name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Sus scrofa)


name: ATPase activity, coupled to transmembrane movement of ions, rotational mechanism


name: USP1:WDR48 binds monoUb:K164-PCNA (Danio rerio)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Sus scrofa)


name: Exocytosis of azurophil granule membrane proteins (Mus musculus)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Bos taurus)


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Schizosaccharomyces pombe)


name: [eIF5A protein]-N-(4-aminobutylidene)-L-lysine + H(+) + NADH <=> [eIF5A protein]-deoxyhypusine + NAD(+)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate <=> 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: SLC22A18 exchanges extracellular organic cations for cytosolic H+ (Xenopus tropicalis)


name: ethanol + NAD(+) <=> acetaldehyde + H(+) + NADH


name: quillate + UDP-alpha-D-glucose = quillaic acid 28-beta-D-glucoside + UDP


name: (2E,6E)-farnesyl phosphate + H2O => (2E,6E)-farnesol + phosphate


name: ATM phosphorylates EYA1-4 (Mus musculus)


name: glycine(out) + H(+)(in) + Na(+)(out) => glycine(in) + H(+)(out) + Na(+)(in)


name: D-serine(in) + L-alanine(out) + Na(+)(out) => D-serine(out) + L-alanine(in) + Na(+)(in)


name: calcium-dependent protein serine/threonine phosphatase regulator activity


name: Activation of BAD by calcineurin (Homo sapiens)


name: Complement factor I inactivates surface-bound C3b (Gallus gallus)


name: palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine (Drosophila melanogaster)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Canis familiaris)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Homo sapiens)


name: AH2 + prostaglandin G3 <=> A + H2O + prostaglandin H3


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Bos taurus)


name: BRWD1 binds SMARCA4 (Xenopus tropicalis)


name: FMNH2 + N-methylnicotinate + O2 => (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+)


name: SPTLC complexes transfer acyl-CoA onto serine (Canis familiaris)


name: 2-oxoglutarate + 3,3',5-triiodo-L-thyronine => 3,5,3'-triiodothyropyruvate + L-glutamate


name: (R)-1-phenylethanol + NADP(+) => acetophenone + H(+) + NADPH


name: 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide => H2O + IMP


name: diphosphate + RNA(n+1) => a ribonucleoside 5'-triphosphate + RNA(n)


name: 3-methylbutanal + H2O + NADP(+) => 3-methylbutanoate + 2 H(+) + NADPH


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin. (Gallus gallus)


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Bos taurus)


name: Binding of PI3K to complex of GRB2:GAB1 and p-EGFRvIII (Homo sapiens)


name: Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)


name: Cytosolic folate export across the plasma membrane (Mus musculus)


name: GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Rattus norvegicus)


name: 4-hydroxybenzyl alcohol + 2 H(+) + 2 reduced [azurin] => 4-methylphenol + H2O + 2 oxidized [azurin]


name: 9H-carbazole + H(+) + NADH + O2 => 2'-aminobiphenyl-2,3-diol + NAD(+)


name: dAMP + H2O => 2-deoxy-D-ribose 5-phosphate + adenine


name: butanal + hydrogen cyanide = (2S)-2-hydroxypentanenitrile


name: Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)


name: SRC phosphorylates RUNX3 (Rattus norvegicus)


name: 1-acyl LPG is acylated to PG by LPGAT (Sus scrofa)


name: CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated (Sus scrofa)


name: ERBB2 promotes PTK6 autophosphorylation (Rattus norvegicus)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Sus scrofa)


name: (Z)-2-methylureidoacrylate + FMN + H(+) + H2O + NAD(+) => FMNH2 + NADH + O2 + thymine


name: HSD17B3-like proteins reducde ANDST to TEST (Sus scrofa)


name: 3-aminoavenalumate + ATP + H(+) + nitrite => 3-diazoavenalumate + AMP + diphosphate + H2O


name: Displacement of UNG glycosylase by APEX1 at the AP site (Homo sapiens)


name: (2R,3S)-beta-methylmalyl-CoA = 2-methylfumaryl-CoA + H2O


name: H2O + indole-3-acetaldehyde + NAD(+) <=> (indol-3-yl)acetate + 2 H(+) + NADH


name: Beta-Pix:CDC42:GTP binds CBL in EGF:p-6Y-EGFR:CBL:CIN85 (Gallus gallus)


name: (+)-nootkatone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => alpha-nootkatol + O2 + reduced [NADPH--hemoprotein reductase]


name: H2O + N(2)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2 = (1-deoxy-D-fructos-1-yl)amine + 6-amino-2-oxohexanoate + H2O2


name: 1-octadecanoyl-sn-glycero-3-phosphoserine + 10-hydroxyoctadecanoate + H(+) => 1-octadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O


name: RAC2 GAPs stimulate RAC2 GTPase activity (Mus musculus)


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Danio rerio)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Rattus norvegicus)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Danio rerio)


name: (E)-feruloyl-CoA + H2O <=> (E)-ferulate + CoA + H(+)


name: MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Canis familiaris)


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Rattus norvegicus)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Sus scrofa)


name: G alpha (12) binds BTK (Drosophila melanogaster)


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Rattus norvegicus)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Bos taurus)


name: a long-chain fatty acid + ATP + L-cysteinyl-[protein] => AMP + diphosphate + S-(long-chain fatty acyl)-L-cysteinyl-[protein]


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 <=> 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: (E)-feruloyl-CoA + L-quinate => 4-O-feruloyl-D-quinate + CoA


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Bos taurus)


name: CCACCA tRNA nucleotidyltransferase activity


name: Fibrillin-1 degradation by MMP14 (Homo sapiens)


name: 16alpha-hydroxygypsogenate 28-beta-D-glucoside + UDP => 16alpha-hydroxygypsogenate + UDP-alpha-D-glucose


name: (2E,6E)-farnesyl diphosphate = (-)-7-epi-alpha-selinene + diphosphate


name: IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Sus scrofa)


name: L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: (1S,4R)-fenchone + H(+) + NADH => (1S,2S,4R)-endo-fenchol + NAD(+)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Caenorhabditis elegans)


name: Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Canis familiaris)


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Sus scrofa)


name: Caspase-mediated cleavage of PKC theta (Bos taurus)


name: an L-glycol + NADP(+) = a 2-hydroxycarbonyl + H(+) + NADPH


name: Active FLT3 binds to SOCS2 (Mus musculus)


name: ADD1:ADD3 binds DMTN (Drosophila melanogaster)


name: (2S)-2-hydroxy-2-(thiophen-3-yl)acetonitrile => 3-formylthiophene + hydrogen cyanide


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Saccharomyces cerevisiae)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)


name: RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Sus scrofa)


name: (5Z,8Z)-eicosadienoate + O2 <=> (5S)-hydroperoxy-(6E,8Z)-eicosadienoate


name: CDK5R1 gene expression is stimulated by NPAS4 (Homo sapiens)


name: L-histidine + S-adenosyl-L-methionine => (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Mus musculus)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Mus musculus)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Saccharomyces cerevisiae)


name: (6E)-8-hydroxygeraniol + NAD(+) <=> (6E)-8-hydroxygeranial + H(+) + NADH


name: Thyrotropin-releasing hormone receptor binds thyrotropin (Homo sapiens)


name: 1,2-dioctanoyl-sn-glycero-3-phosphate + H2O => 1,2-dioctanoyl-sn-glycerol + phosphate


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Drosophila melanogaster)


name: H(+) + NADP(+) + 2 reduced [rubredoxin] = NADPH + 2 oxidized [rubredoxin]


name: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an (11E)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (17R,20S)-17,20-dihydroxypregn-4-en-3-one + NAD(+) = 17alpha-hydroxyprogesterone + H(+) + NADH


name: IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Canis familiaris)


name: ADP + H(+) + N(tele)-phospho-L-histidyl-[protein] => ATP + L-histidyl-[protein]


name: nicotinate transmembrane transporter activity


name: SLC22A13 transports NCA from extracellular region to cytosol (Homo sapiens)


name: p-STAT1:p-STAT4 translocates to the nucleus (Sus scrofa)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADH + O2 <=> 4beta-hydroxymethyl-4alpha-methylzymosterol + H2O + NAD(+)


name: p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 (Sus scrofa)


name: (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) => 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + H(+) + NADH


name: A + all-trans-13,14-dihydroretinol => AH2 + all-trans-retinol


name: RHOT1 hydrolyzes GTP (Drosophila melanogaster)


name: Defective NAGLU does not hydrolyse heparan chain(2) (Homo sapiens)


name: (8Z,11Z,14Z)-eicosatrienamide + H2O <=> (8Z,11Z,14Z)-eicosatrienoate + NH4(+)


name: Defective EPM2A does not dephosphorylate phosphoglycogen (type 2A disease) (Homo sapiens)


name: RRAGA,B exchanges GDP for GTP (Caenorhabditis elegans)


name: ATP + H2O + L-selenomethionine => diphosphate + L-adenosylselenomethionine + phosphate


name: DCC interaction with SIAH1 (Danio rerio)


name: (2E,6E)-farnesyl diphosphate = (-)-alpha-isocomene + diphosphate


name: 4-phospho-D-erythronate + NAD(+) => 3-dehydro-4-O-phospho-D-erythronate + H(+) + NADH


name: (R)-pantothenate + H2O = (R)-pantoate + beta-alanine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + reduced [electron-transfer flavoprotein]


name: all-trans-4-oxoretinol + NAD(+) = all-trans-4-oxoretinal + H(+) + NADH


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Gallus gallus)


name: 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+) => 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP


name: H2O + trithionate => H(+) + sulfate + thiosulfate


name: Assembly of IFT A complex (Canis familiaris)


name: Formation of Okazaki fragments (Caenorhabditis elegans)


name: SMAC (DIABLO) forms dimer (Xenopus tropicalis)


name: lutein + O2 => (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R,6R)-hydroxy-alpha-ionone


name: FUT3 transfers Fuc to Type 1 DSGG to form dsLeA (Xenopus tropicalis)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Drosophila melanogaster)


name: MTMR12 binds MTM1 (Schizosaccharomyces pombe)


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H(+) + NADPH => (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: FADH2 + NADP(+) <=> FAD + 2 H(+) + NADPH


name: AKR1B15 reduces EST17b to E1 (Danio rerio)


name: GLI translocates to the nucleus (Homo sapiens)


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Gallus gallus)


name: Phosphorylation of INFAR1 by TYK2 (Xenopus tropicalis)


name: Exocytosis of Proactivator polypeptide (Drosophila melanogaster)


name: Fe3+ dissociates from holoTF:TFRC dimer (Mus musculus)


name: nonanoyl-CoA + O2 <=> (2E)-nonenoyl-CoA + H2O2


name: type 2 metabotropic glutamate receptor binding


name: NSF ATPase activity dissociates cis-SNARE at the ER (Caenorhabditis elegans)


