name: H(+) + hexadecanoate + hnu => CO2 + pentadecane


name: GLB1 hydrolyzes SapB/C:LacCer (Drosophila melanogaster)


name: Persulfide sulfur is dioxygenated (Xenopus tropicalis)


name: a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1b + CMP + H(+)


name: PIDD1 associates with CRADD (Canis familiaris)


name: Nephrin trans-homophilic interaction (Rattus norvegicus)


name: androst-4-ene-3,11,17-trione + H(+) + NADPH = 17beta-hydroxyandrost-4-ene-3,11-dione + NADP(+)


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Canis familiaris)


name: [thioredoxin]-dithiol + glycine + H(+) + phosphate => [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Bos taurus)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Xenopus tropicalis)


name: 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: 2 H(+)(in) + L-aspartate(in) => 2 H(+)(out) + L-aspartate(out)


name: PEBP1 binds activated RAF1 (Drosophila melanogaster)


name: FAD + H(+) + undecanoyl-CoA => FADH2 + trans-2-undecenoyl-CoA


name: Binding of Syk tyrosine kinase (Xenopus tropicalis)


name: Dentin matrix protein 1 binds integrin alphaVbeta3 (Bos taurus)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Rattus norvegicus)


name: 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA => CoA + H(+) + mycothiol


name: H2O + sucrose 6(F)-phosphate <=> phosphate + sucrose


name: Autoubiquitination of phospho-COP1(Ser-387 ) (Rattus norvegicus)


name: SLC22A1 transports Cipro into renal cell (Xenopus tropicalis)


name: CMP-5'-(3-amino-3-carboxypropyl)phosphonate + H(+) = CMP-5'-(3-aminopropyl)phosphonate + CO2


name: CHEK2 phosphorylates BRCA1 (Mus musculus)


name: H2O + N-[(S)-lactoyl]-L-phenylalanine => (S)-lactate + L-phenylalanine


name: urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR (Canis familiaris)


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA <=> an acyl-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + holo-[ACP]


name: TP53 binds the STEAP3 gene (Homo sapiens)


name: SUMOylation of NPM1 with SUMO2,3 (Homo sapiens)


name: 11,20-dihydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 11-hydroxyferruginol + O2 + reduced [NADPH--hemoprotein reductase]


name: RFC dissociates after sliding clamp formation (Homo sapiens)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Mus musculus)


name: DLAT trimer transfers acetyl to CoA (Canis familiaris)


name: L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] = atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-hydroxyestrone + NH4(+) + O2 = 2 H(+) + 2 H2O + pyridinestrone carboxylate


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Sus scrofa)


name: KDM5A-D demethylate Me2K5-histone H3 (Bos taurus)


name: RHOA:GTP translocates to the ER membrane (Canis familiaris)


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Bos taurus)


name: 3-oxotetracosanoyl-CoA + H(+) + NADPH <=> (3R)-hydroxytetracosanoyl-CoA + NADP(+)


name: ITPA dimer dephosphorylates RBV-TP to RBV-MP (Sus scrofa)


name: Formation of HIF:CBP:p300 complex at promoters (Homo sapiens)


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Sus scrofa)


name: GTP + H2O = guanosine + H(+) + triphosphate


name: 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 = 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H(+) + H2O2


name: VEGFR2 autophosphorylates (Homo sapiens)


name: 5-deoxy-5-amino-3-dehydroshikimate => 3-amino-5-hydroxybenzoate + H(+) + H2O


name: a phenyl acetate + H2O <=> a phenol + acetate + H(+)


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Rattus norvegicus)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Mus musculus)


name: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) => 7,8-dihydroxykynurenate + H(+) + NADH


name: (2S)-3-sulfolactaldehyde + H2O + NADP(+) <=> (2S)-3-sulfolactate + 2 H(+) + NADPH


name: D-xylulose 1,5-bisphosphate + H2O = D-xylulose 5-phosphate + phosphate


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ATP + H2O => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ADP + H(+) + phosphate


name: alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+) => GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate


name: 1-O-alkyl-sn-glycerol + H(+) + phosphocholine => 1-O-alkyl-sn-glycero-3-phosphocholine + H2O


name: COX15 transforms heme O to heme A (Drosophila melanogaster)


name: nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Mus musculus)


name: ATRX:DAXX binds to subtelomeric chromosomal regions (Mus musculus)


name: beta-cryptoxanthin + O2 => (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Mus musculus)


name: lithocholate + NADP(+) = 3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: PTPS is phosphorylated by cGMP-dependant protein kinase II (Mus musculus)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Caenorhabditis elegans)


name: Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1) (Danio rerio)


name: 3'-phosphoadenylyl sulfate + estrone => adenosine 3',5'-bisphosphate + estrone 3-sulfate + H(+)


name: Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Homo sapiens)


name: L-Glutamine transport into neurons (Gallus gallus)


name: PRKN polyubiquitinates RIPK3 (Homo sapiens)


name: precorrin-5 + S-adenosyl-L-homocysteine => precorrin-4 + S-adenosyl-L-methionine


name: Expression of Lipoprotein lipase (LPL) (Homo sapiens)


name: (R)-lactate(in) + citrate(out) <=> (R)-lactate(out) + citrate(in)


name: LDLR is bound by DAB2 and ARH (Bos taurus)


name: H(+) + 2 L-arginine + 3 NADH + 4 O2 => 4 H2O + 2 L-citrulline + 3 NAD(+) + 2 nitric oxide


name: MFSD2A transports LPC from extracellular region to plasma membrane (Dictyostelium discoideum)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Bos taurus)


name: hydroxymethylfurfural reductase (NADPH) activity


name: 2 cob(II)inamide-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] => 2 cob(I)inamide-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein]


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Danio rerio)


name: [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)


name: 6-deoxoteasterone + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydro-6-deoxoteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-oxooctadecanoyl-CoA + H(+) + NADPH => 3-hydroxyoctadecanoyl-CoA + NADP(+)


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + ADP + H(+) => 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + ATP


name: ZFPM proteins bind GATA proteins (Drosophila melanogaster)


name: carcinine + H(+) + holo-[peptidyl-carrier protein] => beta-alanyl-[peptidyl-carrier protein] + histamine


name: N(4)-aminopropylspermidine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + N(4)-bis(aminopropyl)spermidine + S-methyl-5'-thioadenosine


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Xenopus tropicalis)


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Schizosaccharomyces pombe)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Mus musculus)


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Xenopus tropicalis)


name: 17beta-estradiol + AH2 + O2 => 6beta-hydroxyestradiol-17beta + A + H2O


name: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) <=> 3,4-dihydroxybenzoate + CO2 + NADH


name: GDP-beta-L-galactose + phosphate <=> beta-L-galactose 1-phosphate + GDP + H(+)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Bos taurus)


name: Translocation of DFF to the nucleus (Bos taurus)


name: Exocytosis of azurophil granule membrane proteins (Gallus gallus)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Bos taurus)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Gallus gallus)


name: p115-RhoGEF activation of RHOA (Mus musculus)


name: APS is phosphorylated to PAPS (Mycobacterium tuberculosis)


name: 2-oxoglutarate + [ribosomal protein uS12]-L-proline + O2 => [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + CO2 + succinate


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Dictyostelium discoideum)


name: a fatty acid + sphinganine => an N-acylsphinganine + H2O


name: ING2 binds PI5P (Saccharomyces cerevisiae)


name: 3-(all-trans-decaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = 2-methoxy-6-(all-trans-decaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: TRADD:TRAF2:RIP1 complex binds FADD (Sus scrofa)


name: Expression of CXCR4 in definitive endoderm (Homo sapiens)


name: Caspase-7 translocates to the nucleus (Sus scrofa)


name: (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O = 18S-resolvin E1


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Xenopus tropicalis)


name: Inactivation of APC/C via CDC20 sequestration (Homo sapiens)


name: cytidine(34) in tRNA precursor + S-adenosyl-L-methionine => 5-methylcytidine(34) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Plasmodium falciparum)


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Bos taurus)


name: 3,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Danio rerio)


name: Duplex miRNA is loaded into Argonaute (Xenopus tropicalis)


name: (9Z)-tetradecenoate + CoA + H(+) => (9Z)-tetradecenoyl-CoA + H2O


name: 5,10-methylenetetrahydromethanopterin + NAD(+) <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Xenopus tropicalis)


name: a 3'-end uridylyl-uridine-RNA <=> a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Xenopus tropicalis)


name: adenosine(1618) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(1618) in 23S rRNA + S-adenosyl-L-homocysteine


name: ZFP36 (TTP) recruits RNA degradation activities (Rattus norvegicus)


name: mycophenolyl-CoA + propanoyl-CoA <=> (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + CoA


name: FAM20C phosphorylates FAM20C substrates (Xenopus tropicalis)


name: mRNA3 is translated to protein 3a (Homo sapiens)


name: DPP4(1-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Mus musculus)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Drosophila melanogaster)


name: NT5C2 tetramer phosphorylates RBV (Rattus norvegicus)


name: P2Y2 receptor binds ATP and UTP (Homo sapiens)


name: ACY1:Zn2+ dimer hydrolyses mercapturic acids (Xenopus tropicalis)


name: D-glucose + O2 <=> 2-dehydro-D-glucose + H2O2


name: DHNTP is dephosphorylated by PTPS to PTHP (Rattus norvegicus)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)


name: chloride(out) + 2 hydrogencarbonate(in) <=> chloride(in) + 2 hydrogencarbonate(out)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Canis familiaris)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Sus scrofa)


name: (3R)-hydroxytetracosanoyl-CoA + NAD(+) => 3-oxotetracosanoyl-CoA + H(+) + NADH


name: (3R)-citramalyl-CoA + succinate => (3R)-citramalate + succinyl-CoA


name: glyoxylate(in) + sulfate(out) <=> glyoxylate(out) + sulfate(in)


name: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Danio rerio)


name: complement component C1q receptor activity


name: RHOB binds effectors on endosomes (Canis familiaris)


name: Follitropin is a heterodimer (Gallus gallus)


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Bos taurus)


name: cyclohexane-1-carboxylate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + trans-4-hydroxycyclohexane-1-carboxylate


name: STON2 binds SYT proteins (Gallus gallus)


name: UDP-glucose is oxidised to UDP-glucuronate (Homo sapiens)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Homo sapiens)


