name: HTR1A binds HTR1A antagonists (Caenorhabditis elegans)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + desulfo-A47934 = A47934 + adenosine 3',5'-bisphosphate + H(+)


name: 1-hexadecanoyl-sn-glycerol + ATP = 1-hexadecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: streptothricin F acid => H2O + streptothricin F


name: p-Y-YAP1 translocates to the nucleus (Homo sapiens)


name: (S)-nicotine + A + H2O = (S)-6-hydroxynicotine + AH2


name: (R)-mandelonitrile + O2 = benzoyl cyanide + H2O2


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + a fatty acid + H(+) => a 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O


name: WNTs are secreted in exosomes (Sus scrofa)


name: (3R,5S)-2,3,5,6,7-pentahydro-1,4-thiazepine-3,5-dicarboxylate + NAD(+) => (S)-cystathionine ketimine + 2 H(+) + NADH


name: DHFR2 reduces FOLA to DHF (Mus musculus)


name: Bitter compound binds bitter taste receptor (TAS2R) (Gallus gallus)


name: RIPK1 is cleaved by CASP8 (Gallus gallus)


name: [(1->2)-beta-D-mannosyl](n) + phosphate = [(1->2)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate


name: 3 CO2 + 4 CoA + orsellinate => acetyl-CoA + 2 H(+) + 3 malonyl-CoA


name: (+)-6-hydroxypinoresinol + 2 H(+) + 2 reduced [azurin] => (+)-pinoresinol + H2O + 2 oxidized [azurin]


name: Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Bos taurus)


name: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose => an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA <=> an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA + holo-[ACP]


name: Collagen XI cross-links with collagen II (Canis familiaris)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Danio rerio)


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Plasmodium falciparum)


name: EBP isomerizes ZYMSTNL to LTHSOL (Homo sapiens)


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Sus scrofa)


name: TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Rattus norvegicus)


name: Dissociation of L13a from the 60s ribosomal subunit (Canis familiaris)


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O = [DsrC protein]-S-sulfo-L-cysteine/L-cysteine + 3 AH2 + H(+)


name: PDPK1 binds PIP3 (Schizosaccharomyces pombe)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Mus musculus)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Sus scrofa)


name: H(+)(in) + L-mannopyranose(in) = H(+)(out) + L-mannopyranose(out)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Saccharomyces cerevisiae)


name: D-xylobiono-1,5-lactone + H2O2 => D-xylobiose + O2


name: Superoxide reduces cytochrome c (Caenorhabditis elegans)


name: (R)-2-methyl-3-oxopropanoate + CoA + H2O + NAD(+) <=> H(+) + hydrogencarbonate + NADH + propanoyl-CoA


name: Dimerization of PERK (Xenopus tropicalis)


name: a ubiquinol => a ubiquinone + 2 e(-) + 2 H(+)


name: D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH


name: Receptor-mediated uptake of HA (Homo sapiens)


name: 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH => 2-C-methyl-D-erythritol 4-phosphate + NADP(+)


name: 2 H(+)(out) + serotonin(in) = 2 H(+)(in) + serotonin(out)


name: 2-oxoglutarate(out) + H(+)(out) => 2-oxoglutarate(in) + H(+)(in)


name: p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Sus scrofa)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-4-phosphate) + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: L-lysyl-[protein] + NAD(+) => H(+) + N(6)-(ADP-D-ribosyl)-L-lysyl-[protein] + nicotinamide


name: Reduction of desmosterol to cholesterol (Rattus norvegicus)


name: S-adenosyl-L-methionine + scutellarein = H(+) + S-adenosyl-L-homocysteine + scutellarein 4'-methyl ether


name: IL3 stimulation induces Vav binding to Tec kinase (Homo sapiens)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Mus musculus)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: Release of SMAC (DIABLO) from mitochondria (Mus musculus)


name: ATP + H2O + methotrexate(in) = ADP + H(+) + methotrexate(out) + phosphate


name: NADP(+) + scytalone => H(+) + NADPH + naphthalene-1,3,6,8-tetrol


name: 2-acyl LPE is acylated to PE by LPEAT (Homo sapiens)


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) => 3-(3,4-dihydroxyphenyl)pyruvate + H(+) + NADH


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Dictyostelium discoideum)


name: TRPV1 binds TRPV1 blockers (Saccharomyces cerevisiae)


name: midostaurin-resistant FLT3 mutants don't bind midostaurin (Homo sapiens)


name: SLC17A3-2 transports cytosolic urate to extracellular region (Mus musculus)


name: Interaction of Tie2 and Grb2 (Homo sapiens)


name: RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Bos taurus)


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Rattus norvegicus)


name: BAP1 binds Ub-HCFC1 (Drosophila melanogaster)


name: campesteryl 3-beta-D-glucoside + H2O = campesterol + D-glucose


name: 5,10-methylenetetrahydromethanopterin + glycine + H2O = 5,6,7,8-tetrahydromethanopterin + L-serine


name: dimethylallyl diphosphate + verruculogen => diphosphate + fumitremorgin A


name: (2R,3E)-phycocyanobilin + apo-L-cysteinyl(155)-[C-phycocyanin beta-subunit] => phycocyanobilin-L-cysteinyl(155)-[C-phycocyanin beta-subunit]


name: a ganglioside GM2 (d18:1(4E)) + H2O = a ganglioside GA2 (d18:1(4E)) + N-acetylneuraminate


name: H2O + L-lysine + NADP(+) <=> (S)-2-amino-6-oxohexanoate + H(+) + NADPH + NH4(+)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Schizosaccharomyces pombe)


name: FPGS-2 transforms THF to THFPG (Rattus norvegicus)


name: 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + ATP + CoA <=> 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> mannose (a1) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Bos taurus)


name: Unwinding DNA for the nascent transcript (Rattus norvegicus)


name: SLC25A18,22 import L-Glu, H+ (Sus scrofa)


name: GGPS1 hexamer transfers IPPP to DMAPP (Sus scrofa)


name: galactitol 1-phosphate(in) + L-histidyl-[protein] => galactitol(out) + N(pros)-phospho-L-histidyl-[protein]


name: [eIF5A protein]-deoxyhypusine + AH2 + O2 <=> [eIF5A protein]-hypusine + A + H2O


name: STAMBPL1 is a deubiquitinase (Drosophila melanogaster)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Dictyostelium discoideum)


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine <=> 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: NADP(+) + UDP-2-acetamido-2,6-dideoxy-beta-L-talose => H(+) + NADPH + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose


name: (E)-4-coumaroyl-CoA + AMP + diphosphate => (E)-4-coumarate + ATP + CoA


name: TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 (Bos taurus)


name: Transport of MHC II:Ii complex along Golgi to TGN (Danio rerio)


name: Mcm4,6,7 trimer forms and associates with the replication fork (Drosophila melanogaster)


name: Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region (Homo sapiens)


name: AP-1 transcription factor, JRA:KAY, is phosphorylated by phosphorylated BSK kinase (Drosophila melanogaster)


name: MERTK receptor binds ligands (Gas6 or Protein S) (Gallus gallus)


name: (+)-pinoresinol + H2O + 2 oxidized [azurin] => (+)-6-hydroxypinoresinol + 2 H(+) + 2 reduced [azurin]


name: 2,2-dimethylsuccinate(out) + 3 Na(+)(out) = 2,2-dimethylsuccinate(in) + 3 Na(+)(in)


name: LCAT + spherical HDL <=> LCAT:spherical HDL complex (Bos taurus)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)


name: butanoate + CoA + H(+) => butanoyl-CoA + H2O


name: COPI vesicle uncoating at the ER (Homo sapiens)


name: 2-glyceryl-prostaglandin D2 => 2-glyceryl-prostaglandin H2


name: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + H2O + NAD(+) => 3,7-dideoxy-D-threo-hepto-2,6-diuolosonate + H(+) + NADH + NH4(+)


name: a dipeptide(out) + H(+)(out) => a dipeptide(in) + H(+)(in)


name: 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+) => L-tyrosine + NADPH + S-adenosyl-L-methionine


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Bos taurus)


name: 11alpha-30-dihydroxy beta-amyrin dehydrogenase activity


name: CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine (Dictyostelium discoideum)


name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Bos taurus)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Schizosaccharomyces pombe)


name: a long-chain fatty acyl-CoA(out) => a long-chain fatty acyl-CoA(in)


name: 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Bos taurus)


name: IKKbeta is activated (Rattus norvegicus)


name: ApoB-48 + 40 triacylglycerol + 60 phospholipid => ApoB-48:TG:PL complex (Bos taurus)


name: a 1,3-diacyl-sn-glycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)


name: Alpha-defensin dimers multimerize to form a pore complex (Mus musculus)


name: LTD4 is converted to LTE4 by DPEP1/2 (Mus musculus)


name: ENPP7 hydrolyzes sphingomyelin (Dictyostelium discoideum)


name: 3 H(+) + 3 malonyl-CoA + octadecanoyl-CoA <=> 4-hydroxy-6-(2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)


name: ATP + L-glutamate + L-glutamyl-[tubulin] => ADP + gamma-L-glutamyl-L-glutamyl-[tubulin] + H(+) + phosphate


name: USP47 deubiquitinates POLB (Canis familiaris)


name: TMEM55B translocates to the nucleus (Canis familiaris)


name: LONP1 degrades mitochondrial matrix proteins (Sus scrofa)


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Canis familiaris)


name: ATP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] <=> ADP + C-terminal S-cyanate-L-cysteinyl-[HypE protein] + H(+) + phosphate


name: METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Danio rerio)


name: glyoxylate + L-tryptophan <=> glycine + indole-3-pyruvate


name: PIP3 binds to RhoA and activates it (Mus musculus)


name: a 1-acyl-sn-glycerol + a fatty acid + H(+) => a 1,3-diacyl-sn-glycerol + H2O


