name: 11alpha-hydroxy-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] => 11-oxo-beta-amyrin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH => (1R,2S)-ephedrine + NAD(+)


name: MRN complex bound to DNA ends recruits ATM (Schizosaccharomyces pombe)


name: H2O + L-prolinamide => L-proline + NH4(+)


name: CDK5 phosphorylates TP53 (Drosophila melanogaster)


name: Formation of nonameric complex (Bos taurus)


name: ASIC trimers:H+ transport extracellular Na+ to cytosol (Xenopus tropicalis)


name: 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + phosphate


name: PDCL binds G-protein beta and TRiC/CCT (Homo sapiens)


name: (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one <=> (3R)-3-isopropenyl-6-oxoheptanoate + H(+)


name: Phosphorylation of Cx43 by c-src (Rattus norvegicus)


name: creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Rattus norvegicus)


name: Inactive RAFs bind YWHAB (Drosophila melanogaster)


name: Active ARF recruits coatomer (Dictyostelium discoideum)


name: (R)-2-benzylsuccinyl-CoA + succinate => (R)-2-benzylsuccinate + succinyl-CoA


name: CLPXP binds mitochondrial matrix proteins (Bos taurus)


name: Surface deployment of platelet dense granule membrane components (Drosophila melanogaster)


name: S-adenosyl-L-methionine + sarcosine <=> H(+) + N,N-dimethylglycine + S-adenosyl-L-homocysteine


name: ALPK1 phosphorylates TIFA (Mus musculus)


name: BTK in PIP3:BTK:G beta-gamma complex is activated (Gallus gallus)


name: SUMOylation of XPC (Schizosaccharomyces pombe)


name: OCT3 mediates renal uptake of organic cations (Mus musculus)


name: a D-hexose + an acyl phosphate => a carboxylate + D-hexose phosphate + H(+)


name: 4beta-hydroxymethyl-4alpha-methylzymosterol + H2O + NAD(+) => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADH + O2


name: 2-4 nt.backtracking of Pol II complex on the HIV-1 template leading to elongation pausing (Homo sapiens)


name: [(1->4)-beta-D-mannuronosyl](n) + GDP-alpha-D-mannuronate <=> [(1->4)-beta-D-mannuronosyl](n+1) + GDP + H(+)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Mus musculus)


name: an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose => an anthocyanidin 3,5-di-O-beta-D-glucoside + 2 H(+) + UDP


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Mus musculus)


name: Replication transcription complex binds SARS-CoV-2 genomic RNA (Homo sapiens)


name: RAC3 GDIs block activation of RAC3 (Drosophila melanogaster)


name: ST translocates from cytosol to extracellular region (Homo sapiens)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Sus scrofa)


name: ESR1 binds ESR1 antagonists (Rattus norvegicus)


name: Addition of galactose by beta 4-galactosyltransferases (Bos taurus)


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Sus scrofa)


name: [thioredoxin]-disulfide + H2O + L-methionine => [thioredoxin]-dithiol + L-methionine (R)-S-oxide


name: SMURF2 ubiquitinates SMAD2 (Canis familiaris)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = (+)-costunolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: FMN + H(+) + H2O + methanesulfonate => FMNH2 + methanesulfinate + O2


name: AKT phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Schizosaccharomyces pombe)


name: Conversion of malonyl-CoA and acetyl-CoA to palmitate (Drosophila melanogaster)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Homo sapiens)


name: (9Z)-hexadecenoate + 13-hydroxy-octadecanoate + H(+) => 13-(9Z-hexadecenoyloxy)-octadecanoate + H2O


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Homo sapiens)


name: a primary nitroalkane + H2O + O2 => an aldehyde + H(+) + H2O2 + nitrite


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Bos taurus)


name: Cleavage of Procaspase-7 by the apoptosome (Bos taurus)


name: TRIM33 monoubiquitinates SMAD4 (Rattus norvegicus)


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+) + H2O => Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + N-(2,3-dihydroxybenzoyl)-L-serine


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Gallus gallus)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)


name: Aquaporin-7 passively transports glycerol out of cell (Sus scrofa)


name: H2O + N(2)-(4-aminobutanoyl)-L-arginine <=> 4-aminobutanoate + L-arginine


name: (13Z)-docosenoyl-CoA + H(+) + malonyl-CoA = (15Z)-3-oxotetracosenoyl-CoA + CO2 + CoA


name: (S)-malate(in) + 3 Na(+)(in) => (S)-malate(out) + 3 Na(+)(out)


name: SUMOylation of Histone H4 with SUMO1 (Dictyostelium discoideum)


name: a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol <=> a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+)


name: IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)


name: (5'S,6'S)-C-glycyluridine + acetaldehyde => L-threonine + uridine-5'-aldehyde


name: KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 (Bos taurus)


name: Binding of Grb10 to the insulin receptor (Homo sapiens)


name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 (Bos taurus)


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Rattus norvegicus)


name: cholate + NADP(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADPH


name: luteolin + S-adenosyl-L-methionine = H(+) + luteolin 7-methyl ether + S-adenosyl-L-homocysteine


name: Aquaporin-7 passively transports glycerol out of cell (Caenorhabditis elegans)


name: (9Z)-octadecen-1-ol + (9Z)-octadecenoyl-CoA => 1-O-(9Z)-octadecenyl (9Z)-octadecenoate + CoA


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Xenopus tropicalis)


name: calcium-independent phospholipase A2 activity


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Danio rerio)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Rattus norvegicus)


name: Allergen dependent IgE bound FCERI aggregation (Homo sapiens)


name: 15-methylhexadecasphinganine + NADP(+) = 3-dehydro-15-methylhexadecasphinganine + H(+) + NADPH


name: SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Drosophila melanogaster)


name: dodecanal + H2O + O2 => dodecanoate + H(+) + H2O2


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Bos taurus)


name: a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E)) + GDP-beta-L-fucose <=> alpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + GDP + H(+)


name: a ganglioside GA1 + GDP-beta-L-fucose => a ganglioside Fuc-GA1 + GDP + H(+)


name: L-arabinitol + NAD(+) = H(+) + L-arabinose + NADH


name: asperaculane D + O2 + reduced [NADPH--hemoprotein reductase] = asperaculane E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-hydroxyisobutanoyl-CoA <=> acetone + formyl-CoA


name: Ghrelin O-acyltransferase decanoylates Proghrelin (Canis familiaris)


name: PDCD1 binds PDCD1 inhibitors (Mus musculus)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + H(+) + phosphate


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Bos taurus)


name: Cleavage of factor XII variant by activated thrombin (Homo sapiens)


name: a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine <=> a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + H(+) + S-adenosyl-L-homocysteine


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 24S,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 => albonoursin + H2O2


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Homo sapiens)


name: ADRM1:26S proteaseome binds USP14 (Drosophila melanogaster)


name: a Fe(III)-siderophore(out) + ATP + H2O = a Fe(III)-siderophore(in) + ADP + H(+) + phosphate


name: Ligand-independent dimerization of overexpressed FGFR1b (Homo sapiens)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + H(+) + hexadecanoate


name: CTP + H(+) + Mo-molybdopterin => diphosphate + Mo-molybdopterin cytosine dinucleotide


name: (6S)-6-amino-3,3-dimethyl-2-oxoheptanedioate + acetate + H(+) => 3-methyl-2-oxobutanoate + O-acetyl-L-homoserine


name: a 1-acyl-sn-glycerol + H2O = a fatty acid + glycerol + H(+)


name: ATP + UDP-N-acetyl-alpha-D-glucosamine = ADP + H(+) + UDP-N-acetyl-alpha-D-glucosamine 3'-phosphate


name: PLG(20-810) binds anti-fibrinolytics (Canis familiaris)


name: BAD displaces tBID from BCL-2 sequestration (Canis familiaris)


name: cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25S)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA (Drosophila melanogaster)


name: CHRM2 binds CHRM2 antagonists (Rattus norvegicus)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose => an isogloboside iGb3Cer (d18:1(4E)) + H(+) + UDP


name: 3-oxo-(11Z)-octadecenoyl-CoA + H(+) + NADPH <=> (R)-3-hydroxy-(11Z)-octadecenoyl-CoA + NADP(+)


name: Formation of FACT complex (Caenorhabditis elegans)


name: C3a receptor binds anaphylatoxin C3a (Bos taurus)


name: The receptor:G-protein complex releases GDP (Homo sapiens)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Drosophila melanogaster)


name: DHAP is converted to 1-acyl GO3P by GNPAT (Canis familiaris)


name: Cytosolic CMs translocate to extracellular region (Gallus gallus)


name: PSMD14 cleaves K63-linked ubiquitin (Saccharomyces cerevisiae)


name: L-seryl-[protein] + UTP => diphosphate + uridylyl-L-seryl-[protein]


name: GSTO1 dimer reduces methylarsonate to methylarsonite (Drosophila melanogaster)


name: di-trans,undeca-cis-tetradecaprenyl diphosphate + 11 diphosphate => (2Z,6E)-farnesyl diphosphate + 11 isopentenyl diphosphate


name: RANBP2 SUMOylates PML with SUMO1 (Mus musculus)


name: Aquaporins passively transport water into cells (Gallus gallus)


name: Formation of nonameric complex (Mus musculus)


name: Translocation of activated BAD protein to mitochondria (Canis familiaris)


name: RHOA:GTP binds RHPN1 or RHPN2 (Danio rerio)


name: p-PKR dimer phosphorylates SPHK1 (Drosophila melanogaster)


name: 26S proteasome degrades PolyUb-RUNX2 (Caenorhabditis elegans)


name: VCAM1 binds Integrin alpha4beta1 (Mus musculus)


name: NFE2L2 translocates from cytosol to nucleoplasm (Caenorhabditis elegans)


name: glycocholate + H2O <=> cholate + glycine


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Canis familiaris)


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Bos taurus)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Saccharomyces cerevisiae)


name: Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Homo sapiens)


name: chloride(out) + N-methyl-L-proline(out) + 2 Na(+)(out) = chloride(in) + N-methyl-L-proline(in) + 2 Na(+)(in)


name: Formation of p-STAT1 homodimer (Canis familiaris)


name: ADP + H(+) + valienone 7-phosphate => ATP + valienone


name: a 3-(omega-methylsulfanyl)alkylmalate <=> a 2-(omega-methylsulfanyl)alkylmaleate + H2O


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Drosophila melanogaster)


name: NAD(+) + UDP-alpha-D-glucuronate = CO2 + NADH + UDP-beta-L-threo-pentopyranos-4-ulose


name: "UDP-glucuronic acid oxidase (UDP-4-keto-hexauronic acid decarboxylating)"


name: p-PKR dimer phosphorylates TP53 tetramer (Danio rerio)


