name: ERBB2 TMD/JMD heterodimers trans-autophosphorylate (Homo sapiens)


name: AH2 + fusahexin + 6 H2O => A + D-alanine + D-allo-threonine + D-leucine + 2 L-leucine + L-proline


name: Recruitment of CDK11p58 to the centrosomes (Homo sapiens)


name: an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH => a (2S,3S)-flavan-3-ol + 2 NADP(+)


name: HSD17B1 hydrogenates E1 to EST17b (Canis familiaris)


name: indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose <=> 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP


name: delphinidin + UDP-alpha-D-galactose = delphinidin 3-O-beta-D-galactoside + H(+) + UDP


name: BRF1 Complex recruits RNA degradation activities (Homo sapiens)


name: GABA translocates from cytosol to mitochondrial matrix (Homo sapiens)


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe (Mus musculus)


name: H2O + L-threonyl-tRNA(Ser) <=> L-threonine + tRNA(Ser)


name: ATP + H2O + L-cysteine(in) = ADP + H(+) + L-cysteine(out) + phosphate


name: Autophosphorylation of PAK1 (Homo sapiens)


name: Phosphorylated TAK1 leaves activated TLR receptor complex (Gallus gallus)


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Sus scrofa)


name: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) => (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO2


name: a (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate + H(+) + NADPH => a [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate + NADP(+)


name: ATP + estrone 3-sulfate(out) + H2O <=> ADP + estrone 3-sulfate(in) + H(+) + phosphate


name: guaethol + O2 + reduced [NADH--hemoprotein reductase] => acetaldehyde + catechol + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: Release of PLCG from FCGR3A (Homo sapiens)


name: RUNX1 and FOXP3 stimulate the RSPO3 gene expression (Homo sapiens)


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Drosophila melanogaster)


name: RNA polymerase II CTD heptapeptide repeat Y1 kinase activity


name: HRASLS transfer acyl group from PC to PE to form NAPE (Mus musculus)


name: L-glutamate + O-phospho-L-serine <=> H(+) + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate


name: p-S54-PDE4B hydrolyses cAMP (Gallus gallus)


name: 2-oxoglutarate + [amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate => [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + L-glutamate


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Xenopus tropicalis)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Sus scrofa)


name: TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Mus musculus)


name: SMAD2/3:SMAD4 heterotrimer binds SP1 (Canis familiaris)


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Sus scrofa)


name: (S)-scoulerine + 2-oxoglutarate + O2 => (S)-3-O-demethylscoulerine + CO2 + formaldehyde + succinate


name: 28-norcastasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => 6-deoxo-28-norcastasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: DAG kinase produces phosphatidic acid from DAG (Plasmodium falciparum)


name: NTRK2-activated PI3K generates PIP3 (Homo sapiens)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Caenorhabditis elegans)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Drosophila melanogaster)


name: 9,12-cis-hexadecadienoic acid delta 15 desaturase activity


name: Interleukin-1 family are secreted (Danio rerio)


name: Tyrosinase oxidises tyrosine to dopaquinone (Sus scrofa)


name: a dolichyl D-xylosyl phosphate + L-seryl-[protein] => 3-O-(beta-D-xylosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)


name: Caspase-mediated cleavage of Lamin B1 (Mus musculus)


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Sus scrofa)


name: Tyrosine phosphorylation of CRMPs by Fes (Canis familiaris)


name: (2E,6E)-farnesol + CTP = (2E,6E)-farnesyl phosphate + CDP + H(+)


name: Cohesin binds PDS5 and WAPAL (Bos taurus)


name: a ganglioside Gal-GD1b + UDP-alpha-D-galactose <=> a ganglioside GalGal-GD1b + H(+) + UDP


name: an N(2)-(1-hydroxy-2-oxoethyl)-guanosine in RNA + H2O = a guanosine in RNA + glycolate + H(+)


name: malate(out) + 3 Na(+)(out) <=> malate(in) + 3 Na(+)(in)


name: ALPK1 phosphorylates TIFA (Rattus norvegicus)


name: (R)-lipoate(in) + 2 Na(+)(in) => (R)-lipoate(out) + 2 Na(+)(out)


name: CTP + pseudaminate <=> CMP-pseudaminate + diphosphate


name: RET tyrosine phosphorylation (Rattus norvegicus)


name: (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA => (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H2O


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Bos taurus)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Homo sapiens)


name: (R)-reticuline + NADP(+) <=> 1,2-dehydroreticuline + H(+) + NADPH


name: RDH13 reduces atRAL to atROL (Caenorhabditis elegans)


name: PINK1 is autophosphorylated (Sus scrofa)


name: a fatty acid + H(+) + N-acyl-sn-glycero-3-phosphoethanolamine => H2O + N,1-diacyl-sn-glycero-3-phosphoethanolamine


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Mus musculus)


name: 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine + AH2 => 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine + A + H2O


name: COMT transfers Met to DA to form 3MT (Homo sapiens)


name: Inhibitors bind and inhibit highly active BRAF mutants (Homo sapiens)


name: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH


name: GUK1 phosphorylates 6TGMP to 6TGDP (Caenorhabditis elegans)


name: CYCS binds to APAF1 (Xenopus tropicalis)


name: 3-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose = a neolactoside V(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: O-atom dealkylation of dextromethorphan (Sus scrofa)


name: RFC dissociates after sliding clamp formation on the C-strand of the telomere (Xenopus tropicalis)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Sus scrofa)


name: Activated FGFR2 phosphorylates FRS2 (Homo sapiens)


name: Active p38 MAPK phosphorylates MAPKAPK5 (Bos taurus)


name: H2O + L-threonyl-L-threonine => 2 L-threonine


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Mus musculus)


name: H2O + N(1)-acetylspermine <=> acetate + spermine


name: Interleukin-1 family are secreted (Sus scrofa)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + D-alanine + H2O => (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine


name: CYCS:APAF1 binds procaspase-9 (Gallus gallus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + isopentenyl diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate


name: Acidification of Tf:TfR1 containing endosome (Rattus norvegicus)


name: 19-hydroxy-9alpha,11alpha-methylene thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9alpha,11alpha-methylene thromboxane A2 + O2 + reduced [NADPH--hemoprotein reductase]


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Homo sapiens)


name: PPT1 hydrolyses palmitoylated proteins (Mus musculus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: geranylgeranyl diphosphate + L-cysteinyl-[protein] = diphosphate + S-geranylgeranyl-L-cysteinyl-[protein]


name: Caspase mediated cleavage of HIP-55 (Gallus gallus)


name: 3'-dephospho-CoA + ATP <=> ADP + CoA + H(+)


name: PI3K associates with phosphorylated GAB2 (Drosophila melanogaster)


name: depalmitoylation of eNOS (Saccharomyces cerevisiae)


name: PDCL promotes G-protein beta 5 folding (Rattus norvegicus)


name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA (Xenopus tropicalis)


name: Polyubiquitinated RUNX3 translocates to the cytosol (Rattus norvegicus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 O2 => (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E,19Z)-docosahexaenoate


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Canis familiaris)


name: DOLK phosphorylates DCHOL to DOLP (Rattus norvegicus)


name: HSF1 trimer translocates to the nucleus (Drosophila melanogaster)


name: L-lysyl-[protein] + octanoyl-[ACP] => H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]


name: 4-oxohex-2-enedioate + H(+) => 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Drosophila melanogaster)


name: Formation of eIF2:GDP:eIF2B intermediate (Homo sapiens)


name: cirsimaritin + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + salvigenin


name: Rap1 signal termination by Rap1GAPs (Mus musculus)


name: SPP1 (osteopontin) binds CD44 (Mus musculus)


name: FAM83B, (FAM83A, FAM83D) bind EGFR (Bos taurus)


name: 4-methylquinoline + A + H2O = 4-methylquinolin-2(1H)-one + AH2


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Caenorhabditis elegans)


name: diphosphate + tetradecanoyl-AMP => ATP + H(+) + tetradecanoate


name: 2-hydroxycyclohexan-1-one + H(+) + NADH => NAD(+) + trans-cyclohexane-1,2-diol


name: ADP-alpha-D-glucose + sn-glycerol 3-phosphate = 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + ADP + H(+)


name: GPIb:IX:V binds to VWF multimer:collagen (Homo sapiens)


name: Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) (Homo sapiens)


name: a dicarboxylate + ATP + CoA = AMP + diphosphate + omega-dicarboxyl-CoA


name: gamma-secretase cleaves p75NTR, releasing NRIF and TRAF6 (Homo sapiens)


name: 2 A + all-trans-zeta-carotene = 2 AH2 + all-trans-lycopene


name: (R)-carnitine(out) + Na(+)(out) <=> (R)-carnitine(in) + Na(+)(in)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)


name: BIL dissociates from GSTA1, FABP1 (Drosophila melanogaster)


name: C4 deamination of cytidine (Rattus norvegicus)


name: L-aspartate + NADP(+) <=> H(+) + iminosuccinate + NADPH


name: ATP + L-amino acyl-L-threonyl-[protein] <=> (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + ADP + H(+) + phosphate


name: Binding of SHC1 to insulin receptor (Sus scrofa)


name: NEU3 hydrolyzes Neu5Ac from glycoconjugates (Mus musculus)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Homo sapiens)


name: Translocation of CARMA1 to Plasma membrane (Sus scrofa)


name: Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane (Homo sapiens)


name: 3-epi-6-deoxocathasterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 6-deoxotyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-dehydrosphinganine + NADPH + H+ => sphinganine + NADP+ (Gallus gallus)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Drosophila melanogaster)


name: mRNA2 is translated to Spike (Homo sapiens)


name: arginine + H2O => ornithine + urea [ARG2] (Bos taurus)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Rattus norvegicus)


name: ergothioneine(out) + Na(+)(out) = ergothioneine(in) + Na(+)(in)


name: RND3 binds GTP (Schizosaccharomyces pombe)


name: SHC1 dissociates from integrin alphaIIb beta3 (Mus musculus)


name: A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+) => 4-chloro-L-lysine + AH2 + O2


name: Calcineurin binds and dephosphorylates NFAT (Drosophila melanogaster)


name: AMP + diphosphate + octanoyl-[ACP] => ATP + holo-[ACP] + octanoate


name: 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH + O2 = 9alpha-hydroxy-3-oxochola-1,4-dien-22-oyl-CoA + H2O + NAD(+)


name: 2 Na(+)(in) + pregnenolone sulfate(in) => 2 Na(+)(out) + pregnenolone sulfate(out)


name: MRN complex binds shortened telomeres (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O => a fatty acid + a monoacyl-sn-glycero-3-phosphocholine + H(+)


name: AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Sus scrofa)


name: Exocytosis of Proactivator polypeptide (Canis familiaris)


name: 1-chloro-2-nitrobenzene + NADH + O2 => 3-chlorocatechol + NAD(+) + nitrite


name: p-PKR dimer phosphorylates ILF3:ILF2 (Canis familiaris)


name: acetyl-CoA + octan-1-ol = CoA + octyl acetate


name: GDP-beta-L-colitose + NAD(+) => GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + H(+) + NADH


