADP(+)


name: 5-N(alpha)-glycyl-dTMP in DNA + AH2 + S-adenosyl-L-methionine => 5'-deoxyadenosine + 5-C(alpha)-glycyl-dTMP in DNA + A + H(+) + L-methionine


name: CTP + N,N-diacetyllegionaminate => CMP-N,N-diacetyllegionaminate + diphosphate


name: JAK3 binds JAK3 inhibitors (Xenopus tropicalis)


name: neurotransmitter transmembrane transporter activity


name: P2RY12 binds P2RY12 antagonists (Danio rerio)


name: Hydrolysis of PC to PA by PLD (Saccharomyces cerevisiae)


name: (S)-carnitine + ATP + CoA <=> (S)-carnitinyl-CoA + ADP + phosphate


name: (E)-oct-2-en-1-ol + NADP(+) = (2E)-octenal + H(+) + NADPH


name: C1-Inh binds and inactivates C1r, C1s (Rattus norvegicus)


name: Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 (Homo sapiens)


name: 2-methylpentanoate + ATP + CoA => 2-methylpentanoyl-CoA + AMP + diphosphate


name: 4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 => 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Gallus gallus)


name: 2 (S)-lactate(in) + thromboxane B2(out) <=> 2 (S)-lactate(out) + thromboxane B2(in)


name: Formation of MSH2:MSH3 Complex (Gallus gallus)


name: BIRC(cIAP1/2) ubiquitinates RIPK1 (Gallus gallus)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Homo sapiens)


name: ACP6 hydrolyses MYS-LPA (Dictyostelium discoideum)


name: Loading of claspin onto DNA during replication origin firing (Schizosaccharomyces pombe)


name: CEBPB gene transcription is enhanced by phospho-CREB1 and phospho-STAT3 (Homo sapiens)


name: DPH6 ligates ammonium to diphthine-EEF2 (Rattus norvegicus)


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)


name: Dopa is decarboxylated to dopamine (Homo sapiens)


name: AFG3L2 binds mitochondrial inner membrane proteins (Drosophila melanogaster)


name: catechol + H(+) + NADPH => (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+)


name: H2O + N-(15Z-tetracosenoyl)-sphing-4-enine => (15Z)-tetracosenoate + sphing-4-enine


name: N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = H(+) + N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + UDP


name: p-Y701-STAT1 dimerizes (Dictyostelium discoideum)


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Canis familiaris)


name: ADRB2 bind ADR,NAd (Drosophila melanogaster)


name: (9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + UDP-alpha-D-glucose = (9Z)-17-hydroxyoctadec-9-enoate 17-O-sophoroside + H(+) + UDP


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Xenopus tropicalis)


name: Surface deployment of platelet dense granule membrane components (Mus musculus)


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Homo sapiens)


name: H2O + L-methionyl-tRNA(Leu) <=> H(+) + L-methionine + tRNA(Leu)


name: PAK1-3 dimer disassociates (Rattus norvegicus)


name: BHLHE22 recruits PRDM8 to intron 1 of CDH11 gene (Homo sapiens)


name: STAT3 binds activated MET receptor (Canis familiaris)


name: L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Rattus norvegicus)


name: L-serine + NADP(+) => aminoacetaldehyde + CO2 + NADPH


name: PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Bos taurus)


name: Elastin degradation by MMP14 (Homo sapiens)


name: HGD dioxygenates homogentisate (Danio rerio)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Sus scrofa)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Xenopus tropicalis)


name: a 1-acylglycerol + H2O <=> a fatty acid + glycerol + H(+)


name: (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O => (9Z,12Z)-octadecadienoate + AH2 + O2


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Rattus norvegicus)


name: RNF8 and RNF168 ubiquitinate H2AFX (Gallus gallus)


