name: AFG3L2 degrades mitochondrial matrix proteins (Bos taurus)


name: D-xylonate <=> 2-dehydro-3-deoxy-D-arabinonate + H2O


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Canis familiaris)


name: "non-chaperonin molecular chaperone ATPase"


name: butanoyl-CoA + hexan-1-ol <=> CoA + hexyl butanoate


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 <=> (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate


name: Phosphorylation of H2AX at S139 by ATM at the site of DSB (Gallus gallus)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+) => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose


name: 2 glutathione + NAD(+) => glutathione disulfide + H(+) + NADH


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Homo sapiens)


name: MAPK1-dependent phosphorylation of MITF-M (Gallus gallus)


name: PIAS2,3,4 SUMOylate RORA with SUMO2 (Mus musculus)


name: Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)


name: a long-chain fatty acid + ethanolamine => H2O + N-(long-chain fatty acyl)ethanolamine


name: an acyl-CoA + sn-glycero-3-phosphoethanolamine = a monoacyl-sn-glycero-3-phosphoethanolamine + CoA


name: carbamoyl adenylate + kanamycin A <=> 6''-O-carbamoylkanamycin A + AMP + H(+)


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Homo sapiens)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Caenorhabditis elegans)


name: ATP + H2O + N-all-trans-retinylidenephosphatidylethanolamine(out) <=> ADP + H(+) + N-all-trans-retinylidenephosphatidylethanolamine(in) + phosphate


name: a ganglioside GT1aalpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: RUNX1 binds FOXP3 (Caenorhabditis elegans)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Xenopus tropicalis)


name: SENP1,2,5 proteolytically process SUMO3 (Gallus gallus)


name: Activation of CHEK1 at resected DNA DSBs (Canis familiaris)


name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin (Mus musculus)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->6)-N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + H(+) + UDP => 3-O-[N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Dictyostelium discoideum)


name: PMM1,2 isomerise Man6P to Man1P (Xenopus tropicalis)


name: ATP + H(+) + NADPH + propanoate => AMP + diphosphate + NADP(+) + propanal


name: CDK5 phosphorylates DARPP-32 on Thr75 (Homo sapiens)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Gallus gallus)


name: ORC1 translocates to the nucleus (Homo sapiens)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Xenopus tropicalis)


name: (2R,3S)-3-methylmalate => 2-methylmaleate + H2O


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Bos taurus)


name: CoA + H2O => (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: Joining of adjacent Okazaki fragments (Schizosaccharomyces pombe)


name: (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: (1R,5R)-beta-pinene + diphosphate => (2E)-geranyl diphosphate


name: Translocation of Ezrin to plasma membrane (Canis familiaris)


name: Translocation of COP1 from the nucleus to the cytoplasm (Sus scrofa)


name: tBID binds to inactive BAX protein (Homo sapiens)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Gallus gallus)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] <=> daturadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RAC1 and CDC42 activate PAK2 (Mus musculus)


name: a 1-acyl-sn-glycero-3-phosphate + dodecanoyl-CoA = a 1-acyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: 2 AH2 + all-trans-4,4'-diaponeurosporene + 2 O2 = 4,4'-diaponeurosporenal + 2 A + 3 H2O


name: eburicol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 14-demethyleburicol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Homo sapiens)


name: diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine


name: "Acting on carbohydrates and derivatives"


name: 5-methyl-3-oxohexanoyl-[ACP] + CO2 + CoA => 3-methylbutanoyl-CoA + H(+) + malonyl-[ACP]


name: PRKACA phosphorylates TFAM in the mitochondrial matrix (Canis familiaris)


name: GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Rattus norvegicus)


name: Activated FGFR2 phosphorylates SHC1 (Mus musculus)


name: G-protein alpha subunit is inactivated (Sus scrofa)


name: UROD decarboxylates URO1 to COPRO1 (Bos taurus)


name: (22R)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Bos taurus)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Gallus gallus)


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Saccharomyces cerevisiae)


name: 11beta,17beta-dihydroxyandrost-4-ene-3-one + NAD(+) <=> 17beta-hydroxyandrost-4-ene-3,11-dione + H(+) + NADH


name: benzylmalonyl-CoA + H(+) + O2 = (E)-cinnamoyl-CoA + CO2 + H2O2


name: (+)-malbrancheamide + FADH2 => (+)-isomalbrancheamide B + chloride + FAD + 2 H(+)


name: keto-D-fructose 6-phosphate => keto-D-tagatose 6-phosphate


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Homo sapiens)


name: L-ornithine(out) + putrescine(in) = L-ornithine(in) + putrescine(out)


name: CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Caenorhabditis elegans)


name: [(3R)-hydroxybutanoate](n) + H2O => (3R)-hydroxybutanoate trimer + [(3R)-hydroxybutanoate](n-3) + H(+)


name: 2 H(+) + hexadecanoyl-CoA + 2 NADPH = CoA + hexadecan-1-ol + 2 NADP(+)


name: PP5 dephosphorylates RAF1 S338 (Bos taurus)


name: butanoyl-CoA + phosphate = butanoyl phosphate + CoA


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Xenopus tropicalis)


name: (S)-2,3-dihydrodipicolinate + NADP(+) <=> dipicolinate + H(+) + NADPH


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Canis familiaris)


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)


name: a carboxylate(in) + orotate(out) => a carboxylate(out) + orotate(in)


name: H2O + tetradecanoyl-CoA <=> CoA + H(+) + tetradecanoate


name: (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Danio rerio)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Canis familiaris)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O2 => (6S)-5,6,7,8-tetrahydrofolate + O2 + sarcosine


name: ADP(out) + dAMP(in) + H(+)(out) <=> ADP(in) + dAMP(out) + H(+)(in)


name: SHP1 and SHP2 bind the common beta chain (Bos taurus)


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Drosophila melanogaster)


name: NAD(+) + scyllo-inositol => H(+) + NADH + scyllo-inosose


name: 2xPPCS ligates PPanK with Cys (Danio rerio)


name: 2 H2O + isopenicillin N => N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2


name: Activated PKC phosphorylates SHC1 (Mus musculus)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Dictyostelium discoideum)


name: WIPI2 binds ATG12:ATG5:ATG16L (Gallus gallus)


name: Phosphorylation of cohesin by PLK1 at chromosomal arms (Bos taurus)


name: Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Bos taurus)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O => 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Saccharomyces cerevisiae)


name: Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) (Homo sapiens)


name: 2 H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) => 2 H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out)


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Drosophila melanogaster)


name: glutathione + prostaglandin A2 => prostaglandin A2-S-(R)-glutathione


name: Budding of connexon-containing transport vesicles from the Golgi (Bos taurus)


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Drosophila melanogaster)


name: DCAKD phosphorylates DP-CoA (Xenopus tropicalis)


name: 2-dehydro-3-deoxy-L-galactonate => L-glyceraldehyde + pyruvate


name: COQ2 ligates all-E-10PrP2 to PHB (Mus musculus)


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Drosophila melanogaster)


name: EPH:EFN tetramers oligomerise (Rattus norvegicus)


name: DENND6A,B exchange GTP for GDP on RAB14 (Drosophila melanogaster)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Saccharomyces cerevisiae)


name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Canis familiaris)


name: SREBP1A,1C,2 translocates to the nucleus (Sus scrofa)


name: 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + H2O + phosphoenolpyruvate = N,N-diacetyllegionaminate + phosphate


name: 3 [thioredoxin]-dithiol + arsenic triglutathione + 3 S-adenosyl-L-methionine <=> 3 [thioredoxin]-disulfide + 3 glutathione + 3 H(+) + 3 S-adenosyl-L-homocysteine + trimethylarsine


name: RRAGA,B exchanges GDP for GTP (Homo sapiens)


name: acetophenone + H(+) + NADH => (S)-1-phenylethanol + NAD(+)


name: MAPK4,6 translocate to the cytoplasm (Homo sapiens)


name: Active LTK receptor phosphorylates SHC1 (Gallus gallus)


name: 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+) => 5-(2-hydroxyethyl)-4-methylthiazole + ATP


name: Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA (Drosophila melanogaster)


name: Activated integrin alphaIIb beta3 binds SHC1 (Drosophila melanogaster)


name: hexadecanoyl-[ACP] + phosphate = hexadecanoyl phosphate + holo-[ACP]


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP


name: L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-homocysteine


name: "ribosomal protein uL3 N(5)-glutamine methyltransferase"


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-2,3-dihydrogenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Canis familiaris)


name: RAC1 binds effectors at the ER membrane (Canis familiaris)


name: H(+) + NADPH + phyllostine => isoepoxydon + NADP(+)


name: 2-methylpropan-1-amine + FADH2 + O2 => FAD + 2 H(+) + H2O + N-(2-methylpropyl)hydroxylamine


name: CYP11B2 oxidises 11DCORST to CORST (Homo sapiens)


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Danio rerio)


name: acetyl-CoA + 10 AH2 + 2 H(+) + 7 malonyl-CoA + 5 S-adenosyl-L-methionine => 10 A + 7 CO2 + 8 CoA + dehydroprobetaenone I + 6 H2O + 5 S-adenosyl-L-homocysteine


name: 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2 => (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+)


name: Expression of STAT3-upregulated extracellular proteins (Homo sapiens)


name: CHEK2 is recruited to DNA DSBs (Mus musculus)


name: WNTs are secreted in exosomes (Canis familiaris)


name: (3beta,5alpha,17beta)-3-hydroxy-androstan-17-yl sulfate + NADP(+) => 5alpha-dihydrotestosterone sulfate + H(+) + NADPH


name: Glucagon-like Peptide 1 is secreted from intestinal L cells (Gallus gallus)


name: a 4-hydroxynonenal + H(+) + NADPH => a 4-hydroxynonen-1-ol + NADP(+)


name: Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Xenopus tropicalis)


name: RET tyrosine phosphorylation (Sus scrofa)


name: alpha-Fuc-(1->2)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-Glc + an N-acyl-sphingoid base => a ganglioside Fuc-GM1 + H2O


name: Formation Of Bloc-1 Complex (Sus scrofa)


name: Phosphorylation of CARMA1 by PKC-theta (Rattus norvegicus)


name: Activated JAK1 binds RAF1 (Rattus norvegicus)


name: Ribosomal scanning  (Dictyostelium discoideum)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Drosophila melanogaster)


name: Expression of SOX17 in definitive endoderm (Homo sapiens)


name: ADP + H(+) + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] => ATP + N(6)-(D-psicosyl)-L-lysyl-[protein]


name: Ral-GDS binds to Ras-GTP (Xenopus tropicalis)


name: ATG10 dissociates from ATG12:ATG5 (Bos taurus)


name: Recruitment of TBK1/IKK epsilon complex to TANK:TRAF6 (Homo sapiens)


