name: IL20 binds IL20RA:JAK1:IL20RB (Gallus gallus)


name: 16alpha,17beta-estriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase]


name: PSIP1 binds MLL1 and MEN1 (Drosophila melanogaster)


name: GLI2,3 are degraded by the proteasome (Mus musculus)


name: H2O + propanoyl-CoA <=> CoA + H(+) + propanoate


name: 2-oxoglutarate(out) + urate(in) = 2-oxoglutarate(in) + urate(out)


name: TDG glycosylase mediated recognition and binding of an uracil opposite to a guanine (Homo sapiens)


name: (9Z)-octadecenoate + (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-sn-glycerol) + H(+) => (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(2'-(9Z-octadecenoyl)-3'-sn-glycerol) + H2O


name: Collagen type IX degradation by MMP3,13 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate <=> aristolene + diphosphate


name: (R)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: Interleukin-12 binds Interleukin-12 receptor (Mus musculus)


name: ajmaline + S-adenosyl-L-methionine <=> 4-methylajmaline + H(+) + S-adenosyl-L-homocysteine


name: adenosine(1832) in 18S rRNA + S-adenosyl-L-methionine <=> H(+) + N(6)-methyladenosine(1832) in 18S rRNA + S-adenosyl-L-homocysteine


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphate + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphate


name: L-glutaminyl-[protein] + S-adenosyl-L-methionine => H(+) + N(5)-methyl-L-glutaminyl-[protein] + S-adenosyl-L-homocysteine


name: beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA (Mus musculus)


name: Defective RDH12 does not reduce atRAL to atROL (Homo sapiens)


name: ent-kaur-16-ene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = ent-kaur-16-en-19-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: carnosine(out) + H(+)(out) => carnosine(in) + H(+)(in)


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Rattus norvegicus)


name: C3 convertases spontaneously dissociate (Mus musculus)


name: CO2 + H(+) + succinate + validoxylamine B => 2-oxoglutarate + O2 + validoxylamine A


name: FadD26, FadD28 transfer adenylyl group to a LCFA (Mycobacterium tuberculosis)


name: 8 (S)-methylmalonyl-CoA + 24 H(+) + hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 16 NADPH = C40-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Canis familiaris)


name: LIAS synthesizes lipoyl-GCSH (Homo sapiens)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Danio rerio)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Mus musculus)


name: SRC-1 phosphorylates SHB (Rattus norvegicus)


name: Dephosphorylation of AKT by PP2A (Dictyostelium discoideum)


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Homo sapiens)


name: DIMBOA + UDP-alpha-D-glucose <=> DIMBOA beta-D-glucoside + H(+) + UDP


name: NF-kappa-B complex is transported from cytosol to nucleus (Rattus norvegicus)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Homo sapiens)


name: CHOL translocates from lysosome membrane to ER membrane (Caenorhabditis elegans)


name: genkwanin + O2 + reduced [NADPH--hemoprotein reductase] => H2O + oxidized [NADPH--hemoprotein reductase] + scutellarein 7-methyl ether


name: 9alpha-hydroxy-3-oxochol-4-en-22-oate + H2O + NAD(+) => 3-oxochol-4-en-22-oate + H(+) + NADH + O2


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Canis familiaris)


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)


name: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO2


name: SLC5A6 transports vitamins from extracellular region to cytosol (Rattus norvegicus)


name: (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + octanoyl-CoA => (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + CoA


name: IDUA hydrolyses Heparan sulfate chain(1) (Sus scrofa)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(32-hydroxydotriacontenoyl)-sphing-4-enine => a diacylglycerol + an N-(32-(9Z,12Z-octadecadienoyloxy)-dotriacontenoyl)-sphing-4-enine


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Bos taurus)


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Caenorhabditis elegans)


name: ATP + D-glucosamine => ADP + D-glucosamine 6-phosphate + H(+)


name: beta-alanyl-L-arginine + H2O => beta-alanine + L-arginine


name: POLA1 gene transcription is stimulated by E2F1 (Homo sapiens)


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Mus musculus)


name: chloride(out) + glycine betaine(out) + 2 Na(+)(out) = chloride(in) + glycine betaine(in) + 2 Na(+)(in)


name: Group 3 - Selective Cl- transport (Canis familiaris)


name: ADP + H(+) + L-kynurenine(in) + phosphate => ATP + H2O + L-kynurenine(out)


name: SUMOylation of NPM1 with SUMO2,3 (Sus scrofa)


name: 2'-deoxyadenosine(out) + H(+)(out) => 2'-deoxyadenosine(in) + H(+)(in)


name: 2 H2O + NH4(+) + 6 oxidized [2Fe-2S]-[ferredoxin] => 8 H(+) + nitrite + 6 reduced [2Fe-2S]-[ferredoxin]


name: H(+)(out) + L-histidine(out) <=> H(+)(in) + L-histidine(in)


name: Latent TGF-beta-1 binds integrins (Homo sapiens)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Danio rerio)


name: (2Z,6E)-farnesyl diphosphate => diphosphate + gamma-cadinene


name: CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate + H2O + NADP(+) => CMP-5'-(3-aminopropyl)phosphonate + NADPH + O2


name: cholesterol + NAD(+) = cholest-5-en-3-one + H(+) + NADH


name: 26-oxohexacosanoate + O2 + reduced [NADPH--hemoprotein reductase] => 2 H(+) + H2O + hexacosanedioate + oxidized [NADPH--hemoprotein reductase]


name: ATP + ethanolamine + L-glutamate <=> ADP + gamma-L-glutamylethanolamide + H(+) + phosphate


name: Exocytosis of tertiary granule lumen proteins (Dictyostelium discoideum)


name: O2 + reduced [NADPH--hemoprotein reductase] + taxusin => 2alpha-hydroxytaxusin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + L-cysteine <=> 2-oxo-3-sulfanylpropanoate + L-glutamate


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(34-hydroxytetratriacontenoyl)-sphing-4-enine = a diacylglycerol + an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontenoyl)-sphing-4-enine


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycerol


name: 4-methylsulfanyl-2-oxobutanoate + L-glutamine <=> 2-oxoglutaramate + L-methionine


name: 2,3-dioxo-L-gulonate => H2O + L-dehydroascorbate


name: IC-asc-C9-CoA + O2 => H2O2 + IC-asc-DeltaC9-CoA


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Sus scrofa)


name: H2O2 oxidizes Cys residues to form Cys-sulfenic acid (Homo sapiens)


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Caenorhabditis elegans)


name: RDH13 reduces atRAL to atROL (Sus scrofa)


name: 1-O-hexadecylglycerone 3-phosphate + H(+) + NADPH <=> 1-O-hexadecyl-sn-glycero-3-phosphate + NADP(+)


name: a medium-chain 3-oxoacyl-[ACP] + dihydroxyacetone phosphate => a 2-oxo-3-(phosphooxy)propyl medium-chain 3-oxoalkanoate + holo-[ACP]


name: ATP + streptidine => 6-O-adenylylstreptidine + diphosphate


name: ARFRP1 recruits ARL1 to the TGN (Rattus norvegicus)


name: L-glutamine + UDP-3-oxo-alpha-D-glucose <=> 2-oxoglutaramate + UDP-alpha-D-kanosamine


name: S-adenosyl-L-methionine + tyramine => H(+) + N-methyltyramine + S-adenosyl-L-homocysteine


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O => (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Bos taurus)


name: Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Schizosaccharomyces pombe)


name: 2 Na(+)(in) + nitrate(in) => 2 Na(+)(out) + nitrate(out)


name: WNT ligands traffic to the Golgi (Bos taurus)


name: Caspase-mediated cleavage of FADK 1 (Gallus gallus)


name: Binding of TFIIIB to SNAPc:Oct-1:Staf:Type 3 Promoter Complex (Gallus gallus)


name: Caspase-mediated cleavage of TJP1 (Sus scrofa)


name: HNF1B binds the IRX2 gene (Homo sapiens)


name: SKI complexes with the Smad complex, suppressing BMP2 signalling (Canis familiaris)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Caenorhabditis elegans)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Danio rerio)


name: H2O + N(omega)-hydroxy-L-arginine + NAD(+) => H(+) + L-arginine + NADH + O2


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + ADP + H(+) + phosphate => 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + ATP + H2O


name: DARPP-32 is dephosphorylated on Thr75 by PP2A (Bos taurus)


name: Translocation of ERBB4s80 to the nucleus (Xenopus tropicalis)


name: L-aspartate(in) + L-tryptophan(out) => L-aspartate(out) + L-tryptophan(in)


name: demethylphylloquinone + H(+) + NADPH = demethylphylloquinol + NADP(+)


name: B4GALT1 binds LALBA (Xenopus tropicalis)


name: desmethyldescarbamoylnovobiocin + S-adenosyl-L-methionine => descarbamoylnovobiocin + H(+) + S-adenosyl-L-homocysteine


name: C3PO hydrolyzes cleaved passenger strand (Sus scrofa)


name: CDP-choline + sphing-4-enine <=> CMP + H(+) + sphing-4-enine-phosphocholine


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP


name: ACHEIs bind ACHE (Drosophila melanogaster)


name: 2-oxoglutarate + 4-aminobutanoate => L-glutamate + succinate semialdehyde


name: (9S,13S,15Z)-12-oxophyto-10-15-dienoate + ATP + CoA = (10Z,15Z)-12-oxophytodienoyl-CoA + AMP + diphosphate


name: USP7 deubiquitinates monoubiquitinated PTEN (Gallus gallus)


name: IDO2 dioxygenates L-Trp to NFK (Rattus norvegicus)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Mus musculus)


name: butan-2-one + hydrogen cyanide => (2R)-2-hydroxy-2-methylbutanenitrile


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Drosophila melanogaster)


name: N-(dodecanoyl)-sphing-4-enine-1-phosphocholine => choline + N-dodecanoyl-sphing-4-enine-1,3-cyclic phosphate


name: chenodeoxycholate + NAD(+) <=> 7-oxolithocholate + H(+) + NADH


name: Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Bos taurus)


name: ADP + H(+) + L-arginine + phosphate <=> ATP + L-citrulline + NH4(+)


name: cysteamine + phosphate => cysteamine S-phosphate + H2O


name: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene <=> 1,2,3,5-tetrahydroxybenzene + 1,3,5-trihydroxybenzene


name: ecdysone + hexadecanoyl-CoA => CoA + ecdysone hexadecanoate


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Bos taurus)


name: Release of SEPT4 from mitochondria (Mus musculus)


name: PC is exchanged with PI by PITPNB (Drosophila melanogaster)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Rattus norvegicus)


name: Transport of antigen loaded MHC II molecules to surface (Canis familiaris)


name: a lactoside III(4)-a-Fuc-Lc4Cer + GDP-beta-L-fucose = a lactoside IV(2),III(4)-a-[Fuc]2-Lc4Cer + GDP + H(+)


name: G-protein beta-gamma subunits rebind the alpha-GDP subunit (Gallus gallus)


name: MDM2 translocates to the nucleus (Xenopus tropicalis)