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate <=> ectocarpin A + H2O


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Rattus norvegicus)


name: depalmitoylation of eNOS (Rattus norvegicus)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Canis familiaris)


name: diphosphate + fusoxypene A => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: SLC26A4 transports I- from cytosol to extracellular region (Mus musculus)


name: hexadecanoyl-[ACP] + L-lysyl-[protein] => H(+) + holo-[ACP] + N(6)-hexadecanoyl-L-lysyl-[protein]


name: L-cysteine + O-succinyl-L-homoserine => H(+) + L,L-cystathionine + succinate


name: Phosphorylation of TBSMs in LAT (Bos taurus)


name: Glucosylation of collagen propeptide hydroxylysines (Sus scrofa)


name: H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: MUS81 binds EME1, EME2 (Rattus norvegicus)


name: ATP + glycyl-L-glutamate(out) + H2O = ADP + glycyl-L-glutamate(in) + H(+) + phosphate


name: Autophosphorylation of PAK1,2,3 (Homo sapiens)


name: Activation of Protein Kinase C novel isoforms (Danio rerio)


name: Orexin 2 receptor can bind orexin-B neuropeptide (Rattus norvegicus)


name: Rag dimer formation (Schizosaccharomyces pombe)


name: 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + H2O + L-glutamine <=> 5-phosphoribosylamine + L-glutamate +pyrophosphate (Bos taurus)


name: Interaction of PECAM-1 and SHP-1 (Rattus norvegicus)


name: 2-[(L-alanin-3-ylcarbamoyl)methyl]-3-(2-aminoethylcarbamoyl)-2-hydroxypropanoate + 2-oxoglutarate + ATP <=> AMP + diphosphate + H(+) + staphyloferrin B


name: (deoxy)nucleoside phosphate kinase activity, dGTP as phosphate donor


name: a 2'-deoxyribonucleoside 5'-phosphate + dGTP = a 2'-deoxyribonucleoside 5'-diphosphate + dGDP


name: ADORA2A,B bind Ade-Rib (Xenopus tropicalis)


name: (E)-hexadec-2-enoate(out) + ATP(in) + CoA(in) + H(+)(out) => (2E)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: 3,3',5-triiodo-L-thyronine(out) + L-tryptophan(in) <=> 3,3',5-triiodo-L-thyronine(in) + L-tryptophan(out)


name: Association of LBP with LPS (Rattus norvegicus)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Xenopus tropicalis)


name: ADP + alpha-D-ribose 1-phosphate <=> alpha-D-ribose 1,5-bisphosphate + AMP + H(+)


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Mus musculus)


name: 1-(ergostan-3beta-yl)-L-aspartate + tRNA(Asp) => ergosterol + L-aspartyl-tRNA(Asp)


name: N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine => H(+) + N(6)-methyl,N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-homocysteine


name: 3,4-dihydroxybenzoate + UDP-alpha-D-glucose = 1-O-(3,4-dihydroxy-benzoyl)-beta-D-glucose + UDP


name: Phosphorylated PXN recruits the CRK complex (Canis familiaris)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Canis familiaris)


name: (3S,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol = (+)-medicarpin + H2O


name: ATP + H2O + phosphonate(out) <=> ADP + H(+) + phosphate + phosphonate(in)


name: Phosphorylated Cdc6 is exported from the nucleus (Mus musculus)


name: H2O + N(omega)-methyl-L-arginine = L-citrulline + methylamine


name: ferruginol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + salviol


name: 2-dehydro-3-deoxy-D-gluconate + NH4(+) => (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O


name: ECE2 cleaves EDN1(53-90) (Xenopus tropicalis)


name: a 5'-end diphospho-guanosine in mRNA + GTP + H(+) => a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + diphosphate


name: ADPRM hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)


name: Internalization of ubiquitinated FLT3 (Mus musculus)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Sus scrofa)


name: B3GNT5 transfers GlcNAc to LacCer (Danio rerio)


name: AhpC reduces peroxidated lipids (Homo sapiens)


name: IL37(?-218):p-S423,S425-SMAD3 translocates to the nucleus (Danio rerio)


name: a 1-acyl-sn-glycero-3-phosphate + NADP(+) => a 1-acylglycerone 3-phosphate + H(+) + NADPH


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Bos taurus)


name: CRHR1,CRHR2-1 binds CRH,UCN (Homo sapiens)


name: Translocation of coproporphyrinogen III from the cytosol to the mitochondrial intermembrane space (Gallus gallus)


name: aminoacetaldehyde + CO2 + NADPH => L-serine + NADP(+)


name: 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate => H2O + xanthurenate


name: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate <=> oxaloacetate + pyruvate


name: Formation of hydroxylysyl-pyrrole cross-links (Rattus norvegicus)


name: pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (Gallus gallus)


name: a long-chain fatty aldehyde + holo-[ACP] + NAD(+) <=> a long-chain fatty acyl-[ACP] + H(+) + NADH


name: Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)


name: WWTR1 (TAZ) binds TEAD (Xenopus tropicalis)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Gallus gallus)


name: SLC25A18,22 import L-Glu, H+ (Sus scrofa)


name: RAP1A exchanges GDP for GTP (Homo sapiens)


name: FOXP3 in complex with RUNX1 binds intron 1 of the IL2RA (CD25) gene (Homo sapiens)


name: a 5,6-dihydrouridine in tRNA + NADP(+) <=> a uridine in tRNA + H(+) + NADPH


name: D-ribulose 5-phosphate => aldehydo-D-ribose 5-phosphate


name: 3,17-dihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMNH2 + O2 => 3,4,17-trihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMN + H(+) + H2O


name: dibenzothiophene + FMNH2 + O2 <=> dibenzothiophene 5-oxide + FMN + H(+) + H2O


name: Phosphorylated SHC1 recruits SHIP (Mus musculus)


name: p‑Y705-STAT3 dissociates from IL19:IL20RA:p-JAK1:IL20RB (Homo sapiens)


name: P2Y6 receptor can bind to UDP (Rattus norvegicus)


name: H(+) + N-(1H-1,3-benzodiazol-2-yl)carbamate <=> 2-aminobenzimidazole + CO2


name: all-trans-heptaprenyl diphosphate => beta-heptaprene + diphosphate


name: RDH5 oxidises 11cROL to 11cRAL (Danio rerio)


name: an N-acyl-L-phenylalanine + H2O = a fatty acid + L-phenylalanine


name: ATP + L-asparagine + tRNA(Asn) <=> AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)


name: an aliphatic alcohol + H(+) + octadecanoate => H2O + octadecanoate ester


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Caenorhabditis elegans)


name: dimethylallyl diphosphate + umbelliferone => demethylsuberosin + diphosphate


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Rattus norvegicus)


name: NADH + oxidized 2[4Fe-4S]-[ferredoxin] => H(+) + NAD(+) + reduced 2[4Fe-4S]-[ferredoxin]


name: (2E,6E)-farnesyl diphosphate + H2O => 10-epi-juneol + diphosphate


name: 3-hydroxyanthranilate + O2 => (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Homo sapiens)


name: 3,3',5-triiodo-L-thyronine(out) + L-tyrosine(in) <=> 3,3',5-triiodo-L-thyronine(in) + L-tyrosine(out)


name: ERK5 translocates to the nucleus (Gallus gallus)


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Bos taurus)


name: STAT1 and STAT3 dimers translocate to the nucleus (Caenorhabditis elegans)


name: dihydrocarvone + H(+) + NADPH + O2 <=> 4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: ATP + streptidine <=> 6-O-adenylylstreptidine + diphosphate


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Dictyostelium discoideum)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA


name: SCF(beta-TrCP) ubiquitinates p-GLI2 (Homo sapiens)


name: Luteinizing hormone is a heterodimer (Homo sapiens)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Canis familiaris)


name: JAK2 Autophosphorylates in Response to Leptin (Homo sapiens)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Danio rerio)


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Rattus norvegicus)


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Xenopus tropicalis)


name: 2 H(+)(out) + histamine(in) = 2 H(+)(in) + histamine(out)


name: (13Z)-docosenoyl-CoA + H(+) + malonyl-CoA => (15Z)-3-oxotetracosenoyl-CoA + CO2 + CoA


name: Loading of PCNA - Sliding Clamp Formation (Dictyostelium discoideum)


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)


name: PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate => 3-amino-4-hydroxybenzoate + H(+) + 2 H2O + phosphate


name: 2 oxidized [2Fe-2S]-[ferredoxin] + protochlorophyllide a = 3,8-divinyl protochlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH => deoxycholate + NAD(+)


name: 4-hydroxyphenylglyoxylate + L-glutamate => 2-oxoglutarate + D-4-hydroxyphenylglycine


name: ADP + H(+) + sulfate => adenosine 5'-phosphosulfate + phosphate


name: SGMS1 transfers phosphocholine onto ceramide (Plasmodium falciparum)


name: p-T182 MAPKAPK5 binds DNAJB1 (Danio rerio)


name: BCHE hydrolyzes ASA- (Xenopus tropicalis)


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Mus musculus)


name: (5S)-hydroperoxy-(6E,8Z)-octadecadienoate => (5Z,8Z)-octadecadienoate + O2


name: biphenyl-2-ol + H(+) + NADH + O2 = biphenyl-2,3-diol + H2O + NAD(+)


name: 2 H(+) + NADH + sirohydrochlorin => NAD(+) + precorrin-2


name: Formation of the PCAF-ATAC complex (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol = 1-octadecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: p-CD19:VAV binds PI3K and GRB2 (Rattus norvegicus)


name: H(+) + lipid A disaccharide (E. coli) + UDP => 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine


name: germacra-1(10),4,11(13)-trien-12-ol + O2 + reduced [NADPH--hemoprotein reductase] => germacra-1(10),4,11(13)-trien-12-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it (Mus musculus)


name: CBL monoubiquitinates activated MET (Homo sapiens)


name: CYP17A1 cleaves 17aHPREG to DHA (Xenopus tropicalis)


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Xenopus tropicalis)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-tetradecanoyl-sn-glycerol + H(+) + phosphocholine


name: D-glucose(out) + H(+)(out) <=> D-glucose(in) + H(+)(in)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Drosophila melanogaster)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Drosophila melanogaster)


name: (2S)-2-amino-2'-deoxyadenylo-succinate + ADP + 2 H(+) + phosphate => ATP + dGMP + L-aspartate


name: H(+)(in) + L-citrulline(in) + L-ornithine(out) <=> H(+)(out) + L-citrulline(out) + L-ornithine(in)


name: glyoxylate + L-glutamate => 2-oxoglutarate + glycine


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Sus scrofa)


name: ERCC8 (CSA) binds stalled RNA Pol II (Bos taurus)