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + NADP(+) + phosphate = [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + H(+) + NADPH


name: "[amino-group carrier protein]-5-phospho-L-glutamate reductase"


name: PAKs autophosphorylate (Caenorhabditis elegans)


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Homo sapiens)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Plasmodium falciparum)


name: Interaction of APS and p-KIT (Rattus norvegicus)


name: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 => A + a 3-demethylubiquinol + H2O


name: delayed rectifier potassium channel activity


name: Mitochondrial FPGS-1 transforms THF to THFPG (Sus scrofa)


name: Formation of ERCC1:XPF heterodimeric complex (Dictyostelium discoideum)


name: AH2 + cob(III)alamin => A + cob(I)alamin + 2 H(+)


name: 3-phenylpropanoate + ATP + H(+) + NADPH => 3-phenylpropanal + AMP + diphosphate + NADP(+)


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Canis familiaris)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Canis familiaris)


name: an S-substituted glutathione(in) + ATP + H2O => ADP + an S-substituted glutathione(out) + H(+) + phosphate


name: 4-sulfobenzoate + NADH + O2 => 3,4-dihydroxybenzoate + NAD(+) + sulfite


name: 2-oxoglutarate + L-valine => 3-methyl-2-oxobutanoate + L-glutamate


name: 24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase] = 32-hydroxy-24,25-dihydrolanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CST complex formation (Rattus norvegicus)


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Dictyostelium discoideum)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Bos taurus)


name: Hv1 Mediated H+ Permeability (Gallus gallus)


name: p-6Y-SYK phosphorylates BLNK (SLP65) (Rattus norvegicus)


name: ITPA hydrolyses XTP to XMP (Dictyostelium discoideum)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Mus musculus)


name: D-glucurono-3,6-lactone + H2O = D-glucuronate + H(+)


name: GLI3R translocates to the nucleus (Drosophila melanogaster)


name: (3R)-hydroxy-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA <=> (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H2O


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Mus musculus)


name: ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate + H2O => acetate + ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Drosophila melanogaster)


name: Fusion of late-endosome derived vesicles at the TGN (Bos taurus)


name: Interaction and oligomerization of MALT1 to Bcl10 (Gallus gallus)


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Sus scrofa)


name: 3 2,3-dihydroxybenzoate + 6 ATP + 3 L-serine <=> 6 AMP + 6 diphosphate + enterobactin + 4 H(+)


name: PKC phosphorylates NFE2L2 (Homo sapiens)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Mus musculus)


name: rRNA (guanine) methyltransferase activity


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Drosophila melanogaster)


name: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: benzaldehyde dehydrogenase (NADP+) activity


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-glycerol <=> 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: Hydrolysis of phosphatidylcholine (Schizosaccharomyces pombe)


name: SUMOylation of RXRA with SUMO1 (Rattus norvegicus)


name: H2O + NADP(+) + penigequinolone B => H(+) + NADPH + yaequinolone D


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Homo sapiens)


name: Phosphorylation of SHC1 by ERBB4 homodimers (Mus musculus)


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Mus musculus)


name: SARS-CoV-2 nsp16 binds to U1 snRNA (Homo sapiens)


name: NLK phosphorylates TCF/LEF (Caenorhabditis elegans)


name: HTRA2 degrades APP (Amyloid-beta precursor protein) (Bos taurus)


name: "diadenosine hexaphosphate hydrolase (ATP-forming)"


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphate + ADP + H(+) => 1,2-ditetradecanoyl-sn-glycerol + ATP


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Canis familiaris)


name: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O => 2-formylglutarate + NH4(+)


name: 14-demethyleburicol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 32-oxoeburicol + O2 + reduced [NADPH--hemoprotein reductase]


name: 2,4-dinitroanisole + H2O = 2,4-dinitrophenol + H(+) + methanol


name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 (Mus musculus)


name: ATP + CoA + deoxycholate <=> AMP + deoxycholoyl-CoA + diphosphate


name: 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: (+-)-pavine + S-adenosyl-L-methionine = H(+) + N-methylpavine + S-adenosyl-L-homocysteine


name: (R)-carnitine + 2,6-dimethylheptanoyl-CoA => CoA + O-2,6-dimethylheptanoyl-(R)-carnitine


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Canis familiaris)


name: GADD45A gene expression is stimulated by FOXO3,FOXO4,(FOXO1) (Homo sapiens)


name: eicosanoyl-CoA + 3 H(+) + 3 malonyl-CoA => 4-hydroxy-6-(2-oxohenicosyl)pyran-2-one + 3 CO2 + 4 CoA


name: H2O + neryl diphosphate => diphosphate + nerol


name: an N(1)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine => an adenosine in tRNA + S-adenosyl-L-methionine


name: Exocytosis of azurophil granule lumen proteins (Plasmodium falciparum)


name: IDO2 dioxygenates L-Trp to NFK (Homo sapiens)


name: Activation of RAC1 by VAV2/3 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine <=> a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline


name: ULK1 phosphorylates RIPK1 at S357 (Canis familiaris)


name: NIK autophosphorylates on T559 (Saccharomyces cerevisiae)


name: ferruginol + O2 + reduced [NADPH--hemoprotein reductase] = 11-hydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: MAPK4,6 translocate to the cytoplasm (Schizosaccharomyces pombe)


name: H2O + L-isoleucine-(+)-12-hydroxy-7-isojasmonate => L-isoleucine + tuberonate


name: (3S,5S)-carbapenam-3-caboxylate + AMP + diphosphate + H(+) => (2S,5S)-5-carboxymethylproline + ATP


name: S1P hydrolyzes SREBP1A,1C,2 (Xenopus tropicalis)


name: 2 (S)-lactate(in) + prostaglandin E2(out) = 2 (S)-lactate(out) + prostaglandin E2(in)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Sus scrofa)


name: Glucagon:GCGR mediates GTP-GDP exchange (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a globoside GalGb4Cer + CMP-N-acetyl-beta-neuraminate <=> a globoside MSGG + CMP + H(+)


name: ADP + H(+) + O-phospho-L-threonine => ATP + L-threonine


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Mus musculus)


name: (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate


name: CSNK1A1 phosphorylates nucleoprotein (Homo sapiens)


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Sus scrofa)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Gallus gallus)


name: glycerol + NADP(+) = D-glyceraldehyde + H(+) + NADPH


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 <=> CO2 + cylindrospermopsin + succinate


name: 3 O2 + quiannulatene + 3 reduced [NADPH--hemoprotein reductase] <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + quiannulatate


name: CoA + O-(9Z)-tetradecenoyl-(R)-carnitine => (9Z)-tetradecenoyl-CoA + (R)-carnitine


name: Defects in F8 A2 domain accelerate dissociation of the A2 domain (Homo sapiens)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Danio rerio)


name: RAB43:GTP binds USP8NL (Plasmodium falciparum)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Rattus norvegicus)


name: CoA + ethyl benzoate => benzoyl-CoA + ethanol


name: Arachidonic acid is oxidised to PGG2 by PTGS2 (Mus musculus)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Homo sapiens)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: H(+)(in) + sarcosine(in) = H(+)(out) + sarcosine(out)


name: an N-(acyl)-sphingosylphosphocholine(in) = an N-(acyl)-sphingosylphosphocholine(out)


name: a uridine in rRNA = a pseudouridine in rRNA


name: D-ribulose 5-phosphate <=> D-xylulose 5-phosphate


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Mus musculus)


name: AGO1,2:small RNA complexes interact with chromatin (Drosophila melanogaster)


name: SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Homo sapiens)


name: alpha-methyl-acetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Xenopus tropicalis)


name: nucleobase-containing compound transmembrane transporter activity


name: H2O + N-dodecanoylsphing-4-enine => dodecanoate + sphing-4-enine


name: Conversion of PA into DAG by PAP-1 (Xenopus tropicalis)


name: a very long-chain fatty acyl-CoA + acetyl-CoA <=> a very-long-chain 3-oxoacyl-CoA + CoA


name: rifamycin SV ortho-naphthoquinone carboxamide => rifamycin SV para-naphthoquinone carboxamide


name: chloride + L-tyrosine + NADP(+) = 3-chloro-L-tyrosine + NADPH


name: H(+)(out) + L-arabinose(in) <=> H(+)(in) + L-arabinose(out)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 2 O2 <=> 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine


name: H(+) + rebaudioside E + UDP => stevioside + UDP-alpha-D-glucose


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Xenopus tropicalis)


name: NAGLU hydrolyses heparan chain(2) (Homo sapiens)


name: Unwinding DNA for the nascent transcript (Drosophila melanogaster)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Canis familiaris)


name: (S)-malate(in) + malonate(out) => (S)-malate(out) + malonate(in)


name: hexadecanoyl-CoA + hexadecasphinganine <=> CoA + H(+) + N-hexadecanoylhexadecasphinganine


name: 15-methylhexadecasphing-4-enine + a fatty acyl-CoA <=> CoA + H(+) + N-acyl-15-methylhexadecasphing-4-enine


