name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Caenorhabditis elegans)


name: a menaquinol + 2 H(+)(in) + nitrate = a menaquinone + 2 H(+)(out) + H2O + nitrite


name: ABHD4 hydrolyses NAPE (Canis familiaris)


name: Clathrin internalises EPH:EFN complexes (Drosophila melanogaster)


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Mus musculus)


name: cyclohexanone + H2O2 + NH4(+) => cyclohexylamine + H2O + O2


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Rattus norvegicus)


name: ALDH2 transforms GTN to NO (Drosophila melanogaster)


name: 4-O-beta-D-glucosyl-trans-ferulate + H2O => 4-O-beta-D-glucosyl-vanillin + acetate


name: L-valine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (E)-2-methylpropanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 17-O-acetylnorajmaline + NADP(+) = (2R)-1,2-dihydrovomilenine + 2 H(+) + NADPH


name: an N-fatty-acyl-L-alpha-amino acid + H2O <=> a fatty acid + an L-alpha-amino acid


name: Translocation of YAP1 to the nucleus (Gallus gallus)


name: Na(+)(out) + uracil(out) => Na(+)(in) + uracil(in)


name: (R)-carnitine + octanoyl-CoA => CoA + O-octanoyl-(R)-carnitine


name: DARC  is a non-specific receptor for many chemokines (Homo sapiens)


name: chenodeoxycholate + octyl beta-D-glucose = beta-D-glucosyl-(1->3)-O-chenodeoxycholate + octan-1-ol


name: Ubiquitination of phospho-p27/p21 (Caenorhabditis elegans)


name: 2-oxoglutarate + decanoyl-CoA + O2 <=> 2-hydroxydecanoyl-CoA + CO2 + succinate


name: RHOD binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: p-Y705,S727 STAT3 dimer binds NOTCH gene (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + 1-hexadecanoylglycerone 3-phosphate = 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate


name: NAAA hydrolyses NAEs to FAs and ethanolamine (Caenorhabditis elegans)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Canis familiaris)


name: ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate <=> AMP + diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate


name: a 1-acylglycerol + an acyl-CoA <=> a 1,3-diacylglycerol + CoA


name: TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (Gallus gallus)


name: a long-chain fatty acid + ATP + holo-[ACP] <=> a long-chain fatty acyl-[ACP] + AMP + diphosphate


name: NTP Binds Active Site of RNA Polymerase II (Mus musculus)


name: SLC2A9 transports Fru, Glc, urate (Rattus norvegicus)


name: a methylated secondary amine + H(+) + S-adenosyl-L-homocysteine => a secondary amine + S-adenosyl-L-methionine


name: a fatty acid(in) + ATP + H2O <=> a fatty acid(out) + ADP + H(+) + phosphate


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Rattus norvegicus)


name: Interaction of NCAM1 with collagens (Homo sapiens)


name: USP17L2 deubiquitinates RCE1 (Bos taurus)


name: USP48 cleaves polyubiquitin (Canis familiaris)


name: a quinone + succinate => a quinol + fumarate


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: COMT transfers Met to DOPAC to form HVA (Schizosaccharomyces pombe)


name: nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Homo sapiens)


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Sus scrofa)


name: 10-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Sus scrofa)


name: 3-alpha(S)-strictosidine + H2O = D-glucose + strictosidine aglycone


name: (3R)-hydroxyeicosanoyl-CoA + NAD(+) => 3-oxoeicosanoyl-CoA + H(+) + NADH


name: SLC6A4 binds TCAs and SSRIs (Gallus gallus)


name: D-glucose + phosphate => D-glucose 6-phosphate + H2O


name: ATP2B4 binds to NOS1, inhibiting it (Homo sapiens)


name: a very long-chain fatty acyl-CoA + H2O <=> a very long-chain fatty acid + CoA + H(+)


name: H(+) + NAD(+) + 2 reduced [cytochrome P450] => NADH + 2 oxidized [cytochrome P450]


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Rattus norvegicus)


name: PTK6 phosphorylates DOK1 (Rattus norvegicus)


name: estrone + PAPS => estrone 3-sulfate + PAP (Danio rerio)


name: TRAF6 binds MALT1 oligomers (Rattus norvegicus)


name: B4GALTs transfer Gal to the N-glycan precursor (Mus musculus)


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Danio rerio)


name: acetaldehyde + H2O + NAD(+) <=> acetate + 2 H(+) + NADH


name: a D-hexose + H(+) + phosphoramidate = alpha-D-hexose 1-phosphate + NH4(+)


name: 5-methyluridine(54) in tRNA + [TtuB sulfur-carrier protein]-Gly-NH-CH2-C(O)SH + ATP + H2O = 5-methyl-2-thiouridine(54) in tRNA + [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + AMP + diphosphate + 2 H(+)


name: L-asparagine + pyruvate = 2-oxosuccinamate + L-alanine


name: POU5F1 (OCT4), SOX2, NANOG bind the TDGF1 promoter (Homo sapiens)


name: 1D-myo-inositol 2-phosphate + H2O => myo-inositol + phosphate


name: (S)-cheilanthifoline + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-stylopine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Rattus norvegicus)


name: (R,2E)-alpha-cericerene + diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: Change of PKC theta conformation (Rattus norvegicus)


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Canis familiaris)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Drosophila melanogaster)


name: (R)-mandelate + NAD(+) <=> H(+) + NADH + phenylglyoxylate


name: Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Bos taurus)


name: AMP + diphosphate + nonanoyl-CoA => ATP + CoA + nonanoate


name: HSF1-mediated gene expression (Dictyostelium discoideum)


name: FAR1 reduces PalmCoA to HXOL (Bos taurus)


name: MAP2Ks and MAPKs bind to the activated RAF complex (Mus musculus)


name: L-threonyl-[peptidyl-carrier protein] + salicyl-[ACP] <=> H(+) + H2O + holo-[ACP] + salicylmethyloxazolinyl-[peptidyl-carrier protein]


name: a 5'-end triphospho-adenosine in mRNA + H2O = a 5'-end diphospho-adenosine in mRNA + H(+) + phosphate


name: 9,10-epoxy-(12Z)-octadecenoate + H2O => 9,10-dihydroxy-(12Z)-octadecenoate


name: YKI transports from the cytosol to the nucleus (Drosophila melanogaster)


name: IGF1R phosphorylates SHC1 (Homo sapiens)


name: Formation of the 'destruction complex' (Drosophila melanogaster)


name: dihydropyrimidine dehydrogenase (NADP+) activity


name: Dopachrome is transformed to DHICA by DCT (Sus scrofa)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Plasmodium falciparum)


name: H2O + methylglyoxal => (R)-lactate + H(+)


name: GGT dimers hydrolyse GSH (Saccharomyces cerevisiae)


name: KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Sus scrofa)


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Dictyostelium discoideum)


name: BMP2 binds to the receptor complex (Caenorhabditis elegans)


name: Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Bos taurus)


name: RHOD:GTP recruits DAIPH2-3 to endosomes (Bos taurus)


name: (1R,4R)-camphor + H(+) + NADPH + O2 => (+)-6-exo-hydroxycamphor + H2O + NADP(+)


name: Hemoglobin A binds O2, releasing H+ and CO2 (Gallus gallus)


name: acetyl-CoA + L-lysyl-[alpha-tubulin] => CoA + H(+) + N(6)-acetyl-L-lysyl-[alpha-tubulin]


name: acetyl-CoA + H(+) + malonyl-CoA <=> acetoacetyl-CoA + CO2 + CoA


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Homo sapiens)


name: 3-hydroxyphenylpropionic acid transmembrane transporter activity


name: FGF2:TGFBR3 binding to GIPC1 (Danio rerio)


name: 2'-deoxyinosine(in) + H(+)(in) => 2'-deoxyinosine(out) + H(+)(out)


name: a dolichyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol + H(+) => a dolichyl beta-D-mannosyl phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol


name: 2-oxoglutarate + 3-methylhexadecanoyl-CoA + O2 = 2-hydroxy-3-methylhexadecanoyl-CoA + CO2 + succinate


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Caenorhabditis elegans)


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Xenopus tropicalis)


name: (9S,10R)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 18-hydroxy-(9S,10R)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active MTORC1 phosphorylates ULK1 (Rattus norvegicus)


name: albonoursin + H2O2 => cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2


name: 3'-dephospho-CoA(in) + ADP(out) = 3'-dephospho-CoA(out) + ADP(in)


name: CoA + zymosterol ester => an acyl-CoA + zymosterol


name: laricitrin + S-adenosyl-L-methionine = 3,3'-O-dimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: H2O + N-acetyl-D-galactosamine + O2 => H(+) + H2O2 + N-acetyl-D-galactosaminate


name: CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O


name: 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O <=> (9Z)-octadecenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H(+)


name: ECE2 cleaves EDN1(53-90) (Canis familiaris)


name: 17beta-estradiol + 3'-phosphoadenylyl sulfate => 17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Gallus gallus)


name: Importin-8 imports AGO2:miRNA into the nucleus (Schizosaccharomyces pombe)


name: Histone acetyltransferases are recruited to the TFF1 gene (Saccharomyces cerevisiae)


name: ATP + glutathione + glutathionylspermidine => ADP + H(+) + phosphate + trypanothione


name: botC LC cleaves target cell SNAP25 (Homo sapiens)


name: NMRK1 phosphorylates NAR to yield NAMN (Bos taurus)


name: KALRN exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)


name: Defective SLC37A4 does not exchange G6P and Pi across the ER membrane (Homo sapiens)


name: EP400 binds CDKN1A promoter (Mus musculus)


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Bos taurus)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Xenopus tropicalis)


name: DVL1 is ubiquitinated by HECW1 (Mus musculus)


name: CMP-N-acetyl-beta-neuraminate + N-acetyl-beta-lactosamine => CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine


name: DVL2 is phosphorylated by PKC (Canis familiaris)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Sus scrofa)


name: 2 formate + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 2 CO2 + H(+) + NADH + 2 reduced [2Fe-2S]-[ferredoxin]


name: a fatty acyl-[ACP] + sn-glycerol 3-phosphate <=> a 1-acyl-sn-glycero-3-phosphate + holo-[ACP]


name: Tyrosine phosphorylation of CRMPs by Fes (Homo sapiens)


name: Trans-autophosphorylation of ERBB2 heterodimers (Gallus gallus)


name: CoA + H(+) + N-(9Z-octadecanoyl)-dopamine => (9Z)-octadecenoyl-CoA + dopamine


name: alpha-D-Tyv-(1->3)-alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+) => alpha-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-3,6-dideoxy-alpha-D-mannose


name: Cleavage and polyadenylation of Intronless Pre-mRNA (Caenorhabditis elegans)


name: 5-methylcytidine(34) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine => cytidine(34) in tRNA precursor + S-adenosyl-L-methionine


name: Release of 40S and 60S subunits from the 80S ribosome  (Caenorhabditis elegans)


name: 6-acetamido-2-oxohexanoate + H2O + NAD(+) => 5-acetamidopentanoate + CO2 + H(+) + NADH


