name: CDKAL1:4Fe-4S methylthiolates N6-threonylcarbamoyladenosine-37 in tRNA yielding 2-methylthio-N6-threonylcarbamoyladenosine-37 (Homo sapiens)


name: 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + NADP(+)


name: RNA Pol II initiates transcription from damaged DNA template (Dictyostelium discoideum)


name: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+) <=> a (3R)-2'-hydroxyisoflavanone + H(+) + NADPH


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H2O => 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: AH2 + archaeol + 2 S-adenosyl-L-methionine => 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + macrocyclic archaeol


name: 2-oxoglutarate + O2 + taurine <=> aminoacetaldehyde + CO2 + H(+) + succinate + sulfite


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Drosophila melanogaster)


name: asc-C7-CoA + O2 <=> asc-DeltaC7-CoA + H2O2


name: AFG3L2 degrades mitochondrial matrix proteins (Caenorhabditis elegans)


name: DNA polymerase:primase binds G-strand of the telomere (Bos taurus)


name: hydrogencarbonate(out) + iodide(in) <=> hydrogencarbonate(in) + iodide(out)


name: phenylethanolamine + S-adenosyl-L-methionine = H(+) + N-methylphenylethanolamine + S-adenosyl-L-homocysteine


name: The PACAP receptor binds PACAP (Danio rerio)


name: (2R,3R)-dihydroquercetin + H(+) + NADPH + O2 => (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + 2 H2O => 2 a carboxylate + 2 H(+) + sn-glycero-3-phospho-L-serine


name: Recruitment of BCAR1 to PTK2 complex (Canis familiaris)


name: an N(4)-(oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] + H2O <=> an oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-D-GlcNAc + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein]


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Rattus norvegicus)


name: Translesion synthesis across unhooked ICL by POLN (Sus scrofa)


name: dodecanoyl-CoA + H2O + oxaloacetate <=> (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+)


name: NAD(+) + scyllo-inosose = 3-dehydro-scyllo-inosose + H(+) + NADH


name: ALAD condenses 2 dALAs to form PBG (Plasmodium falciparum)


name: a quinone + H(+) + NADH = a quinol + NAD(+)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTPN7 dephosphorylates p-T,Y-MAPKs (Rattus norvegicus)


name: 3-oxoadipate + NADP(+) <=> H(+) + maleylacetate + NADPH


name: Binding of the MCC complex to the APC/C complex (Mus musculus)


name: (2E,6E)-farnesyl diphosphate => (-)-beta-barbatene + diphosphate


name: PANK4 hydrolyzes PPANT to pantetheine (Bos taurus)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => (8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: A1 and A3 receptors bind adenosine (Mus musculus)


name: RNF146 polyubiquitinates PARylated PTEN (Drosophila melanogaster)


name: Dissociation of  transcript with 5'-GMP from GT (Canis familiaris)


name: Start codon recognition (Dictyostelium discoideum)


name: FOLR2 transports FOLA from extracellular region to cytosol (Mus musculus)


name: Melatonin receptors can bind melatonin (Caenorhabditis elegans)


name: L-Glutamate loading of synaptic vesicle (Caenorhabditis elegans)


name: (6S)-5,6,7,8-tetrahydrofolate + vanillate = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 3,4-dihydroxybenzoate


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Rattus norvegicus)


name: ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A <=> ADP + an L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: (9Z)-octadecenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+) => 1-O-(1Z-hexadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Rattus norvegicus)


name: 3,3'-diiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) = 3,3'-diiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: 7,12-dioxo-lithocholate + H(+) + NADPH => 3alpha,7beta-dihydroxy-12-oxo-5beta-cholan-24-oate + NADP(+)


name: DHAP is converted to G3P by GPD1/GPD1L (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: AH2 + trichloroethene = (Z)-1,2-dichloroethene + A + chloride + H(+)


name: 2-methoxy-6-(all-trans-octaprenyl)phenol + H(+) + NADPH + O2 => 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + H2O + NADP(+)


name: 4 ATP = cyclic tetraadenylate + 4 diphosphate


name: Active ALK phosphorylates PLCG1 (Bos taurus)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Canis familiaris)


name: Inactivation of PLC beta (Schizosaccharomyces pombe)


name: H2O + L-serine + NAD(+) = 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Bos taurus)


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Homo sapiens)


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Danio rerio)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Xenopus tropicalis)


name: Pink1 is cleaved on healthy mitochondria (Caenorhabditis elegans)


name: adenosine 3',5'-bisphosphate + H(+) + taurocholate 7-sulfate => 3'-phosphoadenylyl sulfate + taurocholate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine


name: cAMP activates EPAC2 (Saccharomyces cerevisiae)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Canis familiaris)


name: (S)-phenylacetylcarbinol + NAD(+) <=> 1-phenyl-1,2-propanedione + H(+) + NADH


name: DLD dimer dehydrogenates dihydrolipoyl (Mus musculus)


name: 6'-oxoparomamine + H2O2 => O2 + paromamine


name: SAICAR => AICAR + Fumarate (Canis familiaris)


name: Trafficking of nonameric complex in the endocytic pathway (Mus musculus)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O


name: CTP + phosphonoformate <=> CMP-5'-phosphonoformate + diphosphate


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Xenopus tropicalis)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: p-T774-PKN1 phosphorylates PPP1R14A (Canis familiaris)


name: ADP + D-glucosamine = AMP + D-glucosamine 6-phosphate + H(+)


name: PP2A dephosphorylates RAF1 (Caenorhabditis elegans)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Canis familiaris)


name: SCARB1:ligand is endocytosed (Gallus gallus)


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Drosophila melanogaster)


name: ATP + H(+) + IC-asc-C7 = diphosphate + IC-asc-C7-AMP


name: (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + NAD(+) = 2 H(+) + L-pyrrolysine + NADH + NH4(+)


name: Vesicular inhibitory amino acid transport (Gallus gallus)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Sus scrofa)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Mus musculus)


name: ATP + H(+)(in) + H2O => ADP + 2 H(+)(out) + phosphate


name: MSH2:MSH3 binds insertion/deletion loop of 2 bases or more (Schizosaccharomyces pombe)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3  phosphorylates STAT1,STAT3 (Mus musculus)


name: a ganglioside GM1 + H2O => an N-acyl-sphingoid base + beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-D-Glc


name: kallikrein binds SERPING1 (Mus musculus)


name: TLE tetramers bind TCF/LEF at WNT promoters (Gallus gallus)


name: BTNL2 binds activated T cells surface (Bos taurus)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Drosophila melanogaster)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Sus scrofa)


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Schizosaccharomyces pombe)


name: Binding of TFIIIA To type 1 Promoter (Mus musculus)


name: chloride(out) + Na(+)(out) + serotonin(out) => chloride(in) + Na(+)(in) + serotonin(in)


name: (indol-3-yl)acetyl-CoA + AMP + H(+) => (indol-3-yl)acetyl-AMP + CoA


name: USP8 deubiquitinates RNF128 (Homo sapiens)


name: (2Z,6E)-farnesyl diphosphate <=> (-)-gamma-cadinene + diphosphate


name: CHIP (STUB1) mediates ubiquitination of ERBB2 (Rattus norvegicus)


name: H(+) + levopimaradienol + NADPH + O2 = 2 H2O + levopimaradienal + NADP(+)


name: Exchange of oxygen with sulfur in MoCo (Bos taurus)


name: a dicarboxylate(out) + L-erythro-7,8-dihydrobiopterin(in) => a dicarboxylate(in) + L-erythro-7,8-dihydrobiopterin(out)


name: dihydroxyacetone phosphate <=> methylglyoxal + phosphate


name: Loading of acetylcholine in synaptic vesicles (Sus scrofa)


name: Expression of Macrophage migration inhibitory factor (Homo sapiens)


name: p-PKR dimer phosphorylates SPHK1 (Homo sapiens)


name: Phosphorylated TAK1 dissociates from the TLR3 receptor complex (Homo sapiens)


name: sphing-4-enine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoyl-sphing-4-enine


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Canis familiaris)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Mus musculus)


name: [(1->2)-beta-D-glucosyl](n) + H2O <=> [(1->2)-beta-D-glucosyl](n-2) + sophorose


name: AKR1C1 hydrogenates PREDN,PREDL (Schizosaccharomyces pombe)


name: H2O + limonene 1,2-epoxide => limonene-1,2-diol


name: ECHS1 hydrates methacrylyl-CoA (Sus scrofa)


name: PA is converted to CDP-DAG by CDS2 (Dictyostelium discoideum)


name: hydrogen cyanide + thiosulfate <=> 2 H(+) + sulfite + thiocyanate


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)


name: ME1 tetramer decarboxylates OA to PYR (Sus scrofa)


name: polymeric immunoglobulin receptor activity


name: (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + CO2 + CoA


name: 2-oxoglutarate + L-methionine = 4-methylsulfanyl-2-oxobutanoate + L-glutamate


name: (2E)-eicosenoyl-CoA + FADH2 => eicosanoyl-CoA + FAD + H(+)


name: kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin (Xenopus tropicalis)


name: Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Xenopus tropicalis)


name: chrodrimanin A + H2O + NADP(+) => chrodrimanin T + H(+) + NADPH + O2


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 1,3-di-(9Z-octadecenoyl)-glycerol + H(+)


name: Tenascins C, R, (X, N) bind lecticans (Xenopus tropicalis)


name: 15-cis-phytoene + 2 plastoquinone-9 = 9,9',15-tri-cis-zeta-carotene + 2 plastoquinol-9


name: adenosine(57)/adenosine(58) in tRNA + 2 S-adenosyl-L-methionine => 2 H(+) + N(1)-methyladenosine(57)/N(1)-methyladenosine(58) in tRNA + 2 S-adenosyl-L-homocysteine


name: Interaction of PECAM-1 and SHIP (Sus scrofa)


name: H2O + N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] => 2-hydroxy-2-methylpropanoate + L-lysyl-[protein]


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Xenopus tropicalis)


name: STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Xenopus tropicalis)


name: cytidine(38) in tRNA + S-adenosyl-L-methionine => 5-methylcytidine(38) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: RHOQ GAPs stimulate RHOQ GTPase activity (Homo sapiens)


name: (9Z)-tetradecenoate(out) + ATP(in) + CoA(in) + H(+)(out) <=> (9Z)-tetradecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP => (indol-3-yl)acetate + UDP-alpha-D-glucose


name: ACAD11 dehydrogenates BH-CoA (Mus musculus)


name: H(+)(out) + K(+)(in) + L-glutamate(out) + 3 Na(+)(out) = H(+)(in) + K(+)(out) + L-glutamate(in) + 3 Na(+)(in)