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Dictyostelium discoideum)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Bos taurus)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Xenopus tropicalis)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Sus scrofa)


name: 4-hydroxybenzoate + pyruvate => chorismate


name: 3 H(+) + 2 NADH + UDP-N-acetyl-alpha-D-mannosaminouronate => H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-mannosamine


name: USP17L2 deubiquitinates RCE1 (Saccharomyces cerevisiae)


name: Transfer of ubiquitin from E1 to E2 (Bos taurus)


name: H2O + N(6)-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein] <=> H(+) + L-lysyl-[protein] + lactate


name: H(+) + L-tryptophan + O2 => 3-indoleglycolaldehyde + CO2 + NH4(+)


name: Phosphorylated STAT5 is released (Homo sapiens)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Rattus norvegicus)


name: butanoyl-CoA + O2 <=> (2E)-butenoyl-CoA + H2O2


name: ATP + H2O + pyruvate => AMP + 2 H(+) + phosphate + phosphoenolpyruvate


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate => (2E)-geranyl diphosphate + 3 isopentenyl diphosphate


name: Activation of Protein Kinase C novel isoforms (Schizosaccharomyces pombe)


name: L-alanine(out) + Na(+)(out) => L-alanine(in) + Na(+)(in)


name: 2,4-dinitrotoluene + NADH + O2 = 4-methyl-5-nitrocatechol + NAD(+) + nitrite


name: TRPA1 tetramer binds TRPA1 antagonists (Saccharomyces cerevisiae)


name: KCNJs transport K+ from the extracellular region to cytosol (Canis familiaris)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Drosophila melanogaster)


name: IQGAPs bind CALM1 (Schizosaccharomyces pombe)


name: pH-gated monoatomic ion channel activity


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-mannose 1-phosphate <=> (2R)-3-phosphoglycerate + alpha-D-mannose 1,6-bisphosphate + H(+)


name: Collagen type XXV ectomain shedding (Gallus gallus)


name: K63polyUb-IRAK1 dissociates (Caenorhabditis elegans)


name: TYSND1 cleaves TYSND1 (Dictyostelium discoideum)


name: NEU3 hydrolyzes Neu5Ac from glycoconjugates (Canis familiaris)


name: Release of Cytochrome c from mitochondria (Xenopus tropicalis)


name: beta-D-Gal-(1<->1')-Cer + UDP-alpha-D-galactose => alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer + H(+) + UDP


name: CoA + H(+) + N-acetyl-D-aspartate => acetyl-CoA + D-aspartate


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Danio rerio)


name: Thrombin-activated PARs:Gq (active) dissociate (Mus musculus)


name: 3,6-anhydro-alpha-L-galactopyranose + H2O + NADP(+) <=> 3,6-anhydro-L-galactonate + 2 H(+) + NADPH


name: a 5-methyluridine in mRNA + H(+) + S-adenosyl-L-homocysteine => a uridine in mRNA + S-adenosyl-L-methionine


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Dictyostelium discoideum)


name: (+)-5-epi-aristolochene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = capsidiol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADH + pyridoxal => NAD(+) + pyridoxine


name: (8S)-annullatin E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-hydroxymethyl-3-pentylphenol + O2 + reduced [NADPH--hemoprotein reductase]


name: RNA demethylases demethylate N6-methyladenosine RNA (Sus scrofa)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Homo sapiens)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Bos taurus)


name: p-S92,203-BRF1 binds 14-3-3 (Xenopus tropicalis)


name: 1,2,3-trihydroxybenzene + CO2 => 3,4,5-trihydroxybenzoate + H(+)


name: Activation of p38 MAPK (Xenopus tropicalis)


name: H2O + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose => UDP-N-acetyl-alpha-D-glucosamine


name: Collagen type X degradation by MMP1,2 (Homo sapiens)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10-methylenetetrahydromethanopterin + H(+)


name: CGRP receptor can bind calcitonin gene-related peptides (Bos taurus)


name: p-coumaroyltriacetic acid lactone synthase activity


name: NEXT2 is cleaved to produce NICD2 (Homo sapiens)


name: SFTPA/SFTPD binds TLR2:TLR1 (Sus scrofa)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 4beta-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SUMOylation of UBE2I with SUMO1 (Gallus gallus)


name: Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA (Xenopus tropicalis)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Mus musculus)


name: Ubiquitinated and phosphorylated ARM binds to and is degraded by the proteasome complex (Drosophila melanogaster)


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Schizosaccharomyces pombe)


name: Parenchymal atROL translocates to HSCs (Danio rerio)


name: SMG6 hydrolyzes mRNA with premature termination codon (Schizosaccharomyces pombe)


name: H2O + NADP(+) + testosterone acetate => H(+) + NADPH + O2 + progesterone


name: RAB31 GEFs exchange GTP for GDP on RAB31 (Bos taurus)


name: ATP + glycine + holo-[peptidyl-carrier protein] => AMP + diphosphate + glycyl-[peptidyl-carrier protein]


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + CoA => 1-O-alkyl-sn-glycero-3-phosphate + an acyl-CoA


name: a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)


name: Bitter compound binds bitter taste receptor (TAS2R) (Sus scrofa)


name: ent-cassa-12,15-diene + O2 + reduced [NADPH--hemoprotein reductase] = ent-11beta-hydroxycassa-12,15-diene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of Pol zeta complex (Mus musculus)


name: L-glutamate + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose => 2-oxoglutarate + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine


name: (1Z,2S)-2-methylbutanal oxime <=> (2S)-2-methylbutanenitrile + H2O


name: Activation of ATP sensitive Potassium channels in muscle cells (Gallus gallus)


name: (S)-2,3-diaminopropanoate + ATP + citrate => 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + AMP + diphosphate


name: L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] => H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu)


name: a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: GTP + UTP = 3',3'-cGMP-UMP + 2 diphosphate


name: H2O + N(6)-decanoyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-decanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: RNF181 binds BCL10 and Ubiquitin:E2 (Bos taurus)


name: Interaction of nephrin with adherens junction-associated proteins (Homo sapiens)


name: 2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine => 2 H(+) + N(4)-bis(aminopropyl)spermidine + 2 S-methyl-5'-thioadenosine


name: Exocytosis of secretory granule lumen proteins (Plasmodium falciparum)


name: tRNA pseudouridine(55) synthase activity


name: N-acetylation of serotonin (Mus musculus)


name: POLD,POLE binds deISGylated PCNA after TLS (Drosophila melanogaster)


name: FAR2 reduces PalmCoA to HXOL (Danio rerio)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Rattus norvegicus)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + holo-[ACP] => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + tetradecanoyl-[ACP]


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Mus musculus)


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)


name: cytochrome-b5 reductase activity, acting on NADH


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: PXLP-K333-GADL1 decarboxylates CSA to HTAU (Canis familiaris)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Mus musculus)


name: AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Mus musculus)


name: PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex (Sus scrofa)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + O2 <=> an (E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amine + H(+) + H2O2


name: H(+) + NADH + phosphonoacetaldehyde => 2-hydroxyethylphosphonate + NAD(+)


name: CYLD deubiquitinates NEMO (Canis familiaris)


name: (3R)-hydroxy-4-methylpentanoyl-[ACP] + NADP(+) => 4-methyl-3-oxopentanoyl-[ACP] + H(+) + NADPH


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Mus musculus)


name: 3,4-dihydroxybenzoate + ATP + holo-[aryl-carrier protein] <=> 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate


name: 3-methyl-(2E)-glutaconyl-CoA + H2O => (3S)-hydroxy-3-methylglutaryl-CoA


name: 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX => coproporphyrinogen III + 2 S-adenosyl-L-methionine


name: cAMP hydrolysis by Cam-PDE 1 (Gallus gallus)


name: benzylamine + H2O + NAD(+) <=> benzaldehyde + H(+) + NADH + NH4(+)


name: H2O + monomethyl sulfate = H(+) + methanol + sulfate


name: [thioredoxin]-dithiol + S-sulfanyl-L-cysteinyl-[protein] => [thioredoxin]-disulfide + H(+) + hydrogen sulfide + L-cysteinyl-[protein]


name: beta-D-glucose + genistein => genistein 7-O-beta-D-glucoside + H2O


name: a ubiquinone + H(+) + NADH = a ubiquinol + NAD(+)


name: CoA + S-octanoyl-L-cysteinyl-[PqsC protein] => L-cysteinyl-[PqsC protein] + octanoyl-CoA


name: USP44 deubiquitinates CDC20 (Xenopus tropicalis)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O <=> (S)-2-amino-6-oxoheptanedioate


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: The UDP/CysLT (P2Y17) receptor can bind UTP (Bos taurus)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: (R)-carnitine + hexadecanoyl-CoA <=> CoA + O-hexadecanoyl-(R)-carnitine


name: aurasperone A + 2 H2O + NADP(+) => H(+) + NADPH + O2 + 2 rubrofusarin B


name: RHOJ GEFs activate RHOJ (Dictyostelium discoideum)


name: glycyl-L-lysine(out) + 2 H(+)(out) = glycyl-L-lysine(in) + 2 H(+)(in)


name: phycoerythrobilin-L-cysteinyl(84)-[C-phycoerythrin alpha-subunit] = (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[C-phycoerythrin alpha-subunit]


name: PTGS1 dimer binds PTGS1 Inhibitors (Bos taurus)


name: ATP + 2 H2O => AMP + 2 H(+) + 2 phosphate


name: SNAI2 binds CDH1 gene promoter (Homo sapiens)


name: TGFBR2 phosphorylates TGFBR1 (Canis familiaris)


name: TBC1D20 binds RAB1:GTP (Saccharomyces cerevisiae)


name: NMDAR binds PSD-95 subfamily members (Homo sapiens)


name: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) => 5-amino-6-(D-ribitylamino)uracil + riboflavin


name: 5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Xenopus tropicalis)


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate => 13-oxo-(9Z,11E)-octadecadienoate + H2O


name: RAD51B:RAD51C binds single-stranded DNA (Sus scrofa)


name: Autocatalytic activation of MMP7 (Gallus gallus)


name: AH2 + cremeomycin => 2-hydroxy-4-methoxybenzoate + A + N2


name: Activated FGFR2 phosphorylates PPTN11 (Sus scrofa)


name: SHC1 phosphorylation by phosphorylated EGFR (Bos taurus)


name: cytidine + H(+) + H2O => NH4(+) + uridine


name: Reduction of desmosterol to cholesterol (Caenorhabditis elegans)


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Danio rerio)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Drosophila melanogaster)


name: KPNA2 translocates NBN to the nucleus (Bos taurus)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr) => ATP + L-threonine + tRNA(Thr)


name: ADP + H(+) + phosphate + pravastatin(out) => ATP + H2O + pravastatin(in)


name: acetoacetyl-CoA + CO2 + CoA => acetyl-CoA + H(+) + malonyl-CoA


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoate + A + H2O


name: RHOD binds effectors at the mitochondrial outer membrane (Mus musculus)


name: Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) (Sus scrofa)


name: Canonical WNT signaling through the atypical receptor RYK (Drosophila melanogaster)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Rattus norvegicus)


name: ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] => ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate


name: Prolysyl oxidase activation (Canis familiaris)


name: itaconate + L-cysteinyl-[protein] <=> S-(2,3-dicarboxypropyl)-L-cysteinyl-[protein]


