name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)


name: L-rhamnofuranose + NAD(+) = H(+) + L-rhamnono-1,4-lactone + NADH


name: PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: H(+) + menadione + NADH <=> menadiol + NAD(+)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: apigenin 7-O-beta-D-glucoside + malonyl-CoA <=> apigenin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: CoA(in) + FAD(out) => CoA(out) + FAD(in)


name: G alpha (q) binds to Trio family RhoGEFs (Homo sapiens)


name: Formation of ORC(1-6) complex (Canis familiaris)


name: SMG6 hydrolyzes mRNA with premature termination codon (Danio rerio)


name: Formation of AT-AC C complex (Sus scrofa)


name: dihydrochelirubine + NAD(+) <=> chelirubine + NADH


name: Dimethyl fumarate modifies Cys191 in GSDMD (Mus musculus)


name: (N(7)-methyl 5'-triphospho-guanosine)-adenosine + a 5'-end phospho-ribonucleoside in mRNA + H(+) => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine-phospho-ribonucleoside in mRNA + H2O


name: IL2RA (CD25) gene expression is stimulated by FOXP3 and inhibited by RUNX1 (Homo sapiens)


name: 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Ubiquitinated geminin is degraded by the proteasome (Homo sapiens)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Bos taurus)


name: CCND1 recruits HDAC4 to RUNX3 (Drosophila melanogaster)


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Drosophila melanogaster)


name: AH2 + chrodrimanin C => 3-hydroxypentacecilide A + A


name: L-threonine + NAD(+) => (2S)-2-amino-3-oxobutanoate + H(+) + NADH


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Homo sapiens)


name: 4-aminobutanoate + ATP + L-histidine <=> ADP + H(+) + L-homocarnosine + phosphate


name: SRC-1 bound to ARRB2 is not activated (Bos taurus)


name: ATR phosphorylates Histone H2A.X at unsynapsed regions (Homo sapiens)


name: 7(1)-hydroxychlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => chlorophyllide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Xenopus tropicalis)


name: Formation of the Spliceosomal P complex and exon ligation (Caenorhabditis elegans)


name: RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoA (Homo sapiens)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Rattus norvegicus)


name: Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Xenopus tropicalis)


name: Exocytosis of platelet alpha granule contents (Saccharomyces cerevisiae)


name: NTHL1 D239Y does not cleave thymine glycol (Tg) (Homo sapiens)


name: STING ubiquitination by TRIM32 or TRIM56 (Danio rerio)


name: CHSY1 transfers GlcA to chondroitin (Xenopus tropicalis)


name: ATP + diphosphate <=> ADP + H(+) + triphosphate


name: AKT phosphorylates FOXO3 downstream of FLT3  (Rattus norvegicus)


name: 3,6-dichlorocatechol + O2 = (2E,4E)-2,5-dichloromuconate + H(+)


name: dihydrobunolol + NADP(+) <=> bunolol + H(+) + NADPH


name: Tyrosine is monoiodinated (Drosophila melanogaster)


name: TGFBR2 KD mutants do not phosphorylate TGFBR1 (Homo sapiens)


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Mus musculus)


name: [protein-PII]-uridylyl-L-tyrosine + H2O => [protein-PII]-L-tyrosine + H(+) + UMP


name: The Ligand:GPCR:G12/13 complex dissociates (Drosophila melanogaster)


name: DNA polymerase epsilon binds at the origin (Mus musculus)


name: 1,2-didecanoyl-sn-glycero-3-phosphate + ADP + H(+) => 1,2-didecanoyl-sn-glycerol + ATP


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-D-GlcNAc + GDP-beta-L-fucose => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc + GDP + H(+)


name: caffeine + H(+) + S-adenosyl-L-homocysteine => 1,7-dimethylxanthine + S-adenosyl-L-methionine


name: H(+) + NADPH + neopatulin = (E)-ascladiol + NADP(+)


name: PINK1 is autophosphorylated (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate = diphosphate + silphinene


name: RHOB binds effectors on endosomes (Sus scrofa)


name: ABCG4 may mediate cholesterol efflux (Canis familiaris)


name: Defective PAH does not hydroxylate L-Phe to L-Tyr (Homo sapiens)


name: FURIN translocates to the plasma membrane (Xenopus tropicalis)


name: 1-acyl-2-(9Z)-enoyl-sn-glycero-3-phospholipid + S-adenosyl-L-methionine = 1-acyl-2-(9-cyclopronane)-acyl-sn-glycero-3-phospholipid + H(+) + S-adenosyl-L-homocysteine


name: ISGylation of protein translation regulator 4EHP (Caenorhabditis elegans)


name: CK2 phosphorylates condensin I subunits (Bos taurus)


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Mus musculus)


name: DDO oxidizes D-Asp to OA (Rattus norvegicus)


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Xenopus tropicalis)


name: Translocation of BBC3 (PUMA) protein to mitochondria (Homo sapiens)


name: glucosyl-limonin + 2 H(+) + UDP => H2O + limonin + UDP-alpha-D-glucose


name: SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Saccharomyces cerevisiae)


name: an N-acyl-L-homoserine lactone + H2O => an N-acyl-L-homoserine + H(+)


name: GRB2:SOS1 complex binds to the active receptor (Drosophila melanogaster)


name: beta-myrcene + O2 + reduced [NADPH--hemoprotein reductase] => (4R)-ipsdienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PER is phosphorylated by DCO (Drosophila melanogaster)


name: 2 H(+) + 2 NADH + 2 O2 + tetracenomycin A2 = H2O + 2 NAD(+) + tetracenomycin C


name: G protein-coupled olfactory receptor activity


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Danio rerio)


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Dictyostelium discoideum)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Rattus norvegicus)


name: 1,6-dihydroxyphenazine + NADPH + O2 = 1,6-dihydroxyphenazine N(5)-oxide + H2O + NADP(+)


name: chloride(out) + D-tryptophan(out) + 2 Na(+)(out) => chloride(in) + D-tryptophan(in) + 2 Na(+)(in)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Rattus norvegicus)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Mus musculus)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Schizosaccharomyces pombe)


name: CHPF,CHSY3 transfer GalNAc to chondroitin (Rattus norvegicus)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Rattus norvegicus)


name: Sequestration of tBID by BCL-2 (Danio rerio)


name: (Z)-3-aminoacrylate + H(+) + H2O => 3-oxopropanoate + NH4(+)


name: dUTP + H2O => dUMP + pyrophosphate (Dictyostelium discoideum)


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Dictyostelium discoideum)


name: Formation of C4b:factor B complex (Gallus gallus)


name: ETA is phosphorylated to PETA by CHK/ETNK (Saccharomyces cerevisiae)


name: H(+) + L-aspartate 4-semialdehyde + NADPH => L-homoserine + NADP(+)


name: DVL1 is bound by the HECT ubiquitin ligase HECW1 (Sus scrofa)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Sus scrofa)


name: 6-carboxy-5,6,7,8-tetrahydropterin + H(+) <=> 7-carboxy-7-deazaguanine + NH4(+)


name: (2E,6E)-farnesyl diphosphate = (+)-valencene + diphosphate


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Drosophila melanogaster)


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Rattus norvegicus)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Gallus gallus)


name: Internalization of receptor bound antigen into clathrin coted vesicles (Gallus gallus)


name: D-mannose + phosphate => D-mannose 6-phosphate + H2O


name: RAF1 mutant complexes phosphorylate MAP2K dimer (Homo sapiens)


name: ITCH binds DTX (Drosophila melanogaster)


name: OGG1beta translocates to mitochondria (Mus musculus)


name: uridine(54/55) in tRNA => pseudouridine(54/55) in tRNA


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Canis familiaris)


name: (2R,3R)-dihydromyricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (2R,3R)-dihydroquercetin + O2 + reduced [NADPH--hemoprotein reductase]


name: (2E)-geranyl diphosphate => (1S,5S)-alpha-pinene + diphosphate


name: CDC14A,B bind MAPK6 (Xenopus tropicalis)


name: H2O + NAD(+) + S-(2-aminoethyl)-L-cysteine => H(+) + NADH + NH4(+) + S-(acetaldehyde)-L-cysteine


name: (3R)-hydroxy-(15Z)-tetracosenoyl-CoA => (2E,15Z)-tetracosadienoyl-CoA + H2O


name: a 1,2-diacyl-sn-glycerol + an N-acylsphinganine-(1D-myo-inositol) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acylsphinganine


name: Autoglucosylation of GYG2 complexed with GYS2-b (Drosophila melanogaster)


name: CNRs bind CNR agonists (Rattus norvegicus)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Bos taurus)


name: 5,6,7,8-tetrahydromethanopterin + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] => 5-methyl-5,6,7,8-tetrahydromethanopterin + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Saccharomyces cerevisiae)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Dictyostelium discoideum)


name: RAB1:GTP recruits GBF1 to the ERGIC (Caenorhabditis elegans)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Schizosaccharomyces pombe)


name: alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + UDP-N-acetyl-alpha-D-glucosamine => alpha-D-Man-(1->3)-[alpha-D-GlcNAc-(1->2)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-D-Man + H(+) + UDP


name: 2-deoxy-D-ribose + ATP = 2-deoxy-D-ribose 5-phosphate + ADP + H(+)


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Sus scrofa)


name: "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters"


name: RNA Pol II initiates transcription from damaged DNA template (Bos taurus)


name: 2-(glutathione-S-yl)-hydroquinone + glutathione => glutathione disulfide + hydroquinone


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Homo sapiens)


name: dihydrochelirubine + H(+) + O2 = chelirubine + H2O2


name: isoheptadecanoyl-coA + NADP(+) => (2E)-15-methylhexadecenoyl-CoA + H(+) + NADPH


name: 2-methylpropanal + hydrogen cyanide => (2S)-2-hydroxy-3-methylbutanenitrile


name: Caspase-mediated cleavage of Rock-1 (Sus scrofa)


name: glycine + octadecanoyl-CoA => CoA + H(+) + N-octadecanoylglycine


name: 3,4,5-trihydroxybenzoate + H(+) = 1,2,3-trihydroxybenzene + CO2


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Sus scrofa)


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: Histone acetyltransferases are recruited to the TFF1 gene (Danio rerio)


name: HTR1A binds HTR1A agonists (Caenorhabditis elegans)


name: CHIT1 hydrolyses CHIT to 3xADGP (Danio rerio)


name: [(3R)-hydroxybutanoate](n) + H2O = (R)-3-hydroxybutanoate + [(3R)-hydroxybutanoate](n-1) + H(+)


name: Association of procollagen type XXII (Mus musculus)


name: H2O + L-alanyl-L-histidine <=> L-alanine + L-histidine


name: PPM1A dephosphorylates nuclear SMAD2/3 (Rattus norvegicus)


name: PLB1 hydrolyses RPALM to atROL (Rattus norvegicus)


name: L-tyrosine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase]


name: B-RAF dissociates from S111/S120 p-SPRY2 (Drosophila melanogaster)