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+) + hexadecanoate


name: UBF-1 Binds rDNA Promoter (Homo sapiens)


name: cis-4-coumarate + UDP-alpha-D-glucose <=> 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP


name: (9Z,12Z)-octadecadienoate + 1-hexadecanoylglycerone 3-phosphate => 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate


name: LRP1:Hemopexin:heme is endocytosed (Bos taurus)


name: SEC4C,D bind GOSR2 and STX5 (Schizosaccharomyces pombe)


name: A + L-sorbopyranose = 1-dehydro-L-sorbose + AH2


name: H2O + octanoyl-[ACP] => H(+) + holo-[ACP] + octanoate


name: [protein]-dithiol + [thioredoxin]-disulfide => [protein]-disulfide + [thioredoxin]-dithiol


name: 1,2-diacyl-sn-glycero-3-phospho-N-acyl-L-serine + H2O <=> 1-acyl-sn-glycero-3-phospho-N-acyl-L-serine + a fatty acid + H(+)


name: monosaccharide transmembrane transporter activity


name: precorrin-2 + S-adenosyl-L-methionine => H(+) + precorrin-3A + S-adenosyl-L-homocysteine


name: PP2A methylation by LCMT1 (Homo sapiens)


name: The 60S subunit joins the translation initiation complex  (Homo sapiens)


name: a neolactoside IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer(d18:1(4E)) + H(+) + UDP


name: an N-acylsphing-4-enine + UDP-alpha-D-galactose <=> H(+) + N-acyl-D-galactosylsphing-4-enine + UDP


name: adenosine 5'-phosphoramidate + 2 H(+) + sulfate => adenosine 5'-phosphosulfate + NH4(+)


name: Binding of PLCG1 to active TrkA receptor (Homo sapiens)


name: Anti-MET small tyrosine kinase inhibitors bind MET (Bos taurus)


name: EGF-TM7 receptors bind chondroitin sulphate (Drosophila melanogaster)


name: ERK1/2/5 activate RSK1/2/3 (Dictyostelium discoideum)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA = [N,O(9)-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: benzene-1,2,4-triol + CO2 + H2O + NAD(+) => 3,4-dihydroxybenzoate + 2 H(+) + NADH + O2


name: Na+/H+ exchanger transport (at cell membrane) (Danio rerio)


name: (S)-2-hydroxyglutarate + A = 2-oxoglutarate + AH2


name: Interleukin-1 family are secreted (Xenopus tropicalis)


name: TAK1 phosphorylates MKK6 (Rattus norvegicus)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Gallus gallus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Sus scrofa)


name: 4-hydroxyestrone + NH4(+) + O2 <=> 2 H(+) + 2 H2O + pyridinestrone carboxylate


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Sus scrofa)


name: 1-hexadecanoylglycerone 3-phosphate + tetradecan-1-ol => 1-O-tetradecylglycerone 3-phosphate + H(+) + hexadecanoate


name: L-arginyl-L-alpha-amino acid(in) => L-arginyl-L-alpha-amino acid(out)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Danio rerio)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Saccharomyces cerevisiae)


name: IDO2 dioxygenates L-Trp to NFK (Bos taurus)


name: PM20D1 hydrolyzes oleoyl-phe (Mus musculus)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O <=> [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phospho-L-serine


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Mus musculus)


name: H(+) + O-phospho-L-threonine => (R)-1-aminopropan-2-yl phosphate + CO2


name: 4 hydroquinone + O2 => 4 benzosemiquinone + 2 H2O


name: MeSeO2H is reduced to MeSeOH by TXNRD1 (Caenorhabditis elegans)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Homo sapiens)


name: LIG1 bound to APEX1 and PCNA ligates SSB (Sus scrofa)


name: Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Rattus norvegicus)


name: an N-(1,2-saturated acyl)sphinganine + H(+) + NADPH + O2 => an N-(2-hydroxyacyl)-sphinganine + H2O + NADP(+)


name: Interaction of integrin alphaIIbbeta3 with von Willebrand factor (Homo sapiens)


name: USP1:WDR48 binds monoUb:K164-PCNA (Bos taurus)


name: 2-oxoadipate + O2 => (R)-2-hydroxyglutarate + CO2


name: 1-O-alkylglycerone 3-phosphate + H(+) + NADPH = 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)


name: ATP + ethylamine + L-glutamate => ADP + H(+) + N(5)-ethyl-L-glutamine + phosphate


name: dodecapentaneoyl-[polyketide synthase] + fumagillol = holo-[polyketide synthase] + prefumagillin


name: WG, FZ and ARR bind to each other (Drosophila melanogaster)


name: 2-methylpropanenitrile + H2O => (Z)-2-methylpropanal oxime


name: Formation of the Spliceosomal Bact complex (Sus scrofa)


name: GTP + S-adenosyl-L-methionine <=> N(7)-methyl-GTP + S-adenosyl-L-homocysteine


name: IMPDH tetramers binds IMPDH inhibitors (Drosophila melanogaster)


name: ATP + fluconazole(in) + H2O = ADP + fluconazole(out) + H(+) + phosphate


name: RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)


name: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH


name: L-methionine(in) + Na(+)(in) = L-methionine(out) + Na(+)(out)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Homo sapiens)


name: Glucagon:GCGR mediates GTP-GDP exchange (Homo sapiens)


name: LRP2-mediated TCN2:RCbl uptake and delivery to lysosome (Bos taurus)


name: 24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Dictyostelium discoideum)


name: ASPA deacetylates NAA to acetate and L-aspartate (Danio rerio)


name: 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + O2 = CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate


name: TCR complex interacts with peptide antigen-presenting MHC Class I (Sus scrofa)


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Danio rerio)


name: DNA-binding transcription activator activity


name: NFE2L2 dependent AREG expression (Homo sapiens)


name: RFC dissociates after sliding clamp formation on the C-strand of the telomere (Sus scrofa)


name: (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2


name: a 5'-end 5'-phospho-ribonucleoside-2'-deoxyribonucleotide-DNA + AMP + 2 H(+) => a 5'-end adenosine-5'-diphospho-5'-ribonucleoside-2'-deoxyribonucleotide-DNA + H2O


name: H2O + L-glutamate 5-semialdehyde + NAD(+) => 2 H(+) + L-glutamate + NADH


name: (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 <=> (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate


name: SUMOylation of Histone H4 with SUMO1 (Saccharomyces cerevisiae)


name: (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA <=> (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA + H2O


name: RHOC binds effectors at the plasma membrane (Canis familiaris)


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Canis familiaris)


name: CDP-choline + sphing-4-enine = CMP + H(+) + sphing-4-enine-phosphocholine


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Bos taurus)


name: N-ethylsuccinimide + NAD(+) => H(+) + N-ethylmaleimide + NADH


name: (2R,3S)-3-isopropylmalate <=> 2-isopropylmaleate + H2O


name: H2O + N-benzylformamide <=> benzylamine + formate


name: Ca permeable AMPA receptor ligand binding (Mus musculus)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Homo sapiens)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Bos taurus)


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Mus musculus)


name: 5-(3-methylguanidino)-2-oxopentanoate + L-alanine => N(omega)-methyl-L-arginine + pyruvate


name: TRAF1 is cleaved by caspases (Homo sapiens)


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Mus musculus)


name: Association of DFF40 with DFF45 (Mus musculus)


name: 5beta-dihydrotestosterone + NADP(+) <=> H(+) + NADPH + testosterone


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Caenorhabditis elegans)


name: PKA phosphorylates GLI3 (Canis familiaris)


name: SIRPA binds SFTPA oligomer, SFTPD oligomer (Homo sapiens)


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP => an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Sus scrofa)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Dictyostelium discoideum)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate <=> 5-oxo-(6E,8Z,11Z,14Z)-eicosatetraenoate + H2O


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Plasmodium falciparum)


name: Dissociation of Cdc20 from APC/C complex (Sus scrofa)


name: ST6GALNAC5,6 transfer Neu5Ac to GM1b (Sus scrofa)


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Homo sapiens)


name: all-trans-antheraxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => all-trans-zeaxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Caenorhabditis elegans)


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)


name: (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + 2-oxoglutarate + AH2 + H(+) + O2 <=> (2S)-5,5-dimethylpiperidine-2-carboxylate + A + 2 CO2 + H2O + succinate


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Homo sapiens)


name: H2O + mevastatin = (S)-2-methylbutanoate + compactin diol lactone + H(+)


name: Brevican degradation by ADAMTS4, ADAMTS5 (Mus musculus)


name: [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose <=> [(1->4)-alpha-D-glucosyl](n+1) + H(+) + UDP


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Gallus gallus)


name: aluminum ion transmembrane transporter activity


name: Full activation of MMP1 (Caenorhabditis elegans)


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Mus musculus)


name: LINC01139 promotes phosphorylation of HIF1A by PTK6 (Sus scrofa)


name: Follicle-stimulating hormone receptor can bind FSH (Mus musculus)


name: a 5'-end ribonucleotide-tRNA(His) + ATP + H(+) <=> a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate


name: SRD5A3 dehydrogenates TEST to DHTEST (Bos taurus)


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Xenopus tropicalis)


name: a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine


name: IGFBP3 binds TMEM219 (Rattus norvegicus)


name: CYP4F12 18-hydroxylates ARA (Homo sapiens)


name: quercetin + S-adenosyl-L-methionine = H(+) + isorhamnetin + S-adenosyl-L-homocysteine


name: acetoin + H(+) + NADPH + NH4(+) => 3-aminobutan-2-ol + H2O + NADP(+)


name: cholest-4-en-3-one + H(+) + NADPH => 5beta-cholestan-3-one + NADP(+)


name: Exocytosis of platelet alpha granule contents (Rattus norvegicus)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) => beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B1)


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Caenorhabditis elegans)


name: Rnd1 interacts with Plexin-B1:Sema4D (Xenopus tropicalis)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2 <=> (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O


name: GDP-beta-L-fucose(in) + GMP(out) => GDP-beta-L-fucose(out) + GMP(in)


name: eicosanoyl-CoA + glycine => CoA + H(+) + N-eicosanoylglycinate


name: (2R,4S)-ketoconazole(in) + ATP + H2O <=> (2R,4S)-ketoconazole(out) + ADP + H(+) + phosphate


name: (9Z)-octadecenoyl-CoA + 1-octanoylglycerol <=> 1-octanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: PDPK1 (PDK1) phosphorylates PKN2 on threonine-816 (Homo sapiens)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Schizosaccharomyces pombe)


name: 2-acyl LPC is acylated to PC by LPCAT (Xenopus tropicalis)


name: SCD5 desaturates ST-CoA to OLE-CoA (Homo sapiens)


name: AMP + an aldehyde + diphosphate + NADP(+) => a carboxylate + ATP + H(+) + NADPH


name: (E)-4-hydroxynon-2-en-1-ol + NAD(+) <=> (E)-4-hydroxynon-2-enal + H(+) + NADH


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Caenorhabditis elegans)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Dictyostelium discoideum)


name: 4-hydroxyeicosasphinganine 1-phosphate + H2O = (4R)-hydroxyeicosasphinganine + phosphate


name: RAF1 binds p21 RAS:GTP (Rattus norvegicus)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: (2E)-decenoyl-CoA + H(+) + oxaloacetate => (4-octa-1-enyl-2,5-dioxo-2,5-dihydro-3-furanyl)acetate + CoA + H2O


name: 2 Na(+)(out) + urate(out) = 2 Na(+)(in) + urate(in)


name: IL6R binds IL6R inhibitors (Danio rerio)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Sus scrofa)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Homo sapiens)


name: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Gallus gallus)


name: Coumarin is 7-hydroxylated by CYP2A6 (Caenorhabditis elegans)


