name: 19-hydroxy-11-deoxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 19-oxo-11-deoxycorticosterone + 2 H2O + 2 oxidized [adrenodoxin]


name: SLC7A10-mediated uptake of small neutral amino acids (Canis familiaris)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Xenopus tropicalis)


name: Reduction of disulphide bonds in MHC II antigens (Rattus norvegicus)


name: Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)


name: (9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA => (9Z)-octadecenoyl-CoA + sn-glycero-3-phosphoethanolamine


name: an (S)-2-haloacid + H2O <=> a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+) => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate


name: 3-oxoadipate + NADP(+) = H(+) + maleylacetate + NADPH


name: 4-methylcatechol + CO2 + NADH => (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Schizosaccharomyces pombe)


name: factor V -> factor Va + factor V activation peptide (Homo sapiens)


name: SYK binds the activated BCR (Sus scrofa)


name: an acyl-CoA + sn-glycerol 3-phosphocholine <=> a 1-acyl-sn-glycero-3-phosphocholine + CoA


name: tissue factor (TF) + factor VII (F7) -> TF:F7 complex (Mus musculus)


name: a carboxylate + ATP + CoA <=> AMP + an acyl-CoA + diphosphate


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Danio rerio)


name: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate


name: SDHAF4 binds to FAD-SDHA (Saccharomyces cerevisiae)


name: Autophosphorylation and activation of MEKK1 (Homo sapiens)


name: DHFR dimer binds DHFR inhibitors (Mus musculus)


name: acetyl-CoA + N-acetylneuraminate <=> CoA + N-acetyl-9-O-acetylneuraminate


name: SUCLG1/G2 cleaves succinyl-CoA (Drosophila melanogaster)


name: 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O <=> 2-oxopent-4-enoate + salicylate


name: H2O + luteolin 7-O-beta-D-glucoside => beta-D-glucose + luteolin


name: a 1,2-saturated acyl-CoA + an acyl-CoA + H2O => an (R)-2-alkyl-3-oxoalkanoate + 2 CoA + H(+)


name: hexadecanoyl-CoA + sphinga-4E,14Z-dienine = CoA + H(+) + N-hexadecanoyl-sphinga-4E,14Z-dienine


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Schizosaccharomyces pombe)


name: 3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O2 <=> 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)


name: PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Danio rerio)


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Mus musculus)


name: PGLYRP2 binds bacterial peptidoglycan (Drosophila melanogaster)


name: ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate


name: coelenterazine h dioxetanone => coelenterazine h + O2


name: MET bound PI3K generates PIP3 (Caenorhabditis elegans)


name: MASTL (GWL) phosphorylates ARPP19 (Saccharomyces cerevisiae)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Homo sapiens)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Rattus norvegicus)


name: Na(+)(in) + tellurite(in) => Na(+)(out) + tellurite(out)


name: P4HB:4-Hyp collagen propeptides dissociates (Danio rerio)


name: a 2,3-dehydroacyl-CoA + H(+) + NADPH => a 2,3-saturated acyl-CoA + NADP(+)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Homo sapiens)


name: RHOD GAPs stimulate RHOD GTPase activity (Drosophila melanogaster)


name: quercitrin + UDP-beta-L-rhamnose => H(+) + quercetin 3,7-bis-O-alpha-L-rhamnoside + UDP


name: 2-deoxy-D-glucose 6-phosphate + NADP(+) = 2-deoxy-6-phospho-D-glucono-1,5-lactone + H(+) + NADPH


name: Activation of proMMP9 by proteases (Bos taurus)


name: ATP Hydrolysis By Myosin (Rattus norvegicus)


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Sus scrofa)


name: Release of platelet cytosolic components (Canis familiaris)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Xenopus tropicalis)


name: H2O + N-(aminomethyl)urea = N-(hydroxymethyl)urea + NH4(+)


name: Cleavage of p-STK3 (p-MST2) by caspase 3 (Canis familiaris)


name: ADP + H(+) + leukotriene C4(out) + phosphate => ATP + H2O + leukotriene C4(in)


name: PPM1K dephosphorylates p-BCKDH (Homo sapiens)


name: 15-cis-4,4'-diapophytoene + 4 FAD + 4 H(+) = all-trans-4,4'-diapolycopene + 4 FADH2


name: ATP + H2O + indoxyl sulfate(in) <=> ADP + H(+) + indoxyl sulfate(out) + phosphate


name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Rattus norvegicus)


name: linalool + O2 + reduced [NADPH--hemoprotein reductase] <=> (6E)-8-hydroxylinalool + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (3S)-1,2-diazinane-3-carboxylate + H(+) + H2O => N(5)-hydroxy-L-ornithine


name: Recruitment of GADS:SLP-76 to p-5Y-LAT (Mus musculus)


name: (2S,3S)-versiconal hemiacetal acetate + H2O => (2S-3S)-versiconal hemiacetal + acetate + H(+)


name: (12R,13S)-epoxy-(9Z)-octadecenoate + O2 <=> (12R,13S)-epoxy-(10R)-hydroperoxy-(8E)-octadecenoate


name: 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol <=> 4-O-[(D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)


name: FURIN translocates to the plasma membrane (Schizosaccharomyces pombe)


name: (R)-octopamine <=> (4-hydroxyphenyl)acetaldehyde + NH4(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine <=> 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin


name: Acidification of Tf:TfR1 containing endosome (Bos taurus)


name: N-hydroxy-L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Homo sapiens)


name: CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Mus musculus)


name: chloride(out) + L-tyrosine(out) + 2 Na(+)(out) <=> chloride(in) + L-tyrosine(in) + 2 Na(+)(in)


name: (3S)-hydroxytetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O


name: a 3-oxoacyl-CoA + CoA => acetyl-CoA + an acyl-CoA


name: JMJD6 demethylates MeR3-histone H3 (Caenorhabditis elegans)


name: Collagen type XII degradation by MMP12 (Mus musculus)


name: 2-hydroxy-3-oxoadipate + CO2 => 2-oxoglutarate + glyoxylate + H(+)


name: a ganglioside GA1 + GDP-beta-L-fucose <=> a ganglioside Fuc-GA1 + GDP + H(+)


name: dTDP-D-galactose + H2O + 2 NADP(+) = dTDP-D-galacturonate + 3 H(+) + 2 NADPH


name: Factor Xa inhibitors binds Xa (Mus musculus)


name: glyoxylate + N(omega),N('omega)-dimethyl-L-arginine = 5-(3,3'-dimethylguanidino)-2-oxopentanoate + glycine


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Bos taurus)


name: Assembly of hexameric IL-6 receptor (Canis familiaris)


name: Expression of FABP6 regulated by NR1H2,3 (Homo sapiens)


name: Activated FGFR4 phosphorylates FRS3 (Bos taurus)


name: Disassembly of tight junctions (Canis familiaris)


name: DDIT4 binds 14-3-3 dimer (Drosophila melanogaster)


name: The phagophore extends from the PIP3-enriched structure (Homo sapiens)


name: 2-hydroxyethane-1-sulfonate(out) + Na(+)(out) => 2-hydroxyethane-1-sulfonate(in) + Na(+)(in)


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Homo sapiens)


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Homo sapiens)


name: UDP-beta-L-arabinofuranose(out) + UMP(in) => UDP-beta-L-arabinofuranose(in) + UMP(out)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Bos taurus)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2 => 2-dehydro-D-glucose + H2O2 + L-phenylalanine


name: (S)-reticuline + S-adenosyl-L-methionine = (S)-tembetarine + H(+) + S-adenosyl-L-homocysteine


name: 3-chloro-D-alanine + H2O = chloride + H(+) + NH4(+) + pyruvate


name: H2O + N-hexadecanoylethanolamine => ethanolamine + hexadecanoate


name: beta-dihydromenaquinone-9 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + omega-hydroxy-beta-dihydromenaquinone-9 + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Mus musculus)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Rattus norvegicus)


name: Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Homo sapiens)


name: SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Sus scrofa)


name: 11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA


name: PTPN3 binds p-T183,Y185 MAPK12 (Gallus gallus)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Xenopus tropicalis)


name: mRNA4 is translated to protein E (Homo sapiens)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Bos taurus)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Saccharomyces cerevisiae)


name: 8-oxo-dGMP + 2 H(+) + 2 phosphate => 8-oxo-dGTP + 2 H2O


name: 1-O-(trans-sinapoyl)-beta-D-glucose + anthocyanin A8 = anthocyanin A11 + D-glucose


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Bos taurus)


name: XDH dehydrogenates hypoxanthine to form xanthine (Mus musculus)


name: D-glucose + NAD(+) => D-glucono-1,5-lactone + H(+) + NADH


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,3-di-(9Z-octadecenoyl)-glycerol


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Rattus norvegicus)


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Sus scrofa)


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Homo sapiens)


name: Initial activation of proMMP13 by MMP3 (Mus musculus)


name: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate => 3-carboxy-cis,cis-muconate + H(+)


name: 2-glyceryl-prostaglandin H2 = 2-glyceryl-prostaglandin D2


name: H(+)(out) + minocycline(in) = H(+)(in) + minocycline(out)


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Rattus norvegicus)


name: (2E)-geranyl diphosphate => alpha-thujene + diphosphate


name: (+)-(R)-germacrene A + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = germacra-1(10),4,11(13)-trien-12-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: 2 A + hydroxylamine + NH4(+) <=> 2 AH2 + H(+) + H2O + N2


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate => a 5'-end ribonucleotide-tRNA(His) + ATP + H(+)


name: (20S)-ginsenoside Rh1 + H(+) + UDP => (20S)-protopanaxatriol + UDP-alpha-D-glucose


name: N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate (Homo sapiens)


name: glycine + indole-3-pyruvate => glyoxylate + L-tryptophan


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Canis familiaris)


name: AXIN is phosphorylated in the destruction complex (Gallus gallus)


name: ADP + coproporphyrin I(out) + H(+) + phosphate => ATP + coproporphyrin I(in) + H2O


name: ELANE, CTSG or PRTN3 binds bacteria (Rattus norvegicus)


name: cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Bos taurus)


name: D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate


name: HAGH hydrolyses (R)-S-LGSH to GSH and LACT (Dictyostelium discoideum)


name: TTYH1 transports cytosolic Cl- to extracellular region (Drosophila melanogaster)


name: (S)-ureidoglycolate + NAD(+) <=> H(+) + N-carbamoyl-2-oxoglycine + NADH


name: beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + D-galactose => alpha-D-Gal-(1->6)-beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + H2O


name: P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential


name: PPA2A dephosphorylates SPRY2 (Homo sapiens)


name: TGFB1,TGFB2 bind TGFBR3 (Rattus norvegicus)


name: PRKACA phosphorylates PLN (Xenopus tropicalis)


name: Acireductone is created (Drosophila melanogaster)


name: a 5'-end ribonucleotide-tRNA(His) + ATP + GTP + H2O => a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)


name: CRYM reduces P2C to PPCA (Drosophila melanogaster)


name: PIP3 recruits PDPK1 to the membrane (Gallus gallus)


name: CO2 + formaldehyde + neomorphinone + succinate => 2-oxoglutarate + O2 + oripavine


name: PRODH oxidises L-Pro to 1PYR-5COOH (Schizosaccharomyces pombe)


name: malonyl-CoA + S-adenosyl-L-methionine => malonyl-CoA methyl ester + S-adenosyl-L-homocysteine


name: RHOB translocates to the endosome membrane (Xenopus tropicalis)


name: 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one => 3-hydroxyhispidin + O2


