name: Synthesis of PIP3 from PIP2 by PI3K (Canis familiaris)


name: (1R,3R)-chrysanthemal + H2O + NADP(+) => (1R,3R)-chrysanthemate + 2 H(+) + NADPH


name: ERBB4 ubiquitination by WWP1/ITCH (Bos taurus)


name: ATP + dodecanoate(out) + H2O = ADP + dodecanoate(in) + H(+) + phosphate


name: TRAF6 polyubiquitinates NRIF (Gallus gallus)


name: Dissociation of phospho-Cdh1 from the APC/C complex (Bos taurus)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Dictyostelium discoideum)


name: p-PKR dimer phosphorylates CDK1 (Rattus norvegicus)


name: ROS oxidize thioredoxin (Dictyostelium discoideum)


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Saccharomyces cerevisiae)


name: H2O + N(2)-[(2E)-3-methylhex-2-enoyl]-L-glutaminate = (2E)-3-methylhex-2-enoate + L-glutamine


name: NH4(+) + thymine => 5-methylcytosine + H(+) + H2O


name: geranylgeranyl diphosphate + L-cysteinyl-[protein] => diphosphate + S-geranylgeranyl-L-cysteinyl-[protein]


name: a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+) => a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O


name: 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP => indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose


name: Activation of JAK kinases (Homo sapiens)


name: Expression of FASN regulated by NR1H2 or NR1H3 (Homo sapiens)


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Canis familiaris)


name: (9Z,12Z)-octadecadienoyl-CoA + H2O => adenosine 3',5'-bisphosphate + 2 H(+) + S-(9Z,12Z-octadecadienoyl)-4'-phosphopantetheine


name: 3-methoxybenzaldehyde + AMP + diphosphate + NADP(+) => 3-methoxybenzoate + ATP + H(+) + NADPH


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in) => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O <=> (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: FAAH2 hydrolyses AEA to AA and ETA (Xenopus tropicalis)


name: RHOB translocates to the endosome membrane (Schizosaccharomyces pombe)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: 5-formimidoyltetrahydrofolate + 2 H(+) => (6R)-5,10-methenyltetrahydrofolate + NH4(+)


name: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: benzaldehyde dehydrogenase (NAD+) activity


name: DCXR tetramer reduces L-xylulose to xylitol (Rattus norvegicus)


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Xenopus tropicalis)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + L-serine


name: MDM2 translocates to the cytosol (Danio rerio)


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Caenorhabditis elegans)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Bos taurus)


name: thiamine diphosphate phosphatase activity


name: H2O + thiamine diphosphate = H(+) + phosphate + thiamine phosphate


name: (3Z)-phytochromobilin + 2 oxidized [2Fe-2S]-[ferredoxin] <=> biliverdin IXalpha + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: p-MAPKAPK3 phosphorylates BMI1 (Gallus gallus)


name: FPGS-2 transforms THF to THFPG (Dictyostelium discoideum)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: glycine(in) + H(+)(out) + Na(+)(in) => glycine(out) + H(+)(in) + Na(+)(out)


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Homo sapiens)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Danio rerio)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+) => 1-O-alkyl-2-acyl-sn-glycerol + CDP-ethanolamine


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Homo sapiens)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Dictyostelium discoideum)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Canis familiaris)


name: TCN2:RCbl is degraded to release RCbl (Homo sapiens)


name: a 5'-end triphospho-ribonucleoside in mRNA + H2O <=> a 5'-end diphospho-ribonucleoside in mRNA + H(+) + phosphate


name: FUT3 transfers L-fucose to Gal1,3GlcNAc (Drosophila melanogaster)


name: Conversion of glyoxylate to oxalate (Caenorhabditis elegans)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Homo sapiens)


name: ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Canis familiaris)


name: (2S)-2-acetamido-4-aminobutanoate => H2O + L-ectoine


name: RHOJ GAPs stimulate RHOJ GTPase activity (Gallus gallus)


name: RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Sus scrofa)


name: 2-aminoprop-2-enoate + ethanethiol => S-ethyl-L-cysteine


name: Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA (Canis familiaris)


name: 2-oxoglutarate + 4-hydroxy-L-glutamate = 4-hydroxy-2-oxoglutarate + L-glutamate


name: Excess homocysteine yields homolanthionine and H2S (Xenopus tropicalis)


name: resorcinol + S-adenosyl-L-methionine = 3-methoxyphenol + H(+) + S-adenosyl-L-homocysteine


name: CDP(out) + UTP(in) <=> CDP(in) + UTP(out)


name: 3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine + H2O => D-glucuronate + N(2),6-disulfo-D-glucosamine


name: MRE11 binds cytosolic DNA (Mus musculus)


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Mus musculus)


name: H(+) + heptanoyl-CoA + malonyl-[ACP] = 3-oxononanoyl-[ACP] + CO2 + CoA


name: CARKD dehydrates S-NAD(P)HX to NADPH (Danio rerio)


name: cimicifugate J + CoA => (2R,3S)-piscidate + (E)-sinapoyl-CoA


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Homo sapiens)


name: ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Mus musculus)


name: UDP-glucose is oxidised to UDP-glucuronate (Mus musculus)


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Canis familiaris)


name: GALNT3 transfers GalNAc to FGF23 (Gallus gallus)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Dictyostelium discoideum)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Gallus gallus)


name: ADRBK1 binds phosphorylated SMO dimer (Homo sapiens)


name: L-tyrosyl-[protein] + NAD(+) => H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein]


name: (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(+) => 2-oxo-2H-pyran-4,6-dicarboxylate + H2O


name: 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate


name: 2-methylbutanal reductase (NADPH) activity


name: ATP binding to HSP90 triggers conformation change (Dictyostelium discoideum)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Mus musculus)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Schizosaccharomyces pombe)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Danio rerio)


name: n a quinol + n sulfur => n a quinone + n H(+) + n hydrogen sulfide


name: dihydroprecondylocarpine acetate + NADP(+) <=> H(+) + NADPH + precondylocarpine acetate


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Gallus gallus)


name: acetyl-CoA + aminomethylphosphonate = 2-N-acetamidomethylphosphonate + CoA


name: chloride:monoatomic cation symporter activity


name: CYP8B1 12-hydroxylates 4CHOL7a,27DONE (Danio rerio)


name: acetate + L-cysteine => hydrogen sulfide + O-acetyl-L-serine


name: (3R)-hydroxybutanoate dimer + H2O = 2 (R)-3-hydroxybutanoate + H(+)


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: 1,6-dihydroxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-methionine <=> 1-hydroxy-6-methoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-homocysteine


name: ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Xenopus tropicalis)


name: [eIF5A protein]-N-(4-aminobutylidene)-L-lysine + H(+) + NADH => [eIF5A protein]-deoxyhypusine + NAD(+)


name: a sphingoid base + tetracosanoyl-CoA <=> an N-tetracosanoyl-sphingoid base + CoA + H(+)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Bos taurus)


name: Misspliced GSK3beta mutants stabilize beta-catenin levels (Homo sapiens)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Bos taurus)


name: 2-epi-5-epi-valiolone + ATP = 2-epi-5-epi-valiolone 7-phosphate + ADP + H(+)


name: 6-sulfo-alpha-D-quinovose + a 1,2-diacyl-sn-glycerol => a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H2O


name: (2E,6E)-farnesyl diphosphate + S-adenosyl-L-methionine <=> H(+) + pre-sodorifen diphosphate + S-adenosyl-L-homocysteine


name: Pregn-5-ene-3,20-dione isomerizes to progesterone (Mus musculus)


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Xenopus tropicalis)


name: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose


name: 3-dehydro-6alpha-hydroxyteasterone + O2 + reduced [NADPH--hemoprotein reductase] => 3-dehydroteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III (Bos taurus)


name: MHC class I protein binding, via lateral surface


name: Association of Cdh1 with the APC/C (Mus musculus)


name: D-maltotriono-1,5-lactone + H2O <=> D-maltotrionate + H(+)


name: 2-dehydro-D-glucose + H2O2 + L-tyrosine => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Dictyostelium discoideum)


name: PAF receptor binds platelet activating factor (Bos taurus)


name: NTPDase6 hydrolyzes nucleoside diphosphates (Mus musculus)


name: SLC44A1 transports Cho from cytosol to mitochondrial matrix (Canis familiaris)


name: MTMR12 binds MTM1 (Dictyostelium discoideum)


name: 4-methylcatechol + NAD(+) + nitrite => 4-nitrotoluene + NADH + O2


name: cholesteryl octadecanoate + CoA => cholesterol + octadecanoyl-CoA


name: TP53RK phosphorylates TP53 (Mus musculus)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Gallus gallus)


name: Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS (Homo sapiens)


name: 10-hydroxydecanoate + NAD(+) <=> 10-oxodecanoate + H(+) + NADH


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: ATP + H2O + taurochenodeoxycholate 3-sulfate(in) = ADP + H(+) + phosphate + taurochenodeoxycholate 3-sulfate(out)


name: Activation of Ca-permeable Kainate receptors (Mus musculus)


name: Formation of hydroxylysyl-pyridinoline cross-links (Danio rerio)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Canis familiaris)


name: ATP-dependent H2AZ histone chaperone activity


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Rattus norvegicus)


name: D-aspartate(out) + H(+)(out) + K(+)(in) + 3 Na(+)(out) => D-aspartate(in) + H(+)(in) + K(+)(out) + 3 Na(+)(in)


name: (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + H(+) + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein] <=> (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + sarcosine


name: (3R)-3-isocyanylbutanoate + ATP + H(+) => (3R)-3-isocyanylbutanoyl-AMP + diphosphate


name: 3,4-dihydroxyphenylacetate + O2 <=> 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+)


name: H2O + tridecanoylglycerol = 2,3-didecanoyl-sn-glycerol + decanoate + H(+)


name: Cleaved fibrinogen products bind TLR4:LY96 (Homo sapiens)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADP(+) = 7,12-dioxo-lithocholate + H(+) + NADPH


name: B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain (Drosophila melanogaster)


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Sus scrofa)


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Danio rerio)


name: 26-oxolanosterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 3beta-hydroxy-lanosta-8, 24-dien-26-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 11-deoxycortisol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => cortisol + H2O + 2 oxidized [adrenodoxin]


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Sus scrofa)


name: Resynthesis of excised residue by POLB (Dictyostelium discoideum)


name: ADO oxidises 2AET to HTAU (Caenorhabditis elegans)