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Canis familiaris)


name: Secretin receptor binds secretin (Homo sapiens)


name: CDK1:CCNB phosphorylates NEK9 (Mus musculus)


name: PTGS1 dimer binds PTGS1 Inhibitors (Canis familiaris)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Mus musculus)


name: CMBL hydrolyses OM to OLMS (Danio rerio)


name: STAT5 is recruited by JAK2 (Rattus norvegicus)


name: H2O + NADP(+) + pentylamine <=> H(+) + NADPH + NH4(+) + pentanal


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Sus scrofa)


name: The complex of RUNX1 and YAP1 binds the ITCH gene promoter (Homo sapiens)


name: STRA6 transports atROL from extracellular region to cytosol (Gallus gallus)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Mus musculus)


name: Gq activation by TP receptor (Canis familiaris)


name: NFE2L2 dependent PDGFA expression (Homo sapiens)


name: USP11 deubiquitinates NFKBIA (Sus scrofa)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Sus scrofa)


name: (R)-pantoate + ATP + beta-alanine => (R)-pantothenate + AMP + diphosphate + H(+)


name: Dynamin-mediated GTP hydrolysis promotes vesicle scission (Rattus norvegicus)


name: p-AMPK:AMP binds the ULK complex (Mus musculus)


name: IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)


name: nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Sus scrofa)


name: p62 links damaged mitochondria to LC3 (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + hexadecanoyl-CoA


name: ABCB4 transports PC from plasma membrane to extracellular region (Gallus gallus)


name: WLS is endocytosed to the early endosome (Bos taurus)


name: GTSE1 promotes translocation of TP53 to the cytosol (Sus scrofa)


name: 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA (Sus scrofa)


name: 10-deacetyltaxuyunnanin C + acetyl-CoA <=> CoA + taxuyunnanin C


name: (5S)-hydroperoxy-(6E,8Z)-octadecadienoate + 2 glutathione => (5S)-hydroxy-(6E,8Z)-octadecadienoate + glutathione disulfide + H2O


name: 7-deoxyloganin + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + loganin + oxidized [NADPH--hemoprotein reductase]


name: KLK5 cleaves and activates KLK8 (Rattus norvegicus)


name: AKR1C3 reduces atRAL to atROL (Dictyostelium discoideum)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Danio rerio)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (-)-alpha-acorenol + diphosphate


name: dodecanoyl-CoA + H(+) + L-serine = 3-oxotetradecasphinganine + CO2 + CoA


name: Recruitment of  RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Drosophila melanogaster)


name: SUMOylation of MDC1 with SUMO2,3 (Mus musculus)


name: a dipeptide(in) + H(+)(in) => a dipeptide(out) + H(+)(out)


name: demethylphylloquinol + NADP(+) => demethylphylloquinone + H(+) + NADPH


name: 6-hydroxyphenazine-1-carboxylate + 2 H(+) + NADH + O2 => 1,6-dihydroxyphenazine + CO2 + H2O + NAD(+)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Rattus norvegicus)


name: Growth hormone forms dimers and oligomers (Mus musculus)


name: 2,2-dihydroxyspheroidene = H2O + spheroiden-2-one


name: ANKH transports PPi from cytosol to extracellular region (Bos taurus)


name: STAT1 and STAT3 dimers translocate to the nucleus (Xenopus tropicalis)


name: L-histidine(out) + L-tryptophan(in) => L-histidine(in) + L-tryptophan(out)


name: L-asparagine(in) + L-glutamine(out) + Na(+)(out) => L-asparagine(out) + L-glutamine(in) + Na(+)(in)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Rattus norvegicus)


name: Resolution of sister chromatids (Mus musculus)


name: diphosphate + geranylgeranyl-bacteriochlorophyllide a => (2E,6E,10E)-geranylgeranyl diphosphate + bacteriochlorophyllide a + H(+)


name: L-histidinol + phosphate => H2O + L-histidinol phosphate


name: NCOA1 recruits EP300 to TGFA promoter (Homo sapiens)


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Bos taurus)


name: Cleavage of uracil by SMUG1 glycosylase (Canis familiaris)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Canis familiaris)


name: a carotenoid chi-end derivative + 2 AH2 => 2 A + a carotenoid beta-end derivative


name: Association of procollagen type XXVI (Canis familiaris)


name: TP53 forms homotetramers (Drosophila melanogaster)


name: MRN bound to shortened telomeres activates ATM (Drosophila melanogaster)


name: (5Z)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: high mobility group box 1 receptor activity


name: Activation of CHEK1 at resected DNA DSBs (Homo sapiens)


name: ALDH7A1 oxidises BETALD to BET (Homo sapiens)


name: voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Bos taurus)


name: butanoyl-CoA + tyramine = CoA + H(+) + N-butanoyltyramine


name: PTGS2 dimer oxidises DHA to 13-HDHA (Sus scrofa)


name: AURKA phosphorylates PLK1 (Gallus gallus)


name: ATP + hygromycin B => 4-O-phosphohygromycin B + ADP + H(+)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Dictyostelium discoideum)


name: H2O + L-tryptophan + O2 = H2O2 + indole-3-pyruvate + NH4(+)


name: 6-tuliposide B => D-glucose + tulipalin B


name: TP53 binds the ARID3A gene (Homo sapiens)


name: cinerin II + CoA => (1R,3R)-pyrethroyl-CoA + (Z,S)-cinerolone


name: Activated protein C cleaves factor VIIIa (Gallus gallus)


name: 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxoglutarate + L-proline + O2 => CO2 + succinate + trans-4-hydroxy-L-proline


name: 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out) => 3,3',5-triiodo-L-thyronine(out) + L-glutamate(in)


name: hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Drosophila melanogaster)


name: a hydroperoxyeicosatetraenoate => a hydroxy-epoxy-eicosatetraenoate


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) <=> 5,7-dihydroxy-4-methylphthalide + H2O


name: abacavir [extracellular] => abacavir [cytosol] (Gallus gallus)


name: chlorogenate + H2O = (E)-caffeate + H(+) + L-quinate


name: 2 5,6-dihydroxyindole-2-carboxylate + O2 <=> 2 H2O + 2 indole-5,6-quinone-2-carboxylate


name: AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Rattus norvegicus)


name: 2-oxoglutarate + methylphosphonate + O2 => CO2 + hydroxymethylphosphonate + succinate


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Drosophila melanogaster)


name: TBC1D7 binds the TSC1-TSC2 complex (Mus musculus)


name: hexadecanoyl-CoA + sphinga-(4E,8Z)-dienine => CoA + H(+) + N-hexadecanoylsphinga-(4E,8Z)-dienine


name: ABCC4 accumulation of dense granule contents (Bos taurus)


name: demethylphylloquinol + S-adenosyl-L-methionine = H(+) + phylloquinol + S-adenosyl-L-homocysteine


name: 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] <=> 17beta,18-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Salvage - Sepiapterin is reduced to q-BH2 (Canis familiaris)


name: IFN alpha/beta binds to IFNAR2 (Gallus gallus)


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA => (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: a 2-demethylmenaquinone + S-adenosyl-L-methionine => a menaquinone + H(+) + S-adenosyl-L-homocysteine


name: CDC42:GTP binds CBL:Beta-Pix (Caenorhabditis elegans)


name: AMP + diphosphate + dodecanoyl-[ACP] => ATP + dodecanoate + holo-[ACP]


name: 10R-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate => (6Z,9Z,12Z)-octadecatrienoate + O2


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Sus scrofa)


name: Kinesins bind microtubules (Mus musculus)


name: (3R)-3-hydroxy-L-arginyl-[protein] + CO2 + succinate => 2-oxoglutarate + L-arginyl-[protein] + O2


name: atromentin + 2 H2O => 2 3-(4-hydroxyphenyl)pyruvate + H(+)


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Mus musculus)


name: 2,4,6-trinitrotoluene + 2 H(+) + 2 NADH = 4-hydroxylamino-2,6-dinitrotoluene + H2O + 2 NAD(+)


name: an aldehyde + H2O + O2 = a carboxylate + H(+) + H2O2


name: (2R,4S)-bornyl diphosphate => (2E)-geranyl diphosphate


name: (3S)-hydroxyoctanedioyl-CoA + NAD(+) <=> 3-oxooctanedioyl-CoA + H(+) + NADH


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Schizosaccharomyces pombe)


name: TRPV4 tetramer:CALM1:Ca2+ transports calcium ions (Ca2+) from the extracellular region to the cytosol (Homo sapiens)


name: CBX3 and PRC1.6 associate with E2F6.com-1 (Rattus norvegicus)


name: CBL ubiquitinates PI3K (Canis familiaris)


name: H(+) + O-(N-acetyl-alpha-D-glucosaminyl)-L-tyrosyl-[protein] + UDP => L-tyrosyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: KCNK dimers transport K+ from cytosol to extracellular region (Mus musculus)


name: BTG2 binds CCR4-NOT complex (Bos taurus)


name: a 3beta-hydroxysteroid + a triacylglycerol => a 3beta-hydroxysteroid ester + a diacylglycerol


name: (1S,2R)-ephedrine + NAD(+) = (R)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: (4,5-dihydro-5-oxofuran-2-yl)-acetate + H2O = 3-oxoadipate + H(+)


name: amicoumacin A + ATP = ADP + amicoumacin A 2-phosphate + H(+)


name: cholesterol + UDP-alpha-D-galactose <=> cholesteryl 3-beta-D-galactoside + H(+) + UDP


name: Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP (Homo sapiens)


name: UROS transforms HMB to URO3 (Xenopus tropicalis)


name: H2O + N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine <=> a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H(+) + sulfate


name: (2E,6E)-farnesyl diphosphate + H2O = diphosphate + koraiol


name: PSMG1:PSMG2 dimer binds the 20S core particle outer ring (Drosophila melanogaster)


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Drosophila melanogaster)


name: Exocytosis of specific granule membrane proteins (Canis familiaris)


name: H2O + N-(9Z-octadecenoyl)-L-glutamate <=> (9Z)-octadecenoate + L-glutamate


name: H2O2 + NH4(+) + pyridoxal => H2O + O2 + pyridoxamine


name: Fe3+ dissociates from holoTF:TFRC dimer (Mus musculus)


name: a 2-acyl-sn-glycero-3-phosphocholine + H2O => a fatty acid + H(+) + sn-glycerol 3-phosphocholine


name: CDK2 phosphorylates RBBP8 (Mus musculus)


name: Exogenous soluble antigen targeted to more stable early endosome (Homo sapiens)


name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 (Sus scrofa)


name: 12-hydroxydodecanoate + NAD(+) = 12-oxododecanoate + H(+) + NADH


name: glyceraldehyde dehydrogenase (NADP+) activity


name: dopamine + L-glutaminyl-[protein] => 5-dopaminyl-L-glutamyl-[protein] + NH4(+)


name: a hydroperoxide + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] => an alcohol + H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: 5alpha-androstan-3,17-dione + H(+) + NADPH => 3beta-hydroxy-5alpha-androstan-17-one + NADP(+)


name: adenine + alpha-D-ribose 1-methylphosphonate 5-triphosphate => ATP + methylphosphonate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Sus scrofa)


name: (2Z,6Z)-farnesyl diphosphate = (+)-endo-beta-bergamotene + diphosphate


name: "(+)-endo-beta-bergamotene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing]"


name: D-tryptophanyl-tRNA(Trp) + H2O = D-tryptophan + tRNA(Trp)