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 2 (PAI-2) -> PAI-2:urokinase plasminogen activator (two-chain):uPAR (Bos taurus)


name: GBF1 stimulates nucleotide exchange on ARF4 (Mus musculus)


name: STAT1 and STAT3 dimers translocate to the nucleus (Xenopus tropicalis)


name: 2-oxoglutarate + 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + CO2 + succinate


name: 3-oxo-triacontanoyl-CoA + H(+) + NADPH <=> (3R)-hydroxytriacontanoyl-CoA + NADP(+)


name: a (3E)-enoyl-CoA + H2O => a 4-saturated-(3S)-3-hydroxyacyl-CoA


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Mus musculus)


name: Disassociation and translocation of STATs to the nucleus (Canis familiaris)


name: SLC43A1 (LAT3)-mediated uptake of large neutral amino acids (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeraniol + H(+) + NADPH + O2 = 16-hydroxy-(2E,6E,10E)-geranylgeraniol + H2O + NADP(+)


name: (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate => 2-oxoglutarate + 4-(phosphooxy)-L-threonine


name: L-arginine + pyruvate = 5-guanidino-2-oxopentanoate + L-alanine


name: Histone H2A is dubiquitinated by the PR-DUB complex (Bos taurus)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Bos taurus)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Rattus norvegicus)


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Homo sapiens)


name: RHOD translocates to the Golgi membrane (Bos taurus)


name: BRCA1:BARD1 heterodimer autoubiquitinates (Canis familiaris)


name: 3-oxo-(5Z)-dodecenoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxy-(5Z)-dodecenoyl-[ACP] + NADP(+)


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Caenorhabditis elegans)


name: Calmodulin activates Cam-PDE 1 (Bos taurus)


name: (+)-abscisic acid D-glucopyranosyl ester + H2O => 2-cis-(+)-abscisate + beta-D-glucose + H(+)


name: SMAD7:SMURF1 complex is exported to the cytosol (Homo sapiens)


name: (4Z,15Z)-bilirubin IXalpha + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) => biliverdin IXalpha + reduced coenzyme F420-(gamma-L-Glu)(n)


name: PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)


name: 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose <=> 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acylglycerol => a 1-acyl-sn-glycero-3-phosphoethanolamine + a 2,3-diacyl-sn-glycerol


name: (S)-benzodiazepinedione + dimethylallyl diphosphate = (2S,3R,11S)-aszonalenin + diphosphate


name: Type II receptor phosphorylates type I receptor (Canis familiaris)


name: botG HC transports botG LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: D-xylose + O2 = D-xylono-1,5-lactone + H2O2


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Canis familiaris)


name: CLPXP degrades mitochondrial matrix proteins (Rattus norvegicus)


name: DHNTP is dephosphorylated by PTPS to PTHP (Xenopus tropicalis)


name: 2 H2O + novapikromycin + 4 oxidized [2Fe-2S]-[ferredoxin] => 4 H(+) + narbomycin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: CO translocates from cytosol to extracellular region (Homo sapiens)


name: alpha-D-glucose + D-maltotetraose => D-maltopentaose + H2O


name: Co(I)-[glycine betaine-specific corrinoid protein] + glycine betaine + H(+) = methyl-Co(III)-[glycine betaine-specific corrinoid protein] + N,N-dimethylglycine


name: "glycine betaine--corrinoid protein Co-methyltransferase"


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)


name: L-arginine(in) + L-leucine(out) + Na(+)(out) = L-arginine(out) + L-leucine(in) + Na(+)(in)


name: Activation of highly calcium permeable nicotinic acetylcholine receptors (Danio rerio)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate => an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling (Bos taurus)


name: holo-[peptidyl-carrier protein] + L-arginyl-AMP => AMP + H(+) + L-arginyl-[peptidyl-carrier protein]


name: 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 <=> dichlorochromopyrrolate + H(+) + 2 H2O + NH4(+)


name: Proinsulin translocates from the endoplasmic reticulum to the Golgi (Bos taurus)


name: [thioredoxin]-dithiol + S-sulfanyl-L-cysteinyl-[protein] <=> [thioredoxin]-disulfide + H(+) + hydrogen sulfide + L-cysteinyl-[protein]


name: RPS6KA1-dependent phosphorylation of MITF-M (Drosophila melanogaster)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Homo sapiens)


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Mus musculus)


name: a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate <=> an alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Mus musculus)


name: HCMV Formation of Final Envelopment Complex (Homo sapiens)


name: Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex (Homo sapiens)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+) + NADPH = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + NADP(+)


name: SARS-CoV-2 3CLpro dimer binds to STING (Homo sapiens)


name: hexacosanoyl-CoA + O2 = (2E)-hexacosenoyl-CoA + H2O2


name: kaempferol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + quercetin


name: GBA3 hydrolyzes GlcCer (cytosol) (Sus scrofa)


name: "Transferring aldehyde or ketonic groups"


name: cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (25R)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) => a 1-acyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: 4-methylphenol + H2O + 2 oxidized [azurin] = 4-hydroxybenzyl alcohol + 2 H(+) + 2 reduced [azurin]


name: RBKS phosphorylates ribose to R5P (Drosophila melanogaster)


name: PIAS2-1 SUMOylates PARK7 with SUMO1 (Caenorhabditis elegans)


name: Type II receptor phosphorylates type I receptor (Sus scrofa)


name: 2 H2O + 2 L-dehydroascorbate => 2 L-ascorbate + O2


name: Interaction of DAP12 and TREM2 (Canis familiaris)


name: Co(II)-factor III + H(+) + S-adenosyl-L-methionine => Co(II)-factor IV + S-adenosyl-L-homocysteine


name: 17beta-hydroxy-5alpha-androstan-3-one + NAD(+) => 5alpha-androstan-3,17-dione + H(+) + NADH


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Rattus norvegicus)


name: PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Schizosaccharomyces pombe)


name: RAC3 translocates to the endoplasmic reticulum membrane (Mus musculus)


name: SUMOylation of Histone H4 with SUMO1 (Bos taurus)


name: RAS:GTP binds RAL GDS proteins (Bos taurus)


name: chloride(in) + L-threonine(in) + 2 Na(+)(in) => chloride(out) + L-threonine(out) + 2 Na(+)(out)


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Homo sapiens)


name: Phosphorylated MAPKs translocate into the nucleus (Danio rerio)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Homo sapiens)


name: 3-hydroxybutane-1,2,3-tricarboxylate => pyruvate + succinate


name: H(+)(in) + indole(in) = H(+)(out) + indole(out)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 oxidized [adrenodoxin] => (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: DELE1(143-515) binds EIF2AK1 (HRI) (Mus musculus)


name: ent-copalyl diphosphate = diphosphate + ent-isokaurene


name: a beta-D-xylosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = an N-acylsphing-4-enine + cholesteryl 3-beta-D-xyloside


name: 1,3-di-(9Z-octadecenoyl)-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate


name: Exocytosis of ficolin-rich granule membrane proteins (Sus scrofa)


name: SLCO2B1 has a narrow substrate specificity (Mus musculus)


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Rattus norvegicus)


name: (3R)-beta-leucine + H2O + NAD(+) = 4-methyl-3-oxopentanoate + H(+) + NADH + NH4(+)


name: ATP + L-leucine + tRNA(Leu) => AMP + diphosphate + L-leucyl-tRNA(Leu)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP


name: 2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine => 2-hydroxy-3-methoxy-17beta-estradiol + H(+) + S-adenosyl-L-homocysteine


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4 (Homo sapiens)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Mus musculus)


name: NADPH + 2 O2 => H(+) + NADP(+) + 2 superoxide


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + S-adenosyl-L-methionine => griseophenone D + H(+) + S-adenosyl-L-homocysteine


name: a jasmonyl-L-amino acid + H2O <=> a jasmonate + an L-alpha-amino acid


name: (9Z)-octadecenoyl-CoA + FAD + H(+) = (2E,9Z)-octadecadienoyl-CoA + FADH2


name: oligosaccharide reducing-end xylanase activity


name: RHOJ GEFs activate RHOJ (Rattus norvegicus)


name: 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Homo sapiens)


name: Caspase-mediated cleavage of FADK 1 (Mus musculus)


name: 2-oxoglutarate + O2 + octanoyl-CoA <=> 2-hydroxyoctanoyl-CoA + CO2 + succinate


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Bos taurus)


name: ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 (Rattus norvegicus)


name: citrate(in) + maleate(out) => citrate(out) + maleate(in)


name: Formation of the 43S pre-initiation complex (Drosophila melanogaster)


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Homo sapiens)


name: granulocyte colony-stimulating factor binding


name: 2-O-hexadecanoyl-alpha,alpha-trehalose + CoA => alpha,alpha-trehalose + hexadecanoyl-CoA


name: DAG and Ca+2 bind to PKC and tether it to membrane (Caenorhabditis elegans)


name: a 1-O-hexadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a 1-O-(1Z-hexadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: AKT-phosphorylated FOXO3 translocates to cytosol (Homo sapiens)


name: ABCA12 transports lipids from cytosol to extracellular region (Drosophila melanogaster)


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)


name: Dermatan sulfate can be further sulfated on position 2 of iduronate (Sus scrofa)


name: ATP + L-glutamate + spermine = ADP + gamma-L-glutamylspermine + H(+) + phosphate


name: PI3K synthesizes PIP3 downstream of ALK (Canis familiaris)


name: a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O <=> acetate + an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Homo sapiens)


name: H(+) + isopentadecanoyl-CoA + malonyl-CoA <=> 3-oxoisoheptadecanoyl-CoA + CO2 + CoA


name: acetate + ethanol + H(+) => ethyl acetate + H2O


name: CRHR1,CRHR2-1 binds CRH,UCN (Bos taurus)


