name: OCT2 mediates tubular uptake of organic cations in the kidney (Xenopus tropicalis)


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Bos taurus)


name: H(+) + methanol + N-(1H-1,3-benzodiazol-2-yl)carbamate => carbendazim + H2O


name: (-)-astellatene + diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: ornithine => putrescine + CO2 (Sus scrofa)


name: (+)-dehydrodiconiferyl acid + a quinone = (+)-dehydrodiconiferyl acid ketone + a quinol


name: β1,2-agonists bind ADRB1,2 (Homo sapiens)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Schizosaccharomyces pombe)


name: 5-deoxy-alpha-D-ribose 1-phosphate + adenine => 5'-deoxyadenosine + phosphate


name: Activated FGFR2 binds FRS3 (Rattus norvegicus)


name: Binding of TFIIIC to Type 2 promoter (Schizosaccharomyces pombe)


name: D-mannonate <=> 2-dehydro-3-deoxy-D-gluconate + H2O


name: 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + L-alanine => [5-(aminomethyl)-3-furyl]methyl phosphate + pyruvate


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-acyl-1-deoxysphinganine + O2 => 2 Fe(III)-[cytochrome b5] + 2 H2O + N-acyl-1-deoxysphing-14Z-enine


name: NAD(+) + spermidine <=> dehydrospermidine + H(+) + NADH


name: jasmonate + S-adenosyl-L-methionine => methyl (-)-jasmonate + S-adenosyl-L-homocysteine


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Mus musculus)


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Canis familiaris)


name: L-glutamate(in) + orotate(out) => L-glutamate(out) + orotate(in)


name: H2O + methyl acetate = acetate + H(+) + methanol


name: (7Z,10Z,13Z)-hexadecatrienoyl-CoA + phytol = (7Z,10Z,13Z)-hexadecatrienoate phytyl ester + CoA


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Canis familiaris)


name: p-STAT5 binds CISH, SOCS1 and SOCS2 gene (Homo sapiens)


name: glycolate + NADP(+) <=> glyoxylate + H(+) + NADPH


name: glyoxylate + tetradecamide => N-tetradecanoyl-(2S)-hydroxyglycine


name: butanal + hydrogen cyanide <=> (2S)-2-hydroxypentanenitrile


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Caenorhabditis elegans)


name: an acyl-CoA + sn-glycerol 3-phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine + CoA


name: USP13 and OTUD3 deubiquitinate PTEN (Xenopus tropicalis)


name: CoA + phenylacetyl-AMP <=> AMP + H(+) + phenylacetyl-CoA


name: H2O + N(6)-acetyl-L-lysyl-[alpha-tubulin] <=> acetate + L-lysyl-[alpha-tubulin]


name: 2-oxoglutarate + L-cysteine = 2-oxo-3-sulfanylpropanoate + L-glutamate


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Xenopus tropicalis)


name: ATP + eicosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] => AMP + diphosphate + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: IRE1 dimer autophosphorylates (Bos taurus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Drosophila melanogaster)


name: BTK in PIP3:BTK:G beta-gamma complex is activated (Drosophila melanogaster)


name: Defective SLC35A2 does not exchange UDP-Gal, UDP-GalNAc for UMP (Homo sapiens)


name: Active NIK phosphorylates IKKA dimer (Bos taurus)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphate + H(+) + NADPH = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphate + NADP(+)


name: (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + O2 + reduced [NADPH--hemoprotein reductase] = 5-dehydro-6-demethoxyfumagillol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PDPK1 binds PIP3 (Schizosaccharomyces pombe)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a monoacyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Mus musculus)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Bos taurus)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Bos taurus)


name: a hydroperoxy polyunsaturated fatty acid + H(+) + NADPH <=> a hydroxy polyunsaturated fatty acid + H2O + NADP(+)


name: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine = 3,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine


name: pre-VLDL translocates from RER membrane to SER lumen (Sus scrofa)


name: 3-phenyllactate + NAD(+) = 3-phenylpyruvate + H(+) + NADH


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Rattus norvegicus)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Sus scrofa)


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Sus scrofa)


name: 2-hydroxy-5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 3 H2O + 2 NADP(+) => acetyl-CoA + 6 H(+) + 5 malonyl-CoA + 2 NADPH


name: ATP + CoA + marinolate C => AMP + diphosphate + marinoloyl-CoA C


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Canis familiaris)


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Rattus norvegicus)


name: erythromycin D + S-adenosyl-L-methionine = erythromycin B + H(+) + S-adenosyl-L-homocysteine


name: PIP3 dephosphorylated to PIP2 by DPTEN (Drosophila melanogaster)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Mus musculus)


name: p-Y420-FYN is phosphorylated on S21 (Canis familiaris)


name: a fatty acid + L-tyrosine => an N-(fatty acyl)-L-tyrosine + H2O


name: citrate(out) + 2 Na(+)(out) <=> citrate(in) + 2 Na(+)(in)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Mus musculus)


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Schizosaccharomyces pombe)


name: AFG3L2 degrades mitochondrial matrix proteins (Saccharomyces cerevisiae)


name: Formation of Okazaki fragments (Canis familiaris)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Mus musculus)


name: 2 L-cysteine <=> L-alanine + S-sulfanyl-L-cysteine


name: an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-N-acetyl-alpha-D-galactosamine => an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H(+) + UDP


name: Phosphorylated LEPR Binds STAT5 (Homo sapiens)


name: PKR inhibitors bind PKR (Caenorhabditis elegans)


name: DAXX binds Ub-MDM2 and USP7 (Canis familiaris)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Canis familiaris)


name: an (11E)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: type IV site-specific deoxyribonuclease activity


name: deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Danio rerio)


name: ATP(in) + CoA(in) + H(+)(out) + hexadecanoate(out) = AMP(in) + diphosphate(in) + H(+)(in) + hexadecanoyl-CoA(in)


name: (R)-benzodiazepinedione + dimethylallyl diphosphate = (2S,3R,11R)-aszonalenin + diphosphate


name: RELN:VLDLR:DAB1 binds SH3KBP1 (Bos taurus)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Mus musculus)


name: H2O + oroxylin A 7-O-beta-D-glucuronate => D-glucuronate + H(+) + oroxylin A


name: Translocation of NFATC1:CaN:CaM to nucleus (Mus musculus)


name: Defective GNE does not hydrolyse UDP-GlcNAc (Homo sapiens)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Schizosaccharomyces pombe)


name: isopyridoxal + NAD(+) = 5-pyridoxolactone + H(+) + NADH


name: CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 (Homo sapiens)


name: IL17RD binds p-2S MAP2Ks and MAPKs (Bos taurus)


name: SARS-CoV-2 M protein binds MAP1LC3B (Homo sapiens)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Bos taurus)


name: ADP + H(+) + 4 Na(+)(out) + phosphate => ATP + H2O + 4 Na(+)(in)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: (R)-lactate(in) + H(+)(in) <=> (R)-lactate(out) + H(+)(out)


name: 3-dehydro-scyllo-inosose + H2O => 5-dehydro-L-gluconate + H(+)


name: n fibrin monomers -> fibrin multimer (Homo sapiens)


name: (9Z)-tetradecenoyl-CoA + H2O => adenosine 3',5'-bisphosphate + 2 H(+) + S-(9Z-tetradecenoyl)-4'-phosphopantetheine


name: an omega-methyl fatty acid + O2 + reduced [NADPH--hemoprotein reductase] <=> an omega-hydroxy fatty acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (E)-caffeoyl-CoA + D-threo-isocitrate <=> 2-[(E)-caffeoyl]-D-threo-isocitrate(3-) + CoA


name: HCCS inserts heme into cytochrome c (Canis familiaris)


name: ADP + H(+) + indoxyl sulfate(out) + phosphate => ATP + H2O + indoxyl sulfate(in)


name: acetyl-CoA + an N-hydroxyarylamine => an N-acetoxyarylamine + CoA


name: Intermediate 1 binds HP subcomplex to form Intermediate 2 (Drosophila melanogaster)


name: Formation of the Spliceosomal C* complex (Bos taurus)


name: 1-hexadecanoylglycerone 3-phosphate + octadecan-1-ol <=> 1-O-octadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Sus scrofa)


name: AMP + L-seryl-[peptidyl-carrier protein] => holo-[peptidyl-carrier protein] + L-seryl-5'-AMP


name: Autocatalytic activation of proMMP13 (Bos taurus)


name: L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine <=> H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine


name: Vamp8 associated secretory vesicle to plasma membrane transport (Caenorhabditis elegans)


name: TRAF2:cIAP1/2 complex binds FN14:TWEAK (Sus scrofa)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate => 2-(9Z-octadecenoyl)-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Xenopus tropicalis)


name: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH


name: H(+)(out) + L-arabinose(out) => H(+)(in) + L-arabinose(in)


name: S-adenosyl-L-methionine + uridine(341) in tmRNA = 5-methyluridine(341) in tmRNA + H(+) + S-adenosyl-L-homocysteine


name: Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Dictyostelium discoideum)


name: (4S)-limonene + H(+) + NADPH + O2 = H2O + limonene 1,2-epoxide + NADP(+)


name: 4-prenylphlormethylbutanophenone + diphosphate => 2-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one + dimethylallyl diphosphate


name: chloroacetate + H2O = chloride + glycolate + H(+)


name: a 2'-deoxycytidine in single-stranded DNA + CO2 + glyoxal + succinate => 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + H2O + O2


name: 4-methylumbelliferone sulfate + phenol = 4-methylumbelliferone + phenyl sulfate


name: Fibrillin C-terminal processing (Bos taurus)


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Gallus gallus)


name: Proinsulin translocates from the endoplasmic reticulum to the Golgi (Danio rerio)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA = 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: 2,4-dinitrophenol + H(+) + methanol => 2,4-dinitroanisole + H2O


name: PDGF binds to extracellular matrix proteins (Canis familiaris)


name: TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Canis familiaris)


name: hydrogen sulfide + NAD(+) => NADH + sulfur


name: (4-coumaroyl)acetyl-CoA + CO2 + CoA => 4-coumaroyl-CoA + H(+) + malonyl-CoA


name: 2-oxoglutarate + acetyl-CoA + H2O => (2R)-homocitrate + CoA + H(+)


name: PhosphoChREBP (Thr 653) is exported to cytosol (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester <=> adenosine 3',5'-bisphosphate + H(+) + L-tyrosine methyl ester 4-sulfate


name: Activated calmodulin dissociates from CaMKII-gamma (Homo sapiens)


name: O2 + parthenolide + reduced [NADPH--hemoprotein reductase] <=> 3beta-hydroxyparthenolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CHEK1 phosphorylates TP53 (Homo sapiens)


name: an L-N,N-dihydroxypolyhomomethionine + H(+) <=> an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + H2O


name: (2E,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Gallus gallus)