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Canis familiaris)


name: a ganglioside Ac-O-9-GD3 + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside Ac-O-9-GD2 + H(+) + UDP


name: a 1-acyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-acyl-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O


name: 3 Na(+)(out) + sulfate(out) => 3 Na(+)(in) + sulfate(in)


name: 2 Fe(III)-[cytochrome c] + S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein]


name: H2O + N(2)-(1-hydroxy-2-oxoethyl)-GMP <=> glycolate + GMP + H(+)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Xenopus tropicalis)


name: L-arginine(out) + L-glutamine(in) + Na(+)(in) => L-arginine(in) + L-glutamine(out) + Na(+)(out)


name: NTPDase6 hydrolyzes nucleoside diphosphates (Danio rerio)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane (Sus scrofa)


name: an isogloboside iGb3Cer (d18:1(4E)) + H(+) + UDP => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Sus scrofa)


name: 13-cis-retinal + H2O + NAD(+) => 13-cis-retinoate + 2 H(+) + NADH


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + (E)-caffeoyl-CoA = (R)-rosmarinate + CoA


name: 3beta-hydroxy-5alpha-androstan-17-one + UDP-alpha-D-glucose => epiandrosterone 3-beta-D-glucoside + H(+) + UDP


name: (6E)-8-hydroxylinalool + O2 + reduced [NADPH--hemoprotein reductase] => (6E)-8-oxolinalool + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PIAS4 SUMOylates IKBKG with SUMO1 (Mus musculus)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Canis familiaris)


name: Defective RPIA does not isomerize RU5P to R5P (Homo sapiens)


name: dihydroxyacetone phosphate + L-aspartate 4-semialdehyde => 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate


name: 9-hydroxy-octadecanoate + a triacylglycerol = 9-(acyloxy)-octadecanoate + a 2,3-diacyl-sn-glycerol


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: 4-amino-5-hydroxy-3-all-trans-hexaprenylbenzoate + 5 H(+) + O2 + 4 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + NH4(+) + 4 oxidized [2Fe-2S]-[ferredoxin]


name: CLCN7:OSTM1 exchanges Cl- for H+ (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate <=> (+)-aristolochene + diphosphate


name: a 2-demethylmenaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine = 5'-deoxyadenosine + a 2-demethyl-8-methylmenaquinone + 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L-homocysteine


name: FNTB inhibitors bind FNTA:FNTB (Xenopus tropicalis)


name: p-S295-PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)


name: 3-hydroxy-1H-quinolin-4-one + O2 <=> CO + H(+) + N-formylanthranilate


name: thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] (Homo sapiens)


name: Laminin-322 degradation by MMP14 (Homo sapiens)


name: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoate = acetate + vanillin


name: Elastin cross-linking by lysyl oxidase (Rattus norvegicus)


name: Phosphorylation and release of IRF3 (Gallus gallus)


name: Collagen type III degradation by MMP1,8,9,13 (Rattus norvegicus)


name: 1-octadecanoylglycerol + H2O <=> glycerol + H(+) + octadecanoate


name: (3Z)-phycoerythrobilin + 2 oxidized 2[4Fe-4S]-[ferredoxin] <=> biliverdin IXalpha + 4 H(+) + 2 reduced 2[4Fe-4S]-[ferredoxin]


name: L-valine(in) + Na(+)(in) <=> L-valine(out) + Na(+)(out)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Drosophila melanogaster)


name: p-T,Y MAPK dimers translocate to nucleus (Saccharomyces cerevisiae)


name: S-benzyl-L-cysteine => 2-aminoprop-2-enoate + benzylthiol


name: (-)-alpha-cuprenene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Xenopus tropicalis)


name: a 2-oxocarboxylate + L-ornithine => an L-alpha-amino acid + L-glutamate 5-semialdehyde


name: Inhibition of MDA5-IPS1 signaling by Atg5-Atg12 conjugate (Gallus gallus)


name: UGTs transfer GlcA from UDP-GlcA to O-centre substrates (Mus musculus)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Drosophila melanogaster)


name: SUMOylation of NFKBIA with SUMO1 (Xenopus tropicalis)


name: GLB1 hydrolyses a glycosaminoglycan (Dictyostelium discoideum)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(28-hydroxyoctacosanoyl)-sphing-4-enine <=> a diacylglycerol + N-(28-(9Z,12Z-octadecadienoyloxy)-octacosanoyl)-sphing-4-enine


name: 6-trans-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy-6-trans-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + O2 + proclavaminate <=> CO2 + dihydroclavaminate + H2O + succinate


name: Interaction of NUMB with L1 (Mus musculus)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Canis familiaris)


name: 3 Na(+)(out) + thiosulfate(out) => 3 Na(+)(in) + thiosulfate(in)


name: O2 + reduced [NADPH--hemoprotein reductase] + vinorine <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + vomilenine


name: SEC4C,D bind GOSR2 and STX5 (Rattus norvegicus)


name: 4-hydroxyphenylacetyl-CoA + H2O <=> 4-hydroxyphenylacetate + CoA + H(+)


name: odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Bos taurus)


name: H(+) + ketocytochalasin + NADPH + O2 <=> H2O + iso-precytochalasin + NADP(+)


name: Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Mus musculus)


name: all-trans-zeaxanthin + O2 => (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal


name: butan-1-ol + NADP(+) => butanal + H(+) + NADPH


name: (9Z)-tetradecenoyl-CoA + (R)-carnitine = CoA + O-(9Z)-tetradecenoyl-(R)-carnitine


name: Hikeshi binds HSP70s:ATP (Canis familiaris)


name: 2 3-(4-hydroxyphenyl)pyruvate + O2 = 2 4-hydroxyphenylacetate + 2 CO2


name: (9Z,12Z,15Z)-octadecatrienoate + O2 <=> 13-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: dimethylallyl diphosphate + leachianone G => diphosphate + sophoraflavanone G


name: 2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2'-hydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2,3-dihydroxybenzoate + ATP + H(+) = 2,3-dihydroxybenzoyl-5'-AMP + diphosphate


name: 3-oxooctadecanoyl-CoA + CO2 + CoA => H(+) + hexadecanoyl-CoA + malonyl-CoA


name: PKC alpha interacts with and phosphorylates KIT (Mus musculus)


name: AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Mus musculus)


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Canis familiaris)


name: GAR + 10-Formyl-THF => FGAR + THF (Rattus norvegicus)


name: (2E,4E,6E)-octa-2,4,6-trienyl-[ACP] + AH2 + 3 H(+) + 4 malonyl-CoA => 2,4-dihydroxy-6-[(3E,5E,7E)-2-oxonona-3,5,7-trienyl]benzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP]


name: fumarate(in) + L-aspartate(out) = fumarate(out) + L-aspartate(in)


name: CYP27A1 27-hydroxylates CHOL (Rattus norvegicus)


name: Ac-PTGS2 dimer oxidises EPA to 18(R)-HpEPE or 18(S)-HpEPE (Sus scrofa)


name: glycine betaine + H(+) + NADH + O2 => glyoxylate + H2O + NAD(+) + trimethylamine


name: 1-heptadecanoyl-sn-glycero-3-phosphate + dodecanoyl-CoA <=> 1-heptadecanoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: D-glucarate + 3 H(+) + NADH => D-glucurono-3,6-lactone + 2 H2O + NAD(+)


name: ALD3A1 oxidises 4HPCP to CXPA (Drosophila melanogaster)


name: RHOBTB3 binds ATP (Caenorhabditis elegans)


name: OSM,LIF,CTF1 receptor complex binds gp130 (Rattus norvegicus)


name: Antizyme OAZ binds to Ornithine decarboxylase (Rattus norvegicus)


name: Type B histone acetlytransferase complex acetylates histone H4 (Homo sapiens)


name: Activation of Ca permeable AMPA receptors (Gallus gallus)


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Sus scrofa)


name: PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Bos taurus)


name: 2'-N-acetylparomamine + H2O => acetate + paromamine


name: an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = an anthocyanidin 3,5-di-O-beta-D-glucoside + 2 H(+) + UDP


name: (S)-pinocembrin + O2 + reduced [NADPH--hemoprotein reductase] <=> (2S)-2-hydroxypinocembrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Mus musculus)


name: ARBB recruits GPCRs into clathrin-coated pits (Sus scrofa)


name: CARKD dehydrates S-NAD(P)HX to NADPH (Drosophila melanogaster)


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Rattus norvegicus)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Danio rerio)


name: IDH3 complex decarboxylates isocitrate (Saccharomyces cerevisiae)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Dictyostelium discoideum)


name: a (2E)-2-fatty-enoyl-AMP + holo-[ACP] => a (2E)-enoyl-[ACP] + AMP + H(+)


name: ILF3 binds CDH11 gene promoter (Homo sapiens)


name: RUNX1 binds SIN3A,(SIN3B) co-repressor (Bos taurus)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Sus scrofa)


name: 4',7-dihydroxy-3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine


name: D-cycloserine(out) + H(+)(out) => D-cycloserine(in) + H(+)(in)


name: an N-(acyl)-sphingosylphosphocholine(in) <=> an N-(acyl)-sphingosylphosphocholine(out)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2 = 2-dehydro-D-glucose + H2O2 + L-phenylalanine


name: an L-alpha-amino acid <=> a D-alpha-amino acid


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Sus scrofa)


name: InlB:MET dimer trans-autophophorylates (Homo sapiens)


name: dimethyl disulfide + H(+) + NADH => 2 methanethiol + NAD(+)


name: (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase] <=> 8-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: EP300 acetylates histone H2A, H2B, H3, H4 (Xenopus tropicalis)


name: 3''-dehydropuerarin => 1,5-anhydro-D-erythro-hex-1-en-3-ulose + daidzein


name: Pancreatic proteases degrade TCN1:RCbl (Bos taurus)


name: MLCL is acylated to CL by LCLAT1 (ER) (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: TRAF6 is auto-ubiquitinated (Rattus norvegicus)


name: AMP(out) + FMN(in) <=> AMP(in) + FMN(out)


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Sus scrofa)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + CDP-ethanolamine <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: B3GAT dimers transfer GlcA to tetrasaccharide linker (Mus musculus)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Xenopus tropicalis)


name: p62 recruits an atypical PKC (Bos taurus)


name: H(+) + NADPH + NH4(+) + oxaloacetate => H2O + L-aspartate + NADP(+)


name: 5beta-androstane-3,17-dione + NADP(+) => androst-4-ene-3,17-dione + H(+) + NADPH


name: Mycothiol scavenges nitrosyl (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate


name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Gallus gallus)