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Canis familiaris)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Xenopus tropicalis)


name: EPHB2 binds KALRN (Caenorhabditis elegans)


name: L-aspartate(in) + L-cystine(out) = L-aspartate(out) + L-cystine(in)


name: WNT5A:FZD4 is endocytosed (Canis familiaris)


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Dictyostelium discoideum)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Rattus norvegicus)


name: (2E)-geranyl diphosphate + L-glutamate => diphosphate + N-geranyl-L-glutamate


name: histone H4K12 acetyltransferase activity


name: Corticosteroids bind to CBG in blood (Caenorhabditis elegans)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Caenorhabditis elegans)


name: 11-hydroxyferruginol + O2 + reduced [NADPH--hemoprotein reductase] <=> 11,20-dihydroxyferruginol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (3S)-versiconol acetate + NADP(+) => (2S,3S)-versiconal hemiacetal acetate + H(+) + NADPH


name: Synthesis of PIP3 from PIP2 by PI3K (Mus musculus)


name: Salvage - Sepiapterin is reduced to BH2 (Homo sapiens)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Bos taurus)


name: Hemes bind to CLEC1B dimer (Mus musculus)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Sus scrofa)


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Drosophila melanogaster)


name: (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH


name: a 5'-end dephospho-2'-deoxyribonucleoside-DNA + ATP = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + ADP + H(+)


name: Formation of CSL NCOR corepressor complex (Homo sapiens)


name: HuR binds mRNAs in the nucleus (Xenopus tropicalis)


name: ARFGAPs stimulate ARF GTPase activity (Rattus norvegicus)


name: 7-methylxanthosine + H2O = 7-methylxanthine + D-ribose + H(+)


name: Release of 40S and 60S subunits from the 80S ribosome  (Bos taurus)


name: Zinc is an agonist of GPR39 (Sus scrofa)


name: ATP + L-threonine = diphosphate + L-threonyl-5'-AMP


name: L-arginine(out) + L-cystine(in) => L-arginine(in) + L-cystine(out)


name: USP14 deubiquitinates NLRC5 (Rattus norvegicus)


name: Receptor CCR9  binds CCL25 ligand (Homo sapiens)


name: N-acetyl-D-glucosamine + UDP-alpha-D-galactose <=> beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + H(+) + UDP


name: D-ribitol 5-phosphate + H2O <=> phosphate + ribitol


name: [deoxyhypusine synthase]-L-lysine + [eIF5A protein]-N-(4-aminobutylidene)-L-lysine => [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + [eIF5A protein]-L-lysine


name: 4-hydroxy-L-proline(in) + H(+)(in) <=> 4-hydroxy-L-proline(out) + H(+)(out)


name: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP <=> 8-desmethylnovobiocic acid + AMP + diphosphate


name: 5-nitroanthranilate + H(+) + H2O <=> 5-nitrosalicylate + NH4(+)


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Canis familiaris)


name: ethane-1-sulfonate + FMNH2 + O2 <=> acetaldehyde + FMN + 2 H(+) + H2O + sulfite


name: 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate = CO2 + 2 H2O + NAD(+) + proviolacein


name: 5-dehydroepisterol + 2 H2O + NADP(+) <=> ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2


name: (9Z,12Z)-octadecadienoyl-CoA + FAD + H(+) = (2E,9Z,12Z)-octadecatrienoyl-CoA + FADH2


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Sus scrofa)


name: UVSSA:USP7 deubiquitinates ERCC6 (Bos taurus)


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)


name: a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GP1calpha (d18:1(4E)) + CMP + H(+)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Gallus gallus)


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Mus musculus)


name: MBTPS1 (S1P) cleaves CREB3 (Gallus gallus)


name: PTPN11 dephosphorylates RUNX1 (Xenopus tropicalis)


name: a cytidine in tRNA + S-adenosyl-L-methionine <=> an N(3)-methylcytidine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 2 7-demethylsiderin + NADPH + O2 <=> 2 H2O + NADP(+) + orlandin


name: 2-AG hydrolysis to arachidonate by MAGL (Sus scrofa)


name: a 2-(omega-methylsulfanyl)alkylmaleate + H2O => a 2-(omega-methylsulfanyl)alkylmalate


name: Cdc6 protein is phosphorylated by CDK (Gallus gallus)


name: Formation of dehydro-lysinonorleucine cross-links (Caenorhabditis elegans)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Homo sapiens)


name: a polar amino acid(out) + ATP + H2O => a polar amino acid(in) + ADP + H(+) + phosphate


name: ATP + CoA + succinate = ADP + phosphate + succinyl-CoA


name: Necl-1:Nectin 3 trans heterodimer interaction (Gallus gallus)


name: (5Z,8Z)-octadecadienoate + O2 <=> (5S)-hydroperoxy-(6E,8Z)-octadecadienoate


name: 1-O-alkylglycerone 3-phosphate + H(+) + NADPH = 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Homo sapiens)


name: [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + H2O <=> [CysO sulfur-carrier protein]-C-terminal Gly-Gly + H(+) + L-cysteine


name: CDT1-mediated loading of MCM2-7 to replication origins (Homo sapiens)


name: ATP + sedoheptulose = ADP + D-sedoheptulose 7-phosphate + H(+)


name: UDP-alpha-D-glucuronate + wogonin = UDP + wogonin 7-O-beta-D-glucuronate


name: NGF binding to p75NTR inactivates RHOA (Mus musculus)


name: 2-hydroxyethylphosphonate + O2 <=> H(+) + hydrogencarbonate + methylphosphonate


name: acetyl-CoA + decanedioyl-CoA => 3-oxododecanedioyl-CoA + CoA


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Homo sapiens)


name: a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP-alpha-D-galactose <=> a neolactoside IV(3)-beta-[Gal-beta-(1->3)-GlcNAc]-nLc4Cer(d18:1(4E)) + H(+) + UDP


name: 3 H(+) + 3 malonyl-CoA + N-methylanthraniloyl-CoA <=> 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O


name: 4-amino-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 4-amino-5-hydroxy-3-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Trimerization of the FASL:FAS receptor complex (Gallus gallus)


name: beta-nicotinamide D-riboside(in) = beta-nicotinamide D-riboside(out)


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Rattus norvegicus)


name: RDH12 reduces atRAL to atROL (Sus scrofa)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Rattus norvegicus)


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Schizosaccharomyces pombe)


name: dTDP-3-dehydro-6-deoxy-alpha-D-glucose + L-glutamate => 2-oxoglutarate + dTDP-3-amino-3,6-dideoxy-alpha-D-glucose


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Mus musculus)


name: H2O + methylguanidine <=> methylamine + urea


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Plasmodium falciparum)


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Mus musculus)


name: acetylglucosamine is transferred from UDP-GlcNAc onto inositol-1-phosphate (Mycobacterium tuberculosis)


name: (R)-2-methylpyrrolidine + NADP(+) = 2-methyl-1-pyrroline + H(+) + NADPH


name: Aquaporins passively transport glycerol out of cells (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O => a 2'-deoxyribonucleoside + H(+) + triphosphate


name: 3-oxocholan-24-oyl-CoA + NAD(+) <=> 3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + CoA + H(+) => 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Bos taurus)


name: AMP(in) + UMP(out) => AMP(out) + UMP(in)


name: CALM1:Ca2+ binds CNG channel (Homo sapiens)


name: SGMS2 transfers phosphocholine onto ceramide (Xenopus tropicalis)


name: O2 + putrescine <=> 1-pyrroline + H2O2 + NH4(+)


name: dammarenediol-II = (S)-2,3-epoxysqualene + H2O


name: NR3C1 binds NR3C1 agonists (Canis familiaris)


name: DHCR24 reduces LAN to 24,25-dhLAN (Xenopus tropicalis)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] <=> 6beta-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Bos taurus)


name: 4,21-dehydrogeissoschizine + NADPH => (19E)-geissoschizine + NADP(+)


name: PC is hydrolyzed to 2-acyl LPC by PLA2G4C (Homo sapiens)


name: USP11 deubiquitinates NFKBIA (Homo sapiens)


name: 2-oxoglutarate + O2 + preaustinoid A2 => CO2 + H2O + preaustinoid A3 + succinate


name: (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate => (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O


name: 5'-deoxyadenosine + H2O = 5-deoxy-D-ribose + adenine


name: RAC3 translocates to the endoplasmic reticulum membrane (Gallus gallus)


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Canis familiaris)


name: PKC autophosphorylates (Schizosaccharomyces pombe)


name: SLC25A10 mediates exchange of malate and phosphate (Drosophila melanogaster)


name: MAPK6 binds CCND3 (Schizosaccharomyces pombe)


name: Caspase-mediated cleavage of Desmoglein 3 (Rattus norvegicus)


name: PDE4A,C,D hydrolyse cAMP (Rattus norvegicus)


name: Furin cleaves pro-protein C to protein C (Rattus norvegicus)


name: ATP + N-acetyl-D-muramate <=> ADP + H(+) + N-acetyl-alpha-D-muramate 1-phosphate


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RGGT geranylgeranylates RAB proteins (Plasmodium falciparum)


name: ERCC5 and RPA bind TC-NER site (Gallus gallus)


name: Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Mus musculus)


name: (S)-2-amino-6-oxohexanoate <=> H(+) + H2O + L-1-piperideine-6-carboxylate


name: (3R)-hydroxyeicosanoyl-CoA + NAD(+) = 3-oxoeicosanoyl-CoA + H(+) + NADH


name: H2O + NAD(+) + phosphonate <=> H(+) + NADH + phosphate


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: 3-hydroxybutane-1,2,3-tricarboxylate <=> 2-methyl-cis-aconitate + H2O


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Dictyostelium discoideum)


name: KCTD6 gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Mus musculus)


name: NOTCH precursor cleaved to form mature NOTCH (Homo sapiens)


name: 2-nitroimidazole + H2O => 1,3-dihydro-2H-imidazol-2-one + H(+) + nitrite


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-O-hexadecyl-sn-glycero-3-phosphocholine + H(+)


name: (R)-lactate + N-acetyl-D-glucosamine 6-phosphate => H2O + N-acetyl-D-muramate 6-phosphate


name: Dissociation of the TP:Gq complex (Canis familiaris)


name: dihydrorhizobitoxine + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + rhizobitoxine