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Sus scrofa)


name: Release of novel PDGFs as latent factors (Sus scrofa)


name: holo-[peptidyl-carrier protein] + L-alanyl-5'-AMP => AMP + H(+) + L-alanyl-[peptidyl-carrier protein]


name: H2O + L-dehydroascorbate = 2,3-dioxo-L-gulonate


name: prostaglandin D2 11-ketoreductase activity


name: trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity


name: L-cysteine + O2 <=> 3-sulfino-L-alanine + H(+)


name: Polymeric PGN binds to PGRP-LCx at the plasma membrane (Drosophila melanogaster)


name: carbon disulfide + H2O = carbonyl sulfide + H(+) + hydrogen sulfide


name: 17beta-hydroxy-5beta-estran-3-one + NADP(+) => 17beta-hydroxyestr-4-en-3-one + H(+) + NADPH


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine


name: ceramide + H2O => stearate + sphingosine [endoplasmic reticulum] (Gallus gallus)


name: 2-(9Z-octadecenoyl)-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate


name: TRPV1 binds TRPV1 agonists (Rattus norvegicus)


name: Activated MET recruits GRB2-1:SOS1 (Mus musculus)


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-cinerolone <=> cinerin I + CoA


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine <=> 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: GDP + H(+) + methyl 8-{[alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc]oxy}nonanoate => GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: p75NTR interacts with the NOGO receptor (Canis familiaris)


name: a ganglioside Ac-O-8-GD1a (d18:1(4E)) => a ganglioside Ac-O-9-GD1a (d18:1(4E))


name: UDP-galactose transmembrane transporter activity


name: a secondary amine + S-adenosyl-L-methionine => a methylated secondary amine + H(+) + S-adenosyl-L-homocysteine


name: SCF betaTrCP1,2 binds p-NFkB p105:TPL2:ABIN2 (Bos taurus)


name: Activated FGFR3 binds FRS3 (Gallus gallus)


name: H2O + taurochenodeoxycholate = chenodeoxycholate + taurine


name: S-adenosyl-L-methionine + trans-aconitate <=> (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine


name: RANBP2 SUMOylates MDM2 with SUMO1 (Xenopus tropicalis)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Homo sapiens)


name: a 1,2-diacylglycerol + a sphingomyelin => 1,2-diacyl-glycero-3-phosphocholine + an N-acylsphing-4-enine


name: NUDT12 hydrolyses NADH to NMNH (Canis familiaris)


name: AH2 + epoxyqueuosine(34) in tRNA <=> A + H2O + queuosine(34) in tRNA


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Saccharomyces cerevisiae)


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Bos taurus)


name: Loading of claspin onto DNA during replication origin firing (Mus musculus)


name: Syk activation leads to SLP-76 activation (Canis familiaris)


name: a uridine in rRNA + S-adenosyl-L-methionine <=> a 2'-O-methyluridine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: proton-transporting ATP synthase activity, rotational mechanism


name: L-kynurenine transmembrane transporter activity


name: 5 H(+) + L-pipecolate + malonyl-CoA + 3 NADPH <=> (1R,8aS)-octahydroindolizin-1-ol + CO2 + CoA + 2 H2O + 3 NADP(+)


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Dictyostelium discoideum)


name: UTP:glucose-1-phosphate uridylyltransferase regulator activity


name: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Bos taurus)


name: Addition of the third nucleotide on the nascent transcript (Saccharomyces cerevisiae)


name: RNA Polymerase II Promoter Opening: First Transition (Caenorhabditis elegans)


name: L-cystine(out) + L-leucine(in) <=> L-cystine(in) + L-leucine(out)


name: TGFBR2 phosphorylates TGFBR1 (Rattus norvegicus)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Gallus gallus)


name: RHOA:GTP:RTKN binds LIN7B (Mus musculus)


name: IL4I1:FAD oxidises L-Phe to kPPV (Plasmodium falciparum)


name: H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) = 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: L-seryl-[EGF-like domain protein] + UDP-alpha-D-glucose => 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: (2E)-octenal + H(+) + pyruvate => (S)-3-acetyloctanal + CO2


name: H(+) + uracil 5-carboxylate = CO2 + uracil


name: GDIs block activation of RHOB (Sus scrofa)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-D-GlcNAc + GDP-beta-L-fucose <=> alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc + GDP + H(+)


name: GSTZ1 isomerizes 4-MAA (Xenopus tropicalis)


name: gibberellin A3 + UDP-alpha-D-glucose <=> gibberellin A3 O-beta-D-glucoside + H(+) + UDP


name: D-ribulose 5-phosphate <=> ribose 5-phosphate (Rattus norvegicus)


name: 7-dehydrocholesterol + 2 H2O + NAD(+) => cholesterol + H(+) + NADH + O2


name: Activated FGFR3 phosphorylates FRS2 (Mus musculus)


name: (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NAD(+) <=> 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADH


name: (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 <=> (5,12,18R)-trihydroxy-(6Z,8E,10E,14Z,16E)-eicosapentaenoate


name: IL1F10 binds IL1RL2 (Xenopus tropicalis)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O


name: SHPRH polyubiquitinates monoubiquitinated PCNA (Schizosaccharomyces pombe)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Canis familiaris)


name: acetate + L-ornithine => H2O + N(2)-acetyl-L-ornithine


name: biphenyl-2,2'-diol + H(+) + NADH + O2 => biphenyl-2,2',3-triol + H2O + NAD(+)


name: P4HB mediates disulfide bond formation in Proinsulin (Sus scrofa)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Sus scrofa)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Mus musculus)


name: Formation of DSIF:NELF:early elongation complex (Rattus norvegicus)


name: (2R,3S)-iso(homo)2citrate + NAD(+) <=> 2-oxoheptanedioate + CO2 + NADH


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] => atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: LAM translocates from the cell wall to the plasma membrane (Homo sapiens)


name: 3-epi-6-deoxocathasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6-deoxotyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Mus musculus)


name: SLC7A2, isoform A (CAT-2A)-mediated uptake of cationic amino acids (Gallus gallus)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) => 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP


name: (R)-S-adenosyl-L-methionine + H2O = adenosine + H(+) + L-methionine


name: tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA (Homo sapiens)


name: acetyl-CoA + N-terminal L-methionyl-L-phenylalanyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-phenylalanyl-[protein]


name: RHOD binds effectors at the Golgi membrane (Homo sapiens)


name: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose => dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate


name: HMG CoA => acetoacetic acid + acetyl CoA (Homo sapiens)


name: Aquaporin-7 passively transports glycerol out of cell (Xenopus tropicalis)


name: Caspase-mediated cleavage of MST3 (Mus musculus)


name: S-adenosyl-L-methionine + theobromine = caffeine + H(+) + S-adenosyl-L-homocysteine


name: (3R)-hydroxy-(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + NADP(+) => (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + H(+) + NADPH


name: Nephrin interacts with Podocin (Drosophila melanogaster)


name: CYP2W1 oxidises INDOL (Drosophila melanogaster)


name: p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Sus scrofa)


name: PP2A dephosphorylates BANF1 (Drosophila melanogaster)


name: 1,3-decanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => decan-1-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: CYPs hydroxylate DHA to 14(R)-HDHA (Canis familiaris)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Danio rerio)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sphinganine <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + sphinganine


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = corticosterone + H2O + 2 oxidized [adrenodoxin]


name: Hydrolysis of phosphatidylcholine (Canis familiaris)


name: ATP + H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out) <=> ADP + H(+) + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) + phosphate


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Canis familiaris)


name: SLC45A3 transports Glc from extracellular region to cytosol (Mus musculus)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Rattus norvegicus)


name: Dephosphorylation of Lck-pY505 by CD45 (Canis familiaris)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + ATP + formate = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate


name: 2 Na(+)(out) + taurochenodeoxycholate(out) <=> 2 Na(+)(in) + taurochenodeoxycholate(in)


name: PIAS1 SUMOylates SATB1 with SUMO2,3 (Mus musculus)


name: 3-(3-hydroxyphenyl)-propanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 3,3',5-trihydroxybibenzyl + 4 CO2 + 4 CoA


name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Sus scrofa)


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Dictyostelium discoideum)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Schizosaccharomyces pombe)


name: (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H(+) + NADH => (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + NAD(+)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Dictyostelium discoideum)


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Danio rerio)


name: USP34 deubiquitinates AXIN1,AXIN2 (Mus musculus)


name: 3-acetamidopropanal + H2O2 + spermidine => H2O + N(1)-acetylspermine + O2


name: 6-phospho-D-gluconate => 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O


name: Dephosphorylation of PAG by SHP2 (Mus musculus)


name: REXO2 hydrolyzes 4-5 nucleotide RNAs to ribonucleotides (Homo sapiens)


name: T2Rs bind bitter-tasting compounds (Homo sapiens)


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Xenopus tropicalis)


name: Association of procollagen type II (Bos taurus)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Bos taurus)


name: Importin-8 imports AGO2:miRNA into the nucleus (Mus musculus)


name: UROD decarboxylates URO3 to COPRO3 (Danio rerio)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Sus scrofa)


name: a ganglioside GD1a + H2O = a ganglioside GM1 + N-acetylneuraminate


name: adenosine 3',5'-bisphosphate + beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H(+) => 3'-phosphoadenylyl sulfate + a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O <=> ADP-alpha-D-ribose 1''-phosphate + H(+)


name: RAC1 GDIs block activation of RAC1 (Dictyostelium discoideum)


name: 2,2-dimethylsuccinate(out) + 3 Na(+)(out) <=> 2,2-dimethylsuccinate(in) + 3 Na(+)(in)


name: FarC-PTP4A2 binds RABGGTB (Canis familiaris)


name: H2O + N-acetyl-alpha-D-glucosamine + NAD(+) <=> 2 H(+) + N-acetyl-D-glucosaminate + NADH


name: TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Homo sapiens)


name: p-PKR dimer localizes to the nucleus (Drosophila melanogaster)


name: H(+) + myricetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP => myricetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose


name: SRC-1 bound to ARRB2 is not activated (Sus scrofa)