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Homo sapiens)


name: Pellino ubiquitinates IRAK1 (Danio rerio)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E)-docosapentaenoate


name: Activation of Rap1 by cytosolic GEFs (Mus musculus)


name: Activated FGFR2 phosphorylates FRS3 (Danio rerio)


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Xenopus tropicalis)


name: ATP + hexadecanoate + holo-[(hydroxy)phthioceranic acid synthase] <=> AMP + diphosphate + hexadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: Initial activation of proMMP7 by trypsin (Canis familiaris)


name: (R)-carnitine + tetradecanoyl-CoA => CoA + O-tetradecanoyl-(R)-carnitine


name: USP30 deubiquitinates Ub-MOM proteins (Homo sapiens)


name: (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) <=> 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + NADH


name: Activation of Potassium transport channels (Caenorhabditis elegans)


name: structural constituent of postsynaptic specialization


name: 2 chloride(in) + H(+)(out) <=> 2 chloride(out) + H(+)(in)


name: cellobiose dehydrogenase (acceptor) activity


name: Phosphorylation of PLC-gamma1 (Canis familiaris)


name: a ganglioside Ac-O-8-GT3 = a ganglioside Ac-O-9-GT3


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Dictyostelium discoideum)


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Xenopus tropicalis)


name: 6-dehydro-D-glucose + H(+) + NADPH => D-glucose + NADP(+)


name: H(+) + 2 H2O2 + hexadecanoate = CO2 + 3 H2O + pentadecanal


name: Guanine + H2O => Xanthine + NH4+ (Homo sapiens)


name: TNPO1 binds KIF17 dimer (Rattus norvegicus)


name: D-galactose + sphing-4-enine => beta-D-galactosyl-(1<->1)-sphing-4-enine + H2O


name: 2-acyl LPG is acylated to PG by LPGAT (Dictyostelium discoideum)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CO2 + CoA


name: glycerophosphodiester transmembrane transporter activity


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out)


name: chloride + H(+) + hydroxyatrazine => atrazine + H2O


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Canis familiaris)


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Xenopus tropicalis)


name: 3 AH2 + ATP + H2O + Ni-sirohydrochlorin a,c-diamide <=> 15,17(3)-seco-F430-17(3)-acid + 3 A + ADP + phosphate


name: Phosphorylated STAT3 Dimer Translocates to the Nucleus (Homo sapiens)


name: RIP2 is K63 polyubiquitinated (Mus musculus)


name: RBBP7 binds histone H3 (Caenorhabditis elegans)


name: (2S)-2-acetamido-4-aminobutanoate + H2O <=> acetate + L-2,4-diaminobutanoate


name: (1S,2S,4R)-endo-fenchol + NAD(+) => (1S,4R)-fenchone + H(+) + NADH


name: Inactive BRAF mutants bind mutant RAS:GTP (Homo sapiens)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Plasmodium falciparum)


name: a flavonol 3-O-beta-D-glucoside + malonyl-CoA <=> a flavonol 3-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Release of activated MAD2 from kinetochores (Rattus norvegicus)


name: Formation of the 43S pre-initiation complex (Plasmodium falciparum)


name: Ubiquitination of stimulated EGFR (CBL) (Caenorhabditis elegans)


name: SEC4C,D bind GOSR2 and STX5 (Gallus gallus)


name: Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA (Xenopus tropicalis)


name: 9alpha-copalyl diphosphate => diphosphate + isopimara-8(14),15-diene


name: adenosine 3',5'-bisphosphate + bisphenyl A sulfate + H(+) => 3'-phosphoadenylyl sulfate + bisphenol A


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Homo sapiens)


name: Trafficking of GluR1-containing  AMPA receptors (Mus musculus)


name: 5beta-pregnan-3,20-dione + H(+) + NADPH => 3alpha-hydroxy-5beta-pregnan-20-one + NADP(+)


name: LIPA hydrolyses sterol esters to sterols and fatty acids (Mus musculus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine => 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol => a 1-acyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol


name: geranylgeranyl diphosphate = diphosphate + fusicocca-2,10(14)-diene


name: glutathione(in) + leukotriene C4(out) <=> glutathione(out) + leukotriene C4(in)


name: p-S MAPK6,4 phosphorylate MAPKAPK5 (Rattus norvegicus)


name: SCARF1 (SREC-I) binds ligands (Homo sapiens)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O = (9Z,12Z)-octadecadienoate + 2,3-di-(9Z,12Z)-octadecadienoyl-sn-glycerol + H(+)


name: 2 glutathione + tert-butyl hydroperoxide => glutathione disulfide + H2O + tert-butanol


name: CoA + O-octanoyl-(R)-carnitine => (R)-carnitine + octanoyl-CoA


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Mus musculus)


name: PAOX:FAD oxidises NASPN to SPM (Canis familiaris)


name: ALDH8A1 oxidises 9cRAL to 9cRA (Danio rerio)


name: GAR + 10-Formyl-THF => FGAR + THF (Caenorhabditis elegans)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + A + H2O = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + AH2


name: acrylate + dimethyl sulfide + H(+) => S,S-dimethyl-beta-propiothetin


name: 3-demethylubiquinol-8 + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + ubiquinol-8


name: Expression of STAT3-upregulated nuclear proteins (Homo sapiens)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Canis familiaris)


name: coenzyme M + methyl-Co(III)-[methylamine-specific corrinoid protein] = Co(I)-[methylamine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: A + beta-dihydromenaquinone-9 => AH2 + menaquinone-9


name: 2-(acylamino)ethyl fatty acid + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylethanolamine


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Mus musculus)


name: STAB2 (FEEL-2) binds ligands (Gallus gallus)


name: ATP12A:ATP4B exchanges K+ for H+ (Bos taurus)


name: p-PKR dimer phosphorylates CDK1 (Gallus gallus)


name: genistein + H(+) + H2O => 2-hydroxy-2,3-dihydrogenistein


name: c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  (Bos taurus)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base = a diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base


name: NADP(+) + octadecanoyl-[ACP] => (2E)-octadecenoyl-[ACP] + H(+) + NADPH


name: Interaction of Nectins with Afadin (Gallus gallus)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Xenopus tropicalis)


name: NEIL1 recognizes and binds thymine glycol (Homo sapiens)


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Drosophila melanogaster)


name: ZnT8 transports zinc into the Golgi apparatus (Drosophila melanogaster)


name: Extrusion of 5'-end of 30 nt long HIV-1 transcript through the pore in Pol II complex (Homo sapiens)


name: 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O <=> 2 AMP + H(+)


name: 2-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: 3'-phosphoadenylyl sulfate + an aliphatic (Z)-desulfo-glucosinolate => a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + adenosine 3',5'-bisphosphate + H(+)


name: a ribonucleoside 5'-triphosphate + phytyl phosphate <=> a ribonucleoside 5'-diphosphate + phytyl diphosphate


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Danio rerio)


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Gallus gallus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA


name: TRAF6 is K63 poly-ubiquitinated (Mus musculus)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Saccharomyces cerevisiae)


name: a 3-oxo-5alpha-steroid + NADP(+) => a 3-oxo-Delta(4)-steroid + H(+) + NADPH


name: beta-alanyl-L-lysine + H2O = beta-alanine + L-lysine


name: ATP + holo-[(hydroxy)phthioceranic acid synthase] + octadecanoate <=> AMP + diphosphate + octadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: Collagen type II binds integrin alpha2beta1, alpha1beta1, alpha11beta1 (Homo sapiens)


name: (R)-lanthionine ketimine + 2 H(+) + NADPH => (3R,5R)-1,4-thiomorpholine-3,5-dicarboxylate + NADP(+)


name: (E)-feruloyl-CoA + L-quinate <=> 4-O-feruloyl-D-quinate + CoA


name: N,N',N''-triacetylchitotriose + O2 <=> H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone


name: USP37:RUVLB1:PSMC5 deubiquitinates CCNA1,CCNA2 (Caenorhabditis elegans)


name: Formation of ORC(1-6) complex (Schizosaccharomyces pombe)


name: ethanol + 2 Fe(III)-[cytochrome c] = acetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: CDK and DDK associate with the Mcm10:pre-replicative complex (Rattus norvegicus)


name: (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + O2 + reduced [NADPH--hemoprotein reductase]


name: cellulose synthase (GDP-forming) activity


name: ADRA1A,B,D bind ADR,NAd (Xenopus tropicalis)


name: 2 ATP + H2O + hydrogencarbonate + L-glutamine => 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate


name: 2-cis-(+)-abscisate + UDP-alpha-D-glucose <=> beta-D-glucopyranosyl cis-(+)-abscisate + UDP


name: a 3'-end 2'-phospho-ribonucleotide-RNA + H(+) => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O


name: ATP + beta-alanine + histamine => AMP + carcinine + diphosphate + H(+)


name: Dephosphorylation of p107 (RBL1) by PP2A (Canis familiaris)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + lathosterol + O2 = 7-dehydrocholesterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Homo sapiens)


name: 2-oxoglutarate(in) + 3 Na(+)(in) => 2-oxoglutarate(out) + 3 Na(+)(out)


name: H2O + methylenediurea = N-(carboxyaminomethyl)urea + NH4(+)


name: a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase] = a 17alpha-hydroxy-C21-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Rattus norvegicus)


name: CoA + IC-asc-C9-AMP => AMP + H(+) + IC-asc-C9-CoA


name: IKK epsilon is recruited to the Viral dsRNA:TLR3:TICAM1 complex  (Gallus gallus)


name: growth hormone-releasing hormone receptor binding


name: TP53 family members bind PPP1R13B or TP53BP2 (Homo sapiens)


name: 7alpha-hydroxycholesterol + NAD(+) = 7alpha-hydroxycholest-4-en-3-one + H(+) + NADH


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) = 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: NEIL3 cleaves 5-guanidinohydantoin (Bos taurus)


name: 3,4-dihydroxyphenylacetate + chloride + NAD(+) => 4-chlorophenylacetate + NADH + O2


name: PRC2 recruits DNA methyltransferases (Mus musculus)


name: Histone acetyltransferases are recruited to the TFF1 gene (Schizosaccharomyces pombe)


name: XDH oxidizes hypoxanthine to form xanthine (Dictyostelium discoideum)