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Drosophila melanogaster)


name: 2 3-(4-hydroxyphenyl)pyruvate + O2 = 2 4-hydroxyphenylacetate + 2 CO2


name: H2O + indole-3-acetamide <=> (indol-3-yl)acetate + NH4(+)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: myricetin + UDP-alpha-D-glucose = H(+) + myricetin 3-O-beta-D-glucoside + UDP


name: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Xenopus tropicalis)


name: ADP + D-sedoheptulose 7-phosphate + H(+) => ATP + sedoheptulose


name: Interaction of Tie2 and Grb7 (Xenopus tropicalis)


name: SUCLG1/A2 cleaves succinyl-CoA (Dictyostelium discoideum)


name: PIAS2-2 SUMOylates SUZ12 with SUMO1 (Saccharomyces cerevisiae)


name: D-cycloserine(in) + H(+)(in) = D-cycloserine(out) + H(+)(out)


name: Protease binds protease inhibitors (Homo sapiens)


name: an N-methyl-L-amino acid + H2O + O2 = an L-alpha-amino acid + formaldehyde + H2O2


name: Activated FGFR4:p-FRS binds GRB2:SOS1 (Mus musculus)


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Rattus norvegicus)


name: Beta-catenin migrates to the nucleus (Caenorhabditis elegans)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(in) + ATP + H2O => ADP + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(out) + H(+) + phosphate


name: NEIL1 cleaves DHU from damaged DNA (Homo sapiens)


name: 2 Na(+)(in) + taurochenodeoxycholate(in) => 2 Na(+)(out) + taurochenodeoxycholate(out)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine => a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + H(+) + S-adenosyl-L-homocysteine


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Rattus norvegicus)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Sus scrofa)


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Mus musculus)


name: GSDME (1-270) binds cardiolipin (Xenopus tropicalis)


name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Mus musculus)


name: anthocyanidin 3-O-glucoside 6''-O-acyltransferase activity


name: Phosphorylation of SHC1 by ERBB4 homodimers (Canis familiaris)


name: 3-hydroxy-3-methylglutarate + succinyl-CoA => (3S)-hydroxy-3-methylglutaryl-CoA + succinate


name: guanosine(2535) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylguanosine(2535) in 23S rRNA + S-adenosyl-L-homocysteine


name: Ubiquitination of stimulated EGFR (CBL) (Sus scrofa)


name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + variediene


name: (1E,2S)-2-methylbutanal oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-isoleucine


name: POM121 and NDC1 bind the Nup93 complex (Rattus norvegicus)


name: ITP + N-acetyl-D-glucosamine = H(+) + IDP + N-acetyl-D-glucosamine 6-phosphate


name: Phosphorylation of PKC theta (Canis familiaris)


name: USP20, USP33 deubiquitinate ADRB2 (Rattus norvegicus)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Mus musculus)


name: 3-phenylpropanal + AMP + diphosphate + NADP(+) => 3-phenylpropanoate + ATP + H(+) + NADPH


name: H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphate = N-acyl-15-methylhexadecasphing-4-enine + phosphate


name: D-xylotetraose + O2 => D-xylotetraono-1,5-lactone + H2O2


name: CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) (Rattus norvegicus)


name: H2O + NAD(+) + xanthine => H(+) + NADH + urate


name: a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)


name: P2X1-mediated entry of Ca++ from plasma (Sus scrofa)


name: 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = 25-hydroxy-24-oxocalciol + 2 H2O + 2 oxidized [adrenodoxin]


name: GTP + L-histidyl-[RNA ligase] => diphosphate + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase]


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Schizosaccharomyces pombe)


name: all-trans-4-hydroxyretinol + NAD(+) <=> all-trans-4-hydroxyretinal + H(+) + NADH


name: (2E,6E)-farnesyl diphosphate => diphosphate + gamma-gurjunene


name: 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: HOXB1 maintains activation of HOXB1 chromatin (Homo sapiens)


name: Binding of STAT1 to p-IFNGR1 (Danio rerio)


name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (Mus musculus)


name: CDC42 translocates to the endoplasmic reticulum membrane (Sus scrofa)


name: 2-methylbenzyl alcohol + O2 = 2-methylbenzaldehyde + H2O2


name: Binding of ADAR1 homodimer to dsRNA duplex (Homo sapiens)


name: Formation of Pol zeta complex (Gallus gallus)


name: PLK1 phosphorylates FIRRM at S43 (Sus scrofa)


name: SMYD2 methylates TP53 (Canis familiaris)


name: Generation of a DNA double strand break (Gallus gallus)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphate + H(+) + NADPH => 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphate + NADP(+)


name: CoA-glutathione reductase (NADPH) activity


name: NF-kappaB translocates from the cytosol to the nucleus (Xenopus tropicalis)


name: PAK1 or PAK2 phosphorylates MYLK (Canis familiaris)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Homo sapiens)


name: Cleavage of DFF45 (224) by caspase-3 (Xenopus tropicalis)


name: 3-O-[N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + CMP + H(+) => CMP-N-acetyl-beta-neuraminate + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein]


name: H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2


name: diglucosyl diacylglycerol synthase activity


name: coclaurine + H(+) + S-adenosyl-L-homocysteine => norcoclaurine + S-adenosyl-L-methionine


name: Inner coat assembly and cargo binding (Bos taurus)


name: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate


name: (S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+) => ATP + H(+) + L-2-aminoadipate + NADPH


name: 11-hydroxysugiol + O2 + reduced [NADPH--hemoprotein reductase] => 11,20-dihydroxysugiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + sphinganine => CoA + H(+) + N-(9Z-octadecenoyl)-sphinganine


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + succinate


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA <=> (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA + H2O


name: 1-beta-D-galactosyl-2,3-didodecanoyl-sn-glycerol + H2O => 1-beta-D-galactosyl-dodecanoyl-sn-glycerol + dodecanoate + H(+)


name: HOXA3 gene is transcribed (Homo sapiens)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)


name: 7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate


name: goitrin + sulfate => (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate


name: (R)-malate(out) + 2 H(+)(out) => (R)-malate(in) + 2 H(+)(in)


name: Active G alpha (z) binds RGS proteins (Xenopus tropicalis)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Danio rerio)


name: ATP + CoA + dodecanedioate = AMP + diphosphate + dodecanedioyl-CoA


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Dictyostelium discoideum)


name: a 5,6-dihydrouridine in tRNA + NAD(+) <=> a uridine in tRNA + H(+) + NADH


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CLCN4/5/6 exchange Cl- for H+ (Caenorhabditis elegans)


name: ATP + H(+) + salicylate => 2-hydroxybenzoyl-5'-AMP + diphosphate


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 <=> (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate


name: an N(2)-(1-hydroxy-2-oxoethyl)-guanosine in RNA + H2O => a guanosine in RNA + glycolate + H(+)


name: FUT3 transfers Fuc to Type 1 DSGG to form dsLeA (Bos taurus)


name: H2O + quercetin 4'-O-beta-D-glucoside <=> beta-D-glucose + quercetin


name: N-(8'-hydroxygeranyl)-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + N-(8'-oxogeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase]


name: ABL1 phosphorylates RAD52 (Mus musculus)


name: 3'-N-debenzoyl-2'-deoxytaxol + AH2 + O2 <=> 3'-N-debenzoyltaxol + A + H2O


name: ATP + daunorubicin(in) + H2O => ADP + daunorubicin(out) + H(+) + phosphate


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Homo sapiens)


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + H(+) + H2O = Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + N-(2,3-dihydroxybenzoyl)-L-serine


name: RhCG mediates ammonium influx into kidney collecting duct cells (Dictyostelium discoideum)


name: N-demethylindolmycin + S-adenosyl-L-methionine <=> H(+) + indolmycin + S-adenosyl-L-homocysteine


name: soyasapogenol A + UDP-alpha-D-glucuronate <=> H(+) + soyasapogenol A 3-O-beta-D-glucuronate + UDP


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Gallus gallus)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Drosophila melanogaster)


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Bos taurus)


name: NTPDase8 hydrolyzes nucleoside triphosphates (Canis familiaris)


name: H(+)(in) + L-serine(out) + Na(+)(out) => H(+)(out) + L-serine(in) + Na(+)(in)


name: glycolate + H(+) + L-arginyl-[protein] => H2O + N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein]


name: Dephosphorylation of STAT1 by SHP2 (Bos taurus)


name: 2-demethylmenaquinone-8 + H(+) + NADPH => 2-demethylmenaquinol-8 + NADP(+)


name: (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] => 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Saccharomyces cerevisiae)


name: [Wnt protein]-O-(9Z)-hexadecenoyl-L-serine + H2O = (9Z)-hexadecenoate + [Wnt protein]-L-serine + H(+)


name: "[Wnt protein] O-palmitoleoyl-L-serine hydrolase"


name: Formation of the preholoproteasome (Schizosaccharomyces pombe)


name: (2E,6E)-farnesyl diphosphate = diphosphate + trichodiene


name: H2O + S-ethyl-L-cysteine <=> ethanethiol + NH4(+) + pyruvate


name: a jasmonate + an L-alpha-amino acid + ATP => a jasmonyl-L-amino acid + AMP + diphosphate + H(+)


name: Ubiquitinated geminin is degraded by the proteasome (Gallus gallus)


name: 27-hydroxysterol binds ESR1, ESR2 (Sus scrofa)


name: luteolin + S-adenosyl-L-methionine = chrysoeriol + H(+) + S-adenosyl-L-homocysteine


name: TDG excises 5-carboxylcytosine (Schizosaccharomyces pombe)


name: a quinone + H2O + sulfite <=> a quinol + sulfate


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Rattus norvegicus)


name: Exocytosis of Proactivator polypeptide (Gallus gallus)


name: Association of Acrosin Heavy and Light Chain (Sus scrofa)


name: Phosphorylation of LAT by p-SYK (Bos taurus)


name: MRN complex binds shortened telomeres (Rattus norvegicus)


name: H2O + sucrose 6(F)-phosphate => beta-D-fructose + beta-D-glucose 6-phosphate


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Canis familiaris)


name: DCA binds PDK2 (Drosophila melanogaster)


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Rattus norvegicus)


name: 2 5'-deoxyadenosine + a bacteriochlorophyllide f + 2 H(+) + 2 L-methionine => a bacteriochlorophyllide d + H2O + 2 S-adenosyl-L-methionine