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Xenopus tropicalis)


name: P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration


name: N-(4-oxobutylpyrrolinium) ion = 1-formylpyrrolizidine


name: (11Z)-eicosenoyl-CoA + AH2 + O2 <=> (8Z,11Z)-eicosadienoyl-CoA + A + 2 H2O


name: ALAD condenses 2 dALAs to form PBG (Saccharomyces cerevisiae)


name: ADD1:ADD2 binds DMTN (Drosophila melanogaster)


name: Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA (Mus musculus)


name: ALPI dimer hydrolyses phosphate monoesters (Sus scrofa)


name: RNLS:FAD oxidises dh-beta-NAD to NAD+ (Xenopus tropicalis)


name: NAD(+) + prostaglandin A1 => 15-oxo-prostaglandin A1 + H(+) + NADH


name: Orexin 2 receptor can bind orexin-B neuropeptide (Sus scrofa)


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Canis familiaris)


name: B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac (Danio rerio)


name: Rap1 signal termination by Rap1GAPs (Canis familiaris)


name: ABCB1 transports PREDN,PREDL out of hepatic cells (Sus scrofa)


name: thromboxane B2(out) <=> thromboxane B2(in)


name: Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD+PEST domain mutants (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine <=> CoA + H(+) + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Homo sapiens)


name: 3-dehydro-4-O-phospho-L-erythronate + H(+) = CO2 + dihydroxyacetone phosphate


name: 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA


name: reumycin + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + toxoflavin


name: A + arsenite + H2O = AH2 + arsenate + H(+)


name: (20S)-ginsenoside Rd + 2 H2O => (20S)-ginsenoside C-K + 2 D-glucose


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Homo sapiens)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Caenorhabditis elegans)


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Xenopus tropicalis)


name: (2S)-2-acetolactate + H(+) = (R)-acetoin + CO2


name: Nuclear translocation of catalytic domain of Mst3 (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoylglycerol => 1-tetradecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate => 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + H(+)


name: 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate + 5 isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + 5 diphosphate


name: "all-trans-nonaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific]"


name: RAB13 GEFs exchange GTP for GDP on RAB13 (Canis familiaris)


name: 5-hydroxyuridine(34) in tRNA + S-adenosyl-L-methionine <=> 5-methoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-3-hexadecanoyl-sn-glycerol + H(+) => 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H2O


name: Autophosphorylation of PAK1 (Canis familiaris)


name: NTPDase4 hydrolyzes nucleoside diphosphates (Xenopus tropicalis)


name: AKT phosphorylates FOXO transcription factors (Gallus gallus)


name: Association of profilin with monomeric actin (Rattus norvegicus)


name: ACY1:Zn2+ dimer hydrolyses mercapturic acids (Homo sapiens)


name: Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Homo sapiens)


name: ABCAs mediate lipid influx (Dictyostelium discoideum)


name: H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP


name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Sus scrofa)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> (-)-astellatene + diphosphate


name: (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADPH + O2 = (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: butan-2-one + hydrogen cyanide => 2-hydroxy-2-methylbutanenitrile


name: 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA <=> 1-butanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: a menaquinone + 2 H(+)(in) + H2 = a menaquinol + 2 H(+)(out)


name: isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity


name: 3beta,7beta-dihydroxy-5beta-cholan-24-oate + NAD(+) = 3beta-hydroxy-7-oxo-5beta-cholan-24-oate + H(+) + NADH


name: Cytosolic folate export across the plasma membrane (Xenopus tropicalis)


name: Collagen type I binds integrin alpha1beta1, alpha2beta1, alpha10beta1 (Homo sapiens)


name: Caspase-mediated cleavage of Desmoglein 1 (Danio rerio)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Xenopus tropicalis)


name: Translocation of activated BAX to the mitochondria (Mus musculus)


name: Dimerized phospho-IRF3 migrates to the nucleus (Sus scrofa)


name: 1D-myo-inositol 1,2,6-trisphosphate + H2O => 1D-myo-inositol 1,2-bisphosphate + phosphate


name: Sprouty sequesters CBL away from active EGFR (Bos taurus)


name: H2O + NAD(+) + propanal = 2 H(+) + NADH + propanoate


name: PC is hydrolyzed to PA and choline by PLD1/2 (Xenopus tropicalis)


name: glutathione(out) + 3 Na(+)(out) => glutathione(in) + 3 Na(+)(in)


name: HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane (Rattus norvegicus)


name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Mus musculus)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Dictyostelium discoideum)


name: SLP-76 stimulates PLC gamma 2 (Sus scrofa)


name: a beta-D-galactoside + acetyl-CoA <=> a 6-acetyl-beta-D-galactoside + CoA


name: 7alpha,25-dihydroxy-4-cholesten-3-one + H(+) + NADH => 7alpha,25-dihydroxycholesterol + NAD(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: Somatostatin receptors bind somatostatin and cortistatin (Xenopus tropicalis)


name: Surface deployment of platelet dense granule membrane components (Sus scrofa)


name: B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda (Sus scrofa)


name: NAD(+) + resolvin D1 <=> 8-oxoresolvin D1 + H(+) + NADH


name: (R)-glycerate + NADP(+) = 3-hydroxypyruvate + H(+) + NADPH


name: PNPLA4 hydrolyzes TAG (Xenopus tropicalis)


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)


name: 2-methylbutan-1-ol + acetyl-CoA = 2-methylbutyl acetate + CoA


name: 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine => L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Xenopus tropicalis)


name: L-dopa(out) + L-phenylalanine(in) => L-dopa(in) + L-phenylalanine(out)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: diacetyl + H(+) + NADH => (S)-acetoin + NAD(+)


name: SALM2 associate with AMPA and NMDA receptors (Gallus gallus)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Rattus norvegicus)


name: (S)-lactate + L-phenylalanine <=> H2O + N-[(S)-lactoyl]-L-phenylalanine


name: 2'-deoxyadenosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + adenine


name: H(+)(in) + methotrexate(in) = H(+)(out) + methotrexate(out)


name: RAD51B:RAD51C binds single-stranded DNA (Danio rerio)


name: ATP + N(6)-D-ribulosyl-L-lysyl-[protein] => ADP + H(+) + N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein]


name: 2-oxoglutarate + L-arginine <=> 5-guanidino-2-oxopentanoate + L-glutamate


name: DOLK phosphorylates DCHOL to DOLP (Sus scrofa)


name: 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + H(+) => 2-methoxy-6-(all-trans-hexaprenyl)phenol + CO2


name: Reduction of disulphide bonds in MHC II antigens (Canis familiaris)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Mus musculus)


name: 5-formimidoyltetrahydrofolate + glycine <=> (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine


name: 6-oxohexanoate + H2O + NADP(+) => 2-hydroxycyclohexan-1-one + NADPH + O2


name: CoA + O-acyl-(R)-carnitine => (R)-carnitine + an acyl-CoA


name: LDHAL6B reduces PYR to LACT (Mus musculus)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) = 3-(4-hydroxyphenyl)pyruvate + H(+) + NADH


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + hexadecanoyl-CoA => 1-O-hexadecyl-2-acetyl-3-hexadecanoyl-sn-glycerol + CoA


name: Furin cleaves pro-prothrombin to prothrombin (Sus scrofa)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Schizosaccharomyces pombe)


name: ATP + streptomycin <=> 6-O-adenylylstreptomycin + diphosphate


name: H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => (R)-lipoate + L-lysyl-[lipoyl-carrier protein]


name: Formation of the Spliceosomal B complex (Canis familiaris)


name: Multiubiquitination of Nek2A (Rattus norvegicus)


name: 2-acyl LPE is acylated to PE by LPEAT (Rattus norvegicus)


name: 20beta-dihydrocorticosterone + NADP(+) => corticosterone + H(+) + NADPH


name: H2O + triacetate lactone => 3,5-dioxohexanoate + H(+)


name: AMP + diphosphate + L-aspartyl-tRNA(Asp) => ATP + L-aspartate + tRNA(Asp)


name: ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Sus scrofa)


name: 5-HT4, 6 and 7 receptors can bind serotonin (Homo sapiens)


name: 3-[(R)-glyceryl]-diphospho-5'-guanosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin => GMP + H(+) + oxidized 3PG-factor420-0


name: acetyl-CoA + N-terminal L-alanyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[protein]


name: DKK promotes clathrin-dependent internalization of LRP6 (Bos taurus)


name: (2S)-3-sulfolactaldehyde + H2O + NAD(+) => (2S)-3-sulfolactate + 2 H(+) + NADH


name: "With NADH or NADPH as one donor, and the other dehydrogenated"


name: SFTPB,C, PC, PG translocate from lamellar body to extracellular region. (Canis familiaris)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Homo sapiens)


name: Dentin matrix protein 1 binds integrin alphaVbeta3 (Sus scrofa)


name: 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + NADH => (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+)


name: CO2 + gibberellin A19 + H2O + succinate => 2-oxoglutarate + gibberellin A44 + O2


name: (2E,6E,10E)-geranylgeranyl diphosphate = (-)-spiroviolene + diphosphate


name: Collagen type II degradation by MMP15 (Bos taurus)


name: Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) (Xenopus tropicalis)


name: H(+)(out) + L-valine(in) = H(+)(in) + L-valine(out)


name: biochanin A 7-O-beta-D-glucoside + H(+) + UDP => biochanin A + UDP-alpha-D-glucose


name: goralatide + H2O = L-lysyl-L-proline + N-acetyl-L-seryl-L-aspartate


name: TASP1 cleaves KMT2A (Drosophila melanogaster)


name: rifamycin SV ortho-naphthoquinone carboxamide = rifamycin SV para-naphthoquinone carboxamide


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Danio rerio)


name: (20S)-ginsenoside Rb2 + 2 H2O <=> (20S)-ginsenoside C-Y + 2 D-glucose


name: chlorophyllide a + NADP(+) => 3,8-divinyl chlorophyllide a + H(+) + NADPH


name: NID1 degradation by MMP14, MMP15 (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexanoate => 1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + H2O


