name: glycylglycyl-L-proline(in) + H(+)(in) => glycylglycyl-L-proline(out) + H(+)(out)


name: Activated FGFR4 phosphorylates SHC1 (Drosophila melanogaster)


name: Dimerization of sSCF (Xenopus tropicalis)


name: histone H3K36 trimethyltransferase activity


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Drosophila melanogaster)


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Homo sapiens)


name: Association of procollagen type IV (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + A + 2 H2O => AH2 + O2 + octadecanoyl-CoA


name: Interaction of PECAM-1 and SHP-1 (Bos taurus)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] = 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin]


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Dictyostelium discoideum)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Sus scrofa)


name: 3'-AMP(in) + phosphate(out) => 3'-AMP(out) + phosphate(in)


name: (R)-pantothenate + H2O <=> (R)-pantoate + beta-alanine


name: PGH2 is isomerised to PGD2 by PTGDS (Sus scrofa)


name: Autocatalytic phosphorylation of FGFR2c (Mus musculus)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPC (Gallus gallus)


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Bos taurus)


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Dictyostelium discoideum)


name: (2E,6E,10E)-geranylgeranyl diphosphate => cattleyene + diphosphate


name: GRIK3 homomer binds glutamate (Drosophila melanogaster)


name: SENP1,2,5 proteolytically process SUMO1 (Schizosaccharomyces pombe)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate


name: 3-dehydro-6-deoxo-28-norteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 6-dehydro-28-norteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Caenorhabditis elegans)


name: LONP1 degrades mitochondrial matrix proteins (Schizosaccharomyces pombe)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds STAT5 (Homo sapiens)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Gallus gallus)


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Sus scrofa)


name: (R)-carnitine + acetyl-CoA = CoA + O-acetyl-(R)-carnitine


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Dictyostelium discoideum)


name: SLC17A3-2 transports cytosolic urate to extracellular region (Homo sapiens)


name: CYTH proteins stimulate ARF1 GTPase activity (Homo sapiens)


name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Xenopus tropicalis)


name: guanidinoacetate + S-adenosyl-L-methionine => creatine + H(+) + S-adenosyl-L-homocysteine


name: PIAS1,3 SUMOylate ESR1 with SUMO1 (Rattus norvegicus)


name: dodecanoate + sphinganine => H2O + N-(dodecanoyl)-sphinganine


name: Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Xenopus tropicalis)


name: Translation of p16INK4A mRNA is inhibited by miR-24 (Homo sapiens)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + H2O <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + phosphate


name: TBC1D14 binds RAB11 and ULK1 (Mus musculus)


name: TFAP2A:TFAP2C, POU5F1, SOX2 and MYB bind the PAX7 gene (Homo sapiens)


name: Activation of TWIK-related K+ channel (TREK) (Rattus norvegicus)


name: ARHGAP35 stimulates RHOA GTPase activity (Danio rerio)


name: NAD(+) + tetracosanoyl-CoA => (2E)-tetracosenoyl-CoA + H(+) + NADH


name: PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: H(+) + N(1)-methylpseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-homocysteine => pseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-methionine


name: DENND5A,B exchange GTP for GDP on RAB39 (Mus musculus)


name: 2 caldariellaquinol + n H(+)(in) + O2 = 2 caldariellaquinone + n H(+)(out) + 2 H2O


name: RHOT2 hydrolyzes GTP (Rattus norvegicus)


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Homo sapiens)


name: AMP + H(+) + octadecanoyl-[(hydroxy)phthioceranic acid synthase] => holo-[(hydroxy)phthioceranic acid synthase] + octadecanoyl-AMP


name: Sema3A binds Nrp-1 bound to PlexinA (Mus musculus)


name: Ub-RibC-AXIN is degraded by the proteasome (Mus musculus)


name: Activated FGFR2 phosphorylates PPTN11 (Mus musculus)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Canis familiaris)


name: "diadenosine hexaphosphate hydrolase (AMP-forming)"


name: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O => 5alpha-cholestane-3beta,5,6beta-triol


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Canis familiaris)


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Sus scrofa)


name: JAK2 phosphorylation of GHR (Mus musculus)


name: SHC1-2 bound to MET recruits GRB2:SOS1 (Bos taurus)


name: CDK1 phosphorylates BORA (Gallus gallus)


name: IL4:IL4R:JAK2 binds IL13RA1:TYK2 (Homo sapiens)


name: Formation of translation initiation complexes containing mRNA that does not circularize (Rattus norvegicus)


name: alpha-D-mannose 1-phosphate + GDP + H(+) <=> GDP-alpha-D-mannose + phosphate


name: cellulose 1,4-beta-cellobiosidase activity (reducing end)


name: 2,6-dichlorohydroquinone + FADH2 + O2 => 2-chloro-6-hydroxy-1,4-benzoquinone + chloride + FAD + 2 H(+) + H2O


name: (2S,3R)-capreomycidine + H2O => (2S,3S)-hydroxyarginine


name: Cytosolic DUSPs dephosphorylate MAPKs (Drosophila melanogaster)


name: allocholoyl-CoA + deoxycholate => allocholate + deoxycholoyl-CoA


name: H(+) + hexanoyl-CoA + oxidized [electron-transfer flavoprotein] => (2E)-hexenoyl-CoA + reduced [electron-transfer flavoprotein]


name: acetophenone + H(+) + NADPH <=> (R)-1-phenylethanol + NADP(+)


name: (9Z)-tetradecenoyl-CoA + (R)-carnitine <=> CoA + O-(9Z)-tetradecenoyl-(R)-carnitine


name: Caspase-mediated cleavage of Etk (Gallus gallus)


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Homo sapiens)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + stellata-2,6,19-triene <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + stellatate


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Caenorhabditis elegans)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: SARS-CoV-2 3CLpro dimer cleaves NLRP12 (Homo sapiens)


name: ALAD condenses 2 dALAs to form PBG (Drosophila melanogaster)


name: acetoacetate + L-alanine => 3-aminobutanoate + pyruvate


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Dictyostelium discoideum)


name: MITF-M-dependent ATP6V1G1gene expression (Homo sapiens)


name: H2O + O2 + S-(2E,6E)-farnesyl-L-cysteine <=> (2E,6E)-farnesal + H2O2 + L-cysteine


name: Auto-ubiquitination of TRAF6 (Canis familiaris)


name: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate


name: SEMA4D interacts with CD45 (Canis familiaris)


name: 5-aminomethyl-2-thiouridine(34) in tRNA + S-adenosyl-L-methionine <=> 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: CO2 + N-(hydroxymethyl)urea + 2 NH4(+) => 2 H(+) + 2 H2O + methylenediurea


name: H2O + L-gulono-1,4-lactone => H(+) + L-gulonate


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Caenorhabditis elegans)


name: L-aspartate(out) + L-tyrosine(in) => L-aspartate(in) + L-tyrosine(out)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: chlorophyllide b + 3 H2O + 2 NADP(+) => chlorophyllide a + 2 H(+) + 2 NADPH + 2 O2


name: 2-acyl LPE is acylated to PE by LPEAT (Saccharomyces cerevisiae)


name: H2O + N-hexadecanoyl-(4R)-hydroxysphinganine = (4R)-hydroxysphinganine + hexadecanoate


name: Interleukin-12 dissociates from Interleukin-12 receptor (Gallus gallus)


name: ATP + CoA + hexadecanoate => AMP + diphosphate + hexadecanoyl-CoA


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + H2O = (9Z,12Z,15Z)-octadecatrienoate + glycerol + H(+)


name: (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + CO2 + CoA


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Mus musculus)


name: Interaction of GPVI and FceRI gamma (Mus musculus)


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Bos taurus)


name: ADP + cyclic (2R)-2,3-bisphosphoglycerate + phosphate => (2R)-2,3-bisphosphoglycerate + ATP + H(+)


name: acetate + androst-4-ene-3,17-dione + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase]


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Canis familiaris)


name: p-S407,Y641-STAT6 is dimerized (Caenorhabditis elegans)


name: 3 a ubiquinol(in) + 2 H(+)(out) + nitrite(out) => 3 a ubiquinone(in) + 2 H2O(out) + NH4(+)(out)


name: beta-D-Delta(4)-GlcA-(1->4)-beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc + H2O => 5-dehydro-4-deoxy-D-glucuronate + beta-D-Glc-(1->4)-alpha-L-Rha-(1->3)-D-Glc


name: Cytosolic PLK1 translocates to the nucleus (Xenopus tropicalis)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Dictyostelium discoideum)


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Schizosaccharomyces pombe)


name: PTGIS, CYP8A1 isomerise PGH2 to PGI2 (Canis familiaris)


name: Dephosphorylation of CK2-modified condensin I (Schizosaccharomyces pombe)


name: Dephosphorylation of p107 (RBL1) by PP2A (Danio rerio)


name: 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH => deoxycholate + NADP(+)


name: 1-O-alkyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-alkyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: (10E)-octadecenoate + H2O = 10-hydroxyoctadecanoate


name: RNF43 frameshift mutants show enhanced WNT siganling (Homo sapiens)


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Xenopus tropicalis)


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)


name: UDP-N-acetyl-alpha-D-glucosamine <=> H2O + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose


name: interleukin-1 type I receptor antagonist activity


name: CDH11 nascent mRNA is spliced into the canonical splicing isoform (Homo sapiens)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 <=> (8R)-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Xenopus tropicalis)


name: Integrator complex processes the 3' end of snRNA (Sus scrofa)


name: 3-chloro-D-alanine <=> 2-aminoprop-2-enoate + chloride + H(+)


name: (R)-lanthionine ketimine + 2 H(+) + NADPH = (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Gallus gallus)


name: CO binds to Cytochrome c oxidase (Rattus norvegicus)


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Sus scrofa)


name: CYP19A1 binds Aromatase inhibitors (Rattus norvegicus)


name: alpha-D-galactose 1-phosphate + dTTP + H(+) => diphosphate + dTDP-D-galactose


name: gastric inhibitory peptide receptor activity


name: USP16,USP21 deubiquitinate Histone H2A (Sus scrofa)


name: A + semiviriditoxin => AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc6S derivative + GDP-beta-L-fucose <=> an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc6S derivative + GDP + H(+)


name: devancoaminyl-vancomycin + dTDP-beta-L-vancosamine => dTDP + H(+) + vancomycin


name: at-retinyl is hydrolysed from p-MII:SAG to release atRAL (Gallus gallus)