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ATP + H2O = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ADP + H(+) + phosphate


name: cis-3-hydroxy-L-proline => 1-pyrroline-2-carboxylate + H2O


name: 27-hydroxywithanone + UDP-alpha-D-glucose => H(+) + UDP + withanone 27-O-beta-D-glucoside


name: p62 is recruited and forms a complex with TRAF6 (Rattus norvegicus)


name: glycine(in) + L-phenylalanine(out) => glycine(out) + L-phenylalanine(in)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Plasmodium falciparum)


name: 2 chloride(out) + glycine betaine(out) + 3 Na(+)(out) <=> 2 chloride(in) + glycine betaine(in) + 3 Na(+)(in)


name: Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide (Sus scrofa)


name: Activation of Ca impermeable AMPA receptors (Drosophila melanogaster)


name: H(+) + NADPH + UDP-4-dehydro-beta-L-rhamnose => NADP(+) + UDP-beta-L-rhamnose


name: Exocytosis of specific granule membrane proteins (Schizosaccharomyces pombe)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin IV => O2 + proatranorin I + reduced [NADPH--hemoprotein reductase]


name: (E,E)-piperate + ATP + CoA => (E,E)-piperoyl-CoA + AMP + diphosphate


name: (9Z)-octadecenoyl-CoA + octadecan-1-ol <=> 1-O-octadecyl (9Z)-octadecenoate + CoA


name: Translocation of RIAM to plasma membrane (Rattus norvegicus)


name: (S)-benzodiazepinedione + dimethylallyl diphosphate = (2R,3S,11S)-aszonalenin + diphosphate


name: ACY1:Zn2+ dimer hydrolyses mercapturic acids (Drosophila melanogaster)


name: ATXN3 family cleave Ub chains (Caenorhabditis elegans)


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Rattus norvegicus)


name: Aquaporins passively transport glycerol into cells (Saccharomyces cerevisiae)


name: thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Dictyostelium discoideum)


name: FAD + L-threonyl-[protein] <=> AMP + FMN-L-threonyl-[protein] + H(+)


name: LCAT:spherical HDL complex <=> LCAT + spherical HDL (Mus musculus)


name: 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + CO2 + CoA => (15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + H(+) + malonyl-CoA


name: EP2 subtype prostaglandin E2 receptor binding


name: Integrin alpha5beta1 binds FN1 dimer (Caenorhabditis elegans)


name: FURIN translocates to the plasma membrane (Saccharomyces cerevisiae)


name: 2 H(+) + hexanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 5-hexenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: AXIN mutants destabilize the destruction complex (Homo sapiens)


name: Furin cleaves pro-protein S to protein S (Bos taurus)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Danio rerio)


name: ORC5 binds ORC2:ORC3 (Dictyostelium discoideum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol


name: 4',4'-dihydroxyechinenone <=> canthaxanthin + H2O


name: H2O + N-formylmethanofuran <=> formate + methanofuran


name: 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase] => 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Mus musculus)


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Rattus norvegicus)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+)


name: a uridine in rRNA + S-adenosyl-L-methionine = a 2'-O-methyluridine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + P(1),P(2)-bis(5'-adenosyl) diphosphate <=> 2 AMP + 2 H(+)


name: USP34 deubiquitinates AXIN1,AXIN2 (Homo sapiens)


name: Activated TLR5/TLR15 homodimer recruits MyD88 adaptor (Gallus gallus)


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Xenopus tropicalis)


name: cholate + NADP(+) <=> 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADPH


name: GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Caenorhabditis elegans)


name: SUMOylation of TOP2A with SUMO1 (Schizosaccharomyces pombe)


name: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH


name: 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + UDP => di-trans,octa-cis-undecaprenyl phosphate + UDP-4-deoxy-4-formamido-beta-L-arabinose


name: PC carboxylates PYR to OA (Homo sapiens)


name: Caspase-mediated cleavage of GAS2 (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoate + glycerol + H(+) => 1-(9Z,12Z-octadecadienoyl)-glycerol + H2O


name: YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Danio rerio)


name: PI is hydrolyzed to 2-acyl LPI by PLA2[13] (Bos taurus)


name: JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 (Homo sapiens)


name: 3-hydroxybutanoyl-CoA => (2E)-butenoyl-CoA + H2O


name: Interaction of integrin alpha9beta1 with VCAM1 (Canis familiaris)


name: a catechol + S-adenosyl-L-methionine => a guaiacol + H(+) + S-adenosyl-L-homocysteine


name: Co-precorrin-4 + S-adenosyl-L-methionine <=> Co-precorrin-5A + H(+) + S-adenosyl-L-homocysteine


name: 24-methylenecycloartanol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: (R)-adrenaline + H2O + O2 => (R)-3,4-dihydroxymandelaldehyde + H2O2 + methylamine


name: H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] => N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase]


name: PPP1CC dephosphorylates PLK1 (Gallus gallus)


name: ADP + glutaryl-CoA + phosphate => ATP + CoA + glutarate


name: 3 2-oxoglutarate + gibberellin A12 + 3 O2 = 3 CO2 + gibberellin A25 + H(+) + H2O + 3 succinate


name: Phosphorylated WTS autophosphorylates (Drosophila melanogaster)


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Mus musculus)


name: PITPNM1,2,3 exchange PI for PA (Bos taurus)


name: Translocation of p21 to the nucleus (Homo sapiens)


name: PTPN1 dephosphorylates PTK6 (Bos taurus)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + butanoate + H(+) => 1-O-hexadecyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O


name: 10-formyldihydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-thiocarboxamide = 6-thio-IMP + 7,8-dihydrofolate + H2O


name: TRAF1 is cleaved by caspases (Bos taurus)


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Mus musculus)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sphinganine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + sphinganine


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Canis familiaris)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Drosophila melanogaster)


name: CK1 phosphorylates p-GLI3 (Canis familiaris)


name: HRSP12 deaminates 2AA to 2OBUTA (Danio rerio)


name: 3,4-dichlorocatechol + O2 <=> (2Z,4Z)-2,3-dichloromuconate + 2 H(+)


name: MITF-M binds the promoters of v-ATPase target genes (Homo sapiens)


name: 3-dehydro-L-gulonate + H(+) => CO2 + L-xylulose


name: p-AMPK:AMP binds the ULK complex (Sus scrofa)


name: ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H2O + L-glutamine <=> ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + L-glutamate + phosphate


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Gallus gallus)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Canis familiaris)


name: pS181-S-Farn-Me KRAS4B binds BCL2L1 (Rattus norvegicus)


name: a short-chain 3-oxoacyl-CoA + H(+) + NADH => a short-chain (3R)-hydroxy fatty acyl-CoA + NAD(+)


name: 7-chloro-L-tryptophan + AH2 + O2 <=> A + CO2 + 2 H2O + monodechloroaminopyrrolnitrin


name: ERBB4 binds NRGs or EGF-like ligands (Canis familiaris)


name: UROD decarboxylates URO3 to COPRO3 (Homo sapiens)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc6S + H2O => 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine 6-sulfate


name: RHOG GAPs stimulate RHOG GTPase activity (Canis familiaris)


name: USP8 deubiquitinates STAM2:HGS (Bos taurus)


name: PTPN22 dissociates from CSK (Rattus norvegicus)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Homo sapiens)


name: UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Drosophila melanogaster)


name: MCAT transfers Mal from Mal-CoA to NDUFAB1 (Schizosaccharomyces pombe)


name: a fatty acid + H(+) + sn-glycero-3-phospho-L-serine => a 1-acyl-sn-glycero-3-phospho-L-serine + H2O


name: chenodeoxycholate + NAD(+) <=> 3-oxochenodeoxycholate + H(+) + NADH


name: decanoyl-[ACP] + H2O = decanoate + H(+) + holo-[ACP]


name: 3-phenylpyruvate + L-tryptophan <=> indole-3-pyruvate + L-phenylalanine


name: glucoside transmembrane transporter activity


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Dictyostelium discoideum)


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Caenorhabditis elegans)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Canis familiaris)


name: Cu(2+)(out) + L-ascorbate(in) => Cu(+)(out) + H(+) + monodehydro-L-ascorbate radical(in)


name: HMGB1 binds LTP (Schizosaccharomyces pombe)


name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Drosophila melanogaster)


name: Activation of Calcineurin (Canis familiaris)


name: PLK1 phosphorylates NUDC (Plasmodium falciparum)


name: 2Fe-2S is inserted in UQCRFS1 (Saccharomyces cerevisiae)


name: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate


name: NFE2L2 dependent PDGFA expression (Homo sapiens)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Bos taurus)


name: USP19 binds HIF1A,BIRC2,BIRC3 (Gallus gallus)


name: ARFRP1 recruits ARL1 to the TGN (Gallus gallus)


name: Dissociation of RAS:RAF complex (Mus musculus)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Canis familiaris)


name: Formation of ARC coactivator complex (Homo sapiens)


name: Cleavage of ERBB4m80 by gamma-scretase complex (Danio rerio)


name: Recruitment of SYK to phosphorylated ITAMs (Rattus norvegicus)


name: ATXN3 binds polyUb-PARK2 (Gallus gallus)


name: PPM1D dephosphorylates RUNX2 (Sus scrofa)


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Golgi lumen glycoconjugates translocate to the plasma membrane (Homo sapiens)


name: guaiacol + H(+) + S-adenosyl-L-homocysteine => catechol + S-adenosyl-L-methionine


name: USP12, USP26 deubiquitinate AR (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate => diphosphate + gamma-himachalene


name: a ganglioside GD2 + UDP-alpha-D-galactose <=> a ganglioside GD1b + H(+) + UDP


name: Duplex miRNA is loaded into Argonaute (Caenorhabditis elegans)


name: N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine => alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: PG and CDP-DAG are converted to CL by CRLS1 (Rattus norvegicus)


name: Caspase mediated cleavage of APC (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: (1S,4R)-menthone + H(+) + NADPH + O2 = (4S,7R)-7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+)


name: 1-carboxybiuret + H(+) => cyanurate + H2O


name: Cannabinoid receptors can bind cannabinoids (Bos taurus)


name: H2O + UDP-4-dehydro-6-deoxy-alpha-D-glucose => UDP-alpha-D-glucose


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Mus musculus)


