name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Saccharomyces cerevisiae)


name: Phosphorylation of STAT1 at Ser727 (Rattus norvegicus)


name: NADH + O2 + rifampicin <=> H(+) + H2O + NAD(+) + rifampicin para-naphthoquinone carboxamide


name: CDP-alpha-D-glucose + D-glucose 6-phosphate => alpha,alpha-trehalose 6-phosphate + CDP + H(+)


name: 1,1-dichloroethene + AH2 <=> A + chloride + chloroethene + H(+)


name: Elongation of arachidonyl-CoA to docosatetraenoyl-CoA (Danio rerio)


name: ATP + biotin(in) + H2O => ADP + biotin(out) + H(+) + phosphate


name: SLC45A3 transports Glc from extracellular region to cytosol (Bos taurus)


name: ATP + L-aspartate + NH4(+) = ADP + H(+) + L-asparagine + phosphate


name: 3-hydroxybenzyl alcohol + benzoyl-CoA => 3-hydroxy-benzyl benzoate + CoA


name: PGH2 is isomerised to PGE2 by PTGES (Canis familiaris)


name: 6-deoxyerythronolide B + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> erythronolide B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin] => glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine


name: DKC1 binds SHQ1 (Dictyostelium discoideum)


name: 2 glutathione + H2O2 => glutathione disulfide + 2 H2O


name: chloride(out) + formate(in) => chloride(in) + formate(out)


name: L-arginine(in) + L-lysine(out) => L-arginine(out) + L-lysine(in)


name: SUMOylation of ING2 with SUMO1 (Gallus gallus)


name: CLPXP degrades mitochondrial matrix proteins (Homo sapiens)


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Bos taurus)


name: EP300 acetylates histone H2A, H2B, H3, H4 (Xenopus tropicalis)


name: Beclin-1 complex translocates to the ER (Mus musculus)


name: CoA + N(1)-acetyl-N(1)-hydroxyputrescine => acetyl-CoA + N-hydroxyputrescine


name: UBA1 adenylates ubiquitin in the cytosol (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + L-serine O-sulfate => H(+) + NH4(+) + pyruvate + sulfate


name: ISGylation of E2 conjugating enzymes (Drosophila melanogaster)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Xenopus tropicalis)


name: Interaction of Plectin with Integrin beta 4 (Rattus norvegicus)


name: LINC01139 facilitates PTK6 autophosphorylation (Mus musculus)


name: Formation of CDK4/6:CCND complexes (Drosophila melanogaster)


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Rattus norvegicus)


name: 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = 1-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+)


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)


name: Phosphorylated SMAD2/3 dissociates from TGFBR (Rattus norvegicus)


name: AH2 + alstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => A + O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine


name: GPI dimer isomerizes Fru(6)P to G6P (Homo sapiens)


name: COQ6 hydroxylates DHB (Rattus norvegicus)


name: MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Mus musculus)


name: 1-O-alkyl-sn-glycero-3-phosphate + an acyl-CoA => 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + CoA


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Sus scrofa)


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Bos taurus)


name: Cleavage of the signal peptide of Preproghrelin (Homo sapiens)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Bos taurus)


name: benzoyl-CoA + hexan-3-ol <=> CoA + hexan-3-yl benzoate


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)


name: H(+) + H2O + S-adenosyl-L-homocysteine => NH4(+) + S-inosyl-L-homocysteine


name: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4(+)


name: a 1-acyl-sn-glycero-3-phospholipid + a fatty acid + H(+) => a glycerophospholipid + H2O


name: H(+) + S-adenosyl-L-homocysteine + toralactone => nor-toralactone + S-adenosyl-L-methionine


name: HMIT co-transports myo-inositol with a proton (Schizosaccharomyces pombe)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Danio rerio)


name: H(+) + ipsdienone + NADH => (4R)-ipsdienol + NAD(+)


name: Within the IL-2R complex JAK3 phosphorylates JAK1 (Sus scrofa)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Canis familiaris)