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Canis familiaris)


name: 27-hydroxycholesterol is 7alpha-hydroxylated (Rattus norvegicus)


name: hexadecane-1,2-diol + 2 hexadecanoyl-CoA => 1,2-O,O-dihexadecanoyl-1,2-hexadecanediol + 2 CoA


name: 8-oxo-dGTP + 2 H2O = 8-oxo-dGMP + 2 H(+) + 2 phosphate


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(in) + ATP + H2O


name: CANX dissociates from IL12A:EBI3 (Sus scrofa)


name: Expression of MYOCD in cardiogenesis (Homo sapiens)


name: 2-oxohexanoate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminohexanoate


name: MATEs mediate extrusion of xenobiotics (Saccharomyces cerevisiae)


name: (R)-1-phenylethylamine + H2O + NAD(+) => acetophenone + H(+) + NADH + NH4(+)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-3-phosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: acetyl-CoA + butanoate => acetate + butanoyl-CoA


name: USP9X binds Ub:PEX5L (Drosophila melanogaster)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Drosophila melanogaster)


name: CDK1 phosphorylates VCPIP1 (Gallus gallus)


name: 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + dimethylallyl diphosphate <=> 2,4,7,9-tetrahydroxy-6-methyl-8-(2-methylbut-3-en-2-yl)-1-oxo-1H-phenalen-3-ol + diphosphate


name: 7,8-dihydroneopterin + phosphate => 7,8-dihydroneopterin 3'-phosphate + H2O


name: a long-chain (3R)-hydroxyacyl-CoA <=> a long-chain (2E)-enoyl-CoA + H2O


name: dTDP-N-hydroxy-beta-L-evernosamine + H2O + NADP(+) => dTDP-beta-L-evernosamine + NADPH + O2


name: Association of procollagen type XXI (Homo sapiens)


name: Phosphorylation of ZAP-70 by Lck (Sus scrofa)


name: Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)


name: mandelonitrile + vicianose => (R)-vicianin + H2O


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: avenanthramide B + H(+) + S-adenosyl-L-homocysteine => avenanthramide C + S-adenosyl-L-methionine


name: N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-homocysteine


name: Glucosylation of collagen propeptide hydroxylysines (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine => (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: L-cysteinyl-[protein] + octadecanoyl-CoA <=> CoA + S-octadecanoyl-L-cysteinyl-[protein]


name: 4-methyl-2-oxopentanoate + H(+) + NADH + NH4(+) => H2O + L-leucine + NAD(+)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(36-hydroxyhexatriacontadienoyl)-sphing-4-enine => a diacylglycerol + an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontadienoyl)-sphing-4-enine


name: RXRA:PPARD binds FABP5:atRA (Homo sapiens)


name: 3-oxohexacosanoyl-CoA + H(+) + NADPH = (3R)-hydroxyhexacosanoyl-CoA + NADP(+)


name: [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity


name: PSAP(195-273) forms a dimer (Rattus norvegicus)


name: (2S,3S)-3-methylphenylalanine + 2-oxoglutarate <=> (3S)-2-oxo-3-phenylbutanoate + L-glutamate


name: SGMS2 transfers phosphocholine onto ceramide (Plasmodium falciparum)


name: (-)-alpha-cedrene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: 3'-phosphoadenylyl sulfate + cholesterol <=> adenosine 3',5'-bisphosphate + cholesterol sulfate + H(+)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Saccharomyces cerevisiae)


name: gypsogenin + O2 + reduced [NADPH--hemoprotein reductase] <=> gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetyl-CoA + hexadecanoyl-CoA = 3-oxooctadecanoyl-CoA + CoA


name: (R)-reticuline + S-adenosyl-L-methionine = (R)-tembetarine + H(+) + S-adenosyl-L-homocysteine


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Drosophila melanogaster)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Canis familiaris)


name: FADH2 + O2 + phenol = catechol + FAD + H(+) + H2O


name: 2 H2O + L-cystine-bis-glycine => 2 glycine + L-cystine


name: HSF1-mediated gene expression (Caenorhabditis elegans)


name: glycine betaine(out) + H(+)(out) => glycine betaine(in) + H(+)(in)


name: Autocatalytic activation of MMP7 (Xenopus tropicalis)


name: SCF(SKP2) polyubiquitinates RUNX2 (Canis familiaris)


name: EDTA + 2 FMNH2 + 2 O2 => ethylenediaminediacetate + 2 FMN + 2 glyoxylate + 3 H(+) + 2 H2O


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 20S,25-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Xenopus tropicalis)


name: (S)-2-hydroxyglutarate + O2 <=> 2-oxoglutarate + H2O2


name: Dissociation of the P2Y purinoceptor 12:Gi complex (Canis familiaris)


name: GDIs block activation of RHOG (Drosophila melanogaster)


name: deoxycholate + glycine => glycodeoxycholate + H2O


name: Degradation of multiubiquitinated Securin (Canis familiaris)


name: PLK1 binds phosphorylated condensin II complex (Sus scrofa)


name: ATP + glutathione(in) + glycocholate(in) + H2O <=> ADP + glutathione(out) + glycocholate(out) + H(+) + phosphate


name: NUDT2 hydrolyses GP4G to GTP, GMP (Rattus norvegicus)


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Sus scrofa)


name: a (3S)-3-hydroxyacyl-CoA + NAD(+) <=> a 3-oxoacyl-CoA + H(+) + NADH


name: H(+) + prephenate <=> 3-phenylpyruvate + CO2 + H2O


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate) + H2O => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Bos taurus)


name: ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Sus scrofa)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(N-hexadecanoyl)-serine + H2O => (9Z)-octadecenoate + 1-octadecanoyl-2-hydroxy-sn-glycero-3-phospho-(N-hexadecanoyl)-serine + H(+)


name: TRIM25 binds monoUb:164-PCNA (Homo sapiens)


name: AH2 + asnovolin J + O2 <=> A + asnovolin A + H2O


name: [(1->3)-alpha-D-glucosyl](n+1) + H(+) + UDP => [(1->3)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose


name: Activated glucocorticoid receptor represses NPAS4 gene transcription (Homo sapiens)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Canis familiaris)


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + NADPH => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+)


name: SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to SMAD3 (Homo sapiens)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Rattus norvegicus)


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Caenorhabditis elegans)


name: p-PKR dimer phosphorylates PTPN2 (Homo sapiens)


name: acetylacetone + O2 <=> acetate + H(+) + methylglyoxal


name: a 2,3-diacyl-sn-glycerol + H2O <=> a 2-acylglycerol + a fatty acid + H(+)


name: myo-inositol + S-adenosyl-L-methionine <=> 1D-4-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: 3-oxooctadecanoyl-CoA + H(+) + NADPH <=> (3R)-hydroxyoctadecanoyl-CoA + NADP(+)


name: TRAPPC complexes exchange GTP for GDP on RAB1 (Rattus norvegicus)


name: cyclohexanecarbaldehyde + hydrogen cyanide => (2S)-2-cyclohexyl-2-hydroxyacetonitrile


name: STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Xenopus tropicalis)


name: (9Z,12Z)-octadecadienoyl-CoA + 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol <=> 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA


name: 2 AH2 + echinenone + 2 O2 = 2 A + canthaxanthin + 3 H2O


name: bisphenol A + H(+) + NADH + O2 => 2,2-bis(4-hydroxyphenyl)-1-propanol + H2O + NAD(+)


name: Sequestration of tBID by BCL-2 (Canis familiaris)


name: POLZ elongates POLI-incorporated dNMP (Saccharomyces cerevisiae)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Xenopus tropicalis)


name: TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Mus musculus)


name: 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine <=> 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine


name: UBP43 binds IFNAR2 and prevents JAK1 interaction (Homo sapiens)


name: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + H(+) + S-adenosyl-L-homocysteine


name: (2R,3S,4S)-3,4-leucopelargonidin + 2-oxoglutarate + O2 = (4S)-2,3-dehydroleucopelargonidin + CO2 + H(+) + H2O + succinate


name: Formation of RAD50:MRE11 complex (Mus musculus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Danio rerio)


name: H2O + P(1),P(3)-bis(5'-adenosyl) triphosphate => ADP + AMP + 2 H(+)


name: 1,4-benzoquinone + H(+) + NADH = hydroquinone + NAD(+)


name: 4-phospho-D-erythronate + NAD(+) <=> 3-dehydro-4-O-phospho-D-erythronate + H(+) + NADH


name: 4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA + H(+)


name: MAPK6 is degraded by the 26S proteasome (Rattus norvegicus)


name: CFTR transits to the plasma membrane (Sus scrofa)


name: 25-hydroxyvitamin D2 + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 1alpha,25-dihydroxyvitamin D2 + H2O + 2 oxidized [adrenodoxin]


name: 4-hydroxybenzoate + ATP + H(+) = 4-hydroxybenzoyl-5'-AMP + diphosphate


name: 1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP


name: Digestion of triacylglycerols by extracellular PTL:colipase (Rattus norvegicus)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA (Danio rerio)


name: 6-O-methyl-N-deacetylipecoside + H2O <=> 6-O-methyl-N-deacetylipecoside aglycone + D-glucose


name: 1,5-anhydro-D-fructose + H(+) + NADPH => 1,5-anhydro-D-glucitol + NADP(+)


name: MBTPS2 (S2P) cleaves CREB3L3 (Gallus gallus)


name: NR1H2,3 binds the APOC4 gene (Homo sapiens)


name: ADP + thiamine diphosphate = AMP + thiamine triphosphate


name: QPRT transfers PRIB to QUIN to form NAMN (Rattus norvegicus)


name: H2O + NAD(+) + propan-2-ol => H(+) + NADH + O2 + propane


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Rattus norvegicus)


name: an N-(2-hydroxyacyl)-beta-D-galactosyl-sphinganine + H(+) + UDP => an N-(2-hydroxyacyl)-sphinganine + UDP-alpha-D-galactose


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Bos taurus)


name: LIPT2 transfers octanoyl group to GCSH (Homo sapiens)


name: geranylgeranyl diphosphate <=> diphosphate + fusicocca-2,10(14)-diene


name: Growth hormone forms dimers and oligomers (Sus scrofa)


name: all-trans-retinyl hexadecanoate + H2O <=> 11-cis-retinol + H(+) + hexadecanoate


name: an all-trans-retinyl ester + H2O = a fatty acid + all-trans-retinol + H(+)


name: Auto-ubiquitination of TRAF6 (Sus scrofa)


name: L-serine + NADP(+) <=> 2-aminomalonate semialdehyde + H(+) + NADPH


name: a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + H(+) + UDP => a flavonol 3-O-beta-D-glucoside + UDP-beta-L-rhamnose


name: L-ascorbate(out) + monodehydro-L-ascorbate radical(in) => L-ascorbate(in) + monodehydro-L-ascorbate radical(out)


name: TBC1D25 (OATL1) binds ATG8 homologues (Sus scrofa)


name: odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Gallus gallus)


name: a menaquinol + H(+) + S-adenosyl-L-homocysteine => a 2-demethylmenaquinol + S-adenosyl-L-methionine