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Mus musculus)


name: 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH => 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NADP(+)


name: KIT mutants bind GRB2-SOS (Homo sapiens)


name: 2-aminophenoxazin-3-one + AH2 + 2 H2O => 2 2-aminophenol + A + O2


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)


name: FAM20C phosphorylates FAM20C substrates (Mus musculus)


name: B4GALT5/6 transfer Gal to GlcCer (Danio rerio)


name: ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Mus musculus)


name: PVR:PVRL3 trans heterodimer interaction (Mus musculus)


name: acetyl-CoA + H(+) + malonyl-[ACP] <=> 3-oxobutanoyl-[ACP] + CO2 + CoA


name: glycine + H(+) + NADH + pyruvate => H2O + N-(carboxymethyl)-D-alanine + NAD(+)


name: TRPV1 binds TRPV1 blockers (Rattus norvegicus)


name: isoxazolin-5-one + O-acetyl-L-serine => 3-(5-oxoisoxazolin-2-yl)-L-alanine + acetate + H(+)


name: Transhomodimerization of Nectin-like (Necl) proteins (Bos taurus)


name: "gellan tetrasaccharide unsaturated glucuronosyl hydrolase"


name: ciliary neurotrophic factor receptor activity


name: OCT1 transports organic cations into hepatic cells (Rattus norvegicus)


name: STAT3 binds activated MET receptor (Mus musculus)


name: Caspase 3-mediated cleavage of DFF45 (117) (Sus scrofa)


name: corticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 18-hydroxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: 2-hydroxy-4-methoxybenzoate + A + N2 => AH2 + cremeomycin


name: 2 H(+)(in) + L-glutamate(in) => 2 H(+)(out) + L-glutamate(out)


name: a dipeptide(out) + H(+)(out) = a dipeptide(in) + H(+)(in)


name: D-galactose(in) + H(+)(in) => D-galactose(out) + H(+)(out)


name: SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Danio rerio)


name: ACLY tetramer binds ETC-1002-CoA (Schizosaccharomyces pombe)


name: ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Sus scrofa)


name: (9Z)-octadecenoate + glycerol + H(+) => 1-(9Z-octadecenoyl)-glycerol + H2O


name: Hydrolysis of GTP and dissociation of 28S and 39S subunits (Homo sapiens)


name: 3-oxochol-4,6-dien-24-oyl-CoA + H2O => 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA


name: BCKDK phosphorylates BCKDH (Canis familiaris)


name: eNOS:Caveolin-1 complex binds to CaM (Mus musculus)


name: Activation of linoleic acid to linoleoyl-CoA (Dictyostelium discoideum)


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Canis familiaris)


name: (S)-malate + NAD(+) <=> H(+) + NADH + oxaloacetate


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Canis familiaris)


name: (20S)-ginsenoside Rb1 + H(+) + UDP => (20S)-ginsenoside Rd + UDP-alpha-D-glucose


name: 2 H(+) + NADH + propynoate => H2O + NAD(+) + prop-2-ynal


name: a 2-oxocarboxylate + AH2 => A + a (2R)-2-hydroxycarboxylate


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 2-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + O2 => (S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-1,3-oxazole-[protein] + H2O2


name: Activation of linoleic acid to linoleoyl-CoA (Danio rerio)


name: an aliphatic alcohol + H(+) + tetradecanoate => a tetradecanoate ester + H2O


name: GPLD1 hydrolyses GPI-anchors from proteins (Sus scrofa)


name: 2 (4Z,15Z)-bilirubin IXalpha + O2 => 2 biliverdin IXalpha + 2 H2O


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Sus scrofa)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Caenorhabditis elegans)


name: D-gluconate + H(+) => D-glucono-1,5-lactone + H2O


name: 17beta-estradiol + NADP(+) <=> estrone + H(+) + NADPH


name: CD320-mediated TCN2:RCbl uptake and delivery to lysosome (Bos taurus)


name: 1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O => 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide


name: (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + 6 CO2 + 6 CoA + 4 H2O + NAD(+) + 5 NADP(+) => 12 H(+) + 6 malonyl-CoA + NADH + 5 NADPH


name: 3-oxohexacosanoyl-CoA + H(+) + NADH <=> (3R)-hydroxyhexacosanoyl-CoA + NAD(+)


name: acetyl-CoA + tetradecanoyl-CoA => 3-oxohexadecanoyl-CoA + CoA


name: Fillagrin and keratin intermediate filaments polymerize forming a network (Sus scrofa)


name: THEM86B hydrolyses PMCHO, PMETAM (Rattus norvegicus)


name: dichlorochromopyrrolate + H(+) + NH4(+) => 7-chloroindole-3-pyruvate imine dimer


name: ZEB2 binds SP1 (Drosophila melanogaster)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII (Caenorhabditis elegans)


name: dihydrozeatin + NADP(+) => H(+) + NADPH + zeatin


name: a (3R)-3-isocyanyl-fatty acid + ATP + holo-[ACP] => a (3R)-3-isocyanyl-fatty acyl-[ACP] + AMP + diphosphate


name: NOTCH3-ligand complex is cleaved to produce NEXT3 (Rattus norvegicus)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Caenorhabditis elegans)


name: DDHD1,2 hydrolyse PA (Plasmodium falciparum)


name: 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n) => H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline


name: Caspase-mediated cleavage of Z0-2 (Caenorhabditis elegans)


name: LEAP2 binds bacteria (Rattus norvegicus)


name: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose => 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose + H(+)


name: JAK3 binds JAK3 inhibitors (Mus musculus)


name: Formation of lysino-5-ketonorleucine cross-links (Homo sapiens)


name: P2X7 mediates membrane pores that include pannexin-1 (Canis familiaris)


name: 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate


name: dibenzothiophene 5-oxide + FMN + H(+) + H2O => dibenzothiophene + FMNH2 + O2


name: (S)-2-amino-6-oxohexanoate + H2O + NADP(+) = 2 H(+) + L-2-aminoadipate + NADPH


name: MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)


name: 3-hydroxyhispidin + O2 => 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one


name: guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Homo sapiens)


name: DBT transfers BCAA to CoA (Plasmodium falciparum)


name: diphosphate + pppA(2'-5')pG => ATP + GTP


name: 4-phospho-D-erythronate + NAD(+) <=> (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + H(+) + NADH


name: histone arginine N-methyltransferase activity


name: a globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside Gb4Cer (d18:1(4E)) + H(+) + UDP


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Xenopus tropicalis)


name: Insulin receptor de-phosphorylation (Mus musculus)


name: a D-glucoside + 2 Fe(III)-[cytochrome c] => a 3-dehydro-D-glucoside + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: AMP + diphosphate + diphthamide-[translation elongation factor 2] + H(+) => ATP + diphthine-[translation elongation factor 2] + NH4(+)


name: H(+) + kanamycin D + UDP => 2'-deamino-2'-hydroxyneamine + UDP-alpha-D-glucose


name: CANX dissociates from IL27:EBI3 (Mus musculus)


name: Activated FGFR2 phosphorylates PPTN11 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + a monoacyl-sn-glycero-3-phosphocholine + H(+)


name: (2E,6E)-farnesyl diphosphate <=> beta-bisabolene + diphosphate


name: CDP-DAG is converted to PGP by PGS1 (Homo sapiens)


name: biotin transmembrane transporter activity


name: 4-aminobutanoate + ATP + L-histidine = ADP + H(+) + L-homocarnosine + phosphate


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + glycyl-tRNA(Gly) => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-Gly)-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + tRNA(Gly)


name: ATP + histamine + L-glutamate = ADP + H(+) + N(alpha)-gamma-L-glutamylhistamine + phosphate


name: UPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP (Drosophila melanogaster)


name: ATP + L-tryptophan + tRNA(Trp) <=> AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)


name: 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA => (9Z,12Z)-octadecadienoyl-CoA + 2-(9Z-octadecenoyl)-glycerol


name: G-beta:G-gamma inhibits Adenylate cyclase (Canis familiaris)


name: a ribonucleoside 5'-diphosphate + GTP = a ribonucleoside 5'-triphosphate + GDP


name: kainate receptor binds glutamate (Homo sapiens)


name: The Immunoglobulin of the BCR binds antigen (Mus musculus)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: ATP + N-hexanoyl-(4R)-hydroxysphinganine => ADP + H(+) + N-hexanoyl-(4R)-hydroxysphinganine-1-phosphate


name: AKT phosphorylates KAT6A (Drosophila melanogaster)


name: SPRED dimer binds NF1 (Dictyostelium discoideum)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Homo sapiens)


name: CLCN4/5/6 exchange Cl- for H+ (Rattus norvegicus)


name: an S-substituted L-cysteine + H2O => a thiol + NH4(+) + pyruvate


name: H2O + NADP(+) + testololactone => androst-4-ene-3,17-dione + H(+) + NADPH + O2