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Danio rerio)


name: adenosine 5'-tetraphosphate + AMP + 2 H(+) => H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate


name: Phosphorylation of MEF2 proteins by p38 (Xenopus tropicalis)


name: 2 Na(+)(in) + tauro-beta-muricholate(in) => 2 Na(+)(out) + tauro-beta-muricholate(out)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate


name: Joining of adjacent Okazaki fragments of the C-strand (Sus scrofa)


name: CSNK2-mediated phosphorylation of DVL (Drosophila melanogaster)


name: AXIN is ubiquitinated by SMURF2 (Drosophila melanogaster)


name: ATR activation at DNA DSBs (Canis familiaris)


name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Homo sapiens)


name: L-glutamate(in) + N-acetyl-L-cysteine(out) <=> L-glutamate(out) + N-acetyl-L-cysteine(in)


name: Multiubiquitination of Nek2A (Xenopus tropicalis)


name: 3 ATP = 3',3',3'-c-tri-AMP + 3 diphosphate


name: RHOV binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: H2O2 + methylamine + succinate semialdehyde => 4-(methylamino)butanoate + H2O + O2


name: DREAM complex binds the CDC6 gene promoter (Homo sapiens)


name: H2O + N-dodecanoyl-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + dodecanoate


name: IGFBP3 binds TMEM219 (Rattus norvegicus)


name: beta-D-glucose + N-hexadecanoylsphing-4-enine => beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O


name: L-glutamine(in) + L-phenylalanine(out) => L-glutamine(out) + L-phenylalanine(in)


name: 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2


name: ubiquitin-like ligase-substrate adaptor activity


name: Collagen type XXIII ectodomain shedding (Homo sapiens)


name: Formation of the SET1A complex (Schizosaccharomyces pombe)


name: Mitochondrial FPGS-1 transforms THF to THFPG (Rattus norvegicus)


name: acetyl-CoA + N-terminal L-methionyl-L-lysyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein]


name: Assembly of IFT A complex (Homo sapiens)


name: myo-inositol + NAD(+) => H(+) + myo-inosose-5 + NADH


name: (2E,6E)-farnesyl diphosphate => (1S,8aR)-delta-cadinene + diphosphate


name: Activation of TASK (Saccharomyces cerevisiae)


name: 2-cis-(+)-abscisate + O2 + reduced [NADPH--hemoprotein reductase] => (+)-8'-hydroxyabscisate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3 Fe(III)-[cytochrome c] + hydroxylamine => 3 Fe(II)-[cytochrome c] + 3 H(+) + nitric oxide


name: 1-hexadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexanoyl-CoA


name: CoA + decanedioate + H(+) => decanedioyl-CoA + H2O


name: ME3 tetramer decarboxylates MAL to PYR (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol <=> an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside


name: VEGFA-165 dimer binds VEGFR2 dimer (Xenopus tropicalis)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Danio rerio)


name: H(+)(in) + putrescine(in) => H(+)(out) + putrescine(out)


name: Hemoglobin A is protonated and carbamated causing release of oxygen (Rattus norvegicus)


name: D-glucose 6-phosphate + L-lysine => H2O + N(6)-(6-phospho-D-fructosyl)-L-lysine


name: 1,3-di-(9Z,12Z)-octadecadienoylglycerol + 9-(9Z,12Z-octadecadienoyloxy)-octadecanoate => 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + 9-hydroxy-octadecanoate


name: p62 links damaged mitochondria to LC3 (Mus musculus)


name: an N-fatty acyl-taurine + H2O => a fatty acid + taurine


name: Disassembly of COPII coated vesicle (Mus musculus)


name: ATP + guanine(out) + H2O <=> ADP + guanine(in) + H(+) + phosphate


name: Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Drosophila melanogaster)


name: (-)-deoxypodophyllotoxin + CO2 + H2O + succinate => (-)-yatein + 2-oxoglutarate + O2


name: Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Canis familiaris)


name: 1-O-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + butanoate + H(+)


name: H2O + trimetaphosphate => 2 H(+) + triphosphate


name: Interaction of PIN1 with p-IRF3 (Rattus norvegicus)


name: Complement factor I binds to extracellular Factor H:C3b (Homo sapiens)


name: an N(3)-methylcytidine in RNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in RNA + S-adenosyl-L-methionine