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Danio rerio)


name: PDCL releases folded G-beta from TRiC/CCT (Rattus norvegicus)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Schizosaccharomyces pombe)


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Orc1 is phosphorylated by cyclin A/CDK2 (Sus scrofa)


name: a dolichyl hexadecanoate + CoA => di-trans,poly-cis-dolichol + hexadecanoyl-CoA


name: Cytosolic DUSPs dephosphorylate MAPKs (Mus musculus)


name: diphosphate + neoverrucosan-5beta-ol => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Rattus norvegicus)


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr) => 2 L-tyrosyl-tRNA(Tyr)


name: (S)-2,3-epoxysqualene + H2O => dammarenediol-II


name: IL37(?-218) binds p-S423,S425-SMAD3 (Homo sapiens)


name: adenosine 3',5'-bisphosphate + H(+) + omega-sulfo-beta-dihydromenaquinone-9 => 3'-phosphoadenylyl sulfate + omega-hydroxy-beta-dihydromenaquinone-9


name: an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + H2O = 3-methylcytosine + a 2'-deoxyribose 5'-phosphate in double-stranded DNA + H(+)


name: a (2S,3R)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH


name: acetoacetyl-CoA + H2O = acetoacetate + CoA + H(+)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Gallus gallus)


name: acetyl-CoA + S-(2-aminoethyl)-L-cysteine => CoA + H(+) + S-(2-acetamidoethyl)-L-cysteine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Drosophila melanogaster)


name: Chromokinesins form dimers (Rattus norvegicus)


name: [thioredoxin]-dithiol + tert-butyl hydroperoxide <=> [thioredoxin]-disulfide + H2O + tert-butanol


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Canis familiaris)


name: a fatty aldehyde + CO2 + H2O => a (2R)-2-hydroperoxy fatty acid + H(+)


name: C20 sphinganine 1-phosphate + H2O <=> C20 sphinganine + phosphate


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Mus musculus)


name: DLST transfers succinyl to CoA (Sus scrofa)


name: LIMK phosphorylates CFL1, inactivating it (Homo sapiens)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: 17-(4-hydroxyphenyl)heptadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] => 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: PLK1 hyperphosphorylates Condensin II complex (Sus scrofa)


name: a  beta-D-glucosyll-(1<->1')-sphingoid base + a fatty acid => beta-D-glucosylceramide + H2O


name: H2O + sn-glycero-3-phospho-1D-myo-inositol <=> H(+) + myo-inositol + sn-glycerol 3-phosphate


name: 2-oxoglutarate + putrescine = 1-pyrroline + H2O + L-glutamate


name: RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Rattus norvegicus)


name: Initial activation of proMMP7 by trypsin (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)


name: Receptor FFAR2 binds carboxylates (Mus musculus)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Sus scrofa)


name: (2E)-geranyl diphosphate <=> beta-thujene + diphosphate


name: POLI incorporates dNMP opposite to damaged DNA base (Xenopus tropicalis)


name: (3R)-hydroxyhexadecanoyl-CoA + NAD(+) => 3-oxohexadecanoyl-CoA + H(+) + NADH


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Drosophila melanogaster)


name: (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CO2 + 2 CoA + H2O + 2 NADP(+) + S-adenosyl-L-homocysteine => 3 H(+) + holo-[2-methylbutanoate polyketide synthase] + 2 malonyl-CoA + 2 NADPH + S-adenosyl-L-methionine


name: GDP-alpha-D-mannose + N-tetracosanoylsphinganine-(1D-myo-inositol) => GDP + H(+) + mannosyl-alpha-1->6-inositol phospho-N-tetracosanoylsphinganine


name: RAP1A exchanges GDP for GTP (Xenopus tropicalis)


name: oxalate + oxidized 2[4Fe-4S]-[ferredoxin] <=> 2 CO2 + reduced 2[4Fe-4S]-[ferredoxin]


name: PHF8 demethylates histone H4K20me1 (Bos taurus)


name: MECP2 binds MOBP gene promoter (Homo sapiens)


name: Two DITs combine to form thyroxine (Drosophila melanogaster)


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Bos taurus)


name: Inactivation of Lck by Csk (Mus musculus)


name: CREBBP binds FOXO1 (Drosophila melanogaster)


name: CDH11 associates with catenins (Gallus gallus)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Bos taurus)


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Xenopus tropicalis)


name: EPH receptors autophosphorylate (Bos taurus)


name: L-PRX:DRP2 binds dystroglycan and laminin-211 (Homo sapiens)


name: ME1 tetramer decarboxylates MAL to PYR (Canis familiaris)


name: Vamp2 associated secretory vesicle to plasma membrane transport (Mus musculus)


name: 3-oxohexadecanoyl-CoA + CO2 + CoA => H(+) + malonyl-CoA + tetradecanoyl-CoA


name: CoA + H(+) + N-octadecanoyl-serotonin => octadecanoyl-CoA + serotonin


name: GOT2 transaminates OA and L-Glu (Bos taurus)


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + pentalenene


name: HSD17B3-like proteins reducde ANDST to TEST (Rattus norvegicus)


name: 5beta-dihydrotestosterone + NADP(+) => H(+) + NADPH + testosterone


name: RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Bos taurus)


name: Formation of the PINCH-ILK-parvin complex (Rattus norvegicus)


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Drosophila melanogaster)


name: KAMKMT transfers 3xCH3 groups from 3xAdoMet to CALM1 (Mus musculus)


name: L-selenocysteine + S-methyl-L-methionine = H(+) + L-methionine + Se-methyl-L-selenocysteine


name: a 2-acyl-sn-glycerol 3-phosphate + H(+) + L-serine => a 2-acyl-sn-glycero-3-phospho-L-serine + H2O


name: 9-riburonosylhypoxanthine + H(+) + H2O => inosine + O2


name: acetyl-CoA + propanoate <=> acetate + propanoyl-CoA


name: DCXR tetramer reduces L-xylulose to xylitol (Mus musculus)


name: misfolded CFTR is degraded by the 26S proteasome (Drosophila melanogaster)


name: acetyl-CoA + N-terminal L-seryl-[ribosomal protein bL12] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[ribosomal protein bL12]


name: NT5C2 tetramer dephosphorylates RBV-MP (Caenorhabditis elegans)


name: (E)-beta-farnesene + diphosphate => (2E,6E)-farnesyl diphosphate


name: NADP(+) + pentan-2-one => (E)-pent-3-en-2-one + H(+) + NADPH


name: CD320-mediated TCN2:RCbl uptake and delivery to lysosome (Sus scrofa)


name: p-VAV family:PIP3 binds RAC1:GDP (Rattus norvegicus)


name: DPP4 binds DPP4 inhibitors (Gallus gallus)


name: CTSG cleaves CASP1(1-404) (Xenopus tropicalis)


name: Budding of connexon-containing transport vesicles from the Golgi (Danio rerio)


name: Parkin transfers Ub to misfolded proteins (Gallus gallus)


name: S-adenosyl-L-methionine + uridine(1939) in 23S rRNA => 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Monoubiquitination of N-myristoyl GAG polyprotein (Homo sapiens)


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Homo sapiens)


name: anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine => 2 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Rattus norvegicus)


name: Deacetylation of cleaved cohesin (Mus musculus)


name: Dissociation of the TP:G13 complex (Homo sapiens)


name: ATP + validone <=> ADP + H(+) + validone 7-phosphate


name: dIMP + H2O = 2'-deoxyinosine + phosphate


name: N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + O2 + reduced [NADPH--hemoprotein reductase] => 2-oxo-N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: butanal + 2 Fe(II)-[cytochrome c] + 2 H(+) => butan-1-ol + 2 Fe(III)-[cytochrome c]


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Homo sapiens)


name: erythromycin C + S-adenosyl-L-methionine => erythromycin A + H(+) + S-adenosyl-L-homocysteine


name: DAG stimulates protein kinase C-delta (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: 1,7-dimethylxanthine + H(+) + NADPH + O2 => 7-methylxanthine + formaldehyde + H2O + NADP(+)


name: CHSY1 transfers GlcA to chondroitin (Mus musculus)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADH + O2 => 4beta-hydroxymethyl-4alpha-methylzymosterol + H2O + NAD(+)


name: Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA (Homo sapiens)


name: Src activation following P2Y purinoceptor activation (Gallus gallus)


name: H(+) + hispidin + NADH + O2 <=> 3-hydroxyhispidin + H2O + NAD(+)


name: 4-amino-4-deoxyprephenate + NAD(+) => 3-(4-aminophenyl)pyruvate + CO2 + H(+) + NADH


name: MUC20 binds MET and inhibits GRB2 binding (Homo sapiens)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Danio rerio)


name: H2O + norsalsolinol => dopamine + formaldehyde


name: GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Rattus norvegicus)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Canis familiaris)


name: ergosteryl ester + H2O = a carboxylate + ergosterol + H(+)


name: PNP trimer transforms RBV to T-CONH2 (Sus scrofa)


name: [alginate](n) + GDP-alpha-D-mannuronate <=> [alginate](n+1) + GDP + H(+)


name: H(+) + N-acyl-15-methylhexadecasphing-4-enine + phosphocholine => H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine


name: (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O => (3R,6R)-6-hydroxy-3-isopropenylheptanoate + H(+)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Saccharomyces cerevisiae)


