name: ADP + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP


name: Sec-tRNA(Sec) binds to EEFSEC:GTP (Homo sapiens)


name: GGA3 associates with activated MET receptor (Caenorhabditis elegans)


name: Transfer of ubiquitin from E1 to E2 (Sus scrofa)


name: RAS GEFs promote RAS nucleotide exchange (Rattus norvegicus)


name: CO2 + H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NADP(+) => (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 3 H(+) + NADPH


name: PI3K synthesizes PIP3 downstream of ALK (Sus scrofa)


name: 18-hydroxy-(9Z)-octadecenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9Z)-octadecenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: ATP + glycine + tRNA(Gly) => AMP + diphosphate + glycyl-tRNA(Gly)


name: Mcm4,6,7 trimer forms and associates with the replication fork (Homo sapiens)


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Sus scrofa)


name: 4-(methylamino)butanoate + H2O + O2 => H2O2 + methylamine + succinate semialdehyde


name: [phosphate](n-1) + D-glucose 6-phosphate + H(+) => [phosphate](n) + D-glucose


name: PM20D1 hydrolyzes oleoyl-phe (Rattus norvegicus)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Sus scrofa)


name: 5,6-dihydrouracil + H2O <=> 3-(carbamoylamino)propanoate + H(+)


name: SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Drosophila melanogaster)


name: Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Drosophila melanogaster)


name: PIAS4 SUMOylates HERC2 with SUMO1 (Xenopus tropicalis)


name: 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine => anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine


name: benzyl thiocyanate + sulfate => (Z)-phenyl-N-(sulfonatooxy)methanimidothioate


name: Activation of JAK kinases (Mus musculus)


name: Edited Kainate Receptor binds glutamate (Canis familiaris)


name: CYP4 ω-oxidises 14(R)-HDHA to MaR-L2 (Homo sapiens)


name: 4 norrubrofusarin + O2 => 2 H2O + 2 ustilaginoidin A


name: 1D-myo-inositol 3-phosphate + CDP-2,3-bis-O-(phytanyl)-sn-glycerol = CMP + H(+) + saturated 1-archaetidyl-1D-myo-inositol 3-phosphate


name: RAB5 and GAPVD1 bind AP-2 (Gallus gallus)


name: A + D-gluconate <=> 2-dehydro-D-gluconate + AH2


name: Ca permeable AMPA receptor ligand binding (Canis familiaris)


name: a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 <=> a (8S,9R)-5-glyceryl-2'-deoxycytidine in DNA + CO2 + glyoxylate


name: CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Drosophila melanogaster)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Gallus gallus)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Mus musculus)


name: 3,4-dehydrothiomorpholine-3-carboxylate + 2 H(+) + NADH => (3R)-1,4-thiomorpholine-3-carboxylate + NAD(+)


name: 2 Na(+)(in) + phosphate(in) => 2 Na(+)(out) + phosphate(out)


name: CoA + H(+) + N(6)-propanoyl-L-lysyl-[protein] => L-lysyl-[protein] + propanoyl-CoA


name: XYLTs transfer Xyl to core protein (Sus scrofa)


name: 2-deoxystreptamine + 2-oxoglutaramate => 3-amino-2,3-dideoxy-scyllo-inosose + L-glutamine


name: beta-D-fructose 6-phosphate => D-glyceraldehyde 3-phosphate + dihydroxyacetone


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Drosophila melanogaster)


name: Association of procollagen type XXII (Rattus norvegicus)


name: SMURF2 binds SMAD3 phosphorylated in the linker region (Canis familiaris)


name: ATP + H(+) + L-glutamate + NADPH => ADP + L-glutamate 5-semialdehyde + NADP(+) + phosphate


name: H2O + N(2)-(3-hydroxy-3-methylhexanoyl)-L-glutaminate <=> 3-hydroxy-3-methylhexanoate + L-glutamine


name: CYP2F1 dehydrogenates 3-methylindole (Mus musculus)


name: ARL2:GTP bind PDE6D on KRAS4B (Sus scrofa)


name: chloride + L-tyrosine + NADP(+) <=> 3-chloro-L-tyrosine + NADPH


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Bos taurus)


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H(+) + NADPH = (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: 2-oxoglutaramate + H2O2 + NH4(+) => H2O + L-glutamine + O2


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Sus scrofa)


name: GSTO dimers reduce DeHA to AscH- (Rattus norvegicus)


name: 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA <=> 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: creatinine(in) + H(+)(out) <=> creatinine(out) + H(+)(in)


name: Extracellular KSPG translocates to the lysosome for degradation (Homo sapiens)


name: CO2 + phosphate + phosphoenolpyruvate => diphosphate + oxaloacetate


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Caenorhabditis elegans)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Mus musculus)


name: RAC1 and CDC42 activate PAK2 (Dictyostelium discoideum)


name: (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + CO2 + CoA


name: (9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: butanoate + NAD(+) = (2E)-2-butenoate + H(+) + NADH


name: an N-(fatty acyl)-L-glutamine + H2O <=> a fatty acid + L-glutamine


name: (7Z)-tetradecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(9Z)-hexadecenoyl-[ACP] + CO2 + holo-[ACP]


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Drosophila melanogaster)


name: 2 H(+) + NADPH + precorrin-6A => NADP(+) + precorrin-6B


name: ATP + L-aspartyl-tRNA(Asn) <=> 4-phosphooxy-L-aspartyl-tRNA(Asn) + ADP + H(+)


name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 (Dictyostelium discoideum)


name: Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Sus scrofa)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP


name: 5'-deoxyadenosine + phosphate = 5-deoxy-alpha-D-ribose 1-phosphate + adenine


name: PARVB interacts with Alpha-actinin (Sus scrofa)


name: (2R)-3-sulfolactate + NADP(+) <=> 3-sulfopyruvate + H(+) + NADPH


name: InhibinA-TGFBR3 binding to ACVR2A (Gallus gallus)


name: 2-oxobutanoate + L-glutamine => (2S)-2-aminobutanoate + 2-oxoglutaramate


name: UGCG transfers glucose to ceramide (Xenopus tropicalis)


name: GNRHR binds GNRHR peptide antagonists (Danio rerio)


name: glyoxal + H2O + O2 <=> glyoxylate + H(+) + H2O2


name: ZIP8 mediates zinc influx into cells (Homo sapiens)


name: Interaction of integrin alpha9beta1 with Tenascin-C (Xenopus tropicalis)


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Bos taurus)


name: 5-hydroxyoctan-4-one + H(+) + NADH + NH4(+) => 5-hydroxyoctan-4-amine + H2O + NAD(+)


name: 2 glutathione amide + H2O2 <=> glutathione amide disulfide + 2 H2O


name: GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol (Sus scrofa)


name: (2R)-3-phosphoglycerate + an NDP-alpha-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + a ribonucleoside 5'-diphosphate + H(+)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Dictyostelium discoideum)


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O => 1-O-alkyl-3-acyl-sn-glycerol + a fatty acid + H(+)


name: hexadecanoyl-CoA + sphinga-(4E,8Z)-dienine = CoA + H(+) + N-hexadecanoylsphinga-(4E,8Z)-dienine


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Caenorhabditis elegans)


name: CLCN4/5/6 exchange Cl- for H+ (Canis familiaris)


name: TGFBR3 complex binds to TGFBR2 (Xenopus tropicalis)


name: CDK1 phosphorylates LPIN (Xenopus tropicalis)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate => alpha-Kdo-(2->4)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADPH + O2 => (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: RHOD translocates to the mitochondrial outer membrane (Rattus norvegicus)


name: SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 is endocytosed (Homo sapiens)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Mus musculus)


name: 2-oxoglutarate + CoA + NADP(+) <=> CO2 + NADPH + succinyl-CoA


name: RBP3 regulates atROL taken up by Muller cells (Mus musculus)


name: ATG12 binds ATG7 dimer (Drosophila melanogaster)


name: acetaldehyde + dopamine => (R)-salsolinol + H2O


name: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)


name: mRNA6 is translated to protein 6 (Homo sapiens)


name: NF-kappaB translocates from the cytosol to the nucleus (Mus musculus)


name: a uridine in RNA = a pseudouridine in RNA


name: PROT mediates L-proline uptake (Caenorhabditis elegans)


name: MDM2 translocates to the nucleus (Bos taurus)


name: DAG stimulates protein kinase C-delta (Saccharomyces cerevisiae)


name: Vesicular inhibitory amino acid transport (Rattus norvegicus)


name: (3R)-3-isocyanylbutanoyl-AMP + holo-[ACP] = (3R)-3-isocyanylbutanoyl-[ACP] + AMP + H(+)


name: DAG kinase produces phosphatidic acid from DAG (Caenorhabditis elegans)


name: 15-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate => (8Z,11Z,14Z)-eicosatrienoate + O2


name: SUMOylation of NR1I2 with SUMO3 (Homo sapiens)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(27)-[histone H3] + O2 => CO2 + formaldehyde + L-lysyl(27)-[histone H3] + succinate


name: Release of 40S and 60S subunits from the 80S ribosome  (Schizosaccharomyces pombe)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Xenopus tropicalis)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Gallus gallus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate


name: dehydroepiandrosterone 3-sulfate + H2O => 3beta-hydroxyandrost-5-en-17-one + H(+) + sulfate


name: (R)-mandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + phenylacetonitrile + reduced [NADPH--hemoprotein reductase]


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Danio rerio)


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Homo sapiens)


name: CASP8 cleaves N4BP1 at D424, D490 (Canis familiaris)


