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It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. 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These unmyelinated axons were first described by Ramon y Cajal."], "t": []}], "preferred_name": "hippocampal mossy fiber", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1621655", "l": "mating-type region heterochromatin", "d": [], "t": []}], "preferred_name": "mating-type region heterochromatin", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2323913", "l": "Set of cytoplasmic organelles of lens cell", "d": [], "t": []}], "preferred_name": "Set of cytoplasmic organelles of lens cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230904", "l": "Basal or external lamina of non-epithelial cell or tissue", "d": [], "t": []}, {"i": "SNOMEDCT:88113007", "d": [], "t": []}], "preferred_name": "Basal or external lamina of non-epithelial cell or tissue", "taxa": []} {"type": "biolink:CellularComponent", "ic": "58.901549449650162", "identifiers": [{"i": "GO:0140513", "l": "nuclear protein-containing complex", "d": ["A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus."], "t": []}], "preferred_name": "nuclear protein-containing complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:1902500", "l": "vacuolar HOPS complex", "d": ["Any HOPS complex that is part of a vacuolar membrane."], "t": []}], "preferred_name": "vacuolar HOPS complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990085", "l": "Hda-beta clamp complex", "d": ["A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda."], "t": []}], "preferred_name": "Hda-beta clamp complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179988", "l": "Zone of tail of spermatozoon", "d": [], "t": []}], "preferred_name": "Zone of tail of spermatozoon", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2610567", "l": "yolk plasma", "d": [], "t": []}], "preferred_name": "yolk plasma", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "UMLS:C1521233", "l": "2q36.3", "d": [], "t": []}, {"i": "NCIT:C25042", "l": "2q36.3", "d": ["A chromosome band present on 2q"], "t": []}], "preferred_name": "2q36.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1819017", "l": "dense core granule membrane", "d": [], "t": []}], "preferred_name": "dense core granule membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2611197", "l": "Mad-Max-mSin3B complex", "d": [], "t": []}], "preferred_name": "Mad-Max-mSin3B complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167024", "l": "food vacuole", "d": [], "t": []}], "preferred_name": "food vacuole", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896408", "l": "ANPR-A receptor complex", "d": [], "t": []}], "preferred_name": "ANPR-A receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2325569", "l": "Wall of endoplasmic reticulum tubule", "d": [], "t": []}], "preferred_name": "Wall of endoplasmic reticulum tubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4691111", "l": "pathogen inclusion membrane", "d": [], "t": []}], "preferred_name": "pathogen inclusion membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070369", "l": "beta-catenin-TCF7L2 complex", "d": ["A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription."], "t": []}], "preferred_name": "beta-catenin-TCF7L2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0062130", "l": "adhesive extracellular matrix", "d": ["A extracellular matrix which attaches an organism to a substrate."], "t": []}], "preferred_name": "adhesive extracellular matrix", "taxa": []} {"type": "biolink:CellularComponent", "ic": "79.629646129707766", "identifiers": [{"i": "GO:0070648", "l": "formin-nucleated actin cable", "d": ["An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth."], "t": []}], "preferred_name": "formin-nucleated actin cable", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179490", "l": "Cleft of Schmidt-Lanterman", "d": [], "t": []}], "preferred_name": "Cleft of Schmidt-Lanterman", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824224", "l": "DnaB6-DnaC3 complex", "d": [], "t": []}], "preferred_name": "DnaB6-DnaC3 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0071750", "l": "dimeric IgA immunoglobulin complex", "d": ["A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph."], "t": []}], "preferred_name": "dimeric IgA immunoglobulin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690296", "l": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex", "d": [], "t": []}], "preferred_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325555", "l": "Nuclear telomeric heterochromatin", "d": [], "t": []}], "preferred_name": "Nuclear telomeric heterochromatin", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097417", "l": "nematosome", "d": ["Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. 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The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase."], "t": []}], "preferred_name": "dystrophin-associated glycoprotein complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "NCIT:C13375", "l": "Chromosome Fragile Site", "d": ["Heritable sensitive regions of chromosomes which show up in vitro as non-staining bands. They are associated with chromosome breakage and other aberrations. No abnormal phenotype has been definitely identified with autosomal fragile sites, but some rare autosomal recessive disorders may be due to homozygosity for fragile sites. A fragile site on the X chromosome is associated with Fragile X Syndrome. Fragile sites are designated by the letters \"fra\" followed by the designation for the specific chromosome and locus."], "t": []}], "preferred_name": "Chromosome Fragile Site", "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.624156395578254", "identifiers": [{"i": "GO:0098845", "l": "postsynaptic endosome", "d": ["An endosomal compartment that is part of the post-synapse. 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The acroblast is situated adjacent to the acrosomal vesicle."], "t": []}], "preferred_name": "acroblast", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0010339", "l": "external side of cell wall", "d": ["The side of the cell wall that is opposite to the side that faces the cell and its contents."], "t": []}], "preferred_name": "external side of cell wall", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0012509", "l": "inter-Golgi transport vesicle membrane", "d": ["The lipid bilayer surrounding a vesicle transporting substances within the Golgi."], "t": []}], "preferred_name": "inter-Golgi transport vesicle membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044599", "l": "AP-5 adaptor complex", "d": ["An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo."], "t": []}], "preferred_name": "AP-5 adaptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "63.881908453739342", "identifiers": [{"i": "MESH:D021982", "l": "Cell-Matrix Junctions", "d": [], "t": []}, {"i": "UMLS:C0887869", "l": "Cell-Matrix Junction", "d": [], "t": []}, {"i": "NCIT:C20191", "l": "Cell-Matrix Adhesion Process", "d": ["Any cellular process in which a cell attaches to the extracellular matrix via adhesion molecules."], "t": []}], "preferred_name": "Cell-Matrix Junctions", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754278", "l": "alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex", "d": [], "t": []}], "preferred_name": "alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "59.842618009250089", "identifiers": [{"i": "GO:0043233", "l": "organelle lumen", "d": ["The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen."], "t": []}], "preferred_name": "organelle lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5450464", "l": "gamma-tubulin small complex, mitotic spindle pole body", "d": [], "t": []}], "preferred_name": "gamma-tubulin small complex, mitotic spindle pole body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070418", "l": "DNA-dependent protein kinase complex", "d": ["A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. 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The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. 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Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility."], "t": []}], "preferred_name": "S100A9 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156611", "l": "other organism presynaptic membrane", "d": [], "t": []}], "preferred_name": "other organism presynaptic membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1521415", "l": "4q32.2", "d": [], "t": []}, {"i": "NCIT:C13949", "l": "4q32.2", "d": ["A chromosome band present on 4q"], "t": []}], "preferred_name": "4q32.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4329169", "l": "axonemal nexin link", "d": [], "t": []}], "preferred_name": "axonemal nexin link", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0015050", "l": "methane monooxygenase complex", "d": ["A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized."], "t": []}], "preferred_name": "methane monooxygenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0106126", "l": "reservosome membrane", "d": ["The lipid bilayer surrounding a reservosome."], "t": []}], "preferred_name": "reservosome membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0474356", "l": "Myelinated retinal nerve fiber", "d": [], "t": []}], "preferred_name": "Myelinated retinal nerve fiber", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230658", "l": "Content of endocytic membrane invagination", "d": [], "t": []}, {"i": "SNOMEDCT:26395008", "d": [], "t": []}], "preferred_name": "Content of endocytic membrane invagination", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120234", "l": "stereocilium coat", "d": ["A glycocalyx on the the endolymphatic surface of a cochlear hair cell that coats the external surface of each stereocilium and maintains a small distance between adjacent stereocilia in the bundle."], "t": []}], "preferred_name": "stereocilium coat", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0045283", "l": "fumarate reductase complex", "d": ["A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone))."], "t": []}], "preferred_name": "fumarate reductase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120101", "l": "bacterial-type flagellum stator complex", "d": ["A hetero-hexameric complex of 2 membrane proteins, A and B, with stoichiometry A4B2. The A and B proteins form a channel through which flow the ions that power the bacterial-type flagellum. They form the stator, or nonrotating portion, of the flagellum motor with the B protein apparently attached to the peptidoglycan cell wall. Examples include the H+ driven MotA-MotB stator complex of Escherichia coli and Salmonella enterica, and the Na+ driven PomA-PomB stator complex of Vibrio and Shewanella species."], "t": []}], "preferred_name": "bacterial-type flagellum stator complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1337068", "l": "viral genome location", "d": [], "t": []}], "preferred_name": "viral genome location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821256", "l": "deuterosome", "d": [], "t": []}], "preferred_name": "deuterosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "86.296221842381144", "identifiers": [{"i": "UMLS:C1521186", "l": "2p23", "d": [], "t": []}, {"i": "NCIT:C13644", "l": "2p23", "d": ["A chromosome band present on 2p"], "t": []}], "preferred_name": "2p23", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097132", "l": "cyclin D2-CDK6 complex", "d": ["A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner."], "t": []}], "preferred_name": "cyclin D2-CDK6 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0036375", "l": "Kibra-Ex-Mer complex", "d": ["An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2."], "t": []}], "preferred_name": "Kibra-Ex-Mer complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "76.02785518950158", "identifiers": [{"i": "GO:0030880", "l": "RNA polymerase complex", "d": ["Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits."], "t": []}], "preferred_name": "RNA polymerase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1545526", "l": "Intercellular substance", "d": [], "t": []}], "preferred_name": "Intercellular substance", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1622729", "l": "thylakoid lumen", "d": [], "t": []}], "preferred_name": "thylakoid lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3154977", "l": "presynaptic dense body", "d": [], "t": []}], "preferred_name": "presynaptic dense body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521044", "l": "20p12", "d": [], "t": []}, {"i": "NCIT:C14008", "l": "20p12", "d": ["A chromosome band present on 20p"], "t": []}], "preferred_name": "20p12", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034692", "l": "E.F.G complex", "d": ["A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex."], "t": []}], "preferred_name": "E.F.G complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990901", "l": "old cell pole", "d": ["The cell pole distal from the most recent cell division."], "t": []}], "preferred_name": "old cell pole", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179917", "l": "Matrix of endosome", "d": [], "t": []}], "preferred_name": "Matrix of endosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754962", "l": "surface IgG2", "d": [], "t": []}], "preferred_name": "surface IgG2", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4235124", "l": "carbon phosphorus lyase complex", "d": [], "t": []}], "preferred_name": "carbon phosphorus lyase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005868", "l": "cytoplasmic dynein complex", "d": ["Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains."], "t": []}], "preferred_name": "cytoplasmic dynein complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2246608", "l": "DNA helicase complex", "d": [], "t": []}], "preferred_name": "DNA helicase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0043853", "l": "methanol-CoM methyltransferase complex", "d": ["A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol."], "t": []}], "preferred_name": "methanol-CoM methyltransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071118", "l": "alphaV-beta3 integrin-NOV complex", "d": ["A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV."], "t": []}], "preferred_name": "alphaV-beta3 integrin-NOV complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0140918", "l": "centrosomal core", "d": ["The core region of the centrosome, a layered structure containing proteins, surrounded by the centrosomal corona. The core duplicates once per cell cycle at the G2/M transition when two outer layers form the mitotic spindle poles."], "t": []}], "preferred_name": "centrosomal core", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230929", "l": "Flagellum, bacterial, shaft", "d": [], "t": []}, {"i": "SNOMEDCT:84964001", "d": [], "t": []}], "preferred_name": "Flagellum, bacterial, shaft", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0600317", "l": "Reticulopodia", "d": [], "t": []}], "preferred_name": "Reticulopodia", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523891", "l": "chloroplast ribosome", "d": [], "t": []}], "preferred_name": "chloroplast ribosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0042648", "l": "chloroplast chromosome", "d": ["A circular DNA molecule containing chloroplast encoded genes."], "t": []}], "preferred_name": "chloroplast chromosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0090577", "l": "RNA polymerase IV transcription regulator complex", "d": ["A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV."], "t": []}], "preferred_name": "RNA polymerase IV transcription regulator complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0016935", "l": "glycine-gated chloride channel complex", "d": ["A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts."], "t": []}], "preferred_name": "glycine-gated chloride channel complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990780", "l": "cytoplasmic side of dendritic spine plasma membrane", "d": ["The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine."], "t": []}], "preferred_name": "cytoplasmic side of dendritic spine plasma membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0048787", "l": "presynaptic active zone membrane", "d": ["The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters."], "t": []}], "preferred_name": "presynaptic active zone membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0000419", "l": "RNA polymerase V complex", "d": ["RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits."], "t": []}], "preferred_name": "RNA polymerase V complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3820520", "l": "extrinsic to cytoplasmic side of plasma membrane", "d": [], "t": []}], "preferred_name": "extrinsic to cytoplasmic side of plasma membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0333790", "l": "Viral nuclear inclusion body", "d": [], "t": []}, {"i": "SNOMEDCT:65482005", "d": [], "t": []}], "preferred_name": "Viral nuclear inclusion body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "GO:0009517", "l": "PSII associated light-harvesting complex II", "d": ["Protein-pigment complex associated with photosystem II."], "t": []}], "preferred_name": "PSII associated light-harvesting complex II", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523471", "l": "intraciliary transport particle A", "d": [], "t": []}], "preferred_name": "intraciliary transport particle A", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824228", "l": "DnaA-DNA complex", "d": [], "t": []}], "preferred_name": "DnaA-DNA complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754213", "l": "ITGA9-ITGB1-ADAM3 complex", "d": [], "t": []}], "preferred_name": "ITGA9-ITGB1-ADAM3 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821141", "l": "inversin compartment", "d": [], "t": []}], "preferred_name": "inversin compartment", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D000091582", "l": "Biomolecular Condensates", "d": [], "t": []}, {"i": "UMLS:C5544475", "l": "Biomolecular Condensates", "d": [], "t": []}], "preferred_name": "Biomolecular Condensates", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0140093", "l": "esBAF complex", "d": ["An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C."], "t": []}], "preferred_name": "esBAF complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166840", "l": "oligosaccharyltransferase complex", "d": [], "t": []}], "preferred_name": "oligosaccharyltransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4512550", "l": "Entire intercellular canaliculus", "d": [], "t": []}, {"i": "SNOMEDCT:727315007", "d": [], "t": []}], "preferred_name": "Entire intercellular canaliculus", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0042406", "l": "extrinsic component of endoplasmic reticulum membrane", "d": ["The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region."], "t": []}], "preferred_name": "extrinsic component of endoplasmic reticulum membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "68.340904352437406", "identifiers": [{"i": "MESH:D004721", "l": "Endoplasmic Reticulum", "d": [], "t": []}, {"i": "UMLS:C0014239", "l": "Endoplasmic Reticulum", "d": [], "t": []}, {"i": "NCIT:C13230", "l": "Endoplasmic Reticulum", "d": ["The endoplasmic reticulum is a network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials. (Infoplease Dictionary)"], "t": []}, {"i": "SNOMEDCT:33761008", "d": [], "t": []}], "preferred_name": "Endoplasmic Reticulum", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230634", "l": "Foot process of glomerular podocyte", "d": [], "t": []}, {"i": "SNOMEDCT:60302007", "d": [], "t": []}], "preferred_name": "Foot process of glomerular podocyte", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325558", "l": "Nuclear nucleosome", "d": [], "t": []}], "preferred_name": "Nuclear nucleosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "73.241175997074805", "identifiers": [{"i": "GO:0005840", "l": "ribosome", "d": ["An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins."], "t": []}], "preferred_name": "ribosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "72.001888423508461", "identifiers": [{"i": "GO:0031594", "l": "neuromuscular junction", "d": ["The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential."], "t": []}], "preferred_name": "neuromuscular junction", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3823076", "l": "glucosidase complex", "d": [], "t": []}], "preferred_name": "glucosidase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "58.537777560133563", "identifiers": [{"i": "GO:1990234", "l": "transferase complex", "d": ["A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor)."], "t": []}], "preferred_name": "transferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1819096", "l": "post-lysosomal vacuole", "d": [], "t": []}], "preferred_name": "post-lysosomal vacuole", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824555", "l": "BID-BCL-xl complex", "d": [], "t": []}], "preferred_name": "BID-BCL-xl complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2753841", "l": "gamma-secretase-Delta1 complex", "d": [], "t": []}], "preferred_name": "gamma-secretase-Delta1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1623087", "l": "extrinsic component of cell outer membrane", "d": [], "t": []}], "preferred_name": "extrinsic component of cell outer membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "GO:0045169", "l": "fusome", "d": ["A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. 