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + veratrole <=> 3-methoxyphenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: 16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 16-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 => A + H2O + prostaglandin H2


name: 1,6-didemethyltoxoflavin + S-adenosyl-L-methionine => H(+) + reumycin + S-adenosyl-L-homocysteine


name: ATP + GTP <=> diphosphate + pppA(2'-5')pG


name: SERPINB13 binds cathepsin L (Gallus gallus)


name: H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphate <=> N-acyl-15-methylhexadecasphing-4-enine + phosphate


name: ORC6 translocates to the nucleus (Canis familiaris)


name: 15-cis-phytoene + plastoquinone-9 => 15,9'-di-cis-phytofluene + plastoquinol-9


name: ACAT1 tetramer acetylates IDH2 dimer (Xenopus tropicalis)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Rattus norvegicus)


name: ATP + H2O + L-alanyl-L-aspartate(out) => ADP + H(+) + L-alanyl-L-aspartate(in) + phosphate


name: 5-hydroxyxanthotoxin + S-adenosyl-L-methionine <=> isopimpinellin + S-adenosyl-L-homocysteine


name: cyclo(L-leucyl-L-leucyl) + 4 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin] + pulcherriminic acid


name: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Rattus norvegicus)


name: RHOG GAPs stimulate RHOG GTPase activity (Caenorhabditis elegans)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Rattus norvegicus)


name: ALDH3A2-2 oxidizes pristanal to pristanate (Bos taurus)


name: plasmodiophorol B => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: CBL ubiquitinates FRS2 and FGFR4 (Rattus norvegicus)


name: gamma-hexachlorocyclohexane <=> (3R,4S,5S,6R)-pentachlorocyclohexene + chloride + H(+)


name: 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate => H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Caenorhabditis elegans)


name: HPO dimer binds to RASSF (Drosophila melanogaster)


name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Rattus norvegicus)


name: carnosine(out) + 2 H(+)(out) = carnosine(in) + 2 H(+)(in)


name: fumarate(in) + L-aspartate(out) => fumarate(out) + L-aspartate(in)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-4-deoxy-4-formamido-beta-L-arabinose <=> 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + UDP


name: ATP + H2O + L-cystine(out) => ADP + H(+) + L-cystine(in) + phosphate


name: Recognition and Binding of Core Promoter Elements by TFIID (Xenopus tropicalis)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Xenopus tropicalis)


name: H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-L-phenylalanine = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + L-phenylalanine


name: STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Sus scrofa)


name: TCN2 binds RCbl in the circulation (Sus scrofa)


name: ZIP8 mediates zinc influx into cells (Caenorhabditis elegans)


name: Active p38 MAPK phosphorylates MAPKAPK5 (Mus musculus)


name: NAT1,2 acetylate APAP-Cys to APAP-Mer (Homo sapiens)


name: 2',4,4',6'-tetrahydroxychalcone + UDP-alpha-D-glucose <=> 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H(+) + UDP


name: 2-oxoglutarate(out) + 2-oxoheptanedioate(in) => 2-oxoglutarate(in) + 2-oxoheptanedioate(out)


name: chloride(out) + D-methionine(out) + 2 Na(+)(out) <=> chloride(in) + D-methionine(in) + 2 Na(+)(in)


name: a 3-oxo acid + succinyl-CoA => a 3-oxoacyl-CoA + succinate


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Rattus norvegicus)


name: HMGCR dimer reduces bHMG-CoA to MVA (Rattus norvegicus)


name: diphosphate + N(6)-(dimethylallyl)adenosine 5'-triphosphate => ATP + dimethylallyl diphosphate


name: an ultra-long-chain di-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxo-ultra-long-chain di-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: "meromycolic acid 3-oxoacyl-(acyl carrier protein) synthase II"


name: ATM phosphorylates DYRK2 (Canis familiaris)


name: SIRT6 deacetylates RBBP8 (Xenopus tropicalis)


name: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + N-acetyl-D-glucosamine


name: Transfer of SUMO2 from E1 to UBE2I (UBC9) (Homo sapiens)


name: PLEKHA3,8 bind PI4P, ARF1 (Homo sapiens)


name: ISGylation of host proteins (Bos taurus)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Danio rerio)


name: POLI incorporates dNMP opposite to damaged DNA base (Gallus gallus)


name: ATP + D-alanine + H(+) = D-alanyl-5'-AMP + diphosphate


name: L-ribulose 5-phosphate <=> L-xylulose 5-phosphate


name: dehydroabietadienal + H2O + NADP(+) => dehydroabietate + 2 H(+) + NADPH


name: P4HB:4-Hyp collagen propeptides dissociates (Bos taurus)


name: a D-galactosylceramide + H2O = an N-acyl-sphingoid base + D-galactose


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Drosophila melanogaster)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA


name: Oxidative damage to the AP site (Drosophila melanogaster)


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Homo sapiens)


name: UCHL5, USP15 deubiquitinate TGFBR1 (Homo sapiens)


name: Cleavage of collagen VII NC2 region by BMP1 (Caenorhabditis elegans)


name: RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Sus scrofa)


name: Mcm2-7 is phosphorylated by DDK (Sus scrofa)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Canis familiaris)


name: an aldopyranose + NADP(+) = aldono-1,5-lactone + H(+) + NADPH


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Xenopus tropicalis)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Drosophila melanogaster)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Bos taurus)


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Homo sapiens)


name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Homo sapiens)


name: 2,3-dihydroxybenzoate + ATP + H(+) => 2,3-dihydroxybenzoyl-5'-AMP + diphosphate


name: 2-oxoglutarate + decanoyl-CoA + O2 => 2-hydroxydecanoyl-CoA + CO2 + succinate


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Caenorhabditis elegans)


name: A + 2 H2O + N-acyl-15-methylhexadecasphing-4-enine => AH2 + N-acyl-15-methylhexadecasphinganine + O2


name: noranthrone + O2 => H2O + norsolorinic acid


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Danio rerio)


name: a 2'-deoxyguanosine in DNA + methylglyoxal => an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Canis familiaris)


name: butanoate + 2 H(+) + NADH => butanal + H2O + NAD(+)


name: MAOA inhibitors bind MAOA:FAD (Gallus gallus)


name: N,N-dimethylglycine(out) + Na(+)(out) = N,N-dimethylglycine(in) + Na(+)(in)


name: [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B <=> yaequinolone D


name: Nociceptin receptor binds to nociceptin (Mus musculus)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation  (Canis familiaris)


name: Engulfment of particulate antigen into phagocytic vesicle (Bos taurus)


name: p-S MAPK6,4 binds MAPKAPK5 (Gallus gallus)


name: IL35 binds IL27RA:IL12RB2 receptor (Bos taurus)


name: (9Z)-octadecenoyl-CoA + H2O <=> (9Z)-octadecenoate + CoA + H(+)


name: adenosine 3',5'-bisphosphate + decanoyl-4'-phosphopantetheine + 2 H(+) => decanoyl-CoA + H2O


name: Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV (Canis familiaris)


name: a 5'-end diphospho-guanosine in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein] = a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + L-lysyl-[protein]


name: H(+) + H2O + N-isopropylammelide = cyanurate + isopropylamine


name: (3S)-hydroxytetradecanedioyl-CoA + NAD(+) => 3-oxotetradecanedioyl-CoA + H(+) + NADH


name: guanosine(748) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylguanosine(748) in 23S rRNA + S-adenosyl-L-homocysteine


name: CPTP transports C1P from plasma membrane to Golgi membrane (Mus musculus)


name: 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + 10-hydroxyoctadecanoate + H(+) => 1-hexadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O


name: ROS oxidize thioredoxin and activate MAP3K5 (Mus musculus)


name: SALMs1-3 bind each other in cis interactions (Bos taurus)


name: SUMOylation of TOPORS with SUMO1 (Sus scrofa)


name: (E)-4-coumaroyl-CoA + 5-hydroxyanthranilate = avenanthramide A + CoA


name: Binding of cAMP to HCN channels (Drosophila melanogaster)


name: 3,4-dihydroxybenzaldehyde + AH2 + tyramine => A + H2O + norbelladine


name: 3CLp dimer binds α-Ketoamides (Homo sapiens)


name: factor VIIIa associates with cell membrane (Rattus norvegicus)


name: a 1,2-diacylglycerol + H2O => a 1-acylglycerol + a fatty acid + H(+)


name: hydrogen sulfide + O-succinyl-L-homoserine = L-homocysteine + succinate


name: Co-precorrin-7 + S-adenosyl-L-methionine = Co-precorrin-8X + H(+) + S-adenosyl-L-homocysteine


name: p-PKR dimer phosphorylates PTPN2 (Drosophila melanogaster)


name: NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex (Rattus norvegicus)


name: Recruitment of POLB to oxidatively damaged AP site (Homo sapiens)


name: H2O + pyrazinamide = NH4(+) + pyrazine-2-carboxylate


name: cholesteryl hexadecanoate + CoA => cholesterol + hexadecanoyl-CoA


name: membrane potential driven uniporter activity


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Bos taurus)


name: H(+) + hexadecanoyl-CoA + L-serine <=> 3-oxosphinganine + CO2 + CoA


name: (indol-3-yl)acetate + H(+) + NADH + O2 <=> 2-hydroxy-(1H-indol-3-yl)acetate + H2O + NAD(+)


name: Expression of MESP2 in presomitic mesoderm (Homo sapiens)


name: PRMT1 arginine-methylates RUNX1 (Canis familiaris)


name: STAB2:ligand is endocytosed (Homo sapiens)


name: PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Rattus norvegicus)


name: CARM1 methylates arginine-27 of histone H3 (H3R26) (Bos taurus)


name: PTGS1 dimer binds PTGS1 Inhibitors (Sus scrofa)


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Saccharomyces cerevisiae)


name: Defective GALK1 does not phosphorylate Gal (Homo sapiens)


name: Formation of ADAR2  homodimer (Homo sapiens)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Sus scrofa)


name: an (S)-cis-N-methyl-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-homocysteine => an (S)-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-methionine


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Sus scrofa)


name: Syk/Lck phosphorylate LAT (Rattus norvegicus)


name: (2S)-2-hydroxy-3-methylbutanenitrile => 2-methylpropanal + hydrogen cyanide


name: AMP + diphosphate + H(+) + L-asparagine + L-glutamate => ATP + H2O + L-aspartate + L-glutamine


name: CFTR transits to the plasma membrane (Homo sapiens)


name: Lsm1-7 Complex binds deadenylated mRNA (Plasmodium falciparum)


name: H2O + paraoxon <=> 4-nitrophenol + diethylphosphate + 2 H(+)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ATP + H2O => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ADP + H(+) + phosphate


name: CTLH E3 ligase ubiquitinates PKM-1 (Danio rerio)


name: ATP + H2O + urea(out) => ADP + H(+) + phosphate + urea(in)


name: inosine(out) + 2 Na(+)(out) => inosine(in) + 2 Na(+)(in)


name: HMGCR dimer binds statins (Homo sapiens)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers. (Homo sapiens)