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Xenopus tropicalis)


name: AADAC deacetylates PHEN (Rattus norvegicus)


name: (R)-tetraprenyl-beta-curcumene + H2O => sporulenol


name: Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Danio rerio)


name: 4-hydroxy-N-methyltryptamine 4-phosphate + S-adenosyl-L-methionine = H(+) + psilocybin + S-adenosyl-L-homocysteine


name: Aggrecan binds Hyaluronan and HAPLN1 (Bos taurus)


name: arginine + glycine => ornithine + guanidoacetate (Rattus norvegicus)


name: Recruitment of SHC1 is mediated by Y593 of the common beta chain (Mus musculus)


name: Collagen type XVIII endostatin release (Canis familiaris)


name: [3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose + GDP-alpha-D-mannose => alpha-D-mannosyl-(1->4)-[3-O-methyl-alpha-D-mannosyl-(1->4)](n)-3-O-methyl-D-mannose + GDP + H(+)


name: H(+) + L-serine + sn-glycerol 3-phosphate => H2O + sn-glycero-3-phospho-L-serine


name: BAP1 binds BRCA1:BARD1 heterodimer (Mus musculus)


name: ESR-associated SRC autophosphorylates (Danio rerio)


name: Phosphorylation of MDM4 by CHEK2 (Mus musculus)


name: NFkB binds the NFE2L2 gene (Homo sapiens)


name: RAC3 binds effectors at the plasma membrane (Xenopus tropicalis)


name: GTSE1 binds microtubule lattice in interphase cells (Bos taurus)


name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria (Danio rerio)


name: Phosphorylation of Cyclin B1 in the CRS domain (Mus musculus)


name: LCMT2 methoxycarbonylates OHyW-72 yielding OHyW (hydroxywybutosine) at nucleotide 37 of tRNA(Phe) (Homo sapiens)


name: PIAS3 SUMOylates PGR with SUMO1 (Homo sapiens)


name: SUMOylation of ING2 with SUMO1 (Saccharomyces cerevisiae)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Xenopus tropicalis)


name: ATM phosphorylates MDM2 (Rattus norvegicus)


name: glycine + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] <=> CO2 + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein]


name: (9Z)-octadecenoate + O2 = (8R)-hydroperoxy-(9Z)-octadecenoate


name: leukotriene C4(out) = leukotriene C4(in)


name: GSDMD forms ring‐shaped oligomers  (Gallus gallus)


name: a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:0) + H2O <=> a neolactoside nLc4Cer(d18:0) + L-fucose


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Mus musculus)


name: Beta-catenin migrates to the nucleus (Canis familiaris)


name: H2O + N-formimidoyl-L-glutamate <=> formamide + L-glutamate


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Drosophila melanogaster)


name: Disassembly of viral capsid (Homo sapiens)


name: GALNT3 transfers GalNAc to FGF23 (Homo sapiens)


name: Inactivation of Myt1 kinase (Saccharomyces cerevisiae)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Canis familiaris)


name: 5-methylcytidine(1404) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(1404) in 16S rRNA + S-adenosyl-L-methionine


name: calcitetrol + H2O + 2 oxidized [adrenodoxin] => 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol


name: NUDT16 hydrolyses IDP to IMP (Bos taurus)


name: 1,4-alpha-glucan branching enzyme activity


name: 4-hydroxy-3-[(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-2-one + H(+) + NADPH + O2 <=> 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H2O + NADP(+)


name: Joining of adjacent Okazaki fragments (Mus musculus)


name: 3-dehydro-6-deoxoteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase]


name: H(+)(out) + L-leucyl-L-proline(out) = H(+)(in) + L-leucyl-L-proline(in)


name: [(1->4)-alpha-D-galacturonosyl](n-2) + alpha-D-galacturonosyl-(1->4)-D-galacturonate => [(1->4)-alpha-D-galacturonosyl](n) + H2O


name: 2 CO2 + H2O + pentalenolactone F + 2 succinate => 2 2-oxoglutarate + 2 O2 + pentalenolactone D


name: an L-alpha-amino acid(in) + L-kynurenine(out) => an L-alpha-amino acid(out) + L-kynurenine(in)


name: D-fucose(in) + H(+)(in) => D-fucose(out) + H(+)(out)


name: Autocatalytic phosphorylation of FGFR1c P252X mutant dimers (Homo sapiens)


name: I(1,4,5)P3 binds ITPR3 tetramer (Sus scrofa)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Rattus norvegicus)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = phenylacetonitrile + sulfate + sulfur


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Bos taurus)


name: 4-nitrocatechol + H2O + NADP(+) => 4-nitrophenol + H(+) + NADPH + O2


name: dimethylallyl diphosphate + H2O = diphosphate + prenol


name: Clathrin internalises EPH:EFN complexes (Caenorhabditis elegans)


name: 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA => a 1-acyl-sn-glycero-3-phosphate + hexadecanoyl-CoA


name: SUMOylation of TFAP2C with SUMO1 (Rattus norvegicus)


name: p-STAT1 dimerizes (Caenorhabditis elegans)


name: acetoacetyl-CoA + acetyl-CoA + H2O <=> (3S)-hydroxy-3-methylglutaryl-CoA + CoA + H(+)


name: an N-(fatty acyl)-L-methionine + H2O <=> a fatty acid + L-methionine


name: CO2 + homogentisate => 3-(4-hydroxyphenyl)pyruvate + O2


name: Expression of SNAI1 during gastrulation (Homo sapiens)


name: Caspase cleavage of DCC (Canis familiaris)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: Dissociation of Cdc20 from APC/C complex (Drosophila melanogaster)


name: chloride(out) + L-arginine(out) + 2 Na(+)(out) = chloride(in) + L-arginine(in) + 2 Na(+)(in)


name: 2-hydroxyeicosanoate + 2 Fe(III)-[cytochrome b5] + H2O => eicosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: PLC beta-mediated PIP2 hydrolysis (Canis familiaris)


name: Elongation by POLH (Saccharomyces cerevisiae)


name: cob(I)alamin-[alkylcobalamin reductase] + H(+) + S-methyl glutathione => apo-[alkylcobalamin reductase] + glutathione + methylcob(III)alamin


name: 2 H(+) + 2 phosphate + UMP => 2 H2O + UTP


name: a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-GMP => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O


name: (3S)-3-hydroxy-D-aspartate = glycine + glyoxylate


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Mus musculus)


name: 3,16-dihydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3-hydroxyhexadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: OTUD5 deubiquitinates TRAF3 (Homo sapiens)


name: HuR binds mRNAs in the nucleus (Mus musculus)


name: IL21 receptor STAT binding (Homo sapiens)


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Homo sapiens)


name: cyclin-dependent protein serine/threonine kinase regulator activity


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Homo sapiens)


name: ALDH7A1 oxidises BETALD to BET (Dictyostelium discoideum)


name: 9-cis-retinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 9-cis-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADPH + tropinone => NADP(+) + pseudotropine


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Caenorhabditis elegans)


name: 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + secoxyloganin => O2 + reduced [NADPH--hemoprotein reductase] + secologanin


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Rattus norvegicus)


name: cadaverine(in) + H(+)(in) => cadaverine(out) + H(+)(out)


name: (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin => GMP + H(+) + oxidized coenzyme F420-0


name: Release of E3 from polyubiquitinated substrate (Plasmodium falciparum)


name: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] => (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H(+) + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase]


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine) => H(+) + holo-[aryl-carrier protein] + petrobactin


name: (2S)-2-amino-2'-deoxyadenylo-succinate <=> dZMP + fumarate


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Mus musculus)


name: 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)


name: H2O + N-acetyl-D-glucosamine 6-phosphate <=> acetate + D-glucosamine 6-phosphate


name: [protein]-disulfide + H(+) + NADPH => [protein]-dithiol + NADP(+)


name: L-2,4-diaminobutanoate + pyruvate => L-alanine + L-aspartate 4-semialdehyde


name: ADP-L-glycero-beta-D-manno-heptose + L-seryl-[protein] <=> ADP + H(+) + O-(L-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein]


name: a fatty acyl-CoA + sphinganine => an N-acylsphinganine + CoA + H(+)


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Homo sapiens)


name: Formation of classical C5 convertase (Gallus gallus)


name: 2-oxoglutarate + L-prolyl-[collagen] + O2 <=> CO2 + succinate + trans-3-hydroxy-L-prolyl-[collagen]


name: USP28 deubiquitinates CLSPN and MYC (Sus scrofa)


name: (E)-2-methylgeranyl diphosphate + H2O <=> 2-methylisoborneol + diphosphate


name: [protein-PII]-L-tyrosine + H(+) + UMP => [protein-PII]-uridylyl-L-tyrosine + H2O


name: 5 AH2 + 2 H(+) + heme b + 4 O2 <=> 5 A + delta-staphylobilin + Fe(2+) + formaldehyde + 4 H2O


name: O2 + octadecanoate + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2R)-3-sulfolactate + NAD(+) = 3-sulfopyruvate + H(+) + NADH


name: ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (Homo sapiens)


name: MPG glycosylase mediated recognition and binding of ethenoadenine  (Homo sapiens)


name: histone H3K9me/H3K9me2 demethylase activity


name: KIR2DL1 interacting with HLA-C group 2 (Cw3) (Bos taurus)


name: (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + NADP(+) => (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H(+) + NADPH


name: at-retinyl is hydrolysed from p-MII:SAG to release atRAL (Canis familiaris)


name: H2O + P(1),P(2)-bis(5'-adenosyl) diphosphate => 2 AMP + 2 H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate


name: Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants (Homo sapiens)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Sus scrofa)


name: Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)


name: betaenone C + 3 H2O + 3 NADP(+) => dehydroprobetaenone I + 3 H(+) + 3 NADPH + 3 O2


name: CoA + N-acetylimidazole => 1H-imidazole + acetyl-CoA


name: L-alanine(in) + L-cysteine(out) <=> L-alanine(out) + L-cysteine(in)


name: a ganglioside GM3 + H2O <=> an N-acyl-sphingoid base + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose


name: Gq-BTK complex dissociates to Active BTK and Gq (Rattus norvegicus)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Caenorhabditis elegans)


name: (S)-2-benzoylsuccinyl-CoA + CoA => benzoyl-CoA + succinyl-CoA


name: an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose = a mannosylinositol-1-phosphoceramide + GDP + H(+)


name: Collagen type VIII degradation by MMP1 (Rattus norvegicus)