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Rattus norvegicus)


name: CDK and DDK associate with the Mcm10:pre-replicative complex (Sus scrofa)


name: TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Sus scrofa)


name: Isomerization of GlcNAc6P to GlcNAc1P (Bos taurus)


name: SUMOylation of NCOA1 with SUMO1 (Mus musculus)


name: (2E)-nonenoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + nonanoyl-CoA + oxidized [electron-transfer flavoprotein]


name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Homo sapiens)


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Canis familiaris)


name: Interleukin-2 receptor alpha binds interleukin-2 (Mus musculus)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Sus scrofa)


name: Caspase mediated cleavage of BAP31 (Canis familiaris)


name: gibberellin A3 + S-adenosyl-L-methionine => O-methyl gibberellin A3 + S-adenosyl-L-homocysteine


name: 9-decenoate + ATP + CoA => 9-decenoyl-CoA + AMP + diphosphate


name: a menaquinone + formate + H(+) => a menaquinol + CO2


name: (2S,5S)-5-carboxymethylproline + ATP => (3S,5S)-carbapenam-3-caboxylate + AMP + diphosphate + H(+)


name: (S)-2-methyl-3-oxopropanoate + L-alanine = (S)-3-amino-2-methylpropanoate + pyruvate


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Xenopus tropicalis)


name: glycine + H2O + kynurenate => glyoxylate + L-kynurenine


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Rattus norvegicus)


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Rattus norvegicus)


name: ADP + carbamoyl phosphate + H(+) + H2O => ATP + hydrogencarbonate + NH4(+)


name: H2O + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] => ADP-D-ribose + L-lysyl-[protein]


name: 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine


name: (3R)-hydroxy-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+) => 3-oxo-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + NADPH


name: [HPr protein]-L-serine + ATP <=> [HPr protein]-O-phospho-L-serine + ADP + H(+)


name: Association of gamma-H2AX with MCPH1 (Gallus gallus)


name: Dimerization of Tie2/Ang1 complex (Mus musculus)


name: DENND3 exchanges GTP for GDP on RAB12 (Rattus norvegicus)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Mus musculus)


name: (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2 => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2


name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)


name: Association of procollagen type XIX (Caenorhabditis elegans)


name: H2O + N-acetyltyramine = acetate + tyramine


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Danio rerio)


name: 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + ATP + CoA = 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Homo sapiens)


name: 7-methylxanthosine + H2O => 7-methylxanthine + D-ribose + H(+)


name: NAGLU hydrolyses heparan chain(2) (Dictyostelium discoideum)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Xenopus tropicalis)


name: ATP + D-tyrosine + tRNA(Tyr) => AMP + D-tyrosyl-tRNA(Tyr) + diphosphate + H(+)


name: Activated FGFR2 phosphorylates PPTN11 (Gallus gallus)


name: CDC6 gene expression is stimulated by E2F1 and repressed by the DREAM complex (Homo sapiens)


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: PGE2 is converted to PGF2a by CBR1 (Homo sapiens)


name: NPHP4 protein binds LATS proteins (Gallus gallus)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Xenopus tropicalis)


name: ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Xenopus tropicalis)


name: TTYH1 transports cytosolic Cl- to extracellular region (Xenopus tropicalis)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Homo sapiens)


name: CoA + pyrethrin I => (1R,3R)-chrysanthemoyl-CoA + (Z,S)-pyrethrolone


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Sus scrofa)


name: PKC-delta translocates to plasma membrane (Drosophila melanogaster)


name: MTA is cleaved and phosphorylated (Bos taurus)


name: D-serine(in) + H(+)(in) => D-serine(out) + H(+)(out)


name: H(+) + kaempferol 3-O-beta-D-xyloside + UDP => kaempferol + UDP-alpha-D-xylose


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Homo sapiens)


name: GBF1 stimulates nucleotide exchange on ARF4 (Rattus norvegicus)


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)


name: HRSP12 deaminates 2AA to 2OBUTA (Dictyostelium discoideum)


name: glycyl-sarcosine(out) + H(+)(out) => glycyl-sarcosine(in) + H(+)(in)


name: 2 A + urobilinogen => (4Z,15Z)-mesobilirubin IXalpha + 2 AH2


name: Phosphorylation and activation of VAV (Sus scrofa)


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Gallus gallus)


name: MRRF binds 55S ribosome:mRNA:tRNA (Homo sapiens)


name: SLC4A4 cotransports Na+ with 3HCO3- (Rattus norvegicus)


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Mus musculus)


name: Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA (Homo sapiens)


name: H2O + O2 + vanillin = H(+) + H2O2 + vanillate


name: Fe(II)-hydroxyheme i = Fe(II)-heme a + H2O


name: Phosphorylation of MEF2 proteins by p38 (Caenorhabditis elegans)


name: a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GA1 (d18:1(4E)) + H(+) + UDP


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Bos taurus)


name: D-mannonate + NAD(+) <=> H(+) + keto-D-tagaturonate + NADH


name: p75NTR and RHOA-GDI interact (Danio rerio)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Schizosaccharomyces pombe)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Mus musculus)


name: CDK1 phosphorylates LPIN (Canis familiaris)


name: AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA => adenosine(37) in tRNA + L-threonylcarbamoyladenylate


name: steviolbioside + UDP-alpha-D-glucose = H(+) + rebaudioside B + UDP


name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria (Canis familiaris)


name: 2-dehydro-3-deoxy-L-arabinonate <=> 2,5-dioxopentanoate + H2O


name: L-tetrahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => 2 H(+) + H2O + N-hydroxy-L-tetrahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + 4-amino-L-phenylalanine <=> 3-(4-aminophenyl)pyruvate + L-glutamate


name: alpha-secretase cleaves the p75NTR extracellular domain (Mus musculus)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Sus scrofa)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Rattus norvegicus)


name: CYP1A2, 3A4 oxidise AFB1 to AFNBO (Sus scrofa)


name: MBTPS1 (S1P) cleaves CREB3L3 (Bos taurus)


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Gallus gallus)


name: ARF1:GTP binds Golgin TRIP11 (Homo sapiens)


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Rattus norvegicus)


name: CYP7B1 7-hydroxylates 25OH-CHOL (Bos taurus)


name: CTP(out) + dUMP(in) = CTP(in) + dUMP(out)


name: a 1-O-alkyl-2-acetyl-sn-glycerol + H2O <=> 1-O-alkyl-sn-glycerol + acetate + H(+)


name: 9-hexadecanoyloxy-octadecanoate + H2O => 9-hydroxy-octadecanoate + H(+) + hexadecanoate


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Mus musculus)


name: chloride(out) + creatine(out) + 2 Na(+)(out) <=> chloride(in) + creatine(in) + 2 Na(+)(in)


name: prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer (Sus scrofa)


name: Factor Xa inhibitors bind Va:Xa (Gallus gallus)


name: 4-aminobutanoate(in) + H(+)(in) = 4-aminobutanoate(out) + H(+)(out)


name: Binding of TFIIIA To type 1 Promoter (Dictyostelium discoideum)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Rattus norvegicus)


name: acetyl-CoA + L-seryl-[protein] <=> CoA + O-acetyl-L-seryl-[protein]


name: H2O + octanoylglycerol => glycerol + H(+) + octanoate


name: H2O + N-octadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => (9Z)-octadecenoate + H(+) + N-octadecanoyl-sn-glycero-3-phospho-ethanolamine


name: 6-carboxyhexanoyl-CoA + NAD(+) <=> 6-carboxyhex-2-enoyl-CoA + H(+) + NADH


name: 17-(4-hydroxyphenyl)heptadecanoate + ATP + H(+) = 17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine => a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline


name: ERBB2 KD mutants bind trastuzumab (Homo sapiens)


name: alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose => beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 H(+) + 2 UDP


name: Activated PCLG1 dissociates from NTRK2 (Bos taurus)


name: PPE2:KPNA1:KPNB1 dissociates, releasing PPE2 into the nucleus (Homo sapiens)


name: (3R)-hydroxybutanoate pentamer + H2O => (3R)-hydroxybutanoate tetramer + (R)-3-hydroxybutanoate + H(+)


name: H2O + TTP = 5-methyl-UMP + diphosphate + H(+)


name: Defective ALG8 does not add glucose to the N-glycan precursor (Homo sapiens)


name: CYP3A4 oxidizes PREDN,PREDL (Gallus gallus)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Canis familiaris)


name: 3-amino-2-hydroxy-4-methoxybenzoate + H(+) + S-adenosyl-L-homocysteine => 3-amino-2,4-dihydroxybenzoate + S-adenosyl-L-methionine


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose = [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n+1)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Canis familiaris)


name: (E)-feruloyl-CoA + ADP + phosphate => (E)-ferulate + ATP + CoA


name: ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine


name: a 1-acyl-sn-glycero-3-phospholipid + a fatty acid + H(+) => a glycerophospholipid + H2O


name: acetyl-CoA + N-hydroxyputrescine <=> CoA + N(1)-acetyl-N(1)-hydroxyputrescine


name: SIRP beta binds TYROBP (Canis familiaris)


name: H2O + streptothricin F = streptothricin F acid


name: Formation of the MCC complex (Sus scrofa)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Xenopus tropicalis)


name: (3R)-hydroxydocosanoyl-CoA + NAD(+) => 3-oxodocosanoyl-CoA + H(+) + NADH


name: 1,4-benzoquinone + H(+) + NADH <=> hydroquinone + NAD(+)


name: Further sulfation on galactose residues produces KSPG (Sus scrofa)


name: Caspase-mediated cleavage of Rock-1 (Homo sapiens)


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Caenorhabditis elegans)


name: MeSec is hydrolysed to MeSeH by PXLP-K212-CTH (Homo sapiens)


name: a 2'-deoxyuridine in double-stranded DNA + NH4(+) => a 2'-deoxycytidine in double-stranded DNA + H(+) + H2O


name: SUMOylation of NOP58 with SUMO1 (Rattus norvegicus)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) (Mus musculus)


name: Formation of Pol zeta complex (Plasmodium falciparum)


name: 5-cis-lycopene + O2 = (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one + 5-cis-10'-apo-lycopenal