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: Formation of the Flap Intermediate on the C-strand (Sus scrofa)


name: Interaction of PAK1 with Rac1-GTP (Sus scrofa)


name: (S)-2-amino-6-oxohexanoate + H(+) + NADPH + NH4(+) => H2O + L-lysine + NADP(+)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Xenopus tropicalis)


name: G protein-coupled glycine receptor activity


name: Transport of fringe-modified NOTCH to plasma membrane (Gallus gallus)


name: 2 H(+) + hexadecanoate + NADH = H2O + hexadecanal + NAD(+)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Sus scrofa)


name: N-acetyl-D-glucosamine + O2 => H2O2 + N-acetyl-D-glucosamino-1,5-lactone


name: SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Xenopus tropicalis)


name: L-mimosine <=> 2-aminoprop-2-enoate + 3-hydroxy-4H-pyrid-4-one


name: double-stranded DNA endonuclease activity


name: folate(out) + H(+)(out) => folate(in) + H(+)(in)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Homo sapiens)


name: CYP39A1 7-hydroxylates 24OH-CHOL (Mus musculus)


name: PPO oxidises PPGEN9 to PRIN9 (Bos taurus)


name: Binding of EGF to ligand-responsive EGFR mutants (Homo sapiens)


name: p75NTR interacts with RIP2 (Mus musculus)


name: (E)-caffeoyl-CoA + 5-hydroxyanthranilate => avenanthramide C + CoA


name: (R,R)-butane-2,3-diol + NAD(+) => (R)-acetoin + H(+) + NADH


name: Arachidonic acid is oxidised to 12S-HpETE by ALOX12/15 (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: H2O2 + tetradecanoate = (3R)-hydroxytetradecanoate + H2O


name: BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Saccharomyces cerevisiae)


name: Rheb in the MTORC1 complex hydrolyses GTP (Mus musculus)


name: Beta-defensins bind microbial membranes causing disruption (Mus musculus)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Rattus norvegicus)


name: Co(I)-[trimethylamine-specific corrinoid protein] + H(+) + trimethylamine => dimethylamine + methyl-Co(III)-[trimethylamine-specific corrinoid protein]


name: (2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-[protein] <=> 2'-deoxyribonucleotide-DNA + H(+) + S-methyl-L-cysteinyl-[protein]


name: 2-chloro-4-nitrotoluene + NADH + O2 => 3-chloro-4-methylcatechol + NAD(+) + nitrite


name: (E)-2,3-didehydroadipoyl-CoA + H2O => (3S)-3-hydroxyadipyl-CoA


name: H(+)(in) + L-phenylalanyl-L-phenylalanine(in) => H(+)(out) + L-phenylalanyl-L-phenylalanine(out)


name: holo-[(hydroxy)phthioceranic acid synthase] + octadecanoyl-AMP = AMP + H(+) + octadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Rattus norvegicus)


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Sus scrofa)


name: (-)-medicarpin + H2O => (3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol


name: Activated FGFR4 binds SHC1 (Gallus gallus)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)


name: a long-chain fatty acid + ATP + H(+) = a long-chain fatty acyl-AMP + diphosphate


name: DOLK phosphorylates DCHOL to DOLP (Mus musculus)


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Homo sapiens)


name: MET dimers autophosphorylate (Caenorhabditis elegans)


name: dihydroferuloyl-CoA + NADP(+) = (E)-feruloyl-CoA + H(+) + NADPH


name: Myeloperoxidase (MPO) binds to the bacterial cell surface (Caenorhabditis elegans)


name: Degradation of multiubiquitinated Nek2A (Xenopus tropicalis)


name: ATP + cob(I)alamin-[corrinoid adenosyltransferase] = adenosylcob(III)alamin + apo-[corrinoid adenosyltransferase] + triphosphate


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Bos taurus)


name: Dissociation of the Gi alpha:G olf complex (Caenorhabditis elegans)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Mus musculus)


name: L-cysteine + S-sulfanyl-L-cysteine => L-alanine + S-disulfanyl-L-cysteine


name: MIA2 binds PREB (Drosophila melanogaster)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Rattus norvegicus)


name: XIAP dissociates from ub-TLE (Homo sapiens)


name: MRM1 methylates guanosine-1145 of 16S rRNA yielding 2'-O-methylguanosine-1145 (Homo sapiens)


name: Assembly of EGFR complex in clathrin-coated vesicles (Caenorhabditis elegans)


name: oxoglutarate dehydrogenase (NAD+) activity


name: ATP + D-galactose(out) + H2O <=> ADP + D-galactose(in) + H(+) + phosphate


name: Initial activation of proMMP7 by trypsin (Xenopus tropicalis)


name: Dopamine synaptic vesicle docking and priming (Rattus norvegicus)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Plasmodium falciparum)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Xenopus tropicalis)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Rattus norvegicus)


name: Beclin-1 complex translocates to the ER (Caenorhabditis elegans)


name: H2O + meso-2,6-diaminoheptanedioate + NADP(+) <=> (S)-2-amino-6-oxoheptanedioate + H(+) + NADPH + NH4(+)


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: COQ5 methylates MDMQ10H2 (Schizosaccharomyces pombe)


name: Interaction of GPVI and FceRI gamma (Bos taurus)


name: RHOJ binds effectors at the plasma membrane (Homo sapiens)


name: GP1b-IX-V binds filamin (Rattus norvegicus)


name: SMURF2 ubiquitinates SMAD2 (Xenopus tropicalis)


name: Expression of NANOG in primordial germ cells (Homo sapiens)


name: H(+) + iso-precytochalasin + NADPH + O2 => cytochalasin Z16 + H2O + NADP(+)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Sus scrofa)


name: 4-(trimethylamino)butanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => crotonobetainyl-CoA + reduced [electron-transfer flavoprotein]


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-ethanolamine <=> 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: TFAM binds to mitochondrial promoters (Gallus gallus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (3E,7E)-dolabella-3,7-dien-18-ol + diphosphate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O => (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-glycerol + H(+)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: HGFAC cleaves pro-HGF to form HGF dimer (Canis familiaris)


name: a triacyl-sn-glycerol + H2O = a 1,2-diacylglycerol + a fatty acid + H(+)


name: (2S,4R)-ketoconazole(in) + ATP + H2O = (2S,4R)-ketoconazole(out) + ADP + H(+) + phosphate


name: alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate => alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Schizosaccharomyces pombe)


name: ATP + CoA + sulfoacetate <=> AMP + diphosphate + sulfoacetyl-CoA


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Caenorhabditis elegans)


name: TRiC/CCT binds unfolded G-protein beta subunit (Xenopus tropicalis)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: A + a 3-oxo-Delta(4)-steroid => a 3-oxo-Delta(1,4)-steroid + AH2


name: Phosphorylation of SLP-76 (Canis familiaris)


name: VRK1/VRK2 phosphorylate BANF1 (Sus scrofa)


name: ATP + streptomycin => ADP + H(+) + streptomycin 6-phosphate


name: (22R)-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (20R,22R)-20,22-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol => (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Sus scrofa)


name: diphosphate + pentalenene => (2E,6E)-farnesyl diphosphate


name: D-kanosamine 6-phosphate + H2O => kanosamine + phosphate


name: "heme oxygenase (biliverdin-IX-beta and delta-forming)"


name: 2-oxobutanoate + H(+) + pyruvate => (S)-2-ethyl-2-hydroxy-3-oxobutanoate + CO2


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Danio rerio)


name: beta-D-glucose 6-phosphate => beta-D-glucose 1-phosphate


name: PIAS1 SUMOylates THRB with SUMO3 (Sus scrofa)


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Xenopus tropicalis)


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Mus musculus)


name: H2O + thiosulfinate => 2 (E)-prop-1-en-1-SO-peroxol


name: ethanolamine + H2O + O2 <=> glycolaldehyde + H2O2 + NH4(+)


name: RUNX2 binds ZNF521 and HDAC3 (Homo sapiens)


name: SPAM1 Binds Hyaluronic Acid (Homo sapiens)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Danio rerio)


name: H(+)(in) + L-leucyl-L-leucine(in) => H(+)(out) + L-leucyl-L-leucine(out)


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-acetyl-4'-phosphopantetheine => acetyl-CoA + H2O


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Bos taurus)


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex (Homo sapiens)


name: Na(+)(in) + pyruvate(in) => Na(+)(out) + pyruvate(out)


name: FMNL2 binds CDC42:GTP (Caenorhabditis elegans)


name: CBL ubiquitinates FRS2 and FGFR1 (Drosophila melanogaster)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Bos taurus)


name: precorrin-2 + S-adenosyl-L-methionine => H(+) + precorrin-3A + S-adenosyl-L-homocysteine


name: H2O + N-phenylhydroxylamine + 2 NADP(+) = 2 H(+) + 2 NADPH + nitrobenzene


name: CBL-mediated ubiquitination of CIN85 (Bos taurus)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: Translocation of Cdc25 to the nucleus (Gallus gallus)


name: ANO2:Ca2+ translocates Cl- from the cytosol to the extracellular region (Homo sapiens)


name: Basigin binds MCT1, MCT3 and MCT4 (Bos taurus)


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)


name: DMRT1 binds the FOXL2 gene (Homo sapiens)


name: Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD domain mutants (Homo sapiens)


name: glutarate(in) + succinate(out) = glutarate(out) + succinate(in)


name: PKA phosphorylates RET:GDNF:GFRA dimer (Mus musculus)


name: FLAD1 phosphorylates FMN (Dictyostelium discoideum)


name: 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O <=> (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: LGI1 binds ADAM22 and ADAM23 (Mus musculus)


name: a beta-D-glucuronoside + alpha-D-glucose 1-phosphate => a 3-O-beta-D-glucosyl-beta-D-glucuronoside + phosphate


name: Hh-Np traffics to the plasma membrane (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Xenopus tropicalis)


name: bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose => 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+)


name: Cytosolic DUSPs dephosphorylate MAPKs (Plasmodium falciparum)


name: 2-AG hydrolysis to arachidonate by MAGL (Plasmodium falciparum)


name: hexacosanoyl-CoA + O2 => trans-2,3-dehydrohexacosanoyl-CoA + H2O2 (Mus musculus)


name: TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains  (Gallus gallus)


name: 2 AMP + didemethylasterriquinone D + 2 diphosphate + H(+) => 2 ATP + 2 indole-3-pyruvate