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Sus scrofa)


name: RAC1 and CDC42 activate PAK2 (Gallus gallus)


name: 2-acyl LPI is acylated to PI by MBOAT7 (Drosophila melanogaster)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Drosophila melanogaster)


name: dihydrochelirubine + NAD(+) = chelirubine + NADH


name: Proteasomal clevage of exogenous antigen (Dictyostelium discoideum)


name: SHC1 phosphorylation by phosphorylated EGFR (Xenopus tropicalis)


name: JMJD6 demethylates MeR3-histone H3 (Sus scrofa)


name: acetyl-CoA + H2O => acetate + CoASH (Homo sapiens)


name: acetyl-CoA + 2 H(+) + 2 malonyl-CoA => 2 CO2 + 3 CoA + triacetate lactone


name: an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Ubiquitination of PAK-2p34 (Homo sapiens)


name: PE is hydrolyzed to 2-acyl LPE by PLA2G4C (Mus musculus)


name: Fibrillin-1 degradation by ELANE (Homo sapiens)


name: Caspase mediated cleavage of beta-catenin (Sus scrofa)


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Caenorhabditis elegans)


name: p-S232-S237-P is further phosphorylated (Homo sapiens)


name: a nucleoside 2'-phosphate + H(+) => a nucleoside 2',3'-cyclic phosphate + H2O


name: 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 <=> 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) (Gallus gallus)


name: IRAK4 is activated by autophosphorylation (Homo sapiens)


name: a nucleoside 2',3'-cyclic phosphate + H2O <=> a nucleoside 3'-phosphate + H(+)


name: Binding of ATRA to TGFBR3 gene promoter (Homo sapiens)


name: (5R)-hydroxy-beta-trans-bergamotene + O2 = (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + H2O


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Saccharomyces cerevisiae)


name: RHOA binds effectors at the ER membrane (Gallus gallus)


name: a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + diphosphate => a 5'-end diphospho-guanosine in mRNA + GTP + H(+)


name: Collagen type III degradation by MMP1,8,9,13 (Xenopus tropicalis)


name: ATP + L-tryptophan <=> diphosphate + L-tryptophyl-5'-AMP


name: LIPT2 transfers octanoyl group to GCSH (Gallus gallus)


name: GLI:SUFU dissociates (Rattus norvegicus)


name: 16 ATP + 16 H2O + N2 + 4 reduced [flavodoxin] = 16 ADP + 18 H(+) + H2 + 2 NH4(+) + 4 oxidized [flavodoxin] + 16 phosphate


name: Pink1 is cleaved on healthy mitochondria (Homo sapiens)


name: Interleukin-5 is a homodimer (Homo sapiens)


name: RAR:RXR binds SUMO-CRABP2:atRA (Homo sapiens)


name: 4-hydroxybenzoyl-CoA + chloride + H(+) => 4-chlorobenzoyl-CoA + H2O


name: guanyl nucleotide exchange factor inhibitor activity


name: AH2 + L-thyroxine => 3,3',5'-triiodo-L-thyronine + A + H(+) + iodide


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Canis familiaris)


name: CASP14 cleaves filaggrin (Canis familiaris)


name: carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate


name: Chloride ion and N-acyl group react to chloramide (Homo sapiens)


name: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnose + H2O => 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose


name: Phosphorylation of Cyclin A:Cdk2 at Tyr 15 (Schizosaccharomyces pombe)


name: AKT1 phosphorylates eNOS (Drosophila melanogaster)


name: 4-acetamidobutanoate + 2 H(+) + NADH => 4-acetamidobutanal + H2O + NAD(+)


name: NR3C2 binds NR3C2 antagonists (Danio rerio)


name: structural constituent of synapse-associated extracellular matrix


name: SGK phosphorylates CREB1 (Caenorhabditis elegans)


name: p-Y705-STAT3 binds p-Y693-STAT4 (Bos taurus)


name: ERCC2 and ERCC3 DNA helicases form an open bubble structure in damaged DNA (Mus musculus)


name: trans-Golgi Network Lysosomal Vesicle Scission (Canis familiaris)


name: RHOA GAPs stimulate RHOA GTPase activity (Drosophila melanogaster)


name: PC carboxylates PYR to OA (Saccharomyces cerevisiae)


name: H2O + L-histidinol phosphate => L-histidinol + phosphate


name: 26S proteasome degrades HIFalpha (Sus scrofa)


name: SL (surrogate light chain) binds IgH to form pre-BCR (Mus musculus)


name: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate


name: Progesterone Activation Of CatSper (Canis familiaris)


name: FAAH2 hydrolyses AEA to AA and ETA (Drosophila melanogaster)


name: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP


name: SUMOylation of TOPORS with SUMO1 (Bos taurus)


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Rattus norvegicus)


name: BTRC:CUL1:SKP1 (SCF-beta-TrCP1) ubiquitinylates PER proteins (Homo sapiens)


name: FPRL2 receptor binds a wide range of ligands (Canis familiaris)


name: Transhomodimerization of Nectins (Mus musculus)


name: Corticotropin cleavage from POMC (Mus musculus)


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Xenopus tropicalis)


name: GGPS1 hexamer transfers IPPP to GPP (Bos taurus)


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Rattus norvegicus)


name: Expression of DUXB in the embryo (Homo sapiens)


name: androsterone dehydrogenase (A-specific) activity


name: ABC-type fatty-acyl-CoA transporter activity


name: L-isoleucine(in) + Na(+)(in) <=> L-isoleucine(out) + Na(+)(out)


name: 2 GDP + 2 H(+) => H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate


name: CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + H(+) => acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose


name: 3-oxochol-4-en-24-oyl-CoA + NAD(+) <=> 3-oxochol-4,6-dien-24-oyl-CoA + H(+) + NADH


name: 7,8-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => 8-hydroxy-7-methoxyflavone + S-adenosyl-L-methionine


name: (20S)-ginsenoside F2 + UDP-alpha-D-glucose => (20S)-ginsenoside Rd + H(+) + UDP


name: Glucosylation of collagen propeptide hydroxylysines (Canis familiaris)


name: L-threonyl-[protein] + UTP => diphosphate + uridylyl-L-threonyl-[protein]


name: protoaphin aglucone => H2O + xanthoaphin


name: Neuromedin-U receptors bind neuromedins U, S (Bos taurus)


name: 4-hydroxybenzoyl-5'-AMP + holo-[4-hydroxyphenylalkanoate synthase] <=> 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + AMP + H(+)


name: Formation of NR-MED1 Coactivator Complex (Bos taurus)


name: Phosphorylation of ZAP-70 by Lck (Rattus norvegicus)


name: 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: atropine + H2O = H(+) + tropate + tropine


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Canis familiaris)


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Rattus norvegicus)


name: H2O + L-methionine = 2-oxobutanoate + methanethiol + NH4(+)


name: a fatty acyl-AMP + diphosphate => a fatty acid + ATP + H(+)


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Danio rerio)


name: 4-methylumbelliferone beta-D-glucuronate + H2O <=> 4-methylumbelliferone + D-glucuronate


name: MAPK6 binds CCND3 (Caenorhabditis elegans)


name: TCF:Beta-catenin binds SOX proteins (Mus musculus)


name: carbon dioxide transmembrane transporter activity


name: (Z)-2-methylureidoacrylate + H2O = (Z)-2-methylaminoacrylate + carbamate + H(+)


name: CYP4F22 20-hydroxylates TrXA3 (Homo sapiens)


name: adenosine 3',5'-bisphosphate + androsterone 3alpha-sulfate + H(+) => 3'-phosphoadenylyl sulfate + androsterone


name: p-T182 MAPKAPK5 binds DNAJB1 (Gallus gallus)


name: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O => (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] => (2S)-2-hydroxynaringenin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Canis familiaris)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 bromide + 3 FADH2 + 3 O2 => (3,4,5-tribromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 3 FAD + 6 H2O


name: SHP-1 and SHP-2 bind pBTLA (Rattus norvegicus)


name: EGR2 (KROX20) activates HOXB2 expression (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Canis familiaris)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)


name: H(+) + sucrose + UDP => D-fructose + UDP-alpha-D-glucose


name: (3R)-hydroxy-(11Z,14Z,17Z)-eicosatrienoyl-CoA + NADP(+) => (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + H(+) + NADPH


name: Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (Mus musculus)


name: 17-Hydroxypregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione-17-ol (Danio rerio)


name: chorismate + H2O => (3R,4R)-3,4-dihydroxy-3,4-dihydrobenzoate + pyruvate


name: 1-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-alkyl-sn-glycero-3-phosphocholine


name: STAT1,STAT3,STAT6 bind IL13:IL13R type II (Homo sapiens)


name: IL2 gene expression is stimulated by RUNX1 and NFATC2 and repressed by FOXP3 (Homo sapiens)


name: 5-HEDH dehydrogenates 7-HDPAn-3 to 7-oxo-DPAn-3 (Homo sapiens)


name: TGFBR3(784-851) degradation (Gallus gallus)


name: eburicol + S-adenosyl-L-methionine => (24Z)-ethylidenelanosterol + H(+) + S-adenosyl-L-homocysteine


name: 3 AH2 + all-trans-neurosporene => 15-cis-phytoene + 3 A


name: Beta-catenin translocates to the nucleus (Mus musculus)


name: ATP + L-glutamate + putrescine => ADP + gamma-L-glutamylputrescine + H(+) + phosphate


name: (R)-3-hydroxybutanoate + [(3R)-hydroxybutanoate](n-1) + H(+) => [(3R)-hydroxybutanoate](n) + H2O


name: (2E)-geranyl phosphate + H2O => (2E)-geraniol + phosphate


name: H(+) + N-hydroxy-2-acetamidofluorene + NADPH => 2-acetamidofluorene + H2O + NADP(+)


name: 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA


name: MMACHC dealkylates RCbl (Xenopus tropicalis)


name: acetyl-CoA + N-terminal L-methionyl-L-alanyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-alanyl-[protein]


name: all-trans-hexaprenol + ATP => ADP + all-trans-hexaprenyl phosphate + H(+)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Homo sapiens)


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + L-glutamate => 2-oxoglutarate + [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate


name: Furin cleaves pro-prothrombin to prothrombin (Rattus norvegicus)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Dictyostelium discoideum)


name: an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose = an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: 5-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Rattus norvegicus)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Xenopus tropicalis)


name: Factor VIIIa dissociates  (Rattus norvegicus)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Sus scrofa)


name: 2-naphthyl sulfate + phenol = 2-naphthol + phenyl sulfate


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-serine


name: 2xPDXK:2xZn2+ phosphorylates PXA (Danio rerio)


name: 3 A + phytyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + 3 AH2


name: citral + H2O + NADP(+) <=> 3,7-dimethylocta-2,6-dienoate + 2 H(+) + NADPH


name: LIAS synthesizes lipoyl-GCSH (Danio rerio)


name: 2 S-adenosyl-L-methionine + uroporphyrinogen III <=> H(+) + precorrin-2 + 2 S-adenosyl-L-homocysteine


name: D-glucose + ipecoside aglycone => H2O + ipecoside


name: benzaldehyde + H(+) + NADH => benzyl alcohol + NAD(+)


name: E-selectin binds E-selectin ligand (Drosophila melanogaster)


name: a 2,3-saturated acyl-CoA + NAD(+) <=> a (2E)-enoyl-CoA + H(+) + NADH


name: Phosphorylation of pPTK2 by SRC (Homo sapiens)


name: an R-cob(III)alamin(out) + ATP + H2O => ADP + an R-cob(III)alamin(in) + H(+) + phosphate