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Gallus gallus)


name: Active ALK phosphorylates SHC1 (Gallus gallus)


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + ATP + CoA => 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: Arachidonic acid is oxidised to 12R-HpETE by ALOX12B (Homo sapiens)


name: Transport of the Mature IntronlessTranscript Derived Histone mRNA:SLBP:TAP:Aly/Ref complex through the NPC (Canis familiaris)


name: 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] => 17beta,18-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 3-hexadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol) = 3-hexadecanoyl-sn-glycero-1-phospho-(3'-hexadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)


name: (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+) => (2R,3R)-dihydroquercetin + H(+) + NADPH + O2


name: factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) (Danio rerio)


name: 2,4,6-trichlorophenol + FADH2 + O2 => 2,6-dichlorobenzoquinone + chloride + FAD + H(+) + H2O


name: (-)-trans-permethrin + H2O = (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate + (3-phenoxyphenyl)methanol + H(+)


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Gallus gallus)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)


name: RHOGAPP190 binds to RHO1:GTP complex at the plasma membrane (Drosophila melanogaster)


name: 4-coumaroyl-CoA + 2 H(+) + 3 malonyl-CoA => 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoA


name: H(+) + NADH + O2 + phenol => H2O + hydroquinone + NAD(+)


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Caenorhabditis elegans)


name: atROL binds RBP1 (parenchymal cell) (Bos taurus)


name: RRAGC,D exchanges GTP for GDP (Drosophila melanogaster)


name: a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol


name: MAP2K6 phosphorylates PIP4K2B (Gallus gallus)


name: 2 H2O + L-cystine-bis-glycine <=> 2 glycine + L-cystine


name: L-ascorbate(out) + N(pros)-phospho-L-histidyl-[protein] => L-ascorbate 6-phosphate(in) + L-histidyl-[protein]


name: a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)


name: Association of procollagen type III (Canis familiaris)


name: MDM2 ubiquitinates JMY (Canis familiaris)


name: 10R-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate => (6Z,9Z,12Z)-octadecatrienoate + O2


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: p-TARBP2 binds PKR (Caenorhabditis elegans)


name: beta-alanine + L-histidine => carnosine + H2O


name: L-erythro-N-acylsphing-4-enine + UDP-alpha-D-glucose <=> beta-D-glucosyl-L-erythro-N-acylsphing-4-enine + H(+) + UDP


name: cyclo(L-tryptophyl-L-alanyl) + dimethylallyl diphosphate => diphosphate + preechinulin


name: H(+)(out) + L-alanyl-L-lysine(out) => H(+)(in) + L-alanyl-L-lysine(in)


name: Unphosphorylated nucleoprotein translocates to the plasma membrane (Homo sapiens)


name: borneol + NAD(+) => camphor + H(+) + NADH


name: a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+) => a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Schizosaccharomyces pombe)


name: MBTPS2 (S2P) cleaves CREB3L3 (Sus scrofa)


name: FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Homo sapiens)


name: natural killer cell lectin-like receptor binding


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Rattus norvegicus)


name: NICD1 in complex with RBPJ (CSL) recruits MAML (Gallus gallus)


name: protein ADP-ribosyltransferase-substrate adaptor activity


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2 H2O <=> 2 (9Z)-octadecenoate + 2 H(+) + sn-glycerol 3-phosphocholine


name: 7,8-dihydroneopterin 3'-triphosphate = 7,8-dihydromonapterin 3'-triphosphate


name: kaempferol 3-O-beta-D-glucoside + malonyl-CoA = CoA + kaempferol 3-O-(6-O-malonyl-beta-D-glucoside)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ATP + L-glutamate = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + H(+) + phosphate


name: MAGED1 binds NPAS4 (Drosophila melanogaster)


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Xenopus tropicalis)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Bos taurus)


name: S1PR1 binds S1PR1 agonists (Gallus gallus)


name: a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione => a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Mus musculus)


name: TCN1 binds correnoids in the circulation (Homo sapiens)


name: (Z)-3-ureidoacrylate + H2O => (Z)-3-aminoacrylate + carbamate + H(+)


name: ATP + docosanoate + H(+) <=> diphosphate + docosanoyl-AMP


name: Conversion of C4 into C4a and C4b (Canis familiaris)


name: PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins (Sus scrofa)


name: CYP2A13 oxidises AFM1 to AFM1E (Canis familiaris)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Drosophila melanogaster)


name: alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-ribulose 5-phosphate = D-xylulose 5-phosphate


name: 3'-phosphoadenylyl sulfate + dopamine <=> adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + H(+)


name: a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-[(6Z,9Z,12Z,15Z)-octadectetraenoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: FMNH2 + N-acetyl-S-methyl-L-cysteine + O2 = (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: Expression U2 small nuclear ribonucleoprotein A' (Homo sapiens)


name: MIB2 binds RIPK1 within TNF-α:TNFR1:TRADD:RIPK1:TRAF2 (Xenopus tropicalis)


name: hexanoyl-[ACP] + NADP(+) => (2E)-hexenoyl-[ACP] + H(+) + NADPH


name: H(+) + S-adenosyl-L-methionine <=> CO2 + S-adenosyl 3-(methylsulfanyl)propylamine


name: myricetin + S-adenosyl-L-methionine = H(+) + laricitrin + S-adenosyl-L-homocysteine


name: Connexin 45/Connexin 36 mediated neuronal gap junction communication (Homo sapiens)


name: glutamine + pyruvate => 2-oxoglutaramate + alanine (Rattus norvegicus)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Mus musculus)


name: a 3-acyl-sn-glycerol + a fatty acid + H(+) => a 2,3-diacyl-sn-glycerol + H2O


name: 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + H(+) + NADH => 4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NAD(+)


name: (2E)-2-butenoate + ATP + holo-[ACP] = (2E)-butenoyl-[ACP] + AMP + diphosphate


name: AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Dictyostelium discoideum)


name: VLDL translocates from SER lumen to extracellular region (Gallus gallus)


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Schizosaccharomyces pombe)


name: Dephosphorylation of Gab1 by SHP2 (Bos taurus)


name: snRNA Cap hypermethylation (Mus musculus)


name: beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp + H2O = alpha-D-mannopyranose + beta-D-mannopyranosyl-(1->2)-D-mannopyranose


name: RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Drosophila melanogaster)


name: a 3-carboxymethyl-3-hydroxyacyl-[ACP] => a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H2O


name: mogrol + UDP-alpha-D-glucose => H(+) + mogroside IE + UDP


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Danio rerio)


name: (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+) => D-allo-isoleucine + H2O + O2


name: guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(2251) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: STARD10 transports PC from ER membrane to lamellar body membrane (Homo sapiens)


name: CO2 + H(+) + heptanal + succinate + sulfate => 2-oxoglutarate + heptyl sulfate + O2


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Rattus norvegicus)


name: 5,6-dihydrouridine(47) in tRNA + NADP(+) <=> H(+) + NADPH + uridine(47) in tRNA


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine <=> 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP


name: DAG is metabolized by DAGL to 2-AG (Bos taurus)


name: EPH receptors autophosphorylate (Gallus gallus)


name: SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors (Homo sapiens)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Bos taurus)


name: MRN activates ATM (Dictyostelium discoideum)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Mus musculus)


name: 5-HEDH dehydrogenates 7-HDHA to 7-oxo-DHA (Homo sapiens)


name: KIBRA (WWC1) binds LATS proteins (Mus musculus)


name: TP53 binds the AIFM2 gene promoter (Homo sapiens)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Bos taurus)


name: HuR:mRNA complex translocates from the nucleus to the cytosol (Rattus norvegicus)


name: cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 <=> albonoursin + H2O2


name: dibenzothiophene 5-oxide + FMNH2 + O2 <=> dibenzothiophene 5,5-dioxide + FMN + H(+) + H2O


name: Extracellular KSPG translocates to the lysosome for degradation (Canis familiaris)


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Caenorhabditis elegans)


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Rattus norvegicus)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate = 1,3-di-(9Z-octadecenoyl)-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: trichloro-p-hydroquinone reductive dehalogenase activity


name: a fatty acyl-CoA + a long chain fatty alcohol => a wax ester + CoA


name: RHOA binds effectors at the plasma membrane (Xenopus tropicalis)


name: an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate


name: H2O + N'-monoacetylchitobiose-6'-phosphate <=> D-glucosamine + N-acetyl-D-glucosamine 6-phosphate


name: H(+) + N(4)-aminopropylspermidine + S-methyl-5'-thioadenosine => S-adenosyl 3-(methylsulfanyl)propylamine + spermidine


name: (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O => (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose


name: diisopropyl phosphate + fluoride + 2 H(+) => diisopropyl fluorophosphate + H2O


name: Internalisation of the insulin receptor (Homo sapiens)


name: chloride(out) + L-tyrosine(out) + 2 Na(+)(out) => chloride(in) + L-tyrosine(in) + 2 Na(+)(in)


name: cis-1,2-dithiane-4,5-diol + 2 H(+) + hydrogen sulfide + sulfite => dithioerythritol + thiosulfate


name: SUMOylation of HIPK2 with SUMO1 (Saccharomyces cerevisiae)


name: ALOX5 oxidises DHA to 7-HDHA (Dictyostelium discoideum)


name: cyclohexanone + H(+) + NADH + NH4(+) => cyclohexylamine + H2O + NAD(+)


name: MLCL is acylated to CL by LCLAT1 (ER) (Bos taurus)


name: ATP + glycyl-[methyl-coenzyme M reductase] + hydrogen sulfide <=> ADP + phosphate + thioglycyl-[methyl-coenzyme M reductase]


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Bos taurus)


name: The Ligand:GPCR:Gi complex dissociates (Bos taurus)


name: D-galactose + NAD(+) = D-galactono-1,4-lactone + H(+) + NADH


name: RHAG transports CO2 from extracellular region to cytosol (Rattus norvegicus)


name: Nucleotide exchange on RAB1 (Drosophila melanogaster)


name: (3R)-3-hydroxypentanoyl-CoA + H2O = (3R)-3-hydroxypentanoate + CoA + H(+)