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Dictyostelium discoideum)


name: phospholipid-hydroperoxide glutathione peroxidase activity


name: Hh-Np traffics to the plasma membrane (Bos taurus)


name: PPTN11 dephosphorylates SPRY2 (Xenopus tropicalis)


name: HMG CoA => acetoacetic acid + acetyl CoA (Bos taurus)


name: 3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O2 => 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD(+)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Gallus gallus)


name: 2 H(+) + pterostilbene + 2 S-adenosyl-L-homocysteine => 2 S-adenosyl-L-methionine + trans-resveratrol


name: chloride(out) + L-phenylalanine(out) + 2 Na(+)(out) = chloride(in) + L-phenylalanine(in) + 2 Na(+)(in)


name: G13 activation by TP receptor (Homo sapiens)


name: Activation of Ca impermeable AMPA receptors (Sus scrofa)


name: D-xylobiose + O2 => D-xylobiono-1,5-lactone + H2O2


name: ALAS condenses SUCC-CoA and Gly to form dALA (Danio rerio)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Gallus gallus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Danio rerio)


name: 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + H(+) + NADH => (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + NAD(+)


name: CoA + glutathione + NADP(+) => CoA-glutathione + H(+) + NADPH


name: bromide(in) + chloride(out) = bromide(out) + chloride(in)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Bos taurus)


name: dimethylallyl phosphate + FMNH2 => phosphate + prenyl-FMNH2


name: ATP + CoA + pentanoate => AMP + diphosphate + pentanoyl-CoA


name: [dermatan sulfate]-L-iduronyl 2-Osulfotransferase activity


name: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively (Homo sapiens)


name: SARS-CoV-2 3CLpro dimer cleaves TAB1 (Homo sapiens)


name: USP12, USP26 deubiquitinate AR (Danio rerio)


name: SEPT4 binds XIAP (Schizosaccharomyces pombe)


name: NGEF exchanges GTP for GDP on RHOA (Xenopus tropicalis)


name: a menaquinol(in) + dimethyl sulfoxide(out) => a menaquinone(in) + dimethyl sulfide(out) + H2O(out)


name: WDR5 binds Me2sR3-replicative histone H3 (Schizosaccharomyces pombe)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Drosophila melanogaster)


name: D-glucosamine + sulfate => H2O + N-sulfo-D-glucosamine


name: H(+) + hexadecanoate + NADPH + O2 => 14-hydroxyhexadecanoate + H2O + NADP(+)


name: bacterial-type RNA polymerase holo enzyme binding


name: CHEK1 is recruited to resected DNA DSBs (Canis familiaris)


name: 1,2-dichloroethane + H2O <=> 2-chloroethanol + chloride + H(+)


name: Calcineurin binds NFATC1,2,3 (Drosophila melanogaster)


name: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine <=> 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine


name: ATP + hydrogencarbonate + NH4(+) <=> ADP + carbamoyl phosphate + H(+) + H2O


name: 6-hydroxyhexanoate + H(+) => H2O + hexano-6-lactone


name: IDS hydrolyses Heparan sulfate chain(5) (Drosophila melanogaster)


name: L-tryptophan + pyruvate = indole-3-pyruvate + L-alanine


name: Thrombin binding to GP1b:IX:V (Mus musculus)


name: ajmalicine + O2 + reduced [NADPH--hemoprotein reductase] <=> dihydroserpentine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Bos taurus)


name: [protein-PII]-uridylyl-L-tyrosine + H2O <=> [protein-PII]-L-tyrosine + H(+) + UMP


name: NNMT transfers CH3 from AdoMet to PY (Sus scrofa)


name: CYP19A1 hydroxylates TEST to EST17b (Danio rerio)


name: ALDH3B2 oxidises HXAL to PALM (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate + 3 isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + 3 diphosphate


name: Active IRS recruits PI3K to the plasma membrane and activates it (Mus musculus)


name: p-S225-SPHK1 localizes to cytosol (Homo sapiens)


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Rattus norvegicus)


name: RBP3 transports 11cRAL to rod photoreceptor outer segment (Xenopus tropicalis)


name: acetate + ajmaline + H(+) => 17-O-acetylajmaline + H2O


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Bos taurus)


name: beta-D-mannopyranosyl-(1->2)-D-mannopyranose + phosphate <=> alpha-D-mannose 1-phosphate + D-mannose


name: STAT binds to the mutant PDGFRA receptor (Homo sapiens)


name: VWF multimer binds to collagen type I (Mus musculus)


name: HNF1B-dependent synthesis of HNF6 protein (Homo sapiens)


name: baicalin + H2O => baicalein + D-glucuronate + H(+)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1,2-dihexanoylglycerol => 1,2-dihexanoyl-3-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + CoA


name: ATP + L-histidine + tRNA(His) => AMP + diphosphate + H(+) + L-histidyl-tRNA(His)


name: N-octanoylsphing-4-enine + phosphate => H2O + N-(octanoyl)-sphing-4-enine-1-phosphate


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Sus scrofa)


name: p-TARBP2 binds PKR (Drosophila melanogaster)


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Dictyostelium discoideum)


name: "With incorporation of two atoms of oxygen"


name: chloride(out) + formate(in) => chloride(in) + formate(out)


name: (2S)-3-(4-hydroxyphenyl)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O => 2-dehydro-D-glucose + L-tyrosine


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate => 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + 2-oxoglutarate + H(+) + H2O


name: 2,4,6-trichlorophenol + FADH2 + O2 = 2-chloro-6-hydroxy-1,4-benzoquinone + 2 chloride + FAD + 3 H(+)


name: SETD6 methylates RELA in the NFkB complex (Homo sapiens)


name: Acireductone is created (Canis familiaris)


name: a tRNA with a 3' CCA end + ATP + 2 CTP => a tRNA with a 3' CCACCA end + 3 diphosphate


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Bos taurus)


name: ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) (Caenorhabditis elegans)


name: 3'-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] => 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) (Xenopus tropicalis)


name: C3a receptor binds anaphylatoxin C3a (Mus musculus)


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Canis familiaris)


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: Proton-coupled histidine and di-peptide cotransport (Gallus gallus)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Canis familiaris)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Rattus norvegicus)


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Caenorhabditis elegans)


name: 1,4-dihydroxy-2-naphthoate + all-trans-nonaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-9 + CO2 + diphosphate


name: a (2E,4E)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)


name: Activation of EPACs by cAMP (Schizosaccharomyces pombe)


name: ATM phosphorylates TTC5 (Rattus norvegicus)


name: BECN1 complex, p-AMBRA1 dissociate from DYNLL1,DYNLL2 (Sus scrofa)


name: DAG is metabolized by DAGL to 2-AG (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate = (E)-2-epi-beta-caryophyllene + diphosphate


name: Dimerization of KIT upon SCF binding (Mus musculus)


name: Activated TrkA receptor internalizes to endosomes (Bos taurus)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)


name: cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Rattus norvegicus)


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-(2S,3R,9R)-pristinol + diphosphate


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Rattus norvegicus)


name: ERBB4 ubiquitination by WWP1/ITCH (Rattus norvegicus)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + propanoate => 1-O-hexadecyl-2-propanoyl-sn-glycero-3-phosphocholine + H2O


name: L-arginyl-[dinitrogen reductase] + NAD(+) = H(+) + N(omega)-alpha-(ADP-D-ribosyl)-L-arginyl-[dinitrogen reductase] + nicotinamide


name: FOXG1 binds FOXO:SMAD complexes (Gallus gallus)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ATP + H2O + selenate(out) => ADP + H(+) + phosphate + selenate(in)


name: ATP + beta-alanine + L-lysine = ADP + beta-alanyl-L-lysine + H(+) + phosphate


name: Rv3364c binds cathepsin G (Homo sapiens)


name: GPI dimer isomerizes Fru(6)P to G6P (Plasmodium falciparum)


name: ERBB4 forms heterodimers with EGFR (Xenopus tropicalis)


name: GLB1 hydrolyses linker chain(2) (Dictyostelium discoideum)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Homo sapiens)


name: H2O + methymycin + 2 oxidized [2Fe-2S]-[ferredoxin] => 10-deoxymethymycin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: a primary linear alkyl sulfate ester + H2O => a primary alcohol + H(+) + sulfate


name: a fatty acyl-[ACP] + L-lysyl-[protein] <=> H(+) + holo-[ACP] + N(6)-(fatty acyl)-L-lysyl-[protein]


name: PGH2 is reduced to PGF2a by AKR1C3 (Rattus norvegicus)


name: Activated FGFR4 phosphorylates PLCG1 (Danio rerio)


name: an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol + H2O => 6-(alpha-D-glucosaminyl)-1D-myo-inositol + a 1,2-diacyl-sn-glycero-3-phosphate + H(+)


name: methyl jasmonate methylesterase activity


name: ABCA12 transports lipids from cytosol to extracellular region (Sus scrofa)


name: GP1b signaling involves c-Src (Rattus norvegicus)


name: L-aspartate + menaquinone-8 <=> iminosuccinate + menaquinol-8


name: 2-oxoglutarate + a (2S)-flavan-4-one + O2 => a (2R,3R)-dihydroflavonol + CO2 + succinate


name: Type II receptor phosphorylates type I receptor (Drosophila melanogaster)


name: Ca impermeable AMPA receptor ligand binding (Homo sapiens)


name: 2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Rattus norvegicus)


name: (9Z)-octadecenoate(out) + ATP(in) + CoA(in) + H(+)(out) => (9Z)-octadecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: (+)-3'-hydroxylarreatricin + A + H2O => (+)-larreatricin + AH2 + O2


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Caenorhabditis elegans)


name: (5E)-tetradecenoyl-CoA + (R)-carnitine <=> (5E)-tetradecenoyl-(R)-carnitine + CoA


name: Recruitment of  RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Schizosaccharomyces pombe)


name: PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 (Mus musculus)


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+) <=> biphenyl-2,3-diol + H(+) + NADH


name: TGFBR2 recruits TGFBR1 (Rattus norvegicus)


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Drosophila melanogaster)


name: PDPK1 phosphorylates AKT2 (Rattus norvegicus)


name: Caspase-mediated cleavage of Lamin B1 (Gallus gallus)


name: TYRP1 oxidises DHICA to IQCA (Mus musculus)


name: bisanhydrobacterioruberin + H2O => monoanhydrobacterioruberin


name: AH2 + N-acetyl-S-hydroxy-L-cysteine = A + H2O + N-acetyl-L-cysteine


name: USP13 and OTUD3 deubiquitinate PTEN (Dictyostelium discoideum)


name: CDK1 phosphorylates RUNX2 (Caenorhabditis elegans)


name: GP1b signaling involves c-Src (Danio rerio)


name: 18-hydroxy-(9S,10R)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (9S,10R)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: a substituted beta-amino acid => a beta-lactam + H2O


