name: Association of procollagen type III (Bos taurus)


name: RAF1 mutant complexes phosphorylate MAP2K dimer (Homo sapiens)


name: Gamma-secretase cleaves YBX1:NOTCH3 (Xenopus tropicalis)


name: H2O + O2 + spermine <=> H2O2 + NH4(+) + spermine monoaldehyde


name: H(+) + NADH + O2 + toluene => (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: USP7 deubiquitinates TP53 and counteracts MDM2 (Bos taurus)


name: GSTO dimers reduce DeHA to AscH- (Caenorhabditis elegans)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the nucleoplasm (Canis familiaris)


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Sus scrofa)


name: ARL1 recruits TGN Golgin homodimers (Drosophila melanogaster)


name: glyoxylate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Bos taurus)


name: CGA and CGB3 bind to form Human chorionic gonadotropin (hCG) (Homo sapiens)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Rattus norvegicus)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Saccharomyces cerevisiae)


name: Trafficking of GluR2-containing AMPA receptors to synapse (Mus musculus)


name: Interleukin-27 dissociates from Interleukin-27 receptor (Mus musculus)


name: SUMOylation of TDG with SUMO2,3 (Danio rerio)


name: ethyl acetate + H2O => acetate + ethanol + H(+)


name: (E)-gamma-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: XIAP dissociates from ub-TLE (Bos taurus)


name: AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Homo sapiens)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Saccharomyces cerevisiae)


name: 2 a 1-acyl-sn-glycero-3-phosphocholine <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: H(+) + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + UDP => L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: (3R,6R)-6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+) => (1R,4R)-dihydrocarvone + H(+) + NADPH + O2


name: rifampicin hemiaminal => rifampicin ortho-naphthoquinone carboxamide


name: Ferriheme is transferred from Methemoglobin to Hemopexin (Rattus norvegicus)


name: 16alpha,17beta-estriol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: Gbeta:gamma activation of PLC beta (Canis familiaris)


name: [phosphate](n) + D-glucose <=> [phosphate](n-1) + D-glucose 6-phosphate + H(+)


name: EP300 acetylates RUNX3 (Canis familiaris)


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Mus musculus)


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Mus musculus)


name: (S)-malate + a quinone = a quinol + oxaloacetate


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 18-hydroxy-11-deoxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: SUMOylation of PCNA with SUMO1 (Rattus norvegicus)


name: Homo- or heterodimerization of RAF downstream of mutant RAS (Homo sapiens)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Gallus gallus)


name: 2 Fe(III)-[cytochrome b5] + NADH = 2 Fe(II)-[cytochrome b5] + H(+) + NAD(+)


name: REV1-Pol kappa complex formation (Gallus gallus)


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Homo sapiens)


name: (2S)-2-hydroxy-4-phenylbutanenitrile => 3-phenylpropanal + hydrogen cyanide


name: a fatty acyl-CoA + phytol = a fatty acid phytyl ester + CoA


name: 11-O-acetylcyathatriol + A => 11-O-acetylcyathin A3 + AH2


name: Ubiquitinated AXIN is degraded by the proteasome (Bos taurus)


name: ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Canis familiaris)


name: MDH2 dimer dehydrogenates MAL (Xenopus tropicalis)


name: TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Canis familiaris)


name: SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 (Canis familiaris)


name: MDM2 translocates to the nucleus (Danio rerio)


name: D-serine + H2O + NAD(+) => 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Canis familiaris)


name: NTPDase2 hydrolyzes nucleoside triphosphates (Mus musculus)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Xenopus tropicalis)


name: AMP + diphosphate + NADP(+) + octanal => ATP + H(+) + NADPH + octanoate


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Canis familiaris)


name: 2 H2O + 2 L-dehydroascorbate => 2 L-ascorbate + O2


name: 5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O => 5-amino-6-(D-ribitylamino)uracil + phosphate


name: H(+) + prop-2-ynal + pyrroloquinoline quinol = prop-2-yn-1-ol + pyrroloquinoline quinone


name: [(1->3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->3)-beta-D-glucosyl](n+1) + H(+) + UDP


name: HTR3A antagonists bind HTR3A pentamer (Mus musculus)


name: H(+) + pyruvate + sulfite => (2R)-3-sulfolactate


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Dictyostelium discoideum)


name: CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 (Rattus norvegicus)


name: 2-oxoadipate + CO2 + NADH => (2R,3S)-homoisocitrate + NAD(+)


name: Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding (Homo sapiens)


name: IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Gallus gallus)


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Caenorhabditis elegans)


name: a ribonucleoside 5'-phosphate + H(+) + phosphate => a ribonucleoside 5'-diphosphate + H2O


name: MDM2 ubiquitinates JMY (Canis familiaris)


name: ATP + D-tyrosine + tRNA(Tyr) <=> AMP + D-tyrosyl-tRNA(Tyr) + diphosphate + H(+)


name: Oxytocin receptor bind oxytocin (Danio rerio)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose <=> alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Dictyostelium discoideum)


name: Inactive G alpha (i) reassociates with G beta:gamma (Bos taurus)


name: MECP2 is phosphorylated at T308 (Homo sapiens)


name: 9alpha-copalyl diphosphate <=> 9beta-pimara-7,15-diene + diphosphate


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane (Bos taurus)


name: cAMP activates EPAC2 (Caenorhabditis elegans)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Gallus gallus)


name: CHEK1 phosphorylates E2F6 (Rattus norvegicus)


name: methylammonium transmembrane transporter activity


name: an N-methylornithine lipid + H(+) + S-adenosyl-L-homocysteine => an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + S-adenosyl-L-methionine


name: "Hydron translocation or charge separation linked to oxidoreductase reactions"


name: Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA (Caenorhabditis elegans)


name: a ganglioside GT1b + CMP + H(+) => a ganglioside GD1b + CMP-N-acetyl-beta-neuraminate


name: PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex (Danio rerio)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 <=> 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O


name: IL15:IL15RA:IL2RB:JAK1:IL2RG:JAK3 translocates from the plasma membrane to the endosome (Sus scrofa)


name: (indol-3-yl)acetate + H(+) + H2O2 => H2O + indole-3-acetaldehyde + O2


name: H2O + kynurenate + L-cysteine => 2-oxo-3-sulfanylpropanoate + L-kynurenine


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Bos taurus)


name: 6-sulfo-D-quinovose + NAD(+) <=> 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H(+) + NADH


name: CYSLT2 binds LTC4,LTD4,LTE4 (Bos taurus)


name: SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Canis familiaris)


name: H(+)(in) + taurine(in) = H(+)(out) + taurine(out)


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Bos taurus)


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Drosophila melanogaster)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Rattus norvegicus)


name: RET binds GFRA1,GFRA2 (Rattus norvegicus)


name: GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Canis familiaris)


name: DAG kinase produces phosphatidic acid from DAG (Canis familiaris)


name: sulfate transmembrane transporter activity


name: [Rab1 protein]-L-tyrosine + AMP + H(+) => [Rab1 protein]-O(4)-(5'-adenylyl)-L-tyrosine + H2O


name: PTPN18 dephosphorylates ERBB2 at Y1196, Y1112 and Y1248 (Canis familiaris)


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Homo sapiens)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Gallus gallus)


name: PANK4 hydrolyzes PPANT to pantetheine (Homo sapiens)


name: [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + AH2 + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + A + AMP + H(+) + L-cysteinyl-[cysteine desulfurase]


name: Association of Nek2A with MCC:APC/C (Homo sapiens)


name: Activated FGFR4 phosphorylates SHC1 (Drosophila melanogaster)


name: H(+) + N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine => L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine


name: (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + CO2 + CoA


name: H(+) + H2O + S-adenosyl-L-homocysteine = NH4(+) + S-inosyl-L-homocysteine


name: 11-O-acetylcyathatriol + UDP-alpha-D-glucose = erinacine Q2 + H(+) + UDP


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Bos taurus)


name: WWTR1:p-2S-SMAD2,3:SMAD4 binds SMAD7 gene promoter (Homo sapiens)


name: Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)


name: TFIIS-mediated recovery of elongation from arrest (Mus musculus)


name: L-homocysteine + S-methyl-L-methionine <=> H(+) + 2 L-methionine


name: CoA + H(+) + N-(9Z-hexadecenoyl)-glycine => (9Z)-hexadecenoyl-CoA + glycine


name: ANKLE2 binds VRK1,(VRK2) (Gallus gallus)


name: (25S)-3beta-hydroxy-5-cholestenoate + ATP + CoA => (25S)-3beta-hydroxy-5-cholestenoyl-CoA + AMP + diphosphate


name: 2',2'-dihydroxy-2-oxospirilloxanthin => 2,2'-dioxospirilloxanthin + H2O


name: RHOQ binds effectors at the plasma membrane (Sus scrofa)


name: SETD6 methylates RELA in the NFkB complex (Mus musculus)


name: Fe(III)-di(C-5-deoxy-beta-D-glucosyl)-enterobactin + H2O => Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+)


name: Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen (Bos taurus)


name: RABGGTA binds RABGGTB (Plasmodium falciparum)


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Sus scrofa)


name: decane + O2 + reduced [NADPH--hemoprotein reductase] <=> 3-decanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (11R)-carlactonoate + S-adenosyl-L-methionine = (11R)-methyl carlactonoate + S-adenosyl-L-homocysteine


name: [protein]-D-aspartate + S-adenosyl-L-methionine => [protein]-D-aspartate methyl ester + S-adenosyl-L-homocysteine


name: phosphatidylinositol phospholipase C activity


name: BTNL2 binds activated T cells surface (Canis familiaris)


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Canis familiaris)


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Plasmodium falciparum)


name: SLCO4C1 mediates the transport of digoxin (Xenopus tropicalis)


name: (21S)-21-acetyl-1-hydroxy-apo-melianone + acetyl-CoA => acetate + CoA + epi-neemfruitin B + H(+)


name: GSDME (1-270) binds cardiolipin (Mus musculus)


name: NFkB complex translocates from the cytosol to the nucleus (Mus musculus)


name: butanoyl-CoA + NAD(+) => (2E)-butenoyl-CoA + H(+) + NADH


name: TOPORS SUMOylates SIN3A with SUMO1 (Gallus gallus)


name: Migfilin interacts with VASP (Drosophila melanogaster)


name: AXIN is phosphorylated in the destruction complex (Sus scrofa)


name: H(+)(in) + uridine(in) <=> H(+)(out) + uridine(out)


name: PI3-kinase binds to the active receptor (Canis familiaris)


name: AP-1:DSP1:STAT92E complex recruits RPD3 and represses transcription of the REL-68 target gene (Drosophila melanogaster)


name: a tertiary amine + S-adenosyl-L-methionine => a methylated tertiary amine + H(+) + S-adenosyl-L-homocysteine


name: ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)


name: XDH oxidises 6MP to 6TU (Canis familiaris)


name: (6E)-8-hydroxygeraniol + NAD(+) <=> (6E)-8-oxogeraniol + H(+) + NADH


name: H(+) + isopentenyl phosphate + phosphate => H2O + isopentenyl diphosphate


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Rattus norvegicus)


name: NF-kB migrates to the nucleus and turns on transcription (Mus musculus)


name: Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA (Bos taurus)


name: a 1,2-diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base => a 1,2-diacyl-3-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base


name: JMJD1C demethylates H3K9 mono- and di-methylation (Sus scrofa)


name: PGRMC2:Hemes translocate to the nucleus (Dictyostelium discoideum)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Gallus gallus)


name: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O


name: (E)-4-coumaroyl-CoA + (E)-feruloylacetyl-CoA + H2O <=> CO2 + 2 CoA + demethoxycurcumin


name: H2O + N-eicosanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> (9Z)-octadecenoate + H(+) + N-eicosanoyl-sn-glycero-3-phosphoethanolamine


name: acetyl-CoA + choline = acetylcholine + CoA


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Bos taurus)