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + ethanolamine


name: a C27-steroid + O2 + reduced [NADPH--hemoprotein reductase] => a (22S)-22-hydroxy C27-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TXLNA (IL14) binds syntaxin3 (Drosophila melanogaster)


name: (2S)-5,5-dimethylpiperidine-2-carboxylate + 10-hydroxy-pre-flavunoidine + ATP => AMP + diphosphate + flavunoidine + H(+)


name: 3',5'-cyclic GMP(in) = 3',5'-cyclic GMP(out)


name: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O <=> 1D-myo-inositol 1,4,5-trisphosphate + phosphate


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Canis familiaris)


name: eNOS associates with Caveolin-1 (Homo sapiens)


name: Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Mus musculus)


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Sus scrofa)


name: trans-Golgi Network Coat Activation (Canis familiaris)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Canis familiaris)


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Drosophila melanogaster)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Caenorhabditis elegans)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH => isodeoxycholate + NADP(+)


name: IGF1,2:IGF1R autophosphorylates (Homo sapiens)


name: (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH => H2O + L-saccharopine + NADP(+)


name: 4 monapinone A + O2 <=> 2 dinapinone A + 2 H2O


name: hydroxyacetone + NADP(+) <=> H(+) + methylglyoxal + NADPH


name: PDGF-AA clevage by Furin (Drosophila melanogaster)


name: USP12, USP26 deubiquitinate AR (Drosophila melanogaster)


name: H2O + S-(ADP-D-ribosyl)-L-cysteinyl-[protein] = ADP-D-ribose + L-cysteinyl-[protein]


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-3-octadecanoyl-sn-glycerol + H(+)


name: Transport of MHC II:Ii complex to plasma membrane (Mus musculus)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O


name: putrescine + S-adenosyl-L-methionine = H(+) + N-methylputrescine + S-adenosyl-L-homocysteine


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Bos taurus)


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Canis familiaris)


name: ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Gallus gallus)


name: Autophosphorylation of PDGF beta receptors (Caenorhabditis elegans)


name: NADP(+) + taurochenodeoxycholate = 7-oxotaurolithocholate + H(+) + NADPH


name: CXXC1 and WDR82 bind SET1A complex (Rattus norvegicus)


name: Oligomerization of CARMA1 (Gallus gallus)


name: (1'S,5'S)-5'-hydroxyaverantin + NAD(+) = (S)-5'-oxoaverantin + H(+) + NADH


name: HEXB cleaves the terminal GalNAc from small HA fragments (Homo sapiens)


name: Expression of PDIA6 (Protein disulfide-isomerase A6) (Homo sapiens)


name: (+)-abscisic acid D-glucopyranosyl ester + H2O = 2-cis-(+)-abscisate + beta-D-glucose + H(+)


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Homo sapiens)


name: Src phosphorylate WASP,N-WASP (Homo sapiens)


name: H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine


name: FANCM:FAAP24 and APITD1:STRA13 bind ICL-DNA (Homo sapiens)


name: (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase] => 16-hydroxytabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dissociation of CaM and CAMK2 autophosphorylation (Caenorhabditis elegans)


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Bos taurus)


name: Factor H binds to membrane-associated C3b (Canis familiaris)


name: E-cadherin degradation by ADAM10, ADAM15 (Drosophila melanogaster)


name: a globoside GalGb4Cer (d18:1(4E)) + GDP-beta-L-fucose = a globoside Globo-H (d18:1(4E)) + GDP + H(+)


name: CYP26C1 4-hydroxylates 9cRA (Sus scrofa)


name: acetyl-CoA + N-terminal L-methionyl-L-aspartyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein]


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine <=> diphthine methyl ester-[translation elongation factor 2] + 3 H(+) + 4 S-adenosyl-L-homocysteine


name: 7-deoxyloganetic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-cis-trans-nepetalactol + O2 + reduced [NADPH--hemoprotein reductase]


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Canis familiaris)


name: Phosphorylated heterodimers of ERBB2 KD mutants bind SHC1 (Homo sapiens)


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate => 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-glucose


name: factor XIIa binds SERPING1 (Homo sapiens)


name: IKBKG subunit of IKK complex binds polyubiquinated RIP1 (Rattus norvegicus)


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Homo sapiens)


name: Collagen type XIII ectodomain shedding (Sus scrofa)


name: H2O + N-hexacosanoyl-(4R)-hydroxysphinganine = (4R)-hydroxysphinganine + hexacosanoate


name: MASTL (GWL) phosphorylates ARPP19 (Homo sapiens)


name: L-homocysteine => 2-aminobut-2-enoate + H(+) + hydrogen sulfide


name: ADP + H(+) + N-(3-O-phospho-D-erythrulosyl)-cadaverine => ATP + N-(D-erythrulosyl)-cadaverine


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Rattus norvegicus)


name: H(+)(out) + K(+)(in) + L-glutamate(out) + 3 Na(+)(out) <=> H(+)(in) + K(+)(out) + L-glutamate(in) + 3 Na(+)(in)


name: (E)-isoeugenol + S-adenosyl-L-methionine => (E)-isomethyleugenol + H(+) + S-adenosyl-L-homocysteine


name: UBXN1 binds BRCA1:BARD1 heterodimer (Rattus norvegicus)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Mus musculus)


name: 5-oxo-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase] <=> 5-oxo-18-hydroxy-(6E,8Z)-octadecadienoate + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: acetyl-CoA + N-terminal L-leucyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-leucyl-[protein]


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Dictyostelium discoideum)


name: MSL acetylates histone H4 (Rattus norvegicus)


name: 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-heptadecanoyl-sn-glycero-3-phosphoserine + H(+)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Danio rerio)


name: EGFR activates PLC-gamma1 by phosphorylation (Bos taurus)


name: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + H(+) + NADPH + O2 => [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + H2O + NADP(+)


name: HBEGF-bound EGFR forms a heterodimer with GPNMB (Xenopus tropicalis)


name: 3,5,7,9,11-pentaoxododecanoyl-[ACP] + 5 CO2 + 6 CoA => acetyl-CoA + 5 H(+) + holo-[ACP] + 5 malonyl-CoA


name: Retromer associates with WLS (Canis familiaris)


name: FAD-dependent histone H3K9me/H3K9me2 demethylase activity


name: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + UDP-alpha-D-glucuronate <=> an alpha-D-glucuronosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + H(+) + UDP


name: Expression of TFAP2C in primordial germ cells (Homo sapiens)


name: phenylethanolamine + S-adenosyl-L-methionine <=> H(+) + N-methylphenylethanolamine + S-adenosyl-L-homocysteine


name: SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Gallus gallus)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Dictyostelium discoideum)


name: a 1-[(9Z,12Z,15Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate (Gallus gallus)


name: D-xylono-1,4-lactone 5-phosphate + H2O => 5-phospho-D-xylonate + H(+)


name: 3-hydroxyanthranilate + S-adenosyl-L-methionine => 3-hydroxy-4-methylanthranilate + H(+) + S-adenosyl-L-homocysteine


name: IRAK1 binds to MYD88 within the IL1R complex (Rattus norvegicus)


name: TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Rattus norvegicus)


name: NTP Binds Active Site of RNA Polymerase II (Homo sapiens)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Gallus gallus)


name: RET tyrosine phosphorylation (Gallus gallus)


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: pseudouridine(13) in tRNA => uridine(13) in tRNA


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Homo sapiens)


name: USP30 deubiquitinates Ub-MOM proteins (Canis familiaris)


name: 5-hydroxythiophene-2-carbonyl-CoA + H2O = 4-carboxy-2-thioxobutanoyl-CoA


name: a dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] <=> 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a dolichyl phosphate + H(+)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Mus musculus)


name: 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H(+) => 3',3'-c-di-AMP + H2O


name: 2 (S)-methylmalonyl-CoA + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH <=> C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)


name: Nascent CMs transform into mature CMs (Mus musculus)


name: PTGS1 dimer binds PTGS1 Inhibitors (Homo sapiens)


name: an N-acylsphinganine + UDP-alpha-D-glucose => an N-acyl-beta-D-glucosyl-(1<->1')-sphinganine + H(+) + UDP


name: CUBN dissociates from 25(OH)D (Drosophila melanogaster)


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Caenorhabditis elegans)


name: daidzein + UDP-alpha-D-glucose => daidzein 7-O-beta-D-glucoside + UDP


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA2 (d18:1(4E)/18:0) <=> CMP + ganglioside GM2 (d18:1(4E)/18:0) + H(+)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Drosophila melanogaster)


name: Collagen type II degradation by MMP15 (Sus scrofa)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Gallus gallus)


name: H(+) + H2O + N-terminal L-asparaginyl-[protein] = N-terminal L-aspartyl-[protein] + NH4(+)


name: "protein N-terminal asparagine amidohydrolase"


name: 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2 = CO2 + H2O + NAD(+) + naphthalene-1,2-diol


name: 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Sus scrofa)


name: D-cycloserine(in) + H(+)(in) => D-cycloserine(out) + H(+)(out)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + testosterone => 17beta-estradiol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Mus musculus)


name: LARP1 binds SARS-CoV-2 RNA (Homo sapiens)


name: H(+) + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine => adenosine(58) in tRNA + S-adenosyl-L-methionine


name: H(+) + rhamnacene + S-adenosyl-L-homocysteine => isorhamnetin + S-adenosyl-L-methionine


name: (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol <=> 1-octadecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: L-erythro-7,8-dihydrobiopterin + NADP(+) => H(+) + NADPH + sepiapterin


name: CARNMT1 methylates CARN to Anserine (Bos taurus)


name: Prolysyl oxidase activation (Homo sapiens)


name: HRSP12 deaminates 2AA to 2OBUTA (Homo sapiens)


name: deoxynogalonate + O2 => H(+) + H2O + nogalonate


name: 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide + NAD(+) = H(+) + momilactone A + NADH


name: RAC1 binds effectors at the plasma membrane (Drosophila melanogaster)


name: MDM2 translocates to the cytosol (Rattus norvegicus)


name: (2E,4E)-hexadienoyl-CoA + H(+) + NADPH <=> (3E)-hexenoyl-CoA + NADP(+)


name: Pink1 is cleaved on healthy mitochondria (Canis familiaris)


name: 24S,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: (11Z,14Z,17Z)-eicosatrienamide + H2O <=> (11Z,14Z,17Z)-eicosatrienoate + NH4(+)


name: [Glu(-Cys)](n+1)-Gly + glycine => [Glu(-Cys)](n)-Gly + glutathione + H(+)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Caenorhabditis elegans)