name: SFTPA genes produce SFTPA proteins (Homo sapiens)


name: chlorophyllide a + H(+) + phytol => chlorophyll a + H2O


name: (E)-cinnamate + NH4(+) => L-phenylalanine


name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Homo sapiens)


name: CES2 hydrolyzes ASA- (Dictyostelium discoideum)


name: p-4Y-SIRPA:CD47 binds PTK2B (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + cholesterol = cholesteryl (9Z-octadecenoate) + CoA


name: GLB1 hydrolyses linker chain(2) (Sus scrofa)


name: HATs and coactivators are recruited to the CTSD gene (Canis familiaris)


name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Mus musculus)


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Mus musculus)


name: Plasma membrane resorption (Rattus norvegicus)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Drosophila melanogaster)


name: Interleukin-23 binds interleukin-23 receptor (Canis familiaris)


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Sus scrofa)


name: a ganglioside GM3 + N-acetyl-beta-D-galactosamine => a ganglioside GM2 + H2O


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Caenorhabditis elegans)


name: Activated FGFR2 binds FRS3 (Mus musculus)


name: CREBBP, EP300 acetylates NFE2L2 (Rattus norvegicus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Canis familiaris)


name: MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix (Canis familiaris)


name: Activation of CHEK1 at resected DNA DSBs (Mus musculus)


name: 5-amino-6-(D-ribitylamino)uracil + methylglyoxal <=> 5-(2-oxopropylideneamino)-6-(D-ribitylamino)uracil + H2O


name: OPN (osteopontin) degradation by MMP3, MMP7 (Mus musculus)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Plasmodium falciparum)


name: ATP + H2O + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(in) <=> ADP + H(+) + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate(out) + phosphate


name: H2O + L-kynurenine = anthranilate + H(+) + L-alanine


name: (2E,6E,10E)-geranylgeranyl diphosphate = cattleyene + diphosphate


name: Release of the SLBP independent Histone mRNA from the NPC (Canis familiaris)


name: UGT1A10 transfers GlcA from UDP-GlcA to GCTN (Dictyostelium discoideum)


name: epsilon-(gamma-L-glutamyl)-L-lysine => 5-oxo-L-proline + L-lysine


name: JAK2-activated MAPKs phosphorylate YBX1 (Canis familiaris)


name: Furin cleaves pro-protein Z to protein Z (Xenopus tropicalis)


name: 6-sulfo-alpha-D-quinovose + glycerol => 3-(6-sulfo-alpha-D-quinovosyl)glycerol + H2O


name: SLC29A1 transports RBV from extracellular region to cytosol (Homo sapiens)


name: STING binds cyclic GMP-AMP (Gallus gallus)


name: AKAP8L binds MLL1 complex (Gallus gallus)


name: Formation of alternative pathway C5 convertase (Mus musculus)


name: Association of procollagen type V (Homo sapiens)


name: 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Drosophila melanogaster)


name: HDAC8 deacetylates histones (Gallus gallus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate <=> 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: (+)-exo-beta-bergamotene + diphosphate => (2E,6E)-farnesyl diphosphate


name: protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity


name: D-ribose 2,5-bisphosphate + H(+) => alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O


name: scyllo-inosose => 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O


name: bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE (Homo sapiens)


name: ARHGAP35 stimulates RHOA GTPase activity (Mus musculus)


name: a D-galactosylceramide + H(+) + UDP => an N-acyl-sphingoid base + UDP-alpha-D-galactose


name: UDP-alpha-D-glucose + vancomycin aglycone => devancoaminyl-vancomycin + UDP


name: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO2 + NADH


name: ligand-activated transcription factor activity


name: 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+) => 1-hexanoyl-sn-glycero-3-phosphocholine + H2O


name: an N-acyl-L-alpha-aminoacyl-tRNA + H2O => a tRNA + an N-acyl-L-amino acid + H(+)


name: NTPDase1 hydrolyzes nucleoside triphosphates (Canis familiaris)


name: Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Drosophila melanogaster)


name: fumarate(out) + 3 Na(+)(out) => fumarate(in) + 3 Na(+)(in)


name: LTA4 is converted to EXA4 by ALOX15 (Dictyostelium discoideum)


name: ABHD6,12 hydrolyse 3AG (Drosophila melanogaster)