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Sus scrofa)


name: Autocatalytic phosphorylation of FGFR1b (Canis familiaris)


name: (+)-lariciresinol + NADP(+) => (+)-pinoresinol + H(+) + NADPH


name: MME:Zn2+ binds sacubitrilat (Caenorhabditis elegans)


name: ANOs transport cytosolic Cl- to extracellular region (Canis familiaris)


name: Type X collagen associates with collagen type II fibrils (Sus scrofa)


name: Unknown kinase phosphorylates nucleoprotein (Homo sapiens)


name: SEPHS2 phosphorylates H2Se to form SELP (Drosophila melanogaster)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Gallus gallus)


name: (+)-copalyl diphosphate + H2O <=> diphosphate + manool


name: Luteinizing hormone receptor can bind LH (Mus musculus)


name: "protoporphyrinogen IX dehydrogenase (quinone)"


name: EVL:PPL heterodimer binds the inner surface of the plasma membrane (Bos taurus)


name: p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP (Homo sapiens)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-a (Mus musculus)


name: eicosanoyl-CoA + sphing-4-enine <=> CoA + H(+) + N-eicosanoyl-sphing-4-enine


name: Phosphorylation of EGFR by SRC kinase (Bos taurus)


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Gallus gallus)


name: Cleavage of ethenocytosine by TDG glycosylase  (Canis familiaris)


name: ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA (Canis familiaris)


name: 2 H2O + L-1-piperideine-6-carboxylate + NAD(+) <=> H(+) + L-2-aminoadipate + NADH


name: H(+)(in) + sucrose(out) <=> H(+)(out) + sucrose(in)


name: 21S rRNA pseudouridine(2819) synthase activity


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Gallus gallus)


name: D-dopa + H2O + O2 => 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: at-retinyl is hydrolysed from p-MII:SAG to release atRAL (Caenorhabditis elegans)


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Xenopus tropicalis)


name: SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Xenopus tropicalis)


name: AMP + H2O => adenine + D-ribose 5-phosphate


name: anisole + O2 + reduced [NADH--hemoprotein reductase] = formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase] + phenol


name: Thrombin binding to GP1b:IX:V (Bos taurus)


name: ATP + hygromycin B <=> 7''-O-phosphohygromycin B + ADP + H(+)


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Mus musculus)


name: Initiation of SAHF formation (Bos taurus)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Sus scrofa)


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Rattus norvegicus)


name: SLC16A10-mediated uptake of aromatic amino acids (Sus scrofa)


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Xenopus tropicalis)


name: CTP + UTP = cyclic CMP-UMP + 2 diphosphate


name: UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG (Homo sapiens)


name: Excision of FapyG by OGG1 glycosylase (Dictyostelium discoideum)


name: 2-oxoglutarate + glutarate + O2 <=> (S)-2-hydroxyglutarate + CO2 + succinate


name: SEMA4D interacts with Plexin-B1:ErbB2 (Canis familiaris)


name: CYP2E1 monooxygenates APAP to NAPQI (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA <=> (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: RAC2 binds effectors at the phagocytic vesicle membrane (Mus musculus)


name: NRF1:PPARGC1B binds the CYCS promoter (Homo sapiens)


name: [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Danio rerio)


name: H2O + sn-glycero-3-phospho-(1'-rac-glycerol) <=> glycerol + H(+) + sn-glycerol 3-phosphate


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Bos taurus)


name: I(1,4,5)P3 binds ITPR3 tetramer (Homo sapiens)


name: P2Y14 receptor can bind to UDP-glucose (Xenopus tropicalis)


name: Unwinding of DNA for the Nascent Transcript: Second Transition (Schizosaccharomyces pombe)


name: 2 H(+) + O2 + pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-ol


name: (E,E)-piperate + ATP + H(+) <=> (E,E)-piperoyl-AMP + diphosphate


name: SPHK1 phosphorylates sphingoid (Schizosaccharomyces pombe)


name: Formation of lysyl-pyrrole cross-links (Bos taurus)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Schizosaccharomyces pombe)


name: 3beta-hydroxyandrost-5-en-17-one + H(+) + NADPH <=> androst-5-en-3beta,17beta-diol + NADP(+)


name: oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor


name: SUMOylation of RAD52 with SUMO1 (Sus scrofa)


name: a ganglioside GT1a + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b + CMP + H(+)


name: (S)-reticuline + S-adenosyl-L-methionine => (S)-laudanine + H(+) + S-adenosyl-L-homocysteine


name: Recruited STAT5 is phosphorylated (Canis familiaris)


name: 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + ADP + H(+) => ATP + D-cellobiose


name: NICD4 traffics to the nucleus (Sus scrofa)


name: RHOD binds effectors at the Golgi membrane (Canis familiaris)


name: L-leucine(out) + L-lysine(in) + Na(+)(out) => L-leucine(in) + L-lysine(out) + Na(+)(in)


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Homo sapiens)


name: L-arogenate + NADP(+) <=> CO2 + L-tyrosine + NADPH


name: (R)-mandelamide + H2O => (R)-mandelate + NH4(+)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Drosophila melanogaster)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: 13-deoxydaunorubicin + H(+) + NADPH + O2 => 13-dihydrodaunorubicin + H2O + NADP(+)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Gallus gallus)


name: 3-phenylpropanoate + NAD(+) <=> (E)-cinnamate + H(+) + NADH


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Mus musculus)


name: [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + ATP + H(+) => [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + diphosphate


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Mus musculus)


name: (3R)-hydroxyhexadecanedioyl-CoA + NAD(+) <=> 3-oxohexadecanedioyl-CoA + H(+) + NADH


name: NH4(+) + xanthine => H(+) + H2O + isoguanine


name: FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Rattus norvegicus)


name: GSTK1 dimer transfers GS from GSH to CDNB (Sus scrofa)


name: Monoubiquitinated PTEN translocates to the nucleus (Sus scrofa)


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Drosophila melanogaster)


name: Extension of pseudopodia by myosin-X in a PI3K dependent manner (Bos taurus)


name: mTORC1 binds RHEB:GTP (Saccharomyces cerevisiae)


name: hydrogencarbonate(in) + Na(+)(in) => hydrogencarbonate(out) + Na(+)(out)


name: Proteasome mediated degradation of COP1 (Sus scrofa)


name: glycoursodeoxycholate + NADP(+) = 7-oxoglycolithocholate + H(+) + NADPH


name: Phosphorylation of ITAM motifs in CD3 complexes (Rattus norvegicus)


name: Budding of hRSV A virions from infected cell (Homo sapiens)


name: α1-antagonists bind ADRA1A,B,D (Canis familiaris)


name: all-trans-retinol--[retinol-binding protein] + NAD(+) <=> all-trans-retinal--[retinol-binding protein] + H(+) + NADH


name: alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + H(+) + UDP


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Caenorhabditis elegans)


name: dihydrosanguinarine + H(+) + O2 <=> H2O2 + sanguinarine


name: SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Homo sapiens)


name: DAG is acylated to TAG by DGAT1/2 (Dictyostelium discoideum)


name: Dissociation of Phospho-Nlp from the centrosome (Mus musculus)


name: H2O + tridecanoylglycerol <=> 2,3-didecanoyl-sn-glycerol + decanoate + H(+)


name: MMP14 (MT1-MMP) binds TIMP2 (Drosophila melanogaster)


name: Activation of cytosolic AMPK by phosphorylation (Rattus norvegicus)


name: acetyl-CoA + beta-D-glucose => 6-O-acetyl-beta-D-glucose + CoA


name: PIP3 recruits PDK1 and AKT to the membrane (Danio rerio)


name: (2E,6E)-farnesyl diphosphate + 2 H2O => 7-epi-ent-eudesmane-5,11-diol + diphosphate


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + H2O => 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + NH4(+)


name: 3-dehydro-L-erythronate + ATP => 3-dehydro-4-O-phospho-L-erythronate + ADP + H(+)


name: Metabotropic glutamate receptors bind glutamate (Sus scrofa)


name: TFIIH-class transcription factor complex binding


name: PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Canis familiaris)


name: a 6-acetyl-beta-D-galactoside + CoA => a beta-D-galactoside + acetyl-CoA


name: MMACHC:cob(II)alamin binds MMADHC (Homo sapiens)


name: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-apiose <=> 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + H(+) + UDP


name: (+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + N(6)-acetyl-L-lysine => 6-acetamido-2-oxohexanoate + L-glutamate


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O <=> an N-acylsphing-4-enine + D-galactose


name: PRC1 SUMOylates CTBP1 with SUMO1 (Gallus gallus)


name: TP53 stimulates BTG2 expression (Homo sapiens)


name: eIF5B:GTP is hydrolyzed and released (Dictyostelium discoideum)


name: glycine + L-cysteine => H2O + L-cysteinylglycine


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Bos taurus)


name: D-galactosamine 6-phosphate + H2O => D-tagatopyranose 1-phosphate + NH4(+)


name: Phosphorylation of PLCgamma by PDGFR (Gallus gallus)


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Canis familiaris)


name: N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Rattus norvegicus)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Homo sapiens)


name: Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + CO2 + S-adenosyl-L-homocysteine


name: CIDEA:CIDEC binds lipid droplets (Homo sapiens)


name: NTHL1 glycosylase mediated recognition and binding of formamidopyrimidine (FapyA) (Homo sapiens)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Bos taurus)


name: Addition of nucleotides leads to transcript elongation (Drosophila melanogaster)


name: PDSS1,2 ligates FPP to IPPP (Plasmodium falciparum)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate <=> (E,R)-alpha-bisabolene + diphosphate


name: ATP(in) + CoA(in) + dodecanoate(out) + H(+)(out) => AMP(in) + diphosphate(in) + dodecanoyl-CoA(in) + H(+)(in)


name: HIPK2 phosphorylates TP53 (Homo sapiens)


name: p-S115 MAPKAPK5 translocates to the cytosol (Sus scrofa)


name: MMACHC:cob(II)alamin binds MMADHC (Xenopus tropicalis)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Rattus norvegicus)


name: L-cystine(out) + L-glutamate(in) = L-cystine(in) + L-glutamate(out)


name: IL3RB is phosphorylated on Ser-585 (Mus musculus)


name: Localization of CBL:GRB2 to the membrane (Homo sapiens)


name: SMURF1/2 ubiquitinates PRICKLE1 (Canis familiaris)


name: MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants (Homo sapiens)


name: 1-methylimidazole-4-acetaldehyde + H2O2 + NH4(+) => H2O + N(tau)-methylhistamine + O2


name: NOX3 complex:RAC1:GTP generates superoxide from oxygen (Homo sapiens)


name: S-adenosyl-L-methionine + trans-resveratrol = 3-methoxy-4',5-dihydroxy-trans-stilbene + H(+) + S-adenosyl-L-homocysteine