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + NADP(+) => 3-oxo-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + H(+) + NADPH


name: estrone 3-O-(beta-D-glucuronate) + H(+) + UDP => estrone + UDP-alpha-D-glucuronate


name: (S)-2-hydroxyglutarate + O2 => 2-oxoglutarate + H2O2


name: Unwinding DNA for the nascent transcript (Schizosaccharomyces pombe)


name: Expression of ARFGAP1 (GAP) (Homo sapiens)


name: L-serine + pyrazole => 3-(pyrazol-1-yl)-L-alanine + H2O


name: Aquaporin-1 passively transports water into cell (Xenopus tropicalis)


name: SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to PKL (Homo sapiens)


name: NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Bos taurus)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Bos taurus)


name: RAF phosphorylates MAP2K dimer (Bos taurus)


name: RUNX2 and RB1 bind the BGLAP gene promoter (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Canis familiaris)


name: 3-dimethylallyl-4-hydroxyphenylpyruvate + diphosphate => 3-(4-hydroxyphenyl)pyruvate + dimethylallyl diphosphate


name: RBP3 transports 11cRAL to rod photoreceptor outer segment (Canis familiaris)


name: ALD3A1 oxidises 4HPCP to CXPA (Danio rerio)


name: acetyl-CoA + deacetylcephalosporin C => cephalosporin C + CoA


name: a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O <=> 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Caenorhabditis elegans)


name: PSMD14 cleaves K63-linked ubiquitin (Plasmodium falciparum)


name: FAD + H(+) + sn-glycerol 3-phosphate => dihydroxyacetone phosphate + FADH2


name: 9beta-pimara-7,15-dien-19-al + O2 + reduced [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-dien-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Drosophila melanogaster)


name: P4HB forms mixed disulphides with Hh precursors (Mus musculus)


name: naphtopyrone YWA1 => H(+) + H2O + norrubrofusarin


name: CMP-N,N-diacetyllegionaminate + diphosphate => CTP + N,N-diacetyllegionaminate


name: Corticotropin cleavage from POMC (Danio rerio)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)


name: (1R,2S,4S)-neoisodihydrocarveol + NAD(+) = (1R,4S)-isodihydrocarvone + H(+) + NADH


name: holo-FDPS dimer binds NBPs (Drosophila melanogaster)


name: 2-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + glycerol + H(+)


name: docosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-docosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: Formation of the GCN5-ATAC complex (Bos taurus)


name: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine <=> phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine


name: Cleavage of C3 by C3 convertases (Canis familiaris)


name: H(+) + prostaglandin E2 + sn-glycero-3-phosphoethanolamine => 2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine + H2O


name: diphosphate + NAD(+) => ATP + beta-nicotinamide D-ribonucleotide + H(+)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Xenopus tropicalis)


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Rattus norvegicus)


name: SEMA4D interacts with Plexin-B1:Met (Gallus gallus)


name: Association of beta-catenin with the destruction complex (Bos taurus)


name: Recruitment of CBL to KIT (Rattus norvegicus)


name: 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADP(+)


name: (2E,5S,6E,8E,10E)-1-aminododeca-2,6,8,10-tetraen-5-ol + pyruvate => (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + L-alanine


name: (2R,3R)-tartrate(in) + sulfate(out) <=> (2R,3R)-tartrate(out) + sulfate(in)


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O


name: Furin cleaves pro-factor X to factor X (Danio rerio)


name: L-aspartate 4-semialdehyde + NADP(+) + phosphate <=> 4-phospho-L-aspartate + H(+) + NADPH


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Bos taurus)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Canis familiaris)


name: Polyubiquitinated NRIF binds to p62 (Sequestosome) (Bos taurus)


name: anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + taxa-4,11-diene


name: 16-hydroxyhexadecanoate + NAD(+) => 16-oxohexadecanoate + H(+) + NADH


name: succinate + ubiquinone-8 <=> fumarate + ubiquinol-8


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Caenorhabditis elegans)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Saccharomyces cerevisiae)


name: H(+) + UDP-alpha-D-glucuronate <=> CO2 + UDP-alpha-D-xylose


name: CBLL1 ubiqutinates the InlA-bound CDH1 complex (Homo sapiens)


name: 2-methylpropan-1-amine + H2O + NADP(+) = 2-methylpropanal + H(+) + NADPH + NH4(+)


name: Interaction of MyoD:E protein with MEF2 (Rattus norvegicus)


name: demethyllactenocin + dTDP-beta-L-mycarose <=> demethylmacrocin + dTDP + H(+)


name: an S-alkyl-L-cysteine <=> 2-aminoprop-2-enoate + an alkyl thiol


name: manganese ion transmembrane transporter activity


name: passive transmembrane transporter activity


name: Phosphorylated MOB1A proteins associate with LATS proteins (Gallus gallus)


name: guanosine(out) + Na(+)(out) = guanosine(in) + Na(+)(in)


name: PRMT6 methylates histone H2A arginine-30 (H2AR29) (Homo sapiens)


name: ITGA4:ITGB1 binds natalizumab (Rattus norvegicus)


name: REG3A,REG3G binds bacterial peptidoglycan (Caenorhabditis elegans)


name: ATP2B4 binds to NOS1, inhibiting it (Sus scrofa)


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Drosophila melanogaster)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Mus musculus)


name: 3-O-(alpha-D-glucosyl)-L-threonyl-[protein] + H(+) + UDP => L-threonyl-[protein] + UDP-alpha-D-glucose


name: Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI (Homo sapiens)


name: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine


name: a long-chain fatty aldehyde + holo-[ACP] + NADP(+) = a long-chain fatty acyl-[ACP] + H(+) + NADPH


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Xenopus tropicalis)


name: S-adenosyl-L-methionine + scutellarein <=> H(+) + S-adenosyl-L-homocysteine + scutellarein 4'-methyl ether


name: 1-chloro-3-nitrobenzene + NADH + O2 = 3-chlorocatechol + NAD(+) + nitrite


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Sus scrofa)


name: (3R)-hydroxybutanoate dimer + (R)-3-hydroxybutanoate + H(+) => (3R)-hydroxybutanoate trimer + H2O


name: H2O + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine => acetate + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine


name: 2,4-didehydro-3-deoxy-L-rhamnonate + H2O => (S)-lactate + H(+) + pyruvate


name: NMT1/2 transfer MYS to GNAT1 (Sus scrofa)


name: Dephosphorylation of phospho-Cdh1 (Danio rerio)


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Rattus norvegicus)


name: SGTA binds Tail-anchored protein (Drosophila melanogaster)


name: MTFMT formylates methionyl-tRNA (Homo sapiens)


name: 1D-myo-inositol 5-phosphate + H2O = myo-inositol + phosphate


name: 6-phospho-D-gluconate + NADP(+) <=> CO2 + D-ribulose 5-phosphate + NADPH


name: chrodrimanin T + H(+) + NADPH + O2 => chrodrimanin A + H2O + NADP(+)


name: (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine => 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphocholine + CoA


name: 2-methoxyestrone + UDP-alpha-D-glucuronate = 2-methoxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: 5alpha-cholesta-7,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 7-dehydrodesmosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: MEOS oxidizes ethanol to acetaldehyde (Homo sapiens)


name: Ral-GDS binds to Ras-GTP (Gallus gallus)


name: Salvage - Sepiapterin is reduced to BH2 (Bos taurus)


name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Sus scrofa)


name: AH2 + chermesin D methyl ester <=> A + asnovolin J


name: (Z)-desulfoglucotropeolin + 3'-phosphoadenylyl sulfate <=> (Z)-glucotropeolin + adenosine 3',5'-bisphosphate + H(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: cytidine(48) in tRNA + S-adenosyl-L-methionine => 5-methylcytidine(48) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + alpha,alpha-trehalose => 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+)


name: NOTUM releases Hh-Np:GPC5 from the plasma membrane (Danio rerio)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: H2O + N(6)-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein] <=> glycolate + H(+) + L-lysyl-[protein]


name: Noradrenaline is converted to adrenaline (Bos taurus)


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Gallus gallus)


name: acetyl-CoA + cortisol => CoA + cortisol 21-acetate


name: NADPH + 2 O2 + prefumagillin = acetaldehyde + fumagillin + H2O + NADP(+)


name: NPM1 binds TFAP2A homodimer (Sus scrofa)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Schizosaccharomyces pombe)


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-methionine


name: 1,2-dioctadecanoyl-sn-glycero-3-phosphate + H2O <=> 1,2-dioctadecanoyl-sn-glycerol + phosphate


name: 2-chloro-6-hydroxy-1,4-benzoquinone + 2 chloride + FAD + 3 H(+) => 2,4,6-trichlorophenol + FADH2 + O2


name: L-cysteinyl-[NO transferase protein] + N(omega)-hydroxy-L-arginine + O2 => H(+) + H2O + L-citrulline + S-nitroso-L-cysteinyl-[NO transferase protein]


name: cyanidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose) activity


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Canis familiaris)


name: Cleavage of the signal peptide of Preproghrelin (Mus musculus)


name: aminoacetone + H(+) + NADH => (R)-1-aminopropan-2-ol + NAD(+)


name: 2 chloride(in) + hydrogencarbonate(out) => 2 chloride(out) + hydrogencarbonate(in)


name: IkB is ubiquitinated and degraded (Sus scrofa)


name: 3-oxo-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+)


name: CDK1 phosphorylates RUNX2 (Homo sapiens)


name: catechol + H2O + 2 NADP(+) + nitrite => 2-nitrophenol + 2 H(+) + 2 NADPH + O2


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Sus scrofa)


name: GTP + L-histidyl-[RNA ligase] <=> diphosphate + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase]


name: MT-CO3, COX6A,B,7A and NDUFA4 bind to holo-MT-CO1,2 complex (Bos taurus)


name: CI75 transports from the cytosol to the nucleus (Drosophila melanogaster)


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Mus musculus)


name: AKAP5 recruits PKC to ROBO3.1 (Homo sapiens)


name: 2-octanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + octanoate => 1,2-dioctanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O


name: a 1-acyl-sn-glycero-3-phosphocholine + H2O => a 1-acyl-sn-glycero-3-phosphate + choline + H(+)


name: a ganglioside GP1c + H2O = a ganglioside GQ1c + N-acetylneuraminate


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Mus musculus)


name: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-(4-hydroxyphenyl)acetaldehyde oxime


name: L-ornithine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) => L-ornithine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: PM20D1 hydrolyzes oleoyl-phe (Canis familiaris)


name: H2O + L-alanyl-L-glutamine = L-alanine + L-glutamine


name: JAK1 phosphorylates STAT3,STAT6 (Mus musculus)


name: Glucagon binds to Glucagon receptor (Sus scrofa)


name: (2R,9S)-annullatin H + A => (2R)-annullatin F + AH2


name: 1D-myo-inositol 1,4,5-trisphosphate + phosphate => 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O


name: fatty acid in-chain hydroxylase activity


name: MAP1LC3B binds KEAP1 and SQSTM1 (Danio rerio)


name: acetyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 2 CO2 + 3 CoA + triacetate lactone


name: HSD17B11 dehydrogenates EST17b to E1 (Canis familiaris)


name: ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+) + NADPH => ergosterol + NADP(+)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Drosophila melanogaster)


name: acarbose + ATP => acarbose 7(IV)-phosphate + ADP + H(+)


name: ecdysone 22-phosphate + H2O = ecdysone + phosphate


name: CL-LK binds carbohydrates on target cell surface (Canis familiaris)


name: ALOX5 binds ALOX5 inhibitors (Mus musculus)


name: a triacyl-sn-glycerol + H2O => a 2,3-diacyl-sn-glycerol + a fatty acid + H(+)


name: H2O + substance P => L-Leu-L-Met-NH2 + substance P(1-9)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ATP + H2O <=> a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ADP + H(+) + phosphate


name: Formation of Classical C3 convertase (C4b:C2a complex) (Mus musculus)


name: aniline + H(+) + L-glutamate => H2O + N(5)-phenyl-L-glutamine


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) (Bos taurus)


name: ATP + cadaverine + L-glutamate = ADP + gamma-L-glutamylcadaverine + H(+) + phosphate


name: betaenone A + H(+) + NADPH + O2 => H2O + NADP(+) + stemphyloxin II


name: JUNB dimer binds GZMB promoter (Homo sapiens)