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Caenorhabditis elegans)


name: AGK:Mg2+ phosphorylates MAG, DAG (Schizosaccharomyces pombe)


name: (R)-noradrenaline(in) + 2 H(+)(out) = (R)-noradrenaline(out) + 2 H(+)(in)


name: [thioredoxin]-disulfide + dCDP + H2O => [thioredoxin]-dithiol + CDP


name: p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Sus scrofa)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Dictyostelium discoideum)


name: Synthesis of PIP3 from PIP2 by PI3K (Rattus norvegicus)


name: ALPI dimer hydrolyses phosphate monoesters (Rattus norvegicus)


name: diphosphate + selina-4(15),7(11)-diene => (2E,6E)-farnesyl diphosphate


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> calcitriol + H2O + 2 oxidized [adrenodoxin]


name: USF1 is phosphorylated by p-MAPK14 (Gallus gallus)


name: 4 H(+) + N(6)-dimethyladenosine(1914)/N(6)-dimethyladenosine(1915) in 18S rRNA + 4 S-adenosyl-L-homocysteine => adenosine(1914)/adenosine(1915) in 18S rRNA + 4 S-adenosyl-L-methionine


name: Degradation of multiubiquitinated Cyclin B (Bos taurus)


name: HMGCR dimer reduces bHMG-CoA to MVA (Canis familiaris)


name: 2 oxidized [2Fe-2S]-[ferredoxin] + reduced coenzyme F420-(gamma-L-Glu)(n) <=> 3 H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin]


name: H(+) + NADPH + O2 + tert-butanol => 2-methylpropane-1,2-diol + H2O + NADP(+)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Rattus norvegicus)


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Drosophila melanogaster)


name: an N-acyl-L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine => a fatty acyl-[ACP] + S-adenosyl-L-methionine


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 2-(9Z-octadecenoyl)-glycerol + ATP


name: acetoacetate + H(+) + methylglyoxal => 3-hydroxyhexane-2,5-dione + CO2


name: ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Canis familiaris)


name: H2O + NAD(+) <=> ADP-D-ribose + H(+) + nicotinamide


name: CDK1:CCNB phosphorylates NEK9 (Gallus gallus)


name: (1E,2S)-2-methylbutanal oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-2-methylbutanenitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate + NADP(+) => 5alpha-dihydrotestosterone sulfate + H(+) + NADPH


name: 2 ATP + 2 H2O + hydrogenobyrinate + 2 L-glutamine <=> 2 ADP + 2 H(+) + hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 phosphate


name: Activated FGFR4 binds PLCG1 (Bos taurus)


name: ARMS is phosphorylated by active TrkA receptor (Xenopus tropicalis)


name: H(+) + NAD(+) + 2 reduced [rubredoxin] <=> NADH + 2 oxidized [rubredoxin]


name: 2-nitrobutanedioate + H2O + NADP(+) => (2S)-2-nitrosobutanedioate + H(+) + NADPH + O2


name: GDP + H(+) + mannosylinositol phosphorylphytoceramide => an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + GDP-alpha-D-mannose


name: C3b binds to cell surface (Homo sapiens)


name: USP7 deubiquitinates TP53 and counteracts MDM2 (Bos taurus)


name: acetyl-CoA + tetracosanoyl-CoA <=> 3-oxohexacosanoyl-CoA + CoA


name: glycolate(in) + H(+)(in) => glycolate(out) + H(+)(out)


name: Interaction of PECAM-1 and SHP-1 (Gallus gallus)


name: H(+) + hexan-3-one + NADPH + O2 = H2O + NADP(+) + propyl propanoate


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Drosophila melanogaster)


name: 6-amino-2-oxohexanoate + D-glutamate => 2-oxoglutarate + D-lysine


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Gallus gallus)


name: A + ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] <=> AH2 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + serpentine


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Bos taurus)


name: alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose => alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose


name: an N-acyl-D-amino acid + H2O <=> a carboxylate + a D-alpha-amino acid


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Bos taurus)


name: CFTR transits to the plasma membrane (Mus musculus)


name: alpha-D-glucosamine 6-phosphate + H2O <=> beta-D-fructose 6-phosphate + NH4(+)


name: 4-amino-4-deoxyprephenate + NAD(+) <=> 3-(4-aminophenyl)pyruvate + CO2 + H(+) + NADH


name: AGO2 cleaves passenger strand of duplex siRNA (Caenorhabditis elegans)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Rattus norvegicus)


name: SARDH:FAD oxidatively demethylates SARC to Gly (Sus scrofa)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Caenorhabditis elegans)


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Danio rerio)


name: SLC9B1/C2 exchange Na+ for H+ (Caenorhabditis elegans)


name: dTDP-alpha-D-desosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine => dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Drosophila melanogaster)


name: Interaction of integrin alphaDbeta2 with fibrin (Rattus norvegicus)


name: ALOX5 oxidises 17(S)-HDHA to 4(S)-Hp-17(S)-HDHA (Rattus norvegicus)


name: PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: HSF1 trimer translocates to the nucleus (Caenorhabditis elegans)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O <=> 2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-GMP => glycolate + GMP + H(+)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Sus scrofa)


name: SHP2 phosphatase binds CTLA-4 (Bos taurus)


name: 3-chlorocatechol + H(+) + NADH => (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+)


name: beta-ureidoisobutyrate + H2O => 3-aminoisobutyrate + NH4+ + CO2 (Dictyostelium discoideum)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Mus musculus)


name: 3'-phosphoadenylyl sulfate + a 12-hydroxyjasmonate = a 12-sulfojasmonate + adenosine 3',5'-bisphosphate + H(+)


name: ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 5,20-dihydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Bos taurus)


name: PIAS1,3 SUMOylates NR5A1 with SUMO2 (Gallus gallus)


name: an oxidized flavin + 2 H(+) + NADH => a reduced flavin + NAD(+)


name: Scaffolding protein CKA binds BSK and phosphorylated HEP kinases (Drosophila melanogaster)


name: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate


name: NH4(+) + pyrazine-2-carboxylate => H2O + pyrazinamide


name: lactose + H2O => D-glucose + D-galactose (Gallus gallus)


name: FeHM dissociates from MetHb (Danio rerio)


name: RNF152 polyubiquitinates RRAGA (Mus musculus)


name: Transport of MHC II:Ii complex to plasma membrane (Sus scrofa)


name: PLK1 phosphorylates GORASP1 (Sus scrofa)


name: p-DAPP1 (p-BAM32) binds PLCG2 (Schizosaccharomyces pombe)


name: oxidoreductase activity, acting on diphenols and related substances as donors


name: "Acting on diphenols and related substances as donors"


name: ATP + beta-alanine + L-histidine => ADP + carnosine + H(+) + phosphate


name: botC HC transports botC LC from target cell synaptic vesicle membrane to cytosol (Homo sapiens)


name: HSF1 trimer translocates to the nucleus (Bos taurus)


name: CHIT1 hydrolyses CHIT to 3xADGP (Drosophila melanogaster)


name: (4S)-limonene + A + H2O <=> (4S)-perillyl alcohol + AH2


name: [(1->4)-alpha-D-galacturonosyl](n) + H2O => [(1->4)-alpha-D-galacturonosyl](n-2) + alpha-D-galacturonosyl-(1->4)-D-galacturonate


name: D-galactaro-1,4-lactone => 5-dehydro-4-deoxy-D-glucarate + H(+)


name: KDM5A-D demethylate Me3K5-histone H3 (Saccharomyces cerevisiae)


name: (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-dihydrotricetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of the SET1B complex (Dictyostelium discoideum)


name: NICD4 traffics to the nucleus (Rattus norvegicus)


name: 1-deoxy-D-xylulose + ATP => 1-deoxy-D-xylulose 5-phosphate + ADP + H(+)


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Rattus norvegicus)


name: a (3S)-3-hydroxyacyl-CoA => a (2E)-enoyl-CoA + H2O


name: Binding of GRB2:GAB1 complex to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Bos taurus)


name: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+)


name: PHGDH tetramer dehydrogenates 3PG (Drosophila melanogaster)


name: an aldehyde + H(+) + NADPH => a primary alcohol + NADP(+)


name: cyanidin 3-O-beta-D-glucoside + H(+) + UDP => cyanidin + UDP-alpha-D-glucose


name: LUM (lumican) binds integrin alpha2beta1 (Bos taurus)


name: VEGFA-165 dimer binds VEGFA inhibitors (Gallus gallus)


name: FADH2-C4alpha-hydroperoxide + H(+) + NADH + rifamycin SV => FADH2 + H2O + NAD(+) + rifamycin SV hemiaminal


name: (-)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+) => (-)-dehydrodiconiferyl acid + 2 a quinone + H2O


name: RHOT2 binds effectors at the mitochondrial outer membrane (Saccharomyces cerevisiae)


name: 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 = CO2 + grixazone B + 4 H2O


name: divinyl chlorophyllide a 8-vinyl-reductase activity


name: 6-carboxyhexanoyl-CoA + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + CoA


name: FAHD1 dimer hydrolyses OA to PYR (Xenopus tropicalis)


name: GPRC6A can bind L-alpha amino acids and calcium (Danio rerio)


name: a cis-3-alkyl-4-alkyloxetan-2-one = a cis-alkene + CO2


name: Receptor CXCR6 binds CXCL16 ligand (Sus scrofa)


name: Caspase mediated cleavage of APC (Mus musculus)


name: 2'-deoxycytidine + UTP => dCMP + H(+) + UDP


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Drosophila melanogaster)


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Sus scrofa)


name: histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate (Homo sapiens)


name: Factor IIa inhibitors (compounds) binds IIa (Bos taurus)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Bos taurus)


name: 1,6-dihydro-beta-NADP + H(+) + O2 <=> H2O2 + NADP(+)


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Rattus norvegicus)


name: ALOX5 oxidises DHA to 7-HDHA (Rattus norvegicus)


name: 3-hydroxypyruvate + H2O2 + NH4(+) => D-serine + H2O + O2


name: p-PKR dimer phosphorylates TP53 tetramer (Drosophila melanogaster)


name: 3-(2,3-dihydroxyphenyl)propanoate + O2 = (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate + H(+)


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Sus scrofa)


name: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => calcitetrol + H2O + 2 oxidized [adrenodoxin]


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Rattus norvegicus)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Bos taurus)