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Caenorhabditis elegans)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Gallus gallus)


name: GDP-alpha-D-glucose + H2O = D-glucose + GDP + H(+)


name: 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Schizosaccharomyces pombe)


name: Cortisol translocates from the mitochondrial matrix to the cytosol (Homo sapiens)


name: Formation of ADAR2  homodimer (Canis familiaris)


name: 1-O-tetradecylglycerone 3-phosphate + H(+) + hexadecanoate => 1-hexadecanoylglycerone 3-phosphate + tetradecan-1-ol


name: all-trans-retinol + O2 + reduced [NADPH--hemoprotein reductase] => all-trans-retinal + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 6alpha-hydroxy-28-norcastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxo-28-norcastasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: ATF5 translocates from the cytosol to the mitochondrial matrix (Homo sapiens)


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Gallus gallus)


name: 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Sus scrofa)


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Homo sapiens)


name: dibenzofuran + H(+) + NADH + O2 = biphenyl-2,2',3-triol + NAD(+)


name: KIR2DL1 interacting with HLA-C group 2 (Cw3) (Bos taurus)


name: mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Mus musculus)


name: 1-palmitoylglycerone phosphate + hexadecanol => O-hexadecylglycerone phosphate + palmitate (Rattus norvegicus)


name: ATP + H2O + phosphonate(out) <=> ADP + H(+) + phosphate + phosphonate(in)


name: IL37, IL37(?-218) translocates from cytosol to extracellular region (Homo sapiens)


name: 6-deoxy-6-sulfo-D-gluconate + H(+) => 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H2O


name: a ganglioside GQ1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GP1calpha (d18:1(4E)) + CMP + H(+)


name: HMGCR dimer reduces bHMG-CoA to MVA (Danio rerio)


name: (8S)-annullatin E + dimethylallyl diphosphate <=> (8S)-annullatin J + diphosphate


name: diphosphate + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine => CTP + H(+) + N(5)-phospho-L-glutamine


name: dTDP-alpha-D-fucose + NADP(+) => dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH


name: GLUT1 tetramer binds 4xATP (Gallus gallus)


name: Dopamine synaptic vesicle docking and priming (Drosophila melanogaster)


name: IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Homo sapiens)


name: SUMOylation of Histone H4 with SUMO1 (Plasmodium falciparum)


name: (5R)-5-hydroxy-L-lysine + GTP = (5R)-5-phosphooxy-L-lysine + GDP + H(+)


name: 4-guanidinobutanamide + H2O = 4-guanidinobutanoate + NH4(+)


name: 2-methoxy-6-all-trans-heptaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = 6-methoxy-3-methyl-2-all-trans-heptaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: (S)-3-(imidazol-5-yl)lactate + NADP(+) = 3-(imidazol-5-yl)pyruvate + H(+) + NADPH


name: HSP90-dependent ATP hydrolysis promotes release of ESR:ESTG from chaperone complex (Homo sapiens)


name: TRIKA2 binds K63polyUb-TRAF6 oligomer (Canis familiaris)


name: The SHC1:SHIP1 complex is stabilized by GRB2 (Gallus gallus)


name: a ganglioside GD1c (d18:1(4E)) + CMP + H(+) => a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: glycine + hydrogen sulfide + NAD(+) <=> ADP-5-ethyl-4-methylthiazole-2-carboxylate + H(+) + 3 H2O + nicotinamide


name: [amino-group carrier protein]-C-terminal-L-glutamate + ATP + L-glutamate <=> [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ADP + H(+) + phosphate