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Canis familiaris)


name: ATP + H(+) + nonanoate <=> diphosphate + nonanoyl-AMP


name: 2-oxoglutarate + dodecyl sulfate + O2 => CO2 + dodecanal + H(+) + succinate + sulfate


name: GDP-beta-L-fucose + L-seryl-[EGF-like domain protein] = 3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + GDP + H(+)


name: a triacylglycerol + all-trans-retinol = a 1,3-diacylglycerol + an all-trans-retinyl ester


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)


name: granulocyte colony-stimulating factor receptor activity


name: PMS2 variants-defective DNA mismatch repair (Homo sapiens)


name: mycothiol conjugates with electrophilic xenobiotic (Mycobacterium tuberculosis)


name: H(+) + L-erythrulose + NADH => L-threitol + NAD(+)


name: acetyl-CoA + pyruvate => (3S)-citramalyl-CoA


name: JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Canis familiaris)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Gallus gallus)


name: H(+) + hexadecanoate + NADPH + O2 = 14-hydroxyhexadecanoate + H2O + NADP(+)


name: a (2R)-2-hydroperoxy fatty acid => a 1,2-saturated fatty acid + O2


name: Autocatalytic activation of bound proMMP2 (Caenorhabditis elegans)


name: p-Y407-YAP1 translocates from the cytosol to the nucleoplasm (Gallus gallus)


name: an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP => ADP + an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: NADP(+) + octanoyl-CoA => (2E)-octenoyl-CoA + H(+) + NADPH


name: dIMP + H2O <=> 2'-deoxyinosine + phosphate


name: CDK2 phosphorylates RBBP8 (Schizosaccharomyces pombe)


name: (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase] => 8-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-hydroxy-3-all-trans-decaprenylbenzoate + H(+) = 2-all-trans-decaprenylphenol + CO2


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Sus scrofa)


name: norajmaline + S-adenosyl-L-methionine => 4-methylnorajmaline + H(+) + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + butanoyl-CoA + O2 => 2-hydroxybutanoyl-CoA + CO2 + succinate


name: CoA + H(+) + O-acylpseudotropine => an acyl-CoA + pseudotropine


name: (2S)-naringenin 7-O-beta-D-glucoside + H2O <=> (2S)-naringenin + beta-D-glucose


name: a very-long-chain (3S)-hydroxyacyl-CoA + NAD(+) <=> a very-long-chain 3-oxoacyl-CoA + H(+) + NADH


name: Chloride ion and N-acyl group react to chloramide (Homo sapiens)


name: STK11 (LKB1) phosphorylates NUAK1 (Sus scrofa)


name: Clusterin binds C5b-C7, C8, C9 (Bos taurus)


name: MLCL is acylated to CL by HADH (IM) (Rattus norvegicus)


name: (R)-benzodiazepinedione + dimethylallyl diphosphate => (2R,3S,11R)-aszonalenin + diphosphate


name: NADPH + pentaerythritol tetranitrate <=> NADP(+) + nitrite + pentaerythritol trinitrate


name: H(+) + NADPH + O2 + octan-3-one => ethyl hexanoate + H2O + NADP(+)


name: SPRY2 is serine phosphorylated in response to MAPK activation (Bos taurus)


name: Activation and dimerization of c-JUN in the nucleus (Gallus gallus)


name: Binding of Grb10 to the insulin receptor (Bos taurus)


name: GSTZ1 isomerizes 4-MAA (Canis familiaris)


name: 4-sulfomuconolactone + H2O <=> 2 H(+) + maleylacetate + sulfite


name: biuret + H2O => NH4(+) + urea-1-carboxylate


name: ligase activity, forming nitrogen-metal bonds


name: VEGFA-165 dimer binds VEGFR2 dimer (Gallus gallus)


name: Association of Cyclin A with the APC/C (Rattus norvegicus)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Canis familiaris)


name: Clustering of Integrin alphaIIb beta3 complexes (Canis familiaris)


name: Glucosylation of collagen propeptide hydroxylysines (Xenopus tropicalis)


name: Formation of the SCF-FBXL7 complex (Mus musculus)


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Mus musculus)


name: 32-hydroxyeburicol + O2 + reduced [NADPH--hemoprotein reductase] = 32-oxoeburicol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Autophagosome maturation (Plasmodium falciparum)


name: 4-methylpentan-2-one + hydrogen cyanide = (2S)-2-hydroxy-2,4-dimethylpentanenitrile


name: 1-(beta-D-galactosyl)-N-dodecanoylsphing-4-enine + cholesterol <=> cholesteryl 3-beta-D-galactoside + N-dodecanoylsphing-4-enine


name: MDM2 translocates to the cytosol (Gallus gallus)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Rattus norvegicus)


name: 11-hydroxyferruginol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 11-hydroxysugiol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: MET bound PI3K generates PIP3 (Caenorhabditis elegans)


name: CO2 + succinate + TRIBOA beta-D-glucoside => 2-oxoglutarate + DIBOA beta-D-glucoside + O2


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Danio rerio)


name: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O


name: 4-methylpentanoyl-CoA + AMP + diphosphate => 4-methylpentanoate + ATP + CoA


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Mus musculus)


name: PKA phosphorylates GLI3 (Rattus norvegicus)


name: H2O + N(1)-(3-aminopropyl)agmatine = spermidine + urea


name: LIPT2 transfers octanoyl group to GCSH (Rattus norvegicus)


name: PIAS1 binds p-STAT1 dimer (Gallus gallus)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Xenopus tropicalis)


name: MET phosphorylates PTK2 (Caenorhabditis elegans)


name: (3R)-hydroxydecanoyl-[ACP] + NADP(+) => 3-oxodecanoyl-[ACP] + H(+) + NADPH


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Drosophila melanogaster)


name: H2O + N-acyl-sn-glycero-3-phosphoethanolamine = an N-acylethanolamine + H(+) + sn-glycerol 3-phosphate


name: acetylsalicylate + L-seryl-[protein] => O-acetyl-L-seryl-[protein] + salicylate


name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Mus musculus)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: PROT mediates L-proline uptake (Drosophila melanogaster)


name: ACAD11 dehydrogenates BH-CoA (Xenopus tropicalis)


name: PNPLA7 hydrolyzes LysoPtdCho (Homo sapiens)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Homo sapiens)


name: RHOH binds effectors at the plasma membrane (Rattus norvegicus)


name: Dissociation of the P2Y purinoceptor 12:Gi complex (Bos taurus)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Mus musculus)


name: H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + 2 H2O = 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + 2 chloride + 2 H(+)


name: CYP11A1 cleaves 20a,22b-DHCHOL (Sus scrofa)


name: succinate(in) + urate(out) => succinate(out) + urate(in)


name: IFNAR1:TYK2 binds TYK2 inhibitors (Rattus norvegicus)


name: an NDP-alpha-D-glucose + D-glucose => a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H(+)


name: MAPKs phosphorylate ETS1 and ETS2 (Canis familiaris)


name: SREBP1A,2 binds the MVK promoter (Homo sapiens)


name: decanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] <=> CoA + H(+) + N(6)-decanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: ATP + 2 N-(3-carboxypropanoyl)-N-hydroxyputrescine <=> AMP + diphosphate + H(+) + pre-putrebactin


name: 11a-hydroxytetracycline + H2O + NADP(+) => H(+) + NADPH + O2 + tetracycline


name: CoA + O-2,6-dimethylheptanoyl-(R)-carnitine => (R)-carnitine + 2,6-dimethylheptanoyl-CoA


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Saccharomyces cerevisiae)


name: Release Of ADP From Myosin (Gallus gallus)


name: REG3A,REG3G binds bacterial peptidoglycan (Drosophila melanogaster)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Homo sapiens)


name: a diacylglycerol + an all-trans-retinyl ester => a triacylglycerol + all-trans-retinol


name: Cannabinoid receptors can bind cannabinoids (Sus scrofa)


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Homo sapiens)


name: acarbose + ATP => acarbose 7(IV)-phosphate + ADP + H(+)


name: RAP1A exchanges GDP for GTP (Caenorhabditis elegans)


name: E-cadherin degradation by MMP9, KLK7 (Sus scrofa)


name: 2-methylpropan-1-amine + H2O + NAD(+) <=> 2-methylpropanal + H(+) + NADH + NH4(+)


name: UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Homo sapiens)


name: Ca2+ influx through voltage gated Ca2+ channels (Rattus norvegicus)


name: AKT1 E17K mutant binds PIP2 (Homo sapiens)


name: 1-phenylpropan-1-one + L-alanine => 1-phenylpropylamine + pyruvate


name: RHAG transports CO2 from cytosol to extracellular region (Homo sapiens)


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Canis familiaris)


name: Kinesin-1 is a heterotetramer (Mus musculus)


name: Caspase-mediated cleavage of MASK (Mus musculus)


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Schizosaccharomyces pombe)


name: PTPN7 binds p-T,Y-MAPK (Dictyostelium discoideum)


name: SUMOylation of NPM1 with SUMO2,3 (Rattus norvegicus)


name: (3R)-hydroxytetradecanoyl-[ACP] + NADP(+) => 3-oxotetradecanoyl-[ACP] + H(+) + NADPH


name: oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] (Gallus gallus)


name: 4-farnesyl-3,5-dihydroxy-6-methylphthalide + AH2 + 2 O2 <=> (4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + A + acetone + H(+) + H2O


name: NR3C2 binds fludrocortisone (Gallus gallus)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Dictyostelium discoideum)


name: Phosphorylation of SHP2 by SFKs (Xenopus tropicalis)


name: a monocarboxylate + NH4(+) => a monocarboxylic acid amide + H2O


name: ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)


name: RUNX1 binds PRMT1 (Caenorhabditis elegans)


name: Isomerization of 25(R) THCA-CoA to 25(S) THCA-CoA (Homo sapiens)


name: ATP + CoA + hexadecanedioate <=> AMP + diphosphate + hexadecanedioyl-CoA


name: H(+)(out) + L-arabinose(in) = H(+)(in) + L-arabinose(out)