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Bos taurus)


name: acetyl-CoA + AH2 + H(+) + 3 malonyl-CoA + 2 S-adenosyl-L-methionine <=> A + clavatol + 3 CO2 + 4 CoA + H2O + 2 S-adenosyl-L-homocysteine


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Rattus norvegicus)


name: SLC4A4 cotransports Na+ with 3HCO3- (Caenorhabditis elegans)


name: H(+) + keto-D-tagatose 6-phosphate + NADH => galactitol 1-phosphate + NAD(+)


name: Priming and Initiation of Transcription (Homo sapiens)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Xenopus tropicalis)


name: Internal Methylation of mRNA (Mus musculus)


name: Release of novel PDGFs as latent factors (Homo sapiens)


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Gallus gallus)


name: (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + O2 => (3R,6R)-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: 3-O-beta-D-glucosyl-D-glucuronate + phosphate = aldehydo-D-glucuronate + alpha-D-glucose 1-phosphate


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Gallus gallus)


name: Recruited STAT5 is phosphorylated (Homo sapiens)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Mus musculus)


name: Persulfide sulfur is transferred onto sulfite (Homo sapiens)


name: CD22 binds itself to form homo-oligomers (Homo sapiens)


name: 1-O-acyl-N-(acetyl)-sphing-4-enine + 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine


name: Activation of C1r within the C1complement complex (Gallus gallus)


name: SEC4C,D bind GOSR2 and STX5 (Homo sapiens)


name: Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Bos taurus)


name: GSDMD oligomerizes into arc-, slit-shaped structures (Bos taurus)


name: PGH2 is degraded to 12S-HHT and MDA by TBXAS1 (Bos taurus)


name: Fibronectin degradation by MMP14 (Mus musculus)


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Mus musculus)


name: H(+) + NADH + O2 + p-cumate = (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+)


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Bos taurus)


name: alpha-D-ribose 1-phosphate + xanthine => phosphate + xanthosine


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate <=> (+)-valencene + diphosphate


name: SUMOylation of HDAC1 with SUMO1 (Homo sapiens)


name: a 5,6-dihydrouridine in tRNA + NAD(+) <=> a uridine in tRNA + H(+) + NADH


name: L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> H(+) + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + UDP


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate


name: H2O + juvenile hormone II = H(+) + juvenile hormone II carboxylate + methanol


name: Interaction of Tie2 and Shc1 (Mus musculus)


name: gibberellin A13,oxoglutarate:oxygen oxidoreductase activity


name: I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen (Mus musculus)


name: 3,5-dichlorocatechol + O2 = (2E,4E)-2,4-dichloromuconate + 2 H(+)


name: Recruitment of CDK11p58 to the centrosomes (Rattus norvegicus)


name: Release of GNB5:RGS dimers from CCT/TRiC (Rattus norvegicus)


name: 3-(all-trans-hexaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> 2-methoxy-6-(all-trans-hexaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: EDNRA, EDNRB bind non-selective ERAs (Gallus gallus)


name: ESR1 binds to TFF1 gene promoter (Rattus norvegicus)


name: Oxidative demethylation of 1-meA damaged DNA By ALKBH3 (Homo sapiens)


name: Synthesis of dolichyl-phosphate-glucose (Rattus norvegicus)


name: Joining of adjacent Okazaki fragments of the C-strand (Rattus norvegicus)


name: Hydrolysis of PIP3 to PI(3,4)P2 (Xenopus tropicalis)


name: L-cysteate + phosphate => H(+) + O-phospho-L-serine + sulfite


name: Factor H binds host cell surface markers (Sus scrofa)


name: D-aspartate transmembrane transporter activity


name: Caspase-mediated cleavage of Desmoglein 2 (Danio rerio)


name: GH:GHR:JAK2 complex undergoes a conformational change (Mus musculus)


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Xenopus tropicalis)


name: RHOBTB1 binds GTP (Drosophila melanogaster)


name: PIR oxygenates quercetin (Canis familiaris)


name: Formation of AT-AC C complex (Homo sapiens)


name: NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Drosophila melanogaster)


name: Caspase mediated cleavage of alpha-II-Fodrin (Sus scrofa)


name: a quinol + CO2 => a quinone + formate + H(+)


name: p-EPHB phosphorylates SDC2 (Caenorhabditis elegans)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Canis familiaris)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Schizosaccharomyces pombe)


name: LIN7, CASK and APBA1 bind (Rattus norvegicus)


name: L-asparagine(in) + L-glutamine(out) + Na(+)(out) = L-asparagine(out) + L-glutamine(in) + Na(+)(in)


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Caenorhabditis elegans)


name: OPN (osteopontin) degradation by MMP3, MMP7 (Sus scrofa)


name: 1-acyl LPS is acylated to PS by LPSAT (Drosophila melanogaster)


name: SRMS phosphorylates PTK6 (Rattus norvegicus)


name: AMY1-3 bind pramlintide (Xenopus tropicalis)


name: 2 Fe(III)-[cytochrome c] + hydroxylamine => 2 Fe(II)-[cytochrome c] + 2 H(+) + nitroxyl


name: (3,5-dihydroxyphenyl)acetyl-CoA + O2 => 2-(3,5-dihydroxyphenyl)-2-oxoacetate + CoA + H(+)


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Dictyostelium discoideum)


name: PTENP1 mRNA binds miR-20 RISC (Homo sapiens)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Bos taurus)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Drosophila melanogaster)


name: 16alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + progesterone + reduced [NADPH--hemoprotein reductase]


name: H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein] => L-lysyl-[protein] + octanoyl-[ACP]


name: ATP + L-glutamate <=> ADP + L-glutamyl 5-phosphate


name: (E)-hexadec-2-enoate(out) + ATP(in) + CoA(in) + H(+)(out) <=> (2E)-hexadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: all-trans-zeaxanthin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: D-proline(out) + H(+)(out) => D-proline(in) + H(+)(in)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Rattus norvegicus)


name: Myoglobin:oxygen dissociates (Gallus gallus)


name: 3-(methylsulfanyl)acryloyl-CoA + reduced [electron-transfer flavoprotein] => 3-(methylsulfanyl)propanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: COPII coat binds TRAPPCII and RAB1:GDP (Dictyostelium discoideum)


name: H2O + N(5)-ethyl-L-glutamine <=> ethylamine + L-glutamate


name: a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: acetyl-CoA + N-terminal L-threonyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-threonyl-[protein]


name: dihydroxyfumarate + H(+) => 2-hydroxy-3-oxopropanoate + CO2


name: Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Danio rerio)


name: Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV (Danio rerio)


name: a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA <=> (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)


name: 4-O-(beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + H2O = 4-O-(beta-L-arabinofuranosyl)-(2S,4S)-4-hydroxyproline + beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose


name: Formation of Elongin BC complex (Xenopus tropicalis)


name: 9beta-pimara-7,15-dien-19-al + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-dien-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTPRF, PTPRS, PTPRD bind Liprins (Canis familiaris)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) => (6R)-L-erythro-6,7-dihydrobiopterin + H(+) + NADPH


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Homo sapiens)


name: USP12, USP26 deubiquitinate AR (Canis familiaris)


name: CoA + NADP(+) + pyruvate => acetyl-CoA + CO2 + NADPH


name: H(+)(out) + L-alanyl-L-leucyl-L-alanine(out) = H(+)(in) + L-alanyl-L-leucyl-L-alanine(in)


name: OTUB1, (OTUB2) binds RNF128, TRAF3, TRAF6, RHOA (Sus scrofa)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Bos taurus)


name: HSF1 acetylation at Lys80 (Rattus norvegicus)


name: CDP-6-keto-D-fructose + diphosphate => CTP + H(+) + keto-D-fructose 6-phosphate


name: 2-hydroxyhexadecanoate + ATP + CoA <=> 2-hydroxyhexadecanoyl-CoA + AMP + diphosphate


name: NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Canis familiaris)


name: Dopa is decarboxylated to dopamine (Mus musculus)


name: (9E,11E)-octadecadienoate + H2O <=> 10-hydroxy-(11E)-octadecenoate


name: CTLA4 gene expression is stimulated by FOXP3 and inhibited by RUNX1 (Homo sapiens)


name: uridine(746) in 23S rRNA <=> pseudouridine(746) in 23S rRNA


name: 2-methylpropanenitrile + H2O => (Z)-2-methylpropanal oxime


name: HK1 phosphorylates Mannose to Man6P (Saccharomyces cerevisiae)


name: 7,8-dihydroxykynurenate + O2 <=> 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+)


name: L-methionine + S-adenosyl-L-methionine <=> S-adenosyl-L-homocysteine + S-methyl-L-methionine


name: H2O + N,N-dimethylglycine + O2 <=> formaldehyde + H2O2 + sarcosine


name: a monoacylglycerol + ATP <=> ADP + H(+) + monoacyl-sn-glycero-3-phosphate


name: 2 (S)-methylmalonyl-CoA + 10 H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 3 malonyl-CoA + 5 NADPH = C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)


name: ATP + cob(I)inamide-[corrinoid adenosyltransferase] <=> adenosylcob(III)inamide + apo-[corrinoid adenosyltransferase] + triphosphate


name: Formation of the IGF:IGFBP3:ALS complex (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (R)-axinyssene + diphosphate


name: ATP + Fe(III)-enterobactin(out) + H2O <=> ADP + Fe(III)-enterobactin(in) + H(+) + phosphate


name: CYP2A13 oxidises AFM1 to AFM1E (Danio rerio)


name: ADP-L-glycero-beta-D-manno-heptose + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O = 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + choline + H(+)


name: 3',5'-cyclic AMP(in) <=> 3',5'-cyclic AMP(out)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HK1 phosphorylates Mannose to Man6P (Plasmodium falciparum)