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Sus scrofa)


name: Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Sus scrofa)


name: RNF146 binds RibC-AXIN:TNKS complex (Sus scrofa)


name: SLC2A9 transports Fru, Glc, urate (Bos taurus)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose <=> beta-D-Gal-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: (R)-lactate(out) + citrate(in) => (R)-lactate(in) + citrate(out)


name: L-serine + NADP(+) = 2-aminomalonate semialdehyde + H(+) + NADPH


name: H(+) + NADH + NH4(+) + pentan-3-one => 3-aminopentane + H2O + NAD(+)


name: ATP + CoA + tetracosanoate <=> AMP + diphosphate + tetracosanoyl-CoA


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Gallus gallus)


name: GRB2:SOS:p-Y427-SHC1 mediated nucleotide exchange of RAS (Homo sapiens)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Plasmodium falciparum)


name: 2 H(+) + 2 H2O + 2 tellimagrandin II => 2 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + O2


name: KHK dimer phosphorylates Fru to Fru 1-P (Mus musculus)


name: acetyl phosphate + CO2 + H2O2 => H(+) + O2 + phosphate + pyruvate


name: (E)-caffeate + UDP-alpha-D-glucose <=> 1-O-[(E)-caffeoyl]-beta-D-glucose + UDP


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Sus scrofa)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Xenopus tropicalis)


name: 3-hydroxyoctadecanoyl-CoA + NADP(+) => 3-oxooctadecanoyl-CoA + H(+) + NADPH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 <=> (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate


name: D-maltotriose + O2 <=> D-maltotriono-1,5-lactone + H2O2


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Danio rerio)


name: H2O + sn-glycerol 3-phosphocholine <=> choline + H(+) + sn-glycerol 3-phosphate


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Bos taurus)


name: 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: butanoyl-CoA + H2O = adenosine 3',5'-bisphosphate + 2 H(+) + S-butanoyl-4'-phosphopantetheine


name: an N(4)-(oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] + H2O => an oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-D-GlcNAc + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein]


name: STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Mus musculus)


name: RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Rattus norvegicus)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: ATP + D-alanine + H(+) <=> D-alanyl-5'-AMP + diphosphate


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)


name: 3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde


name: ALDH3A2-2 oxidizes pristanal to pristanate (Canis familiaris)


name: GPI-bound CD14 binds LPS (Rattus norvegicus)


name: RHOD translocates to the Golgi membrane (Drosophila melanogaster)


name: 3-methylbutanoyl-CoA + S-adenosyl-L-methionine => CoA + H(+) + N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine


name: TTLLs polyglutamylate tubulin (Mus musculus)


name: PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA (Homo sapiens)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Saccharomyces cerevisiae)


name: D-glucose(out) + Na(+)(out) => D-glucose(in) + Na(+)(in)


name: Mitochondrial BTD hydrolyses BCTN (Homo sapiens)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: Detection of damage during initiation of DNA synthesis in S-phase (Plasmodium falciparum)


name: Dopaquinone transforms to Leucodopachrome (Cyclodopa) (Homo sapiens)


name: 1-hexadecanoyl-2-(7-oxoheptanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH = 1-hexadecanoyl-2-(7-hydroxyheptanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: NME1,2 hexamers phosphorylate RBV-DP (Homo sapiens)


name: (2S)-2-aminobutanoate + ATP + L-glutamate = ADP + gamma-L-glutamyl-(2S)-2-aminobutanoate + H(+) + phosphate


name: ATP + N-hexadecanoylsphing-4-enine => ADP + H(+) + N-(hexadecanoyl)-sphing-4-enine-1-phosphate


name: PIN1 binds phosphorylated PIP4K2B (Dictyostelium discoideum)


name: (3R,4R)-7,2',4'-trihydroxyisoflavanol => (6aR,11aR)-3,9-dihydroxypterocarpan + H2O


name: RLBP1 binds atROL to form RLBP1:atROL (Dictyostelium discoideum)


name: alpha-D-glucose 1-phosphate + ATP = ADP + alpha-D-glucose 1,6-bisphosphate + H(+)


name: C3PO hydrolyzes cleaved passenger strand (Drosophila melanogaster)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: SEC4C,D bind GOSR2 and STX5 (Xenopus tropicalis)


name: 4'-apo-beta-carotenal + H2O + NAD(+) <=> 2 H(+) + NADH + neurosporaxanthin


name: 3-[(E)-2-isocyanovinyl]indole + 2 CO2 + H2O + succinate => (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Mus musculus)


name: N-acetyl-alpha-D-glucosamine 1-phosphate + N-acetyl-D-glucosamine => N,N'-diacetylchitobiose + phosphate


name: H(+) + L-serine + octadecanoyl-CoA => 3-oxoeicosasphinganine + CO2 + CoA


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + CoA + H(+) => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Dictyostelium discoideum)


name: L-tryptophan + pyruvate => indole-3-pyruvate + L-alanine


name: chloromethane + S-adenosyl-L-homocysteine => chloride + S-adenosyl-L-methionine


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Rattus norvegicus)


name: diphthine methyl ester-[translation elongation factor 2] + H2O <=> diphthine-[translation elongation factor 2] + H(+) + methanol


name: FPR is a receptor for formyl peptides (Mus musculus)


name: Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Homo sapiens)


name: Syndecans 1, 2 & 4 bind VTN (Rattus norvegicus)


name: 9-cis-10'-apo-beta-carotenal + 2 O2 = (11R)-carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Homo sapiens)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Canis familiaris)


name: ATP + H2O = adenine + D-ribose 5-triphosphate


name: (S)-cystathionine ketimine + 2 H(+) + NADH = (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NAD(+)


name: alpha-D-ribose 1,5-bisphosphate + cytosine => CMP + phosphate


name: 11,12-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O


name: alpha-tubulin:GTP + Cofactor E ->  alpha-tubulin:GTP:Cofactor E (Homo sapiens)


name: Resynthesis of excised residue by POLB (Canis familiaris)


name: SMURF1 ubiquitinates RHOA (Rattus norvegicus)


name: Binding of IP3 to IP3 receptor (Xenopus tropicalis)


name: (5R)-5-hydroxy-L-lysine + GTP <=> (5R)-5-phosphooxy-L-lysine + GDP + H(+)


name: anhydrotetracycline + H(+) + NADPH + O2 <=> 5a,11a-dehydrotetracycline + H2O + NADP(+)


name: HLCS biotinylates 6x(PCCA:PCCB) (Sus scrofa)


name: AKT1S1 (PRAS40) binds mTORC1 (Canis familiaris)


name: (E,E)-feruperate + O2 + reduced [NADPH--hemoprotein reductase] => (E,E)-piperate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-alpha-D-galactose => H(+) + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP


name: glycochenodeoxycholate + NAD(+) => 7-oxoglycolithocholate + H(+) + NADH


name: (4R,5R)-4,5-dihydroxycyclohex-2-ene-1-carbonyl-CoA + NADP(+) = (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carbonyl-CoA + H(+) + NADPH


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Homo sapiens)


name: CPNEs bind PL (Dictyostelium discoideum)


name: ATP + H2O + leukotriene C4(out) <=> ADP + H(+) + leukotriene C4(in) + phosphate


name: hypoxanthine + NH4(+) => adenine + H(+) + H2O


name: S-adenosyl-L-methionine + salicylate = methyl salicylate + S-adenosyl-L-homocysteine


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Rattus norvegicus)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Canis familiaris)


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H(+) + phosphocholine


name: H(+) + N(6)-(dimethylallyl)adenosine 5'-diphosphate + NADPH + O2 <=> 9-ribosyl-trans-zeatin 5'-diphosphate + H2O + NADP(+)


name: (4R)-hydroxysphinganine(out) + ADP + H(+) + phosphate => (4R)-hydroxysphinganine(in) + ATP + H2O


name: butanoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-butanoyl-4'-phosphopantetheine


name: alpha-D-ribose 1-phosphate + ATP <=> ADP + alpha-D-ribose 1,5-bisphosphate + H(+)


name: lithocholate + UDP-alpha-D-glucuronate => H(+) + lithocholoyl-3-O-(beta-D-glucuronate) + UDP


name: Activated integrin alphaIIb beta3 binds SHC1 (Mus musculus)


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Sus scrofa)


name: Arachidonic acid is oxidised to PGG2 by PTGS1 (Rattus norvegicus)


name: acetyl-CoA + streptothricin F => CoA + H(+) + N(beta)-acetylstreptothricin F


name: (2R)-3-phosphoglycerate + H2O <=> (R)-glycerate + phosphate


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Danio rerio)


name: Cleavage of uracil by SMUG1 glycosylase (Bos taurus)


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Rattus norvegicus)


name: ornithine => putrescine + CO2 (Xenopus tropicalis)


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Canis familiaris)


name: TNPO1 binds KIF17 dimer (Caenorhabditis elegans)


name: 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+) => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 24 H(+) + 8 malonyl-CoA + 16 NADPH


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O


name: [LarE protein]-L-cysteine + ATP + pyridinium-3,5-dicarboxylate mononucleotide <=> [LarE protein]-dehydroalanine + AMP + diphosphate + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide


name: 2-oxoglutarate + N(1)-methyladenosine(58) in tRNA + O2 => adenosine(58) in tRNA + CO2 + formaldehyde + succinate


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Canis familiaris)


name: AVPR1A,2 bind AVPR antagonists (Danio rerio)


name: FDPS dimer transfers IPPP to GPP (Caenorhabditis elegans)