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dehydrogenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2262709", "l": "periplasmic flagellum", "d": [], "t": []}], "preferred_name": "periplasmic flagellum", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821110", "l": "microvillar actin bundle", "d": [], "t": []}], "preferred_name": "microvillar actin bundle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230792", "l": "Agranular endoplasmic reticulum, connection with other organelle", "d": [], "t": []}, {"i": "SNOMEDCT:8839002", "d": [], "t": []}], "preferred_name": "Agranular endoplasmic reticulum, connection with other organelle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523557", "l": "BLOC-1 complex", "d": [], "t": []}], "preferred_name": "BLOC-1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1760026", "l": "speckle focus", "d": [], "t": []}], "preferred_name": "speckle focus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156003", "l": "LUBAC complex", "d": [], "t": []}], "preferred_name": "LUBAC complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230508", "l": "CELLULAR AND SUBCELLULAR STRUCTURES", "d": [], "t": []}], "preferred_name": "CELLULAR AND SUBCELLULAR STRUCTURES", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521632", "l": "7p22-p21", "d": [], "t": []}, {"i": "NCIT:C25110", "l": "7p22-p21", "d": ["A chromosome band present on 7p"], "t": []}], "preferred_name": "7p22-p21", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2613169", "l": "alphav-beta5 integrin-vitronectin complex", "d": [], "t": []}], "preferred_name": "alphav-beta5 integrin-vitronectin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120083", "l": "rough endoplasmic reticulum cisterna", "d": ["A subcompartment of the rough endoplasmic reticulum consisting of lumenal expansion into a flattened, disc-shaped cavity."], "t": []}], "preferred_name": "rough endoplasmic reticulum cisterna", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824448", "l": "uniplex complex", "d": [], "t": []}], "preferred_name": "uniplex complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523372", "l": "Inner segment of photoreceptor", "d": [], "t": []}], "preferred_name": "Inner segment of photoreceptor", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1903103", "l": "potassium:proton antiporter complex", "d": ["A protein complex which is capable of potassium:proton antiporter activity."], "t": []}], "preferred_name": "potassium:proton antiporter complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4689782", "l": "KCNJ8-SUR complex", "d": [], "t": []}], "preferred_name": "KCNJ8-SUR complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167447", "l": "excinuclease repair complex", "d": [], "t": []}], "preferred_name": "excinuclease repair complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896490", "l": "M-CSF:CSF1R complex", "d": [], "t": []}], "preferred_name": "M-CSF:CSF1R complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0038104", "l": "nodal receptor complex", "d": ["A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell."], "t": []}], "preferred_name": "nodal receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137273", "l": "tRNA (m7G46) methyltransferase complex", "d": [], "t": []}], "preferred_name": "tRNA (m7G46) methyltransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824487", "l": "PDGF-CC-receptor alpha complex", "d": [], "t": []}], "preferred_name": "PDGF-CC-receptor alpha complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0030287", "l": "cell wall-bounded periplasmic space", "d": ["The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria."], "t": []}], "preferred_name": "cell wall-bounded periplasmic space", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179843", "l": "Inner layer of plasma membrane", "d": [], "t": []}], "preferred_name": "Inner layer of plasma membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "58.862973002346934", "identifiers": [{"i": "GO:0098643", "l": "banded collagen fibril", "d": ["A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands)."], "t": []}], "preferred_name": "banded collagen fibril", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071112", "l": "alpha4-beta4 integrin-EMILIN-1 complex", "d": ["A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN)."], "t": []}], "preferred_name": "alpha4-beta4 integrin-EMILIN-1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097408", "l": "fibrillary inclusion", "d": ["Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra."], "t": []}], "preferred_name": "fibrillary inclusion", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0020018", "l": "ciliary pocket membrane", "d": ["That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket)."], "t": []}], "preferred_name": "ciliary pocket membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179945", "l": "Part of endoplasmic reticulum vesicle", "d": [], "t": []}], "preferred_name": "Part of endoplasmic reticulum vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1744673", "l": "TIM23 mitochondrial import inner membrane translocase complex location", "d": [], "t": []}], "preferred_name": "TIM23 mitochondrial import inner membrane translocase complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1183331", "l": "Mitochondrion of adipocyte", "d": [], "t": []}], "preferred_name": "Mitochondrion of adipocyte", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325747", "l": "MHC class II protein complex", "d": [], "t": []}], "preferred_name": "MHC class II protein complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009334", "l": "3-phenylpropionate dioxygenase complex", "d": ["Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol)."], "t": []}], "preferred_name": "3-phenylpropionate dioxygenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0009545", "l": "elaioplast", "d": ["A leucoplast in which oil is stored."], "t": []}], "preferred_name": "elaioplast", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230760", "l": "Specialized subunit or derivative of cilium or flagellum, not bacterial", "d": [], "t": []}, {"i": "SNOMEDCT:36486006", "d": [], "t": []}], "preferred_name": "Specialized subunit or derivative of cilium or flagellum, not bacterial", "taxa": []} {"type": "biolink:CellularComponent", "ic": "67.067750146574085", "identifiers": [{"i": "MESH:D002881", "l": "Chromosomes, Human, Pair 12", "d": [], "t": []}, {"i": "UMLS:C0008654", "l": "Chromosomes, Human, Pair 12", "d": [], "t": []}, {"i": "NCIT:C13207", "l": "Human Chromosome 12", "d": ["The designation for each member of the twelfth largest human autosomal chromosome pair. Chromosome 12 spans about 143 million base pairs and represents between 4 and 4.5% of the total DNA in normal diploid cells."], "t": []}, {"i": "SNOMEDCT:17897000", "d": [], "t": []}], "preferred_name": "Chromosomes, Human, Pair 12", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097433", "l": "dense body", "d": ["An electron dense body which may contain granules."], "t": []}], "preferred_name": "dense body", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1621530", "l": "nuclear proteasome regulatory particle, base subcomplex", "d": [], "t": []}], "preferred_name": "nuclear proteasome regulatory particle, base subcomplex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3271527", "l": "tectonic-like complex", "d": [], "t": []}], "preferred_name": "tectonic-like complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4236778", "l": "basolateral cytoplasm", "d": [], "t": []}], "preferred_name": "basolateral cytoplasm", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2334323", "l": "Set of cytoplasmic organelles of neuroglial cell", "d": [], "t": []}], "preferred_name": "Set of cytoplasmic organelles of neuroglial cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070765", "l": "gamma-secretase complex", "d": ["A protein complex that has aspartic-type endopeptidase activity and contains a presenilin catalytic subunit (either PSEN1 or PSEN2), an APH1 subunit (multiple genes and splice variants exist), nicastrin (NCT), and presenilin enhancer (aka PEN-2 or Psenen), as the core complex. Variants of the complex with different subunit compositions differ in localization and specific substrates. Additionally, variants of the complex exist that contain a additional regulatory subunit as well as the four core subunits; known regulatory subunits include gamma-secretase-activating protein (aka gSAP), TMP1 (aka TMED10), and CD147 antigen (aka basigin). Gamma-secretase cleaves type I transmembrane protein substrates, including the cell surface receptor Notch and the amyloid-beta precursor protein."], "t": []}], "preferred_name": "gamma-secretase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120121", "l": "tripartite attachment complex", "d": ["A three-part cytoskeletal structure in kinetoplastid species linking mitochondrial DNA organised in a kinetoplast through the mitochondrial membranes to the basal body."], "t": []}], "preferred_name": "tripartite attachment complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1521102", "l": "22q11-q13", "d": [], "t": []}, {"i": "NCIT:C13757", "l": "22q11-q13", "d": ["A chromosome band present on 22q"], "t": []}], "preferred_name": "22q11-q13", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.257752058161088", "identifiers": [{"i": "GO:0042582", "l": "azurophil granule", "d": ["Primary lysosomal granule readily stainable with a Romanowsky stain."], "t": []}], "preferred_name": "azurophil granule", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0140007", "l": "KICSTOR complex", "d": ["A protein complex that regulates the TORC1 signaling pathway in response to nutrients. The KICSTOR complex is composed of KPTN, ITFG2, C12orf66 and SZT2."], "t": []}], "preferred_name": "KICSTOR complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156847", "l": "haustorium", "d": [], "t": []}], "preferred_name": "haustorium", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166834", "l": "syntrophin complex", "d": [], "t": []}], "preferred_name": "syntrophin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0020026", "l": "merozoite dense granule", "d": ["Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell."], "t": []}], "preferred_name": "merozoite dense granule", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3538559", "l": "Mitochondrion-associated adherens complex location", "d": [], "t": []}], "preferred_name": "Mitochondrion-associated adherens complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754298", "l": "alphaV-beta8 integrin-MMP14-TGFbeta-1 complex", "d": [], "t": []}], "preferred_name": "alphaV-beta8 integrin-MMP14-TGFbeta-1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179112", "l": "C-tubule of triplet microtubule of kinetosome of cilium", "d": [], "t": []}], "preferred_name": "C-tubule of triplet microtubule of kinetosome of cilium", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0098978", "l": "glutamatergic synapse", "d": ["A synapse that uses glutamate as a neurotransmitter."], "t": []}], "preferred_name": "glutamatergic synapse", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4329082", "l": "concave side of sperm head", "d": [], "t": []}], "preferred_name": "concave side of sperm head", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612822", "l": "ITGAV-ITGB6 complex", "d": [], "t": []}], "preferred_name": "ITGAV-ITGB6 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325631", "l": "extrinsic component of endoplasmic reticulum membrane", "d": [], "t": []}], "preferred_name": "extrinsic component of endoplasmic reticulum membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D045524", "l": "Phycobilisomes", "d": [], "t": []}, {"i": "UMLS:C0136979", "l": "Phycobilisomes", "d": [], "t": []}], "preferred_name": "Phycobilisomes", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2610653", "l": "ITGAV-ITGB5-SPP1 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"taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3271511", "l": "protein C inhibitor-TMPRSS11E complex", "d": [], "t": []}], "preferred_name": "protein C inhibitor-TMPRSS11E complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0000346", "l": "transcription export complex", "d": ["The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans."], "t": []}], "preferred_name": "transcription export complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230535", "l": "Nuclear envelope, evagination", "d": [], "t": []}, {"i": "SNOMEDCT:41803006", "d": [], "t": []}], "preferred_name": "Nuclear envelope, evagination", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3271240", "l": "ER-PM peripheral junction", "d": [], "t": []}], "preferred_name": "ER-PM peripheral junction", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523415", "l": "amyloplast ADPG pyrophosphorylase complex", "d": [], "t": []}], "preferred_name": "amyloplast ADPG pyrophosphorylase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0098648", "l": "collagen anchoring fibril", "d": ["A specialised collagen fibril that functions as an anchor, binding to other collagen structures."], "t": []}], "preferred_name": "collagen anchoring fibril", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1902929", "l": "plasma membrane of growing cell tip", "d": ["Any plasma membrane part that is part of a growing cell tip."], "t": []}], "preferred_name": "plasma membrane of growing cell tip", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990712", "l": "HFE-transferrin receptor complex", "d": ["A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription."], "t": []}], "preferred_name": "HFE-transferrin receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990520", "l": "separase-securin complex", "d": ["A protein complex that includes separase (a protease which cleaves cohesin as part of chromosome separation) and securin, a protease inhibitor. Chromosome separation is inhibited until securin is degraded by the Anaphase Promoting Complex (APC)."], "t": []}], "preferred_name": "separase-securin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179050", "l": "Cone Cell Inner Segment", "d": [], "t": []}], "preferred_name": "Cone Cell Inner Segment", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044567", "l": "primary cell wall cellulose synthase complex", "d": ["A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. 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In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97."], "t": []}], "preferred_name": "VCP-NSFL1C complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1622624", "l": "Cul5-RING ubiquitin ligase complex", "d": [], "t": []}], "preferred_name": "Cul5-RING ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2333623", "l": "Plasma membrane of bone marrow stem cell", "d": [], "t": []}], "preferred_name": "Plasma membrane of bone marrow stem cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0682680", "l": "group Ia axon", "d": [], "t": []}], "preferred_name": "group Ia axon", "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.096665005650948", "identifiers": [{"i": "UMLS:C0796365", "l": "8p22", "d": [], "t": []}, {"i": "NCIT:C13388", "l": "8p22", "d": ["A chromosome band present on 8p"], "t": []}], "preferred_name": "8p22", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3546648", "l": "Pick body", "d": [], "t": []}], "preferred_name": "Pick body", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230900", "l": "Elastic fiber, amorphous component", "d": [], "t": []}, {"i": "SNOMEDCT:78941003", "d": [], "t": []}], "preferred_name": "Elastic fiber, amorphous component", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4235098", "l": "Ubp3-Bre5 deubiquitination complex", "d": [], "t": []}], "preferred_name": "Ubp3-Bre5 deubiquitination complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097598", "l": "sperm cytoplasmic droplet", "d": ["A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted."], "t": []}], "preferred_name": "sperm cytoplasmic droplet", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1521633", "l": "7p22.1", "d": [], "t": []}, {"i": "NCIT:C41013", "l": "7p22.1", "d": ["A chromosome band present on 7p"], "t": []}], "preferred_name": "7p22.1", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1520490", "l": "12q12-q14", "d": [], "t": []}, {"i": "NCIT:C24931", "l": "12q12-q14", "d": ["A chromosome band present on 12q"], "t": []}], "preferred_name": "12q12-q14", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166739", "l": "coated vesicle membrane", "d": [], "t": []}], "preferred_name": "coated vesicle membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1818894", "l": "guanyl-nucleotide exchange factor complex", "d": [], "t": []}], "preferred_name": "guanyl-nucleotide exchange factor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990861", "l": "Ubp3-Bre5 deubiquitination complex", "d": ["A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p."], "t": []}], "preferred_name": "Ubp3-Bre5 deubiquitination complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "64.515508441921597", "identifiers": [{"i": "GO:0031967", "l": "organelle envelope", "d": ["A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes."], "t": []}], "preferred_name": "organelle envelope", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2246494", "l": "attachment organelle", "d": [], "t": []}], "preferred_name": "attachment organelle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009428", "l": "bacterial-type flagellum basal body, distal rod, P ring", "d": ["One of the rings of the bacterial-type flagellar basal body; anchors the basal body to the peptidoglycan layer."], "t": []}], "preferred_name": "bacterial-type flagellum basal body, distal rod, P ring", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230902", "l": "Connective tissue microfibrils", "d": [], "t": []}, {"i": "SNOMEDCT:65953004", "d": [], "t": []}], "preferred_name": "Connective tissue microfibrils", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0005925", "l": "focal adhesion", "d": ["A cell-substrate junction that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. In insects focal adhesion has also been referred to as hemi-adherens junction (HAJ)."], "t": []}], "preferred_name": "focal adhesion", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1180327", "l": "Zone of kinetosome of flagellum", "d": [], "t": []}], "preferred_name": "Zone of kinetosome of flagellum", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0333747", "l": "Molluscum bodies", "d": [], "t": []}, {"i": "SNOMEDCT:15503003", "d": [], "t": []}], "preferred_name": "Molluscum bodies", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "MESH:D054351", "l": "Electrical Synapses", "d": [], "t": []}, {"i": "UMLS:C1179884", "l": "Electrical Synapses", "d": [], "t": []}, {"i": "NCIT:C32498", "l": "Electrical Synapse", "d": ["A synapse in which electrical connection is made directly through the cytoplasm, via gap junctions."], "t": []}], "preferred_name": "Electrical Synapses", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4484191", "l": "Neutrophil membrane", "d": [], "t": []}], "preferred_name": "Neutrophil membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754243", "l": "ITGA4-ITGB1-THBS2 complex", "d": [], "t": []}], "preferred_name": "ITGA4-ITGB1-THBS2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2753843", "l": "endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex", "d": [], "t": []}], "preferred_name": "endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896309", "l": "GPI-MT-I complex", "d": [], "t": []}], "preferred_name": "GPI-MT-I complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2334336", "l": "Protoplasm of paneth cell", "d": [], "t": []}], "preferred_name": "Protoplasm of paneth cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "78.040358207728502", "identifiers": [{"i": "NCIT:C13566", "l": "Xq", "d": ["Distal (long) arm of chromosome