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Drosophila melanogaster)


name: LGI3 binds ADAM22,23,synatxin1 (Mus musculus)


name: MATEs mediate extrusion of xenobiotics (Mus musculus)


name: FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Rattus norvegicus)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Mus musculus)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)


name: PLK1 hyperphosphorylates Condensin II complex (Danio rerio)


name: RIP3 binds TRIF to mediate necroptosis (Canis familiaris)


name: [collagen]-(5R)-5-hydroxy-L-lysyl-N-S-L-methionyl-[collagen] + bromide + H(+) + H2O => (5R)-5-hydroxy-L-lysyl-[collagen] + hypobromite + L-methionyl-[collagen]


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Drosophila melanogaster)


name: RHOC GAPs stimulate RHOC GTPase activity (Canis familiaris)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)


name: Extracellular BTD hydrolyses BCTN (Sus scrofa)


name: 4-sulfobenzoate + 2 H(+) + NADH => 4-formylbenzenesulfonate + H2O + NAD(+)


name: Endocytosis of TGFBR3:ARRB complex (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-glycerol + H(+)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H(+) + 3 NADH + 3 O2 = 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 4 H2O + 3 NAD(+)


name: beta-D-fructose 1-phosphate + methylglyoxal => 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + D-glyceraldehyde


name: ATP + CoA + heptadecanoate => AMP + diphosphate + heptadecanoyl-CoA


name: PTPN22 dissociates from CSK (Canis familiaris)


name: Epsin family proteins bind ubiquitinated cargo (Canis familiaris)


name: p-PKR dimer phosphorylates CDK1 (Homo sapiens)


name: a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] = a (7R,8R)-7,8-dihydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + H(+) + H2O + oxidized [flavodoxin]


name: HTR1 and 5A receptors can bind serotonin (Canis familiaris)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Homo sapiens)


name: 1-hexadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O => 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + 10-hydroxyoctadecanoate + H(+)


name: PITPNM1,2,3 exchange PI for PA (Canis familiaris)


name: NID1 degradation by MMP19 (Homo sapiens)


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Canis familiaris)


name: REV1 inserts dCMP opposite to AP sites in DNA (Rattus norvegicus)


name: Formation of MSH2:MSH6 Complex (Sus scrofa)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Homo sapiens)


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Xenopus tropicalis)


name: ADP(out) + ATP(in) => ADP(in) + ATP(out)


name: Association of procollagen type XXII (Canis familiaris)


name: 3-diazo-4-hydroxybenzoate + AMP + diphosphate + H2O => 3-amino-4-hydroxybenzoate + ATP + H(+) + nitrite


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine = 1,3,3'-tri-O-methyl-4alpha-mannobiose + H(+) + S-adenosyl-L-homocysteine


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Schizosaccharomyces pombe)


name: SLC12A3 binds SLC12A3 inhibitors (Homo sapiens)


name: GTP + streptomycin = 6-O-guanylylstreptomycin + diphosphate


name: alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP => N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Homo sapiens)


name: NFE2L2 translocates from cytosol to nucleoplasm (Gallus gallus)


name: (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one => (3R)-3-isopropenyl-6-oxoheptanoate + H(+)


name: 4-nitrophenol + H(+) + NADPH + O2 = 4-nitrocatechol + H2O + NADP(+)


name: 2-formylglutarate + NH4(+) => 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O


name: diphosphate + viridiflorene => (2E,6E)-farnesyl diphosphate


name: diphosphate + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] => GTP + L-histidyl-[RNA ligase]


name: L-methionine transmembrane transporter activity


name: GCHFR binds to GCH1 and negatively regulates its activity (Homo sapiens)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Canis familiaris)


name: methanetellurite + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + tellurite


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Bos taurus)


name: SLC46A1 transports FOLA from extracellular region to cytosol (Bos taurus)


name: acetyl-CoA + 4 H(+) + 6 malonyl-CoA = 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + 6 CO2 + 7 CoA + H2O


name: L-Glutamate loading of synaptic vesicle (Danio rerio)


name: 2 H2O + 3 NADP(+) + NH4(+) = 5 H(+) + 3 NADPH + nitrite


name: cytidine(62) in tRNA(Asp) + S-adenosyl-L-methionine <=> 5-methylcytidine(62) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)


name: glycoursodeoxycholate(out) + 2 Na(+)(out) = glycoursodeoxycholate(in) + 2 Na(+)(in)


name: TRPA1 tetramer binds TRPA1 antagonists (Gallus gallus)


name: 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: a neolactoside IV(3)-alpha-NeuGc-nLc4Cer + UDP-N-acetyl-alpha-D-galactosamine = a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer + H(+) + UDP


name: H2O + presqualene phosphate <=> phosphate + presqualene alcohol


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Caenorhabditis elegans)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Mus musculus)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Sus scrofa)


name: H(+) + NADPH + O2 + protodeoxyviolaceinate => deoxyviolaceinate + H2O + NADP(+)


name: SIRT1 deacetylates HSF1 (Rattus norvegicus)


name: PXLP-K754-GLDC dimer decarboxylates Gly (Mus musculus)


name: Nectin-2:Nectin 3 trans heterodimer interaction (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycerol + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: CYP51A1 demethylates LNSOL (Danio rerio)


name: INTL1 binds bacterial glycans (Rattus norvegicus)


name: 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + S-adenosyl-L-methionine <=> 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + H(+) + S-adenosyl-L-homocysteine


name: (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H(+) + NADPH = (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + NADP(+)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Sus scrofa)


name: TRAF6 is K63 poly-ubiquitinated (Schizosaccharomyces pombe)


name: NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP (Mus musculus)


name: Interaction of beta-2-microglobulin (B2M) chain with  class I HC (Rattus norvegicus)


name: AMP + diphosphate + H(+) + L-seryl-tRNA(Ser) => ATP + L-serine + tRNA(Ser)


name: L-arabinose transmembrane transporter activity


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Saccharomyces cerevisiae)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Dictyostelium discoideum)


name: a menaquinol + 2 O2 <=> a menaquinone + 2 H(+) + 2 superoxide


name: Kinetochore capture of astral microtubules (Sus scrofa)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: WLS binds WNT ligands in the Golgi (Drosophila melanogaster)


name: acetyl-CoA + N-terminal L-methionyl-L-glutamyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein]


name: TGFBR2 recruits TGFBR1 (Caenorhabditis elegans)


name: Translocation of COP1 from the nucleus to the cytoplasm (Gallus gallus)


name: MUS81 binds EME1, EME2 (Xenopus tropicalis)


name: (20S)-protopanaxatriol + UDP-alpha-D-glucose => (20S)-ginsenoside F1 + H(+) + UDP


name: atRAL is reduced to atROL (Gallus gallus)


name: PPA2A dephosphorylates SPRY2 (Mus musculus)


name: Translocation of p27 to the nucleoplasm (Xenopus tropicalis)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Xenopus tropicalis)


name: (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine <=> 4-(trimethylamino)butanal + glycine


name: Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Mus musculus)


name: B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Xenopus tropicalis)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Danio rerio)


name: 1-pyrroline + H2O2 + NH4(+) => O2 + putrescine


name: Activation of caspase-3 (Rattus norvegicus)


name: 5,10-methylenetetrahydromethanopterin + 2 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)


name: RIPK3 is cleaved by CASP8 (Mus musculus)


name: (3S)-hydroxyhexanoyl-CoA + NAD(+) => 3-oxohexanoyl-CoA + H(+) + NADH


name: 3-dehydro-L-gulonate + NADP(+) = 2,3-dioxo-L-gulonate + H(+) + NADPH


name: (5R)-hydroxy-beta-trans-bergamotene + O2 => (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + H2O


name: 5,6-dihydrouridine(17) in tRNA + NADP(+) = H(+) + NADPH + uridine(17) in tRNA


name: Caspase-mediated cleavage of occludin (Drosophila melanogaster)


name: 2-oxoglutarate + a (2S)-flavan-4-one + O2 <=> a (2R,3R)-dihydroflavonol + CO2 + succinate


name: Phosphorylation of IKK-beta by TAK1 (Sus scrofa)


name: (20S)-ginsenoside Rb1 + 2 H2O <=> (20S)-ginsenoside Rg3 + 2 D-glucose


name: (9Z)-hexadecenoate + CoA + H(+) => (9Z)-hexadecenoyl-CoA + H2O


name: AKAP8L binds MLL1 complex (Mus musculus)


name: NTPDase8 hydrolyzes nucleoside diphosphates (Mus musculus)


name: PKC-delta phosphorylates CARD9 (Sus scrofa)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: L-glutamine(in) + L-serine(out) + Na(+)(in) => L-glutamine(out) + L-serine(in) + Na(+)(out)


name: XDH oxidizes xanthine to form urate (Bos taurus)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Xenopus tropicalis)


name: (2S)-versicolorone + H(+) + NADPH + O2 <=> (3S)-versiconol acetate + H2O + NADP(+)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => beta-geranylfarnesene + diphosphate


name: H2O + N(7)-methyl-GTP => diphosphate + H(+) + N(7)-methyl-GMP


name: N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Bos taurus)


name: E2F6 binds the PRC1 complex (Sus scrofa)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Drosophila melanogaster)


name: (9Z,11E)-octadecadienoate + H2O = 10-hydroxy-(11E)-octadecenoate


name: MTMR14, MTMR3 dephosphorylate PI3P (Schizosaccharomyces pombe)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Mus musculus)


name: Caspase-mediated cleavage of Desmoglein 3 (Homo sapiens)


name: PTPN7 binds p-T,Y-MAPK (Dictyostelium discoideum)


name: 2 cob(II)alamin-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] => 2 cob(I)alamin-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein]


name: E2F6.com-1 complex binds the E2F1 gene promoter (Homo sapiens)


name: FECH binds Fe2+ to PRIN9 to form heme (Schizosaccharomyces pombe)


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Caenorhabditis elegans)


name: PTGS2 dimer oxidises DHA to 13-HDHA (Xenopus tropicalis)


name: H(+) + quercetin 3-O-beta-D-glucoside + UDP => quercetin + UDP-alpha-D-glucose