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) => 5,6,7,8-tetrahydromethanopterin + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: 3-oxo-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Gallus gallus)


name: an L-amino acid tripeptide(in) + H(+)(in) => an L-amino acid tripeptide(out) + H(+)(out)


name: 3-hydroxyanthranilate + O2 <=> (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde


name: MMACHC decyanates CNCbl (Xenopus tropicalis)


name: 2-aminobenzoyl-AMP + CoA <=> AMP + anthraniloyl-CoA + H(+)


name: (2R,3R)-2,3-dihydrogossypetin + H2O + NAD(+) => (2R,3R)-dihydroquercetin + H(+) + NADH + O2


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Mus musculus)


name: myricetin 3-O-alpha-L-rhamnoside + UDP-alpha-D-glucose = H(+) + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + UDP


name: 2 7-demethylsiderin + NADPH + O2 => 2 H2O + NADP(+) + orlandin


name: (5S,9S,10S)-drim-7-en-11-ol + O2 + reduced [NADPH--hemoprotein reductase] => (5S,10S)-(9R)-7-drimene-11,12-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Canis familiaris)


name: (2S)-3-methyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]butanoate + H(+) + H2O = 2-dehydro-D-glucose + L-valine


name: A + Fe(II)-heme o + H2O = AH2 + Fe(II)-heme i


name: dodecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(2-oxotridecyl)pyran-2-one + 3 CO2 + 4 CoA


name: SLC51A:SLC51B transports bile salts from cytosol to extracellular region (Sus scrofa)


name: BIL binds GSTA1, FABP1 (Canis familiaris)


name: HCFC1, HCFC2 bind the MLL1:MEN1 complex (Bos taurus)


name: Formation of histidino-hydroxylysinonorleucine cross-links (Sus scrofa)


name: CO2 + isopentenyl phosphate + phosphate => (R)-3,5-bisphosphomevalonate + H(+)


name: (11R)-methyl carlactonoate + 2-oxoglutarate + O2 => (11R)-hydroxymethyl carlactonoate + CO2 + succinate


name: p-Y389,400-RUFY1 binds PI3P (Bos taurus)


name: ADP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H(+) + phosphate => ATP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine


name: PRMT6 methylates histone H2A arginine-30 (H2AR29) (Danio rerio)


name: ROS oxidize thioredoxin and activate MAP3K5 (Bos taurus)


name: AKT phosphorylates caspase-9 (Danio rerio)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Canis familiaris)


name: (R,S)-butane-2,3-diol + NAD(+) = (S)-acetoin + H(+) + NADH


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Canis familiaris)


name: L-cystine(out) + Na(+)(out) => L-cystine(in) + Na(+)(in)


name: allyl alcohol + NADP(+) => acrolein + H(+) + NADPH


name: EBP isomerizes ZYMSTNL to LTHSOL (Homo sapiens)


name: ATP + H(+) + L-lysine <=> diphosphate + L-lysyl-5'-AMP


name: p-S585-IL3RB binds 14-3-3 proteins (Gallus gallus)


name: (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + H2O + NAD(+) <=> (E)-2-((N-methylformamido) methylene)succinate + 3 H(+) + NADH


name: PKC binds active G alpha (z) (Homo sapiens)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Mus musculus)


name: glutathione(in) + urate(out) <=> glutathione(out) + urate(in)


name: Unwinding DNA for the nascent transcript (Bos taurus)


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)


name: RAC1:GTP binds NOX1 complex (Bos taurus)


name: dAMP + H2O = 2'-deoxyadenosine + phosphate


name: Trafficking of GluR2-containing AMPA receptors to synapse (Bos taurus)


name: 1-hexanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+)


name: (11Z)-eicosenamide + H2O => (11Z)-eicosenoate + NH4(+)


name: TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Sus scrofa)


name: chenodeoxycholate + glycine <=> glycochenodeoxycholate + H2O


name: RUNX1 binds intron 1 of IL2RA (CD25) gene (Homo sapiens)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Rattus norvegicus)


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Mus musculus)


name: NR1H2,3 binds the PLTP gene (Homo sapiens)


name: glutamine + H2O => glutamate + NH4+ [GLS] (Canis familiaris)


name: [sulfur carrier]-SH + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + S-adenosyl-L-methionine => [sulfur carrier]-H + H(+) + L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + S-adenosyl-L-homocysteine


name: ATP + H(+) + octanoate <=> diphosphate + octanoyl-AMP


name: a very long-chain fatty acid + ATP + CoA <=> a very long-chain fatty acyl-CoA + AMP + diphosphate


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Mus musculus)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Bos taurus)


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Caenorhabditis elegans)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Drosophila melanogaster)


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Rattus norvegicus)


name: Activated FGFR4 binds FRS3 (Danio rerio)


name: IL35 binds IL12RB2:IL12RB2 receptor (Sus scrofa)


name: 5,6,7,8-tetrahydromethanopterin + ATP + L-glutamate <=> 5,6,7,8-tetrahydrosarcinapterin + ADP + H(+) + phosphate


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Drosophila melanogaster)


name: ABCF1 binds EIF2 (Saccharomyces cerevisiae)


name: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate + pyruvate => (2S)-2-amino-4-deoxychorismate + H2O


name: 2 5'-dehydroinosine + O2 => 2 9-riburonosylhypoxanthine + 2 H(+)


name: SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors (Homo sapiens)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (2E)-decenoyl-CoA + NADP(+) = (2E,4E)-decadienoyl-CoA + H(+) + NADPH


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Mus musculus)


name: a long-chain fatty acyl-[ACP] + H(+) + NADH => a long-chain fatty aldehyde + holo-[ACP] + NAD(+)


name: a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate


name: DHX36 or DHX9 binds MyD88 (Canis familiaris)


name: 10-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: p-PLINs translocate from lipid droplet surface to cytosol (Homo sapiens)


name: MET phosphorylates STAT3 (Xenopus tropicalis)


name: atRAL is reduced to atROL (Canis familiaris)


name: a 2-oxocarboxylate + H(+) + NADH + NH4(+) => an L-alpha-amino acid + H2O + NAD(+)


name: Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Drosophila melanogaster)


name: KRAB-ZNF / KAP Interaction (Rattus norvegicus)


name: (2E)-hexenoyl-[ACP] + H(+) + NADPH = hexanoyl-[ACP] + NADP(+)


name: (9Z,12Z)-octadecadien-1-ol + 1-hexadecanoylglycerone 3-phosphate => 1-O-(9Z,12Z)-octadecadienylglycerone 3-phosphate + H(+) + hexadecanoate


name: EPHB phosphorylates TIAM1 (Mus musculus)


name: 2-phenylacetate + ATP + CoA => AMP + diphosphate + phenylacetyl-CoA


name: (22E)-3-oxochola-4,22-dien-24-oyl-CoA + AH2 => 3-oxochol-4-en-24-oyl-CoA + A


name: (6S)-5,6,7,8-tetrahydrofolate + N,N-dimethylglycine + O2 = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O2 + sarcosine


name: Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 (Drosophila melanogaster)


name: (2Z,6E)-farnesyl diphosphate => (Z)-gamma-bisabolene + diphosphate


name: HDAC6 deacetylates microtubules (Canis familiaris)


name: (E)-caffeoyl-AMP + CoA => (E)-caffeoyl-CoA + AMP + H(+)


name: Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) (Rattus norvegicus)


name: IFN alpha/beta binds to IFNAR2 (Homo sapiens)


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Rattus norvegicus)


name: NUMB:ITCH ubiquitinates GLI1 (Sus scrofa)


name: 4 (R)-methylmalonyl-CoA + 12 H(+) + long-chain fatty acyl-[mycocerosate synthase] + 8 NADPH => 4 CO2 + 4 CoA + 4 H2O + 8 NADP(+) + tetramethylated-mycocerosoyl-[mycocerosate synthase]


name: Activation of EPACs by cAMP (Bos taurus)


name: ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol (Homo sapiens)


name: Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Bos taurus)


name: FMN + O2 => 8-demethyl-8-formylriboflavin 5'-phosphate + H2O


name: FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)


name: pre-VLDL translocates from RER membrane to SER lumen (Canis familiaris)


name: 2-phenylethanol + benzoyl-CoA = CoA + phenethyl benzoate


name: (R)-carnitine(out) + glycine betaine(in) => (R)-carnitine(in) + glycine betaine(out)


name: MATEs mediate extrusion of xenobiotics (Danio rerio)


name: Homodimerization of ERBB4 (Drosophila melanogaster)


name: NMRK2 phosphorylates NAR to yield NAMN (Mus musculus)


name: structural constituent of presynaptic active zone


name: IL6R binds IL6R inhibitors (Homo sapiens)


name: beta-D-galactose + D-glucose => H2O + lactose


name: ATP + H2O + leukotriene C4(in) = ADP + H(+) + leukotriene C4(out) + phosphate


name: glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Sus scrofa)


name: SeMet is converted to AdoSeMet by MAT (Canis familiaris)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + 3 isopentenyl diphosphate <=> all-trans-heptaprenyl diphosphate + 3 diphosphate


name: PalmS-ESRs:CAVs translocate to plasma membrane (Rattus norvegicus)


name: ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate


name: Ubiquitinated TP53 translocates to the cytosol (Mus musculus)


name: 4-hydroxy-2-oxoheptanedioate => pyruvate + succinate semialdehyde


name: 2 ADP + 2 H(+) + hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 phosphate => 2 ATP + 2 H2O + hydrogenobyrinate + 2 L-glutamine


name: vitamin-K-epoxide reductase (warfarin-insensitive) activity


name: ULK1 Translocates to the mitochondria (Drosophila melanogaster)


name: SHP2 dephosphorylates Tyr 992 on EGFR (Mus musculus)


name: (6E)-8-methylnon-6-enoyl-CoA + vanillylamine = capsaicin + CoA + H(+)


name: Interaction of particulate antigens with dendritic cell receptors (Drosophila melanogaster)


name: SPP1 (osteopontin) binds CD44 (Rattus norvegicus)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Caenorhabditis elegans)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Bos taurus)


name: H(+) + H2O + horhammericine + oxidized [NADPH--hemoprotein reductase] => lochnericine + O2 + reduced [NADPH--hemoprotein reductase]