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Rattus norvegicus)


name: TRAF6 is auto-ubiquitinated (Homo sapiens)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Sus scrofa)


name: Dual mechanism MAPK inhibitors bind MAPKs (Rattus norvegicus)


name: a 12-hydroxyjasmonyl-L-alpha-amino acid + O2 + reduced [NADPH--hemoprotein reductase] <=> a 12-oxojasmonyl-L-alpha-amino acid + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1,3-diacylglycerol + a 1-acylglycerol <=> a triacylglycerol + glycerol


name: Caspase 8 or 10 recruitment to IPS1 complex followed by their dimerization (Gallus gallus)


name: Aquaporin-1 passively transports water out of cell (Plasmodium falciparum)


name: glycine(in) + L-alanine(out) => glycine(out) + L-alanine(in)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Mus musculus)


name: COQ4 decarboxylates MHDB (Caenorhabditis elegans)


name: a dolichyl phosphate + beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H(+) => a dolichyl beta-D-glucosyl phosphate + chenodeoxycholate


name: ATP + H(+) + IC-asc-C7 => diphosphate + IC-asc-C7-AMP


name: 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + AH2 + O2 => 3-demethylubiquinol-8 + A + H2O


name: GOT2 dimer deaminates L-Asp (Drosophila melanogaster)


name: enterobactin + H2O => N-(2,3-dihydroxybenzoyl)-L-serine trimer


name: bifonsecin B + 2 H2O + NADP(+) => 2 fonsecin B + H(+) + NADPH + O2


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Rattus norvegicus)


name: p-BMAL1:p-CLOCK,NPAS2 binds F7 gene (Homo sapiens)


name: SPINK5(490-624) binds KLK5 (Homo sapiens)


name: MET bound PI3K generates PIP3 (Xenopus tropicalis)


name: p-6Y-VEGFR2 binds PLCG1 (Canis familiaris)


name: Loading of PCNA - Sliding Clamp Formation (Saccharomyces cerevisiae)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Canis familiaris)


name: MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)


name: RHOC activates endoplasmic reticulum effectors (Schizosaccharomyces pombe)


name: an 11beta-hydroxysteroid + NAD(+) => an 11-oxosteroid + H(+) + NADH


name: chenodeoxycholate + NAD(+) = 3-oxochenodeoxycholate + H(+) + NADH


name: 2-hydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin


name: eNoSC deacetylates histone H3 (Homo sapiens)


name: 7-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: ZSWIM8 ubiquitinates ROBO3.1 (Homo sapiens)


name: trypanothione-disulfide reductase (NADPH) activity


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Mus musculus)


name: Furin cleaves pro-factor X to factor X (Mus musculus)


name: AP2 binds chlorpromazine (Canis familiaris)


name: butanoate(out) + 2 Na(+)(out) = butanoate(in) + 2 Na(+)(in)


name: rebaudioside D + UDP-alpha-D-glucose <=> H(+) + rebaudioside M + UDP


name: D-phenylalanine + H2O + O2 <=> 3-phenylpyruvate + H2O2 + NH4(+)


name: D-glucurono-3,6-lactone + 2 H2O + NAD(+) <=> D-glucarate + 3 H(+) + NADH


name: (glutathione)4[2Fe(III)-2S] cluster(in) + ATP + H2O = (glutathione)4[2Fe(III)-2S] cluster(out) + ADP + H(+) + phosphate


name: MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Canis familiaris)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP


name: Passive I- efflux mediated by SLC5A8 (Rattus norvegicus)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Canis familiaris)


name: 3 AH2 + 2 H(+) + heme b + 3 O2 <=> 3 A + biliverdin IXbeta + CO + Fe(2+) + 3 H2O


name: DHCR24 reduces LAN to 24,25-dhLAN (Caenorhabditis elegans)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: SYK binds to p-Y65,Y76-FCER1G (Canis familiaris)


name: 15-methylhexadecasphing-4-enine + ATP <=> 15-methylhexadecasphing-4-enine 1-phosphate + ADP + H(+)


name: NAD(+) + trans,octa-cis-decaprenylphospho-beta-D-arabinofuranose = H(+) + NADH + trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose


name: RB1 recruits APC/C:Cdh1 complex to SKP2 (Rattus norvegicus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H(+)


name: ARFRP1 recruits ARL1 to the TGN (Saccharomyces cerevisiae)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Drosophila melanogaster)


name: 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol


name: 11-cis-retinyl hexadecanoate + H2O <=> 11-cis-retinol + H(+) + hexadecanoate


name: (S)-dihydroorotate + A <=> AH2 + orotate


name: ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide => 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Gallus gallus)


name: CYP2D6 4-hydroxylates debrisoquine (Homo sapiens)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Sus scrofa)


name: SLC29A1 transports RBV from extracellular region to cytosol (Mus musculus)


name: ATP + CoA + hexacosanoate => AMP + diphosphate + hexacosanoyl-CoA


name: ANKLE2 is deacetylated by SIRT2 (Danio rerio)


name: p-S10 CDKN1B translocates to the cytosol (Caenorhabditis elegans)


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)


name: pregnenolone + UDP-alpha-D-glucose <=> H(+) + pregnenolone 3-beta-D-glucoside + UDP


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Homo sapiens)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a cardiolipin


name: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA <=> acetyl-CoA + vanillin


name: H2O + O-phospho-L-threonyl-[protein] <=> L-threonyl-[protein] + phosphate


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Xenopus tropicalis)


name: 2 ADP + chlorophyllide a + oxidized 2[4Fe-4S]-[ferredoxin] + 2 phosphate <=> 2 ATP + 2 H2O + protochlorophyllide a + reduced 2[4Fe-4S]-[ferredoxin]


name: NAD(+) + xylitol => D-xylulose + H(+) + NADH


name: CFTR transits to the plasma membrane (Bos taurus)


name: Binding of ATP to P2X receptors (Danio rerio)


name: acetone + H(+) + NADPH + O2 = H2O + methyl acetate + NADP(+)


name: "acetone monooxygenase (methyl acetate-forming)"


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Bos taurus)


name: EPS15 and HGS bind ubiquitinated MET (Sus scrofa)


name: (S)-1-phenylethylamine + acetate => (S)-N-acetyl-1-phenylethylamine + H2O


name: 2 H2O + NADP(+) + orlandin => 2 7-demethylsiderin + NADPH + O2


name: IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Mus musculus)


name: SUMOylation of Histone H4 with SUMO3 (Bos taurus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + tetradecanoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-tetradecanoyl-sn-glycerol + CoA


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Sus scrofa)


name: p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Mus musculus)


name: 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate (Homo sapiens)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Sus scrofa)


name: VRK1/VRK2 phosphorylate BANF1 (Rattus norvegicus)


name: SLC12A3 binds SLC12A3 inhibitors (Xenopus tropicalis)


name: Interaction of Csk with PAG (Rattus norvegicus)


name: eIF2 activation (Saccharomyces cerevisiae)


name: Syndecans 1, 2 & 4 bind VTN (Danio rerio)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Drosophila melanogaster)


name: (R)-3-(indol-3-yl)lactoyl-CoA <=> (E)-3-(indol-3-yl)acryloyl-CoA + H2O


name: SYK binds to integrin alphaIIb beta3 (Rattus norvegicus)


name: hexadecan-1-ol + octadecanoyl-CoA = CoA + hexadecanyl octadecanoate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(in) + ATP + H2O => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(out) + ADP + H(+) + phosphate


name: POLB-mediated DNA strand displacement synthesis (Rattus norvegicus)


name: ISGylation of host protein filamin B (Drosophila melanogaster)


name: CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)


name: Caspase mediated cleavage of APC (Gallus gallus)


name: (R)-benzodiazepinedione + 2 AMP + 2 diphosphate + H(+) => anthranilate + 2 ATP + L-tryptophan


name: Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex (Sus scrofa)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Xenopus tropicalis)


name: MAPK6 is degraded by the 26S proteasome (Saccharomyces cerevisiae)


name: Syndecans 1, 2 & 4 bind VTN (Mus musculus)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Bos taurus)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Canis familiaris)


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Sus scrofa)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Canis familiaris)


name: H(+) + NADPH + progesterone => 5beta-pregnan-3,20-dione + NADP(+)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Rattus norvegicus)


name: Interaction of Tie2 and Shp2 (Homo sapiens)


name: FMN-N(5)-oxide + H(+) + NADH = FMN + H2O + NAD(+)


name: PICALM binds R-SNAREs (Caenorhabditis elegans)


name: PRDX5 reduces peroxynitrite to nitrite using TXN (Bos taurus)


name: UGT1A10 transfers GlcA from UDP-GlcA to GCTN (Rattus norvegicus)


name: RHOT1 binds effectors at the mitochondrial outer membrane (Canis familiaris)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: gibberellin A15 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => gibberellin A24 + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (E)-alk-1-en-1-SO-peroxol => (Z)-alkanethial oxide


name: 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + neopikromycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H2O + L-glutamate + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 2-oxoglutarate + 2 H(+) + NH4(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: COQ2 ligates all-E-10PrP2 to PHB (Saccharomyces cerevisiae)


name: MTRR reduces cob(II)alamin to meCbl (Dictyostelium discoideum)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Rattus norvegicus)


name: SULT1A1 dimer sulfonates NHABP (Rattus norvegicus)


name: Prolactin-releasing hormone receptor binds PRH (Rattus norvegicus)


name: UDP-alpha-D-galactose(in) + UDP-alpha-D-glucose(out) => UDP-alpha-D-galactose(out) + UDP-alpha-D-glucose(in)


name: acetate + vanillin => (E)-ferulate + H2O


name: ATP + CoA + salicylate <=> 2-hydroxybenzoyl-CoA + AMP + diphosphate


name: 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate


name: H2O + nigerose <=> alpha-D-glucose + D-glucose


name: Nucleotide exchange on RAB1 (Caenorhabditis elegans)


name: L-arginine(in) + L-lysine(out) <=> L-arginine(out) + L-lysine(in)


name: asc-omegaDeltaC7-CoA + H2O2 => asc-omegaC7-CoA + O2


name: Defective LARGE does not transfer Xyl from UDP-Xyl to GlcA (Homo sapiens)


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Drosophila melanogaster)


name: a ganglioside GQ1c + H2O = a ganglioside GT1c + N-acetylneuraminate


name: alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+) => alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose


name: Bradykinin receptors B1 and B2 bind to bradykinin (Homo sapiens)


name: 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + silphinene-15-oate => 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + silphinene


name: CHOL translocates from lysosome membrane to ER membrane (Xenopus tropicalis)


name: D-arginine + H2O + O2 = 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: PCBP4 modulates CDKN1A translation (Homo sapiens)


name: Dissociation of clathrin-associated proteins (Homo sapiens)


name: H(+) + NAD(+) + reduced 2[4Fe-4S]-[ferredoxin] = NADH + oxidized 2[4Fe-4S]-[ferredoxin]


name: SREBP1A,2 binds the DHCR7 promoter (Homo sapiens)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Schizosaccharomyces pombe)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Rattus norvegicus)


name: TP53 stimulates PMAIP1 (NOXA) expression (Homo sapiens)


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Caenorhabditis elegans)


name: TCF:Beta-catenin binds SOX proteins (Bos taurus)


name: CTLH E3 ligase ubiquitinates PKM-1 (Dictyostelium discoideum)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA <=> [O(7),N-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: RBP3 transports 11cRAL to rod photoreceptor outer segment (Mus musculus)


name: 2 H2O + 2 leukotriene A4 + O2 <=> 2 lipoxin A4


name: a ganglioside GT2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GT1c (d18:1(4E)) + H(+) + UDP


name: Active calmodulin binds CAMK2 (Mus musculus)


name: Elastin degradation by MMP14 (Mus musculus)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Rattus norvegicus)


name: USP33 deubiquitinates CCP110,ARRB (Drosophila melanogaster)


name: glycine(in) + H(+)(in) = glycine(out) + H(+)(out)