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Dictyostelium discoideum)


name: L-alanine(in) + L-phenylalanine(out) <=> L-alanine(out) + L-phenylalanine(in)


name: malonate(out) + succinate(in) => malonate(in) + succinate(out)


name: CHRM1,3,5 bind acetylcholine (Rattus norvegicus)


name: SUMOylation of PIAS4 with SUMO1 (Sus scrofa)


name: (2E)-docosenoyl-CoA + H2O => (3S)-hydroxydocosanoyl-CoA


name: LYZ binds bacterial peptidoglycan (Danio rerio)


name: ATP + N(4)-acetylcytidine <=> ADP + H(+) + N(4)-acetylcytidine 5'-phosphate


name: PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Homo sapiens)


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)


name: ACER3 hydrolyzes phytoceramide (Canis familiaris)


name: 2 AH2 + all-trans-zeaxanthin + 2 O2 <=> 2 A + all-trans-adonixanthin + 3 H2O


name: ADP + arsenite(out) + H(+) + phosphate => arsenite(in) + ATP + H2O


name: diacetyl + H(+) + NADPH => acetoin + NADP(+)


name: Melanin-concentrating hormone receptors bind MCH (Mus musculus)


name: PP2A methylation by LCMT1 (Rattus norvegicus)


name: PLK1 phosphorylates OPTN (Canis familiaris)


name: SLC25A11 exchanges 2-OG and MAL (Drosophila melanogaster)


name: RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc (Rattus norvegicus)


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Canis familiaris)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Sus scrofa)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Schizosaccharomyces pombe)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + choline + H(+) => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O


name: BTN2A2 binds T cell surface (Canis familiaris)


name: glutarate(in) + xanthurenate(out) => glutarate(out) + xanthurenate(in)


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Dictyostelium discoideum)


name: NRG2-activated ERBB4 binds GABA receptors through GABRA1 (Homo sapiens)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Sus scrofa)


name: glycoursodeoxycholate + NADP(+) => 7-oxoglycolithocholate + H(+) + NADPH


name: (E)-2-benzylidenesuccinyl-CoA + H2O => (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA


name: 3-maleylpyruvate + H2O = H(+) + maleate + pyruvate


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Saccharomyces cerevisiae)


name: AKT1 phosphorylates eNOS (Plasmodium falciparum)


name: 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: chloride(out) + dopamine(out) + 2 Na(+)(out) => chloride(in) + dopamine(in) + 2 Na(+)(in)


name: Factor D cleaves C3(H2O)-bound Factor B (Homo sapiens)


name: acetoin + NADP(+) = diacetyl + H(+) + NADPH


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Homo sapiens)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Sus scrofa)


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Sus scrofa)


name: 9-riburonosyladenine + H(+) + H2O2 => 5'-dehydroadenosine + H2O + O2


name: A + ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] = AH2 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + serpentine


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Mus musculus)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Gallus gallus)


name: K63polyUb-TAK1 autophosphorylates (Gallus gallus)


name: De novo formation of eIF2:GTP (Schizosaccharomyces pombe)


name: H2O + taurochenodeoxycholate => chenodeoxycholate + taurine


name: decanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-decenoyl-CoA + reduced [electron-transfer flavoprotein]


name: Formation of the MLL3 complex (Rattus norvegicus)


name: 6-deoxy-6-sulfo-D-fructose + ATP <=> 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H(+)


name: Expression of GATA6 in definitive endoderm (Homo sapiens)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Mus musculus)


name: Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA (Homo sapiens)


name: MADD exchanges GTP for GDP on RAB27 (Mus musculus)


name: 4 A + all-trans-4,4'-diapolycopene-4,4'-dial + 6 H2O => 4 AH2 + all-trans-4,4'-diapolycopene + 4 O2


name: (E)-sinapate + ATP + H(+) = (E)-sinapoyl-AMP + diphosphate


name: acetyl-CoA + 4 H(+) + 6 malonyl-CoA <=> 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + 6 CO2 + 7 CoA + H2O


name: ST translocates from cytosol to mitochondrial matrix of hepatocytes (Homo sapiens)


name: G alpha (q) in G (q):RGS complex is inactivated (Drosophila melanogaster)


name: (7R)-7-(5-carboxy-5-oxopentanamido)deacetylcephalosporanate + D-glutamate => 2-oxoglutarate + cephalosporin C


name: Two NPFF receptors can bind neuropeptide FF (Rattus norvegicus)


name: isocitrate dehydrogenase (NAD+) activity


name: AP-1 transcription factor binds IL1A promoter (Homo sapiens)


name: DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA (Homo sapiens)


name: CDC42 and PIP2 bind WASL, activating it (Gallus gallus)


name: 2-dehydro-L-idonate + H(+) + NADPH => L-idonate + NADP(+)


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Canis familiaris)


name: tBID binds to inactive BAK protein (Bos taurus)


name: coenzyme B + coenzyme M + methanophenazine => coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine


name: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) => 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Caenorhabditis elegans)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Caenorhabditis elegans)


name: 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase] => cholesta-5,7-dien-3beta,25-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FADH2-C4alpha-hydroperoxide + NADPH + rifampicin <=> FADH2 + H(+) + H2O + NADP(+) + rifampicin hemiaminal


name: 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: EP300 acetylates histone H2A, H2B, H3, H4 (Drosophila melanogaster)


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Mus musculus)


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Mus musculus)


name: acetyl-CoA + CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate <=> CMP-5'-(N-acetyl-N-hydroxy-3-aminopropyl)phosphonate + CoA


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 5-hydroxy-L-tryptophan => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2


name: 2 (S)-lactate(in) + prostaglandin E3(out) => 2 (S)-lactate(out) + prostaglandin E3(in)


name: 2-oxoglutarate + a (3R)-3-{[carboxy(hydroxy)methyl]amino}fatty acid + O2 => a (3R)-3-isocyanyl-fatty acid + 2 CO2 + 2 H2O + succinate


name: deacetylation of O-acetylserine and sulfhydrylation using CysK2 (Mycobacterium tuberculosis)


name: USP9X binds Ub:PEX5L (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Canis familiaris)


name: Autophosphorylation of insulin receptor (Xenopus tropicalis)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Drosophila melanogaster)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Drosophila melanogaster)


name: 2 ATP + 2 indole-3-pyruvate <=> 2 AMP + didemethylasterriquinone D + 2 diphosphate + H(+)


name: prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer (Canis familiaris)


name: ADP + phosphate + succinyl-CoA => ATP + CoA + succinate


name: RIP3 binds TRIF to mediate necroptosis (Rattus norvegicus)


name: ULK complex translocates to the ER (Mus musculus)


name: butanoyl-CoA + NADP(+) = (2E)-butenoyl-CoA + H(+) + NADPH


name: 3-(imidazol-5-yl)pyruvate + H(+) + NADPH => (S)-3-(imidazol-5-yl)lactate + NADP(+)


name: Unknown enzyme hydroxylates DMPhOH (Homo sapiens)


name: FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein (Homo sapiens)


name: PDGF-AA clevage by Furin (Gallus gallus)


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Xenopus tropicalis)


name: ent-kaur-16-en-19-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> ent-kaur-16-en-19-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: shikimate transmembrane transporter activity


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Bos taurus)


name: p-Y-STATs translocate to nucleus (Gallus gallus)


name: AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40) (Homo sapiens)


name: ATP + dihydroxyacetone <=> ADP + dihydroxyacetone phosphate + H(+)


name: TULP3 is required for GPR161 localization in the cilium (Homo sapiens)


name: Recruitment of Spike trimer to assembling virion (Homo sapiens)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Drosophila melanogaster)


name: RFC dissociates after sliding clamp formation (Saccharomyces cerevisiae)


name: 3'-phosphoadenylyl sulfate + thyroxine <=> adenosine 3',5'-bisphosphate + H(+) + thyroxine sulfate


name: H2O + norspermine + O2 = 3-aminopropanal + H2O2 + norspermidine


name: ORC5 binds ORC2:ORC3 (Drosophila melanogaster)


name: Activation of RAC1 by VAV2/3 (Gallus gallus)


name: S-adenosyl-L-methionine + uridine(2843) in 25S rRNA => H(+) + N(3)-methyluridine(2843) in 25S rRNA + S-adenosyl-L-homocysteine


name: RUNX2 translocates to the nucleus (Homo sapiens)


name: Extracellular processing of novel PDGFs (Rattus norvegicus)


name: MASTL (GWL) phosphorylates ARPP19 (Gallus gallus)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Rattus norvegicus)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Rattus norvegicus)


name: ALDH4A1 oxidises L-GluSS to Glu (Homo sapiens)


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Bos taurus)


name: 4-hydroxybenzoate + all-trans-heptaprenyl diphosphate => 4-hydroxy-3-all-trans-heptaprenylbenzoate + diphosphate


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+) => (2R)-3-phosphoglycerate + GDP-D-glucose


name: PDE12 cleaves 2'-5' oligoadenylates  (Mus musculus)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Bos taurus)


name: Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)


name: EPH receptors autophosphorylate (Rattus norvegicus)


name: PPP1CC dephosphorylates PLK1 (Xenopus tropicalis)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Xenopus tropicalis)


name: PGE2 is converted to PGF2a by CBR1 (Rattus norvegicus)


name: FOXM1 stimulates CCNB1 transcription (Homo sapiens)


name: SH2 domain of Src binds to the active receptor (Sus scrofa)


name: AKT phosphorylates FOXO1A (Mus musculus)


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides


name: 1D-myo-inositol 3,4,6-trisphosphate + ATP <=> 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H(+)


name: IER3 recruits MAPKs to PP2A-B56-beta,gamma (Danio rerio)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Homo sapiens)


name: F2R:ARRB2 binds MAPKs, SRC-1 (Homo sapiens)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Xenopus tropicalis)


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine => [DsrC protein]-disulfide + H(+) + hydrogen sulfide


name: 2 (E)-sinapoyl-CoA + spermidine = 2 CoA + 2 H(+) + N(1),N(8)-bis[(E)-sinapoyl]-spermidine


name: (2E)-butenoyl-[ACP] + AMP + H(+) => (2E)-but-2-enoyl-AMP + holo-[ACP]