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-choline <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: 1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O => 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: N-acetylserotonin + S-adenosyl-L-methionine => H(+) + melatonin + S-adenosyl-L-homocysteine


name: Granzyme-B activates BID by cleavage (Xenopus tropicalis)


name: a ganglioside GD1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1balpha  (d18:1(4E)) + CMP + H(+)


name: FGFRL1 dimer binds FGFs (Caenorhabditis elegans)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP


name: EPHB:NMDAR binds TIAM1 (Rattus norvegicus)


name: SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Rattus norvegicus)


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Sus scrofa)


name: H2O + sn-glycero-3-phospho-1D-myo-inositol => 1D-myo-inositol 1-phosphate + glycerol + H(+)


name: H2O + N-eicosanoylglycinate => eicosanoate + glycine


name: Activation of RAC1 by VAV2/3 (Drosophila melanogaster)


name: NADP(+) + octanal => (2E)-octenal + H(+) + NADPH


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN3B (GRIN3B) (Homo sapiens)


name: Monoiodinated tyrosine can be deiodinated (Mus musculus)


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Plasmodium falciparum)


name: KEN dimer represses transcription (Drosophila melanogaster)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Danio rerio)


name: CXADR binds to AMICA1 (Canis familiaris)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Xenopus tropicalis)


name: SUMOylation of PIAS4 with SUMO1 (Saccharomyces cerevisiae)


name: RHOC GAPs stimulate RHOC GTPase activity (Sus scrofa)


name: 2 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + 2 H(+) + O2 => 2 aureusidin 6-O-beta-glucoside + 2 H2O


name: isodeoxycholate + NAD(+) => 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: Mg-protoporphyrin IX + S-adenosyl-L-methionine <=> Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine


name: dimethyl sulfide + S-adenosyl-L-methionine <=> S-adenosyl-L-homocysteine + trimethylsulfonium


name: VAV1 is a GEF for Rho/Rac family GTPases (Mus musculus)


name: a quinone + L-proline => (S)-1-pyrroline-5-carboxylate + a quinol + H(+)


name: D-amino acid transmembrane transporter activity


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Xenopus tropicalis)


name: H2O + indole-3-acetaldehyde + O2 = (indol-3-yl)acetate + H(+) + H2O2


name: 24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: TPI1 isomerizes GA3P to DHAP (Dictyostelium discoideum)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Danio rerio)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Dictyostelium discoideum)


name: benzoyl-CoA + benzyl alcohol => benzyl benzoate + CoA


name: ACO2 isomerizes citrate (Schizosaccharomyces pombe)


name: 4-methylumbelliferone + phenyl sulfate => 4-methylumbelliferone sulfate + phenol


name: Proteasomal clevage of exogenous antigen (Plasmodium falciparum)


name: PKC phosphorylates sphingosine kinase 1 (Schizosaccharomyces pombe)


name: ORC1 translocates to the nucleus (Plasmodium falciparum)


name: SOCS1,3 binds p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 (Homo sapiens)


name: methylarsonous acid + S-adenosyl-L-methionine <=> dimethylarsinate + 2 H(+) + S-adenosyl-L-homocysteine


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Saccharomyces cerevisiae)


name: H(+) + 2 H2O + N(5)-[4-(S-L-cysteinyl-[protein])-5-methyl-1H-imidazol-2-yl]-L-ornithinyl-[protein] => L-arginyl-[protein] + L-cysteinyl-[protein] + methylglyoxal


name: CYP3A4,5 hydroxylates AFB1 to AFQ1 (Bos taurus)


name: Interaction of PECAM-1 and SHP-1 (Mus musculus)


name: (6S)-5,6,7,8-tetrahydrofolate + ATP + formate <=> (6R)-10-formyltetrahydrofolate + ADP + phosphate


name: a cardiolipin + H2O => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)


name: L-pipecolate + O2 => H(+) + H2O2 + L-1-piperideine-6-carboxylate


name: TXLNA (IL14) binds syntaxin4 (Drosophila melanogaster)


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Sus scrofa)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Sus scrofa)


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Bos taurus)


name: p190RhoGAP binds Plexin-B1 (Caenorhabditis elegans)


name: Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Canis familiaris)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Sus scrofa)


name: FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Homo sapiens)


name: MTMR4 binds phosphorylated SMAD2/3 (Drosophila melanogaster)


name: RUNX1 binds PAX5 (BSAP) (Caenorhabditis elegans)


name: RRAGA,B exchanges GDP for GTP (Rattus norvegicus)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Sus scrofa)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 <=> CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate


name: Dopachrome is transformed to DHICA by DCT (Canis familiaris)


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Caenorhabditis elegans)


name: SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Xenopus tropicalis)


name: GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Caenorhabditis elegans)


name: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 => (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O


name: PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Homo sapiens)


name: Activated protein C:PROCR binds F2R (Bos taurus)


name: p-S407-STAT6 is phosphorylated at Tyr641 (Danio rerio)


name: 15,9'-di-cis-phytofluene + a plastoquinol => 15-cis-phytoene + a plastoquinone


name: Initial activation of proMMP3 (Homo sapiens)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Bos taurus)


name: Formation of Cyclin B:Cdc2 complexes (Caenorhabditis elegans)


name: D-serine + H2O + NAD(+) <=> 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: H2O + O2 + spermidine => 4-aminobutanal + H2O2 + propane-1,3-diamine


name: Cargo-carrying vesicles bud from the TGN (Sus scrofa)


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Drosophila melanogaster)


name: aculene D + CO2 + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => asperaculane E + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: p62 recruits an atypical PKC (Rattus norvegicus)


name: a 7(1)-hydroxybacteriochlorophyllide c + H2O + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide c + H(+) + L-methionine


name: atROL binds RBP1 to form RBP1:atROL (Danio rerio)


name: 5,10-methylenetetrahydrosulfopterin + glycine + H2O = L-serine + tetrahydrosulfopterin


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphate + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O


name: nuatigenin + UDP-alpha-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP


name: acetyl-[citrate lyase ACP] + AMP + diphosphate => acetate + ATP + holo-[citrate lyase ACP]


name: Activation of linoleic acid to linoleoyl-CoA (Mus musculus)


name: (8Z,11Z,14Z)-heptadecatrienal + A + H2O = (8Z,11Z,14Z)-heptadecatrienoate + AH2 + H(+)


name: Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)


name: p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 (Sus scrofa)


name: (3E)-decenoyl-CoA + NADP(+) => (2E,4E)-decadienoyl-CoA + H(+) + NADPH


name: (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA (Sus scrofa)


name: factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Canis familiaris)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Mus musculus)


name: a long-chain fatty acyl-AMP + holo-[ACP] <=> a long-chain fatty acyl-[ACP] + AMP + H(+)


name: Formation of dehydro-lysinonorleucine cross-links (Gallus gallus)


name: 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA = 1-butanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: MAT1A multimers transfer Ado from ATP to L-Met (Mus musculus)


name: 5-aminolevulinate + pyruvate <=> 4,5-dioxopentanoate + L-alanine


name: MAOB inhibitors bind MAOB:FAD (Xenopus tropicalis)


name: SMAC binds XIAP:Caspase-3 (Homo sapiens)


name: alpha,alpha-trehalose + H2O <=> alpha-D-glucose + beta-D-glucose


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Gallus gallus)


name: STAT3 binds activated MET receptor (Xenopus tropicalis)


name: AH2 + kynurenate + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + A


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + H2O + 2 oxidized [adrenodoxin]


name: ATP(in) + H2O(in) + Zn(2+)(out) = ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in)


name: Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Rattus norvegicus)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O <=> 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Bos taurus)


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: SLIT2-bound ROBO1 binds MYO9B (Mus musculus)


name: AH2 + O2 + tryptamine = 4-hydroxytryptamine + A + H2O


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Danio rerio)


name: 4 H(+) + 5 malonyl-CoA = 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + 5 CoA + H2O


name: 2,3-dihydroxybenzoyl-5'-AMP + holo-[ACP] = 2,3-dihydroxybenzoyl-[ACP] + AMP + H(+)


name: H(+)(out) + myo-inositol(out) = H(+)(in) + myo-inositol(in)


name: snRNP:Snurportin complex formation (Homo sapiens)


name: Nephrin trans-homophilic interaction (Caenorhabditis elegans)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: cysteine-dependent adenosine diphosphate thiazole synthase activity


name: RFC binding displaces Pol Alpha on the C-strand of the telomere (Gallus gallus)


name: Caspase-mediated cleavage of Z0-2 (Mus musculus)


name: (2E)-glutaconyl-CoA + H2O => (S)-3-hydroxyglutaryl-CoA


name: IGF2BP1 represses translation of MAPK4 mRNA (Homo sapiens)


name: STRA6 transports atROL from extracellular region to cytosol (Xenopus tropicalis)


name: Phosphorylation of CRMPs by Cdk5 (Rattus norvegicus)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Caenorhabditis elegans)


name: Joining of adjacent Okazaki fragments (Saccharomyces cerevisiae)


name: ERK1/2 phosphorylates MSK1 (Rattus norvegicus)


name: 4'-hydroxyechinenone + AH2 + O2 => 4',4'-dihydroxyechinenone + A + H2O


name: 2-oxoglutarate + putrescine = 4-aminobutanal + L-glutamate


name: PLK1 phosphorylates FIRMM at S744 (Bos taurus)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA <=> (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: SMURF1/2 dissociates from ub-PTCH1 (Bos taurus)


name: LONP1 binds mitochondrial inner membrane proteins (Homo sapiens)


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Mus musculus)


name: Src activation following P2Y purinoceptor activation (Sus scrofa)


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Mus musculus)


name: TFRC dimer binds 2xholoTF (Rattus norvegicus)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Xenopus tropicalis)


name: Activation of WASP and N-WASP by CDC42 (Homo sapiens)


name: p-CD19:VAV binds PI3K and GRB2 (Canis familiaris)


name: Activated PLC gamma dissociates from the PDGF receptor (Drosophila melanogaster)


name: a 5'-end ribonucleotide-RNA + a ribonucleoside 5'-triphosphate + ATP + H2O = a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + AMP + 2 diphosphate + H(+)


name: chloride(out) + L-threonine(out) + 2 Na(+)(out) <=> chloride(in) + L-threonine(in) + 2 Na(+)(in)


name: Nitrite ion and HNO2 form a conjugated acid-base pair (Homo sapiens)


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Homo sapiens)


name: Dehalogenation of carbon tetrachloride to form a free radical (Dictyostelium discoideum)


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Danio rerio)