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Bos taurus)


name: D-mannonate + NAD(+) <=> D-mannuronate + H(+) + NADH


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Sus scrofa)


name: a carboxylate + glycerol + H(+) => a 2-acylglycerol + H2O


name: (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-glycerol + H(+) => 1,2-di-(9Z-octadecenoyl)-glycerol + H2O


name: Receptors CXCR4 and 7 bind CXCL12 ligand (Gallus gallus)


name: Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Homo sapiens)


name: Bombesin-like receptors bind bombesin homologues (Canis familiaris)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Bos taurus)


name: p-S407,Y641-STAT6 is dimerized (Xenopus tropicalis)


name: Receptor CXCR6 binds CXCL16 ligand (Mus musculus)


name: SLC5A6 transports vitamins from extracellular region to cytosol (Gallus gallus)


name: Constitutive phosphorylation by GSK3 (Caenorhabditis elegans)


name: a ganglioside GM1 + GDP-beta-L-fucose => a ganglioside Fuc-GM1 + GDP + H(+)


name: ADP + H(+) + L-alanyl-L-glutamine(in) + phosphate => ATP + H2O + L-alanyl-L-glutamine(out)


name: H(+)(in) + K(+)(in) + Na(+)(out) + serotonin(out) <=> H(+)(out) + K(+)(out) + Na(+)(in) + serotonin(in)


name: 2-oxoglutarate + an alkane-alpha,omega-diamine = an omega-aminoaldehyde + L-glutamate


name: EPCAM binds itself to form homotypic cell adhesion (Homo sapiens)


name: dimethylallyl diphosphate + quinolinone B = diphosphate + peniprequinolone


name: H2O + L-arginine + O2 <=> 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: (S)-2-amino-6-oxohexanoate + H(+) + NADH + NH4(+) => H2O + L-lysine + NAD(+)


name: STAB1 (FEEL-1) binds ligands (Rattus norvegicus)


name: ambiguine A + diphosphate => dimethylallyl diphosphate + hapalindole G


name: 2-hydroxydodecanoate + H2O2 <=> 2,3-dihydroxydodecanoate + H2O


name: CLPXP binds mitochondrial matrix proteins (Caenorhabditis elegans)


name: GIP receptor binds gastric inhibitory peptide (Sus scrofa)


name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Mus musculus)


name: 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-2,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Rattus norvegicus)


name: Parathyroid hormone receptor can bind parathyroid hormone (Xenopus tropicalis)


name: Inactive G alpha (i) reassociates with G beta:gamma (Drosophila melanogaster)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Rattus norvegicus)


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Homo sapiens)


name: L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: 3,3',5-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3,3',5-triiodo-L-thyronine


name: SMAD2/3:SMAD4 heterotrimer binds SP1 (Homo sapiens)


name: Pol II elongation complex moves on the template as transcript elongates (Caenorhabditis elegans)


name: SUMOylation of TOPORS with SUMO1 (Homo sapiens)


name: Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Canis familiaris)


name: (R)-3-hydroxybutanoate(out) + H(+)(out) = (R)-3-hydroxybutanoate(in) + H(+)(in)


name: H2O + N(6)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2 = (1-deoxy-D-fructos-1-yl)amine + (S)-2-amino-6-oxohexanoate + H2O2


name: 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine => 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H2O <=> a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + D-galactose


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Canis familiaris)


name: N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: Formation of HIF:CBP:p300 complex at promoters (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + CoA + propanoate <=> AMP + diphosphate + propanoyl-CoA


name: (R)-carnitine + dodecanoyl-CoA = CoA + O-dodecanoyl-R-carnitine


name: 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + diphosphate => 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + dimethylallyl diphosphate


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+) => 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycerol <=> 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Danio rerio)


name: Activation of Ca permeable AMPA receptors (Rattus norvegicus)


name: TP53 stimulates CASP10 expression (Homo sapiens)


name: L-histidine(out) + L-phenylalanine(in) => L-histidine(in) + L-phenylalanine(out)


name: Autophosphorylation of PAK1 (Dictyostelium discoideum)


name: Activation of JAK kinases (Gallus gallus)


name: acetylcholine(in) + 2 H(+)(out) => acetylcholine(out) + 2 H(+)(in)


name: Defective NTHL1 truncation mutants do not bind cytosine glycol (Cg) (Homo sapiens)


name: BTRC binds p-S344, 347 NFE2L2 (Mus musculus)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Homo sapiens)


name: adenosine + O2 => 5'-dehydroadenosine + H2O2


name: Fusion of ERC and phagosome (Mus musculus)


name: Phosphorylation of IRS (Canis familiaris)


name: ERBB4s80:TAB2:NCOR1 complex binds S100B gene promoter (Homo sapiens)


name: dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] => 1,5-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ASC binds Caspase-8 complex (Canis familiaris)


name: H2O + N-(tetracosanoyl)-sphing-4-enine-1-phosphocholine = H(+) + N-tetracosanoyl-sphing-4-enine + phosphocholine


name: S-adenosyl-L-methionine + uridine(2634) in 25S rRNA => H(+) + N(3)-methyluridine(2634) in 25S rRNA + S-adenosyl-L-homocysteine


name: NRXNs bind NLGNs (Drosophila melanogaster)


name: Corticosteroids bind to CBG in blood (Mus musculus)


name: H2O + octadecanoyl-CoA <=> CoA + H(+) + octadecanoate


name: Alkalization of the phagosomal lumen by NOX2 (Xenopus tropicalis)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Xenopus tropicalis)


name: PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Rattus norvegicus)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Xenopus tropicalis)


name: (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + NADPH => (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + NADP(+)


name: a ganglioside GalGal-GD1b + H(+) + UDP => a ganglioside Gal-GD1b + UDP-alpha-D-galactose


name: ATP + biotin + H(+) = biotinyl-5'-AMP + diphosphate


name: a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Dictyostelium discoideum)


name: Degradation of TGF-beta receptor complex (Rattus norvegicus)


name: LARG activation by G alpha 12/13 (Gallus gallus)


name: (R)-glycerate + NADP(+) <=> 2-hydroxy-3-oxopropanoate + H(+) + NADPH


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Homo sapiens)


name: NDST1-4 N-deacetylates GlcNAc residues in heparan (Danio rerio)


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Sus scrofa)


name: ADP + glutathione(out) + glycoursodeoxycholate(out) + H(+) + phosphate => ATP + glutathione(in) + glycoursodeoxycholate(in) + H2O


name: a ganglioside GA2 (d18:1(4E)) + H2O => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetyl-beta-D-galactosamine


name: ATP + H(+) + IC-asc-C9 => diphosphate + IC-asc-C9-AMP


name: archaeosine(15) in tRNA + L-glutamate => 7-cyano-7-carbaguanosine(15) in tRNA + H2O + L-glutamine


name: 3-oxo-(9Z-octadecenoyl)-CoA + CoA => (7Z)-hexadecenoyl-CoA + acetyl-CoA


name: a 5'-end 5'-phospho-ribonucleoside-RNA + ADP + H(+) => a 5'-end dephospho-ribonucleoside-RNA + ATP


name: 2-phenylacetaldehyde + H2O + NAD(+) = 2-phenylacetate + 2 H(+) + NADH


name: 1-beta-D-galactosyl-dodecanoyl-sn-glycerol + dodecanoate + H(+) => 1-beta-D-galactosyl-2,3-didodecanoyl-sn-glycerol + H2O


name: a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate => a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O


name: 8,20-dihydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 8-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: VWF multimer binds to collagen type I (Canis familiaris)


name: 7,8-dihydroneopterin 3'-triphosphate => 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate


name: 10-deacetyltaxuyunnanin C + acetyl-CoA => CoA + taxuyunnanin C


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Sus scrofa)


name: (R)-benzoin + NADP(+) <=> benzil + H(+) + NADPH


name: (E)-non-2-enal + H2O + NAD(+) => (E)-non-2-enoate + 2 H(+) + NADH


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Gallus gallus)


name: 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + AH2 + O2 = A + H2O + N(6)-[(2E)-4-hydroxy-3-methylbut-2-en-1-yl]-2-(methylsulfanyl)adenosine(37) in tRNA


name: Fucosylation of Pre-NOTCH by POFUT1 (Homo sapiens)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: MIB2 ubiquitinates CYLD at K338, K530 (Drosophila melanogaster)


name: 2',3'-cyclophospho-GMP + H2O <=> 3'-GMP + H(+)


name: Calmodulin-bound CaMKII-gamma enters the nucleus (Homo sapiens)


name: IL4:IL4R:JAK2 binds IL13RA1:TYK2 (Mus musculus)


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Plasmodium falciparum)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Bos taurus)


name: hexadecanoyl-[ACP] + phosphate <=> hexadecanoyl phosphate + holo-[ACP]


name: 3'-phosphoadenylyl sulfate + lithocholate <=> adenosine 3',5'-bisphosphate + H(+) + lithocholate sulfate


name: Phosphorylated Cdc6 is exported from the nucleus (Canis familiaris)


name: (S)-lactate + NAD(+) = H(+) + NADH + pyruvate


name: Cis-heterodimerization of L1 and DM-GRASP/ALCAM/BEN (Homo sapiens)


name: 2 an L-alpha-amino acid => an L-aminoacyl-L-amino acid + H2O


name: (2E)-geranyl diphosphate + 7 isopentenyl diphosphate => all-trans-nonaprenyl diphosphate + 7 diphosphate


name: TLR processing at low pH (Rattus norvegicus)


name: Prolactin receptor ligands bind the prolactin receptor (Rattus norvegicus)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Gallus gallus)


name: 3-phenylpropanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4 CO2 + 4 CoA + dihydropinosylvin


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPC (Sus scrofa)


name: cytochalasin Z16 + H2O + NADP(+) => H(+) + iso-precytochalasin + NADPH + O2


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Gallus gallus)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Canis familiaris)


name: L-histidocholate + taurine => L-histidine + taurocholate


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+) => (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein]


name: GUSB tetramer hydrolyses CS/HS precursor (Xenopus tropicalis)


name: Binding of SHC1 to insulin receptor (Canis familiaris)


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Dictyostelium discoideum)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Mus musculus)


name: L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => 2 H(+) + H2O + N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: ADP + H(+) + L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) => ADP-L-glycero-beta-D-manno-heptose + L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: H2O + L-dehydroascorbate <=> 2,3-dioxo-L-gulonate


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O <=> 2-(9Z-octadecenoyl)-glycerol + H(+) + octadecanoate


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Gallus gallus)


name: PDCL binds G-protein beta and TRiC/CCT (Drosophila melanogaster)


name: L-valine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-2-methylpropanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Auto-ubiquitination of TRAF6 (Homo sapiens)


name: Pol II elongation complex moves on the template as transcript elongates (Sus scrofa)


name: 1-(9Z-octadecenoyl)-3-hexadecanoylglycerol + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoylglycerol


name: LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)


name: Translocation of Cdc25B to the cytoplasm (Rattus norvegicus)


name: OPLAH hydrolyses OPRO to L-Glu (Caenorhabditis elegans)