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Gallus gallus)


name: UBA1 adenylates ubiquitin in the cytosol (Sus scrofa)


name: 2-phenylethanol + 2 Fe(III)-[cytochrome c] = 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Sus scrofa)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] <=> 1-[(9R,10S)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a ribonucleoside 5'-diphosphate + ATP => a ribonucleoside 5'-triphosphate + ADP


name: CYCS:APAF1 binds procaspase-9 (Rattus norvegicus)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Sus scrofa)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline => 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: H2O + N(6)-hydroxy-L-lysine + NADP(+) => L-lysine + NADPH + O2


name: SREBP1A,2 binds the CYP51A1 promoter (Homo sapiens)


name: hydrolase activity, hydrolyzing O-glycosyl compounds


name: fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP (Gallus gallus)


name: Interleukin-35 translocates from the ER lumen to the extracellular region (Sus scrofa)


name: GSDME (1-270) binds cardiolipin (Rattus norvegicus)


name: citrate(out) + maleate(in) => citrate(in) + maleate(out)


name: IL3 stimulation induces Vav binding to Tec kinase (Xenopus tropicalis)


name: DLAT trimer transfers acetyl to CoA (Drosophila melanogaster)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Drosophila melanogaster)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Caenorhabditis elegans)


name: Dopa is decarboxylated to dopamine (Sus scrofa)


name: 4 5'-deoxyadenosine + 2 A + glycerol dibiphytanyl glycerol tetraether + 4 H(+) + 4 L-methionine => 2 AH2 + 2 archaeol + 4 S-adenosyl-L-methionine


name: glyoxylate + oxaloacetate => 3-oxalomalate


name: IL20 binds IL20RA:JAK1:IL20RB (Canis familiaris)


name: RAC1,RAC2,RHOG activate PI3K (Gallus gallus)


name: an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Bos taurus)


name: L-glutamine(in) + L-methionine(out) + Na(+)(out) => L-glutamine(out) + L-methionine(in) + Na(+)(in)


name: Interaction of Tie2 with Ang2 (Homo sapiens)


name: sphinga-(4E,8E)-dienine + tetracosanoyl-CoA <=> CoA + H(+) + N-tetracosanoylsphinga-(4E,8E)-dienine


name: Autophosphorylation of SRC (Homo sapiens)


name: (S)-2,3-diaminopropanoate + H(+) + H2O <=> 2 NH4(+) + pyruvate


name: galactarate(in) + H(+)(in) => galactarate(out) + H(+)(out)


name: Activation of Ca-permeable Kainate receptors (Gallus gallus)


name: H2O + hexanal + O2 => H(+) + H2O2 + hexanoate


name: NEU1 hydrolyses Neu5Ac from glycoconjugates (Sus scrofa)


name: HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Rattus norvegicus)


name: ATP + N-acetyl-D-galactosamine = ADP + H(+) + N-acetyl-D-galactosamine 6-phosphate


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Caenorhabditis elegans)


name: CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Sus scrofa)


name: 7-dehydrocholesterol + NADP(+) <=> 7-dehydrodesmosterol + H(+) + NADPH


name: glycylglycyl-L-isoleucine(out) + H(+)(out) <=> glycylglycyl-L-isoleucine(in) + H(+)(in)


name: TBC1D7 binds the TSC1-TSC2 complex (Homo sapiens)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + a triacylglycerol => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacylglycerol


name: dimethylallyl diphosphate + 4 isopentenyl diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADPH => all-trans-lycopaoctaene + 2 diphosphate + NADP(+)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Mus musculus)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O <=> acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative


name: (2E)-decenoyl-CoA + H2O <=> 3-hydroxydecanoyl-CoA


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Rattus norvegicus)


name: CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 (Plasmodium falciparum)


name: (cis-prenyl)n-diphosphate + isopentenyl diphosphate => (cis-prenyl)(n+1)-diphosphate + diphosphate


name: SPHK2 binds SPHK2 inhibitors (Dictyostelium discoideum)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Mus musculus)


name: H2O + L-seryl-tRNA(Ser) <=> L-serine + tRNA(Ser)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Homo sapiens)


name: H(+) + H2O + L-tyrosine + O2 <=> (4-hydroxyphenyl)acetaldehyde + CO2 + H2O2 + NH4(+)


name: (2E,6E)-farnesyl diphosphate + H2O = 5-hydroxy-alpha-gurjunene + diphosphate


name: (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate <=> 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate => CO2 + diphosphate + nicotinate beta-D-ribonucleotide


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Gallus gallus)


name: CAD hexamer transforms L-Gln to CAP (Xenopus tropicalis)


name: (2R)-2-hydroxyoctadecanoyl-CoA = formyl-CoA + heptadecanal


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Rattus norvegicus)


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate => 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + ATP + CoA


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Gallus gallus)


name: Thrombin-activated PARs activate Gq (Gallus gallus)


name: hexanoyl-CoA + NAD(+) = (2E)-hexenoyl-CoA + H(+) + NADH


name: 2-naphthol + 3'-phosphoadenylyl sulfate <=> 2-naphthyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Trimerization of HSF1 in the nucleus (Gallus gallus)


name: ESR1 binds to TFF1 gene promoter (Sus scrofa)


name: a 2'-deoxyribonucleoside + ATP <=> a 2'-deoxyribonucleoside 5'-phosphate + ADP + H(+)


name: 2-oxoglutarate + L-valine <=> 3-methyl-2-oxobutanoate + L-glutamate


name: IDO2 dioxygenates L-Trp to NFK (Danio rerio)


name: Processing of SCF isoform 1 (Sus scrofa)


name: p-T182 MAPKAPK5 binds DNAJB1 (Rattus norvegicus)


name: Na(+)(in) + uridine(in) => Na(+)(out) + uridine(out)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Caenorhabditis elegans)


name: chloride(in) + L-leucine(in) + 2 Na(+)(in) => chloride(out) + L-leucine(out) + 2 Na(+)(out)


name: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 5,20-dihydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PI3K associates with phosphorylated GAB2 (Canis familiaris)


name: Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA (Rattus norvegicus)


name: ALD3A1 oxidises 4HPCP to CXPA (Dictyostelium discoideum)


name: (2E)-geranyl diphosphate = alpha-terpinene + diphosphate


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Mus musculus)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Plasmodium falciparum)


name: 3-methoxy-4-hydroxy-5-all-trans-octaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine => 3,4-dihydroxy-5-all-trans-octaprenylbenzoate + S-adenosyl-L-methionine


name: Activated FGFR4:p-FRS bind to PPTN11 (Mus musculus)


name: Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)


name: 16beta,17beta-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP => 16beta,17beta-estriol + UDP-alpha-D-glucuronate


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-glycerol = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA


name: MRRF binds 55S ribosome:mRNA:tRNA (Bos taurus)


name: PTP1B dephosphorylates JAK2 (Homo sapiens)


name: KAT6A acetylates TP53 (Canis familiaris)


name: GAB1 phosphorylation by EGFR kinase (Xenopus tropicalis)


name: ABCC1 transports BIL from cytosol to extracellular region (blood) (Saccharomyces cerevisiae)


name: 3-methyl-2-oxobutanoate + CoA + NAD(+) => 2-methylpropanoyl-CoA + CO2 + NADH


name: (2R)-3-phosphoglycerate + GDP-D-glucose = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)


name: Intrinsic nucleotide exchange on RAS (Bos taurus)


name: CHSY1 transfers GalNAc to chondroitin (Bos taurus)


name: PLC beta-mediated PIP2 hydrolysis (Bos taurus)


name: H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH


name: Autoproteolytic cleavage of Hh precursors (Gallus gallus)


name: Duplex miRNA is loaded into Argonaute (Mus musculus)


name: (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone A


name: MBTPS1 (S1P) cleaves CREB3L3 (Mus musculus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + reduced [electron-transfer flavoprotein]


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Homo sapiens)


name: Receptor ACKR2 binds most inflammatory CC chemokines (Mus musculus)


name: a 1,2-diacyl-sn-glycerol + CTP => a 1,2-diacyl-sn-glycero-3-phosphate + CDP + H(+)


name: POLK incorporates dNMP opposite to damaged DNA base (Schizosaccharomyces pombe)


name: Aquaporins passively transport urea into cells (Gallus gallus)


name: a primary alcohol + 2 Fe(III)-[cytochrome c] <=> an aldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: NME1,2 hexamers phosphorylate RBV-DP (Mus musculus)


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Homo sapiens)


name: IRAK1 phosphorylates Pellino (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA


name: D-serine(in) + L-alanine(out) + Na(+)(out) = D-serine(out) + L-alanine(in) + Na(+)(in)


name: Cross-linking of FCGRIIIA with IgG-coated Ag (Gallus gallus)


name: ethanol + o-quinone methide => hydroxyclavatol ethyl ether


name: a ganglioside GM2 + H2O => a ganglioside GM3 + N-acetyl-beta-D-galactosamine


name: AFG3L2 binds mitochondrial inner membrane proteins (Canis familiaris)


name: TAK1 is activated within the TAK1 complex (Mus musculus)


name: a 7(1)-hydroxybacteriochlorophyllide d + H2O + S-adenosyl-L-methionine = 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide d + H(+) + L-methionine


name: TRIM21 ubiquitinates SQSTM1 (Homo sapiens)


name: PKM dephosphorylates PEP to PYR (Saccharomyces cerevisiae)


name: Interleukin-5 is a homodimer (Sus scrofa)


name: PKM dephosphorylates PEP to PYR (Rattus norvegicus)


name: isorhamnetin + S-adenosyl-L-methionine => 3,3'-O-dimethylquercetin + H(+) + S-adenosyl-L-homocysteine


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Sus scrofa)


name: botG LC cleaves target cell VAMP2 (Homo sapiens)


name: ADP + glycyl-L-glutamyl-[protein] + H(+) + phosphate => ATP + glycine + L-glutamyl-[protein]


name: Formation of meiotic single-stranded DNA invasion complex (Homo sapiens)


name: p-S256-Aquaporin-2 passively transports water into cell (Homo sapiens)


name: DLST transfers glutaryl to CoA (Dictyostelium discoideum)


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Mus musculus)


name: ATP + H2O + Mn(2+)(out) <=> ADP + H(+) + Mn(2+)(in) + phosphate


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Mus musculus)


name: A + all-trans-phytofluene => AH2 + all-trans-zeta-carotene


name: (2E,6E)-farnesol + NADP(+) <=> (2E,6E)-farnesal + H(+) + NADPH


name: (9Z)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: STAT3 binds activated MET receptor (Sus scrofa)


name: Translocation of PLC-gamma1 to PIP2 (Homo sapiens)


name: ATP + H2O + levoglucosan <=> ADP + D-glucose 6-phosphate + H(+)


name: 5alpha-androstan-3,17-dione + H(+) + NADH => androsterone + NAD(+)


name: TAT deaminates tyrosine (Rattus norvegicus)


name: (3,5-dihydroxyphenyl)acetyl-CoA + O2 <=> 2-(3,5-dihydroxyphenyl)-2-oxoacetate + CoA + H(+)


name: Dissociation of CaM and CAMK2 autophosphorylation (Drosophila melanogaster)


name: Formation of Cyclin E:Cdk2 complexes (Mus musculus)


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Rattus norvegicus)


name: 3-O-[N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->6)-N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + H(+) + UDP


name: LIAS synthesizes lipoyl-GCSH (Drosophila melanogaster)


name: chloride + FADH2 + L-tryptophan + O2 => 6-chloro-L-tryptophan + FAD + 2 H2O


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Dictyostelium discoideum)


name: arsenite + H2O + 2 oxidized [azurin] => arsenate + 3 H(+) + 2 reduced [azurin]


name: PRODH oxidises L-Pro to 1PYR-5COOH (Rattus norvegicus)


name: TOPORS SUMOylates IKBKE with SUMO1 (Rattus norvegicus)