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Xenopus tropicalis)


name: Association of  PARVA with TESK1 (Homo sapiens)


name: 6-hydroxyhexanoate + NADP(+) => 6-oxohexanoate + H(+) + NADPH


name: XYLB phosphorylates D-xylulose (Sus scrofa)


name: DRD2 antagonist drugs bind to DRD2 (Mus musculus)


name: VDR agonists bind VDR (Drosophila melanogaster)


name: EP300 acetylates RUNX3 (Rattus norvegicus)


name: PIAS1 SUMOylates THRB with SUMO3 (Mus musculus)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: a D-hexose + an acyl phosphate = a carboxylate + D-hexose phosphate + H(+)


name: Regulation of KIF20A (MKL2) by phosphorylation (Rattus norvegicus)


name: Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (Mus musculus)


name: carboxyspermidine dehydrogenase II activity


name: Formation of FACT complex (Xenopus tropicalis)


name: (3Z)-phycoerythrobilin + 2 oxidized 2[4Fe-4S]-[ferredoxin] <=> biliverdin IXalpha + 4 H(+) + 2 reduced 2[4Fe-4S]-[ferredoxin]


name: a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GD2 (d18:1(4E)) + H(+) + UDP


name: Edg-6 sphingosine 1-phosphate receptor binding


name: USP19 binds HIF1A,BIRC2,BIRC3 (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ADP + H(+) + phosphate => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ATP + H2O


name: hydroquinone + UDP-alpha-D-glucose <=> H(+) + hydroquinone O-beta-D-glucopyranoside + UDP


name: S100B gene expression is inhibited by ERBB4:TAB2:NCOR1 (Homo sapiens)


name: 3-oxochol-4-en-22-oyl-CoA + acetyl-CoA => 3,22-dioxochol-4-en-24-oyl-CoA + CoA


name: beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA (Drosophila melanogaster)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Mus musculus)


name: a (R)-2-hydroxy fatty acid + O2 => a fatty acid + CO2 + H2O


name: SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Rattus norvegicus)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Mus musculus)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Dictyostelium discoideum)


name: ATP + H2O + L-aspartate(out) => ADP + H(+) + L-aspartate(in) + phosphate


name: RBX1:CUL3 dissociates from forming autophagosome (Bos taurus)


name: SLC44A1 transports Cho from cytosol to mitochondrial matrix (Xenopus tropicalis)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Homo sapiens)


name: WNT ligands traffic to the Golgi (Mus musculus)


name: UMPS dimer decarboxylates OMP to UMP (Homo sapiens)


name: Phosphorylation of SLP-76 by p-SYK (Rattus norvegicus)


name: 4 H(+) + 6 H2O + 4 oxidized [NADPH--hemoprotein reductase] + variecolin => 4 O2 + 4 reduced [NADPH--hemoprotein reductase] + variecoladiene


name: STAT1 and STAT3 dimers translocate to the nucleus (Danio rerio)


name: Glycosylation of Pre-NOTCH by FRINGE (Homo sapiens)


name: PHLPP dephosphorylates S473 in AKT (Drosophila melanogaster)


name: CALR, TAP, TAPBP dissociate from SEC22B:STX4 (Mus musculus)


name: Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE (Xenopus tropicalis)


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Mus musculus)


name: Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Homo sapiens)


name: Cytosolic PLK1 translocates to the nucleus (Mus musculus)


name: 2 CO2 + 4 H2O + heme b => Fe-coproporphyrin III + 2 H(+) + 2 H2O2


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Rattus norvegicus)


name: Pre-pro-defensins are cleaved to remove the signal peptide (Sus scrofa)


name: Phosphorylation of CBL (EGFR:CBL) (Drosophila melanogaster)


name: CBL binds TGFBR2 (Caenorhabditis elegans)


name: FRAT proteins bind GSK3beta (Gallus gallus)


name: TP53 stimulates NDRG1 gene expression (Homo sapiens)


name: NKG2D homodimer interacting with ligands (Rattus norvegicus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine => 1,2-dihexadecanoyl-sn-glycerol + a sphingomyelin


name: Uncoupled eNOS favours the formation of superoxide (Caenorhabditis elegans)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Caenorhabditis elegans)


name: cholate + UDP-alpha-D-glucuronate <=> choloyl-24-O-(beta-D-glucuronate) + UDP


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Caenorhabditis elegans)


name: 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-4H,6H,7H,8H-pyrrolo[1,2-a]pyrazine + NADP(+) => 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + H(+) + NADPH


name: NOTCH1 t(7;9)(NOTCH1:M1580_K2555) does not bind JAG1 (Homo sapiens)


name: a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + H2O => a di-trans,poly-cis-dolichyl phosphate + D-glucose + H(+)


name: Cho is phosphorylated to PCho by CHK dimer (Canis familiaris)


name: H(+) + NADH + phylloquinone => NAD(+) + phylloquinol


name: ZnT1 mediates the efflux of zinc from the cell (Mus musculus)


name: H2O + TTP = 5-methyl-UMP + diphosphate + H(+)


name: I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol (Mus musculus)


name: USP28 deubiquitinates CLSPN and MYC (Bos taurus)


name: RNF41 binds neuregulin-activated ERBB3 (Rattus norvegicus)


name: JMJD6 demethylates Me2R3-histone H3 (Canis familiaris)


name: B4GALTs transfer Gal to a branch of keratan (Canis familiaris)


name: dodecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 4-hydroxy-6-undecylpyran-2-one + 2 CO2 + 3 CoA


name: De novo formation of eIF2:GTP (Caenorhabditis elegans)


name: GREB1 binds ESR1:ESTG and co-activators (Gallus gallus)


name: p-T,Y MAPK dimers translocate to nucleus (Caenorhabditis elegans)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Canis familiaris)


name: H(+) + mycinamicin III + S-adenosyl-L-homocysteine => mycinamicin VI + S-adenosyl-L-methionine


name: ADP + H(+) + L-tryptophan(in) + phosphate => ATP + H2O + L-tryptophan(out)


name: ALDH3B2 oxidises HXAL to PALM (Dictyostelium discoideum)


name: Receptor FFAR2 binds carboxylates (Gallus gallus)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Drosophila melanogaster)


name: diphosphate + pppA(2'-5')pG => ATP + GTP


name: O2 + octanoyl-CoA = (2E)-octenoyl-CoA + H2O2


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Homo sapiens)


name: Protein 4.1 binds CASK (Rattus norvegicus)


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Xenopus tropicalis)


name: STAT5 is recruited by JAK2 (Canis familiaris)


name: (E)-hex-2-enal + H(+) + NADPH => (E)-hex-2-en-1-ol + NADP(+)


name: Autophosphorylation of insulin receptor (Danio rerio)


name: (5'S,6'R)-C-glycyluridine + O2 <=> CO2 + H2O + uridine-5'-carboxamide


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: miR-25 microRNA binds PTEN mRNA (Homo sapiens)


name: NEIL1 cleaves FapyG from damaged DNA (Homo sapiens)


name: TFAP2C translocates to the nucleus (Danio rerio)


name: PTEN undergoes monoubiquitination (Mus musculus)


name: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate


name: CGRP receptor can bind calcitonin gene-related peptides (Sus scrofa)


name: motiol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 4beta-carboxyl motiol + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: indole-3-ethanol + NADP(+) = H(+) + indole-3-acetaldehyde + NADPH


name: Activation of Ca impermeable AMPA receptors (Homo sapiens)


name: 2 5'-deoxyadenosine + A + a macrocyclic archaeaol phospholipid + 2 H(+) + 2 L-methionine => a 2,3-di-O-phytanyl-sn-glycerophospholipid + AH2 + 2 S-adenosyl-L-methionine


name: SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol (Sus scrofa)


name: Beta-catenin migrates to the nucleus (Xenopus tropicalis)


name: HSD17B14 tetramer oxidises estradiol (E2) to estrone (E1) (Bos taurus)


name: 26-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Rattus norvegicus)


name: 3-methylbutanoyl-CoA + S-adenosyl-L-methionine <=> CoA + H(+) + N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine


name: NTPDase3 hydrolyzes nucleoside diphosphates (Rattus norvegicus)


name: (25R)-cholest-5-en-3beta,7alpha,26-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (25R)-cholest-5-ene-3beta,26-diol + O2 + reduced [NADPH--hemoprotein reductase]


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + H2O = (4Z,15Z)-bilirubin IXalpha + D-glucuronate + H(+)


name: AGO1,2:small RNA complexes interact with chromatin (Sus scrofa)


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Bos taurus)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA => 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: ASIC trimers:H+ transport extracellular Na+ to cytosol (Gallus gallus)


name: inorganic anion transmembrane transporter activity


name: SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Xenopus tropicalis)


name: tissue factor (TF) + activated factor VII (F7a) -> TF:F7a complex (Sus scrofa)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Gallus gallus)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-ethanolamine = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Plasmodium falciparum)


name: NAD(+) + testosterone = androst-4-ene-3,17-dione + H(+) + NADH


name: menaquinone-7 + succinate => fumarate + menaquinol-7


name: H(+) + NADH + UDP-3-oxo-alpha-D-glucose => NAD(+) + UDP-alpha-D-glucose


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Rattus norvegicus)


name: RAF is phosphorylated downstream of oncogenic RAS  (Homo sapiens)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Homo sapiens)


name: sucrose + UDP-alpha-D-galactose <=> H(+) + loliose + UDP


name: CoA + H(+) + N-octadecanoyl-taurine => octadecanoyl-CoA + taurine


name: CMP-5'-(3-aminopropyl)phosphonate + NADPH + O2 = CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate + H2O + NADP(+)


name: H(+) + N-hexacosanoylsphinganine + NADPH + O2 <=> H2O + N-(2-hydroxyhexacosanoyl)-sphinganine + NADP(+)


name: RBKS phosphorylates ribose to R5P (Canis familiaris)


name: SPHK1 binds PKR (Caenorhabditis elegans)


name: 2-oxoadipate + acetyl-CoA + H2O => (R)-dihomocitrate + CoA + H(+)


name: sGC stimulators bind sGC:NO (Sus scrofa)


name: a primary alcohol + 2 Fe(III)-[cytochrome cL] = an aldehyde + 2 Fe(II)-[cytochrome cL] + 2 H(+)


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine => 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: benzoyl-CoA + benzyl alcohol = benzyl benzoate + CoA


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)


name: D-gluconate + NADP(+) <=> 5-dehydro-D-gluconate + H(+) + NADPH


name: 2 H(+) + malonyl-CoA + methylmalonyl-CoA + octadecanoyl-CoA => 4-hydroxy-5-methyl-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Gallus gallus)


name: ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB (Homo sapiens)


name: Arachidonate is converted to HXA3/B3 by ALOX12 (Homo sapiens)


name: Translocation of YAP1 to the nucleus (Homo sapiens)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Bos taurus)


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Xenopus tropicalis)


name: ATP + H2O + hydrogenselenide => AMP + 2 H(+) + phosphate + selenophosphate


name: (20S)-protopanaxadiol + UDP-alpha-D-glucose => (20S)-ginsenoside C-K + H(+) + UDP


name: SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH (Caenorhabditis elegans)


name: Formation of the preholothymoproteasome (Mus musculus)


name: clavaminate + CO2 + H2O + succinate => 2-oxoglutarate + dihydroclavaminate + O2


