name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Sus scrofa)


name: (2E)-hexadecenedioyl-CoA + H2O <=> (3R)-hydroxyhexadecanedioyl-CoA


name: 26-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 26-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Xenopus tropicalis)


name: FarC-PTP4A2 binds RABGGTB (Rattus norvegicus)


name: USP10 deubiquitinates SNX3, CFTR (Sus scrofa)


name: H(+) + indolmycin + S-adenosyl-L-homocysteine => N-demethylindolmycin + S-adenosyl-L-methionine


name: cAMP activates EPAC1 (Schizosaccharomyces pombe)


name: Inactivation of Rho-GTP by p190RhoGAP (Danio rerio)


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Sus scrofa)


name: RHOD translocates to the Golgi membrane (Homo sapiens)


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Homo sapiens)


name: (1S,5S)-alpha-pinene + diphosphate => (2E)-geranyl diphosphate


name: Active MTORC1 phosphorylates ULK1 (Sus scrofa)


name: 2-oxoglutarate + heptyl sulfate + O2 => CO2 + H(+) + heptanal + succinate + sulfate


name: ATP + pseudouridine => ADP + H(+) + psi-UMP


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Danio rerio)


name: RHOG binds effectors at the ER membrane (Homo sapiens)


name: FUT2 transfers Fuc to LeX to form LeY (Canis familiaris)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Xenopus tropicalis)


name: Vamp7 associated Lysosome to Plasma membrane transport (Dictyostelium discoideum)


name: CPO transforms COPRO3 to PPGEN9 (Mus musculus)


name: (S)-ureidoglycolate <=> glyoxylate + urea


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Mus musculus)


name: all-trans-beta-carotene + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => all-trans-zeaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Xenopus tropicalis)


name: CYP7A1 7-hydroxylates CHOL (Xenopus tropicalis)


name: myo-inositol + UDP-alpha-D-galactose = alpha-D-galactosyl-(1->3)-1D-myo-inositol + H(+) + UDP


name: Carbonic anhydrase hydrates carbon dioxide (cytosol) (Rattus norvegicus)


name: 6alpha-hydroxytyphasterol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + typhasterol


name: cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + cholesterol


name: 3'-dehydrocarminate + H(+) => 1,5-anhydro-D-erythro-hex-1-en-3-ulose + kermesate


name: a D-aminoacyl-tRNA + H2O <=> a D-alpha-amino acid + a tRNA + H(+)


name: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a 3-oxo-Delta(4)-steroid + H(+) + NADPH => a 3-oxo-5alpha-steroid + NADP(+)


name: RHOG GAPs stimulate RHOG GTPase activity (Drosophila melanogaster)


name: CDH19 gene expression is stimulated by SOX10 (Homo sapiens)


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Sus scrofa)


name: TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Homo sapiens)


name: HDAC10 deacetylates histone (Danio rerio)


name: 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate <=> CO2 + deoxyviolacein + 2 H2O + NAD(+)


name: A + a (4R,8E)-4-hydroxysphingenine ceramide + 2 H2O => AH2 + an N-acyl-(4R)-4-hydroxysphinganine + O2


name: H2O + N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine = 4-amino-5-aminomethyl-2-methylpyrimidine + formate


name: G-protein subunits dissociate from WNT:FZD complex (Homo sapiens)


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Rattus norvegicus)


name: dUTP(in) + UTP(out) => dUTP(out) + UTP(in)


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(8),N'(8)-citryl-bis(spermidine) => H(+) + holo-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine)


name: 2 Fe(III)-[cytochrome] + H2O + nitrite => 2 Fe(II)-[cytochrome] + 2 H(+) + nitrate


name: RDH12 reduces atRAL to atROL (Mus musculus)


name: brevianamide F + dimethylallyl diphosphate <=> diphosphate + tryprostatin B


name: PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Rattus norvegicus)


name: (11Z)-octadecenoyl-CoA + H2O <=> (11Z)-octadecenoate + CoA + H(+)


name: 2 5'-deoxyadenosine + A + a macrocyclic archaeaol phospholipid + 2 H(+) + 2 L-methionine => a 2,3-di-O-phytanyl-sn-glycerophospholipid + AH2 + 2 S-adenosyl-L-methionine


name: 5,6-dihydrouracil + NAD(+) = H(+) + NADH + uracil


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Rattus norvegicus)


name: 1-butyrylglycerol + H2O <=> butanoate + glycerol + H(+)


name: thromboxane B2(out) = thromboxane B2(in)


name: 2-methylbutan-1-ol + hexanoyl-CoA <=> 2-methylbutyl hexanoate + CoA


name: UMPS dimer decarboxylates OMP to UMP (Dictyostelium discoideum)


name: Translocation of PMAIP1 (NOXA) to mitochondria (Gallus gallus)


name: Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Activation of JAK kinases (Rattus norvegicus)


name: ISGylation of protein phosphatase 1 beta (PP2CB) (Drosophila melanogaster)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Canis familiaris)


name: PIP3 recruits AKT to the membrane (Danio rerio)


name: 3-methyl-L-tyrosine + H2O2 => 5-hydroxy-3-methyl-L-tyrosine + H2O


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Mus musculus)


name: D-sorbopyranose + H2O2 => D-sorbitol + O2


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Gallus gallus)


name: Opioid receptors bind opioid peptides (Danio rerio)


name: AH2 + all-trans-4,4'-diapolycopen-4-oate + H(+) => A + all-trans-4,4'-diapolycopen-4-al + H2O


name: SLC46A1 transports FOLA from extracellular region to cytosol (Homo sapiens)


name: Clathrin recruits PIK3C2A (Homo sapiens)


name: acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] => malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]


name: ATP Hydrolysis By Myosin (Canis familiaris)


name: Aggresome dissociates from dynein and microtubule (Xenopus tropicalis)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 => (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate


name: 1,2-diacyl-sn-glycero-3-phospho-N-acyl-L-serine + H2O <=> 1-acyl-sn-glycero-3-phospho-N-acyl-L-serine + a fatty acid + H(+)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Homo sapiens)


name: glycyl-L-lysine(out) + 2 H(+)(out) => glycyl-L-lysine(in) + 2 H(+)(in)


name: (3E)-3,4-didehydrorhodopin + AH2 => A + rhodopin


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: 5'-dehydroadenosine + H2O + O2 <=> 9-riburonosyladenine + H(+) + H2O2


name: Aquaporins passively transport water into cells (Canis familiaris)


name: Ras:GTP binds p120-RasGAP (Gallus gallus)


name: H2O + N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine => H(+) + L-aspartate + N-acetyl-beta-D-glucosaminylamine


name: Protein 4.1 binds CASK (Caenorhabditis elegans)


name: 3-aminoavenalumate + ATP + H(+) + nitrite <=> 3-diazoavenalumate + AMP + diphosphate + H2O


name: 4beta-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: NUAK1 phosphorylates TP53 (Canis familiaris)


name: A + H2O + N(6),N(6)-dimethyl-L-lysyl-[protein] => AH2 + formaldehyde + N(6)-methyl-L-lysyl-[protein]


name: ATP + CoA + dodecanoate <=> AMP + diphosphate + dodecanoyl-CoA


name: an aliphatic aldoxime => a nitrile + H2O


name: Autocatalytic phosphorylation of FGFR1c (Homo sapiens)


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + H(+) + H2O = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + N-(2,3-dihydroxybenzoyl)-L-serine


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Canis familiaris)


name: L-lactate dehydrogenase (cytochrome) activity


name: 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-octadecanoylglycerol + H(+)


name: 4-O-beta-D-glucosyl-vanillin + acetate => 3-hydroxy-3-(4-O-beta-D-glucosyl-3-methoxyphenyl)propanoate


name: 1-carboxyvinyl carboxyphosphonate + H(+) <=> 3-(hydrohydroxyphosphoryl)pyruvate + CO2


name: ATP + hydrogencarbonate <=> ADP + carboxyphosphate


name: IDUA hydrolyses Heparan sulfate chain(1) (Xenopus tropicalis)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Rattus norvegicus)


name: CREB3L3 translocates from the cytosol to the nucleus (Homo sapiens)


name: dibenzofuran + H(+) + NADH + O2 <=> biphenyl-2,2',3-triol + NAD(+)


name: SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Canis familiaris)


name: 2 H2O2 + Reactive Blue 5 <=> 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + 2 H(+) + 2 H2O + phthalate


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Homo sapiens)


name: LONP1 binds mitochondrial matrix proteins (Dictyostelium discoideum)


name: [calmodulin]-L-lysine + S-adenosyl-L-methionine <=> [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine


name: p-Y420-FYN is phosphorylated on S21 (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (13E)-labda-7,13-dien-15-yl diphosphate


name: glycine + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + sarcosine


name: Dephosphorylation of TYK2 by PTP1B (Gallus gallus)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,4,5,6-tetrakisphosphate + phosphate


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Bos taurus)


name: PI3K binds to p-6Y-SYK (Rattus norvegicus)


name: ATXN3 family cleave Ub chains (Canis familiaris)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Sus scrofa)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a prenal + H2O2 + L-cysteine => an S-prenyl-L-cysteine + H2O + O2


name: Phosphorylated GAB1 recruits PI3K to MET (Caenorhabditis elegans)


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Danio rerio)


name: a fatty acyl-CoA + H2O = a fatty acid + CoA + H(+)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)


name: ATM phosphorylates RBBP8 (Canis familiaris)


name: PIAS1 SUMOylates THRB with SUMO3 (Mus musculus)


name: "plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)"


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Danio rerio)


name: ULK1 is dephosphorylated (Gallus gallus)


name: Association of  PARVA with TESK1 (Drosophila melanogaster)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 2beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + tetrathionate => H(+) + sulfate + sulfur + thiosulfate


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine + ethanolamine


name: 9,9',15-tri-cis-zeta-carotene + plastoquinol-9 => 15,9'-di-cis-phytofluene + plastoquinone-9


name: chorismate = 3-hydroxybenzoate + pyruvate


name: L-glutamine(in) + L-threonine(out) + Na(+)(out) <=> L-glutamine(out) + L-threonine(in) + Na(+)(in)


name: holo-[peptidyl-carrier protein] + L-tryptophyl-5'-AMP => AMP + L-tryptophyl-[peptidyl-carrier protein]


name: benzoyl cyanide + H2O2 => (R)-mandelonitrile + O2


name: AKT phosphorylates KAT6A (Dictyostelium discoideum)


name: TRPM5 transports Na+ from the extracellular region to the cytosol (Homo sapiens)


name: (R)-4-phosphopantoate + ATP + beta-alanine => (R)-4'-phosphopantothenate + AMP + diphosphate + H(+)