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Rattus norvegicus)


name: Phosphorylation (Ser5) of RNA pol II CTD (Xenopus tropicalis)


name: MICAL1 produces NADP+, H2O2 (Danio rerio)


name: GDP-alpha-D-mannose + H2O <=> alpha-D-mannose 1-phosphate + GMP + 2 H(+)


name: p-STAT5 dissociates from mutant FLT3 (Homo sapiens)


name: AcK-NFE2L2 binds the ABCC3 gene (Homo sapiens)


name: BCDIN3D dimethylates 5' phosphate of pre-miR-145 (Homo sapiens)


name: CHSY1 transfers GalNAc to chondroitin (Danio rerio)


name: aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Sus scrofa)


name: NH4(+) + oxaloacetate => (3S)-3-hydroxy-L-aspartate


name: C37-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+) => 2 (S)-methylmalonyl-CoA + 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Danio rerio)


name: 2-oxoglutarate + chloride + H(+) + hapalindole U + O2 <=> CO2 + H2O + hapalindole G + succinate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O


name: H2O + hexylamine + NAD(+) => H(+) + hexanal + NADH + NH4(+)


name: H2O + S-hexadecanoyl-L-cysteinyl-[protein] => H(+) + hexadecanoate + L-cysteinyl-[protein]


name: Heterodimerization of CEACAMs (Sus scrofa)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ADA deamidates RBV (Plasmodium falciparum)


name: GLUT7 and GLUT11 transport glucose and fructose (Canis familiaris)


name: 3-oxo-(13Z)-eicosenoyl-CoA + H(+) + NADPH => (R)-3-hydroxy-(13Z)-eicosenoyl-CoA + NADP(+)


name: [(2->1)-beta-D-fructosyl](n) + sucrose => [(2->1)-beta-D-fructosyl](n+1) + D-glucose


name: campesterol + O2 + reduced [NADPH--hemoprotein reductase] => (22S)-22-hydroxycampesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Necl-1:Nectin 3 trans heterodimer interaction (Canis familiaris)


name: (9Z,12Z)-octadecadienoate(out) + ATP(in) + CoA(in) + H(+)(out) => (9Z,12Z)-octadecadienoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + octanoyl-CoA => 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA


name: a 2-acylphloroglucinol + dimethylallyl diphosphate <=> a 2-acyl-4-prenylphloroglucinol + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(+) + UDP


name: RHAG transports CO2 from extracellular region to cytosol (Danio rerio)


name: 6-acetamido-2-oxohexanoate + H2O + NAD(+) = 5-acetamidopentanoate + CO2 + H(+) + NADH


name: eicosanoyl-CoA + sphinganine = CoA + H(+) + N-eicosanoylsphinganine


name: 2 3-hexadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol) => 3-hexadecanoyl-sn-glycero-1-phospho-(3'-hexadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)


name: (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O => (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate


name: 3,17-didehydrostemmadenine + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-dehydro-L-idonate + NADP(+) => 2,5-didehydro-D-gluconate + H(+) + NADPH


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => a monoacyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: 5-hydroxy-L-arginine <=> guanidine + L-glutamate 5-semialdehyde


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Sus scrofa)


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Danio rerio)


name: S1P hydrolyzes SREBP1A,1C,2 (Mus musculus)


name: Activated FGFR1:p-FRS bind to PPTN11 (Sus scrofa)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Xenopus tropicalis)


name: DKK promotes clathrin-dependent internalization of LRP6 (Rattus norvegicus)


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Sus scrofa)


name: Polyadenylation of SARS-CoV-2 subgenomic mRNAs (plus strand) (Homo sapiens)


name: P-type potassium transmembrane transporter activity


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+) => a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphate + H2O


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + [thioredoxin]-dithiol => [thioredoxin]-disulfide + adenosine 3',5'-bisphosphate + 2 H(+) + sulfite


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Canis familiaris)


name: Exocytosis of secretory granule lumen proteins (Bos taurus)


name: Phosphorylation of APS (Canis familiaris)


name: GDIs block activation of RHOA (Xenopus tropicalis)


name: 2',4,4',6'-tetrahydroxychalcone + dimethylallyl diphosphate <=> desmethylxanthohumol + diphosphate


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Xenopus tropicalis)


name: Adenylate cyclase converts ATP into cyclic AMP (Bos taurus)


name: 6'''-deamino-6'''-hydroxyneomycin C + O2 = 6'''-deamino-6'''-oxoneomycin C + H2O2


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (13R)-hydroxy-(9Z,11E)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Dictyostelium discoideum)


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Sus scrofa)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Sus scrofa)


name: a dolichyl phosphate + UDP-alpha-D-glucose = a dolichyl beta-D-glucosyl phosphate + UDP


name: H(+)(out) + L-alanyl-L-glutamate(out) <=> H(+)(in) + L-alanyl-L-glutamate(in)


name: L-cysteine + L-histidine + O2 => H2O + L-alanin-3-yl L-histidin-5-yl sulfoxide


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Gallus gallus)


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Rattus norvegicus)


name: PTGS2 dimer oxidises EPA to PGH3 (Bos taurus)


name: CYP2E1 monooxygenates APAP to NAPQI (Dictyostelium discoideum)


name: (E)-caffeoyl-CoA + H2O <=> 3-hydroxy-3-(3,4-dihydroxyphenyl)propanoyl-CoA


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Bos taurus)


name: RAC2 binds effectors at the plasma membrane (Gallus gallus)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Sus scrofa)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Homo sapiens)


name: RUNX2:CBFB binds the MMP13 gene promoter (Homo sapiens)


name: RNA Polymerase II Promoter Opening: First Transition (Bos taurus)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Drosophila melanogaster)


name: ADP + beta-D-galactose(in) + H(+) + phosphate => ATP + beta-D-galactose(out) + H2O


name: H2O + N(5)-[1(S)-1-carboxyethyl]-L-ornithine + NADP(+) => H(+) + L-ornithine + NADPH + pyruvate


name: CCNG1 recruits PP2A-PPP2R5C to MDM2 (Rattus norvegicus)


name: 11beta-prostaglandin F2-ethanolamide + NADP(+) => H(+) + NADPH + prostaglandin D2-ethanolamide


name: (2E)-butenoyl-[ACP] + H(+) + NADPH <=> butanoyl-[ACP] + NADP(+)


name: ATP + L-pyrrolysine + tRNA(Pyl) <=> AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl)


name: inositol 2-dehydrogenase (NAD+) activity


name: SYVN1 ubiquitinates Hh C-terminal fragments (Bos taurus)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Canis familiaris)


name: kaempferol + UDP-beta-L-rhamnose => H(+) + kaempferol 3-O-alpha-L-rhamnoside + UDP


name: (Z)-2-methylureidoacrylate + H2O => (Z)-2-methylaminoacrylate + carbamate + H(+)


name: acetyl-CoA + N-terminal glycyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetylglycyl-[protein]


name: Activated FGFR1 phosphorylates SHC1 (Drosophila melanogaster)


name: CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Mus musculus)


name: 4-methylumbelliferone sulfate(in) + ATP + H2O => 4-methylumbelliferone sulfate(out) + ADP + H(+) + phosphate


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Homo sapiens)


name: H2O + O-phospho-L-tyrosyl-[protein] => L-tyrosyl-[protein] + phosphate


name: UDP-alpha-D-galactose(in) + UDP-N-acetyl-alpha-D-galactosamine(out) = UDP-alpha-D-galactose(out) + UDP-N-acetyl-alpha-D-galactosamine(in)


name: Translocation of PDGF from ER to Golgi (Danio rerio)


name: Cleavage of p-STK3 (p-MST2) by caspase 3 (Danio rerio)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Xenopus tropicalis)


name: folate(in) + H(+)(in) <=> folate(out) + H(+)(out)


name: TRAF3 binds TICAM1:activated TLR4 complex (Canis familiaris)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Caenorhabditis elegans)


name: acetyl-CoA + N-terminal L-alanyl-[ribosomal protein uS5] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein uS5]


name: "[ribosomal protein uS5]-alanine N-acetyltransferase"


name: 2,6,10,14-tetramethylpentadecanal + H2O + NAD(+) <=> 2,6,10,14-tetramethylpentadecanoate + 2 H(+) + NADH


name: Cytosolic DUSPs dephosphorylate MAPKs (Homo sapiens)


name: Activated MAPKs phosphorylate BRAF (Gallus gallus)


name: 3-ethylcatechol + H(+) + NADH => cis-1,2-dihydro-3-ethylcatechol + NAD(+)


name: an alkylmercury + H(+) = an alkane + Hg(2+)


name: gibberellin A3 + S-adenosyl-L-methionine <=> O-methyl gibberellin A3 + S-adenosyl-L-homocysteine


name: a dolichyl D-xylosyl phosphate + L-seryl-[protein] <=> 3-O-(beta-D-xylosyl)-L-seryl-[protein] + a dolichyl phosphate + H(+)


name: ATP + D-xylose(out) + H2O <=> ADP + D-xylose(in) + H(+) + phosphate


name: dAMP(in) + phosphate(out) => dAMP(out) + phosphate(in)


name: Formation of the CTF18 complex (Mus musculus)


name: PKA catalytic subunit translocates to the nucleus (Homo sapiens)


name: Binding of CBL to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)


name: Activation of conventional Protein Kinase C (Danio rerio)


name: Autocatalytic phosphorylation of FGFR1b (Mus musculus)


name: (R)-lipoyl-GMP + diphosphate => (R)-lipoate + GTP + H(+)


name: Activation of proMMP9 by proteases (Gallus gallus)


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Mus musculus)


name: H2O + L-serine-phosphoethanolamine <=> H(+) + L-serine + phosphoethanolamine


name: ervincine + H(+) + S-adenosyl-L-homocysteine => picrinine + S-adenosyl-L-methionine


name: Indirect recruitment of GAB2 to p-KIT (Bos taurus)


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Canis familiaris)


name: ent-copalyl diphosphate synthase activity


name: The Kiss receptor GPR54 binds kisspeptin (Bos taurus)


name: Dissociation of CANX from nonameric complex (Mus musculus)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Bos taurus)


name: tetrapeptide transmembrane transporter activity


name: M6PR transports activated ARSA to the lysosome (Sus scrofa)


name: a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate <=> 3-hydroxypropyl isothiocyanate + sulfate


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Bos taurus)


name: Galanin receptors can bind galanin (Homo sapiens)


name: HLA-B specific inhibitory MHC class I receptor activity


name: trans-3-hydroxy-L-proline <=> 1-pyrroline-2-carboxylate + H2O


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Homo sapiens)


name: H(+)(out) + L-cystine(out) = H(+)(in) + L-cystine(in)


name: ent-isokauren-2beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => ent-isokaurene + O2 + reduced [NADPH--hemoprotein reductase]


name: TGFBR3 binding to FGF2 (Rattus norvegicus)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Homo sapiens)


name: corticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 18-hydroxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: ATP + spectinomycin = 9-O-adenylylspectinomycin + diphosphate


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + O-phospho-L-seryl-[protein] <=> 1D-myo-inositol hexakisphosphate + O-diphospho-L-seryl-[protein]


name: DHI and DHICA polymerize forming eumelanin (Rattus norvegicus)


name: PLC gamma 2-mediated PIP2 hydrolysis (Sus scrofa)