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Bos taurus)


name: NAD(+) + UDP-alpha-D-glucuronate => CO2 + NADH + UDP-beta-L-threo-pentopyranos-4-ulose


name: ARSA removes sulfate from SM3 (Mus musculus)


name: acetyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO2 + 4 CoA + orcinol


name: RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Saccharomyces cerevisiae)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Drosophila melanogaster)


name: Kinesins move along microtubules consuming ATP (Canis familiaris)


name: N(omega),N('omega)-dimethyl-L-arginine + pyruvate => 5-(3,3'-dimethylguanidino)-2-oxopentanoate + L-alanine


name: 2 L-ascorbate + N-octanoylglycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-octanoyl-(2S)-hydroxyglycine


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Canis familiaris)


name: Association of Cyclin A with the APC/C (Bos taurus)


name: ATP + cholate(in) + H2O => ADP + cholate(out) + H(+) + phosphate


name: FABP5:atRA translocates from cytosol to nucleoplasm (Canis familiaris)


name: 1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) => a 2-demethylmenaquinol + CO2 + diphosphate


name: (2E,6E)-farnesyl diphosphate + 3,5-dimethylorsellinate <=> (3R)-3-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylate + diphosphate + H(+)


name: Activation of claspin (Canis familiaris)


name: a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GT1b + CMP + H(+)


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Bos taurus)


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Mus musculus)


name: Caspase-mediated cleavage of MST3 (Bos taurus)


name: (20S)-ginsenoside R1 + H2O = (20S)-ginsenoside Rg1 + D-xylose


name: butanoyl-CoA + FAD + H(+) => (2E)-butenoyl-CoA + FADH2


name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Schizosaccharomyces pombe)


name: FAHD1 dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)


name: "type I site-specific deoxyribonuclease"


name: 2 chloride(in) + sulfate(out) = 2 chloride(out) + sulfate(in)


name: L-gulono-1,4-lactone + O2 = H2O2 + L-xylo-hex-3-ulonolactone


name: 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate


name: Initial activation of proMMP1 (Mus musculus)


name: CBFB binds RUNX3 (Caenorhabditis elegans)


name: Movement of clathrin coated vesicles into early endosome (Canis familiaris)


name: Fibronectin degradation by ADAM8 (Canis familiaris)


name: 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + NADP(+)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GA2 (d18:1(4E)) + H(+) + UDP


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Saccharomyces cerevisiae)


name: (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + glycine + reduced [electron-transfer flavoprotein] => (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + H(+) + oxidized [electron-transfer flavoprotein] + sarcosine


name: H2O + mycothiol S-conjugate <=> 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + an N-acetyl-L-cysteine-S-conjugate


name: IL6R binds IL6R inhibitors (Canis familiaris)


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Mus musculus)


name: Activated FGFR1 binds FLRT1,2,3 (Drosophila melanogaster)


name: N(2)-(1-hydroxy-2-oxopropyl)-GMP => GMP + methylglyoxal


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Homo sapiens)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (9Z)-octadec-9-en-12-ynoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) = 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)


name: dehydrocitreoisocoumarin + H2O + holo-[ACP] => 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP]


name: UDP-alpha-D-glucose + vitexin <=> H(+) + UDP + vitexin 2''-O-beta-D-glucoside


name: voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization


name: PINK1 phosphorylates Ub on MOM proteins (Homo sapiens)


name: UCKL1 phosphorylates urindine, cytidine (Schizosaccharomyces pombe)


name: Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Caenorhabditis elegans)


name: AFG3L2 binds mitochondrial matrix proteins (Drosophila melanogaster)


name: (3S)-hydroxy-(9Z-octadecenoyl)-CoA => (2E,9Z)-octadecadienoyl-CoA + H2O


name: 4alpha-carboxyzymosterol + NAD(+) <=> CO2 + NADH + zymosterone


name: a (2R)-2-hydroxycarboxylate + NAD(+) <=> a 2-oxocarboxylate + H(+) + NADH


name: urocanate + H2O => 4-imidazolone-5-propionate (Caenorhabditis elegans)


name: (2R,3R,5S,6R)-6-(methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + 5'-deoxyadenosine + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine => (2R,3R,5S)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + AH2 + 2 S-adenosyl-L-methionine


name: PKC autophosphorylates (Canis familiaris)


name: 2-oxoglutarate + hexyl sulfate + O2 = CO2 + H(+) + hexanal + succinate + sulfate


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Canis familiaris)


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Sus scrofa)


name: Phosphorylation and activation of Ezrin (Drosophila melanogaster)


name: ABC-type taurine transporter transporter activity


name: 9alpha-copalyl diphosphate + H2O => aphidicolan-16beta-ol + diphosphate


name: a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine => a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: 9H-fluoren-9-ol + NADP(+) = 9H-fluoren-9-one + H(+) + NADPH


name: RNase H-mediated degradation of the template strand (Homo sapiens)


name: ATP + beta-D-ribosylnicotinate => ADP + H(+) + nicotinate beta-D-ribonucleotide


name: heptadecasphing-4-enine + tetracosenoyl-CoA => CoA + H(+) + N-tetracosenoyl-heptadecasphing-4-enine


name: (Z)-2-(indol-3-yl)-1-thioacetohydroximate + UDP-alpha-D-glucose = (Z)-indolylmethyl desulfoglucosinolate + UDP


name: GSTZ1 isomerizes 4-MAA (Rattus norvegicus)


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-pyrethrolone => CoA + pyrethrin II


name: cucurbitadienol + O2 + reduced [NADPH--hemoprotein reductase] <=> 11-hydroxycucurbitadienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O => D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate


name: CA4:Zn2+ hydrates CO2 to HCO3- (Canis familiaris)


name: D-erythrose 4-phosphate + dihydroxyacetone phosphate <=> D-sedoheptulose 1,7-bisphosphate


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NADP(+) <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH


name: 2,3-bis-O-(geranylfarnesyl)-sn-glycerol 1-phosphate + diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-3-(O-farnesylgeranyl)glycerol 1-phosphate


name: Elastin degradation by elastin-degrading extracellular proteinases (Homo sapiens)


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate <=> 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: cis-beta-D-glucosyl-2-hydroxycinnamate + H2O <=> beta-D-glucose + cis-2-coumarate


name: abieta-7,13-dien-18-ol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = abieta-7,13-dien-18-oate + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: uridine(13) in tRNA => pseudouridine(13) in tRNA


name: S-adenosyl-L-methionine + salicylate => methyl salicylate + S-adenosyl-L-homocysteine


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Mus musculus)


name: transcription regulator inhibitor activity


name: (5Z,8Z,11Z,14Z)-eicosatetraenedioate + 2 H(+) + NADH => 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O + NAD(+)


name: BBC3 gene expression is stimulated by FOXO3,(FOXO1) (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = H(+) + hexadecanoate + hexadecanoyl-glycero-3-phospho-(1D-myo-inositol)


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Xenopus tropicalis)


name: Thr-180 of ULK1 is phosphorylated (Bos taurus)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: H2O + phosphoenolpyruvate => phosphate + pyruvate


name: 27-hydroxysterol binds ESR1, ESR2 (Gallus gallus)


name: Journey of cargo through Golgi complex (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1-(9Z)-octadecenoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + O2 + reduced [NADPH--hemoprotein reductase] <=> (20S)-ginsenoside C-K + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: lactate + H+ [cytosol] <=> lactate + H+ [extracellular] (Gallus gallus)


name: 3 Na(+)(out) + phosphate(out) => 3 Na(+)(in) + phosphate(in)


name: AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr) => ATP + L-tyrosine + tRNA(Tyr)


name: 2-deoxy-L-scyllo-inosose + L-glutamine = 2-deoxy-scyllo-inosamine + 2-oxoglutaramate


name: CoA + H(+) + N-acyl-15-methylhexadecasphinganine => 15-methylhexadecasphinganine + a fatty acyl-CoA


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Caenorhabditis elegans)


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + H2O => (9Z)-hexadecenoate + 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + H(+)


name: AP1G2 binds HGS and CHMP2A (Canis familiaris)


name: 3-amino-5-hydroxybenzoate + ATP + holo-[aryl-carrier protein] = 3-amino-5-hydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate


name: (+)-cis-trans-nepetalactol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 7-deoxyloganetate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: MECP2:SIN3A complex binds GRIA2 gene promoter (Homo sapiens)


name: Activation of PAK by Rac1 (Homo sapiens)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: ERK1/2/5 activate RSK1/2/3 (Saccharomyces cerevisiae)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate => 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Danio rerio)


name: PC is converted to PS by PTDSS1 (Xenopus tropicalis)


name: IL12B:IL12B translocates from ER lumen to the extracellular region (Bos taurus)


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Drosophila melanogaster)


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Mus musculus)


name: TMED2:TMED10 tetramer binds GPI anchored proteins (Mus musculus)


name: p-PKR dimer phosphorylates MKK6 (Sus scrofa)


name: H(+) + NADH + O2 + quinolin-4-ol => H2O + NAD(+) + quinoline-3,4-diol


name: 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CoA <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + acetyl-CoA


name: Phospho-STAT3 binds the promoter of the CEBPB gene (Homo sapiens)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Mus musculus)