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Caenorhabditis elegans)


name: Activation of GRIK3 homomer (Gallus gallus)


name: 24-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase]


name: BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. (Homo sapiens)


name: butanoate(out) + estrone 3-sulfate(in) <=> butanoate(in) + estrone 3-sulfate(out)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Caenorhabditis elegans)


name: Fe(III)-[cytochrome c] + H2O + nitric oxide = Fe(II)-[cytochrome c] + 2 H(+) + nitrite


name: G6PC2 hydrolyzes G6P to form Glc and Pi (islet) (Mus musculus)


name: TRAFs bind RANK:RANKL (Rattus norvegicus)


name: 2xTPK1:Mg2+ phosphorylates THMN (Plasmodium falciparum)


name: Formation of Cyclin A:Cdk2 complexes (Canis familiaris)


name: 9R-hydroperoxy(5Z,7E,11Z,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: Phosphorylation (Ser5) of RNA pol II CTD (Canis familiaris)


name: REV1 binds AP-dsDNA (Plasmodium falciparum)


name: (R)-carnitine(out) + chloride(out) + 2 Na(+)(out) <=> (R)-carnitine(in) + chloride(in) + 2 Na(+)(in)


name: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 <=> CO2 + H(+) + H2O + scopolamine + succinate


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Sus scrofa)


name: a 1,2-diacyl-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine


name: Fe(III)-[cytochrome c] + H2O + nitric oxide => Fe(II)-[cytochrome c] + 2 H(+) + nitrite


name: 3-hydroxytetradecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-(2-hydroxytridecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Homo sapiens)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: EGFR dimerization (Caenorhabditis elegans)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Homo sapiens)


name: Insulin binds the insulin receptor (Bos taurus)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Schizosaccharomyces pombe)


name: Meglitinides bind ABCC8 (Drosophila melanogaster)


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Homo sapiens)


name: BAD displaces tBID from BCL-2 sequestration (Mus musculus)


name: RHOA GAPs stimulate RHOA GTPase activity (Gallus gallus)


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Bos taurus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Canis familiaris)


name: a dicarboxylate(in) + sulfate(out) <=> a dicarboxylate(out) + sulfate(in)


name: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Danio rerio)


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Homo sapiens)


name: Squalene is oxidized to its epoxide (Rattus norvegicus)


name: N-acetyl-D-glucosamine + O2 = H2O2 + N-acetyl-D-glucosamino-1,5-lactone


name: an S-alkyl-L-cysteine => 2-aminoprop-2-enoate + an alkyl thiol


name: (25S)-Delta7-dafachronate + 4 H2O + 3 NADP(+) => 5alpha-cholest-7-en-3-one + 2 H(+) + 3 NADPH + 3 O2


name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression (Danio rerio)


name: RNASEs bind bacterial phospholipids (Rattus norvegicus)


name: [(1->3)-alpha-D-glucosyl](n) + phosphate <=> [(1->3)-alpha-D-glucosyl](n-1) + beta-D-glucose 1-phosphate


name: 7-methylmellein + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 7-carboxymellein + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: a myo-inositol phosphate + H2O = myo-inositol + phosphate


name: 6-hydroxy-L-homoarginine = (S)-2-amino-6-oxohexanoate + guanidine


name: 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA + H2O => 5-methylaminomethyl-2-selenouridine(34) in tRNA + phosphate


name: RAB11A:GTP-containing Golgi vesicles recruit RAB3IP (Homo sapiens)


name: adenosine(in) + H(+)(in) = adenosine(out) + H(+)(out)


name: COPI vesicle uncoating (Canis familiaris)


name: hexadecanoyl-[ACP] + L-lysyl-[protein] <=> H(+) + holo-[ACP] + N(6)-hexadecanoyl-L-lysyl-[protein]


name: 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide => H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+)


name: Nck binds to the active PDGF receptor (Drosophila melanogaster)


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Sus scrofa)


name: PDE5A dimer binds PDE5A inhibitors (Homo sapiens)


name: a 3-demethylubiquinol + S-adenosyl-L-methionine <=> a ubiquinol + H(+) + S-adenosyl-L-homocysteine


name: E-selectin binds E-selectin ligand (Danio rerio)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Dictyostelium discoideum)


name: glycine + pyruvate => glyoxylate + L-alanine


name: Thrombin-activated PARs:Gq (active) dissociate (Gallus gallus)


name: "3'-phosphate/5'-hydroxy nucleic acid ligase"


name: EP300 acetylates histone H2A, H2B, H3, H4 (Canis familiaris)


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Caenorhabditis elegans)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Canis familiaris)


name: Dimerization of FGFR2 ligand-independent mutants (Homo sapiens)


name: spermidine:coumaroyl CoA N-acyltransferase activity


name: Proteolytic degradation of ubiquitinated-Cdc25A (Canis familiaris)


name: 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2 => CO2 + H2O + NAD(+) + naphthalene-1,2-diol


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Schizosaccharomyces pombe)


name: 4-coumaroyl-CoA + H(+) + malonyl-CoA <=> (4-coumaroyl)acetyl-CoA + CO2 + CoA


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Drosophila melanogaster)


name: L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[SCAN] => L-cysteinyl-[SCAN] + S-nitroso-L-cysteinyl-[protein]


name: demethyldeoxyspectinabilin + S-adenosyl-L-methionine <=> deoxyspectinabilin + S-adenosyl-L-homocysteine


name: ALD3A1 oxidises 4HPCP to CXPA (Rattus norvegicus)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Danio rerio)


name: Cleavage of ethenoadenine by MPG glycosylase (Rattus norvegicus)


name: RBP3 regulates atROL taken up by Muller cells (Xenopus tropicalis)


name: sodium-independent organic anion transmembrane transporter activity


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Dictyostelium discoideum)


name: (R)-lipoate + ATP + H(+) = (R)-lipoyl-5'-AMP + diphosphate


name: D-altronate <=> 2-dehydro-3-deoxy-D-gluconate + H2O


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Drosophila melanogaster)


name: 3-methyl-2-oxobutanoate + CoA + NAD(+) <=> 2-methylpropanoyl-CoA + CO2 + NADH


name: FUT3 transfers Fuc to Type 1 DSGG to form dsLeA (Sus scrofa)


name: Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Bos taurus)


name: VLDL translocates from SER lumen to extracellular region (Rattus norvegicus)


name: Interaction of DAP12 and KIR3DS1 (Sus scrofa)


name: ADP + H(+) + O-phospho-L-serine => ATP + L-serine


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Plasmodium falciparum)


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Mus musculus)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Sus scrofa)


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + [thyroglobulin]-3-iodo-L-tyrosine + H2O2 <=> [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Bos taurus)


name: IL4:IL4R:JAK2 binds IL2RG:JAK3 (Mus musculus)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Sus scrofa)


name: pyruvate dehydrogenase (acetyl-transferring) activity


name: 3,4-dihydroxybenzoate + ATP + H(+) = 3,4-dihydroxybenzoyl-5'-AMP + diphosphate


name: PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 (Gallus gallus)


name: 4-acetoxybenzyl alcohol + NAD(+) => 4-acetoxybenzaldehyde + H(+) + NADH


name: cholesterol + NAD(+) => cholest-5-en-3-one + H(+) + NADH


name: 5-(9Z-octadecenoyloxy)-octadecanoate + H2O = (9Z)-octadecenoate + 5-hydroxy-octadecanoate + H(+)


name: 4-phospho-L-aspartate + ADP => ATP + L-aspartate


name: (S)-nicotine + A + H2O = (S)-6-hydroxynicotine + AH2


name: SUMOylation of DDX5 with SUMO1 (Xenopus tropicalis)


name: a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: RRAGC,D exchanges GTP for GDP (Sus scrofa)


name: GMPS dimer transforms 6TXMP to 6TGMP (Caenorhabditis elegans)


name: H2O + mevastatin <=> H(+) + mevinic carboxylate


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + H(+) + phosphoethanolamine


name: CYP2C19 5-hydroxylates omeprazole (Dictyostelium discoideum)


name: Disassembly of SR-BI-bound spherical HDL (Gallus gallus)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Canis familiaris)


name: HCCS inserts heme into cytochrome c (Mus musculus)


name: hydrolase activity, acting on acid anhydrides


name: cholate + L-arginine = H2O + L-arginocholate


name: putrescine + spermidine <=> propane-1,3-diamine + sym-homospermidine


name: N-formimidoyl-L-glutamate => 4-imidazolone-5-propanoate + H2O


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Canis familiaris)


name: Grb7 binds to the active PDGF receptor (Homo sapiens)


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Bos taurus)


name: Activated CIT binds KIF14 and PRC1 (Drosophila melanogaster)


name: ATP + N(8)-citryl-spermidine + spermidine => AMP + diphosphate + H(+) + N(8),N'(8)-citryl-bis(spermidine)


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Mus musculus)


name: Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes (Homo sapiens)


name: 4-guanidinobutanoate + H2O => 4-aminobutanoate + urea


name: an L-alpha-amino acid + CO2 + NH4(+) => an N-carbamoyl-L-alpha-amino acid + 2 H(+) + H2O


name: ME2 tetramer decarboxylates MAL to PYR (Danio rerio)


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Drosophila melanogaster)


name: 2,3-dioctadecanoyl-sn-glycerol + H(+) + octadecanoate => H2O + trioctadecanoylglycerol


name: NADP(+) + sn-glycerol 1-phosphate <=> dihydroxyacetone phosphate + H(+) + NADPH


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Xenopus tropicalis)


name: Movement of clathrin coated vesicles into early endosome (Sus scrofa)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (3E,7E)-dolathalia-3,7,11-triene + diphosphate


name: AXIN is phosphorylated in the destruction complex (Drosophila melanogaster)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Homo sapiens)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Homo sapiens)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Mus musculus)


name: Interaction of SHP1 and KIT (Homo sapiens)


name: HDAC8 deacetylates histones (Plasmodium falciparum)


name: Formation of nonameric complex (Rattus norvegicus)


name: (S)-methioninol + H2O + NAD(+) = 1-hydroxy-4-(methythio)butan-2-one + H(+) + NADH + NH4(+)


name: 3-oxopentanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxypentanoyl-[ACP] + NADP(+)


name: H(+) + N-acetyl-alpha-D-muramate 1-phosphate + UDP = phosphate + UDP-N-acetyl-alpha-D-muramate


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 => N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-taurine


name: H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate <=> 2 GDP + 2 H(+)