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Xenopus tropicalis)


name: 2-exo-hydroxy-1,8-cineole + NAD(+) <=> 6-oxocineole + H(+) + NADH


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Saccharomyces cerevisiae)


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Drosophila melanogaster)


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)


name: a glycerophospholipid + H2O => a 2-acyl-sn-glycero-3-phospholipid + a fatty acid + H(+)


name: p-S133-CREB1 binds MIR132 gene promoter (Homo sapiens)


name: Latent TGF-beta-1 binds integrins (Mus musculus)


name: a monosubstituted aliphatic (S)-hydroxynitrile = an aldehyde + hydrogen cyanide


name: NAD(+) + scyllo-inosose => 3-dehydro-scyllo-inosose + H(+) + NADH


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Rattus norvegicus)


name: PKR binds activating host RNA (Rattus norvegicus)


name: [(1->4)-6-phospho-alpha-D-glucosyl](n) + n AMP + 2n H(+) + n phosphate => [(1->4)-alpha-D-glucosyl](n) + n ATP + n H2O


name: 3-oxo-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA + NADP(+)


name: chlorophyllide a + NADP(+) => H(+) + NADPH + protochlorophyllide a


name: 2-oxoglutarate(out) + L-2-aminoadipate(in) <=> 2-oxoglutarate(in) + L-2-aminoadipate(out)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Dictyostelium discoideum)


name: H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide => a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine


name: BESTs transport cytosolic HCO3- to extracellular region (Gallus gallus)


name: Ubiquitinated TP53 translocates to the cytosol (Rattus norvegicus)


name: phosphorylated HSL + H2O -> HSL + orthophosphate (Homo sapiens)


name: n chloride(in) + urate(out) => n chloride(out) + urate(in)


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Gallus gallus)


name: methylmalonyl-CoA + N(6)-biotinyl-L-lysyl-[protein] => N(6)-carboxybiotinyl-L-lysyl-[protein] + propanoyl-CoA


name: RAS GAP mutants aren't stimulated by GAPs (Homo sapiens)


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Mus musculus)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Sus scrofa)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Xenopus tropicalis)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Plasmodium falciparum)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Dictyostelium discoideum)


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Xenopus tropicalis)


name: H2O + N-benzoylglycine => benzoate + glycine


name: 3-deoxyglucosone + L-lysyl-[protein] + phosphate => H2O + N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein]


name: (6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate


name: a 3beta-hydroxysteroid + a triacylglycerol = a 1,3-diacylglycerol + a 3beta-hydroxysteroid ester


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Canis familiaris)


name: CASP3 cleaves GSDME (Xenopus tropicalis)


name: Formation of CSL-NICD coactivator complex (Sus scrofa)


name: dihydroferuloyl-CoA + NADP(+) <=> (E)-feruloyl-CoA + H(+) + NADPH


name: N,N',N''-triacetylchitotriose + O2 => H2O2 + N,N',N''-triacetylchitotriono-1,5-lactone


name: Addition of GlcNAc to the glycan on the A arm (Dictyostelium discoideum)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Danio rerio)


name: Transport of L1 into endosomes (Schizosaccharomyces pombe)


name: ATP + geranoyl-CoA + hydrogencarbonate <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + H(+) + phosphate


name: enterobactin + UDP-alpha-D-glucose => monoglucosyl-enterobactin + UDP


name: (3R)-hydroxybutanoate tetramer + H2O = (3R)-hydroxybutanoate trimer + (R)-3-hydroxybutanoate + H(+)


name: GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA (Homo sapiens)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine


name: TLR4-induced ripoptosome assembly (Gallus gallus)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Caenorhabditis elegans)


name: Type B histone acetlytransferase complex acetylates histone H4 (Schizosaccharomyces pombe)


name: 1,2,3-tripropanoylglycerol + H2O = dipropanoylglycerol + H(+) + propanoate


name: GABA loaded synaptic vesicle Docking and Priming (Xenopus tropicalis)


name: IRAK4 is activated by autophosphorylation (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + dodecanoyl-CoA => 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + CoA


name: UBQLNs bind UIM-containing adaptor proteins (Drosophila melanogaster)


name: Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Homo sapiens)


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Mus musculus)


name: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Danio rerio)


name: cis-homoaconitate + H2O => (2R)-homocitrate


name: (S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-cheilanthifoline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: methyl (-)-jasmonate + S-adenosyl-L-homocysteine => jasmonate + S-adenosyl-L-methionine


name: Canonical WNT signaling through the atypical receptor RYK (Mus musculus)


name: Activated protein C binds Protein S (Bos taurus)


name: CO2 + gibberellin A9 + 4 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] => gibberellin A12 + 5 H(+) + 3 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(+) + NADH => 12alpha-hydroxy-3-oxochola-4-en-24-oate + NAD(+)


name: histone H2AK13 ubiquitin ligase activity


name: β-blockers bind ADRB1,2,3 (Homo sapiens)


name: USP44 deubiquitinates CDC20 (Rattus norvegicus)


name: L-histidine(in) + L-phenylalanine(out) <=> L-histidine(out) + L-phenylalanine(in)


name: ROS oxidize thioredoxin (Saccharomyces cerevisiae)


name: 2 Fe(III)-[cytochrome c] + L-ascorbate => 2 Fe(II)-[cytochrome c] + 2 H(+) + L-dehydroascorbate


name: (2R,3Z)-phycocyanobilin + 4 oxidized [2Fe-2S]-[ferredoxin] <=> biliverdin IXalpha + 4 H(+) + 4 reduced [2Fe-2S]-[ferredoxin]


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O = ADP-alpha-D-ribose 1''-phosphate + H(+)


name: Interaction of integrin alphaVbeta3 with Tenascin (Bos taurus)


name: Active MTORC1 binds the ULK1 complex (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+)


name: 9alpha-hydroxy-3-oxochola-1,4-dien-22-oyl-CoA + H2O + NAD(+) => 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH + O2


name: 4-acetamidobutanoate + H2O <=> 4-aminobutanoate + acetate


name: an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose = a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+)


name: butanoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (2E)-butenoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: "butanoyl-CoA dehydrogenase complex (NAD(+), ferredoxin)"


name: a fatty acyl-[ACP] + S-adenosyl-L-methionine <=> an N-acyl-L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-thioadenosine


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Mus musculus)


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Xenopus tropicalis)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Bos taurus)


name: Binding of Grb10 to the insulin receptor (Bos taurus)


name: 3,4-dihydroxybenzoate + H2O + NADP(+) => 3-hydroxybenzoate + H(+) + NADPH + O2


name: (2S,3S)-2-methylcitrate + CoA + H(+) => H2O + oxaloacetate + propanoyl-CoA


name: 3-methylpentanoate + ATP + CoA <=> 3-methylpentanoyl-CoA + AMP + diphosphate


name: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) => 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH


name: 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Homo sapiens)


name: H2O + orobanchol = 5-hydroxy-3-methylfuran-2(5H)-one + orobanchol ABC-rings


name: UBQLNs bind UIM-containing adaptor proteins (Bos taurus)


name: coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity


name: Addition of nucleotides 10 and 11 on the growing HIV-1 transcript: Third Transition (Homo sapiens)


name: type 2 proteinase activated receptor binding


name: 6-aminopenicillanate + a carboxylate => a penicillin + H2O


name: protein arginine N5-methyltransferase activity


name: MAPK1 phosphorylates SOX10 (Rattus norvegicus)


name: 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: 3'-phosphoadenylyl sulfate + a phenolic steroid = a phenolic steroid 3-O-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: ATP + streptomycin => ADP + H(+) + streptomycin 3''-phosphate


name: Protein kinase C, alpha type phosphorylates MARCKS (Sus scrofa)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 1-O-(1,2-saturated-alkyl)-sn-glycerol + O2 => (6R)-L-erythro-6,7-dihydrobiopterin + a 1-(1-hydroxyalkyl)-sn-glycerol + H2O


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Drosophila melanogaster)


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Rattus norvegicus)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Rattus norvegicus)


name: CoA + H(+) + N(2)-malonyl-D-tryptophan => D-tryptophan + malonyl-CoA


name: growth hormone-releasing hormone receptor activity


name: (E)-4-coumaraldehyde + CoA + NADP(+) <=> (E)-4-coumaroyl-CoA + H(+) + NADPH


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + H(+) + hexadecanoate


name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Sus scrofa)


name: TGFBR2 does not recruit TGFBR1 LBD Mutants (Homo sapiens)


name: PGH2 is degraded to 12S-HHT and MDA by TBXAS1 (Mus musculus)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Danio rerio)


name: ATP + D-maltose <=> ADP + alpha-maltose 1-phosphate + H(+)


name: 5-dehydro-D-gluconate + H(+) + NADH => D-gluconate + NAD(+)


name: HMG CoA => acetoacetic acid + acetyl CoA (Drosophila melanogaster)


name: p-PKR dimer phosphorylates CDK1 (Bos taurus)


name: PAK binds RAC and bPIX (Rattus norvegicus)


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = an anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] + CoA + H(+)


name: (2S)-3-sulfopropanediol => 3-oxopropane-1-sulfonate + H2O


name: ub-GLI is degraded by the proteasome (Homo sapiens)


name: Caveolin-1 binds Basigin (Caenorhabditis elegans)


name: Expression of SRPR (SRP Receptor subunit alpha) (Homo sapiens)


name: (2E)-octacosenoyl-CoA + H(+) + NADPH => NADP(+) + octacosanoyl-CoA


name: N-hydroxy-L-tetrahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-tetrahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine => guanosine(26) in tRNA + 2 S-adenosyl-L-methionine


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Canis familiaris)


name: ATP + H2O + selenite(out) <=> ADP + H(+) + phosphate + selenite(in)


name: RAC3 GDIs block activation of RAC3 (Sus scrofa)


name: beta-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + ursodeoxycholate


name: (4R)-hydroxyeicosasphinganine + a fatty acyl-CoA = CoA + H(+) + N-acyl-4-hydroxyeicosasphinganine


name: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde


name: acetyl-CoA + docosanoyl-CoA <=> 3-oxotetracosanoyl-CoA + CoA


name: 2 Na(+)(in) + tetrahydroxoborate(in) <=> 2 Na(+)(out) + tetrahydroxoborate(out)


name: (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O => (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + L-glutamate


name: (3S)-hydroxydecanedioyl-CoA + NAD(+) => 3-oxodecanedioyl-CoA + H(+) + NADH


name: ITP + pyruvate = H(+) + IDP + phosphoenolpyruvate


name: NOTCH1 t(7;9)(NOTCH1:M1580_K2555) is cleaved to produce NEXT1 (Homo sapiens)


name: 2-carboxy-5-(dihydroxymethyl)furan => 2-carboxy-5-formylfuran + H2O


name: PLC beta-mediated PIP2 hydrolysis (Sus scrofa)


name: 5-hydroxyquinolin-2(1H)-one + AH2 => A + H2O + quinolin-5-ol


name: Dimethyl fumarate modifies Cys191 in GSDMD (Gallus gallus)


name: (2S)-2-phospholactate + GTP + H(+) => (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate


name: ATP + D-sedoheptulose 7-phosphate = ADP + D-sedoheptulose 1,7-bisphosphate + H(+)