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Xenopus tropicalis)


name: ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate


name: 2-oxobutanoate + N(omega),N(omega)-dimethyl-L-arginine = (2S)-2-aminobutanoate + 5-(3,3-dimethylguanidino)-2-oxopentanoate


name: H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine


name: Receptors CCR3, 4 and 5 bind CCL5 ligand (Homo sapiens)


name: LTA4 translocates from neutrophil cytosol to platelet cytosol (Homo sapiens)


name: holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Sus scrofa)


name: CoA + H(+) + piperine => (E,E)-piperoyl-CoA + piperidine


name: all-trans-retinoate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-retinal + O2 + reduced [NADPH--hemoprotein reductase]


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Sus scrofa)


name: Activation of RAS by p-KIT bound SOS1 (Drosophila melanogaster)


name: Serine phosphorylation of STATs (Homo sapiens)


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Rattus norvegicus)


name: 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: Proteasome mediated degradation of COP1 (Homo sapiens)


name: Separation of elongating transcript from template (Drosophila melanogaster)


name: all-trans-retinol + hexadecanoyl-CoA => all-trans-retinyl hexadecanoate + CoA


name: H2O + stachyose <=> D-galactose + raffinose


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Canis familiaris)


name: AVP(20-28) binds AVPR2 (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate <=> (E)-2-epi-beta-caryophyllene + diphosphate


name: P4 bind PGR (in the HSP90 chaperone complex) (Mus musculus)


name: UDP-beta-L-arabinopyranose(in) + UMP(out) = UDP-beta-L-arabinopyranose(out) + UMP(in)


name: HDAC6 deacetylates microtubules (Dictyostelium discoideum)


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Rattus norvegicus)


name: Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide => Ni(2+) + pyridinium-3,5-bisthiocarboxylate mononucleotide


name: 4-cresol dehydrogenase (hydroxylating) activity


name: (E)-alk-1-en-1-SO-peroxol <=> (Z)-alkanethial oxide


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Xenopus tropicalis)


name: TRIM33 monoubiquitinates SMAD4 (Canis familiaris)


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: ATP + hydrogencarbonate + propanoyl-CoA => ADP + H(+) + methylmalonyl-CoA + phosphate


name: D-serine(in) + L-glutamine(out) + Na(+)(out) = D-serine(out) + L-glutamine(in) + Na(+)(in)


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Bos taurus)


name: Docking of Mature Histone mRNA complex:TAP at the NPC (Gallus gallus)


name: RAC3 translocates to the endoplasmic reticulum membrane (Sus scrofa)


name: 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin] => cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Dictyostelium discoideum)


name: 2-trans-(+)-abscisate + UDP-alpha-D-glucose <=> beta-D-glucopyranosyl trans-(+)-abscisate + UDP


name: AHRR binds ARNT (Drosophila melanogaster)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O <=> preluffariellolide A


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)


name: Formation of HIF:CBP:p300 complex at promoters (Drosophila melanogaster)


name: Pro-beta-NGF and mature beta-NGF are secreted (Sus scrofa)


name: 1,8-diazacyclotetradecane-2,9-dione + H2O <=> N-(6-aminohexanoyl)-6-aminohexanoate


name: Sequestration of tBID by BCL-2 (Gallus gallus)


name: LGI3 binds ADAM22,23,synatxin1 (Sus scrofa)


name: ATG12 binds ATG7 dimer (Caenorhabditis elegans)


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Bos taurus)


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + tau-cadinol


name: glutathione + prostaglandin A2 <=> prostaglandin A2-S-(R)-glutathione


name: Cyclisation of GTP to precursor Z (Xenopus tropicalis)


name: MARCO:ligand is endocytosed (Homo sapiens)


name: Formation of anchoring fibrils (Mus musculus)


name: PKC-delta translocates to plasma membrane (Sus scrofa)


name: adenosine 5'-phosphosulfate + phosphate => ADP + H(+) + sulfate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA


name: PAQR3 binds inactive RAFs (Homo sapiens)


name: SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)


name: volume-sensitive chloride channel activity


name: P3HB binds 4-Hyp-collagen propeptides (Homo sapiens)


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Dictyostelium discoideum)


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Drosophila melanogaster)


name: Imatinib-resistant KIT mutants do not bind imatinib (Homo sapiens)


name: hexadecanoyl-CoA + L-cysteinyl-[protein] => CoA + S-hexadecanoyl-L-cysteinyl-[protein]


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Caenorhabditis elegans)


name: H(+)(in) + L-arabinose(in) = H(+)(out) + L-arabinose(out)


name: a ganglioside GA2 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GM2 (d18:1(4E)) + CMP + H(+)


name: Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Rattus norvegicus)


name: (2E,4E)-2,4-dichloromuconate + H(+) => 2,4-dichloro-5-oxo-2,5-dihydro-2-furylacetate


name: (R)-carnitine(out) + ATP + H2O = (R)-carnitine(in) + ADP + H(+) + phosphate


name: (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose => (20S)-ginsenoside Rg3 + H(+) + UDP


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Mus musculus)


name: an isogloboside iGb3Cer + H(+) + UDP => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose


name: L-Glutamine transport into neurons (Canis familiaris)


name: (12R)-hydroxy-(9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphocholine = (12R-hydroxy-9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: a tRNA precursor + 2 CTP = a tRNA with a 3' CC end + 2 diphosphate


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Danio rerio)


name: Tyrosine kinases phosphorylate the receptor (Bos taurus)


name: 1,4-diguanidinobutane + H2O => agmatine + urea


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Rattus norvegicus)


name: TP53INP1 and HIPK2 bind TP53 (Sus scrofa)


name: CHD1L is recruited to GG-NER site (Sus scrofa)


name: (E,E)-2,4-hexadien-1-ol + NADP(+) => (E,E)-2,4-hexadienal + H(+) + NADPH


name: LIG1 binds APEX1 and PCNA at SSB (Mus musculus)


name: (Z)-(4-hydroxyphenyl)acetaldehyde oxime => 4-hydroxyphenylacetonitrile + H2O


name: dodecanoyl-AMP + holo-[ACP] = AMP + dodecanoyl-[ACP] + H(+)


name: COX15 transforms heme O to heme A (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: L-proline + NH4(+) => H2O + L-prolinamide


name: hyocholate + UDP-alpha-D-glucuronate => hyocholoyl-24-O-(beta-D-glucuronate) + UDP


name: (S)-2-methyl-3-oxopropanoate + CoA + H2O + NAD(+) => H(+) + hydrogencarbonate + NADH + propanoyl-CoA


name: PLA1A hydrolyses PS to 2-acyl LPS (Canis familiaris)


name: 3-fumarylpyruvate + H2O = fumarate + H(+) + pyruvate


name: N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: Pellino ubiquitinates hp-IRAK1 (Canis familiaris)


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate => (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: Microtubule-independent trafficking of connexons to the plasma membrane (Gallus gallus)


name: 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate => D-mannose 6-phosphate + H2O + phosphoenolpyruvate


name: MLKL binds PDCD6IP and SDCBP (Mus musculus)


name: HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 (Homo sapiens)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2 = 2-dehydro-D-glucose + H2O2 + L-glutamate


name: dATP + 2 H2O => dAMP + 2 H(+) + 2 phosphate


name: 1D-chiro-inositol(out) + 2 Na(+)(out) <=> 1D-chiro-inositol(in) + 2 Na(+)(in)


name: 3-iodo-L-tyrosine + iodide + NADP(+) => 3,5-diiodo-L-tyrosine + H(+) + NADPH


name: P2RY12 binds P2RY12 antagonists (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O <=> (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+)


name: ATP + H2O + methyl beta-D-galactoside(out) = ADP + H(+) + methyl beta-D-galactoside(in) + phosphate


name: p-4Y-SIRPA:CD47 binds GRB2-1 (Homo sapiens)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Schizosaccharomyces pombe)


name: a uridine in tRNA + H(+) + NADH => a 5,6-dihydrouridine in tRNA + NAD(+)


name: AFG3L2 binds mitochondrial matrix proteins (Sus scrofa)


name: ITGA4:ITGB1 binds natalizumab (Xenopus tropicalis)


name: H(+) + NADPH + zymosterone = NADP(+) + zymosterol


name: 3-dehydroshikimate + H2O => 3-dehydroquinate


name: Ubiquitinated Cdc6 is degraded by the proteasome (Mus musculus)


name: ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA (Sus scrofa)


name: D-maltopentaose + O2 <=> D-maltopentaono-1,5-lactone + H2O2


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Rattus norvegicus)


name: 3-hydroxyoctadecanoyl-CoA <=> (2E)-octadecenoyl-CoA + H2O


name: (2E,6E)-farnesyl diphosphate = (1E,4E)-germacrene B + diphosphate


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: MASTL (GWL) phosphorylates ARPP19 (Drosophila melanogaster)


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Plasmodium falciparum)


name: Activated TAK1 leaves endosome membrane (Gallus gallus)


name: Serum albumin binds 2-lysophosphatidylcholine (Sus scrofa)


name: SETD6 methylates RELA in the NFkB complex (Sus scrofa)


name: p-T,Y MAPK dimers translocate to nucleus (Xenopus tropicalis)


name: SLC26A3,6 exchange Cl- for HCO3- (Caenorhabditis elegans)


name: SALMs1-3 bind each other in cis interactions (Caenorhabditis elegans)


name: an N-acylsphing-4-enine 1-phosphoethanolamine + CMP + H(+) => an N-acylsphing-4-enine + CDP-ethanolamine


name: acetate + D-glucosamine 6-phosphate => H2O + N-acetyl-D-glucosamine 6-phosphate


name: H(+) + NADPH + O2 + resorcinol <=> benzene-1,2,4-triol + H2O + NADP(+)