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Gallus gallus)


name: Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 (Danio rerio)


name: (E)-4-hexen-3-one + H(+) + NADPH => hexan-3-one + NADP(+)


name: H2O + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2) <=> beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: 2-dehydro-D-gluconate + NADP(+) = 2,5-didehydro-D-gluconate + H(+) + NADPH


name: Pol II elongation complex moves on the template as transcript elongates (Canis familiaris)


name: glutathione S,S-dioxide + H(+) => O2 + S-sulfanylglutathione


name: ADA catalyzes the deamination of (deoxy)adenosine (Danio rerio)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Mus musculus)


name: Neurolysin degrades neurotensin (Sus scrofa)


name: pancreatic polypeptide receptor activity


name: fecosterol + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + zymosterol


name: Defective MMADHC does not bind MMACHC:B12r (Homo sapiens)


name: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide


name: Cannabinoid receptors can bind cannabinoids (Canis familiaris)


name: Gbeta:gamma activation of PLC beta (Homo sapiens)


name: Activation of GRIK3 homomer (Canis familiaris)


name: LDLR:LDL complex => LDLR + LDL (Sus scrofa)


name: IDUA hydrolyses Heparan sulfate chain(1) (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: ornithine-acyl [acyl carrier protein] N-acyltransferase activity


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + ethanolamine + H(+)


name: CO2 + excited coelenteramide h monoanion + H(+) + hnu => coelenterazine h + O2


name: Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Sus scrofa)


name: FLT3 ITD- and STAT5-dependent NOX4 gene expression (Homo sapiens)


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Caenorhabditis elegans)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Schizosaccharomyces pombe)


name: an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine => an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Mus musculus)


name: ent-kaur-16-en-19-ol + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-kaur-16-en-19-al + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: IL31:IL31RA:JAK1 binds OSMR:JAK1 (Sus scrofa)


name: RHOD GAPs stimulate RHOD GTPase activity (Mus musculus)


name: Furin cleaves pro-prothrombin to prothrombin (Mus musculus)


name: H(+) + hexadecanoyl-CoA + oxidized [electron-transfer flavoprotein] => (2E)-hexadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: a quinone + glutathione + H(+) + hydrogen sulfide <=> a quinol + S-sulfanylglutathione


name: 1D-myo-inositol 2-phosphate + phosphate => 1D-myo-inositol 2,3-bisphosphate + H2O


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine


name: ADP + glycochenodeoxycholate(out) + H(+) + phosphate => ATP + glycochenodeoxycholate(in) + H2O


name: Expression of Glutathione S-transferase omega-1 (Homo sapiens)


name: 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + H(+) + NADH => 3,4-dihydroxy-2-methyl-1-oxo-4-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NAD(+)


name: eburicol + O2 + reduced [NADPH--hemoprotein reductase] = 32-hydroxyeburicol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NFE2L2 binds CREBBP,EP300 (Caenorhabditis elegans)


name: S-methyl-5-thio-D-ribulose 1-phosphate <=> 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Mus musculus)


name: 3 A + 10 CO2 + 11 CoA + cordypyrone A + 8 H2O + 8 NADP(+) => acetyl-CoA + 3 AH2 + 18 H(+) + 10 malonyl-CoA + 8 NADPH


name: FGF2:TGFBR3 binding to GIPC1 (Canis familiaris)


name: 3,4-dihydroxybenzoyl-5'-AMP + holo-[aryl-carrier protein] <=> 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + H(+)


name: ROS oxidize thioredoxin (Canis familiaris)


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Xenopus tropicalis)


name: Peroxynitrite enters the bacterium (Homo sapiens)


name: Type I Na+-coupled phosphate co-transport (Homo sapiens)


name: mature p21 RAS binds GDP (Rattus norvegicus)


name: 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+) => 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine


name: dimethylallyl diphosphate + fumigaclavine A = diphosphate + fumigaclavine C


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: SLC26A3,6 exchange Cl- for HCO3- (Bos taurus)


name: Cables1 links CDK2 and WEE1 (Homo sapiens)


name: Gq alpha activates Phospholipase C beta (Homo sapiens)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Caenorhabditis elegans)


name: A + dihydrourocanate <=> AH2 + urocanate


name: N-acetylation of serotonin (Danio rerio)


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + CTP + H(+) = CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + diphosphate


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Homo sapiens)


name: a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GM2 (d18:1(4E)) + H(+) + UDP


name: NTRK2 phosphorylates CDK5 (Homo sapiens)


name: 1-dodecanoyl-sn-glycerol + H(+) + phosphocholine => 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O


name: UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 (Bos taurus)


name: chrodrimanin B + CoA => acetyl-CoA + chrodrimanin A


name: HEXB cleaves the terminal GalNAc from keratan sulfate (Xenopus tropicalis)


name: (2Z,6Z)-farnesyl diphosphate <=> beta-bisabolene + diphosphate


name: 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] + H(+) + NADH + O2 => 3,5-dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + H2O + NAD(+)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Rattus norvegicus)


name: SHC1 dissociates from integrin alphaIIb beta3 (Sus scrofa)


name: 2-hydroxyhexadecanoyl-CoA + CO2 + succinate => 2-oxoglutarate + hexadecanoyl-CoA + O2


name: (R)-prunasin + H2O = D-glucose + mandelonitrile


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Rattus norvegicus)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Xenopus tropicalis)


name: acetyl-CoA + dihydroxyacetone phosphate <=> 3-hydroxy-2,4-dioxopentyl phosphate + CoA


name: dTDP + H(+) + N(omega)-(alpha-L-rhamnosyl)-L-arginyl-[protein] => dTDP-beta-L-rhamnose + L-arginyl-[protein]


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Mus musculus)


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spheroidene => 2-hydroxyspheroidene + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Bos taurus)


name: a long-chain 2,3-saturated fatty acyl-CoA + O2 => a long-chain (2E)-enoyl-CoA + H2O2


name: an S-substituted L-cysteine => 2-aminoprop-2-enoate + a thiol


name: (2E,6E)-farnesyl diphosphate = (E)-gamma-bisabolene + diphosphate


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O => (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H(+)


name: (R)-carnitine(out) + glutarate(in) <=> (R)-carnitine(in) + glutarate(out)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Xenopus tropicalis)


name: RAC1 binds effectors at the plasma membrane (Sus scrofa)


name: Resynthesis of excised residue by POLB (Bos taurus)


name: RHOA:GTP translocates to the ER membrane (Gallus gallus)


name: ATP + ecdysone <=> ADP + ecdysone 22-phosphate + H(+)


name: a long-chain alkane + formate + H2O + 2 NADP(+) => a long-chain fatty aldehyde + H(+) + 2 NADPH + O2


name: Expression of GATA6 in cardiogenesis (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: 5,6-dihydrouridine(20) in tRNA + NAD(+) <=> H(+) + NADH + uridine(20) in tRNA


name: (E)-4-hydroxynon-2-en-1-ol + NADP(+) <=> (E)-4-hydroxynon-2-enal + H(+) + NADPH


name: cADPR-sensitive calcium-release channel activity


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Caenorhabditis elegans)


name: (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+) => (2E,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + H(+) + NADPH


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Mus musculus)


name: BIL dissociates from GSTA1, FABP1 (Danio rerio)


name: Release of E3 from polyubiquitinated substrate (Gallus gallus)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Bos taurus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O => (6S)-5,6,7,8-tetrahydrofolate + L-serine


name: RNF8 and RNF168 ubiquitinate KDM4A,B (Mus musculus)


name: guanosine(2535) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylguanosine(2535) in 23S rRNA + S-adenosyl-L-homocysteine


name: (d)AMP + ATP <=> (d)ADP + ADP (AK1) (Bos taurus)


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: LNK binds to p-KIT and inhibit downstream signaling (Homo sapiens)


name: Formation of ORC(2-5) complex (Bos taurus)


name: Estrogen-responsive MYB gene expression (Homo sapiens)


name: FarC-PTP4A2 binds RABGGTB (Plasmodium falciparum)


name: Association of procollagen type XII (Homo sapiens)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphate => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphate


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] <=> 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Gallus gallus)


name: n H(+)(in) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) => n H(+)(out) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out)


name: ATP + H2O + L-phenylalanine <=> AMP + D-phenylalanine + diphosphate + H(+)


name: FGFR1b binds to FGF (Drosophila melanogaster)


name: a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O


name: 3'-phosphoadenylyl sulfate + glycolithocholate => adenosine 3',5'-bisphosphate + H(+) + sulfoglycolithocholate


name: CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA (Homo sapiens)


name: Activation of MT-MMPs by FURIN (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate (Homo sapiens)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Plasmodium falciparum)


name: ATP + CoA + hexadecanedioate = AMP + diphosphate + hexadecanedioyl-CoA


name: ATP hydrolysis by HSP70 (Saccharomyces cerevisiae)


name: 12alpha,13alpha-dihydroxyfumitremorgin C + dimethylallyl diphosphate => diphosphate + fumitremorgin B


name: Nucleotide exchange on RAB1 (Rattus norvegicus)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Homo sapiens)


name: 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine + 2-heptanoyl-sn-glycero-3-phosphocholine = 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine + hexanoyl-sn-glycero-3-phosphoethanolamine


name: [aequorin]--dioxetanone <=> [excited state blue fluorescent protein] + CO2


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Caenorhabditis elegans)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: proMMP9 binds TIMP1 (Drosophila melanogaster)


name: S-adenosyl-L-methionine + syringetin <=> 7,3',5'-O-trimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: 4-hydroxybenzoate + all-trans-nonaprenyl diphosphate => 4-hydroxy-3-all-trans-nonaprenylbenzoate + diphosphate


name: acetate + N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine => H2O + N,N'-diacetylchitobiose


name: proton-transporting ATPase activity, rotational mechanism


name: WNT5A binds FZD and ROR receptors (Rattus norvegicus)


name: 2-deoxyecdysone + phosphate => 2-deoxyecdysone 22-phosphate + H2O


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Homo sapiens)


name: SCF-FBXL7 ubiquitinates AURKA (Canis familiaris)


name: 2,5-dichlorohydroquinone + 2 glutathione = chloride + chlorohydroquinone + glutathione disulfide + H(+)


name: Activation of TAK1-TAB2 complex (Homo sapiens)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Drosophila melanogaster)


name: AcCho is hydrolyzed to Cho and acetate by ACHE (Drosophila melanogaster)


name: L-altrarate => 5-dehydro-4-deoxy-D-glucarate + H2O


name: PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Mus musculus)


name: a long-chain fatty acid + ATP + holo-[ACP] = a long-chain fatty acyl-[ACP] + AMP + diphosphate


name: CaMKK autophosphorylates in the cytosol (Schizosaccharomyces pombe)


name: Ubiquitinated Cdc6 is degraded by the proteasome (Plasmodium falciparum)


name: Fibrillin 1, 2,(3) degradation by MMP2, 9, 12 and 13 (Canis familiaris)


name: Retromer recycles WLS to the Golgi (Bos taurus)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Xenopus tropicalis)


name: 10,11-epoxy-(7Z,13Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Budding of connexon-containing transport vesicles from the Golgi (Xenopus tropicalis)


name: H(+) + 2 H2O + pyridinestrone carboxylate => (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + NH4(+)


name: Cysteine from cystathionine and vice versa (Mycobacterium tuberculosis)


name: ING2-bound EP300 acetylates TP53 (Xenopus tropicalis)


name: PAK1-3 autophosphorylates (Drosophila melanogaster)


name: Self-ubiquitination of RNF41 (Homo sapiens)


name: AXIN is phosphorylated in the destruction complex (Homo sapiens)