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + O2 + reduced [NADPH--hemoprotein reductase] => 5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 2 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = a Delta(14) steroid + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: AH2 + O2 + verruculide C <=> A + H2O + verruculide C epoxide


name: UBA1 adenylates ubiquitin in the cytosol (Danio rerio)


name: USP3,SAGA deubiquitinate Histone H2A,H2B (Canis familiaris)


name: a ganglioside GP1calpha (d18:1(4E)) + CMP + H(+) => a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: PNPLA4 hydrolyzes TAG (Canis familiaris)


name: Formation of PPAT dimers (Gallus gallus)


name: 2,2-dimethylpropanal + hydrogen cyanide = (2S)-2-hydroxy-3,3-dimethylbutanenitrile


name: Phosphorylation of PKC theta (Dictyostelium discoideum)


name: L-homocysteine <=> 2-aminobut-2-enoate + H(+) + hydrogen sulfide


name: guanosine(1370) in 16S rRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(1370) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose <=> 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: Ubiquitinated Orc1 is degraded by the proteasome (Homo sapiens)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Plasmodium falciparum)


name: 2-hydroxy-3-methylbutanoyl-CoA + CO2 + succinate => 2-oxoglutarate + 3-methylbutanoyl-CoA + O2


name: USP17 deubiquitinates SUDS3 (Mus musculus)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Canis familiaris)


name: SREBP1A,1C,2 translocates to the nucleus (Xenopus tropicalis)


name: FMO3:FAD N-oxidises TMA to TMAO (Mus musculus)


name: (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + NADPH => (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate => 14-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+) => a very-long-chain 3-oxoacyl-CoA + H(+) + NADH


name: 1,3-bisphosphoglycerate + NADH + H+ <=> glyceraldehyde 3-phosphate + NAD+ + phosphate (Gallus gallus)


name: KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Bos taurus)


name: (2E,6E)-farnesyl diphosphate => (+)-(E)-beta-caryophyllene + diphosphate


name: NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: SYK binds to integrin alphaIIb beta3 (Gallus gallus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H(+)


name: NAGLU hydrolyses Heparan sulfate chain(4) (Dictyostelium discoideum)


name: RHOQ GEFs activate RHOQ (Canis familiaris)


name: ERCC5 and RPA bind TC-NER site (Bos taurus)


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Canis familiaris)


name: oxalate(out) + sulfate(in) => oxalate(in) + sulfate(out)


name: SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Schizosaccharomyces pombe)


name: EGFRvIII does not bind CBL (Homo sapiens)


name: Formation of the CTF18-RFC(7s) complex (Drosophila melanogaster)


name: (2E,6E)-farnesal + H2O + NAD(+) => (2E,6E)-farnesoate + 2 H(+) + NADH


name: KRAS4B is phosphorylated on serine 181 (Gallus gallus)


name: CES1,CES2 hydrolyze ASA- to ST (Gallus gallus)


name: Activated FGFR2 phosphorylates FRS3 (Gallus gallus)


name: an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O <=> an N-acyl-(4R)-4-hydroxysphinganine + H(+) + mannosyldiinositol-1-phosphate


name: (2E)-tetradecenoyl-CoA + H(+) + NADPH = NADP(+) + tetradecanoyl-CoA


name: 2 Fe(III)-[cytochrome c] + L-ascorbate = 2 Fe(II)-[cytochrome c] + 2 H(+) + L-dehydroascorbate


name: RAC1:GTP:FMNL1 binds profilin:G-actin (Homo sapiens)


name: PLK3 phosphorylates TP53 (Canis familiaris)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Mus musculus)


name: Cleavage of Procaspase-3 by the apoptosome (Homo sapiens)


name: Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA (Bos taurus)


name: CBX4 SUMOylates BMI1 in PRC1 with SUMO1 (Gallus gallus)


name: 3-hydroxy-L-kynurenine + H2O <=> 3-hydroxyanthranilate + H(+) + L-alanine


name: a 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA => a 1-acyl-sn-glycero-3-phosphate + octadecanoyl-CoA


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Drosophila melanogaster)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Homo sapiens)


name: TFAP2C homodimer binds MYC and KDM5B (Homo sapiens)


name: Caspase-mediated cleavage of Desmoglein 1 (Caenorhabditis elegans)


name: GRB2:SOS1 complex binds to the active receptor (Homo sapiens)


name: Formation of AT-AC B Complex (Drosophila melanogaster)


name: Carboxypeptidase E hydrolyzes Insulin(57-89) to yield C-peptide (Insulin(57-87)) (Homo sapiens)


name: C-terminal Hh fragments are bound by lectins (Canis familiaris)


name: 2 H(+)(in) + nitrate + ubiquinol-8 => 2 H(+)(out) + H2O + nitrite + ubiquinone-8


name: 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADH => 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+)


name: H2O + NAD(+) + trimethylamine = 2 H(+) + NADH + trimethylamine N-oxide


name: YOD1 binds VCP (Schizosaccharomyces pombe)


name: HDACs deacetylate p-STAT3 dimers (Homo sapiens)


name: ADP + H(+) + N-acetyl-D-muramate 6-phosphate => 1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Dictyostelium discoideum)


name: gilteritinib-resistant FLT3 mutants don't bind gilteritinib (Homo sapiens)


name: [(1->4)-alpha-D-glucosyl](n+1) + ADP + H(+) => [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose


name: SLC22A1 transports Cipro into hepatic cell (Xenopus tropicalis)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GM1b (d18:1(4E)) + CMP + H(+)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IIA => a 2-acyl-sn-glycero-3-phosphocholine + lipid IIB


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Sus scrofa)


name: H2O + pentanoate ester <=> an aliphatic alcohol + H(+) + pentanoate


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Xenopus tropicalis)


name: nsp15 cleaves viral poly(U)-RNA (Homo sapiens)


name: SAICAR => AICAR + Fumarate (Saccharomyces cerevisiae)


name: AFG3L2 binds mitochondrial inner membrane proteins (Saccharomyces cerevisiae)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> diphosphate + variecoladiene


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Bos taurus)


name: (2S)-naringenin + 2-oxoglutarate + O2 <=> apigenin + CO2 + H(+) + H2O + succinate


name: SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Rattus norvegicus)


name: NTPDase3 hydrolyzes nucleoside triphosphates (Sus scrofa)


name: EHD proteins interact with Rabenosyn-5 (Xenopus tropicalis)


name: 2-methylpropanoyl-CoA + H2O = 2-methylpropanoate + CoA + H(+)


name: (3R)-hydroxy-(9Z)-hexadecenoyl-[ACP] = (2E,9Z)-hexadecadienoyl-[ACP] + H2O


name: UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Mus musculus)


name: 7-hydroxyquinolin-2(1H)-one + AH2 => A + H2O + quinolin-7-ol


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: [deoxyhypusine synthase]-L-lysine + dehydrospermidine <=> [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine


name: RHOV binds effectors at the plasma membrane (Sus scrofa)


name: RUNX3 translocates to the nucleus (Canis familiaris)


name: H2O + quercitrin => L-rhamnopyranose + quercetin


name: (S)-malate + a quinone = a quinol + oxaloacetate


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Sus scrofa)


name: anthranilate + benzoyl-CoA => CoA + N-benzoylanthranilate


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Homo sapiens)


name: CEBPA mRNA is translated to yield CEBPA protein (Homo sapiens)


name: Autoproteolytic cleavage of Hh precursors (Drosophila melanogaster)


name: (S)-sec-butylamine + H2O + NAD(+) = butan-2-one + H(+) + NADH + NH4(+)


name: Formation of N-glucuronides (Dictyostelium discoideum)


name: H2O + N-(4-aminobutyl)-3-aminopropanal + NAD(+) => 2 H(+) + N-(2-carboxyethyl)putrescine + NADH


name: MIA2 and MIA3 load procollagen VII into COPII vesicles (Sus scrofa)


name: N-(dodecanoyl)-sphing-4-enine-1-phosphocholine <=> choline + N-dodecanoyl-sphing-4-enine-1,3-cyclic phosphate


name: PRKD1,2,3 phosphorylates CERT1-2 (Caenorhabditis elegans)


name: Co-precorrin-5A + H2O <=> acetaldehyde + Co-precorrin-5B + H(+)


name: H2O + octanoyl-[ACP] <=> H(+) + holo-[ACP] + octanoate


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Drosophila melanogaster)


name: SENP1,2,5 proteolytically process SUMO1 (Rattus norvegicus)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Dictyostelium discoideum)


name: cyclopentanone + H(+) + NADPH + O2 = 5-valerolactone + H2O + NADP(+)


name: H(+) + indole-3-pyruvate => CO2 + indole-3-acetaldehyde


name: 2-arylpropionate + CO2 => 2-aryl-2-methylmalonate + H(+)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Gallus gallus)


name: 3-oxododecanoate + H(+) => 2-undecanone + CO2


name: asc-C7-CoA + O2 => asc-DeltaC7-CoA + H2O2


name: Release of platelet secretory granule components (Xenopus tropicalis)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Drosophila melanogaster)


name: 1-acyl LPS is acylated to PS by LPSAT (Caenorhabditis elegans)


name: 2 GTP <=> 3',3'-c-di-GMP + 2 diphosphate


name: EPO:p-EPOR:p-JAK2:LYN:IRS2 binds CRKL:RAPGEF1 (Homo sapiens)


name: [translation elongation factor 2]-phosphate + ADP + H(+) => [translation elongation factor 2] + ATP


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycero-3-phospho-1D-myo-inositol => 2 a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: (2E,6E)-farnesyl diphosphate = diphosphate + gamma-humulene


name: losartan + UDP-alpha-D-glucuronate => losartan-2-N-beta-D-glucuronide + UDP


name: (R)-carnitine + an acyl-CoA => CoA + O-acyl-(R)-carnitine


name: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O


name: USP17 deubiquitinates SUDS3 (Saccharomyces cerevisiae)


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Sus scrofa)


name: (-)-menthol + H(+) + NADPH + O2 = 1,4-menthane-3,8-diol + H2O + NADP(+)


name: p-STAT3 dimer translocates from cytosol to nucleoplasm (Homo sapiens)


name: BCL2 binds BCL2 antagonists (Danio rerio)


name: pyruvate + taurine <=> L-alanine + sulfoacetaldehyde


name: (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase] => 4-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3',5'-cyclic AMP(in) + ATP + H2O => 3',5'-cyclic AMP(out) + ADP + H(+) + phosphate


name: (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H2O => (3R)-hydroxy-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA


name: SHC1-2 bound to MET recruits GRB2:SOS1 (Homo sapiens)


name: CD59 inhibits MAC formation (Canis familiaris)


name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript (Homo sapiens)


name: (3S)-hydroxytetradecanoyl-CoA + H2O = (3S)-hydroxytetradecanoate + CoA + H(+)


name: SARS-COV 7a translocates to the late endosome membrane (Homo sapiens)


name: p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor (Bos taurus)


name: C3d-complexed antigen binds to complement receptor (Canis familiaris)


name: H(+)(in) + L-glutamate(in) => H(+)(out) + L-glutamate(out)