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Sus scrofa)


name: (+)-premalbrancheamide + chloride + FAD + 2 H(+) = (+)-malbrancheamide B + FADH2


name: H(+) + N(6),N(6)-dimethyl-L-lysine <=> CO2 + N,N-dimethyl-cadaverine


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Drosophila melanogaster)


name: TP53 family members bind PPP1R13B or TP53BP2 (Sus scrofa)


name: (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) = (4Z)-2-oxohept-4-enedioate + CO2


name: phosphate + UMP <=> alpha-D-ribose 1,5-bisphosphate + uracil


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Canis familiaris)


name: 3 2-oxoglutarate + gibberellin A12 + 3 O2 => 3 CO2 + gibberellin A25 + H(+) + H2O + 3 succinate


name: androsterone 3alpha-sulfate(out) + 2 Na(+)(out) = androsterone 3alpha-sulfate(in) + 2 Na(+)(in)


name: a (2R,3R)-flavan-3-ol + 2 NAD(+) => an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADH


name: NMRK1 phosphorylates NR to yield NMN (Drosophila melanogaster)


name: Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)


name: cyclo(L-leucyl-L-leucyl) + 4 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] => 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] + pulcherriminic acid


name: 4'-hydroxyacetophenone + H(+) + NADPH + O2 <=> 4-acetoxyphenol + H2O + NADP(+)


name: mating-type a-factor pheromone receptor activity


name: 1-hexadecanoyl-sn-glycerol + H(+) + phosphocholine => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Dictyostelium discoideum)


name: 15-cis-phytoene + A = AH2 + all-trans-phytofluene


name: HMG CoA => acetoacetic acid + acetyl CoA (Mus musculus)


name: (25S)-3-oxocholest-4-en-26-oyl-CoA + A <=> 3-oxo-cholest-4,24-dien-26-oyl-CoA + AH2


name: Cis-homodimerization of nectins (Danio rerio)


name: benzoyl-CoA + H(+) + NADPH + O2 = 2,3-epoxy-2,3-dihydrobenzoyl-CoA + H2O + NADP(+)


name: Tyrosine kinases phosphorylate the receptor (Sus scrofa)


name: Accessory proteins are recruited to the maturing virion (Homo sapiens)


name: PIAS1,3 SUMOylate MBD1 with SUMO1 (Xenopus tropicalis)


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Drosophila melanogaster)


name: (3S)-3-hydroxybutanoyl-CoA + NADP(+) => acetoacetyl-CoA + H(+) + NADPH


name: Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Homo sapiens)


name: NPC2 transfers CHOL to NPC1 (Gallus gallus)


name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Sus scrofa)


name: GSDMD (1-275) binds PIPs (Gallus gallus)


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Mus musculus)


name: Internalization of ubiquitinated FLT3 (Bos taurus)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Canis familiaris)


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Bos taurus)


name: eIF2:GTP is hydrolyzed, eIFs are released  (Canis familiaris)


name: H2O + N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine => a fatty acid + H(+) + N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphate


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Mus musculus)


name: (E)-cinnamate + O2 + reduced [NADPH--hemoprotein reductase] <=> (E)-4-coumarate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2


name: CTP + D-ribose 5-phosphate + H(+) <=> CDP-D-ribose + diphosphate


name: (R)-pantoate + ATP + beta-alanine = (R)-pantothenate + ADP + H(+) + phosphate


name: 6-dehydro-28-norteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 3-dehydro-6alpha-hydroxy-28-norteasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: phosphate + urate D-ribonucleoside = alpha-D-ribose 1-phosphate + urate


name: Protein kinase C, alpha type phosphorylates MARCKS (Mus musculus)


name: coenzyme M + methyl-Co(III)-[tetramethylammonium-specific corrinoid protein] => Co(I)-[tetramethylammonium-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: (2E,6E)-farnesyl diphosphate => (E)-2-epi-beta-caryophyllene + diphosphate


name: PEX3:PEX19:class I PMP dissociates (Drosophila melanogaster)


name: iron-nicotianamine transmembrane transporter activity


name: NUBPL transfers 4Fe-4S to Complex I subunits (Homo sapiens)


name: ent-cassa-12,15-dien-2beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-cassa-12,15-dien-2beta,3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (E)-4-coumarate + ATP + CoA <=> (E)-4-coumaroyl-CoA + AMP + diphosphate


name: RIPK3 binds HSP90:CDC37 (Rattus norvegicus)


name: Fusogenic activation of gp41 (Homo sapiens)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Dictyostelium discoideum)


name: (E)-feruloyl-AMP + CoA <=> (E)-feruloyl-CoA + AMP + H(+)


name: ISGylation of protein translation regulator 4EHP (Drosophila melanogaster)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Bos taurus)


name: Laminins:Nidogens binds collagen type IV networks (Bos taurus)


name: acetyl-CoA + hexanoyl-CoA => 3-oxooctanoyl-CoA + CoA


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Canis familiaris)


name: Expression of OSR1 in intermediate mesoderm (Homo sapiens)


name: Phosphorylation and activation of VAV (Bos taurus)


name: Ub-RibC-AXIN is degraded by the proteasome (Canis familiaris)


name: 2-hydroxy-2-methylbutanenitrile => butan-2-one + hydrogen cyanide


name: diphosphate + variecolorin L => dimethylallyl diphosphate + tardioxopiperazine A


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Homo sapiens)


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Canis familiaris)


name: TRIP11:IFT20 dissociates (Rattus norvegicus)


name: (2S)-5,5-dimethylpiperidine-2-carboxylate + A + 2 CO2 + H2O + succinate => (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + 2-oxoglutarate + AH2 + H(+) + O2


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Sus scrofa)


name: Release of docked dopamine loaded synaptic vesicle (Canis familiaris)


name: Na(+)(out) + propanoate(out) => Na(+)(in) + propanoate(in)


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Rattus norvegicus)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Xenopus tropicalis)


name: GMPS dimer transforms 6TXMP to 6TGMP (Rattus norvegicus)


name: Interaction of DAP12 and MDL-1 (Canis familiaris)


name: hypotaurine + pyruvate <=> 2-sulfinoacetaldehyde + L-alanine


name: D-alanine(out) + L-alanine(in) <=> D-alanine(in) + L-alanine(out)


name: cytidine(49) in tRNA precursor + S-adenosyl-L-methionine => 5-methylcytidine(49) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: 2 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 O2 = 2 CO2 + 2 formaldehyde + L-arginyl-[protein] + 2 succinate


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + butanoate + H(+) => 1-hexadecanoyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Caenorhabditis elegans)


name: SLIT2-bound ROBO1 binds MYO9B (Bos taurus)


name: cyclo(L-tryptophyl-L-alanyl) + dimethylallyl diphosphate <=> diphosphate + preechinulin


name: Pellino ubiquitinates IRAK1 (Sus scrofa)


name: Binding of APOBEC-1 to form editosome (Canis familiaris)


name: Proteasomal clevage of exogenous antigen (Saccharomyces cerevisiae)


name: butan-1-ol + propanoyl-CoA <=> butyl propanoate + CoA


name: arsenite + glutathionyl-S-S-[glutaredoxin] + H2O => [glutaredoxin]-dithiol + arsenate + glutathione + H(+)


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-dodecanoyl-4'-phosphopantetheine => dodecanoyl-CoA + H2O


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Mus musculus)


name: AH2 + O2 + preaustinoid A <=> A + H2O + preaustinoid A1


name: CHMP7 binds LEMD2 (Dictyostelium discoideum)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Bos taurus)


name: 3-oxochol-4-en-22-oate + ATP + CoA => 3-oxochol-4-en-22-oyl-CoA + AMP + diphosphate


name: 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate => H2O + ML-236C carboxylate


name: a fatty acid + a monoacyl-sn-glycero-3-phosphocholine + H(+) => a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O


name: Active ALK phosphorylates JAK3 (Sus scrofa)


name: Small molecule inhibitor binds RIPK1, RIPK3 (Mus musculus)


name: 2'-deoxymugineate + 2-oxoglutarate + O2 => CO2 + mugineate + succinate


name: 1-O-(9Z)-octadecenylglycerone 3-phosphate + H(+) + hexadecanoate => (9Z)-octadecen-1-ol + 1-hexadecanoylglycerone 3-phosphate


name: Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region (Homo sapiens)


name: (S)-5-carboxymethyl-tetronate + o-quinone methide = H(+) + penilactone D


name: 26S proteosome degrades ODC holoenzyme complex (Homo sapiens)


name: L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine


name: ERBB4s80:STAT5A complex translocates to the nucleus (Xenopus tropicalis)


name: 2 AMP + ATP + 2 H(+) => 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 H2O


name: L-galactono-1,4-lactone + O2 => H(+) + H2O2 + L-ascorbate


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP


name: (6R,7S)-himachala-9,11-diene + diphosphate => (2Z,6E)-farnesyl diphosphate


name: a (4R,8E)-4-hydroxysphingenine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Plasmodium falciparum)


name: PIAS4 SUMOylates RNF168 with SUMO1 (Homo sapiens)


name: a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)


name: COASY transfers an adenylyl group from ATP to PPANT (Dictyostelium discoideum)


name: (17E)-cheilanthenediol => (2E,6E,10E,14E)-geranylfarnesol + H2O


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Rattus norvegicus)


name: S-methyl-5-thio-D-ribulose 1-phosphate = 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate


name: 4-acetoxybenzyl alcohol + NAD(+) <=> 4-acetoxybenzaldehyde + H(+) + NADH


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR. (Homo sapiens)


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Mus musculus)


name: Formation of the 43S pre-initiation complex (Xenopus tropicalis)


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA <=> 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: Activated FGFR1 phosphorylates FRS2 (Canis familiaris)


name: Synthesis of dolichyl-phosphate-glucose (Mus musculus)


name: ACER2 hydrolyzes ceramide (Golgi) (Rattus norvegicus)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol


name: ST6GALNAC2 transfers sialic acid to Core 1 mucins (Gallus gallus)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Rattus norvegicus)


name: MERTK receptor binds ligands (Gas6 or Protein S) (Canis familiaris)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Mus musculus)


name: Endocytosis of Ca impermeable AMPA receptors (Bos taurus)


name: (3R)-hydroxytetradecanoyl-[ACP] + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine => H(+) + holo-[ACP] + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine


name: Conjugation of SUMO1 to UBA2:SAE1 (Danio rerio)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Schizosaccharomyces pombe)


name: SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate (Sus scrofa)


name: NAGLU hydrolyses heparan chain(2) (Mus musculus)


name: Ferriheme is transferred from Methemoglobin to Hemopexin (Sus scrofa)


name: (2S)-2-nitrosobutanedioate + H2O => N,N-dihydroxy-L-aspartate


name: Factor H binds host cell surface markers (Bos taurus)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Sus scrofa)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Mus musculus)


name: Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)


name: a 5'-end CoA-ribonucleoside in mRNA + H2O <=> 3'-dephospho-CoA + a 5'-end phospho-ribonucleoside in mRNA + H(+)


name: PTPN11 binds p-Y759-IL6ST (Rattus norvegicus)


name: H(+)(in) + L-lysyl-glycine(in) => H(+)(out) + L-lysyl-glycine(out)