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Xenopus tropicalis)


name: bilirubin IXalpha bis-beta-D-glucuronoside(out) <=> bilirubin IXalpha bis-beta-D-glucuronoside(in)


name: guanosine(in) + H(+)(in) <=> guanosine(out) + H(+)(out)


name: (S)-dihydroorotate + fumarate => orotate + succinate


name: AXL autophosphorylates on Y779 and Y821 (Bos taurus)


name: a quinol + dihydroxyacetone phosphate => a quinone + sn-glycerol 3-phosphate


name: Degradation of MHC I Complex (Homo sapiens)


name: 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O => 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Sus scrofa)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Caenorhabditis elegans)


name: prostaglandin H2 = (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde


name: A + AMP + diphosphate + ilicicolin B => AH2 + ATP + ilicicolinate B


name: (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine


name: TNFSF18 binds TNFRSF18 (Canis familiaris)


name: MDH2 dimer dehydrogenates MAL (Xenopus tropicalis)


name: [DsrC protein]-trisulfide + 3 H2O + NAD(+) <=> [DsrC protein]-dithiol + 3 H(+) + NADH + sulfite


name: Formation of soluble VTN:C5b-C9  (Canis familiaris)


name: TRIP11:IFT20 dissociates (Caenorhabditis elegans)


name: H2O + octanoyl-CoA = adenosine 3',5'-bisphosphate + 2 H(+) + S-octanoyl-4'-phosphopantetheine


name: SUMOylation of HIPK2 with SUMO1 (Mus musculus)


name: abacavir [extracellular] => abacavir [cytosol] (Xenopus tropicalis)


name: GP1b-IX-V binds 14-3-3-zeta (Sus scrofa)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Caenorhabditis elegans)


name: H(+) + N(3)-methyluridine in 25S rRNA + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine in 25S rRNA


name: SARS-CoV-1 SUMO1-K62-p-S177-N dimer binds to EEF1A1 (Homo sapiens)


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Drosophila melanogaster)


name: adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O + 4 L-glutamine => adenosylcob(III)yrate + 4 ADP + 4 H(+) + 4 L-glutamate + 4 phosphate


name: a ganglioside Ac-O-7-GD1b(2-) = a ganglioside Ac-O-8-GD1b


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Rattus norvegicus)


name: L-alanine + taurocholate <=> L-alanocholate + taurine


name: STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Canis familiaris)


name: 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H2O => chloride + 2 H(+) + maleylacetate


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Mus musculus)


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Canis familiaris)


name: ATP + CoA + octadecanoate => AMP + diphosphate + octadecanoyl-CoA


name: H(+) + oxidized [electron-transfer flavoprotein] + tricosanoyl-CoA = (2E)-tricosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: (S)-2-ureidoglycine + H2O => glyoxylate + NH4(+) + urea


name: ATP + 12 H(+) + L-leucine + 8 malonyl-CoA + 9 NADPH + 4 S-adenosyl-L-methionine = (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 8 CO2 + 8 CoA + diphosphate + 7 H2O + 9 NADP(+) + 4 S-adenosyl-L-homocysteine


name: L-arginine(in) + L-cystine(out) => L-arginine(out) + L-cystine(in)


name: 3 H(+) + 3 malonyl-CoA + octadecanoyl-CoA <=> 4-hydroxy-6-(2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: H(+) + NADH + S-nitrosoglutathione => NAD(+) + S-(hydroxysulfenamide)glutathione


name: H(+) + NADPH + prostaglandin E1 = NADP(+) + prostaglandin F1


name: GLYCTK phosphorylates DGA to 3PDGA (Drosophila melanogaster)


name: Slo3 Potassium Transport (Caenorhabditis elegans)


name: 5-guanidino-2-oxopentanoate + H(+) <=> 4-guanidinobutanal + CO2


name: The Ligand:GPCR:Gz complex dissociates (Canis familiaris)


name: n H(+)(out) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanine(out) => n H(+)(in) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate-D-alanine(in)


name: NRXNs bind NLGNs (Caenorhabditis elegans)


name: carcinine + H2O = beta-alanine + histamine


name: USP16,USP21 deubiquitinate Histone H2A (Xenopus tropicalis)


name: 3-dehydro-6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 3-dehydroteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: sucrose + H2O => glucose + fructose (Caenorhabditis elegans)


name: (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH => (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+)


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Bos taurus)


name: Autocatalytic phosphorylation of FGFR4 (Drosophila melanogaster)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Bos taurus)


name: L-aspartate(in) + L-glutamine(out) <=> L-aspartate(out) + L-glutamine(in)


name: D-arabinitol + NADP(+) => D-xylulose + H(+) + NADPH


name: acetyl-CoA + GDP-alpha-D-perosamine = CoA + GDP-N-acetyl-alpha-D-perosamine + H(+)


name: an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NADP(+) => 4-methylcatechol + CO2 + NADPH


name: a ribonucleoside 5'-phosphate + phosphate => a ribonucleoside 3',5'-bisphosphate + H2O


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Canis familiaris)


name: MAP2Ks phosphorylate MAPKs (Gallus gallus)


name: choline + phosphate => H2O + phosphocholine


name: 2 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine = 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Canis familiaris)


name: H2O + O2 + propane-1,3-diamine = 3-aminopropanal + H2O2 + NH4(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-guanosine) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: an alpha-mannosylinositol-1-phosphoceramide + H2O <=> a D-mannosyl-alpha-1->6-inositol-1-phosphate + an N-acyl-sphingoid base + H(+)


name: 2 Na(+)(out) + taurohyodeoxycholate(out) = 2 Na(+)(in) + taurohyodeoxycholate(in)


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Rattus norvegicus)


name: TREM,CD300 binds lipids (Canis familiaris)


name: 3-(4-hydroxyphenyl)pyruvate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + L-tyrosine


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 2 Fe(III)-[cytochrome b5] + 2 H2O + N-acyl-(4E,8E,10E)-sphingatrienine


name: a medium-chain 3-oxoacyl-CoA + H(+) + NADH => a medium-chain (3S)-3-hydroxyacyl-CoA + NAD(+)


name: (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + H(+) = (8Z,11Z,14Z)-heptadecatrienal + CO2 + H2O


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: (2E,6E)-farnesyl diphosphate + H2O <=> (-)-alpha-acorenol + diphosphate


name: [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + ATP + H(+) <=> [sulfur-carrier protein ThiS]-C-terminal Gly-Gly-AMP + diphosphate


name: all-trans-5,6-epoxyretinoyl-1-O-(beta-D-glucuronate) + UDP => all-trans-5,6-epoxyretinoate + UDP-alpha-D-glucuronate


name: CDK6 inhibitors bind CDK6 (Canis familiaris)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Gallus gallus)


name: 2-thio-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + H(+) + L-methionine => [sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + S-adenosyl-L-methionine


name: 4-methylaminobutyrate oxidase (demethylating) activity


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Homo sapiens)


name: DCP1-DCP2 complex decaps mRNA (Sus scrofa)


name: AMP + diphosphate + H(+) + N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine => ATP + citrate + N(6)-acetyl-N(6)-hydroxy-L-lysine


name: a beta-D-galactoside + CMP-N-acetyl-beta-neuraminate => an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP


name: H2O + zearalenone => H(+) + hydrolyzed zearalenone


name: Fructose 2,6-bisphosphate is hydrolyzed to form fructose-6-phosphate and orthophosphate (Dictyostelium discoideum)


name: SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane (Sus scrofa)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Canis familiaris)


name: (2R)-3-sulfolactate => H(+) + pyruvate + sulfite


name: 2-oxoglutarate + L-phenylalanine => 3-phenylpyruvate + L-glutamate


name: 2-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + glycerol + H(+)


name: 1D-myo-inositol 1,4,5-trisphosphate + 2 ATP <=> 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 2 ADP + 2 H(+)


name: p-S MAPK6,4 binds MAPKAPK5 (Mus musculus)


name: (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate + H2O => 2-amino-2-deoxy-D-gluconate


name: ion channel regulator activity involved in G protein-coupled receptor signaling pathway


name: Translocation of DPA to the ER (Homo sapiens)


name: NCOA1(868-1441) binds PAX3(1-319) (Homo sapiens)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Schizosaccharomyces pombe)


name: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + H2O <=> L-threonyl-[protein] + N-acetyl-D-glucosamine


name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] (Homo sapiens)


name: histidine => urocanate + NH4+ (Canis familiaris)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Caenorhabditis elegans)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Mus musculus)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Gallus gallus)


name: arginine + H2O => ornithine + urea [ARG1] (Rattus norvegicus)


name: hexanal + NADP(+) => (E)-hex-2-enal + H(+) + NADPH


name: H(+)(in) + L-tyrosylglycine(in) => H(+)(out) + L-tyrosylglycine(out)


name: cinnamyl alcohol + 2 Fe(III)-[cytochrome c] <=> cinnamaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: a short-chain (3R)-hydroxy fatty acyl-CoA + NAD(+) <=> a short-chain 3-oxoacyl-CoA + H(+) + NADH


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Bos taurus)


name: a 5'-end triphospho-guanosine in mRNA + H2O <=> a 5'-end diphospho-guanosine in mRNA + H(+) + phosphate


name: 6-demethylmitomycin B + S-adenosyl-L-methionine = mitomycin B + S-adenosyl-L-homocysteine


name: 5'-triphosphoadenylyl-(2'->5')-adenosine + H2O => AMP + ATP + H(+)


name: p85 regulatory unit of PI3K binds p-6Y-SYK (Rattus norvegicus)


name: acetate + cytidine + H(+) => H2O + N(4)-acetylcytidine


name: (3R)-3-hydroxy-D-aspartate => glycine + glyoxylate


name: Trimerization of cytosolic HSF1 (Caenorhabditis elegans)


name: protoporphyrin IX + Fe++ => heme + 2 H+ (Gallus gallus)


name: 2-oxooctadecanoate + H(+) + NADH => (R)-2-hydroxyoctadecanoate + NAD(+)


name: Aquaporin-1 passively transports water out of cell (Dictyostelium discoideum)


name: dGTP(out) + UTP(in) = dGTP(in) + UTP(out)


name: hexadecanoyl-CoA + N-terminal L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester => CoA + H(+) + N-terminal N-hexadecanoyl-L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester


name: Truncated AMER1 mutants destabilize the destruction complex (Homo sapiens)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + tetradecanoyl-CoA = (9Z)-tetradecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: TXLNA (IL14) binds syntaxin3 (Dictyostelium discoideum)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)


name: SORD oxidizes D-sorbitol to Fru (Saccharomyces cerevisiae)


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Mus musculus)


name: S-adenosyl-L-methionine + uridine(47) in tRNA(Phe) <=> 3-[(3S)-3-amino-3-carboxypropyl]uridine(47) in tRNA(Phe) + H(+) + S-methyl-5'-thioadenosine


name: NaS1 co-transports sulphate and a sodium ion (Caenorhabditis elegans)


name: CyP60 chaperones Basigin (Canis familiaris)


name: α1-antagonists bind ADRA1A,B,D (Mus musculus)


name: RNA demethylases demethylate N6-methyladenosine RNA (Bos taurus)


name: DLD dimer dehydrogenates dihydrolipoyl (Xenopus tropicalis)


name: a globoside Gb3Cer (d18:1(4E)) + H2O => a fatty acid + a lysoGb3(d18:1(4E))


name: (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O <=> 18S-resolvin E1


name: Endocytosis of TRAM (TICAM2) (Bos taurus)


name: The receptor:G-protein complex dissociates (Homo sapiens)


name: Mad1 binds kinetochore (Rattus norvegicus)