name: Activated MET recruits GRB2-1:SOS1 (Gallus gallus)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O <=> beta-methylcrotonyl-CoA + ATP + CO2 [MCCA] (Canis familiaris)


name: 4beta-methylzymosterol-4alpha-carbaldehyde + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4beta-methylzymosterol-4alpha-carboxylate + 2 Fe(III)-[cytochrome b5] + H2O


name: eburicol + O2 + reduced [NADPH--hemoprotein reductase] => 32-hydroxyeburicol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an S-substituted L-cysteine + H2O <=> a thiol + NH4(+) + pyruvate


name: Formation of tonofilament bundles (Sus scrofa)


name: TXNIP binds reduced thioredoxin (Bos taurus)


name: H(+) + NADPH + O2 + versicolorin B => 2 H2O + NADP(+) + versicolorin A


name: p-STAT5 dissociates from the receptor complex (Homo sapiens)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Schizosaccharomyces pombe)


name: Formation of lysyl-pyridinoline cross-links (Rattus norvegicus)


name: a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acid + H(+) => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: NEIL3 recognizes and binds to spiroiminodihydantoin (Homo sapiens)


name: protein serine/threonine kinase inhibitor activity


name: PHLPP dephosphorylates S473 in AKT (Homo sapiens)


name: H(+) + H2O + hydrazine => hydroxylamine + NH4(+)


name: Internalization of gap junction plaques (Bos taurus)


name: acetaldehyde + CO2 => 3-oxopropanoate + H(+)


name: histone H3K56 acetyltransferase activity


name: Urotensin-2 receptor binds urotensin-2 and 2B (Xenopus tropicalis)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Plasmodium falciparum)


name: DHODH:FMN binds DHODH inhibitors (Schizosaccharomyces pombe)


name: Transamination of MOB to methionine (Homo sapiens)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Canis familiaris)


name: Hydroperoxy reductase reduces 7,17-diHp-DPAn-3 to RvD5n-3DPA (Homo sapiens)


name: Formation of MSH2:MSH3 Complex (Bos taurus)


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Rattus norvegicus)


name: dimethylallyl diphosphate + 2 isopentenyl diphosphate = (2Z,6Z)-farnesyl diphosphate + 2 diphosphate


name: H2O + uridine 2'-phosphate <=> phosphate + uridine


name: (2S)-2-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: prostaglandin E2 => H2O + prostaglandin A2


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Gallus gallus)


name: 5-dehydroepisterol + H(+) + NADPH + O2 => ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2 H2O + NADP(+)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Homo sapiens)


name: 2'-deoxyuridine + 2-oxoglutarate + O2 => CO2 + succinate + uridine


name: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO2


name: PIAS4 SUMOylates HERC2 with SUMO1 (Bos taurus)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Canis familiaris)


name: Ca2+ influx through voltage gated Ca2+ channels (Drosophila melanogaster)


name: H2O2 + NH4(+) + succinate semialdehyde => 4-aminobutanoate + H2O + O2


name: (3R)-3,8,9,10-tetrahydroxy-6-methyl-1,2,3,4-tetrahydroanthracen-1-one + NADP(+) => 3,8,9,10-tetrahydroxy-6-methyl-1,4-dihydroanthracen-1-one + H(+) + NADPH


name: NPC transports GCK1:GKRP from cytosol to nucleoplasm (Homo sapiens)


name: Recruitment of IKK complex (Gallus gallus)


name: Activation of Rap1 by cytosolic GEFs (Xenopus tropicalis)


name: Association of Emi1 with Cdc20 (Mus musculus)


name: alpha-isomaltosyl-(1->3)-isomaltose => cyclobis-(1->3)-alpha-D-isomaltosyl + H2O


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Bos taurus)


name: Phosphorylation of Syntaxin-4 (Sus scrofa)


name: N-acetyl-alpha-neuraminate(out) + 2 Na(+)(out) = N-acetyl-alpha-neuraminate(in) + 2 Na(+)(in)


name: RAC3 translocates to the endoplasmic reticulum membrane (Caenorhabditis elegans)


name: (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol (Mus musculus)


name: BTNL8 binds resting T cell surface (Xenopus tropicalis)


name: 2 glyoxylate + H(+) <=> 2-hydroxy-3-oxopropanoate + CO2


name: L-threonine(in) + Na(+)(in) => L-threonine(out) + Na(+)(out)


name: DHCR24 reduces ZYMOL to ZYMSTNL (Xenopus tropicalis)


name: sodium-transporting ATPase activity, rotational mechanism


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Drosophila melanogaster)


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)


name: SUMOylation of NOP58 with SUMO1 (Danio rerio)


name: choloyl-CoA + taurine = CoA + H(+) + taurocholate


name: (20S)-ginsenoside Rb1 + H2O = (20S)-ginsenoside Rd + D-glucose


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Xenopus tropicalis)


name: (2E)-geranyl diphosphate + isopentenyl diphosphate <=> (2E,6E)-farnesyl diphosphate + diphosphate


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: 2 Fe(III)-[cytochrome c] + L-gulono-1,4-lactone => 2 Fe(II)-[cytochrome c] + 3 H(+) + L-ascorbate


name: 2 Na(+)(out) + propanoate(out) = 2 Na(+)(in) + propanoate(in)


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Homo sapiens)


name: I(1,3,4,5,6)P5 transports from the nucleus to the cytosol (Homo sapiens)


name: Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Bos taurus)


name: PIAS1 SUMOylates L3MBTL2 with SUMO2 (Gallus gallus)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Danio rerio)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: (9Z)-hexadecenoyl-CoA + FAD + H(+) => (2E,9Z)-hexadecadienoyl-CoA + FADH2


name: NEIL3 cleaves 5-guanidinohydantoin (Homo sapiens)


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl beta-D-glucuronate(in) + ATP + H2O = 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl beta-D-glucuronate(out) + ADP + H(+) + phosphate


name: H2O + quercetin 4'-O-beta-D-glucoside = beta-D-glucose + quercetin


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + gamma-humulene


name: misfolded CFTR is degraded by the 26S proteasome (Bos taurus)


name: sCD163 binds MYH9 in T-cells (Homo sapiens)


name: STARD10 binds LPCAT1 and PC (Bos taurus)


name: (24S)-hydroxycholesterol 3,24-disulfate + adenosine 3',5'-bisphosphate + H(+) => (24S)-hydroxycholesterol 24-sulfate + 3'-phosphoadenylyl sulfate


name: D-glucuronate + N(2),6-disulfo-D-glucosamine => 3-D-glucuronosyl-N(2),6-disulfo-beta-D-glucosamine + H2O


name: Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA (Bos taurus)


name: GDPD3 hydrolyzes LysoPtdCho (Homo sapiens)


name: 2 H(+) + H2O + N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase] => L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase]


name: GGPS1 hexamer transfers IPPP to DMAPP (Dictyostelium discoideum)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Sus scrofa)


name: Class III antiarrhythmics bind KCNH2 in KCNH2:KCNE (Mus musculus)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Sus scrofa)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Caenorhabditis elegans)


name: SUMOylation of NFKB2 with SUMO1 (Bos taurus)


name: IL37(?-218):p-S423,S425-SMAD3 translocates to the nucleus (Homo sapiens)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Sus scrofa)


name: SLC38A9 binds Ragulator:Rag dimers (Homo sapiens)


name: acetaldehyde + H(+) + phosphate => H2O + phosphonoacetaldehyde


name: (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine => D-histidine + S-adenosyl-L-methionine


name: Active G alpha (q) binds RGS proteins (Schizosaccharomyces pombe)


name: FAM20C phosphorylates FAM20C substrates (Drosophila melanogaster)


name: Activated type I receptor phosphorylates SMAD2/3 directly (Sus scrofa)


name: choline(in) + 2 H(+)(out) <=> choline(out) + 2 H(+)(in)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Dictyostelium discoideum)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Sus scrofa)


name: 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H2O


name: HMG CoA => acetoacetic acid + acetyl CoA (Caenorhabditis elegans)


name: GDP-alpha-D-glucose + H2O = D-glucose + GDP + H(+)


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Mus musculus)


name: 2-cis,4-trans-xanthoxin + NAD(+) <=> 2-cis-(+)-abscisic aldehyde + H(+) + NADH


name: scyllo-inosose => 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O


name: RHOC activates endoplasmic reticulum effectors (Bos taurus)


name: RUNX2 binds STUB1 (Drosophila melanogaster)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains (Rattus norvegicus)


name: CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein] => (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein]


name: NPC2 transfers CHOL to NPC1 (Saccharomyces cerevisiae)


name: a (1E)-1-aci-nitro-omega-(methylsulfanyl)alkane + glutathione => an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H2O


name: Collagen type VIII degradation by MMP1 (Sus scrofa)


name: ornithine decarboxylase regulator activity


name: dihydrosterigmatocystin + S-adenosyl-L-methionine = 8-O-methyldihydrosterigmatocystin + H(+) + S-adenosyl-L-homocysteine


name: SPTLC complexes transfer acyl-CoA onto serine (Homo sapiens)


name: NF-kappaB translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: H2O + N-(long-chain-fatty-acyl)-L-glutamate <=> a long-chain fatty acid + L-glutamate


name: L-glutamate + prephenate => 2-oxoglutarate + L-arogenate


name: 3,7,11,15-tetramethylhexadecanoate + CoA + H(+) => H2O + phytanoyl-CoA


name: H(+) + N-ethylmaleimide + NADPH <=> N-ethylsuccinimide + NADP(+)


name: dihydromonacolin L carboxylate + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + 2 H2O + monacolin L carboxylate + oxidized [NADPH--hemoprotein reductase]


name: 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Saccharomyces cerevisiae)


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Sus scrofa)


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Mus musculus)


name: HLCS biotinylates 6xMCCC1:6xMCCC2 (Dictyostelium discoideum)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Saccharomyces cerevisiae)


name: L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine => H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine


name: IL1R1:IL1:IL1RAP binds MYD88 homodimer (Canis familiaris)


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Bos taurus)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Bos taurus)


name: 1D-myo-inositol 4-phosphate + H2O => myo-inositol + phosphate


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Dictyostelium discoideum)


name: TP53 stimulates expression of the TP53I3 (PIG3) gene (Homo sapiens)


name: 2 2-oxoglutarate + gibberellin A12 + H(+) + 3 O2 => 3 CO2 + gibberellin A9 + 2 H2O + 2 succinate


name: 2 D-glyceraldehyde 3-phosphate <=> 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + 2 H2O + phosphate