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Rattus norvegicus)


name: adenosine(in) + Na(+)(in) => adenosine(out) + Na(+)(out)


name: RAS GAPs stimulate RAS GTPase activity (Sus scrofa)


name: (2R)-3-phosphoglycerate + GDP-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)


name: (E)-4-coumarate + H(+) <=> 4-hydroxystyrene + CO2


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Caenorhabditis elegans)


name: (+)-lariciresinol + H(+) + NADPH => (-)-secoisolariciresinol + NADP(+)


name: IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Mus musculus)


name: D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Canis familiaris)


name: CREBBP acetylates HINT1 dimer (Bos taurus)


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Homo sapiens)


name: GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose => a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)


name: luteolin 7-O-beta-D-glucuronide + UDP-alpha-D-glucuronate => H(+) + luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] + UDP


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + serotonin <=> CoA + H(+) + N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin


name: beta-D-gentiobiosyl crocetin + UDP-alpha-D-glucose => beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NAD(+) = 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Drosophila melanogaster)


name: ATP + L-serine = ADP + H(+) + O-phospho-L-serine


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Homo sapiens)


name: DCP1-DCP2 complex decaps mRNA (Bos taurus)


name: Excess cysteine yields lanthionine and H2S (Saccharomyces cerevisiae)


name: alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 H(+) + 2 UDP


name: H(+)(out) + L-lysine(out) = H(+)(in) + L-lysine(in)


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Sus scrofa)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: CO2 + 2 H2O + heme b => H(+) + H2O2 + harderoheme III


name: (6R)-10-formyltetrahydrofolate + H2O + NADP(+) <=> (6S)-5,6,7,8-tetrahydrofolate + CO2 + H(+) + NADPH


name: beta-alanyl-L-ornithine + H2O => beta-alanine + L-ornithine


name: AMP + ATP <=> ADP + ADP [AK2] (Drosophila melanogaster)


name: ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Mus musculus)


name: ATP + firefly D-luciferin + O2 <=> AMP + CO2 + diphosphate + firefly oxyluciferin + hnu


name: Carbonic anhydrase hydrates carbon dioxide (cytosol) (Plasmodium falciparum)


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Xenopus tropicalis)


name: Degradation of multiubiquitinated Cdh1 (Gallus gallus)


name: CDK1:CCNB phosphorylates NEK9 (Rattus norvegicus)


name: 3-oxosphinganine + tetradecanoyl-CoA <=> CoA + H(+) + N-tetradecanoyl-3-oxosphinganine


name: Recruitment of SYK to p-DAP12 (Rattus norvegicus)


name: Caspase-mediated cleavage of MST3 (Sus scrofa)


name: Collagen type II degradation by MMP15 (Caenorhabditis elegans)


name: protein-containing complex stabilizing activity


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + succinate


name: a menaquinone + 5 H(+)(in) + NADH <=> a menaquinol + 4 H(+)(out) + NAD(+)


name: anthraniloyl-CoA + 2 H(+) + 2 NADPH + O2 <=> 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + H2O + 2 NADP(+)


name: N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Homo sapiens)


name: MSH2:MSH6 exchanges ADP for ATP (Canis familiaris)


name: flavanone 7-O-beta-D-glucoside + UDP-beta-L-rhamnose => flavanone 7-O-[alpha-L-rhamnosyl-(1->2)-beta-D-glucoside] + H(+) + UDP


name: CDK2:CCNA phosphorylates TERF2 (Homo sapiens)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O => (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: formyl-CoA + oxalate = formate + oxalyl-CoA


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Canis familiaris)


name: ABC-type phytochelatin transporter activity


name: PKC-delta translocates to plasma membrane (Saccharomyces cerevisiae)


name: Sialic acid binds SIGLEC (Xenopus tropicalis)


name: H(+) + NADH + 2 NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] => NAD(+) + 2 NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: DAG is acylated to TAG by DGAT1/2 (Caenorhabditis elegans)


name: hexadecanoyl-CoA + sn-glycerol 3-phosphate = 1-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Caenorhabditis elegans)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Mus musculus)


name: JMJD6 demethylates MeR3-histone H3 (Homo sapiens)


name: N,N-dimethylaniline N-oxide => formaldehyde + N-methylaniline


name: EP300,CREBBP bind SOH-C481-FOXO4 (Homo sapiens)


name: Recognition of AAUAAA sequence by CPSF (Schizosaccharomyces pombe)


name: 6-O-malonyl-rhaponticin + CoA => malonyl-CoA + rhaponticin


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Xenopus tropicalis)


name: (15S)-hydroxy-(11Z,13E)-eicosadienoate + glutathione disulfide + H2O => (15S)-hydroperoxy-(11Z,13E)-eicosadienoate + 2 glutathione


name: phosphoenolpyruvate + H2O <=> 2-phosphoglycerate (Gallus gallus)


name: abscisate(out) + ATP + H2O => abscisate(in) + ADP + H(+) + phosphate


name: Chromokinesins form dimers (Drosophila melanogaster)


name: CCND1 binds RUNX3 and displaces EP300 (Homo sapiens)


name: PTPN7 binds p-T,Y-MAPK (Saccharomyces cerevisiae)


name: JAK2 Phosphorylates IRS in Response to Leptin (Homo sapiens)


name: H2O + N-tetradecanoylethanolamine => ethanolamine + tetradecanoate


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Sus scrofa)


name: Activation of TWIK-related K+ channel (TREK) (Sus scrofa)


name: ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Plasmodium falciparum)


name: tRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent


name: ALOX5 oxidises DHA to 7-HDHA (Mus musculus)


name: (S)-beta-macrocarpene + O2 + reduced [NADPH--hemoprotein reductase] <=> [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-xylose + NADP(+) <=> D-xylono-1,5-lactone + H(+) + NADPH


name: Gastrin binds to CCK-B receptor (Homo sapiens)


name: Formation of the MCC complex (Saccharomyces cerevisiae)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Sus scrofa)


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Canis familiaris)


name: BTRC binds p-S344, 347 NFE2L2 (Canis familiaris)


name: SRD5A3 reduces pPNOL to DCHOL (Gallus gallus)


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Rattus norvegicus)


name: CO2 + decanal + H(+) + succinate + sulfate => 2-oxoglutarate + decyl sulfate + O2


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Caenorhabditis elegans)


name: SPP1 (osteopontin) binds CD44 (Gallus gallus)


name: GDP-alpha-D-rhamnose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate <=> alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: trans-Golgi Network Coat Activation (Sus scrofa)


name: acetyl-CoA + ATP + hydrogencarbonate <=> ADP + H(+) + malonyl-CoA + phosphate


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate = plasmodiophorol B


name: FURIN translocates to the plasma membrane (Danio rerio)


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Canis familiaris)


name: GRK2 sequesters activated Gq (Xenopus tropicalis)


name: 7-aminomethyl-7-carbaguanine + 2 NADP(+) <=> 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH


name: an inositol-1-phosphoceramide + GDP-alpha-D-mannose => an alpha-mannosylinositol-1-phosphoceramide + GDP + H(+)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Canis familiaris)


name: HMGCR dimer reduces bHMG-CoA to MVA (Sus scrofa)


name: P2Y6 receptor can bind to UDP (Sus scrofa)


name: Lysosomal degradation of gap junction plaques (Canis familiaris)


name: PDE4A,C,D hydrolyse cAMP (Caenorhabditis elegans)


name: 2-oxo-3-sulfanylpropanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine


name: 1'-hydroxyversicolorone + H(+) + NADPH + O2 => (2S,3S)-versiconal hemiacetal acetate + H2O + NADP(+)


name: FN3KRP phosphorylates PsiAm, RibAm (Sus scrofa)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Homo sapiens)


name: IDUA hydrolyses Heparan sulfate chain(6) (Xenopus tropicalis)


name: 2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) <=> a cardiolipin + glycerol


name: ADP + H(+) + phosphate + thiamine(in) => ATP + H2O + thiamine(out)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Homo sapiens)


name: 2-oxopentanoate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminopentanoate


name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Homo sapiens)


name: RANBP2 SUMOylates PML with SUMO1 (Sus scrofa)


name: monoanhydrobacterioruberin <=> bisanhydrobacterioruberin + H2O


name: HMIT co-transports myo-inositol with a proton (Xenopus tropicalis)


name: 7-deoxyloganate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + loganate + oxidized [NADPH--hemoprotein reductase]


name: L-serine + NADP(+) <=> aminoacetaldehyde + CO2 + NADPH


name: CoA + H(+) + N-acetyl-D-glutamine => acetyl-CoA + D-glutamine


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Xenopus tropicalis)


name: arsenate reductase (glutaredoxin) activity


name: 10-deacetyl-2-debenzoylbaccatin III => 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: AH2 + gentamicin X2 + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + A + geneticin + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: 5,12-dihydroxanthommatin + NAD(+) <=> H(+) + NADH + xanthommatin


name: guanyl-nucleotide exchange factor activity


name: 7,8-dihydroxykynurenate + O2 => 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Canis familiaris)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + di-(9Z)-octadecenoylglycerol + H(+)


name: H2O + L-saccharopine + O2 => (S)-2-amino-6-oxohexanoate + H2O2 + L-glutamate


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Drosophila melanogaster)


name: 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol = 1alpha,2beta,25-trihydroxycholecalciferol + 3-hydroxypropanal


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + O2 => an (E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amine + H(+) + H2O2


name: IRE1 binds IRE1 forming dimer (Bos taurus)


name: ACSM2B-like proteins transform ST to ST-CoA (Rattus norvegicus)


name: ATP + dehydroepiandrosterone 3-sulfate(in) + H2O <=> ADP + dehydroepiandrosterone 3-sulfate(out) + H(+) + phosphate


name: H2O + UDP-alpha-D-glucose => alpha-D-galactose 1-phosphate + 2 H(+) + UMP


name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate + 5,7-dihydroxy-4-methylphthalide = 4-farnesyl-3,5-dihydroxy-6-methylphthalide + diphosphate


name: Rag dimer formation (Xenopus tropicalis)


name: Phosphorylation of the Emi1 DSGxxS degron by Plk1 (Xenopus tropicalis)


name: choline + H(+) + sn-glycerol 3-phosphate => H2O + sn-glycerol 3-phosphocholine


name: NEMO subunit of IKK complex binds to activated IRAK1 upon stimulation of TLR7/8 or 9. (Drosophila melanogaster)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Drosophila melanogaster)


name: Binding of TFIIIC to Type 2 promoter (Mus musculus)


name: Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Gallus gallus)


name: ATP + CoA + succinate => ADP + phosphate + succinyl-CoA


name: SCNN channels transport extracellular Na+ to cytosol (Mus musculus)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Plasmodium falciparum)


name: (3S)-hydroxydecanoyl-CoA + NAD(+) <=> 3-oxodecanoyl-CoA + H(+) + NADH


name: 2-oxoglutarate + 3(1)-hydroxy-L-isoleucine + O2 <=> (4S)-3(1),4-dihydroxy-L-isoleucine + CO2 + succinate