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Gallus gallus)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate => H2O + kynurenate


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Saccharomyces cerevisiae)


name: OCT1 transports organic cations into hepatic cells (Bos taurus)


name: miR-26A and B bind to the 3'UTR of the GREB1 mRNA (Homo sapiens)


name: Oligomerization  of BAK at the mitochondrial membrane (Gallus gallus)


name: CHM binds RGGT (Saccharomyces cerevisiae)


name: 3-oxotetradecanoyl-CoA + H(+) + NADH => (3S)-hydroxytetradecanoyl-CoA + NAD(+)


name: an L-alpha-amino acid + H2O + O2 <=> a 2-oxocarboxylate + H2O2 + NH4(+)


name: Caspase-mediated cleavage of Lamin B1 (Canis familiaris)


name: 1-O-hexadecyl-2-acetyl-3-tetradecanoyl-sn-glycerol + CoA => 1-O-hexadecyl-2-acetyl-sn-glycerol + tetradecanoyl-CoA


name: (Z)-3-ureidoacrylate + H(+) + H2O = (Z)-3-aminoacrylate + CO2 + NH4(+)


name: Cytosolic PLK1 translocates to the nucleus (Danio rerio)


name: Disassembly of tight junctions (Bos taurus)


name: AP-1 transcription factor forms a complex with STAT92E and DSP1 which displaces REL-68 from its target gene (Drosophila melanogaster)


name: GMP + methylglyoxal => N(2)-(1-hydroxy-2-oxopropyl)-GMP


name: Defective POMGNT1 does not transfer GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 (Homo sapiens)


name: a dicarboxylate + 2 H(+) + NADH => an omega-oxo fatty acid + H2O + NAD(+)


name: 4-coumaroyl-CoA + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside = a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Danio rerio)


name: 2-methylpropanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] => CoA + N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein]


name: Endocytosis of Ca impermeable AMPA receptors (Rattus norvegicus)


name: Cytosolic JET binds to CRY, facilitating its ubiquitination (Drosophila melanogaster)


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)


name: O-acetyl-L-serine + thiosulfate <=> acetate + H(+) + S-sulfo-L-cysteine


name: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+) => GDP-alpha-D-mannose + N,N'-diacetylchitobiosyl diphosphodolichol


name: MYO9B inactivates RHOA (Rattus norvegicus)


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Xenopus tropicalis)


name: a ganglioside GT1c + H(+) + UDP => a ganglioside GT2 + UDP-alpha-D-galactose


name: guanosine + NAD(+) => H(+) + N(2)-(ADP-D-ribosyl)-guanosine + nicotinamide


name: trehalose + H2O => 2 D-glucose (Homo sapiens)


name: beta-D-fructose 6-phosphate + diphosphate => beta-D-fructose 1,6-bisphosphate + H(+) + phosphate


name: 5-(methylsulfanyl)pentanenitrile + H(+) + sulfate + sulfur => (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate


name: p-6Y-VEGFR2 binds SH2D2A (Gallus gallus)


name: A + H2O + N-acetyl-L-cysteine => AH2 + N-acetyl-S-hydroxy-L-cysteine


name: p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Gallus gallus)


name: eNOS translocation from Golgi to Caveolae (Schizosaccharomyces pombe)


name: estrone 3-sulfate(out) + pentanoate(in) => estrone 3-sulfate(in) + pentanoate(out)


name: Recruitment of SYK to p-DAP12 (Gallus gallus)


name: H2O + mevastatin = H(+) + mevinic carboxylate


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-asparaginyl-[protein] => acetyl-CoA + N-terminal L-methionyl-L-asparaginyl-[protein]


name: (R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA = (R)-2-hydroxy-4-methylpentanoyl-CoA + 4-methylpentanoate


name: hydroxyacetone + NADP(+) => H(+) + methylglyoxal + NADPH


name: NTPDase4 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Xenopus tropicalis)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Mus musculus)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP => (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + UDP-alpha-D-glucuronate


name: (2E,6E)-farnesyl diphosphate = (+)-amorpha-4,11-diene + diphosphate


name: p-S54-PDE4B hydrolyses cAMP (Caenorhabditis elegans)


name: 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-homocysteine => L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-methionine


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Rattus norvegicus)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Caenorhabditis elegans)


name: H2O + NAD(+) + nitrite = H(+) + NADH + nitrate


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Rattus norvegicus)


name: H(+) + malonyl-CoA + triacontanoyl-CoA => 3-oxo-dotriacontanoyl-CoA + CO2 + CoA


name: (15Z)-tetracosenoyl-CoA + sphinganine = CoA + H(+) + N-(15Z-tetracosenoyl)-sphinganine


name: (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z,15Z)-hexadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: mast cell secretagogue receptor activity


name: Displacement of UNG glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: DLST transfers succinyl to CoA (Saccharomyces cerevisiae)


name: a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase


name: H2O2 + hydroxyhexadecanal => hexadecane-1,16-diol + O2


name: KDM1A is recruited to MYC and BCL2 genes (Gallus gallus)


name: 24-methylenecholesterol + UDP-alpha-D-glucose = 24-methylene cholesteryl beta-D-glucoside + H(+) + UDP


name: Proteolytic cleavage of complement factor C4 (Gallus gallus)


name: a dicarboxylate(in) + sulfate(out) = a dicarboxylate(out) + sulfate(in)


name: Activated FGFR3 phosphorylates FRS3 (Danio rerio)


name: CRYM reduces P2C to PPCA (Canis familiaris)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Schizosaccharomyces pombe)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 8 CO2 + 9 CoA + 7 H2O + 13 NADP(+) + wortmanamide B => 5-aminopentanoate + acetyl-CoA + 20 H(+) + 8 malonyl-CoA + 13 NADPH


name: CO2 + L-lyxonate => 2-carboxy-L-lyxonate + H(+)


name: beta-muricholate + deoxycholoyl-CoA = beta-muricholoyl-CoA + deoxycholate


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Danio rerio)


name: ORC6 translocates to the nucleus (Bos taurus)


name: 3 ATP <=> 2',3',3'-c-tri-AMP + 3 diphosphate


name: PGLYRP3,4 binds bacterial peptidoglycan (Homo sapiens)


name: MRN bound to shortened telomeres activates ATM (Homo sapiens)


name: glycerol-3-phosphate dehydrogenase (NAD+) activity


name: dimethylallyl diphosphate + siccayne = diphosphate + pestalodiol


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate <=> [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)


name: 3-dehydro-L-gulonate + NAD(+) = 2,3-dioxo-L-gulonate + H(+) + NADH


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Schizosaccharomyces pombe)


name: an aldehyde + H2O + NAD(+) <=> a carboxylate + 2 H(+) + NADH


name: 5-amino-6-(D-ribitylamino)uracil + riboflavin => 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+)


name: RFC binding displaces Pol Alpha on the C-strand of the telomere (Bos taurus)


name: MANBA hydrolyses GlcNAc:Man (Rattus norvegicus)


name: SUMOylation of HDAC1 with SUMO1 (Rattus norvegicus)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Saccharomyces cerevisiae)


name: p-3Y-SHC1 dissociates from IGF1R (Gallus gallus)


name: an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose => an alpha-D-mannosylinositol-1-phosphodihydroceramide + GDP + H(+)


name: H(+) + N(6)-methyladenosine in rRNA + S-adenosyl-L-homocysteine => adenosine in rRNA + S-adenosyl-L-methionine


name: PML binds RUNX1 (Drosophila melanogaster)


name: (Z)-dehydrocyclopeptine + 2-oxoglutarate + O2 <=> (-)-cyclopenine + CO2 + succinate


name: SIGMAR1 binds fluvoxamine (Homo sapiens)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Sus scrofa)


name: 5 AH2 + 2 H(+) + heme b + 4 O2 = 5 A + beta-staphylobilin + Fe(2+) + formaldehyde + 4 H2O


name: apo-[aequorin]--coelenterazine + O2 = [aequorin]


name: (15Z)-tetracosenoyl-CoA + sphing-4-enine => CoA + H(+) + N-(15Z-tetracosenoyl)-sphing-4-enine


name: Collagen type V degradation by MMP2,9,10 (Rattus norvegicus)


name: hypobromite + L-lysyl-[collagen] + L-methionyl-[collagen] <=> [collagen]-L-lysyl-N-S-L-methionyl-[collagen] + bromide + H(+) + H2O


name: 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oate + ATP + CoA <=> 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oyl-CoA + AMP + diphosphate


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)


name: ATP7A transports cytosolic Cu2+ to extracellular region (Rattus norvegicus)


name: butanoyl-CoA + H(+) + NADPH => butanal + CoA + NADP(+)


name: 1D-myo-inositol 5-phosphate + H2O => myo-inositol + phosphate


name: TLR processing at low pH (Canis familiaris)


name: CD22 binds B-cell receptor (Rattus norvegicus)


name: Beta-catenin migrates to the nucleus (Rattus norvegicus)


name: 5alpha-cholest-8-en-3beta-ol + NADP(+) <=> H(+) + NADPH + zymosterol


name: Methylthio-ribose-P = Methylthio-ribulose-P (Caenorhabditis elegans)


name: THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Homo sapiens)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Rattus norvegicus)


name: SUMOylation of DDX17 with SUMO1 (Xenopus tropicalis)


name: NEK9 phosphorylates NEK6/NEK7 (Canis familiaris)


name: Raf dimer inhibitors bind RAF heterodimers (Homo sapiens)


name: 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 2-heptanoyl-sn-glycero-3-phosphocholine => 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + hexanoyl-sn-glycero-3-phosphoethanolamine


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Drosophila melanogaster)


name: menadiol + 2 O2 => 2 H(+) + menadione + 2 superoxide


name: Phosphorylated Emi1 binds the beta-TrCP in the SCF complex (Xenopus tropicalis)


name: (9Z,12Z)-octadecadienoate + O2 = (8E,10R,12Z)-10-hydroperoxyoctadeca-8,12-dienoate