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Homo sapiens)


name: carnosine(out) + H(+)(out) = carnosine(in) + H(+)(in)


name: an N-acylneuraminate 9-phosphate + H2O => an N-acylneuraminate + phosphate


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Sus scrofa)


name: Arachidonic acid is hydroxylated to 20-HETE by CYP(3) (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine


name: cholate + NAD(+) => 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH


name: RHOBTB3 hydrolyzes ATP (Rattus norvegicus)


name: cumene hydroperoxide + 2 glutathione <=> 2-phenylpropan-2-ol + glutathione disulfide + H2O


name: a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H(+) + L-tyrosine => a 3'-end 2'-deoxyribonucleotide-3'-(L-tyrosyl phosphate)-DNA + H2O


name: ATPase-coupled 2-aminoethylphosphonate transporter activity


name: (2-aminoethyl)phosphonate(out) + ATP + H2O = (2-aminoethyl)phosphonate(in) + ADP + H(+) + phosphate


name: ISGylation of DDX58 (Plasmodium falciparum)


name: 3-hydroxy-3-methylglutarate + succinyl-CoA <=> (3S)-hydroxy-3-methylglutaryl-CoA + succinate


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Sus scrofa)


name: 6 (S)-methylmalonyl-CoA + 12 H(+) + malonyl-CoA + 5 NADPH = 7 CO2 + 7 CoA + 2 H2O + 5 NADP(+) + narbonolide


name: Na+/H+ exchanger transport (at cell membrane) (Mus musculus)


name: H(+) + oleanolate 3-O-beta-D-glucoside + UDP => oleanolate + UDP-alpha-D-glucose


name: AKT phosphorylates FOXO3 downstream of FLT3  (Drosophila melanogaster)


name: Phosphorylated Cdc6 is exported from the nucleus (Caenorhabditis elegans)


name: 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4beta-methylzymosterol-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2 H(+) + H2O + N-carbamoylsarcosine => CO2 + NH4(+) + sarcosine


name: 1,3,7-trimethylurate + ubiquinol-0 => caffeine + H2O + ubiquinone-0


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Homo sapiens)


name: LDHAL6B reduces PYR to LACT (Canis familiaris)


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Homo sapiens)


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Mus musculus)


name: a 1,3-diacyl-sn-glycerol + a monoacyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Homo sapiens)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Mus musculus)


name: 3-O-[beta-D-GlcA-(1->3)-beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP => 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-glucuronate


name: 2-dehydro-3-deoxy-D-galactonate + H2O => D-galactonate


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Gallus gallus)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Xenopus tropicalis)


name: (indol-3-yl)acetate + H(+) => CO2 + skatole


name: FA anion diffuses laterally to UCP (Xenopus tropicalis)


name: 2-AG hydrolysis to arachidonate by MAGL (Rattus norvegicus)


name: APRT catalyzes the conversion of adenine to AMP (Mus musculus)


name: EBP isomerizes ZYMSTNL to LTHSOL (Mus musculus)


name: Translocation of WWTR1 (TAZ) to the nucleus (Canis familiaris)


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Mus musculus)


name: D-xylono-1,5-lactone + H(+) + NADPH => D-xylose + NADP(+)


name: AMP + benzoyl-CoA + H(+) => benzoyl-AMP + CoA


name: (1R,4R)-dihydrocarvone + H(+) + NADH => (1R,2R,4R)-dihydrocarveol + NAD(+)


name: NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP (Canis familiaris)


name: NaS1 co-transports sulphate and a sodium ion (Danio rerio)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Homo sapiens)


name: (1-deoxy-D-fructos-1-yl)amine + glyoxylate + H2O2 => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Rattus norvegicus)


name: H2O + L-homoseryl-tRNA(Lys) <=> H(+) + L-homoserine + tRNA(Lys)


name: Expression of Farnesyl Diphosphate Synthase (FDPS) (Homo sapiens)


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Sus scrofa)


name: 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate <=> H2O + xanthurenate


name: ent-cassa-12,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => ent-3beta-hydroxycassa-12,15-dien-2-one + 3 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 5-methyl-CTP + H2O <=> 5-methyl-CMP + diphosphate + H(+)


name: Formation of DSIF complex  (Drosophila melanogaster)


name: L-pipecolate + NADP(+) <=> Delta(1)-piperideine-2-carboxylate + H(+) + NADPH


name: atROL binds RBP1 (parenchymal cell) (Drosophila melanogaster)


name: epothilone D + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> epothilone B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 5-hydroxy-3-methyl-O-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine => 5-hydroxy-3-methyl-L-tyrosine + S-adenosyl-L-methionine


name: 1-octadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-octadecanoyl-sn-glycero-3-phosphocholine + dodecanoate + H(+)


name: (15Z)-tetracosenoyl-CoA + sphinganine => CoA + H(+) + N-(15Z-tetracosenoyl)-sphinganine


name: H(+) + N-ethylmaleimide + NADH => N-ethylsuccinimide + NAD(+)


name: G-protein alpha subunit is inactivated (Caenorhabditis elegans)


name: The COG complex binds RABs at the Golgi membrane (Gallus gallus)


name: STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Bos taurus)


name: PP2A dephosphorylates inactive RAFs (Mus musculus)


name: Growth hormone receptor dimerizes (Rattus norvegicus)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Xenopus tropicalis)


name: H2O + triuret => 1-carboxybiuret + NH4(+)


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Dictyostelium discoideum)


name: 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Rattus norvegicus)


name: 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + CoA => a long-chain fatty acyl-CoA + alpha,alpha-trehalose


name: ethylenediaminetriacetate + FMNH2 + O2 = ethylenediaminediacetate + FMN + glyoxylate + H(+) + H2O


name: D-galactosamine 6-phosphate <=> alpha-D-galactosamine 1-phosphate


name: Transport of Antigen peptide in to ER (Bos taurus)


name: Pol II elongation complex moves on the template as transcript elongates (Xenopus tropicalis)


name: NH4(+) + sym-homospermidine => 2 putrescine


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Homo sapiens)


name: anthranilate + S-adenosyl-L-methionine <=> H(+) + N-methylanthranilate + S-adenosyl-L-homocysteine


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Dictyostelium discoideum)


name: dec-9-enoyl-[ACP] + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = dec-9-ynoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PGLYRP1 binds bacterial peptidoglycan (Bos taurus)


name: alpha-D-glucose + ATP <=> ADP + alpha-D-glucose 6-phosphate + H(+)


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Rattus norvegicus)


name: COX15 transforms heme O to heme A (Dictyostelium discoideum)


name: (2S,3S)-versiconal hemiacetal acetate + H2O <=> (2S-3S)-versiconal hemiacetal + acetate + H(+)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Canis familiaris)


name: D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate => beta-D-fructose 1,6-bisphosphate


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NAD(+) = CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADH


name: a ganglioside Ac-O-7-GD3(d18:1(4E)) => a ganglioside Ac-O-8-GD3(d18:1(4E))


name: lupan-3beta,20-diol = (S)-2,3-epoxysqualene + H2O


name: L-ascorbate + O2 + tyramine => (R)-octopamine + H2O + L-dehydroascorbate


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Caenorhabditis elegans)


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Schizosaccharomyces pombe)


name: (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase] <=> 3beta-hydroxycostunolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CDKN1B is phosphorylated in response to estrogen (Gallus gallus)


name: CDC42:GTP binds PAK2 (Rattus norvegicus)


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)


name: SYK is a substrate for JAK1 (Sus scrofa)


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + 5 H(+) + 3 O2 + 6 reduced [adrenodoxin] = (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + 4 H2O + 6 oxidized [adrenodoxin]


name: 19-(4-hydroxyphenyl)nonadecanoyl-[4-hydroxyphenylalkanoate synthase] + 9 CO2 + 9 CoA + 9 H2O + 18 NADP(+) => 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 27 H(+) + 9 malonyl-CoA + 18 NADPH


name: [(1->3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose => [(1->3)-alpha-D-glucosyl](n+1) + H(+) + UDP


name: CoA + H(+) + S-(2-acetamidoethyl)-L-cysteine => acetyl-CoA + S-(2-aminoethyl)-L-cysteine


name: p130 (RBL2) associates with MuvB to form DREAM complex (Sus scrofa)


name: ARL2:GTP binds ARL2BP (Rattus norvegicus)


name: (2S)-hesperetin + UDP-alpha-D-glucose <=> (2S)-hesperetin 7-O-beta-D-glucoside + H(+) + UDP


name: 7alpha-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TDG excises 5-formylcytosine (Sus scrofa)


name: Trans-autophosphorylation of ERBB4 homodimers (Mus musculus)


name: H(+)(out) + L-alanyl-L-proline(out) => H(+)(in) + L-alanyl-L-proline(in)


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Homo sapiens)


name: (S)-cis-N-methyltetrahydrothalifendine + O2 + reduced [NADPH--hemoprotein reductase] => 7-hydroxy-8-methoxy-11-methyl-17,19-dioxa-11-azatetracyclo[12.7.0.0(4,9).0(16,20)]henicosa-1(21),4(9),5,7,14,16(20)-hexaen-2-one + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CHEK2 phosphorylates TTC5 (Canis familiaris)


name: coproporphyrinogen III + 3 O2 <=> coproporphyrin III + 3 H2O2


name: Adenylate cyclase converts ATP into cyclic AMP (Dictyostelium discoideum)


name: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: oxidoreductase activity, acting on CH or CH2 groups


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Dictyostelium discoideum)


name: H2O + monoacyl-sn-glycero-3-phosphate = a monoacylglycerol + phosphate


name: NOTCH1 t(7;9)(NOTCH1:M1580_K2555) does not bind JAG1 (Homo sapiens)


name: eNOS:Caveolin-1 complex binds to Nostrin (Mus musculus)


name: Opioid receptors bind opioid peptides (Xenopus tropicalis)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Mus musculus)


name: Activated FGFR2 binds PLCG1 (Rattus norvegicus)


name: glucose-6-phosphate dehydrogenase (coenzyme F420) activity


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 => N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate


name: eicosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-eicosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Bos taurus)


name: (E)-(indol-3-yl)acetaldehyde oxime <=> (indol-3-yl)acetonitrile + H2O


name: A + chloramphenicol + 2 H2O => AH2 + alpha-N-dichloroacetyl-p-aminophenylserinol + 2 O2