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Rattus norvegicus)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NAD(+) => 12alpha-hydroxy-3-oxochola-4-en-24-oate + H(+) + NADH


name: (9Z,12Z)-octadecadienoyl-CoA + 1-O-hexadecyl-2-acetyl-sn-glycerol = 1-O-hexadecyl-2-acetyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + CoA


name: 5alpha-cholestan-3-one + NADP(+) => cholest-4-en-3-one + H(+) + NADPH


name: (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA + H(+) + NADPH => (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + NADP(+)


name: [G-protein-coupled receptor] + ATP => [G-protein-coupled receptor]-phosphate + ADP + H(+)


name: 2Fe-2S is inserted in UQCRFS1 (Schizosaccharomyces pombe)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) (Gallus gallus)


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Dictyostelium discoideum)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Danio rerio)


name: POLZ elongates POLI-incorporated dNMP (Canis familiaris)


name: 3,3',5-triiodo-L-thyronine(out) + L-glutamate(in) => 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out)


name: NOTCH1 gene transcription (Homo sapiens)


name: ATP + N-acetyl-D-glucosamine => ADP + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol <=> a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: LDH tetramer reduces PYR to LACT (Rattus norvegicus)


name: D-nopaline + H2O + NADP(+) <=> 2-oxoglutarate + H(+) + L-arginine + NADPH


name: intracellularly ligand-gated monoatomic ion channel activity


name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Sus scrofa)


name: p-S MAPK6,4 binds MAPKAPK5 (Homo sapiens)


name: 5-diphosphoinositol pentakisphosphate 4-kinase activity


name: 26S proteasome degrades HIFalpha (Bos taurus)


name: PLK3 phosphorylates CDC25C (Schizosaccharomyces pombe)


name: 5alpha,6beta,17alpha-trihydroxywithanolide 27-O-beta-D-glucoside + H(+) + UDP => 5alpha,6beta,17alpha,27-tetrahydroxywithanolide + UDP-alpha-D-glucose


name: PGM2:Mg2+ isomerises R1P to R5P (Caenorhabditis elegans)


name: Initial activation of proMMP7 by trypsin (Gallus gallus)


name: Receptor CCR6 binds CCL20 ligand (Rattus norvegicus)


name: atREs binds to nascent CM (Canis familiaris)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Rattus norvegicus)


name: NTRK3(496-641) binds NELFB (Homo sapiens)


name: CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 (Mus musculus)


name: ADCY3:GNAL:GTP converts ATP to cAMP (Homo sapiens)


name: N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine


name: GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP (Canis familiaris)


name: type 2 vasoactive intestinal polypeptide receptor binding


name: Exocytosis of tertiary granule lumen proteins (Plasmodium falciparum)


name: FAD + H(+) + trans,octa-cis-decaprenylphospho-beta-D-ribofuranose => FADH2 + trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose


name: 2-dehydro-3-deoxy-L-arabinonate <=> glycolaldehyde + pyruvate


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: galactitol(out) + N(pros)-phospho-L-histidyl-[protein] <=> galactitol 1-phosphate(in) + L-histidyl-[protein]


name: NTPDase3 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: 2 Fe(III)-[cytochrome c] + hydrogen sulfide = 2 Fe(II)-[cytochrome c] + H(+) + sulfur


name: "sulfide-cytochrome-c reductase (flavocytochrome c)"


name: "Hydron translocation linked to the hydrolysis of a nucleoside triphosphate"


name: FAHD1 dimer hydrolyses OA to PYR (Homo sapiens)


name: 5alpha-androstan-3,17-dione + A <=> 5alpha-androst-1-ene-3,17-dione + AH2


name: H(+) + H2O + nogalonate => deoxynogalonate + O2


name: LC3:ATG7 dimer binds ATG3 (Mus musculus)


name: POLZ extends translesion synthesis (Xenopus tropicalis)


name: pseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-homocysteine


name: mito-STARD7 transports Q10 to outer mitochondrial membrane (Bos taurus)


name: CBL monoubiquitinates activated MET (Caenorhabditis elegans)


name: (2S)-ethylmalonyl-CoA + NADP(+) => (2E)-butenoyl-CoA + CO2 + NADPH


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Mus musculus)


name: 4-methylumbelliferone sulfate(out) + ADP + H(+) + phosphate => 4-methylumbelliferone sulfate(in) + ATP + H2O


name: (E,E)-piperoyl-AMP + diphosphate => (E,E)-piperate + ATP + H(+)


name: glyoxylate + urea => (S)-ureidoglycolate


name: 3-carboxy-cis,cis-muconate + H(+) => 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Homo sapiens)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Gallus gallus)


name: Interaction of integrin alphaVbeta3 with Fibrillin (Mus musculus)


name: 2-oxoglutarate + 6-acetamido-3-aminohexanoate = 6-acetamido-3-oxohexanoate + L-glutamate


name: SDHAF4 binds to FAD-SDHA (Caenorhabditis elegans)


name: 3-(2,4-dioxopentyl)-2,3,6,8,9-pentahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+) => 3-(2,4-dioxopentyl)-3,6,8,9-tetrahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2


name: WNT ligands traffic to the Golgi (Drosophila melanogaster)


name: MIB2 binds CFLAR (Drosophila melanogaster)


name: sodium-dependent multivitamin transmembrane transporter activity


name: 5-phospho-L-arabinonate + H(+) => H2O + L-arabino-1,4-lactone 5-phosphate


name: H2O + trihexadecanoylglycerol = 2,3-dihexadecanoyl-sn-glycerol + H(+) + hexadecanoate


name: BRCA1:BARD1 heterodimer autoubiquitinates (Homo sapiens)


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Rattus norvegicus)


name: deaminated base DNA N-glycosylase activity


name: ATP + CoA + isophthalate => AMP + diphosphate + isophthalyl-CoA


name: alpha-Kdo-(2->6)-lipid IVA (E. coli) + ATP = 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA (E. coli) + ADP + H(+)


name: UGT1A6 glucuronates ST (Rattus norvegicus)


name: RHOB GEFs activate RHOB (Xenopus tropicalis)


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Homo sapiens)


name: Complement factor I binds to extracellular Factor H:C3b (Xenopus tropicalis)


name: [eIF5A protein]-L-lysine + spermidine <=> [eIF5A protein]-deoxyhypusine + propane-1,3-diamine


name: Unknown enzyme(s) process 4-HMA to 4-Hbz (Homo sapiens)


name: Aquaporins passively transport water into cells (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O


name: 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [NAD(+)] activity


name: Elastin degradation by MMP14 (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphoethanolamine = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Canis familiaris)


name: 5-HT2 receptor can bind serotonin (Rattus norvegicus)


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Caenorhabditis elegans)


name: 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + 2 succinate => 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 O2


name: PKR binds activating host RNA (Canis familiaris)


name: demethylsuberosin + O2 + reduced [NADPH--hemoprotein reductase] => (7S)-marmesin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: factor VII -> factor VIIa (Mus musculus)


name: Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes (Drosophila melanogaster)


name: 17alpha-estradiol + UDP-alpha-D-glucuronate <=> 17alpha-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: D-glucose + phosphate => alpha-D-glucose 1-phosphate + H2O


name: D-serine(in) + Na(+)(in) <=> D-serine(out) + Na(+)(out)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Rattus norvegicus)


name: SENP1,2,5 proteolytically process SUMO3 (Rattus norvegicus)


name: H2O + malonyl-CoA = adenosine 3',5'-bisphosphate + 2 H(+) + malonyl-4'-phosphopantetheine


name: C-ter TLR9 dimer binds HCQ (Homo sapiens)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Rattus norvegicus)


name: Dopa is decarboxylated to dopamine (Xenopus tropicalis)


name: CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Sus scrofa)


name: NADP(+) + octadecan-1-ol <=> H(+) + NADPH + octadecanal


name: Type XII and XIV collagens associate with type I and type II fibrils. (Rattus norvegicus)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Sus scrofa)


name: (R)-octopamine => (4-hydroxyphenyl)acetaldehyde + NH4(+)


name: 3beta,7alpha-dihydroxyandrost-5-en-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3beta-hydroxyandrost-5-en-17-one + O2 + reduced [NADPH--hemoprotein reductase]


name: 3-linalylflaviolin + diphosphate => (2E)-geranyl diphosphate + flaviolin


name: FGFRL1 dimer binds FGFs (Rattus norvegicus)


name: TRIF:activated TLR3/TLR4 complex recruits RIP1 (Gallus gallus)


name: CHMP7 binds LEMD2 (Saccharomyces cerevisiae)


name: acetyl-CoA + an S-substituted L-cysteine = an N-acetyl-L-cysteine-S-conjugate + CoA + H(+)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Drosophila melanogaster)


name: Homocysteine is degraded to oxobutanoate and H2S (Rattus norvegicus)


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Rattus norvegicus)


name: Phosphorylation of BIM by JNK (Bos taurus)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Plasmodium falciparum)


name: SLCO3A1 isoform 1 has abroad substrate specificity (Homo sapiens)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Canis familiaris)


name: H(+) + NADPH + selenodiglutathione <=> glutathione + glutathioselenol + NADP(+)


name: lipoate transmembrane transporter activity


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Mus musculus)


name: PI is exchanged with PC by PITPNB (Plasmodium falciparum)


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)


name: AKT phosphorylates FOXO transcription factors (Drosophila melanogaster)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Canis familiaris)


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: 2'-deoxycytidine + phosphate => dCMP + H2O


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Drosophila melanogaster)


name: H(+) + NADH + propanal => 1-propanol + NAD(+)


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Sus scrofa)


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Homo sapiens)


name: 3-oxosphinganine + octadecanoyl-CoA => CoA + H(+) + N-octadecanoyl-3-oxosphinganine


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + firefly D-luciferin = adenosine 3',5'-bisphosphate + firefly D-sulfoluciferin + H(+)


name: Recruitment of POLB to the AP site (Bos taurus)


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Rattus norvegicus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: H2O + N-hexadecanoylethanolamine <=> ethanolamine + hexadecanoate


name: (3S)-hydroxydecanoyl-CoA <=> (2E)-decenoyl-CoA + H2O


name: (S)-3-methyl-2-oxopentanoate + L-glutamate => 2-oxoglutarate + L-isoleucine


name: ITPA dimer dephosphorylates RBV-TP to RBV-MP (Danio rerio)


name: Interaction of NUMB with L1 (Homo sapiens)


name: Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB (Homo sapiens)


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Drosophila melanogaster)


name: Expression of ID4 in the nephric duct (Homo sapiens)


name: Exocytosis of specific granule lumen proteins (Saccharomyces cerevisiae)


name: Latent TGF-beta-1 is cleaved by FURIN (Homo sapiens)


name: 3-hydroxybenzoyl-CoA + H2O + NADP(+) => benzoyl-CoA + H(+) + NADPH + O2


name: allocholate + allodeoxycholoyl-CoA = allocholoyl-CoA + allodeoxycholate


name: 1-dehydro-L-sorbose + AH2 => A + L-sorbopyranose


name: PIAS1 SUMOylates SATB1 with SUMO2,3 (Homo sapiens)


name: H2O + L-cysteinylglycine => glycine + L-cysteine


name: O2 + protopine + reduced [NADPH--hemoprotein reductase] = 6-hydroxyprotopine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Canis familiaris)