X"], "t": []}], "preferred_name": "Xq", "taxa": []} {"type": "biolink:CellularComponent", "ic": "81.328771998664962", "identifiers": [{"i": "GO:0009534", "l": "chloroplast thylakoid", "d": ["Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana."], "t": []}], "preferred_name": "chloroplast thylakoid", "taxa": []} {"type": "biolink:CellularComponent", "ic": "84.825678110700707", "identifiers": [{"i": "GO:0099523", "l": "presynaptic cytosol", "d": ["The region of the cytosol consisting of all cytosol that is part of the presynapse."], "t": []}], "preferred_name": "presynaptic cytosol", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5451212", "l": "mannan polymerase II complex", "d": [], "t": []}], "preferred_name": "mannan polymerase II complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2325760", "l": "Neuronal receptor", "d": [], "t": []}], "preferred_name": "Neuronal receptor", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4236792", "l": "inner dense plaque of desmosome", "d": [], "t": []}], "preferred_name": "inner dense plaque of desmosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0038197", "l": "type I interferon receptor complex", "d": ["A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2)."], "t": []}], "preferred_name": "type I interferon receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2326764", "l": "Set of cytoplasmic organelles of totipotent stem cell", "d": [], "t": []}], "preferred_name": "Set of cytoplasmic organelles of totipotent stem cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0000221", "l": "vacuolar proton-transporting V-type ATPase, V1 domain", "d": ["The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane."], "t": []}], "preferred_name": "vacuolar proton-transporting V-type ATPase, V1 domain", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2611777", "l": "RNA polymerase II complex", "d": [], "t": []}], "preferred_name": "RNA polymerase II complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "UMLS:C1520958", "l": "1p33-p32", "d": [], "t": []}, {"i": "NCIT:C24997", "l": "1p33-p32", "d": ["A chromosome band present on 1p"], "t": []}], "preferred_name": "1p33-p32", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0005905", "l": "clathrin-coated pit", "d": ["A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes."], "t": []}], "preferred_name": "clathrin-coated pit", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "UMLS:C1521290", "l": "3p23-p21", "d": [], "t": []}, {"i": "NCIT:C13597", "l": "3p23-p21", "d": ["A chromosome band present on 3p"], "t": []}], "preferred_name": "3p23-p21", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230536", "l": "Perinuclear region of cell", "d": [], "t": []}, {"i": "SNOMEDCT:28568005", "d": [], "t": []}], "preferred_name": "Perinuclear region of cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179087", "l": "Central part of axoneme of cilium", "d": [], "t": []}], "preferred_name": "Central part of axoneme of cilium", "taxa": []} {"type": "biolink:CellularComponent", "ic": "87.17621031280774", "identifiers": [{"i": "GO:0032280", "l": "symmetric synapse", "d": ["A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typically inhibitory."], "t": []}], "preferred_name": "symmetric synapse", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2953770", "l": "Cell body of pyramidal cell of precentral gyrus of cerebral hemisphere", "d": [], "t": []}], "preferred_name": "Cell body of pyramidal cell of precentral gyrus of cerebral hemisphere", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1520642", "l": "15q23-15q24", "d": [], "t": []}, {"i": "NCIT:C13642", "l": "15q23-15q24", "d": ["A chromosome band present on 15q"], "t": []}], "preferred_name": "15q23-15q24", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4325596", "l": "vacuolar protein sorting-associated complex", "d": [], "t": []}], "preferred_name": "vacuolar protein sorting-associated complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C3642146", "l": "6q11-q27", "d": [], "t": []}, {"i": "NCIT:C105369", "l": "6q11-q27", "d": ["A chromosome band present on 6q."], "t": []}], "preferred_name": "6q11-q27", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523478", "l": "linear element", "d": [], "t": []}], "preferred_name": "linear element", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896150", "l": "3M complex", "d": [], "t": []}], "preferred_name": "3M complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230688", "l": "Distinctive cytoplasmic granule of specialized cell", "d": [], "t": []}, {"i": "SNOMEDCT:89670008", "d": [], "t": []}], "preferred_name": "Distinctive cytoplasmic granule of specialized cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071142", "l": "homomeric SMAD protein complex", "d": ["A protein complex composed of a single type of SMAD family proteins. In the absence of Smad4, phosphorylation of R-SMADs results in their homotrimerization. However, these complexes do not appear to import into the nucleus and are assumed to be transcriptionally inactive."], "t": []}], "preferred_name": "homomeric SMAD protein complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071081", "l": "alpha3-beta1 integrin-CD63 complex", "d": ["A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63."], "t": []}], "preferred_name": "alpha3-beta1 integrin-CD63 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0333774", "l": "Cytoplasmic bodies", "d": [], "t": []}, {"i": "SNOMEDCT:79339000", "d": [], "t": []}], "preferred_name": "Cytoplasmic bodies", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097467", "l": "type III terminal bouton", "d": ["Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones."], "t": []}], "preferred_name": "type III terminal bouton", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1622610", "l": "BRCA1-BARD1 complex", "d": [], "t": []}], "preferred_name": "BRCA1-BARD1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0682703", "l": "neuron covering", "d": [], "t": []}], "preferred_name": "neuron covering", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521565", "l": "6q21-qter", "d": [], "t": []}, {"i": "NCIT:C25098", "l": "6q21-qter", "d": ["A chromosome band present on 6q"], "t": []}], "preferred_name": "6q21-qter", "taxa": []} {"type": "biolink:CellularComponent", "ic": "64.336580050109646", "identifiers": [{"i": "MESH:D003599", "l": "Cytoskeleton", "d": [], "t": []}, {"i": "UMLS:C0010853", "l": "Cytoskeleton", "d": [], "t": []}, {"i": "NCIT:C13227", "l": "Cytoskeleton", "d": ["The protein scaffolding (the network of filaments microfilaments, microtubules, intermediate filaments, and their associated proteins) that gives shape, structure, and organization to the cytoplasm and a cell its shape."], "t": []}], "preferred_name": "Cytoskeleton", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821116", "l": "UvrA(2)B(2) complex", "d": [], "t": []}], "preferred_name": "UvrA(2)B(2) complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.595781242041198", "identifiers": [{"i": "GO:0042641", "l": "actomyosin", "d": ["Any complex of actin, myosin, and accessory proteins."], "t": []}], "preferred_name": "actomyosin", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824407", "l": "SufS complex", "d": [], "t": []}], "preferred_name": "SufS complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1953345", "l": "Region of chromosome", "d": [], "t": []}], "preferred_name": "Region of chromosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2332419", "l": "Protoplasm of totipotent stem cell", "d": [], "t": []}], "preferred_name": "Protoplasm of totipotent stem cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690168", "l": "CAX3 homodimer", "d": [], "t": []}], "preferred_name": "CAX3 homodimer", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1623132", "l": "MPF complex", "d": [], "t": []}], "preferred_name": "MPF complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.257752058161088", "identifiers": [{"i": "GO:0009288", "l": "bacterial-type flagellum", "d": ["A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope."], "t": []}], "preferred_name": "bacterial-type flagellum", "taxa": []} {"type": "biolink:CellularComponent", "ic": "69.852086183682616", "identifiers": [{"i": "MESH:D002888", "l": "Chromosomes, Human, Pair 19", "d": [], "t": []}, {"i": "UMLS:C0008661", "l": "Chromosomes, Human, Pair 19", "d": [], "t": []}, {"i": "NCIT:C13214", "l": "Human Chromosome 19", "d": ["The designation for each member of the nineteenth largest human autosomal chromosome pair. 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The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "host cell chloroplast part", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097728", "l": "9+0 motile cilium", "d": ["A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme)."], "t": []}], "preferred_name": "9+0 motile cilium", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070354", "l": "GATA2-TAL1-TCF3-Lmo2 complex", "d": ["A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis."], "t": []}], "preferred_name": "GATA2-TAL1-TCF3-Lmo2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754155", "l": "U12-type catalytic step 1 spliceosome", "d": [], "t": []}], "preferred_name": "U12-type catalytic step 1 spliceosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1511546", "l": "Crosslinker", "d": [], "t": []}, {"i": "NCIT:C32407", "l": "Crosslinker", "d": ["A protein that links cytoskeletal filaments to one another and modulates both the formation and stability of cellular structures."], "t": []}], "preferred_name": "Crosslinker", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230747", "l": "Flagellum, not bacterial", "d": [], "t": []}, {"i": "SNOMEDCT:51343004", "d": [], "t": []}], "preferred_name": "Flagellum, not bacterial", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071261", "l": "Ssh1 translocon complex", "d": ["A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences."], "t": []}], "preferred_name": "Ssh1 translocon complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690949", "l": "host cell centrosome", "d": [], "t": []}], "preferred_name": "host cell centrosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167115", "l": "NURF complex", "d": [], "t": []}], "preferred_name": "NURF complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167314", "l": "virion transport vesicle", "d": [], "t": []}], "preferred_name": "virion transport vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "86.296221842381144", "identifiers": [{"i": "GO:0005901", "l": "caveola", "d": ["A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. 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It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex."], "t": []}], "preferred_name": "potassium ion-transporting ATPase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0014776", "l": "Red Cell Ghost", "d": [], "t": []}], "preferred_name": "Red Cell Ghost", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612401", "l": "RC complex", "d": [], "t": []}], "preferred_name": "RC complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070114", "l": "organellar chromatophore outer membrane", "d": ["The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore."], "t": []}], "preferred_name": "organellar chromatophore outer membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030895", "l": "apolipoprotein B mRNA editing enzyme complex", "d": ["Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). 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The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript."], "t": []}], "preferred_name": "Ire1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754219", "l": "ITGAV-ITGB3-ADAM15 complex", "d": [], "t": []}], "preferred_name": "ITGAV-ITGB3-ADAM15 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821117", "l": "UvrB dimer", "d": [], "t": []}], "preferred_name": "UvrB dimer", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3271983", "l": "host outer membrane", "d": [], "t": []}], "preferred_name": "host outer membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1818842", "l": "myosin XVIII complex", "d": [], "t": []}], "preferred_name": "myosin XVIII complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523437", "l": "glutamyl-tRNA(Gln) amidotransferase complex location", "d": [], "t": []}], "preferred_name": "glutamyl-tRNA(Gln) amidotransferase complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167410", "l": "phosphatidylinositol 3-kinase complex, class IA", "d": [], "t": []}], "preferred_name": "phosphatidylinositol 3-kinase complex, class IA", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009515", "l": "granal stacked thylakoid", "d": ["Appressed thylakoid membranes that are part of a granum (stacked regions). 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Recognition of the start codon triggers downstream steps in the pathway, including eIF1 dissociation; Pi release from eIF2; and conversion to the closed, scanning-arrested conformation of the PIC."], "t": []}], "preferred_name": "eukaryotic 48S preinitiation complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230762", "l": "INTRACYTOPLASMIC MEMBRANE SYSTEMS AND ASSOCIATED STRUCTURES", "d": [], "t": []}], "preferred_name": "INTRACYTOPLASMIC MEMBRANE SYSTEMS AND ASSOCIATED STRUCTURES", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4329159", "l": "triglyceride-rich plasma lipoprotein particle", "d": [], "t": []}], "preferred_name": "triglyceride-rich plasma lipoprotein particle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156612", "l": "IPAF inflammasome complex", "d": [], "t": []}], "preferred_name": "IPAF inflammasome complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754334", "l": "alphaX-beta2 integrin-ICAM-4 complex", "d": [], "t": []}], "preferred_name": "alphaX-beta2 integrin-ICAM-4 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0042644", "l": "chloroplast nucleoid", "d": ["The region of a chloroplast to which the DNA is confined."], "t": []}], "preferred_name": "chloroplast nucleoid", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896372", "l": "FtsBL complex", "d": [], "t": []}], "preferred_name": "FtsBL complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2753453", "l": "FHF complex", "d": [], "t": []}], "preferred_name": "FHF complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "84.825678110700707", "identifiers": [{"i": "GO:0039714", "l": "cytoplasmic viral factory", "d": ["A viral factory located in the cytoplasm of a host cell."], "t": []}], "preferred_name": "cytoplasmic viral factory", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990225", "l": "rhoptry neck", "d": ["Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion."], "t": []}], "preferred_name": "rhoptry neck", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2752238", "l": "nurse cell ring canal", "d": [], "t": []}], "preferred_name": "nurse cell ring canal", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "UMLS:C1521008", "l": "1q32-q41", "d": [], "t": []}, {"i": "NCIT:C13973", "l": "1q32-q41", "d": ["A chromosome band present on 1q"], "t": []}], "preferred_name": "1q32-q41", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1710781", "l": "14q13.3", "d": [], "t": []}, {"i": "NCIT:C44957", "l": "14q13.3", "d": ["Part of the chromosome bands present on the long (q) arm of chromosome 14."], "t": []}], "preferred_name": "14q13.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": "85.520017001314969", "identifiers": [{"i": "GO:0000808", "l": "origin recognition complex", "d": ["A multisubunit complex that is located at the replication origins of a chromosome."], "t": []}], "preferred_name": "origin recognition complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167125", "l": "origin recognition complex location", "d": [], "t": []}], "preferred_name": "origin recognition complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.624156395578254", "identifiers": [{"i": "GO:0009425", "l": "bacterial-type flagellum basal body", "d": ["One of the three major substructures of the bacterial-type flagellum, the basal body is embedded in the cell envelope (the plasma membrane, peptidoglycan cell wall, and, if one is present, the outer membrane); it houses the secretion apparatus that exports the more distal components and the flagellar motor."], "t": []}], "preferred_name": "bacterial-type flagellum basal body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0005797", "l": "Golgi medial cisterna", "d": ["The middle Golgi cisterna (or cisternae)."], "t": []}], "preferred_name": "Golgi medial cisterna", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0097593", "l": "ventral disc microtubule array", "d": ["A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane."], "t": []}], "preferred_name": "ventral disc microtubule array", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167173", "l": "U4/U6 x U5 tri-snRNP complex", "d": [], "t": []}], "preferred_name": "U4/U6 x U5 tri-snRNP complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "86.296221842381144", "identifiers": [{"i": "GO:0030686", "l": "90S preribosome", "d": ["A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins."], "t": []}], "preferred_name": "90S preribosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "87.17621031280774", "identifiers": [{"i": "GO:0002187", "l": "mitochondrial creatine kinase complex", "d": ["An octomeric protein complex having creatine kinase activity."], "t": []}], "preferred_name": "mitochondrial creatine kinase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2610708", "l": "Vamp3-Vamp4-Stx16 complex", "d": [], "t": []}], "preferred_name": "Vamp3-Vamp4-Stx16 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1819312", "l": "MHC class Ib protein complex", "d": [], "t": []}], "preferred_name": "MHC class Ib protein complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1625133", "l": "interleukin-12 complex", "d": [], "t": []}], "preferred_name": "interleukin-12 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097463", "l": "gemmule", "d": ["Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex."], "t": []}], "preferred_name": "gemmule", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0110016", "l": "B-WICH complex", "d": ["A chromatin remodeling complex that positively regulates histone H3 acetylation, in particular H3K9, by recruiting histone acetyltransferases to rDNA gene regions. 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Although it contains several catalytic subunits it is not clear which functions are carried out by the complex itself."], "t": []}], "preferred_name": "B-WICH complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156571", "l": "host cell viral assembly compartment", "d": [], "t": []}], "preferred_name": "host cell viral assembly compartment", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030905", "l": "retromer, tubulation complex", "d": ["The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodeling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6."], "t": []}], "preferred_name": "retromer, tubulation complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521374", "l": "4p14-q21", "d": [], "t": []}, {"i": "NCIT:C14009", "l": "4p14-q21", "d": ["A chromosome band present on 4p"], "t": []}], "preferred_name": "4p14-q21", "taxa": []} {"type": "biolink:CellularComponent", "ic": "86.296221842381144", "identifiers": [{"i": "UMLS:C1520399", "l": "11q22.3", "d": [], "t": []}, {"i": "NCIT:C13799", "l": "11q22.3", "d": ["A chromosome band present on 11q"], "t": []}], "preferred_name": "11q22.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "GO:0034361", "l": "very-low-density lipoprotein particle", "d": ["A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver."], "t": []}], "preferred_name": "very-low-density lipoprotein particle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754385", "l": "protocadherin-alpha-protocadherin-gamma complex", "d": [], "t": []}], "preferred_name": "protocadherin-alpha-protocadherin-gamma complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "73.96081290057171", "identifiers": [{"i": "GO:0042470", "l": "melanosome", "d": ["A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. 