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Sus scrofa)


name: SRD5A2 binds SRD5A2 inhibitors (Sus scrofa)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Sus scrofa)


name: Unfolded substrate in LAMP2a multimeric complex binds HSPA8 (Homo sapiens)


name: 3,6-anhydro-alpha-L-galactopyranose + H2O + NAD(+) <=> 3,6-anhydro-L-galactonate + 2 H(+) + NADH


name: 2-oxosuccinamate + H2O <=> NH4(+) + oxaloacetate


name: 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate => 2'-deamino-2'-hydroxyneamine + 2-oxoglutarate


name: Recruitment of SLP-76 to Gads (Canis familiaris)


name: (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-eicosatrienoate => (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2


name: ATP + benzoate + H(+) = benzoyl-AMP + diphosphate


name: adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)


name: H2O + L-kynurenine = anthranilate + H(+) + L-alanine


name: H2O + methylamine + 2 oxidized [amicyanin] => formaldehyde + 2 H(+) + NH4(+) + 2 reduced [amicyanin]


name: TPX2 binds AURKA at centrosomes (Xenopus tropicalis)


name: carboxyphosphate + NH4(+) <=> carbamate + 2 H(+) + phosphate


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine


name: 2 Na(+)(out) + taurohyodeoxycholate(out) <=> 2 Na(+)(in) + taurohyodeoxycholate(in)


name: H(+) + hydroxylamine + L-asparagine = beta-L-aspartylhydroxamate + NH4(+)


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 18-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: ZNF423 binds EBF2 at EBF2-target gene loci (Homo sapiens)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Xenopus tropicalis)


name: USP49 deubiquitinates H2B (Dictyostelium discoideum)


name: (10bS,4aR)-noroxomaritidine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 4'-O-methylnorbelladine + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-hydroxy-3-methylhexadecanoyl-CoA + CO2 + succinate => 2-oxoglutarate + 3-methylhexadecanoyl-CoA + O2


name: WIP binds WASP,N-WASP, activating them (Sus scrofa)


name: Addition of galactose to Core 6 glycoprotein (Canis familiaris)


name: Nectin-1:Nectin-4 trans heterodimer formation (Bos taurus)


name: G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Canis familiaris)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Mus musculus)


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O => (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+)


name: 3,17-didehydrostemmadenine + H2O + NADPH <=> (16R)-deshydroxymethyl-stemmadenine + formate + NADP(+)


name: AMP + diphosphate + IC-asc-C9-CoA => ATP + CoA + IC-asc-C9


name: H2O + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) => acetate + alpha-D-glucosaminyl-[heparan sulfate](n)


name: [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine => L-glutamyl-[protein] + S-adenosyl-L-methionine


name: CTP + H(+) + N(5)-phospho-L-glutamine => diphosphate + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine


name: type 2 melanin-concentrating hormone receptor binding


name: 3-oxo-3-ureidopropanoate + H2O <=> H(+) + malonate + urea


name: Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix (Homo sapiens)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Gallus gallus)


name: methylmalonate semialdehyde + NAD+ + CoA => propionyl-CoA + CO2 + NADH + H+ (Mus musculus)


name: H2O + L-tryptophan => indole + NH4(+) + pyruvate


name: (2S)-3-phenyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2 => N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2


name: POLD,POLE complete replication of damaged DNA after TLS (Homo sapiens)


name: ATP + GTP <=> diphosphate + pppGp(2'-5')A


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 11beta,17beta-dihydroxyandrost-4-ene-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Rattus norvegicus)


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Sus scrofa)


name: [protein]-dithiol + NADP(+) = [protein]-disulfide + H(+) + NADPH


name: Association of procollagen type X (Caenorhabditis elegans)


name: Glypican-1 (GPC1) binds SLIT2 (Drosophila melanogaster)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Mus musculus)


name: Recruitment of TRAF6 to CBM complex by binding to MALT1 (Homo sapiens)


name: Addition of nucleotides between position +11 and +30 (Xenopus tropicalis)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Saccharomyces cerevisiae)


name: (2R)-2-hydroperoxydodecanoate + H(+) = CO2 + H2O + undecanal


name: (+-)-pavine + S-adenosyl-L-methionine => H(+) + N-methylpavine + S-adenosyl-L-homocysteine


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Plasmodium falciparum)


name: H2O + salicin-6-phosphate => beta-D-glucose 6-phosphate + salicyl alcohol


name: TRAF6 oligomerizes within the ALPK1:ADP-heptose:TIFA oligomer complex (Homo sapiens)


name: (2S)-2-(furan-3-yl)-2-hydroxyacetonitrile => furan-3-carbaldehyde + hydrogen cyanide


name: 7,8-dihydromethanopterin + AH2 => 5,6,7,8-tetrahydromethanopterin + A


name: (9Z)-octadecenoate + ethanol + H(+) => ethyl (9Z)-octadecenoate + H2O


name: adenosine 2',5'-bisphosphate + H2O => AMP + phosphate


name: carbonyl sulfide + H(+) + hydrogen sulfide => carbon disulfide + H2O


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + lipid IVA (E. coli) <=> a 2-acyl-sn-glycero-3-phosphocholine + lipid IVB (E. coli)


name: RAC1:GTP binds NOX1 complex (Danio rerio)


name: PGR binds PGR agonists (Drosophila melanogaster)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Caenorhabditis elegans)


name: Dimeric TGF-beta-1 binds to the receptor (Canis familiaris)


name: (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O = (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H(+)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADH + O2 = 4beta-hydroxymethyl-4alpha-methylzymosterol + H2O + NAD(+)


name: solute:inorganic anion antiporter activity


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Homo sapiens)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Homo sapiens)


name: Vitronectin binds to C5b-C7 complex (Gallus gallus)


name: estrone 3-sulfate(out) + glutarate(in) <=> estrone 3-sulfate(in) + glutarate(out)


name: 2-methylpropan-1-amine + H2O + NADP(+) => 2-methylpropanal + H(+) + NADPH + NH4(+)


name: rifampicin ortho-naphthoquinone carboxamide <=> rifampicin para-naphthoquinone carboxamide


name: a dicarboxylate(in) + L-erythro-7,8-dihydrobiopterin(out) <=> a dicarboxylate(out) + L-erythro-7,8-dihydrobiopterin(in)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Bos taurus)


name: Active ARF recruits coatomer to the Golgi (Dictyostelium discoideum)


name: IL35 binds IL12RB2:IL12RB2 receptor (Bos taurus)


name: ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate => ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein]


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Homo sapiens)


name: hydroquinone + O2 = (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate + H(+)


name: a ganglioside Ac-O-9-GD3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside Ac-O-9-GD2 + H(+) + UDP


name: 3xPPCDC:3FMN decarboxylates PPC (Canis familiaris)


name: 24,25-dihydrolanosterol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: CSF1 dimer binds CSF1R or IL34 (Homo sapiens)


name: an L-alpha-amino acid + glycocholate = an N-choloyl-L-alpha-amino acid + glycine


name: PLK3 phosphorylates TP53 (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) <=> a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out)


name: hexadecanoyl-CoA + sphinga-(4E,8E)-dienine <=> CoA + H(+) + N-hexadecanoylsphinga-(4E,8E)-dienine


name: Formation of AT-AC C complex (Canis familiaris)


name: UBA1 adenylates ubiquitin in the nucleoplasm (Xenopus tropicalis)


name: ADP + H(+) + oxidized coenzyme alpha-F420-3 + phosphate => ATP + L-glutamate + oxidized coenzyme F420-2


name: biphenyl-2,3-diol + H(+) + NADH => (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: MAF1 translocates to the nucleus (Dictyostelium discoideum)


name: AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it (Sus scrofa)


name: USP9X (FAM) binds to ubiquitinated SMAD4 (Caenorhabditis elegans)


name: CLOCK acetylates lysine-10 of histone H3, H4 (Homo sapiens)


name: NAD(+) + resolvin D1 <=> 17-oxoresolvin D1 + H(+) + NADH


name: 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+) => L-tyrosine + NADPH + S-adenosyl-L-methionine


name: 2,2-dihydroxyspirilloxanthin = 2-oxospirilloxanthin + H2O


name: MITF-M-dependent DCT gene expression (Homo sapiens)


name: H2O2 + pyridine <=> H2O + pyridine N-oxide


name: [aequorin] + 3 Ca(2+) = [aequorin]--dioxetanone


name: RAC1 and CDC42 activate PAK3 (Mus musculus)


name: anisole + H(+) + S-adenosyl-L-homocysteine => phenol + S-adenosyl-L-methionine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of PKC theta (Drosophila melanogaster)


name: ATP + H(+) + L-lysine => diphosphate + L-lysyl-5'-AMP


name: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] => acetyl-CoA + N-terminal L-seryl-[histone H2A]


name: HMGB1 binds LPS (Caenorhabditis elegans)


name: bacterial-type RNA polymerase core enzyme binding


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Canis familiaris)


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Caenorhabditis elegans)


name: NOTCH precursor cleaved to form mature NOTCH (Mus musculus)


name: SARS-CoV-2 N binds to G3BP1,G3BP2 (Homo sapiens)


name: a 1-acyl-2-[(7Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: NADPH + O2 + quinolin-8-ol => 8-hydroxyquinoline N-oxide + H2O + NADP(+)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Gallus gallus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: K63polyUb-IRAK1 dissociates (Drosophila melanogaster)


name: Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE (Bos taurus)


name: Formation of allysine by LOX (Bos taurus)


name: HCFC1 binds SET1A complex (Drosophila melanogaster)


name: L-lysyl-[protein] + lactoyl-CoA = CoA + H(+) + N(6)-lactoyl-L-lysyl-[protein]


name: MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Xenopus tropicalis)


name: (2Z,4E)-2-aminomuconate + H2O <=> (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH4(+)


name: (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+) => 4-hydroxyestrone + O2


name: Digestion of linear starch (amylose) by extracellular amylase (Danio rerio)


name: AMP + ATP <=> ADP + ADP [AK2] (Xenopus tropicalis)


name: (-)-ent-copalol + diphosphate => ent-copalyl diphosphate + H2O


name: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD(+) <=> 6-oxocyclohex-1-ene-1-carbonyl-CoA + H(+) + NADH


name: Pol II elongation complex moves on the template as transcript elongates (Mus musculus)


name: 19 H(+) + holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine <=> 9 CO2 + 9 CoA + dihydromonacolin L-[lovastatin nonaketide synthase] + 6 H2O + 11 NADP(+) + S-adenosyl-L-homocysteine


name: CES1,CES2 hydrolyze ASA- to ST (Dictyostelium discoideum)


name: The receptor:G-protein complex releases GDP (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: H(+) + menaquinone-8 + NADPH => menaquinol-8 + NADP(+)


name: (S)-2-hydroxypropyl-coenzyme M <=> (S)-1,2-epoxypropane + coenzyme M


name: N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine <=> N-acyl-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoate (4E)-octadecasphin-4-enine


name: FLT3LG dimer:FLT3 binds FLT3 (Bos taurus)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Xenopus tropicalis)