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)


name: CDKN1A gene transcription is stimulated by FOXO1,FOXO3,FOXO4 (Homo sapiens)


name: E2F6:TFDP1 binds to MGA:MAX (Sus scrofa)


name: an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose <=> an alpha-D-mannosylinositol-1-phosphodihydroceramide + GDP + H(+)


name: Formation of collagen fibres (Danio rerio)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + H(+) + S-adenosyl-L-homocysteine


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Homo sapiens)


name: ent-kaur-16-ene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> ent-kaur-16-en-19-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a sphingoid base + an ultra-long-chain fatty acyl-CoA <=> an N-(ultra-long-chain-acyl)-sphingoid base + CoA + H(+)


name: CYP3A4 oxidizes PREDN,PREDL (Canis familiaris)


name: GTP + H2O <=> guanosine + H(+) + triphosphate


name: 4-pyridoxolactone + H2O => 4-pyridoxate + H(+)


name: Translocation of PDK1 to Plasma membrane (Danio rerio)


name: PGM1:Mg2+ isomerises G1P to G6P (Rattus norvegicus)


name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Rattus norvegicus)


name: cytidine(72) in tRNA + S-adenosyl-L-methionine => 5-methylcytidine(72) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: Activated FGFR4 binds PLCG1 (Rattus norvegicus)


name: L-alanine + L-leucine => H2O + L-alanyl-L-leucine


name: PDK isozymes phosphorylate PDHC subunit E1 (Canis familiaris)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Gallus gallus)


name: ADA catalyzes the deamination of (deoxy)adenosine (Homo sapiens)


name: AH2 + O2 + progesterone <=> A + H2O + testosterone acetate


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) (Xenopus tropicalis)


name: STAT1,STAT3 binds PKR (Caenorhabditis elegans)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O <=> 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)


name: NTPDase7 hydrolyzes nucleoside triphosphates (Caenorhabditis elegans)


name: [sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + S-adenosyl-L-methionine <=> 2-thio-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + H(+) + L-methionine


name: a phytoceramide + 2 Fe(III)-[cytochrome b5] + H2O => a dihydroceramide + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: POM121 and NDC1 bind the Nup93 complex (Gallus gallus)


name: DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function (Rattus norvegicus)


name: NF1 is degraded by the proteasome (Mus musculus)


name: neryl diphosphate => beta-phellandrene + diphosphate


name: 1-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + CoA => (9Z)-octadecenoyl-CoA + 3-octadecanoyl-sn-glycerol


name: A + D-gluconate => 2-dehydro-D-gluconate + AH2


name: 3-oxohexanoyl-CoA + H(+) + NADH => (3R)-hydroxyhexanoyl-CoA + NAD(+)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Caenorhabditis elegans)


name: (R)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + salutaridine


name: [DsrC protein]-dithiol + 2 a quinone + 2 H(+) + hydrogen sulfide => [DsrC protein]-trisulfide + 2 a quinol + H(+)


name: acetate(out) + H(+)(out) => acetate(in) + H(+)(in)


name: Formation of anchoring fibrils (Homo sapiens)


name: aculene A + holo-[peptidyl-carrier protein] => aculene C + L-prolyl-[peptidyl-carrier protein]


name: Caspase-8 and FLIP(L) processing at TNFR signaling complex (Sus scrofa)


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Drosophila melanogaster)


name: 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine <=> 4',7-dihydroxy-3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: glutathione + prostaglandin A2 => prostaglandin A2-S-(S)-glutathione


name: Calmodulin dissociates KRAS4B from the plasma membrane (Bos taurus)


name: ULK1 is dephosphorylated (Drosophila melanogaster)


name: L-isoleucine transmembrane transporter activity


name: NCOA1 binds ESR1:estrogen:TGFA gene (Mus musculus)


name: Ferriheme is transferred from Albumin to Hemopexin (Homo sapiens)


name: CHDH oxidises Cho to BETALD (Drosophila melanogaster)


name: TRiC/CCT binds unfolded G-protein beta subunit (Gallus gallus)


name: p-T68-CHEK2 autophosphorylates (Rattus norvegicus)


name: Activated FMNL3 binds G-actin (Mus musculus)


name: (2E)-geranyl diphosphate + H2O = 4-terpineol + diphosphate


name: sGC stimulators bind sGC:NO (Rattus norvegicus)


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Sus scrofa)


name: CYP26A1,B1 4-hydroxylate atRA (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate => diphosphate + selina-4(15),7(11)-diene


name: Formation of FACT complex (Mus musculus)


name: TRiC/CCT binds unfolded G-protein beta subunit (Homo sapiens)


name: A + gibberellin A12 aldehyde + H2O => AH2 + gibberellin A12 + H(+)


name: 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Mus musculus)


name: Autocatalytic phosphorylation of FGFR4 (Rattus norvegicus)


name: Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Mus musculus)


name: 2 Na(+)(in) + pyruvate(in) => 2 Na(+)(out) + pyruvate(out)


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Danio rerio)


name: phosphoenolpyruvate [mitochondrial matrix] + citrate [cytosol] <=> phosphoenolpyruvate [cytosol] + citrate [mitochondrial matrix] (Gallus gallus)


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Caenorhabditis elegans)


name: GLUT7 and GLUT11 transport glucose and fructose (Saccharomyces cerevisiae)


name: DAG stimulates protein kinase C-delta (Danio rerio)


name: SFN dimer binds CDK1 and CCNB1 (Danio rerio)


name: ABCB4 transports PC from plasma membrane to extracellular region (Sus scrofa)


name: Phosphorylation of GAB2 by SFKs (Rattus norvegicus)


name: mycophenolate + UDP-alpha-D-glucuronate <=> H(+) + mycophenolate 7-O-beta-D-glucuronide + UDP


name: 4-hydroxyprotoasukamycin + H(+) + NADH + O2 => asukamycin + H2O + NAD(+)


name: H2O + L-fucono-1,4-lactone = H(+) + L-fuconate


name: phloretin + UDP-alpha-D-glucose => H(+) + phlorizin + UDP


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Rattus norvegicus)


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Sus scrofa)


name: 1-phenyl-1,2-propanedione + H(+) + NADH => (S)-phenylacetylcarbinol + NAD(+)


name: Corticosteroids bind to CBG in blood (Rattus norvegicus)


name: Detection of damage during initiation of DNA synthesis in S-phase (Caenorhabditis elegans)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: SLC6A3 binds DRIs (Caenorhabditis elegans)


name: ADIPOQ trimer binds ADIPOR dimers (Canis familiaris)


name: BMP2 binds to the receptor complex (Xenopus tropicalis)


name: adenosine(58) in tRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine


name: ADP + Ag(+)(out) + H(+) + phosphate => Ag(+)(in) + ATP + H2O


name: AP-1 stimulates IL1A transcription (Homo sapiens)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphoserine


name: a guanosine in RNA + H(+) + lactate => an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O


name: (4-hydroxyphenyl)acetaldehyde + H2O + NAD(+) <=> 4-hydroxyphenylacetate + 2 H(+) + NADH


name: glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]


name: PLOD3 binds Lysyl hydroxylated collagen propeptides (Canis familiaris)


name: 5-methylthiopropyl glucosinolate S-oxygenase activity


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Sus scrofa)


name: aurachin C epoxide + H2O + NADP(+) => aurachin C + H(+) + NADPH + O2


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Schizosaccharomyces pombe)


name: LIPs hydrolyze TG to DAG and LCFA (Rattus norvegicus)


name: Association of INK4 family proteins with CDK4/6 (Rattus norvegicus)


name: 5alpha-dihydrotestosterone 17-O-[beta-D-glucuronosyl-(1->2)-glucuronate] + H(+) + UDP => 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + UDP-alpha-D-glucuronate


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NADP(+)


name: 4beta-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-4beta,26-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: GPI-mannose ethanolamine phosphate phosphodiesterase activity


name: apulose 4-phosphate + D-glyceraldehyde 3-phosphate = D-xylulose 5-phosphate + dihydroxyacetone phosphate


name: SUMOyation of DNMT1 with SUMO1 (Xenopus tropicalis)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Canis familiaris)


name: Activated MET recruits GRB2-1:SOS1 (Xenopus tropicalis)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Homo sapiens)


name: (E)-sinapaldehyde + UDP-alpha-D-glucose <=> 4-O-(beta-D-glucosyl)-4-trans-sinapoyl aldehyde + H(+) + UDP


name: carnosine(out) + 2 H(+)(out) => carnosine(in) + 2 H(+)(in)


name: 3-methoxytyramine + H(+) + S-adenosyl-L-homocysteine => dopamine + S-adenosyl-L-methionine


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Xenopus tropicalis)


name: RHOA GEFs activate RHOA (Canis familiaris)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Xenopus tropicalis)


name: acetate + oxalyl-CoA => acetyl-CoA + oxalate


name: PRKN binds p-S-Ub:MOM proteins (Plasmodium falciparum)


name: USP10 deubiquitinates SNX3, CFTR (Saccharomyces cerevisiae)


name: H2O + L-seryl-tRNA(Lys) <=> L-serine + tRNA(Lys)


name: H2O + N-acetyl-L-lysine <=> acetate + L-lysine


name: RSV F binds TLR4:LY96:CD14 (Homo sapiens)


name: NAD(+) => ADP-1-deoxy-1,O(4)-didehydro-D-ribose + nicotinamide


name: (E)-caffeyl aldehyde + CoA + NADP(+) <=> (E)-caffeoyl-CoA + H(+) + NADPH


name: H2O + N(2)-acetyl-L-ornithine = acetate + L-ornithine


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Rattus norvegicus)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-di-(9Z,12Z-octadecadienoyl)-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP


name: Activated PTK6 binds CDKN1B (Homo sapiens)


name: H2O + NADP(+) + yersinopine = (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + NADPH + pyruvate


name: H2O + L-histidine + O2 => 3-(imidazol-5-yl)pyruvate + H2O2 + NH4(+)


name: CREB3L3 translocates from the cytosol to the nucleus (Canis familiaris)


name: Phosphorylation of USP8 by P-AKT (Drosophila melanogaster)


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Mus musculus)


name: tBID binds to inactive BAX protein (Bos taurus)


name: (E)-4-coumaraldehyde + H(+) + NADPH => (E)-4-coumaroyl alcohol + NADP(+)


name: Connexin synthesis (generic) (Mus musculus)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: 3-hydroxyisopentadecanoyl-CoA => (2E)-13-methyltetradecenoyl-CoA + H2O


name: diphosphate + prenol => dimethylallyl diphosphate + H2O


name: Inactivation of Rho-GTP by p190RhoGAP (Canis familiaris)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Sus scrofa)


name: GUK1 phosphorylates 6TGMP to 6TGDP (Homo sapiens)


name: Interaction of Tie2 and Dok-2 (Homo sapiens)


name: 1,4-dioxo-2-naphthoate + H(+) + phytyl diphosphate = CO2 + demethylphylloquinone + diphosphate


name: BRCA1 forms a heterodimer with BARD1 (Sus scrofa)


name: 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AH2 + O2 <=> (2R)-2-(4-aminophenyl)-L-seryl-[peptidyl-carrier protein] + A + H2O


name: SEC24A,B:SEC23A bind SEC22B (Gallus gallus)


name: 20kDa HA fragments are translocated to lysosomes (Homo sapiens)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Canis familiaris)


name: 3-methyl-2-oxobutanoate + O-acetyl-L-homoserine = (6S)-6-amino-3,3-dimethyl-2-oxoheptanedioate + acetate + H(+)