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Canis familiaris)


name: NNT dimer transfers proton from NADPH to NAD+ (Xenopus tropicalis)


name: p-Y705,S727 STAT3 is acetylated (Gallus gallus)


name: (R)-mandelonitrile <=> benzaldehyde + hydrogen cyanide


name: PLOD3 binds Lysyl hydroxylated collagen propeptides (Mus musculus)


name: L-alanine + oxomalonate <=> aminomalonate + pyruvate


name: a ganglioside GalNAc-GD1a (d18:1(4E)) + H(+) + UDP => a ganglioside GD1a (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Dictyostelium discoideum)


name: (3S)-hydroxydecanoyl-CoA + NAD(+) => 3-oxodecanoyl-CoA + H(+) + NADH


name: 3beta-hydroxyandrost-5-en-17-one + O2 + reduced [NADPH--hemoprotein reductase] <=> 3beta,16alpha-dihydroxy-androst-5-en-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (E)-ferulate + ATP + H(+) <=> (E)-feruloyl-AMP + diphosphate


name: 2 H(+) + NADPH + oxidized [flavodoxin] => NADP(+) + reduced [flavodoxin]


name: 7,8-dihydroneopterin 2',3'-cyclic phosphate + H2O <=> 7,8-dihydroneopterin 2'-phosphate + H(+)


name: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O <=> (2S)-2-isopropylmalate + CoA + H(+)


name: 1'-[1-acyl-2-(9-hydroxy-(10E,12Z)-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1,2-diacyl-sn-glycero-3-phospho]-glycerol + H2O = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + 9-hydroxy-(10E,12Z)-octadecadienoate + H(+)


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Mus musculus)


name: 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + H(+) + NADPH = 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-4H,6H,7H,8H-pyrrolo[1,2-a]pyrazine + NADP(+)


name: (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: L-threonine + NAD(+) = aminoacetone + CO2 + NADH


name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Bos taurus)


name: aurachin C epoxide = 2-hydroxy-1a-methyl-7a-[(2E,6E)-farnesyl]-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one


name: a quinol + fumarate => a quinone + succinate


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Bos taurus)


name: NAD(+) + UDP-N-acetyl-alpha-D-quinovosamine = H(+) + NADH + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose


name: cGMP binds CNG channel to form cGMP:CNG channel (Drosophila melanogaster)


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Mus musculus)


name: PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Homo sapiens)


name: US11:HLA binds DERL1:TMEM129:Ub:UBE2J2,UBE2K:VIMP:VCP (Homo sapiens)


name: ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Danio rerio)


name: (R)-synephrine + H(+) + S-adenosyl-L-homocysteine => (R)-octopamine + S-adenosyl-L-methionine


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Sus scrofa)


name: A + all-trans-lycopene + dimethylallyl diphosphate + H2O = AH2 + diphosphate + nonaflavuxanthin


name: 7-methylmellein + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 7-carboxymellein + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: (2E,6E,10E)-geranylgeranyl diphosphate = cattleyene + diphosphate


name: all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity


name: Receptors CCR3, 4 and 5 bind CCL5 ligand (Gallus gallus)


name: SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Rattus norvegicus)


name: (S)-lactate + O2 <=> acetate + CO2 + H2O


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Sus scrofa)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Drosophila melanogaster)


name: L-asparaginyl-[protein] + UDP-alpha-D-glucose <=> H(+) + N(4)-(beta-D-glucosyl)-L-asparaginyl-[protein] + UDP


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Xenopus tropicalis)


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Mus musculus)


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) = 3-(3,4-dihydroxyphenyl)pyruvate + H(+) + NADH


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Plasmodium falciparum)


name: Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Bos taurus)


name: SCD5 desaturates ST-CoA to OLE-CoA (Drosophila melanogaster)


name: SPARC gene transcription is stimulated by ERBB4s80 (Homo sapiens)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Canis familiaris)


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Dictyostelium discoideum)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Xenopus tropicalis)


name: ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Mus musculus)


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Xenopus tropicalis)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + maniladiol + oxidized [NADPH--hemoprotein reductase]


name: Dissociation of L13a from the 60s ribosomal subunit (Homo sapiens)


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Gallus gallus)


name: kaempferol + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + quercetin


name: 3'-phosphoadenylyl sulfate + a primary amine = a sulfamate + adenosine 3',5'-bisphosphate + 2 H(+)


name: PDE6D dissociates from ARL13B:INPP5E (Gallus gallus)


name: STAT3,STAT6 bind p-Y-IL4R (Rattus norvegicus)


name: Initiation of SAHF formation (Canis familiaris)


name: MT3 exchanges zinc for copper (Danio rerio)


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Drosophila melanogaster)


name: anthranilate + 2 H(+) + NADPH + O2 = 2,3-dihydroxybenzoate + NADP(+) + NH4(+)


name: apo-[corrinoid adenosyltransferase] + cob(II)alamin = cob(II)alamin-[corrinoid adenosyltransferase]


name: H2O + tetrathionate <=> H(+) + sulfate + sulfur + thiosulfate


name: 2-oxoglutarate + ATP + hydrogencarbonate <=> (S)-oxalosuccinate + ADP + H(+) + phosphate


name: L-lysyl-[histone] + S-adenosyl-L-methionine <=> H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: Formation of Pol zeta complex (Sus scrofa)


name: 4-methoxybenzaldehyde + AMP + diphosphate + NADP(+) => 4-methoxybenzoate + ATP + H(+) + NADPH


name: 1-pyrroline-2-carboxylate + H(+) + NADH => L-proline + NAD(+)


name: 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-octadecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Bos taurus)


name: AKT1 phosphorylates NOTCH4 (Homo sapiens)


name: HMGB1 release from cells (Canis familiaris)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Caenorhabditis elegans)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 5-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 12alpha-hydroxy-3-oxochola-4-en-24-oate + NAD(+) <=> 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(+) + NADH


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Mus musculus)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Canis familiaris)


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Rattus norvegicus)


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2 <=> 2-dehydro-D-glucose + an aliphatic amine + H2O2


name: PKC phosphorylates ROBO3.1 (Canis familiaris)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Danio rerio)


name: IRAK2 induces TRAF6 oligomerization initiated from endosomal compartments (Canis familiaris)


name: L-cysteine(out) + L-methionine(in) => L-cysteine(in) + L-methionine(out)


name: citrate(out) + phosphoenolpyruvate(in) => citrate(in) + phosphoenolpyruvate(out)


name: CBL ubiquitinates FRS2 and FGFR3 (Canis familiaris)


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Saccharomyces cerevisiae)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphoethanolamine + acetate + H(+)


name: 3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O


name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Xenopus tropicalis)


name: SULTs transfer (SO4)2- group to PREG (Drosophila melanogaster)


name: 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase]


name: (2E,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H(+) + NADPH = (11Z,14Z,17Z)-eicosatrienoyl-CoA + NADP(+)


name: 1-O-(1Z-hexadecenyl)-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+) => 1-O-(1Z-hexadecenyl)-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH


name: albendazole S-oxide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => albendazole + O2 + reduced [NADPH--hemoprotein reductase]


name: (R)-pantetheine + ATP => (R)-4'-phosphopantetheine + ADP + H(+)


name: Activation of Calcineurin (Plasmodium falciparum)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine => 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: Surface deployment of platelet dense granule membrane components (Canis familiaris)


name: Activated Adenylate cyclase catalyses cAMP synthesis (Homo sapiens)


name: Luteinizing hormone receptor can bind LH (Homo sapiens)


name: PCK1 phosphorylates OA to yield PEP (Homo sapiens)


name: Phospholipase C-gamma1 binds to the activated EGF receptor (Canis familiaris)


name: WNTs are secreted in exosomes (Rattus norvegicus)


name: aldosterone + H(+) + NADPH = 5beta-dihydroaldosterone + NADP(+)


name: L-alanyl-tRNA(Ala) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine = H(+) + tRNA(Ala) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-N(6)-(L-alanyl)-L-lysyl-D-alanyl-D-alanine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) <=> 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + a 1,2-diacyl-sn-glycerol


name: CoA + H(+) + N(2)-phenylacetyl-L-glutamine => L-glutamine + phenylacetyl-CoA


name: choline + NAD(+) = betaine aldehyde + H(+) + NADH


name: 1D-myo-inositol 1,3,4-trisphosphate + H2O = 1D-myo-inositol 1,3-bisphosphate + phosphate


name: ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE (Bos taurus)


name: aminotriazole transmembrane transporter activity


name: H2O + limonene 1,2-epoxide + NADP(+) => (4S)-limonene + H(+) + NADPH + O2


name: Basigin binds CD98 complex (Homo sapiens)


name: Caspase mediated cleavage of beta-catenin (Danio rerio)


name: beta-nicotinamide D-ribonucleotide + H2O = D-ribose 5-phosphate + H(+) + nicotinamide


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(9Z-octadecenoyl) ethanolamine => H2O + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine => [thioredoxin]-dithiol + H(+) + phosphate + sarcosine


name: USP16,USP21 deubiquitinate Histone H2A (Canis familiaris)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Canis familiaris)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Dictyostelium discoideum)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Dictyostelium discoideum)


name: L-homoserine + succinyl-CoA => CoA + O-succinyl-L-homoserine


name: Kinesins move along microtubules consuming ATP (Rattus norvegicus)


name: PGM2:Mg2+ isomerises R1P to R5P (Dictyostelium discoideum)


name: MKRN1 polyubiquitinates PTEN (Dictyostelium discoideum)


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Xenopus tropicalis)


name: alpha-pinene oxide => (Z)-2-methyl-5-isopropylhexa-2,5-dienal


name: FNTB inhibitors bind FNTA:FNTB (Danio rerio)


name: chloride(in) + dopamine(in) + 2 Na(+)(in) => chloride(out) + dopamine(out) + 2 Na(+)(out)


name: The FA anion diffuses away laterally from UCP (Caenorhabditis elegans)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Bos taurus)


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Danio rerio)


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Schizosaccharomyces pombe)


name: (indol-3-yl)acetate(out) + a dicarboxylate(in) => (indol-3-yl)acetate(in) + a dicarboxylate(out)


name: Cytoslic carboxylases translocate to mitochondrial matrix (Sus scrofa)


name: a guaiacol + H(+) + S-adenosyl-L-homocysteine => a catechol + S-adenosyl-L-methionine


name: (2E)-geranyl diphosphate = (1S,5S)-beta-pinene + diphosphate


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Dictyostelium discoideum)