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Sus scrofa)


name: PXLP-K212-CTH cleaves L-Cystathionine (Dictyostelium discoideum)


name: a ganglioside GT1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1b (d18:1(4E)) + CMP + H(+)


name: VRK1/VRK2 phosphorylate BANF1 (Canis familiaris)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Danio rerio)


name: Metabotropic glutamate receptors bind glutamate (Drosophila melanogaster)


name: SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to PSMC6 (Homo sapiens)


name: alpha-D-glucose 1-phosphate + alpha-maltotriose => alpha-maltotetraose + phosphate


name: 5beta-dihydrotestosterone + H(+) + NADPH => 5beta-androstane-3beta,17beta-diol + NADP(+)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + 2 UDP-alpha-D-glucose => 2 H(+) + ternatin C5 + 2 UDP


name: PEX19 binds class I peroxisomal membrane proteins (Drosophila melanogaster)


name: GRB2-1:SOS1 binds p-3Y-SHC1 (Homo sapiens)


name: The phagophore extends from the PIP3-enriched structure (Saccharomyces cerevisiae)


name: 3,3',5-triiodo-L-thyronine + A + H(+) + iodide => AH2 + L-thyroxine


name: rifampicin ortho-naphthoquinone carboxamide => rifampicin para-naphthoquinone carboxamide


name: VD3 dissociates from GC (Rattus norvegicus)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Homo sapiens)


name: adenosine 3',5'-bisphosphate + H2O <=> AMP + phosphate


name: a monosaccharide 1-phosphate + H(+) + UTP => a UDP-monosaccharide + diphosphate


name: Necl-1:Nectin 3 trans heterodimer interaction (Rattus norvegicus)


name: PAPP-A2 proteolyzes IGF:IGFBP5:ALS (Homo sapiens)


name: H(+) + H2 + oxidized coenzyme F420-(gamma-L-Glu)(n) => reduced coenzyme F420-(gamma-L-Glu)(n)


name: Autophosphorylation of PTK2 at Y397 (Sus scrofa)


name: low-affinity basic amino acid transmembrane transporter activity


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol <=> a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester


name: malate dehydrogenase (decarboxylating) (NADP+) activity


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Dictyostelium discoideum)


name: H2O + L-seryl-tRNA(Lys) = L-serine + tRNA(Lys)


name: H2O + methanethiol + O2 = formaldehyde + H(+) + H2O2 + hydrogen sulfide


name: Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Canis familiaris)


name: 2-oxoglutarate + aculene D + O2 = aculene C + CO2 + H2O + succinate


name: acetyl-CoA + streptothricin F <=> CoA + H(+) + N(beta)-acetylstreptothricin F


name: 3-phenyllactate + NADP(+) <=> 3-phenylpyruvate + H(+) + NADPH


name: betaine aldehyde + H2O + O2 => glycine betaine + H(+) + H2O2


name: kaempferide + S-adenosyl-L-methionine = 7,4'-O-dimethylkaempferol + H(+) + S-adenosyl-L-homocysteine


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Drosophila melanogaster)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose = beta-D-Gal-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH = a long-chain fatty acid + n CO2 + (n+1) CoA + 2n NADP(+)


name: 2-aminobut-2-enoate + methanethiol => L-methionine


name: NADP(+) + scytalone <=> H(+) + NADPH + naphthalene-1,3,6,8-tetrol


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Caenorhabditis elegans)


name: Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Sus scrofa)


name: n H(+)(out) + serotonin(in) => n H(+)(in) + serotonin(out)


name: H2O + O-(ADP-D-ribosyl)-L-seryl-[protein] => ADP-D-ribose + L-seryl-[protein]


name: L-lysine + NADPH + O2 <=> H2O + N(6)-hydroxy-L-lysine + NADP(+)


name: CBL binds InlB-activated MET (Homo sapiens)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Xenopus tropicalis)


name: H(+) + isorhamnetin + S-adenosyl-L-homocysteine => quercetin + S-adenosyl-L-methionine


name: (2S)-2-isopropyl-3-oxosuccinate + H(+) => 4-methyl-2-oxopentanoate + CO2


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Caenorhabditis elegans)


name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Homo sapiens)


name: decanoyl-CoA + glycine <=> CoA + H(+) + N-decanoylglycine


name: DAG kinase produces phosphatidic acid from DAG (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O


name: ARV1 transports CHOL from ER membrane to plasma membrane (Bos taurus)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Danio rerio)


name: 2-oxoglutarate + mugineate + O2 = 3-epihydroxymugineate + CO2 + H(+) + succinate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + S-adenosyl-L-homocysteine


name: (3R)-[(10S)-11-epoxyfarnesyl]-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate + H(+) <=> asnovolin H


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Dictyostelium discoideum)


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Caenorhabditis elegans)


name: Syndecans 2, (4) bind TGFB1 (Mus musculus)


name: H2O + O2 + sarcosine <=> formaldehyde + glycine + H2O2


name: 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Gallus gallus)


name: ASC binds Caspase-8 complex (Rattus norvegicus)


name: ent-copalyl diphosphate => diphosphate + ent-sandaracopimara-8(14),15-diene


name: Phosphorylation of COP1 at Ser-387  by ATM (Canis familiaris)


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Danio rerio)


name: (8Z,11Z,14Z)-heptadecatrienal + CO2 + H2O => (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + H(+)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Danio rerio)


name: Oxidative demethylation of 3-meC damaged DNA By ALKBH3 (Homo sapiens)


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Bos taurus)


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Sus scrofa)


name: 1-hydroxy-6-methoxyphenazine + S-adenosyl-L-methionine = 1,6-dimethoxyphenazine + H(+) + S-adenosyl-L-homocysteine


name: Interaction of SOS with GRB2 bound to FADK1 (Sus scrofa)


name: HGFAC cleaves pro-HGF to form HGF dimer (Sus scrofa)


name: cyanate + 3 H(+) + hydrogencarbonate = 2 CO2 + NH4(+)


name: 2 H(+)(out) + L-alanyl-L-aspartate(out) <=> 2 H(+)(in) + L-alanyl-L-aspartate(in)


name: DHCR24 reduces LAN to 24,25-dhLAN (Sus scrofa)


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Canis familiaris)


name: a plastoquinone + H2O + L-arginine = 5-guanidino-2-oxopentanoate + a plastoquinol + NH4(+)


name: Prolactin receptor ligands bind the prolactin receptor (Canis familiaris)


name: (2R)-3-phosphoglycerate + 2-deoxy-alpha-D-ribose 1,5-bisphosphate + H(+) => (2R)-3-phospho-glyceroyl phosphate + 2-deoxy-alpha-D-ribose 1-phosphate


name: oxidoreductase activity, acting on metal ions, oxygen as acceptor


name: 1-docosanoylglycerol + H2O <=> docosanoate + glycerol + H(+)


name: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate


name: benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Rattus norvegicus)


name: Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (Xenopus tropicalis)


name: Conversion of Glycerol to Glycerol-3-phosphate (Xenopus tropicalis)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Caenorhabditis elegans)


name: GDP-alpha-D-mannose + H2O => D-mannose + GDP + H(+)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Xenopus tropicalis)


name: PRICKLE1 is degraded by the proteasome (Homo sapiens)


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2 <=> (1-deoxy-D-fructos-1-yl)amine + an aldehyde + H2O2


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Plasmodium falciparum)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Mus musculus)


name: H2O + S-methyl-thiohydantoin-5-propanoate => hydantoin-5-propanoate + methanethiol


name: Dissociation of insulin from insulin receptor (Rattus norvegicus)


name: acetyl-CoA + L-lysyl-[protein] <=> CoA + H(+) + N(6)-acetyl-L-lysyl-[protein]


name: S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: (S)-cis-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-1-hydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AKT phosphorylates MDM2 (Rattus norvegicus)


name: Two FPP molecules dimerize to form presqualene diphosphate (Saccharomyces cerevisiae)


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)


name: agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O = 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate


name: Formation of MHC II alpha beta heterodimer (Homo sapiens)


name: A + D-glucose => AH2 + D-glucono-1,5-lactone


name: 12-methyltridecanoate + ATP + CoA <=> 12-methyltridecanoyl-CoA + AMP + diphosphate


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Rattus norvegicus)


name: Expression of CCND1 is stimulated by CTNNB1:TCF4,LEF1 (Homo sapiens)


name: CARMA1 recruits MALT1 and BCL10 forming CBM Complex (Rattus norvegicus)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Mus musculus)


name: ID1 and ID3 gene expression (Homo sapiens)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH = isodeoxycholate + NADP(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-guanosine) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + O-phospho-L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + 2 phosphate


name: NEU3 cleaves GM3 to form LacCer (plasma membrane) (Canis familiaris)


name: (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine => ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine


name: acetate + 2 H(+) + NADPH => acetaldehyde + H2O + NADP(+)


name: 2-aminobut-2-enoate + L-cysteine => L,L-cystathionine


name: L-alanine + vanillin => pyruvate + vanillylamine


name: NEDD4L ubiquitinates SMAD2/3 (Drosophila melanogaster)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Plasmodium falciparum)


name: (1R,3R)-chrysanthemate + 2 H(+) + NADPH => (1R,3R)-chrysanthemal + H2O + NADP(+)


name: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + H(+)


name: RORA, EP300 bind CPT1A gene (Homo sapiens)


name: glycyl-L-proline(out) + H(+)(out) => glycyl-L-proline(in) + H(+)(in)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-galactose


name: (2E,6E)-farnesyl diphosphate + H2O <=> (2E,6E)-farnesol + diphosphate


name: MRN bound to shortened telomeres activates ATM (Gallus gallus)


name: METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Bos taurus)


name: HCCS inserts heme into cytochrome c (Caenorhabditis elegans)


name: A + a 3-oxo-5alpha-steroid = a 3-oxo-Delta(4)-steroid + AH2


name: 4 PBGs bind to form HMB (Rattus norvegicus)


name: an N-acylsphing-4-enine + UDP-alpha-D-galactose => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP


name: Keratan sulfate is cleaved from its proteoglycan by an unknown galactosidase (Homo sapiens)


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Mus musculus)


name: SCF-FBXL18 ubiquitinates FBXL7 (Sus scrofa)


name: ADP-1-deoxy-1,O(4)-didehydro-D-ribose + nicotinamide => NAD(+)


name: Bcl-2 and Bcl-XL bind NLRP1 (Danio rerio)


name: cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (22R)-hydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: Light stimulates opsin receptors (Xenopus tropicalis)


name: PDCD1 binds PDCD1 inhibitors (Sus scrofa)