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Rattus norvegicus)


name: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH


name: [N-(6-aminohexanoyl)](n) + H2O = 6-aminohexanoate + [N-(6-aminohexanoyl)](n-1)


name: 2 sucrose = 6-kestotriose + beta-D-glucose


name: (3R)-hydroxy-(5Z)-dodecenoyl-[ACP] <=> (2E,5Z)-dodecadienoyl-[ACP] + H2O


name: WNT5A:FZD4 is endocytosed (Rattus norvegicus)


name: PEA15 binds MAPK monomers and dimers (Mus musculus)


name: Cleavage of thymine by MBD4 glycosylase (Rattus norvegicus)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Danio rerio)


name: SOS binds Grb2 bound to pFAK:NCAM1 (Rattus norvegicus)


name: 3-oxoisoheptadecanoyl-CoA + CO2 + CoA => H(+) + isopentadecanoyl-CoA + malonyl-CoA


name: Activation of TAK1 complex bound to pUb-TRAF6 (Sus scrofa)


name: L1 trans-homophilic interaction (Xenopus tropicalis)


name: MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix (Rattus norvegicus)


name: homoserine transmembrane transporter activity


name: 1-(9Z-octadecenoyl)-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate


name: (E)-4-coumarate + ATP + CoA = (E)-4-coumaroyl-CoA + AMP + diphosphate


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Mus musculus)


name: flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] + H(+) + UDP => flavanone 7-O-beta-D-glucoside + UDP-beta-L-rhamnose


name: bPIX exchanges GTP for GDP on RAC, activating it (Canis familiaris)


name: Active LTK recruits GRB2:SOS1 (Mus musculus)


name: a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Syk/Lck phosphorylate LAT (Mus musculus)


name: Activation of cytosolic AMPK by phosphorylation (Homo sapiens)


name: AH2 + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + A + dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + H(+) + L-methionine + NH4(+)


name: XDH oxidises 6MP to 6TU (Canis familiaris)


name: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate


name: PNP trimer transforms RBV to T-CONH2 (Canis familiaris)


name: CYP7B1 7-hydroxylates 25OH-CHOL (Homo sapiens)


name: TP53BP1 recruits DCLRE1C to ATM (Rattus norvegicus)


name: Rev multimer-bound HIV mRNA associates with Crm1 (Homo sapiens)


name: IMPDH tetramers binds IMPDH inhibitors (Bos taurus)


name: cholestanol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-26-hydroxycholestanol + H2O + 2 oxidized [adrenodoxin]


name: hexanal + NADP(+) <=> (E)-hex-2-enal + H(+) + NADPH


name: 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate => S-methyl-5-thio-D-ribulose 1-phosphate


name: BACH1 translocates from the cytosol to the nucleoplasm (Homo sapiens)


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Bos taurus)


name: H2O + prostaglandin D2-1-glycerol ester <=> glycerol + H(+) + prostaglandin D2


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Plasmodium falciparum)


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Homo sapiens)


name: 1'-hydroxyversicolorone + H(+) + NADPH => (2S)-versicolorone + NADP(+)


name: GRB2-1:SOS1 binds p-Y427-SHC1 (Gallus gallus)


name: (S)-malate + menaquinone-8 => menaquinol-8 + oxaloacetate


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Dictyostelium discoideum)


name: p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Sus scrofa)


name: 2-dehydro-3-deoxy-D-gluconate + H2O => D-mannonate


name: H(+) + o-quinone methide + peniphenone D <=> penilactone A


name: Keratin filaments bind cell-cell adhesion complexes (Mus musculus)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Drosophila melanogaster)


name: Phosphorylation of STAT2 (Canis familiaris)


name: 9-(9Z-octadecenoyloxy)-octadecanoate + H2O <=> (9Z)-octadecenoate + 9-hydroxy-octadecanoate + H(+)


name: arogenate dehydrogenase (NADP+) activity


name: 4-O-[(2-beta-D-glucosyl-D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP => 4-O-[(D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-alpha-D-glucose


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Homo sapiens)


name: Recruitment and activation of Cdk5 (Homo sapiens)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Rattus norvegicus)


name: N-cyclohexylformamide = cyclohexyl isocyanide + H2O


name: KDM8:Fe2+ hydroxylates an arginine residue of RPS6 (Rattus norvegicus)


name: D-serine(out) + L-alanine(in) + Na(+)(in) => D-serine(in) + L-alanine(out) + Na(+)(out)


name: 1-octanoyl-sn-glycero-3-phosphocholine => 1-octanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: organophosphate ester transmembrane transporter activity


name: AXIN is ubiquitinated by SMURF2 (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA


name: Nephrin trans-homophilic interaction (Danio rerio)


name: androst-4-ene-3,17-dione + H(+) + NADPH => NADP(+) + testosterone


name: p-PKR dimer phosphorylates PTPN2 (Gallus gallus)


name: H(+) + NADPH + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose = NADP(+) + UDP-2-acetamido-2,6-dideoxy-beta-L-talose


name: 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Bos taurus)


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Homo sapiens)


name: Active ALK dimer binds IRS1 (Rattus norvegicus)


name: oxalate + oxidized 2[4Fe-4S]-[ferredoxin] => 2 CO2 + reduced 2[4Fe-4S]-[ferredoxin]


name: ATP + creatine = ADP + H(+) + N-phosphocreatine


name: PGRMC2:Hemes translocate to the nucleus (Homo sapiens)


name: DARPP-32 is dephosphorylated on Thr75 by PP2A (Sus scrofa)


name: mitochondrial transcription factor activity


name: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate => 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA


name: p-S-TBK1 phosphorylates OPTN (Mus musculus)


name: glycyl-L-asparagine + H2O => glycine + L-asparagine


name: (S)-eriodictyol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase]


name: AKR1C1 hydrogenates PREDN,PREDL (Drosophila melanogaster)


name: STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction (Homo sapiens)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Rattus norvegicus)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Rattus norvegicus)


name: cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine => 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + teasterone => 6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Canis familiaris)


name: CHOL translocates from lysosome membrane to ER membrane (Gallus gallus)


name: MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Sus scrofa)


name: a 2-demethylmenaquinone + S-adenosyl-L-methionine <=> a menaquinone + H(+) + S-adenosyl-L-homocysteine


name: 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+) => ATP + L-aspartate + L-citrulline


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 = 5-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate


name: GDP-mannose transmembrane transporter activity


name: 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + H(+) + phosphate => ATP + geranoyl-CoA + hydrogencarbonate


name: 2 Fe(III)-[cytochrome c] + 2 thiosulfate = 2 Fe(II)-[cytochrome c] + 2 H(+) + tetrathionate


name: benzoate + S-adenosyl-L-methionine = methyl benzoate + S-adenosyl-L-homocysteine


name: mature RAS proteins translocate to plasma membrane (Drosophila melanogaster)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + UDP => a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)


name: 4-hydroxybenzoate + all-trans-hexaprenyl diphosphate <=> 4-hydroxy-3-all-trans-hexaprenylbenzoate + diphosphate


name: a dicarboxylate(in) + prostaglandin E2(out) = a dicarboxylate(out) + prostaglandin E2(in)


name: BIL dissociates from GSTA1, FABP1 (Plasmodium falciparum)


name: ATP + hydrogencarbonate + L-threonine <=> diphosphate + H2O + L-threonylcarbamoyladenylate


name: 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine = 4',7-dihydroxy-3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: L-2,4-diaminobutanoate + pyruvate <=> L-alanine + L-aspartate 4-semialdehyde


name: Phosphorylation of IRS (Xenopus tropicalis)


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Homo sapiens)


name: dermatan 4'-sulfate => chondroitin 4'-sulfate


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Gallus gallus)


name: JAK2 is phosphorylated, activated (Homo sapiens)


name: Phosphorylation (Ser5) of RNA pol II CTD (Mus musculus)


name: Recruitment of XPA and release of CAK  (Homo sapiens)


name: 1D-myo-inositol 3-phosphate + CTP + H(+) => CDP-1L-myo-inositol + diphosphate


name: Methylation of GMP-cap by RNA Methyltransferase (Schizosaccharomyces pombe)


name: benzyl isothiocyanate => benzyl thiocyanate


name: H(+) + tigogenin 3-O-beta-D-glucopyranoside + UDP => tigogenin + UDP-alpha-D-glucose


name: BRAF autophosphorylates downstream of RAP1 and NGF (Drosophila melanogaster)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 <=> 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM3 (d18:1(4E)) + CMP + H(+)


name: a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H(+) => a 3-alkylbut-(2E)-enoyl-[ACP] + CO2


name: Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Rattus norvegicus)


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Dictyostelium discoideum)


name: Insertion of correct bases opposite the lesion by POLH (Bos taurus)


name: 4 O2 + ophiobolin F + 4 reduced [NADPH--hemoprotein reductase] = 4 H(+) + 6 H2O + ophiobolin C + 4 oxidized [NADPH--hemoprotein reductase]


name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Rattus norvegicus)


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Rattus norvegicus)


name: 3,4-dimethoxy-L-phenylalanine <=> 3,4-dimethoxy-(E)-cinnamate + NH4(+)


name: NADH + 2 oxidized [2Fe-2S]-[putidaredoxin] => H(+) + NAD(+) + 2 reduced [2Fe-2S]-[putidaredoxin]


name: PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Mus musculus)


name: carbonyl sulfide + H2O = CO2 + H(+) + hydrogen sulfide


name: C3G stimulates nucleotide exchange on Rap1 (Rattus norvegicus)


name: glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Canis familiaris)


name: MITF-M-dependent IRF4 gene expression (Homo sapiens)


name: PPP1CC dephosphorylates PLK1 (Plasmodium falciparum)


name: 3 S-adenosyl-L-methionine + tricetin => 3',4',5'-O-trimethyltricetin + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: deoxycholate + NAD(+) = 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: NaS2 co-transports sulphate and two sodium ions (Rattus norvegicus)


name: 2-amino-2-deoxy-D-gluconate => 2-dehydro-3-deoxy-D-gluconate + NH4(+)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Rattus norvegicus)


name: The Ligand:GPCR:G12/13 complex dissociates (Gallus gallus)


name: NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Homo sapiens)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate = adenosine 5'-tetraphosphate + AMP + 2 H(+)


name: Basigin homodimerises (Caenorhabditis elegans)


name: (S)-indan-1-ol + NAD(+) = H(+) + indan-1-one + NADH


name: (2E)-butenoyl-CoA + CO2 + NADPH => (2S)-ethylmalonyl-CoA + NADP(+)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Rattus norvegicus)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Homo sapiens)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Mus musculus)


name: POLK incorporates dNMP opposite to damaged DNA base (Caenorhabditis elegans)


name: guanine + queuosine(34) in tRNA(Asp) => guanosine(34) in tRNA(Asp) + queuine


name: NADP(+) + neomorphine <=> H(+) + NADPH + neomorphinone


name: CAD hexamer transforms CAP to N-carb-L-Asp (Saccharomyces cerevisiae)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Homo sapiens)


name: 2-hydroxybutanoate + NADP(+) = 2-oxobutanoate + H(+) + NADPH


name: cis-trans-nepetalactol + NAD(+) <=> cis-trans-nepetalactone + H(+) + NADH


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Xenopus tropicalis)


name: 2'-deamino-2'-hydroxyparomamine + H(+) + UDP => 2-deoxystreptamine + UDP-alpha-D-glucose


name: PRKN binds p-S-Ub:MOM proteins (Bos taurus)


name: DEGS1 dehydrogenates dihydroceramide (Bos taurus)