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Drosophila melanogaster)


name: E-selectin binds E-selectin ligand (Xenopus tropicalis)


name: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD(+) = 6-oxocyclohex-1-ene-1-carbonyl-CoA + H(+) + NADH


name: polyamine transmembrane transporter activity


name: SFTPAs translocate from ER membrane to extracellular region (Gallus gallus)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Drosophila melanogaster)


name: I(1,4,5)P3 transports from the ER lumen to the cytosol (Homo sapiens)


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Danio rerio)


name: Transhomodimerization of Nectins (Caenorhabditis elegans)


name: beta-geranylfarnesene + diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: arsenite secondary active transmembrane transporter activity


name: (2R,3S)-piscidate + (E)-4-coumaroyl-CoA <=> cimicifugate K + CoA


name: CD22 binds itself to form homo-oligomers (Bos taurus)


name: GM2A binds and mobilizes ligands (Mus musculus)


name: 3-sulfanyl-1-pentanol + NH4(+) + pyruvate => 3-sulfanylpentan-1-ol-L-cysteine + H2O


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Schizosaccharomyces pombe)


name: Translocation of PDK1 to Plasma membrane (Caenorhabditis elegans)


name: all-trans-4-oxoretinoate + UDP-alpha-D-glucuronate => all-trans-4-oxoretinoate 1-O-(beta-D-glucuronate) + UDP


name: 12,18-didecarboxysiroheme + 2 AH2 + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 A + 2 acetate + Fe-coproporphyrin III + 2 H(+) + 2 L-methionine


name: MCM2-7 mediated fork unwinding (Homo sapiens)


name: Formation of ORC(1-5) complex (Bos taurus)


name: Hikeshi binds HSP70s:ATP (Saccharomyces cerevisiae)


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Saccharomyces cerevisiae)


name: SREBP1A,1C binds the SCD gene (Homo sapiens)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Mus musculus)


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Rattus norvegicus)


name: PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex (Bos taurus)


name: p-3Y-SHC1 dissociates from IGF1R (Sus scrofa)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Xenopus tropicalis)


name: D-sorbitol + NADP(+) => H(+) + L-xylo-3-hexulose + NADPH


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O


name: 2-O-sulfo-alpha,alpha-trehalose + hexadecanoyl-CoA = 2-O-sulfo-2'-O-hexadecanoyl-alpha,alpha-trehalose + CoA


name: a 3beta-hydroxysteroid + a triacylglycerol => a 3beta-hydroxysteroid ester + a diacylglycerol


name: AMP + an aromatic aldehyde + diphosphate + NADP(+) = an aromatic carboxylate + ATP + H(+) + NADPH


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Caenorhabditis elegans)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Xenopus tropicalis)


name: Cleavage of ethenoadenine by MPG glycosylase (Danio rerio)


name: rhamnetin + S-adenosyl-L-methionine => 3',4',5-trihydroxy-3,7-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: CSF1 dimer,IL34 dimer:p-Y561-CSF1R:GRB2:SOS1 dissociates yielding CSF1 dimer,IL34 dimer:p-Y561-CSF1R:SFK and GRB2:SOS1 (Homo sapiens)


name: Endocytosis of TGFBR3:ARRB complex (Caenorhabditis elegans)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Gallus gallus)


name: CoA + fumigaclavine A => acetyl-CoA + fumigaclavine B


name: Caspase mediated cleavage of HIP-55 (Drosophila melanogaster)


name: O2 + parthenolide + reduced [NADPH--hemoprotein reductase] = 3beta-hydroxyparthenolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Mus musculus)


name: Netrin-1 induced DCC clustering (Caenorhabditis elegans)


name: H(+) + hydrogen sulfide + O-phospho-L-seryl-tRNA(Cys) = L-cysteinyl-tRNA(Cys) + phosphate


name: 1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate


name: (+)-kolavelool + S-adenosyl-L-methionine <=> (+)-O-methylkolavelool + H(+) + S-adenosyl-L-homocysteine


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Drosophila melanogaster)


name: 3',5-dihydroxy-3,4',7-trimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Danio rerio)


name: 4-hydroxyeicosasphinganine 1-phosphate = 2-hydroxyoctadecanal + phosphoethanolamine


name: SLC16A10-mediated uptake of aromatic amino acids (Drosophila melanogaster)


name: Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Canis familiaris)


name: (9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + glycerol + H(+)


name: 3-oxopropanoate + H(+) + H2O2 + nitrite => H2O + O2 + propionate 3-nitronate


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Plasmodium falciparum)


name: Association of procollagen type VIII (Gallus gallus)


name: a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate => a ganglioside GD1a + CMP + H(+)


name: 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O


name: p-6Y-VEGFR2 binds SHC-transforming protein 2 (Xenopus tropicalis)


name: Tetrastatin binds integrin alphaVbeta3 (Drosophila melanogaster)


name: 11-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Melanospin is stimulated by light (Danio rerio)


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Sus scrofa)


name: Phenol can form a sulfate conjugate (Sus scrofa)


name: cyclohexane-1-carbonyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => cyclohex-1-ene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]


name: (-)-4'-methoxycyclopeptine + 2-oxoglutarate + O2 => (Z)-4'-methoxydehydrocyclopeptine + CO2 + H2O + succinate


name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Dictyostelium discoideum)


name: ATP binds G-protein beta associated TRiC/CCT (Plasmodium falciparum)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + H2O <=> ectocarpin D


name: dGMP + inosine = 2'-deoxyguanosine + IMP


name: 3-chloro-D-alanine + H2O => chloride + H(+) + NH4(+) + pyruvate


name: CYP17A1 17-hydroxylates P4 to 17aHPROG (Mus musculus)


name: (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + O2 <=> (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole-[protein] + H2O2


name: (1R,3R)-chrysanthemal + H2O + NAD(+) <=> (1R,3R)-chrysanthemate + 2 H(+) + NADH


name: 3 H(+) + 3 malonyl-CoA + N-methylanthraniloyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O


name: bile acid transmembrane transporter activity


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Sus scrofa)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Canis familiaris)


name: Activated MAPKs phosphorylate BRAF (Mus musculus)


name: 2-hydroxy-6-oxo-2,4-heptadienoate + H(+) => 3-methylcatechol + O2


name: Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Homo sapiens)


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT1] (Dictyostelium discoideum)


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Rattus norvegicus)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH => 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: acetyl-CoA + ADP + oxaloacetate + phosphate => ATP + citrate + CoA


name: 3-amino-4-hydroxybenzoate + H(+) + NADPH + O2 => 3-amino-2,4-dihydroxybenzoate + H2O + NADP(+)


name: carbon disulfide + H2O <=> carbonyl sulfide + H(+) + hydrogen sulfide


name: DCC interacts with DIP13alpha (Rattus norvegicus)


name: AMPK is dephosphorylated (Gallus gallus)


name: 5D-5-O-methyl-chiro-inositol + NADP(+) <=> 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH


name: 3,5,7,9,11-pentaoxododecanoyl-[ACP] <=> 6,8-dihydroxy-3-(2-oxopropyl)-isocoumarin + H2O + holo-[ACP]


name: an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = an anthocyanidin 3-O-sophoroside + 2 H(+) + UDP


name: p-T,Y MAPK dimers translocate to nucleus (Homo sapiens)


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Xenopus tropicalis)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + a cardiolipin => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: a ribonucleoside 5'-triphosphate + pyruvate = a ribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Sus scrofa)


name: CoA-dependent peptidyl-lysine N6-palmitoyltransferase activity


name: hexadecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] = CoA + H(+) + N(6)-hexadecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Sus scrofa)


name: 4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity


name: IRF2 binds the promoters of Interferon alpha and beta (Homo sapiens)


name: H2O + 2 NAD(+) + tetracenomycin C => 2 H(+) + 2 NADH + 2 O2 + tetracenomycin A2


name: (+)-pinoresinol + O2 + reduced [NADPH--hemoprotein reductase] => (+)-piperitol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-threonyl-[protein] + H(+) + UDP => L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Canis familiaris)


name: TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Gallus gallus)


name: IMPAD1 hydrolyses PAP to AMP (Danio rerio)


name: RUNX1, SPI1 (PU.1), GATA2, TAL1 (SCL), FLI1, and MYB bind the CEBPA promoter (Homo sapiens)


name: 3 O2 + obtusifoliol + 3 reduced [NADPH--hemoprotein reductase] = 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: octadecanoyl-CoA + sphinga-4E,14Z-dienine => CoA + H(+) + N-octadecanoyl-sphinga-4E,14Z-dienine


name: (2Z,6E)-farnesyl diphosphate + H2O <=> (6E)-nerolidol + diphosphate


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Rattus norvegicus)


name: (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + O2 + reduced [NADPH--hemoprotein reductase] <=> 5-dehydro-6-demethoxyfumagillol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: [(1->3)-alpha-D-glucosyl](n) + sucrose <=> [(1->3)-alpha-D-glucosyl](n+1) + D-fructose


name: atROL binds RBP1 to form RBP1:atROL (Bos taurus)


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Sus scrofa)


name: 3-deoxy-alpha-D-manno-oct-2-ulosonate + O2 <=> 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + H2O2


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Drosophila melanogaster)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Canis familiaris)


name: (indol-3-yl)acetyl-AMP + CoA <=> (indol-3-yl)acetyl-CoA + AMP + H(+)


name: carbon-oxygen lyase activity, acting on polysaccharides


name: O2 + quercetin <=> 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO


name: diphosphate + GDP-valienol => GTP + H(+) + valienol 1-phosphate


name: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine => D-glyceraldehyde 3-phosphate + H2O + L-tryptophan


name: 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + ATP + formate


name: MET phosphorylates CBL (Caenorhabditis elegans)


name: 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 => a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate


name: ATP + N-(D-erythrulosyl)-cadaverine => ADP + H(+) + N-(3-O-phospho-D-erythrulosyl)-cadaverine


name: (3R)-3-hydroxydecanoyl-CoA + NADP(+) <=> 3-oxodecanoyl-CoA + H(+) + NADPH


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Canis familiaris)


name: (E)-feruloyl-CoA + 2-oxoglutarate + O2 => (E)-6-hydroxyferuloyl-CoA + CO2 + succinate


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Dictyostelium discoideum)


name: Phosphorylation of cPLA2 by ERK-2 (Sus scrofa)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Caenorhabditis elegans)


name: acetyl-CoA + S-(2-succino)-L-cysteine = CoA + H(+) + N-acetyl-S-(2-succino)-L-cysteine


name: H(+)(in) + L-histidine(in) + L-ornithine(out) => H(+)(out) + L-histidine(out) + L-ornithine(in)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Drosophila melanogaster)


name: 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) <=> eupatolide + H2O