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Mus musculus)


name: SRD5A3 reduces pPNOL to DCHOL (Schizosaccharomyces pombe)


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + H(+)


name: Phosphorylated STATs are released (Sus scrofa)


name: (S)-tetrahydrocolumbamine + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-canadine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Rattus norvegicus)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Rattus norvegicus)


name: (6R)-L-erythro-6,7-dihydrobiopterin + (S)-4-hydroxymandelate + H2O => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + (S)-mandelate + O2


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: [(1->4)-beta-D-glucosyl](n) + GDP-alpha-D-glucose => [(1->4)-beta-D-glucosyl](n+1) + GDP + H(+)


name: Exocytosis of specific granule membrane proteins (Saccharomyces cerevisiae)


name: 2 H(+)(in) + H2 + menaquinone-8 <=> 2 H(+)(out) + menaquinol-8


name: 2 juglone + O2 => 2 3,5-dihydroxy-1,4-naphthoquinone + 2 H(+)


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Canis familiaris)


name: Formation of alternative pathway C5 convertase (Mus musculus)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Caenorhabditis elegans)


name: ADBRK1,2 phosphorylate AVPR2 (Sus scrofa)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: GSDMD forms ring‐shaped oligomers  (Homo sapiens)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Canis familiaris)


name: PLK1 phosphorylates GTSE1 (Homo sapiens)


name: Activated FGFR1 binds FRS2 (Xenopus tropicalis)


name: adenosine 3',5'-bisphosphate + H(+) + quercetin 3,4'-bissulfate => 3'-phosphoadenylyl sulfate + quercetin 3-sulfate


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Homo sapiens)


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Rattus norvegicus)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Rattus norvegicus)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Drosophila melanogaster)


name: a ganglioside Ac-O-8-GT3(d18:1(4E)) = a ganglioside Ac-O-9-GT3 (d18:1(4E))


name: hydrogen cyanide + nonanal <=> (2S)-2-hydroxydecanenitrile


name: a globoside Gb4Cer (d18:1(4E)) + H2O = a globoside Gb3Cer (d18:1(4E)) + N-acetyl-beta-D-galactosamine


name: phosphatidylinositol phosphate 5-phosphatase activity


name: Expression of DEC2 (BHLHE41, BHLHB3) (Homo sapiens)


name: Caspase-mediated cleavage of Etk (Homo sapiens)


name: HNP1-4 are released into phagocytic vacuoles (Rattus norvegicus)


name: 2-dehydro-D-gluconate + FADH2 => D-gluconate + FAD + H(+)


name: Passive I- efflux mediated by SLC5A8 (Mus musculus)


name: Factor IIa inhibitors (peptide) binds IIa (Canis familiaris)


name: 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+) => 1-hexanoyl-sn-glycero-3-phosphocholine + H2O


name: [(1->4)-alpha-D-glucosyl](n) + sucrose = [(1->4)-alpha-D-glucosyl](n+1) + D-fructose


name: (2E,11Z,14Z)-eicosatrienoyl-CoA + H(+) + NADPH = (11Z,14Z)-eicosadienoyl-CoA + NADP(+)


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Caenorhabditis elegans)


name: formyl-CoA + pentadecanal => (2R)-hydroxyhexadecanoyl-CoA


name: (2Z)-2-[(3,4-dioxocyclohexa-1,5-dien-1-yl)methylidene]-4-(4-hydroxyphenyl)-5-oxo-2,5-dihydrofuran-3-olate + H2O => aspulvinone E + O2


name: Defective ABCC8 does not form functional KATP channels, causing hyperinsulinemic hypoglycemia (Homo sapiens)


name: Interaction of integrin alphaDbeta2 with fibrin (Sus scrofa)


name: FAD + H(+) + sn-glycerol 3-phosphate <=> dihydroxyacetone phosphate + FADH2


name: LGI1 binds ADAM22 and ADAM23 (Sus scrofa)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Bos taurus)


name: 12-methyltridecanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one + 3 CO2 + 4 CoA


name: a (3R)-3-[(carboxymethyl)amino]fatty acid + H(+) + holo-[ACP] => a (2E)-enoyl-[ACP] + glycine + H2O


name: SOX9, NR5A1 (SF1), and GATA4 bind the AMH gene (Homo sapiens)


name: D-fructuronate(out) + H(+)(out) => D-fructuronate(in) + H(+)(in)


name: an N-terminal L-alpha-aminoacyl-[protein] + 3 S-adenosyl-L-methionine <=> an N-terminal trimethyl-L-alpha-aminoacyl-[protein] + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Bos taurus)


name: mRNA5 is translated to protein M (Homo sapiens)


name: Activated PLC gamma dissociates from the PDGF receptor (Homo sapiens)


name: Fatty acid ligands activate PPARA (Gallus gallus)


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)


name: (1S,5R)-carveol + NAD(+) <=> (R)-carvone + H(+) + NADH


name: 3,17-didehydrostemmadenine + H2O + NADPH => (16R)-deshydroxymethyl-stemmadenine + formate + NADP(+)


name: sphinga-(4E,8Z)-dienine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoylsphinga-(4E,8Z)-dienine


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Bos taurus)


name: MMP14 (MT1-MMP) binds TIMP2 (Danio rerio)


name: PGM1:Mg2+ isomerises G6P to G1P (Homo sapiens)


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + a ribonucleoside 5'-triphosphate => a 5'-end NTP-ribonucleotide-RNA + AMP + H(+)


name: (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA + NADP(+) => (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + H(+) + NADPH


name: Phosphorylated STAT92E dimer is dephosphorylated by PTP61F isoform 1 (Drosophila melanogaster)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Sus scrofa)


name: 2 fonsecin B + H(+) + NADPH + O2 = bifonsecin B + 2 H2O + NADP(+)


name: (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP


name: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + GDP + H(+)


name: AMP(in) + CMP-N-acetyl-beta-neuraminate(out) => AMP(out) + CMP-N-acetyl-beta-neuraminate(in)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Mus musculus)


name: L-arginine + L-cysteinyl-[NO transferase protein] + NADPH + 2 O2 = 2 H2O + L-citrulline + NADP(+) + S-nitroso-L-cysteinyl-[NO transferase protein]


name: STON2 binds SYT proteins (Caenorhabditis elegans)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Expression of HSPA8, ALOX15 (Homo sapiens)


name: Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA (Drosophila melanogaster)


name: FITM1, FITM2 bind TAGs (Caenorhabditis elegans)


name: ATF2 acetylates histone H2B, H4 (Gallus gallus)


name: dihexadecanoylglycerol + H(+) + hexadecanoate => H2O + trihexadecanoylglycerol


name: PGH2 is isomerised to PGE2 by PTGES (Drosophila melanogaster)


name: (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H(+) => 1,3-di-(9Z-octadecenoyl)-glycerol + H2O


name: HJURP:CENPA complex localizes to the centromere (Homo sapiens)


name: L-aspartate(in) + L-valine(out) => L-aspartate(out) + L-valine(in)


name: L-valine(out) + Na(+)(out) => L-valine(in) + Na(+)(in)


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Sus scrofa)


name: D-glutamate + H2O + NAD(+) => 2-oxoglutarate + H(+) + NADH + NH4(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone <=> 19-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N(omega)-hydroxy-L-arginine = 2 Fe(III)-[cytochrome b5] + H2O + L-arginine


name: estrone 3-sulfate(out) + n H(+)(out) => estrone 3-sulfate(in) + n H(+)(in)


name: 2-trans-(+)-abscisic aldehyde + H(+) + NADH => 2-trans,4-trans-xanthoxin + NAD(+)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O


name: UGT8 transfers Gal from UDP-Gal to CERA (Mus musculus)


name: IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Sus scrofa)


name: 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: Activation of proMMP7 by MMP3 (Mus musculus)


name: cortisol + H(+) + NADPH => 5beta-dihydrocortisol + NADP(+)


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Bos taurus)


name: RAN stimulates fusion of nuclear envelope (NE) membranes (Mus musculus)


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Caenorhabditis elegans)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Saccharomyces cerevisiae)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Canis familiaris)


name: 5,6,7,8-tetrahydropteridine + NADP(+) <=> 6,7-dihydropteridine + H(+) + NADPH


name: (S)-malyl alpha-D-glucosaminide + acetate => (S)-malyl N-acetyl-alpha-D-glucosaminide + H2O


name: (-)-phomoidride B + H(+) + methanol + S-adenosyl-L-homocysteine => phomoidride A + S-adenosyl-L-methionine


name: CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + H(+) => acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: DHFR dimer reduces FOLA to DHF (Saccharomyces cerevisiae)


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Dictyostelium discoideum)


name: (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + NAD(+) => (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H(+) + NADH


name: diphosphate + gamma-himachalene => (2E,6E)-farnesyl diphosphate


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Sus scrofa)


name: 4-hydroxy-3-all-trans-decaprenylbenzoate + H(+) = 2-all-trans-decaprenylphenol + CO2


name: beta-L-Ara4N-lipid A (E. coli) + di-trans,octa-cis-undecaprenyl phosphate => 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A (E. coli)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Homo sapiens)


name: Conversion of C2 into C2a and C2b (Rattus norvegicus)


name: O2 + preaspterpenacid acid I + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + preaspterpenacid acid II


name: (R)-pantolactone + NADP(+) <=> 2-dehydropantolactone + H(+) + NADPH


name: (9Z)-octadecenoyl-CoA + di-(9Z)-octadecenoylglycerol = 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA


name: 3-phenylpyruvate + H2O2 + NH4(+) => D-phenylalanine + H2O + O2


name: a ganglioside Ac-O-7-GD2 = a ganglioside Ac-O-8-GD2


name: Glutamine transport from astrocytes (Gallus gallus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> (-)-somaliensene B + diphosphate


name: RHOD:GTP recruits DAIPH2-3 to endosomes (Rattus norvegicus)


name: galactitol 1-phosphate + NAD(+) = H(+) + keto-L-tagatose 6-phosphate + NADH


name: AH2 + 5 H(+) + 5 malonyl-CoA => 6-hydroxymellein + A + 5 CO2 + 5 CoA + H2O


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Dictyostelium discoideum)


name: acetyl-CoA + 6 H(+) + 5 malonyl-CoA + 2 NADPH <=> 2-hydroxy-5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 3 H2O + 2 NADP(+)


name: H2O + methanethiol + O2 <=> formaldehyde + H(+) + H2O2 + hydrogen sulfide


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Sus scrofa)


name: RAC2 GDIs block activation of RAC2 (Homo sapiens)


name: P2Y11 receptor can bind to ATP (Bos taurus)


name: Fe(2+) + sirohydrochlorin => 2 H(+) + siroheme


name: Interaction of other adapter proteins with p-KIT (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycerol + H(+) => 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + H2O