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Drosophila melanogaster)


name: T2Rs bind bitter-tasting compounds (Sus scrofa)


name: LTA4 is converted to EXA4 by ALOX15 (Canis familiaris)


name: 3'-deoxyinosine + NH4(+) => cordycepin + H(+) + H2O


name: RAC2 binds effectors at the mitochondrial outer membrane (Xenopus tropicalis)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+) => beta-D-fructose 6-phosphate + GDP-alpha-D-mannose


name: glutathione + RX = a halide anion + an S-substituted glutathione + H(+)


name: The receptor:G-protein complex releases GDP (Mus musculus)


name: 2 H(+) + isoproturon + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 1-methyl-3-[4-(propan-2-yl)phenyl]urea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 7 CO2 + 7 CoA + 2 H2O + 5 NADP(+) + narbonolide => 6 (S)-methylmalonyl-CoA + 12 H(+) + malonyl-CoA + 5 NADPH


name: an L-amino acid tripeptide(in) + 2 H(+)(in) => an L-amino acid tripeptide(out) + 2 H(+)(out)


name: guanosine(1575) in yeast 18S rRNA + S-adenosyl-L-methionine => N(7)-methylguanosine(1575) in yeast 18S rRNA + S-adenosyl-L-homocysteine


name: Formation of Cyclin E:Cdk2 complexes (Canis familiaris)


name: 6-O-alpha-D-glucopyranosyl-D-fructose + H2O = alpha-D-glucose + D-fructose


name: Translesion synthesis across unhooked ICL by POLN (Mus musculus)


name: (2R,3S)-iso(homo)3citrate => cis-(homo)3aconitate + H2O


name: BCL2 binds BCL2 antagonists (Xenopus tropicalis)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Homo sapiens)


name: L-serine + NADP(+) => 2-aminomalonate semialdehyde + H(+) + NADPH


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Danio rerio)


name: GLB1 hydrolyses a glycosaminoglycan (Caenorhabditis elegans)


name: Caspase mediated cleavage of beta-catenin (Xenopus tropicalis)


name: corticotropin-releasing hormone receptor 1 binding


name: Activated ATM phosphorylates DCLRE1C (Mus musculus)


name: (9Z)-octadecenoate + 2-acetyl-sn-glycero-3-phosphocholine + H(+) => 1-O-(9Z)-octadecenoyl-2-O-acetyl-sn-glycero-3-phosphocholine + H2O


name: Co(I)-[methylated-thiol-specific corrinoid protein] + methanethiol = hydrogen sulfide + methyl-Co(III)-[methylated-thiol-specific corrinoid protein]


name: cAMP dissociates PKA, promoting GLI processing (Rattus norvegicus)


name: LRRC16A binds F-actin capping protein (Sus scrofa)


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Mus musculus)


name: TMEM55B translocates to the nucleus (Mus musculus)


name: ATP + O-(5'-adenylyl)-L-tyrosyl-[protein] <=> diphosphate + O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein]


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Xenopus tropicalis)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Bos taurus)


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Xenopus tropicalis)


name: NADP(+) + tetrahydrocurcumin <=> dihydrocurcumin + H(+) + NADPH


name: AMP + diphosphate + N(4)-acetylcytidine(34) in elongator tRNA(Met) => acetate + ATP + cytidine(34) in elongator tRNA(Met)


name: An anchoring protein, ZFYVE9 (SARA), recruits SMAD2/3 (Danio rerio)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Sus scrofa)


name: CUBN dissociates from 25(OH)D (Bos taurus)


name: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)


name: YKI is phosphorylated by and then dissociates from phosphorylated WTS (Drosophila melanogaster)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) => 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: beta-muricholate + lithocholoyl-CoA <=> beta-muricholoyl-CoA + lithocholate


name: glycine betaine(in) + H(+)(in) <=> glycine betaine(out) + H(+)(out)


name: bis-gamma-glutamylcystine + H(+) + NADPH => 2 gamma-L-glutamyl-L-cysteine + NADP(+)


name: NEIL1 cleaves DHU from damaged DNA (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate = diphosphate + gamma-gurjunene


name: 5-methyldeoxycytidine 5'-phosphate + 7,8-dihydrofolate => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP


name: ATP + CoA + hexadecanedioate <=> AMP + diphosphate + hexadecanedioyl-CoA


name: MT3 exchanges zinc for copper (Mus musculus)


name: diphosphate + holo-[citrate lyase ACP] => 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-[citrate lyase ACP]


name: dTDP-alpha-D-fucose + NAD(+) <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADH


name: PKA phosphorylates DARPP-32 on Thr34 (Gallus gallus)


name: POLZ elongates POLI-incorporated dNMP (Schizosaccharomyces pombe)


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Bos taurus)


name: L-aspartate 4-semialdehyde + NADP(+) + phosphate => 4-phospho-L-aspartate + H(+) + NADPH


name: gibberellin A12,oxoglutarate:oxygen oxidoreductase activity


name: CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Rattus norvegicus)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Xenopus tropicalis)


name: Spermidine  => N-acetylated spermidine (Homo sapiens)


name: 5-aminomethyl-2-thiouridine(34) in tRNA + S-adenosyl-L-methionine => 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 3-methylbutanol + NADP(+) => 3-methylbutanal + H(+) + NADPH


name: 4-methylpentanoyl-CoA + AMP + diphosphate => 4-methylpentanoate + ATP + CoA


name: Formation of alternative pathway C5 convertase (Homo sapiens)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA => 3-oxochol-4,6-dien-24-oyl-CoA + H2O


name: H(+) + S-methyl-5'-thioadenosine + spermine => S-adenosyl 3-(methylsulfanyl)propylamine + spermidine


name: CMP-5'-(3-aminopropyl)phosphonate + NADPH + O2 <=> CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate + H2O + NADP(+)


name: Polyubiquitinated NRIF migrates to the nucleus (Bos taurus)


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Saccharomyces cerevisiae)


name: Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes (Canis familiaris)


name: PANK4 hydrolyzes PPANT to pantetheine (Saccharomyces cerevisiae)


name: histone H3K4me/H3K4me2/H3K4me3 demethylase activity


name: BAP1 binds BAP1-interacting complex (Sus scrofa)


name: prunetin + UDP-alpha-D-glucuronate = prunetin-5-O-beta-D-glucuronide + UDP


name: dodecanoyl-CoA + 2 H(+) + 2 malonyl-CoA => 4-hydroxy-6-undecylpyran-2-one + 2 CO2 + 3 CoA


name: Furin cleaves pro-factor X to factor X (Gallus gallus)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Sus scrofa)


name: ent-cassa-12,15-diene + O2 + reduced [NADPH--hemoprotein reductase] => ent-11beta-hydroxycassa-12,15-diene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Proteasome degrades polyubiquitinated PTEN (Dictyostelium discoideum)


name: (S)-pinocembrin + O2 + reduced [NADPH--hemoprotein reductase] => (2S)-2-hydroxypinocembrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus (Dictyostelium discoideum)


name: (indol-3-yl)butanoate + ATP + L-cysteine = (indol-3-yl)butanoyl-L-cysteine + AMP + diphosphate + H(+)


name: Recruitment and activation of N-WASP by Cdc42 (Danio rerio)


name: RHOH binds GTP (Drosophila melanogaster)


name: PAN2-PAN3 complex partially deadenylates mRNA (Mus musculus)


name: SORD oxidizes D-sorbitol to Fru (Schizosaccharomyces pombe)


name: ATP + H2O + phenol <=> AMP + 2 H(+) + phenyl phosphate + phosphate


name: IL6R binds IL6R inhibitors (Gallus gallus)


name: HCAR2 binds HCAR2 ligands (Rattus norvegicus)


name: Autophosphorylation of PKC-theta (Caenorhabditis elegans)


name: ethanol + H(+) + hexadecanoate => ethyl hexadecanoate + H2O


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3  phosphorylates STAT1,STAT3 (Danio rerio)


name: RHOQ binds effectors at the plasma membrane (Dictyostelium discoideum)


name: glutarate(out) + 3 Na(+)(out) <=> glutarate(in) + 3 Na(+)(in)


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)


name: [DsrC protein]-S-sulfo-L-cysteine/L-cysteine = [DsrC protein]-disulfide + H(+) + sulfite


name: PP2A methylation by LCMT1 (Mus musculus)


name: Degradation of Ub-SMAD7 (Caenorhabditis elegans)


name: (E,E)-feruperate + O2 + reduced [NADPH--hemoprotein reductase] = (E,E)-piperate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Sus scrofa)


name: FAD + H(+) + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + FADH2


name: 2 L-cysteine <=> H(+) + hydrogen sulfide + L-lanthionine


name: acetyl-CoA + L-lysyl-[beta-tubulin] <=> CoA + H(+) + N(6)-acetyl-L-lysyl-[beta-tubulin]


name: G alpha (12) binds BTK (Canis familiaris)


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Schizosaccharomyces pombe)


name: 1-O-hexadecyl-sn-glycerol + ATP <=> 1-O-hexadecyl-sn-glycero-3-phosphate + ADP + H(+)


name: "Enzymes altering polypeptide conformation or assembly"


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Mus musculus)


name: CO2 + NADPH + pyruvate => (S)-malate + NADP(+)


name: 3-sulfino-L-alanine + H(+) => CO2 + hypotaurine


name: alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP-beta-L-fucose = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP + H(+)


name: aldehydo-D-ribose 5-phosphate <=> D-ribose 5-phosphate


name: demethylsuberosin + O2 + reduced [NADPH--hemoprotein reductase] <=> (7S)-marmesin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dephosphorylation of CK2-modified condensin I (Dictyostelium discoideum)


name: GLI translocates to the nucleus (Mus musculus)


name: ADP(in) + CoA(out) => ADP(out) + CoA(in)


name: HCFC1, HCFC2 bind the MLL1:MEN1 complex (Sus scrofa)


name: LONP1 degrades mitochondrial matrix proteins (Drosophila melanogaster)