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Schizosaccharomyces pombe)


name: Processing of SCF isoform 1 (Homo sapiens)


name: Formation of CSL NCOR corepressor complex (Mus musculus)


name: IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => (3R,6E)-nerolidol + diphosphate


name: cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine <=> 5-methylcytidine(72) in tRNA(Thr) + H(+) + S-adenosyl-L-homocysteine


name: RAC3 translocates to the endoplasmic reticulum membrane (Drosophila melanogaster)


name: 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate => 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Homo sapiens)


name: alpha-D-glucose 6-phosphate + NADP+ => D-glucono-1,5-lactone 6-phosphate + NADPH + H+ (Rattus norvegicus)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacylglycerol = 1-O-alkyl-sn-glycero-3-phosphocholine + a triacylglycerol


name: ATP + ergothioneine(out) + H2O = ADP + ergothioneine(in) + H(+) + phosphate


name: SLC9B1/C2 exchange Na+ for H+ (Mus musculus)


name: D-glucose + NAD(+) <=> D-glucono-1,5-lactone + H(+) + NADH


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate => 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: apoTF binds 2Fe3+ to form holoTF (Drosophila melanogaster)


name: DHRS7B reduces GO3P to HXDG3P (Sus scrofa)


name: (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA <=> (2E,11Z,14Z)-eicosatrienoyl-CoA + H2O


name: adenylyl-molybdopterin + H(+) + tungstate = AMP + H2O + W-molybdopterin cofactor


name: CYP2E1 monooxygenates APAP to NAPQI (Danio rerio)


name: urocanate + H2O => 4-imidazolone-5-propionate (Xenopus tropicalis)


name: adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: Transfer of NEDD8 to AcM-UBE2F (Gallus gallus)


name: ATP + CoA + octanedioate => AMP + diphosphate + octanedioyl-CoA


name: FDPS dimer transfers IPPP to GPP (Schizosaccharomyces pombe)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 19-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation (Homo sapiens)


name: n H(+)(out) + pyridoxine(out) <=> n H(+)(in) + pyridoxine(in)


name: a ganglioside GD1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1b (d18:1(4E)) + CMP + H(+)


name: (2R)-S-methyl-1-thioglycerate + phosphate => (2R)-S-methyl-3-phospho-1-thioglycerate + H2O


name: mutildienyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: 3-dehydroteasterone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => 3-dehydro-6-deoxoteasterone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: MLCL is acylated to CL by LCLAT1 (ER) (Homo sapiens)


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Rattus norvegicus)


name: p-T,Y MAPKs dimerize (Plasmodium falciparum)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Canis familiaris)


name: RDH10,11 oxidise 11cROL to 11cRAL (Danio rerio)


name: Folded full-length TLR7/8/9 dissociates from the GP96:CNPY3 complex  (Rattus norvegicus)


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Caenorhabditis elegans)


name: Interaction of integrin alphaIIbbeta3 with Fibronectin (Gallus gallus)


name: 2-deoxy-alpha-D-ribose 1-phosphate + adenine => 2'-deoxyadenosine + phosphate


name: (8,11R,12S)-trihydroxy-(5Z,9E,14Z)-eicosatrienoate => 8-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoate + H2O


name: cAMP activates EPAC1 (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in) <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Rattus norvegicus)


name: ATP + glycyl-L-asparagine(out) + H2O = ADP + glycyl-L-asparagine(in) + H(+) + phosphate


name: TIMM9:TIMM10 binds hydrophobic proteins (Homo sapiens)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Saccharomyces cerevisiae)


name: Homodimerization  of DFF40 (Drosophila melanogaster)


name: NOX2 generates superoxide anion from oxygen (Rattus norvegicus)


name: intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential


name: lactate + H+ [extracellular] <=> lactate + H+ [cytosol] (Gallus gallus)


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Mus musculus)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Rattus norvegicus)


name: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO2


name: S100A7 or S100A7A binds Zn2+ (Danio rerio)


name: PLK1 binds phosphorylated condensin II complex (Dictyostelium discoideum)


name: 2-oxoglutarate + L-proline + O2 = cis-3-hydroxy-L-proline + CO2 + succinate


name: Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Canis familiaris)


name: eicosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E)-eicosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: (9Z)-octadecenoate + 1-hexadecanoylglycerone 3-phosphate = 1-(9Z)-octadecenoylglycerone 3-phosphate + hexadecanoate


name: H2O + L-4-hydroxyglutamate semialdehyde + NAD(+) => (4S)-4-hydroxy-L-glutamate + 2 H(+) + NADH


name: SLC25A11 exchanges 2-OG and MAL (Caenorhabditis elegans)


name: 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol + 2 Fe(III)-[cytochrome b5] + H2O => 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Mus musculus)


name: SIRT1 deacetylates HINT1 dimer (Gallus gallus)


name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Bos taurus)


name: 3-(methylsulfanyl)propanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> 3-(methylsulfanyl)acryloyl-CoA + reduced [electron-transfer flavoprotein]


name: 3-O-(5'-adenylyl)-L-threonyl-[protein] + H2O = AMP + H(+) + L-threonyl-[protein]


name: PDE4A binds PDE4A inhibitors (Mus musculus)


name: n adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate + 2 H(+) => n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate


name: 2-acetamidofluorene + H2O + NADP(+) = H(+) + N-hydroxy-2-acetamidofluorene + NADPH


name: a 2-hydroxy carboxylate + O2 <=> a 2-oxocarboxylate + H2O2


name: a D-alpha-amino acid + CO2 + NH4(+) => an N-carbamoyl-D-amino acid + 2 H(+) + H2O


name: Activation of highly calcium permeable nicotinic acetylcholine receptors (Mus musculus)


name: NOTCH1 stimulates HES5 transcription (Homo sapiens)


name: acetyl-CoA + N-acetylneuraminate => CoA + N-acetyl-9-O-acetylneuraminate


name: 2-(2-aminophenyl)succinyl-CoA + succinate => (2-aminophenyl)succinate + succinyl-CoA


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Caenorhabditis elegans)


name: H(+) + NADPH + notoamide E + O2 => H2O + NADP(+) + notoamide D


name: adenosine(22) in tRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyladenosine(22) in tRNA + S-adenosyl-L-homocysteine


name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate (Mus musculus)


name: (S)-8-oxocitronellyl enol + NADP(+) => (6E)-8-oxogeranial + H(+) + NADPH


name: acetyl-CoA + N-terminal L-prolyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-prolyl-[protein]


name: (2Z,6Z)-farnesyl diphosphate => beta-acoradiene + diphosphate


name: Resolution of sister chromatids (Canis familiaris)


name: Interaction of Bcl10 to CARMA1 (Bos taurus)


name: ent-copalyl diphosphate => diphosphate + dolabradiene


name: cortisone + NAD(+) = 17alpha-hydroxypregn-4-en-3,11,20-trione-21-al + H(+) + NADH


name: CFTR transits to the plasma membrane (Rattus norvegicus)


name: OSBPL5,8,10 exchange PS with PI4P from ER membrane to plasma membrane (Sus scrofa)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Bos taurus)


name: coelenterazine h + O2 <=> coelenterazine h dioxetanone


name: SHC1 dissociates from integrin alphaIIb beta3 (Bos taurus)


name: Caspase-mediated cleavage of occludin (Canis familiaris)


name: RPE dimers isomerise RU5P to XY5P (Dictyostelium discoideum)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Mus musculus)


name: PAPS is dephosphorylated to APS (Mycobacterium tuberculosis)


name: Exocytosis of secretory granule lumen proteins (Dictyostelium discoideum)


name: Expression of peptide bound class I MHC on cell surface (Danio rerio)


name: monacolin L carboxylate + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + monacolin J carboxylate + oxidized [NADPH--hemoprotein reductase]


name: Nephrin interacts with Podocin (Danio rerio)


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H2O = 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + phosphate


name: N-acetyl-D-glucosamine + O2 <=> H2O2 + N-acetyl-D-glucosamino-1,5-lactone


name: ATP + H2O + L-proline(out) <=> ADP + H(+) + L-proline(in) + phosphate


name: Receptor CCR9  binds CCL25 ligand (Mus musculus)


name: cyclohexane-1-carbonyl-CoA + NADP(+) => cyclohex-1-ene-1-carbonyl-CoA + H(+) + NADPH


name: a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol


name: 9alpha-copalyl diphosphate = diphosphate + stemod-13(17)-ene


name: HIPK2 phosphorylates RUNX1 (Gallus gallus)


name: PA is converted to CDP-DAG by CDS1 (Drosophila melanogaster)


name: VAV exchanges GTP for GDP on RAC1, activating it (Canis familiaris)


name: phosphatidylinositol 3-kinase regulatory subunit binding


name: ARFGAPs stimulate ARF GTPase activity at the Golgi membrane (Gallus gallus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA + H(+)


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O <=> a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)


name: H2O + lanosteryl hexadecanoate <=> H(+) + hexadecanoate + lanosterol


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Bos taurus)


name: (1-deoxy-D-fructos-1-yl)amine + (S)-2-amino-6-oxohexanoate + H2O2 => H2O + N(6)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2


name: a fatty acid + H(+) + sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O


name: 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin + H(+) + L-methionine + NH4(+)


name: CFTR transits to the plasma membrane (Drosophila melanogaster)


name: Efflux of 27-hydroxycholesterol (Homo sapiens)


name: an (11Z,14Z)-icosadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: L-cysteinyl-[protein] + NAD(+) = H(+) + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein]


name: H2O + thiamine triphosphate => H(+) + phosphate + thiamine diphosphate


name: (2E)-hexacosenoyl-CoA + H2O2 => hexacosanoyl-CoA + O2


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Caenorhabditis elegans)


name: Unwinding DNA for the nascent transcript (Dictyostelium discoideum)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(9)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(9)-[histone H3] + succinate


name: a ubiquinol + Na(+)(out) + NAD(+) => a ubiquinone + H(+) + Na(+)(in) + NADH