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Bos taurus)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Xenopus tropicalis)


name: AKAP8L binds MLL2 complex (Mus musculus)


name: Activation of STAT5a/b by JAK2 (Mus musculus)


name: lithocholate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + hyodeoxycholate + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Mus musculus)


name: XDH oxidizes xanthine to form urate (Rattus norvegicus)


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Mus musculus)


name: cholesterol + H(+) + NADPH + O2 = 26-hydroxycholesterol + H2O + NADP(+)


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Caenorhabditis elegans)


name: SOAT can transport taurolithocholate-3-sulphate (Xenopus tropicalis)


name: SFKs phosphorylate VAV2,3 (Caenorhabditis elegans)


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Homo sapiens)


name: THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 (Bos taurus)


name: DKK promotes clathrin-dependent internalization of LRP6 (Homo sapiens)


name: Recognition and Binding of Core Promoter Elements by TFIID (Schizosaccharomyces pombe)


name: (4Z,15Z)-bilirubin IXalpha + NADP(+) => biliverdin IXalpha + H(+) + NADPH


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Mus musculus)


name: MDH2 dimer dehydrogenates MAL (Rattus norvegicus)


name: LDL + LDLR => LDL:LDLR complex (Bos taurus)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + tsukubadiene


name: H(+)(out) + L-glutamate(out) + L-glutamine(in) + Na(+)(out) <=> H(+)(in) + L-glutamate(in) + L-glutamine(out) + Na(+)(in)


name: PIAS1 SUMOylates SATB1 with SUMO1 (Mus musculus)


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Canis familiaris)


name: PRMT1 methylates ESRs (Drosophila melanogaster)


name: GLRA:GLRB:Gly transports extracellular Cl- to cytosol (Canis familiaris)


name: (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + malonyl-CoA <=> 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + CO2 + CoA


name: Activation of Rho by LARG and PDZ-RhoGEF (Mus musculus)


name: p-MAPKAPK3 phosphorylates BMI1 (Sus scrofa)


name: Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Homo sapiens)


name: Na+/H+ exchanger transport (at cell membrane) (Schizosaccharomyces pombe)


name: The complex of RUNX2 and WWTR1 (TAZ) binds the BGLAP gene promoter (Homo sapiens)


name: Autophosphorylation of PAK1,2,3 (Rattus norvegicus)


name: GTP-bound RAC contributes to JNK activation (Caenorhabditis elegans)


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O <=> (14S,15S)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: (3S)-6-acetamido-3-aminohexanoate + CoA + H(+) => (3S)-3,6-diaminohexanoate + acetyl-CoA


name: eNOS:NOSIP translocation from caveolae to intracellular compartments (Bos taurus)


name: RHOA binds effectors at the ER membrane (Bos taurus)


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Xenopus tropicalis)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Homo sapiens)


name: very-long-chain 3-oxoacyl-CoA reductase activity


name: a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine => a lipid A disaccharide + H(+) + UDP


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Bos taurus)


name: Opioid receptors bind opioid peptides (Sus scrofa)


name: L-hexahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-9-(methylsulfanyl)nonanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: PSMD14 cleaves K63-linked ubiquitin (Xenopus tropicalis)


name: calcitetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (1S)-1,25-dihydroxy-24-oxocalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Saccharomyces cerevisiae)


name: a short-chain fatty acyl-CoA + H2O = a short-chain fatty acid + CoA + H(+)


name: (S)-2-hydroxyglutarate + NAD(+) => 2-oxoglutarate + H(+) + NADH


name: H2O + streptomycin 6-phosphate = phosphate + streptomycin


name: MeSeO2H is reduced to MeSeOH by TXNRD1 (Homo sapiens)


name: 11-cis-retinol + a fatty acyl-CoA <=> 11-cis-retinyl ester + CoA


name: Crk binds to the active PDGF receptor (Caenorhabditis elegans)


name: CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate <=> acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: GP1b-IX-V binds 14-3-3-zeta (Mus musculus)


name: SMURF1/2 dissociates from ub-PTCH1 (Mus musculus)


name: (6E)-8-hydroxygeraniol + 2 NADP(+) => (6E)-8-oxogeranial + 2 H(+) + 2 NADPH


name: Tenascins C, R, (X, N) bind lecticans (Bos taurus)


name: butan-1-ol + propanoyl-CoA = butyl propanoate + CoA


name: JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Canis familiaris)


name: 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n) => NADP(+) + reduced coenzyme F420-(gamma-L-Glu)(n)


name: K63polyUb-TRAF6 ubiquitinates TAK1 (Sus scrofa)


name: 2-oxoglutarate + DIBOA beta-D-glucoside + O2 <=> CO2 + succinate + TRIBOA beta-D-glucoside


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Canis familiaris)


name: 3-O-(beta-D-xylosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+) => a dolichyl D-xylosyl phosphate + L-seryl-[protein]


name: all-trans-13,14-dihydroretinol + NAD(+) = all-trans-13,14-dihydroretinal + H(+) + NADH


name: a triacylglycerol + an acyl-3-O-(beta-D-galactosyl)-sn-glycerol => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O = a fatty acid + beta-D-glucosyl-(1<->1)-sphing-4-enine


name: (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10-formyltetrahydrofolate + ADP + phosphate


name: CK2 phosphorylates PDCL (Caenorhabditis elegans)


name: VTN binds collagens II, III and V (Rattus norvegicus)


name: an aldose + H(+) + NADPH => an alditol + NADP(+)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Homo sapiens)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Sus scrofa)


name: 5beta-dihydrocorticosterone + NADP(+) => corticosterone + H(+) + NADPH


name: 5-fluorouridine + ATP => 5-fluorouridine 5'-phosphate + ADP + H(+)


name: dimethylallyl diphosphate + 4 isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate


name: Association of Cyclin A:Cdk2 with Cdh1 (Canis familiaris)


name: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H(+) + NADH => 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)


name: UDP-glucose transmembrane transporter activity


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Dictyostelium discoideum)


name: an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O = a guanosine in RNA + H(+) + lactate


name: SLC26A4 transports I- from cytosol to extracellular region (Xenopus tropicalis)


name: a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH


name: guanosine(10) in tRNA + 2 S-adenosyl-L-methionine => 2 H(+) + N(2)-dimethylguanosine(10) in tRNA + 2 S-adenosyl-L-homocysteine


name: Movement of clathrin coated vesicles into early endosome (Danio rerio)


name: Interaction of PECAM-1 and PLC gamma1 (Bos taurus)


name: SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Drosophila melanogaster)


name: ASIC3 channel blockers bind ASIC3 trimer (Canis familiaris)


name: F-actin capping protein is a heterodimer (Plasmodium falciparum)


name: malvidin 3-O-beta-D-glucoside + UDP => malvidin + UDP-alpha-D-glucose


name: Activated NOD1 oligomerizes (Rattus norvegicus)


name: (20S)-ginsenoside F2 + UDP-alpha-D-glucose = (20S)-ginsenoside Rd + H(+) + UDP


name: Fibrillin-1 degradation by MMP14 (Canis familiaris)


name: anisole + O2 + reduced [NADH--hemoprotein reductase] <=> formaldehyde + H(+) + H2O + oxidized [NADH--hemoprotein reductase] + phenol


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Canis familiaris)


name: estrone 3-sulfate(out) + hydrogencarbonate(in) = estrone 3-sulfate(in) + hydrogencarbonate(out)


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Caenorhabditis elegans)


name: ALKBH2 binds alkylated DNA containing 1-etA (Homo sapiens)


name: methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity


name: Activated MET recruits GRB2-1:SOS1 (Homo sapiens)


name: 8-demethyl-8-(methylamino)riboflavin + S-adenosyl-L-methionine = H(+) + roseoflavin + S-adenosyl-L-homocysteine


name: RNF181 binds BCL10 and Ubiquitin:E2 (Rattus norvegicus)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: Transport of MHC I:Nef:AP-1:PACS-1 Complex (Homo sapiens)


name: L-galactonate + NADP(+) => aldehydo-D-galacturonate + H(+) + NADPH


name: H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + n Na(+)(in) => CO2 + N(6)-biotinyl-L-lysyl-[protein] + n Na(+)(out)


name: ATP + H2O + L-isoleucine(out) <=> ADP + H(+) + L-isoleucine(in) + phosphate


name: H2O + L-tryptophanamide => L-tryptophan + NH4(+)


name: SREBP1A,1C,2 binds Importin beta-1 (Drosophila melanogaster)


name: AKT1 E17K mutant phosphorylates NR4A1 (NUR77) (Homo sapiens)


name: prephenate + S-adenosyl-L-methionine => 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Bos taurus)


name: RNF41 ubiquitinates activated ERBB3 (Bos taurus)


name: (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA + NAD(+) <=> 3,22-dioxochol-4-en-24-oyl-CoA + H(+) + NADH


name: Activation of Ca permeable AMPA receptors (Drosophila melanogaster)


name: TGFBR2 phosphorylates TGFBR1 (Sus scrofa)


name: MAP2K2 binds MAPK1 (Dictyostelium discoideum)


name: O2 + reduced [NADPH--hemoprotein reductase] + sophoraflavanone B <=> H(+) + H2O + leachianone G + oxidized [NADPH--hemoprotein reductase]


name: CO2 + L-xylulose 5-phosphate => 3-dehydro-L-gulonate 6-phosphate + H(+)


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Schizosaccharomyces pombe)


name: [eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O


name: (R)-3,4-dihydroxymandelaldehyde + H2O2 + methylamine => (R)-adrenaline + H2O + O2


name: Formation of COPII vesicle (Homo sapiens)


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Saccharomyces cerevisiae)


name: H(+) + oxidized [electron-transfer flavoprotein] + phloretate => (E)-4-coumarate + reduced [electron-transfer flavoprotein]


name: KRAB-ZNF / KAP Interaction (Gallus gallus)


name: O2 + putrescine = 1-pyrroline + H2O2 + NH4(+)


name: 2 2-oxoglutarate + gibberellin A12 + H(+) + 3 O2 <=> 3 CO2 + gibberellin A9 + 2 H2O + 2 succinate


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Drosophila melanogaster)


name: DENND5A,B exchange GTP for GDP on RAB39 (Sus scrofa)


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Canis familiaris)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Caenorhabditis elegans)


name: ABC7, mABC1 and mABC2 mediate heme transport (Canis familiaris)


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Dictyostelium discoideum)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Schizosaccharomyces pombe)


name: CDP-D-glucitol + NADP(+) <=> CDP-6-keto-D-fructose + H(+) + NADPH