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] <=> akuammicine + formate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IL35 binds IL-12RB2:IL6ST receptor (Bos taurus)


name: campesterol + UDP-alpha-D-glucose => campesteryl 3-beta-D-glucoside + H(+) + UDP


name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate (Drosophila melanogaster)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Rattus norvegicus)


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Drosophila melanogaster)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Saccharomyces cerevisiae)


name: L-arogenate + NAD(+) => CO2 + L-tyrosine + NADH


name: 2-oxindole-3-acetate + succinyl-CoA = (2-oxoindol-3-yl)acetyl-CoA + succinate


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Drosophila melanogaster)


name: D-glucono-1,5-lactone + H2O = D-gluconate + H(+)


name: Expression of CCRN4L (NOCTURNIN) (Homo sapiens)


name: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + H(+)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Xenopus tropicalis)


name: (Z)-N-(sulfonatooxy)prop-2-enimidothioate <=> allyl isothiocyanate + sulfate


name: an N-acyl-sphinga-4E,14Z-dienine + CoA + H(+) => a fatty acyl-CoA + sphinga-4E,14Z-dienine


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Bos taurus)


name: avenacoside A + H2O = 26-desgluco-avenacoside A + D-glucose


name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (Mus musculus)


name: IFNAR1:TYK2 binds TYK2 inhibitors (Xenopus tropicalis)


name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate => (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2


name: AH2 + O2 + preaustinoid A => A + H2O + preaustinoid A1


name: Gamma-secretase cleaves YBX1:NOTCH3 (Rattus norvegicus)


name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 (Rattus norvegicus)


name: COQ4 decarboxylates MHDB (Rattus norvegicus)


name: Endonucleolytic RISC hydrolyzes target RNAs (Sus scrofa)


name: 2-oxoglutarate + gibberellin A15 + O2 => CO2 + gibberellin A24 + H2O + succinate


name: Disassembly of tight junctions (Caenorhabditis elegans)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O => a fatty acid + H(+) + sn-glycero-3-phosphoethanolamine


name: lithocholate + NADP(+) => 3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: (E)-coniferaldehyde + H2O + NAD(+) = (E)-ferulate + 2 H(+) + NADH


name: (1R,8aS)-octahydroindolizin-1-ol + CO2 + CoA + 2 H2O + 3 NADP(+) => 5 H(+) + L-pipecolate + malonyl-CoA + 3 NADPH


name: genistein + O2 + reduced [NADPH--hemoprotein reductase] = 2'-hydroxygenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CPO transforms COPRO3 to PPGEN9 (Danio rerio)


name: Dephosphorylation of p130 (RBL2) by PP2A (Dictyostelium discoideum)


name: 2 2-iminio-3-(indol-3-yl)propanoate + H2O2 = 2 H2O + indole-3-pyruvate imine dimer


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: L-cysteine + sulfite <=> hydrogen sulfide + L-cysteate


name: BRCA1 forms a heterodimer with BARD1 (Mus musculus)


name: 1-O-(trans-4-coumaroyl)-beta-D-glucose + cyanidin 3-O-(6-O-glucosyl-2-O-xylosylgalactoside) betaine = beta-D-glucose + cyanidin 3-O-[6-O-(6-O-4-hydroxycinnamoyl-beta-D-glucosyl)-2-O-beta-D-xylosyl-beta-D-galactoside] + H(+)


name: beta-L-fucose 1-phosphate + GTP + H(+) = diphosphate + GDP-beta-L-fucose


name: beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA (Caenorhabditis elegans)


name: PIAS4 SUMOylates PPARA with SUMO1 (Homo sapiens)


name: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + CMP + H(+) => a neolactoside nLc4Cer + CMP-N-acetyl-beta-neuraminate


name: 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase] = 9beta-pimara-7,15-diene-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HCCS inserts heme into cytochrome c (Drosophila melanogaster)


name: Dissociation of Cdc20 from APC/C complex (Bos taurus)


name: 15-cis-phytoene + 2 a plastoquinone => 9,9',15-tri-cis-zeta-carotene + 2 a plastoquinol


name: Formation of Cyclin A:Cdk2 complexes (Homo sapiens)


name: (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 = (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: PNPLA4 hydrolyzes retinyl palmitate (Xenopus tropicalis)


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Mus musculus)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Xenopus tropicalis)


name: (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + 2 H2O + NADP(+) <=> (4S)-4-hydroxy-L-glutamate + H(+) + NADPH


name: Activation of Rap1 by membrane-associated GEFs (Gallus gallus)


name: a fatty acid(out) + ATP + H2O = a fatty acid(in) + ADP + H(+) + phosphate


name: cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Rattus norvegicus)


name: ATP + 2 H2O = AMP + 2 H(+) + 2 phosphate


name: p-4Y-SIRPA:CD47 binds GRB2-1 (Sus scrofa)


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Sus scrofa)


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Canis familiaris)


name: a 1,2-diacyl-sn-glycerol(in) = a 1,2-diacyl-sn-glycerol(out)


name: 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine => 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Bos taurus)


name: AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Homo sapiens)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Caenorhabditis elegans)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Dictyostelium discoideum)


name: all-trans-3,4-didehydroretinol + 2 H2O + 2 oxidized [adrenodoxin] => all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: D-ribitol 1-phosphate + H2O = phosphate + ribitol


name: PCho is dephosphorylated to Cho by PHOSPHO1 (Drosophila melanogaster)


name: SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Canis familiaris)


name: a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O => 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Mus musculus)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Homo sapiens)


name: alpha-D-glucose 1-phosphate + CTP + H(+) = CDP-D-glucose + diphosphate


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Bos taurus)


name: (R)-pulegone + O2 + reduced [NADPH--hemoprotein reductase] <=> (R)-menthofuran + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + [ribosomal protein uS12]-L-proline + O2 <=> [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + CO2 + succinate


name: [Rab1 protein]-O-phosphocholine-L-serine + CMP + H(+) => [Rab1 protein]-L-serine + CDP-choline


name: ATR phosphorylates TP53 (Rattus norvegicus)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Mus musculus)


name: 3-bromo-2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine => 3-bromo-2-heptyl-1-methoxy-4(1H)-quinolinone + H(+) + S-adenosyl-L-homocysteine


name: Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Rattus norvegicus)


name: a carboxylate + NH4(+) => a nitrile + 2 H2O


name: Phosphorylation of L1 by ERK (Dictyostelium discoideum)


name: L-dopa(in) + L-phenylalanine(out) => L-dopa(out) + L-phenylalanine(in)


name: PINK1 phosphorylates Ub on MOM proteins (Drosophila melanogaster)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Caenorhabditis elegans)


name: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH


name: miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 11-oxomiltiradiene + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: GluN1:GluN2B (GRIN1:GRIN2B) di-heterotetramers bind LIN7:CASK:APBA1, DLG1 and KIF17 (Homo sapiens)


name: Proteasomal clevage of exogenous antigen (Drosophila melanogaster)


name: H(+) + homogentisate + phytyl diphosphate => 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate


name: CX3 complex formation (Plasmodium falciparum)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Danio rerio)


name: dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-adenosyl-L-methionine <=> dTDP-D-ravidosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Schizosaccharomyces pombe)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Sus scrofa)


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Sus scrofa)


name: SHP2 binds to the active receptor (Mus musculus)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Xenopus tropicalis)


name: beta-catenin is replaced by repression complexes at the promoter (Homo sapiens)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Mus musculus)


name: agmatine + H2O + O2 <=> 4-guanidinobutanal + H2O2 + NH4(+)


name: 3,4,5-trihydroxybenzoate + UDP-alpha-D-glucose => 1-O-galloyl-beta-D-glucose + UDP


name: Translocation of ISGF3 complex to nucleus (Rattus norvegicus)


name: Myoglobin:oxygen dissociates (Danio rerio)


name: (3R)-hydroxyhexanoyl-[ACP] = (2E)-hexenoyl-[ACP] + H2O


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Saccharomyces cerevisiae)


name: 3-oxosphinganine + docosanoyl-CoA => CoA + H(+) + N-docosanoyl-3-ketodihydrosphingosine


name: Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Gallus gallus)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoylglycerol = 1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Canis familiaris)


name: YME1L1 proteolyzes unassembled proSMDT1 (Mus musculus)


name: 3 Na(+)(out) + sulfate(out) <=> 3 Na(+)(in) + sulfate(in)


name: (+)-copalyl diphosphate => abieta-7,13-diene + diphosphate


name: P2X1-mediated entry of Ca++ from plasma (Xenopus tropicalis)


name: PKC phosphorylates GRK2 (Drosophila melanogaster)


name: (S)-reticuline + S-adenosyl-L-methionine <=> (S)-tembetarine + H(+) + S-adenosyl-L-homocysteine


name: 3,17-didehydrostemmadenine + H2O + NADPH => (16S)-deshydroxymethyl-stemmadenine + formate + NADP(+)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP-alpha-D-glucose => 2 H(+) + ternatin C5 + UDP


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate <=> (14S,15S)-epoxy-(5Z,8Z,10E,12E)-eicosatetraenoate + H2O


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Mus musculus)


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Danio rerio)


name: H2O + N(6)-acetyl-L-lysyl-[protein] + O2 <=> (S)-2-amino-6-oxohexanoyl-[protein] + acetamide + H2O2


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Schizosaccharomyces pombe)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Schizosaccharomyces pombe)


name: 8'-apo-beta-carotenol + O2 = (3E,5E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal


name: CoA + H(+) + N(6)-decanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] => decanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: ORC1 binds to H4K20me2 (Canis familiaris)


name: 3',3'-cGAMP(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in) <=> 3',3'-cGAMP(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out)


name: H(+) + keto-D-fructuronate + NADH => L-gulonate + NAD(+)


name: a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + H(+) + UDP => a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine


name: 2-oxoglutarate + codeine + O2 <=> CO2 + formaldehyde + morphine + succinate


name: glucose 1-dehydrogenase [NAD(P)+] activity


name: TRiC/CCT binds unfolded G-protein beta subunit (Danio rerio)


name: protein tyrosine/threonine phosphatase activity


name: IL4:IL4R:JAK2 binds IL13RA1:TYK2 (Rattus norvegicus)


name: WLS:WNT complex is internalized for maturation into exosomes (Xenopus tropicalis)


name: HS3ST1 sulfates GlcN at C3 in heparan sulfate (Homo sapiens)


name: apigenin + S-adenosyl-L-methionine => acacetin + H(+) + S-adenosyl-L-homocysteine


name: 6-methylpretetramide + 2 H(+) + NADPH + O2 <=> 4-hydroxy-6-methylpretetramide + H2O + NADP(+)


name: dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] <=> CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: NAD(+) + sn-glycerol 3-phosphate <=> dihydroxyacetone phosphate + H(+) + NADH


name: D-maltohexaose + O2 <=> D-maltohexaono-1,5-lactone + H2O2


name: 1D-myo-inositol 2,3-bisphosphate + phosphate => 1D-myo-inositol 1,2,3-trisphosphate + H2O