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer at the origin (Canis familiaris)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (Caenorhabditis elegans)


name: NFE2L2 binds KEAP1:NEDD8-CUL3:RBX1 (Homo sapiens)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Rattus norvegicus)


name: PP1 dephosphorylates phosphorylated TIM (Drosophila melanogaster)


name: (R)-carnitine + 2,6-dimethylheptanoyl-CoA <=> CoA + O-2,6-dimethylheptanoyl-(R)-carnitine


name: Hikeshi binds HSP70s:ATP (Dictyostelium discoideum)


name: cholesterol + NADP(+) = 7-dehydrocholesterol + H(+) + NADPH


name: Collagen type III degradation by MMP15 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + phosphate


name: GSTO dimers reduce DeHA to AscH- (Mus musculus)


name: KPNA2 translocates NBN to the nucleus (Danio rerio)


name: inositol diphosphate tetrakisphosphate diphosphatase activity


name: 3-oxotetradecanedioyl-CoA + H(+) + NADH => (3S)-hydroxytetradecanedioyl-CoA + NAD(+)


name: deoxycholate + ursodeoxycholoyl-CoA => deoxycholoyl-CoA + ursodeoxycholate


name: H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Drosophila melanogaster)


name: (9Z)-octadecenoate + H(+) + holo-[ACP] => (9Z)-octadecenoyl-[ACP] + H2O


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Homo sapiens)


name: Oxytocin receptor bind oxytocin (Sus scrofa)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Canis familiaris)


name: (4R)-hydroxysphinganine + tetracosanoyl-CoA = CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphinganine


name: Cleavage of C3 by C3 convertases (Bos taurus)


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + 8-methyladenosine(2503) in 23S rRNA + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Sus scrofa)


name: Heterotrimeric G(s) complex dissociates (Homo sapiens)


name: Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine (Homo sapiens)


name: Beta-catenin recruits TRRAP/KAT5 HAT components (Homo sapiens)


name: 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine => adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine


name: B4GALT1:LALBA transfers Gal from UDP-Gal to Glc to form Lac (Canis familiaris)


name: phosphate + validoxylamine A => H2O + validoxylamine A 7'-phosphate


name: Mcm2-7 is phosphorylated by DDK (Rattus norvegicus)


name: a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+) => a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O


name: CLN3 transports GalCer to plasma membrane (Canis familiaris)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Mus musculus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate


name: GATA4, GATA6, and ISL1:LDB1 bind the HAND2 gene (Homo sapiens)


name: RNF5 and RNF185 ubiquitinate CFTR F508del (Homo sapiens)


name: 1-nitrocyclohexan + NADP(+) => 1-nitrocyclohexene + H(+) + NADPH


name: cytidine(1409) in 16S rRNA + S-adenosyl-L-methionine => 2'-O-methylcytidine(1409) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 7(1)-hydroxychlorophyllide a + NAD(+) <=> chlorophyllide b + H(+) + NADH


name: Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)


name: PRMT5 is tyrosine phosphorylated by JAK2 V617F (Homo sapiens)


name: eIF3 and eIF1A bind to the 40S subunit (Xenopus tropicalis)


name: 1-(ergostan-3beta-yl)-L-aspartate + H2O = ergosterol + H(+) + L-aspartate


name: D-allo-threonine + H2O + O2 => (R)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+)


name: HLCS biotinylates ACACA:Mn2+ (Dictyostelium discoideum)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Danio rerio)


name: avenanthramide A + CoA => (E)-4-coumaroyl-CoA + 5-hydroxyanthranilate


name: BTN3A1 and BTN1A1 binds periplakin (PPL) (Canis familiaris)


name: Interaction of Tie2 and Shp2 (Canis familiaris)


name: SUMOylation of UBE2I with SUMO1 (Caenorhabditis elegans)


name: Receptor CCR10 binds CCL27 and 28 ligands (Sus scrofa)


name: Calcium binds calmodulin at the synapse (Homo sapiens)


name: PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Canis familiaris)


name: 5-hydroxymethyl-dUMP in DNA + ATP => 5-phosphomethyl-dUMP in DNA + ADP + H(+)


name: GSDME (1-270) binds cardiolipin (Danio rerio)


name: FOXO3 binds BTG1 gene promoter (Homo sapiens)


name: Cleavage of uracil by TDG glycosylase (Rattus norvegicus)


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Sus scrofa)


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate


name: 2-methylcyclopentanone + H(+) + NADPH + NH4(+) => 2-methylcyclopentanamine + H2O + NADP(+)


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O => dTDP-alpha-D-glucose


name: Recruitment of VAV and BTK to p-SLP-76 (Mus musculus)


name: Binding of TFIIIA To type 1 Promoter (Gallus gallus)


name: malonyl-CoA + S-adenosyl-L-methionine = malonyl-CoA methyl ester + S-adenosyl-L-homocysteine


name: acetyl-[citrate lyase ACP] + H2O <=> acetate + H(+) + holo-[citrate lyase ACP]


name: Expression of EEPD1 regulated by NR1H2 or NR1H3 (Homo sapiens)


name: Cargo-carrying vesicles bud from the TGN (Xenopus tropicalis)


name: SHP2 phosphatase binds CTLA-4 (Gallus gallus)


name: 6-amino-2-oxohexanoate + H2O2 = 5-aminopentanoate + CO2 + H2O


name: H2O + neryl diphosphate <=> diphosphate + nerol


name: Dopamine is oxidised to noradrenaline (Drosophila melanogaster)


name: EFCAB7:IQCE binds EVC2:EVC (Homo sapiens)


name: (9Z)-octadecenoate + O2 => (2R,9Z)-2-hydroperoxyoctadecenoate


name: ESRRA:PPARG1CA binds the RUNX2 gene promoter (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Bos taurus)


name: Tyrosine kinase Hopscotch (HOP) binds to the transmembrane cytokine receptor Domeless (DOME) to form the HOP:DOME complex (Drosophila melanogaster)


name: SALL4 recruits NuRD to PTEN gene (Drosophila melanogaster)


name: G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) (Gallus gallus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Mus musculus)


name: Phosphorylation of IFNGR1 by JAK kinases (Rattus norvegicus)


name: Dissociation of p-Y427-SHC1 from insulin receptor (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O = (9Z)-octadecenoate + 1-hexadecanoyl-3-octadecanoyl-sn-glycerol + H(+)


name: H2O + N-(15Z-tetracosenoyl)-taurine => (15Z)-tetracosenoate + taurine


name: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH => 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+)


name: hexanoate + sphinganine => H2O + N-hexanoyl-sphinganine


name: Interaction of E3 with substrate and E2-Ub complex (Canis familiaris)


name: H2O + hexano-6-lactone + NADP(+) => cyclohexanone + H(+) + NADPH + O2


name: ATP + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine = 6-O-phospho-N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine + ADP + H(+)


name: a carboxylate + an L-alpha-amino acid => an N-acyl-L-amino acid + H2O


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Saccharomyces cerevisiae)


name: H2O + N(7)-methyl-GMP = N(7)-methylguanosine + phosphate


name: H(+) + N-acyl-15-methylhexadecasphinganine + NADPH + O2 <=> H2O + N-acyl-4-hydroxy-15-methylhexadecasphinganine + NADP(+)


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Gallus gallus)


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Canis familiaris)


name: (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: ATP(in) + CoA(in) + H(+)(out) + octanoate(out) <=> AMP(in) + diphosphate(in) + H(+)(in) + octanoyl-CoA(in)


name: N-acetyl-L-aspartate(in) + 3 Na(+)(in) => N-acetyl-L-aspartate(out) + 3 Na(+)(out)


name: COQ2 ligates all-E-10PrP2 to PHB (Homo sapiens)


name: The FA anion diffuses away laterally from UCP (Xenopus tropicalis)


name: PIP2 hydrolysis (Schizosaccharomyces pombe)


name: chloride + FADH2 + O2 + tetracycline = 7-chlorotetracycline + FAD + H(+) + 2 H2O


name: DERA cleaves dR5P to GA3P and CH3CHO (Mus musculus)


name: cAMP dissociates PKA, promoting GLI processing (Danio rerio)


name: D-glucose + NADP(+) => D-glucono-1,5-lactone + H(+) + NADPH


name: L-gulonate + NAD(+) => H(+) + keto-D-fructuronate + NADH


name: GP1b-IX-V:13-3-3-zeta complexes with p85 PI3K (Sus scrofa)


name: 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+) => an inositol-1-phosphoceramide + H2O


name: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP => 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate = diphosphate + sobralene


name: p-Y420-FYN is phosphorylated on S21 (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine <=> 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phospho-L-serine


name: PTK2beta binds alphaVbeta3 (Gallus gallus)


name: Activation of THIK (Caenorhabditis elegans)


name: 3-oxopropanoate + CoA + NADP(+) = acetyl-CoA + CO2 + NADPH


name: Nephrin interacts with Podocin (Bos taurus)


name: (cis-prenyl)(n+1)-diphosphate + diphosphate => (cis-prenyl)n-diphosphate + isopentenyl diphosphate


name: CO2 + dialkyl ketone + L-alanine => 2,2-dialkylglycine + H(+) + pyruvate


name: CHIT1 hydrolyses CHIT to 3xADGP (Rattus norvegicus)


name: 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA => (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + H(+) + malonyl-CoA


name: a pseudouridine in tRNA => a uridine in tRNA


name: CHEK1 phosphorylates E2F6 (Mus musculus)


name: dGTP + methylglyoxal <=> N(2)-(1-hydroxy-2-oxopropyl)-dGTP


name: SHP1 (PTPN6) binds JAK2 in the receptor complex (Homo sapiens)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: D-cellohexaose + O2 => D-cellohexaono-1,5-lactone + H2O2


name: Release of L-Glutamate at the synapse (Homo sapiens)


name: L-glutamate + N(2)-acetyl-L-ornithine <=> L-ornithine + N-acetyl-L-glutamate


name: digoxin + 2 Fe(II)-[cytochrome c] + 3 H(+) = dihydrodigoxin + 2 Fe(III)-[cytochrome c]