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 3-acyl-sn-glycerol <=> a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: a menaquinol + 2 O2 => a menaquinone + 2 H(+) + 2 superoxide


name: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 3-hydroxy-2-methylpyridine-5-carboxylate + CO2


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Canis familiaris)


name: Endocytosis of TRAM (TICAM2) (Rattus norvegicus)


name: COQ6 hydroxylates DHB (Caenorhabditis elegans)


name: Docking of the Mature intronless derived transcript derived mRNA, TAP and Aly/Ref at the NPC (Homo sapiens)


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Gallus gallus)


name: CYP17A1 17-hydroxylates P4 to 17aHPROG (Xenopus tropicalis)


name: 4-hydroxy-all-trans-beta-carotene + AH2 + O2 <=> 4,4-dihydroxy-all-trans-beta-carotene + A + H2O


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Mus musculus)


name: SMPD1 hydrolyzes SPHM (Xenopus tropicalis)


name: 13-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: dodecanoyl-CoA + O2 => (2E)-dodecenoyl-CoA + H2O2


name: dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid <=> desmethyldescarbamoylnovobiocin + dTDP + H(+)


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) <=> 4-deoxy-6-O-methyl-L-threo-hex-4-enopyranuronate + [(1->4)-alpha-D-galacturonosyl methyl ester](n-1)


name: NBR1 translocates from cytosol to perixosomal membrane (Homo sapiens)


name: prostaglandin E1 => H2O + prostaglandin A1


name: Formation of the closed pre-initiation complex (Bos taurus)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine <=> an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] (Homo sapiens)


name: Alpha-1-Microglobulin is cleaved (Sus scrofa)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)


name: 25(R) DHCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)


name: Activated FGFR3 phosphorylates FRS2 (Rattus norvegicus)


name: PTGS2 dimer oxidises EPA to PGH3 (Canis familiaris)


name: Active G alpha (z) binds RGS proteins (Gallus gallus)


name: 2,4,6-trichloroanisole + S-adenosyl-L-homocysteine => 2,4,6-trichlorophenol + S-adenosyl-L-methionine


name: Alternative endo-mannosidase I route (Drosophila melanogaster)


name: The Immunoglobulin of the BCR binds antigen (Canis familiaris)


name: Phosphorylated STAT1, STAT3 form dimers (Sus scrofa)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Caenorhabditis elegans)


name: deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Bos taurus)


name: acetate + malonyl-CoA => acetyl-CoA + malonate


name: Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 (Mus musculus)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Canis familiaris)


name: (9S,13S,15Z)-12-oxophyto-10-15-dienoate + ATP + CoA <=> (10Z,15Z)-12-oxophytodienoyl-CoA + AMP + diphosphate


name: ATP + L-seryl-[tyrosine-3-monooxygenase] => ADP + H(+) + O-phospho-L-seryl-[tyrosine-3-monooxygenase]


name: 7beta-hydroxycholesterol(in) + ATP + H2O <=> 7beta-hydroxycholesterol(out) + ADP + H(+) + phosphate


name: transmembrane receptor protein tyrosine kinase activator activity


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Schizosaccharomyces pombe)


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Bos taurus)


name: 1-hexadecanoylglycerone 3-phosphate + heptadecan-1-ol => 1-O-heptadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: PEX19:class I PMP binds PEX3 (Sus scrofa)


name: GABA loaded synaptic vesicle Docking and Priming (Caenorhabditis elegans)


name: geranylgeranyl diphosphate <=> diphosphate + elisabethatriene


name: MITF-M dimer binds the DICER1 gene (Homo sapiens)


name: Expression of NOTO in axial mesoderm (Homo sapiens)


name: 1,6-dihydroxyphenazine N(5)-oxide + H2O + NADP(+) => 1,6-dihydroxyphenazine + NADPH + O2


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA => 1-O-alkyl-sn-glycero-3-phosphocholine + an acyl-CoA


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: OCT2 mediates tubular uptake of organic cations in the kidney (Danio rerio)


name: Cleavage of mRNA at the 3'-end (Mus musculus)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Xenopus tropicalis)


name: Cross-linking of FCGRIIA with IgG-coated Ag (Canis familiaris)


name: SEMA4D interacts with Plexin-B1:Met (Mus musculus)


name: 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-[malonate decarboxylase ACP] => diphosphate + holo-[malonate decarboxylase ACP]


name: a sphingomyelin + H2O => an N-acylsphing-4-enine 1-phosphate + choline + H(+)


name: Activated FGFR3 phosphorylates FRS3 (Mus musculus)


name: citrate(out) + maleate(in) <=> citrate(in) + maleate(out)


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Bos taurus)


name: ETA is phosphorylated to PETA by CHK/ETNK (Canis familiaris)


name: H2O + tuberculosinyl diphosphate <=> (13R)-edaxadiene + diphosphate


name: L-tyrosyl-[protein] + NAD(+) = H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein]


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Canis familiaris)


name: DVL1 is ubiquitinated by HECW1 (Drosophila melanogaster)


name: N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: butanoyl-CoA + ethanol = CoA + ethyl butanoate


name: ASIC3 channel blockers bind ASIC3 trimer (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Rattus norvegicus)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + H2O <=> (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + D-glucuronate + H(+)


name: [thioredoxin]-dithiol + prostaglandin H2 <=> [thioredoxin]-disulfide + prostaglandin F2alpha


name: (6E)-8-hydroxygeraniol + NAD(+) = (6E)-8-hydroxygeranial + H(+) + NADH


name: POLB-mediated DNA strand displacement synthesis (Canis familiaris)


name: (20S)-ginsenoside R1 + H2O <=> (20S)-ginsenoside Rg1 + D-xylose


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Saccharomyces cerevisiae)


name: (E)-4-hydroxynon-2-enal + H2O + NADP(+) <=> (E)-4-hydroxynon-2-enoate + 2 H(+) + NADPH


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Mus musculus)


name: TPMT transfers methyl group to 6TIMP, forming 6MeTIMP (Homo sapiens)


name: 1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol + H2O <=> dodecanoate + dodecanoyl-3-beta-D-galactosyl-sn-glycerol + H(+)


name: 2-oxoglutarate + 6-aminohexanoate => 6-oxohexanoate + L-glutamate


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Rattus norvegicus)


name: succinate(out) + urate(in) => succinate(in) + urate(out)


name: a menaquinol + dimethyl sulfoxide => a menaquinone + dimethyl sulfide + H2O


name: IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Homo sapiens)


name: L-seryl-[protein] + tetradecanoyl-CoA => CoA + O-tetradecanoyl-L-seryl-[protein]


name: ALOX5 oxidises 17(S)-HDHA to 7(S)-Hp-17(S)-HDHA (Canis familiaris)


name: 3-alpha(S)-strictosidine + H2O => secologanin + tryptamine


name: UDP-glucose is oxidised to UDP-glucuronate (Rattus norvegicus)


name: [thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide


name: a ganglioside Ac-O-7-GD3(d18:1(4E)) <=> a ganglioside Ac-O-8-GD3(d18:1(4E))


name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Xenopus tropicalis)


name: Acireductone is created (Xenopus tropicalis)


name: H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-ol => 2 H(+) + O2 + pentalenene + 2 reduced [2Fe-2S]-[ferredoxin]


name: complement component C3a receptor activity


name: H(+) + 2 malonyl-CoA + nicotinyl-CoA => 4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one + 2 CO2 + 3 CoA


name: an N-acetyl-alpha-D-glucosaminyl derivative + UDP-alpha-D-galactose <=> a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl derivative + H(+) + UDP


name: PARP1 binds SMAD2/3:SMAD4 heterotrimer (Drosophila melanogaster)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Caenorhabditis elegans)


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Sus scrofa)


name: (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase]


name: L1 and NCAM1 engaged in cis-interaction (Mus musculus)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+)


name: dGTP + methylglyoxal => N(2)-(1-hydroxy-2-oxopropyl)-dGTP


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: G-protein coupled bile acid receptor binds lithocholic acid (Xenopus tropicalis)


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Gallus gallus)


name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Rattus norvegicus)


name: a ganglioside Ac-O-8-GD1a => a ganglioside Ac-O-9-GD1a


name: JAK2 transphosphorylates and is activated in response to Erythropoietin (Homo sapiens)


name: 2-methylbutanamine + H2O + NAD(+) = 2-methylbutanal + H(+) + NADH + NH4(+)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Gallus gallus)


name: (3R)-hydroxyhexadecanedioyl-CoA + NAD(+) = 3-oxohexadecanedioyl-CoA + H(+) + NADH


name: NIPAs transport Mg2+ from extracellular region to cytosol (Danio rerio)


name: MAF1 translocates to the nucleus (Bos taurus)


name: acetyl-CoA + 2 AH2 + 9 H(+) + malate + 6 malonyl-CoA + 5 NADPH + 2 S-adenosyl-L-methionine <=> 2 A + 6 CO2 + 7 CoA + 6 H2O + 5 NADP(+) + 2 S-adenosyl-L-homocysteine + trihazone A


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Bos taurus)


name: SARS-CoV-2 N protein binds STAT1, STAT2 (Homo sapiens)


name: ATP + holo-[peptidyl-carrier protein] + L-tryptophan => AMP + diphosphate + L-tryptophyl-[peptidyl-carrier protein]


name: (2E,11Z)-octadecadienoyl-CoA + H(+) + NADPH => (11Z)-octadecenoyl-CoA + NADP(+)


name: Caspase mediated cleavage of vimentin at IDVD (259) (Gallus gallus)


name: 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O = 4-oxohex-2-enedioate + H(+)


name: ANKLE2 binds VRK1,(VRK2) (Rattus norvegicus)


name: FAHD1 dimer hydrolyses OA to PYR (Sus scrofa)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Bos taurus)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Rattus norvegicus)


name: daunorubicin + H(+) + NADPH + O2 = doxorubicin + H2O + NADP(+)


name: Resynthesis of excised residue by POLB (Sus scrofa)


name: TTR:RBP:atROL binds to STRA6 receptor (Xenopus tropicalis)