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Xenopus tropicalis)


name: ATP + keto-D-tagatose => ADP + H(+) + keto-D-tagatose 6-phosphate


name: H(+) + NADPH + undecanal => NADP(+) + undecan-1-ol


name: cholestanol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-26-hydroxycholestanol + H2O + 2 oxidized [adrenodoxin]


name: miR-21 nonendonucleolytic RISC binds PTEN mRNA (Homo sapiens)


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Rattus norvegicus)


name: 3-(methylsulfanyl)acryloyl-CoA + 2 H2O => acetaldehyde + CO2 + CoA + methanethiol


name: adenosine 3',5'-bisphosphate + 2 H(+) + succinyl-4'-phosphopantetheine => H2O + succinyl-CoA


name: a dodecanoate ester + H2O <=> an aliphatic alcohol + dodecanoate + H(+)


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Bos taurus)


name: MRN complex binds shortened telomeres (Homo sapiens)


name: Formation of collagen fibres (Caenorhabditis elegans)


name: D-tagatopyranose 1-phosphate + NH4(+) => D-galactosamine 6-phosphate + H2O


name: D-maltohexaono-1,5-lactone + H2O = D-maltohexaonate + H(+)


name: LIG1 binds POLB at long-patch BER site (Dictyostelium discoideum)


name: a (2E,4Z)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(2E)-enoyl-CoA + NADP(+)


name: PTPRJ dephosphorylates active FLT3 (Homo sapiens)


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Caenorhabditis elegans)


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + H(+) + S-adenosyl-L-homocysteine => (4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + S-adenosyl-L-methionine


name: 2-oxoglutarate + L-asparaginyl-[protein] + O2 <=> (3S)-3-hydroxy-L-asparaginyl-[protein] + CO2 + succinate


name: ATM phosphorylates DYRK2 (Rattus norvegicus)


name: 1-hexanoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+) => 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O


name: bilirubin IXbeta + NADP(+) => biliverdin IXbeta + H(+) + NADPH


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) <=> 4,5-dihydroxyphthalate + H(+) + NADH


name: fluoride + glycolate + H(+) => fluoroacetate + H2O


name: 3-oxoadipate + acetyl-CoA <=> acetoacetate + succinyl-CoA


name: 2 mycothiol + NAD(+) => H(+) + mycothione + NADH


name: Acidification of Tf:TfR1 containing endosome (Canis familiaris)


name: Src kinases phosphorylate VAV (Rattus norvegicus)


name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Canis familiaris)


name: nitric oxide dioxygenase activity, heme protein as donor


name: Fe(II)-heme b-[protein] + nitric oxide + O2 = Fe(III)-heme b-[protein] + nitrate


name: ITGA4:ITGB1 binds natalizumab (Mus musculus)


name: ASAP1 stimulates GTPase activity of ARF4 (Rattus norvegicus)


name: GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC (Bos taurus)


name: ZnT5 transports zinc into the golgi apparatus (Mus musculus)


name: NAD(+) + resolvin D1 = 17-oxoresolvin D1 + H(+) + NADH


name: 1-acyl-2-(9Z)-enoyl-sn-glycero-3-phospholipid + S-adenosyl-L-methionine => 1-acyl-2-(9-cyclopronane)-acyl-sn-glycero-3-phospholipid + H(+) + S-adenosyl-L-homocysteine


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Plasmodium falciparum)


name: Formation of a heteromeric BMP receptor complex (Bos taurus)


name: Dissociation of IRS-P from insulin receptor (Gallus gallus)


name: NAA translocates from mitochondrial matrix to cytosol (Homo sapiens)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Mus musculus)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)


name: Beclin-1 complex translocates to the ER (Mus musculus)


name: p190RhoGAP binds Plexin-B1 (Xenopus tropicalis)


name: PTK2 autophosphorylates downstream of EGFR (Gallus gallus)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Gallus gallus)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Schizosaccharomyces pombe)


name: beta-D-fructose 1-phosphate = D-glyceraldehyde + dihydroxyacetone phosphate


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Sus scrofa)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Xenopus tropicalis)


name: Phosphorylation of INFAR1 by TYK2 (Bos taurus)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate => (+)-delta-selinene + diphosphate


name: L-proline + NADP(+) => 1-pyrroline-2-carboxylate + H(+) + NADPH


name: an N-acylsphing-4-enine 1-phosphate + choline + H(+) => a sphingomyelin + H2O


name: 4-amino-L-phenylalanine + ATP + holo-[peptidyl-carrier protein] => 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AMP + diphosphate


name: Interaction of Tie2 and Shc1 (Homo sapiens)


name: ATP + H2O + pyruvate <=> AMP + 2 H(+) + phosphate + phosphoenolpyruvate


name: GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Drosophila melanogaster)


name: 2-dehydro-3-deoxy-L-fuconate = (S)-lactaldehyde + pyruvate


name: HTR3A antagonists bind HTR3A pentamer (Mus musculus)


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Rattus norvegicus)


name: TFAM binds to mitochondrial promoters (Drosophila melanogaster)


name: Na(+)(in) + O-propanoyl-(R)-carnitine(in) => Na(+)(out) + O-propanoyl-(R)-carnitine(out)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Gallus gallus)


name: dimethylallyl diphosphate + H2O <=> dimethylallyl phosphate + H(+) + phosphate


name: Glutamine transport from astrocytes (Canis familiaris)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[16] (Sus scrofa)


name: (2E)-geranyl diphosphate => alpha-pinene + diphosphate


name: 6-O-methyl-N-deacetylipecoside aglycone + D-glucose => 6-O-methyl-N-deacetylipecoside + H2O


name: 2'-hydroxy-2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2',2'-dihydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Homo sapiens)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Homo sapiens)


name: (S,S)-tartrate(out) + succinate(in) => (S,S)-tartrate(in) + succinate(out)


name: acetylcholine + H2O = acetate + choline + H(+)


name: CoA + eicosanyl hexadecanoate => eicosan-1-ol + hexadecanoyl-CoA


name: (R)-adrenaline + S-adenosyl-L-methionine <=> (R)-metanephrine + H(+) + S-adenosyl-L-homocysteine


name: 8-methylquinoline + A + H2O <=> 8-methylquinolin-2(1H)-one + AH2


name: adenosine 3'-diphosphate,5'-phosphate + AMP + H(+) => AMP + ATP


name: LEF1, CTNNB1 and MITF-M bind the MITF gene (Homo sapiens)


name: a ganglioside Gal-GD1b + GDP-beta-L-fucose = a ganglioside Gal(Fuc)-GD1b + GDP + H(+)


name: O2 + Watasenia luciferin <=> CO2 + hnu + oxidized Watasenia luciferin


name: H2O + NADP(+) + notoamide D => H(+) + NADPH + notoamide E + O2


name: D-aspartate(in) + sulfate(out) => D-aspartate(out) + sulfate(in)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Drosophila melanogaster)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2A (GRIN2A) and GluN2C (GRIN2C) (Homo sapiens)


name: (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: an (11Z,14Z,17Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2'-deoxyguanosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + guanine


name: ATP + H2O + sitosterol(in) = ADP + H(+) + phosphate + sitosterol(out)


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Rattus norvegicus)


name: 2 NADP(+) + tetrahydrocurcumin => curcumin + 2 H(+) + 2 NADPH


name: (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine => S-(5-deoxy-D-ribos-5-yl)-L-homocysteine


name: Transfer of ubiquitin from E1 to E2 (Plasmodium falciparum)


name: tRNA pseudouridine(38/39) synthase activity


name: gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => gypsogenin + O2 + reduced [NADPH--hemoprotein reductase]


name: CLK:CYC heterodimer binds to cwo gene and activates transcription (Drosophila melanogaster)


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Xenopus tropicalis)


name: Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)


name: MAT1A multimers transfer Ado from ATP to L-Met (Sus scrofa)


name: H(+) + lanosterol + NADPH <=> 24,25-dihydrolanosterol + NADP(+)


name: ADP + H(+) + N-acetyl-L-aspartyl-L-glutamate(out) + phosphate => ATP + H2O + N-acetyl-L-aspartyl-L-glutamate(in)


name: (S,S)-tartrate(in) + sulfate(out) <=> (S,S)-tartrate(out) + sulfate(in)


name: DLST transfers glutaryl to CoA (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O <=> (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: RHOV binds GTP (Dictyostelium discoideum)


name: Thrombin-activated PARs activate G12/13 (Caenorhabditis elegans)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Sus scrofa)


name: L-glucitol + NAD(+) => H(+) + keto-L-fructose + NADH


name: maleate(in) + sulfate(out) <=> maleate(out) + sulfate(in)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Drosophila melanogaster)


name: RPE dimers isomerise RU5P to XY5P (Rattus norvegicus)


name: 1,4-dithiothreitol + 2,3-epoxyphylloquinone => 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + oxidized dithiothreitol


name: HTN1,HTN3 or HTN5 binds the bacterial anionic surface  (Bos taurus)


name: The p75NTR:NgR:MDGI binds RHOA-GDI (Homo sapiens)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Danio rerio)


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Caenorhabditis elegans)


name: 3alpha-hydroxy-5alpha-pregnan-20-one + NAD(+) = 5alpha-pregnane-3,20-dione + H(+) + NADH


name: Translocation of PDK1 to Plasma membrane (Canis familiaris)


name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density (Homo sapiens)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Sus scrofa)


name: an inositol-1-phosphoceramide + H2O <=> 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)


name: 3',5'-di-O-methyltricetin + S-adenosyl-L-methionine => 3',4',5'-O-trimethyltricetin + H(+) + S-adenosyl-L-homocysteine


name: isocitrate dehydrogenase [NAD(P)+] activity


name: SLC7A11-mediated exchange of extracellular cysteine and cytosolic glutamate (Rattus norvegicus)


name: Interleukin-16 is secreted (Xenopus tropicalis)


name: H(+) + NADH + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose => NAD(+) + UDP-2-acetamido-2,6-dideoxy-beta-L-talose


name: an inositol-1-phosphophytoceramide + beta-D-mannose => a mannosylinositol-1-phosphophytoceramide + H2O