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Mus musculus)


name: p-4Y-PLCG1 dissociates from activated FGFR1 (Gallus gallus)


name: a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + H2O <=> (2E,4S)-4,5-dihydroxypent-2-enal + a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H(+)


name: HEXA cleaves the terminal GalNAc from DS (Bos taurus)


name: sBAFF,sAPRIL binds TACI,BCMA (Canis familiaris)


name: 5' overhang single-stranded DNA endodeoxyribonuclease activity


name: N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate => H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH


name: H(+) + NADH + xanthommatin => 5,12-dihydroxanthommatin + NAD(+)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Schizosaccharomyces pombe)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Canis familiaris)


name: Activation of GIRK/Kir3 Channels (Gallus gallus)


name: CYTH proteins bind ARF1:GTP (Saccharomyces cerevisiae)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + H2O => 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + phosphate


name: TP53 stimulates ARID3A gene expression (Homo sapiens)


name: 3,4-dihydroxyphenylacetate + FMN + H(+) + H2O => 4-hydroxyphenylacetate + FMNH2 + O2


name: Interaction of PECAM-1 and SHP-2 (Canis familiaris)


name: L-arginyl-[protein] + 2 S-adenosyl-L-methionine => 2 H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O => a 5'-end phospho-ribonucleoside in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: 2 columbamine + O2 <=> 2 berberine + 2 H2O


name: RIPK1:RIPK3 oligomer binds MLKL (Rattus norvegicus)


name: estrone 3-sulfate(out) + pentanoate(in) = estrone 3-sulfate(in) + pentanoate(out)


name: OGFOD1:Fe2+ hydroxylates a proline residue of RPS23 (Mus musculus)


name: 2,3,6-trichlorohydroquinone + 2 glutathione => 2,6-dichlorohydroquinone + chloride + glutathione disulfide + H(+)


name: FOXM1 binds CDC25A promoter (Homo sapiens)


name: H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NADP(+) => (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADPH


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Gallus gallus)


name: The CDC25A gene transcription is stimulated by MYC and E2F1 and inhibited by the DREAM complex (Homo sapiens)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Mus musculus)


name: MDM2 translocates to the cytosol (Mus musculus)


name: 2-hexadecanoylglycerol + H2O <=> glycerol + H(+) + hexadecanoate


name: (9Z)-hexadecenoyl-[ACP] + L-lysyl-[protein] = H(+) + holo-[ACP] + N(6)-[(9Z)-hexadecenoyl]-L-lysyl-[protein]


name: 1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate


name: GSDMD (1-275) binds cardiolipin (Sus scrofa)


name: (12Z)-10-hydroxyoctadecenoate + H2O = 10,13-dihydroxyoctadecanoate


name: 2-methylbutanoate + ATP + CoA => 2-methylbutanoyl-CoA + AMP + diphosphate


name: 2-acyl LPI is acylated to PI by MBOAT7 (Saccharomyces cerevisiae)


name: H2O + N-acetyl-D-galactosamine + O2 = H(+) + H2O2 + N-acetyl-D-galactosaminate


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-phosphate + H2O => a 2'-deoxyribonucleoside + phosphate


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Bos taurus)


name: C30 botryococcene + diphosphate + NADP(+) = H(+) + NADPH + presqualene diphosphate


name: CDK1 phosphorylates MAPK6 (Mus musculus)


name: SEMA7A binds to integrin alpha1beta1 (Homo sapiens)


name: ATP + N-(hexanoyl)sphing-4-enine <=> ADP + H(+) + N-hexanoylsphing-4-enine 1-phosphate


name: CDC42 translocates to the endoplasmic reticulum membrane (Bos taurus)


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Bos taurus)


name: SL (surrogate light chain) binds IgH to form pre-BCR (Sus scrofa)


name: RHOT2 binds effectors at the mitochondrial outer membrane (Sus scrofa)


name: FMO1:FAD oxidizes HTAU to TAU (Bos taurus)


name: 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + thymol => gamma-terpinene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + H2O => 2-methylpropanoate + 2-oxopent-4-enoate + H(+)


name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Mus musculus)


name: Formation of the Spliceosomal P complex and exon ligation (Sus scrofa)


name: a fatty acid + sphing-4-enine => an N-acylsphing-4-enine + H2O


name: Recruitment of p190RhoGEF to p-FAK (Bos taurus)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Plasmodium falciparum)


name: coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine => coenzyme B + coenzyme M + methanophenazine


name: ZIP8 mediates zinc influx into cells (Rattus norvegicus)


name: D-methionine + pyruvate => 4-methylsulfanyl-2-oxobutanoate + L-alanine


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Mus musculus)


name: Phosphorylated STAT5 is released (Canis familiaris)


name: RHOG binds effectors at the plasma membrane (Rattus norvegicus)


name: 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) => 1-octadecanoyl-2-(15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: (2E,6E)-farnesyl diphosphate + H2O = (1S,6S,7R)-sesquipiperitol + diphosphate


name: Beta-catenin recruits CBP/p300 (Bos taurus)


name: (9Z)-octadecenoate + O2 <=> 10-hydroperoxy-(8E)-octadecenoate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 14,15-epoxy-(5Z,8Z,11Z,17Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADP(in) + FMN(out) => ADP(out) + FMN(in)


name: 4,5-dihydroxyphthalate + H(+) + NADH => cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+)


name: AH2 + ATP + 2 Co(II)-[methylamine-specific corrinoid protein] + H2O => A + ADP + 2 Co(I)-[methylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: Aquaporin-1 passively transports water into cell (Homo sapiens)


name: (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Bos taurus)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Danio rerio)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Gallus gallus)


name: RND1 binds effectors (Saccharomyces cerevisiae)


name: a short-chain fatty acyl-CoA + H2O <=> a short-chain fatty acid + CoA + H(+)


name: cytidine(out) + 2 Na(+)(out) <=> cytidine(in) + 2 Na(+)(in)


name: 2-nitrobutanedioate <=> fumarate + H(+) + nitrite


name: ATP + D-ribose 5-phosphate <=> ADP + alpha-D-ribose 1,5-bisphosphate + H(+)


name: CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin (Mus musculus)


name: acetyl phosphate + H(+) + sulfite <=> phosphate + sulfoacetaldehyde


name: morphine + NADP(+) <=> H(+) + morphinone + NADPH


name: NADPH + O2 + rifamycin SV => H2O + NADP(+) + rifamycin SV para-naphthoquinone carboxamide


name: Activated protein C:PROCR binds F2R (Homo sapiens)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Bos taurus)


name: Receptor CXCR6 binds CXCL16 ligand (Bos taurus)


name: ACER2 hydrolyzes ceramide (Golgi) (Caenorhabditis elegans)


name: p75NTR:NADE promotes caspase2/3 activation (Bos taurus)


name: H2O + NAD(+) + NH4(+) = 2 H(+) + hydroxylamine + NADH


name: [Pyr1]apelin-13 + H2O = [Pyr1]apelin-12 + L-phenylalanine


name: a ganglioside Ac-O-7-GD1a => a ganglioside Ac-O-8-GD1a


name: (+)-isomalbrancheamide B + bromide + FAD + 2 H(+) => (+)-isomalbrancheamide D + FADH2


name: 3-oxochola-1,4-dien-22-oate + H(+) + NADH + O2 <=> 9alpha-hydroxy-3-oxochola-1,4-dien-22-oate + H2O + NAD(+)


name: NFE2L2 binds the ME1 gene (Homo sapiens)


name: (2E)-butenoyl-CoA + (R)-carnitine <=> CoA + O-(2E)-butenoyl-(R)-carnitine


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Caenorhabditis elegans)


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Dictyostelium discoideum)


name: aklavinone + NADP(+) <=> aklaviketone + 2 H(+) + NADPH


name: spindle pole body-nuclear membrane anchor activity


name: Interaction of DAP12 and KIR2DS5 (Homo sapiens)


name: Interaction of MyoD:E protein with MEF2 (Bos taurus)


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Mus musculus)


name: 4-methylpentan-1-ol + NADP(+) = 4-methylpentanal + H(+) + NADPH


name: Formation of DSIF complex  (Saccharomyces cerevisiae)


name: Reduction of disulphide bonds in MHC II antigens (Bos taurus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Homo sapiens)


name: SFKs phosphorylate VAV2,3 (Rattus norvegicus)


name: 4-O-phospho-D-threonate + NAD(+) = 3-dehydro-4-O-phospho-L-erythronate + H(+) + NADH


name: H(+) + NADH + O2 + protoasukamycin <=> 4-hydroxyprotoasukamycin + H2O + NAD(+)


name: Recruitment of transition zone proteins (Gallus gallus)


name: Cross-linking of FCGRIA with IgG-coated Ag (Gallus gallus)


name: cyclolaudenol + H(+) + S-adenosyl-L-homocysteine => cycloartenol + S-adenosyl-L-methionine


name: DIMBOA beta-D-glucoside + H(+) + UDP => DIMBOA + UDP-alpha-D-glucose


name: 11-oxo-beta-amyrin + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = glycyrrhetinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: a ganglioside GD1c (d18:1(4E)) + CMP + H(+) => a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP-beta-L-colitose = alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP + H(+)


name: PAK1-3 dimer disassociates (Canis familiaris)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + 4 H2O + 6 oxidized [adrenodoxin] => 5beta-cholestane-3alpha,7alpha,12alpha-triol + 5 H(+) + 3 O2 + 6 reduced [adrenodoxin]


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Drosophila melanogaster)


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Rattus norvegicus)


name: CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene  (Sus scrofa)


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Bos taurus)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Bos taurus)


name: a 3',5'-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => a 5'-hydroxy-3'-methoxyflavone + S-adenosyl-L-methionine


name: Formation of RAD52 heptameric ring structure complexes (Canis familiaris)


name: CYLD deubiquitinates NEMO (Mus musculus)


name: acetylsalicylate + L-lysyl-[protein] = H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate


name: SCF-FBXL7 ubiquitinates AURKA (Mus musculus)


name: 15-methylhexadecasphing-4-enine + ATP => 15-methylhexadecasphing-4-enine 1-phosphate + ADP + H(+)


name: SPRY2 is serine phosphorylated in response to MAPK activation (Rattus norvegicus)


name: ATG12 binds ATG7 dimer (Dictyostelium discoideum)


name: 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2,3-di-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Sus scrofa)


name: TBK1 phosphorylates STAT6 at Ser407 (Bos taurus)


name: (4R)-hydroxysphinganine(in) + ATP + H2O => (4R)-hydroxysphinganine(out) + ADP + H(+) + phosphate


name: Recognition and Binding of Core Promoter Elements by TFIID (Saccharomyces cerevisiae)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Mus musculus)


name: (1'S)-averantin + O2 + reduced [NADPH--hemoprotein reductase] <=> (1'S,5'S)-5'-hydroxyaverantin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: intracellularly ATP-gated chloride channel activity


name: 6 AMP + corynebactin + 6 diphosphate + 3 H(+) + 3 H2O => 3 2,3-dihydroxybenzoate + 6 ATP + 3 glycine + 3 L-threonine


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Homo sapiens)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O


name: ARFGAPs stimulate ARF GTPase activity (Schizosaccharomyces pombe)