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Drosophila melanogaster)


name: (2R)-2,3-bisphosphoglycerate + H2O <=> (2R)-2-phosphoglycerate + phosphate


name: PAO:FAD oxidises NASPM to PTCN (Caenorhabditis elegans)


name: tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Canis familiaris)


name: L-arginine + S-adenosyl-L-methionine <=> H(+) + N(omega)-methyl-L-arginine + S-adenosyl-L-homocysteine


name: gentamicin X2 + methylcob(III)alamin + S-adenosyl-L-methionine = 5'-deoxyadenosine + cob(III)alamin + geneticin + L-methionine


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: p-STAT5 dissociates from the receptor complex (Mus musculus)


name: CTP(out) + dUMP(in) <=> CTP(in) + dUMP(out)


name: 3-hydroxy-4-methylanthranilate + H(+) + L-alanine => 3-hydroxy-4-methyl-L-kynurenine + H2O


name: acetyl-CoA + spermidine <=> CoA + H(+) + N(1)-acetylspermidine


name: (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2 => N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-alanine + O2


name: CDK2 phosphorylates TP53 (Drosophila melanogaster)


name: methionyl-initiator methionine tRNA binding


name: ORC2 binds ORC3 (Dictyostelium discoideum)


name: Activation of ISG15 by UBA7 E1 ligase (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: dGMP(in) + NAD(+)(out) => dGMP(out) + NAD(+)(in)


name: a primary linear alkyl sulfate ester + H2O <=> a primary alcohol + H(+) + sulfate


name: Binding of ATP to P2X receptors (Xenopus tropicalis)


name: Activated MAPKs phosphorylate MAP2K1 (Danio rerio)


name: FA core complex:HSP70s binds PKR (Xenopus tropicalis)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA = [N,O(9)-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + CoA


name: Separation of elongating transcript from template (Gallus gallus)


name: Proteinase-activated receptors can bind thrombin (Xenopus tropicalis)


name: an inositol phosphomannosyl-alpha-1->6-inositol-1-phospho-N-acyl-4R-hydroxysphinganine + H2O = alpha-D-mannosyl-di-(inositol-1-phosphate) + an N-acyl-(4R)-4-hydroxysphinganine + H(+)


name: Beclin-1 complex phosphorylates PtdIns (Sus scrofa)


name: PIAS1 SUMOylates SAFB with SUMO1 (Mus musculus)


name: 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate => 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O


name: a ganglioside Ac-O-8-GD3(d18:1(4E)) = a ganglioside Ac-O-9-GD3(d18:1(4E))


name: SRD5A3 reduces pPNOL to DCHOL (Saccharomyces cerevisiae)


name: H2O + L-aspartate + O2 => H2O2 + NH4(+) + oxaloacetate


name: NKG2D homodimer interacting with ligands (Rattus norvegicus)


name: Interaction of KIT and sSCF (Rattus norvegicus)


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Canis familiaris)


name: glutathione amide disulfide + 2 H2O => 2 glutathione amide + H2O2


name: 4-aminobutanoyl-[BtrI ACP] + CO2 => gamma-L-glutamyl-[BtrI ACP] + H(+)


name: 3-dehydrocarnityl-CoA + CoA = acetyl-CoA + N,N,N-trimethylglycyl-CoA


name: FUT2 transfers Fuc to LeA to form LeB (Xenopus tropicalis)


name: MIB2 ubiquitinates CFLAR  (Canis familiaris)


name: festuclavine + NAD(+) <=> 6,8-dimethyl-6,7-didehydroergoline + H(+) + NADH


name: Casein kinase II phosphorylates STARD10 (Canis familiaris)


name: The complex of RUNX3, SMAD3 and SMAD4 binds the CDKN1A gene promoter (Homo sapiens)


name: 4-hydroxy-6-methylpretetramide + NADPH + O2 => 4-dedimethylamino-4-oxo-anhydrotetracycline + H2O + NADP(+)


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Caenorhabditis elegans)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Mus musculus)


name: PGM1:Mg2+ isomerises G6P to G1P (Dictyostelium discoideum)


name: 5-hydroxyuridine + ATP = 5-hydroxyuridine 5'-phosphate + ADP + H(+)


name: FGFRL1 binds SPRED1/2 (Canis familiaris)


name: DHCR7 reduces 7-dehydroCHOL to CHOL (Mus musculus)


name: 2-oxoglutarate + a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + O2 <=> a 5'-end triphospho-guanosine-ribonucleotide-snRNA + CO2 + formaldehyde + H(+) + succinate


name: p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS (Homo sapiens)


name: ETA is phosphorylated to PETA by CHK/ETNK (Mus musculus)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Gallus gallus)


name: 2xPDKX:2xZn2+ phosphorylates PDX (Plasmodium falciparum)


name: ATP + H2O + L-methionyl-L-alanine(out) = ADP + H(+) + L-methionyl-L-alanine(in) + phosphate


name: cladofulvin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 2 nataloe emodin + O2 + reduced [NADPH--hemoprotein reductase]


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Xenopus tropicalis)


name: Recruitment of transition zone proteins (Mus musculus)


name: GALK1 phosphorylates Gal to Gal1P (Rattus norvegicus)


name: Association of CCT/TriC with sphingosine kinase 1 (Drosophila melanogaster)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Drosophila melanogaster)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Gallus gallus)


name: ZnT5 transports zinc into the golgi apparatus (Homo sapiens)


name: a dicarboxylate(out) + urate(in) => a dicarboxylate(in) + urate(out)


name: 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O <=> 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3] + succinate


name: 27-hydroxysterol binds ESR1, ESR2 (Rattus norvegicus)


name: (R)-carnitine(out) + 2-oxoglutarate(in) => (R)-carnitine(in) + 2-oxoglutarate(out)


name: H2O + plasmodiophorol A => plasmodiophorol C


name: N-acetylation of serotonin (Saccharomyces cerevisiae)


name: acetyl-CoA + S-methyl-L-cysteine => CoA + H(+) + N-acetyl-S-methyl-L-cysteine


name: beta-D-glucosylceramide + H2O = a  beta-D-glucosyll-(1<->1')-sphingoid base + a fatty acid


name: SGK1 phosphorylates MDM2 (Rattus norvegicus)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Canis familiaris)


name: dAMP + 2 H(+) + 2 phosphate => dATP + 2 H2O


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Dictyostelium discoideum)


name: 4-nitrobenzaldehyde + H(+) + NADPH <=> 4-nitrobenzyl alcohol + NADP(+)


name: H2O + trans-2,3-epoxysuccinate => (2R,3S)-tartrate


name: (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA <=> (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H2O


name: 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => 1-O-alkyl-3-acylglycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: (2E)-octenoyl-[ACP] + H(+) + NADPH = NADP(+) + octanoyl-[ACP]


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Dictyostelium discoideum)


name: dodecanoyl-CoA + H2O + oxaloacetate => (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+)


name: Nephrin dimer:KIRREL binds FYN (Caenorhabditis elegans)


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Mus musculus)


name: 4alpha-methyl-5alpha-cholest-8-en-3-one + H(+) + NADPH = 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+)


name: K+-independent Li+/Ca2+ exchanger transport (Canis familiaris)


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine => CMP-N-acetyl-beta-neuraminate + N-acetyl-beta-lactosamine


name: 4 (R)-3-phenyllactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine => 8 AMP + 8 diphosphate + 8 H(+) + PF1022B + 4 S-adenosyl-L-homocysteine


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + O2 + reduced [NADPH--hemoprotein reductase] => (20S)-ginsenoside C-K + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: sucrose + UDP-alpha-D-galactose => H(+) + loliose + UDP


name: CoA + H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate => acetyl-CoA + alpha-D-galactosamine 1-phosphate


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Mus musculus)


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Sus scrofa)


name: IL35 binds IL-12RB2:IL6ST receptor (Sus scrofa)


name: SOAT1,2 transfer acyl group to CHOL forming CHEST (Xenopus tropicalis)


name: HRH3 binds Hist (Caenorhabditis elegans)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)


name: 3-methyl-2-oxobutanoate + L-isoleucine => (S)-3-methyl-2-oxopentanoate + L-valine


name: Complement factor B binds to the hydrolyzed form of C3 (Gallus gallus)


name: a (3R)-3-hydroxyacyl-CoA + NADP(+) = a 3-oxoacyl-CoA + H(+) + NADPH


name: HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Mus musculus)


name: 3-oxoadipate + succinyl-CoA <=> 3-oxoadipyl-CoA + succinate


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + 2-hexadecanoyl-sn-glycero-3-phosphocholine => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + a 2-acyl-sn-glycero-3-phosphocholine


name: Tryptophan is hydroxylated (Homo sapiens)


name: CDO binds promyogenic cadherins (Rattus norvegicus)


name: USP8 deubiquitinates STAM2:HGS (Rattus norvegicus)


name: 3-methylcatechol + H2O + NAD(+) => 2-hydroxytoluene + H(+) + NADH + O2


name: Hemes bind to CLEC1B dimer (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: H2O + L-isoleucine + NAD(+) => (S)-3-methyl-2-oxopentanoate + H(+) + NADH + NH4(+)


name: Multiphospho-CERT1-2 binds PPM1L, VAPA/B (Homo sapiens)


name: 2-oxoglutarate + a 5-hydroxymethyl-2'-deoxycytidine in DNA + O2 => a 5-formyl-2'-deoxycytidine in DNA + CO2 + H2O + succinate


name: ACAD10 dehydrogenates S-2MPDA-CoA (Caenorhabditis elegans)


name: Tyrosine kinases phosphorylate the receptor (Homo sapiens)


name: Translocation of p21 to the nucleus (Gallus gallus)


name: MECP2 mutants P302R,K304E,K305R,R306C,(R306H) do not bind NCoR/SMRT complex (Homo sapiens)


name: all-trans-zeaxanthin + 2 O2 = 2 (3R)-hydroxy-beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: Phosphorylated RHOU translocates to the endosome membrane (Gallus gallus)


name: G alpha t2 binds and activates PDE6 (Homo sapiens)


name: UCHL1, UCHL3 cleave ubiquitin adducts (Gallus gallus)


name: IL12B translocates from the cytosol to the extracellular region (Mus musculus)


name: AH2 + formaldehyde + N(6)-methyl-L-lysyl-[protein] => A + H2O + N(6),N(6)-dimethyl-L-lysyl-[protein]


name: phosphate + uridine <=> alpha-D-ribose 1-phosphate + uracil


name: ethyl (9Z)-octadecenoate + H2O <=> (9Z)-octadecenoate + ethanol + H(+)