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Bos taurus)


name: H(+) + N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: 2-hydroxy-4-methylpentanoate + O2 => 4-methyl-2-oxopentanoate + H2O2


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Mus musculus)


name: Formation of the 43S pre-initiation complex (Mus musculus)


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Rattus norvegicus)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Mus musculus)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Mus musculus)


name: [mycoredoxin]-L-dithiol + a hydroperoxide = [mycoredoxin]-L-disulfide + an alcohol + H2O


name: Protesomal degradation of K48polyUb-TRAF3 (Bos taurus)


name: (2E)-geranyl diphosphate + H2O <=> (2E)-geraniol + diphosphate


name: L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose => 3-O-(beta-D-xylosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: p-S363,S380,T573 RS6K translocates to the nucleus (Dictyostelium discoideum)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Rattus norvegicus)


name: 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH => 6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+)


name: DHODH:FMN binds DHODH inhibitors (Homo sapiens)


name: p-Y705,S727-STAT3 dimerizes (Mus musculus)


name: GEFs activate RhoA,B,C (Schizosaccharomyces pombe)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => (17R,18S)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CYP2A13 oxidises AFM1 to AFM1E (Sus scrofa)


name: RTC binds SARS-CoV-2 genomic RNA complement (minus strand) (Homo sapiens)


name: ATP + H2O + L-tryptophan <=> AMP + D-tryptophan + diphosphate + H(+)


name: 2 H(+) + N(4)-bis(aminopropyl)spermidine + 2 S-methyl-5'-thioadenosine => 2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine


name: diphosphate + N(6)-(dimethylallyl)adenosine 5'-phosphate => AMP + dimethylallyl diphosphate


name: Vesicular inhibitory amino acid transport (Caenorhabditis elegans)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Danio rerio)


name: 4-hydroxychlorothalonil + chloride + 2 H(+) => chlorothalonil + H2O


name: HSD11B2 dehydrogenates PREDL to PREDN (Rattus norvegicus)


name: SMURF1/2 ubiquitinates PRICKLE1 (Danio rerio)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: (Z)-(indol-3-yl)-N-(sulfonatooxy)methanimidothioate <=> (indol-3-yl)acetonitrile + sulfate + sulfur


name: MARK3 phosphorylates KSR1 (Dictyostelium discoideum)


name: TREM,CD300 binds lipids (Xenopus tropicalis)


name: Na+/H+ exchanger transport (at cell membrane) (Canis familiaris)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Rattus norvegicus)


name: FMN-N(5)-peroxide + thymine => (Z)-2-methylureidoacrylate + FMN-N(5)-oxide + 2 H(+)


name: oxalate(in) + sulfate(out) = oxalate(out) + sulfate(in)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Danio rerio)


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Xenopus tropicalis)


name: USP47 deubiquitinates POLB (Xenopus tropicalis)


name: H2O2 + tetradecanoate <=> (2R)-hydroxytetradecanoate + H2O


name: Association of procollagen type XVIII (Homo sapiens)


name: CoA + H(+) + mycothiol => 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA


name: Ub,pS335,S338,T NFE2L2 is degraded (Drosophila melanogaster)


name: 3'-phosphoadenylyl sulfate + omega-hydroxy-beta-dihydromenaquinone-9 = adenosine 3',5'-bisphosphate + H(+) + omega-sulfo-beta-dihydromenaquinone-9


name: IL37(?-218) binds p-S423,S425-SMAD3 (Canis familiaris)


name: DCN binds collagen I, II, III, VI fibrils (Rattus norvegicus)


name: ORC1 translocates to the nucleus (Sus scrofa)


name: REG3A oligomerize to form a pore complex (Sus scrofa)


name: Orexin 2 receptor can bind orexin-B neuropeptide (Gallus gallus)


name: 26S proteasome degrades Ub-NFE2L2 (Danio rerio)


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Drosophila melanogaster)


name: acetyl-CoA + L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-L-lysyl-[histone]


name: H2O + 2 NAD(+) + UDP-alpha-D-glucose <=> 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate


name: butanoyl-CoA + FAD + H(+) <=> (2E)-butenoyl-CoA + FADH2


name: dUTP(out) + UTP(in) = dUTP(in) + UTP(out)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside + phosphate => beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + H2O


name: Proteinase-activated receptors can bind thrombin (Homo sapiens)


name: 4 hydroquinone + O2 => 4 benzosemiquinone + 2 H2O


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Homo sapiens)


name: Collagen type III degradation by MMP15 (Gallus gallus)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Bos taurus)


name: Phosphorylation of the Emi1 DSGxxS degron by Plk1 (Drosophila melanogaster)


name: (R)-carnitine(out) + chloride(out) + 2 Na(+)(out) => (R)-carnitine(in) + chloride(in) + 2 Na(+)(in)


name: Arachidonic acid is oxidised to 5S-HpETE by ALOX5 (Sus scrofa)


name: A + cholest-4-en-3-one + H2O = 25-hydroxycholest-4-en-3-one + AH2


name: H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + teasterone => 6alpha-hydroxytyphasterol + O2 + reduced [NADPH--hemoprotein reductase]


name: Ubiquitinated Orc1 enters the cytosol (Mus musculus)


name: apigenin 7-O-beta-D-glucoside + H2O => apigenin + beta-D-glucose


name: RAC3 binds ER effectors (Canis familiaris)


name: octadecanoyl-CoA + taurine <=> CoA + H(+) + N-octadecanoyl-taurine


name: NTPDase5 hydrolyzes nucleoside diphosphates (Schizosaccharomyces pombe)


name: a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+) => a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: 3 H(+) + precorrin-8X = hydrogenobyrinate


name: Neurolysin degrades neurotensin (Gallus gallus)


name: AP4 transports APP from trans-Golgi network to endosome lumen (Canis familiaris)


name: Insertion of correct bases opposite the lesion by POLH (Danio rerio)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Rattus norvegicus)


name: NR3C2 binds NR3C2 antagonists (Plasmodium falciparum)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Danio rerio)


name: ATP + 2 N-(3-carboxypropanoyl)-N-hydroxycadaverine <=> AMP + bisucaberin B + diphosphate + H(+)


name: CPT1A,B transfers PALM to CAR (Rattus norvegicus)


name: hydroquinone + O2 => (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate + H(+)


name: 5beta-dihydroaldosterone + NADP(+) => aldosterone + H(+) + NADPH


name: 2-phenylacetate + ATP + CoA <=> AMP + diphosphate + phenylacetyl-CoA


name: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate <=> 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H2O


name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate (Homo sapiens)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Xenopus tropicalis)


name: Sequestration of tBID by BCL-2 (Bos taurus)


name: histidine => urocanate + NH4+ (Rattus norvegicus)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Plasmodium falciparum)


name: COASY transfers an adenylyl group from ATP to PPANT (Saccharomyces cerevisiae)


name: alpha-himachalene + diphosphate => (2E,6E)-farnesyl diphosphate


name: GBA3 hydrolyzes GlcCer (cytosol) (Bos taurus)


name: PP2A methylation by LCMT1 (Canis familiaris)


name: 5-O-[(E)-caffeoyl]-shikimate + H2O = (E)-caffeate + H(+) + shikimate


name: Endosomal TLRs pass through the Golgi (Homo sapiens)


name: D-glutamate + D-glutamine <=> gamma-D-glutamyl-D-glutamate + NH4(+)


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Rattus norvegicus)


name: 5-N(alpha)-glycyl-dTMP in DNA + AH2 + S-adenosyl-L-methionine = 5'-deoxyadenosine + 5-C(alpha)-glycyl-dTMP in DNA + A + H(+) + L-methionine


name: PDGF-BB clevage by Furin (Xenopus tropicalis)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Plasmodium falciparum)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Caenorhabditis elegans)


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Mus musculus)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Xenopus tropicalis)


name: RAC1 GDIs block activation of RAC1 (Gallus gallus)


name: 4-hydroxy-N,N,N-trimethyltryptamine + ATP => ADP + aeruginascin + H(+)


name: Aquaporins passively transport water out of cells (Bos taurus)


name: Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Danio rerio)


name: (2E)-geraniol + NAD(+) = (2E)-geranial + H(+) + NADH


name: 3-methylxanthine + H(+) + NADH + O2 = formaldehyde + H2O + NAD(+) + xanthine


name: all-trans-4-hydroxyretinol + NAD(+) <=> all-trans-4-hydroxyretinal + H(+) + NADH


name: a plastoquinone + (n+1) H(+)(in) + NADH => a plastoquinol + n H(+)(out) + NAD(+)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Schizosaccharomyces pombe)


name: KIAA1456 (TRM9L) methylates 5-carboxymethyluridine in tRNA yielding 5-methoxycarbonylmethyluridine (Homo sapiens)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + soyasapogenol B => O2 + reduced [NADPH--hemoprotein reductase] + sophoradiol


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Homo sapiens)


name: (12R)-hydroxy-(9Z)-octadecenoate + A + H2O => (9Z)-octadecenoate + AH2 + O2


name: a 3'-end 3'-phospho-ribonucleotide-RNA + GTP => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + diphosphate + GMP


name: (R)-carnitinamide + H2O <=> (R)-carnitine + NH4(+)


name: MMAA:MUT binds AdoCbl (Rattus norvegicus)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Homo sapiens)


name: 2 2-oxoglutarate + gibberellin A53 + H(+) + 3 O2 <=> 3 CO2 + gibberellin A20 + 2 H2O + 2 succinate


name: Fe-coproporphyrin III + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + 2 CO2 + heme b + 2 L-methionine


name: cyclo-acetoacetyl-L-tryptophan + dimethylallyl diphosphate => beta-cyclopiazonate + diphosphate


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O <=> L-threonyl-[protein] + N-acetyl-D-galactosamine


name: Endonucleolytic RISC hydrolyzes target RNAs (Drosophila melanogaster)


name: GTP-binding activates eEF2 (Dictyostelium discoideum)


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Drosophila melanogaster)


name: acetoacetate + succinyl-CoA => 3-oxoadipate + acetyl-CoA


name: CysGly translocates from extracellular region to cytosol (Homo sapiens)


name: dAMP + H2O = 2-deoxy-D-ribose 5-phosphate + adenine


name: a 5'-end triphospho-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Plasmodium falciparum)