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Canis familiaris)


name: PARVB/Affixin interacts with alpha PIX (Gallus gallus)


name: 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Rattus norvegicus)


name: PIAS1 binds p-STAT1 dimer (Caenorhabditis elegans)


name: all-trans-10'-apo-beta-carotenal + O2 => 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + beta-ionone


name: [(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-beta-D-glucosyl](n+1) + H(+) + UDP


name: glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose(al1-4)glucosaminyl-acyl-PI + dolichol phosphate (Mus musculus)


name: a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-alpha-D-glucose <=> a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside + H(+) + UDP


name: TP receptor can bind thromboxane (Sus scrofa)


name: (2E)-decenoyl-CoA + H2O => (3R)-3-hydroxydecanoyl-CoA


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Caenorhabditis elegans)


name: cyclic-di-GMP transmembrane transporter activity


name: 25-hydroxy 3-oxocholestane + AH2 => 3-oxocholestane + A + H2O


name: 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Sus scrofa)


name: CBL recruits CIN85:endophilin to ubiquitinated MET (Sus scrofa)


name: CCND1 binds RUNX3 and displaces EP300 (Rattus norvegicus)


name: L-selenocysteinyl-tRNA(Sec) + phosphate => H(+) + L-seryl-tRNA(Sec) + selenophosphate


name: RHOA:GTP translocates to the ER membrane (Xenopus tropicalis)


name: dimethylallyl diphosphate + phlorisovalerophenone <=> 4-prenylphlorisovalerophenone + diphosphate


name: a 5'-end ribonucleotide-tRNA(His) + ATP + H(+) = a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate


name: dopamine + H2O + O2 => 3,4-dihydroxyphenylacetaldehyde + H2O2 + NH4(+)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Danio rerio)


name: L-glutamate + UDP-beta-L-threo-pentopyranos-4-ulose => 2-oxoglutarate + UDP-4-amino-4-deoxy-beta-L-arabinose


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Mus musculus)


name: 24,25-dihydrolanosterol + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] => 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Drosophila melanogaster)


name: STARD5 binds DCA, LCA (Rattus norvegicus)


name: ME3 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)


name: PGG2 is reduced to PGH2 by PTGS2 (Mus musculus)


name: decanoate + 2 H(+) + NADH => decanal + H2O + NAD(+)


name: ATP + L-serine + tRNA(Ser) <=> AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)


name: L-arginine(in) + L-leucine(out) = L-arginine(out) + L-leucine(in)


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Rattus norvegicus)


name: PEX19:class I PMP binds PEX3 (Bos taurus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Gallus gallus)


name: a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Bos taurus)


name: (2E)-geranial + H(+) + NADH => (2E)-geraniol + NAD(+)


name: MeSeOH is reduced to MeSeH by TXNRD1 (Bos taurus)


name: hydroxymethylbutenyl pyrophosphate reductase activity


name: Caspase-mediated cleavage of E-Cadherin (Danio rerio)


name: LDLR:LDL complex => LDLR + LDL (Bos taurus)


name: ATP + streptomycin = 6-O-adenylylstreptomycin + diphosphate


name: (2E,6E)-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphate


name: CDC42 GDIs block activation of CDC42 (Bos taurus)


name: H2O + O-acyl-(R)-carnitine = (R)-carnitine + a fatty acid + H(+)


name: PRODH oxidises L-Pro to 1PYR-5COOH (Caenorhabditis elegans)


name: 3-oxo-(21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + NADP(+)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Bos taurus)


name: GBF1 recruits ARF:GDP to the ERGIC (Dictyostelium discoideum)


name: Loading of antigenic peptides (Bos taurus)


name: 4-chlorobenzoate + H2O => 4-hydroxybenzoate + chloride + H(+)


name: 3-{[(1S,2R,4aR,6R,8aS)-2-(but-2-en-2-yl)-3,4a,6-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-5-(2-methylpropyl)-2,3-dihydro-1H-pyrrol-2-one + O2 => H2O2 + myceliothermophin E


name: PE is methylated to PC by PEMT (Xenopus tropicalis)


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H(+) + UDP => 1D-myo-inositol 3-phosphate + UDP-N-acetyl-alpha-D-glucosamine


name: (9Z)-octadecenamide + glyoxylate => N-(9Z-octadecenoyl)-(2S)-hydroxyglycine


name: 3-hydroxy-2-methylpropanoate + NAD(+) => 2-methyl-3-oxopropanoate + H(+) + NADH


name: butanoate + NAD(+) => (2E)-2-butenoate + H(+) + NADH


name: D-lysopine + H2O + NADP(+) => H(+) + L-lysine + NADPH + pyruvate


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Homo sapiens)


name: 1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = 1,2-dibutyryl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: PDE5A dimer binds PDE5A inhibitors (Mus musculus)


name: 5-methylcytidine(61) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine => cytidine(61) in tRNA(Asp) + S-adenosyl-L-methionine


name: AH2 + O2 + protoaustinoid B = A + H2O + preaustinoid A


name: dimethylamine + methyl-Co(III)-[trimethylamine-specific corrinoid protein] => Co(I)-[trimethylamine-specific corrinoid protein] + H(+) + trimethylamine


name: pelargonidin 3-O-beta-D-glucoside + UDP => pelargonidin + UDP-alpha-D-glucose


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Rattus norvegicus)


name: NUMB:ITCH ubiquitinates GLI1 (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => 8-hydroxycopalyl diphosphate


name: CCPs deglutamylate tubulin (Homo sapiens)


name: SUMOylation of TOP1 with SUMO1 (Gallus gallus)


name: GLUT14 (SLC2A14) tetramer transports Glc from extracellular region to cytosol (Danio rerio)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Drosophila melanogaster)


name: (S)-eriodictyol + beta-D-glucose => eriodictyol-7-O-beta-D-glucoside + H2O


name: p-Y693-STAT4 dimerizes (Drosophila melanogaster)


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Homo sapiens)


name: (+)-secoisolariciresinol + NADP(+) = (-)-lariciresinol + H(+) + NADPH


name: 24,25-dihydrolanosterol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + gibberellin A20 + O2 <=> CO2 + gibberellin A1 + succinate


name: General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Rattus norvegicus)


name: 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin] => glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine


name: a fatty acyl-CoA + sphinga-4E,14Z-dienine => an N-acyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: SUMOylation of HDAC2 with SUMO1 (Xenopus tropicalis)


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Drosophila melanogaster)


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Sus scrofa)


name: O2 + quinine + reduced [NADPH--hemoprotein reductase] => 3-hydroxyquinine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 19 H(+) + holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine => 9 CO2 + 9 CoA + dihydromonacolin L-[lovastatin nonaketide synthase] + 6 H2O + 11 NADP(+) + S-adenosyl-L-homocysteine


name: (S)-cis-N-methyltetrahydropalmatine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + muramine + oxidized [NADPH--hemoprotein reductase]


name: thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators (Gallus gallus)


name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Dictyostelium discoideum)


name: L-thiazolidine-2-carboxylate + NADP(+) => Delta(2)-thiazoline-2-carboxylate + 2 H(+) + NADPH


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 <=> 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: 2-oxoglutarate + asnovolin A + 2 O2 <=> CO2 + fumigatonoid A + succinate


name: VENTX binds the CDKN2A gene (Homo sapiens)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Canis familiaris)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Bos taurus)


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Drosophila melanogaster)


name: CO2 + pentadecane => H(+) + hexadecanoate + hnu


name: 5alpha-androst-1-ene-3,17-dione + A + H2O = 5alpha-androstan-1,3,17-trione + AH2


name: Orc1 is phosphorylated by cyclin A/CDK2 (Mus musculus)


name: VWF multimer binds to collagen type I (Xenopus tropicalis)


name: guanine + NAD(+) = H(+) + N(2)-(ADP-D-ribosyl)-guanine + nicotinamide


name: 2-acyl LPC is acylated to PC by LPCAT (Bos taurus)


name: Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (Canis familiaris)


name: 3 a ubiquinol(in) + 2 H(+)(out) + nitrite(out) <=> 3 a ubiquinone(in) + 2 H2O(out) + NH4(+)(out)


name: USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Rattus norvegicus)


name: IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Gallus gallus)


name: 2 (E)-4-coumaroyl-CoA + spermidine => 2 CoA + 2 H(+) + N(1),N(8)-bis(coumaroyl)-spermidine


name: Addition of galactose by beta 4-galactosyltransferases (Xenopus tropicalis)


name: ADP-D-ribose + phosphate => ADP-alpha-D-ribose 1''-phosphate + H2O


name: 4-nitrophenol + H(+) + NADPH + O2 => 4-nitrocatechol + H2O + NADP(+)


name: WIPIs bind PI3P (Schizosaccharomyces pombe)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-(9Z-octadecaenoyl)-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Mus musculus)


name: HSF1-mediated gene expression (Schizosaccharomyces pombe)


name: Collagen type XVI degradation by MMP9 (Homo sapiens)


name: Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Drosophila melanogaster)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Sus scrofa)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Sus scrofa)


name: 5alpha-androst-1-ene-3,17-dione + H2O <=> 1-hydroxy-5alpha-androstan-3,17-dione


name: Release of L-Glutamate at the synapse (Bos taurus)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 <=> 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) <=> 5,7-dihydroxy-4-methylphthalide + H2O