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Drosophila melanogaster)


name: 2-oxooctadecanoate + H2O2 => 2-hydroxyoctadecanoate + O2


name: H(+) + NADPH + yaequinolone D = H2O + NADP(+) + penigequinolone B


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine = 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: Phosphorylation of MDM4 by CHEK2 (Canis familiaris)


name: O-atom dealkylation of dextromethorphan (Homo sapiens)


name: soyasapogenol A + UDP-alpha-D-glucuronate = H(+) + soyasapogenol A 3-O-beta-D-glucuronate + UDP


name: B3GALTL transfers glucose to O-fucosyl-proteins (Caenorhabditis elegans)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Drosophila melanogaster)


name: chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols (Canis familiaris)


name: 27-hydroxysterol binds ESR1, ESR2 (Xenopus tropicalis)


name: COASY transfers an adenylyl group from ATP to PPANT (Homo sapiens)


name: a ganglioside GD3 + CMP-N-acetyl-beta-neuraminate => a ganglioside GT3 + CMP + H(+)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Saccharomyces cerevisiae)


name: 2,3-dimethylsuccinate(out) + 3 Na(+)(out) => 2,3-dimethylsuccinate(in) + 3 Na(+)(in)


name: PalmS-ESRs:CAVs translocate to plasma membrane (Canis familiaris)


name: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome (Rattus norvegicus)


name: (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] <=> 13-hydroxy-alpha-tocopherol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cholest-4-en-3-one + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = (25R)-3-oxocholest-4-en-26-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one (Sus scrofa)


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Sus scrofa)


name: ADP(out) + AMP(in) => ADP(in) + AMP(out)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Sus scrofa)


name: DYRK2 phosphorylates TP53 (Canis familiaris)


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Xenopus tropicalis)


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Bos taurus)


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Drosophila melanogaster)


name: H(+) + Na(+)(in) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] => Na(+)(out) + NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ESR1:ESTG and EP300 are recruited to TFF3 promoter (Canis familiaris)


name: EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Mus musculus)


name: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] <=> (4S)-perillyl alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein]


name: (E)-4-coumaroyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] = CoA + H(+) + myricetin 3-O-[(6-O-(E)-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: L-histidine + 3 S-adenosyl-L-methionine <=> 3 H(+) + hercynine + 3 S-adenosyl-L-homocysteine


name: Arresten binds integrin alpha1beta1 (Canis familiaris)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Sus scrofa)


name: Phosphorylation of PIP2 to PIP3 by PI3K (Canis familiaris)


name: H2O + methanol + NADP(+) => H(+) + methane + NADPH + O2


name: GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate = GDP + H(+) + methyl 8-{[alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc]oxy}nonanoate


name: an N-(acyl)-sphingosylphosphocholine + H2O => an N-acyl-sphingoid base + H(+) + phosphocholine


name: bis(myo-inositol) 1,3'-phosphate + 2 GDP-alpha-D-mannose <=> 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + 2 GDP + 2 H(+)


name: C20 sphinganine + phosphate => C20 sphinganine 1-phosphate + H2O


name: H(+) + hydroxyacetone + NADH => (S)-propane-1,2-diol + NAD(+)


name: RANBP2 SUMOylates HDAC4 with SUMO2,3 (Mus musculus)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Homo sapiens)


name: 3'-L-prolyl-AMP + holo-[peptidyl-carrier protein] <=> AMP + L-prolyl-[peptidyl-carrier protein]


name: NAGLU hydrolyses Heparan sulfate chain(4) (Homo sapiens)


name: NLK phosphorylates TCF/LEF (Gallus gallus)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: FOXO1 and SIN3A:HDAC complex bind GCK gene promoter (Homo sapiens)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Xenopus tropicalis)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Sus scrofa)


name: a D-alpha-amino acid => an L-alpha-amino acid


name: 5-dehydrofumagillol + H(+) + NADPH => fumagillol + NADP(+)


name: 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Aquaporins passively transport glycerol into cells (Rattus norvegicus)


name: Dephosphorylation of phosphoPFKFB1 by PP2A complex (Homo sapiens)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Gallus gallus)


name: 2,6-dioxo-6-phenylhexanoate + NADP(+) <=> 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH


name: 3-oxochol-4-en-22-oyl-CoA + AMP + diphosphate => 3-oxochol-4-en-22-oate + ATP + CoA


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Xenopus tropicalis)


name: androst-4-ene-3,17-dione + H(+) + NADPH = 5alpha-androstan-3,17-dione + NADP(+)


name: Binding of CBL to EGFR (Drosophila melanogaster)


name: a neolactoside IV(3)-alpha-GalNAc,IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O => a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + N-acetyl-alpha-D-galactosamine


name: (2E)-geranyl diphosphate + umbelliferone = 8-geranylumbelliferone + diphosphate


name: (3R)-hydroxybutanoate dimer + H2O => 2 (R)-3-hydroxybutanoate + H(+)


name: ADP + H(+) + L-valine(in) + phosphate => ATP + H2O + L-valine(out)


name: site-specific DNA-methyltransferase (adenine-specific) activity


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Danio rerio)


name: PTPS is phosphorylated by cGMP-dependant protein kinase II (Sus scrofa)


name: UDP-alpha-D-glucuronate(out) + UDP-alpha-D-xylose(in) => UDP-alpha-D-glucuronate(in) + UDP-alpha-D-xylose(out)


name: Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5) (Canis familiaris)


name: RNF8 and RNF168 ubiquitinate H2AFX (Bos taurus)


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Drosophila melanogaster)


name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + formate => 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + H2O


name: a fatty acid + ATP + H(+) => a fatty acyl-AMP + diphosphate


name: ORC6 is phosphorylated on T195 (Schizosaccharomyces pombe)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Mus musculus)


name: KIR2DS2 interacting with HLA-C group 1 (Cw3) (Sus scrofa)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Sus scrofa)


name: Release of platelet cytosolic components (Caenorhabditis elegans)


name: 2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine = 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate


name: "cobyrinate a,c-diamide synthase (glutamine-hydrolyzing)"


name: Phosphorylated RHOU translocates to the endosome membrane (Xenopus tropicalis)


name: (E)-caffeoyl-CoA + H2O => 3-hydroxy-3-(3,4-dihydroxyphenyl)propanoyl-CoA


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Bos taurus)


name: a 5'-end L-tyrosylphosphate-2'-deoxynucleoside-DNA + H2O => a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+) + L-tyrosine


name: Disassembly of tight junctions (Danio rerio)


name: TAK1 is activated within the TAK1 complex (Sus scrofa)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Schizosaccharomyces pombe)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Drosophila melanogaster)


name: (+)-malbrancheamide D + FADH2 => (+)-malbrancheamide B + bromide + FAD + 2 H(+)


name: hydroxymethylbilane = H2O + uroporphyrinogen III


name: (E)-caffeoylpyruvate + CO2 + hnu => 4-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-1,7-dihydroxy-2,3,5-trioxabicyclo[2.2.2]oct-7-en-6-one


name: 4-imidazolone-5-propanoate <=> H2O + trans-urocanate


name: RAN:GTP recruits nuclear envelope (NE) membranes (Canis familiaris)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + L-serine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phospho-L-serine + ethanolamine


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Canis familiaris)


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate => [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Schizosaccharomyces pombe)


name: Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors (Homo sapiens)


name: 3alpha-hydroxy-5alpha-pregnan-20-one + NAD(+) <=> 5alpha-pregnane-3,20-dione + H(+) + NADH


name: decanoyl-CoA + L-seryl-[protein] <=> CoA + O-decanoyl-L-seryl-[protein]


name: a (Z)-N-(sulfonatooxy)alkanimidothioate = a nitrile + sulfate + sulfur


name: (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate + H2O = (R)-glycerate + alpha-D-mannose 6-phosphate


name: RUNX2 binds HEY1,HEY2,HES1 (Homo sapiens)


name: dihydropyrimidine dehydrogenase (NAD+) activity


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Danio rerio)


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Mus musculus)


name: SRC-1 phosphorylates p-Y397-PTK2 (Rattus norvegicus)


name: an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine => a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine


name: folate + H(+) + NADPH => 7,8-dihydrofolate + NADP(+)


name: beta-tocotrienol + H(+) + S-adenosyl-L-homocysteine => delta-tocotrienol + S-adenosyl-L-methionine


name: beta-alanyl-[peptidyl-carrier protein] + tryptamine => beta-alanyl-tryptamine + H(+) + holo-[peptidyl-carrier protein]


name: MAP1LC3B binds KEAP1 and SQSTM1 (Canis familiaris)


name: CBL binds TGFBR2 (Drosophila melanogaster)


name: dUTP + H2O => dUMP + pyrophosphate (Rattus norvegicus)


name: 4 norrubrofusarin + O2 <=> 2 H2O + 2 ustilaginoidin A


name: Interleukin-5 receptor alpha subunit binds Interleukin-5 (Gallus gallus)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Sus scrofa)


name: Exocytosis of specific granule membrane proteins (Sus scrofa)


name: ECHS1 hydrates methacrylyl-CoA (Bos taurus)


name: Activated TP receptor binds G-protein  G13 (Xenopus tropicalis)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-(hexanoyl)sphing-4-enine + O2 <=> 2 Fe(III)-[cytochrome b5] + 2 H2O + N-hexanoyl-sphinga-4E,14Z-dienine


name: SUMOylation of DDX17 with SUMO1 (Saccharomyces cerevisiae)


name: an aryl sulfate + H2O = a phenol + H(+) + sulfate


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Xenopus tropicalis)


name: PLK1 phosphorylates GORASP1 (Mus musculus)


name: 2xPPCS ligates PPanK with Cys (Rattus norvegicus)


name: H(+)(in) + N-acetyl-L-aspartyl-L-glutamate(in) => H(+)(out) + N-acetyl-L-aspartyl-L-glutamate(out)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Danio rerio)


name: H2O + O-phospho-L-threonine => L-threonine + phosphate


name: a fatty aldehyde + phosphoethanolamine => a sphingoid 1-phosphate


name: Formation of ADAR1 homodimer (Sus scrofa)


name: Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Gallus gallus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Sus scrofa)


name: 3-oxohexanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyhexanoyl-[ACP] + NADP(+)


name: Activation of BAD by calcineurin (Sus scrofa)


name: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol (Sus scrofa)


name: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine


name: abieta-7,13-dien-18-ol + O2 + reduced [NADPH--hemoprotein reductase] => abieta-7,13-dien-18,18-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ganglioside GT1b (d18:1(4E)/18:0) + H2O = ganglioside GD1b(d18:1(4E)/18:0) + N-acetylneuraminate


name: L-aspartate(in) + L-glutamine(out) = L-aspartate(out) + L-glutamine(in)


name: H(+) + sulfite + UDP-alpha-D-glucose <=> H2O + UDP-alpha-D-6-sulfoquinovose


name: 8-oxo-dGMP + H(+) + phosphate => 8-oxo-dGDP + H2O


name: alpha-D-ribose 1,5-bisphosphate <=> D-ribulose 1,5-bisphosphate


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Dictyostelium discoideum)


name: Formation of the SET1B complex (Homo sapiens)


name: Activated FGFR4 phosphorylates FRS2 (Canis familiaris)


name: NUDT12 hydrolyses NADH to NMNH (Bos taurus)


name: (indol-3-yl)butanoate + ATP + L-glutamine => (indol-3-yl)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: (9S,10R)-epoxy-octadecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-(9S,10R)-epoxy-octadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: LGI1 binds ADAM22 and ADAM23 (Homo sapiens)


name: ATG10 dissociates from ATG12:ATG5 (Homo sapiens)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + H(+) + NADPH = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP(+)