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Sus scrofa)


name: 2-methylhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: BESTs transport cytosolic HCO3- to extracellular region (Homo sapiens)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> 1,4-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: holo-[ACP] + malonyl-CoA <=> CoA + malonyl-[ACP]


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Mus musculus)


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + phosphate => alpha-D-galactose 1-phosphate + N-acetyl-D-glucosamine


name: DLST transfers glutaryl to CoA (Sus scrofa)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Sus scrofa)


name: galactitol + NADP(+) = D-galactose + H(+) + NADPH


name: biochanin A 7-O-beta-D-glucoside + malonyl-CoA <=> biochanin A 7-O-beta-D-glucoside 6''-O-malonate + CoA


name: ATM recognizes H2AFX-Nucleosomes (Bos taurus)


name: ATP + N(4)-acetylcytidine = ADP + H(+) + N(4)-acetylcytidine 5'-phosphate


name: (PTN,MDK):PTPRZ oligomerizes (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR2b (Rattus norvegicus)


name: PIP3 recruits PDK1 and AKT to the membrane (Caenorhabditis elegans)


name: S-adenosyl-L-methionine + xanthosine => 7-methylxanthosine + S-adenosyl-L-homocysteine


name: dihydrochanoclavine-I aldehyde + NADP(+) <=> chanoclavine-I aldehyde + H(+) + NADPH


name: ACSM2B-like proteins transform ST to ST-CoA (Canis familiaris)


name: cannabinerolate + O2 => Delta(9)-tetrahydrocannabinolate + H2O2


name: ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate => AMP + diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Caenorhabditis elegans)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 <=> (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO2 + H2O + succinate


name: 2-oxoadipate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminoadipate


name: GPI dimer isomerizes Fru(6)P to G6P (Bos taurus)


name: 3-hydroxy-3-methylbut-1-ene + 2 H2O + NADP(+) => 2-methylbutan-2-ol + H(+) + NADPH + O2


name: (R)-pantetheine + ATP <=> (R)-4'-phosphopantetheine + ADP + H(+)


name: levoglucosan + NAD(+) <=> 3-dehydrolevoglucosan + H(+) + NADH


name: IL1 receptor antagonist protein binds Interleukin 1 receptors (Canis familiaris)


name: LIPA hydrolyses sterol esters to sterols and fatty acids (Canis familiaris)


name: CBL ubiquitinates FRS2 and FGFR3 (Mus musculus)


name: dehydrospermidine + H(+) + NADH => NAD(+) + spermidine


name: a (3R)-hydroxyacyl-[ACP] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose <=> a UDP-2-acetamido-3-{[(3R)-3-hydroxyacyl]amino}-2,3-dideoxy-alpha-D-glucopyranose + H(+) + holo-[ACP]


name: citrate(out) + trans-aconitate(in) = citrate(in) + trans-aconitate(out)


name: Cytosolic PP2A dephosphorylates phosphorylated PER complexed with DCO (Drosophila melanogaster)


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Caenorhabditis elegans)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphoglycerol + H2O => (9Z)-octadecenoate + a 2-acyl-sn-glycero-3-phosphoglycerol + H(+)


name: DIBOA beta-D-glucoside + H2O => D-glucose + DIBOA


name: 1-deoxy-11beta-hydroxypentalenate + CO2 + succinate => 1-deoxypentalenate + 2-oxoglutarate + O2


name: P2Y14 receptor can bind to UDP-glucose (Gallus gallus)


name: Recruitment of Dna2 endonuclease (Rattus norvegicus)


name: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Bos taurus)


name: (9Z)-tetradecenoyl-CoA + H2O <=> (9Z)-tetradecenoate + CoA + H(+)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Saccharomyces cerevisiae)


name: Formation of the CTF18-RFC(7s) complex (Gallus gallus)


name: 1,2-dioctanoyl-sn-glycero-3-diphosphate + H2O = 1,2-dioctanoyl-sn-glycero-3-phosphate + H(+) + phosphate


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Xenopus tropicalis)


name: alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose => alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H(+)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Mus musculus)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Sus scrofa)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + 2 H2O <=> 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + 2 chloride + 2 H(+)


name: Haptoglobin-related Protein binds Hemoglobin (Homo sapiens)


name: precorrin-6B + S-adenosyl-L-methionine => CO2 + H(+) + precorrin-7 + S-adenosyl-L-homocysteine


name: Inactive G alpha (i) reassociates with G beta:gamma (Canis familiaris)


name: Beta-defensins are secreted (Homo sapiens)


name: EP2 and EP4 receptors can bind PGE2 (Sus scrofa)


name: adenosine 5'-phosphosulfate + ATP <=> 3'-phosphoadenylyl sulfate + ADP + H(+)


name: 27-hydroxycholesterol is 7alpha-hydroxylated (Xenopus tropicalis)


name: n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate <=> n adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate + n H(+)


name: (R)-2-hydroxyglutarate + NAD(+) <=> 2-oxoglutarate + H(+) + NADH


name: H2O + luteolin 7-O-beta-D-glucoside = beta-D-glucose + luteolin


name: E2F6 binds BRCA1 gene promoter (Homo sapiens)


name: CoA + pseudomonic acid C--holothin => holothin + pseudomonoyl-CoA C


name: PMM1,2 isomerise Man6P to Man1P (Dictyostelium discoideum)


name: H(+) + malonyl-[ACP] = acetyl-[ACP] + CO2


name: NREH hydrolyses atREs to atROL and FAs (Homo sapiens)


name: 2-oxoglutarate + 3-hydroxy-L-phenylalanine <=> 3-(3-hydroxyphenyl)pyruvate + L-glutamate


name: aspulvinone E + 2 dimethylallyl diphosphate <=> aspulvinone H + 2 diphosphate


name: Defective HGSNAT does not acetylate Heparan chain(1) (Homo sapiens)


name: dodecanoate + 2 H(+) + NADH = dodecanal + H2O + NAD(+)


name: L-tyrosine + S-adenosyl-L-methionine = 3-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: MFAP2, MFAP5 bind microfibrils (Danio rerio)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: AMP + H(+) + nebramycin 5' => carbamoyl adenylate + tobramycin


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Danio rerio)


name: SARS-CoV-1 nsp3 deubiquinates K63-linked pUb oligo-TRAF6 (TLR7/8 signaling) (Homo sapiens)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Canis familiaris)


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Canis familiaris)


name: PC is converted to PS by PTDSS1 (Bos taurus)


name: CHEK1 phosphorylates BRCA2 (Homo sapiens)


name: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ATP <=> 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)


name: KDM5A demethylates histone H3 trimethyllysine-4 (H3K4me3) (Homo sapiens)


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Homo sapiens)


name: etheroleate + H2O => (13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: Phosphorylation of Syntaxin-4 (Drosophila melanogaster)


name: Cdc45 associates with the pre-replicative complex at the origin (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate => (-)-(E)-beta-caryophyllene + diphosphate


name: (2Z,6Z)-farnesyl diphosphate => (Z)-gamma-bisabolene + diphosphate


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Caenorhabditis elegans)


name: CoA + NAD(+) + phenylglyoxylate <=> benzoyl-CoA + CO2 + NADH


name: propanoyl-CoA + succinate => propanoate + succinyl-CoA


name: 1/3-PP-IP5 transports from the cytosol to the nucleus (Homo sapiens)


name: alpha-D-glucose + D-maltotriose => D-maltotetraose + H2O


name: PLC-gamma1 hydrolyses PIP2 (Saccharomyces cerevisiae)


name: SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)


name: a 1-acyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycerol + phosphate


name: p62 is recruited and forms a complex with TRAF6 (Gallus gallus)


name: L-serine(out) + Na(+)(out) => L-serine(in) + Na(+)(in)


name: AMP + diphosphate + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] => ATP + docosanoate + holo-[(phenol)carboxyphthiodiolenone synthase]


name: a ganglioside GD1b + N-acetylneuraminate => a ganglioside GT1b + H2O


name: (2S)-2-hydroxy-2-phenylpropanenitrile => acetophenone + hydrogen cyanide


name: (d)ADP + ADP <=> (d)AMP + ATP (AK1) (Bos taurus)


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Caenorhabditis elegans)


name: Formation of MSH1:PMS2 Complex (Mus musculus)


name: fumitremorgin C + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 12alpha,13alpha-dihydroxyfumitremorgin C + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + siroheme <=> 12,18-didecarboxysiroheme + 2 CO2


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated FGFR1:p-FRS bind to PPTN11 (Bos taurus)


name: C-X-C motif chemokine 12 receptor activity


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Gallus gallus)


name: TDG excises 5-formylcytosine (Canis familiaris)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Mus musculus)


name: bisdemethoxycurcumin + CO2 + 2 CoA => (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O


name: IL34 dimer binds SDC1 (Rattus norvegicus)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Gallus gallus)


name: SUMOylation of DAXX with SUMO1 (Xenopus tropicalis)


name: SUMOylation of NPM1 with SUMO2,3 (Mus musculus)


name: (2E)-2-hydroxypenta-2,4-dienoate + H(+) + succinate => (2E,4Z)-2-hydroxy-6-oxononadienedioate + H2O


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Caenorhabditis elegans)


name: AKT interacts and phosphorylates Cot (Homo sapiens)


name: 10-deoxymethymycin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + methymycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (2E,6E)-farnesyl diphosphate + H2O => diphosphate + valerianol


name: 2-oxoglutarate + UDP-4-amino-4-deoxy-beta-L-arabinose <=> L-glutamate + UDP-beta-L-threo-pentopyranos-4-ulose


name: CDK4 phosphorylates RUNX2 (Canis familiaris)


name: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> an (11Z)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Bos taurus)


name: an acyl-CoA + sn-glycerol 3-phosphate => a 1-acyl-sn-glycero-3-phosphate + CoA


name: NAD(+) + propane-1,2-diol 1-phosphate => H(+) + hydroxyacetone phosphate + NADH


name: Melanin-concentrating hormone receptors bind MCH (Xenopus tropicalis)


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Canis familiaris)


name: GSDMD oligomerizes into arc-, slit-shaped structures (Homo sapiens)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Homo sapiens)


name: GLI2,3 are degraded by the proteasome (Drosophila melanogaster)


name: PRMT1 arginine-methylates RUNX1 (Sus scrofa)