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Drosophila melanogaster)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Dictyostelium discoideum)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Mus musculus)


name: CBL ubiquitinates FRS2 and FGFR2 (Sus scrofa)


name: PDE4A,C,D hydrolyse cAMP (Xenopus tropicalis)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Gallus gallus)


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Homo sapiens)


name: F-actin capping protein binds to the barbed end of elongating F-actin (Homo sapiens)


name: I(1,4,5)P3 transports from the cytosol to the nucleus (Homo sapiens)


name: (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + NADPH <=> (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + NADP(+)


name: Association of mTERF with the termination sequence (Rattus norvegicus)


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Homo sapiens)


name: (5Z)-tetradecenoyl-CoA + (R)-carnitine => CoA + O-(5Z)-tetradecenoyl-(R)-carnitine


name: NFKB p105, TPL2 (COT) and ABIN2 form a stable complex (Xenopus tropicalis)


name: 2-oxoglutarate(in) + H(+)(in) = 2-oxoglutarate(out) + H(+)(out)


name: AMP + decanoyl-CoA + diphosphate => ATP + CoA + decanoate


name: Autocatalytic activation of MMP7 (Rattus norvegicus)


name: RPA binds to the Flap (Drosophila melanogaster)


name: (-)-alpha-acorenol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Sus scrofa)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Canis familiaris)


name: AKT phosphorylates FOXO1A (Drosophila melanogaster)


name: NEU3 hydrolyzes Neu5Ac from glycoconjugates (Danio rerio)


name: 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP => sn-glycerol 3-phosphate + UDP-alpha-D-galactose


name: Assembly of the destruction complex (Canis familiaris)


name: an adenosine in mRNA + CO2 + formaldehyde + succinate => 2-oxoglutarate + an N(1)-methyladenosine in mRNA + O2


name: CDC6 association with ORC(1-6) at replication origins (Dictyostelium discoideum)


name: androst-4-ene-3,17-dione + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = estrone + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Ubiquitinated RNF41 binds P-USP8 (Dictyostelium discoideum)


name: NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Sus scrofa)


name: L-tyrosyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + O-(N-acetyl-alpha-D-glucosaminyl)-L-tyrosyl-[protein] + UDP


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Xenopus tropicalis)


name: 13-dihydrocarminomycin + H(+) + NADPH + O2 <=> carminomycin + 2 H2O + NADP(+)


name: dibenzothiophene + 2 FMNH2 + 2 O2 = dibenzothiophene 5,5-dioxide + 2 FMN + 2 H(+) + 2 H2O


name: H2O + L-glutamate + NAD(+) => 2-oxoglutarate + H(+) + NADH + NH4(+)


name: (E,E)-sorbate + H(+) => (E)-1,3-pentadiene + CO2


name: Neuropeptide S receptor binds neuropeptide S (Rattus norvegicus)


name: ADK phosphorylates RBV (Saccharomyces cerevisiae)


name: ALD3A1 oxidises 4HPCP to CXPA (Mus musculus)


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Canis familiaris)


name: methylazoxymethanol + UDP-alpha-D-glucose = cycasin + H(+) + UDP


name: Calcium Binds Caldesmon (Drosophila melanogaster)


name: H(+) + N(1)-[(S)-3-amino-3-carboxypropyl]agmatine <=> CO2 + N(1)-(3-aminopropyl)agmatine


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Gallus gallus)


name: Formation of P-TEFb complex (Rattus norvegicus)


name: a ganglioside Ac-O-9-GD1a (d18:1(4E)) => a ganglioside Ac-O-8-GD1a (d18:1(4E))


name: Binding of cAMP to HCN channels (Sus scrofa)


name: H2O + N(alpha)-acetyl-L-methionine <=> acetate + L-methionine


name: PIAS1 SUMOylates SAFB with SUMO1 (Rattus norvegicus)


name: ASIC3 channel blockers bind ASIC3 trimer (Homo sapiens)


name: AH2 + androsta-1,4-diene-3,17-dione => A + androst-4-ene-3,17-dione


name: TDG excises 5-carboxylcytosine (Danio rerio)


name: RAC3 GDIs block activation of RAC3 (Danio rerio)


name: Formation of the CE:GMP intermediate complex (Gallus gallus)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Danio rerio)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Sus scrofa)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Bos taurus)


name: IL4I1:FAD oxidises L-Phe to kPPV (Xenopus tropicalis)


name: Activated FGFR1:p-FRS bind to PPTN11 (Gallus gallus)


name: 4-aminobutanoate + glyoxylate => glycine + succinate semialdehyde


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Rattus norvegicus)


name: 4-amino-3-all-trans-hexaprenylbenzoate + diphosphate => 4-aminobenzoate + all-trans-hexaprenyl diphosphate


name: L-alanine(out) + L-serine(in) => L-alanine(in) + L-serine(out)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Caenorhabditis elegans)


name: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA


name: antimonite secondary active transmembrane transporter activity


name: butanal + CoA + NADP(+) = butanoyl-CoA + H(+) + NADPH


name: Cleavage of Procaspase‑9 to caspase‑9 (Rattus norvegicus)


name: adenosine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methyladenosine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 2 hydroxylamine + 2 NAD(+) => 2 H(+) + hyponitrous acid + 2 NADH


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Bos taurus)


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Mus musculus)


name: Receptor FFAR2 binds carboxylates (Homo sapiens)


name: (1R,4R,5S)-(-)-guaia-6,10(14)-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: FOXA1 and GATA3 bind to CCND1 promoter (Bos taurus)


name: 3-keto-beta-D-galactose + beta-D-glucose => 3'-ketolactose + H2O


name: SUMOylation of HDAC2 with SUMO1 (Dictyostelium discoideum)


name: 16,17-didehydropregnenolone + UDP-alpha-D-glucose => 16,17-didehydropregnenolone 3-beta-D-glucoside + H(+) + UDP


name: ADA catalyzes the deamination of (deoxy)adenosine (Dictyostelium discoideum)


name: L-threonine + NAD(+) <=> (2S)-2-amino-3-oxobutanoate + H(+) + NADH


name: Dopa is oxidized to dopaquinone by TYR (Mus musculus)


name: G protein-coupled estrogen receptor 1 binds estrogen non-classically (Homo sapiens)


name: Recruitment of SYK to p-FCERI gamma subunit (Canis familiaris)


name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 (Rattus norvegicus)


name: C5AR2 binds anaphylatoxins and thier desArginated derivatives (Gallus gallus)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Drosophila melanogaster)


name: a quinone + H(+) + NADPH = a quinol + NADP(+)


name: Co-precorrin-6B + NAD(+) = Co-precorrin-6A + H(+) + NADH


name: GRB2-1:SOS1 binds p-Y-SHC (Gallus gallus)


name: (3S)-hydroxyhexadecanoyl-CoA => (2E)-hexadecenoyl-CoA + H2O


name: EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-CRKL:RAPGEF1 binds SHC1 (Homo sapiens)


name: AKAP8L binds MLL2 complex (Rattus norvegicus)


name: 3-dehydroquinate + H(+) + NADH => L-quinate + NAD(+)


name: 12-phosphooxy-(9E)-octadecenoate + H2O = 12-hydroxy-(9E)-octadecenoate + phosphate


name: diosgenin + UDP-alpha-D-glucose = diosgenin 3-O-beta-D-glucoside + H(+) + UDP


name: SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Dictyostelium discoideum)


name: CDO binds promyogenic cadherins (Mus musculus)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Homo sapiens)


name: 2 CoA + 2 H(+) + N(1),N(8)-bis(coumaroyl)-spermidine => 2 (E)-4-coumaroyl-CoA + spermidine


name: Ubiquitinated RNF41 binds P-USP8 (Homo sapiens)


name: AKT1 phosphorylates eNOS (Gallus gallus)


name: RAB1:GTP recruits GBF1 to the ERGIC (Drosophila melanogaster)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 3-methoxyphenol + H(+) + S-adenosyl-L-homocysteine => resorcinol + S-adenosyl-L-methionine


name: Defective APRT does not convert adenine to AMP (Homo sapiens)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + ATP = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+)


name: a 7-hydroxyisoflavone + S-adenosyl-L-methionine = a 7-methoxyisoflavone + H(+) + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + 5-dehydro-6-demethoxyfumagillol + O2 <=> 5-dehydro-6-demethoxy-6-hydroxyfumagillol + CO2 + succinate


name: 3',2'-cGAMP + diphosphate => pppA(2'-5')pG


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Mus musculus)


name: D-galactose + ganglioside GM2 (d18:1(4E)/18:0) => ganglioside GM1 (d18:1(4E)/18:0) + H2O


name: H2O + substance P => L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-6)


name: galactitol 1-phosphate(in) + L-histidyl-[protein] => galactitol(out) + N(pros)-phospho-L-histidyl-[protein]


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Mus musculus)


name: D-galactono-1,5-lactone + H2O = D-galactonate + H(+)


name: STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Rattus norvegicus)


name: LINC01139 facilitates PTK6 autophosphorylation (Homo sapiens)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Gallus gallus)


name: MAPK6 is degraded by the 26S proteasome (Sus scrofa)


name: an alcohol + glutathione disulfide + H2O => a hydroperoxide + 2 glutathione


name: 2-phenylethanol + acetyl-CoA = CoA + phenethyl acetate


name: mRNA9 is translated to protein 9b (Homo sapiens)


name: aspulvinone E + hnu <=> isoaspulvinone E


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)


name: H(+) + indole-3-propanoate + oxidized [electron-transfer flavoprotein] <=> (E)-3-(indol-3-yl)acrylate + reduced [electron-transfer flavoprotein]


name: NEU3 hydrolyzes Neu5Ac from glycoconjugates (Rattus norvegicus)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Bos taurus)


name: Inactivation of Myt1 kinase (Sus scrofa)


name: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + H(+)


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Homo sapiens)


name: NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Mus musculus)


name: p-S215 FOXO3 translocates to the nucleus (Homo sapiens)


name: D-serine(out) + Na(+)(out) => D-serine(in) + Na(+)(in)


name: D-phenylalanyl-tRNA(Phe) + H2O = D-phenylalanine + H(+) + tRNA(Phe)


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Sus scrofa)