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Canis familiaris)


name: FOXO3,FOXO4,(FOXO1) bind GADD45A gene promoter (Homo sapiens)


name: Recruitment of VAV1 to p-6Y-SYK (Bos taurus)


name: alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-3,6-dideoxy-alpha-D-mannose <=> alpha-D-Tyv-(1->3)-alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: Parathyroid hormone receptor can bind parathyroid hormone (Canis familiaris)


name: aldehydo-D-glucuronate(in) + H(+)(in) => aldehydo-D-glucuronate(out) + H(+)(out)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Canis familiaris)


name: Basigin binds MCT1, MCT3 and MCT4 (Gallus gallus)


name: 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + ATP + L-cysteine = 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + H(+)


name: SLC6A6-mediated uptake of taurine and beta-alanine (Rattus norvegicus)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Danio rerio)


name: AMP + diphosphate + H(+) + staphyloferrin A => ATP + citrate + N(5)-[(S)-citryl]-D-ornithine


name: H2O + N(5)-hydroxy-L-ornithine + NAD(+) => L-ornithine + NADH + O2


name: 11-oxo-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] <=> 30-hydroxy-11-oxo-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Bos taurus)


name: 6-(hexadecan-2-yl)-4-hydroxy-pyran-2-one + 2 CO2 + 3 CoA => 2-methylhexadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: secretion of WNT ligands (Rattus norvegicus)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Rattus norvegicus)


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Homo sapiens)


name: 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a = chlorophyllide a + H2O


name: Dissociation of CaM and CAMK2 autophosphorylation (Canis familiaris)


name: H2O + N-hexadecanoyl-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + hexadecanoate


name: 7-oxocholesterol + H(+) + NADPH <=> 7beta-hydroxycholesterol + NADP(+)


name: HGSNAT oligomer acetylates Heparan chain(1) (Mus musculus)


name: IL21 receptor JAK phosphorylation (Mus musculus)


name: p-S303,307-HSF1 binds YWHAE (14-3-3) (Drosophila melanogaster)


name: 3-oxosphinganine + docosanoyl-CoA <=> CoA + H(+) + N-docosanoyl-3-ketodihydrosphingosine


name: ADRB2 in ADRB2:GRK complex is phosphorylated (Sus scrofa)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Drosophila melanogaster)


name: isopentenyl diphosphate + neryl diphosphate <=> (2Z,6Z)-farnesyl diphosphate + diphosphate


name: L-leucyl-tRNA(Leu) + L-phenylalanyl-tRNA(Phe) <=> cyclo(L-phenylalanyl-L-leucyl) + H(+) + tRNA(Leu) + tRNA(Phe)


name: GTP-binding activates eEF2 (Canis familiaris)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Dictyostelium discoideum)


name: (S)-lactate + 2 H(+) + NADH => (S)-lactaldehyde + H2O + NAD(+)


name: indolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] = 3-hydroxyindolin-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: C5 binds C5 inhibitors (Canis familiaris)


name: p-T182 MAPKAPK5 phosphorylates FOXO3 (Bos taurus)


name: SHC1 in the RET complex is phosphorylated (Bos taurus)


name: Beta-catenin migrates to the nucleus (Bos taurus)


name: Luteinizing hormone is a heterodimer (Rattus norvegicus)


name: glycyl-L-glutamate + H2O = glycine + L-glutamate


name: H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline <=> 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n)


name: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O => 2 beta-L-arabinofuranose


name: NTPDase7 hydrolyzes nucleoside triphosphates (Homo sapiens)


name: β-blockers bind ADRB1,2,3 (Gallus gallus)


name: Secretion of transmembrane collagens (Xenopus tropicalis)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Rattus norvegicus)


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Canis familiaris)


name: MMP2,9 cleave EPHB (Drosophila melanogaster)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Drosophila melanogaster)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Xenopus tropicalis)


name: (15S)-hydroperoxy-(11Z,13E)-eicosadienoate => (11Z,14Z)-eicosadienoate + O2


name: 3,6-anhydro-alpha-L-galactopyranose + H2O + NADP(+) => 3,6-anhydro-L-galactonate + 2 H(+) + NADPH


name: aldehyde dehydrogenase (FAD-independent) activity


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Schizosaccharomyces pombe)


name: Viral dsRNA:TLR3:TRIF complex recruits RIP1 (Homo sapiens)


name: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate


name: (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O => bisdemethoxycurcumin + CO2 + 2 CoA


name: ADP + beta-L-fucose 1-phosphate + H(+) => ATP + L-fucose


name: a D-5-monosubstituted hydantoin <=> a L-5-monosubstituted hydantoin


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Caenorhabditis elegans)


name: Phosphorylation of IRS (Rattus norvegicus)


name: Gi,Go Heterotrimeric G-protein complex dissociates (Danio rerio)


name: ATP + glutathione(in) + glycoursodeoxycholate(in) + H2O => ADP + glutathione(out) + glycoursodeoxycholate(out) + H(+) + phosphate


name: VEGFA-165 dimer binds VEGFA inhibitors (Sus scrofa)


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)


name: acetyl-CoA + N-acetylneuraminate => CoA + N-acetyl-7-O-acetylneuraminate


name: a 3'-end 3'-phospho-ribonucleotide-RNA + H(+) + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] => a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + L-histidyl-[RNA ligase]


name: 2-hydroxy-5-methyl-1-naphthoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2,7-dihydroxy-5-methyl-1-naphthoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Caenorhabditis elegans)


name: Clusterin binds C5b-C7, C8, C9 (Mus musculus)


name: GRK1,4,7 phosphorylate MII to p-MII (Canis familiaris)


name: Activated FGFR2:p-FRS bind to PPTN11 (Mus musculus)


name: HSPG2 (perlecan) binds alpha-dystroglycan (Caenorhabditis elegans)


name: PP2A-B56 dephosphorylates centromeric cohesin (Xenopus tropicalis)


name: Clathrin internalises EPH:EFN complexes (Homo sapiens)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)


name: RUNX3 translocates to the nucleus (Caenorhabditis elegans)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Canis familiaris)


name: formononetin + O2 + reduced [NADPH--hemoprotein reductase] <=> calycosin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Sus scrofa)


name: L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: Mitochondrial FPGS-1 transforms THF to THFPG (Schizosaccharomyces pombe)


name: SENP1,2,5 proteolytically process SUMO2 (Mus musculus)


name: pre-mRNA intronic pyrimidine-rich binding


name: a 5'-end NTP-ribonucleotide-RNA + H2O = a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + diphosphate + H(+)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Caenorhabditis elegans)


name: a dolichyl N-acetyl-alpha-D-glucosaminyl phosphate + UDP => a dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Rattus norvegicus)


name: WWTR1 (TAZ) binds TEAD (Caenorhabditis elegans)


name: Activation of Rap1 by cytosolic GEFs (Bos taurus)


name: LC3:ATG7 dimer binds ATG3 (Rattus norvegicus)


name: p-PKR dimer phosphorylates SPHK1 (Rattus norvegicus)


name: D-glyceraldehyde 3-phosphate + H(+) + pyruvate <=> 1-deoxy-D-xylulose 5-phosphate + CO2


name: Substrate:LAMP2a binds HSP90 (Homo sapiens)


name: Phosphorylated Cdc6 is exported from the nucleus (Homo sapiens)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Xenopus tropicalis)


name: 4-aminobutanoate(in) + H(+)(in) => 4-aminobutanoate(out) + H(+)(out)


name: PTHP is reduced to BH4 by sepiapterin reductase (SPR) (Dictyostelium discoideum)


name: kaempferol + S-adenosyl-L-methionine = 3-O-methylkaempferol + H(+) + S-adenosyl-L-homocysteine


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Gallus gallus)


name: ADP + ATP + H(+) <=> P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate


name: NADPH + O2 + questin => demethylsulochrin + NADP(+)


name: MMACHC decyanates CNCbl (Rattus norvegicus)


name: (indol-3-yl)acetate + succinyl-CoA => (indol-3-yl)acetyl-CoA + succinate


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Saccharomyces cerevisiae)


name: PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Drosophila melanogaster)


name: D-ribose + H2O + NADP(+) <=> D-ribonate + 2 H(+) + NADPH


name: 1-octadecanoyl-sn-glycero-3-phosphoserine + H2O => H(+) + octadecanoate + sn-glycero-3-phospho-L-serine


name: (2Z,6Z)-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate


name: Activated MAPKs phosphorylate MAP2K1 (Bos taurus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Danio rerio)


name: 5-methylorsellinate + O2 + reduced [NADPH--hemoprotein reductase] <=> 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GDP-beta-L-colitose + NADP(+) = GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + H(+) + NADPH


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Rattus norvegicus)


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Sus scrofa)


name: PPP1R3C binds to glycogen:GYG2:GYS2 (Canis familiaris)


name: 8-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 8,20-dihydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-hydroxylimonen-2-one + H(+) + NADPH + O2 <=> 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: 2-oxoglutarate + L-lysine + O2 => (3S)-3-hydroxy-L-lysine + CO2 + succinate


name: GTP + UTP <=> 3',3'-cGMP-UMP + 2 diphosphate


name: G-protein alpha subunit is inactivated (Homo sapiens)


name: 16,17-epoxy-(7Z,10Z,13Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: cyanidin 3,5-diglucoside glucosidase activity


name: L-threonyl-[protein] + UDP-alpha-D-glucose = 3-O-(alpha-D-glucosyl)-L-threonyl-[protein] + H(+) + UDP


name: 3-oxohexanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxyhexanoyl-[ACP] + NADP(+)


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Bos taurus)


name: PHF20 binds TP53 dimethylated on K370 and K382 (Mus musculus)


name: a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + an aliphatic (Z)-desulfo-glucosinolate


name: AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate = A + semiviriditoxin


name: AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Homo sapiens)


name: Bacterial GUSB hydrolyses BDG to BIL (Homo sapiens)


name: (R)-S-lactoylglutathione => glutathione + methylglyoxal


name: PIAS4 SUMOylates PPARA with SUMO1 (Mus musculus)


name: (14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate = (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O


name: benzylamine + H2O + NAD(+) = benzaldehyde + H(+) + NADH + NH4(+)


name: 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate = 7,8-dihydroneopterin 3'-phosphate + H2O


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Canis familiaris)


name: PE is converted to PS by PTDSS2 (Canis familiaris)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Mus musculus)


name: monoatomic anion:sodium symporter activity


name: AH2 + echinenone + O2 = 4'-hydroxyechinenone + A + H2O


name: WNTs are secreted in exosomes (Homo sapiens)


name: (9Z)-octadecenoate + L-asparagine => H2O + N-(9Z-octadecenoyl)-L-asparagine