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It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network."], "t": []}], "preferred_name": "internal side of mycolate outer membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4691127", "l": "basal distal dendrite", "d": [], "t": []}], "preferred_name": "basal distal dendrite", "taxa": []} {"type": "biolink:CellularComponent", "ic": "57.225325349899627", "identifiers": [{"i": "GO:0000792", "l": "heterochromatin", "d": ["A compact and highly condensed form of chromatin that is refractory to transcription."], "t": []}], "preferred_name": "heterochromatin", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.95209094877535", "identifiers": [{"i": "GO:0030057", "l": "desmosome", "d": ["A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism."], "t": []}], "preferred_name": "desmosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612818", "l": "ITGAV-ITGB3 complex", "d": [], "t": []}], "preferred_name": "ITGAV-ITGB3 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071113", "l": "alphaIIb-beta3 integrin-ICAM-4 complex", "d": ["A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4."], "t": []}], "preferred_name": "alphaIIb-beta3 integrin-ICAM-4 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:1990101", "l": "DnaA-oriC complex", "d": ["A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle."], "t": []}], "preferred_name": "DnaA-oriC complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0032921", "l": "sarcosine oxidase complex", "d": ["A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity."], "t": []}], "preferred_name": "sarcosine oxidase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "76.760845946125343", "identifiers": [{"i": "NCIT:C13384", "l": "7q", "d": ["Distal (long) arm of chromosome 7"], "t": []}], "preferred_name": "7q", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0002096", "l": "polkadots", "d": ["A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals."], "t": []}], "preferred_name": "polkadots", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0019907", "l": "cyclin-dependent protein kinase activating kinase holoenzyme complex", "d": ["A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH."], "t": []}], "preferred_name": "cyclin-dependent protein kinase activating kinase holoenzyme complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030932", "l": "amyloplast ADPG pyrophosphorylase complex", "d": ["An ADPG pyrophosphorylase complex found in the amyloplast."], "t": []}], "preferred_name": "amyloplast ADPG pyrophosphorylase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2248600", "l": "carotenoid vesicle", "d": [], "t": []}], "preferred_name": "carotenoid vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137264", "l": "protein phosphatase inhibitor complex", "d": [], "t": []}], "preferred_name": "protein phosphatase inhibitor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0225328", "l": "Fibril - cell component", "d": [], "t": []}, {"i": "SNOMEDCT:88921000", "d": [], "t": []}], "preferred_name": "Fibril - cell component", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0043700", "l": "pterinosome", "d": ["A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. 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The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases."], "t": []}], "preferred_name": "Ddb1-Wdr21 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "68.616682006965917", "identifiers": [{"i": "GO:1902554", "l": "serine/threonine protein kinase complex", "d": ["A protein complex which is capable of protein serine/threonine kinase activity."], "t": []}], "preferred_name": "serine/threonine protein kinase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2611043", "l": "ITGA6-ITGB4-LAMA5 complex", "d": [], "t": []}], "preferred_name": "ITGA6-ITGB4-LAMA5 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896281", "l": "raps-insc complex", "d": [], "t": []}], "preferred_name": "raps-insc complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0070187", "l": "shelterin complex", "d": ["A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. 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null, "identifiers": [{"i": "UMLS:C2329078", "l": "Protoplasm of reticular cell", "d": [], "t": []}], "preferred_name": "Protoplasm of reticular cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821193", "l": "ventral disc overlap zone", "d": [], "t": []}], "preferred_name": "ventral disc overlap zone", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521708", "l": "8p23-p22", "d": [], "t": []}, {"i": "NCIT:C26541", "l": "8p23-p22", "d": ["A chromosome band present on 8p"], "t": []}], "preferred_name": "8p23-p22", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754381", "l": "MAML3-RBP-Jkappa-ICN1 complex", "d": [], "t": []}], "preferred_name": "MAML3-RBP-Jkappa-ICN1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0005859", "l": "muscle myosin complex", "d": ["A filament 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"identifiers": [{"i": "UMLS:C2243180", "l": "vacuolar proton-transporting V-type ATPase complex", "d": [], "t": []}], "preferred_name": "vacuolar proton-transporting V-type ATPase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2244317", "l": "proteasome accessory complex", "d": [], "t": []}], "preferred_name": "proteasome accessory complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3269017", "l": "interferon regulatory factor complex", "d": [], "t": []}], "preferred_name": "interferon regulatory factor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167107", "l": "mRNA cleavage stimulating factor complex", "d": [], "t": []}], "preferred_name": "mRNA cleavage stimulating factor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5380090", "l": "chloroplast vesicle", "d": [], "t": 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"biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1820105", "l": "EKC/KEOPS complex", "d": [], "t": []}], "preferred_name": "EKC/KEOPS complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "69.205477320482444", "identifiers": [{"i": "GO:0030133", "l": "transport vesicle", "d": ["Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell."], "t": []}], "preferred_name": "transport vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.95209094877535", "identifiers": [{"i": "GO:0005795", "l": "Golgi stack", "d": ["The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. 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(NCI)"], "t": []}], "preferred_name": "Nucleosomal Repeat Length", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166653", "l": "subpellicular microtubule", "d": [], "t": []}], "preferred_name": "subpellicular microtubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179085", "l": "adaptin location", "d": [], "t": []}], "preferred_name": "adaptin location", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0052718", "l": "tRNA-specific adenosine-34 deaminase complex", "d": ["A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. 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The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs."], "t": []}], "preferred_name": "microprocessor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2335621", "l": "Axon of motor neuron", "d": [], "t": []}], "preferred_name": "Axon of motor neuron", "taxa": []} {"type": "biolink:CellularComponent", "ic": "79.629646129707766", "identifiers": [{"i": "GO:0046930", "l": "pore complex", "d": ["A protein complex providing a discrete opening in a membrane that allows the passage of gases and/or liquids."], "t": []}], "preferred_name": "pore complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120228", "l": "outer dynein arm docking complex", "d": ["A complex which stabilizes the binding of and correctly positions the outer dynein arm complex along an A-tubule of the flagellar axoneme outer doublet microtubules."], "t": []}], "preferred_name": "outer dynein arm docking complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "65.668838905634516", "identifiers": [{"i": "GO:0030428", "l": "cell septum", "d": ["A structure composed of peptidoglycan and often chitin in addition to other materials. 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Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template."], "t": []}], "preferred_name": "RNA polymerase I complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0098853", "l": "endoplasmic reticulum-vacuole membrane contact site", "d": ["A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes."], "t": []}], "preferred_name": "endoplasmic reticulum-vacuole membrane contact site", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0002179", "l": "homodimeric serine palmitoyltransferase complex", "d": ["A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine."], "t": []}], "preferred_name": "homodimeric serine palmitoyltransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0061845", "l": "neuron projection branch point", "d": ["The location where a secondary projection arises from a neuron projection."], "t": []}], "preferred_name": "neuron projection branch point", "taxa": []} {"type": "biolink:CellularComponent", "ic": "85.520017001314969", "identifiers": [{"i": "GO:0035371", "l": "microtubule plus-end", "d": ["The growing (plus) end of a microtubule. 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Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen."], "t": []}], "preferred_name": "nitrogenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.95209094877535", "identifiers": [{"i": "GO:0014069", "l": "postsynaptic density", "d": ["An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components."], "t": []}], "preferred_name": "postsynaptic density", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0098520", "l": "excitatory neuromuscular junction", "d": ["The junction between the axon of a motor neuron and a muscle fiber. 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The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate."], "t": []}], "preferred_name": "chlorosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0002197", "l": "xanthine dehydrogenase complex", "d": ["A homodimeric protein complex having xanthine dehydrogenase activity."], "t": []}], "preferred_name": "xanthine dehydrogenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2755010", "l": "IgNAR immunoglobulin complex", "d": [], "t": []}], "preferred_name": "IgNAR immunoglobulin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166811", "l": "proteasome activator complex location", "d": [], "t": []}], "preferred_name": "proteasome activator complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.096665005650948", "identifiers": [{"i": "NCIT:C45822", "l": "Locus", "d": ["The position of a gene or a chromosomal marker on a chromosome; also, a stretch of DNA at a particular place on a particular chromosome. The use of locus is sometimes restricted to mean regions of DNA that are expressed."], "t": []}], "preferred_name": "Locus", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0032152", "l": "meiotic septin complex", "d": ["A heterooligomeric septin complex that acts during meiotic cell division."], "t": []}], "preferred_name": "meiotic septin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:1990819", "l": "mating projection actin fusion focus", "d": ["A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. 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It is thought that rod disc membranes arise as evaginations of the ciliary membrane near the base of the outer segment, which then become completely separated from the ciliary membrane, during the development of the rod outer segment."], "t": []}], "preferred_name": "rod photoreceptor disc membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179096", "l": "Tangential link of axoneme of cilium", "d": [], "t": []}], "preferred_name": "Tangential link of axoneme of cilium", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179911", "l": "Matrix of Golgi vesicle", "d": [], "t": []}], "preferred_name": "Matrix of Golgi vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3476764", "l": "Y chromosome AZFb region", "d": [], "t": []}], "preferred_name": "Y chromosome AZFb region", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0043655", "l": "host extracellular space", "d": ["The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream."], "t": []}], "preferred_name": "host extracellular space", "taxa": []} {"type": "biolink:CellularComponent", "ic": "67.624993841046106", "identifiers": [{"i": "MESH:D002889", "l": "Chromosomes, Human, Pair 2", "d": [], "t": []}, {"i": "UMLS:C0008662", "l": "Chromosomes, Human, Pair 2", "d": [], "t": []}, {"i": "NCIT:C13215", "l": "Human Chromosome 2", "d": ["The designation for each member of the second largest human autosomal chromosome pair. 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Subsequent activation of these pre-RCs results in bi-directional DNA replication that originates at or close to the ORC DNA binding sites. 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Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen."], "t": []}], "preferred_name": "iron-iron nitrogenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5451092", "l": "pro-centriole", "d": [], "t": []}], "preferred_name": "pro-centriole", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C2825982", "l": "15q25.1", "d": [], "t": []}, {"i": "NCIT:C82132", "l": "15q25.1", "d": ["A chromosome band present on 15q."], "t": []}], "preferred_name": "15q25.1", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0031040", "l": "micronucleus", "d": ["A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell."], "t": []}], "preferred_name": "micronucleus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2752377", "l": "Schwann cell compact myelin", "d": [], "t": []}], "preferred_name": "Schwann cell compact myelin", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1520409", "l": "11q24.1-q24.3", "d": [], "t": []}, {"i": "NCIT:C13517", "l": "11q24.1-q24.3", "d": ["A chromosome band present on 11q"], "t": []}], "preferred_name": "11q24.1-q24.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896465", "l": "NKX2.5 complex", "d": [], "t": []}], "preferred_name": "NKX2.5 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754112", "l": "GT-AG precatalytic spliceosome", "d": [], "t": []}], "preferred_name": "GT-AG precatalytic spliceosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612821", "l": "integrin alphav-beta6 complex", "d": [], "t": []}], "preferred_name": "integrin alphav-beta6 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D018244", "l": "Chromosomes, Artificial, Yeast", "d": [], "t": []}], "preferred_name": "Chromosomes, Artificial, Yeast", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070017", "l": "alphav-beta3 integrin-thrombospondin complex", "d": ["A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin."], "t": []}], "preferred_name": "alphav-beta3 integrin-thrombospondin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0042151", "l": "nematocyst", "d": ["An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus."], "t": []}], "preferred_name": "nematocyst", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "UMLS:C1521484", "l": "5q23.2", "d": [], "t": []}, {"i": "NCIT:C25081", "l": "5q23.2", "d": ["A chromosome band present on 5q"], "t": []}], "preferred_name": "5q23.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5450343", "l": "gamma-tubulin large complex, interphase microtubule organizing center", "d": [], "t": []}], "preferred_name": "gamma-tubulin large complex, interphase microtubule organizing center", "taxa": []} {"type": "biolink:CellularComponent", "ic": "87.17621031280774", "identifiers": [{"i": "UMLS:C1520951", "l": "1p32", "d": [], "t": []}, {"i": "NCIT:C13478", "l": "1p32", "d": ["A chromosome band present on 1p"], "t": []}], "preferred_name": "1p32", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4689972", "l": "METTL3-METTL14-WTAP methyltransferase complex", "d": [], "t": []}], "preferred_name": "METTL3-METTL14-WTAP methyltransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2246998", "l": "high-affinity iron permease complex", "d": [], "t": []}], "preferred_name": "high-affinity iron permease complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0033099", "l": "attachment organelle", "d": ["A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division."], "t": []}], "preferred_name": "attachment organelle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521548", "l": "6p24-p23", "d": [], "t": []}, {"i": "NCIT:C14011", "l": "6p24-p23", "d": ["A chromosome band present on 6p"], "t": []}], "preferred_name": "6p24-p23", "taxa": []} {"type": "biolink:CellularComponent", "ic": "76.384164896235731", "identifiers": [{"i": "UMLS:C1520860", "l": "19q13.2", "d": [], "t": []}, {"i": "NCIT:C13655", "l": "19q13.2", "d": ["A chromosome band present on 19q"], "t": []}], "preferred_name": "19q13.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4327174", "l": "Tapasin-ERp57 complex", "d": [], "t": []}], "preferred_name": "Tapasin-ERp57 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1180013", "l": "Endoplasmic reticulum tubule", "d": [], "t": []}], "preferred_name": "Endoplasmic reticulum tubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0039620", "l": "T=7 icosahedral viral capsid", "d": ["The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres."], "t": []}], "preferred_name": "T=7 icosahedral viral capsid", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0043198", "l": "dendritic shaft", "d": ["Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines."], "t": []}], "preferred_name": "dendritic shaft", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1520977", "l": "1p36.13-p36.11", "d": [], "t": []}, {"i": "NCIT:C13694", "l": "1p36.13-p36.11", "d": ["A chromosome band present on 1p"], "t": []}], "preferred_name": "1p36.13-p36.11", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071115", "l": "alpha5-beta1 integrin-endostatin complex", "d": ["A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen."], "t": []}], "preferred_name": "alpha5-beta1 integrin-endostatin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2611010", "l": "Rad3-Rad26 complex", "d": [], "t": []}], "preferred_name": "Rad3-Rad26 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "NCIT:C13293", "l": "TATA Box", "d": ["A consensus sequence found in the promoter region of most genes transcribed by eukaryotic RNA polymerase II. 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SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)."], "t": []}], "preferred_name": "cytoplasmic SCF ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754289", "l": "ITGA3-ITGB1-THBS1 complex", "d": [], "t": []}], "preferred_name": "ITGA3-ITGB1-THBS1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070014", "l": "sucrase-isomaltase complex", "d": ["A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities."], "t": []}], "preferred_name": "sucrase-isomaltase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097546", "l": "ciliary base", "d": ["Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. 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It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles."], "t": []}], "preferred_name": "nucleolus-like body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031615", "l": "cytosolic proteasome regulatory particle, lid subcomplex", "d": ["The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex."], "t": []}], "preferred_name": "cytosolic proteasome regulatory particle, lid subcomplex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5380214", "l": "matrilin-1 complex", "d": [], "t": []}], "preferred_name": "matrilin-1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3546553", "l": "viral terminase complex", "d": [], "t": []}], "preferred_name": "viral terminase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0682565", "l": "myocyte structure", "d": [], "t": []}], "preferred_name": "myocyte structure", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230737", "l": "Continuous microtubules of spindle", "d": [], "t": []}, {"i": "SNOMEDCT:74951006", "d": [], "t": []}], "preferred_name": "Continuous microtubules of spindle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "GO:0097227", "l": "sperm annulus", "d": ["The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity."], "t": []}], "preferred_name": "sperm annulus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2611078", "l": "ITGB3-ITGAV-CD47 complex", "d": [], "t": []}], "preferred_name": "ITGB3-ITGAV-CD47 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "72.096711991307572", "identifiers": [{"i": "GO:0042175", "l": "nuclear outer membrane-endoplasmic reticulum membrane network", "d": ["The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane."], "t": []}], "preferred_name": "nuclear outer membrane-endoplasmic reticulum membrane network", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325708", "l": "microsporocyte nucleus", "d": [], "t": []}], "preferred_name": "microsporocyte nucleus", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "UMLS:C1520371", "l": "11p15.3-p15.1", "d": [], "t": []}, {"i": "NCIT:C41012", "l": "11p15.3-p15.1", "d": ["A chromosome band present on 11p"], "t": []}], "preferred_name": "11p15.3-p15.1", "taxa": []} {"type": "biolink:CellularComponent", "ic": "87.17621031280774", "identifiers": [{"i": "UMLS:C1520515", "l": "12q24.13", "d": [], "t": []}, {"i": "NCIT:C24940", "l": "12q24.13", "d": ["A chromosome band present on 12q"], "t": []}], "preferred_name": "12q24.13", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3822745", "l": "Hpa3 (homo-)dimer", "d": [], "t": []}], "preferred_name": "Hpa3 (homo-)dimer", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0043528", "l": "tRNA (m2G10) methyltransferase complex", "d": ["A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. 