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-oxoisoapionate + ATP <=> 3-oxoisoapionate 4-phosphate + ADP + H(+)


name: 3,4-dihydroxyphenylacetaldehyde + H2O + NAD(+) <=> 3,4-dihydroxyphenylacetate + 2 H(+) + NADH


name: SMAD3 binds STUB1 (CHIP) (Canis familiaris)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Homo sapiens)


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + O2 => CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + succinate


name: H(+) + NADPH + O2 + octan-3-one = H2O + NADP(+) + pentyl propanoate


name: RETSAT reduces atROL to at-13,14-dhROL (Homo sapiens)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Canis familiaris)


name: Hydrolysis of phosphatidylcholine (Xenopus tropicalis)


name: oxidoreductase activity, acting on the CH-NH2 group of donors


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Sus scrofa)


name: L-cystine(in) + L-leucine(out) => L-cystine(out) + L-leucine(in)


name: ATP hydrolysis by HSP70 (Dictyostelium discoideum)


name: ADRM1 binds 26S proteasome (Caenorhabditis elegans)


name: ATP + H2O + hydrogenselenide => AMP + 2 H(+) + phosphate + selenophosphate


name: Membrane localised SGG phosphorylates ARR (Drosophila melanogaster)


name: PLC beta-mediated PIP2 hydrolysis (Drosophila melanogaster)


name: Formation of MCM2-7 complex (Mus musculus)


name: a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine => H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide


name: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 9beta-pimara-7,15-dien-19-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 7alpha,25-dihydroxycholesterol + NAD(+) => 7alpha,25-dihydroxy-4-cholesten-3-one + H(+) + NADH


name: curcumin + 2 H(+) + 2 NADPH => 2 NADP(+) + tetrahydrocurcumin


name: TRAF6 is auto-ubiquitinated (Sus scrofa)


name: HYKK phosphorylates 5HLYS (Xenopus tropicalis)


name: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] => 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Transport of MHC heterotrimer to ER exit site (Rattus norvegicus)


name: TAF1 phosphorylates TP53 (Xenopus tropicalis)


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Danio rerio)


name: ISGylation of E2 conjugating enzymes (Homo sapiens)


name: beta-D-fructose 1,6-bisphosphate + methylglyoxal => 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + D-glyceraldehyde 3-phosphate


name: Gbeta:gamma activation of PLC beta (Xenopus tropicalis)


name: (25S)-3-oxocholest-4-en-26-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => (25S)-3-oxocholest-4-en-26-al + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Plasmodium falciparum)


name: (2E)-octenedioyl-CoA + H2O <=> (3S)-hydroxyoctanedioyl-CoA


name: O2 + 4 semiviriditoxin <=> 2 (M)-viriditoxin + 2 H2O


name: GSDME variant does not bind PIPs (Homo sapiens)


name: p-STAT1 dissociates from IL6ST:IL6ST (Sus scrofa)


name: Formation of ADAR2  homodimer (Xenopus tropicalis)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA


name: Galanin receptors can bind galanin (Gallus gallus)


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Mus musculus)


name: [cypemycin](1-18)-L-Cys-L-Leu-L-Val-L-Cys + A => AH2 + C(3,19),S(21)-[cypemycin](1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide + CO2 + hydrogen sulfide


name: 1-aminocyclopropane-1-carboxylate + H2O <=> 2-oxobutanoate + NH4(+)


name: L-arginyl-[protein] + phosphate => H2O + N(omega)-phospho-L-arginyl-[protein]


name: O2 + 2 plastoquinol-9 => 2 H2O + 4 hnu + 2 plastoquinone-9


name: beta-D-galactosyl-(1<->1)-sphing-4-enine + H(+) + UDP => sphing-4-enine + UDP-alpha-D-galactose


name: (3Z)-hex-3-en-1-ol + benzoyl-CoA = (3Z)-hex-3-en-1-yl benzoate + CoA


name: AKT phosphorylates CBY1 (Rattus norvegicus)


name: 2-oxoglutarate + 8-hydroxysalvigenin + O2 <=> CO2 + formaldehyde + pilosin + succinate


name: H2O + N(8)-acetylspermidine = acetate + spermidine


name: (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase] => acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: SL (surrogate light chain) binds IgH to form pre-BCR (Homo sapiens)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Sus scrofa)


name: PGH2 is isomerised to PGD2 by HPGDS (Dictyostelium discoideum)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Canis familiaris)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Rattus norvegicus)


name: Factor D cleaves C3b-bound Factor B (Homo sapiens)


name: (2R,3S)-piscidate + (E)-sinapoyl-CoA <=> cimicifugate J + CoA


name: campesterol + D-glucose => campesteryl 3-beta-D-glucoside + H2O


name: CTNNBIP1 binds beta-catenin (Danio rerio)


name: Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Mus musculus)


name: AKT phosphorylates TSC2, inhibiting it (Dictyostelium discoideum)


name: CDK1 phosphorylates LBR (Rattus norvegicus)


name: 2,6-dimethylheptanoyl-CoA + H2O => 2,6-dimethylheptanoate + CoA + H(+)


name: BOD1L1 binds SET1A complex (Rattus norvegicus)


name: PP6 dephosphorylates SEC24 (Canis familiaris)


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Gallus gallus)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Autophosphorylation of insulin receptor (Bos taurus)


name: Binding of vRNP:M1:NEP complex to CRM1 export receptor (Homo sapiens)


name: Caspase-mediated cleavage of Etk (Bos taurus)


name: The phagophore extends from the PIP3-enriched structure (Schizosaccharomyces pombe)


name: diphosphate + pseudolaratriene => (2E,6E,10E)-geranylgeranyl diphosphate


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + taurohyocholate => O2 + reduced [NADPH--hemoprotein reductase] + taurochenodeoxycholate


name: PDE3B hydrolyses cAMP to AMP (Sus scrofa)


name: 2-hydroxy-2-methylpropanal + H2O + NAD(+) <=> 2-hydroxy-2-methylpropanoate + 2 H(+) + NADH


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Xenopus tropicalis)


name: ALDHs oxidise atRAL to atRA (Rattus norvegicus)


name: 4-methylsulfanyl-2-oxobutanoate + H(+) <=> 3-methylsulfanylpropanal + CO2


name: 2 Na(+)(out) + tauro-beta-muricholate(out) = 2 Na(+)(in) + tauro-beta-muricholate(in)


name: SARS virus buds into ERGIC lumen (Homo sapiens)


name: AMBRA1 binds DYNLL1,DYNLL2 (Homo sapiens)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Rattus norvegicus)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Canis familiaris)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Drosophila melanogaster)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Homo sapiens)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Mus musculus)


name: [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) => [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: PDK isozymes phosphorylate PDHC subunit E1 (Gallus gallus)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Danio rerio)


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Homo sapiens)


name: ADP + gamma-L-glutamyl-[BtrI ACP] + phosphate => ATP + holo-[BtrI ACP] + L-glutamate


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Homo sapiens)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Bos taurus)


name: brassicasterol + UDP-alpha-D-glucose <=> brassicasterol 3-beta-D-glucoside + H(+) + UDP


name: 5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Mus musculus)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Mus musculus)


name: H(+)(out) + L-asparagine(in) + Na(+)(in) => H(+)(in) + L-asparagine(out) + Na(+)(out)


name: glycyl-L-glutamine(out) + H(+)(out) = glycyl-L-glutamine(in) + H(+)(in)


name: Defective SLC17A5 does not cotransport Neu5Ac, H+ from lysosomal lumen to cytosol (Homo sapiens)


name: p-S446-IRF5 dimer translocates to the nucleus (Gallus gallus)


name: 5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate => 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine


name: (+)-alpha-tocopherol + H(+) + S-adenosyl-L-homocysteine => gamma-tocopherol + S-adenosyl-L-methionine


name: ribonucleotidyl-uridine-RNA <=> a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-uridine-RNA


name: 4-hydroxybenzoate + all-trans-octaprenyl diphosphate => 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate


name: p100:RELB binds active NIK:p-IKKA dimer (Homo sapiens)


name: alpha-L-arabinopyanose + NADP(+) <=> H(+) + L-arabinono-1,4-lactone + NADPH


name: 13-hydroxydocosanoate + UDP-alpha-D-glucose <=> 13-(beta-D-glucosyloxy)docosanoate + H(+) + UDP


name: 2xPDKX:2xZn2+ phosphorylates PDX (Xenopus tropicalis)


name: ATP + H(+) + NADPH + picolinate <=> AMP + diphosphate + NADP(+) + picolinal


name: PAK1-3 dimer disassociates (Drosophila melanogaster)


name: 2 (3,4-dimethoxyphenyl)methanol radical + 2 H2O => 2 (3,4-dimethoxyphenyl)methanol + H2O2


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Bos taurus)


name: Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking (Homo sapiens)


name: arginine + H2O => ornithine + urea [ARG2] (Homo sapiens)


name: RPA binds to the Flap (Plasmodium falciparum)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Sus scrofa)


name: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH


name: (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH => (1R,2S)-ephedrine + NAD(+)


name: Pol II mediated transcription of microRNA genes (Homo sapiens)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Homo sapiens)


name: H2O + substance P <=> Gly-L-Leu-L-Met-NH2 + substance P(1-8)


name: CTNNBIP1 binds beta-catenin (Homo sapiens)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Rattus norvegicus)


name: a (2E)-enoyl-CoA + H2O => a (3R)-3-hydroxyacyl-CoA


name: CHEK2 phosphorylates TTC5 (Rattus norvegicus)


name: acetaldehyde [cytosolic] => acetaldehyde [mitochondrial] (Homo sapiens)


name: H2O + nitrite + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + nitrate + 2 reduced [2Fe-2S]-[ferredoxin]


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Caenorhabditis elegans)


name: Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA (Danio rerio)


name: LIPs hydrolyze TG to DAG and LCFA (Homo sapiens)


name: Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Homo sapiens)


name: APBB1 and MAPK8 bind diphosphorylated H2AFX (Canis familiaris)


name: a ubiquinone + caffeine + H2O <=> 1,3,7-trimethylurate + a ubiquinol


name: (20S)-ginsenoside C-K + UDP-alpha-D-glucose = (20S)-ginsenoside F2 + H(+) + UDP


name: GMPS dimer transforms 6TXMP to 6TGMP (Plasmodium falciparum)


name: 3-oxo-(23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA + NADP(+)


name: 2-phenylethylamine + H2O + O2 <=> 2-phenylacetaldehyde + H2O2 + NH4(+)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Schizosaccharomyces pombe)