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Rattus norvegicus)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Caenorhabditis elegans)


name: CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Gallus gallus)


name: H(+) + L-xylulose + NADPH => NADP(+) + xylitol


name: N-acetylation of serotonin (Schizosaccharomyces pombe)


name: 2-dehydro-D-glucose + H2O2 + L-glutamate => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Schizosaccharomyces pombe)


name: H2O + L-alanyl-L-leucine <=> L-alanine + L-leucine


name: METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) (Homo sapiens)


name: Recruitment of SLP-76 to Gads (Homo sapiens)


name: 3 Fe(III)-[cytochrome c] + H2O + hydrazine = 3 Fe(II)-[cytochrome c] + 2 H(+) + NH4(+) + nitric oxide


name: 2-aminobenzenesulfonate + 2 H(+) + NADH + O2 = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH4(+)


name: NAD(P)H dehydrogenase (quinone) activity


name: PP2A dephosphorylates p-RHO to RHO (Bos taurus)


name: Recruitment of Grb2 to pFAK:NCAM1 (Bos taurus)


name: 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine = 1-tetradecanoyl-sn-glycero-2,3-cyclic phosphate + ethanolamine


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Mus musculus)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NAD(+) <=> 12alpha-hydroxy-3-oxochola-4-en-24-oate + H(+) + NADH


name: chlorophyll a + 2 H(+) <=> Mg(2+) + pheophytin a


name: 3-oxobutanoyl-[ACP] + CO2 + holo-[ACP] => acetyl-[ACP] + H(+) + malonyl-[ACP]


name: CES1trimer hydrolyses ACEI pro-drugs to ACEIs (Rattus norvegicus)


name: cholesterol 7-desaturase (NAD(P)H) activity


name: leukotriene E4(out) <=> leukotriene E4(in)


name: MTMR6 binds MTMR9 (Caenorhabditis elegans)


name: RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA (Rattus norvegicus)


name: TBC1D17 binds OPTN:RAB8A (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA => 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: EPH receptors autophosphorylate (Drosophila melanogaster)


name: LONP1 degrades mitochondrial matrix proteins (Mus musculus)


name: (2E,9Z)-hexadecadienoyl-[ACP] + H2O => (3R)-hydroxy-(9Z)-hexadecenoyl-[ACP]


name: [LarE protein]-L-cysteine + ATP + pyridinium-3,5-dicarboxylate mononucleotide = [LarE protein]-dehydroalanine + AMP + diphosphate + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide


name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Caenorhabditis elegans)


name: GM1 localizes to endosome membrane (Homo sapiens)


name: 2-oxoglutaramate + L-alanine => L-glutamine + pyruvate


name: [(1->6)-alpha-D-glucosyl](n) + sucrose <=> [(1->6)-alpha-D-glucosyl](n+1) + D-fructose


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-[(5Z,8Z,11Z,14Z)-eicosatetraenoylamino]ethyl (9Z)-octadecenoate


name: Retinoic acid activates HOXA1 chromatin (Homo sapiens)


name: BIRC(cIAP1/2) ubiquitinates RIPK1 (Mus musculus)


name: SIRT6 deacetylates RBBP8 (Caenorhabditis elegans)


name: Release of eIF4E from the inactive eIF4E:4E-BP complex  (Homo sapiens)


name: A + 2 cob(II)alamin + 2 H(+) + 2 H2O => AH2 + 2 aquacob(III)alamin


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP => Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-glucosamine


name: GDP-beta-L-fucose + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate => GDP + H(+) + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: apoTF binds 2Fe3+ to form holoTF (Rattus norvegicus)


name: a globoside NORint + UDP-alpha-D-galactose = a globoside NOR2 + H(+) + UDP


name: ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Xenopus tropicalis)


name: 2'-hydroxybiphenyl-2-sulfinate + H2O => biphenyl-2-ol + H(+) + sulfite


name: PTPN1 dephosphorylates PTK6 (Homo sapiens)


name: hexacosanoyl-CoA + O2 => (2E)-hexacosenoyl-CoA + H2O2


name: Beta-catenin binds SOX proteins (Mus musculus)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Drosophila melanogaster)


name: Glucagon-like receptor 2 binds GLP2 (Bos taurus)


name: dimethylallyl diphosphate + preechinulin = diphosphate + tardioxopiperazine B