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Sus scrofa)


name: ROS,RNS oxidize ACO2:4Fe-4S (Rattus norvegicus)


name: The IFT-A complex recruits TULP3 (Rattus norvegicus)


name: cholest-4-en-3-one + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] => (25R)-3-oxocholest-4-en-26-oate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: ACLY tetramer transforms CIT to Ac-CoA (Drosophila melanogaster)


name: a cardiolipin + CMP + H(+) => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a CDP-1,2-diacyl-sn-glycerol


name: SORD oxidizes D-sorbitol to Fru (Mus musculus)


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Bos taurus)


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Danio rerio)


name: L-lysine + NADP(+) <=> 2 H(+) + L-1-piperideine-6-carboxylate + NADPH + NH4(+)


name: Gi activation by P2Y purinoceptor 12 (Mus musculus)


name: The Kiss receptor GPR54 binds kisspeptin (Mus musculus)


name: (S)-versiconol + NADP(+) = (2S-3S)-versiconal hemiacetal + H(+) + NADPH


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Sus scrofa)


name: (6S)-5,6,7,8-tetrahydrofolate + O2 + sarcosine <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O2


name: REV1 binds AP-dsDNA (Caenorhabditis elegans)


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Saccharomyces cerevisiae)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2 <=> (2S)-3-(4-hydroxyphenyl)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2


name: 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine => 4',7-dihydroxy-3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Homo sapiens)


name: ATP + butanoyl-CoA + hydrogencarbonate <=> (2R)-ethylmalonyl-CoA + ADP + H(+) + phosphate


name: 6,8-dihydroxypurine + H2O + O2 <=> H2O2 + urate


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: Unknown kinase phosphorylates RBV-MP (Homo sapiens)


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Homo sapiens)


name: Beta-defensins bind microbial membranes causing disruption (Bos taurus)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside


name: Autophosphorylation of LTK dimer:ALKAL1,2 (Homo sapiens)


name: NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP (Sus scrofa)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate = a ganglioside GM4 (d18:1(4E)) + CMP + H(+)


name: 2-demethylmenaquinol-8 + H(+) + trimethylamine N-oxide = 2-demethylmenaquinone-8 + H2O + trimethylamine


name: GBF1 recruits ARF:GDP to the Golgi (Schizosaccharomyces pombe)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + octadecanoate


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + polyneuridine aldehyde


name: NADP(+) + sphinganine => 3-oxosphinganine + H(+) + NADPH


name: 5,6-dihydrouracil + NAD(+) => H(+) + NADH + uracil


name: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + GDP + H(+) => (R)-glycerate + GDP-alpha-D-glucose


name: Internalisation of the insulin receptor (Sus scrofa)


name: aclacinomycin T + dTDP + 2 H(+) => aklavinone + dTDP-beta-L-rhodosamine


name: (2S)-2-hydroxy-3,3-dimethylbutanenitrile => 2,2-dimethylpropanal + hydrogen cyanide


name: eNoSC dimethylates histone H3 at lysine-9 (Sus scrofa)


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Xenopus tropicalis)


name: MIA2 and MIA3 load procollagen VII into COPII vesicles (Rattus norvegicus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = diphosphate + fusoxypene B


name: phosphate + sulfoacetaldehyde => acetyl phosphate + H(+) + sulfite


name: [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate => [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Mus musculus)


name: CaMKII binds activated NMDA receptor (Homo sapiens)


name: a 12-hydroxyjasmonyl-L-alpha-amino acid + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => a 12-hydroxy-12-oxojasmonyl-L-alpha-amino acid + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Generation of a DNA double strand break (Gallus gallus)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Mus musculus)


name: SUMO-CRABP2 binds atRA (Canis familiaris)


name: ISGylation of E2 conjugating enzymes (Sus scrofa)


name: (2-aminophenyl)succinate + succinyl-CoA <=> 3-(2-aminophenyl)succinyl-CoA + succinate


name: (2R,3S)-2,4',7-trihydroxyisoflavanone = daidzein + H(+) + H2O


name: CD28 homodimer binds B7-1 homodimer (Canis familiaris)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Saccharomyces cerevisiae)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Bos taurus)


name: 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase]


name: ATP + beta-alanine + histamine = AMP + carcinine + diphosphate + H(+)


name: Fusion of ERC and phagosome (Bos taurus)


name: chloride(in) + oxalate(out) => chloride(out) + oxalate(in)


name: CO2 + glutaryl-CoA + NADH => 2-oxoadipate + CoA + NAD(+)


name: XYLB phosphorylates D-xylulose (Rattus norvegicus)


name: acetyl-CoA + CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate => CMP-5'-(N-acetyl-N-hydroxy-3-aminopropyl)phosphonate + CoA


name: ATP + N-acetyl-D-glucosamine <=> ADP + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate


name: Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol (Homo sapiens)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Dictyostelium discoideum)


name: (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H(+) + NADPH <=> (21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + NADP(+)


name: NRF1, PPRC1:HCFC1:NRF2 bind the TFB1M promoter (Homo sapiens)


name: (2E)-geranyl diphosphate <=> (1S,5S)-sabinene + diphosphate


name: CYP1A2 hydroxylates AFB1 to AFM1 (Sus scrofa)


name: MBTPS1 (S1P) cleaves CREB3 (Homo sapiens)


name: (2E,6E)-farnesyl phosphate + H2O <=> (2E,6E)-farnesol + phosphate


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Mus musculus)


name: RTP1S and RTP2 bind underrepresented Olfactory Receptors (uORs) (Homo sapiens)


name: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil


name: Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements (Canis familiaris)


name: CoA + H(+) + N-terminal N-acetyl-L-(Asp/Glu)3-[protein] => acetyl-CoA + N-terminal L-(Asp/Glu)3-[protein]


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) => diphosphate + thiamine phosphate


name: DUOX1,2 reduce O2 to H2O2 (Xenopus tropicalis)


name: 17beta-estradiol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: Formation of p-STAT1 homodimer (Gallus gallus)


name: a menaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine <=> 5'-deoxyadenosine + an 8-methylmenaquinone + 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L-homocysteine


name: all-trans-retinyl tetradecanoate + CoA => all-trans-retinol + tetradecanoyl-CoA


name: Formation of Cyclin B:Cdc2 complexes (Bos taurus)


name: (S)-isodihydrodehydrodiconiferyl alcohol + NADP(+) => (-)-dehydrodiconiferyl alcohol + H(+) + NADPH


name: 5,10-methylenetetrahydromethanopterin + NADP(+) <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH


name: ALDH1A1 oxidises GA to DGA (Canis familiaris)


name: ATP binding to HSP90 triggers conformation change (Sus scrofa)


name: Dissociation of L13a from the 60s ribosomal subunit (Bos taurus)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Mus musculus)


name: Pellino ubiquitinates IRAK1 (Rattus norvegicus)


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 (Saccharomyces cerevisiae)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Mus musculus)


name: Ubiquitinated Orc1 is degraded by the proteasome (Rattus norvegicus)


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Gallus gallus)


name: MAPK8 phosphorylation (Canis familiaris)


name: GLI1 is degraded by the proteasome after ubiquitination by ITCH (Homo sapiens)


name: 3 a menaquinol(in) + 2 H(+)(out) + nitrite(out) => 3 a menaquinone(in) + 2 H2O(out) + NH4(+)(out)


name: 5,6-dihydrothymine + H2O = 3-(carbamoylamino)-2-methylpropanoate + H(+)


name: (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA = (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H2O


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP => an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose


name: 2 Fe(III)-[cytochrome b5] + H2O + N-acyl-4-hydroxyeicosasphinganine => an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: 2 AH2 + all-trans-adonixanthin + 2 O2 = 2 A + all-trans-(3S,3'S)-astaxanthin + 3 H2O


name: dTMP + H2O + NADP(+) => dUMP + formaldehyde + H(+) + NADPH


name: RAC2 translocates to the phagocytic vesicle membrane (Mus musculus)


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Saccharomyces cerevisiae)


name: Ubiquitinated Cdc6 is degraded by the proteasome (Sus scrofa)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Homo sapiens)


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: calcium-dependent cysteine-type endopeptidase inhibitor activity


name: D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+) => diphosphate + GDP-D-glycero-alpha-D-manno-heptose


name: LTC4 is exported from the cytosol by ABCC1 (Sus scrofa)


name: AKAP8L binds MLL1 complex (Rattus norvegicus)


name: Phosphorylation of STATs (Rattus norvegicus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = (9Z,12Z)-octadecadienoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: H2O + N-hexanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-hexanoyl ethanolamine


name: H2O + O2 + sarcosine = formaldehyde + glycine + H2O2


name: AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)


name: Formation of Cyclin E:Cdk2 complexes (Danio rerio)


name: PARVB interacts with Alpha-actinin (Homo sapiens)


name: N-carbamoylputrescine + NH4(+) => agmatine + H2O


name: Inhibin-A binding to TGFBR3 (Gallus gallus)


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Caenorhabditis elegans)


name: 3,4-dehydrothiomorpholine-3-carboxylate + 2 H(+) + NADPH => (3R)-1,4-thiomorpholine-3-carboxylate + NADP(+)


name: HSF1-mediated gene expression (Homo sapiens)


name: glycyl-L-proline + H2O = glycine + L-proline


name: Fall Back to Closed Pre-initiation Complex (Saccharomyces cerevisiae)


name: (1R,2R)-pseudoephedrine + NAD(+) <=> (R)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: myo-inositol + UDP-alpha-D-galactose <=> alpha-D-galactosyl-(1->3)-1D-myo-inositol + H(+) + UDP


name: H(+) + orotidine 5'-phosphate = CO2 + UMP


name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Sus scrofa)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Dictyostelium discoideum)


name: BPHL hydrolyses VACV to ACV (Sus scrofa)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] => (11R)-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucuronate = cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + H(+) + UDP


name: PCK1 phosphorylates OA to yield PEP (Mus musculus)


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Rattus norvegicus)


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Mus musculus)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Xenopus tropicalis)


name: GMPS dimer transforms 6TXMP to 6TGMP (Sus scrofa)


name: 1,2-didecanoylglycerol + H2O <=> decanoate + decanoylglycerol + H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+)


name: amidinoproclavaminate + CO2 + succinate => 2-oxoglutarate + deoxyamidinoproclavaminate + O2