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Rattus norvegicus)


name: SUMOylation of BLM with SUMO2,3 (Bos taurus)


name: H2O + N-acyl-L-aspartate => a carboxylate + L-aspartate


name: ALDH8A1 oxidises 9cRAL to 9cRA (Mus musculus)


name: 2-(hydroxyimino)propanoate + acetone => acetone oxime + pyruvate


name: Release of eIF4E from the inactive eIF4E:4E-BP complex  (Sus scrofa)


name: Factor H binds to membrane-associated C3b (Sus scrofa)


name: Src activation following P2Y purinoceptor activation (Caenorhabditis elegans)


name: NID1 degradation by MMP1, 9, 12, ELANE (Homo sapiens)


name: H(+) + octadecanoyl-CoA + oxidized [electron-transfer flavoprotein] = (2E)-octadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: HLCS biotinylates ACACA:Mn2+ (Rattus norvegicus)


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Rattus norvegicus)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate


name: Defective OPN1MW causes COD5 (Homo sapiens)


name: Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)


name: Histidine is decarboxylated to histamine (Drosophila melanogaster)


name: Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Bos taurus)


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Sus scrofa)


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Bos taurus)


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Sus scrofa)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Bos taurus)


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Mus musculus)


name: 1-O-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate + H(+) + hexadecanoate => (9Z,12Z,15Z)-octadecatrien-1-ol + 1-hexadecanoylglycerone 3-phosphate


name: NADP(+) + nicotinate => nicotinamide + nicotinate-adenine dinucleotide phosphate


name: (17Z)-hexacosenoyl-CoA + sphinganine = CoA + H(+) + N-[(17Z)-hexacosenoyl]dihydrosphingosine


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Sus scrofa)


name: H(+) + S-adenosyl-L-methionine => CO2 + S-adenosyl 3-(methylsulfanyl)propylamine


name: a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphate => a 2'-deoxyribonucleoside 5'-triphosphate + H2O


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Mus musculus)


name: (+)-sesamin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (+)-piperitol + O2 + reduced [NADPH--hemoprotein reductase]


name: Keratin tetramers bind to form unit length filaments (Danio rerio)


name: (7R)-7-(5-carboxy-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C


name: G-proteins dissociate from plasma-membrane estrogen receptors (Sus scrofa)


name: adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine <=> 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine


name: BIL translocates to the nucleus (Homo sapiens)


name: 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 H(+) + 2 phosphate => GTP + 3 H2O


name: 15-dehydro-prostaglandin I2 + H(+) + NADPH => NADP(+) + prostaglandin I2


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Rattus norvegicus)


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Canis familiaris)


name: Collagen type II binds integrin alpha10beta1 (Caenorhabditis elegans)


name: ent-kaur-16-en-19-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-kaur-16-en-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of hydroxylysyl-pyrrole cross-links (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A (E. coli) => a 1,2-diacyl-sn-glycerol + lipid A 4'-(2-aminoethyl diphosphate) (E. coli)


name: acetyl-CoA + N-terminal L-threonyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-threonyl-[protein]


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Schizosaccharomyces pombe)


name: 1,2,3-tri-(12R-hydroxy-9Z-octadecenoyl)-glycerol + CoA => (12R)-hydroxy-(9Z)-octadecenoyl-CoA + 1,2-di-(12R-hydroxy-9Z-octadecenoyl)-sn-glycerol


name: ABC-type doxorubicin transporter activity


name: 7-dehydrocholesterol + A + H2O = AH2 + cholesta-5,7-dien-3beta,25-diol


name: N(omega)-methyl-L-arginine + pyruvate <=> 5-(3-methylguanidino)-2-oxopentanoate + L-alanine


name: (2S)-2-amino-4-deoxychorismate + FMN <=> 3-(1-carboxyvinyloxy)anthranilate + FMNH2


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Dictyostelium discoideum)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Danio rerio)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol => a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol


name: 2-oxoglutarate(out) + oxaloacetate(in) => 2-oxoglutarate(in) + oxaloacetate(out)


name: CO2 + H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+) = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 3 H(+) + NADH


name: UDP-alpha-D-glucuronate + zolasartan => UDP + zolarsartan O-beta-D-glucuronoside


name: 3,3',5-triiodo-L-thyronine + A + H(+) + iodide <=> AH2 + L-thyroxine


name: ULK1 Translocates to the mitochondria (Rattus norvegicus)


name: an acyl-CoA + sn-glycerol 3-phosphate = a 2-acyl-sn-glycerol 3-phosphate + CoA


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-3-[beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 1-(9Z,12Z-octadecadienoyl)-2-acyl-3-[beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: proton motive force dependent protein transmembrane transporter activity


name: glucoraphanin + H2O = (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Mus musculus)


name: TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 (Homo sapiens)


name: guanosine(46) in tRNA + S-adenosyl-L-methionine <=> N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycerol + CDP-N-methylethanolamine => 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + CMP + H(+)


name: CBFB binds RUNX3 (Drosophila melanogaster)


name: SARS-CoV-2 nsp9 binds to 7SL RNA (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 <=> (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: ATP + H2O + sulfate(out) <=> ADP + H(+) + phosphate + sulfate(in)


name: ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Xenopus tropicalis)


name: ARFGAPs stimulate ARF GTPase activity (Canis familiaris)


name: (R)-salsolinol-1-carboxylate + H2O => dopamine + pyruvate


name: TP53 stimulates CASP6 expression (Homo sapiens)


name: AOX1 oxidises PXL to PDXate (Homo sapiens)


name: candesartan + UDP-alpha-D-glucuronate <=> candesartan-2-N-beta-D-glucuronide + UDP


name: (8S)-annullatin E + dimethylallyl diphosphate = (8S)-annullatin J + diphosphate


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Mus musculus)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Homo sapiens)


name: NAD(+) + reduced riboflavin => 2 H(+) + NADH + riboflavin


name: dimethylallyl diphosphate + harmol => 6-(3-dimethylallyl)harmol + diphosphate


name: methanol + o-quinone methide <=> hydroxyclavatol methyl ether


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Sus scrofa)


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Danio rerio)


name: CEBPA binds MYC gene:E2F1 (Homo sapiens)


name: beta-NGF dimer binds to TrkA receptor (Gallus gallus)


name: CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Mus musculus)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Bos taurus)


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP => 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP


name: RhCG mediates ammonium influx into kidney collecting duct cells (Gallus gallus)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Danio rerio)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + phosphate


name: G/U mismatch-specific uracil-DNA glycosylase activity


name: NSF ATPase activity dissociates cis-SNARE (Saccharomyces cerevisiae)


name: A + sucrose => 3-dehydro-alpha-D-glucosyl beta-D-fructofuranoside + AH2


name: Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Bos taurus)


name: ATP + H2O + L-alanyl-L-glutamine(out) <=> ADP + H(+) + L-alanyl-L-glutamine(in) + phosphate


name: β-blockers bind ADRB1,2,3 (Canis familiaris)


name: UVSSA:USP7 deubiquitinates ERCC6 (Saccharomyces cerevisiae)


name: WWP2 ubiquitinates NOTCH3 (Rattus norvegicus)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Dictyostelium discoideum)


name: 17alpha-hydroxywithaferin A + UDP-alpha-D-glucose <=> 17alpha-sitoindoside IX + H(+) + UDP


name: NAD(+) + taurochenodeoxycholate <=> 7-oxotaurolithocholate + H(+) + NADH


name: furfural + H2O + NADP(+) <=> 2-furoate + 2 H(+) + NADPH


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Homo sapiens)


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Caenorhabditis elegans)


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Gallus gallus)


name: Endorepellin binds KDR (VEGFR2) (Caenorhabditis elegans)


name: DCC interaction with Ezrin (Rattus norvegicus)


name: 9alpha-copalyl diphosphate + H2O = diphosphate + syn-copalol


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine => Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+) + H2O


name: COQ6 hydroxylates DHB (Dictyostelium discoideum)


name: 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine = 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: PDE4A hydrolyses cAMP to AMP (Xenopus tropicalis)


name: Hydrolysis of PIP2 by PLCG (Xenopus tropicalis)


name: SPRY2 is phosphorylated by phosphorylated MNK1 (Rattus norvegicus)


name: D-cellotrionate + H(+) => D-cellotriono-1,5-lactone + H2O


name: (E)-caffeoyl-CoA + S-adenosyl-L-methionine = (E)-feruloyl-CoA + H(+) + S-adenosyl-L-homocysteine


name: NLRP3 activation by small molecules (Danio rerio)


name: a disubstituted aliphatic (S)-hydroxynitrile => a ketone + hydrogen cyanide


name: ecdysone 22-phosphate + H2O <=> ecdysone + phosphate


name: USP5 cleaves polyubiquitin (Danio rerio)


name: "lytic cellulose monooxygenase (C1-hydroxylating)"


name: 19-hydroxytestosterone + O2 + reduced [NADPH--hemoprotein reductase] => 19-oxotestosterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2 <=> (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: (-)-vincadifformine + O2 + reduced [NADPH--hemoprotein reductase] => (-)-minovincinine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 7,8-dihydropteroate + diphosphate => (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate


name: Recruitment of XPA and release of CAK  (Mus musculus)


name: 2-hydroxyestrone + S-adenosyl-L-methionine => 2-methoxyestrone + H(+) + S-adenosyl-L-homocysteine


name: 5,6-dihydroquinoline-2,5,6-triol + NAD(+) => H(+) + NADH + O2 + quinolin-2-ol


name: ADP-alpha-D-glucose + D-glucose = ADP + alpha,alpha-trehalose + H(+)


name: (16R)-deshydroxymethyl-stemmadenine + formate => 17-dehydrostemmadenine + H2O


name: (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADH <=> H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Bos taurus)


name: a 1-acyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: Autocatalytic phosphorylation of FGFR4 (Gallus gallus)


name: AMP + diphosphate + L-tyrosinal + NADP(+) = ATP + H(+) + L-tyrosine + NADPH


name: (9Z,12Z)-octadecadienoyl-CoA + 2-(9Z-octadecenoyl)-glycerol <=> 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: Cho transports from the extracellular space to the cytosol (Sus scrofa)


name: Retinoic acid activates HOXA4 chromatin (Homo sapiens)


name: AMP(in) + UDP-alpha-D-galactose(out) => AMP(out) + UDP-alpha-D-galactose(in)


name: LARG activation by G alpha 12/13 (Mus musculus)


name: dihydroxyacetone + H(+) + NADPH => glycerol + NADP(+)