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Mus musculus)


name: GGPS1 hexamer transfers IPPP to GPP (Xenopus tropicalis)


name: glutaryl-CoA + succinate => glutarate + succinyl-CoA


name: STARD7 transports Q10 to plasma membrane (Drosophila melanogaster)


name: Autophosphorylation of PAK1 (Gallus gallus)


name: Caspase-1 active tetramer formation (Homo sapiens)


name: 2-phenylethylamine + H2O + O2 => 2-phenylacetaldehyde + H2O2 + NH4(+)


name: KRAS4B recycles to the plasma membrane (Caenorhabditis elegans)


name: a 1-acyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: D-fructuronate(out) + H(+)(out) => D-fructuronate(in) + H(+)(in)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(out) + ADP + H(+) + phosphate => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate(in) + ATP + H2O


name: DNA polymerase alpha:primase binds at the origin (Sus scrofa)


name: p100:RELB binds active NIK:p-IKKA dimer (Rattus norvegicus)


name: (R)-4-dehydropantoate + H(+) + NADH => (R)-pantoate + NAD(+)


name: IGF1,2:IGF1R autophosphorylates (Homo sapiens)


name: PKA phosphorylates MAPKAPK5 (Rattus norvegicus)


name: RHOT1 hydrolyzes GTP (Dictyostelium discoideum)


name: SUMOylation of DDX5 with SUMO1 (Mus musculus)


name: Phosphorylation of DCC by Fyn (Drosophila melanogaster)


name: Degradation of newly synthesized ApoB-48 (Homo sapiens)


name: lithocholate + UDP-alpha-D-glucuronate = lithocholoyl-24-O-(beta-D-glucuronate) + UDP


name: 3 H(+) + hexadecanoyl-CoA + 3 malonyl-CoA => 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: 2 L-cysteine + NAD(+) => H(+) + L-cystine + NADH


name: carnosine(in) + H(+)(in) => carnosine(out) + H(+)(out)


name: 4'-demethylrebeccamycin + H2O = beta-D-glucose + dichloroarcyriaflavin A


name: Phosphorylation of ChREBP at Serine 556 by AMPK (Homo sapiens)


name: PP2A methylation by LCMT1 (Mus musculus)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)


name: (+)-copalol + diphosphate => (+)-copalyl diphosphate + H2O


name: prostaglandin B1 + UDP-alpha-D-glucuronate => 15-O-(beta-D-glucuronosyl)-prostaglandin B1 + H(+) + UDP


name: a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + an N-acylethanolamine + H(+) => H2O + N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine


name: ADP + H(+) + phosphate + thiosulfate(in) => ATP + H2O + thiosulfate(out)


name: RUNX2 gene expression from distal (P1) promoter is inhibited by NKX3-2, MSX2 and RUNX2-P1, and stimulated by DLX5,(DLX6) (Homo sapiens)


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Caenorhabditis elegans)


name: 3-(indol-3-yl)lactate + NAD(+) => H(+) + indole-3-pyruvate + NADH


name: Axonal transport of NGF:Trk complexes (Bos taurus)


name: LTA4 is hydolysed to LTB4 by LTA4H (Caenorhabditis elegans)


name: H(+) + NADH + pyridoxal => NAD(+) + pyridoxine


name: PRKCI phosphorylates NFE2L2 (Rattus norvegicus)


name: (S)-1-phenylethylamine + H2O + NAD(+) => acetophenone + H(+) + NADH + NH4(+)


name: an anthocyanidin 3-O-beta-D-glucoside 5-O-beta-D-[(6-O-(E)-4-coumaroyl)glucoside] + CoA => (E)-4-coumaroyl-CoA + an anthocyanidin 3,5-di-O-beta-D-glucoside


name: O2 + octanedioyl-CoA = (2E)-octenedioyl-CoA + H2O2


name: D-glucose 6-phosphate + glycerol => D-glucose + sn-glycerol 3-phosphate


name: Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)


name: an aldehyde + hydrogen cyanide => a monosubstituted aliphatic (S)-hydroxynitrile


name: STING binds TRIM32 or TRIM56  (Bos taurus)


name: (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP-alpha-D-glucuronate => (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP


name: WHSC1 binds DNA DSBs (Saccharomyces cerevisiae)


name: Cleaved KMT2A dimers translocate to the nucleus (Sus scrofa)


name: p-S295-PDE3B hydrolyses cAMP to AMP (Rattus norvegicus)


name: H2O + S-sulfosulfanyl-L-cysteinyl-[SoxY protein] = H(+) + S-sulfanyl-L-cysteinyl-[SoxY protein] + sulfate


name: (2E,6E)-farnesyl diphosphate + H(+) + NADPH + O2 = (2E,6E)-omega-hydroxy-farnesyl diphosphate + H2O + NADP(+)


name: NDUF subunits bind to form the IP subcomplex (Bos taurus)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Xenopus tropicalis)


name: ATM phosphorylates TP53 at S15 (Drosophila melanogaster)


name: PIAS1 SUMOylates THRB with SUMO1 (Gallus gallus)


name: RHOD binds effectors at the Golgi membrane (Rattus norvegicus)


name: a primary linear alkyl sulfate ester + H2O <=> a primary alcohol + H(+) + sulfate


name: CYP26A1,B1 4-hydroxylate atRA (Danio rerio)


name: CYP27A1 27-hydroxylates CHOL (Rattus norvegicus)


name: ERBB4s80 forms a complex with estrogen receptor ESR1 (Drosophila melanogaster)


name: (+)-piperitol + O2 + reduced [NADPH--hemoprotein reductase] <=> (+)-sesamin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Caenorhabditis elegans)


name: SYS1 binds AcM-ARFRP1 (Saccharomyces cerevisiae)


name: a long-chain fatty acyl-CoA + acetyl-CoA <=> a long-chain 3-oxo-fatty acyl-CoA + CoA


name: Formation of NR-NCOR Corepressor Complex (Canis familiaris)


name: MIR137 gene expression is inhibited by MECP2 and SOX2 (Homo sapiens)


name: Autophagosome maturation (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphate


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O = 2-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: uridine(54/55) in tRNA => pseudouridine(54/55) in tRNA


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: GTP + pyruvate => GDP + H(+) + phosphoenolpyruvate


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: SLC2A5 transports fructose from extracellular region to cytosol (Bos taurus)


name: PDE12 cleaves 2'-5' oligoadenylates  (Drosophila melanogaster)


name: Ligands bind L-selectin (Canis familiaris)


name: sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP (Gallus gallus)


name: H2O + sphing-4-enine-phosphocholine <=> H(+) + phosphocholine + sphing-4-enine


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Rattus norvegicus)


name: Some HSPGs are secreted to the plasma membrane (Canis familiaris)


name: Carboxypeptidase E cleaves Insulin(25-56) to yield Insulin(25-54) (Homo sapiens)


name: ARL2:GTP bind PDE6D on KRAS4B (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol = a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: SREBP1A,2 binds the SC5DL promoter (Homo sapiens)


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Mus musculus)


name: asc-omegaC5-CoA + O2 = asc-omegaDeltaC5-CoA + H2O2


name: Formation of collagen networks (Homo sapiens)


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Homo sapiens)


name: AMP + ATP <=> ADP + ADP [AK2] (Dictyostelium discoideum)


name: OTUD7A hydrolyses K11diUb (Gallus gallus)


name: cholestanol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-26-hydroxycholestanol + H2O + 2 oxidized [adrenodoxin]


name: 2-butyloctan-1-ol + H(+) + sulfate => 2-butyloctyl sulfate + H2O


name: H(+) + N(1)-methylpseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-homocysteine => pseudouridine(914) in M. jannaschii 16S rRNA + S-adenosyl-L-methionine


name: (R)-mandelamide + H2O => (R)-mandelate + NH4(+)


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Rattus norvegicus)


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Caenorhabditis elegans)


name: dihydroalstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine


name: mature p21 RAS binds GDP (Rattus norvegicus)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Caenorhabditis elegans)


name: AFG3L2 binds mitochondrial inner membrane proteins (Rattus norvegicus)


name: ESTG binds ESR1:chaperone complex (Mus musculus)


name: Formation of hydroxylysyl-pyrrole cross-links (Sus scrofa)


name: D-serine(out) + L-alanine(in) = D-serine(in) + L-alanine(out)


name: (2R)-3-phosphoglycerate + [phosphate](n+1) => (2R)-3-phospho-glyceroyl phosphate + [phosphate](n)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Homo sapiens)


name: alanine transmembrane transporter activity


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Caenorhabditis elegans)


name: Caspase-mediated cleavage of E-Cadherin (Gallus gallus)


name: dimethylallyl diphosphate + harmol <=> 6-(3-dimethylallyl)harmol + diphosphate


name: Inactivation of Wee1 kinase (Rattus norvegicus)


name: 1'-hydroxyversicolorone + H(+) + NADPH + O2 = (2S,3S)-versiconal hemiacetal acetate + H2O + NADP(+)


name: Carbonic anhydrase dehydrates bicarbonate (plasma membrane) (Homo sapiens)


name: BESTs transport cytosolic Cl- to extracellular region (Mus musculus)


name: Release of GABA at the synapse (Rattus norvegicus)


name: L-homocysteine + succinate => hydrogen sulfide + O-succinyl-L-homoserine


name: Mg-protoporphyrin IX + S-adenosyl-L-methionine <=> Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine


name: 2-deoxystreptamine + UDP-alpha-D-glucose => 2'-deamino-2'-hydroxyparomamine + H(+) + UDP


name: (S)-3-methyl-2-oxopentanoate + H(+) => 2-methylbutanal + CO2


name: 10-carboxy-13-deoxydaunorubicin + H(+) + methanol => 4-O-methylrhodomycin D + H2O


name: H(+) + NADH + scyllo-inosose => myo-inositol + NAD(+)


name: ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) (Homo sapiens)


name: NPAS4 binds MDM2 gene promoter (Homo sapiens)


name: (R)-(3-(acetylhydroxyamino)-2-hydroxypropyl)phosphonate + CO2 + succinate => 2-oxoglutarate + 3-(N-acetyl-N-hydroxy)aminopropylphosphonate + O2


name: KIAA0101 double monoubiquitination (Gallus gallus)


name: decan-1-ol + O2 + reduced [NADPH--hemoprotein reductase] => 1,7-decanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Plasmodium falciparum)


name: 2-oxoglutaramate + UDP-alpha-D-kanosamine => L-glutamine + UDP-3-oxo-alpha-D-glucose


name: 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase] => cholesta-5,7-dien-3beta,25-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SUMO-CRABP2:atRA translocates from cytosol to nucleus (Bos taurus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> beta-geranylfarnesene + diphosphate


name: LONP1 degrades mitochondrial inner membrane proteins (Drosophila melanogaster)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)


name: histone H4K20 monomethyltransferase activity


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Mus musculus)


name: EGFR binds EPS15, EPN1, EPS15L1 (Canis familiaris)


name: 11-hydroperoxy-(8Z,12E,14Z)-eicosatrienoate => (8Z,11Z,14Z)-eicosatrienoate + O2


name: all-trans-antheraxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => all-trans-violaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Homo sapiens)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Schizosaccharomyces pombe)


name: (5R)-albaflavenol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> albaflavenone + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: GALK1 phosphorylates Gal to Gal1P (Mus musculus)


name: GPI dimer isomerizes Fru(6)P to G6P (Gallus gallus)


name: (R)-carnitine(out) + O-octanoyl-(R)-carnitine(in) <=> (R)-carnitine(in) + O-octanoyl-(R)-carnitine(out)