name: (2E,6E,10E)-geranylgeranyl diphosphate = (+)-kolavenyl diphosphate


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)


name: (R)-pantothenate(in) + Na(+)(in) <=> (R)-pantothenate(out) + Na(+)(out)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O => (14R,15R)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: Hydroperoxyl enters the bacterium (Homo sapiens)


name: (6Z,9Z,12Z)-octadecatrienoate + H2O => (10S)-hydroxy-(6Z,12Z)-octadecadienoate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Danio rerio)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycerol + H(+) + phosphocholine


name: AKT1 phosphorylates NOTCH4 (Caenorhabditis elegans)


name: a 3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP(+) => a 4alpha-methyl-3-oxosteroid + CO2 + NADPH


name: H(+) + phosphoenolpyruvate + sulfite => (2R)-O-phospho-3-sulfolactate


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + succinate


name: dehydroepiandrosterone 3-sulfate(in) + glutarate(out) => dehydroepiandrosterone 3-sulfate(out) + glutarate(in)


name: Recruitment of SYK to phosphorylated ITAMs (Homo sapiens)


name: ATP + N-acetyl-D-glucosamine <=> ADP + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate


name: an R-cob(III)alamin + apo-[alkylcobalamin reductase] + glutathione => an S-substituted glutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+)


name: Phosphorylated OPTN translocates to the nucleus (Bos taurus)


name: Cleavage of Procaspase‑9 to caspase‑9 (Bos taurus)


name: acetate + CO2 + Na(+)(out) => H(+) + malonate + Na(+)(in)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Sus scrofa)


name: VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization (Bos taurus)


name: Activated FGFR4 binds PLCG1 (Sus scrofa)


name: Transport of MHC heterotrimer to ER exit site (Sus scrofa)


name: protein-arginine omega-N monomethyltransferase activity


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Homo sapiens)


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Homo sapiens)


name: ATP + cholate(in) + glutathione(in) + H2O => ADP + cholate(out) + glutathione(out) + H(+) + phosphate


name: CYP21A2 21-hydroxylates PROG (Sus scrofa)


name: a 5'-end guanosine-5'-diphospho-5'-(2'-deoxyribonucleoside)-DNA + H2O => a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + GMP + 2 H(+)


name: RAD51B:RAD51C binds single-stranded DNA (Bos taurus)


name: CoA + H(+) + prostaglandin F2alpha => H2O + prostaglandin F2alpha-CoA


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + CTP + H(+) = CDP-2,3-bis-O-(geranylgeranyl)-sn-glycerol + diphosphate


name: SOS binds Grb2 bound to pFAK:NCAM1 (Canis familiaris)


name: JAK2 is phosphorylated, activated (Bos taurus)


name: MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Rattus norvegicus)


name: Activation of STAT5a/b by JAK2 (Gallus gallus)


name: alpha-D-glucose 6-phosphate <=> beta-D-fructose 6-phosphate


name: IL17RD binds p-2S MAP2Ks and MAPKs (Gallus gallus)


name: 1-phospho-alpha-D-glucuronate + H(+) + UTP => diphosphate + UDP-alpha-D-glucuronate


name: FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Homo sapiens)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Drosophila melanogaster)


name: 5,6-dihydrothymine + H2O => beta-ureidoisobutyrate (Caenorhabditis elegans)


name: CO2 + CoA + olivetol => 3,5,7-trioxododecanoyl-CoA


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Bos taurus)


name: androstan-3alpha,17beta-diol + NAD(+) => 17beta-hydroxyandrostanone + H(+) + NADH


name: CCND1 binds RUNX3 and displaces EP300 (Drosophila melanogaster)


name: (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] => 1-aci-nitro-2-(phenyl)ethane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADPH + O2 + phenylacetone = benzyl acetate + H2O + NADP(+)


name: Lysosomal degradation of gap junction plaques (Gallus gallus)


name: FOXM1 binds CENPF promoter (Homo sapiens)


name: CYP4A11 12-hydroxylates DDCX (Mus musculus)


name: ATP + chenodeoxycholate + CoA = AMP + chenodeoxycholoyl-CoA + diphosphate


name: H(+) + N,N-dihydroxy-L-dihomomethionine => (E)-5-(methylsulfanyl)pentanal oxime + CO2 + H2O