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Bos taurus)


name: ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Dictyostelium discoideum)


name: Cho is acetylated to AcCho by CHAT (Sus scrofa)


name: (S)-2-benzylsuccinyl-CoA + succinate => (S)-2-benzylsuccinate + succinyl-CoA


name: NADP(+) + propan-2-ol => acetone + H(+) + NADPH


name: CYP3A4 can N-demethylate loperamide (Xenopus tropicalis)


name: a N-(2-hydroxyacyl)sphing-4-enine + UDP-alpha-D-galactose <=> a 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphing-4-enine + H(+) + UDP


name: Cleavage of Intronless Pre-mRNA at 3'-end (Homo sapiens)


name: DAG is acylated to TAG by DGAT1/2 (Homo sapiens)


name: 18S-resolvin E1 => (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: ADP(in) + dATP(out) <=> ADP(out) + dATP(in)


name: N-pyruvoyl-L-glutamate + salicylate => isochorismoyl-L-glutamate


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH => a long-chain fatty acyl-CoA + n CO2 + n CoA + H2O + 2n NADP(+)


name: (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+) => catechol + CO2 + NADH


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks (Gallus gallus)


name: NUDT16 hydrolyses IDP to IMP (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Homo sapiens)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Rattus norvegicus)


name: ING2 binds PI5P (Drosophila melanogaster)


name: SALL4 recruits NuRD to PTEN gene (Mus musculus)


name: 2-methylpentanoyl-CoA + AMP + diphosphate => 2-methylpentanoate + ATP + CoA


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol = a 1-acyl-sn-glycero-3-phosphoethanolamine + a triacyl-sn-glycerol


name: ATM phosphorylates WHSC1 (Gallus gallus)


name: choline(in) + H(+)(in) => choline(out) + H(+)(out)


name: methylmalonyl semialdehyde + NADH + H+ <=> beta-hydroxyisobutyrate + NAD+ (Dictyostelium discoideum)


name: histone H1R54 arginine deiminase activity


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: apo-[aequorin] + coelenterazine = apo-[aequorin]--coelenterazine


name: 3-dimethylallyl-4-hydroxymandelate + O2 = 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O


name: (3R)-3-[(carboxymethyl)amino]butanoate + 2 2-oxoglutarate + 2 O2 <=> (3R)-3-isocyanylbutanoate + 3 CO2 + 2 H2O + 2 succinate


name: A + H2O + uracil => AH2 + barbiturate + H(+)


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Canis familiaris)


name: TBC1D7 binds the TSC1-TSC2 complex (Sus scrofa)


name: an inositol-1-phosphophytoceramide + beta-D-mannose <=> a mannosylinositol-1-phosphophytoceramide + H2O


name: GP1b-IX-V binds filamin (Xenopus tropicalis)


name: B4GALTs transfer Gal to a branch of keratan (Rattus norvegicus)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Canis familiaris)


name: 6-demethylmitomycin B + S-adenosyl-L-methionine => mitomycin B + S-adenosyl-L-homocysteine


name: an inositol-1-phosphoceramide + H2O => 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Bos taurus)


name: ATP4A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Canis familiaris)


name: N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: Co-precorrin-6A + H(+) + NADH => Co-precorrin-6B + NAD(+)


name: RHOA GAPs stimulate RHOA GTPase activity (Mus musculus)


name: alpha-D-mannose 1-phosphate + GDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + GDP-alpha-D-mannose


name: (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA => (24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O


name: GNLY binds the bacterial cell surface in the phagosome (Danio rerio)


name: abieta-7,13-dien-18-ol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => abieta-7,13-dien-18-oate + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O <=> a 3'-end 3'-phospho-ribonucleotide-RNA + H(+)


name: a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]


name: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH


name: REV1 inserts dCMP opposite to AP sites in DNA (Canis familiaris)


name: Autophosphorylation of PDGF alpha/beta receptors (Bos taurus)


name: SLC25A11 exchanges 2-OG and MAL (Homo sapiens)


name: an alpha-L-fucoside + H2O <=> an alcohol + L-fucose


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Canis familiaris)


name: SPRY2 is serine phosphorylated in response to MAPK activation (Sus scrofa)


name: MECP2 binds CRH gene promoter (Homo sapiens)


name: Follicle-stimulating hormone receptor can bind FSH (Danio rerio)


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Sus scrofa)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Canis familiaris)


name: Phosphorylation of Syntaxin-4 (Rattus norvegicus)


name: asperaculane E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => asperaculane D + O2 + reduced [NADPH--hemoprotein reductase]


name: H(+) + malonyl-[ACP] <=> acetyl-[ACP] + CO2


name: Interaction of integrin alphaIIb beta3 with Fibrinogen (Bos taurus)


name: choline(out) + n Na(+)(out) <=> choline(in) + n Na(+)(in)


name: (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] <=> (13S,14R)-13-O-acetyl-1,8-dihydroxy-N-methylcanadine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (1S,2S,4R)-isodihydrocarveol + NAD(+) = (1S,4R)-isodihydrocarvone + H(+) + NADH


name: NICD1 PEST domain mutants in complex with RBPJ (CSL) bind MAML (Homo sapiens)


name: Crk binds to the active PDGF receptor (Xenopus tropicalis)


name: 2-haloacid dehalogenase (configuration-inverting) activity


name: SLC22A1 transports Cipro into hepatic cell (Canis familiaris)


name: (1H-indol-3-yl)-N-methylmethanamine + S-adenosyl-L-methionine <=> gramine + H(+) + S-adenosyl-L-homocysteine


name: Formation of PRC2-EZH2 complex (Mus musculus)


name: 16alpha-hydroxyestrone + UDP-alpha-D-glucuronate = 16alpha-hydroxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + NADP(+) => 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + H(+) + NADPH


name: H2O2 + N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone => N,N',N'',N'''-tetraacetylchitotetraose + O2


name: (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 <=> (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + (3R)-all-trans-3-hydroxyretinal


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Mus musculus)


name: gamma-tocopherol + S-adenosyl-L-methionine = (+)-alpha-tocopherol + H(+) + S-adenosyl-L-homocysteine


name: SLC22A12 exchanges extracellular urate for cytosolic LACT (Bos taurus)


name: 2 glutathione amide + NAD(+) => glutathione amide disulfide + H(+) + NADH


name: Cho is phosphorylated to PCho by CHK dimer (Rattus norvegicus)


name: CYP19A1 hydroxylates ANDST to E1 (Danio rerio)


name: 6-kestotriose + sucrose => 6,6-kestotetraose + beta-D-glucose


name: DSIF complex binds to RNA Pol II (hypophosphorylated) (Schizosaccharomyces pombe)


name: HTR1A binds HTR1A antagonists (Rattus norvegicus)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Saccharomyces cerevisiae)


name: glycyl-L-glutamine + H2O = glycine + L-glutamine


name: GM-CSF receptor alpha:GM-CSF binds Bc (Sus scrofa)


name: E and N are recruited to the M lattice (Homo sapiens)


name: GDP-valienol + validamine 7-phosphate = GDP + H(+) + validoxylamine A 7'-phosphate


name: 2,5-dioxopentanoate + H2O => 2-dehydro-3-deoxy-L-arabinonate


name: NADH + 2 O2 <=> H(+) + NAD(+) + 2 superoxide


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Dictyostelium discoideum)


name: (2S)-heptan-2-amine + H2O + NAD(+) = H(+) + heptan-2-one + NADH + NH4(+)


name: Dephosphorylation of AKT by PP2A (Schizosaccharomyces pombe)


name: ATP + L-seryl-[receptor-protein] = ADP + H(+) + O-phospho-L-seryl-[receptor-protein]


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Gallus gallus)


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Sus scrofa)


name: Dissociation of cytosolic HSF1:HSP90 complex (Gallus gallus)


name: Activated FGFR1 binds PLCG1 (Sus scrofa)


name: MKRN1 polyubiquitinates PTEN (Caenorhabditis elegans)


name: spermine dialdehyde => acrolein + N-(4-aminobutyl)-3-aminopropanal


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-GMP = glycolate + GMP + H(+)


name: Formation of ORC(2-5) complex (Rattus norvegicus)


name: ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Mus musculus)


name: an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + N-acetyl-D-galactosamine => an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Drosophila melanogaster)


name: acetyl-CoA + L-methionine => CoA + H(+) + N(alpha)-acetyl-L-methionine


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Homo sapiens)


name: 2 Na(+)(out) + taurochenodeoxycholate(out) => 2 Na(+)(in) + taurochenodeoxycholate(in)


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Saccharomyces cerevisiae)


name: Dissociation of insulin from insulin receptor (Gallus gallus)


name: HJURP:CENPA complex localizes to the centromere (Bos taurus)


name: SARS-CoV-2 3a tetramer binds to VPS39 within HOPS complex (Homo sapiens)


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Canis familiaris)


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Homo sapiens)


name: ADP + H(+) + N(5)-methyl-L-glutamine + phosphate => ATP + L-glutamate + methylamine


name: decanedioyl-CoA + O2 <=> (2E)-decenedioyl-CoA + H2O2


name: 3,4-dihydroxyphenylacetyl-CoA + H2O => 3,4-dihydroxyphenylacetate + CoA + H(+)


name: (E)-coniferaldehyde + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + H(+) + UDP


name: a neolactoside nLc4Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + CMP + H(+)


name: Dissociation of IRS-P from insulin receptor (Mus musculus)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Rattus norvegicus)


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Caenorhabditis elegans)


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Rattus norvegicus)


name: N-hydroxy-L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: CEMIP hydrolyses HA (Dictyostelium discoideum)


name: ABCG4 may mediate cholesterol efflux (Dictyostelium discoideum)


name: SLC35B4 mediates the transport of UDP-xylose into the Golgi lumen (Bos taurus)


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Danio rerio)


name: 2-acyl LPS is acylated to PS by LPSAT (Mus musculus)


name: MCM3 binds MCM5 (Saccharomyces cerevisiae)


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Danio rerio)


name: H2O + nicotinamide <=> NH4(+) + nicotinate


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Saccharomyces cerevisiae)


name: 4-O-(beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + H2O => 4-O-(beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Mus musculus)


name: PITPNM1,2,3 exchange PI for PA (Sus scrofa)


name: H2O + indole-3-acetaldehyde + NAD(+) = (indol-3-yl)acetate + 2 H(+) + NADH


name: Defective SLCO1B3 does not transport BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + ouabagenin => dihydroouabagenin + 2 Fe(III)-[cytochrome c]


name: FPGS-2 transforms THF to THFPG (Rattus norvegicus)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+) => a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate


name: Caspase 3-mediated cleavage of DFF45 (117) (Rattus norvegicus)


name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Homo sapiens)


name: RNA Pol II initiates transcription from damaged DNA template (Homo sapiens)


name: SARS-CoV-2 8:class I MHC binds BECN1 (Homo sapiens)


name: Phosphorylation of Syntaxin-4 (Canis familiaris)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: Ubiquitinated DVL is degraded by the proteasome (Homo sapiens)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O => n acetate + chitosan


name: Phosphorylation of PIP2 to PIP3 by PI3K (Rattus norvegicus)