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Homo sapiens)


name: Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)


name: RHOA GAPs stimulate RHOA GTPase activity (Caenorhabditis elegans)


name: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = oxaloacetate + pyruvate


name: FDPS dimer transfers IPPP to GPP (Sus scrofa)


name: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Canis familiaris)


name: Gamma-carboxy pro-prothrombin transport from the endoplasmic reticulum to the Golgi apparatus (Mus musculus)


name: type 1 proteinase activated receptor binding


name: EET(1) is hydrolysed to DHET(1) by EPHX2 (Mus musculus)


name: PPM1L dephosphorylates multiphospho-CERT1-2 (Drosophila melanogaster)


name: alpha-D-ribose 1,5-bisphosphate + H(+) => alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O


name: H(+) + N(6)-(dimethylallyl)adenosine 5'-phosphate + NADPH + O2 = 9-ribosyl-trans-zeatin 5'-phosphate + H2O + NADP(+)


name: L-phenylalanocholate + taurine => L-phenylalanine + taurocholate


name: GRB2-1:SOS1 binds p-Y427-SHC1 (Mus musculus)


name: (11Z)-eicosenoate + sphing-4-enine => H2O + N-(11Z-eicosenoyl)-sphing-4-enine


name: Cu(2+)(out) + L-ascorbate(in) = Cu(+)(out) + H(+) + monodehydro-L-ascorbate radical(in)


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Sus scrofa)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate <=> goitrin + sulfate


name: ARSB hydrolyses C4S/C6S chains (Sus scrofa)


name: 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: C3G stimulates nucleotide exchange on Rap1 (Canis familiaris)


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) <=> 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)


name: a (2E)-enoyl-CoA + H2O => a 3-hydroxy-fatty acyl-CoA


name: 2xPPCS ligates PPanK with Cys (Homo sapiens)


name: H2O + NADP(+) = ADP-D-ribose 2'-phosphate + H(+) + nicotinamide


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine => an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH => dTDP-alpha-D-fucose + NADP(+)


name: NUDT12 hydrolyses NADH to NMNH (Saccharomyces cerevisiae)


name: Synthesis of minus strand strong stop DNA (-sssDNA) (Homo sapiens)


name: H2O + 2 O2 + sym-homospermidine => 1-formylpyrrolizidine + 2 H2O2 + 2 NH4(+)


name: Retinoic acid activates HOXB1 chromatin (Homo sapiens)


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Canis familiaris)


name: Dissociation of L13a from the 60s ribosomal subunit (Saccharomyces cerevisiae)


name: (2S,3R)-dihydroxy-5-oxohexanedioate + H2O => galactarate


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Canis familiaris)


name: n H(+) + (n+1) phosphate => [phosphate](n+1) + n H2O


name: H(+) + macrocin + S-adenosyl-L-homocysteine => demethylmacrocin + S-adenosyl-L-methionine


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Homo sapiens)


name: [phosphate](n) + UTP <=> [phosphate](n+1) + UDP


name: a carboxylate + AMP + 2 H(+) => 5'-acylphosphoadenosine + H2O


name: n 3'-phosphoadenylyl sulfate + dermatan 4'-sulfate => n adenosine 3',5'-bisphosphate + dermatan 4',6'-bissulfate + n H(+)


name: H(+) + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine => (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine


name: Some HSPGs are secreted to the plasma membrane (Mus musculus)


name: GST dimers conjugate GSH with cytosolic substrates (Canis familiaris)


name: H2O + N(1)-acetylspermine + O2 <=> H2O2 + N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine


name: 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + CO2 + methanol => chlorophyllide a + H(+) + H2O


name: D-cellotriono-1,5-lactone + H2O2 => D-cellotriose + O2


name: a very-long-chain (2E)-enoyl-CoA + H2O => a very-long-chain (3S)-hydroxyacyl-CoA


name: Activated FGFR3 binds PLCG1 (Rattus norvegicus)


name: Expression of TBX5 in cardiogenesis (Homo sapiens)


name: D-maltose + O2 = D-maltobiono-1,5-lactone + H2O2


name: AUF1 (hnRNP D0) is ubiquitinylated (Mus musculus)


name: TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Sus scrofa)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Homo sapiens)


name: N-(8'-hydroxygeranyl)-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + 2 H2O + N-(8'-oxogeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase]


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Canis familiaris)


name: Translocation of Cdc25 to the nucleus (Rattus norvegicus)


name: phosphate + thymidine => H2O + thymidine 3'-phosphate


name: NLRP4 and DTX4 associate with p-S172-TBK1 within dsDNA:ZBP1:TBK1 (Homo sapiens)


name: 2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O


name: ATP + cytidine(34) in tRNA(Ile2) + L-lysine <=> AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)


name: SUMOylation of PML with SUMO3 (Rattus norvegicus)


name: ERBB4 binds NRGs or EGF-like ligands (Sus scrofa)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Rattus norvegicus)


name: HSD17B11 dehydrogenates EST17b to E1 (Sus scrofa)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Sus scrofa)


name: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + AMP + diphosphate => [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + ATP + CoA


name: diphosphate + IC-asc-C7-AMP => ATP + H(+) + IC-asc-C7


name: L-kynurenine(out) + L-tryptophan(in) = L-kynurenine(in) + L-tryptophan(out)


name: Phosphorylation of Cyclin B1 in the CRS domain (Sus scrofa)


name: PS is hydrolyzed to 1-acyl LPS by PLA2[15] (Rattus norvegicus)


name: POM121 binds the Nup107-Nup160 complex (Canis familiaris)


name: 2 AMP + 2 diphosphate + 2 H(+) + putrebactin => 2 ATP + 2 N-(3-carboxypropanoyl)-N-hydroxyputrescine


name: H2O + O-phospho-D-serine = D-serine + phosphate


name: 1,6-dihydroxyphenazine + NADPH + O2 => 1,6-dihydroxyphenazine N(5)-oxide + H2O + NADP(+)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + O2 <=> (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate


name: SST gene expression is stimulated by MECP2 and CREB1 (Homo sapiens)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O => 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: 1,2-dihexanoyl-3-(7Z,10Z,13Z-hexadecatrienoyl)-glycerol + CoA => (7Z,10Z,13Z)-hexadecatrienoyl-CoA + 1,2-dihexanoylglycerol


name: a quinone + L-proline <=> (S)-1-pyrroline-5-carboxylate + a quinol + H(+)


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Plasmodium falciparum)


name: p-S MAPKAPK5 phosphorylates HSPB1 (Gallus gallus)


name: eicosanoyl-CoA + taurine <=> CoA + H(+) + N-eicosanoyl-taurine


name: 1'-hydroxy-gamma-carotene + A = 1'-hydroxytorulene + AH2


name: OCT2 mediates tubular uptake of organic cations in the kidney (Caenorhabditis elegans)


name: HRH4 binds Hist (Caenorhabditis elegans)


name: Addition of the third nucleotide on the nascent transcript (Caenorhabditis elegans)


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Gallus gallus)


name: Formation of the Spliceosomal E complex (Homo sapiens)


name: Activated JNKs phosphorylate c-JUN (Gallus gallus)


name: Unwinding DNA for the nascent transcript (Caenorhabditis elegans)


name: a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate => a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O


name: Association of procollagen type XXV (Canis familiaris)


name: AKT binds PDPK1 (Caenorhabditis elegans)


name: myo-inositol + phosphate => a myo-inositol phosphate + H2O


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Xenopus tropicalis)


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Bos taurus)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + H(+) + sn-glycerol 3-phosphocholine


name: (R)-rosmarinate + CoA => (2R)-3-(3,4-dihydroxyphenyl)lactate + (E)-caffeoyl-CoA


name: 6-sulfo-D-quinovose + NAD(+) => 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H(+) + NADH


name: Furin cleaves pro-factor IX to factor IX (Gallus gallus)


name: biochanin A 7-O-beta-D-glucoside 6''-O-malonate + CoA => biochanin A 7-O-beta-D-glucoside + malonyl-CoA


name: POU3F1 binds the ZIC2 gene (Homo sapiens)


name: (3E,5S)-3-[(2E,4E,8S,10E,12Z)-1-hydroxy-4,8-dimethyltetradeca-2,4,10,12-tetraen-1-ylidene]-5-[(4-hydroxyphenyl)methyl]pyrrolidine-2,4-dione + O2 + reduced [NADPH--hemoprotein reductase] = 3-[(2E,4E,8S,10E,12Z)-4,8-dimethyltetradeca-2,4,10,12-tetraenoyl]-4-hydroxy-5-(4-hydroxyphenyl)-1,2-dihydropyridin-2-one + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: p-5Y-RET complexes bind GRB2 (Mus musculus)


name: AH2 + O2 + progesterone = 11alpha-hydroxyprogesterone + A + H2O


name: L-leucine(out) + L-lysine(in) + Na(+)(out) = L-leucine(in) + L-lysine(out) + Na(+)(in)


name: H(+) + ilicicolin A epoxide + NADPH + O2 <=> 16-hydroxy-ilicicolin A epoxide + H2O + NADP(+)


name: H(+)(in) + pyruvate(in) => H(+)(out) + pyruvate(out)


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Mus musculus)


name: Transport of processed viral proteins to the cell membrane (Homo sapiens)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Mus musculus)


name: Caspase-mediated cleavage of Z0-2 (Xenopus tropicalis)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Mus musculus)