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This complex might have chaperone activity."], "t": []}], "preferred_name": "RPAP3/R2TP/prefoldin-like complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325540", "l": "lignin network", "d": [], "t": []}], "preferred_name": "lignin network", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166917", "l": "mitochondrial proton-transporting ATP synthase, catalytic core", "d": [], "t": []}], "preferred_name": "mitochondrial proton-transporting ATP synthase, catalytic core", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4326883", "l": "ADDL complex", "d": [], "t": []}], "preferred_name": "ADDL complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034680", "l": "integrin alpha10-beta1 complex", "d": ["An integrin complex that comprises one alpha10 subunit and one beta1 subunit."], "t": []}], "preferred_name": "integrin alpha10-beta1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005595", "l": "collagen type XII trimer", "d": ["A collagen homotrimer of alpha1(XII) chains; 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It consists of the basal lamina plus an associated layer of reticulin fibers."], "t": []}, {"i": "UMLS:C0004799", "l": "Basement membrane", "d": [], "t": []}, {"i": "NCIT:C13191", "l": "Basement Membrane", "d": ["Ubiquitous supportive tissue adjacent to epithelium and around smooth and striated muscle cells. This tissue contains intrinsic macromolecular components such as collagen, laminin, and sulfated proteoglycans. As seen by light microscopy one of its subdivisions is the basal (basement) lamina."], "t": []}, {"i": "UBERON:0005769", "l": "basement membrane of epithelium", "d": ["An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina."], "t": []}], "preferred_name": "basement membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230657", "l": "Micropinocytosis vermiformis channel", "d": [], "t": []}, {"i": "SNOMEDCT:18208007", "d": [], "t": []}], "preferred_name": "Micropinocytosis vermiformis channel", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754727", "l": "Cdc42 GTPase complex", "d": [], "t": []}], "preferred_name": "Cdc42 GTPase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179925", "l": "Cytoplasmic dense body", "d": [], "t": []}], "preferred_name": "Cytoplasmic dense body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0000311", "l": "plastid large ribosomal subunit", "d": ["The larger of the two subunits of a plastid ribosome. 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Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase."], "t": []}], "preferred_name": "mast cell granule", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690709", "l": "Mps2-Bbp1-Spc29 complex", "d": [], "t": []}], "preferred_name": "Mps2-Bbp1-Spc29 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "72.192919893585724", "identifiers": [{"i": "MESH:D054829", "l": "RING Finger Domains", "d": [], "t": []}, {"i": "UMLS:C1521759", "l": "Ring Finger Domain", "d": [], "t": []}, {"i": "NCIT:C13746", "l": "Ring Finger Domain", "d": ["The RING finger is a specialized type of Zn-finger consisting of 40 to 60 residues, which has the consensus sequence CX2CX(9-39)CX(1-3)HX(2-3)C/HX2CX(4-48)CX2C, that binds two atoms of zinc, and is involved in mediating protein-protein interactions. The RING domain mediates the interaction with the appropriate E2 enzyme. Unlike HECT E3 enzymes that form a thiol-ester with ubiquitin, RING fingers likely mediate ubiquitination by facilitating the direct transfer of ubiquitin from E2 enzyme to lysine residues on the target substrate."], "t": []}], "preferred_name": "RING Finger Domains", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005969", "l": "serine-pyruvate aminotransferase complex", "d": ["An protein homedieric complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate."], "t": []}], "preferred_name": "serine-pyruvate aminotransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.95209094877535", "identifiers": [{"i": "GO:0000152", "l": "nuclear ubiquitin ligase complex", "d": ["A ubiquitin ligase complex found in the nucleus."], "t": []}], "preferred_name": "nuclear ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3891816", "l": "dinoflagellate cingulum", "d": [], "t": []}], "preferred_name": "dinoflagellate cingulum", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3269174", "l": "PBF transcription complex", "d": [], "t": []}], "preferred_name": "PBF transcription complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "71.725339136842422", "identifiers": [{"i": "GO:0032994", "l": "protein-lipid complex", "d": ["A macromolecular complex containing separate protein and lipid molecules. 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Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p)."], "t": []}], "preferred_name": "nuclear pore linkers", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179145", "l": "Junctional process of muscle cell", "d": [], "t": []}], "preferred_name": "Junctional process of muscle cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0140510", "l": "mitotic nuclear bridge", "d": ["A narrow constricted region of the nucleus that forms around the anaphase spindle during closed mitosis, and connects the main portions of the newly forming daughter nuclei."], "t": []}], "preferred_name": "mitotic nuclear bridge", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166865", "l": "Golgi medial cisterna", "d": [], "t": []}], "preferred_name": "Golgi medial cisterna", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4327168", "l": "CENP-T-W-S-X complex", "d": [], "t": []}], "preferred_name": "CENP-T-W-S-X complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137196", "l": "SLBP-SLIP1 complex", "d": [], "t": []}], "preferred_name": "SLBP-SLIP1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990726", "l": "Lsm1-7-Pat1 complex", "d": ["A conserved, heteroheptameric, cytoplasmic protein complex composed of Lsm1, Lsm2, Lsm3, Lsm4, Lsm5, Lsm6, Lsm7, and Pat1, or orthologs thereof, that shows a strong binding preference for oligoadenylated RNAs over polyadenylated RNAs. May bind further associated proteins. Facilitates the deadenylation-dependent decapping of mRNA in the P-body thereby regulating mRNA decay and subsequent degradation by the 5' to 3' pathway."], "t": []}], "preferred_name": "Lsm1-7-Pat1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "UMLS:C1520756", "l": "17q11", "d": [], "t": []}, {"i": "NCIT:C13981", "l": "17q11", "d": ["A chromosome band present on 17q"], "t": []}], "preferred_name": "17q11", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0062245", "l": "double membrane vesicle viral factory inner membrane", "d": ["The inner of the two endoplasmic reticulum-derived lipid bilayer membranes that bound a double membrane vesicle viral factory."], "t": []}], "preferred_name": "double membrane vesicle viral factory inner membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1515494", "l": "9p12", "d": [], "t": []}, {"i": "NCIT:C28704", "l": "9p12", "d": ["A chromosome band present on 9p"], "t": []}], "preferred_name": "9p12", "taxa": []} {"type": "biolink:CellularComponent", "ic": "78.28002550197246", "identifiers": [{"i": "GO:0005577", "l": "fibrinogen complex", "d": ["A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds."], "t": []}], "preferred_name": "fibrinogen complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821293", "l": "stromal side of plastid thylakoid membrane", "d": [], "t": []}], "preferred_name": "stromal side of plastid thylakoid membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034752", "l": "cytosolic aryl hydrocarbon receptor complex", "d": ["An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP."], "t": []}], "preferred_name": "cytosolic aryl hydrocarbon receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1521702", "l": "8p21.1", "d": [], "t": []}, {"i": "NCIT:C25119", "l": "8p21.1", "d": ["A chromosome band present on 8p"], "t": []}], "preferred_name": "8p21.1", "taxa": []} {"type": "biolink:CellularComponent", "ic": "82.153612663897817", "identifiers": [{"i": "GO:0031985", "l": "Golgi cisterna", "d": ["Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex."], "t": []}], "preferred_name": "Golgi cisterna", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D000088502", "l": "Lamellar Bodies", "d": [], "t": []}, {"i": "UMLS:C0230698", "l": "lamellar body", "d": [], "t": []}, {"i": "SNOMEDCT:38533002", "d": [], "t": []}], "preferred_name": "Lamellar Bodies", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612782", "l": "endoplasmic reticulum network complex", "d": [], "t": []}], "preferred_name": "endoplasmic reticulum network complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044568", "l": "secondary cell wall cellulose synthase complex", "d": ["A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4."], "t": []}], "preferred_name": "secondary cell wall cellulose synthase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0005861", "l": "troponin complex", "d": ["A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction."], "t": []}], "preferred_name": "troponin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325796", "l": "AP-1 adaptor complex location", "d": [], "t": []}], "preferred_name": "AP-1 adaptor complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137274", "l": "Cdr2 medial cortical node complex", "d": [], "t": []}], "preferred_name": "Cdr2 medial cortical node complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0060388", "l": "vitelline envelope", "d": ["A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization."], "t": []}], "preferred_name": "vitelline envelope", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120105", "l": "mitotic actomyosin contractile ring, intermediate layer", "d": ["The region of the mitotic actomyosin ring in between the proximal layer and the actin filament layer. This region contains the accessory protein network, some actin filaments and connections between the proximal layer and the actin filament layer."], "t": []}], "preferred_name": "mitotic actomyosin contractile ring, intermediate layer", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166714", "l": "cyclin-dependent protein kinase holoenzyme complex location", "d": [], "t": []}], "preferred_name": "cyclin-dependent protein kinase holoenzyme complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1817582", "l": "stromule", "d": [], "t": []}], "preferred_name": "stromule", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612530", "l": "etioplast envelope", "d": [], "t": []}], "preferred_name": "etioplast envelope", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1753273", "l": "sodium pump location", "d": [], "t": []}], "preferred_name": "sodium pump location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137263", "l": "protein kinase 5 complex", "d": [], "t": []}], "preferred_name": "protein kinase 5 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0000506", "l": "glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex", "d": ["An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast."], "t": []}], "preferred_name": "glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167416", "l": "acetolactate synthase complex", "d": [], "t": []}], "preferred_name": "acetolactate synthase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990455", "l": "PTEN phosphatase complex", "d": ["A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function."], "t": []}], "preferred_name": "PTEN phosphatase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070622", "l": "UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex", "d": ["A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits."], "t": []}], "preferred_name": "UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2753440", "l": "macropinocytic cup cytoskeleton", "d": [], "t": []}], "preferred_name": "macropinocytic cup cytoskeleton", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031478", "l": "myosin VIII complex", "d": ["A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain."], "t": []}], "preferred_name": "myosin VIII complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2755005", "l": "IgZ immunoglobulin complex", "d": [], "t": []}], "preferred_name": "IgZ immunoglobulin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230594", "l": "Intranuclear mitochondrion", "d": [], "t": []}, {"i": "SNOMEDCT:88303009", "d": [], "t": []}], "preferred_name": "Intranuclear mitochondrion", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4691247", "l": "CRF1-DNF3 complex", "d": [], "t": []}], "preferred_name": "CRF1-DNF3 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4689933", "l": "ER to Golgi constitutive secretory pathway transport vesicle", "d": [], "t": []}], "preferred_name": "ER to Golgi constitutive secretory pathway transport vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4235116", "l": "DAPK1-calmodulin complex", "d": [], "t": []}], "preferred_name": "DAPK1-calmodulin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "86.296221842381144", "identifiers": [{"i": "GO:0048180", "l": "activin complex", "d": ["A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit."], "t": []}], "preferred_name": "activin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3546525", "l": "calcium ion-transporting ATPase complex", "d": [], "t": []}], "preferred_name": "calcium ion-transporting ATPase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167352", "l": "S-layer", "d": [], "t": []}], "preferred_name": "S-layer", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167510", "l": "sulfate adenylyltransferase complex (ATP)", "d": [], "t": []}], "preferred_name": "sulfate adenylyltransferase complex (ATP)", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521613", "l": "7p12-p11.2", "d": [], "t": []}, {"i": "NCIT:C13778", "l": "7p12-p11.2", "d": ["A chromosome band present on 7p"], "t": []}], "preferred_name": "7p12-p11.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "GO:0000314", "l": "organellar small ribosomal subunit", "d": ["The smaller of the two subunits of an organellar ribosome."], "t": []}], "preferred_name": "organellar small ribosomal subunit", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0038139", "l": "ERBB4-EGFR complex", "d": ["A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1)."], "t": []}], "preferred_name": "ERBB4-EGFR complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070692", "l": "CTDK-1 complex", "d": ["A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638)."], "t": []}], "preferred_name": "CTDK-1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044220", "l": "host cell perinuclear region of cytoplasm", "d": ["The host cell cytoplasm situated near, or occurring around, the host nucleus."], "t": []}], "preferred_name": "host cell perinuclear region of cytoplasm", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612793", "l": "integrin alpha4-beta7 complex", "d": [], "t": []}], "preferred_name": "integrin alpha4-beta7 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5451213", "l": "mannan polymerase I complex", "d": [], "t": []}], "preferred_name": "mannan polymerase I complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179466", "l": "Fibrillar component of intercellular matrix", "d": [], "t": []}], "preferred_name": "Fibrillar component of intercellular matrix", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0097449", "l": "astrocyte projection", "d": ["A prolongation or process extending from the soma of an astrocyte and wrapping around neurons."], "t": []}], "preferred_name": "astrocyte projection", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2678064", "l": "Hyaline inclusions", "d": [], "t": []}], "preferred_name": "Hyaline inclusions", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167048", "l": "electron transfer flavoprotein complex", "d": [], "t": []}], "preferred_name": "electron transfer flavoprotein complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166730", "l": "AP-2 adaptor complex location", "d": [], "t": []}], "preferred_name": "AP-2 adaptor complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0000344", "l": "plastid-encoded plastid RNA polymerase complex B", "d": ["A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation."], "t": []}], "preferred_name": "plastid-encoded plastid RNA polymerase complex B", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179987", "l": "Neck of spermatozoon", "d": [], "t": []}], "preferred_name": "Neck of spermatozoon", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0098027", "l": "virus tail, sheath", "d": ["The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm."], "t": []}], "preferred_name": "virus tail, sheath", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1515500", "l": "9p21-p22", "d": [], "t": []}, {"i": "NCIT:C26297", "l": "9p21-p22", "d": ["A chromosome band present on 9p"], "t": []}], "preferred_name": "9p21-p22", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1520395", "l": "11q21-q22", "d": [], "t": []}, {"i": "NCIT:C38356", "l": "11q21-q22", "d": ["A chromosome band present on 11q"], "t": []}], "preferred_name": "11q21-q22", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0046818", "l": "dense nuclear body", "d": ["A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously."], "t": []}], "preferred_name": "dense nuclear body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0035619", "l": "root hair tip", "d": ["The tip portion of an outgrowth of a root epidermal cell."], "t": []}], "preferred_name": "root hair tip", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1325608", "l": "actomyosin, myosin complex part", "d": [], "t": []}], "preferred_name": "actomyosin, myosin complex part", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0016613", "l": "vanadium-iron nitrogenase complex", "d": ["An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer."], "t": []}], "preferred_name": "vanadium-iron nitrogenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3272063", "l": "supraspliceosomal complex", "d": [], "t": []}], "preferred_name": "supraspliceosomal complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070030", "l": "alphav-beta1 integrin-osteopontin complex", "d": ["A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin."], "t": []}], "preferred_name": "alphav-beta1 integrin-osteopontin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1749487", "l": "nicotinic acetylcholine receptor location", "d": [], "t": []}], "preferred_name": "nicotinic acetylcholine receptor location", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754109", "l": "mammalian U2-type spliceosomal complex A", "d": [], "t": []}], "preferred_name": "mammalian U2-type spliceosomal complex A", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009375", "l": "ferredoxin hydrogenase complex", "d": ["An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances."], "t": []}], "preferred_name": "ferredoxin hydrogenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612463", "l": "spherical high-density lipoprotein particle", "d": [], "t": []}], "preferred_name": "spherical high-density lipoprotein particle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1520687", "l": "16p13.13-p13.12", "d": [], "t": []}, {"i": "NCIT:C29968", "l": "16p13.13-p13.12", "d": ["A chromosome band present on 16p"], "t": []}], "preferred_name": "16p13.13-p13.12", "taxa": []} {"type": "biolink:CellularComponent", "ic": "78.28002550197246", "identifiers": [{"i": "GO:0005871", "l": "kinesin complex", "d": ["Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work."], "t": []}], "preferred_name": "kinesin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0098855", "l": "HCN channel complex", "d": ["A cation ion channel with a preference for K+ over Na+ ions, which is activated by membrane hyperpolarization, and consists of a tetramer of HCN family members. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart."], "t": []}], "preferred_name": "HCN channel complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1520403", "l": "11q23.1-q23.3", "d": [], "t": []}, {"i": "NCIT:C29737", "l": "11q23.1-q23.3", "d": ["A chromosome band present on 11q"], "t": []}], "preferred_name": "11q23.1-q23.