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Danio rerio)


name: PIWIL4:piRNA binds nascent LINE1 pre-RNA and recruits SPOCD1, C19ORF84, DNMT3A, DNMT3L, the NURD complex, and the BAF complex (Homo sapiens)


name: Reduction of desmosterol to cholesterol (Xenopus tropicalis)


name: PIP3 binds to RhoA and activates it (Caenorhabditis elegans)


name: 4-methylamino-L-phenylalanine + S-adenosyl-L-methionine <=> 4-dimethylamino-L-phenylalanine + H(+) + S-adenosyl-L-homocysteine


name: Exocytosis of azurophil granule lumen proteins (Canis familiaris)


name: Defective HLCS does not biotinylate ACACA:Mn2+ (Homo sapiens)


name: (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADH => (1S,2S,4R)-limonene-1,2-diol + NAD(+)


name: (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate <=> 4-methylsulfanylbutyl isothionate + H(+) + sulfate


name: H2O + ipecoside => D-glucose + ipecoside aglycone


name: RNA Polymerase II Promoter Opening: First Transition (Saccharomyces cerevisiae)


name: 2-methoxy-6-all-trans-hexaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine => 6-methoxy-3-methyl-2-all-trans-hexaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylation and activation of eIF4B by activated S6K1 (Sus scrofa)


name: ATP + H2O + L-cysteine(out) <=> ADP + H(+) + L-cysteine(in) + phosphate


name: acetyl phosphate + H(+) + sulfite <=> phosphate + sulfoacetaldehyde


name: L-arogenate + oxaloacetate <=> L-aspartate + prephenate


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Caenorhabditis elegans)


name: Release of activated MAD2 from kinetochores (Gallus gallus)


name: GPIb-IX-V binds to vWF:Collagen complex (Bos taurus)


name: pelargonidin + UDP-alpha-D-glucose => pelargonidin 3-O-beta-D-glucoside + UDP


name: a thymidine(6-4)thymidine in DNA = a thymidine dimer in DNA


name: p-Y420-FYN is phosphorylated on S21 (Bos taurus)


name: a 1,2-diacyl-sn-glycerol + CDP-N,N-dimethylethanolamine = 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + CMP + H(+)


name: SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Rattus norvegicus)


name: EGFR activates PLC-gamma1 by phosphorylation (Mus musculus)


name: Class IV antihypertensives bind LTCC multimer (Sus scrofa)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Canis familiaris)


name: H2O + N-formimidoyl-L-glutamate = formamide + L-glutamate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Bos taurus)


name: SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Mus musculus)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADP(+) = 7,12-dioxo-lithocholate + H(+) + NADPH


name: 17alpha-hydroxypregnenolone 3-sulfate(out) + 2 Na(+)(out) => 17alpha-hydroxypregnenolone 3-sulfate(in) + 2 Na(+)(in)


name: ATP + glycerol => ADP + H(+) + sn-glycerol 3-phosphate


name: 20-hydroxy-leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-oxo-leukotriene B4 + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of proteins involved in G2/M transition by active Cyclin A2:Cdc2 complexes (Homo sapiens)


name: CoA + H(+) + piperyline => (E,E)-piperoyl-CoA + pyrrolidine


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 = A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Danio rerio)


name: PIAS4 SUMOylates HERC2 with SUMO1 (Homo sapiens)


name: a ribonucleoside + phosphate => a ribonucleoside 3'-phosphate + H2O


name: Activated FGFR3 binds SHC1 (Drosophila melanogaster)


name: Caspase-mediated cleavage of PKC theta (Bos taurus)


name: Alkalization of the phagosomal lumen by NOX2 (Homo sapiens)


name: 2-dehydro-3-deoxy-D-gluconate + ATP <=> 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+)


name: H(+)(out) + L-threonine(in) = H(+)(in) + L-threonine(out)


name: 2-glutaroyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2A (GRIN2A) (Xenopus tropicalis)


name: CTP(out) + UDP(in) <=> CTP(in) + UDP(out)


name: Collagen type I degradation by MMP14 (Homo sapiens)


name: Caspase mediated cleavage of APC (Xenopus tropicalis)


name: dIMP + H2O => 2'-deoxyinosine + phosphate


name: an 11-oxosteroid + H(+) + NADPH => an 11beta-hydroxysteroid + NADP(+)


name: Elongation Of The Telomeric Chromosome End (Mus musculus)


name: KCNJs transport K+ from the extracellular region to cytosol (Mus musculus)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Xenopus tropicalis)


name: USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin (Caenorhabditis elegans)


name: 3-O-methylgallate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] => Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + syringate


name: 2-oxoglutarate + H2O2 + NH4(+) => D-glutamate + H2O + O2


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: O2 + tetracenomycin F1 <=> H(+) + H2O + tetracenomycin D3


name: dihydroprecondylocarpine acetate <=> (-)-tabersonine + acetate + H(+)


name: aldosterone hemiacetal + UDP-alpha-D-glucuronate <=> aldosterone hemiacetal 18-beta-glucuronide + H(+) + UDP


name: Ca2+ influx into the post-synaptic cell (Canis familiaris)


name: (E)-2-methylpropanal oxime + O2 + reduced [NADPH--hemoprotein reductase] => 2-hydroxy-2-methylpropanenitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Schizosaccharomyces pombe)


name: Formation of the cap-binding eIF4F complex (Schizosaccharomyces pombe)


name: Formation of N-glucuronides (Bos taurus)


name: RCHY1 monoubiquitinates POLH (Bos taurus)


name: H2O + indole-3-carbaldehyde + O2 <=> H(+) + H2O2 + indole-3-carboxylate


name: an acyl-CoA + pseudotropine <=> CoA + H(+) + O-acylpseudotropine


name: N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: Assembly of the anterograde IFT train (Bos taurus)


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Xenopus tropicalis)


name: Synthesis of antigenomic RNA of human respiratory syncytial virus (Homo sapiens)


name: DVL1 is ubiquitinated by HECW1 (Bos taurus)


name: RCC1 stimulates GDP to GTP exchange on RAN (Mus musculus)


name: Unknown kinase phosphorylates RBV-MP (Homo sapiens)


name: dehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) <=> dehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)


name: an L-N,N-dihydroxypolyhomomethionine + H(+) = an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + H2O


name: DBT loss-of-function mutants don't synthesize BCAA-CoA (Homo sapiens)


name: PTPRF, PTPRS, PTPRD bind Liprins (Sus scrofa)


name: (E)-caffeoyl-CoA + 5-hydroxyanthranilate = avenanthramide C + CoA


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Danio rerio)


name: DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Rattus norvegicus)


name: asnovolin I + S-adenosyl-L-methionine => asnovolin K + S-adenosyl-L-homocysteine


name: cyanidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose) activity


name: mycothiol-dependent formaldehyde dehydrogenase activity


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)


name: CYP2A13 oxidises AFM1 to AFM1E (Danio rerio)


name: LRRC16A binds F-actin capping protein (Mus musculus)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Drosophila melanogaster)


name: Linkage of L1 with treadmilling F-actin (Caenorhabditis elegans)


name: Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Drosophila melanogaster)


name: Inhibin-A binding to TGFBR3 (Mus musculus)


name: 4-(trimethylamino)butanoyl-CoA + AMP + diphosphate => 4-(trimethylamino)butanoate + ATP + CoA


name: Addition of galactose to Core 6 glycoprotein (Danio rerio)


name: 4-guanidinobutanal + H2O + NAD(+) <=> 4-guanidinobutanoate + 2 H(+) + NADH


name: (2E,6E)-farnesyl diphosphate = beta-cubebene + diphosphate


name: Formation of allysine by LOX (Canis familiaris)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Gallus gallus)


name: MDM2 ubiquitinates JMY (Xenopus tropicalis)


name: cyclin-dependent protein kinase activating kinase activity


name: (2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate => (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O + L-glutamate


name: alpha,alpha-trehalose(out) + N(pros)-phospho-L-histidyl-[protein] => alpha,alpha-trehalose 6-phosphate(in) + L-histidyl-[protein]


name: Formation of RAD50:MRE11 complex (Schizosaccharomyces pombe)


name: PRKCI phosphorylates ELF3 (Caenorhabditis elegans)


name: Proteasome mediated degradation of COP1 (Dictyostelium discoideum)


name: SMAD7:SMURF complex binds to phosphorylated TGFBR1 (Homo sapiens)


name: TBK1/IKK epsilon complex interacts with MAVS bound TRAF3 (Homo sapiens)


name: Exocytosis of tertiary granule lumen proteins (Bos taurus)


name: Phosphorylation of TEC kinases by p-SYK (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA => a 1-acyl-sn-glycero-3-phosphocholine + an acyl-CoA


name: CHOL translocates from lysosome membrane to ER membrane (Rattus norvegicus)


name: 3-oxochola-4,17-dien-22-oyl-CoA + H2O => 17-hydroxy-3-oxochol-4-en-22-oyl-CoA


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol => a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester


name: IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Homo sapiens)


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Drosophila melanogaster)


name: nitrite transmembrane transporter activity


name: (E)-sinapate + H(+) + S-adenosyl-L-homocysteine => (E)-5-hydroxyferulate + S-adenosyl-L-methionine


name: ADP + H(+) + pyridoxine 5'-phosphate => ATP + pyridoxine


name: cholesterol + NAD(+) <=> cholest-5-en-3-one + H(+) + NADH


name: agmatine(out) + L-arginine(in) => agmatine(in) + L-arginine(out)


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Mus musculus)


name: TP53 stimulates ARID3A gene expression (Homo sapiens)


name: H2O + O-phospho-L-seryl-[myosin light chain] <=> L-seryl-[myosin light chain] + phosphate


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Mus musculus)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Sus scrofa)


name: Autophagosome maturation (Dictyostelium discoideum)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Xenopus tropicalis)


name: a very long-chain fatty acid + CoA + H(+) => a very long-chain fatty acyl-CoA + H2O


name: anthocyanin A10 + malonyl-CoA <=> anthocyanin A11 + CoA


name: CHSY1 transfers GalNAc to chondroitin (Danio rerio)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Caenorhabditis elegans)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Rattus norvegicus)


name: (S)-2-amino-6-oxohexanoate + H2O + NAD(+) = 2 H(+) + L-2-aminoadipate + NADH


name: a D-hexose + H(+) + phosphoramidate => alpha-D-hexose 1-phosphate + NH4(+)


name: (10S)-hydroxy-(12Z)-octadecenoate => (10E,12Z)-octadecadienoate + H2O


name: L-homoserine + succinyl-CoA <=> CoA + O-succinyl-L-homoserine


name: Recruitment of VAV to p-SLP-76 (Gallus gallus)


name: 2-(9Z-octadecenoyl)-glycerol + eicosanoyl-CoA = 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: RHOQ GEFs activate RHOQ (Canis familiaris)


name: 2-methylpropanal oxime + S-adenosyl-L-methionine <=> 2-methylpropanal O-methyloxime + H(+) + S-adenosyl-L-homocysteine


name: glycine(in) + H(+)(in) <=> glycine(out) + H(+)(out)


name: a quinone + shikimate => 3-dehydroshikimate + a quinol


name: 3-oxo-L-alanyl-[sulfatase] + 5'-deoxyadenosine + 2 H(+) + hydrogen sulfide + L-methionine => H2O + L-cysteinyl-[sulfatase] + S-adenosyl-L-methionine


name: LONP1 degrades mitochondrial inner membrane proteins (Dictyostelium discoideum)


name: NOTCH1 Coactivator Complex binds HES1 promoter (Homo sapiens)


name: H2O + hexadecanamide => hexadecanoate + NH4(+)


name: ATP + H2O + putrescine(out) = ADP + H(+) + phosphate + putrescine(in)


name: RAD51 gene expression is stimulated by E2F1 and inhibited by E2F6 (Homo sapiens)


name: CYP2E1 monooxygenates APAP to NAPQI (Sus scrofa)


name: A + all-trans-4,4'-diapolycopen-4-al + H2O = AH2 + all-trans-4,4'-diapolycopen-4-oate + H(+)


name: RAC1 translocates to the endoplasmic reticulum membrane (Rattus norvegicus)


name: an aliphatic sulfonate + H2O + 2 oxidized [4Fe-4S]-[ferredoxin] <=> an aldehyde + 3 H(+) + 2 reduced [4Fe-4S]-[ferredoxin] + sulfite


name: 20S,23-dihydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 20S,23,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: HDACs deacetylate p-STAT3 dimers (Drosophila melanogaster)


name: SUMOylation of NCOA1 with SUMO1 (Homo sapiens)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Rattus norvegicus)


name: PRKD1,2,3 phosphorylates CERT1-2 (Danio rerio)


name: 3,4,6-trichlorocatechol + O2 = (2Z,4E)-2,3,5-trichloromuconate + H(+)