name: CK2 phosphorylates NFE2L2 (Homo sapiens)


name: 2 H(+) + mevastatin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pravastatin lactone


name: 17alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + progesterone + reduced [NADPH--hemoprotein reductase]


name: G alpha (q) in G (q):RGS complex is inactivated (Schizosaccharomyces pombe)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane (Bos taurus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + heptadecanoyl-CoA + O2 = (9Z)-heptadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Sus scrofa)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Rattus norvegicus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Bos taurus)


name: Formation of GINS complex (Homo sapiens)


name: 1,3-di-(9Z)-octadecenoyl-2-hexadecanoylglycerol + H2O <=> 1,3-di-(9Z-octadecenoyl)-glycerol + H(+) + hexadecanoate


name: PA is dephosphorylated to DAG by LPIN (Danio rerio)


name: 2-(1-hydroxyethyl)thiamine diphosphate + 2-oxobutanoate <=> (S)-2-ethyl-2-hydroxy-3-oxobutanoate + thiamine diphosphate


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-4,8-dimethyldeca-4,8-dienoyl-CoA + H(+) + NADH => (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-4,8-dimethyldeca-4,8-dienoyl-CoA + NAD(+)


name: argininosuccinate <=> fumarate + arginine (Mus musculus)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Caenorhabditis elegans)


name: L-alanine(out) + L-glutamine(in) + Na(+)(out) => L-alanine(in) + L-glutamine(out) + Na(+)(in)


name: 2,5-didehydro-D-gluconate + H(+) + NADH <=> 5-dehydro-D-gluconate + NAD(+)


name: ACBD6 binds LCFA-CoA (Caenorhabditis elegans)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3B (GRIN3B) (Homo sapiens)


name: RIPPLY2 binds TBX6 and recruits the 26S proteasome (Homo sapiens)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Xenopus tropicalis)


name: H(+) + Na(+)(out) + 2 phosphate => diphosphate + H2O + Na(+)(in)


name: 2-oxoglutarate + [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + O2 => [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + CO2 + succinate


name: Autophagosome maturation (Drosophila melanogaster)


name: MESP1 binds the GATA4 gene (Homo sapiens)


name: Autophagosome maturation (Caenorhabditis elegans)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Danio rerio)


name: PTP-RO interacts with p-c-Kit complex (Bos taurus)


name: Association of Rb with Cyclin E:Cdk2 complexes (Bos taurus)


name: (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + O2 = (3R,6R)-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: AMPK phosphorylates PPARGC1A (Homo sapiens)


name: Inhibin-A binding to TGFBR3 (Canis familiaris)


name: ATG7:ATG3:LC3 dissociates (Schizosaccharomyces pombe)


name: CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Homo sapiens)


name: PSIP1 binds MEN1 associated with MLL2 complex (Homo sapiens)


name: Activated FGFR1 binds FRS2 (Homo sapiens)


name: 13-cis-retinol + a fatty acyl-CoA => 13-cis-retinyl ester + CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + di-(9Z)-octadecenoylglycerol


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Canis familiaris)


name: 2-oxoglutarate + 4-aminobutanoate = L-glutamate + succinate semialdehyde


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Bos taurus)


name: 1,8-cineole + diphosphate => (2E)-geranyl diphosphate + H2O


name: (7Z)-hexadecenoyl-CoA + acetyl-CoA => 3-oxo-(9Z-octadecenoyl)-CoA + CoA


name: (1S,5S,6R)-alpha-bergamotene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 3-dehydro-D-glucose + D-glucose => 3'-dehydromaltose + H2O


name: D842V PDGFRA doesn't bind sunitinib (Homo sapiens)


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Bos taurus)


name: (2R)-2-phosphoglycerate + H2O = (R)-glycerate + phosphate


name: Loading of claspin onto DNA during replication origin firing (Gallus gallus)


name: 9'-cis-neoxanthin + O2 <=> (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al + 2-cis,4-trans-xanthoxin


name: cAMP induces dissociation of inactive PKA tetramers (Xenopus tropicalis)


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Xenopus tropicalis)


name: sphinganine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoylsphinganine