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)


name: CoA-disulfide reductase (NADPH) activity


name: pseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-homocysteine


name: KCTD1 binds TFAP2 homo- and heterodimers (Drosophila melanogaster)


name: 9-decenoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(non-8-en-1-yl)-pyran-2-one + 2 CO2 + 3 CoA


name: Loading of dopamine into synaptic veiscles (Homo sapiens)


name: 1-acyl LPG is acylated to PG by LPGAT (Drosophila melanogaster)


name: ADP + estrone 3-sulfate(out) + H(+) + phosphate => ATP + estrone 3-sulfate(in) + H2O


name: 2 H(+) + L-aspartate + 3 NADPH + 3 O2 = 2-nitrobutanedioate + 4 H2O + 3 NADP(+)


name: Regulation of KIF23 (MKLP1) by phosphorylation (Bos taurus)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NADP(+) <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 H(+) + 8 NADPH


name: FAD + H(+) + pentadecanoyl-CoA <=> (2E)-pentadecenoyl-CoA + FADH2


name: SCARB1:ligand is endocytosed (Rattus norvegicus)


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Drosophila melanogaster)


name: 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O => [hyaluronan](n)


name: RAB5 and GAPVD1 bind AP-2 (Caenorhabditis elegans)


name: structural constituent of collagen and cuticulin-based cuticle


name: D-galactose(out) + 2 Na(+)(out) = D-galactose(in) + 2 Na(+)(in)


name: Activation of proMMP8 (Canis familiaris)


name: H2O + N(2)-(3-hydroxy-3-methylhexanoyl)-L-glutaminate => 3-hydroxy-3-methylhexanoate + L-glutamine


name: ATP + Fe(III)-enterobactin(out) + H2O => ADP + Fe(III)-enterobactin(in) + H(+) + phosphate


name: RHOA:GTP binds ROCK, activating it (Danio rerio)


name: H(+) + NADH + O2 + quinolin-2-ol = 5,6-dihydroquinoline-2,5,6-triol + NAD(+)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Saccharomyces cerevisiae)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate


name: adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate => adenosylcob(III)alamin 5'-phosphate + GMP + H(+)


name: ORC6 binds KPNA1 or KPNA6 (Xenopus tropicalis)


name: a 2,3-di-O-phytanyl-sn-glycerophospholipid + AH2 + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + A + a macrocyclic archaeaol phospholipid + 2 H(+) + 2 L-methionine


name: S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity


name: Translocation of YAP1 to the nucleus (Bos taurus)


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Bos taurus)


name: acetyl-CoA + H2O + pyruvate <=> (3R)-citramalate + CoA + H(+)


name: Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 (Homo sapiens)


name: UNC93B1 delivers endosomal full-length TLRs to endolysosome (Homo sapiens)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Schizosaccharomyces pombe)


name: XPO1-dependent export of p-S69,S73 MITF-M (Homo sapiens)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Bos taurus)


name: p38MAPK phosphorylates MSK1 (Rattus norvegicus)


name: CoA + NADP(+) + pyruvate <=> acetyl-CoA + CO2 + NADPH


name: (1S,2S,4S)-dihydrocarveol + NAD(+) => (1S,4S)-dihydrocarvone + H(+) + NADH


name: Phosphorylated STAT92E dimer is dephosphorylated by PTP61F isoform 2 (Drosophila melanogaster)


name: 2 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) => 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)


name: N-decanoyl-(2S)-hydroxyglycine = decanamide + glyoxylate


name: ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Mus musculus)


name: 9alpha-copalyl diphosphate <=> diphosphate + stemod-13(17)-ene


name: TLR folding by chaperones GP96 and CNPY3 (Mus musculus)


name: aldehydo-D-galacturonate(out) + H(+)(out) = aldehydo-D-galacturonate(in) + H(+)(in)


name: Formation of NR-MED1 Coactivator Complex (Drosophila melanogaster)


name: a ganglioside Ac-O-8-GD2(d18:1(4E)) => a ganglioside Ac-O-9-GD2(d18:1(4E))


name: MeR-PIWIL4:2'-O-methyl-piRNA:TDRD9:MAEL:TDRKH dissociates and MeR-PIWIL4:2'-O-methylpiRNA, TDRD9, MAEL translocate from cytosol to nucleus in an unknown association and order of events (Homo sapiens)


name: pro-defensin alpha 5 is secreted (Homo sapiens)


name: EGR2 and SOX10 bind the MAG gene (Homo sapiens)


name: Phosphorylation of MEF2 proteins by p38 (Schizosaccharomyces pombe)


name: 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine => a 1,2-diacyl-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: p-S303,307-HSF1 binds YWHAE (14-3-3) (Schizosaccharomyces pombe)


name: a (3Z)-enoyl-CoA => a 4-saturated (2E)-enoyl-CoA


name: Activated FGFR4 mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Danio rerio)


name: H(+) + phenylglyoxylate <=> benzaldehyde + CO2


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Caenorhabditis elegans)


name: H2O + hexadecanoyl-CoA <=> CoA + H(+) + hexadecanoate


name: SARS-CoV-2 3a induces potassium efflux (Homo sapiens)


name: Association of  PARVA with TESK1 (Sus scrofa)


name: COLEC12 (SCARA4) binds ligands (Bos taurus)


name: High kinase activity BRAF complexes phosphorylate MAP2Ks (Homo sapiens)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Bos taurus)


name: E1 mediated ubiquitin activation (Dictyostelium discoideum)


name: COX10 transforms heme to heme O (Schizosaccharomyces pombe)


name: Downregulation of c-Kit signaling by SOCS6 (Homo sapiens)


name: RAS:GTP binds RAL GDS proteins (Canis familiaris)


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Mus musculus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: TP53 binds the CDKN1A promoter (Homo sapiens)


name: 6-amino-2-oxohexanoate + H2O2 <=> 5-aminopentanoate + CO2 + H2O


name: 9-decenoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one + 3 CO2 + 4 CoA


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Drosophila melanogaster)


name: GAB1 recruits CRK,CRKL to MET (Homo sapiens)


name: diglucosyl-enterobactin + UDP-alpha-D-glucose => H(+) + triglucosyl-enterobactin + UDP


name: dihydroxyacetone phosphate => D-glyceraldehyde 3-phosphate


name: 4-nitro-6-oxohepta-2,4-dienedioate => 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite


name: H(+) + L-arginine + NADH + O2 => H2O + N(omega)-hydroxy-L-arginine + NAD(+)


name: glutathione dehydrogenase (ascorbate) activity


name: 17alpha-hydroxywithaferin A + UDP-alpha-D-glucose = 17alpha-sitoindoside IX + H(+) + UDP


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + glycerol


name: ESTG binds ESR2:chaperone complex (Rattus norvegicus)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RANBP2 SUMOylates PML with SUMO2 (Drosophila melanogaster)


name: PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)


name: a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O => a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Homo sapiens)


name: RAC2 translocates to the ER membrane (Danio rerio)


name: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alpha-aminoacyl-[protein]


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Sus scrofa)


name: 4-guanidinobutanoate + NH4(+) => 4-guanidinobutanamide + H2O


name: all-trans-heptaprenyl diphosphate <=> beta-heptaprene + diphosphate


name: Coumarin is 7-hydroxylated by CYP2A6 (Xenopus tropicalis)


name: BRF1 Complex recruits RNA degradation activities (Mus musculus)


name: Serine phosphorylation of STATs (Sus scrofa)


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Homo sapiens)


name: a 2'-deoxyribonucleoside 5'-diphosphate + H2O <=> a 2'-deoxyribonucleoside 5'-phosphate + H(+) + phosphate


name: (R)-3-hydroxy-2-methylpropanoate + NAD(+) = (R)-2-methyl-3-oxopropanoate + H(+) + NADH


name: Monoiodinated tyrosine can be deiodinated (Xenopus tropicalis)


name: (-)-secoisolariciresinol + 2 NAD(+) <=> (-)-matairesinol + 2 H(+) + 2 NADH


name: (4R)-hydroxysphinganine + 2-hydroxyhexacosanoyl-CoA <=> CoA + H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: acetyl-CoA + N-terminal L-methionyl-L-alanyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-alanyl-[protein]


name: ICOS binds ICOSL/B7-H2 (Canis familiaris)


name: 3-hydroxy-2,4-dioxopentyl phosphate + CoA => acetyl-CoA + dihydroxyacetone phosphate


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Homo sapiens)


name: THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation (Rattus norvegicus)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Saccharomyces cerevisiae)


name: 3-methyl-2-oxobutanoate + H2O2 + NH4(+) => D-valine + H2O + O2


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Homo sapiens)


name: PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Dictyostelium discoideum)


name: H2O + neurotensin = L-tyrosyl-L-isoleucyl-L-leucine + neurotensin(1-10)


name: (S)-malate(in) + glycolate(out) => (S)-malate(out) + glycolate(in)


name: Activation of RAC1 by the PXN:CRK complex (Canis familiaris)


name: dimethyl sulfide + H2O + menaquinone-8 => dimethyl sulfoxide + menaquinol-8


name: PRKAA2 phosphorylates nuclear NFE2L2 (Gallus gallus)


name: JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Homo sapiens)


name: DENND1s exchange GTP for GDP on RAB35 (Dictyostelium discoideum)


name: Resolution of sister chromatids (Rattus norvegicus)


name: (1S,4S)-5-oxo-1,2-campholide + FMN + H(+) + H2O => (1S,4S)-bornane-2,5-dione + FMNH2 + O2


name: BLK gene expression is stimulated by the complex of RUNX1 and ELF1, ELF2 or PAX5 (Homo sapiens)


name: DLST transfers succinyl to CoA (Dictyostelium discoideum)


name: H2O + NAD(+) + succinate semialdehyde + trimethylamine => 4-(trimethylamino)butanoate + H(+) + NADH + O2


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Homo sapiens)