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Mus musculus)


name: Activated FGFR4 binds FRS2 (Canis familiaris)


name: 3-oxo-(13Z)-eicosenoyl-CoA + H(+) + NADPH <=> (R)-3-hydroxy-(13Z)-eicosenoyl-CoA + NADP(+)


name: KAT5 acetylates ATM at shortened telomeres (Rattus norvegicus)


name: WLS dissociates from retromer (Xenopus tropicalis)


name: (R)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+) => D-allo-threonine + H2O + O2


name: Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)


name: (2E)-decenoyl-[ACP] + H(+) + NADH = decanoyl-[ACP] + NAD(+)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Mus musculus)


name: a triacyl-sn-glycerol + H2O => a 2,3-diacyl-sn-glycerol + a fatty acid + H(+)


name: 1,6-dihydroxyphenazine + NADPH + O2 = 1,6-dihydroxyphenazine N(5)-oxide + H2O + NADP(+)


name: 1-carboxyvinyl carboxyphosphonate + H(+) = 3-(hydrohydroxyphosphoryl)pyruvate + CO2


name: epitestosterone 17-sulfate(in) + 2 Na(+)(in) => epitestosterone 17-sulfate(out) + 2 Na(+)(out)


name: 2-methoxy-4-vinylphenol + CO2 => (E)-ferulate + H(+)


name: 2-oxoglutarate + L-homoarginine + O2 = 6-hydroxy-L-homoarginine + CO2 + succinate


name: AFG3L2 degrades mitochondrial matrix proteins (Plasmodium falciparum)


name: 2-(5-methylsulfanyl)oxopentanoate + acetyl-CoA + H2O <=> 2-(3-methylsulfanyl)propylmalate + CoA + H(+)


name: 11-oxocucurbitadienol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 11-hydroxycucurbitadienol + O2 + reduced [NADPH--hemoprotein reductase]


name: p-STAT1, p-STAT3 dissociate from IL27RA:IL12RB2 receptor (Bos taurus)


name: D-cysteine + H2O <=> H(+) + hydrogen sulfide + NH4(+) + pyruvate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base <=> a 1,2-diacyl-sn-glycerol + a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base


name: Cinaciguat binds sGC:NO (Drosophila melanogaster)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Schizosaccharomyces pombe)


name: D-threitol + NAD(+) => D-erythrulose + H(+) + NADH


name: RHOD GAPs stimulate RHOD GTPase activity (Danio rerio)


name: p100:RELB binds active NIK:p-IKKA dimer (Bos taurus)


name: KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Homo sapiens)


name: LIPC dimer hydrolyses TAG to DAG and FA (Rattus norvegicus)


name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 (Canis familiaris)


name: Fibronectin degradation by MMP14 (Bos taurus)


name: MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) (Bos taurus)


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Bos taurus)


name: RIPPLY2 binds TBX6 and recruits the 26S proteasome (Homo sapiens)


name: an acylcholine + H2O = a carboxylate + choline + H(+)


name: TGFBR2 recruits TGFBR1 (Caenorhabditis elegans)


name: a fatty acid ethyl ester + H2O => a fatty acid + ethanol + H(+)


name: Tyrosine is hydroxylated to dopa (Canis familiaris)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2


name: AMP(in) + diphosphate(in) + H(+)(in) + tetradecanoyl-CoA(in) => ATP(in) + CoA(in) + H(+)(out) + tetradecanoate(out)


name: SUMOylation of PIAS4 with SUMO1 (Danio rerio)


name: an N-acylsphing-4-enine + dTDP-alpha-D-glucose <=> a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + dTDP + H(+)


name: L-allo-threonine + NADP(+) <=> aminoacetone + CO2 + NADPH


name: Haptoglobin binds Hemoglobin (Homo sapiens)


name: SMAD3 binds STUB1 (CHIP) (Drosophila melanogaster)


name: guanosine(1405) in 16S rRNA + S-adenosyl-L-methionine <=> N(7)-methylguanosine(1405) in 16S rRNA + S-adenosyl-L-homocysteine


name: 2-AG hydrolysis to arachidonate by MAGL (Rattus norvegicus)


name: RNF144A polyubiquitinates PRKDC (Canis familiaris)


name: H(+) + N(1)-methylguanosine(2535) in 23S rRNA + S-adenosyl-L-homocysteine => guanosine(2535) in 23S rRNA + S-adenosyl-L-methionine


name: adenine(in) + H(+)(in) => adenine(out) + H(+)(out)


name: (E)-caffeate + ATP + H(+) = (E)-caffeoyl-AMP + diphosphate


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Danio rerio)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(in) + ATP + H2O = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(out) + ADP + H(+) + phosphate


name: Fibronectin degradation by CTSG (Rattus norvegicus)


name: Viral dsRNA:TLR3:TRIF complex recruits RIP1 (Homo sapiens)


name: glutathione disulfide + H(+) + NADH => 2 glutathione + NAD(+)


name: p-T68-CHEK2 autophosphorylates (Dictyostelium discoideum)


name: n H(+)(out) + L-histidine(out) => n H(+)(in) + L-histidine(in)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Rattus norvegicus)


name: (S)-corytuberine + S-adenosyl-L-methionine => magnoflorine + S-adenosyl-L-homocysteine


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: 17-dehydrostemmadenine + H2O <=> (16R)-deshydroxymethyl-stemmadenine + formate


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Mus musculus)


name: D-ribose + H2O + NADP(+) <=> D-ribonate + 2 H(+) + NADPH


name: H(+) + N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine => L-arginyl-[protein] + S-adenosyl-L-methionine


name: (E,E)-piperate + ATP + CoA <=> (E,E)-piperoyl-CoA + AMP + diphosphate


name: 2-(2,4-dichloro-5-oxo-2,5-dihydrofuryl)acetate => (2E,4E)-2,4-dichloromuconate + H(+)


name: The Immunoglobulin of the BCR binds antigen (Bos taurus)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Canis familiaris)


name: EGR1, EGR2 bind the RRAD promoter (Homo sapiens)


name: (2E)-geraniol + phosphate => (2E)-geranyl phosphate + H2O


name: ERBB2 TMD/JMD mutants bind pertuzumab (Homo sapiens)


name: [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + H(+) + NADPH + O2 = [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B + H2O + NADP(+)


name: CDK5 phosphorylates DARPP-32 on Thr75 (Gallus gallus)


name: 2 H(+) + NADPH + propanoate => H2O + NADP(+) + propanal


name: Association of procollagen type XV (Canis familiaris)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Schizosaccharomyces pombe)


name: PTPN11 binds p-Y759-IL6ST (Rattus norvegicus)


name: ZnT5 transports zinc into the golgi apparatus (Gallus gallus)


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Mus musculus)


name: 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: (3S)-hydroxytetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O


name: 9-hydroxy-octadecanoate + a 1,2-diacyl-sn-glycerol = 9-(acyloxy)-octadecanoate + a 2-acylglycerol


name: 5-hydroxy-L-arginine + CO2 + succinate => 2-oxoglutarate + L-arginine + O2


name: SUMOylation of NPM1 with SUMO1 (Rattus norvegicus)


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Canis familiaris)


name: SHC1 phosphorylation by ERBB2 heterodimers (Drosophila melanogaster)


name: 2 H2O + novapikromycin + 4 oxidized [2Fe-2S]-[ferredoxin] => 4 H(+) + narbomycin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin]


name: Inhibitors bind and inhibit highly active BRAF mutants (Homo sapiens)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds SHC1 (Homo sapiens)


name: PAK binds RAC and bPIX (Rattus norvegicus)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Sus scrofa)


name: ADH5 oxidises S-HMGSH to S-FGSH (Sus scrofa)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + CoA => an acyl-CoA + sn-glycero-3-phosphoethanolamine


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Xenopus tropicalis)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose => alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: Formation of NR-NCOR Corepressor Complex (Drosophila melanogaster)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO1 (Drosophila melanogaster)


name: acetyl-CoA + L-glutamate => CoA + H(+) + N-acetyl-L-glutamate


name: D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ (Schizosaccharomyces pombe)


name: a phenol + an aryl sulfate => a phenol + an aryl sulfate


name: DOCK180:ELMO binds CRK (Xenopus tropicalis)


name: 2-oxoglutarate + eicosanoyl-CoA + O2 => 2-hydroxyeicosanoyl-CoA + CO2 + succinate


name: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O


name: SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) (Canis familiaris)


name: 3 A + phytyl diphosphate <=> (2E,6E,10E)-geranylgeranyl diphosphate + 3 AH2


name: Connexin oligomerization in endoplasmic reticulum membrane (Danio rerio)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O => 1-hexadecanoyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: 3-O-methylgallate + O2 <=> 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + methanol


name: DSPG and CSPG translocate to the lysosome for degradation (Drosophila melanogaster)


name: PIAS1,4 SUMOylate CASP8AP2 with SUMO1 (Mus musculus)


name: Reduction of disulphide bonds in MHC II antigens (Canis familiaris)


name: 2 ATP + 2 L-glutamate + N-acetyl-L-aspartate = 2 ADP + 2 H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate + 2 phosphate


name: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate (Caenorhabditis elegans)


name: p-S133 CREB1 dimer binds the CCND1 promoter (Homo sapiens)


name: AMP + diphosphate + pentanoyl-CoA => ATP + CoA + pentanoate


name: L-cysteinyl-[protein] + S-nitroso-L-cysteinyl-[SCAN] <=> L-cysteinyl-[SCAN] + S-nitroso-L-cysteinyl-[protein]


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + L-lysyl-[protein] => a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein]


name: (1S,2S,4R)-beta-elemene + diphosphate => (2E,6E)-farnesyl diphosphate


name: TUT4,TUT7 oligouridylate mRNA (Homo sapiens)


name: H(+)(in) + L-threonine(in) <=> H(+)(out) + L-threonine(out)


name: a 5'-end dephospho-ribonucleoside-RNA + ATP => a 5'-end 5'-phospho-ribonucleoside-RNA + ADP + H(+)


name: 1,3-dihydroxy-N-methylacridone + 3 CO2 + 4 CoA + H2O => 3 H(+) + 3 malonyl-CoA + N-methylanthraniloyl-CoA


name: Protein Kinase B/Akt phosphorylates BRF1 (Gallus gallus)


name: histone H2B conserved C-terminal lysine deubiquitinase activity


name: glycine + L-asparagine => glycyl-L-asparagine + H2O


name: acetyl-CoA + tetracosanoyl-CoA = 3-oxohexacosanoyl-CoA + CoA


name: Formation of clathrin-coated vesicle (Homo sapiens)


name: Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 (Canis familiaris)


name: H(+) + NADPH + 2 phytyl diphosphate <=> (14E,18E)-lycopadiene + 2 diphosphate + NADP(+)


name: MECP2 binds GRIN2B gene promoter (Homo sapiens)


name: G-proteins dissociate from plasma-membrane estrogen receptors (Drosophila melanogaster)