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Mus musculus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: Formation of caspase-1 p10/p20 dimer (Bos taurus)


name: oxalyl-CoA + succinate => oxalate + succinyl-CoA


name: PAK1,2,3 phosphorylates MAPK6,4 (Homo sapiens)


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Homo sapiens)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Plasmodium falciparum)


name: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + H2O <=> a neolactoside nLc4Cer(d18:1(4E)) + N-acetylneuraminate


name: ATP + H2O + L-cysteine(out) = ADP + H(+) + L-cysteine(in) + phosphate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] => 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylated PKN1 binds androgen receptor (AR) (Canis familiaris)


name: Formation of GINS complex (Mus musculus)


name: H2O + N-acetyl-L-lysine => acetate + L-lysine


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + H(+) + UDP => 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine


name: atRAL is reduced to atROL (Caenorhabditis elegans)


name: 2-hydroxy-4-methylpentanoate + O2 <=> 4-methyl-2-oxopentanoate + H2O2


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Drosophila melanogaster)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Saccharomyces cerevisiae)


name: FGFR1c binds to Klotho-bound FGF23 (Sus scrofa)


name: Connexin 45/Connexin 36 mediated neuronal gap junction communication (Rattus norvegicus)


name: 5,6-dihydrothymine + H2O => 3-(carbamoylamino)-2-methylpropanoate + H(+)


name: dGMP + H2O = 2'-deoxyguanosine + phosphate


name: ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Canis familiaris)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Bos taurus)


name: H(+) + phenylglyoxylate => benzaldehyde + CO2


name: 7(1)-hydroxychlorophyll a + NAD(+) => chlorophyll b + H(+) + NADH


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Danio rerio)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Danio rerio)


name: Self-ubiquitination of RNF41 (Gallus gallus)


name: PAK2 autophorylates (Xenopus tropicalis)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Homo sapiens)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Homo sapiens)


name: Activated FGFR2:p-FRS bind to PPTN11 (Canis familiaris)


name: SCF-FBXL18 ubiquitinates FBXL7 (Homo sapiens)


name: Separation of elongating transcript from template (Mus musculus)


name: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 <=> H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone


name: cholesterol + PAPS => cholesterol sulfate + PAP (Rattus norvegicus)


name: GST dimers cleave AZA to 6MP (Sus scrofa)


name: acetyl-CoA + L-methionine sulfone <=> CoA + H(+) + N-acetyl-L-methionine sulfone


name: 2,4-dinitroanisole + H2O => 2,4-dinitrophenol + H(+) + methanol


name: alpha-maltotetraose + beta-maltose <=> alpha-maltopentaose + beta-D-glucose


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Homo sapiens)


name: 3 AH2 + 2 H(+) + heme b + 3 O2 => 3 A + Fe(2+) + 3 H2O + mycobilin a


name: SUMOylation of TOP1 with SUMO1 (Sus scrofa)


name: 4-methoxybenzaldehyde + hydrogen cyanide => (2S)-2-hydroxy-2-(4-methoxyphenyl)acetonitrile


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Rattus norvegicus)


name: RNA demethylases demethylate N6-methyladenosine RNA (Mus musculus)


name: SRD5A2 dehydrogenates TEST to DHTEST (Mus musculus)


name: acetyl-CoA + D-glutamine => CoA + H(+) + N-acetyl-D-glutamine


name: 5-dehydroepisterol + H(+) + NADPH + O2 <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + 2 H2O + NADP(+)


name: Interleukin-12 dissociates from Interleukin-12 receptor (Canis familiaris)


name: Formation of the Rad17-RFC alternate clamp-loader complex (Gallus gallus)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Rattus norvegicus)


name: STUB1 (CHIP) ubiquitinates SMAD3 (Drosophila melanogaster)


name: H2O + N-benzoylglycine = benzoate + glycine


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Dictyostelium discoideum)


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Mus musculus)


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-(9Z,12Z-octadecadienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: SRF stimulates NPAS4 gene transcription (Homo sapiens)


name: Homodimerization of VEGF proteins (Gallus gallus)


name: GRB2-1:SOS1 binds p-Y-SHC (Rattus norvegicus)


name: SLITs bind keratan sulfate (Canis familiaris)


name: H2O + N-(aminomethyl)urea => N-(hydroxymethyl)urea + NH4(+)


name: Binding of SHC1 to insulin receptor (Rattus norvegicus)


name: NOTCH1 coactivator complex binds NOTCH3 gene (Homo sapiens)


name: CDK2:CCNA phosphorylates TERF2 (Mus musculus)


name: RIPK1 variant is not cleaved by CASP8 (Homo sapiens)


name: AFG3L2 degrades mitochondrial matrix proteins (Drosophila melanogaster)


name: H2O + indole-3-acetaldehyde + O2 => (indol-3-yl)acetate + H(+) + H2O2


name: D-ornithine(out) + L-ornithine(in) => D-ornithine(in) + L-ornithine(out)


name: Phosphorylation and activation of VAV (Xenopus tropicalis)


name: H(+) + taxiphyllin + UDP => 4-hydroxymandelonitrile + UDP-alpha-D-glucose


name: PTGS2 dimer oxidises EPA to PGH3 (Xenopus tropicalis)


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol <=> a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: BACE1 cleaves APP(18-770) to APP(18-671) and APP(672-770) (Homo sapiens)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Danio rerio)


name: XPO1-dependent export of p-S69,S73 MITF-M (Gallus gallus)


name: H(+) + H2O + N,N-dihydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase] => N-hydroxy-L-pentahomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: TP53RK phosphorylates TP53 (Homo sapiens)


name: PA is converted to CDP-DAG by CDS1 (Dictyostelium discoideum)


name: 4 monapinone E + O2 <=> 2 dinapinone E + 2 H2O


name: ATP(out) + UDP(in) => ATP(in) + UDP(out)


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Bos taurus)


name: adenosine(4220) in 28S rRNA + S-adenosyl-L-methionine => H(+) + N(6)-methyladenosine(4220) in 28S rRNA + S-adenosyl-L-homocysteine


name: RHOA GAPs stimulate RHOA GTPase activity (Rattus norvegicus)


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Sus scrofa)


name: 2',3'-cyclophospho-AMP + H2O <=> 3'-AMP + H(+)


name: RANBP2 SUMOylates MDM2 with SUMO1 (Homo sapiens)


name: Delta(1)-pyrroline-(4S)-hydroxy-2-carboxylate + 2 H(+) + NADPH => cis-4-hydroxy-L-proline + NADP(+)


name: GPIb:IX:V binds to VWF multimer:collagen (Sus scrofa)


name: HDAC8 deacetylates histones (Saccharomyces cerevisiae)


name: (9S,10R)-epoxy-octadecanoate + H2O <=> 9R,10R-dihydroxyoctadecanoate


name: RNA Polymerase II Promoter Opening: First Transition (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate


name: 2-oxoglutarate + D-kanosamine 6-phosphate => 3-dehydro-D-glucose 6-phosphate + L-glutamate


name: RAC2 GDIs block activation of RAC2 (Canis familiaris)


name: Oligomerization of BAX at the mitochondrial membrane (Sus scrofa)


name: an anthocyanidin 5-O-beta-D-glucoside 3-O-beta-D-sambubioside + H(+) + UDP => an anthocyanidin 3-O-beta-D-sambubioside + UDP-alpha-D-glucose


name: ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 (Homo sapiens)


name: episterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 5-dehydroepisterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a ganglioside GD3 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT3 (d18:1(4E)) + CMP + H(+)


name: a neolactoside IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + H(+) + UDP


name: Phosphorylation of PIP2 to PIP3 by PI3K (Sus scrofa)


name: Dissociation of the Gi alpha:G olf complex (Dictyostelium discoideum)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Xenopus tropicalis)


name: alpha-ribazole 5'-phosphate + H(+) + nicotinate => 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide


name: p-S54-PDE4B hydrolyses cAMP (Dictyostelium discoideum)


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Bos taurus)


name: cholesterol sulfate + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S)-hydroxycholesterol 3-sulfate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein) (Homo sapiens)


name: benzoate + H(+) + H2O2 => benzaldehyde + H2O + O2


name: BCDX2 complex stabilizes RAD51 filament (Homo sapiens)


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Caenorhabditis elegans)


name: S-(1-hydroxy-2-oxopropyl)-L-cysteinyl-[protein] => L-cysteinyl-[protein] + methylglyoxal


name: PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Bos taurus)


name: acetyl-CoA + AH2 + 3 H(+) + 3 malonyl-CoA => A + 3 CO2 + 4 CoA + H2O + orsellinaldehyde


name: UGTs glucuronate APAP to APAP-GlcA (Rattus norvegicus)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Bos taurus)


name: 3,6-dichloro-2-methoxybenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,6-dichlorosalicylate + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Gallus gallus)


name: AKR1C3 reduces atRAL to atROL (Caenorhabditis elegans)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Mus musculus)


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Xenopus tropicalis)


name: H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate


name: FMNH2 + N-methylnicotinate + O2 <=> (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+)


name: G alpha (q) inhibits PI3K alpha (Xenopus tropicalis)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-4-deoxy-4-formamido-beta-L-arabinose = 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + UDP


name: DCC interaction with Ezrin (Drosophila melanogaster)


name: H(+)(out) + sucrose(out) <=> H(+)(in) + sucrose(in)


name: Lipoxygenase dehydrogenates 7(S),17(S)-diHp-DHA to 7S(8)-epoxy-17(S)-HDHA (Homo sapiens)


name: ADP + cob(II)yrinate c monoamide + H(+) + L-glutamate + phosphate => ATP + cob(II)yrinate + H2O + L-glutamine


name: cyanate + H(+) + hydrogencarbonate <=> carbamate + CO2


name: FA anion flip-flops to the opposite surface (Bos taurus)


name: methylcytosine to 5-glyceryl-methylcytosine dioxygenase activity


name: 2 H(+) + L-2-aminoadipate + NADPH => (S)-2-amino-6-oxohexanoate + H2O + NADP(+)


name: a C29-steroid + O2 + reduced [NADPH--hemoprotein reductase] => a (22S)-22-hydroxy C29-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Trimming of peptides by IRAP in endocytic vesicles (Sus scrofa)


name: MAP2K2 binds MAPK1 (Caenorhabditis elegans)


name: D-ornithine(in) + L-ornithine(out) <=> D-ornithine(out) + L-ornithine(in)