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Mus musculus)


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ethanol + o-quinone methide = hydroxyclavatol ethyl ether


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Rattus norvegicus)


name: D-xylulose + H(+) + NADH => NAD(+) + xylitol


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Caenorhabditis elegans)


name: SOX17 and TFAP2C bind the PRDM1 gene (Homo sapiens)


name: H2O + omega-dicarboxyl-CoA = a dicarboxylate + CoA + H(+)


name: Budding of COPII coated vesicle (Gallus gallus)


name: IL12B:IL23A translocates from ER lumen to extracellular space (Mus musculus)


name: (2E)-octadecenoyl-[ACP] + H(+) + NADPH <=> NADP(+) + octadecanoyl-[ACP]


name: [phosphate](n) + GTP = [phosphate](n+1) + GDP


name: 1-O-hexadecyl-2-amino-sn-glycerol + ATP = 1-O-hexadecyl-2-desoxy-2-amino-sn-glycero-3-phosphate + ADP + H(+)


name: 2 Fe(II)-[cytochrome b5] + H(+) + NADP(+) => 2 Fe(III)-[cytochrome b5] + NADPH


name: a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E)) + H(+) + UDP => a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP-alpha-D-galactose


name: ADRM1:26S proteaseome binds UCHL5 (Schizosaccharomyces pombe)


name: CYP26C1 4-hydroxylates 9cRA (Gallus gallus)


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + succinate


name: 5-S-cysteinyldopa + L-dopaquinone => 5-S-cysteinyldopaquinone + L-dopa


name: 2 H(+) + 2 malonyl-CoA + octadecanoyl-CoA => 4-hydroxy-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Danio rerio)


name: H(+) + reticuline + S-adenosyl-L-homocysteine => norreticuline + S-adenosyl-L-methionine


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Mus musculus)


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Danio rerio)


name: AXL binds SRC-1 (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate + H2O => (6E)-nerolidol + diphosphate


name: p-S10 CDKN1B translocates to the cytosol (Drosophila melanogaster)


name: MLCL is acylated to CL by LCLAT1 (ER) (Danio rerio)


name: L-glutamate(out) + taurocholate(in) => L-glutamate(in) + taurocholate(out)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Sus scrofa)


name: 2-O-(alpha-D-glucopyranosyl)-sn-glycerol 3-phosphate + ADP + H(+) => ADP-alpha-D-glucose + sn-glycerol 3-phosphate


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Drosophila melanogaster)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Rattus norvegicus)


name: an (R)-2-haloacid + H2O <=> a (2R)-2-hydroxycarboxylate + a halide anion + H(+)


name: TLR4-induced ripoptosome assembly (Bos taurus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = an N-acylsphing-4-enine + cholesteryl 3-beta-D-glucoside


name: H2O + N-tetradecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-tetradecanoylethanolamine


name: esculetin + S-adenosyl-L-methionine = H(+) + isoscopoletin + S-adenosyl-L-homocysteine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: succinylCoA + GDP + Pi <=> succinate + CoASH + GTP (Gallus gallus)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Mus musculus)


name: docosanoate + taurine => H2O + N-docosanoyl-taurine


name: Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Mus musculus)


name: MDM2 translocates to the cytosol (Homo sapiens)


name: Soluble PROCR binds activated protein C (Mus musculus)


name: (R)-dihydrolipoate + ATP + H(+) = diphosphate + N(6)-[(R)-dihydrolipoyl]-5'-AMP


name: CHUK, IKBKB and IKBKG form IKK complex (Sus scrofa)


name: tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex (Bos taurus)


name: CLN3 transports GalCer to plasma membrane (Schizosaccharomyces pombe)


name: a (2E)-enoyl-CoA + H2O => a (3S)-3-hydroxyacyl-CoA


name: T1R1/T1R3 dimer is the umami taste receptor (Homo sapiens)


name: Rag dimer formation (Caenorhabditis elegans)


name: PDE6 hydrolyses cGMP to GMP (Xenopus tropicalis)


name: LAG3 (CD233) binds MHC II (Canis familiaris)


name: ALD3A1 oxidises 4HPCP to CXPA (Caenorhabditis elegans)


name: H(+)(in) + N-(4-aminobenzoyl)-L-glutamate(in) = H(+)(out) + N-(4-aminobenzoyl)-L-glutamate(out)


name: RFC dissociates after sliding clamp formation (Plasmodium falciparum)


name: DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Canis familiaris)


name: 3-O-methylgallate + O2 => 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + methanol


name: NADP(+) + reduced coenzyme F420-(gamma-L-Glu)(n) <=> 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: ADP + bacteriochlorophyllide g + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate <=> 3,8-divinyl chlorophyllide a + ATP + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine => H(+) + lipid A disaccharide (E. coli) + UDP


name: cyclohexylamine + H2O + NAD(+) <=> cyclohexanone + H(+) + NADH + NH4(+)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Homo sapiens)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)


name: ADRM1 binds 26S proteasome (Dictyostelium discoideum)


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Danio rerio)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(out) + a dicarboxylate(in) => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin(in) + a dicarboxylate(out)


name: CYP2D6 4-hydroxylates debrisoquine (Sus scrofa)


name: H2O + L-serine + O2 => 3-hydroxypyruvate + H2O2 + NH4(+)


name: trans-Golgi Network Coat Activation (Mus musculus)


name: KIT mutants bind ripretinib (Homo sapiens)


name: MECP2 is phosphorylated at S423 (Homo sapiens)


name: cortisone + NAD(+) => 17alpha-hydroxypregn-4-en-3,11,20-trione-21-al + H(+) + NADH


name: an aromatic carboxylate + 2 H(+) + NADH => an aromatic aldehyde + H2O + NAD(+)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-gamma-aminobutanoate


name: 2-deoxyecdysone 22-phosphate + H2O => 2-deoxyecdysone + phosphate


name: Phosphorylated PXN recruits the CRK complex (Sus scrofa)


name: 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(34) in tRNA + S-adenosyl-L-methionine


name: B-RAF dissociates from S111/S120 p-SPRY2 (Sus scrofa)


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + CoA


name: FUT1,2 transfer fucose to gangliosides (Xenopus tropicalis)


name: (2-hydroxyphenyl)acetate + CO2 => 3-phenylpyruvate + O2


name: p-S MAPK6,4 phosphorylate MAPKAPK5 (Mus musculus)


name: Binding of SHC1 to p-6Y-EGFR mutants (Homo sapiens)


name: AMP(in) + NAD(+)(out) => AMP(out) + NAD(+)(in)


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Schizosaccharomyces pombe)


name: Phosphorylated MAPKs phosphorylate ATF-2 (Gallus gallus)


name: H(+) + N(2)-(ADP-D-ribosyl)-guanine + nicotinamide => guanine + NAD(+)


name: Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-diphosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + phosphate


name: 4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate


name: CO2 + 2 Fe(II)-[cytochrome b1] + H(+) => 2 Fe(III)-[cytochrome b1] + formate


name: Binding of TFIIIA To type 1 Promoter (Danio rerio)


name: a 1,1-dimethyl-3-phenylurea + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-methyl-3-phenylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Phosphorylated SHC recruits GRB2:SOS1 (Bos taurus)


name: dihydrocarveol + NAD(+) = dihydrocarvone + H(+) + NADH


name: (R)-noradrenaline(in) + chloride(in) + Na(+)(in) => (R)-noradrenaline(out) + chloride(out) + Na(+)(out)


name: 2 N(omega)-hydroxy-L-arginine + NADPH + 2 O2 <=> H(+) + 2 H2O + 2 L-citrulline + NADP(+) + 2 nitric oxide


name: GRB2 is indirectly recruited to p-KIT through SHP2 (Canis familiaris)


name: SRPK1/2 phosphorylates nucleoprotein (Homo sapiens)


name: CYP7A1 7-hydroxylates CHOL (Mus musculus)


name: ANO1 transports cytosolic Cl- to extracellular region (Sus scrofa)


name: 5alpha-androstane-3beta,17beta-diol + NADP(+) => 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH


name: a (Z)-omega-(methylsulfanyl)-N-sulfo-alkylhydroximate S-glucoside + H(+) + NADPH + O2 = a (Z)-omega-(methylsulfinyl)-alkyl-glucosinolate + H2O + NADP(+)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA => 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Sus scrofa)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Canis familiaris)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Schizosaccharomyces pombe)


name: Formation of AT-AC C complex (Xenopus tropicalis)


name: CLDN5 (Claudin-5) gene expression is stimulated by RUNX1 (Homo sapiens)


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Sus scrofa)


name: SH2 domain of Src binds to the active receptor (Rattus norvegicus)


name: Formation of hRSV A dsRNA intermediate form (Homo sapiens)


name: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine <=> 7,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine


name: Phosphorylation of SLP-76 by p-SYK (Sus scrofa)


name: 3-hydroxyanthranilate + H(+) + L-alanine => 3-hydroxy-L-kynurenine + H2O


name: RAC3 GAPs stimulate RAC3 GTPase activity (Canis familiaris)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Homo sapiens)