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Dictyostelium discoideum)


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Dictyostelium discoideum)


name: Formation of AT-AC C complex (Gallus gallus)


name: lipopolysaccharide core heptosyltransferase activity


name: Caspase-mediated cleavage of Lamin A (Danio rerio)


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Plasmodium falciparum)


name: a 2'-deoxyribonucleoside 5'-phosphate + a 3'-end 2'-deoxyribonucleotide-DNA + H(+) => a 3'-end 2'-deoxyribonucleotidyl-deoxyribonucleotide-DNA + H2O


name: DEGS2 oxygenates dihydroceramide (Caenorhabditis elegans)


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Danio rerio)


name: 3beta-hydroxy-9beta-pimara-7,15-dien-19,6beta-olide + NADP(+) <=> H(+) + momilactone A + NADPH


name: H2O + NAD(+) + phosphonoacetaldehyde = 2 H(+) + NADH + phosphonoacetate


name: (2R)-3-phosphoglycerate + NAD(+) => 3-phosphooxypyruvate + H(+) + NADH


name: (2R,3S)-2,3-dimethylmalate <=> propanoate + pyruvate


name: AICAR + 10-Formyl-THF => FAICAR + THF (Caenorhabditis elegans)


name: all-trans-4,4'-diapo-zeta-carotene + FAD + H(+) = all-trans-4,4'-diaponeurosporene + FADH2


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O => a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Caenorhabditis elegans)


name: Keratin filaments bind cell-cell adhesion complexes (Rattus norvegicus)


name: nitronate monooxygenase (FMN-linked) activity


name: 3-carboxy-2-oxobutanoate + H(+) = 2-oxobutanoate + CO2


name: poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Dictyostelium discoideum)


name: 3,4-dihydroxybenzoate + CO2 => 4,5-dihydroxyphthalate + H(+)


name: Activated FGFR1 phosphorylates PLCG1 (Gallus gallus)


name: Dopachrome is transformed to DHICA by DCT (Rattus norvegicus)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: 7-oxocholesterol + H(+) + NADPH = 7beta-hydroxycholesterol + NADP(+)


name: 2-methylbutan-1-ol + butanoyl-CoA <=> 2-methylbutyl butanoate + CoA


name: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate => D-glyceraldehyde 3-phosphate + indole


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Gallus gallus)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Bos taurus)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Bos taurus)


name: [thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA


name: 2-hydroxymethyl-3-pentylphenol + O2 + reduced [NADPH--hemoprotein reductase] <=> (8S)-annullatin E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate (Gallus gallus)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:PTPN11:IL10RB:p-TYK2 binds STAT3 (Mus musculus)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Saccharomyces cerevisiae)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Bos taurus)


name: chloride(out) + glycine(out) + 2 Na(+)(out) => chloride(in) + glycine(in) + 2 Na(+)(in)


name: 3'-phosphoadenylyl sulfate + 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] => 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Drosophila melanogaster)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: 9beta-pimara-7,15-dien-19-ol + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Sus scrofa)


name: H(+) + hypotaurine + NADPH + O2 <=> H2O + NADP(+) + taurine


name: pseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylpseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-homocysteine


name: n a quinone + n H(+) + n hydrogen sulfide <=> n a quinol + n sulfur


name: (2S)-2-acetolactate + H(+) => (R)-acetoin + CO2


name: glycodeoxycholate(out) + 2 Na(+)(out) <=> glycodeoxycholate(in) + 2 Na(+)(in)


name: 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine = 4-O-([2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine-phospho-ribonucleoside in mRNA + H2O = (N(7)-methyl 5'-triphospho-guanosine)-guanosine + a 5'-end phospho-ribonucleoside in mRNA + H(+)


name: 2-[(E)-caffeoyl]-D-threo-isocitrate(3-) + CoA => (E)-caffeoyl-CoA + D-threo-isocitrate


name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol (Mus musculus)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Rattus norvegicus)


name: trans-4-hydroxy-L-proline + ubiquinone-10 <=> (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + H(+) + ubiquinol-10


name: (2E,6E)-farnesyl diphosphate <=> (1S,5S,6R)-alpha-bergamotene + diphosphate


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Drosophila melanogaster)


name: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O => D-ribose 2,5-bisphosphate + H(+)


name: ADP + glycocholate(out) + H(+) + phosphate => ATP + glycocholate(in) + H2O


name: MAP kinase p38 phosphorylates KSRP (Homo sapiens)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Xenopus tropicalis)


name: 4-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate => 4-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: 2-phenylacetate + ATP + CoA = AMP + diphosphate + phenylacetyl-CoA


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Xenopus tropicalis)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Caenorhabditis elegans)


name: DCXR tetramer reduces L-xylulose to xylitol (Canis familiaris)


name: acetyl-CoA + horhammericine = 19-O-acetylhorhammericine + CoA


name: Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3. (Gallus gallus)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Caenorhabditis elegans)


name: luteolin + S-adenosyl-L-methionine => H(+) + luteolin 7-methyl ether + S-adenosyl-L-homocysteine


name: beta-D-fructose 1-phosphate <=> D-glyceraldehyde + dihydroxyacetone phosphate


name: 3-oxochol-4-en-24-oyl-CoA + A => (22E)-3-oxochola-4,22-dien-24-oyl-CoA + AH2


name: TXLNA (IL14) binds syntaxin4 (Mus musculus)


name: RHOD translocates to the Golgi membrane (Schizosaccharomyces pombe)


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Gallus gallus)


name: Phosphorylation of LIMK-1 by PAK (Gallus gallus)


name: PAN2-PAN3 complex partially deadenylates mRNA (Sus scrofa)


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + veratrole = 3-methoxyphenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: (2E)-hexadecenoyl-CoA + H(+) + NADPH <=> hexadecanoyl-CoA + NADP(+)


name: H2O + N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine = 1-hexadecanoyl-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: ATP + H2O + L-methionine(out) => ADP + H(+) + L-methionine(in) + phosphate


name: H2O + N,1-diacyl-sn-glycero-3-phosphoethanolamine <=> a 1-acyl-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)


name: H(+)(out) + putrescine(out) => H(+)(in) + putrescine(in)


name: N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP


name: Cleavage of thymine by TDG glycosylase (Canis familiaris)


name: RNA polymerase II core promoter sequence-specific DNA binding


name: B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD (Mus musculus)


name: 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)


name: ABCC4 accumulation of dense granule contents (Rattus norvegicus)


name: Formation of ORC(1-6) complex (Rattus norvegicus)


name: AGK:Mg2+ phosphorylates MAG, DAG (Caenorhabditis elegans)


name: ARL3 hydrolyzes GTP (Caenorhabditis elegans)


name: Active LTK receptor binds SHC1 (Rattus norvegicus)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Rattus norvegicus)


name: Phosphorylation and activation of VAV1 (Canis familiaris)


name: RNF41 ubiquitinates activated ERBB3 (Drosophila melanogaster)


name: Interaction of beta-2-microglobulin (B2M) chain with  class I HC (Mus musculus)


name: 2 H(+) + N-succinyl-L-glutamate + NADH => H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+)


name: SGK phosphorylates CREB1 (Canis familiaris)


name: 4-phosphooxy-L-aspartyl-tRNA(Asn) + ADP + H(+) => ATP + L-aspartyl-tRNA(Asn)


name: FDPS dimer transfers IPPP to GPP (Homo sapiens)


name: Hemes bind to BACH1:MAFK (Gallus gallus)


name: 3-amino-2,3-dideoxy-scyllo-inosose + L-glutamine => 2-deoxystreptamine + 2-oxoglutaramate


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Gallus gallus)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Homo sapiens)


name: DENND1s exchange GTP for GDP on RAB35 (Canis familiaris)


name: NADP(+) + octanoyl-CoA => (2E)-octenoyl-CoA + H(+) + NADPH


name: nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Rattus norvegicus)


name: H2O + L-asparagine + O2 <=> 2-oxosuccinamate + H2O2 + NH4(+)


name: C30 botryococcene + S-adenosyl-L-methionine <=> 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylation of CTLA-4 (Mus musculus)


name: (S)-3-amino-3-phenylpropanoate + 2-oxoglutarate => 3-oxo-3-phenylpropanoate + L-glutamate


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Dictyostelium discoideum)


name: kainate receptor binds glutamate (Caenorhabditis elegans)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Homo sapiens)


name: SIRPA binds SFTPA oligomer, SFTPD oligomer (Rattus norvegicus)


name: arsenate(in) + H(+)(in) <=> arsenate(out) + H(+)(out)


name: ICOS binds ICOSL/B7-H2 (Rattus norvegicus)


name: atRAL is reduced to atROL (Drosophila melanogaster)


name: (1R,6S)-isopiperitenol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (4R)-limonene + O2 + reduced [NADPH--hemoprotein reductase]


name: L-isoleucine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (1E,2S)-2-methylbutanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: USP5 cleaves polyubiquitin (Homo sapiens)


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Rattus norvegicus)


name: GIP receptor binds gastric inhibitory peptide (Rattus norvegicus)


name: MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Gallus gallus)


name: PRKCZ recruits RAS in response to estrogen stimulation (Gallus gallus)


name: 1-phenylethanol + NAD(+) <=> acetophenone + H(+) + NADH


name: MITF-M dimer binds the LIG1 gene (Homo sapiens)


name: H2O + N-sulfo-D-glucosamine = D-glucosamine + sulfate


name: Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Sus scrofa)


name: α1-agonists bind ADRA1A,B,D (Xenopus tropicalis)


name: Thrombin-activated PARs activate Gq (Sus scrofa)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[12] (Drosophila melanogaster)


name: GDP-beta-L-fucose(out) + GMP(in) => GDP-beta-L-fucose(in) + GMP(out)


name: Expression of GDNF in metanephric mesenchyme (Homo sapiens)