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)


name: SOS mediated nucleotide exchange of RAS (SHC) (Homo sapiens)


name: Calmodulin dissociates KRAS4B from the plasma membrane (Gallus gallus)


name: Phosphorylated HOP is dephosphorylated by PTP61F isoform 1 (Drosophila melanogaster)


name: L-alanine(out) + L-valine(in) => L-alanine(in) + L-valine(out)


name: CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 (Homo sapiens)


name: ATP + glutathione(out) + H2O => ADP + glutathione(in) + H(+) + phosphate


name: Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Bos taurus)


name: Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (Rattus norvegicus)


name: PXLP-K405-GAD1 decarboxylates L-Glu to form GABA (Mus musculus)


name: Ca impermeable AMPA receptor ligand binding (Mus musculus)


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Drosophila melanogaster)


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 => (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: acetyl-CoA + 2 H(+) + 2 malonyl-CoA = 2 CO2 + 3 CoA + triacetate lactone


name: acetyl phosphate + phosphate => acetate + diphosphate


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Rattus norvegicus)


name: (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 = (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2


name: H(+) + O-phospho-L-serine + phosphate => diphosphate + L-serine


name: 2'-deoxyinosine + phosphate => dIMP + H2O


name: Co(2+) + precorrin-2 => Co-precorrin-2 + 3 H(+)


name: (2S)-2-hydroxyhexanenitrile => hydrogen cyanide + pentanal


name: chlorophyllide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = 7(1)-hydroxychlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Danio rerio)


name: Release of 40S and 60S subunits from the 80S ribosome  (Saccharomyces cerevisiae)


name: a dolichyl beta-D-mannosyl phosphate + GDP => a dolichyl phosphate + GDP-alpha-D-mannose


name: ATP translocates from cytosol to extracellular space (stimuated by C3AR1:C3a) (Homo sapiens)


name: ATP + carbamate <=> ADP + carbamoyl phosphate


name: Matrix metalloproteinase proteolyzes IGF:IGFBP3:ALS (Danio rerio)


name: ULK1 is dephosphorylated (Saccharomyces cerevisiae)


name: PIP3 binds to RhoA and activates it (Schizosaccharomyces pombe)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: H2O + O2 + spermidine <=> 3-aminopropanal + H2O2 + putrescine


name: (9Z)-hexadecen-1-ol + (9Z)-octadecenoyl-CoA <=> 1-O-(9Z)-hexadecenyl (9Z)-octadecenoate + CoA


name: PARVB interacts with Alpha-actinin (Gallus gallus)


name: 3-oxochenodeoxycholate + H(+) + NADH <=> isochenodeoxycholate + NAD(+)


name: KLRC1:KLRD1 heterodimer interacts with HLA-E (Gallus gallus)


name: D-xylulose 1,5-bisphosphate + H2O => D-xylulose 5-phosphate + phosphate


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> (R)-nephthenol + diphosphate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Gallus gallus)


name: ERK1/2 phosphorylates MSK1 (Caenorhabditis elegans)


name: Translocation of CARMA1 to Plasma membrane (Mus musculus)


name: a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+)


name: NOTCH1 stimulates MYC transcription (Homo sapiens)


name: ATP + CoA + oxalate => AMP + diphosphate + oxalyl-CoA


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Gallus gallus)


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Canis familiaris)


name: 2-oxoglutarate + O2 + validoxylamine A => CO2 + H(+) + succinate + validoxylamine B


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Gallus gallus)


name: 5-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: ERK1/2/5 activate RSK1/2/3 (Gallus gallus)


name: SESN1,2 binds L-leucine and dissociates from GATOR2 (Rattus norvegicus)


name: DENND1s exchange GTP for GDP on RAB35 (Rattus norvegicus)


name: Mitochondrial recruitment of Drp1 (Saccharomyces cerevisiae)


name: IRS1 recruits GRB2 to active LTK (Homo sapiens)


name: Caspase-mediated cleavage of alpha adducin (Canis familiaris)


name: 1-(10Z-heptadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine


name: GBA1:SAPC hydrolyzes GlcCer (Rattus norvegicus)


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Bos taurus)


name: L-cysteinyl-[protein] + S-nitroso-CoA = CoA + S-nitroso-L-cysteinyl-[protein]


name: benzoate + H(+) + NADH + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: discoidol + O2 + reduced [NADPH--hemoprotein reductase] => acetone + discodiene + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (6Z,9Z,12Z)-octadecatrienoate + H2O => (10S)-hydroxy-(6Z,12Z)-octadecadienoate


name: ATP + H2O + L-alanyl-L-histidine(out) => ADP + H(+) + L-alanyl-L-histidine(in) + phosphate


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Rattus norvegicus)


name: ATP + isopropylamine + L-glutamate => ADP + gamma-L-glutamyl-isopropylamide + H(+) + phosphate


name: H(+) + N(3)-methyluridine(2634) in 25S rRNA + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(2634) in 25S rRNA


name: cAMP degradation by Phosphodiesterases (Caenorhabditis elegans)


name: HCFC1, HCFC2 bind the MLL1:MEN1 complex (Drosophila melanogaster)


name: NCOA3 recruits EP300 to ESR1:estrogen:TFGA gene:NCOA3 (Sus scrofa)


name: H2O + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] = L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] + phosphate


name: RHOT1 hydrolyzes GTP (Saccharomyces cerevisiae)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)


name: NADP(+) + sn-glycerol 3-phosphate = D-glyceraldehyde 3-phosphate + H(+) + NADPH


name: GTP + L-lysyl-[protein] = diphosphate + H(+) + N(epsilon)-GMP-L-lysyl-[protein]


name: GPR35 binds kynurenic acid (Xenopus tropicalis)


name: AH2 + ATP + ilicicolinate B = A + AMP + diphosphate + ilicicolin B


name: ABHD10 hydrolyses MPAG (Rattus norvegicus)


name: [DsrC protein]-disulfide + H(+) + hydrogen sulfide <=> [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Xenopus tropicalis)


name: Caspase-mediated cleavage of Tau (Canis familiaris)


name: Formation of the Spliceosomal P complex and exon ligation (Danio rerio)


name: NAMPT transfers PRIB to NAM to form NAMN (Sus scrofa)


name: eIF3 and eIF1A bind to the 40S subunit (Dictyostelium discoideum)


name: RHOT2 binds effectors at the mitochondrial outer membrane (Schizosaccharomyces pombe)


name: GTP loading by Rheb (Schizosaccharomyces pombe)


name: glycodeoxycholate + H2O <=> deoxycholate + glycine


name: 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + H(+) + NADH => choloyl-CoA + NAD(+)


name: H2O + N-terminal L-arginyl-L-amino acid-[protein] = an N-terminal L-alpha-aminoacyl-[protein] + L-arginine


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Caenorhabditis elegans)


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Sus scrofa)


name: epothilone B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => epothilone D + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2-(acetamidomethylene)succinate + H(+) + 2 H2O <=> acetate + CO2 + NH4(+) + succinate semialdehyde


name: EGFRvIII mutant binds chaperone proteins HSP90 and CDC37. (Homo sapiens)


name: Constitutive phosphorylation by GSK3 (Mus musculus)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Homo sapiens)


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Mus musculus)


name: 4-[(2-hydroxyethoxy)carbonyl]benzoate + H2O => ethylene glycol + H(+) + terephthalate


name: Association of Cyclin A with the APC/C (Mus musculus)


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Homo sapiens)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Caenorhabditis elegans)


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Bos taurus)


name: GNLY is transferred to the phagosome (Danio rerio)


name: discoidol + O2 + reduced [NADPH--hemoprotein reductase] = acetone + discodiene + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + m-xylene + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3-methylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H(+) + NADPH + S-nitroso-CoA <=> NADP(+) + sulfinamide-CoA


name: 4-sulfomuconolactone + H2O => 2 H(+) + maleylacetate + sulfite


name: (7S)-marmesin + O2 + reduced [NADPH--hemoprotein reductase] <=> acetone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + psoralen


name: MET phosphorylates SHC1-2 (Mus musculus)


name: USP1:WDR48 binds monoUb:K164-PCNA (Rattus norvegicus)


name: Phosphorylation of PLC-gamma1 (Bos taurus)


name: Interleukin-1 family precursors are cleaved by caspase-1 (Bos taurus)


name: acetyl-CoA + N-terminal L-methionyl-L-leucyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-leucyl-[protein]


name: Phosphorylation of YAP by LATS2 (Canis familiaris)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Xenopus tropicalis)


name: hydrolase activity, hydrolyzing N-glycosyl compounds


name: MAT1A multimers transfer Ado from ATP to L-Met (Plasmodium falciparum)


name: H(+)(out) + 2 nitrate(out) = H(+)(in) + 2 nitrate(in)


name: ADK phosphorylates RBV (Rattus norvegicus)


name: 5-amino-6-(D-ribitylamino)uracil + glyoxal <=> 5-(2-oxoethylideneamino)-6-(D-ribitylamino)uracil + H2O


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Translocation of PTK2 to Focal complexes (Gallus gallus)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Rattus norvegicus)


name: GNLY binds the bacterial cell surface (Homo sapiens)


name: Passive I- efflux mediated by SLC5A8 (Canis familiaris)


name: Release of E3 from polyubiquitinated substrate (Danio rerio)


name: gamma-secretase cleaves EPHB2 (Bos taurus)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Sus scrofa)


name: E2F8 forms homodimers (Canis familiaris)


name: 3-oxocholestane + A + H2O <=> 25-hydroxy 3-oxocholestane + AH2


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)


name: (9Z,12Z,15Z)-octadecatrien-1-ol + 1-hexadecanoylglycerone 3-phosphate <=> 1-O-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate + H(+) + hexadecanoate


name: all-trans-4-oxoretinol + NAD(+) <=> all-trans-4-oxoretinal + H(+) + NADH


name: 3 3-oxopropanoate + 3 H(+) + H2O2 + 2 nitrate + nitrite => H2O + 3 O2 + 3 propionate 3-nitronate


name: Formation of tonofilament bundles (Gallus gallus)


name: H(+) + NADP(+) + 2 superoxide => NADPH + 2 O2


name: ATP + S-disulfanyl-L-cysteine + tRNA(Cys) => (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate


name: beta-nicotinamide D-ribonucleotide + H2O = NH4(+) + nicotinate beta-D-ribonucleotide


name: Regeneration of eEF1A:GTP by eEF1B activity (Sus scrofa)


name: PTHP is reduced to BH4 by sepiapterin reductase (SPR) (Sus scrofa)


name: beta-D-gentiobiosyl beta-D-glucosyl crocetin + H(+) + UDP => bis(beta-D-glucosyl) crocetin + UDP-alpha-D-glucose