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Plasmodium falciparum)


name: Ca permeable AMPA receptor ligand binding (Danio rerio)


name: Neurotensin receptors can bind neurotensins (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+) => a CDP-1,2-diacyl-sn-glycerol + L-serine


name: Caspase-mediated cleavage of Rock-1 (Gallus gallus)


name: PKM dephosphorylates PEP to PYR (Schizosaccharomyces pombe)


name: a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + a 5'-end dephospho-ribonucleoside-RNA <=> a ribonucleotidyl-ribonucleotide-RNA + GMP + H(+)


name: 3-ADP-2-phosphoglycerate + H2O => 3-ADP-glycerate + phosphate


name: CDC42 and PIP2 bind WASL, activating it (Mus musculus)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate <=> 5-oxo-(6E,8Z,11Z,14Z)-eicosatetraenoate + H2O


name: PAK1-3 phosphorylates VE-cadherin (Drosophila melanogaster)


name: MAPK4,6 translocate to nucleus (Gallus gallus)


name: (9Z,12Z)-octadecadienoyl-CoA + FAD + H(+) => (2E,9Z,12Z)-octadecatrienoyl-CoA + FADH2


name: Transport (influx) of bile salts and acids by OATP-A (Danio rerio)


name: (3R)-3-hydroxydodecanoyl-CoA + NAD(+) <=> 3-oxododecanoyl-CoA + H(+) + NADH


name: WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)


name: (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate => ATP + S-disulfanyl-L-cysteine + tRNA(Cys)


name: (2E)-tetracosenoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + oxidized [electron-transfer flavoprotein] + tetracosanoyl-CoA


name: LRTOMT transfers Met to DA, forming 3MT (Gallus gallus)


name: 2-oxoaldehyde + H2O + NADP(+) => a 2-oxocarboxylate + 2 H(+) + NADPH


name: Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Rattus norvegicus)


name: 1-acyl LPS is acylated to PS by LPSAT (Sus scrofa)


name: (R)-carnitine(in) + glycine betaine(out) <=> (R)-carnitine(out) + glycine betaine(in)


name: 2-methylpropanoate + CoA + H(+) => 2-methylpropanoyl-CoA + H2O


name: NADP(+) + sn-glycerol 1-phosphate => dihydroxyacetone phosphate + H(+) + NADPH


name: GRIN2A gene expression is stimulated by MECP2 (Homo sapiens)


name: H2O + N(6)-biotinyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: beta-L-galactose 1-phosphate + GDP + H(+) => GDP-beta-L-galactose + phosphate


name: Caspase-mediated cleavage of plectin-1 (Rattus norvegicus)


name: a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase] => a 21-hydroxy-C21-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + 2 NADPH + octadecanoyl-CoA = CoA + 2 NADP(+) + octadecan-1-ol


name: AH2 + archaetidylglycerol + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + macrocyclic archaetidylglycerol


name: (2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate


name: PTGS2 dimer oxidises DHA to 13-HDHA (Canis familiaris)


name: Docking of Mature Replication Dependent Histone mRNA with the NPC (Homo sapiens)


name: STING binds TRIM32 or TRIM56  (Sus scrofa)


name: PKA phosphorylates DARPP-32 on Thr34 (Homo sapiens)


name: estrone 3-sulfate(out) + propanoate(in) => estrone 3-sulfate(in) + propanoate(out)


name: D-cysteine + H2O + O2 => 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Homo sapiens)


name: cadmium ion transmembrane transporter activity


name: H2O + S-acylglutathione <=> a carboxylate + glutathione + H(+)


name: (2S)-2-aminobutanoate + 5-(3,3-dimethylguanidino)-2-oxopentanoate => 2-oxobutanoate + N(omega),N(omega)-dimethyl-L-arginine


name: SRC-1 bound to ARRB2 is not activated (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-leucine = H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-leucine


name: (3R)-hydroxyoctadecanoyl-CoA + NAD(+) = 3-oxooctadecanoyl-CoA + H(+) + NADH


name: HTR1A binds HTR1A agonists (Mus musculus)


name: urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR (Bos taurus)


name: GPER:Heterotrimeric G-protein Gs binds ESTG (Homo sapiens)


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Dictyostelium discoideum)


name: (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + H(+) + NADH => (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-2,6-dimethyloct-6-enoyl-CoA + NAD(+)


name: 2,2-dihydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2-hydroxyspirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Cleavage of uracil by TDG glycosylase (Gallus gallus)


name: NEIL2 cleaves 5-OHU from damaged DNA (Homo sapiens)


name: PLC-gamma1 hydrolyses PIP2 (Mus musculus)


name: Bombesin-like receptors bind bombesin homologues (Homo sapiens)


name: 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalenolactone => 2 H(+) + O2 + pentalenolactone F + 2 reduced [2Fe-2S]-[ferredoxin]


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Homo sapiens)


name: chloramphenicol(in) + H(+)(out) = chloramphenicol(out) + H(+)(in)


name: Formation of ADAR2  homodimer (Caenorhabditis elegans)


name: DDR2 binds collagen type I, II, III, V, X fibrils (Gallus gallus)


name: Phosphorylation of FANCG at S7 (Gallus gallus)


name: ATP + L-threonyl-[protein] <=> 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate


name: acetyl-CoA + phosphate <=> acetyl phosphate + CoA


name: 2-dehydro-3-deoxy-D-arabinonate + H2O => D-xylonate


name: 5-C(alpha)-glycyl-dTMP in DNA + H(+) = 5-aminoethyl-dUMP in DNA + CO2


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine


name: H(+) + H2O + L-citrulline + S-nitroso-L-cysteinyl-[NO transferase protein] => L-cysteinyl-[NO transferase protein] + N(omega)-hydroxy-L-arginine + O2


name: (20S)-ginsenoside Rd + 2 H2O <=> (20S)-ginsenoside C-K + 2 D-glucose


name: ERBB4s80:STAT5A complex translocates to the nucleus (Caenorhabditis elegans)


name: Activation of EPACs by cAMP (Gallus gallus)


name: Beta-defensins bind microbial membranes causing disruption (Homo sapiens)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Sus scrofa)


name: Formation of a heteromeric BMP receptor complex (Sus scrofa)


name: Association of procollagen type XXIII (Canis familiaris)


name: KCNK dimers transport K+ from cytosol to extracellular region (Bos taurus)


name: UBQLNs bind UIM-containing adaptor proteins (Schizosaccharomyces pombe)


name: O2 + torulene = 3-methyl-2-butenal + 4'-apo-beta-carotenal


name: RABGGTA binds RABGGTB (Saccharomyces cerevisiae)


name: a 7-hydroxyisoflavone 7-O-beta-D-glucoside + H(+) + UDP => a 7-hydroxyisoflavone + UDP-alpha-D-glucose


name: Association of Cyclin A with the APC/C (Xenopus tropicalis)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Plasmodium falciparum)


name: glycine betaine(out) => glycine betaine(in)


name: GLI3R translocates to the nucleus (Homo sapiens)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Rattus norvegicus)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Sus scrofa)


name: RHOD translocates to the Golgi membrane (Sus scrofa)


name: a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol <=> a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+)


name: a neolactoside nLc4Cer + GDP-beta-L-fucose => a neolactoside III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Danio rerio)


name: osmolarity-sensing monoatomic cation channel activity


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Bos taurus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> diphosphate + fusoxypene A


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Mus musculus)


name: an acyl-CoA + H(+) + malonyl-CoA = a 3-oxoacyl-CoA + CO2 + CoA


name: sodium-transporting ATP synthase activity, rotational mechanism


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Rattus norvegicus)


name: a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GM2 + H(+) + UDP


name: 3-oxosphinganine + tetradecanoyl-CoA => CoA + H(+) + N-tetradecanoyl-3-oxosphinganine


name: Release Of ADP From Myosin (Gallus gallus)


name: H(+)(in) + L-asparagine(out) + Na(+)(out) <=> H(+)(out) + L-asparagine(in) + Na(+)(in)


name: maltose + H2O => 2 D-glucose (sucrase-isomaltase) (Schizosaccharomyces pombe)


name: RGS proteins bind GNB5 and CCT/TRiC (Caenorhabditis elegans)


name: PIAS1,3 SUMOylates NR5A1 with SUMO2 (Homo sapiens)


name: FANCD2 deubiquitination by USP1:WDR48 (Homo sapiens)


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Homo sapiens)


name: 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2 => 3'-N-debenzoyltaxol + A + H2O


name: apo-Transferrin dissociates from the receptor complex (Rattus norvegicus)


name: Dephosphorylation of Lck-pY505 by CD45 (Sus scrofa)


name: (+)-medicarpin + H2O => (3S,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol


name: (+)-artemisinic aldehyde + H2O + NADP(+) = (+)-artemisinate + 2 H(+) + NADPH


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Homo sapiens)


name: Expression of GLI1 is repressed by GLI3R in the absence of Hh signaling (Homo sapiens)


name: (+)-valencene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (+)-nootkatone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 2 Na(+)(in) + tauronorcholate(in) => 2 Na(+)(out) + tauronorcholate(out)


name: 2 1-O-(trans-sinapoyl)-beta-D-glucose <=> 1,2-di-O-sinapoyl beta-D-glucose + D-glucose


name: CDP(out) + CDP-L-ribitol(in) <=> CDP(in) + CDP-L-ribitol(out)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2 = 2-dehydro-D-glucose + H2O2 + L-tyrosine


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Homo sapiens)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Homo sapiens)


name: 2-phenylacetaldehyde + H(+) + NADPH <=> 2-phenylethanol + NADP(+)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Canis familiaris)


name: 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AH2 + O2 => (2R)-2-(4-aminophenyl)-L-seryl-[peptidyl-carrier protein] + A + H2O


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-D-GlcNAc-R + CMP + H(+)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Rattus norvegicus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: FLNA binds PAK1 (Caenorhabditis elegans)


name: FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Rattus norvegicus)


name: L-lysine => H2O + L-2-aminohexano-6-lactam


name: fatty acid transmembrane transporter activity


name: SHC1-2 bound to MET recruits GRB2:SOS1 (Gallus gallus)


name: 2-oxoglutarate + O2 + thebaine => 6-O-demethylthebaine + CO2 + formaldehyde + H(+) + succinate


name: (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O


name: p-S318,221-HuR binds mRNA (Canis familiaris)


name: a 5'-end CoA-ribonucleoside in mRNA + H2O = (R)-4'-phosphopantetheine + a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + 2 H(+)


name: RNA demethylases demethylate N6-methyladenosine RNA (Danio rerio)


name: CBL autoubiquitinates (Plasmodium falciparum)


name: Monoubiquitinated PTEN translocates to the nucleus (Homo sapiens)


name: (R)-3,3-dimethylmalate + NAD(+) <=> 3-methyl-2-oxobutanoate + CO2 + NADH


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = a 1-O-alkyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: anthocyanin A3 + malonyl-CoA => anthocyanin A5 + CoA


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: CYSLT2 binds LTC4,LTD4,LTE4 (Rattus norvegicus)


name: GDIs block activation of RHOG (Dictyostelium discoideum)


name: CK2:FACT phosphorylates TP53 (Bos taurus)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Mus musculus)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Homo sapiens)


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Bos taurus)


name: Exocytosis of azurophil granule membrane proteins (Schizosaccharomyces pombe)


name: aldehydo-D-glucuronate(in) + H(+)(in) <=> aldehydo-D-glucuronate(out) + H(+)(out)


name: L-histidyl-[protein] + NAD(+) => H(+) + N(tele)-(ADP-D-ribosyl)-L-histidyl-[protein] + nicotinamide


name: DLAT trimer transfers acetyl to CoA (Bos taurus)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Danio rerio)


name: ULK1 is dephosphorylated (Caenorhabditis elegans)


name: (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphate + choline + H(+)


name: Interaction of DAP12 and IREM2 (Rattus norvegicus)


name: ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Rattus norvegicus)


name: 3-sulfanyl-1-hexanol + NH4(+) + pyruvate => H2O + S-3-(hexan-1-ol)-L-cysteine


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Canis familiaris)


name: (3R)-hydroxyoctadecanoyl-CoA => (2E)-octadecenoyl-CoA + H2O


name: mitochondrial single-subunit type RNA polymerase binding


name: CPT1A,B transfers PALM to CAR (Bos taurus)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Homo sapiens)


name: 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H2O => (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-3-hexadecanoyl-sn-glycerol + H(+)


name: H2O + norspermine + O2 <=> 3-aminopropanal + H2O2 + norspermidine


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Sus scrofa)