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Homo sapiens)


name: PMM1,2 isomerise Man6P to Man1P (Gallus gallus)


name: GLYCTK phosphorylates DGA to 3PDGA (Sus scrofa)


name: Latent TGF-beta-3 binds integrins (Homo sapiens)


name: HLCS biotinylates ACACB (Drosophila melanogaster)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 <=> 5,10-methylenetetrahydromethanopterin + H(+)


name: methanesulfonate + NADH + O2 <=> formaldehyde + H2O + NAD(+) + sulfite


name: a 3beta-hydroxysteroid + a triacylglycerol <=> a 1,2-diacylglycerol + a 3beta-hydroxysteroid ester


name: CDC7 gene expression is repressed by the PRC1L4 complex (Homo sapiens)


name: a triacyl-sn-glycerol + H2O => a 1,3-diacyl-sn-glycerol + a fatty acid + H(+)


name: H2O + zearalenone = H(+) + hydrolyzed zearalenone


name: Glutamine transport from astrocytes (Bos taurus)


name: benzylamine + pyruvate => benzaldehyde + L-alanine


name: GTP-binding activates eEF2 (Homo sapiens)


name: RCE1 cleaves S-Farn proRAS proteins (Caenorhabditis elegans)


name: 2-oxoadipate + CoA + NAD(+) = CO2 + glutaryl-CoA + NADH


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Danio rerio)


name: 4-O-deacetylvindoline + acetyl-CoA = CoA + vindoline


name: serotonin-gated monoatomic cation channel activity


name: CoA + hexadecanal + NADP(+) => H(+) + hexadecanoyl-CoA + NADPH


name: L-arginine(in) + L-cysteine(out) + Na(+)(out) = L-arginine(out) + L-cysteine(in) + Na(+)(in)


name: Androgens binds AR (in the HSP90 chaperone complex) (Rattus norvegicus)


name: a ganglioside GM1b + CMP + H(+) => a ganglioside GA1 + CMP-N-acetyl-beta-neuraminate


name: UROD decarboxylates URO3 to COPRO3 (Xenopus tropicalis)


name: 7-chlorotetracycline + H(+) + NADPH + O2 = (1S,10S,10aS)-3-(CONH2)-9-Cl-1-(Me2N)-3,3a,4,10-(HO)4-10-Me-2,5-dioxo-1H,10aH,11H,11aH-cyclopenta[b]anthracen-6-olate + CO + H2O + NADP(+)


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Bos taurus)


name: BACH1 is phosphorylated at tyrosine 483 (Homo sapiens)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-4-phosphate) + H2O => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: Keratin type I binds keratin type II (Homo sapiens)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Gallus gallus)


name: D-glucosamine 6-phosphate + NADP(+) => 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + 2 H(+) + NADPH


name: 2-oxoglutarate(out) + estrone 3-sulfate(in) = 2-oxoglutarate(in) + estrone 3-sulfate(out)


name: 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O = 2 AMP + H(+)


name: SUMOylation of NFKBIA with SUMO1 (Rattus norvegicus)


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Homo sapiens)


name: EP2 and EP4 receptors can bind PGE2 (Rattus norvegicus)


name: a long chain fatty alcohol + a long-chain fatty acid + H(+) => a wax ester + H2O


name: 4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NADP(+) => 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + H(+) + NADPH


name: (2E)-hexacosenoyl-CoA + H(+) + NADPH <=> hexacosanoyl-CoA + NADP(+)


name: "cellulose 1,4-beta-cellobiosidase (non-reducing end)"


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + CoA + H(+)


name: ATP + H2O + L-isoleucine(out) => ADP + H(+) + L-isoleucine(in) + phosphate


name: an N(6)-alkylaminopurine + UDP-alpha-D-glucose = an N(6)-alkylamino-7-beta-D-glucosylpurine + H(+) + UDP


name: OCT3 mediates renal clearance of organic cations (Homo sapiens)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Sus scrofa)


name: inhibitory extracellular ligand-gated monoatomic ion channel activity


name: beta-D-mannopyranosyl-(1->2)-D-mannopyranose + phosphate = alpha-D-mannose 1-phosphate + D-mannose


name: 2-oxoglutarate + 3(1)-hydroxy-L-isoleucine + O2 = (4S)-3(1),4-dihydroxy-L-isoleucine + CO2 + succinate


name: EP300 acetylates histone H2A, H2B, H3, H4 (Gallus gallus)


name: (22R,23R)-22,23-dihydroxycampest-4-en-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (22R,23R)-22,23-dihydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: ATG7:ATG3:LC3 dissociates (Homo sapiens)


name: Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Bos taurus)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Mus musculus)


name: alpha-D-glucose 1-phosphate + GTP + H(+) = diphosphate + GDP-D-glucose


name: p-STAT1 binds p-STAT3 (Rattus norvegicus)


name: an N-acyl-(4R)-4-hydroxysphinganine + H2O => (4R)-hydroxysphinganine + a fatty acid


name: TP receptor can bind thromboxane (Danio rerio)


name: Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Canis familiaris)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Canis familiaris)


name: GSS:Mg2+ dimer synthesizes GSH (Rattus norvegicus)


name: (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + ML-236A carboxylate <=> holo-[2-methylbutanoate polyketide synthase] + mevinic carboxylate


name: Metallochaperone inserts Cu2+ into MT-CO1 (Caenorhabditis elegans)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Sus scrofa)


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Canis familiaris)


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-organyl-2-lyso-sn-glycero-3-phospholipid <=> 1-O-alkyl-sn-glycero-3-phosphocholine + a 1-organyl-2-acetyl-sn-glycero-3-phospholipid


name: Release of novel PDGFs as latent factors (Caenorhabditis elegans)


name: 2-oxobutanoate + H(+) + NADH + NH4(+) => (2S)-2-aminobutanoate + H2O + NAD(+)


name: Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Canis familiaris)


name: 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Caenorhabditis elegans)


name: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine <=> 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H(+) + S-adenosyl-L-homocysteine


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + a triacyl-sn-glycerol => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol


name: (+)-piperitol + O2 + reduced [NADPH--hemoprotein reductase] => (+)-sesamin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: acetyl-CoA + an arylamine <=> an N-acetylarylamine + CoA


name: Condensin II complex binds H4K20me1-containing nucleosomes (Gallus gallus)


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Mus musculus)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)


name: ATP + L-glutamate + putrescine = ADP + gamma-L-glutamylputrescine + H(+) + phosphate


name: JAK1 binds IL4R in IL4-bound IL4R1 (Mus musculus)


name: TFAP2C translocates to the nucleus (Sus scrofa)


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O => a 1-O-alkyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA2 (d18:1(4E)/18:0) = CMP + ganglioside GM2 (d18:1(4E)/18:0) + H(+)


name: AH2 + prostaglandin G3 => A + H2O + prostaglandin H3


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Sus scrofa)


name: 2-oxoglutarate + L-2,4-diaminobutanoate = L-aspartate 4-semialdehyde + L-glutamate


name: (2E,6E)-farnesyl diphosphate => (-)-alpha-cedrene + diphosphate


name: LRR FLII-interacting protein 1 binds dsDNA (Homo sapiens)


name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Mus musculus)


name: L-xylopyranose(out) + 2 Na(+)(out) => L-xylopyranose(in) + 2 Na(+)(in)


name: a flavonol 7-O-(6-O-malonyl-beta-D-glucoside) + CoA => a flavonol 7-O-beta-D-glucoside + malonyl-CoA


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Orexin 1 receptor can bind orexin-A neuropeptide (Homo sapiens)


name: p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)


name: Type I Na+-coupled phosphate co-transport (Bos taurus)


name: NPC2 transfers CHOL to NPC1 (Xenopus tropicalis)


name: SGTA binds Tail-anchored protein (Bos taurus)


name: 3-(2,4-dioxopentyl)-3,6,8,9-tetrahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2 = 3-(2,4-dioxopentyl)-2,3,6,8,9-pentahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Saccharomyces cerevisiae)


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Drosophila melanogaster)


name: Follitropin is a heterodimer (Rattus norvegicus)


name: a fatty acid + ethanol + H(+) => a fatty acid ethyl ester + H2O


name: 5-O-beta-D-mycaminosyltylonolide + dTDP-6-deoxy-alpha-D-allose <=> demethyllactenocin + dTDP + H(+)


name: (2R,3S)-3-isopropylmalate(in) + sulfate(out) <=> (2R,3S)-3-isopropylmalate(out) + sulfate(in)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Plasmodium falciparum)


name: n H(+)(out) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanine(out) = n H(+)(in) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanine(in)


name: H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol = a fatty acid + H(+) + long chain acyl-3-O-beta-D-galactosyl-sn-glycerol


name: CHL1 interacts with beta1 integrins (Homo sapiens)


name: a globoside Gb3Cer (d18:1(4E)) + UDP-alpha-D-galactose <=> a globoside GalGb3Cer (d18:1(4E)) + H(+) + UDP


name: G alpha (q) binds to Trio family RhoGEFs (Xenopus tropicalis)


name: Activated FGFR3 binds FRS2 (Mus musculus)


name: ATP7A transports cytosolic Cu2+ to extracellular region (Gallus gallus)


name: (2E)-geranyl diphosphate <=> diphosphate + sabinene


name: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O <=> alpha-D-ribose 1,5-bisphosphate + H(+)


name: UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Rattus norvegicus)


name: RNA polymerase II complex recruiting activity


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Homo sapiens)


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O => a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H(+)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Drosophila melanogaster)


name: an NDP-alpha-D-glucose + D-glucose = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H(+)