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Rattus norvegicus)


name: (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA => (22E)-3-oxochola-4,22-dien-24-oyl-CoA + H2O


name: collagen binding involved in cell-matrix adhesion


name: guanosine(26) in tRNA + 2 S-adenosyl-L-methionine <=> 2 H(+) + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Gallus gallus)


name: TAK1 is activated within the TAK1 complex (Canis familiaris)


name: a 5'-end ribonucleotide-tRNA(His) + ATP + GTP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)


name: PIAS4 SUMOylates VHL with SUMO1 (Danio rerio)


name: Activated FGFR1 binds FLRT1,2,3 (Xenopus tropicalis)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Caenorhabditis elegans)


name: Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA (Caenorhabditis elegans)


name: choline + H(+) + NADH + O2 = glycolaldehyde + H2O + NAD(+) + trimethylamine


name: decanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] <=> CoA + H(+) + N(6)-decanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Plasmodium falciparum)


name: dodecanoyl-CoA + NADP(+) => (2E)-dodecenoyl-CoA + H(+) + NADPH


name: epitestosterone 17-sulfate(out) + 2 Na(+)(out) = epitestosterone 17-sulfate(in) + 2 Na(+)(in)


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Caenorhabditis elegans)


name: 2 CO2 + 4 H2O + heme b => Fe-coproporphyrin III + 2 H(+) + 2 H2O2


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Drosophila melanogaster)


name: LYZ binds bacterial peptidoglycan (Gallus gallus)


name: FDPS dimer transfers IPPP to DMAPP (Rattus norvegicus)


name: a 1-acyl-sn-glycerol + ATP <=> a 1-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: GSDME (1-270) binds cardiolipin (Canis familiaris)


name: Phosphorylation of PKC-theta (Bos taurus)


name: STARD7 transports Q10 to plasma membrane (Caenorhabditis elegans)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Rattus norvegicus)


name: 2xTPK1:Mg2+ phosphorylates THMN (Sus scrofa)


name: 2-oxoglutarate + an alkane-alpha,omega-diamine <=> an omega-aminoaldehyde + L-glutamate


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA => an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + holo-[ACP]


name: a 1-acyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) => a 1-acyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: Translocation of STAT1 dimer to nucleus (Bos taurus)


name: a 1-O-alkyl-2-acetyl-sn-glycerol + H2O = 1-O-alkyl-sn-glycerol + acetate + H(+)


name: IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel (Homo sapiens)


name: Caspase-mediated cleavage of plectin-1 (Mus musculus)


name: 4-chlorocatechol + O2 = 3-chloro-cis,cis-muconate + 2 H(+)


name: ATP + beta-D-galactose(out) + H2O => ADP + beta-D-galactose(in) + H(+) + phosphate


name: 5-fluorocytidine + ATP => 5-fluorocytidine 5'-phosphate + ADP + H(+)


name: 4 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) => 4 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: S-adenosyl-L-methionine + uridine(747) in 23S rRNA <=> 5-methyluridine(747) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: L-valine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-valine + oxidized [NADPH--hemoprotein reductase]


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Danio rerio)


name: L-serine + succinyl-CoA = CoA + O-succinyl-L-serine


name: ATP + C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + H2O = AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + diphosphate + H(+) + phosphate


name: diphosphoinositol pentakisphosphate kinase activity


name: ADAMTS13 cleaves VWF variant multimer (Homo sapiens)


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Caenorhabditis elegans)


name: [[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2 reduced [2Fe-2S]-[ferredoxin]


name: [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose = [alpha-D-GalNAc-(1->4)]2-[beta-D-Glc-(1->3)]-[alpha-D-GalNAc-(1->4)]2-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + H(+) + UDP


name: 4-phospho-D-erythronate + NAD(+) => CO2 + dihydroxyacetone phosphate + NADH


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Saccharomyces cerevisiae)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Bos taurus)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Xenopus tropicalis)


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Canis familiaris)


name: ATP + L-glutamate + L-glutamyl-[tubulin] = ADP + gamma-L-glutamyl-L-glutamyl-[tubulin] + H(+) + phosphate


name: (+)-guaia-6,9-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: LIG3:XRCC1 and PNKP bind NEIL1,NEIL2:POLB:SSB(3'Pi)-gap-dsDNA (Canis familiaris)


name: MRN bound to shortened telomeres activates ATM (Saccharomyces cerevisiae)


name: Binding of gp120 of ENV oligomer to the host CD4 (Homo sapiens)


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 1beta-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA => 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: Translocation of ERBB4s80 to the nucleus (Danio rerio)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Bos taurus)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Caenorhabditis elegans)


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Saccharomyces cerevisiae)


name: H(+) + NADPH + sepiapterin => L-threo-7,8-dihydrobiopterin + NADP(+)


name: HSP70 binds to HSP40:nascent protein (Bos taurus)


name: GTP + 4 H2O <=> 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate


name: GEF dissociates from DRheb-GTP (Drosophila melanogaster)


name: PDE12 cleaves 2'-5' oligoadenylates  (Sus scrofa)


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) => 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: estrone 3-sulfate + H2O <=> estrone + H(+) + sulfate


name: NPAS4 gene transcription is repressed by KCNIP3 (Homo sapiens)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Danio rerio)


name: (E)-4-hydroxynon-2-enoate + H(+) + H2O2 => (E)-4-hydroxynon-2-enal + H2O + O2


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Gallus gallus)


name: APRT catalyzes the conversion of adenine to AMP (Schizosaccharomyces pombe)


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Danio rerio)


name: L-proline + NAD(+) => 1-pyrroline-5-carboxylate + 2 H(+) + NADH


name: NOX2 generates superoxide anion from oxygen (Xenopus tropicalis)


name: 4-carboxy-3-methylbut-(2E)-enoyl-[ACP] + H(+) => 3-methylbut-(2E)-enoyl-[ACP] + CO2


name: NADP(+) + reduced coenzyme F420-(gamma-L-Glu)(n) = 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Xenopus tropicalis)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Homo sapiens)


name: C2CD3 binds the mother centriole (Homo sapiens)


name: PI3 binds the bacterial surface (Canis familiaris)


name: CBL autoubiquitinates (Rattus norvegicus)


name: 16beta,17beta-estriol + UDP-alpha-D-glucuronate = 16beta,17beta-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: Recognition and Binding of Core Promoter Elements by TFIID (Caenorhabditis elegans)


name: Phosphorylation of MEK7 by MEKK1 (Canis familiaris)


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Mus musculus)


name: carboxyspermidine + H(+) <=> CO2 + spermidine


name: H(+) + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + NADPH + O2 => 2 H2O + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADP(+)


name: PTPRZ dephosphorylates ligand-bound ALK dimers (Gallus gallus)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Homo sapiens)


name: GSTK1 dimer transfers GS from GSH to CDNB (Danio rerio)


name: 3-diazoavenalumate + AMP + diphosphate + H2O => 3-aminoavenalumate + ATP + H(+) + nitrite


name: 3-hydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine <=> 3-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Homo sapiens)


name: methanesulfonate + NADH + O2 = formaldehyde + H2O + NAD(+) + sulfite


name: Proteolytic degradation of ubiquitinated-Cdc25A (Schizosaccharomyces pombe)


name: ACER3 hydrolyzes phytoceramide (Dictyostelium discoideum)


name: ER calcium channels open in response to activated PKA (Bos taurus)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Rattus norvegicus)


name: PEX19 binds class I peroxisomal membrane proteins (Rattus norvegicus)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)


name: STAB1:ligand is endocytosed (Danio rerio)


name: (3R)-1,4-thiomorpholine-3-carboxylate + NADP(+) <=> 3,4-dehydrothiomorpholine-3-carboxylate + 2 H(+) + NADPH


name: p-BMAL1:p-CLOCK,NPAS2 binds CCRN4L (NOCTURNIN) gene (Homo sapiens)


name: SARDH:FAD oxidatively demethylates SARC to Gly (Bos taurus)


name: H2O + L-alanyl-L-threonine <=> L-alanine + L-threonine


name: (2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (1R)-(2-amino-1-hydroxyethyl)phosphonate + CO2 + succinate


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Xenopus tropicalis)


name: CO binds to Cytochrome c oxidase (Sus scrofa)


name: deacetoxyvindoline + H(+) + S-adenosyl-L-homocysteine => (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Homo sapiens)


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Bos taurus)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Schizosaccharomyces pombe)


name: rifampicin para-naphthoquinone carboxamide => rifampicin ortho-naphthoquinone carboxamide


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Caenorhabditis elegans)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Danio rerio)


name: (9Z)-octadecenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine => 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA


name: ent-kaur-16-en-19-al + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = ent-kaur-16-en-19-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: TCN1 binds correnoids in the circulation (Sus scrofa)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Bos taurus)


name: MITF-M-dependent BCL2A1 gene expression (Homo sapiens)


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Mus musculus)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-2,3-cyclic phosphate + ethanolamine


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + ADP + H(+)


name: 32-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase] => 32-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 5-methylaminomethyl-S-(2E)-geranyl-thiouridine(34) in tRNA + H(+) + selenophosphate <=> (2E)-thiogeraniol + 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA


name: (E)-sinapate + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-sinapate + H(+) + UDP


name: (2E)-dodecenedioyl-CoA + H2O2 => dodecanedioyl-CoA + O2


name: Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Sus scrofa)


name: GIP receptor binds gastric inhibitory peptide (Xenopus tropicalis)


name: PTPN11 binds p-7Y-RUNX1 (Canis familiaris)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Mus musculus)


name: 2-oxoglutarate + D-alanine <=> D-glutamate + pyruvate


name: 2-(prostaglandin E2)-sn-glycero-3-phosphocholine + H2O <=> H(+) + prostaglandin E2 + sn-glycerol 3-phosphocholine


name: dihydroprecondylocarpine acetate + NADPH = (+)-vincadifformine + acetate + NADP(+)


name: ESCRT Disassembly (Saccharomyces cerevisiae)


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Saccharomyces cerevisiae)


name: 2xENPP1 hydrolyzes FAD to FMN (Saccharomyces cerevisiae)


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Mus musculus)


name: Necl-1:Nectin-1 trans heterodimer interaction (Mus musculus)


name: trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Mus musculus)