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Schizosaccharomyces pombe)


name: NEIL1 translocates to the nucleus (Gallus gallus)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Caenorhabditis elegans)


name: Expression of PCK1 regulated by NR1H3 (Homo sapiens)


name: apo-[alkylcobalamin reductase] + glutathione + methylcob(III)alamin <=> cob(I)alamin-[alkylcobalamin reductase] + H(+) + S-methyl glutathione


name: a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol => a di-trans,poly-cis-dolichyl phosphate + an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + H(+)


name: CYP3A4 monooxygenates ATV to 2-OH-ATV (Homo sapiens)


name: cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-cholest-5-ene-3beta,26-diol + H2O + 2 oxidized [adrenodoxin]


name: 5-(carboxymethyl)uridine(34) in tRNA + S-adenosyl-L-methionine => 5-(2-methoxy-2-oxoethyl)uridine(34) in tRNA + S-adenosyl-L-homocysteine


name: TRAF6 oligomer autoubiquitinates (Mus musculus)


name: CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density (Homo sapiens)


name: CALM1:Ca2+ binds CNG channel (Rattus norvegicus)


name: Hydroperoxy reductase reduces 7(S)-Hp-17(R)-HDHA to AT-RvD5 (Homo sapiens)


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: 4-carboxy-2-hydroxy-cis,cis-muconate + H2O => 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate


name: Factor H displaces Bb (Xenopus tropicalis)


name: H2O + N-methyl-2-methylpropanamine + NAD(+) = 2-methylpropanal + H(+) + methylamine + NADH


name: 2-hydroxyoctadecanoate + O2 = 2-oxooctadecanoate + H2O2


name: (3R)-[(10S)-11-epoxyfarnesyl]-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate + H(+) => asnovolin H


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Gallus gallus)


name: Phosphorylation of PDPK1 on serine-241 (Plasmodium falciparum)


name: PI is exchanged with PC by PITPNB (Bos taurus)


name: ATP + L-fuculose <=> ADP + H(+) + L-fuculose 1-phosphate


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Bos taurus)


name: GAL3ST1 transfers sulfate to GalCer,LacCer (Rattus norvegicus)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Canis familiaris)


name: 2-(3-methylsulfanyl)propylmalate + CoA + H(+) => 2-(5-methylsulfanyl)oxopentanoate + acetyl-CoA + H2O


name: 16-epivellosimine + acetyl-CoA => CoA + vinorine


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-2-hydroxynaringenin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC (Sus scrofa)


name: 3-oxochola-1,4-dien-22-oate + H(+) + NADH + O2 <=> 9alpha-hydroxy-3-oxochola-1,4-dien-22-oate + H2O + NAD(+)


name: p-PKR dimer phosphorylates MKK6 (Rattus norvegicus)


name: ATP + H2O + L-aspartate + L-glutamine <=> AMP + diphosphate + H(+) + L-asparagine + L-glutamate


name: IL12A:IL12B translocates from ER lumen to Golgi (Homo sapiens)


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Mus musculus)


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-pyrethrolone = CoA + pyrethrin I


name: E2F7 and E2F8 homo- and heterodimers bind the E2F1 gene promoter (Homo sapiens)


name: 2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glutathione = (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Homo sapiens)


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Sus scrofa)


name: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) <=> (S)-allantoin + CO2


name: (S)-dihydroorotate + ubiquinone-8 = orotate + ubiquinol-8


name: Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Drosophila melanogaster)


name: TRAF2,6 ubiquitinates NLRC5 (Rattus norvegicus)


name: Complement factor B binds to surface-bound C3b fragment (Gallus gallus)


name: 3-oxo-(7Z-hexadecenoyl)-CoA + CoA = (5Z)-tetradecenoyl-CoA + acetyl-CoA


name: USP7 deubiquitinates MDM2 (Rattus norvegicus)


name: a ganglioside GT1c + N-acetylneuraminate => a ganglioside GQ1c + H2O


name: USP9X (FAM) deubiquitinates SMAD4 (Bos taurus)


name: Movement of clathrin coated vesicles into early endosome (Drosophila melanogaster)


name: (9Z,12Z,15Z)-octadecatrienamide + H2O = (9Z,12Z,15Z)-octadecatrienoate + NH4(+)


name: EPCAM binds itself to form homotypic cell adhesion (Sus scrofa)


name: Y693-STAT4 dimer translocates to the nucleus (Mus musculus)


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Caenorhabditis elegans)


name: P2Y14 receptor can bind to UDP-glucose (Canis familiaris)


name: YWHAZ binds p-CBY:CTNNB1 (Xenopus tropicalis)


name: SPRY2 translocates to the plasma membrane (Sus scrofa)


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Gallus gallus)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Homo sapiens)


name: a medium-chain 2,3-saturated fatty acyl-CoA + O2 => a medium-chain (2E)-enoyl-CoA + H2O2


name: tetrapeptide transmembrane transporter activity


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O <=> 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate


name: Caspase-mediated cleavage of MST3 (Gallus gallus)


name: N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine => guanosine(527) in 16S rRNA + S-adenosyl-L-methionine


name: (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate => (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2


name: 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide => 1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O


name: decan-1-ol + hexadecanoyl-CoA <=> CoA + decanyl hexadecanoate


name: AZD1979 + H2O <=> AZD1979 oxetane hydrolysis product + H(+)


name: MITF-M-dependent ATP6V1H gene expression (Homo sapiens)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Danio rerio)


name: phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] => (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit]


name: Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha  (Bos taurus)


name: Degradation of multiubiquitinated Nek2A (Canis familiaris)


name: GBF1 stimulates nucleotide exchange on ARF (Saccharomyces cerevisiae)


name: eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Danio rerio)


name: 3-chlorocatechol + NAD(+) + nitrite => 1-chloro-2-nitrobenzene + NADH + O2


name: Active FLT3 binds to GRAP2 (Mus musculus)


name: CBL ubiquitinates FRS2 and FGFR4 (Sus scrofa)


name: Arachidonate is oxidised to PGG2 by PTGS1 (Bos taurus)


name: The acetyl group from acetyl-CoA is transferred to the NAT2 (Danio rerio)


name: dimethyl sulfoxide + H2O + NAD(+) <=> dimethyl sulfone + H(+) + NADH


name: Activation of Ca permeable AMPA receptors (Bos taurus)


name: (1R)-(1-hydroxyethyl)phosphonate + O2 <=> acetate + 2 H(+) + phosphate


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Homo sapiens)


name: pseudouridine in snRNA => uridine in snRNA


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Xenopus tropicalis)


name: BTN2A2 binds T cell surface (Xenopus tropicalis)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + H(+) + malonyl-CoA = (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + CoA


name: S1PR1 binds S1PR1 agonists (Danio rerio)


name: bacterioruberin <=> H2O + monoanhydrobacterioruberin


name: p-Y705-STAT3, p-Y641-STAT6 dimerise (Caenorhabditis elegans)


name: 1,4-benzoquinone + H2O + NADP(+) + nitrite => 4-nitrophenol + H(+) + NADPH + O2


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Homo sapiens)


name: 15-demethylaclacinomycin T + AH2 + O2 = 10-decarboxymethylaclacinomycin T + A + CO2 + H2O


name: Binding of STAT1 to p-IFNGR1 (Bos taurus)


name: ABC-type glycerol-3-phosphate transporter activity


name: ATP + creatine => ADP + H(+) + N-phosphocreatine


name: Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S (Homo sapiens)


name: REG3A oligomerize to form a pore complex (Rattus norvegicus)


name: MAOB:FAD oxidatively deaminates TYR (Rattus norvegicus)


name: (3R)-hydroxydocosanoyl-CoA + NAD(+) = 3-oxodocosanoyl-CoA + H(+) + NADH


name: Bcl-2 and Bcl-XL bind NLRP1 (Canis familiaris)


name: PRMT6 methylates histone H2A arginine-30 (H2AR29) (Sus scrofa)


name: CoA + H(+) + N-hexadecanoylsphinganine => hexadecanoyl-CoA + sphinganine


name: CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Canis familiaris)


name: endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters


name: "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters"


name: adenosine in rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine in rRNA + S-adenosyl-L-homocysteine


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Caenorhabditis elegans)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Mus musculus)


name: NAD(+) + S-(hydroxymethyl)glutathione => H(+) + NADH + S-formylglutathione


name: (2R,5R)-isomenthone + NADP(+) = (R)-pulegone + H(+) + NADPH


name: Furin cleaves pro-factor X to factor X (Homo sapiens)


name: PKA/PKG phosphorylate Rap1GAP2 (Gallus gallus)


name: a ganglioside GM3 (d18:1(4E)) + H2O => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + N-acetylneuraminate


name: 2-hydroxy-3-oxopropanoate + pyruvate => 5-dehydro-4-deoxy-D-glucarate


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Canis familiaris)


name: (3R)-3-[(carboxymethyl)amino]butanoate + 2 2-oxoglutarate + 2 O2 <=> (3R)-3-isocyanylbutanoate + 3 CO2 + 2 H2O + 2 succinate


name: H2O + N,1-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(9Z-octadecenoyl) ethanolamine


name: p-S742 TBX3 binds ID1 promoter (Homo sapiens)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Bos taurus)


name: H2O + hexadecanoate ester => an aliphatic alcohol + H(+) + hexadecanoate


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine <=> 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA


name: a fatty acid + ethanol + H(+) => a fatty acid ethyl ester + H2O


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Canis familiaris)


name: Phosphorylation of CRMPs by Cdk5 (Mus musculus)


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Schizosaccharomyces pombe)


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Homo sapiens)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Canis familiaris)


name: 1-(ergostan-3beta-yl)-L-aspartate + H2O = ergosterol + H(+) + L-aspartate


name: a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + diphosphate + H(+) => a 5'-end NTP-ribonucleotide-RNA + H2O


name: SUMOylation of NPM1 with SUMO2,3 (Mus musculus)


name: 1-O-hexadecyl-2-acetyl-3-hexadecanoyl-sn-glycerol + CoA => 1-O-hexadecyl-2-acetyl-sn-glycerol + hexadecanoyl-CoA


name: Mitochondrial H2O2 decarboxylates PYR to acetate (Homo sapiens)


name: H2O + P(1),P(4)-bis(5'-guanosyl) tetraphosphate = GMP + GTP + 2 H(+)


name: MAP2K2 phosphorylates MAPK1 (Danio rerio)


name: L-aspartyl-[protein] + NAD(+) <=> 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide


name: Formation of the inner ring of the 20S thymoproteasome core particle (Drosophila melanogaster)


name: PXLP-K212-CTH cleaves L-Cystathionine (Dictyostelium discoideum)


name: chloride(out) + D-methionine(out) + 2 Na(+)(out) => chloride(in) + D-methionine(in) + 2 Na(+)(in)