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Gallus gallus)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Sus scrofa)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Canis familiaris)


name: a fatty acyl-CoA + sphing-4-enine => an N-acylsphing-4-enine + CoA + H(+)


name: 2-glutathionyl-2-methylbut-3-en-1-ol + NAD(+) <=> 2-glutathionyl-2-methylbut-3-enal + H(+) + NADH


name: emodin + S-adenosyl-L-methionine => physcion + S-adenosyl-L-homocysteine


name: Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Drosophila melanogaster)


name: ADRA2A,B,C bind ADR,NAd (Caenorhabditis elegans)


name: H2O + L-glutamate + 2 oxidized [2Fe-2S]-[ferredoxin] = 2-oxoglutarate + 2 H(+) + NH4(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: H(+) + UDP-alpha-D-galacturonate = CO2 + UDP-beta-L-arabinopyranose


name: an aromatic primary alcohol + NAD(+) => an aromatic aldehyde + H(+) + NADH


name: VANGL2 is phosphorylated in response to WNT5A (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Caenorhabditis elegans)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = astellifadiene + diphosphate


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Bos taurus)


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Canis familiaris)


name: HSD17B11 dehydrogenates EST17b to E1 (Bos taurus)


name: NTRK2-phosphorylated FRS2 binds GRB2 (Mus musculus)


name: Adenylate cyclase produces cAMP (Rattus norvegicus)


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Canis familiaris)


name: SGSH hydrolyses Heparan sulfate chain(2) (Xenopus tropicalis)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Danio rerio)


name: 3 a quinol + protoporphyrin IX => 3 a quinone + protoporphyrinogen IX


name: Addition of nucleotides between position +11 and +30 (Rattus norvegicus)


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Rattus norvegicus)


name: H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate


name: "N-acetylmuramic acid 6-phosphate etherase"


name: dADP + H2O <=> 2'-deoxyadenosine + diphosphate


name: Bile salts bind FABP6 (Drosophila melanogaster)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serine <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-serine


name: 1-octanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA


name: H(+) + luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] 4'-O-beta-D-glucuronide + UDP => luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] + UDP-alpha-D-glucuronate


name: TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC (Mus musculus)


name: transforming growth factor beta receptor activity, type I


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Xenopus tropicalis)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-D-GlcNAc derivative + GDP-beta-L-fucose => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-beta-D-GlcNAc derivative + GDP + H(+)


name: dimethylallyl diphosphate + verruculogen = diphosphate + fumitremorgin A


name: [sulfur carrier]-SH + AH2 + N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine <=> 2-sulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + H(+) + L-methionine


name: 7,8-dihydroneopterin 3'-phosphate = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde phosphate


name: ent-kaur-16-en-19-ol + O2 + reduced [NADPH--hemoprotein reductase] => ent-kaur-16-en-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Schizosaccharomyces pombe)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: TP53 stimulates PIDD1 expression (Homo sapiens)


name: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] = (4S)-perillyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O => (2E)-2-hydroxypenta-2,4-dienoate + anthranilate + H(+)


name: N-acetyl-alpha-neuraminate => 2-deoxy-2,3-dehydro-N-acetylneuraminate + H2O


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Drosophila melanogaster)


name: (R)-carnitine + 3-methylbutanoyl-CoA <=> CoA + O-3-methylbutanoyl-(R)-carnitine


name: ARL1:GTP binds ARFIP2 (Drosophila melanogaster)


name: chloride(out) + 2 hydrogencarbonate(in) + Li(+)(in) = chloride(in) + 2 hydrogencarbonate(out) + Li(+)(out)


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Saccharomyces cerevisiae)


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Mus musculus)


name: 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Rattus norvegicus)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-leucine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-leucine


name: (2S)-2-methylbutanenitrile + O2 + reduced [NADPH--hemoprotein reductase] => 2-hydroxy-2-methylbutanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p-S363,S380,T573 RS6K translocates to the nucleus (Rattus norvegicus)


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Bos taurus)


name: 3-chloro-D-alanine => 2-aminoprop-2-enoate + chloride + H(+)


name: octadecanoyl-CoA + sphinganine => CoA + H(+) + N-(octadecanoyl)-sphinganine


name: D-maltose + H2O = alpha-D-glucose + D-glucose


name: IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Homo sapiens)


name: a 2-oxocarboxylate + H(+) + NADPH => a (2R)-2-hydroxycarboxylate + NADP(+)


name: L-proline(in) + Na(+)(in) <=> L-proline(out) + Na(+)(out)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + cholesterol


name: PGH2 is isomerised to PGE2 by PTGES (Bos taurus)


name: WIPIs bind PI3P (Saccharomyces cerevisiae)


name: MLCL is acylated to CL by HADH (IM) (Danio rerio)


name: RHOF binds effectors at the plasma membrane (Bos taurus)


name: 7,8-dihydroneopterin 3'-triphosphate + H2O => 7,8-dihydroneopterin 3'-phosphate + diphosphate + H(+)


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)


name: a ganglioside GD3 (d18:1(4E)) + CMP + H(+) => a ganglioside GM3 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: ATP + L-isoleucine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate = ADP + dapdiamide B + H(+) + phosphate


name: Activated FGFR3 phosphorylates FRS3 (Gallus gallus)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Rattus norvegicus)


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Danio rerio)


name: 17alpha-hydroxypregnenolone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + pregnenolone + reduced [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H(+) + malonyl-CoA = (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + CoA


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Caenorhabditis elegans)


name: GAP binds to PDGF-beta receptors only (Canis familiaris)


name: D-alanine + L-glutamine <=> gamma-L-glutamyl-D-alanine + NH4(+)


name: XPC binds RAD23 and CETN2 (Xenopus tropicalis)


name: L-lysine + NAD(+) <=> 2 H(+) + L-1-piperideine-6-carboxylate + NADH + NH4(+)


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Sus scrofa)


name: MET gene transcription is stimulated by MECP2 (Homo sapiens)


name: H2O + L-serine + O2 = 3-hydroxypyruvate + H2O2 + NH4(+)


name: ATPase-coupled L-glutamine transmembrane transporter activity


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Homo sapiens)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Drosophila melanogaster)


name: rifamycin SV hemiaminal <=> H(+) + rifamycin SV ortho-naphthoquinone carboxamide


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Danio rerio)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Saccharomyces cerevisiae)


name: CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Rattus norvegicus)


name: 1-octanoylglycerol + H2O = glycerol + H(+) + octanoate


name: 1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + octanoate


name: 1,2-didecanoyl-sn-glycero-3-phosphocholine + CMP + H(+) => 1,2-didecanoyl-sn-glycerol + CDP-choline


name: 2,3-dioxo-L-gulonate(out) + Na(+)(out) => 2,3-dioxo-L-gulonate(in) + Na(+)(in)


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Danio rerio)


name: a menaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + an 8-methylmenaquinone + 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L-homocysteine


name: FFAR1 binds rosiglitazone (Mus musculus)


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Danio rerio)


name: G13 activation by TP receptor (Sus scrofa)


name: cis-aconitate(in) + citrate(out) <=> cis-aconitate(out) + citrate(in)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate = 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Homo sapiens)


name: LC3:ATG7 dimer binds ATG3 (Drosophila melanogaster)


name: GPER:Heterotrimeric G-protein Gs binds ESTG (Xenopus tropicalis)


name: cholesterol + PAPS => cholesterol sulfate + PAP (Danio rerio)


name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Rattus norvegicus)


name: Melanocortin receptors bind melanocortins (Gallus gallus)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Mus musculus)


name: Release of noradrenaline  at the synapse (Caenorhabditis elegans)


name: Abortive Initiation Before Second Transition (Rattus norvegicus)


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Homo sapiens)


name: Phosphorylation and activation of VAV2/VAV3 by SYK (Mus musculus)


name: (24R)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (24R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)


name: Type B histone acetlytransferase complex acetylates histone H4 (Plasmodium falciparum)


name: didemethylasterriquinone D + dimethylallyl diphosphate => asterriquinone C1 + diphosphate


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Bos taurus)


name: intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Homo sapiens)


name: (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA => (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H2O


name: acetyl-CoA + dodecanedioyl-CoA => 3-oxotetradecanedioyl-CoA + CoA


name: H(+) + keto-D-tagaturonate + NADH => L-galactonate + NAD(+)


name: p-PKR dimer phosphorylates DHX9 (Xenopus tropicalis)


name: Exchange of oxygen with sulfur in MoCo (Sus scrofa)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in U6 snRNA + CO2 + formaldehyde + succinate => 2-oxoglutarate + a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in U6 snRNA + O2


name: Fe(III)-heme b-[protein] + nitrate => Fe(II)-heme b-[protein] + nitric oxide + O2


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Caenorhabditis elegans)