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Canis familiaris)


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Xenopus tropicalis)


name: diphosphate + sclareol => 8-hydroxycopalyl diphosphate + H2O


name: Delta(2)-thiazoline-2-carboxylate + 2 H(+) + NADPH => L-thiazolidine-2-carboxylate + NADP(+)


name: formaldehyde + H2O + NAD(+) + sulfite => methanesulfonate + NADH + O2


name: 2-furoate + 2 H(+) + NADPH => furfural + H2O + NADP(+)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Canis familiaris)


name: 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + protochlorophyllide b => 5 H(+) + 2 O2 + protochlorophyllide a + 4 reduced [2Fe-2S]-[ferredoxin]


name: AKR1B1 reduces Glc to D-sorbitol (Drosophila melanogaster)


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Canis familiaris)


name: p-Y-STATs dimerize (Drosophila melanogaster)


name: mTORC1 binds RHEB:GTP (Caenorhabditis elegans)


name: phosphate + pyridoxamine <=> H2O + pyridoxamine 5'-phosphate


name: 10-deoxymethymycin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + methymycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Bos taurus)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) (Drosophila melanogaster)


name: SOS binds Grb2 bound to pFAK:NCAM1 (Bos taurus)


name: sorafenib-resistant FLT3 mutants don't bind sorafenib (Homo sapiens)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Schizosaccharomyces pombe)


name: Dissociation of RAS:RAF complex (Canis familiaris)


name: acetyl-CoA + N,N,N-trimethylglycyl-CoA => 3-dehydrocarnityl-CoA + CoA


name: AMP(in) + NAD(+)(out) = AMP(out) + NAD(+)(in)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Homo sapiens)


name: Production of AA by iPLA2 upon FCGR activation (Rattus norvegicus)


name: (3R)-hydroxyhexadecanoyl-[ACP] = (2E)-hexadecenoyl-[ACP] + H2O


name: N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Rattus norvegicus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = (-)-astellatene + diphosphate


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Dictyostelium discoideum)


name: asperaculane G + O2 + reduced [NADPH--hemoprotein reductase] = aculene D + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1)


name: MTMR4 dephosphorylates SMAD2/3 (Drosophila melanogaster)


name: CREB3L3 translocates from the cytosol to the nucleus (Caenorhabditis elegans)


name: (2E)-geraniol + acetyl-CoA => (2E)-geranyl acetate + CoA


name: PDPK1 binds PIP2 (Saccharomyces cerevisiae)


name: (E)-4-coumaroyl alcohol + A => (E)-4-coumaraldehyde + AH2


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Mus musculus)


name: (R)-4'-phosphopantetheine + CO2 => H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine


name: TP53 stimulates and ZNF420 inhibits TP53AIP1 expression (Homo sapiens)


name: (R)-carnitine + ATP + CoA => (R)-carnitinyl-CoA + AMP + diphosphate


name: 4-nitrobenzyl alcohol + NADP(+) => 4-nitrobenzaldehyde + H(+) + NADPH


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+) => 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + NADPH


name: NT5E:Zn2+ hydrolyses NAD+ (Mus musculus)


name: Receptors CCR1, 2 and 8 bind CCL16 ligand (Bos taurus)


name: GLI3R translocates to the nucleus (Canis familiaris)


name: TXLNA (IL14) binds syntaxin1A (Sus scrofa)


name: Caspase-8 activates BID by cleavage (Danio rerio)


name: 2-methylbutanoyl-CoA + H2O = 2-methylbutanoate + CoA + H(+)


name: an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (4R,8Z)-4-hydroxysphing-8-enine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Bos taurus)


name: 4-nitroquinoline N-oxide + 2 H(+) + 2 NADH => 4-(hydroxyamino)quinoline N-oxide + H2O + 2 NAD(+)


name: IRAK1 phosphorylates Pellino (Rattus norvegicus)


name: aluminum ion transmembrane transporter activity


name: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH


name: Exocytosis of azurophil granule membrane proteins (Plasmodium falciparum)


name: chlorothalonil + H2O = 4-hydroxychlorothalonil + chloride + 2 H(+)


name: Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Gallus gallus)


name: dUMP + formaldehyde + H(+) + NADPH <=> dTMP + H2O + NADP(+)


name: H(+) + L-methionyl(44)-[F-actin] + NADPH + O2 <=> H2O + L-methionyl(44)-(R)-S-oxide-[F-actin] + NADP(+)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Gallus gallus)


name: IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Rattus norvegicus)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + scopoletin => 6-methoxycoumarin + O2 + reduced [NADPH--hemoprotein reductase]


name: DOCK180:ELMO binds CRK (Canis familiaris)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Mus musculus)


name: PNPLA4 hydrolyzes retinyl palmitate (Canis familiaris)


name: TFAP2B homodimer binds YEATS4 (Mus musculus)


name: TBK1 is phosphorylated within the activated TLR4 complex (Gallus gallus)


name: apoTF:TFRC dimer translocates from endosome membrane to plasma membrane (Rattus norvegicus)


name: 5-hydroxy-alpha-gurjunene + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Sus scrofa)


name: MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Sus scrofa)


name: a monoacyl-sn-glycero-3-phosphoethanolamine + CoA => an acyl-CoA + sn-glycero-3-phosphoethanolamine


name: Cation influx mediated by TRPC3/6/7 (Rattus norvegicus)


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Canis familiaris)


name: Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)


name: [HPr protein]-L-serine + diphosphate => [HPr protein]-O-phospho-L-serine + H(+) + phosphate


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Gallus gallus)


name: ATP + L-glutamate + tRNA(Glu) => AMP + diphosphate + L-glutamyl-tRNA(Gln)


name: a carotenoid psi-end group <=> a carotenoid epsilon-end group


name: 2-oxoglutarate + nonyl sufate + O2 => CO2 + H(+) + nonanal + succinate + sulfate


name: acetyl-CoA + holo-[ACP] => acetyl-[ACP] + CoA


name: P4HB mediates disulfide bond formation in Proinsulin (Gallus gallus)


name: nsp16 acts as a cap 2'-O-methyltransferase to modify SARS-CoV-1 gRNA (plus strand) (Homo sapiens)


name: p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Plasmodium falciparum)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Canis familiaris)


name: 3,4-dichloroaniline + malonyl-CoA = CoA + N-(3,4-dichlorophenyl)malonamate


name: cGMP dissociates from CNG channels (Canis familiaris)


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Sus scrofa)


name: Association of Cyclin A with the APC/C (Homo sapiens)


name: 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate => 2 5-dehydro-4-deoxy-D-glucuronate


name: p-5Y-RET complexes bind GRB2 (Xenopus tropicalis)


name: glycyl-L-histidine + H2O => glycine + L-histidine


name: D-tyrosyl-tRNA(Tyr) + H2O <=> D-tyrosine + tRNA(Tyr)


name: (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carbonyl-CoA + H(+) + NADPH => (4R,5R)-4,5-dihydroxycyclohex-2-ene-1-carbonyl-CoA + NADP(+)


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Sus scrofa)


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Mus musculus)


name: ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine => (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine


name: [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylsphinganine => a 1,2-diacyl-sn-glycerol + an N-acylsphinganine-1-phosphocholine


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Caenorhabditis elegans)


name: Association of procollagen type X (Rattus norvegicus)


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate <=> D-glyceraldehyde 3-phosphate + pyruvate


name: H(+) + L-methionyl-[F-actin] + NADPH + O2 => H2O + L-methionyl-(R)-S-oxide-[F-actin] + NADP(+)


name: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + 2-oxoglutarate + O2 = 4-O-deacetyl-16-O-demethylvindoline + CO2 + succinate


name: CO2 + H(+) + pentanal + succinate + sulfate => 2-oxoglutarate + O2 + pentyl sulfate


name: PAKs phosphorylate MLC (Drosophila melanogaster)


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Caenorhabditis elegans)


name: D-glucuronate + H(+) + oroxylin A => H2O + oroxylin A 7-O-beta-D-glucuronate


name: P4HB binds Collagen chains (Danio rerio)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Sus scrofa)


name: H2O + L-glutamate + NADP(+) <=> 2-oxoglutarate + H(+) + NADPH + NH4(+)


name: H2O + N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine = (9Z,12Z)-octadecadienoate + H(+) + N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine


name: malvidin + UDP-alpha-D-glucose => malvidin 3-O-beta-D-glucoside + UDP


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Gallus gallus)


name: RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex (Homo sapiens)


name: YWHAB dimer dissociates from dephosphorylated RAF (Caenorhabditis elegans)


name: a globoside MSGG (d18:1(4E)) + CMP + H(+) => a globoside GalGb4Cer (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: glyoxylate + L-glutamine <=> 2-oxoglutaramate + glycine


name: 2 hydrogencarbonate(out) + oxalate(in) => 2 hydrogencarbonate(in) + oxalate(out)


name: beta-alanyl-CoA <=> acryloyl-CoA + NH4(+)


name: Endonucleolytic RISC hydrolyzes target RNAs (Homo sapiens)


name: L-histidyl-[protein] + phosphoenolpyruvate => N(pros)-phospho-L-histidyl-[protein] + pyruvate


name: 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Homo sapiens)


name: ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A <=> ADP + H(+) + lipid A-core


name: adenosine 5'-phosphoramidate + 2 H(+) + sulfate => adenosine 5'-phosphosulfate + NH4(+)


name: 7-methylxanthine + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + theobromine


name: (1R,2R,3R)-prephytoene diphosphate = 15-cis-phytoene + diphosphate


name: (2E,6E)-farnesyl diphosphate <=> bicyclogermacrene + diphosphate


name: H2O + O2 + spermidine = 4-aminobutanal + H2O2 + propane-1,3-diamine


name: Reduction of desmosterol to cholesterol (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine <=> 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: ETA is phosphorylated to PETA by CHK/ETNK (Caenorhabditis elegans)


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA <=> (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O


name: 2 H(+) + hexadecanoyl-[ACP] + 2 NADPH <=> hexadecan-1-ol + holo-[ACP] + 2 NADP(+)


name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Drosophila melanogaster)


name: 2 Fe(II)-[cytochrome c] + H(+) + NADP(+) => 2 Fe(III)-[cytochrome c] + NADPH


name: (3R)-3-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O