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Rattus norvegicus)


name: Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Rattus norvegicus)


name: luteolin + S-adenosyl-L-methionine <=> diosmetin + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Sus scrofa)


name: Caspase 8 or 10 recruitment to IPS1 complex followed by their dimerization (Gallus gallus)


name: (2E,6E)-omega-hydroxy-farnesol + H2O + NADP(+) => (2E,6E)-farnesol + H(+) + NADPH + O2


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Gallus gallus)


name: 8-demethyl-8-(methylamino)riboflavin + S-adenosyl-L-methionine => H(+) + roseoflavin + S-adenosyl-L-homocysteine


name: H2O + O-phospho-L-serine => L-serine + phosphate


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Gallus gallus)


name: ATP + H2O + leukotriene C4(out) => ADP + H(+) + leukotriene C4(in) + phosphate


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Drosophila melanogaster)


name: Arachidonate is epoxidated to 5,6-EET by CYP(4) (Homo sapiens)


name: 3-dehydro-6-deoxoteasterone + O2 + reduced [NADPH--hemoprotein reductase] = 3-dehydro-6alpha-hydroxyteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: [eIF5A protein]-deoxyhypusine + propane-1,3-diamine => [eIF5A protein]-L-lysine + spermidine


name: (4R)-hydroxysphinganine(in) + ATP + H2O => (4R)-hydroxysphinganine(out) + ADP + H(+) + phosphate


name: 2'-deoxymugineate + NAD(+) = 3''-deamino-3''-oxonicotianamine + H(+) + NADH


name: C5b:C6:C7 translocates to the plasma membrane (Sus scrofa)


name: ESTG binds ESR2:chaperone complex (Gallus gallus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Rattus norvegicus)


name: CXXC4 binds DVL to prevent AXIN binding (Homo sapiens)


name: NADP(+) + trypanothione => H(+) + NADPH + trypanothione disulfide


name: asnovolin I + S-adenosyl-L-methionine = asnovolin K + S-adenosyl-L-homocysteine


name: Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Canis familiaris)


name: 3-hydroxyisoheptadecanoyl-CoA + NADP(+) = 3-oxoisoheptadecanoyl-CoA + H(+) + NADPH


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Canis familiaris)


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Bos taurus)


name: Dissociation of CaM and CAMK2 autophosphorylation (Caenorhabditis elegans)


name: 2-hydroxycyclohexan-1-one + H(+) + NADPH + O2 = 6-hydroxyhexan-6-olide + H2O + NADP(+)


name: KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Homo sapiens)


name: Butyrate Response Factor1 (BRF1) binds AU-rich element in 3' UTR of mRNA (Gallus gallus)


name: USP18 binds IKBKG within IKK complex (Sus scrofa)


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Drosophila melanogaster)


name: 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+) => 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol + ATP


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Danio rerio)


name: Discoidal HDL binds membrane-associated free cholesterol (Bos taurus)


name: 2,4-dihydroxy-3-methyl-6-(2-oxoundecyl)benzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP] + S-adenosyl-L-homocysteine => AH2 + decanoyl-[ACP] + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine


name: (8Z,11Z,14Z)-eicosatrienoate + O2 <=> (15S)-hydroperoxy-(8Z,11Z,13E)-eicosatrienoate


name: Pannexin-1 (PANX1) channel transports ATP from the cytosol to the extracellular region (Homo sapiens)


name: SPHK1 phosphorylates sphingoid (Dictyostelium discoideum)


name: L-glutamine transmembrane transporter activity


name: (R)-1-phenylethylamine + H2O + NAD(+) = acetophenone + H(+) + NADH + NH4(+)


name: 2 ATP + H2O + hydrogencarbonate + L-glutamine <=> 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + dodecanoyl-CoA <=> 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: C3d-complexed antigen binds to complement receptor (Canis familiaris)


name: UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG (Mus musculus)


name: IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Canis familiaris)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Gallus gallus)


name: SREBP1A,1C,2 binds Importin beta-1 (Mus musculus)


name: Cleavage of mRNA at the 3'-end (Homo sapiens)


name: dihydrosanguinarine + NADP(+) => NADPH + sanguinarine


name: p-4Y-SIRPA:CD47 binds SKAP2 (Canis familiaris)


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Danio rerio)


name: LMF1,2 bind LIPC dimer (Rattus norvegicus)


name: eicosanoyl-CoA + FAD + H(+) => (2E)-eicosenoyl-CoA + FADH2


name: (9Z)-hexadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (9Z,12Z)-hexadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SEC31:SEC13 and v-SNARE recruitment (Mus musculus)


name: GTP loading by Rheb (Caenorhabditis elegans)


name: prostaglandin E2(out) <=> prostaglandin E2(in)


name: COX18 inserts nascent MT-CO2 in COX20:TMEM77 (Mus musculus)


name: MLCL is acylated to CL by LCLAT1 (ER) (Xenopus tropicalis)


name: PTPN3 binds p-T183,Y185 MAPK12 (Rattus norvegicus)


name: SGSH hydrolyses Heparan sulfate chain(2) (Sus scrofa)


name: ADH5 oxidises S-HMGSH to S-FGSH (Rattus norvegicus)


name: ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Canis familiaris)


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: 5-hydroxyisourate + H2O + NADP(+) => H(+) + NADPH + O2 + urate


name: (2E,6E)-farnesyl diphosphate = (2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate


name: 7-hydroxy-8-methoxycoumarin + H(+) + S-adenosyl-L-homocysteine => 7,8-dihydroxycoumarin + S-adenosyl-L-methionine


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Danio rerio)


name: Interaction of PECAM-1 and SHP-2 (Bos taurus)


name: all-trans-retinol--[retinol-binding protein] + NAD(+) = all-trans-retinal--[retinol-binding protein] + H(+) + NADH


name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 (Mus musculus)


name: WIPI2 binds ATG12:ATG5:ATG16L (Gallus gallus)


name: 9-hydroxy-octadecanoate + H(+) + hexadecanoate => 9-hexadecanoyloxy-octadecanoate + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1-(10Z-heptadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: Sequestration of BAD protein by 14-3-3 (Sus scrofa)


name: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnose + H2O = 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Danio rerio)


name: Formation of Elongin complex (Rattus norvegicus)


name: RHOQ GEFs activate RHOQ (Schizosaccharomyces pombe)


name: 2,5-dioxopiperazine + H2O = glycylglycine


name: MDM2 gene expression is repressed by NPAS4 (Homo sapiens)


name: Activated FGFR1 phosphorylates FRS3 (Canis familiaris)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Homo sapiens)


name: atROL binds RBP1 (parenchymal cell) (Danio rerio)


name: HSD11B1 hydrogenates PREDN to PREDL in hepatic cell (Xenopus tropicalis)


name: (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Bos taurus)


name: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O => alpha-D-ribose 1,5-bisphosphate + H(+)


name: Association of Golgi  transport vesicles with microtubules (Mus musculus)


name: RGGT:CHM binds RABs (Drosophila melanogaster)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 = 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O


name: GLUT7 and GLUT11 transport glucose and fructose (Saccharomyces cerevisiae)


name: (6R,7S)-2,2,6-trimethyl-10-methylenebicyclo[5.4.0]undec-1(11)-ene + diphosphate => (2Z,6E)-farnesyl diphosphate


name: DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Caenorhabditis elegans)


name: GPRIN1 gene expression is stimulated by MECP2 (Homo sapiens)


name: RAR:RXR binds SUMO-CRABP2:atRA (Canis familiaris)


name: 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine


name: LHPP:Mg2+ dimer hydrolyses PPi (Canis familiaris)


name: arginine + H2O => ornithine + urea [ARG1] (Caenorhabditis elegans)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)


name: a ganglioside GD3 (d18:1(4E)) + H2O => a ganglioside GM3 (d18:1(4E)) + N-acetylneuraminate


name: (6S)-5,6,7,8-tetrahydrofolate + O2 + sarcosine <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O2


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Bos taurus)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Bos taurus)


name: Binding of IRS to insulin receptor (Sus scrofa)


name: GSDMD (1-275) binds bacterial cardiolipin (Mus musculus)


name: hexan-2-one + hydrogen cyanide = (2S)-2-hydroxy-2-methylhexanenitrile


name: formate(out) + 2 H(+)(in) + ubiquinone-8 = CO2(out) + H(+)(out) + ubiquinol-8


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Bos taurus)


name: Bradykinin receptors B1 and B2 bind to bradykinin (Canis familiaris)


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate <=> (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: 2 (S)-methylmalonyl-CoA + 10 H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 3 malonyl-CoA + 5 NADPH <=> C32-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)


name: an N-acylsphing-4-enine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: butanoate(out) + estrone 3-sulfate(in) <=> butanoate(in) + estrone 3-sulfate(out)


name: NMRK2 phosphorylates NAR to yield NAMN (Dictyostelium discoideum)


name: PC is exchanged with PI by PITPNB (Rattus norvegicus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Danio rerio)


name: a 1-acyl-sn-glycerol + H(+) + phosphocholine => a 1-acyl-sn-glycero-3-phosphocholine + H2O


name: NGEF exchanges GTP for GDP on RHOA (Bos taurus)


name: 7-O-geranyl-2-O,3-dimethylflaviolin + diphosphate => (2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin + H(+)


name: 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+) => 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + CO2


name: (25R)-3beta-hydroxy-5-cholesten-26-al + H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta-hydroxy-5-cholestenoate + H2O + 2 oxidized [adrenodoxin]


name: ULK1 phosphorylates Beclin-1 (Schizosaccharomyces pombe)


name: fumarate + L-cysteinyl-[protein] <=> S-(2-succinyl)-L-cysteinyl-[protein]


name: NAD(+) + trans-4-hydroxycyclohexane-1-carboxylate = 4-oxocyclohexane-1-carboxylate + H(+) + NADH


name: TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains  (Homo sapiens)


name: MRN complex bound to shortened telomeres recruits ATM (Bos taurus)


name: dehydrodolichyl diphosphate synthase activity


name: LDHAL6B reduces PYR to LACT (Mus musculus)


name: 2-acyl LPE is acylated to PE by LPEAT (Plasmodium falciparum)


name: 3 S-adenosyl-L-methionine <=> 3 H(+) + nicotianamine + 3 S-methyl-5'-thioadenosine


name: D-arabino-hex-3-ulose 6-phosphate <=> beta-D-fructose 6-phosphate


name: Translocation of CARMA1 to Plasma membrane (Rattus norvegicus)


name: SFTPB dimer,C translocate from multivesicle body to lamellar body (Mus musculus)


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 1-O-methyl-12-hydroperoxy-20-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: aclacinomycin A + O2 = aclacinomycin Y + H2O2