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Homo sapiens)


name: H2O2 + N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine => H2O + N(1)-acetylspermine + O2


name: (2E)-geranyl diphosphate = diphosphate + gamma-terpinene


name: Phosphorylation of Bcl10 (Canis familiaris)


name: dihydro-ML-236C carboxylate + O2 + reduced [NADPH--hemoprotein reductase] <=> 3alpha-hydroxy-3,5-dihydro-ML-236C carboxylate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Homo sapiens)


name: oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor


name: Loading of antigen peptide onto MHC class I molecule (Danio rerio)


name: ORC6 binds KPNA1 or KPNA6 (Homo sapiens)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Sus scrofa)


name: formyl-CoA + pentadecanal => (2R)-hydroxyhexadecanoyl-CoA


name: (R)-4'-phosphopantothenate + H2O => (R)-pantothenate + phosphate


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Mus musculus)


name: RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes (Canis familiaris)


name: PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)


name: H(+) + imidazole-4-acetate + NADH + O2 = 5-hydroxyimidazole-4-acetate + H2O + NAD(+)


name: H(+) + L-2-aminoadipyl-[LYS2 peptidyl-carrier protein] + NADPH => (S)-2-amino-6-oxohexanoate + holo-[LYS2 peptidyl-carrier protein] + NADP(+)


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Bos taurus)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Homo sapiens)


name: TRAF6 is K63 poly-ubiquitinated (Homo sapiens)


name: [(3R)-hydroxybutanoate](n) + H2O => (R)-3-hydroxybutanoate + [(3R)-hydroxybutanoate](n-1) + H(+)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Rattus norvegicus)


name: JAK1 binds IL4R in IL4-bound IL4R1 (Rattus norvegicus)


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate = CO2 + deoxyviolacein + 2 H2O + NADP(+)


name: (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: Release of eIF4E from the inactive eIF4E:4E-BP complex  (Dictyostelium discoideum)


name: Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL (Homo sapiens)


name: ADP-dependent NAD(P)H-hydrate dehydratase activity


name: (2E,6E)-farnesal + H2O2 + L-cysteine => H2O + O2 + S-(2E,6E)-farnesyl-L-cysteine


name: IL1R1 binds IL1R1 inhibitors (Mus musculus)


name: ARMS is phosphorylated by active TrkA receptor (Gallus gallus)


name: CD22 binds B-cell receptor (Rattus norvegicus)


name: MLCL is acylated to CL by LCLAT1 (ER) (Canis familiaris)


name: Degradation of ubiquitinated SMAD2 (Gallus gallus)


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Gallus gallus)


name: CYCS:APAF1 binds procaspase-9 (Mus musculus)


name: a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GD1a (d18:1(4E)) + H2O


name: CoA + ethyl butanoate => butanoyl-CoA + ethanol


name: a triacyl-sn-glycerol + H2O => a 1,2-diacyl-sn-glycerol + a fatty acid + H(+)


name: O2 + proatranorin I + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin IV


name: Defective ABCB4 does not transport PC from plasma membrane to extracellular region (Homo sapiens)


name: Collagen type XII degradation by MMP12 (Gallus gallus)


name: XYLB phosphorylates D-xylulose (Xenopus tropicalis)


name: a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate <=> a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose 6-phosphate + H(+)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Sus scrofa)


name: D-mannose 6-phosphate + H2O + phosphoenolpyruvate <=> 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate


name: IL21 receptor STAT phosphorylation (Sus scrofa)


name: O2 + tetracenomycin F1 = H(+) + H2O + tetracenomycin D3


name: ADP-Ribosylation of HNP-1 (Rattus norvegicus)


name: (2R,5R)-isopulegone + NADP(+) => (6R)-isopiperitenone + H(+) + NADPH


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Bos taurus)


name: AHRR binds ARNT (Drosophila melanogaster)