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Xenopus tropicalis)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Canis familiaris)


name: NSF and SNAPs bind cis-SNARE complex (Rattus norvegicus)


name: D-tryptophanyl-tRNA(Trp) + H2O => D-tryptophan + tRNA(Trp)


name: high-density lipoprotein particle binding


name: epiandrosterone 3-sulfate(out) + 2 Na(+)(out) <=> epiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: 2-methylhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: PI is exchanged with PC by PITPNB (Sus scrofa)


name: BRF1 Complex recruits RNA degradation activities (Bos taurus)


name: GRK1,4,7 phosphorylate MII to p-MII (Bos taurus)


name: Separation of elongating transcript from template (Sus scrofa)


name: a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GM2 + H(+) + UDP


name: EPH receptors autophosphorylate (Danio rerio)


name: chloride(in) + 2 hydrogencarbonate(out) + K(+)(out) => chloride(out) + 2 hydrogencarbonate(in) + K(+)(in)


name: Pink1 is recruited from the cytoplasm to the mitochondria (Sus scrofa)


name: Expression of MSX1 in the neural plate border (Homo sapiens)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Homo sapiens)


name: 2xTRAP hydrolyzes FMN to RIB (Sus scrofa)


name: 2-oxoglutarate + UDP-4-amino-4-deoxy-beta-L-arabinose = L-glutamate + UDP-beta-L-threo-pentopyranos-4-ulose


name: NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Xenopus tropicalis)


name: TPMT transfers CH3 from AdoMet to 6MP (Xenopus tropicalis)


name: IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Canis familiaris)


name: acetyl-CoA + D-glutamate <=> CoA + H(+) + N-acetyl-D-glutamate


name: 2-methoxy-6-(all-trans-heptaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine => 3-(all-trans-heptaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine


name: 3-methylundecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: Receptor FFAR3 binds carboxylates (Canis familiaris)


name: cytokinin riboside 5'-monophosphate phosphoribohydrolase activity


name: AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp) => ATP + L-tryptophan + tRNA(Trp)


name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Drosophila melanogaster)


name: (2S,3S)-hydroxyarginine => (2S,3R)-capreomycidine + H2O


name: ATP + L-glutamate + methylamine => ADP + H(+) + N(5)-methyl-L-glutamine + phosphate


name: estrone + H(+) + sulfate => estrone 3-sulfate + H2O


name: (5S)-hydroperoxy-(12S)-hydroxy-(6E,8Z,10E,14Z)-eicosatetraenoate => (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2


name: RHOA binds effectors at the plasma membrane (Danio rerio)


name: Squalene is oxidized to its epoxide (Sus scrofa)


name: [DsrC protein]-dithiol + 3 H(+) + NADH + sulfite => [DsrC protein]-trisulfide + 3 H2O + NAD(+)


name: 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine => pyridine + thiamine


name: IRE1 dimer autophosphorylates (Drosophila melanogaster)


name: L-asparagine + pyruvate => 2-oxosuccinamate + L-alanine


name: NANP dephosphorylates Neu5Ac-9-P to Neu5Ac (Mus musculus)


name: ANO1 inhibitors bind ANO1 (Homo sapiens)


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Canis familiaris)


name: 2-oxoglutarate + N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + O2 => CO2 + H2O + isodomoate A + succinate


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Gallus gallus)


name: Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 (Homo sapiens)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Bos taurus)


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine


name: SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Gallus gallus)


name: AMP + diphosphate + L-glutamyl-tRNA(Gln) => ATP + L-glutamate + tRNA(Glu)


name: Acireductone is created (Saccharomyces cerevisiae)


name: glutarate(in) + prostaglandin E2(out) = glutarate(out) + prostaglandin E2(in)


name: A + H2O + uracil <=> AH2 + barbiturate + H(+)


name: Dissociation of the COP1-p53 complex (Danio rerio)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Rattus norvegicus)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Sus scrofa)


name: Expression of Lathosterol Oxidase (SC5D, SC5DL) (Homo sapiens)


name: DNA polymerase epsilon binds at the origin (Caenorhabditis elegans)


name: H2O + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) <=> acetate + alpha-D-glucosaminyl-[heparan sulfate](n)


name: H2O + N-(octanoyl)-sphing-4-enine-1-phosphate <=> N-octanoylsphing-4-enine + phosphate


name: SCUBE1, SCUBE3 oligomerize (Homo sapiens)


name: p-Y693-STAT4 dimerizes (Caenorhabditis elegans)


name: Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Xenopus tropicalis)


name: N-(2-hydroxy-hexanoyl)-sphinganine + UDP-alpha-D-galactose => H(+) + N-(2-hydroxyhexanoyl)-beta-D-galactosylsphinganine + UDP


name: an octanoate ester + H2O => an aliphatic alcohol + H(+) + octanoate


name: 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> cholesta-5,7-dien-3beta,24S-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NAD(+) + tartrate => 2-hydroxy-3-oxosuccinate + H(+) + NADH


name: AMP + diphosphate + hexadecanedioyl-CoA => ATP + CoA + hexadecanedioate


name: lipoteichoic acid immune receptor activity


name: Coumarin is 7-hydroxylated by CYP2A6 (Caenorhabditis elegans)


name: carminomycin + S-adenosyl-L-methionine => daunorubicin + H(+) + S-adenosyl-L-homocysteine


name: Association of procollagen type XXII (Caenorhabditis elegans)


name: a 1-acyl-sn-glycero-3-phosphocholine = a 2-acyl-sn-glycero-3-phosphocholine


name: D-isoleucine(out) + D-serine(in) => D-isoleucine(in) + D-serine(out)


name: a ganglioside GD1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1balpha  (d18:1(4E)) + CMP + H(+)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Dictyostelium discoideum)


name: H2O + norspermine + O2 => 3-aminopropanal + H2O2 + norspermidine


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Sus scrofa)


name: BLT receptors can bind LTB4 (Danio rerio)


name: histone H4K20 monomethyltransferase activity


name: benzaldehyde + FMN + H(+) + H2O + N-acetyl-S-hydroxy-L-cysteine => (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMNH2 + O2


name: Heparin binds PKR (Caenorhabditis elegans)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Caenorhabditis elegans)


name: H2O + N-(9Z-octadecenoyl)-ethanolamine phosphate = N-(9Z-octadecenoyl) ethanolamine + phosphate


name: dimethyl sulfoxide(in) <=> dimethyl sulfoxide(out)


name: H2O + N(omega)-methyl-L-arginine => L-citrulline + methylamine


name: 3'-phosphoadenylyl sulfate + tauro-alpha-muricholate = adenosine 3',5'-bisphosphate + H(+) + tauro-alpha-muricholate 7-sulfate


name: 3-phosphooxypyruvate + H(+) + NADH => (2R)-3-phosphoglycerate + NAD(+)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Xenopus tropicalis)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: ADP(in) + ATP(out) => ADP(out) + ATP(in)


name: Association of procollagen type V (Homo sapiens)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Caenorhabditis elegans)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Saccharomyces cerevisiae)


name: diphosphate + UMP => 5-phospho-alpha-D-ribose 1-diphosphate + uracil


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Sus scrofa)


name: acetone oxime + pyruvate => 2-(hydroxyimino)propanoate + acetone


name: 2 H(+)(in) + L-aspartate(in) = 2 H(+)(out) + L-aspartate(out)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Dictyostelium discoideum)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Mus musculus)


name: 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-heptadecanoyl-sn-glycero-3-phosphoserine + H(+)


name: glyoxylate + NH4(+) + urea => (S)-2-ureidoglycine + H2O


name: EEF1A1:GTP translocates from lysosomal membrane to cytosol (Homo sapiens)


name: NaS1 co-transports sulphate and a sodium ion (Sus scrofa)


name: Exchange of oxygen with sulfur in MoCo (Caenorhabditis elegans)


name: dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine <=> dTDP-alpha-D-forosamine + H(+) + S-adenosyl-L-homocysteine


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Bos taurus)


name: H(+) + N-acyl-3-oxosphinganine + NADH <=> an N-acylsphinganine + NAD(+)


name: PANK1/3 phosphorylate PanK (Rattus norvegicus)


name: 6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA


name: HMOX1 translocates from the cytosol to the nucleoplasm (Xenopus tropicalis)


name: a 2,3-diacyl-sn-glycerol + H2O => a 3-acyl-sn-glycerol + a fatty acid + H(+)


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Drosophila melanogaster)


name: USP11 deubiquitinates NFKBIA (Canis familiaris)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Homo sapiens)


name: ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate


name: (7S)-marmesin + O2 + reduced [NADPH--hemoprotein reductase] = acetone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + psoralen


name: ACAT1 tetramer acetylates IDH2 dimer (Danio rerio)


name: Phosphorylation of SHC1 (Xenopus tropicalis)


name: ALOXE3 isomerises 12R-HpETE to HXA3 (Danio rerio)


name: XDH oxidises 6MP to 6TU (Caenorhabditis elegans)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Bos taurus)


name: ROCK1,ROCK2 are activated (Xenopus tropicalis)


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Gallus gallus)


name: primary fluorescent dioxobilin-type chlorophyll catabolite methylesterase activity


name: H2O + primary fluorescent dioxobilin-type chlorophyll catabolite = H(+) + methanol + O13(4)-desmethyl pFDCC


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)


name: [(3R)-hydroxybutanoate](n) + H2O <=> (3R)-hydroxybutanoate trimer + [(3R)-hydroxybutanoate](n-3) + H(+)


name: a ganglioside Gal-GD1b (d18:1(4E)) + GDP-beta-L-fucose => a ganglioside Gal(Fuc)-GD1b (d18:1(4E)) + GDP + H(+)


name: (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP => indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose


name: Diacylgycerol activates Protein kinase C, alpha type (Dictyostelium discoideum)


name: ALOX5 oxidises EPA to 5-HEPE (Canis familiaris)


name: TFIIH binds GG-NER site to form a verification complex (Bos taurus)


name: EPHX1 hydrates BaP4,5O to BaP4,5-DHD (Sus scrofa)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Canis familiaris)


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Rattus norvegicus)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Rattus norvegicus)


name: H2O + L-leucine + O2 = 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Drosophila melanogaster)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP


name: CAMK4 autophosphorylates (Dictyostelium discoideum)


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Bos taurus)


name: AH2 + cyclohexane-1,3-dione => 3-hydroxycyclohexanone + A


name: ADP + an L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A


name: 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate => 5-phospho-alpha-D-ribose 1-diphosphate + ATP


name: DHFR dimer binds DHFR inhibitors (Bos taurus)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Rattus norvegicus)


name: MET bound PI3K generates PIP3 (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol <=> 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: kaempferol 3-O-beta-D-glucoside + malonyl-CoA => CoA + kaempferol 3-O-(6-O-malonyl-beta-D-glucoside)


name: H2O + O2 + S-(2E,6E)-farnesyl-L-cysteine => (2E,6E)-farnesal + H2O2 + L-cysteine


name: Oligomerization of Bcl10 (Gallus gallus)


name: double-stranded RNA adenosine deaminase activity


name: H(+) + malonyl-[ACP] + pentanoyl-CoA => 3-oxoheptanoyl-[ACP] + CO2 + CoA


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Rattus norvegicus)


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Bos taurus)


name: Dissociation of RAS:RAF complex (Homo sapiens)


name: Kinesin-3 is a dimer (Caenorhabditis elegans)