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Caenorhabditis elegans)


name: 3-oxoadipyl-CoA + H(+) + NADH => (3S)-3-hydroxyadipyl-CoA + NAD(+)


name: 2-acyl LPC is acylated to PC by LPCAT (Plasmodium falciparum)


name: Activated MAPK phosphorylates RAF1 (Plasmodium falciparum)


name: a diacylglycerol + a fatty acid + H(+) => a triacylglycerol + H2O


name: L-alanine(in) + L-cysteine(out) = L-alanine(out) + L-cysteine(in)


name: ADP + alpha-D-glucose 1-phosphate + H(+) = ADP-alpha-D-glucose + phosphate


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Danio rerio)


name: cordycepin + H(+) + H2O <=> 3'-deoxyinosine + NH4(+)


name: ADP + an acyl-CoA(in) + H(+) + phosphate => an acyl-CoA(out) + ATP + H2O


name: (9Z)-octadecenoyl-CoA + 1-dodecanoylglycerol <=> 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: L-phenylalanine + octadecanoate => H2O + N-octadecanoyl-L-phenylalanine


name: dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Rattus norvegicus)


name: RAC1:GTP binds NOX3 complex (Xenopus tropicalis)


name: 1-(3,4,5-trihydroxy-7-methoxynaphthalen-2-yl)propan-2-one + CO2 + NAD(+) => H(+) + NADH + O2 + toralactone


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Canis familiaris)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Danio rerio)


name: acetyl-CoA + an omega-(methylsulfanyl)-2-oxoalkanoate + H2O => a 2-(omega-methylsulfanyl)alkylmalate + CoA + H(+)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Xenopus tropicalis)


name: (5,6,15R)-trihydroxy-(7E,9E,11Z,13E,17Z)-eicosapentaenoate => (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + O2


name: Expression of IRX1 during nephron development (Homo sapiens)


name: HMGCR dimer binds statins (Canis familiaris)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Bos taurus)


name: MigFilin associates with Filamin and F-actin (Drosophila melanogaster)


name: H(+) + L-cystine + NADH => 2 L-cysteine + NAD(+)


name: oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor


name: Cinaciguat binds sGC:NO (Canis familiaris)


name: ALOX12 oxidises LTA4 to LXA4/B4 (Canis familiaris)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Canis familiaris)


name: PIAS1,2-1 SUMOylates AR with SUMO1 (Bos taurus)


name: TREM,CD300 binds lipids (Rattus norvegicus)


name: (S)-N-methylglaucine + H(+) + S-adenosyl-L-homocysteine => (S)-glaucine + S-adenosyl-L-methionine


name: p-S446-IRF5 dimer translocates to the nucleus (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 <=> (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2


name: SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ (Canis familiaris)


name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen (Gallus gallus)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Mus musculus)


name: VD3 translocates from extracellular region to ER membrane (Homo sapiens)


name: calcidiol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> calcitriol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: MITF-M dimer and TFAP2A bind the IRF4 gene (Homo sapiens)


name: L-aspartate(in) + L-phenylalanine(out) => L-aspartate(out) + L-phenylalanine(in)


name: SARS-CoV-2 gRNA complement (minus strand):RTC binds RTC inhibitors (Homo sapiens)


name: B-WICH recruits histone acetyltransferases (Sus scrofa)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate


name: G alpha (z) inhibits adenylate cyclase (Sus scrofa)


name: (S)-malate + NADP(+) = CO2 + NADPH + pyruvate


name: PKA phosphorylates RET:GDNF:GFRA dimer (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Danio rerio)


name: L-arginyl-[protein] + S-adenosyl-L-methionine => H(+) + N(5)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: a ubiquinol + 4 H(+)(out) + NAD(+) => a ubiquinone + 5 H(+)(in) + NADH


name: (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] => (1R,5S)-carveol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dephosphorylation of phospho-Cdh1 (Gallus gallus)


name: H2O + N-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> H(+) + N-(9Z-octadecenoyl) ethanolamine + sn-glycerol 3-phosphate


name: Binding of GRB2:GAB1 complex to p-EGFRvIII mutant (Homo sapiens)


name: SALMs1-3 bind each other in cis interactions (Gallus gallus)


name: CSNK1D phosphorylates SEC23 (Bos taurus)


name: (S)-(-)-citronellal + H(+) + NADH => (S)-(-)-citronellol + NAD(+)


name: SLC35D2 exchanges UDP-D-glucose for UMP (Sus scrofa)


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Bos taurus)


name: PP2A dephosphorylates p-RHO to RHO (Mus musculus)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Bos taurus)


name: Unknown kinase phosphorylates 9b (Homo sapiens)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Mus musculus)


name: Anti-MET small tyrosine kinase inhibitors bind MET (Homo sapiens)


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) <=> (6S)-5-formyl-5,6,7,8-tetrahydrofolate(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: ATP + phosphate + pyruvate => AMP + diphosphate + H(+) + phosphoenolpyruvate


name: a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base = a 1,3-diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base


name: aldehydo-N-acetyl-D-mannosamine + H2O + phosphoenolpyruvate => N-acetylneuraminate + phosphate


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Caenorhabditis elegans)


name: an archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate => an archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy- beta-D-glucuronosyl)-N-acetyl- alpha-D-glucosaminyl phosphate + H(+) + UDP


name: 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + 4-(2-aminophenyl)-2,4-dioxobutanoate


name: adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O + 4 L-glutamine <=> adenosylcob(III)yrate + 4 ADP + 4 H(+) + 4 L-glutamate + 4 phosphate


name: PXLP-K333-GADL1 decarboxylates acidic AAs (Homo sapiens)


name: p-S MAPK6,4 binds MAPKAPK5 (Rattus norvegicus)


name: Dissociation of  transcript with 5'-GMP from GT (Caenorhabditis elegans)


name: KSPG is secreted from the cell (Bos taurus)


name: L-threo-7,8-dihydrobiopterin + NADP(+) = H(+) + NADPH + sepiapterin


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ethanolamine + H(+) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + cholesterol => cholesteryl 3-beta-D-glucoside + N-hexadecanoylsphing-4-enine


name: galactarate => 5-dehydro-4-deoxy-D-glucarate + H2O


name: (E)-coniferaldehyde + H2O + NADP(+) = (E)-ferulate + 2 H(+) + NADPH


name: ATP + L-glutamate + L-glutamyl-[protein] => ADP + gamma-L-glutamyl-L-glutamyl-[protein] + H(+) + phosphate


name: H(+) + NADH + UDP-3-oxo-alpha-D-glucose => NAD(+) + UDP-alpha-D-glucose


name: p-ERK phosphorylates WAVEs and ABI (Mus musculus)


name: avenacoside B + H2O <=> 26-desgluco-avenacoside B + D-glucose


name: 1-O-(trans-sinapoyl)-beta-D-glucose + cyanidin 3-O-beta-D-glucoside = (E)-sinapate + cyanidin 3,5-di-O-beta-D-glucoside


name: "cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose)"


name: 3'-phosphoadenylyl sulfate + alpha-muricholate <=> adenosine 3',5'-bisphosphate + alpha-muricholate 7-sulfate + H(+)


name: NF-kB migrates to the nucleus and turns on transcription (Drosophila melanogaster)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Homo sapiens)


name: (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O => (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2


name: 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate => (R)-lactate + 2 Fe(III)-[cytochrome c]


name: Formation of cap binding complex (CBC) (Caenorhabditis elegans)


name: Abortive  termination of HIV-1 elongation after arrest (Tat-containing elongation complex) (Homo sapiens)


name: BIL dissociates from GSTA1, FABP1 (Xenopus tropicalis)


name: PRKAA2 regulated nuclear export of NFE2L2 (Caenorhabditis elegans)


name: 2-hydroxy-2,3-dihydrogenistein => genistein + H(+) + H2O


name: TBX5 and KAT5 bind the SRF gene (Homo sapiens)


name: N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyl,N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-homocysteine


name: (9Z)-octadecenamide + H2O <=> (9Z)-octadecenoate + NH4(+)


name: CDC42 translocates to the endoplasmic reticulum membrane (Schizosaccharomyces pombe)


name: 3'-phosphoadenylyl sulfate + glycocholate <=> adenosine 3',5'-bisphosphate + glycocholate 7-sulfate + H(+)


name: Calcium Binds Troponin-C (Gallus gallus)


name: an N-acetyl-L-cysteine-S-conjugate + H2O = acetate + an S-substituted L-cysteine


name: Abortive HIV-1 initiation after formation of the first phosphodiester bond (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: HTR3A antagonists bind HTR3A pentamer (Caenorhabditis elegans)


name: translation factor activity, RNA binding


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Caenorhabditis elegans)


name: FGF2:TGFBR3 binding to GIPC1 (Gallus gallus)


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Canis familiaris)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Drosophila melanogaster)


name: PRC1 SUMOylates CTBP1 with SUMO1 (Homo sapiens)


name: (2E)-hexenoyl-CoA + H2O => (3R)-hydroxyhexanoyl-CoA


name: an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA + H2O => a 2'-deoxyguanosine in DNA + H(+) + lactate


name: a 1,2-diacyl-sn-glycerol + CDP-ethanolamine <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: STAT3 is phosphorylated downstream of active ALK (Canis familiaris)


name: Ubiquitinated Cdc6 is degraded by the proteasome (Drosophila melanogaster)


name: glutamate:gamma-aminobutyric acid antiporter activity


name: Defective SLC35A3 does not exchange UDP-GlcNAc for UMP (Homo sapiens)


name: 18S-resolvin E2 + A + H2O => (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2


name: (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: Pellino binds hp-IRAK1:TRAF6 (Canis familiaris)


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Drosophila melanogaster)


name: UCHL5 binds INO80 complex (Canis familiaris)


name: Activated ATM phosphorylates ABL1 (Mus musculus)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Saccharomyces cerevisiae)


name: deoxycholate + FAD + H(+) + H2O = cholate + FADH2


name: H(+) + malonyl-CoA + triacontanoyl-CoA = 3-oxo-dotriacontanoyl-CoA + CO2 + CoA


name: ERBB3 binds neuregulins (Drosophila melanogaster)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O


name: The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)


name: (R)-3-amino-2-methylpropanoate + CO2 + NH4(+) => 3-(carbamoylamino)-2-methylpropanoate + 2 H(+) + H2O


name: RNLS:FAD oxidises dh-beta-NAD to NAD+ (Sus scrofa)


name: Cdc45 associates with the pre-replicative complex at the origin (Dictyostelium discoideum)


name: S-adenosyl-L-methionine + uridine(1498) in 16S rRNA => H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine


name: SMAD7 binds SERPINE1 gene promoter (Homo sapiens)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O => 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2


name: H2O + octadecanamide <=> NH4(+) + octadecanoate


name: ATP + domoate(in) + H2O = ADP + domoate(out) + H(+) + phosphate


name: L-isoleucine(in) + L-phenylalanine(out) => L-isoleucine(out) + L-phenylalanine(in)


name: CBL ubiquitinates FRS2 and FGFR1 (Xenopus tropicalis)


name: phosphate(in) + 2 thiosulfate(out) <=> phosphate(out) + 2 thiosulfate(in)


name: ESR1 binds ESR1 antagonists (Gallus gallus)


name: acetyl-CoA + AH2 + 3 malonyl-CoA + 3 S-adenosyl-L-methionine = A + 3 CO2 + 4 CoA + fumigermin + H2O + 3 S-adenosyl-L-homocysteine


name: NAD(+) + phloretate => (E)-4-coumarate + H(+) + NADH


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Danio rerio)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Canis familiaris)