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690165", "l": "calcium:proton antiporter complex", "d": [], "t": []}], "preferred_name": "calcium:proton antiporter complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030661", "l": "chitosome membrane", "d": ["The lipid bilayer surrounding a chitosome."], "t": []}], "preferred_name": "chitosome membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009921", "l": "auxin efflux carrier complex", "d": ["The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell."], "t": []}], "preferred_name": "auxin efflux carrier complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C2346553", "l": "6q25.2-q26", "d": [], "t": []}, {"i": "NCIT:C68728", "l": "6q25.2-q26", "d": ["A chromosome band present on 6q"], "t": []}], "preferred_name": "6q25.2-q26", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0032177", "l": "cellular bud neck split septin rings", "d": ["Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. 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All subunits are essential for viability and are conserved from yeast to mammals, including humans."], "t": []}], "preferred_name": "rixosome complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0099092", "l": "postsynaptic density, intracellular component", "d": ["A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. 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"53.872936168863703", "identifiers": [{"i": "MESH:D002462", "l": "Cell Membrane", "d": [], "t": []}, {"i": "UMLS:C0007603", "l": "Plasma membrane", "d": [], "t": []}, {"i": "NCIT:C13735", "l": "Plasma Membrane", "d": ["The semipermeable membrane that encloses the cytoplasm of a cell."], "t": []}, {"i": "SNOMEDCT:53982002", "d": [], "t": []}], "preferred_name": "Cell Membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230781", "l": "Granular endoplasmic reticulum, cisternal lumen", "d": [], "t": []}, {"i": "SNOMEDCT:15914006", "d": [], "t": []}], "preferred_name": "Granular endoplasmic reticulum, cisternal lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2247585", "l": "isolation membrane", "d": [], "t": []}], "preferred_name": "isolation membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1180012", "l": "Lipid bilayer of wall of Golgi 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"d": [], "t": []}], "preferred_name": "phosphatase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156282", "l": "ascus epiplasm", "d": [], "t": []}], "preferred_name": "ascus epiplasm", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2753501", "l": "interleukin-27 complex", "d": [], "t": []}], "preferred_name": "interleukin-27 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0060104", "l": "surface coat of collagen and cuticulin-based cuticle extracellular matrix", "d": ["An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans."], "t": []}], "preferred_name": "surface coat of collagen and cuticulin-based cuticle extracellular matrix", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005723", "l": "alpha-heterochromatin", "d": ["A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization."], "t": []}], "preferred_name": "alpha-heterochromatin", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "UMLS:C1515469", "l": "8q24.12", "d": [], "t": []}, {"i": "NCIT:C13784", "l": "8q24.12", "d": ["A chromosome band present on 8q"], "t": []}], "preferred_name": "8q24.12", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0038059", "l": "IKKalpha-IKKalpha complex", "d": ["A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits."], "t": []}], "preferred_name": "IKKalpha-IKKalpha complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230823", "l": "Autolysosome containing recognizable cytoplasmic organelle", "d": [], "t": []}, {"i": "SNOMEDCT:51214005", "d": [], "t": []}], "preferred_name": "Autolysosome containing recognizable cytoplasmic organelle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0918262", "l": "plant cell wall", "d": [], "t": []}], "preferred_name": "plant cell wall", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097426", "l": "glial filament", "d": ["An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes."], "t": []}], "preferred_name": "glial filament", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3893250", "l": "trans face", "d": [], "t": []}], "preferred_name": "trans face", "taxa": []} {"type": "biolink:CellularComponent", "ic": "71.908409916284086", "identifiers": [{"i": "MESH:D008870", "l": "Microtubules", "d": [], "t": []}, {"i": "UMLS:C0026046", "l": "Microtubules", "d": [], "t": []}, {"i": "NCIT:C13256", "l": "Microtubule", "d": ["Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. 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(from LocusLink)"], "t": []}], "preferred_name": "Microtubules", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1520580", "l": "14q11.2-q12", "d": [], "t": []}, {"i": "NCIT:C13905", "l": "14q11.2-q12", "d": ["A chromosome band present on 14q"], "t": []}], "preferred_name": "14q11.2-q12", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0000113", "l": "nucleotide-excision repair factor 4 complex", "d": ["One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. 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Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules."], "t": []}], "preferred_name": "conoid", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4318503", "l": "ciliary vesicle", "d": [], "t": []}], "preferred_name": "ciliary vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5450875", "l": "ribosomal DNA heterochromatin of cell nucleus", "d": [], "t": []}], "preferred_name": "ribosomal DNA heterochromatin of cell nucleus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896441", "l": "C/EBPalpha complex", "d": [], "t": []}], "preferred_name": "C/EBPalpha complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523002", "l": "chromatophore ribulose bisphosphate carboxylase complex", "d": [], "t": []}], "preferred_name": "chromatophore ribulose bisphosphate carboxylase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612576", "l": "Golgi stack lumen", "d": [], "t": []}], "preferred_name": "Golgi stack lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4235042", "l": "SNF1/AMPK protein kinase complex", "d": [], "t": []}], "preferred_name": "SNF1/AMPK protein kinase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070764", "l": "gamma-secretase-Delta1 complex", "d": ["A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex."], "t": []}], "preferred_name": "gamma-secretase-Delta1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0032449", "l": "CBM complex", "d": ["A protein complex comprising Bcl10, MALT1 and a CARD domain-containing protein (CARD9, CARD10 or CARD11); plays a role in signal transduction during NF-kappaB activation."], "t": []}], "preferred_name": "CBM complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009355", "l": "DNA polymerase V complex", "d": ["A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis."], "t": []}], "preferred_name": "DNA polymerase V complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "GO:1990265", "l": "platelet-derived growth factor complex", "d": ["A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. 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In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD)."], "t": []}], "preferred_name": "platelet-derived growth factor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5185139", "l": "Viral inclusion bodies | XXX | Cytology", "d": [], "t": []}], "preferred_name": "Viral inclusion bodies | XXX | Cytology", "taxa": []} {"type": "biolink:CellularComponent", "ic": "52.804021074947293", "identifiers": [{"i": "UMLS:C0175996", "l": "Protoplasm", "d": [], "t": []}, {"i": "NCIT:C43596", "l": "Protoplasm", "d": ["The organized colloidal complex of organic and inorganic substances (as proteins and water) that constitutes the living nucleus, cytoplasm, plastids, and mitochondria of the cell. It is composed mainly of nucleic acids, proteins, lipids, carbohydrates, and inorganic salts."], "t": []}], "preferred_name": "Protoplasm", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071186", "l": "protocadherin-alpha-v4-protocadherin-gamma-b2 complex", "d": ["A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane."], "t": []}], "preferred_name": "protocadherin-alpha-v4-protocadherin-gamma-b2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0043078", "l": "polar nucleus", "d": ["Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus."], "t": []}], "preferred_name": "polar nucleus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3889573", "l": "peptidase inhibitor complex location", "d": [], "t": []}], "preferred_name": "peptidase inhibitor complex location", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005831", "l": "steroid hormone aporeceptor complex", "d": ["A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand."], "t": []}], "preferred_name": "steroid hormone aporeceptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0598592", "l": "heterochromosome", "d": [], "t": []}], "preferred_name": "heterochromosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070117", "l": "organellar chromatophore thylakoid lumen", "d": ["The volume enclosed by an organellar chromatophore thylakoid membrane."], "t": []}], "preferred_name": "organellar chromatophore thylakoid lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0062048", "l": "lymphotoxin complex", "d": ["A homo- or heterotrimeric protein containing complex consisting of alpha and beta lymphotoxin subunits in different stoichiometric combinations."], "t": []}], "preferred_name": "lymphotoxin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166731", "l": "clathrin coat of synaptic vesicle", "d": [], "t": []}], "preferred_name": "clathrin coat of synaptic vesicle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0045170", "l": "spectrosome", "d": ["A germline specific spherical organelle, rich in membrane skeletal proteins. 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This complex is evolutionarily conserved except that the number of homoprotomers per complex varies."], "t": []}], "preferred_name": "glutamate dehydrogenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5450970", "l": "PS1 complex", "d": [], "t": []}], "preferred_name": "PS1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031095", "l": "platelet dense tubular network membrane", "d": ["The lipid bilayer surrounding the platelet dense tubular network."], "t": []}], "preferred_name": "platelet dense tubular network membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3888045", "l": "PcG protein complex", "d": [], "t": []}], "preferred_name": "PcG protein complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071119", "l": "alpha7-beta1 integrin-nicotinamide riboside kinase complex", "d": ["A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP)."], "t": []}], "preferred_name": "alpha7-beta1 integrin-nicotinamide riboside kinase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5815106", "l": "iRhom2/ADAM17 sheddase complex", "d": [], "t": []}], "preferred_name": "iRhom2/ADAM17 sheddase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4328033", "l": "plasma membrane bounded cell projection", "d": [], "t": []}], "preferred_name": "plasma membrane bounded cell projection", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990588", "l": "FtsBL complex", "d": ["A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. 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The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex."], "t": []}], "preferred_name": "sarcoglycan complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5450971", "l": "PS2 complex", "d": [], "t": []}], "preferred_name": "PS2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "78.28002550197246", "identifiers": [{"i": "UMLS:C1520355", "l": "11p11.2", "d": [], "t": []}, {"i": "NCIT:C13570", "l": "11p11.2", "d": ["A chromosome band present on 11p"], "t": []}], "preferred_name": "11p11.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230837", "l": "Adhesion specialization between microbodies", "d": [], "t": []}, {"i": "SNOMEDCT:52676006", "d": [], "t": []}], "preferred_name": "Adhesion specialization between microbodies", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137404", "l": "phenyloplast", "d": [], "t": []}], "preferred_name": "phenyloplast", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824471", "l": "PDGF-AB dimer", "d": [], "t": []}], "preferred_name": "PDGF-AB dimer", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754335", "l": "alpha9-beta1 integrin-ADAM8 complex", "d": [], "t": []}], "preferred_name": "alpha9-beta1 integrin-ADAM8 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1520583", "l": "14q13.1", "d": [], "t": []}, {"i": "NCIT:C24947", "l": "14q13.1", "d": ["A chromosome band present on 14q"], "t": []}], "preferred_name": "14q13.1", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179957", "l": "Layer of plasma membrane", "d": [], "t": []}], "preferred_name": "Layer of plasma membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990941", "l": "mitotic spindle kinetochore microtubule", "d": ["Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation."], "t": []}], "preferred_name": "mitotic spindle kinetochore microtubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2332089", "l": "Cytoplasm of reticular cell", "d": [], "t": []}], "preferred_name": "Cytoplasm of reticular cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0097513", "l": "myosin II filament", "d": ["A bipolar filament composed of myosin II molecules."], "t": []}], "preferred_name": "myosin II filament", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612416", "l": "Sec secretion complex", "d": [], "t": []}], "preferred_name": "Sec secretion complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0000164", "l": "protein phosphatase type 1 complex", "d": ["A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity."], "t": []}], "preferred_name": "protein phosphatase type 1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0042581", "l": "specific granule", "d": ["Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. 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LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. 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In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell."], "t": []}], "preferred_name": "polar tube", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1905720", "l": "cytoplasmic microtubule bundle", "d": ["Any microtubule bundle that is part of a cytoplasm."], "t": []}], "preferred_name": "cytoplasmic microtubule bundle", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0009508", "l": "plastid chromosome", "d": ["A circular DNA molecule containing plastid encoded genes."], "t": []}], "preferred_name": "plastid chromosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3893620", "l": "SCF-Saf1/Pof9 ubiquitin ligase complex", "d": [], "t": []}], "preferred_name": "SCF-Saf1/Pof9 ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1520186", "l": "Xq22", "d": [], "t": []}, {"i": "NCIT:C25142", "l": "Xq22", "d": ["A chromosome band present on Xq"], "t": []}], "preferred_name": "Xq22", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070082", "l": "clathrin-sculpted monoamine transport vesicle lumen", "d": ["The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle."], "t": []}], "preferred_name": "clathrin-sculpted monoamine transport vesicle lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156028", "l": "SAGA DUBm complex", "d": [], "t": []}], "preferred_name": "SAGA DUBm complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071133", "l": "alpha9-beta1 integrin-ADAM8 complex", "d": ["A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8."], "t": []}], "preferred_name": "alpha9-beta1 integrin-ADAM8 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0010170", "l": "glucose-1-phosphate adenylyltransferase complex", "d": ["Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. 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This complex includes the acetyltransferases GCN5/KAT2A or PCAF/KAT2B, several proteins of the ADA, SGF and SPT families, and several TBP-associate proteins (TAFs)."], "t": []}], "preferred_name": "SAGA-type complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612805", "l": "integrin alpha7-beta1 complex", "d": [], "t": []}], "preferred_name": "integrin alpha7-beta1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754379", "l": "MAML2-RBP-Jkappa-ICN3 complex", "d": [], "t": []}], "preferred_name": "MAML2-RBP-Jkappa-ICN3 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3893895", "l": "potassium:proton antiporter complex", "d": [], "t": []}], "preferred_name": "potassium:proton antiporter complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230709", "l": "CYTOPLASMIC FILAMENTS, TUBULES, CENTRIOLES AND ASSOCIATED STRUCTURES", "d": [], "t": []}], "preferred_name": "CYTOPLASMIC FILAMENTS, TUBULES, CENTRIOLES AND ASSOCIATED STRUCTURES", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1520483", "l": "12pter-p12", "d": [], "t": []}, {"i": "NCIT:C14013", "l": "12pter-p12", "d": ["A chromosome band present on 12p"], "t": []}], "preferred_name": "12pter-p12", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D022222", "l": "Chromosomes, Artificial, Human", "d": [], "t": []}], "preferred_name": "Chromosomes, Artificial, Human", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690297", "l": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer", "d": [], "t": []}], "preferred_name": "potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 tetramer", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031838", "l": "haptoglobin-hemoglobin complex", "d": ["A protein complex formed by the stable binding of a haptoglobin to hemoglobin."], "t": []}], "preferred_name": "haptoglobin-hemoglobin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0333900", "l": "Perinuclear halo", "d": [], "t": []}, {"i": "SNOMEDCT:59145000", "d": [], "t": []}], "preferred_name": "Perinuclear halo", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "UMLS:C2825759", "l": "3p22.2", "d": [], "t": []}, {"i": "NCIT:C81841", "l": "3p22.2", "d": ["A chromosome band present on 3p."], "t": []}], "preferred_name": "3p22.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0036062", "l": "presynaptic periactive zone", "d": ["A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development."], "t": []}], "preferred_name": "presynaptic periactive zone", "taxa": []} {"type": "biolink:CellularComponent", "ic": "69.920378237959397", "identifiers": [{"i": "GO:0005902", "l": "microvillus", "d": ["Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. 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This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs."], "t": []}], "preferred_name": "U12-type catalytic step 1 spliceosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070118", "l": "organellar chromatophore thylakoid membrane", "d": ["The lipid bilayer membrane of any thylakoid within an organellar chromatophore."], "t": []}], "preferred_name": "organellar chromatophore thylakoid membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3546552", "l": "primary cell wall cellulose synthase complex", "d": [], "t": []}], "preferred_name": "primary cell wall cellulose synthase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0042385", "l": "myosin III complex", "d": ["A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain."], "t": []}], "preferred_name": "myosin III complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005943", "l": "phosphatidylinositol 3-kinase complex, class IA", "d": ["A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways."], "t": []}], "preferred_name": "phosphatidylinositol 3-kinase complex, class IA", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0002944", "l": "cyclin K-CDK12 complex", "d": ["A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. 