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: all-trans-retinol + NAD(+) => all-trans-retinal + H(+) + NADH


name: 3-amino-4-hydroxybenzaldehyde + acetyl-CoA => 3-acetylamino-4-hydroxybenzaldehyde + CoA + H(+)


name: REST recruits the BHC complex (Sus scrofa)


name: K63polyUb-IRAK1 dissociates (Homo sapiens)


name: H(+)(out) + L-aspartate(in) + phosphate(out) => H(+)(in) + L-aspartate(out) + phosphate(in)


name: an N-acylsphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acylsphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Autocatalytic phosphorylation of FGFR3 cysteine mutants (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] => 17-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sphing-4-enine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + sphing-4-enine


name: H2O + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(9Z-octadecenoyl) ethanolamine


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)


name: (2S)-lactyl-2-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin = GMP + H(+) + oxidized coenzyme F420-0


name: 1D-myo-inositol 1-phosphate + phosphate => 1D-myo-inositol 1,3-bisphosphate + H2O


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus (Danio rerio)


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Canis familiaris)


name: EBP isomerizes ZYMSTNL to LTHSOL (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> allo-aromadendrene + diphosphate


name: MECP2 binds the STAT5A gene (Homo sapiens)


name: [aequorin] + 3 Ca(2+) <=> [aequorin]--dioxetanone


name: Expression of ABCG5 regulated by NR1H2,3 (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol + diphosphate


name: diphosphate + GMP => 5-phospho-alpha-D-ribose 1-diphosphate + guanine


name: ADP + L-glutamine hydroxamate + phosphate => ATP + hydroxylamine + L-glutamate


name: phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Rattus norvegicus)


name: an N-acylsphing-4-enine 1-phosphate + H2O <=> an N-acylsphing-4-enine + phosphate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O => (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 3-meC (Homo sapiens)


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate => alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: (2R)-annullatin F + AH2 => (2R,9S)-annullatin H + A


name: p-S407,Y641-STAT6 is dimerized (Drosophila melanogaster)


name: Hv1 Mediated H+ Permeability (Rattus norvegicus)


name: [phosphate](n) + a dolichyl diphosphate => [phosphate](n+1) + a dolichyl phosphate


name: 2,5-dioxopentanoate + H2O + NAD(+) <=> 2-oxoglutarate + 2 H(+) + NADH


name: (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+) => 1,2,3-trihydroxybenzene + O2


name: FA2H hydroxylates 1,2-saturated fatty acids (Saccharomyces cerevisiae)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Schizosaccharomyces pombe)


name: 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin] => a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin]


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Rattus norvegicus)


name: UDP-alpha-D-glucuronate + zolasartan <=> UDP + zolarsartan-2-N-beta-D-glucuronide


name: PREDL:ALB dissociates (Xenopus tropicalis)


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + ATP + H2O <=> 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + ADP + H(+) + phosphate


name: 2 Fe(II)-[cytochrome c] + 2 H(+) + N-methylmyosmine => (S)-nicotine + 2 Fe(III)-[cytochrome c]


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Danio rerio)


name: 2-oxoglutarate + L-arginyl-[ribosomal protein eS6] + O2 = (3R)-3-hydroxy-L-arginyl-[ribosomal protein eS6] + CO2 + succinate


name: TRPV1 binds TRPV1 agonists (Mus musculus)


name: AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Mus musculus)


name: aldosterone + H(+) + NADPH <=> 5beta-dihydroaldosterone + NADP(+)


name: (S)-2-hydroxyglutarate(out) + 3 Na(+)(out) => (S)-2-hydroxyglutarate(in) + 3 Na(+)(in)


name: cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine => beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol


name: 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Danio rerio)


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Rattus norvegicus)


name: Dynamin-mediated GTP hydrolysis promotes vesicle scission (Rattus norvegicus)


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Sus scrofa)


name: GPX1 catalyzes reaction of reduced glutathione and H2O2 to form oxidized glutathione and H2O (Sus scrofa)


name: 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine => 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: (2R)-3-phospho-glyceroyl phosphate + GDP => (2R)-3-phosphoglycerate + GTP


name: CYCS:APAF1 binds procaspase-9 (Mus musculus)


name: (S)-N-acetyl-1-phenylethylamine + H2O => (S)-1-phenylethylamine + acetate


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Danio rerio)


name: H2O + L-selenocystathionine => 2-oxobutanoate + L-selenocysteine + NH4(+)


name: Cho is acetylated to AcCho by CHAT (Danio rerio)


name: NOX4, NOX5 reduce O2 to O2.- (Mus musculus)


name: 20alpha-hydroxy-5beta-pregnan-3-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH


name: a globoside Gb3Cer + H2O => a fatty acid + a lysoGb3


name: Interaction of DAP12 and TREM1 (Homo sapiens)


name: Dephosphorylation of STAT1 by SHP2 (Bos taurus)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Canis familiaris)


name: formaldehyde + H2O + NAD(+) + xanthine => 3-methylxanthine + H(+) + NADH + O2


name: H(+) + N-methylheliamine + S-adenosyl-L-homocysteine => heliamine + S-adenosyl-L-methionine


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Canis familiaris)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Canis familiaris)


name: RAC2 binds effectors at the mitochondrial outer membrane (Sus scrofa)


name: KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Gallus gallus)


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Caenorhabditis elegans)


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Bos taurus)


name: an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-cysteinylglycine + L-glutamate => an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H2O


name: RGGT binds the RAB-binding subunit (Bos taurus)


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Drosophila melanogaster)


name: USP20, USP33 deubiquitinate ADRB2 (Canis familiaris)


name: pro-SFTPB translocates from ER membrane to multivesicle body (Gallus gallus)


name: ABCG4 may mediate cholesterol efflux (Mus musculus)


name: ATP + holo-[ACP] + tetradecanoate = AMP + diphosphate + tetradecanoyl-[ACP]


name: medium-chain fatty acid omega-hydroxylase activity


name: FMNH2 + N-acetyl-S-benzyl-L-cysteine + O2 <=> (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Saccharomyces cerevisiae)


name: (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NADP(+) => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + uridine(54) in tRNA


name: USF1 is phosphorylated by p-MAPK14 (Bos taurus)


name: D-alanine(out) + H(+)(out) => D-alanine(in) + H(+)(in)


name: PIAS1 SUMOylates SP3 with SUMO1 (Sus scrofa)


name: D-erythrose + phosphate => D-erythrose 4-phosphate + H2O


name: Exocytosis of specific granule lumen proteins (Rattus norvegicus)


name: 2',3'-cyclophospho-CMP + H2O => cytidine 2'-phosphate + H(+)


name: Interaction of Tie2 and p85 of PI3K (Bos taurus)


name: H(+) + soyasaponin I + UDP => soyasaponin III + UDP-beta-L-rhamnose


name: cholesteryl (9Z-octadecenoate) + H2O => (9Z)-octadecenoate + cholesterol + H(+)


name: STUB1 (CHIP) ubiquitinates SMAD3 (Caenorhabditis elegans)


name: UCHL3, SENP8 cleave NEDD8 (Caenorhabditis elegans)


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Bos taurus)


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Homo sapiens)


name: Phosphorylation of CBL (EGFR:CBL) (Homo sapiens)


name: (2E)-tetradecenoyl-[ACP] + H(+) + NADPH <=> NADP(+) + tetradecanoyl-[ACP]


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Caenorhabditis elegans)


name: Fibrillin-1 binds integrins (Rattus norvegicus)


name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)


name: Nephrin mediated activation of N-WASP (Danio rerio)


name: Exocytosis of tertiary granule membrane proteins (Rattus norvegicus)


name: PC is converted to PS by PTDSS1 (Mus musculus)


name: (3S)-hydroxyoctanoyl-CoA + NAD(+) <=> 3-oxooctanoyl-CoA + H(+) + NADH


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Rattus norvegicus)


name: sn-glycerol 3-phosphate + UDP-alpha-D-galactose => 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP


name: Trans-autophosphorylation of ERBB2 heterodimers (Sus scrofa)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside) in mRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine


name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol (Canis familiaris)


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Rattus norvegicus)


name: RNF181 polyubiquinates BCL10 (Homo sapiens)


name: ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Canis familiaris)


name: RNF146 binds RibC-AXIN:TNKS complex (Gallus gallus)


name: 2 H(+) + NADH + pentanoate => H2O + NAD(+) + pentanal


name: D-5-phenylhydantoin + H2O <=> H(+) + N-carbamoyl-D-phenylglycine


name: an L-alpha-amino acid + L-proline => H2O + Xaa-L-Pro dipeptide


name: Proteasome degrades polyubiquitinated PTEN (Caenorhabditis elegans)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Mus musculus)


name: 3-methylxanthine + H(+) + NADPH + O2 = formaldehyde + H2O + NADP(+) + xanthine


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Schizosaccharomyces pombe)


name: SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Gallus gallus)


name: 3-oxopentanoate + 2 AMP + 4 H(+) + 4 phosphate => 2 ATP + butan-2-one + 3 H2O + hydrogencarbonate


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Drosophila melanogaster)


name: dTMP + H2O = 2-deoxy-D-ribose 5-phosphate + thymine


name: 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH => D-glucose 6-phosphate + NADP(+)


name: RHOD GAPs stimulate RHOD GTPase activity (Canis familiaris)


name: (indol-3-yl)acetate + UDP-alpha-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP


name: OSM,LIF,CTF1 receptor complex binds gp130 (Bos taurus)


name: CTP(out) + dUTP(in) = CTP(in) + dUTP(out)


name: 2-oxoglutarate + gibberellin A14 aldehyde + O2 = CO2 + gibberellin A14 + H(+) + succinate


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA => 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA


name: CBL binds B-cell linker protein (Homo sapiens)


name: Syndecans 1, 2 & 4 bind VTN (Drosophila melanogaster)


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Danio rerio)


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Danio rerio)


name: ASPH:Fe2+ hydroxylates an aspartate residue of F9 (Homo sapiens)


name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 = 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA <=> 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: H(+) + N-acetyl-S-(2-succino)-L-cysteine + NADH + O2 = H2O + N-acetyl-L-cysteine + NAD(+) + oxaloacetate