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Xenopus tropicalis)


name: Edg-7 lysophosphatidic acid receptor binding


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Drosophila melanogaster)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Plasmodium falciparum)


name: Iodide is taken up by thyroid epithelial cells (Sus scrofa)


name: 3,3'-diiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3,3'-diiodo-L-thyronine


name: CO2 + H2O + pentadecanal => (2R)-2-hydroperoxyhexadecanoate + H(+)


name: p-EPHB phosphorylates SDC2 (Rattus norvegicus)


name: (R)-carnitinyl-CoA + crotonobetaine => (R)-carnitine + crotonobetainyl-CoA


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Mus musculus)


name: H2O + N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] => H(+) + L-arginyl-[protein] + lactate


name: NADP(+) + xylitol = D-xylose + H(+) + NADPH


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Rattus norvegicus)


name: (9Z)-octadecenoate + O2 <=> (8R)-hydroperoxy-(9Z)-octadecenoate


name: Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Sus scrofa)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Dictyostelium discoideum)


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Rattus norvegicus)


name: 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + CO2 + S-adenosyl-L-methionine = 2 H(+) + S-adenosyl-L-homocysteine + wybutosine(37) in tRNA(Phe)


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane + H2O => GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: 7-oxocholesterol + H(+) + NADPH => 7alpha-hydroxycholesterol + NADP(+)


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Rattus norvegicus)


name: Activated FGFR1 binds SHC1 (Drosophila melanogaster)


name: PIAS4 SUMOylates PPARA with SUMO1 (Rattus norvegicus)


name: Emilin is found in elastic fibres (Homo sapiens)


name: acetyl-CoA + alpha-D-glucosamine 1-phosphate <=> CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate


name: arsenate(in) + H(+)(in) = arsenate(out) + H(+)(out)


name: (S)-benzodiazepinedione + dimethylallyl diphosphate => (2R,3S,11S)-aszonalenin + diphosphate


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)


name: SGTA binds mislocalized membrane protein (Mus musculus)


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Drosophila melanogaster)


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Gallus gallus)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Xenopus tropicalis)


name: PNPLA5 hydrolyzes TAG (Drosophila melanogaster)


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Rattus norvegicus)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] <=> 24-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (1S)-1-hydroxy-23-oxo-24,25,26,27-tetranorcalciol + 2 H2O + 2 oxidized [adrenodoxin] => (1S)-1,23-dihydroxy-24,25,26,27-tetranorcalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: FGFR1c binds to FGF (Caenorhabditis elegans)


name: avermitilol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: transforming growth factor beta receptor activity, type II


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> (-)-kolavenyl diphosphate


name: (S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) => ATP + H(+) + L-2-aminoadipate + NADPH


name: a 2'-deoxyribonucleoside + phosphate => a 2'-deoxyribonucleoside 5'-phosphate + H2O


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Bos taurus)


name: H(+) + keto-D-tagatose + NADH => D-altritol + NAD(+)


name: Activation of conventional Protein Kinase C (Caenorhabditis elegans)


name: arginine + H2O => ornithine + urea [ARG2] (Rattus norvegicus)


name: YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Rattus norvegicus)


name: D-ornithine + H2O + O2 <=> 5-amino-2-oxopentanoate + H2O2 + NH4(+)


name: acetyl-CoA + 5 H(+) + holo-[ACP] + 5 malonyl-CoA => 3,5,7,9,11-pentaoxododecanoyl-[ACP] + 5 CO2 + 6 CoA


name: a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: CoA + H(+) + piperyline => (E,E)-piperoyl-CoA + pyrrolidine


name: TGFBR3 complex binds to TGFBR2 (Bos taurus)


name: FLIP(S) and procaspase-8 form heterodimer (Mus musculus)


name: (2E)-geranyl diphosphate + H2O <=> (R)-alpha-terpineol + diphosphate


name: L-serine(in) + Na(+)(in) = L-serine(out) + Na(+)(out)


name: H2O + N-methyl-2-methylpropanamine + NAD(+) = 2-methylpropanal + H(+) + methylamine + NADH


name: Phosphorylated ERF translocates to the cytosol (Danio rerio)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-alanine + O2 <=> (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2


name: VEGFA-165 dimer binds VEGFR2 dimer (Sus scrofa)


name: butanal + CoA + NAD(+) => butanoyl-CoA + H(+) + NADH


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR (Sus scrofa)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Dictyostelium discoideum)


name: (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: phosphate + sphinganine => H2O + sphinganine 1-phosphate


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Canis familiaris)


name: Activated FGFR3 binds PLCG1 (Danio rerio)


name: 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) <=> 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 3-hydroxy-L-phenylalanine => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2


name: digitoxin + 2 Fe(II)-[cytochrome c] + 3 H(+) = dihydrodigitoxin + 2 Fe(III)-[cytochrome c]


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: K63-linked polyubiquitin modification-dependent protein binding


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Gallus gallus)


name: ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Mus musculus)


name: IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Homo sapiens)


name: ISGylation of host protein filamin B (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+)


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Homo sapiens)


name: (2R,3S)-piscidate + (E)-sinapoyl-CoA => cimicifugate J + CoA


name: STAT binds to the active receptor (Canis familiaris)


name: GNB2L1 binds IKKA:IKKB:NEMO (Rattus norvegicus)


name: 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + CO2 + CoA => (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + H(+) + malonyl-CoA


name: ARL2:GTP:ARL2BP binds SLC25A4 (Mus musculus)


name: L-aspartate(in) + L-phenylalanine(out) <=> L-aspartate(out) + L-phenylalanine(in)


name: H2O + triacetin => acetate + diacetylglycerol + H(+)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-mannitol + NAD(+) => D-mannose + H(+) + NADH


name: RBKS phosphorylates ribose to R5P (Homo sapiens)


name: CD320 binds extracellular TCN2:RCbl (Homo sapiens)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Schizosaccharomyces pombe)


name: TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III (Canis familiaris)


name: peregrinol diphosphate <=> (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: arsenite(in) + ATP + H2O => ADP + arsenite(out) + H(+) + phosphate


name: albendazole + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + hydroxyalbendazole + oxidized [NADPH--hemoprotein reductase]


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Sus scrofa)


name: (R)-pantoate + ATP + beta-alanine <=> (R)-pantothenate + ADP + H(+) + phosphate


name: L-cysteine(out) + L-methionine(in) = L-cysteine(in) + L-methionine(out)


name: H2O + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose <=> lactose + N-acetylneuraminate


name: Salvage - Sepiapterin is reduced to BH2 (Dictyostelium discoideum)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Canis familiaris)


name: SLC35D2 exchanges UDP-D-glucose for UMP (Gallus gallus)


name: 2 ATP + benzoate + L-phenylalanine + N-benzoyl-L-phenylalaninol <=> 2 AMP + asperphenamate + 2 diphosphate + H(+)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Canis familiaris)


name: a cytidine in tRNA + S-adenosyl-L-methionine => a 5-methylcytidine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: Dimerization of phosphorylated IRF3/IRF7 (Xenopus tropicalis)


name: AMOT proteins bind YAP1 (Xenopus tropicalis)


name: dATP + H2O = 2'-deoxyadenosine + H(+) + triphosphate


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphate + H(+) + NADPH => 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphate + NADP(+)


name: COMT transfers Met to DA to form 3MT (Mus musculus)


name: PTPN11 binds p-Y759-IL6ST (Homo sapiens)


name: (3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2 => N-methyl-L-dopa + O2


name: peonidin + UDP-alpha-D-glucose => peonidin 3-O-beta-D-glucoside + UDP


name: 15-cis-phytoene + 5 A => 5 AH2 + all-trans-3,4-didehydrolycopene


name: NPC2 transfers CHOL to NPC1 (Drosophila melanogaster)


name: (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 = (E)-2,4-dihydroxycinnamoyl-CoA + CO2 + succinate


name: 5-aminopentanoate + acetyl-CoA + 20 H(+) + 8 malonyl-CoA + 13 NADPH => 8 CO2 + 9 CoA + 7 H2O + 13 NADP(+) + wortmanamide B


name: Expression of HSP90B1 (Dictyostelium discoideum)


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Sus scrofa)


name: G-protein gated monoatomic ion channel activity


name: Interaction of BCL10:MALT1 with CARMA1 to form CBM complex (Homo sapiens)


name: TRIM27 polyubiquitinates PTEN (Sus scrofa)


name: DCC interacts with DIP13alpha (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-ethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose => alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: IL3 stimulation induces Vav binding to Tec kinase (Homo sapiens)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL (Homo sapiens)


name: nucleotide transmembrane transporter activity


name: 5-deoxystrigol ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one => 5-deoxystrigol + H2O


name: fumarate(out) + 2 H(+)(out) => fumarate(in) + 2 H(+)(in)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Homo sapiens)


name: mycinamicin III + S-adenosyl-L-methionine = H(+) + mycinamicin IV + S-adenosyl-L-homocysteine


name: 3-(uracil-1-yl)-L-alanine + acetate + H(+) => O-acetyl-L-serine + uracil


name: 2-oxoglutarate + asnovolin A + 2 O2 => CO2 + fumigatonoid A + succinate


name: ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2 => ergosterol + 2 H2O + NADP(+)


name: H2O + L-prolinylglycine <=> glycine + L-proline


name: Endocytosis of Ca impermeable AMPA receptors (Mus musculus)


name: 8-oxoguanine + H(+) + H2O <=> NH4(+) + urate


name: 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + ATP + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin] => 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + ADP + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate


name: LIPC dimer hydrolyses TAG to DAG and FA (Bos taurus)


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Canis familiaris)


name: PIAS2-2 SUMOylates THRA with SUMO1 (Rattus norvegicus)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Bos taurus)


name: AP-2 directly binds some endocytic cargo (Saccharomyces cerevisiae)


name: (2E)-dodecenoyl-CoA + H2O <=> (2E)-dodecenoate + CoA + H(+)


name: S-Farn-Me KRAS4B binds calmodulin (Bos taurus)


name: Damaged dsDNA becomes damaged DNA template (Homo sapiens)


name: ADP + H(+) + O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] => ATP + L-seryl-[pyruvate dehydrogenase E1 alpha subunit]