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Rattus norvegicus)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Homo sapiens)


name: ALK binds ligand pleiotrophin (PTN) (Mus musculus)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Drosophila melanogaster)


name: KRAS4B is phosphorylated on serine 181 (Bos taurus)


name: PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: TGFBR3(1-783) binds to TGFB1,TGFB2 (Sus scrofa)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Dictyostelium discoideum)


name: 2-oxoglutarate + ATP + hydrogencarbonate = (S)-oxalosuccinate + ADP + H(+) + phosphate


name: PDPK1 phosphorylates SGK1 (Canis familiaris)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Sus scrofa)


name: LRRC16A binds F-actin capping protein (Rattus norvegicus)


name: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O = 5-deoxy-D-glucuronate + H(+)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Sus scrofa)


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Saccharomyces cerevisiae)


name: MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) (Danio rerio)


name: (2E)-dodecenoyl-CoA + H(+) + NADH => dodecanoyl-CoA + NAD(+)


name: Displacement of C2a/Bb by CR1 (Gallus gallus)


name: H(+) + NADPH + O2 + protoviolaceinate => H2O + NADP(+) + violaceinate


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Bos taurus)


name: ATP + D-maltose(out) + H2O = ADP + D-maltose(in) + H(+) + phosphate


name: 26-hydroxylanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => lanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol = 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: (+)-sesamin dicatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) => (+)-sesamin monocatechol + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n)


name: a guanosine in mRNA + S-adenosyl-L-methionine = an N(7)-methylguanosine in mRNA + S-adenosyl-L-homocysteine


name: Release Of ADP From Myosin (Homo sapiens)


name: angiotensin-(1-7) + H2O <=> angiotensin-(1-5) + L-histidyl-L-proline


name: D-tryptophan + O2 <=> N-formyl-D-kynurenine


name: 4'-methoxyviridicatin + H(+) + methyl isocyanate => (-)-4'-methoxycyclopenine


name: CHEK2 phosphorylates TP53 (Mus musculus)


name: The Ligand:GPCR:Gz complex dissociates (Xenopus tropicalis)


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Homo sapiens)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Rattus norvegicus)


name: ADP + H(+) + phosphate + urate(out) => ATP + H2O + urate(in)


name: (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP


name: ATP + L-seryl-[low-density-lipoprotein receptor] => ADP + H(+) + O-phospho-L-seryl-[low-density-lipoprotein receptor]


name: a carboxylate + ATP + CoA => AMP + an acyl-CoA + diphosphate


name: Pol II elongation complex moves on the template as transcript elongates (Drosophila melanogaster)


name: Activation of proMMP11 by FURIN (Xenopus tropicalis)


name: O2 + reduced [NADPH--hemoprotein reductase] + solavetivol => H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + solavetivone


name: a ganglioside GD3 + acetyl-CoA <=> a ganglioside Ac-O-7-GD3 + CoA


name: Excision of FapyG by OGG1 glycosylase (Bos taurus)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Xenopus tropicalis)


name: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methyladenosine(1067) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Caspase mediated cleavage of C-IAP1 (Drosophila melanogaster)


name: (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(2'-(9Z-octadecenoyl)-3'-sn-glycerol) + H2O => (9Z)-octadecenoate + (R,R)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-sn-glycerol) + H(+)


name: (8Z,11Z)-eicosadienoyl-CoA + A + 2 H2O => (11Z)-eicosenoyl-CoA + AH2 + O2


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Homo sapiens)


name: 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-glucuronate <=> 3-O-[beta-D-GlcA-(1->3)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP


name: IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Sus scrofa)


name: 4-methyl-5-nitrocatechol + NADH + O2 => 2-hydroxy-5-methylquinone + H(+) + H2O + NAD(+) + nitrite


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Dictyostelium discoideum)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Sus scrofa)


name: JMJD6 demethylates MeR4-HIST1H4 (Mus musculus)


name: Nucleophillic attack by 3'-hydroxyl oxygen of nascent HIV-1 transcript on the Alpha phosphate of NTP (Homo sapiens)


name: Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex (Rattus norvegicus)


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SPHK1 phosphorylates sphingosine in response to E2 stimulation (Schizosaccharomyces pombe)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Mus musculus)


name: a 1-acyl-sn-glycero-3-phosphocholine(out) + Na(+)(out) => a 1-acyl-sn-glycero-3-phosphocholine(in) + Na(+)(in)


name: PEA15 binds MAPK monomers and dimers (Canis familiaris)


name: dinucleotide insertion or deletion binding


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H(+) + NADH => 4-pyridoxate + NAD(+)


name: OPN (osteopontin) degradation by MMP3, MMP7 (Gallus gallus)


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene + A <=> 1'-hydroxy-demethylspheroidene + AH2


name: (2E,6E,10E)-geranylgeranyl diphosphate = ent-copalyl diphosphate


name: 2 (3R)-3-isocyanylbutanoyl-[ACP] + ATP + L-lysine + 2 NADPH <=> (2S)-2,6-bis[(3R)-3-isocyanobutanamido]hexan-1-ol + AMP + diphosphate + 2 holo-[ACP] + 2 NADP(+)


name: 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H2O = chloride + 2 H(+) + maleylacetate


name: Phosphorylated SHC recruits GRB2:SOS1 (Mus musculus)


name: (3R)-hydroxybutanoate tetramer + H2O => (3R)-hydroxybutanoate trimer + (R)-3-hydroxybutanoate + H(+)


name: 2 a ubiquinol + 4 H(+)(in) + O2(in) <=> 2 a ubiquinone + 4 H(+)(out) + 2 H2O(in)


name: 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin <=> 2-oxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: SYK binds the activated BCR (Bos taurus)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) <=> a 1-acyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: (5R)-5-phosphooxy-L-lysine + H2O = (S)-2-amino-6-oxohexanoate + NH4(+) + phosphate


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Homo sapiens)


name: Phosphorylation of SHC1 by p-5Y-EGFRvIII (Homo sapiens)


name: SLC52A1,2,3 transport RIB from extracellular region to cytosol (Canis familiaris)


name: MECP2 binds NOTCH1 gene promoter (Homo sapiens)


name: AURKA phosphorylates PLK1 (Gallus gallus)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Danio rerio)


name: Formation of NR-MED1 Coactivator Complex (Mus musculus)


name: H2O + NAD(+) + quinoline-2,8-diol => H(+) + NADH + O2 + quinolin-2-ol


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-nonadecanoyl-sn-glycero-3-phosphocholine <=> 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Gallus gallus)


name: FGF2:TGFBR3 binding to GIPC1 (Sus scrofa)


name: Co(I)-[methanol-specific corrinoid protein] + H(+) + methanol = H2O + methyl-Co(III)-[methanol-specific corrinoid protein]


name: (2E,6E)-farnesyl diphosphate = beta-bisabolene + diphosphate


name: 2-succinylbenzoyl-CoA + H(+) <=> 1,4-dihydroxy-2-naphthoyl-CoA + H2O


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Homo sapiens)


name: a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA


name: 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 => H2O + NADP(+) + pentalenolactone D


name: CK2 phosphorylates condensin I subunits (Rattus norvegicus)


name: dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Homo sapiens)


name: (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + tetradecanoyl-[ACP] <=> ((9Z)-hexadecenoyl-tetradecanoyl)-(Kdo)2-lipid A + holo-[ACP]


name: 2 CO2 + NH4(+) => cyanate + 3 H(+) + hydrogencarbonate


name: B4GALTs transfer Gal to a branch of keratan (Drosophila melanogaster)


name: N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose <=> beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + H(+) + UDP


name: Protein N forms hendecamers (Homo sapiens)


name: AGK:Mg2+ phosphorylates MAG, DAG (Xenopus tropicalis)


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Sus scrofa)


name: L-tryptophan + O2 = CO2 + H2O + indole-3-acetamide


name: NH4(+) + uridine(6666) in apoB mRNA => cytidine(6666) in apoB mRNA + H(+) + H2O


name: PIAS4 SUMOylates VHL with SUMO1 (Gallus gallus)


name: carminomycin + S-adenosyl-L-methionine <=> daunorubicin + H(+) + S-adenosyl-L-homocysteine


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Rattus norvegicus)


name: H(+) + NADPH + progesterone => 3beta-hydroxypregn-4-ene-20-one + NADP(+)


name: 3-deoxyfructose + NADP(+) <=> 3-deoxyglucosone + H(+) + NADPH


name: ROCK1,ROCK2 are activated (Drosophila melanogaster)


name: 24-methylenecycloartanol 4alpha-methyl oxidase activity


name: 5-methylcytidine(72) in tRNA(Thr) + H(+) + S-adenosyl-L-homocysteine => cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine


name: MAP2K1 binds MAPK3 (Drosophila melanogaster)


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2 => (1-deoxy-D-fructos-1-yl)amine + an aldehyde + H2O2


name: NUDT2 hydrolyses GP4G to GTP, GMP (Canis familiaris)


name: PS transports from the ER membrane to the IM membrane (Homo sapiens)


name: Digestion of branched starch (amylopectin) by extracellular amylase (Sus scrofa)


name: 2 H(+) + N,N-dimethylglycine + 2 S-adenosyl-L-homocysteine => glycine + 2 S-adenosyl-L-methionine


name: ATP + Ca(2+)(in) + H2O <=> ADP + Ca(2+)(out) + H(+) + phosphate


name: a fatty acid + ATP + CoA = a fatty acyl-CoA + AMP + diphosphate


name: Calmodulin activates Cam-PDE 1 (Rattus norvegicus)


name: a 3'-end 2'-deoxyribonucleotide-DNA + phosphate => a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H2O


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Dictyostelium discoideum)


name: PTPN6 dephosphorylates JAK3 (Rattus norvegicus)


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Xenopus tropicalis)


name: D-alanine(in) + H(+)(in) = D-alanine(out) + H(+)(out)


name: MET dimers autophosphorylate (Sus scrofa)


name: H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2


name: 4-O-deacetylvindoline + acetyl-CoA => CoA + vindoline


name: (3R)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) => 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + NADH


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: 3 H2O2 + protoporphyrin IX => 3 O2 + protoporphyrinogen IX