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Xenopus tropicalis)


name: 4'-O-methylnorbelladine + O2 + reduced [NADPH--hemoprotein reductase] => (10bR,4aS)-noroxomaritidine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Mus musculus)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + H2O + 2 oxidized [adrenodoxin]


name: (2E,6E)-farnesyl diphosphate + CDP => (2E,6E)-farnesyl phosphate + CTP


name: AMP + H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] => ADP + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase]


name: I-Smad competes with Co-Smad for R-Smad1/5/8 (Drosophila melanogaster)


name: Defective IRAK4 variants do not bind MyD88:MAL:BTK:activated TLR2/4 (Homo sapiens)


name: Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)


name: ATP + kanosamine = ADP + D-kanosamine 6-phosphate + H(+)


name: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO2


name: L-ornithine + succinyl-CoA <=> CoA + H(+) + N(2)-succinyl-L-ornithine


name: Degradation of newly synthesized ApoB-48 (Bos taurus)


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate => (1S,2S,4R)-beta-elemene + diphosphate


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Danio rerio)


name: Binding of GRB2:SOS1 complex to phosphorylated ligand-responsive EGFR mutants (Homo sapiens)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Sus scrofa)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA


name: 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] = dehydrocitreoisocoumarin + H2O + holo-[ACP]


name: L-ascorbate(out) + N(pros)-phospho-L-histidyl-[protein] = L-ascorbate 6-phosphate(in) + L-histidyl-[protein]


name: H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate


name: ethylenediaminetriacetate + FMNH2 + O2 => ethylenediaminediacetate + FMN + glyoxylate + H(+) + H2O


name: Association of procollagen type XIX (Homo sapiens)


name: PLK1 hyperphosphorylates Condensin II complex (Canis familiaris)


name: ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Gallus gallus)


name: (S)-2-benzoylsuccinyl-CoA + CoA = benzoyl-CoA + succinyl-CoA


name: A + arsenite + H2O <=> AH2 + arsenate + H(+)


name: AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Bos taurus)


name: gamma-L-glutamyl-hercynylcysteine S-oxide + H2O = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide


name: "gamma-glutamyl hercynylcysteine S-oxide hydrolase"


name: XYLB phosphorylates D-xylulose (Sus scrofa)


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Sus scrofa)


name: MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Bos taurus)


name: RAB33B:GTP binds RIC1:RGP1 (Mus musculus)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Bos taurus)


name: CK1 phosphorylates p-GLI2 (Homo sapiens)


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Drosophila melanogaster)


name: Activation of TAK1 complex bound to activated TLR4 complex (Rattus norvegicus)


name: (2R)-heptan-2-amine + H2O + NAD(+) <=> H(+) + heptan-2-one + NADH + NH4(+)


name: luteolin + UDP-alpha-D-glucuronate <=> H(+) + luteolin 7-O-beta-D-glucuronide + UDP


name: a D-glucoside + NAD(+) => a 3-dehydro-D-glucoside + H(+) + NADH


name: 2 L-tyrosyl-tRNA(Tyr) = cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)


name: 3-phenylpyruvate + S-adenosyl-L-methionine <=> (3S)-2-oxo-3-phenylbutanoate + H(+) + S-adenosyl-L-homocysteine


name: H2O + N-(hexanoyl)sphing-4-enine => hexanoate + sphing-4-enine


name: 2 Na(+)(out) + thymidine(out) = 2 Na(+)(in) + thymidine(in)


name: GUSB tetramer hydrolyses (HA)2 (Homo sapiens)


name: (S)-2-benzylsuccinate + succinyl-CoA <=> (S)-2-benzylsuccinyl-CoA + succinate


name: CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) <=> alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: (3R)-3-[(3R)-3-hydroxydecanoyloxy]decanoate + H(+) + 2 holo-[ACP] => 2 (3R)-hydroxydecanoyl-[ACP] + H2O


name: CoA + H(+) + N-terminal N-hexadecanoyl-L-cysteinyl-[protein] => hexadecanoyl-CoA + N-terminal L-cysteinyl-[protein]


name: mitomycin B + S-adenosyl-L-homocysteine => 6-demethylmitomycin B + S-adenosyl-L-methionine


name: sphinganine 1-phosphate(out) => sphinganine 1-phosphate(in)


name: PRKCI phosphorylates NFE2L2 (Danio rerio)


name: peptide lactyltransferase (ATP-dependent) activity


name: 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one => (E)-caffeoylpyruvate + CO2 + hnu


name: EPHX1 hydrates BaP4,5O to BaP4,5-DHD (Caenorhabditis elegans)


name: DNA nucleases unhook the interstrand crosslink (ICL) (Mus musculus)


name: H(+) + O-5''-beta-D-galactosylqueuosine(34) in tRNA(Tyr) + UDP => queuosine(34) in tRNA(Tyr) + UDP-alpha-D-galactose


name: solasodine + UDP-alpha-D-glucose => H(+) + solasodine 3-beta-D-glucoside + UDP


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Caenorhabditis elegans)


name: maltose + H2O => 2 D-glucose (sucrase-isomaltase) (Rattus norvegicus)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Sus scrofa)


name: PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex (Gallus gallus)


name: PRKCZ recruits RAS in response to estrogen stimulation (Rattus norvegicus)


name: HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)


name: formate + 2 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) = CO2 + reduced coenzyme F420-(gamma-L-Glu)(n)


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Gallus gallus)


name: LRP2 binds extracellular TCN2:RCbl (Mus musculus)


name: CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus (Bos taurus)


name: ferric-chelate reductase (NADH) activity


name: 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3beta-hydroxy-5alpha-androstan-17-one + O2 + reduced [NADPH--hemoprotein reductase]


name: SPHK2 phosphorylates sphingoid (Rattus norvegicus)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Gallus gallus)


name: 4-O-([2-N-acetyl-beta-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP => 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine


name: GRB2:SOS interacts with p-KIT (Xenopus tropicalis)


name: MHC class II protein binding, via antigen binding groove


name: MAT1A multimers transfer Ado from ATP to L-Met (Canis familiaris)


name: all-trans-retinal + O2 + reduced [NADPH--hemoprotein reductase] => all-trans-retinoate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2S)-2-amino-4-deoxychorismate <=> anthranilate + H(+) + pyruvate


name: DAAM1 recruits GTP-bound RHOA (Mus musculus)


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Sus scrofa)


name: T1R2/T1R3 dimer is a sweet taste receptor (Mus musculus)


name: Abortive initiation after formation of the first phosphodiester bond (Canis familiaris)


name: beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA (Canis familiaris)


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Xenopus tropicalis)


name: (2Z,6E)-farnesyl diphosphate <=> (Z)-alpha-bisabolene + diphosphate


name: Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Xenopus tropicalis)


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)


name: H(+)(in) + L-fucose(in) <=> H(+)(out) + L-fucose(out)


name: AMP + 2 H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein]


name: 6-amino-6-deoxyfutalosine + H(+) + H2O => futalosine + NH4(+)


name: 4 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) = 4 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: chloroacetaldehyde + H2O + NADP(+) <=> chloroacetate + 2 H(+) + NADPH


name: Activation of RAS by p-KIT bound SOS1 (Xenopus tropicalis)


name: (S)-4-hydroxymandelonitrile => 4-hydroxybenzaldehyde + hydrogen cyanide


name: a globoside GalGb4Cer + UDP-N-acetyl-alpha-D-glucosamine => a globoside GlcNAc-(beta1->6)-GalGb4Cer + H(+) + UDP


name: G-protein beta/gamma-subunit complex binding


name: (2E)-hexadecenoyl-CoA + H2O2 => hexadecanoyl-CoA + O2


name: Formation of NR-NCOR Corepressor Complex (Caenorhabditis elegans)


name: Retrograde COPI vesicles bind kinesin and microtubules (Caenorhabditis elegans)


name: a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycerol = a triacyl-sn-glycerol + glycerol


name: taurine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoyl-taurine


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Danio rerio)


name: 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 17beta-estradiol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate


name: chylomicron remnant:apoE complex + LDLR => chylomicron remnant:apoE:LDLR complex (Sus scrofa)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Rattus norvegicus)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-adenosine) in mRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine


name: butanoyl-CoA + NADP(+) => (2E)-butenoyl-CoA + H(+) + NADPH


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Caenorhabditis elegans)


name: 13-dihydrodaunorubicin + H(+) + NADPH + O2 = daunorubicin + 2 H2O + NADP(+)


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Caenorhabditis elegans)


name: 4 O2 + ophiobolin F + 4 reduced [NADPH--hemoprotein reductase] <=> 4 H(+) + 6 H2O + ophiobolin C + 4 oxidized [NADPH--hemoprotein reductase]


name: H2O + salicin-6-phosphate = beta-D-glucose 6-phosphate + salicyl alcohol


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Rattus norvegicus)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Xenopus tropicalis)


name: H2O + N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) = acetate + alpha-D-glucosaminyl-[heparan sulfate](n)


name: DCC interaction with SIAH1 (Homo sapiens)


name: 1,2,3-tri-(9Z,12Z,15Z)-octadecatrienoylglycerol + H2O <=> (9Z,12Z,15Z)-octadecatrienoate + 1,3-di-(9Z,12Z,15Z)-octadecatrienoylglycerol + H(+)


name: 1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) <=> a 2-demethylmenaquinol + CO2 + diphosphate


name: (1R,4S)-1-hydroxylimonen-2-one + NADPH + O2 <=> (3S)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+)


name: (9Z,12Z)-octadecadienamide + H2O => (9Z,12Z)-octadecadienoate + NH4(+)


name: 4-aminobutanoate + CO2 => H(+) + L-glutamate


name: PI3K associates with phosphorylated GAB2 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)


name: β1,2-agonists bind ADRB1,2 (Gallus gallus)


name: dTDP-alpha-D-mycaminose + tylactone <=> 5-O-beta-D-mycaminosyltylactone + dTDP + H(+)


name: Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation<br> (Homo sapiens)


name: an N-acylsphing-4-enine + UDP-alpha-D-galactose = H(+) + N-acyl-D-galactosylsphing-4-enine + UDP


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Homo sapiens)


name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Bos taurus)


name: PKC-delta phosphorylates CARD9 (Bos taurus)


name: Phosphorylation of MEK4 by MEKK1 (Sus scrofa)


name: Activation of RAC1 by VAV2/3 (Bos taurus)