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: 5-chloro-L-tryptophan + FAD + 2 H2O => chloride + FADH2 + L-tryptophan + O2


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Xenopus tropicalis)


name: 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP => 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+)


name: 4 PBGs bind to form HMB (Rattus norvegicus)


name: D-xylono-1,5-lactone + H(+) + NADH => D-xylose + NAD(+)


name: Noradrenalin synaptic vesicle docking and priming (Drosophila melanogaster)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Sus scrofa)


name: dUMP + N5,N10-methylene tetrahydrofolate => TMP + dihydrofolate (Mus musculus)


name: a ganglioside Ac-O-8-GD1a => a ganglioside Ac-O-7-GD1a


name: K63-linked polyubiquitin modification-dependent protein binding


name: atropine + H2O = H(+) + tropate + tropine


name: a 2-demethylmenaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine = 5'-deoxyadenosine + a 2-demethyl-8-methylmenaquinone + 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L-homocysteine


name: p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus (Bos taurus)


name: E-cadherin degradation by ADAM10, ADAM15 (Bos taurus)


name: Corticotropin cleavage from POMC (Rattus norvegicus)


name: Aquaporins passively transport glycerol out of cells (Homo sapiens)


name: DOLPP1 dephosphorylates DOLDP to DOLP (Dictyostelium discoideum)


name: arginine + H2O => ornithine + urea [ARG1] (Mus musculus)


name: G alpha (q) inhibits PI3K alpha (Canis familiaris)


name: (2E)-geranyl diphosphate + olivetolate => cannabigerolate + diphosphate


name: diphosphate + phyllocladan-16alpha-ol => (+)-copalyl diphosphate + H2O


name: 7,8-dihydrofolate + H(+) + NADPH => (6S)-5,6,7,8-tetrahydrofolate + NADP(+)


name: Unwinding DNA for the nascent transcript (Dictyostelium discoideum)


name: 7,8-dihydroneopterin 3'-triphosphate => 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate


name: COQ6 hydroxylates DHB (Drosophila melanogaster)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Gallus gallus)


name: ethyl 3-oxohexanoate + H(+) + NADPH => ethyl (S)-3-hydroxyhexanoate + NADP(+)


name: GDP + H(+) + lactate => H2O + N(2)-(1-hydroxy-2-oxopropyl)-GDP


name: beta-D-galactose + N-hexadecanoylsphinganine => beta-D-galactosyl-(1<->1')-N-hexadecanoylsphinganine + H2O


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate


name: SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Sus scrofa)


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Drosophila melanogaster)


name: 3,4,5-trihydroxybenzoate + O2 <=> (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + 2 H(+)


name: mature p21 RAS binds GDP (Gallus gallus)


name: CDK1 phosphorylates LBR (Rattus norvegicus)


name: AKT1 E17K mutant phosphorylates CREB1 (Homo sapiens)


name: Activation of linoleic acid to linoleoyl-CoA (Sus scrofa)


name: H2O + N-phenylhydroxylamine + 2 NADP(+) <=> 2 H(+) + 2 NADPH + nitrobenzene


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]


name: p-6Y-VEGFR2 binds PLCG1 (Rattus norvegicus)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Homo sapiens)


name: Transcription of DDIT3 (CHOP, GADD153) in response to heme deficiency (Homo sapiens)


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Xenopus tropicalis)


name: SLC34A3 cotransports Pi, 2Na+ (Homo sapiens)


name: Cho transports from the extracellular space to the cytosol (Canis familiaris)


name: 2-oxoglutarate + L-glutamate + O2 => (3R)-3-hydroxy-L-glutamate + CO2 + succinate


name: (R)-carnitine + acetoacetyl-CoA => CoA + O-3-oxobutanoyl-(R)-carnitine


name: alpha-maltopentaose + phosphate = alpha-D-glucose 1-phosphate + alpha-maltotetraose


name: (10E,12Z)-octadecadienoate + H2O <=> (10S)-hydroxy-(12Z)-octadecenoate


name: Phosphorylation of BTK by p-SYK (Gallus gallus)


name: PAK1 phosphorylates FLNA (Caenorhabditis elegans)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Saccharomyces cerevisiae)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Schizosaccharomyces pombe)


name: 2 H(+) + hexadecanoyl-[ACP] + 2 NADPH => hexadecan-1-ol + holo-[ACP] + 2 NADP(+)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ATP + L-glutamate = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + H(+) + phosphate


name: SFN dimer binds CDK1 and CCNB1 (Mus musculus)


name: H2O + monacolin L carboxylate => 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate


name: ATP + holo-[CmaA peptidyl-carrier protein] + L-alloisoleucine = AMP + diphosphate + L-alloisoleucyl-[CmaA peptidyl-carrier protein]


name: "L-allo-isoleucine--holo-[CmaA peptidyl-carrier protein] ligase"


name: abscisate(in) + ATP + H2O = abscisate(out) + ADP + H(+) + phosphate


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatrienoate


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (8R)-hydroperoxy-(9E,11Z,14Z)-eicosatrienoate


name: Excision of FapyG by OGG1 glycosylase (Plasmodium falciparum)


name: A + H2O + N(6)-methyl-L-lysyl-[protein] => AH2 + formaldehyde + L-lysyl-[protein]


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 5-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Diacylgycerol activates Protein kinase C, alpha type (Canis familiaris)


name: D-glucose 6-phosphate(in) + L-histidyl-[protein] => D-glucose(out) + N(pros)-phospho-L-histidyl-[protein]


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Homo sapiens)


name: 3-oxododecanedioyl-CoA + CoA => acetyl-CoA + decanedioyl-CoA


name: glutarate(out) + kynurenate(in) => glutarate(in) + kynurenate(out)


name: (2E)-decenoyl-CoA + H(+) + oxaloacetate <=> (4-octa-1-enyl-2,5-dioxo-2,5-dihydro-3-furanyl)acetate + CoA + H2O


name: H2O + neocasomorphin = L-isoleucine + neocasomorphin-(1-5)


name: SMURF1 binds phosphorylated PARD6A (Drosophila melanogaster)


name: (2S)-2-hydroxy-3,4-dioxopentyl phosphate => 3-hydroxy-2,4-dioxopentyl phosphate


name: H(+) + oxidized [electron-transfer flavoprotein] + undecanoyl-CoA <=> reduced [electron-transfer flavoprotein] + trans-2-undecenoyl-CoA


name: holo-[cytochrome c] <=> apo-[cytochrome c] + heme b


name: 3',5'-cyclic AMP(in) <=> 3',5'-cyclic AMP(out)


name: NAD(+) + trans,octa-cis-decaprenylphospho-beta-D-arabinofuranose => H(+) + NADH + trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose


name: Growth hormone forms dimers and oligomers (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) => a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: Activated FGFR4 binds PLCG1 (Rattus norvegicus)


name: ATXN3 deubiquitinates polyUb-PARK2 (Mus musculus)


name: a ubiquinol + dihydroxyacetone phosphate => a ubiquinone + sn-glycerol 3-phosphate


name: L-fucose(out) + 2 Na(+)(out) = L-fucose(in) + 2 Na(+)(in)


name: 2-epi-5-epi-valiolone 7-phosphate => 5-epi-valiolone 7-phosphate


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Gallus gallus)


name: AKT phosphorylates AKT1S1 (PRAS40) (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: FURIN Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis (Homo sapiens)


name: PKC phosphorylates sphingosine kinase 1 (Gallus gallus)


name: D-apionolactone + H2O <=> D-apionate + H(+)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Drosophila melanogaster)


name: 3-hydroxy-3-(4-hydroxyphenyl)propanoyl-CoA => (E)-4-coumaroyl-CoA + H2O


name: RHOT1 binds effectors at the mitochondrial outer membrane (Drosophila melanogaster)


name: Recruitment of HDAC1 by p130 (RBL2) (Canis familiaris)


name: Formation of ORC(1-5) complex (Dictyostelium discoideum)


name: Activation of Ca impermeable AMPA receptors (Caenorhabditis elegans)


name: p-4Y-PLCG1 dissociates from activated FGFR4 (Canis familiaris)


name: UCHL3, SENP8 cleave NEDD8 (Schizosaccharomyces pombe)


name: C-ter TLR7 dimer binds TLR7, TLR8 ligands (Homo sapiens)


name: PLK1 phosphorylates GORASP1 (Bos taurus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Caenorhabditis elegans)


name: Bombesin-like receptors bind bombesin homologues (Gallus gallus)


name: CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) (Homo sapiens)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Bos taurus)


name: IMPAD1 hydrolyses PAP to AMP (Mus musculus)


name: beta-D-glucose + dichloroarcyriaflavin A => 4'-demethylrebeccamycin + H2O


name: DVL2 is phosphorylated by PKC (Rattus norvegicus)


name: LIG1 binds APEX1 and PCNA at SSB (Homo sapiens)


name: 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Gallus gallus)


name: 2-oxoglutarate + L-2,4-diaminobutanoate <=> L-aspartate 4-semialdehyde + L-glutamate


name: STUB1 polyubiquitinates RUNX2 (Mus musculus)


name: 12alpha,13alpha-dihydroxyfumitremorgin C + dimethylallyl diphosphate = diphosphate + fumitremorgin B


name: 4 H(+) + N(6)-dimethyladenosine(N)/N(6)-dimethyladenosine(N+1) in rRNA + 4 S-adenosyl-L-homocysteine => adenosine(N)/adenosine(N+1) in rRNA + 4 S-adenosyl-L-methionine


name: (2E)-geranyl diphosphate => diphosphate + sabinene


name: SHP2 binds to the active receptor (Homo sapiens)


name: EPHAs bind EFNAs (Caenorhabditis elegans)


name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Homo sapiens)


name: ATM phosphorylates TP53 at S15 (Mus musculus)


name: OCT2 mediates tubular uptake of organic cations in the kidney (Danio rerio)


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate <=> CO2 + deoxyviolacein + 2 H2O + NADP(+)


name: HSF1 trimer translocates to the nucleus (Schizosaccharomyces pombe)


name: Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 (Bos taurus)


name: Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)


name: 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Rattus norvegicus)


name: a di-trans,poly-cis-dolichol + NADP(+) <=> a di-trans,poly-cis-dolichal + H(+) + NADPH


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Canis familiaris)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Rattus norvegicus)


name: PIAS1,4 SUMOylates BRCA1 with SUMO2,3 (Xenopus tropicalis)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Bos taurus)