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-retinylidene-N-retinylethanolamine = H2O + N-retinylidene-N-retinylphosphatidylethanolamine


name: (3R)-hydroxy-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA => (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H2O


name: STAT binds to the active receptor (Danio rerio)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[11-hydroxy-(9Z)-octadecenoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Rattus norvegicus)


name: INPP5E translocates to the primary cilium (Bos taurus)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Gallus gallus)


name: Acyl Ghrelin and C-Ghrelin are secreted (Homo sapiens)


name: BTN3A1 and BTN1A1 binds periplakin (PPL) (Bos taurus)


name: Prolactin receptor is internalized (Xenopus tropicalis)


name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate (Caenorhabditis elegans)


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Danio rerio)


name: Gs activation by prostacyclin receptor (Xenopus tropicalis)


name: 3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine + H2O <=> D-glucuronate + N(2),6-disulfo-D-glucosamine


name: beta-D-Gal-(1<->1')-Cer + CMP-N-acetyl-beta-neuraminate <=> CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Bos taurus)


name: translation repressor activity, non-nucleic acid binding


name: FAD attaches to SDHA (Rattus norvegicus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Schizosaccharomyces pombe)


name: 3-oxo-6-carboxyhexanoyl-[ACP] + CO2 + CoA => glutaryl-CoA + H(+) + malonyl-[ACP]


name: a uridine in mRNA => a pseudouridine in mRNA


name: 3 H(+) + NADPH + O2 + 2 rubrofusarin B => 2 H2O + NADP(+) + nigerone


name: (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)


name: CoA + N-acetyl-4-O-acetylneuraminate => acetyl-CoA + N-acetylneuraminate


name: PHF8 demethylates histone H4K20me1 (Drosophila melanogaster)


name: PIAS1 binds p-STAT1 dimer (Homo sapiens)


name: (+)-copalol + diphosphate => (+)-copalyl diphosphate + H2O


name: ALDH3A2-1 oxidises HD2NAL to PALM (Mus musculus)


name: H2O + N(1)-acetylspermine + O2 => 3-aminopropanal + H2O2 + N(1)-acetylspermidine


name: RBBP7 binds histone H3 (Dictyostelium discoideum)


name: Activated PLC gamma dissociates from the PDGF receptor (Mus musculus)


name: SH pentamer transports K+ (Homo sapiens)


name: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Mus musculus)


name: MASTL phosphorylates ENSA (Canis familiaris)


name: Caspase-mediated cleavage of Lamin A (Canis familiaris)


name: Spermine  => N-acetylated spermine (Homo sapiens)


name: Release of activated MAD2 from kinetochores (Gallus gallus)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Mus musculus)


name: beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol => cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine


name: a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose 6-phosphate + H(+) => a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate


name: ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)


name: 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + H(+) + NADPH => (5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP(+)


name: PEX19:class I PMP binds PEX3 (Dictyostelium discoideum)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Homo sapiens)


name: TBC1D10A binds JFC1 (Dictyostelium discoideum)


name: uridine(2604) in 23S rRNA = pseudouridine(2604) in 23S rRNA


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Saccharomyces cerevisiae)


name: a secondary alcohol + NAD(+) => a ketone + H(+) + NADH


name: SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate (Bos taurus)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Mus musculus)


name: 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA


name: a 5,6-dihydrouridine in mRNA + NADP(+) => a uridine in mRNA + H(+) + NADPH


name: palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity


name: The NODAL Receptor binds NODAL ligands (Homo sapiens)


name: ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine => ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate


name: Translocation of PDGF from ER to Golgi (Homo sapiens)


name: CYP11B2 oxidises 11DCORST to CORST (Canis familiaris)


name: 5-aminopentanamide + H2O => 5-aminopentanoate + NH4(+)


name: G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) (Homo sapiens)


name: acetyl-CoA + H(+) + malonyl-CoA => acetoacetyl-CoA + CO2 + CoA


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Gallus gallus)


name: H(+) + keto-D-fructose + NADH <=> D-sorbitol + NAD(+)


name: [(1->4)-alpha-D-glucosyl](n+1) + H(+) + UDP => [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose


name: (S)-2-amino-6-oxohexanoate + H2O2 + NH4(+) => H2O + L-lysine + O2


name: 2 H(+)(out) + L-aspartyl-glycine(out) => 2 H(+)(in) + L-aspartyl-glycine(in)


name: USP18 deubiquitinates TAK1:TAB1 (Gallus gallus)


name: GRB2:SOS1 binds to HBEGF:p-Y-EGFR (Homo sapiens)


name: Recognition and Binding of Core Promoter Elements by TFIID (Drosophila melanogaster)


name: NAD(+) + scyllo-inositol = H(+) + NADH + scyllo-inosose


name: "NAD(P)H sulfur oxidoreductase (CoA-dependent)"


name: TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 (Homo sapiens)


name: D-arabinose 1-dehydrogenase (NADP+) activity


name: D-arabinose + NADP(+) = D-arabinono-1,4-lactone + H(+) + NADPH


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-epicubenol + diphosphate


name: H2O + hexadecanoyl-CoA => adenosine 3',5'-bisphosphate + 2 H(+) + S-hexadecanoyl-4'-phosphopantetheine


name: RHOD translocates to the mitochondrial outer membrane (Danio rerio)


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Xenopus tropicalis)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Sus scrofa)


name: ADP + ATP + 2 H(+) => H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate


name: epidermal growth factor receptor activity


name: a triacylglycerol + all-trans-retinol => a 1,2-diacylglycerol + an all-trans-retinyl ester


name: Phosphorylation of pPTK2 by SRC (Mus musculus)


name: chloride(out) + 2 hydrogencarbonate(in) + Rb(+)(in) => chloride(in) + 2 hydrogencarbonate(out) + Rb(+)(out)


name: 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-(10Z-heptadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: NUMB:ITCH ubiquitinates GLI1 (Xenopus tropicalis)


name: Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)


name: 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Bos taurus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Canis familiaris)


name: 2-oxoglutarate + L-histidyl-[ribosomal protein uL15] + O2 => (3S)-3-hydroxy-L-histidyl-[ribosomal protein uL15] + CO2 + succinate


name: CoA + H(+) + N(6)-(2E)-butenoyl-L-lysyl-[protein] => (2E)-butenoyl-CoA + L-lysyl-[protein]


name: (9Z)-octadecenoyl-CoA + 1,2-dihexanoyl-sn-glycerol = 1,2-dihexanoyl-3-(9Z-octadecenoyl)-sn-glycerol + CoA


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + cholesterol <=> a 1-acyl-sn-glycero-3-phosphocholine + a cholesterol ester


name: 13(R)-HDPAn-3 translocates from endothelial cell to neutrophil (Homo sapiens)


name: diphosphate + syn-copalol => 9alpha-copalyl diphosphate + H2O


name: glutathione(in) + 3 Na(+)(in) => glutathione(out) + 3 Na(+)(out)


name: (2E)-tetradecenoyl-CoA + H2O => (3S)-hydroxytetradecanoyl-CoA


name: (9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: apo-UQCRFS1 binds LYRM7 (Canis familiaris)


name: Metabotropic glutamate receptors bind glutamate (Rattus norvegicus)


name: diphosphate + H(+) + N(6)-methyl-dAMP => H2O + N(6)-methyl-dATP


name: CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Homo sapiens)


name: 22-oxodocosanoate + H(+) + NADH => 22-hydroxydocosanoate + NAD(+)


name: deoxycholate + UDP-alpha-D-glucuronate <=> deoxycholoyl-24-O-(beta-D-glucuronate) + UDP


name: IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Homo sapiens)


name: ABP1 binds SHANK proteins (Caenorhabditis elegans)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(10Z,13Z,16Z)-docosatrienoyl-CoA + CO2 + CoA


name: 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+) => L-dopa + O2


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: USP4 deubiquitinate TRAF2,TRAF6 (Mus musculus)


name: AH2 + NH4(+) + sulfoacetaldehyde => A + H2O + taurine


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Danio rerio)


name: a 3-oxo-Delta(1)-steroid + AH2 => A + a 3-oxosteroid


name: PANK1/3 phosphorylate PanK (Drosophila melanogaster)


name: AP4 transports APP from trans-Golgi network to endosome lumen (Mus musculus)


name: acetyl-CoA + citramalate => (3S)-citramalyl-CoA + acetate


name: Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor (Bos taurus)


name: ATP + hydrogencarbonate + propanoyl-CoA = ADP + H(+) + methylmalonyl-CoA + phosphate


name: acetate + an aliphatic alcohol + H(+) => an acetyl ester + H2O


name: O-GlcNAcylation of RIPK3 (TLR4 signaling) (Mus musculus)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:GRB2-1:SOS1,phospho-VAV1 mediates exchange of GTP for GDP bound to RAS (Homo sapiens)


name: naphthalene-1,2-diol + O2 = 2-hydroxychromene-2-carboxylate + H(+)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Xenopus tropicalis)


name: 6-oxocampestanol + O2 + reduced [NADPH--hemoprotein reductase] = cathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RSF complex binds the centromere (Homo sapiens)


name: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit]