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Homo sapiens)


name: 2-oxoglutarate + 3-methylundecanoyl-CoA + O2 => 2-hydroxy-3-methylundecanoyl-CoA + CO2 + succinate


name: an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O = 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Mus musculus)


name: 2 H(+) + NADPH + 2 O2 + protoviolaceinate = CO2 + 2 H2O + NADP(+) + violacein


name: glucose + ATP => glucose 6-phosphate + ADP (Gallus gallus)


name: carnosine + S-adenosyl-L-methionine <=> anserine + H(+) + S-adenosyl-L-homocysteine


name: ATP + xylitol <=> ADP + H(+) + xylitol 5-phosphate


name: 3,6-dichlorocatechol + O2 => (2E,4E)-2,5-dichloromuconate + H(+)


name: Formation of active mTORC1 complex (Bos taurus)


name: KRAS4B is phosphorylated on serine 181 (Mus musculus)


name: SLC25A10 mediates exchange of malate and phosphate (Danio rerio)


name: 2 L-arginine + 4 O2 + 3 reduced [flavodoxin] <=> 5 H(+) + 4 H2O + 2 L-citrulline + 2 nitric oxide + 3 oxidized [flavodoxin]


name: Hh C-terminal fragments are degraded by the proteasome (Sus scrofa)


name: Receptor FFAR2 binds carboxylates (Canis familiaris)


name: a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O => a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: KAT5 acetylates ATM at shortened telomeres (Dictyostelium discoideum)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphoethanolamine + acetate + H(+)


name: 1-acyl LPE is acylated to PE by LPEAT (Dictyostelium discoideum)


name: an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] <=> 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]


name: ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Mus musculus)


name: calcidiol + UDP-alpha-D-glucuronate => calcidiol 25-O-(beta-D-glucuronide) + H(+) + UDP


name: 2-dehydropantoate => 3-methyl-2-oxobutanoate + formaldehyde


name: NAD(+) + prostaglandin E1 => 15-oxoprostaglandin E1 + H(+) + NADH


name: Serine phosphorylation of STATs (Bos taurus)


name: SHP1 and SHP2 bind the common beta chain (Mus musculus)


name: MYC/MYCN bind the ALK gene (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho]-glycerol + CoA


name: MDH2 dimer dehydrogenates MAL (Saccharomyces cerevisiae)


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Canis familiaris)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Mus musculus)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Mus musculus)


name: [thioredoxin]-disulfide + H2O + L-methionine => [thioredoxin]-dithiol + L-methionine (S)-S-oxide


name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa (Gallus gallus)


name: p-Y705, S727 STAT3 dimer binds HIF1A gene (Homo sapiens)


name: L-alanine(in) + Na(+)(in) <=> L-alanine(out) + Na(+)(out)


name: PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Drosophila melanogaster)


name: Squalene is oxidized to its epoxide (Homo sapiens)


name: H2O + N-formimidoyl-L-glutamate => formamide + L-glutamate


name: ATP + L-threonyl-[tau protein] <=> ADP + H(+) + O-phospho-L-threonyl-[tau protein]


name: STAT5 is recruited by JAK2 (Rattus norvegicus)


name: estrone + PAPS => estrone 3-sulfate + PAP (Sus scrofa)


name: 15-methylhexadecasphinganine + ATP => 15-methylhexadecasphinganine 1-phosphate + ADP + H(+)


name: Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Homo sapiens)


name: diphosphate + sabinene => (2E)-geranyl diphosphate


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + heptadecanoyl-CoA + O2 <=> (9Z)-heptadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Drosophila melanogaster)


name: beta-alanyl-dopamine + H2O => beta-alanine + dopamine


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Bos taurus)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Canis familiaris)


name: sulfur transfer to carrier protein (Mycobacterium tuberculosis)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Sus scrofa)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-4-phosphate) + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: H2O + NADP(+) + nitrosobenzene => H(+) + NADPH + nitrobenzene


name: SENP1,2,5 proteolytically process SUMO2 (Xenopus tropicalis)


name: 2-methylbutanamine + H2O + NADP(+) <=> 2-methylbutanal + H(+) + NADPH + NH4(+)


name: Hydrolysis of Ran:GTP to Ran:GDP (Homo sapiens)


name: LIG1 bound to POLB ligates SSB (Rattus norvegicus)


name: Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Homo sapiens)


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Sus scrofa)


name: p-PKR dimer phosphorylates MAPT (Homo sapiens)


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Saccharomyces cerevisiae)


name: LTA4 is hydolysed to LTB4 by LTA4H (Homo sapiens)


name: POLD,POLE-mediated DNA strand displacement synthesis (Sus scrofa)


name: Dissociation of paradoxically activated RAS:BRAF complexes (Homo sapiens)


name: ADP + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(out) + H(+) + phosphate => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(in) + ATP + H2O


name: NOTCH3 gene transcription (Homo sapiens)


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Bos taurus)


name: kaempferide + S-adenosyl-L-methionine => 7,4'-O-dimethylkaempferol + H(+) + S-adenosyl-L-homocysteine


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Danio rerio)


name: 6alpha-hydroxy-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase] = 28-nortyphasterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: dGDP + H(+) + phosphoenolpyruvate => dGTP + pyruvate


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Xenopus tropicalis)


name: a 2-oxocarboxylate + L-asparagine = 2-oxosuccinamate + an L-alpha-amino acid


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Gallus gallus)


name: Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Rattus norvegicus)


name: cis-4-hydroxy-L-proline + NAD(+) = 4-oxo-L-proline + H(+) + NADH


name: TBK1, IKBKE phosphorylate RIPK1 at T189 (Homo sapiens)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Canis familiaris)


name: a triacylglycerol + CoA => a 1,3-diacylglycerol + an acyl-CoA


name: Recruitment of HDAC1 by p107 (RBL1) (Caenorhabditis elegans)


name: a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + NADH + O2 <=> a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + H2O + NAD(+)


name: Recruitment of CstF to the CPSF Bound Pre-mRNA (Drosophila melanogaster)


name: GLYAT-like proteins transfer glycine to 2,5-DHB-CoA to form gentisuric acid (Caenorhabditis elegans)


name: L-arginine(in) + L-glutamine(out) + Na(+)(out) => L-arginine(out) + L-glutamine(in) + Na(+)(in)


name: IFNAR1:TYK2 binds TYK2 inhibitors (Sus scrofa)


name: structural constituent of postsynaptic actin cytoskeleton


name: IP6 transports from the nucleus to the ER lumen (Homo sapiens)


name: Allergen dependent IgE bound FCERI aggregation (Rattus norvegicus)


name: H(+) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (R)-noradrenaline + S-adenosyl-L-methionine => (R)-normetanephrine + H(+) + S-adenosyl-L-homocysteine


name: Caspase mediated cleavage of C-IAP1 (Sus scrofa)


name: 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O => ADP + H(+) + N-acetyl-D-muramate 6-phosphate


name: AJUBA binds centrosome-associated AURKA (Homo sapiens)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Caenorhabditis elegans)


name: TPI1 isomerizes GA3P to DHAP (Danio rerio)


name: gibberellin A34 + S-adenosyl-L-methionine = O-methyl gibberellin A34 + S-adenosyl-L-homocysteine


name: ADO oxidises 2AET to HTAU (Dictyostelium discoideum)


name: ATP + L-arginine => ADP + H(+) + N(omega)-phospho-L-arginine


name: a ganglioside GD1a + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GalNAc-GD1a + H(+) + UDP


name: docosanoate + O2 + reduced [NADPH--hemoprotein reductase] => 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: chloride(in) + formate(out) => chloride(out) + formate(in)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Caenorhabditis elegans)


name: Serine phosphorylation of STATs (Rattus norvegicus)


name: a fatty acid(out) + ADP + H(+) + phosphate => a fatty acid(in) + ATP + H2O


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Xenopus tropicalis)


name: NAD(+) <=> cyclic ADP-beta-D-ribose + H(+) + nicotinamide


name: Formation of the MLL1 complex (Mus musculus)


name: PA is converted to CDP-DAG by CDS2 (Rattus norvegicus)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Xenopus tropicalis)


name: 17beta-estradiol 17-sulfate(out) + 2 Na(+)(out) => 17beta-estradiol 17-sulfate(in) + 2 Na(+)(in)


name: NGF- and MAPK-dependent EGR1, EGR2 and EGR4 expression (Homo sapiens)


name: [thioredoxin]-disulfide + prostaglandin F2alpha => [thioredoxin]-dithiol + prostaglandin H2


name: HCMV C Nucleocapsid Translocation (Homo sapiens)


name: AMP + deoxycholoyl-CoA + diphosphate => ATP + CoA + deoxycholate


name: Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane (Homo sapiens)


name: TP53 family members bind PPP1R13B or TP53BP2 (Gallus gallus)


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Gallus gallus)


name: trans-Golgi Network Vesicle Scission (Drosophila melanogaster)


name: (3S)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+) => (1R,4S)-1-hydroxylimonen-2-one + NADPH + O2


name: Tenascins C, R, (X, N) bind fibronectin matrix (Gallus gallus)


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Sus scrofa)


name: (2S)-2-isopropylmalate(in) + sulfate(out) = (2S)-2-isopropylmalate(out) + sulfate(in)


name: F-actin capping protein is a heterodimer (Gallus gallus)


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Bos taurus)


name: ORC1 binds to H4K20me2 (Drosophila melanogaster)


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Mus musculus)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Rattus norvegicus)


name: p190RhoGAP binds Plexin-B1 (Danio rerio)


name: Recruitment of CstF to the CPSF Bound Pre-mRNA (Rattus norvegicus)


name: L-seryl-[protein] + pentanoyl-CoA => CoA + O-pentanoyl-L-seryl-[protein]


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Rattus norvegicus)


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Bos taurus)


name: phenyllactate dehydrogenase (NAD+) activity


name: N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: Phosphorylation of LIMK-1 by PAK (Homo sapiens)


name: SERPINB13 binds cathepsin L (Danio rerio)


name: Activated FGFR1 binds PLCG1 (Mus musculus)


name: 17beta-hydroxyestr-4-en-3-one + H(+) + NADPH <=> 17beta-hydroxy-5beta-estran-3-one + NADP(+)


name: Elongation of pre-rRNA transcript (Xenopus tropicalis)


name: indole-3-pyruvate imine dimer => chromopyrrolate + H(+) + NH4(+)


name: 8-oxo-dGDP + H2O = 8-oxo-dGMP + H(+) + phosphate


name: Activation of MT-MMPs by FURIN (Homo sapiens)


name: Expression of globin genes under control of the beta globin control region (Homo sapiens)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Bos taurus)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phosphocholine + cholesterol <=> (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: a quinol + oxaloacetate => (S)-malate + a quinone


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Danio rerio)


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Gallus gallus)


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)


name: 8-amino-8-demethylriboflavin + 2 S-adenosyl-L-methionine <=> 2 H(+) + roseoflavin + 2 S-adenosyl-L-homocysteine


name: PIAS1 SUMOylates THRB with SUMO1. (Rattus norvegicus)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Homo sapiens)


name: USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Sus scrofa)