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 17alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: EIF2AK4 (GCN2) dimer autophosphorylates (Homo sapiens)


name: albonoursin + 2 H2O2 => cyclo(L-phenylalanyl-L-leucyl) + 2 O2


name: N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine(1248) in human 18S rRNA + S-methyl-5'-thioadenosine


name: 4-CDP-2-C-methyl-D-erythritol + ATP => 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Rattus norvegicus)


name: H(+) + NADH + nitrate => H2O + NAD(+) + nitrite


name: LDH tetramer oxidises LACT to PYR (Bos taurus)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 11-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate


name: SARS-CoV-1 E binds BCL2L1 (Homo sapiens)


name: (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: discoidol + O2 + reduced [NADPH--hemoprotein reductase] <=> acetone + discodiene + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: Aquaporin-1 passively transports water out of cell (Homo sapiens)


name: H2O2 + L-ascorbate => 2 H2O + L-dehydroascorbate


name: S-adenosyl-L-methionine + uridine(2552) in 23S rRNA => 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Homo sapiens)


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Sus scrofa)


name: CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Canis familiaris)


name: Interaction of particulate antigens with dendritic cell receptors (Canis familiaris)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Xenopus tropicalis)


name: H2O + O2 + pyridoxal => 4-pyridoxate + H(+) + H2O2


name: 2 Na(+)(out) + tauroallocholate(out) => 2 Na(+)(in) + tauroallocholate(in)


name: p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Canis familiaris)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(in) + ATP + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: AKR1C3 reduces atRAL to atROL (Saccharomyces cerevisiae)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Bos taurus)


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Danio rerio)


name: Translocation of RIAM to plasma membrane (Bos taurus)


name: GUK1 phosphorylates 6TGMP to 6TGDP (Rattus norvegicus)


name: Recruitment of VAV and BTK to p-SLP-76 (Rattus norvegicus)


name: (+)-isomalbrancheamide C + FADH2 => (+)-premalbrancheamide + bromide + FAD + 2 H(+)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)


name: 2-oxoglutarate + 3-(N-acetyl-N-hydroxy)aminopropylphosphonate + O2 => (R)-(3-(acetylhydroxyamino)-2-hydroxypropyl)phosphonate + CO2 + succinate


name: Activated FGFR1 binds FLRT1,2,3 (Gallus gallus)


name: acetyl-CoA + S-benzyl-L-cysteine = CoA + H(+) + N-acetyl-S-benzyl-L-cysteine


name: glycyrrhetaldehyde + O2 + reduced [NADPH--hemoprotein reductase] = glycyrrhetinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLC2A5 transports fructose from extracellular region to cytosol (Sus scrofa)


name: Nuclear DUSPs dephosphorylate MAPKs (Sus scrofa)


name: diphosphate + echinulin => dimethylallyl diphosphate + tardioxopiperazine A


name: LRRC16A binds F-actin capping protein (Caenorhabditis elegans)


name: D-erythrose 4-phosphate + H2O <=> D-erythrose + phosphate


name: RNase P cleaves the 5' end of pre-tRNA (Homo sapiens)


name: p-T182 MAPKAPK5 binds DNAJB1 (Homo sapiens)


name: chloramphenicol(out) + H(+)(in) => chloramphenicol(in) + H(+)(out)


name: 2-oxoglutarate(out) + prostaglandin E2(in) => 2-oxoglutarate(in) + prostaglandin E2(out)


name: FN3K phosphorylates ketosamines (Gallus gallus)


name: ATP + H2O + K(+)(out) + Na(+)(in) = ADP + H(+) + K(+)(in) + Na(+)(out) + phosphate


name: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate


name: ALOX15 oxidises 17(S)-Hp-DHA to PDX (Homo sapiens)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Xenopus tropicalis)


name: GDP-beta-L-fucose + NADP(+) => GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH


name: 11beta-hydroxyandrost-4-ene-3,17-dione + H(+) + NADPH <=> 11beta,17beta-dihydroxyandrost-4-ene-3-one + NADP(+)


name: IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Rattus norvegicus)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Xenopus tropicalis)


name: (3R)-citramalate + CoA + H(+) => acetyl-CoA + H2O + pyruvate


name: RNASEs bind bacterial LPS, PGN (Rattus norvegicus)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Plasmodium falciparum)


name: ATP + CoA + firefly L-luciferin <=> AMP + diphosphate + L-firefly luciferyl-CoA


name: alpha-humulene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Activated FGFR1 binds FRS2 (Mus musculus)