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-hexacosanoyl-(4R)-hydroxysphinganine + O2 <=> 2 Fe(III)-[cytochrome b5] + H2O + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Rattus norvegicus)


name: adenosine(4) in tRNA(His) + S-adenosyl-L-methionine = 2'-O-methyladenosine(4) in tRNA(His) + H(+) + S-adenosyl-L-homocysteine


name: The p75NTR:NgR:MDGI binds RHOA-GDI (Bos taurus)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Gallus gallus)


name: H2O + N,N'-diacetylchitobiose => acetate + beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine


name: alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin (Sus scrofa)


name: cis,trans-4-hydroxymuconate semialdehyde + H2O + NAD(+) = 2 H(+) + maleylacetate + NADH


name: ATG12 forms a thioester bond with ATG7 dimer (Rattus norvegicus)


name: KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Rattus norvegicus)


name: dihydrocarvone + H(+) + NADH => dihydrocarveol + NAD(+)


name: IFNL2,IFNL3 bind IL10RB:TYK2 and IFNLR1:JAK1 (Canis familiaris)


name: SHC1 phosphorylation by phosphorylated EGFR (Sus scrofa)


name: a pyrimidine ribonucleoside + H2O = a pyrimidine nucleobase + D-ribose


name: Activation of SHP2 through the binding to phospho-Gab1 (Gallus gallus)


name: Formation of PRC2-EZH2 complex (Homo sapiens)


name: beta-alanine + 2 H(+) + NADH => 3-aminopropanal + H2O + NAD(+)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Drosophila melanogaster)


name: Endophilins recruit synaptojanins to the clathrin-coated pit (Bos taurus)


name: SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)


name: chloride + D-tryptophan + FADH2 + O2 <=> 6-chloro-D-tryptophan + FAD + 2 H2O


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Xenopus tropicalis)


name: Activated human JNKs migrate to nucleoplasm (Bos taurus)


name: GDIs block activation of RHOA (Danio rerio)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: SFTPB dimer,C translocate from multivesicle body to lamellar body (Canis familiaris)


name: PGLYRP2 binds bacterial peptidoglycan (Rattus norvegicus)


name: a very-long-chain (3R)-3-hydroxyacyl-CoA <=> a very-long-chain (2E)-enoyl-CoA + H2O


name: 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O => 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA


name: RNF181 binds BCL10 and Ubiquitin:E2 (Canis familiaris)


name: The UDP/CysLT (P2Y17) receptor can bind UTP (Sus scrofa)


name: CO2 + 2 H2O + NADP(+) + violacein => 2 H(+) + NADPH + 2 O2 + protoviolaceinate


name: Activated FGFR3 phosphorylates PLCG1 (Drosophila melanogaster)


name: acetyl-CoA + alpha-D-glucosaminyl-[heparan sulfate](n) => CoA + H(+) + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n)


name: 7,7',9,9'-tetra-cis-lycopene + 2 a quinol => 9,9'-di-cis-zeta-carotene + 2 a quinone


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Mus musculus)


name: cis-homoaconitate + H2O => (2R,3S)-homoisocitrate


name: USP7 deubiquitinates monoubiquitinated PTEN (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphate + choline + H(+)


name: Bitter compound binds bitter taste receptor (TAS2R) (Rattus norvegicus)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Homo sapiens)


name: RANKL,sRANKL trimer binds RANK (Sus scrofa)


name: 2-oxoglutarate + CoA + NAD(+) <=> CO2 + NADH + succinyl-CoA


name: Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol (Homo sapiens)


name: eicosan-1-ol + hexadecanoyl-CoA <=> CoA + eicosanyl hexadecanoate


name: dodecanedioyl-CoA + H2O => CoA + dodecanedioate + H(+)


name: H(+) + nectriapyrone + S-adenosyl-L-homocysteine => desmethylnectriapyrone + S-adenosyl-L-methionine


name: The receptor is activated (Gallus gallus)


name: Cholecystokinin receptors bind cholecystokinin (Gallus gallus)


name: a 1-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O => 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Canis familiaris)


name: ER calcium channels open in response to activated PKA (Dictyostelium discoideum)


name: Phosphorylated MAPKs phosphorylate ATF-2 (Drosophila melanogaster)


name: adenosine + H2O + 2 O2 <=> 9-riburonosyladenine + H(+) + 2 H2O2


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Gallus gallus)


name: (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate


name: SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Sus scrofa)


name: 2 L-dopa + O2 => 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+)


name: RPE dimers isomerise RU5P to XY5P (Schizosaccharomyces pombe)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:dsDNA:ZBP1:TBK1 (Homo sapiens)


name: NRXNs bind CASK:Protein 4.1 (Rattus norvegicus)


name: Activation of ATP sensitive Potassium channels in muscle cells (Mus musculus)


name: Formation of Malonyl-CoA from Acetyl-CoA (liver) (Xenopus tropicalis)


name: H(+) + L-arogenate <=> CO2 + H2O + L-phenylalanine


name: glycine + oxaloacetate = glyoxylate + L-aspartate


name: 32-hydroxy-24,25-dihydrolanosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 24,25-dihydrolanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: (2E)-geranyl diphosphate <=> (1S,5S)-alpha-pinene + diphosphate


name: RAB43:GTP binds USP8NL (Caenorhabditis elegans)


name: KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Gallus gallus)


name: 1-O-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA => a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: SEMA6D binds to PLXNA1:TREM2:DAP12 (Rattus norvegicus)


name: Transcriptional activation of CDKN1A by TP53 is inhibited by EP400 (Homo sapiens)


name: Cytoslic carboxylases translocate to mitochondrial matrix (Dictyostelium discoideum)


name: 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Saccharomyces cerevisiae)


name: benzylthiol + O2 = benzothialdehyde + H2O2


name: H2O + N-(acetyl)-sphing-4-enine <=> acetate + sphing-4-enine


name: CLN3 transports GalCer to plasma membrane (Xenopus tropicalis)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Bos taurus)


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Xenopus tropicalis)


name: CO2 + phenol => 4-hydroxybenzoate + H(+)


name: Activated FGFR3 phosphorylates FRS2 (Bos taurus)


name: Collagen type XII degradation by MMP12 (Homo sapiens)


name: Transport of Antigen peptide in to ER (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: H2O + N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein] => N(6)-(D-erythrulosyl)-L-lysyl-[protein] + phosphate


name: 2 Na(+)(out) + nitrate(out) = 2 Na(+)(in) + nitrate(in)


name: KIBRA (WWC1) binds LATS proteins (Rattus norvegicus)


name: (E)-ferulate + ATP + H(+) => (E)-feruloyl-AMP + diphosphate


name: H(+) + NADPH + 2 phytyl diphosphate <=> (14E,18E)-lycopadiene + 2 diphosphate + NADP(+)


name: putrescine + S-adenosyl 3-(methylsulfanyl)propylamine <=> H(+) + S-methyl-5'-thioadenosine + spermidine


name: 2-acyl LPC is acylated to PC by LPCAT (Homo sapiens)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Schizosaccharomyces pombe)


name: (2E,4Z)-4-hydroxy-6-oxohexa-2,4-dienoate + H(+) => hydroquinone + O2


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Sus scrofa)


name: Galpha-olf:GTP binds to adenylate cyclase and activates it (Danio rerio)


name: intermediate-density lipoprotein particle binding


name: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)


name: MAP2K1 phosphorylates MAPK3 (Danio rerio)


name: (tRNA)-3'-end (ribonucleoside 5'-phosphate)-(guanosyl 5'-phosphate)-(cytosyl 5'-phosphate)-(cytosyl 5'-phosphate)-(adenosine 5'-phosphate) + H2O = GpCpCpA + H(+) + tRNA 3'-end (ribonucleotide 3'-phosphate)


name: GPIHBP1 binds HSPG:LPL dimer (Bos taurus)


name: 5,6-dihydrouridine(20a) in tRNA + NADP(+) <=> H(+) + NADPH + uridine(20a) in tRNA


name: USP10 deubiquitinates SNX3, CFTR (Schizosaccharomyces pombe)


name: beta-D-Gal-(1<->1')-Cer + CMP-N-acetyl-beta-neuraminate => CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide


name: DCAKD phosphorylates DP-CoA (Plasmodium falciparum)


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Homo sapiens)


name: dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Rattus norvegicus)


name: CO2 + formaldehyde + L-lysyl-[protein] + succinate => 2-oxoglutarate + N(6)-methyl-L-lysyl-[protein] + O2


name: NEK9 binds NEK6/NEK7 in the cytosol (Homo sapiens)


name: N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: 10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate


name: MTRR reduces cob(II)alamin to meCbl (Canis familiaris)


name: H(+)(in) + L-alanine(out) + Na(+)(out) = H(+)(out) + L-alanine(in) + Na(+)(in)


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Bos taurus)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Rattus norvegicus)


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Canis familiaris)


name: 2'-deoxyinosine(in) + H(+)(in) <=> 2'-deoxyinosine(out) + H(+)(out)


name: a 2-acylglycerol + a carboxylate + H(+) => a 1,2-diacylglycerol + H2O


name: 5alpha-cholest-8-en-3-one + H(+) + NADPH => 5alpha-cholest-8-en-3beta-ol + NADP(+)


name: PKN1 stimulates association of AR with NCOA2 (Drosophila melanogaster)


name: CK1 phosphorylates p-GLI3 (Rattus norvegicus)


name: deoxycholoyl-CoA + NAD(+) <=> 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + H(+) + NADH


name: Dissociation of CaM and CAMK2 autophosphorylation (Sus scrofa)


name: NEU3 cleaves GM3 to form LacCer (plasma membrane) (Danio rerio)


name: a ganglioside GT1a + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1b + CMP + H(+)


name: 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate


name: Abortive Initiation After Second Transition (Drosophila melanogaster)


name: Release of platelet secretory granule components (Drosophila melanogaster)


name: ARSC hydrolyzes steroid sulfates (Rattus norvegicus)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Bos taurus)


name: choloyl-CoA + H2O => cholate + CoA + H(+)


name: an archaeal dolichyl N-acetyl-alpha-D-glucosaminyl phosphate + UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate <=> an archaeal dolichyl 3-O-(2,3-diacetamido-2,3-dideoxy- beta-D-glucuronosyl)-N-acetyl- alpha-D-glucosaminyl phosphate + H(+) + UDP


name: Formation of FACT complex (Canis familiaris)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Saccharomyces cerevisiae)


name: ACAD11 dehydrogenates BH-CoA (Canis familiaris)


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Homo sapiens)


name: 20-hydroxy prostaglandin A1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + prostaglandin A1 + reduced [NADPH--hemoprotein reductase]