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Rattus norvegicus)


name: butanal + H(+) + NADH => butan-1-ol + NAD(+)


name: 9alpha-copalyl diphosphate = diphosphate + stemar-13-ene


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + NAD(+) => 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + H(+) + NADH


name: a 1-O-alkyl-2-acetyl-sn-glycerol + an acyl-CoA => a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Homo sapiens)


name: acetyl-AMP + cytidine(34) in elongator tRNA(Met) <=> AMP + H(+) + N(4)-acetylcytidine(34) in elongator tRNA(Met)


name: ATP + CoA + decanoate => AMP + decanoyl-CoA + diphosphate


name: Tyrosine is monoiodinated (Homo sapiens)


name: KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Rattus norvegicus)


name: MAOB:FAD oxidatively deaminates TYR (Sus scrofa)


name: 1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: POFUT2 transfers fucose to TSR domain-containing proteins (Mus musculus)


name: The acetyl group from acetyl-CoA is transferred to the NAT1 (Bos taurus)


name: DEGS1 dehydrogenates dihydroceramide (Danio rerio)


name: Granzyme-B activates BID by cleavage (Gallus gallus)


name: Budding of connexon-containing transport vesicles from the Golgi (Homo sapiens)


name: AMOT proteins bind WWTR1 (TAZ) (Danio rerio)


name: 2 H2O + iminodiacetonitrile => N-(cyanomethyl)glycine + NH4(+)


name: PHGDH tetramer dehydrogenates 3PG (Bos taurus)


name: SARS-CoV-2 3a binds to UVRAG (Homo sapiens)


name: 7(1)-hydroxychlorophyllide a + NAD(+) => chlorophyllide b + H(+) + NADH


name: Binding of GRB2:SOS1 complex to phosphorylated EGFRvIII (Homo sapiens)


name: SMAC (DIABLO) binds XIAP (Gallus gallus)


name: S-adenosyl-L-methionine + tellurite <=> methanetellurite + S-adenosyl-L-homocysteine


name: H2O + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] => 3-deoxyglucosone + L-lysyl-[protein] + phosphate


name: acetyl-CoA + L-2,4-diaminobutanoate => (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: hexadecanedioyl-CoA + O2 <=> (2E)-hexadecenedioyl-CoA + H2O2


name: K63polyUb-TAK1 autophosphorylates (Bos taurus)


name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Mus musculus)


name: RBX1:CUL3 dissociates from forming autophagosome (Drosophila melanogaster)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Mus musculus)


name: 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: (Z)-phenylacetaldehyde oxime => H2O + phenylacetonitrile


name: SHC1 phosphorylation by ERBB2 heterodimers (Sus scrofa)


name: (S)-norreticuline + S-adenosyl-L-methionine = (S)-norcodamine + H(+) + S-adenosyl-L-homocysteine


name: H2O + N-(9Z-octadecenoyl)-L-tyrosine => (9Z)-octadecenoate + L-tyrosine


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Danio rerio)


name: Dephosphorylation of p-Y-IRS1,p-Y-IRS2 (Homo sapiens)


name: Na(+)(out) + uridine(out) = Na(+)(in) + uridine(in)


name: Aquaporin-7 passively transports glycerol out of cell (Canis familiaris)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(out) + ADP + H(+) + phosphate


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Homo sapiens)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Homo sapiens)


name: RET binds GFRA1,GFRA3 (Rattus norvegicus)


name: beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Drosophila melanogaster)


name: PDP1,2 dephosphorylate p-lipo-PDH (Bos taurus)


name: epothilone D + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => epothilone B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Danio rerio)


name: GDP-beta-L-fucose + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate => GDP + H(+) + methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Mus musculus)


name: (2E)-octadecenoyl-CoA + H2O => (3S)-hydroxyoctadecanoyl-CoA


name: Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Mus musculus)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Gallus gallus)


name: a 1,2-diacylglycerol + H2O => a 2-acylglycerol + a fatty acid + H(+)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Plasmodium falciparum)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Sus scrofa)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Rattus norvegicus)


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl beta-D-glucuronate(in) + ATP + H2O <=> 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl beta-D-glucuronate(out) + ADP + H(+) + phosphate


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Mus musculus)


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Schizosaccharomyces pombe)


name: coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Activated FGFR1 phosphorylates FRS2 (Bos taurus)


name: SYK binds the activated BCR (Rattus norvegicus)


name: FMNH2 + nitrilotriacetate + O2 = aminodiacetate + FMN + glyoxylate + H2O


name: NRXNs bind CASK:Protein 4.1 (Sus scrofa)


name: a globoside Gb3Cer + H(+) + UDP => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose


name: 2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol


name: D-mannitol + NAD(+) = D-fructose + H(+) + NADH


name: [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n) + n ATP + n D-aspartate <=> [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + n ADP + n H(+) + n phosphate


name: POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 (Rattus norvegicus)


name: PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Canis familiaris)


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Plasmodium falciparum)


name: mRNP complex dissociates from cytosolic face of NPC (Gallus gallus)


name: H(+) + NADPH + uridine(17) in tRNA => 5,6-dihydrouridine(17) in tRNA + NADP(+)


name: NOTUM releases Hh-Np:GPC5 from the plasma membrane (Canis familiaris)


name: ATP + beta-alanine + gamma-L-glutamyl-L-cysteine = ADP + gamma-L-glutamyl-L-cysteinyl-beta-alanine + H(+) + phosphate


name: PRKD1,2,3 phosphorylates CERT1-2 (Danio rerio)


name: AMPK phosphorylates TP53 (Drosophila melanogaster)


name: MeSeO2H is reduced to MeSeOH by TXNRD1 (Plasmodium falciparum)


name: Dissociation of the Gi alpha:G olf complex (Bos taurus)


name: H(+) + S-adenosyl-L-homocysteine + vanillate => 3,4-dihydroxybenzoate + S-adenosyl-L-methionine


name: A + a 1-hydroxy-3-oxo steroid <=> a steroid 1,3-dione + AH2


name: D-mannose(out) + H(+)(out) => D-mannose(in) + H(+)(in)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Plasmodium falciparum)


name: RPE dimers isomerise RU5P to XY5P (Plasmodium falciparum)


name: a ubiquinol + 2 O2 => a ubiquinone + 2 H(+) + 2 superoxide


name: AKT phosphorylates FOXO1A (Homo sapiens)


name: ITP + oxaloacetate = CO2 + IDP + phosphoenolpyruvate


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Dictyostelium discoideum)


name: (2S)-3-sulfolactaldehyde + H2O + NADP(+) => (2S)-3-sulfolactate + 2 H(+) + NADPH


name: 2-carboxy-L-lyxonate + H(+) = CO2 + L-lyxonate


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Dictyostelium discoideum)


name: PDE5A dimer binds PDE5A inhibitors (Bos taurus)


name: ITPA hydrolyses dITP to dIMP (Schizosaccharomyces pombe)


name: D-leucine + H2O + O2 = 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: DHFR dimer binds DHFR inhibitors (Caenorhabditis elegans)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Sus scrofa)


name: 1-O-alkyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-alkyl-sn-glycero-3-phosphate + choline + H(+)


name: H2O + N-(15Z-tetracosenoyl)-taurine = (15Z)-tetracosenoate + taurine


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Rattus norvegicus)


name: H2O + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + NADP(+) => H(+) + Mg-protoporphyrin IX 13-monomethyl ester + NADPH + O2


name: eicosanoyl-CoA + H(+) + malonyl-CoA <=> 3-oxodocosanoyl-CoA + CO2 + CoA


name: H(+) + ipsdienone + NADPH => (4R)-ipsdienol + NADP(+)


name: ISGylation of host protein filamin B (Caenorhabditis elegans)


name: 11-hydroxyferruginol + O2 + reduced [NADPH--hemoprotein reductase] = 11,20-dihydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: loading of Serotonin in synaptic vesicles (Rattus norvegicus)


name: 17beta-estradiol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 17beta-estradiol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate


name: NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP (Gallus gallus)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Schizosaccharomyces pombe)


name: a dicarboxylate(in) + L-sepiapterin(out) <=> a dicarboxylate(out) + L-sepiapterin(in)


name: (-)-minovincinine + acetyl-CoA <=> (-)-echitovenine + CoA


name: Formation of the SET1A complex (Rattus norvegicus)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Sus scrofa)


name: Abortive Initiation Before Second Transition (Schizosaccharomyces pombe)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Schizosaccharomyces pombe)


name: AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Bos taurus)


name: 26-deglucoprotodioscin + D-glucose => H2O + protodioscin


name: (2E,6E)-farnesyl diphosphate <=> (S)-beta-bisabolene + diphosphate


name: factor Va + factor Xa -> Va:Xa complex (prothrombinase) (Gallus gallus)


name: Ragulator binds Rag dimers (Canis familiaris)


name: Na(+)(out) + propanoate(out) = Na(+)(in) + propanoate(in)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O => 2-(9Z-octadecenoyl)-3-hexadecanoyl-sn-glycerol + H(+) + hexadecanoate


name: ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA (Bos taurus)


name: H2O + NAD(+) + serinol <=> dihydroxyacetone + H(+) + NADH + NH4(+)


name: AGT(34-41) binds to AGTR1 (Caenorhabditis elegans)


name: 3'-phosphoadenylyl sulfate + androsterone <=> adenosine 3',5'-bisphosphate + androsterone 3alpha-sulfate + H(+)


name: LIG1, APEX1 and PCNA:POLD,POLE:RPA:RFC dissociate from repaired DNA (Homo sapiens)


name: PA is dephosphorylated to DAG by LPIN (Homo sapiens)


name: FA anion diffuses laterally to UCP (Canis familiaris)


name: glycolate + NADP(+) => glyoxylate + H(+) + NADPH


name: 2-all-trans-octaprenylphenol + H(+) + NADPH + O2 = 3-(all-trans-octaprenyl)benzene-1,2-diol + H2O + NADP(+)


name: Phosphorylation of YAP by LATS1 (Caenorhabditis elegans)


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Bos taurus)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + CMP-N-acetyl-beta-neuraminate => a ganglioside GM3 + CMP + H(+)


name: UCHL3, SENP8 cleave NEDD8 (Schizosaccharomyces pombe)


name: amicoumacin A + phosphate => amicoumacin A 2-phosphate + H2O


name: 3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine => 4',7,8-trihydroxy-3'-methoxyflavone-7-olate + H(+) + S-adenosyl-L-homocysteine


name: NADSYN1 hexamer amidates NAAD to NAD+ (Plasmodium falciparum)


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Homo sapiens)


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Schizosaccharomyces pombe)


name: Neogenin binds repulsive guidance molecules (RGDs) (Homo sapiens)


name: Formation of the RBBP5:ASH2L heterodimer (Rattus norvegicus)


name: (+)-copalyl diphosphate <=> (12E)-labda-8(17),12,14-triene + diphosphate


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Mus musculus)


name: p-PKR dimer phosphorylates PPP2R5A (Caenorhabditis elegans)


name: SLC25A18,22 import L-Glu, H+ (Homo sapiens)


name: ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Homo sapiens)


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Xenopus tropicalis)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)


name: H(+) + phylloquinol + S-adenosyl-L-homocysteine => demethylphylloquinol + S-adenosyl-L-methionine


name: Ubiquitinated TP53 translocates to the cytosol (Danio rerio)