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Schizosaccharomyces pombe)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Mus musculus)


name: Dephosphorylation of CK2-modified condensin I (Drosophila melanogaster)


name: UGT1A10 transfers GlcA from UDP-GlcA to GCTN (Homo sapiens)


name: apo-Transferrin dissociates from the receptor complex (Bos taurus)


name: (E)-caffeate + H(+) + L-quinate => chlorogenate + H2O


name: VAV3 is a GEF for Rho/Rac family kinases (Mus musculus)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: acetate + H(+) + holo-[citrate lyase ACP] => acetyl-[citrate lyase ACP] + H2O


name: CAMK1 binds calmodulin (Canis familiaris)


name: CTLH E3 ligase ubiquitinates PKM-1 (Xenopus tropicalis)


name: Trimerization of the FASL:FAS receptor complex (Rattus norvegicus)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)


name: H2O + O2 + propionate 3-nitronate => 3-oxopropanoate + H(+) + H2O2 + nitrite


name: precorrin-4 + S-adenosyl-L-methionine => precorrin-5 + S-adenosyl-L-homocysteine


name: SUMOylation of EP300 with SUMO1 (Rattus norvegicus)


name: p-S-TBK1 phosphorylates OPTN (Bos taurus)


name: Association of Cx43 with TJP1 (Homo sapiens)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + 4-isopropylphenol <=> 4-isopropylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Canis familiaris)


name: 3-ethylmalate + CoA + H(+) => butanoyl-CoA + glyoxylate + H2O


name: CDC42 GDIs block activation of CDC42 (Dictyostelium discoideum)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose <=> a globoside Gb3Cer + H(+) + UDP


name: RAC2 GDIs block activation of RAC2 (Caenorhabditis elegans)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)


name: LCAT:discoidal HDL complex <=> LCAT + discoidal HDL (Sus scrofa)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose <=> 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: Disassembly of SR-BI-bound spherical HDL (Canis familiaris)


name: PLG(20-810) binds aprotinin (Canis familiaris)


name: MUL1 ubiquitinates UBXN7 (Drosophila melanogaster)


name: VRK1/VRK2 phosphorylate BANF1 (Homo sapiens)


name: 3-phenylpropanoate + H(+) + oxidized [electron-transfer flavoprotein] => (E)-cinnamate + reduced [electron-transfer flavoprotein]


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Mus musculus)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Homo sapiens)


name: Homodimerization of VEGF proteins (Homo sapiens)


name: (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H(+) + NADPH = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+)


name: The Interleukin 1 receptor complex binds Tollip (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ADP + H(+) + phosphate


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Canis familiaris)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Gallus gallus)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([3-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Sus scrofa)


name: TIRAP binds PIP2-rich regions in the plasma membrane (Gallus gallus)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)


name: Activated P2Y purinoceptor 12 binds G-protein Gi (Canis familiaris)


name: Nucleotide exchange on RAB1 (Plasmodium falciparum)


name: 3-dehydro-D-erythronate + ATP <=> 3-dehydro-4-O-phospho-D-erythronate + ADP + H(+)


name: RPE dimers isomerise RU5P to XY5P (Caenorhabditis elegans)


name: 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-octadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine


name: H(+) + N,N-dimethylaniline + NADPH + O2 => H2O + N,N-dimethylaniline N-oxide + NADP(+)


name: CDC42 and PIP2 bind WASL, activating it (Rattus norvegicus)


name: 2'-deoxyinosine + phosphate => 2-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine


name: chlorophyllide a + 2 H(+) = Mg(2+) + pheophorbide a


name: CR:atREs binds apoE and HSPG (Homo sapiens)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Drosophila melanogaster)


name: CYP4B1 12-hydroxylates ARA (Homo sapiens)


name: butyl acetate + CoA => acetyl-CoA + butan-1-ol


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Homo sapiens)


name: STON2 is neddylated (Dictyostelium discoideum)


name: 2 a plastoquinone + 2 H2O + 4 hnu <=> 2 a plastoquinol + O2


name: KIT binds type I TKIs (Xenopus tropicalis)


name: RHOD binds effectors at the Golgi membrane (Rattus norvegicus)


name: chloride(in) + Na(+)(in) => chloride(out) + Na(+)(out)


name: O2 + prostaglandin E1 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy prostaglandin E1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: WWP2 ubiquitinates NOTCH3 (Gallus gallus)


name: p-S407,Y641-STAT6 is dimerized (Canis familiaris)


name: Nuclear transport of pChREBP (Thr 666) protein (Drosophila melanogaster)


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Dictyostelium discoideum)


name: 11-O-acetylcyathin A3 + AH2 => 11-O-acetylcyathatriol + A


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Xenopus tropicalis)


name: phosphate + S-methyl-5'-thioadenosine <=> adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: 2-oxoglutarate + O2 + tetradecanoyl-CoA <=> 2-hydroxytetradecanoyl-CoA + CO2 + succinate


name: (9Z,12Z)-octadecadienoyl-CoA + 1-O-hexadecyl-2-acetyl-sn-glycerol => 1-O-hexadecyl-2-acetyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + CoA


name: (12R,13S)-epoxy-(10R)-hydroperoxy-(8E)-octadecenoate => (12R,13S)-epoxy-(9Z)-octadecenoate + O2


name: UROD decarboxylates URO3 to COPRO3 (Canis familiaris)


name: ING2 recruits EP300 to TP53 (Rattus norvegicus)


name: KSPG is secreted from the cell (Canis familiaris)


name: a 5'-end diphospho-ribonucleoside in mRNA + H(+) + phosphate => a 5'-end triphospho-ribonucleoside in mRNA + H2O


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Sus scrofa)


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Mus musculus)


name: 2-oxoglutarate + L-cysteine => 2-oxo-3-sulfanylpropanoate + L-glutamate


name: SUMOylation of DAXX with SUMO1 (Mus musculus)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Xenopus tropicalis)


name: (2E)-geranyl diphosphate => (-)-beta-phellandrene + diphosphate


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Saccharomyces cerevisiae)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + H(+) + hexadecanoate => 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O


name: hexadecanoyl-CoA + sphinga-(4E,8E)-dienine = CoA + H(+) + N-hexadecanoylsphinga-(4E,8E)-dienine


name: ASICs bind STOML3, (STOM) (Canis familiaris)


name: PGLYRP3,4 binds bacterial peptidoglycan (Sus scrofa)


name: Defective AVP mutants do not bind AVPR1A,B (Homo sapiens)


name: YWHAB dimer dissociates from KSR1:MARK3 (Drosophila melanogaster)


name: RANBP2 SUMOylates PML with SUMO2 (Homo sapiens)


name: H2O + N-hexacosanoylglycine => glycine + hexacosanoate


name: cyclohexanone + H(+) + NADPH + O2 => H2O + hexano-6-lactone + NADP(+)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)


name: RHOD translocates to the mitochondrial outer membrane (Caenorhabditis elegans)


name: UDP-alpha-D-galactose + UDP-N-acetyl-alpha-D-glucosamine => H(+) + UDP-N-acetyl-6-(alpha-D-galactose-1-phospho)-alpha-D-glucosamine + UMP


name: H(+) + ilicicolin C + NADPH + O2 => ascochlorin + 2 H2O + NADP(+)


name: OPTN recruits CYLD to the TNFR1 complex (Canis familiaris)


name: Metabotropic glutamate receptors bind glutamate (Mus musculus)


name: SLC52A1,2,3 transport RIB from extracellular region to cytosol (Danio rerio)


name: Endosomal TLRs pass through the Golgi (Danio rerio)


name: 2-oxoglutarate(out) + citrate(in) = 2-oxoglutarate(in) + citrate(out)


name: TP receptor can bind thromboxane (Gallus gallus)


name: 2-MAG is transacylated to DAG by PNPLA2/3 (Plasmodium falciparum)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Canis familiaris)


name: ALDH2 transforms GTN to NO (Caenorhabditis elegans)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Rattus norvegicus)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Gallus gallus)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Bos taurus)


name: (3R)-hydroxytetracosanoyl-CoA + NAD(+) <=> 3-oxotetracosanoyl-CoA + H(+) + NADH


name: acetoin + CoA + NAD(+) => acetaldehyde + acetyl-CoA + H(+) + NADH


name: G-protein gated potassium channel activity


name: LYPLA2 hydrolyses PALM-C3,4-GAP43 (Rattus norvegicus)


name: Phosphorylation of PLCgamma by PDGFR (Danio rerio)


name: beta-amyrin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 11-oxo-beta-amyrin + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) => 4,5-dihydroxyphthalate + H(+) + NADH


name: NOTCH4 gene transcription is inhibited by RUNX1 (Homo sapiens)


name: a ganglioside GT1b (d18:1(4E)) + H2O => a ganglioside GD1b (d18:1(4E)) + N-acetylneuraminate


name: STAB2:ligand is endocytosed (Canis familiaris)


name: MRE11 binds cytosolic DNA (Homo sapiens)


name: SUMOylation of PCNA with SUMO1 (Danio rerio)


name: HRH3 binds pitosilant (Rattus norvegicus)


name: H(+)(out) + N-acetyl-L-aspartyl-L-glutamate(out) => H(+)(in) + N-acetyl-L-aspartyl-L-glutamate(in)


name: NCOA2(869-1464) binds KAT6A(1-1118) (Rattus norvegicus)


name: an alcohol + D-glucuronate => an alpha-D-glucuronoside + H2O


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Mus musculus)


name: a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + AMP + H(+) => a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + GTP


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Canis familiaris)


name: CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Schizosaccharomyces pombe)


name: an N-acylsphing-4-enine + H2O => a fatty acid + sphing-4-enine


name: Duplex siRNA is loaded into Argonaute (Mus musculus)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 4-amino-5-hydroxy-3-all-trans-hexaprenylbenzoate + 5 H(+) + O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + NH4(+) + 4 oxidized [2Fe-2S]-[ferredoxin]


name: a ganglioside GM1b + UDP-N-acetyl-alpha-D-galactosamine = ganglioside GalNAc-GM1b + H(+) + UDP


name: Loss of SAR1B GTPase (Rattus norvegicus)


name: (2E)-butenoyl-CoA + L-lysyl-[protein] => CoA + H(+) + N(6)-(2E)-butenoyl-L-lysyl-[protein]


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Caenorhabditis elegans)


name: Formation of TSC1:TSC2 complex (Mus musculus)


name: RUNX1 binds PRMT1 (Drosophila melanogaster)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Schizosaccharomyces pombe)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Rattus norvegicus)


name: menaquinone-7 + succinate <=> fumarate + menaquinol-7


name: p-T182 MAPKAPK5 phosphorylates FOXO3 (Mus musculus)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Homo sapiens)


name: oxaloacetate(in) + sulfate(out) <=> oxaloacetate(out) + sulfate(in)


name: PTPN11 dephosphorylates RUNX1 (Mus musculus)


name: ammelide + NH4(+) => ammeline + H(+) + H2O


name: (2E,6E)-farnesyl diphosphate => african-1-ene + diphosphate


name: Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Rattus norvegicus)


name: NADPH + O2 + rifampicin = H(+) + H2O + NADP(+) + rifampicin para-naphthoquinone carboxamide


name: Regorafenib-resistant KIT mutants do not bind regorafenib (Homo sapiens)


name: ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Bos taurus)


name: 1,2-epoxypropane + H2O <=> propane-1,2-diol


name: (3S)-hydroxydocosanoyl-CoA => (2E)-docosenoyl-CoA + H2O


name: 5,10-methylenetetrahydromethanopterin + 2 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) => 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Caenorhabditis elegans)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Schizosaccharomyces pombe)


name: Active LTK recruits GRB2:SOS1 (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: ME3 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)


name: 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin] => 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: Conjugation of SUMO1 to UBA2:SAE1 (Dictyostelium discoideum)


name: Frataxin transfers Fe2+ to ACO2 (Schizosaccharomyces pombe)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Bos taurus)


name: TAT deaminates tyrosine (Drosophila melanogaster)