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 2 A + 3 H2O = [DsrC protein]-dithiol + 2 AH2 + 2 H(+) + sulfite


name: H(+) + 2 H2O2 + hexadecanoate => CO2 + 3 H2O + pentadecanal


name: 2 AH2 + all-trans-adonixanthin + 2 O2 <=> 2 A + all-trans-(3S,3'S)-astaxanthin + 3 H2O


name: (S)-malate(in) + phosphate(out) = (S)-malate(out) + phosphate(in)


name: 3-oxopropanoate + dihydroxyacetone phosphate => 6-phospho-5-dehydro-2-deoxy-D-gluconate


name: The FA anion diffuses away laterally from UCP (Sus scrofa)


name: BP180 interacts intracellularly with plectin and integrin beta4 (Sus scrofa)


name: ATP + O-alkylglycerone = 1-O-alkylglycerone 3-phosphate + ADP + H(+)


name: ergosteryl ester + H2O <=> a carboxylate + ergosterol + H(+)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: ATP + chloramphenicol(in) + H2O <=> ADP + chloramphenicol(out) + H(+) + phosphate


name: RFC dissociates after sliding clamp formation (Canis familiaris)


name: (11R)-dihydroartemisinate + 2 H(+) + NADPH => (11R)-dihydroartemisinic aldehyde + H2O + NADP(+)


name: Activated protein C cleaves factor Va to factor Vi intermediate form (Bos taurus)


name: ADP + H(+) + leukotriene C4(in) + phosphate => ATP + H2O + leukotriene C4(out)


name: 3-methylphenol + O2 + reduced [NADPH--hemoprotein reductase] <=> 3-hydroxybenzyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z,12Z)-octadecadienoate + H2O <=> (12Z)-10-hydroxyoctadecenoate


name: Association of procollagen type XIX (Rattus norvegicus)


name: H2O2 + L-ascorbate = 2 H2O + L-dehydroascorbate


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Dictyostelium discoideum)


name: Formation of Activated Protein 1 (AP-1) complex. ATF2/c-JUN heterodimer.  (Caenorhabditis elegans)


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Sus scrofa)


name: AMPK (complex) phosphorylates ULK1 (complex) (Canis familiaris)


name: CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate (Canis familiaris)


name: ULK complex translocates to the ER (Canis familiaris)


name: PTPRD binds SLITRK1-6 (Rattus norvegicus)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Rattus norvegicus)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-glucose => alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + tryprostatin B <=> 6-hydroxytryprostatin B + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Homo sapiens)


name: Mevalonate-5-phosphate is further phosphorylated. (Caenorhabditis elegans)


name: chloride(out) + glycine(out) + 3 Na(+)(out) = chloride(in) + glycine(in) + 3 Na(+)(in)


name: 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + NAD(+) <=> 3-acetyl-3-devinylchlorophyllide a + H(+) + NADH


name: H(+) + heptan-2-one + NADPH + O2 = H2O + NADP(+) + pentyl acetate


name: Dissociation of the TP:Gq complex (Sus scrofa)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Xenopus tropicalis)


name: RUNX1 binds YAP1 (Caenorhabditis elegans)


name: Na(+)(in) + O-butanoyl-(R)-carnitine(in) => Na(+)(out) + O-butanoyl-(R)-carnitine(out)


name: (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(in) => (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(out)


name: Furin cleaves pro-protein S to protein S (Xenopus tropicalis)


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Caenorhabditis elegans)


name: ATP + H(+) + octanoate = diphosphate + octanoyl-AMP


name: L-lysyl-5'-AMP + tRNA(Lys) => AMP + H(+) + L-lysyl-tRNA(Lys)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate => H2O + isochorismate


name: diphosphate + GDP-D-glycero-alpha-D-manno-heptose => D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+)


name: ADP + ADP <=> AMP + ATP [AK2] (Homo sapiens)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Xenopus tropicalis)


name: GSTZ1 dimer dehalogenates DCA (Bos taurus)


name: Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Rattus norvegicus)


name: 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+) => H2O + L-cysteine + O2


name: agmatine + H2O => N-carbamoylputrescine + NH4(+)


name: Dentin phosphoprotein binds integrin alphaVbeta1 (Mus musculus)


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Canis familiaris)


name: H(+) + methanol + salicylate => H2O + methyl salicylate


name: ADORA2A,B bind Ade-Rib (Caenorhabditis elegans)


name: N-(6-aminohexanoyl)-6-aminohexanoate => 1,8-diazacyclotetradecane-2,9-dione + H2O


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Sus scrofa)


name: a cytidine in RNA + S-adenosyl-L-methionine <=> an N(3)-methylcytidine in RNA + H(+) + S-adenosyl-L-homocysteine


name: Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc (Homo sapiens)


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Homo sapiens)


name: SeMet is converted to AdoSeMet by MAT (Rattus norvegicus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine => 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: 4-carboxy-2-thioxobutanoyl-CoA => 5-hydroxythiophene-2-carbonyl-CoA + H2O


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Xenopus tropicalis)


name: a 1-acyl-sn-glycero-3-phosphate + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: 3-dehydro-L-gulonate 6-phosphate + H(+) = CO2 + L-xylulose 5-phosphate


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Plasmodium falciparum)


name: CTP(out) + ITP(in) => CTP(in) + ITP(out)


name: Aquaporin-3 passively transports water out of cell (Rattus norvegicus)


name: Arachidonic acid is oxidised to 15R-HETE by Acetyl-PTGS2 (Canis familiaris)


name: (S)-indan-1-ol + NADP(+) => H(+) + indan-1-one + NADPH


name: cyclo(L-phenylalanyl-L-leucyl) + O2 => cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + H2O2


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Canis familiaris)


name: 1,2,3-tri-(9Z,12Z,15Z)-octadecatrienoylglycerol + H2O => (9Z,12Z,15Z)-octadecatrienoate + 1,3-di-(9Z,12Z,15Z)-octadecatrienoylglycerol + H(+)


name: an oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> an N-acyl-sphingoid base + an oligoglycosyl-(1->4)-D-glucose


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Xenopus tropicalis)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + D-galactose => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H2O


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate


name: adenosine(58) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + eicosanoyl-CoA + O2 => 2-hydroxyeicosanoyl-CoA + CO2 + succinate


name: [HPr protein]-O-phospho-L-serine + ADP + H(+) => [HPr protein]-L-serine + ATP


name: Activated TLR3:TRIF:K63pUb-TRAF6 recruits TAK1complex (Homo sapiens)


name: Phosphorylated STATs are released (Homo sapiens)


name: 1-(9Z-octadecenoyl)-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O = (9Z)-octadecenoate + 2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-1D-myo-inositol + H(+)


name: miR-26A and B bind to the 3'UTR of the CHD11 mRNA (Homo sapiens)


name: SESN1,2,3 bind overoxidized PRDX1 (Canis familiaris)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Drosophila melanogaster)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Homo sapiens)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Mus musculus)


name: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine = 3',5-dihydroxy-3,4',7-trimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Mus musculus)


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Homo sapiens)


name: 3 H(+) + L-histidine + 2 NADH => H2O + L-histidinol + 2 NAD(+)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Gallus gallus)


name: O2 + tetradecanoyl-CoA => (2E)-tetradecenoyl-CoA + H2O2


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Caenorhabditis elegans)


name: Opsins act as GEFs for G alpha-t (Homo sapiens)


name: SLC25A10 mediates exchange of malate and phosphate (Sus scrofa)


name: 3 H(+) + hexanoyl-CoA + 3 malonyl-CoA = 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine => 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: KAT2 complexes acetylate histone H3 (Homo sapiens)


name: K11-linked polyubiquitin modification-dependent protein binding


name: SUMOylation of Histone H4 with SUMO1 (Danio rerio)


name: H(+) + S-adenosyl-L-homocysteine + xanthotoxin => S-adenosyl-L-methionine + xanthotoxol


name: NAD(+) + pregnenolone = H(+) + NADH + pregn-5-ene-3,20-dione


name: Initial activation of proMMP3 (Bos taurus)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)


name: [(1''->2')-ADP-alpha-D-ribose](n-1) + ADP-D-ribose => [(1''->2')-ADP-alpha-D-ribose](n) + H2O


name: H(+)(in) + pemetrexed(in) <=> H(+)(out) + pemetrexed(out)


name: Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Gallus gallus)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Saccharomyces cerevisiae)


name: 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + H(+) + S-adenosyl-L-homocysteine => 2-sulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine


name: CoA + O-acetyl-(R)-carnitine => (R)-carnitine + acetyl-CoA


name: D-leucine + H2O + O2 <=> 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: mycophenolate + UDP-alpha-D-glucuronate <=> mycophenolic acid O-acyl-beta-D-glucuronide + UDP


name: HLCS biotinylates 6xMCCC1:6xMCCC2 (Drosophila melanogaster)


name: PEX3:PEX19:class I PMP dissociates (Canis familiaris)


name: voltage-gated sodium channel activity involved in cardiac muscle cell action potential


name: RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex (Homo sapiens)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[protein] => acetyl-CoA + N-terminal L-alanyl-[protein]


name: 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) <=> acenaphthene-1,2-dione + 2 H(+) + 2 NADPH


name: PG transports from the ER membrane to the late endosome membrane (Homo sapiens)


name: ALK binds ligand midkine (MDK) (Sus scrofa)


name: 22-hydroxydocosanoate + O2 + reduced [NADPH--hemoprotein reductase] => 22-oxodocosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) (Homo sapiens)


name: H(+) + NADPH + testosterone => 17beta-hydroxy-5alpha-androstan-3-one + NADP(+)


name: Active ALK phosphorylates IRS1 (Homo sapiens)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + H2O


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: 17beta-estradiol + AH2 + O2 <=> 6beta-hydroxyestradiol-17beta + A + H2O


name: (E)-ferulate + ATP + CoA <=> (E)-feruloyl-CoA + AMP + diphosphate


name: 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + 2 H(+) + 2 S-adenosyl-L-homocysteine => 2 S-adenosyl-L-methionine + squalene


name: 4 glutathione + 2 H(+) + selenite => glutathione disulfide + 3 H2O + selenodiglutathione


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Bos taurus)


name: L-tyrosine = 2-aminoprop-2-enoate + phenol


name: SESN1,2,3 bind overoxidized PRDX1 (Dictyostelium discoideum)


name: Association of procollagen type XXII (Sus scrofa)


name: KCNH2:KCNE transport K+ from cytosol to extracellular region (Canis familiaris)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Mus musculus)


name: Cytosolic PER is degraded by the 26S proteasome (Drosophila melanogaster)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Homo sapiens)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Mus musculus)


name: a nucleoside 5'-phosphate + ATP = a 5'-phosphonucleoside 3'-diphosphate + AMP + H(+)


name: FAR2 reduces PalmCoA to HXOL (Dictyostelium discoideum)


name: CUL3:RBX1 ubiquitinates KEAP1 (Gallus gallus)


name: PTPN1 and PTPN2 dephosphorylate MET (Bos taurus)


name: Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Mus musculus)


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)


name: hydroquinone + UDP-alpha-D-glucose => H(+) + hydroquinone O-beta-D-glucopyranoside + UDP


name: Fusion of ERC and phagosome (Homo sapiens)


name: AURKA phosphorylates PHLDA1 (Bos taurus)


name: dehydroepiandrosterone 3-sulfate(out) + pentanoate(in) => dehydroepiandrosterone 3-sulfate(in) + pentanoate(out)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Mus musculus)