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: Intrinsic nucleotide exchange on RAS (Homo sapiens)


name: DNA polymerase epsilon binds at the origin (Xenopus tropicalis)


name: 3-dehydrocarnitine + H(+) + NADH => carnitine + NAD(+)


name: RhoGTPase GEF's recruited to DCC (Rattus norvegicus)


name: 3-oxododecanoate + CoA + H(+) => 3-oxododecanoyl-CoA + H2O


name: formaldehyde + glutathione => S-(hydroxymethyl)glutathione


name: ADP-Ribosylation of HNP-1 (Mus musculus)


name: Trimerization of cytosolic HSF1 (Gallus gallus)


name: Autocatalytic phosphorylation of FGFR4 (Caenorhabditis elegans)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Schizosaccharomyces pombe)


name: Fringe-modified Pre-NOTCH is cleaved by FURIN (Homo sapiens)


name: ZFP36L2 binds CNOT6L of CCR4-CNOT complex and an AU-rich element in mRNA (Homo sapiens)


name: DLAT trimer transfers acetyl to CoA (Saccharomyces cerevisiae)


name: H2O + UDP-alpha-D-glucose <=> alpha-D-glucose 1-phosphate + 2 H(+) + UMP


name: hyodeoxycholate + UDP-alpha-D-glucuronate = H(+) + hyodeoxycholate 6-O-(beta-D-glucuronate) + UDP


name: SLC24A1 exchanges 4Na+ for Ca2+, K+ (Homo sapiens)


name: NF-kB migrates to the nucleus and turns on transcription (Bos taurus)


name: H(+)(in) + phosphate(in) + sulfate(out) = H(+)(out) + phosphate(out) + sulfate(in)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)


name: p107 (RBL1) binds CyclinE/A:CDK2 (Dictyostelium discoideum)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + choline + H(+)


name: H2O + N(omega)-hydroxy-L-arginine <=> hydroxyurea + L-ornithine


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-N-(acetyl)-sphing-4-enine


name: isovitexin + O2 <=> 3''-dehydroisovitexin + H2O2


name: 5 (S)-methylmalonyl-CoA + a medium-chain fatty acyl-CoA + 32 H(+) + 5 malonyl-CoA + 22 NADPH <=> a mycoketide-CoA + 10 CO2 + 10 CoA + 11 H2O + 22 NADP(+)


name: D-dopachrome + H(+) => 5,6-dihydroxyindole + CO2


name: H(+) + NADH + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose <=> NAD(+) + UDP-2-acetamido-2,6-dideoxy-beta-L-talose


name: N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine => H(+) + phosphocholine + S-adenosyl-L-homocysteine


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + a 1-acyl-sn-glycero-3-phosphoethanolamine + H(+)


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Danio rerio)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Rattus norvegicus)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + methanol


name: (2E)-octenoyl-CoA + H2O2 => O2 + octanoyl-CoA


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Mus musculus)


name: CoA + dodecanoate + H(+) => dodecanoyl-CoA + H2O


name: Interleukin-27 binds Interleukin-27 receptor (Bos taurus)


name: H2O + NAD(+) + nonanal <=> 2 H(+) + NADH + nonanoate


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Bos taurus)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O <=> (14S,15S)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: GLA hydrolyzes PSAP(195-273):Gb3Cer:PE (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + 1-hexadecanoylglycerone 3-phosphate <=> 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate


name: ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+)


name: 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2 = 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Saccharomyces cerevisiae)


name: 3-oxochol-4-en-24-oyl-CoA + NAD(+) => 3-oxochol-4,6-dien-24-oyl-CoA + H(+) + NADH


name: Expression of EMX2 in the nephric duct (Homo sapiens)


name: Dehalogenation of carbon tetrachloride to form a free radical (Xenopus tropicalis)


name: VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Homo sapiens)


name: chrysoeriol + H(+) + S-adenosyl-L-homocysteine => luteolin + S-adenosyl-L-methionine


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Schizosaccharomyces pombe)


name: LGI2 binds ADAM22,23 (Xenopus tropicalis)


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) <=> 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADH


name: H antigen-sec translocates from Golgi lumen to extracellular region (Homo sapiens)


name: ATP + CoA + sulfoacetate => ADP + phosphate + sulfoacetyl-CoA


name: USP9X (FAM) deubiquitinates SMAD4 (Mus musculus)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Canis familiaris)


name: ATP + CoA + tetracosanoate = AMP + diphosphate + tetracosanoyl-CoA


name: 20S,25-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin] => 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: H2O + NADP(+) + protoviolaceinate => H(+) + NADPH + O2 + protodeoxyviolaceinate


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Gallus gallus)


name: Surface deployment of platelet dense granule membrane components (Xenopus tropicalis)


name: 1D-myo-inositol hexakisphosphate + H2O <=> 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + phosphate


name: UBA1 adenylates ubiquitin in the cytosol (Caenorhabditis elegans)


name: desmethylnectriapyrone + S-adenosyl-L-methionine => H(+) + nectriapyrone + S-adenosyl-L-homocysteine


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose => an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP + H(+)


name: RHAG transports CO2 from cytosol to extracellular region (Rattus norvegicus)


name: (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase] => (1R,6S)-isopiperitenol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Sus scrofa)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Drosophila melanogaster)


name: CDK5 phosphorylates DARPP-32 on Thr75 (Bos taurus)


name: MET phosphorylates GAB1 (Canis familiaris)


name: alpha-ribazole 5'-phosphate + H2O <=> alpha-ribazole + phosphate


name: (indol-3-yl)acetonitrile + H2O => (E)-(indol-3-yl)acetaldehyde oxime


name: cis,trans-4-hydroxymuconate semialdehyde + H2O + NAD(+) <=> 2 H(+) + maleylacetate + NADH


name: alpha-D-galactose 1-phosphate + H2O => D-galactose + phosphate


name: 2'-deoxymugineate + 2-oxoglutarate + O2 => 3-epihydroxy-2'-deoxymugineate + CO2 + H(+) + succinate


name: H2O + sucrose 6(F)-phosphate = phosphate + sucrose


name: CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 (Danio rerio)


name: (2E)-tetradecenedioyl-CoA + H2O2 => O2 + tetradecanedioyl-CoA


name: (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA


name: docosanoyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> AMP + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + H(+)


name: L-threonyl-[protein] + phosphate => H2O + O-phospho-L-threonyl-[protein]


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Drosophila melanogaster)


name: RNA 2',3'-cyclic 3'-phosphodiesterase activity


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Mus musculus)


name: NTPDase4 hydrolyzes nucleoside triphosphates (Rattus norvegicus)


name: H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-(methylsulfanyl)propylamine


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Xenopus tropicalis)


name: Active ALK phosphorylates SHC1 (Homo sapiens)


name: Factor D cleaves C3(H2O)-bound Factor B (Canis familiaris)


name: (S)-2-methyl-3-oxopropanoate + H2O + NAD(+) <=> 2 H(+) + methylmalonate + NADH


name: SCF(SKP2) polyubiquitinates RUNX2 (Caenorhabditis elegans)


name: USP19 deubiquitinates RNF123 (Bos taurus)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Sus scrofa)


name: Binding of ADAR1 homodimer to dsRNA duplex (Gallus gallus)


name: RHOF GAPs stimulate RHOF GTPase activity (Rattus norvegicus)


name: SUMOylation of PML with SUMO3 (Danio rerio)


name: an oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O => an N-acyl-sphingoid base + an oligoglycosyl-(1->4)-D-glucose


name: IL6R gene expression is enhanced by CEBPA (Homo sapiens)


name: 1-octadecanoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoserine + 9,10-epoxyoctadecanoate + H(+)


name: 3-phenylpropanal + hydrogen cyanide = (2S)-2-hydroxy-4-phenylbutanenitrile


name: phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Xenopus tropicalis)


name: KAT6A, KAT6B-containing ING5 complexes acetylate replicative histone H3 (Canis familiaris)


name: KIBRA (WWC1) binds LATS proteins (Homo sapiens)


name: RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc (Bos taurus)


name: COPI vesicle uncoating at the ER (Rattus norvegicus)


name: Calmodulin activates Cam-PDE 1 (Dictyostelium discoideum)


name: 4-hydroxybenzoate + CoA + H(+) => 4-hydroxybenzoyl-CoA + H2O


name: guanosine(2553) in 23S rRNA + S-adenosyl-L-methionine => 2'-O-methylguanosine(2553) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Mus musculus)


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Gallus gallus)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Danio rerio)


name: H2O + oxaloacetate + propanoyl-CoA <=> 2-methylcitrate + CoA + H(+)


name: (9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphocholine = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: DNA polymerase alpha:primase binds at the origin (Drosophila melanogaster)


name: SUMOylation of NCOA1 with SUMO1 (Sus scrofa)


name: NEK6/NEK7 phosphorylates NUP98 (Bos taurus)


name: ATP + propanoate <=> ADP + propanoyl phosphate


name: cyclic (2R)-2,3-bisphosphoglycerate + H2O => (2R)-2,3-bisphosphoglycerate + 2 H(+)


name: Recruitment of SYK to p-DAP12 (Sus scrofa)


name: EPH:EFN dimers tetramerise (Xenopus tropicalis)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Xenopus tropicalis)


name: 4-hydroxybenzoate + ATP + holo-[4-hydroxyphenylalkanoate synthase] => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + diphosphate


name: Elongation of Extended Telomeric Chromosome End (Sus scrofa)


name: 2-sulfenohercynine + NH4(+) + pyruvate => H2O + S-(hercyn-2-yl)-L-cysteine S-oxide


name: Activated MET recruits GRB2-1:SOS1 (Rattus norvegicus)


name: 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2 reduced [2Fe-2S]-[ferredoxin] => [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine


name: AKR1B1 reduces Glc to D-sorbitol (Saccharomyces cerevisiae)


name: RHOA binds effectors at the plasma membrane (Homo sapiens)


name: 2-hydroxyethane-1-sulfonate(out) + Na(+)(out) <=> 2-hydroxyethane-1-sulfonate(in) + Na(+)(in)


name: A + chloride + chloroethene + H(+) => (Z)-1,2-dichloroethene + AH2


name: PP2A dephosphorylates KSR1 (Mus musculus)


name: NAD-dependent protein lysine deacetylase activity


name: H2O + L-prolinylglycine = glycine + L-proline


name: USP9X (FAM) deubiquitinates SMAD4 (Homo sapiens)


name: H(+) + L-serine + tetradecanoyl-CoA => 3-oxohexadecasphinganine + CO2 + CoA


name: GPCR neuropeptide receptor binds neuropeptides B and W (Mus musculus)


name: cholesteryl 3-beta-D-galactoside + N-dodecanoylsphing-4-enine => 1-(beta-D-galactosyl)-N-dodecanoylsphing-4-enine + cholesterol


name: glutathione-disulfide reductase (NADPH) activity


name: 1,5-anhydro-D-fructose => ascopyrone M + H2O


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Mus musculus)


name: CHUK, IKBKB phosphorylate CYLD at S418 (Drosophila melanogaster)


name: guanine(out) + Na(+)(out) <=> guanine(in) + Na(+)(in)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Sus scrofa)


name: OSM binds LIFR:JAKs,OSMR:JAKs (Rattus norvegicus)


name: a phenol + acetate + H(+) => a phenyl acetate + H2O


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Bos taurus)


name: Translocation of BMF to mitochondria (Bos taurus)


name: all-trans-heptaprenyl diphosphate => (R)-tetraprenyl-beta-curcumene + diphosphate


name: Phosphorylation of STAT1 by JAK kinases (Sus scrofa)


name: Fall Back to Closed Pre-initiation Complex (Rattus norvegicus)


name: ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex (Homo sapiens)


name: 2 2-oxoglutarate + 2 O2 + pentalenolactone D = 2 CO2 + H2O + pentalenolactone F + 2 succinate


name: Surface deployment of platelet alpha granule membrane components (Xenopus tropicalis)


name: amide transmembrane transporter activity


name: H(+) + loliose + UDP => sucrose + UDP-alpha-D-galactose


name: glycochenodeoxycholate(out) + 2 Na(+)(out) = glycochenodeoxycholate(in) + 2 Na(+)(in)


name: 5,6-dihydrouracil + H2O => 3-(carbamoylamino)propanoate + H(+)


name: SRD5A1 dehydrogenates TEST to DHTEST (Bos taurus)


name: (S)-8-oxocitronellyl enol => cis-cis-nepetalactol


name: H(+)(out) + L-methionine(in) = H(+)(in) + L-methionine(out)


name: FAHD1 dimer hydrolyses OA to PYR (Mus musculus)