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Mus musculus)


name: 8-hydroxycopalyl diphosphate + H2O => diphosphate + sclareol


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: NPPA(124-151) binds NPR1 (Xenopus tropicalis)


name: pro-F2R binds vorapaxar (Canis familiaris)


name: HYAL1 hydrolyses (HA)50 (Rattus norvegicus)


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Rattus norvegicus)


name: GDIs block activation of RHOB (Rattus norvegicus)


name: (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) => 2,3-dihydroxy-p-cumate + H(+) + NADH


name: a ribonucleoside 5'-diphosphate + dCMP + H(+) => 2'-deoxycytidine + a ribonucleoside 5'-triphosphate


name: a 1-acylglycerol + H2O => a fatty acid + glycerol + H(+)


name: SLC4A4 cotransports Na+ with 3HCO3- (Homo sapiens)


name: AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA <=> 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]


name: Nuclear transport of pChREBP (Thr 666) protein (Canis familiaris)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Mus musculus)


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Homo sapiens)


name: ATP + methylphosphonate <=> adenine + alpha-D-ribose 1-methylphosphonate 5-triphosphate


name: Formation of MCM2-7 complex (Xenopus tropicalis)


name: [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) => [TtuB sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: H2O + S-adenosyl-L-homocysteine => adenine + S-(5-deoxy-D-ribos-5-yl)-L-homocysteine


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Xenopus tropicalis)


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Xenopus tropicalis)


name: 1-acyl-2-(9Z)-enoyl-sn-glycero-3-phospholipid + S-adenosyl-L-methionine <=> 1-acyl-2-(10-methylene)-acyl-sn-glycero-3-phospholipid + H(+) + S-adenosyl-L-homocysteine


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Sus scrofa)


name: bornane-2,6-dione + H2O <=> [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate + H(+)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Canis familiaris)


name: 4-terpineol + diphosphate => (2E)-geranyl diphosphate + H2O


name: Dephosphorylation of Lck-pY505 by CD45 (Homo sapiens)


name: PHF8 demethylates histone H4K20me1 (Schizosaccharomyces pombe)


name: 3-oxopropanoate + H(+) <=> acetaldehyde + CO2


name: Ubiquitinated Orc1 enters the cytosol (Canis familiaris)


name: H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP => 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: Basigin homodimerises (Rattus norvegicus)


name: H2O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate


name: H2O + O2 + sarcosine => formaldehyde + glycine + H2O2


name: Phosphorylation of L1 by ERK (Gallus gallus)


name: AURKA phosphorylates TP53 (Mus musculus)


name: chloride + FADH2 + melleolide F + O2 => 6'-chloromelleolide F + FAD + H(+) + 2 H2O


name: ATP + D-erythrulose => ADP + D-erythrulose 4-phosphate + H(+)


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Caenorhabditis elegans)


name: H(+) + pyrrole-2-carboxylate => 1H-pyrrole + CO2


name: glutathione disulfide + L-ascorbate => 2 glutathione + L-dehydroascorbate


name: a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide + H(+) + S-adenosyl-L-homocysteine => a (4E,8E)-4-sphinga-4,8-dienine ceramide + S-adenosyl-L-methionine


name: GOPC promotes translocation of CFTR to lysosomes (Danio rerio)


name: lactose + H2O => D-glucose + D-galactose (Rattus norvegicus)


name: L-alanine + pyridoxal 5'-phosphate => pyridoxamine 5'-phosphate + pyruvate


name: 6-deoxo-28-norcastasterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 6alpha-hydroxy-28-norcastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CoA + H(+) + N(6)-butanoyl-L-lysyl-[protein] => butanoyl-CoA + L-lysyl-[protein]


name: H(+) + prephenate = 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+) => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: 3-dehydro-D-glucose + D-fructose => 3-dehydro-alpha-D-glucosyl beta-D-fructofuranoside + H2O


name: Cleavage of intergenic spacer RNA to yield fragments of 150-300 nucleotides (Homo sapiens)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Mus musculus)


name: (1R,4S)-isodihydrocarvone + A => (S)-carvone + AH2


name: (2E)-octenoyl-CoA + H2O = (3R)-hydroxyoctanoyl-CoA


name: (2E)-geranyl diphosphate => (-)-car-3-ene + diphosphate


name: FGFR2b binds to FGF (Caenorhabditis elegans)


name: 2 L-ascorbate + O2 = 2 H2O + 2 L-dehydroascorbate


name: RNF8 and RNF168 ubiquitinate H2AFX (Rattus norvegicus)


name: SUMOylation of DNMT3B with SUMO1 (Sus scrofa)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Schizosaccharomyces pombe)


name: a 2-deoxystreptamine antibiotic + acetyl-CoA => an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)


name: calcium-dependent protein kinase inhibitor activity


name: 2-acyl LPG is acylated to PG by LPGAT (Saccharomyces cerevisiae)


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Homo sapiens)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Homo sapiens)


name: NOSTRIN mediated translocation of eNOS from plasma membrane (Rattus norvegicus)


name: ATP + H2O + taurolithocholate 3-sulfate(in) = ADP + H(+) + phosphate + taurolithocholate 3-sulfate(out)


name: Translocation of YAP1 to the nucleus (Mus musculus)


name: ST8SIA5 transfers Neu5Ac to gangliosides (Homo sapiens)


name: IL12B translocates from the cytosol to the extracellular region (Homo sapiens)


name: ATP + glycine betaine(out) + H2O = ADP + glycine betaine(in) + H(+) + phosphate


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Gallus gallus)


name: a (2E)-enoyl-[ACP] + H(+) + NADH => a 2,3-saturated acyl-[ACP] + NAD(+)


name: GSK3B phosphorylates p-NFE2L2 (Caenorhabditis elegans)


name: A + a 3-oxo-Delta(4)-steroid <=> a 3-oxo-Delta(1,4)-steroid + AH2


name: OGDH dimer decarboxylates 2-OG (Dictyostelium discoideum)


name: HSD17B3-like proteins reducde ANDST to TEST (Dictyostelium discoideum)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: Cho is phosphorylated to PCho by CHK dimer (Danio rerio)


name: Phosphorylation of LIMK-1 by PAK (Drosophila melanogaster)


name: C30 botryococcene + 2 S-adenosyl-L-methionine => 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: PTGS1 dimer binds PTGS1 Inhibitors (Xenopus tropicalis)


name: IDUA hydrolyses Heparan sulfate chain(1) (Bos taurus)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole = 12-epi-fischerindole U


name: L-glutamate + leukotriene D4 => H2O + leukotriene C4


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Gallus gallus)


name: 4-hydroxy-2-oxoheptanedioate <=> pyruvate + succinate semialdehyde


name: GOLGA2 phosphorylated by CDK1 is unable to promote fusion of ER to Golgi transport vesicles with cis-Golgi (Homo sapiens)


name: Ubiquitinated DVL1 is degraded by the proteasome (Canis familiaris)


name: 2',3'-cyclophospho-CMP + H2O <=> 3'-CMP + H(+)


name: Formation of Ragulator complex (Bos taurus)


name: ULK1 phosphorylates RIPK1 at S357 (Mus musculus)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Danio rerio)


name: cephalosporin C + H2O <=> acetate + deacetylcephalosporin C + H(+)


name: H(+) + H2O + juvenile hormone III carboxylate + oxidized [NADPH--hemoprotein reductase] => (2E,6E)-farnesoate + O2 + reduced [NADPH--hemoprotein reductase]


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Mus musculus)


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Danio rerio)


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Sus scrofa)


name: cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine => H(+) + N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine


name: anthocyanin A11 + D-glucose => 1-O-(trans-sinapoyl)-beta-D-glucose + anthocyanin A8


name: USP49 deubiquitinates H2B (Canis familiaris)


name: USP18 deubiquitinates TAK1:TAB1 (Bos taurus)


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Bos taurus)


name: KDSR reduces 3-ketosphingoid (Schizosaccharomyces pombe)


name: Conversion of PA into DAG by PAP-1 (Canis familiaris)


name: but-3-ynal + H2O + NAD(+) => 3-butynoate + 2 H(+) + NADH


name: a 1,2-diacylglycerol + a fatty acid + H(+) => a triacylglycerol + H2O


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Gallus gallus)


name: 2,4'-dihydroxyacetophenone + O2 = 4-hydroxybenzoate + formate + 2 H(+)


name: 26S proteosome degrades ODC holoenzyme complex (Mus musculus)


name: Activated CEBPB stimulates transcription of CDKN2B (Homo sapiens)


name: CLCN7:OSTM1 exchanges Cl- for H+ (Bos taurus)


name: a ganglioside GM2 (d18:1(4E)) + H2O => a ganglioside GA2 (d18:1(4E)) + N-acetylneuraminate


name: ORC2 binds ORC3 (Schizosaccharomyces pombe)


name: 2-hydroxy-5-carboxymethylmuconate semialdehyde + H(+) => 3,4-dihydroxyphenylacetate + O2


name: Phosphorylated STAT1, STAT3 form dimers (Danio rerio)


name: D-galactose 6-phosphate + NADP(+) <=> 6-phospho-D-galactono-1,5-lactone + H(+) + NADPH