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Mus musculus)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: 4'-hydroxyacetophenone + H(+) + NADPH + O2 = 4-acetoxyphenol + H2O + NADP(+)


name: SHPK phosphorylates Sedo to Sedo7P (Caenorhabditis elegans)


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Gallus gallus)


name: 3'-deoxy-3',4'-didehydro-GTP + 5'-deoxyadenosine + A + H(+) + H2O + L-methionine => AH2 + GTP + S-adenosyl-L-methionine


name: (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate => (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate + 7 diphosphate


name: acetyl-CoA + N(6)-methyl-L-lysyl-[histone] => CoA + H(+) + N(6)-acetyl-N(6)-methyl-L-lysyl-[histone]


name: H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol <=> a fatty acid + H(+) + long chain 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: MITF-M-dependent expression of CDKN2A gene product 16INK4A  (Homo sapiens)


name: H(+) + L-methionyl(44)-[F-actin] + NADPH + O2 => H2O + L-methionyl(44)-(R)-S-oxide-[F-actin] + NADP(+)


name: indole + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + indolin-2-one + oxidized [NADPH--hemoprotein reductase]


name: TIMM23 SORT inserts proteins into inner membrane (Homo sapiens)


name: SCF-FBXL7 ubiquitinates AURKA (Xenopus tropicalis)


name: acetaldehyde + 2 Fe(III)-[cytochrome c] + H2O => acetate + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: BMP2 binds to the receptor complex (Gallus gallus)


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)


name: [(1->4)-beta-D-glucosyl](n) + GDP-alpha-D-glucose <=> [(1->4)-beta-D-glucosyl](n+1) + GDP + H(+)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Gallus gallus)


name: 3,6,8,9-tetrahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H(+) + NADPH + O2 = 2,3,6,8,9-pentahydroxy-1-oxo-3-(2-oxopropyl)-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + H2O + NADP(+)


name: LDHAL6B reduces PYR to LACT (Canis familiaris)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Dictyostelium discoideum)


name: 2 Fe(III)-[cytochrome c] + hexan-1-ol => 2 Fe(II)-[cytochrome c] + 2 H(+) + hexanal


name: AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine (Homo sapiens)


name: SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region (Sus scrofa)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Caenorhabditis elegans)


name: PIAS2,3,4 SUMOylate RORA with SUMO1 (Gallus gallus)


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Mus musculus)


name: DHRS7B reduces GO3P to HXDG3P (Xenopus tropicalis)


name: beta-D-gentiobiosyl crocetin + UDP-alpha-D-glucose <=> beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP


name: ATP + holo-[peptidyl-carrier protein] + L-tryptophan => AMP + diphosphate + L-tryptophyl-[peptidyl-carrier protein]


name: N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + H(+) + UDP


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Caenorhabditis elegans)


name: 2 cob(II)inamide-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] => 2 cob(I)inamide-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein]


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + zeinoxanthin = H(+) + H2O + lutein + oxidized [NADPH--hemoprotein reductase]


name: beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-D-glucose + GDP + H(+) => GDP-beta-L-fucose + lactose


name: aldehyde dehydrogenase [NAD(P)+] activity


name: Recruitment of  RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Homo sapiens)