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H(+) + NADPH => CDP-alpha-D-abequose + NADP(+)


name: Exocytosis of azurophil granule membrane proteins (Danio rerio)


name: cholest-4-en-3-one + H(+) + NADPH => 5beta-cholestan-3-one + NADP(+)


name: Binding of ADAR1 homodimer to dsRNA duplex (Mus musculus)


name: SEC24A,B:SEC23A bind SEC22B (Dictyostelium discoideum)


name: p300 acetylates RELA subunit (Drosophila melanogaster)


name: ATP + carbamoyl phosphate + H2O + kanamycin A => 6''-O-carbamoylkanamycin A + AMP + diphosphate + H(+) + phosphate


name: ALOXE3 isomerises 12R-HpETE to HXA3 (Homo sapiens)


name: ATP + H2O + L-arginine(out) = ADP + H(+) + L-arginine(in) + phosphate


name: MCM3 binds MCM5 (Drosophila melanogaster)


name: PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Schizosaccharomyces pombe)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Sus scrofa)


name: 3,4-dihydrocoumarin + H2O => 3-(2-hydroxyphenyl)propanoate + H(+)


name: 6-deoxotyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + typhasterol


name: SUMOylation of TFAP2C with SUMO1 (Xenopus tropicalis)


name: PDE3A inhibitors bind PDE3A (Gallus gallus)


name: Initial activation of proMMP9 by MMPs (Caenorhabditis elegans)


name: Factor D cleaves C3(H2O)-bound Factor B (Bos taurus)


name: (2E)-tetradecenedioyl-CoA + H2O <=> (3S)-hydroxytetradecanedioyl-CoA


name: p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol (Mus musculus)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA


name: (R)-mandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase]


name: MBD2 binds methylcytosine in chromatin (Drosophila melanogaster)


name: 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2 => 3-hydroxyanthranilate + O2


name: 12-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 12,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Ser-[protein] + CMP-N-acetyl-beta-neuraminate <=> 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-Ser-[protein] + CMP + H(+)


name: Interaction of KIT and sSCF (Homo sapiens)


name: indole-3-pyruvate + S-adenosyl-L-methionine <=> (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + S-adenosyl-L-homocysteine


name: H(+) + hexanoyl-[ACP] + malonyl-[ACP] = 3-oxooctanoyl-[ACP] + CO2 + holo-[ACP]


name: L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] <=> H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)


name: (1R)-(1-hydroxyethyl)phosphonate + O2 = acetate + 2 H(+) + phosphate


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Canis familiaris)


name: Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region (Homo sapiens)


name: 3-oxochola-4,6-dien-24-oate + H2O => 7alpha-hydroxy-3-oxochol-4-en-24-oate


name: Membrane depolarization upon activation of Ca impermeable AMPA receptors (Mus musculus)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine


name: ergosteryl 3-beta-D-glucoside + H2O => D-glucose + ergosterol


name: CYB5A:heme reduces Asc.- to AscH- (Caenorhabditis elegans)


name: L-threitol + NAD(+) <=> H(+) + L-erythrulose + NADH


name: IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Xenopus tropicalis)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Rattus norvegicus)


name: SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Homo sapiens)


name: Production of AA by iPLA2 upon FCGR activation (Sus scrofa)


name: The Ligand:GPCR:Gi complex dissociates (Canis familiaris)


name: (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose => (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O


name: Coat Assembly (Dictyostelium discoideum)


name: CO2 + phosphoethanolamine => H(+) + O-phospho-L-serine


name: (S)-4-hydroxymandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-hydroxyphenylacetonitrile + O2 + reduced [NADPH--hemoprotein reductase]


name: Resistant ERBB2 KD mutants do not bind trastuzumab (Homo sapiens)


name: DPH6 ligates ammonium to diphthine-EEF2 (Xenopus tropicalis)


name: Cleavage of uracil by TDG glycosylase (Sus scrofa)


name: NADPH + O2 + rifampicin <=> H(+) + H2O + NADP(+) + rifampicin para-naphthoquinone carboxamide


name: PP2A dephosphorylates BANF1 (Mus musculus)


name: Aquaporins passively transport water into cells (Sus scrofa)


name: 1,2,3-trioctanoylglycerol + H2O = dioctanoylglycerol + H(+) + octanoate


name: arsenite + 2 Fe(III)-[cytochrome c] + H2O <=> arsenate + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: USP12, USP26 deubiquitinate AR (Homo sapiens)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Gallus gallus)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> 1,10-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cytidine(1920) in 23S rRNA + S-adenosyl-L-methionine => 2'-O-methylcytidine(1920) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Dictyostelium discoideum)


name: (-)-menthyl beta-D-glucoside + H(+) + UDP => (-)-menthol + UDP-alpha-D-glucose


name: 2-oxosuccinamate + H2O2 + NH4(+) => D-asparagine + H2O + O2


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Danio rerio)


name: FUK phosphorylates beta-Fuc to Fuc1P (Xenopus tropicalis)


name: a menaquinol + sulfate => a menaquinone + H2O + sulfite


name: TP53 stimulates PRDM1 expression (Homo sapiens)


name: GMPS dimer transforms 6TXMP to 6TGMP (Dictyostelium discoideum)


name: ATP + chlorophyllide a + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin] => 3-deacetyl-3-vinylbacteriochlorophyllide a + ADP + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate


name: pregnan-21-ol dehydrogenase (NAD+) activity


name: (2S)-2-amino-4-deoxychorismate + H2O => chorismate + NH4(+)


name: Translocation of DFF to the nucleus (Rattus norvegicus)


name: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H(+)


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Danio rerio)


name: Conversion of malonyl-CoA and acetyl-CoA to palmitate (Sus scrofa)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Drosophila melanogaster)


name: 3-oxo-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + CO2 + CoA => (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H(+) + malonyl-CoA


name: ADP + D-xylulose 5-phosphate + H(+) => ATP + D-xylulose


name: 2-oxopent-4-enoate + salicylate => 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O


name: (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + H(+) + NADPH = (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + NADP(+)


name: SUCLG1/A2 cleaves succinyl-CoA (Schizosaccharomyces pombe)


name: (+)-piperitol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (+)-pinoresinol + O2 + reduced [NADPH--hemoprotein reductase]


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Bos taurus)


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Canis familiaris)


name: 4-coumaroyl-CoA + H(+) + H2O + malonyl-CoA = 4-hydroxybenzalacetone + 2 CO2 + 2 CoA


name: USP47 deubiquitinates POLB (Homo sapiens)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O => 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA + H(+)


name: H2O + 2 monodehydro-L-ascorbate radical + N-decanoyl-(2S)-hydroxyglycine => 2 L-ascorbate + N-decanoylglycine + O2


name: a long-chain fatty acyl-CoA + acetyl-CoA = a long-chain 3-oxo-fatty acyl-CoA + CoA


name: O2 + phylloquinone + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein reductase]


name: NADPH + O2 + questin = demethylsulochrin + NADP(+)


name: NADP(+) + prenol => 3-methyl-2-butenal + H(+) + NADPH


name: 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + S-adenosyl-L-methionine = 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin C + H(+) + S-adenosyl-L-homocysteine


name: NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)


name: BIL binds GSTA1, FABP1 (Xenopus tropicalis)


name: Fe(II)-[cytochrome c] + 2 H(+) + nitrite => Fe(III)-[cytochrome c] + H2O + nitric oxide


name: Alpha-1-Microglobulin is cleaved (Canis familiaris)


name: L-aspartate(in) + L-leucine(out) <=> L-aspartate(out) + L-leucine(in)


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Homo sapiens)


name: H2O + sphing-4-enine-phosphocholine => H(+) + phosphocholine + sphing-4-enine


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Drosophila melanogaster)


name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Danio rerio)


name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 (Sus scrofa)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: (2E,13Z)-docosadienoyl-CoA + H2O => (3R)-hydroxy-(13Z)-docosenoyl-CoA


name: Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C (Homo sapiens)


name: H2O + N(2)-benzoyl-D-arginine-4-nitroanilide <=> 4-nitroaniline + H(+) + N(2)-benzoyl-D-arginine


name: factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Bos taurus)


name: ELOVL3 gene expression is stimulated by EBF2 and negatively regulated by ZNF423 (Homo sapiens)


name: PGG2 is reduced to PGH2 by PTGS2 (Bos taurus)


name: H(+) + NADH + sulfoacetaldehyde => 2-hydroxyethane-1-sulfonate + NAD(+)


name: (3S)-3-aminobutanoyl-CoA <=> (2E)-butenoyl-CoA + NH4(+)


name: 1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate


name: 3-hydroxypentacecilide A + A = AH2 + chrodrimanin C


name: MAPK1,(MAPK3) phosphorylates NPAS4 (Homo sapiens)


name: 16-hydroxyhexadecanoate + ATP + CoA <=> 16-hydroxyhexadecanoyl-CoA + AMP + diphosphate


name: pseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylpseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-homocysteine


name: [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + O2 = glycine betaine + 2 H(+) + phosphate


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate => an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Bos taurus)


name: uracil:monoatomic cation symporter activity


name: Activation of MT-MMPs by FURIN (Xenopus tropicalis)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Sus scrofa)


name: L-alanine(out) + L-aspartate(in) <=> L-alanine(in) + L-aspartate(out)


name: DLD dimer dehydrogenates dihydrolipoyl (Homo sapiens)


name: SREBP1A,1C,2 translocates to the nucleus (Canis familiaris)


name: RAF phosphorylates MAP2K dimer (Gallus gallus)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Mus musculus)


name: VAV exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: 2 H(+) + O2 + octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] <=> (9Z)-octadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: diphosphate + hexadecanoyl-AMP => ATP + H(+) + hexadecanoate


name: GSTZ1 isomerizes 4-MAA (Canis familiaris)


name: (R)-carnitine + 2-methylbutanoyl-CoA <=> CoA + O-2-methylbutanoyl-(R)-carnitine


name: (2E,6E)-farnesyl diphosphate + H(+) + NADPH + O2 <=> (2E,6E)-omega-hydroxy-farnesyl diphosphate + H2O + NADP(+)


name: KCNJ11:ABCC9 binds nicorandil (Drosophila melanogaster)


name: SLC6A4 binds TCAs and SSRIs (Mus musculus)


name: Ubiquitinated Cdc6 is degraded by the proteasome (Bos taurus)


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Gallus gallus)


name: Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions (Rattus norvegicus)


name: VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Caenorhabditis elegans)


name: H(+)(out) + L-leucyl-L-proline(out) => H(+)(in) + L-leucyl-L-proline(in)


name: eburicol + S-adenosyl-L-methionine = (24Z)-ethylidenelanosterol + H(+) + S-adenosyl-L-homocysteine


name: 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(beta-D-glucuronate)


name: Parkin binds Ub:UBE2N:UBE2V1 (Danio rerio)


name: GTP + 2 H2O = GMP + 2 H(+) + 2 phosphate


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Homo sapiens)