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)


name: (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein] => (5Z)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: 4-methylsulfanyl-2-oxobutanoate + H(+) + NADPH => (2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NADP(+)


name: AcK-NFE2L2 binds the NFE2L2 gene (Homo sapiens)


name: ATP7A transports cytosolic Cu2+ to extracellular region (Rattus norvegicus)


name: THRSP gene expression is stimulated by PPARG2:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Homo sapiens)


name: 5-methylsulfanyl-2,3-dioxopentyl phosphate <=> 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Gallus gallus)


name: Phosphorylation of PIP2 to PIP3 by PI3K (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ATP + CoA = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + AMP + diphosphate


name: CECRI deaminates Ade-Rib to Ino (Sus scrofa)


name: chylomicron remnant:apoE:LDLR complex [plasma membrane] => chylomicron remnant:apoE:LDLR complex [clathrin-coated vesicle] (LDLRAP1-dependent) (Canis familiaris)


name: BOD1L1 binds SET1A complex (Rattus norvegicus)


name: NAD(+) + UDP-2-acetamido-2,6-dideoxy-beta-L-talose => H(+) + NADH + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose


name: MAP3K5 phosphorylates MKK3 and MKK6 (Drosophila melanogaster)


name: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin


name: GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 (Bos taurus)


name: SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Gallus gallus)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Canis familiaris)


name: A + H2O + quinolin-6-ol = 6-hydroxyquinolin-2(1H)-one + AH2


name: ADP + thiamine diphosphate <=> AMP + thiamine triphosphate


name: GGPS1 hexamer transfers IPPP to DMAPP (Saccharomyces cerevisiae)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Bos taurus)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Bos taurus)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: NT5C2 tetramer phosphorylates RBV (Canis familiaris)


name: NSF and SNAPs bind cis-SNARE complex (Homo sapiens)


name: HRH1 binds hist (Caenorhabditis elegans)


name: 2 H(+)(out) + L-alanyl-L-alanine(out) => 2 H(+)(in) + L-alanyl-L-alanine(in)


name: 5-guanidino-2-oxopentanoate + S-adenosyl-L-methionine = (3R)-5-guanidino-3-methyl-2-oxopentanoate + H(+) + S-adenosyl-L-homocysteine


name: 2-demethylmenaquinone-8 + dimethyl sulfide + H2O => 2-demethylmenaquinol-8 + dimethyl sulfoxide


name: bilirubin IXalpha bis-beta-D-glucuronoside(out) = bilirubin IXalpha bis-beta-D-glucuronoside(in)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Mus musculus)


name: SORD tetramer oxidizes xylitol to D-xylulose (Xenopus tropicalis)


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O => 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H(+) + phosphocholine


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Canis familiaris)


name: dehydroepiandrosterone 3-sulfate(in) + pentanoate(out) <=> dehydroepiandrosterone 3-sulfate(out) + pentanoate(in)


name: AICAR + 10-Formyl-THF => FAICAR + THF (Sus scrofa)


name: 1-hydroxy-6-methoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-methionine = 1,6-dimethoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-homocysteine


name: PKM dephosphorylates PEP to PYR (Homo sapiens)


name: epsilon-(gamma-L-glutamyl)-L-lysine = 5-oxo-L-proline + L-lysine


name: (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH => (1R,2S)-ephedrine + NAD(+)


name: 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphoethanolamine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine => 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexanoyl-sn-glycero-3-phosphoethanolamine


name: 3-phenylpropylamine + pyruvate = 3-phenylpropanal + L-alanine


name: TGFBR3 binding to FGF2 (Rattus norvegicus)


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Schizosaccharomyces pombe)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Rattus norvegicus)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:GRB2:SOS1) (Xenopus tropicalis)


name: OMA1 hydrolyzes YME1L1 (Rattus norvegicus)


name: Addition of GlcNAc to the glycan on the A arm (Caenorhabditis elegans)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Sus scrofa)


name: OCT1 transports organic cations out of hepatic cells (Sus scrofa)


name: cholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (22R)-hydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: Thrombin-activated PARs:Gq (active) dissociate (Canis familiaris)


name: 4-coumaroyl-CoA + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside = a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] + CoA


name: all-trans-5,6-epoxyretinoyl-1-O-(beta-D-glucuronate) + UDP => all-trans-5,6-epoxyretinoate + UDP-alpha-D-glucuronate


name: Coumarin is 7-hydroxylated by CYP2A13 (Rattus norvegicus)


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Canis familiaris)


name: a globoside Gb3Cer (d18:1(4E)) + H2O = a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + D-galactose


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Gallus gallus)


name: Loading of antigen peptide onto MHC class I molecule (Gallus gallus)


name: Formation of lysyl-pyridinoline cross-links (Sus scrofa)


name: CTP(in) + dUTP(out) => CTP(out) + dUTP(in)


name: H(+) + N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine => L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine


name: 3-oxochol-4-en-22-oyl-CoA + NAD(+) <=> 3-oxochola-1,4-dien-22-oyl-CoA + H(+) + NADH


name: 5-guanidino-2-oxopentanoate + S-adenosyl-L-methionine => (3R)-5-guanidino-3-methyl-2-oxopentanoate + H(+) + S-adenosyl-L-homocysteine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p75NTR and RHOA-GDI interact (Mus musculus)


name: 16alpha,17alpha-dihydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] => 6beta,16alpha,17alpha-trihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTGS2 dimer oxidises DHA to 13-HDHA (Xenopus tropicalis)


name: oxoglutarate dehydrogenase [NAD(P)+] activity


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Gallus gallus)


name: an N-acyl-L-homoserine lactone + H2O = a carboxylate + L-homoserine lactone


name: adenosine 3',5'-bisphosphate(out) + FAD(in) = adenosine 3',5'-bisphosphate(in) + FAD(out)


name: NEIL1 translocates to the nucleus (Canis familiaris)


name: Binding of the MCC complex to the APC/C complex (Mus musculus)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Sus scrofa)


name: Polyubiquitination of substrate (Danio rerio)


name: 5,12-dihydroxanthommatin + NAD(+) => H(+) + NADH + xanthommatin


name: Collagen type XXV ectomain shedding (Rattus norvegicus)


name: (24S)-hydroxycholesterol + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine = (24S)-hydroxycholesterol 3-linoleoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: BRD7 promotes EP300-mediated acetylation of TP53 (Canis familiaris)


name: Arachidonate is oxidised to 5S-HpETE by ALOX5 (Homo sapiens)


name: 3-oxalomalate => glyoxylate + oxaloacetate


name: ALD3A1 oxidises 4HPCP to CXPA (Sus scrofa)


name: PRC1 SUMOylates CASP8AP2 with SUMO1 (Homo sapiens)


name: (10S)-hydroxy-(12Z)-octadecenoate + NAD(+) <=> 10-oxo-(12Z)-octadecenoate + H(+) + NADH


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Canis familiaris)


name: H(+) + phlorizin + UDP => phloretin + UDP-alpha-D-glucose


name: BRF1 Complex recruits RNA degradation activities (Mus musculus)


name: 1,2,3-trioctanoylglycerol + H2O <=> dioctanoylglycerol + H(+) + octanoate


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Rattus norvegicus)


name: MTMR6 binds MTMR9 (Drosophila melanogaster)


name: SARS-CoV-2 3a tetramer binds to VPS39 within HOPS complex (Homo sapiens)


name: KRAS4B is phosphorylated on serine 181 (Canis familiaris)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O = an N-acyl-sphingoid base + lactose


name: an N-hexadecanoyl-sphingoid base + CoA + H(+) => a sphingoid base + hexadecanoyl-CoA


name: furfural + hydrogen cyanide = (2R)-2-(furan-2-yl)-2-hydroxyacetonitrile


name: 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + CTP = CMP-beta-3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + diphosphate


name: an N-acylsphing-4-enine + CDP-choline => a sphingomyelin + CMP + H(+)


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Rattus norvegicus)


name: a ganglioside GA1 (d18:1(4E)) + H(+) + UDP => a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose


name: SeMet is converted to AdoSeMet by MAT (Canis familiaris)


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Mus musculus)


name: CO2 + H2O + pentadecanoate => (R)-2-hydroxyhexadecanoate + O2


name: 5-amino-6-(D-ribitylamino)uracil + glyoxal = 5-(2-oxoethylideneamino)-6-(D-ribitylamino)uracil + H2O


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Rattus norvegicus)


name: ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA (Homo sapiens)


name: ATG7:ATG3:LC3 dissociates (Drosophila melanogaster)


name: cathasterone + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + teasterone


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Gallus gallus)


name: maleate(in) + sulfate(out) = maleate(out) + sulfate(in)


name: a 1,2-diacyl-sn-glycerol(in) = a 1,2-diacyl-sn-glycerol(out)


name: Type X collagen associates with collagen type II fibrils (Bos taurus)


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Bos taurus)


name: p-Y397-PTK2 binds SRC (Caenorhabditis elegans)


name: L-isoleucine(in) + L-phenylalanine(out) <=> L-isoleucine(out) + L-phenylalanine(in)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Caenorhabditis elegans)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Gallus gallus)


name: D-xylulose 5-phosphate + formaldehyde <=> D-glyceraldehyde 3-phosphate + dihydroxyacetone


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Rattus norvegicus)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Gallus gallus)


name: NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: L-cysteinyl-[NO transferase protein] + N(omega)-hydroxy-L-arginine + O2 <=> H(+) + H2O + L-citrulline + S-nitroso-L-cysteinyl-[NO transferase protein]


name: PTPRZ dephosphorylates ligand-bound ALK dimers (Bos taurus)


name: ARBB recruits GPCRs into clathrin-coated pits (Canis familiaris)


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Danio rerio)


name: Cdc45 associates with the pre-replicative complex at the origin (Gallus gallus)


name: RAS guanyl nucleotide exchange by SOS1 associated with RANBP9 and MET (Rattus norvegicus)


name: 1,2-dinitroglycerol + NADPH = 2-nitroglycerol + NADP(+) + nitrite


name: USP9X (FAM) deubiquitinates SMAD4 (Mus musculus)


name: H2O + L-alanyl-L-cysteine = L-alanine + L-cysteine


name: 3-carboxy-2-oxobutanoate + H(+) => 2-oxobutanoate + CO2


name: RUNX2 and RB1 bind the COL1A1 gene promoter (Homo sapiens)


name: osmolarity-sensing monoatomic cation channel activity


name: [small archaeal modifier protein]-C-terminal Gly-Gly + ATP + H(+) = [small archaeal modifier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: (E)-3-(indol-3-yl)acryloyl-CoA + (R)-3-(indol-3-yl)lactate <=> (E)-3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA


name: CAD hexamer transforms L-Gln to CAP (Mus musculus)


name: Phosphorylated SHC1 recruits SHIP (Gallus gallus)


name: diphosphate + Mo-molybdopterin guanine dinucleotide => GTP + H(+) + Mo-molybdopterin


name: acetate + 2 H(+) + NADPH => acetaldehyde + H2O + NADP(+)


name: Association of procollagen type XIX (Rattus norvegicus)


name: SMURF1/2 ubiquitinates PRICKLE1 (Sus scrofa)


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Caenorhabditis elegans)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Rattus norvegicus)


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Caenorhabditis elegans)


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Sus scrofa)


name: Caspase-mediated cleavage of claspin (Homo sapiens)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Canis familiaris)


name: ATXN3 binds polyUb-PARK2 (Gallus gallus)