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Sus scrofa)


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA => (2E,15Z,18Z,21Z,24Z)-triacontapentaenoyl-CoA + H2O


name: RBBP7 binds histone H3 (Plasmodium falciparum)


name: CYP19A1 hydroxylates TEST to EST17b (Xenopus tropicalis)


name: PI3 binds the bacterial surface (Homo sapiens)


name: Lysosomal degradation of gap junction plaques (Caenorhabditis elegans)


name: S1P binds S1PR3 in response to E2 stimulation (Rattus norvegicus)


name: H2O + O2 + serotonin = (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4(+)


name: NPAS4 translocates to the cytosol (Homo sapiens)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Canis familiaris)


name: H(+)(in) + tetracycline(out) => H(+)(out) + tetracycline(in)


name: dinoflagellate luciferin + O2 = H(+) + H2O + hnu + oxidized dinoflagellate luciferin


name: H(+)(out) + lactose(in) <=> H(+)(in) + lactose(out)


name: PGH2 is isomerised to PGE2 by PTGES (Canis familiaris)


name: SERPINA5 binds activated protein C (Rattus norvegicus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: NTPDase1 hydrolyzes nucleoside triphosphates (Canis familiaris)


name: SPRY2 translocates to the plasma membrane (Danio rerio)


name: Syndecans 2, (4) bind TGFB1 (Bos taurus)


name: 3-hydroxy-3-(4-hydroxyphenyl)propanoate = 4-hydroxybenzaldehyde + acetate


name: H2O + O-phospho-L-serine <=> L-serine + phosphate


name: Removal of siRNA passenger strand (Rattus norvegicus)


name: adenosine 3',5'-bisphosphate(in) + NAD(+)(out) => adenosine 3',5'-bisphosphate(out) + NAD(+)(in)


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Rattus norvegicus)


name: PELI1 binds activated RIPK1:RIPK3 (Canis familiaris)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Mus musculus)


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: Regulation of KIF23 (MKLP1) by phosphorylation (Xenopus tropicalis)


name: L-arogenate + NADP(+) = CO2 + L-tyrosine + NADPH


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycerol <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol


name: 3,3',5'-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) => 3,3',5'-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: DUX4, TPRXL, TPRX1, and TPRX2 bind the DUXB gene (Homo sapiens)


name: Activation of Potassium transport channels (Homo sapiens)


name: (2R,3R)-tartrate(out) + succinate(in) => (2R,3R)-tartrate(in) + succinate(out)


name: (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B + H2O => [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => (+)-penichrysol + diphosphate


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-tetracosanoylsphinganine = a 1,2-diacyl-sn-glycerol + N-tetracosanoylsphinganine-(1D-myo-inositol)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Xenopus tropicalis)


name: OPLAH hydrolyses OPRO to L-Glu (Dictyostelium discoideum)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Rattus norvegicus)


name: acetyl-[citrate lyase ACP] + H2O => acetate + H(+) + holo-[citrate lyase ACP]


name: a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate <=> 15-cis-phytoene + 2 diphosphate


name: Trimerization of the FASL:FAS receptor complex (Canis familiaris)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O


name: Autophosphorylation of LYN kinase (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate = delta-cadinene + diphosphate


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Xenopus tropicalis)


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Xenopus tropicalis)


name: 4-O-demethylbarbatate + S-adenosyl-L-methionine = proatranorin I + S-adenosyl-L-homocysteine


name: ATM recognizes H2AFX-Nucleosomes (Saccharomyces cerevisiae)


name: EGFRvIII cancer variant does not bind EGF ligand (Homo sapiens)


name: 2-oxoglutarate + gibberellin A12 aldehyde + O2 => CO2 + gibberellin A12 + H(+) + succinate


name: 3-phenylpyruvate + CO2 + H2O => H(+) + prephenate


name: CDK1 phosphorylates LBR (Canis familiaris)


name: IL1F10 binds IL1RAPL1 (Canis familiaris)


name: 2 L-ascorbate + N-(9Z-octadecenoyl)glycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-(9Z-octadecenoyl)-(2S)-hydroxyglycine


name: Unwinding DNA for the nascent transcript (Xenopus tropicalis)


name: (R)-nicotine + A + H2O <=> (R)-6-hydroxynicotine + AH2


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + pentadecanoyl-CoA <=> 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Bos taurus)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Bos taurus)


name: STAT1 and STAT3 dimers translocate to the nucleus (Bos taurus)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Xenopus tropicalis)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Saccharomyces cerevisiae)


name: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate


name: D-glyceraldehyde 3-phosphate + H2O + NADP(+) <=> (2R)-3-phosphoglycerate + 2 H(+) + NADPH


name: ATP + cytidine 5'-diphosphoramidate <=> ADP + cytidine 3'-phospho-5'-diphosphoramidate + H(+)


name: 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) => 8-epi-inunolide + H2O


name: Formation of Elongin complex (Sus scrofa)


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Homo sapiens)


name: Phosphorylation of IL2RB Y338 enables SHC recruitment (Mus musculus)


name: E2F6:TFDP1:EPC1 binds the PRC2 complex (Canis familiaris)


name: transmembrane receptor protein tyrosine phosphatase activity


name: MSH2:MSH6 exchanges ADP for ATP (Dictyostelium discoideum)


name: cathasterone + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + teasterone


name: A + L-pipecolate => AH2 + H(+) + L-1-piperideine-6-carboxylate


name: MAVS:TOMM70 recruits HSP90:TBK1:IRF3 (Homo sapiens)


name: a 3beta-hydroxysteroid-4alpha-carboxylate + NADP(+) = a 3-oxosteroid + CO2 + NADPH


name: ACP-dependent peptidyl-lysine N6-myristoyltransferase activity


name: L-lysyl-[protein] + tetradecanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-tetradecanoyl-L-lysyl-[protein]


name: Factor B binds to C3(H2O) (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: TBC1D10A (EPI64) binds ARF6:GTP (Gallus gallus)


name: PTPN7 binds p-T,Y-MAPK (Drosophila melanogaster)


name: DEGS2 oxygenates dihydroceramide (Sus scrofa)


name: Trimmed spike protein binds to calnexin (Homo sapiens)


name: MIR206 microRNA binds 3'UTR of NOTCH3 mRNA (Homo sapiens)


name: 2',3'-cyclophospho-UMP + H2O => 3'-UMP + H(+)


name: Exchange of oxygen with sulfur in MoCo (Rattus norvegicus)


name: a rhodoquinone + succinate <=> a rhodoquinol + fumarate


name: IL34 dimer:SDC1 binds CSF1R (Gallus gallus)


name: protein-arginine omega-N asymmetric methyltransferase activity


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1alpha (d18:1(4E)) + CMP + H(+)


name: PTPN18 binds ERBB2:EGFR heterodimers (Mus musculus)


name: 2 gamma-L-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH


name: RUNX1 binds the SWI/SNF complex (Canis familiaris)


name: 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate => 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Homo sapiens)


name: "phosphogluconate dehydrogenase [NAD(P)(+)-dependent, decarboxylating]"


name: UVSSA:USP7 deubiquitinates ERCC6 (Xenopus tropicalis)


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Canis familiaris)


name: protein transmembrane transporter activity


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Homo sapiens)


name: 4 (S)-methylmalonyl-CoA + 4-nitrobenzoyl-CoA + 8 H(+) + malonyl-CoA + 4 NADPH <=> 5 CO2 + 6 CoA + demethylluteothin + 3 H2O + 4 NADP(+)


name: p-S207 KARS1 dimer translocates to the nucleus (Homo sapiens)


name: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+) => H2O + progoitrin


name: Interaction of NUMB with L1 (Xenopus tropicalis)


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Caenorhabditis elegans)


name: (1S,2R,4R)-neoisodihydrocarveol + NAD(+) => (1S,4R)-isodihydrocarvone + H(+) + NADH


name: lysophosphatidic acid phosphatase activity


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Canis familiaris)


name: Isomerization of GlcNAc6P to GlcNAc1P (Rattus norvegicus)


name: 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na(+)(out) => 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na(+)(in)


name: Active ALK phosphorylates SHC1 (Canis familiaris)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Sus scrofa)


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] => 2-hydroxy-2,3-dihydrogenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + methyl acetate + NADP(+) => acetone + H(+) + NADPH + O2


name: BTK in G alpha (12)-BTK complex is activated (Rattus norvegicus)


name: ADP-D-ribose + H(+) + L-glutamyl-[protein] => 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O


name: an aliphatic alcohol + butanoate + H(+) => a butanoate ester + H2O


name: STAT1 and STAT3 dimers translocate to the nucleus (Gallus gallus)


name: UDP-glucose is oxidised to UDP-glucuronate (Sus scrofa)


name: cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + H2O => (S)-2-hydroxypropylphosphonate + CMP + H(+)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Mus musculus)


name: anthranilate + 3 H(+) + NADPH + O2 => catechol + CO2 + NADP(+) + NH4(+)


name: AH2 + cholesterol + O2 <=> 25-hydroxycholesterol + A + H2O


name: dodecanal + H2O + O2 <=> dodecanoate + H(+) + H2O2


name: Phosphorylated RHOU translocates to the endosome membrane (Schizosaccharomyces pombe)


name: Expression of APOD regulated by NR1H2 or NR1H3 (Homo sapiens)


name: RHOD translocates to the mitochondrial outer membrane (Xenopus tropicalis)


name: (6-hydroxyhexanoyl)n + H2O => (6-hydroxyhexanoyl)n-1 + 6-hydroxyhexanoate + H(+)