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Homo sapiens)


name: ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Homo sapiens)


name: Phosphorylation and activation of VAV (Rattus norvegicus)


name: Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Rattus norvegicus)


name: PTGIS, CYP8A1 isomerise PGH2 to PGI2 (Xenopus tropicalis)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Homo sapiens)


name: H2O + N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine = 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)


name: Recruitment of VAV to p-SLP-76 (Xenopus tropicalis)


name: L-asparagine(out) + L-glutamine(in) + Na(+)(out) => L-asparagine(in) + L-glutamine(out) + Na(+)(in)


name: Phosphorylated Cdc6 is exported from the nucleus (Gallus gallus)


name: 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA => 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA


name: menadiol + 2 O2 = 2 H(+) + menadione + 2 superoxide


name: 19-oxo-androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] => estrone + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + GDP-alpha-D-perosamine = GDP-4-dehydro-alpha-D-rhamnose + L-glutamate


name: PGLYRP3,4 binds bacterial peptidoglycan (Xenopus tropicalis)


name: H(+)(in) + uridine(in) = H(+)(out) + uridine(out)


name: (4Z)-2-oxohept-4-enedioate + CO2 => (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+)


name: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H2O


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Bos taurus)


name: 5-valerolactone + H2O + NADP(+) => cyclopentanone + H(+) + NADPH + O2


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: alpha-maltoheptaose + phosphate => alpha-D-glucose 1-phosphate + alpha-maltohexaose


name: USP8 deubiquitinates STAM2:HGS (Sus scrofa)


name: XYLB phosphorylates D-xylulose (Schizosaccharomyces pombe)


name: H(+)(out) + tetracycline(in) <=> H(+)(in) + tetracycline(out)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphate


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Caenorhabditis elegans)


name: ASIC3 channel blockers bind ASIC3 trimer (Xenopus tropicalis)


name: futalosine + H2O = dehypoxanthine futalosine + hypoxanthine


name: chlorophyllide a + H(+) + H2O <=> 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + CO2 + methanol


name: beta-D-fructose 6-phosphate + GDP-alpha-D-mannose <=> beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Caenorhabditis elegans)


name: apo-UQCRFS1 binds LYRM7 (Rattus norvegicus)


name: 4-hydroxy-6-(14-hydroxytetradecyl)-pyran-2-one + 2 CO2 + 3 CoA => 15-hydroxypentadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: USP21 deubiquitinates RIPK1,DDX58 (Caenorhabditis elegans)


name: p-PKR dimer phosphorylates PTPN2 (Danio rerio)


name: 1-(2-aminophenyl)decane-1,3-dione + CO2 + L-cysteinyl-[PqsC protein] => (2-aminobenzoyl)acetate + H(+) + S-octanoyl-L-cysteinyl-[PqsC protein]


name: DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Bos taurus)


name: 3'-dephospho-CoA(in) + AMP(out) <=> 3'-dephospho-CoA(out) + AMP(in)


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Dictyostelium discoideum)


name: CUL3:RBX1 ubiquitinates KEAP1 (Drosophila melanogaster)


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Caenorhabditis elegans)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Xenopus tropicalis)


name: HAS1,2,3 mediate the polymerization of HA (Canis familiaris)


name: an L-alpha-amino acid + cholate <=> an N-choloyl-L-alpha-amino acid + H2O


name: CTP + 2 H2O <=> CMP + 2 H(+) + 2 phosphate


name: Dimerization of LIMK1 by Hsp90 (Mus musculus)


name: Interleukin-3 receptor alpha subunit binds Interleukin-3 (Bos taurus)


name: [phosphate](n+1) + n H2O => n H(+) + (n+1) phosphate


name: HSP90AA1 binds p-6Y-VEGFR2 (Gallus gallus)


name: H(+) + L-valine => 2-methylpropan-1-amine + CO2


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-jasmololone = CoA + jasmolin II


name: ATP + butanoate + H(+) + NADPH => AMP + butanal + diphosphate + NADP(+)


name: (2E,6E)-farnesyl diphosphate + H2O => (3S,6E)-nerolidol + diphosphate


name: hydroxymethylbilane + 4 NH4(+) => H2O + 4 porphobilinogen


name: CHSY1 transfers GalNAc to chondroitin (Xenopus tropicalis)


name: 12-methyltridecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(13-methyl-2-oxotetradecyl)pyran-2-one + 3 CO2 + 4 CoA


name: SORD tetramer oxidizes xylitol to D-xylulose (Caenorhabditis elegans)


name: "phenylalanine aminomutase (D-beta-phenylalanine forming)"


name: a fatty acid + an aliphatic alcohol + H(+) => a fatty acid ester + H2O


name: NSF and SNAPs bind the cis-SNARE at the Golgi (Caenorhabditis elegans)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Canis familiaris)


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Gallus gallus)


name: L-leucine(out) + S-methylmercury-L-cysteine(in) => L-leucine(in) + S-methylmercury-L-cysteine(out)


name: a 3'-end 2'-deoxyribonucleotide-3'-(L-tyrosyl phosphate)-DNA + H2O = a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H(+) + L-tyrosine


name: 1,3-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-glycerol <=> 1,2,3-tri-(9Z-octadecenoyl)-glycerol + glycerol


name: The SRP receptor binds the SRP:nascent peptide:ribosome complex (Homo sapiens)


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Rattus norvegicus)


name: Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Gallus gallus)


name: 8-demethyltetracenomycin C + H2O + 2 NADP(+) => 2 H(+) + 2 NADPH + 2 O2 + tetracenomycin B2


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Drosophila melanogaster)


name: a 2-oxocarboxylate + L-alanine <=> an L-alpha-amino acid + pyruvate


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Sus scrofa)


name: 12,13-epoxy-(9Z)-octadecenoate + H2O => 12,13-dihydroxy-(9Z)-octadecenoate


name: NAD(+) + propanoyl-CoA = acryloyl-CoA + H(+) + NADH


name: GLUT1 tetramer binds 4xATP (Saccharomyces cerevisiae)


name: SIRT1 deacetylates HINT1 dimer (Canis familiaris)


name: 2,4-dichlorophenol + CO2 + pyruvate + succinate => (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2


name: 6-aminohexanoate + [N-(6-aminohexanoyl)](n-1) => [N-(6-aminohexanoyl)](n) + H2O


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Mus musculus)


name: Aquaporin-4 passively transports water out of cell (Plasmodium falciparum)


name: The keratan chain can be capped by N-acetylneuraminic acid (Mus musculus)


name: CFTR binds components of the ERAD machinery for ubiquitination and degradation (Homo sapiens)


name: (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + O2 = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O2


name: 4-nitrophenyl sulfate + adenosine 3',5'-bisphosphate => 3'-phosphoadenylyl sulfate + 4-nitrophenol


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Gallus gallus)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Mus musculus)


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycerol + H(+)


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Rattus norvegicus)


name: 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: Association of procollagen type VIII (Drosophila melanogaster)


name: beta-ureidopropionate + H2O => beta-alanine + NH4+ + CO2 (Canis familiaris)


name: diphosphate + UDP-alpha-D-glucuronate => 1-phospho-alpha-D-glucuronate + H(+) + UTP


name: an omega-hydroxy fatty acid + O2 + reduced [NADPH--hemoprotein reductase] => an omega-oxo fatty acid + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Orexin 2 receptor can bind orexin-B neuropeptide (Danio rerio)


name: (2E)-geranyl diphosphate + flaviolin => 3-linalylflaviolin + diphosphate


name: RHOJ GAPs stimulate RHOJ GTPase activity (Sus scrofa)


name: ATP + O-alkylglycerone <=> 1-O-alkylglycerone 3-phosphate + ADP + H(+)


name: Phosphorylation of YAP by LATS2 (Sus scrofa)


name: RNA Polymerase II Promoter Opening: First Transition (Drosophila melanogaster)


name: ergothioneine(out) + Na(+)(out) <=> ergothioneine(in) + Na(+)(in)


name: H2O + N-decanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-decanoyl ethanolamine


name: Activation of Calcineurin (Homo sapiens)


name: glycine + glyoxylate => (3R)-3-hydroxy-L-aspartate


name: H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(966) in 16S rRNA + S-adenosyl-L-methionine


name: "Rhizobium leguminosarum exopolysaccharide glucosyl ketal-pyruvate-transferase"


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine => 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: Interaction and oligomerization of MALT1 to Bcl10 (Sus scrofa)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Sus scrofa)


name: CoA-glutathione + H(+) + NADPH => CoA + glutathione + NADP(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine <=> a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + H(+) + S-adenosyl-L-homocysteine


name: Recruitment of elongation factors to form elongation complex (Drosophila melanogaster)


name: indole-3-pyruvate + S-adenosyl-L-methionine => (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + S-adenosyl-L-homocysteine


name: (+)-dehydrodiconiferyl acid ketone + a quinone + H2O <=> (+)-dehydrodiconiferyl acid carboxylate + a quinol + H(+)


name: BIL dissociates from GSTA1, FABP1 (Dictyostelium discoideum)


name: (1R,2R,3R)-prephytoene diphosphate + H(+) + NADPH = all-trans-lycopaoctaene + diphosphate + NADP(+)


name: p75NTR:NgR complex interacts with the axonal inhibitor LINGO1 (Homo sapiens)


name: branched-chain amino acid:sodium symporter activity


name: ATP + dodecanoate(out) + H2O <=> ADP + dodecanoate(in) + H(+) + phosphate


name: SFN dimer binds CDK1 and CCNB1 (Xenopus tropicalis)


name: Autoproteolytic cleavage of Hh precursors (Mus musculus)


name: deamido-NAD(+) + diphosphate => ATP + H(+) + nicotinate beta-D-ribonucleotide


name: L-dihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: 3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O


name: Caspase mediated cleavage of alpha-II-Fodrin (Canis familiaris)


name: MERTK receptor binds ligands (Gas6 or Protein S) (Mus musculus)


name: delphinidin 3,3',5-tri-O-beta-D-glucoside + H(+) + UDP => delphinidin 3,5-bis-O-beta-D-glucoside + UDP-alpha-D-glucose


name: 3 H(+) + hexadecanoyl-CoA + 3 malonyl-CoA = 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H(+) => (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Rattus norvegicus)


name: Integrin alphaXbeta2 binds JAM3 (Bos taurus)


name: Arachidonic acid is hydroxylated to 19-HETE by CYP(2) (Rattus norvegicus)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Homo sapiens)


name: PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1 (Homo sapiens)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Caenorhabditis elegans)


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Drosophila melanogaster)


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Drosophila melanogaster)