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Dictyostelium discoideum)


name: L-arginine(in) + L-histidine(out) <=> L-arginine(out) + L-histidine(in)


name: 3-hydroxy-2-methylpropanoyl-CoA + H2O => 3-hydroxy-2-methylpropanoate + CoA + H(+)


name: 3-hydroxypentacecilide A + H(+) + NADPH + O2 <=> chrodrimanin F + H2O + NADP(+)


name: calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration


name: Degradation multiubiquitinated Cyclin A (Bos taurus)


name: CFTR transports Cl- from cytosol to extracellular region (Gallus gallus)


name: STAT3 phosphorylation (Canis familiaris)


name: Galpha-olf:GTP binds to adenylate cyclase and activates it (Rattus norvegicus)


name: RHOD binds effectors at the Golgi membrane (Gallus gallus)


name: (3R)-3-hydroxydecanoyl-CoA + NADP(+) = 3-oxodecanoyl-CoA + H(+) + NADPH


name: SLC16A10-mediated uptake of aromatic amino acids (Rattus norvegicus)


name: 3beta-hydroxy-16alpha,17alpha-epoxypregnenolone + UDP-alpha-D-glucose = 3beta-hydroxy-16alpha,17alpha-epoxypregnenolone 3-beta-D-glucoside + H(+) + UDP


name: estrone 3-sulfate(out) => estrone 3-sulfate(in)


name: 4-deoxy-6-O-methyl-L-threo-hex-4-enopyranuronate + [(1->4)-alpha-D-galacturonosyl methyl ester](n-1) => [(1->4)-alpha-D-galacturonosyl methyl ester](n)


name: an N-acyl-D-mannosamine + ATP <=> ADP + an N-acyl-D-mannosamine 6-phosphate + H(+)


name: 4 H(+) + N(2)-dimethylguanosine(26)/N(2)-dimethylguanosine(27) in tRNA + 4 S-adenosyl-L-homocysteine => guanosine(26)/guanosine(27) in tRNA + 4 S-adenosyl-L-methionine


name: Ubiquitination of CD4 by Vpu:CD4:beta-TrCP:SKP1 complex (Homo sapiens)


name: low-affinity basic amino acid transmembrane transporter activity


name: a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP


name: RNF146 polyubiquitinates PARylated PTEN (Xenopus tropicalis)


name: 3''-dehydroorientin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: Pannexin 1/Pannexin2 mediated neuronal gap junction communication (Rattus norvegicus)


name: a 2-hydroxy carboxylate + O2 = a 2-oxocarboxylate + H2O2


name: glycine + 2 S-adenosyl-L-methionine = 2 H(+) + N,N-dimethylglycine + 2 S-adenosyl-L-homocysteine


name: (6Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: PI3-kinase binds to the active receptor (Danio rerio)


name: 4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine = 4-(3-methylbut-2-enyl)-L-abrine + H(+) + S-adenosyl-L-homocysteine


name: WNT5A binds FZD and ROR receptors (Canis familiaris)


name: 2-oxoglutarate + a 5-methyl-2'-deoxycytidine in DNA + O2 => a 5-hydroxymethyl-2'-deoxycytidine in DNA + CO2 + succinate


name: BAP1:Ub-HCFC1 deubiquitinates BAP1:Ub-HCFC1 (Homo sapiens)


name: PP2A dephosphorylates BANF1 (Mus musculus)


name: 4-nitrobenzaldehyde + H2O + NAD(+) = 4-nitrobenzoate + 2 H(+) + NADH


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Danio rerio)


name: (1S,2S,4R)-endo-fenchol + NADP(+) => (1S,4R)-fenchone + H(+) + NADPH


name: citrate(out) + trans-aconitate(in) => citrate(in) + trans-aconitate(out)


name: DUOX1,2 reduce O2 to H2O2 (Homo sapiens)


name: A4GALT transfers galactose to LacCer (Sus scrofa)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Mus musculus)


name: a very-long-chain (2E)-enoyl-CoA + H2O => a very-long-chain (3R)-3-hydroxyacyl-CoA


name: PGLYRP1 binds bacterial peptidoglycan (Mus musculus)


name: ST8SIA5 transfers Neu5Ac to gangliosides (Canis familiaris)


name: VEGFR2 autophosphorylates (Xenopus tropicalis)


name: an alcohol + D-glucuronate => a beta-D-glucuronoside + H2O


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Saccharomyces cerevisiae)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Xenopus tropicalis)


name: deamido-NAD(+) + hydrogencarbonate <=> AMP + 2 H(+) + pyridinium-3,5-dicarboxylate mononucleotide


name: ATP + H2O + thiamine(out) <=> ADP + H(+) + phosphate + thiamine(in)


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Canis familiaris)


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + 1D-myo-inositol 3-phosphate => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)


name: L-Glutamate binds GRM1 (mGluR1) (Homo sapiens)


name: ZIP6 and ZIP14 mediate zinc influx into cells (Homo sapiens)


name: ATP + L-citrulline + NH4(+) => ADP + H(+) + L-arginine + phosphate


name: Lactoperoxidase (LPO) produces OSCN- (Homo sapiens)


name: Cannabinoid receptors can bind cannabinoids (Canis familiaris)


name: ARBB recruits GPCRs into clathrin-coated pits (Sus scrofa)


name: WNT5A binding to FZD promotes PRICKLE1 degradation (Drosophila melanogaster)


name: HSF1 trimer translocates to the nucleus (Homo sapiens)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Homo sapiens)


name: 3-sulfinopropanoate + H(+) => 3-sulfanylpropanoate + O2


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Sus scrofa)


name: a long-chain fatty acid + 3 H(+) + 2 NADH => a long-chain primary fatty alcohol + H2O + 2 NAD(+)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA <=> 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: (R)-malate + NAD(+) = CO2 + NADH + pyruvate


name: catalytic activity, acting on a nucleic acid


name: E2F7 forms homodimers (Rattus norvegicus)


name: 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine


name: catechol + CO2 + NAD(+) + NH4(+) => anthranilate + 3 H(+) + NADH + O2


name: 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + dimethylallyl diphosphate => 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + diphosphate


name: [(1->4)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate => [(1->4)-beta-D-glucosyl](n) + phosphate


name: (2E,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H2O => (3R)-hydroxy-(21Z,24Z,27Z,30Z,33Z)-hexatriacontapentaenoyl-CoA


name: H(+) + NADPH + tetradecanal => NADP(+) + tetradecan-1-ol


name: 2xPDKX:2xZn2+ phosphorylates PDX (Schizosaccharomyces pombe)


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Homo sapiens)


name: Conversion of malonyl-CoA and acetyl-CoA to palmitate (Caenorhabditis elegans)


name: Binding of TFIIIC to TFIIIA:Type I Promoter complex  (Dictyostelium discoideum)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)


name: 2-deoxy-alpha-D-ribose 1-phosphate + uracil => 2'-deoxyuridine + phosphate


name: (2E)-geranyl diphosphate + H2O = (1S,2S,4R)-endo-fenchol + diphosphate


name: Multiubiquitination of Nek2A (Gallus gallus)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Caenorhabditis elegans)


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)


name: a ganglioside Ac-O-9-GD3(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside Ac-O-9-GD2(d18:1(4E)) + H(+) + UDP


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Homo sapiens)


name: ADP + alpha-maltose 1-phosphate + H(+) => ATP + D-maltose


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Bos taurus)


name: 2-oxoglutarate + H(+) + NADH + NH4(+) => D-glutamate + H2O + NAD(+)


name: A + a (4R,8E)-4-hydroxysphingenine ceramide + 2 H2O => AH2 + an N-acyl-(4R)-4-hydroxysphinganine + O2


name: GRIN2B gene expression is inhibited by MECP2 (Homo sapiens)


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Danio rerio)


name: NFE2L2 translocates from cytosol to nucleoplasm (Caenorhabditis elegans)


name: RAC1,RAC2,RHOG activate PI3K (Mus musculus)


name: (2E)-tetracosenoyl-CoA + reduced [electron-transfer flavoprotein] => H(+) + oxidized [electron-transfer flavoprotein] + tetracosanoyl-CoA


name: NAD(+) + propanoyl-CoA = acryloyl-CoA + H(+) + NADH


name: (2S)-3-sulfolactaldehyde + D-sedoheptulose 7-phosphate => 6-deoxy-6-sulfo-D-fructose + D-erythrose 4-phosphate


name: CDC42:GTP recruits DIAPH2-2 to kinetochores (Mus musculus)


name: 2-methoxy-6-(all-trans-nonaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine => 3-(all-trans-nonaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine


name: Interaction of integrin alphaIIbbeta3 with Fibronectin (Rattus norvegicus)


name: nuatigenin + UDP-alpha-D-glucose <=> H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP


name: C4b binding protein binds Protein S (Homo sapiens)


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Mus musculus)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Mus musculus)


name: p-Y407-YAP1 translocates from the cytosol to the nucleoplasm (Sus scrofa)


name: ethanol + 2 Fe(III)-[cytochrome c] => acetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 = 2-glyceryl-prostaglandin G2


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Gallus gallus)


name: H(+) + rifamycin SV + S-adenosyl-L-homocysteine => 27-O-demethylrifamycin SV + S-adenosyl-L-methionine


name: CLK is degraded by the 26S proteasome (Drosophila melanogaster)


name: Sustained activation of SRC kinase by SHP2 (Mus musculus)


name: TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers and YY1 stimulate ERBB2 gene expression (Homo sapiens)


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Xenopus tropicalis)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Sus scrofa)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: RHOD translocates to the Golgi membrane (Schizosaccharomyces pombe)


name: RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 (Mus musculus)


name: H(+) + palmatine + S-adenosyl-L-homocysteine => columbamine + S-adenosyl-L-methionine


name: L-histidine + S-adenosyl-L-methionine <=> (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: SDHAF4 binds to FAD-SDHA (Saccharomyces cerevisiae)


name: brevianamide F + dimethylallyl diphosphate = diphosphate + tryprostatin B


name: (2E)-geranyl diphosphate = (E)-beta-ocimene + diphosphate


name: [(1->2)-beta-D-glucosyl](n) + phosphate => [(1->2)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: HMOX1 translocates from the cytosol to the nucleoplasm (Canis familiaris)


name: RNF43 frameshift mutants show enhanced WNT siganling (Homo sapiens)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Rattus norvegicus)


name: 3 A + 10 CO2 + 11 CoA + cordypyrone A + 8 H2O + 8 NADP(+) => acetyl-CoA + 3 AH2 + 18 H(+) + 10 malonyl-CoA + 8 NADPH


name: 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Homo sapiens)


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Caenorhabditis elegans)


name: ATAT acetylates microtubules (Plasmodium falciparum)


name: H(+) + menaquinol-8 + trimethylamine N-oxide = H2O + menaquinone-8 + trimethylamine


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Mus musculus)


name: NEK9 phosphorylates NEK6/NEK7 (Homo sapiens)


name: (2S)-2-hydroxy-2-methylhexanenitrile => hexan-2-one + hydrogen cyanide


name: OTUD3 deubiquitinates PTEN (Caenorhabditis elegans)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Drosophila melanogaster)


name: 2-oxobutanoate + L-kynurenine => (2S)-2-aminobutanoate + H2O + kynurenate


name: Furin cleaves pro-factor X to factor X (Mus musculus)


name: 4-methylumbelliferone + phenyl sulfate => 4-methylumbelliferone sulfate + phenol