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null, "identifiers": [{"i": "UMLS:C3546236", "l": "MVB-tubule complex", "d": [], "t": []}], "preferred_name": "MVB-tubule complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167224", "l": "histamine-gated chloride channel complex", "d": [], "t": []}], "preferred_name": "histamine-gated chloride channel complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2263091", "l": "cellular bud neck", "d": [], "t": []}], "preferred_name": "cellular bud neck", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C2697589", "l": "Xpter-p22.32", "d": [], "t": []}, {"i": "NCIT:C75398", "l": "Xpter-p22.32", "d": ["A chromosome band present on Xp."], "t": []}], "preferred_name": "Xpter-p22.32", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005592", "l": "collagen type XI trimer", "d": ["A collagen heterotrimer 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Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein."], "t": []}], "preferred_name": "Wnt signalosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1521203", "l": "2q12.3", "d": [], "t": []}, {"i": "NCIT:C13909", "l": "2q12.3", "d": ["A chromosome band present on 2q"], "t": []}], "preferred_name": "2q12.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009338", "l": "exodeoxyribonuclease V complex", "d": ["An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. 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Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode."], "t": []}], "preferred_name": "lateral loop", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824544", "l": "Bfa1-Bub2 complex", "d": [], "t": []}], "preferred_name": "Bfa1-Bub2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1513115", "l": "Membrane of Crista", "d": [], "t": []}, {"i": "NCIT:C33078", "l": "Membrane of Crista", "d": ["The part of the inner mitochondrial membrane that folds inward to enclose the cristae."], "t": []}], "preferred_name": "Membrane of Crista", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D054974", "l": "Costameres", "d": [], "t": []}], "preferred_name": "Costameres", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D009469", "l": "Neuromuscular Junction", "d": [], "t": []}, {"i": "UMLS:C0027869", "l": "Neuromuscular Junction", "d": [], "t": []}], "preferred_name": "Neuromuscular Junction", "taxa": []} {"type": "biolink:CellularComponent", "ic": "85.520017001314969", "identifiers": [{"i": "UMLS:C1520183", "l": "Xq13.1", "d": [], "t": []}, {"i": "NCIT:C13779", "l": "Xq13.1", "d": ["A chromosome band present on Xq"], "t": []}], "preferred_name": "Xq13.1", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030288", "l": "outer membrane-bounded periplasmic space", "d": ["The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. 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The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor."], "t": []}], "preferred_name": "CD95 death-inducing signaling complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0099182", "l": "presynaptic intermediate filament cytoskeleton", "d": ["The intermediate filament cytoskeleton that is part of a presynapse."], "t": []}], "preferred_name": "presynaptic intermediate filament cytoskeleton", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179089", "l": "Spiral filament of axoneme of cilium", "d": [], "t": []}], "preferred_name": "Spiral filament of axoneme of cilium", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4323160", "l": "Fibrous sheath of tail of sperm cell", "d": [], "t": []}], "preferred_name": "Fibrous sheath of tail of sperm cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521459", "l": "5p15.1-p14", "d": [], "t": []}, {"i": "NCIT:C14046", "l": "5p15.1-p14", "d": ["A chromosome band present on 5p"], "t": []}], "preferred_name": "5p15.1-p14", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2755837", "l": "flagellar basal body", "d": [], "t": []}], "preferred_name": "flagellar basal body", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230528", "l": "Interphase nucleus", "d": [], "t": []}, {"i": "SNOMEDCT:83778003", "d": [], "t": []}], "preferred_name": "Interphase nucleus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1817598", "l": "cellulose synthase complex", "d": [], "t": []}], "preferred_name": "cellulose synthase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1521318", "l": "3q24-q28", "d": [], "t": []}, {"i": "NCIT:C13510", "l": "3q24-q28", "d": ["A chromosome band present on 3q"], "t": []}], "preferred_name": "3q24-q28", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005621", "l": "cellular bud scar", "d": ["Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age."], "t": []}], "preferred_name": "cellular bud scar", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120216", "l": "matrilin complex", "d": ["A cartilage extracellular matrix complex that mediates interactions between major components of the extracellular matrix such as collagens and proteoglycans and contributes to their fibrillar network. 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In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism."], "t": []}], "preferred_name": "Dsc E3 ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821135", "l": "ciliary necklace", "d": [], "t": []}], "preferred_name": "ciliary necklace", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230941", "l": "Granular inclusion, prokaryotic", "d": [], "t": []}, {"i": "SNOMEDCT:64076009", "d": [], "t": []}], "preferred_name": "Granular inclusion, prokaryotic", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D048631", "l": "Micronucleus, Germline", "d": [], "t": []}, {"i": "UMLS:C1449863", "l": "Micronucleus, Germline", "d": [], "t": []}], "preferred_name": "Micronucleus, Germline", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1520486", "l": "12q11-q14", "d": [], "t": []}, {"i": "NCIT:C13982", "l": "12q11-q14", "d": ["A chromosome band present on 12q"], "t": []}], "preferred_name": "12q11-q14", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0120217", "l": "DNA gyrase complex", "d": ["A bacterial type IIA topoisomerase that is unique in its function of introducing negative supercoils into DNA at the expense of ATP hydrolysis and is also capable of relaxing positive supercoils, an activity shared with topoisomerase IV. Typically, it is composed of two copies each of an A subunit (GyrA) and a B subunit (GyrB)."], "t": []}], "preferred_name": "DNA gyrase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4323161", "l": "Anaphase cell nucleus", "d": [], "t": []}], "preferred_name": "Anaphase cell nucleus", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1902501", "l": "lysosomal HOPS complex", "d": ["Any HOPS complex that is part of a lysosomal membrane."], "t": []}], "preferred_name": "lysosomal HOPS complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "UMLS:C1521629", "l": "7p21.3", "d": [], "t": []}, {"i": "NCIT:C13895", "l": "7p21.3", "d": ["A chromosome band present on 7p"], "t": []}], "preferred_name": "7p21.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "MESH:D022181", "l": "COP-Coated Vesicles", "d": [], "t": []}, {"i": "UMLS:C0887886", "l": "COP-Coated Vesicles", "d": [], "t": []}], "preferred_name": "COP-Coated Vesicles", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167092", "l": "RSC-type complex", "d": [], "t": []}], "preferred_name": "RSC-type complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2752514", "l": "host cell perinuclear region of cytoplasm", "d": [], "t": []}], "preferred_name": "host cell perinuclear region of cytoplasm", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0005672", "l": "transcription factor TFIIA complex", "d": ["A component of the transcription machinery of RNA Polymerase II. 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It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. 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They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. 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The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors."], "t": []}], "preferred_name": "interleukin-10 receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.95209094877535", "identifiers": [{"i": "UMLS:C1520382", "l": "11q13.1", "d": [], "t": []}, {"i": "NCIT:C13876", "l": "11q13.1", "d": ["A chromosome band present on 11q"], "t": []}], "preferred_name": "11q13.1", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1180001", "l": "Axodendritic synapse", "d": [], "t": []}, {"i": "NCIT:C32176", "l": "Axodendritic Synapse", "d": ["A synapse between the axon of one neuron and the dendrite of another neuron."], "t": []}], "preferred_name": "Axodendritic synapse", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3548418", "l": "CA3 pyramidal cell dendrite", "d": [], "t": []}], "preferred_name": "CA3 pyramidal cell dendrite", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230808", "l": "Fusiform vesicle, as in transitional epithelium", "d": [], "t": []}, {"i": "SNOMEDCT:57033003", "d": [], "t": []}], "preferred_name": "Fusiform vesicle, as in transitional epithelium", "taxa": []} {"type": "biolink:CellularComponent", "ic": "81.728295789841525", "identifiers": [{"i": "UMLS:C1520776", "l": "17q21.32", "d": [], "t": []}, {"i": "NCIT:C38943", "l": "17q21.32", "d": ["A chromosome band present on 17q"], "t": []}], "preferred_name": "17q21.32", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "UMLS:C1521204", "l": "2q14", "d": [], "t": []}, {"i": "NCIT:C13523", "l": "2q14", "d": ["A chromosome band present on 2q"], "t": []}], "preferred_name": "2q14", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3896280", "l": "mitotic spindle microtubule", "d": [], "t": []}], "preferred_name": "mitotic spindle microtubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030915", "l": "Smc5-Smc6 complex", "d": ["A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans."], "t": []}], "preferred_name": "Smc5-Smc6 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1180094", "l": "Wall of smooth endoplasmic reticulum tubule", "d": [], "t": []}], "preferred_name": "Wall of smooth endoplasmic reticulum tubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "GO:0035452", "l": "extrinsic component of plastid membrane", "d": ["The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region."], "t": []}], "preferred_name": "extrinsic component of plastid membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "UMLS:C1521555", "l": "6q12", "d": [], "t": []}, {"i": "NCIT:C25093", "l": "6q12", "d": ["A chromosome band present on 6q"], "t": []}], "preferred_name": "6q12", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0099400", "l": "caveola neck", "d": ["A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. 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Glycoproteins undergo their initial glycosylation within the cisternae."], "t": []}], "preferred_name": "rough endoplasmic reticulum", "taxa": []} {"type": "biolink:CellularComponent", "ic": "73.591176345487725", "identifiers": [{"i": "MESH:D012270", "l": "Ribosomes", "d": [], "t": []}, {"i": "UMLS:C0035553", "l": "Ribosomes", "d": [], "t": []}, {"i": "NCIT:C13274", "l": "Ribosome", "d": ["Ribosomes are small organelles composed of ribosomal RNA (rRNA) and 80 some different proteins. rRNA is synthesized in the nucleolus and the ribosomal subunits are assembled there from rRNA and imported cytoplasmic made proteins. Once assembled, the subunits pass through the nuclear pores to the cytoplasm where they take part in protein synthesis. Some ribosomes are free in the cytoplasm and can be recruited to a polyribosomal structure when a messenger RNA (mRNA) strand is to be translated into a cytoplasmic protein. Other ribosomes are attached to the endoplasmic reticulum where the protein is formed within the interior to the endoplasmic reticulum. These proteins are destined for secretion, storage or incorporation into membranes."], "t": []}, {"i": "SNOMEDCT:26761006", "d": [], "t": []}], "preferred_name": "Ribosomes", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3548427", "l": "mitotic spindle pole", "d": [], "t": []}], "preferred_name": "mitotic spindle pole", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0098861", "l": "actin filament bundle of filopodium", "d": ["A parallel bundle of actin filaments that is part of filopodium. 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Includes actin cytoskeleton-associated complexes."], "t": []}], "preferred_name": "actin cytoskeleton", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031003", "l": "actin tubule", "d": ["A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together."], "t": []}], "preferred_name": "actin tubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2327451", "l": "Plasma membrane of osteocyte", "d": [], "t": []}], "preferred_name": "Plasma membrane of osteocyte", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824542", "l": "Ire1 complex", "d": [], "t": []}], "preferred_name": "Ire1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2326432", "l": "Protoplasm of Type TG enteroendocrine cell", "d": [], "t": []}], "preferred_name": "Protoplasm of Type TG enteroendocrine 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"UMLS:C1167106", "l": "mRNA cleavage factor complex", "d": [], "t": []}], "preferred_name": "mRNA cleavage factor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0140715", "l": "serine-tRNA ligase complex", "d": ["A heterodimeric enzyme complex that catalyzes the ligation of serine to tRNA(Ser), forming L-seryl-tRNA(Ser)."], "t": []}], "preferred_name": "serine-tRNA ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690666", "l": "apicomedial cortex", "d": [], "t": []}], "preferred_name": "apicomedial cortex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C1521498", "l": "5q34-q35", "d": [], "t": []}, {"i": "NCIT:C25087", "l": "5q34-q35", "d": ["A chromosome band present on 5q"], "t": []}], "preferred_name": "5q34-q35", "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.624156395578254", "identifiers": [{"i": 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It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins."], "t": []}], "preferred_name": "perinuclear theca", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990665", "l": "AnxA2-p11 complex", "d": ["A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10)."], "t": []}], "preferred_name": "AnxA2-p11 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0002141", "l": "stereocilia ankle link", "d": ["A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia."], "t": []}], "preferred_name": "stereocilia ankle link", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0035525", "l": "NF-kappaB p50/p65 complex", "d": ["A heterodimer of NF-kappa B p50 and p65 subunits."], "t": []}], "preferred_name": "NF-kappaB p50/p65 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523842", "l": "dendritic shaft", "d": [], "t": []}], "preferred_name": "dendritic shaft", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "UMLS:C2346540", "l": "16q21-q22.3", "d": [], "t": []}, {"i": "NCIT:C73646", "l": "16q21-q22.3", "d": ["A chromosome band present on 16q"], "t": []}], "preferred_name": "16q21-q22.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0160169", "l": "T=21/pseudo21 icosahedral capsid", "d": ["The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=21 or pseudo T=21 symmetry."], "t": []}], "preferred_name": "T=21/pseudo21 icosahedral capsid", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031467", "l": "Cul7-RING ubiquitin ligase complex", "d": ["A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein."], "t": []}], "preferred_name": "Cul7-RING ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0035749", "l": "myelin sheath adaxonal region", "d": ["The region of the myelin sheath nearest to the axon."], "t": []}], "preferred_name": "myelin sheath adaxonal region", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2752470", "l": "host cell Golgi apparatus", "d": [], "t": []}], "preferred_name": "host cell Golgi apparatus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230533", "l": "Anaphase nucleus", "d": [], "t": []}, {"i": "SNOMEDCT:11219001", "d": [], "t": []}], "preferred_name": "Anaphase nucleus", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137268", "l": "ATG2-ATG18 complex", "d": [], "t": []}], "preferred_name": "ATG2-ATG18 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070721", "l": "ISGF3 complex", "d": ["A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein."], "t": []}], "preferred_name": "ISGF3 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "UMLS:C1520190", "l": "Xq22.2", "d": [], "t": []}, {"i": "NCIT:C28560", "l": "Xq22.2", "d": ["A chromosome band present on Xq"], "t": []}], "preferred_name": "Xq22.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1521176", "l": "2p13.2", "d": [], "t": []}, {"i": "NCIT:C26069", "l": "2p13.2", "d": ["A chromosome band present on 2p"], "t": []}], "preferred_name": "2p13.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2753376", "l": "Shc-Grb2-Sos complex", "d": [], "t": []}], "preferred_name": "Shc-Grb2-Sos complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4234985", "l": "CMA receptor complex", "d": [], "t": []}], "preferred_name": "CMA receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821107", "l": "myosin II filament", "d": [], "t": []}], "preferred_name": "myosin II filament", "taxa": []} {"type": "biolink:CellularComponent", "ic": "83.096665005650948", "identifiers": [{"i": "GO:0005838", "l": "proteasome regulatory particle", "d": ["A multisubunit complex, which caps one or both ends of the proteasome core complex. 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RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex."], "t": []}], "preferred_name": "box H/ACA RNP complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030700", "l": "glycine reductase complex", "d": ["Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C."], "t": []}], "preferred_name": "glycine reductase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0019822", "l": "P4 peroxisome", "d": ["A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content."], "t": []}], "preferred_name": "P4 peroxisome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2613438", "l": "microtubule organizing center attachment site", "d": [], "t": []}], "preferred_name": "microtubule organizing center attachment site", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:1990121", "l": "H-NS complex", "d": ["A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA."], "t": []}], "preferred_name": "H-NS complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031476", "l": "myosin VI complex", "d": ["A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments."], "t": []}], "preferred_name": "myosin VI complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:1990233", "l": "intramolecular phosphotransferase complex", "d": ["A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule."], "t": []}], "preferred_name": "intramolecular phosphotransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031483", "l": "myosin XIII complex", "d": ["A myosin complex containing one or more class XIII myosin heavy chains and associated light chains."], "t": []}], "preferred_name": "myosin XIII complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167313", "l": "ubiquitin ligase complex", "d": [], "t": []}], "preferred_name": "ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0000446", "l": "nucleoplasmic THO complex", "d": ["The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits."], "t": []}], "preferred_name": "nucleoplasmic THO complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "73.01776055881858", "identifiers": [{"i": "GO:0033648", "l": "host intracellular membrane-bounded organelle", "d": ["Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction."], "t": []}], "preferred_name": "host intracellular membrane-bounded organelle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2322725", "l": "Cytoplasm of epithelial cell of collecting duct of renal tubule", "d": [], "t": []}], "preferred_name": "Cytoplasm of epithelial cell of collecting duct of renal tubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": "86.296221842381144", "identifiers": [{"i": "GO:0005796", "l": "Golgi lumen", "d": ["The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks."], "t": []}], "preferred_name": "Golgi lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137278", "l": "Cdc24p-Far1p-Gbetagamma complex", "d": [], "t": []}], "preferred_name": "Cdc24p-Far1p-Gbetagamma complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097182", "l": "protein C inhibitor-coagulation factor Xa complex", "d": ["A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa."], "t": []}], "preferred_name": "protein C inhibitor-coagulation factor Xa complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "82.608284260268121", "identifiers": [{"i": "GO:0031501", "l": "mannosyltransferase complex", "d": ["A complex that possesses mannosyltransferase activity."], "t": []}], "preferred_name": "mannosyltransferase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167441", "l": "DNA polymerase V complex", "d": [], "t": []}], "preferred_name": "DNA polymerase V complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "UMLS:C1520944", "l": "1p22-p21", "d": [], "t": []}, {"i": "NCIT:C13814", "l": "1p22-p21", "d": ["A chromosome band present on 1p"], "t": []}], "preferred_name": "1p22-p21", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4327158", "l": "BORC complex", "d": [], "t": []}], "preferred_name": "BORC complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0043505", "l": "CENP-A containing nucleosome", "d": ["A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3)."], "t": []}], "preferred_name": "CENP-A containing nucleosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2335005", "l": "Plasma membrane of reticular cell", "d": [], "t": []}], "preferred_name": "Plasma membrane of reticular cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824380", "l": "FMN reductase complex", "d": [], "t": []}], "preferred_name": "FMN reductase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2335035", "l": "Set of reticular nuclei of pontile tegmentum", "d": [], "t": []}], "preferred_name": "Set of reticular nuclei of pontile tegmentum", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754965", "l": "surface IgG2c", "d": [], "t": []}], "preferred_name": "surface IgG2c", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0033065", "l": "Rad51C-XRCC3 complex", "d": ["A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof."], "t": []}], "preferred_name": "Rad51C-XRCC3 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2247240", "l": "SUMO-targeted ubiquitin ligase complex", "d": [], "t": []}], "preferred_name": "SUMO-targeted ubiquitin ligase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034206", "l": "enhanceosome", "d": ["A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation."], "t": []}], "preferred_name": "enhanceosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0005872", "l": "minus-end kinesin complex", "d": ["Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule."], "t": []}], "preferred_name": "minus-end kinesin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137533", "l": "cone telodendria", "d": [], "t": []}], "preferred_name": "cone telodendria", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "UMLS:C1521282", "l": "3p21-p14", "d": [], "t": []}, {"i": "NCIT:C13631", "l": "3p21-p14", "d": ["A chromosome band present on 3p"], "t": []}], "preferred_name": "3p21-p14", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0048046", "l": "apoplast", "d": ["The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it."], "t": []}], "preferred_name": "apoplast", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230717", "l": "H zone", "d": [], "t": []}, {"i": "SNOMEDCT:25771000", "d": [], "t": []}], "preferred_name": "H zone", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C0682566", "l": "Sarcoplasm", "d": [], "t": []}, {"i": "NCIT:C33513", "l": "Sarcoplasm", "d": ["The cytoplasm of striated muscle fibre."], "t": []}], "preferred_name": "Sarcoplasm", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1523558", "l": "BLOC-2 complex", "d": [], "t": []}], "preferred_name": "BLOC-2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1819334", "l": "stereocilium bundle", "d": [], "t": []}], "preferred_name": "stereocilium bundle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179052", "l": "Neck of cone cell", "d": [], "t": []}], "preferred_name": "Neck of cone cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "UMLS:C1179905", "l": "Cavity of peroxisome", "d": [], "t": []}, {"i": "NCIT:C33018", "l": "Lumen of the Peroxisome", "d": ["The area within the membrane of a peroxisome."], "t": []}], "preferred_name": "Cavity of peroxisome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0060203", "l": "clathrin-sculpted glutamate transport vesicle membrane", "d": ["The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle."], "t": []}], "preferred_name": "clathrin-sculpted glutamate transport vesicle membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "UMLS:C1512540", "l": "Hydrophobic Portion of the Plasma Membrane", "d": [], "t": []}, {"i": "NCIT:C32749", "l": "Hydrophobic Portion of the Plasma Membrane", "d": ["The inner part of the lipid bilayer that is comprised of the hydrophobic tails of the lipid components and the membrane spanning domains of transmembrane proteins."], "t": []}], "preferred_name": "Hydrophobic Portion of the Plasma Membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": "84.825678110700707", "identifiers": [{"i": "UMLS:C1521107", "l": "22q11.23", "d": [], "t": []}, {"i": "NCIT:C13886", "l": "22q11.23", "d": ["A chromosome band present on 22q"], "t": []}], "preferred_name": "22q11.23", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "UMLS:C1521698", "l": "8p12-p11.2", "d": [], "t": []}, {"i": "NCIT:C13774", "l": "8p12-p11.2", "d": ["A chromosome band present on 8p"], "t": []}], "preferred_name": "8p12-p11.2", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2333907", "l": "Plasma membrane of monocyte", "d": [], "t": []}], "preferred_name": "Plasma membrane of monocyte", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166607", "l": "cellular_component", "d": [], "t": []}], "preferred_name": "cellular_component", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0009424", "l": "bacterial-type flagellum hook", "d": ["The portion of the bacterial-type flagellum that connects the filament to the basal body."], "t": []}], "preferred_name": "bacterial-type flagellum hook", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179143", "l": "Sarcoplasmic reticulum of cardiac muscle cell", "d": [], "t": []}], "preferred_name": "Sarcoplasmic reticulum of cardiac muscle cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612815", "l": "integrin alphav-beta1 complex", "d": [], "t": []}], "preferred_name": "integrin alphav-beta1 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990666", "l": "PCSK9-LDLR complex", "d": ["A protein complex consisting of the serine protease PCSK9 (proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway."], "t": []}], "preferred_name": "PCSK9-LDLR complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031019", "l": "mitochondrial mRNA editing complex", "d": ["An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates."], "t": []}], "preferred_name": "mitochondrial mRNA editing complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167323", "l": "proton-transporting two-sector ATPase complex", "d": [], "t": []}], "preferred_name": "proton-transporting two-sector ATPase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167132", "l": "core-binding factor complex", "d": [], "t": []}], "preferred_name": "core-binding factor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3824386", "l": "taurine dioxygenase complex", "d": [], "t": []}], "preferred_name": "taurine dioxygenase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "69.329822976705557", "identifiers": [{"i": "MESH:D002883", "l": "Chromosomes, Human, Pair 14", "d": [], "t": []}, {"i": "UMLS:C0008656", "l": "Chromosomes, Human, Pair 14", "d": [], "t": []}, {"i": "NCIT:C13209", "l": "Human Chromosome 14", "d": ["The designation for each member of the fourteenth largest human autosomal chromosome pair. Chromosome 14 spans about 105 million base pairs and represents between 3 and 3.5% of the total DNA in normal diploid cells."], "t": []}, {"i": "SNOMEDCT:66933007", "d": [], "t": []}], "preferred_name": "Chromosomes, Human, Pair 14", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0031601", "l": "nuclear proteasome core complex", "d": ["The core complex of a proteasome located in the nucleus of a cell."], "t": []}], "preferred_name": "nuclear proteasome core complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "89.393604163240326", "identifiers": [{"i": "UMLS:C1520264", "l": "10p15-p14", "d": [], "t": []}, {"i": "NCIT:C14122", "l": "10p15-p14", "d": ["A chromosome band present on 10p"], "t": []}], "preferred_name": "10p15-p14", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1167080", "l": "granular component", "d": [], "t": []}], "preferred_name": "granular component", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0034422", "l": "aleurone grain lumen", "d": ["The volume enclosed by the membrane of an aleurone grain."], "t": []}], "preferred_name": "aleurone grain lumen", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C0230512", "l": "Apical region of polarized cell", "d": [], "t": []}, {"i": "SNOMEDCT:14906008", "d": [], "t": []}], "preferred_name": "Apical region of polarized cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2339944", "l": "Protoplasm of Type EC2 enteroendocrine cell", "d": [], "t": []}], "preferred_name": "Protoplasm of Type EC2 enteroendocrine cell", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3159005", "l": "meiotic recombination initiation complex", "d": [], "t": []}], "preferred_name": "meiotic recombination initiation complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3156650", "l": "box H/ACA scaRNP complex", "d": [], "t": []}], "preferred_name": "box H/ACA scaRNP complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1179119", "l": "Annulate lamella pore complex", "d": [], "t": []}], "preferred_name": "Annulate lamella pore complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071756", "l": "pentameric IgM immunoglobulin complex", "d": ["A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide."], "t": []}], "preferred_name": "pentameric IgM immunoglobulin complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1990453", "l": "nucleosome disassembly/reassembly complex", "d": ["A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex."], "t": []}], "preferred_name": "nucleosome disassembly/reassembly complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0140512", "l": "mitotic nuclear bridge midzone", "d": ["The central region of a mitotic nuclear bridge, distal to the main portions of the daughter nuclei."], "t": []}], "preferred_name": "mitotic nuclear bridge midzone", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:1905202", "l": "methylcrotonoyl-CoA carboxylase complex", "d": ["A protein complex capable of methylcrotonoyl-CoA carboxylase activity. In mammals, it is a mitochondrial complex comprising a dodecamer of 6 alpha and 6 beta subunits: MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation; MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA."], "t": []}], "preferred_name": "methylcrotonoyl-CoA carboxylase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0031560", "l": "cellular bud neck polarisome", "d": ["Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis."], "t": []}], "preferred_name": "cellular bud neck polarisome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0044300", "l": "cerebellar mossy fiber", "d": ["An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. 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The enlargements of the rosettes give the axons a mossy-looking appearance in Golgi stained preparations."], "t": []}], "preferred_name": "cerebellar mossy fiber", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0000438", "l": "core TFIIH complex portion of holo TFIIH complex", "d": ["The core TFIIH complex when it is part of the general transcription factor TFIIH."], "t": []}], "preferred_name": "core TFIIH complex portion of holo TFIIH complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5450982", "l": "GTPase-containing complex for Gap1p sorting in the endosome", "d": [], "t": []}], "preferred_name": "GTPase-containing complex for Gap1p sorting in the endosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "82.153612663897817", "identifiers": [{"i": "GO:0005912", "l": "adherens junction", "d": ["A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules."], "t": []}], "preferred_name": "adherens junction", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3159062", "l": "Seh1-associated complex", "d": [], "t": []}], "preferred_name": "Seh1-associated complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3823015", "l": "left ventral basal body", "d": [], "t": []}], "preferred_name": "left ventral basal body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071056", "l": "alpha9-beta1 integrin-ADAM15 complex", "d": ["A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15."], "t": []}], "preferred_name": "alpha9-beta1 integrin-ADAM15 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "80.95209094877535", "identifiers": [{"i": "GO:0097650", "l": "B axonemal microtubule", "d": ["An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet."], "t": []}], "preferred_name": "B axonemal microtubule", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0033179", "l": "proton-transporting V-type ATPase, V0 domain", "d": ["A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. 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The complex functions primarily as an activating receptor for IgG."], "t": []}], "preferred_name": "Fc-gamma receptor III complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0005822", "l": "inner plaque of spindle pole body", "d": ["One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus."], "t": []}], "preferred_name": "inner plaque of spindle pole body", "taxa": []} {"type": "biolink:CellularComponent", "ic": "79.056230343038635", "identifiers": [{"i": "GO:0044304", "l": "main axon", "d": ["The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites."], "t": []}], "preferred_name": "main axon", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0120100", "l": "bacterial-type flagellum motor", "d": ["A transmembrane complex embedded in the cytoplasmic membrane which is the motor force, or torque, generator of the bacterial-type flagellum. 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Isoamylases in animals are localized in the extracellular space."], "t": []}], "preferred_name": "extracellular isoamylase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1166869", "l": "hydrogenosome", "d": [], "t": []}], "preferred_name": "hydrogenosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "88.192082448117873", "identifiers": [{"i": "UMLS:C1521458", "l": "5p13.3", "d": [], "t": []}, {"i": "NCIT:C13831", "l": "5p13.3", "d": ["A chromosome band present on 5p"], "t": []}], "preferred_name": "5p13.3", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2610712", "l": "syntaxin-6-syntaxin-16-Vti1a complex", "d": [], "t": []}], "preferred_name": "syntaxin-6-syntaxin-16-Vti1a complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612911", "l": "cytosolic aryl hydrocarbon receptor complex", "d": [], "t": []}], "preferred_name": "cytosolic aryl hydrocarbon receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0009705", "l": "plant-type vacuole membrane", "d": ["The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. 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This stable complex formation is thought to prevent CD74 degradation by caspases."], "t": []}], "preferred_name": "NOS2-CD74 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754222", "l": "alpha6-beta1 integrin-CD151 complex", "d": [], "t": []}], "preferred_name": "alpha6-beta1 integrin-CD151 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2262721", "l": "ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing", "d": [], "t": []}], "preferred_name": "ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0097418", "l": "neurofibrillary tangle", "d": ["Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. 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The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres."], "t": []}], "preferred_name": "T=3 icosahedral viral capsid", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2752287", "l": "pre-B cell receptor complex", "d": [], "t": []}], "preferred_name": "pre-B cell receptor complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4690094", "l": "leading edge of dendritic growth cone", "d": [], "t": []}], "preferred_name": "leading edge of dendritic growth cone", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4761336", "l": "photoreceptor distal connecting cilium", "d": [], "t": []}], "preferred_name": "photoreceptor distal connecting cilium", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2612461", "l": "high-density lipoprotein particle", "d": [], "t": []}], "preferred_name": "high-density lipoprotein particle", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5451578", "l": "histone H3-containing nucleosome", "d": [], "t": []}], "preferred_name": "histone H3-containing nucleosome", "taxa": []} {"type": "biolink:CellularComponent", "ic": "95.432073947460381", "identifiers": [{"i": "GO:0098567", "l": "periplasmic side of plasma membrane", "d": ["The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface."], "t": []}], "preferred_name": "periplasmic side of plasma membrane", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2247868", "l": "PtdIns-3-kinase complex I", "d": [], "t": []}], "preferred_name": "PtdIns-3-kinase complex I", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2247091", "l": "host cell cytoplasm part", "d": [], "t": []}], "preferred_name": "host cell cytoplasm part", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1748468", "l": "condensed chromosome, centromere", "d": [], "t": []}], "preferred_name": "condensed chromosome, centromere", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0071138", "l": "alpha5-beta5-fibronectin-SFRP2 complex", "d": ["A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2."], "t": []}], "preferred_name": "alpha5-beta5-fibronectin-SFRP2 complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "90.864147894920762", "identifiers": [{"i": "GO:0036449", "l": "microtubule minus-end", "d": ["The end of a microtubule that does not preferentially grow (polymerize)."], "t": []}], "preferred_name": "microtubule minus-end", "taxa": []} {"type": "biolink:CellularComponent", "ic": "92.760008500657477", "identifiers": [{"i": "GO:0071020", "l": "post-spliceosomal complex", "d": ["A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5."], "t": []}], "preferred_name": "post-spliceosomal complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "87.17621031280774", "identifiers": [{"i": "UMLS:C1521225", "l": "2q34", "d": [], "t": []}, {"i": "NCIT:C28568", "l": "2q34", "d": ["A chromosome band present on 2q"], "t": []}], "preferred_name": "2q34", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0097059", "l": "CNTFR-CLCF1 complex", "d": ["A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). 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"collagen type VII anchoring fibril", "d": ["An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis."], "t": []}], "preferred_name": "collagen type VII anchoring fibril", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C3821240", "l": "neuromuscular junction of skeletal muscle fiber", "d": [], "t": []}], "preferred_name": "neuromuscular junction of skeletal muscle fiber", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C4235008", "l": "CoQH2-cytochrome c reductase complex", "d": [], "t": []}], "preferred_name": "CoQH2-cytochrome c reductase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0033064", "l": "XRCC2-RAD51D complex", "d": ["A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or 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During chromosomal pairing in meiosis, recombination occurs exclusively between non-sister chromatids."], "t": []}], "preferred_name": "Sister Chromatid", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C1659767", "l": "mitochondrial envelope", "d": [], "t": []}], "preferred_name": "mitochondrial envelope", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2611175", "l": "G protein complex (GNG2, GNB2L1, RAF1)", "d": [], "t": []}], "preferred_name": "G protein complex (GNG2, GNB2L1, RAF1)", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C5137258", "l": "tryptase complex", "d": [], "t": []}], "preferred_name": "tryptase complex", "taxa": []} {"type": "biolink:CellularComponent", "ic": null, "identifiers": [{"i": "UMLS:C2754746", "l": "eukaryotic translation initiation factor 3 complex, eIF3e", "d": [], "t": []}], "preferred_name": "eukaryotic translation initiation factor 3 complex, eIF3e", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0070912", "l": "Ddb1-Ckn1 complex", "d": ["A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. 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Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function."], "t": []}], "preferred_name": "archaeal-type flagellum", "taxa": []} {"type": "biolink:CellularComponent", "ic": "100", "identifiers": [{"i": "GO:0030478", "l": "actin cap", "d": ["Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. 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