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Saccharomyces cerevisiae)


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Dictyostelium discoideum)


name: a (2E)-enoyl-[ACP] + H2O => a (3R)-hydroxyacyl-[ACP]


name: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: CHEK2 phosphorylates BRCA1 (Homo sapiens)


name: chorismate + L-glutamine = 4-amino-4-deoxychorismate + L-glutamate


name: FADH2-C4alpha-hydroperoxide + NADH + rifampicin = FADH2 + H(+) + H2O + NAD(+) + rifampicin hemiaminal


name: RAR:RXR binds SUMO-CRABP2:atRA (Sus scrofa)


name: p62 binds ubiquitinated mitochondrial substrates (Xenopus tropicalis)


name: Interaction of integrin alpha8beta1 with Tenascin-C (Mus musculus)


name: L-histidine(in) + Na(+)(in) => L-histidine(out) + Na(+)(out)


name: alcohol glucuronate acceptor + UDP-alpha-D-glucuronate <=> a beta-D-glucuronoside + H(+) + UDP


name: chloride(out) + L-leucine(out) + 2 Na(+)(out) => chloride(in) + L-leucine(in) + 2 Na(+)(in)


name: Thrombin-activated PARs binds G-protein Gq (Caenorhabditis elegans)


name: MITF-M-dependent ATP6V1C1 gene expression (Homo sapiens)


name: carbohydrate transmembrane transporter activity


name: Fgr may phosphorylate p38 MAPK (Drosophila melanogaster)


name: FOXO1,FOXO3,FOXO4 bind p-2S-SMAD2/3:SMAD4 (Bos taurus)


name: SARS-CoV-1 7a binds BCL2L1 (Homo sapiens)


name: L-phenylalanine + ochratoxin alpha => H2O + ochratoxin A


name: cyanidin 3-O-beta-D-galactoside + H(+) + UDP => cyanidin + UDP-alpha-D-galactose


name: 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide => 1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Mus musculus)


name: TP53 binds promoters of MIR34 genes (Homo sapiens)


name: Proton-coupled histidine and di-peptide cotransport (Saccharomyces cerevisiae)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Mus musculus)


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Homo sapiens)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Bos taurus)


name: IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Bos taurus)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Xenopus tropicalis)


name: AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide => H2O + NADH


name: a ganglioside GQ1c + N-acetylneuraminate => a ganglioside GP1c + H2O


name: 5alpha-cholestan-7-oxo-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => lathosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: ent-copalyl diphosphate + H2O = (-)-ent-copalol + diphosphate


name: (3R)-3-hydroxy-L-aspartate <=> NH4(+) + oxaloacetate


name: GLTP transports GSL from plasma membrane to ER membrane (Xenopus tropicalis)


name: Activated NOD oligomer recruites RIP2 (RICK) (Homo sapiens)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Drosophila melanogaster)


name: PIAS1,2-1 SUMOylates XRCC4 with SUMO1 (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate


name: H(+) + NADPH + oxaloacetate => (S)-malate + NADP(+)


name: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H(+)


name: carbamoyl adenylate + tobramycin => AMP + H(+) + nebramycin 5'


name: Duplex siRNA is loaded into Argonaute (Drosophila melanogaster)


name: AMP + 2 H(+) + pyridinium-3,5-dicarboxylate mononucleotide => deamido-NAD(+) + hydrogencarbonate


name: CO2 + N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] => 2-oxoglutarate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase]


name: N-WASP binds ARP2/3 and G-actin (Homo sapiens)


name: Reducing equivalents from beta-oxidation of fatty acids transfer to ETF (Saccharomyces cerevisiae)


name: H2O + NADP(+) + pentyl acetate => H(+) + heptan-2-one + NADPH + O2


name: SLC2A9 transports Fru, Glc, urate (Saccharomyces cerevisiae)


name: Vamp8 associated secretory vesicle to plasma membrane transport (Sus scrofa)


name: 17alpha-estradiol + NAD(+) => estrone + H(+) + NADH


name: 3 H(+) + H2O + urea-1-carboxylate <=> 2 CO2 + 2 NH4(+)


name: branched 1,3-beta-D-glucan synthase activity


name: glycerol-3-phosphate transmembrane transporter activity


name: UGCG transfers glucose to ceramide (Mus musculus)


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Xenopus tropicalis)


name: Activation of Edited Kainate receptors (Drosophila melanogaster)


name: 3-oxo-3-phenylpropanoate + L-alanine => (S)-3-amino-3-phenylpropanoate + pyruvate


name: Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA (Xenopus tropicalis)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Rattus norvegicus)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 = 10-hydroperoxy-(8Z,11Z,14Z)-eicosatrienoate


name: (+)-artemisinic aldehyde + O2 + reduced [NADPH--hemoprotein reductase] <=> (+)-artemisinate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Schizosaccharomyces pombe)


name: Activated MET binds GAB1 and GRB2 (Sus scrofa)


name: CYP17A1 cleaves 17aHPROG to ANDST (Mus musculus)


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)


name: p-Y397-PTK2 binds SRC (Rattus norvegicus)


name: Transfer of NEDD8 to AcM-UBE2F (Bos taurus)


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Bos taurus)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Sus scrofa)


name: L1 trans-homophilic interaction (Homo sapiens)


name: 2-oxoglutarate + berkeleyone A + O2 <=> CO2 + H2O + preaustinoid A + succinate


name: snRNP nuclear import and release (Mus musculus)


name: indole-3-carbonyl nitrile + O2 + reduced [NADPH--hemoprotein reductase] => 4-hydroxy-indole-3-carbonyl nitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Homo sapiens)


name: Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Homo sapiens)


name: Translocation of ERBB4s80 to the nucleus (Canis familiaris)


name: 2-oxoglutarate(out) + oxaloacetate(in) = 2-oxoglutarate(in) + oxaloacetate(out)


name: H2O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate


name: PIAS3 SUMOylates MITF with SUMO1 (Mus musculus)


name: 1-acyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: SMYD2 methylates TP53 (Canis familiaris)


name: ALOX15 oxidises 17(S)-Hp-DHA to PDX (Bos taurus)


name: Phosphorylated AP-1, Phospho JRA:Phospho KAY dissociates from CKA (Drosophila melanogaster)


name: 5-methylcytidine(4447) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine


name: androsterone 3alpha-sulfate(out) + 2 Na(+)(out) <=> androsterone 3alpha-sulfate(in) + 2 Na(+)(in)


name: MAT1A multimers transfer Ado from ATP to L-Met (Homo sapiens)


name: (3S)-3-hydroxypentanoyl-CoA + H2O => (3S)-3-hydroxypentanoate + CoA + H(+)


name: SYK binds to integrin alphaIIb beta3 (Homo sapiens)


name: AMP + diphosphate + L-arginyl-[peptidyl-carrier protein] => ATP + holo-[peptidyl-carrier protein] + L-arginine


name: (2E,6E)-farnesyl diphosphate + 2 H2O = 7-epi-ent-eudesmane-5,11-diol + diphosphate


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Canis familiaris)


name: 2-oxoglutarate + deoxyamidinoproclavaminate + O2 <=> amidinoproclavaminate + CO2 + succinate


name: 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: PIAS1,2-2 SUMOylate PPARG with SUMO1 (Homo sapiens)


name: Brevican degradation by ADAMTS4, ADAMTS5 (Mus musculus)


name: cucurbitacin B + H(+) + NADH => 23,24-dihydrocucurbitacin B + NAD(+)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Drosophila melanogaster)


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Canis familiaris)


name: Transfer of Fe-S clusters to SDHB (Mus musculus)


name: Cargo Recognition And Sorting (Rattus norvegicus)


name: Dopachrome is transformed to DHICA by DCT (Homo sapiens)


name: Assembly of hexameric IL-6 receptor (Bos taurus)


name: p-Y420-FYN is phosphorylated on S21 (Drosophila melanogaster)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Sus scrofa)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Bos taurus)


name: ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Mus musculus)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Homo sapiens)


name: beta-alanine(out) + n H(+)(in) => beta-alanine(in) + n H(+)(out)


name: H2O + NADP(+) + staphylopine <=> (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + NADPH + pyruvate


name: Transport of fringe-modified NOTCH to plasma membrane (Xenopus tropicalis)


name: 3-(3-hydroxyphenyl)pyruvate + L-glutamate => 2-oxoglutarate + 3-hydroxy-L-phenylalanine


name: H(+) + hydrogen sulfide + NH4(+) + pyruvate => H2O + L-cysteine


name: SUMOylation of RXRA with SUMO1 (Danio rerio)


name: HTR1 and 5A receptors can bind serotonin (Caenorhabditis elegans)


name: Factor H binds to C3b (Canis familiaris)


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Homo sapiens)


name: a ganglioside Ac-O-7-GD2(d18:1(4E)) => a ganglioside Ac-O-8-GD2(d18:1(4E))


name: alpha-methylbutyryl-CoA + FAD => tiglyl-CoA + FADH2 (Homo sapiens)


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Rattus norvegicus)


name: RGGT binds the RAB-binding subunit (Canis familiaris)


name: eNOS translocation from Golgi to Caveolae (Homo sapiens)


name: kallikrein binds SERPING1 (Gallus gallus)


name: 2 (4Z,15Z)-bilirubin IXalpha + O2 = 2 biliverdin IXalpha + 2 H2O


name: 2 mycothiol + NADP(+) => H(+) + mycothione + NADPH


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin = 2-hydroxyspirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SUMOylation of TFAP2C with SUMO1 (Homo sapiens)


name: PRKN polyubiquitinates RIPK3 (Mus musculus)


name: 2 Fe(III)-[cytochrome c] + H2O + nitrous oxide = 2 Fe(II)-[cytochrome c] + 2 H(+) + 2 nitric oxide


name: DHCR7 reduces 7-dehydroCHOL to CHOL (Caenorhabditis elegans)


name: 3 hydrogencarbonate(out) + Na(+)(out) = 3 hydrogencarbonate(in) + Na(+)(in)


name: a bacteriochlorophyllide f + H2O => a 7(1),7(1)-dihydroxybacteriochlorophyllide d


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Saccharomyces cerevisiae)