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Rattus norvegicus)


name: Binding of A1CF to stem-looped RNA (Sus scrofa)


name: PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Dictyostelium discoideum)


name: dimethylallyl diphosphate + siccayne <=> diphosphate + pestalodiol


name: Caspase-mediated cleavage of Z0-2 (Drosophila melanogaster)


name: epoxypheophorbide a + H2O <=> H(+) + red chlorophyll catabolite


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Mus musculus)


name: 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + an N-acetyl-L-cysteine-S-conjugate => H2O + mycothiol S-conjugate


name: H(+) + NADPH + UDP-4-dehydro-beta-L-rhamnose = NADP(+) + UDP-beta-L-rhamnose


name: 4-methylphenol + CO2 => 4-hydroxyphenylacetate + H(+)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Xenopus tropicalis)


name: Exocytosis of specific granule lumen proteins (Drosophila melanogaster)


name: Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Gallus gallus)


name: PREX2 binds PTEN and inhibits it (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+) => 1-O-(1Z)-hexadecenyl-2 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O


name: an adenosine in tRNA + S-adenosyl-L-methionine <=> an N(6)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 23S,25-dihydroxy-24-oxocholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: FOXG1 binds FOXO:SMAD complexes (Mus musculus)


name: The receptor:G-protein complex releases GDP (Sus scrofa)


name: alfacalcidol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> calcitriol + H2O + 2 oxidized [adrenodoxin]


name: Phosphorylation of Cx43 by c-src (Sus scrofa)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Mus musculus)


name: Y693-STAT4 dimer translocates to the nucleus (Sus scrofa)


name: AKR dimers reduce AFBDHO to AFBDOH (Mus musculus)


name: 15-demethylaclacinomycin T + AH2 + O2 <=> 10-decarboxymethylaclacinomycin T + A + CO2 + H2O


name: H2O + leukotriene C4 <=> L-glutamate + leukotriene D4


name: TGFBR2 is recruited to tight junctions after TGF-beta stimulation (Homo sapiens)


name: ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oryzalexin E + oxidized [NADPH--hemoprotein reductase]


name: Deubiquitinated PTEN translocates to the cytosol (Gallus gallus)


name: NSF and SNAPs bind the cis-SNARE at the Golgi (Saccharomyces cerevisiae)


name: TXNIP binds reduced thioredoxin (Homo sapiens)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Sus scrofa)


name: ZFP36 (TTP) recruits RNA degradation activities (Bos taurus)


name: NME1,2 hexamers phosphorylate RBV-DP (Xenopus tropicalis)


name: [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 2 H(+) + 3 H2O + nicotinamide => [ADP-thiazole synthase]-L-cysteine + glycine + NAD(+)


name: ATP + glutathione(in) + H2O + taurocholate(in) <=> ADP + glutathione(out) + H(+) + phosphate + taurocholate(out)


name: tRNA (uridine) methyltransferase activity


name: L-homocysteine + succinate => hydrogen sulfide + O-succinyl-L-homoserine


name: Asc.- radical dissociates to AscH- and DeHA (Homo sapiens)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Rattus norvegicus)


name: a 3alpha-hydroxy bile acid CoA + NAD(+) = a 3-oxo bile acid CoA + H(+) + NADH


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Canis familiaris)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Saccharomyces cerevisiae)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: N-WASP binds ARP2/3 and G-actin (Canis familiaris)


name: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4(+)


name: TDO tetramer dioxygenates L-Trp to NFK (Drosophila melanogaster)


name: (5S)-hydroxy-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase] <=> 5-oxo-(6E,8Z)-octadecadienoate + H(+) + 2 H2O + oxidized [NADH--hemoprotein reductase]


name: Removal of repair proteins and ligation of the processed ends of the DNA double-strand break (Gallus gallus)


name: ATP + ecdysone = ADP + ecdysone 22-phosphate + H(+)


name: Caspase-mediated cleavage of alpha adducin (Gallus gallus)


name: ADP + H(+) + sphing-4-enine 1-phosphate => ATP + sphing-4-enine


name: alpha-thujene + diphosphate => (2E)-geranyl diphosphate


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Homo sapiens)


name: 1D-myo-inositol 3-phosphate + CDP-2,3-bis-O-(phytanyl)-sn-glycerol <=> CMP + H(+) + saturated 1-archaetidyl-1D-myo-inositol 3-phosphate


name: ganglioside GM2 (d18:1(4E)/18:0) + H2O <=> ganglioside GA2 (d18:1(4E)/18:0) + N-acetylneuraminate


name: SCD5 desaturates ST-CoA to OLE-CoA (Schizosaccharomyces pombe)


name: CTP(out) + GDP(in) <=> CTP(in) + GDP(out)


name: 2xENPP1 hydrolyzes FAD to FMN (Schizosaccharomyces pombe)


name: an aromatic aldehyde + H2O + NAD(+) <=> an aromatic carboxylate + 2 H(+) + NADH


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Drosophila melanogaster)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Plasmodium falciparum)


name: MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)


name: β-blockers bind ADRB1,2,3 (Mus musculus)


name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Schizosaccharomyces pombe)


name: (9Z,11E)-octadecadienoate + H2O => 10-hydroxy-(11E)-octadecenoate


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine = 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: acetyl-CoA + N-terminal L-aspartyl-L-aspartyl-L-aspartyl-[protein] => CoA + H(+) + N-terminal N-acetyl-L-aspartyl-L-aspartyl-L-aspartyl-[protein]


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Bos taurus)


name: SIRT3 deacetylates AcK-IDH2 dimer (Canis familiaris)


name: H(+) + H2O + oryzalexin D + oxidized [NADPH--hemoprotein reductase] => ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: RPS6KA1-dependent phosphorylation of MITF-M (Xenopus tropicalis)


name: 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + O2 => a 2'-deoxycytidine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate => ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate


name: (S)-malate(out) + citrate(in) => (S)-malate(in) + citrate(out)


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Drosophila melanogaster)


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Bos taurus)


name: Association of procollagen type XXVI (Canis familiaris)


name: D-glucose 6-sulfate + NADP(+) = 6-sulfo-D-glucono-1,5-lactone + H(+) + NADPH


name: AcK-NFE2L2-dependent GCLC gene expression (Homo sapiens)


name: dTDP-beta-L-daunosamine + epsilon-rhodomycinone <=> dTDP + H(+) + rhodomycin D


name: hexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 16-hydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+)(in) + indole(in) => H(+)(out) + indole(out)


name: KDSR reduces 3-ketosphingoid (Bos taurus)


name: molybdate ion transmembrane transporter activity


name: NSF and SNAPs bind cis-SNARE complex (Saccharomyces cerevisiae)


name: [DsrC protein]-disulfide + H(+) + hydrogen sulfide = [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine


name: 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol <=> 25-hydroxy-24-oxocalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Mus musculus)


name: 3'-phosphoadenylyl sulfate + H2O => adenosine 5'-phosphosulfate + phosphate


name: (20S)-hydroxypregn-4-en-3-one + NAD(+) <=> H(+) + NADH + progesterone


name: AKT-phosphorylated FOXO3 translocates to cytosol (Homo sapiens)


name: HMOX1 translocates from the cytosol to the nucleoplasm (Canis familiaris)


name: TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Mus musculus)


name: 1-hexadecanoylglycerone 3-phosphate + tetradecan-1-ol = 1-O-tetradecylglycerone 3-phosphate + H(+) + hexadecanoate


name: (11Z)-octadecenoyl-CoA + NADP(+) => (2E,11Z)-octadecadienoyl-CoA + H(+) + NADPH


name: Interleukin-1 receptor type 1: Interleukin 1 binds Interleukin-1 receptor accessory protein, membrane associated isoform (Gallus gallus)


name: dihydroxyacetone phosphate + formaldehyde => L-erythrulose 1-phosphate


name: Phosphorylation of pPTK2 by SRC (Sus scrofa)


name: SRD5A1 dehydrogenates TEST to DHTEST (Xenopus tropicalis)


name: a ganglioside Ac-O-7-GD3(d18:1(4E)) + CoA => a ganglioside GD3 (d18:1(4E)) + acetyl-CoA


name: 3-hydroxy-D-kynurenine + S-adenosyl-L-methionine = 3-hydroxy-4-methyl-D-kynurenine + H(+) + S-adenosyl-L-homocysteine


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 26-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O => (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H(+)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3] + succinate


name: Fe(III)-{di[N-(2,3-dihydroxybenzoyl)-L-seryl]-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + H(+) + H2O <=> Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + N-(2,3-dihydroxybenzoyl)-L-serine


name: Inactivation of MAP2K1 by CDK1 (Bos taurus)


name: ADP + H(+) + phosphate + taurocholate(out) => ATP + H2O + taurocholate(in)


name: RAC1 GDIs block activation of RAC1 (Danio rerio)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Drosophila melanogaster)


name: ub-GLI is degraded by the proteasome (Rattus norvegicus)


name: (+)-premalbrancheamide + bromide + FAD + 2 H(+) = (+)-malbrancheamide C + FADH2


name: 5beta-cholestane-3alpha,7alpha-diol + O2 + reduced [NADPH--hemoprotein reductase] <=> 5beta-cholestane-3alpha,7alpha,25-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a (3R)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O


name: 17alpha-estradiol + NADP(+) = estrone + H(+) + NADPH


name: CHPF,CHPF2,CHSY3 transfer GlcA to chondroitin (Bos taurus)


name: Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane (Homo sapiens)


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain (Canis familiaris)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Mus musculus)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Drosophila melanogaster)


name: Cleavage of hypoxanthine by MPG glycosylase (Xenopus tropicalis)


name: HMGB1 release from cells (Dictyostelium discoideum)


name: dimethylamine + formaldehyde + reduced [electron-transfer flavoprotein] => H(+) + H2O + oxidized [electron-transfer flavoprotein] + trimethylamine


name: ATP + L-arginine + L-tyrosine = AMP + diphosphate + H(+) + L-tyrosyl-L-arginine


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Sus scrofa)


name: DCC interacts with DIP13alpha (Bos taurus)


name: Trans-autophosphorylation of ERBB4 homodimers (Danio rerio)


name: Active PLC-gamma1 dissociates from EGFR (Gallus gallus)


name: H(+) + H2O + N,N-dihydroxy-L-tryptophan + oxidized [NADPH--hemoprotein reductase] => N-hydroxy-L-tryptophan + O2 + reduced [NADPH--hemoprotein reductase]


name: 3'-phosphoadenylyl sulfate + taurolithocholate => adenosine 3',5'-bisphosphate + H(+) + taurolithocholate 3-sulfate


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Homo sapiens)


name: 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: IKKbeta phosphorylates IkB causing NF-kB to dissociate (Mus musculus)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Canis familiaris)


name: KDSR reduces 3-ketosphingoid (Homo sapiens)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Rattus norvegicus)


name: Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP (Sus scrofa)


name: cortisol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 18-hydroxycortisol + H2O + 2 oxidized [adrenodoxin]


name: PKA phosphorylates DARPP-32 on Thr34 (Bos taurus)