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Caenorhabditis elegans)


name: Myristoylation of tBID by NMT1 (Homo sapiens)


name: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol <=> D-glucose + indole-3-acetyl-1D-myo-inositol


name: LDL translocates from endosome lumen to lysosome lumen (Sus scrofa)


name: (9Z,12Z)-octadecadien-1-ol + CoA + 2 NADP(+) => (9Z,12Z)-octadecadienoyl-CoA + 2 H(+) + 2 NADPH


name: ARSA removes sulfate from SM3 (Sus scrofa)


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Mus musculus)


name: a ganglioside Ac-O-7-GD2 => a ganglioside Ac-O-8-GD2


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Sus scrofa)


name: (2E)-decenedioyl-CoA + H2O = (3S)-hydroxydecanedioyl-CoA


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Mus musculus)


name: MRE11 binds cytosolic DNA (Xenopus tropicalis)


name: Formation of Malonyl-CoA from Acetyl-CoA (liver) (Schizosaccharomyces pombe)


name: SLC25A18,22 import L-Glu, H+ (Rattus norvegicus)


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Sus scrofa)


name: (-)-4'-methoxycyclopenine => 4'-methoxyviridicatin + H(+) + methyl isocyanate


name: mTORC1 phosphorylates AKT1S1 (Gallus gallus)


name: TFAP2B homodimer binds YEATS4 (Canis familiaris)


name: A + all-trans-zeta-carotene <=> AH2 + all-trans-neurosporene


name: PAOX:FAD oxidises NASPN to SPM (Mus musculus)


name: Edg-2 lysophosphatidic acid receptor binding


name: Hemoglobin A binds O2, releasing H+ and CO2 (Homo sapiens)


name: H2O + trihexadecanoylglycerol <=> dihexadecanoylglycerol + H(+) + hexadecanoate


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Xenopus tropicalis)


name: chlorohydroquinone + 2 glutathione => chloride + glutathione disulfide + H(+) + hydroquinone


name: arsenite transmembrane transporter activity


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Mus musculus)


name: 1D-myo-inositol 1,2,6-trisphosphate + H2O = 1D-myo-inositol 1,2-bisphosphate + phosphate


name: 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate <=> 16alpha,17alpha-estriol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Canis familiaris)


name: bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer (Mus musculus)


name: CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Gallus gallus)


name: CO2 + succinate + trans-4-hydroxy-L-prolyl-[protein] => 2-oxoglutarate + L-prolyl-[protein] + O2


name: H2O + N-(tetracosanoyl)-sphing-4-enine-1-phosphocholine => H(+) + N-tetracosanoyl-sphing-4-enine + phosphocholine


name: acetyl-CoA + eicosanoyl-CoA = 3-oxodocosanoyl-CoA + CoA


name: Dynamin-mediated GTP hydrolysis promotes vesicle scission (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Canis familiaris)


name: Translocation of BIM to mitochondria (Rattus norvegicus)


name: estrone 3-sulfate(out) + succinate(in) => estrone 3-sulfate(in) + succinate(out)


name: ATP + H2O + L-selenomethionine <=> diphosphate + L-adenosylselenomethionine + phosphate


name: an adenosine in tRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 3,4-dihydroxybenzoate + NAD(+) + sulfite => 4-sulfobenzoate + NADH + O2


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+) => (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + NADPH


name: cholate + NADP(+) => 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GAL3ST1 transfers sulfate to GalCer,LacCer (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoylglycerol = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: Collagen type II degradation by MMP15 (Xenopus tropicalis)


name: ADP + 5 H(+)(out) + phosphate => ATP + 4 H(+)(in) + H2O


name: Interaction of Csk with PAG (Xenopus tropicalis)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Drosophila melanogaster)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Danio rerio)