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O => 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-octanoylsphinganine + O2 = 2 Fe(III)-[cytochrome b5] + H2O + N-octanoyl-4-hydroxysphinganine


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Sus scrofa)


name: 3''-hydroxygeranylhydroquinone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => geranylhydroquinone + O2 + reduced [NADPH--hemoprotein reductase]


name: CTP(in) + dGTP(out) => CTP(out) + dGTP(in)


name: MUS81:EME1,EME2 cleaves D-loop (Canis familiaris)


name: arginine + H2O => ornithine + urea [ARG1] (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol = 1'-[1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Rattus norvegicus)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Rattus norvegicus)


name: 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + S-adenosyl-L-methionine <=> H(+) + plastoquinol-9 + S-adenosyl-L-homocysteine


name: dioctanoylglycerol + H(+) + octanoate => 1,2,3-trioctanoylglycerol + H2O


name: PIAS1 SUMOylates DDX5 with SUMO2 (Rattus norvegicus)


name: (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH => D-glyceraldehyde 3-phosphate + NAD(+) + phosphate


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP + CoA


name: TRAF6 binds MALT1 oligomers (Sus scrofa)


name: 26-hydroxyhexacosanoate + NAD(+) <=> 26-oxohexacosanoate + H(+) + NADH


name: Dissociation of IRS-P from insulin receptor (Canis familiaris)


name: RAC1 GAPs stimulate RAC1 GTPase activity (Bos taurus)


name: PTGS2 dimer binds PTGS2 inhibitors (Homo sapiens)


name: Autophosphorylation of PAK (Homo sapiens)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Gallus gallus)


name: all-trans-retinyl hexadecanoate + H2O => 11-cis-retinol + H(+) + hexadecanoate


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Caenorhabditis elegans)


name: USP20, USP33 deubiquitinate ADRB2 (Drosophila melanogaster)


name: CMP + H(+) + sphing-4-enine-phosphocholine => CDP-choline + sphing-4-enine


name: (2E,6E)-farnesyl diphosphate + H2O <=> (1S,6S,7R)-sesquipiperitol + diphosphate


name: HP1 alpha binds Histone H3K9(me)3 (Sus scrofa)


name: Formation of hydroxylysyl-pyrrole cross-links (Sus scrofa)


name: Ubiquitination of stimulated EGFR (CBL) (Mus musculus)


name: AMP + cremeomycin + diphosphate + H2O => 3-amino-2-hydroxy-4-methoxybenzoate + ATP + nitrite


name: (R)-mevalonate + NAD(+) => (R)-mevaldate + H(+) + NADH


name: H2O + L-glutamate 5-semialdehyde + NADP(+) => 2 H(+) + L-glutamate + NADPH


name: mycinamicin VI + S-adenosyl-L-methionine = H(+) + mycinamicin III + S-adenosyl-L-homocysteine


name: ITPA hydrolyses dITP to dIMP (Homo sapiens)


name: (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA + NADP(+)


name: a 2'-deoxyadenosine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + O2


name: (9Z)-octadecenoate + H(+) + sn-glycero-3-phospho-1D-myo-inositol => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: A + H2O + isoquinoline = AH2 + isoquinolin-1(2H)-one


name: PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Mus musculus)


name: a 16beta-hydroxysteroid => a 16alpha-hydroxysteroid


name: ribonucleoside triphosphate phosphatase activity


name: 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al => 4 H(+) + 2 O2 + pentalenene + 4 reduced [2Fe-2S]-[ferredoxin]


name: anthraniloyl-CoA + methanol => CoA + O-methyl anthranilate


name: Protesomal degradation of K48polyUb-TRAF3 (Rattus norvegicus)


name: cytidine(out) + H(+)(out) => cytidine(in) + H(+)(in)


name: Na+/H+ exchanger transport (at cell membrane) (Bos taurus)


name: SMAD7 binds to SMURF2 (Drosophila melanogaster)


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Plasmodium falciparum)


name: 2',3'-cGAMP + 2 diphosphate => ATP + GTP


name: 2 S-adenosyl-L-methionine + sphing-4-enine = 2 H(+) + N,N-dimethylsphing-4-enine + 2 S-adenosyl-L-homocysteine


name: Dephosphorylation of AKT by PP2A (Caenorhabditis elegans)


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Rattus norvegicus)


name: O2 + prostaglandin E2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy prostaglandin E2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TGFBR2 phosphorylates TGFBR1 (Bos taurus)


name: a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine


name: TP53 family members bind the CASP1 gene (Homo sapiens)


name: (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + H(+) + succinate


name: p62 links damaged mitochondria to LC3 (Homo sapiens)


name: (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + lochnericine + oxidized [NADPH--hemoprotein reductase]


name: p-STAT1 dissociates from IL6ST:IL6ST (Bos taurus)


name: H2O + psi-UMP => phosphate + pseudouridine


name: ACY3:Zn2+ dimer hydrolyses mercapturic acids (Homo sapiens)


name: ATP + H2O + spermine(out) => ADP + H(+) + phosphate + spermine(in)


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Drosophila melanogaster)


name: ALDHs oxidise atRAL to atRA (Danio rerio)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Drosophila melanogaster)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Bos taurus)


name: Interaction of Tie2 and Shc1 (Canis familiaris)


name: (S)-tetrahydropalmatine + S-adenosyl-L-methionine <=> (S)-cis-N-methyltetrahydropalmatine + S-adenosyl-L-homocysteine


name: 3-oxoisoapionate 4-phosphate + H2O = (2R)-3-phosphoglycerate + glycolate + H(+)


name: (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Canis familiaris)


name: Formation of ERCC1:XPF heterodimeric complex (Rattus norvegicus)


name: 4-methyl-2-oxopentanoate + H(+) <=> 3-methylbutanal + CO2


name: beta-D-gentiobiosyl crocetin + UDP-alpha-D-glucose = beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP


name: 3-hydroxy-4-methylanthranilate + H(+) + S-adenosyl-L-homocysteine => 3-hydroxyanthranilate + S-adenosyl-L-methionine


name: NAD(+) + pregnan-21-ol <=> H(+) + NADH + pregnan-21-al


name: MT-MMPs are sorted to the plasma membrane (Drosophila melanogaster)


name: PKC phosphorylates NCF1 (Saccharomyces cerevisiae)


name: 3-aminobutan-2-ol + H2O + NADP(+) <=> acetoin + H(+) + NADPH + NH4(+)


name: OTUD3 deubiquitinates PTEN (Canis familiaris)


name: UDP(in) + UDP-alpha-D-glucuronate(out) = UDP(out) + UDP-alpha-D-glucuronate(in)


name: docosanoyl-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = AMP + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + H(+)


name: CES1,CES2 hydrolyze ASA- to ST (Homo sapiens)


name: methyl-Co(III)-[methylamine-specific corrinoid protein] + NH4(+) => Co(I)-[methylamine-specific corrinoid protein] + H(+) + methylamine


name: p-SLP-76 binds NCK (Drosophila melanogaster)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Dictyostelium discoideum)


name: H2O + propanamide => NH4(+) + propanoate


name: EGR2 and SREBF2 dimer bind CYP51A1 gene (Homo sapiens)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Mus musculus)


name: (4Z,15Z)-bilirubin IXalpha + 4 AH2 => 4 A + urobilinogen


name: dodecanoyl-CoA + H2O => adenosine 3',5'-bisphosphate + 2 H(+) + S-dodecanoyl-4'-phosphopantetheine


name: an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + H2O => 3-methylcytosine + a 2'-deoxyribose 5'-phosphate in double-stranded DNA + H(+)


name: 9-cis-retinyl tetradecanoate + CoA => 9-cis-retinol + tetradecanoyl-CoA


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Caenorhabditis elegans)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Sus scrofa)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Mus musculus)


name: 2-AG hydrolysis to arachidonate by MAGL (Saccharomyces cerevisiae)


name: DHRS7B reduces GO3P to HXDG3P (Xenopus tropicalis)


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Xenopus tropicalis)


name: dihydroorotate dehydrogenase (fumarate) activity


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Drosophila melanogaster)


name: CPTP transports C1P from plasma membrane to Golgi membrane (Bos taurus)


name: betaine aldehyde + H(+) + NADH => choline + NAD(+)


name: Dephosphorylation of JAK1 by SHP1 (Homo sapiens)


name: (2E,23Z,26Z,29Z,32Z)-octatriacontapentaenoyl-CoA + H2O => (3R)-hydroxy-(23Z,26Z,29Z,32Z)-octatriacontatetraenoyl-CoA


name: 8-O-methyldihydrosterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => aflatoxin B2 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase]


name: oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor


name: Carbonic anhydrase hydrates carbon dioxide (cytosol) (Mus musculus)


name: laricitrin + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + syringetin


name: ATP + N-acetyl-L-glutamate <=> ADP + N-acetyl-L-glutamyl 5-phosphate


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine


name: HLCS biotinylates 6xMCCC1:6xMCCC2 (Bos taurus)


name: an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O => an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Homo sapiens)


name: 25-hydroxyvitamin D3 sulfate(out) + n H(+)(out) => 25-hydroxyvitamin D3 sulfate(in) + n H(+)(in)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine <=> 4-O-([2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: PTK6 phosphorylates CDKN1B (Rattus norvegicus)


name: Activated TP receptor binds G-protein  G13 (Gallus gallus)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Homo sapiens)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Homo sapiens)


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Plasmodium falciparum)


name: L-olivosyl-oleandolide + S-adenosyl-L-methionine => H(+) + L-oleandrosyl-oleandolide + S-adenosyl-L-homocysteine


name: [Rab1 protein]-O(4)-(5'-adenylyl)-L-tyrosine + H2O => [Rab1 protein]-L-tyrosine + AMP + H(+)


name: PIAS4 SUMOylates VDR with SUMO2 (Gallus gallus)


name: ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE (Dictyostelium discoideum)


name: CTP + UTP => cyclic CMP-UMP + 2 diphosphate


name: PSMD14 cleaves K63-linked ubiquitin (Caenorhabditis elegans)


name: Luteinizing hormone receptor can bind LH (Sus scrofa)


name: fumarate(out) + 3 Na(+)(out) = fumarate(in) + 3 Na(+)(in)


name: H2O + tridodecanoylglycerol <=> 2,3-didodecanoyl-sn-glycerol + dodecanoate + H(+)