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> diphosphate + pseudolaratriene


name: TTLLs polyglutamylate tubulin (Canis familiaris)


name: activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)


name: Nephrin interacts with Podocin (Mus musculus)


name: glutathione(in) + leukotriene C4(out) => glutathione(out) + leukotriene C4(in)


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Xenopus tropicalis)


name: (S)-reticuline + O2 => (S)-scoulerine + H(+) + H2O2


name: 2-oxoglutarate + N(6)-methyladenosine in U6 snRNA + O2 => adenosine in U6 snRNA + CO2 + formaldehyde + succinate


name: (3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) => [(3R)-hydroxybutanoate](n+1) + CoA


name: RFC dissociates after sliding clamp formation on the C-strand of the telomere (Sus scrofa)


name: (3R)-3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O


name: Loading of PCNA - Sliding Clamp Formation (Mus musculus)


name: 2-oxoglutarate(out) + glutarate(in) = 2-oxoglutarate(in) + glutarate(out)


name: NLRC5 binds IKBKB and CHUK (Homo sapiens)


name: 17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP => 17beta-estradiol + UDP-alpha-D-glucuronate


name: Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation<br> (Drosophila melanogaster)


name: H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-galactosamine


name: Interaction of DAP12 and KIR2DS5 (Mus musculus)


name: Active FLT3:GRB2 binds SOS1 (Sus scrofa)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Schizosaccharomyces pombe)


name: L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs (Homo sapiens)


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Bos taurus)


name: AH2 + trichloroethene <=> (Z)-1,2-dichloroethene + A + chloride + H(+)


name: chorismate + NH4(+) => (2S)-2-amino-4-deoxychorismate + H2O


name: FLT3 mutants phosphorylate GAB2 (Homo sapiens)


name: 1-phenylpropylamine + pyruvate <=> 1-phenylpropan-1-one + L-alanine


name: Interaction of DAP12 and TREM2 (Mus musculus)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Drosophila melanogaster)


name: D-arabinose + NADP(+) = D-arabinono-1,5-lactone + H(+) + NADPH


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + a carboxylate + H(+)


name: PIAS4 SUMOylates TOP2A with SUMO2,3 (Drosophila melanogaster)


name: (+)-valencene + diphosphate => (2E,6E)-farnesyl diphosphate


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Danio rerio)


name: RFC binding displaces Pol Alpha (Plasmodium falciparum)


name: BCDX2 complex stabilizes RAD51 filament (Rattus norvegicus)


name: Autoglucosylation of GYG1 complexed with GYS1-b (Homo sapiens)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Schizosaccharomyces pombe)


name: beta-D-Man-(1->4)-alpha-L-Rha-(1->3)-alpha-D-Gal-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+) => alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP-alpha-D-mannose


name: TBC1D10A (EPI64) binds ARF6:GTP (Bos taurus)


name: decan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] = 1,7-decanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Hydrolysis of ATP and release of folded actin from CCT/TriC (Homo sapiens)


name: Activated TRAF6 synthesizes free K63 linked pUb chains. (Gallus gallus)


name: docosanoate + glycine => H2O + N-docosanoylglycine


name: CS acetylates OA to citrate (Caenorhabditis elegans)


name: 5'-deoxyadenosine + H(+) + H2O <=> 5'-deoxyinosine + NH4(+)


name: PRTPRF, PTPRS, PTPRD bind LRRC4B (Canis familiaris)


name: FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: H(+) + nonanoyl-CoA + oxidized [electron-transfer flavoprotein] => (2E)-nonenoyl-CoA + reduced [electron-transfer flavoprotein]


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Dictyostelium discoideum)


name: glycyl-L-aspartate(out) + 2 H(+)(out) <=> glycyl-L-aspartate(in) + 2 H(+)(in)


name: Activation of MMP9 intermediate form by MMPs (Caenorhabditis elegans)


name: AMP + diphosphate + pseudomonoyl-CoA C => ATP + CoA + pseudomonate C


name: Activation of RAC1 by the PXN:CRK complex (Rattus norvegicus)


name: CO2 + formate + methylamine + succinate semialdehyde => (E)-2-((N-methylformamido) methylene)succinate + H(+) + 2 H2O


name: SEC4C,D bind GOSR2 and STX5 (Bos taurus)


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Rattus norvegicus)


name: coenzyme M + methyl-Co(III)-[trimethylamine-specific corrinoid protein] <=> Co(I)-[trimethylamine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine = 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester


name: aurachin C + H(+) + NADPH + O2 = aurachin C epoxide + H2O + NADP(+)


name: Activated human JNKs migrate to nucleoplasm (Canis familiaris)


name: SMAD2/3:SMAD4 heterotrimer forms a complex with RBL1, E2F4/5 and DP1/2 (Rattus norvegicus)


name: RCHY1 monoubiquitinates POLH (Mus musculus)


name: 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Homo sapiens)


name: Translocation of peptide bound MHC class I complex to cell surface (Sus scrofa)


name: mitomycin A + S-adenosyl-L-homocysteine => 6-demethylmitomycin A + S-adenosyl-L-methionine


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Xenopus tropicalis)


name: ATP + O-(5'-adenylyl)-L-tyrosyl-[protein] = diphosphate + O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein]


name: STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Sus scrofa)


name: The retrograde IFT train dissociates (Sus scrofa)


name: HCMV Genome Replication Completion (Homo sapiens)


name: lipoxin A4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-lipoxin A4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: delta-tocotrienol + S-adenosyl-L-methionine = beta-tocotrienol + H(+) + S-adenosyl-L-homocysteine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Homo sapiens)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Saccharomyces cerevisiae)


name: WWTR1 binds SMAD2/3:SMAD4 heterotrimer (Rattus norvegicus)


name: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1) => beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3)


name: RNA polymerase II general transcription initiation factor binding


name: 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Rattus norvegicus)


name: butan-2-ol + NAD(+) <=> butan-2-one + H(+) + NADH


name: Collagen type XVIII endostatin release (Mus musculus)


name: 4-nitrophenol + H(+) + NADH + O2 = 4-nitrocatechol + H2O + NAD(+)


name: 2-methylpropanoyl-CoA + H(+) + malonyl-[ACP] <=> 4-methyl-3-oxopentanoyl-[ACP] + CO2 + CoA


name: GDP + H(+) + methyl 8-{[beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate => GDP-beta-L-fucose + methyl 8-{[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosamyl]oxy}nonanoate


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Plasmodium falciparum)


name: adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H2O = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + H(+) + phosphate


name: CDK4 inhibitors bind CDK4 (Drosophila melanogaster)


name: LARG activation by G alpha 12/13 (Caenorhabditis elegans)


name: 3-oxooctadecanoyl-CoA + H(+) + NADH => 3-hydroxyoctadecanoyl-CoA + NAD(+)


name: A + decanedioyl-CoA = (2E)-decenedioyl-CoA + AH2


name: PIAS4 SUMOylates IKBKG with SUMO1 (Bos taurus)


name: P2X1-mediated entry of Ca++ from plasma (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate + L-tryptophyl-[protein] = (2S,3R)-3-farnesyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate


name: a diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base => a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Dictyostelium discoideum)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Saccharomyces cerevisiae)


name: Ethylene is oxidized to Ethylene oxide by CYP1A1 (Mus musculus)


name: a cytidine(6-4)cytidine in DNA <=> a cytidine dimer in DNA + H(+)


name: H2O + N,N'-diacetylchitobiose = acetate + N-acetyl-beta-D-glucosaminyl-(1->4)-D-glucosamine


name: (1R,4R)-5-oxo-1,2-campholide => [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)


name: 9-(acyloxy)-octadecanoate + a 2,3-diacyl-sn-glycerol => 9-hydroxy-octadecanoate + a triacylglycerol


name: acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA


name: (6Z)-octadecenamide + H2O => (6Z)-octadecenoate + NH4(+)


name: (3S)-3,6-diaminohexanoate + acetyl-CoA = (3S)-6-acetamido-3-aminohexanoate + CoA + H(+)


name: MTMR4 dephosphorylates SMAD2/3 (Canis familiaris)


name: N(2)-(1-hydroxy-2-oxoethyl)-GTP => glyoxal + GTP


name: 7(1)-hydroxychlorophyll a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => chlorophyll a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: hexadecanoyl-CoA + sphinganine => CoA + H(+) + N-hexadecanoylsphinganine


name: cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) (Mus musculus)


name: (E)-4-hydroxynon-2-enal + H2O + O2 <=> (E)-4-hydroxynon-2-enoate + H(+) + H2O2


name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Schizosaccharomyces pombe)


name: Multiubiquitination of Nek2A (Bos taurus)


name: 2 AH2 + all-trans-beta-carotene + 2 O2 => 2 A + echinenone + 3 H2O


name: a globoside Gb4Cer + UDP-N-acetyl-alpha-D-galactosamine = a globoside IV3GalNAc-Gb4Cer + H(+) + UDP


name: 2,3-dihydroxy-3-methylbutanoate <=> 3-methyl-2-oxobutanoate + H2O


name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex (Bos taurus)


name: XIAP monoubiquinates TLE (Canis familiaris)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Homo sapiens)


name: I(1,3,4)P3 is dephosphorylated to I(3,4)P2 by INPP1 in the cytosol (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphate


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Caenorhabditis elegans)


name: Co-precorrin-5A + H2O = acetaldehyde + Co-precorrin-5B + H(+)


name: DSCAM/DSCAML1 homodimerization (Canis familiaris)


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Rattus norvegicus)


name: VD3 dissociates from GC (Canis familiaris)


name: a very long-chain fatty acid + ATP + CoA = a very long-chain fatty acyl-CoA + AMP + diphosphate


name: formyl-CoA + succinate <=> formate + succinyl-CoA


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Gallus gallus)


name: TXN2 binds CysS248-MPST (Xenopus tropicalis)


name: cAMP dissociates PKA, promoting GLI processing (Gallus gallus)


name: 2-oxoglutarate + gibberellin A12 + O2 => CO2 + gibberellin A15 + succinate


name: Transport of MHC heterotrimer to ER exit site (Homo sapiens)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Drosophila melanogaster)


name: (R)-2-hydroxypropyl-coenzyme M <=> (R)-1,2-epoxypropane + coenzyme M


name: acetyl-CoA + L-threonyl-[protein] <=> CoA + O-acetyl-L-threonyl-[protein]


name: Autophosphorylation of PKC-theta (Bos taurus)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Sus scrofa)


name: a 5-methyluridine in 12S rRNA + H(+) + S-adenosyl-L-homocysteine => a uridine in 12S rRNA + S-adenosyl-L-methionine


name: petunidin + UDP-alpha-D-galactose <=> petunidin 3-O-beta-D-galactoside + UDP