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + AH2 + S-adenosyl-L-methionine => 5'-deoxyadenosine + 5-hydroxybenzimidazole + A + formate + 2 H(+) + L-methionine + NH4(+) + phosphate


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Canis familiaris)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[12] (Saccharomyces cerevisiae)


name: ATP + H2O + sulfate(out) = ADP + H(+) + phosphate + sulfate(in)


name: a ganglioside Fuc-GM1 + H2O = alpha-Fuc-(1->2)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-Glc + an N-acyl-sphingoid base


name: 7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + 2 H(+) + L-methionine


name: Keratin type I/type II heterodimers form tetramers (Canis familiaris)


name: Formation of MSH1:PMS2 Complex (Plasmodium falciparum)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: betaine aldehyde + H2O + O2 = glycine betaine + H(+) + H2O2


name: Activated FGFR1 phosphorylates FRS2 (Rattus norvegicus)


name: beta-D-GalNAc-(1->4)-alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + H2O => alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + N-acetyl-D-galactosamine


name: Adenylate cyclase converts ATP into cyclic AMP (Danio rerio)


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-(9Z,12Z-octadecadienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: NADP(+) + propanal <=> acrolein + H(+) + NADPH


name: Monoubiquitinated PTEN translocates to the nucleus (Bos taurus)


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Rattus norvegicus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate => dimethylallyl diphosphate + 4 isopentenyl diphosphate


name: 2-oxoglutarate + pyridoxamine 5'-phosphate <=> D-glutamate + pyridoxal 5'-phosphate


name: Active ALK phosphorylates JAK3 (Canis familiaris)


name: 5-N(alpha)-putrescinyl-dTMP in DNA + phosphate => 5-phosphomethyl-dUMP in DNA + putrescine


name: PIAS2,3,4 SUMOylate RORA with SUMO2 (Rattus norvegicus)


name: Defective GBE1 does not catalyze branch formation in growing glycogen chains (liver) (Homo sapiens)


name: 5,6-dihydrouridine(16) in tRNA + NADP(+) => H(+) + NADPH + uridine(16) in tRNA


name: acetyl-CoA + tetradecanoyl-CoA = 3-oxohexadecanoyl-CoA + CoA


name: CoA + H(+) + N(1)-acetylspermidine => acetyl-CoA + spermidine


name: 6-decylubiquinol + tetrathionate => 6-decylubiquinone + 2 thiosulfate


name: L-iditol + NAD(+) <=> H(+) + keto-L-sorbose + NADH


name: aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate


name: DELE1(143-515) is released into the cytosol (Homo sapiens)


name: Endocytosis of protein 3a (Homo sapiens)


name: cirsiliol + S-adenosyl-L-methionine <=> eupatorin + H(+) + S-adenosyl-L-homocysteine


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Dictyostelium discoideum)


name: MATEs mediate extrusion of xenobiotics (Rattus norvegicus)


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Bos taurus)


name: NA activation of TGF-beta (Homo sapiens)


name: 2,4,6-trichlorophenol + FADH2 + O2 <=> 2,6-dichlorobenzoquinone + chloride + FAD + H(+) + H2O


name: Phospho-AKT1 phosphorylates NOS3 (eNOS) on serine-1177 (Dictyostelium discoideum)


name: ADP + phosphate + propanoyl-CoA => ATP + CoA + propanoate


name: 17alpha-ethynylestradiol + 3'-phosphoadenylyl sulfate = 17alpha-ethynylestradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 2 a 1-acylglycerol = a 1,2-diacylglycerol + glycerol


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)


name: a 3'-end ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end ribonucleotide-RNA + a ribonucleoside 5'-phosphate + H(+)


name: α1-agonists bind ADRA1A,B,D (Bos taurus)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Xenopus tropicalis)


name: L-glutaminyl-[protein] + S-adenosyl-L-methionine => H(+) + N(5)-methyl-L-glutaminyl-[protein] + S-adenosyl-L-homocysteine


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Drosophila melanogaster)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Danio rerio)


name: ATP + holo-[peptidyl-carrier protein] + L-threonine <=> AMP + diphosphate + L-threonyl-[peptidyl-carrier protein]


name: HOXB1 activates HOXB2 expression (Homo sapiens)


name: Basigin binds Mannose-carrying cell recognition molecules (Rattus norvegicus)


name: MLH1 variants-defective DNA mismatch repair (Homo sapiens)


name: dehydrogriseofulvin + H(+) + NADPH = griseofulvin + NADP(+)


name: JMJD6 demethylates MeR4-HIST1H4 (Drosophila melanogaster)


name: ent-7alpha-hydroxykaur-16-en-19-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => ent-kaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase]


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Danio rerio)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Drosophila melanogaster)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Rattus norvegicus)


name: very long-chain fatty acyl-CoA hydrolase activity


name: a very long-chain fatty acyl-CoA + H2O = a very long-chain fatty acid + CoA + H(+)


name: Auto-ubiquitination of TRAF3 (Mus musculus)


name: 2-methylbutanamine + H2O + NAD(+) <=> 2-methylbutanal + H(+) + NADH + NH4(+)


name: p-STAT1,p-STAT3 dissociate from IL24:IL20RA:p-Y1022,Y1023-JAK1:IL20RB:p-STAT1, p-STAT3 (Danio rerio)


name: ABC7, mABC1 and mABC2 mediate heme transport (Saccharomyces cerevisiae)


name: D-fructopyranose(in) + Na(+)(in) => D-fructopyranose(out) + Na(+)(out)


name: PTK6 translocates to the nucleus (Caenorhabditis elegans)


name: WNTs are secreted in exosomes (Canis familiaris)


name: H(+) + N-carbamoyl-D-methionine => D-5-[2-(methylsulfanyl)ethyl]hydantoin + H2O


name: "cyclic alcohol dehydrogenase (quinone)"


name: RHOF binds effectors at the plasma membrane (Mus musculus)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + H(+) + phosphate


name: malonate(in) + succinate(out) => malonate(out) + succinate(in)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)


name: ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 (Mus musculus)


name: D-xylose + NAD(+) <=> D-xylono-1,5-lactone + H(+) + NADH


name: all-trans-violaxanthin + L-ascorbate => all-trans-antheraxanthin + H2O + L-dehydroascorbate


name: DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Gallus gallus)


name: 5-HT2 receptor can bind serotonin (Drosophila melanogaster)


name: ATP + cholate(in) + H2O = ADP + cholate(out) + H(+) + phosphate


name: geranylgeranyl diphosphate <=> diphosphate + fusicocca-2,10(14)-diene


name: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = 5alpha-cholestane-3beta,5,6beta-triol


name: factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Homo sapiens)


name: PON1,3 hydrolyse ATVL to ATV (Canis familiaris)


name: PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Rattus norvegicus)


name: EPCAM binds itself to form homotypic cell adhesion (Mus musculus)


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Mus musculus)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Sus scrofa)


name: (9Z,12Z)-octadecadienoate + O2 <=> (13R)-hydroperoxy-(9Z,11E)-octadecadienoate


name: a sphingomyelin(out) + ADP + H(+) + phosphate => a sphingomyelin(in) + ATP + H2O


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Canis familiaris)


name: a 2-acyl-sn-glycero-3-phospho-L-serine + H2O => a 2-acyl-sn-glycerol 3-phosphate + H(+) + L-serine


name: 12-octadecanoyloxy-octadecanoate + H2O => 12-hydroxyoctadecanoate + H(+) + octadecanoate


name: a quinone + L-proline <=> (S)-1-pyrroline-5-carboxylate + a quinol + H(+)


name: PARVB/Affixin interacts with alpha PIX (Mus musculus)


name: CD22 binds itself to form homo-oligomers (Bos taurus)


name: IMPDH tetramers binds IMPDH inhibitors (Dictyostelium discoideum)


name: 9-O-10-oxo-(12Z)-octadecenoate L-aspartatyl ester-[protein] => 9S,10-epoxy-(10,12Z)-octadecadienoate + H(+) + L-aspartyl-[protein]


name: Bcl-2 and Bcl-XL bind NLRP1 (Homo sapiens)


name: Activated ATM phosphorylates DCLRE1C (Canis familiaris)


name: Caspase-mediated cleavage of occludin (Bos taurus)


name: Activation of GRIK3 homomer (Bos taurus)


name: (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-tyrosine


name: 4-formylbenzenesulfonate + H2O + NAD(+) => 4-sulfobenzoate + 2 H(+) + NADH


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Mus musculus)


name: 2-hydroxy-3-methylhexadecanoyl-CoA <=> 2-methylpentadecanal + formyl-CoA


name: Pol II elongation complex moves on the template as transcript elongates (Xenopus tropicalis)


name: USP44 deubiquitinates CDC20 (Xenopus tropicalis)


name: (2S)-2-hydroxy-2-methyl-3,3-dimethylbutanenitrile => 3,3-dimethylbutan-2-one + hydrogen cyanide


name: FAHD1 dimer hydrolyses OA to PYR (Canis familiaris)


name: PS is hydrolyzed to 1-acyl LPS by PLA2[15] (Xenopus tropicalis)


name: 2 AH2 + all-trans-zeaxanthin + 2 O2 = 2 A + all-trans-adonixanthin + 3 H2O


name: (S)-2-methyl-3-oxopropanoate + H2O + NAD(+) = 2 H(+) + methylmalonate + NADH


name: Fusion and Release of SARS-CoV-1 Nucleocapsid (Homo sapiens)


name: GPIb-IX-V binds to vWF:Collagen complex (Mus musculus)


name: UGCG transfers glucose to ceramide (Caenorhabditis elegans)


name: hydrogencarbonate + phosphoenolpyruvate => oxaloacetate + phosphate


name: cyclohexane-1-carbonyl-CoA + succinate => cyclohexane-1-carboxylate + succinyl-CoA


name: CoA + H(+) + N-acetylcadaverine => acetyl-CoA + cadaverine


name: PGR binds PGR antagonists (Homo sapiens)


name: (S)-4-hydroxymandelonitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-hydroxyphenylacetonitrile + O2 + reduced [NADPH--hemoprotein reductase]


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Caenorhabditis elegans)


name: GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate (Mus musculus)


name: N-hydroxy-L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N,N-dihydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]


name: (R)-axinyssene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: a 3alpha-hydroxysteroid + NAD(+) = a 3-oxosteroid + H(+) + NADH


name: (-)-matairesinol + O2 + reduced [NADPH--hemoprotein reductase] => (-)-pluviatolide + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + hexadecanoate + lanosterol => H2O + lanosteryl hexadecanoate


name: 1-O-(1Z)-hexadecenyl-2 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+)


name: (2S)-naringenin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (2S)-dihydrotricetin + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Danio rerio)


name: 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP => alizarin + UDP-alpha-D-glucose


name: AKT-phosphorylated FOXO3 translocates to cytosol (Sus scrofa)