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate = etheroleate + H2O


name: 1-acyl LPI is acylated to PI by MBOAT7 (Canis familiaris)


name: H2O + L-glutamine + O2 = 2-oxoglutaramate + H2O2 + NH4(+)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Drosophila melanogaster)


name: fumarate + L-aspartate => iminosuccinate + succinate


name: scutellarin + UDP => scutellarein + UDP-alpha-D-glucuronate


name: 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate


name: (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + phosphate => (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + H2O


name: 2-oxoglutarate + 7-deoxycylindrospermopsin + O2 = 7-epi-cylindrospermopsin + CO2 + succinate


name: Glucagon-like Peptide 1 is secreted from intestinal L cells (Mus musculus)


name: 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Mus musculus)


name: 3-hydroxy-3-methylglutarate + malonyl-CoA => (3S)-hydroxy-3-methylglutaryl-CoA + malonate


name: STAB1 (FEEL-1) binds ligands (Mus musculus)


name: Neogenin:Netrin-3 binds CDO complex (Homo sapiens)


name: F2R:ARRB2 binds MAPKs, SRC-1 (Caenorhabditis elegans)


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-choloyl-4'-phosphopantetheine => choloyl-CoA + H2O


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Caenorhabditis elegans)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate


name: CRHR2-2 binds CRH,UCN,UCN2,UCN3 (Sus scrofa)


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Bos taurus)


name: ECHS1 hydrates methacrylyl-CoA (Xenopus tropicalis)


name: (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + sarcosine => (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + H(+) + N,N-dimethylglycine + oxidized [electron-transfer flavoprotein]


name: atranorin + S-adenosyl-L-homocysteine => proatranorin III + S-adenosyl-L-methionine


name: H2O + neryl diphosphate => diphosphate + nerol


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: TLE oligomerizes (Caenorhabditis elegans)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Schizosaccharomyces pombe)


name: Recruitment of Plk1 to centrosomes (Canis familiaris)


name: FRS2 is phosphorylated by active TrkA receptor (Rattus norvegicus)


name: myo-inositol + S-adenosyl-L-methionine = 1D-4-O-methyl-myo-inositol + H(+) + S-adenosyl-L-homocysteine


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Caenorhabditis elegans)


name: Recruitment of SET1 methyltransferase complex (Drosophila melanogaster)


name: SUMOylation of DDX17 with SUMO1 (Bos taurus)


name: acetoin + CO2 => acetaldehyde + H(+) + pyruvate


name: Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching (Homo sapiens)


name: UMPS dimer decarboxylates OMP to UMP (Mus musculus)


name: 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase => a purine 2'-deoxy-D-ribonucleoside + phosphate


name: CDC42 GEFs activate CDC42 (Canis familiaris)


name: FSTL3 binds Activin (Drosophila melanogaster)


name: p-PKR dimer phosphorylates MAPT (Mus musculus)


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Rattus norvegicus)


name: ent-cassa-12,15-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> ent-11beta-hydroxycassa-12,15-diene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Xenopus tropicalis)


name: Translocation of caspase-3 to the nucleus (Rattus norvegicus)


name: (8R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: (12R,13S)-epoxy-(9Z)-octadecenoate + O2 => (12R,13S)-epoxy-(10R)-hydroperoxy-(8E)-octadecenoate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a sterol = a 1-acyl-sn-glycero-3-phosphocholine + a sterol ester


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-leucine + O2 <=> (2S)-4-methyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanoate + H(+) + H2O2


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA => 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronate + UDP => (5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate


name: D-glucose(in) + H(+)(in) => D-glucose(out) + H(+)(out)


name: p-DAPP1 (p-BAM32) binds PLCG2 (Sus scrofa)


name: DHFR2 reduces FOLA to DHF (Drosophila melanogaster)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Xenopus tropicalis)


name: IL6:IL6R-2 binds IL6ST:JAK1, JAK2, (TYK2) (Homo sapiens)


name: NUMB:ITCH bind and ubiquitnate GLI1 (Rattus norvegicus)


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O <=> a fatty acid + a monoacyl-sn-glycero-3-phosphocholine + H(+)


name: AMP + diphosphate + H(+) + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine) => ATP + N(1)-(3,4-dihydroxybenzoyl)-N(8)-citryl-spermidine + spermidine


name: HDHD1:Mg2+ dephosphorylates PURIDP (Xenopus tropicalis)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = a 1,2-diacyl-sn-glycerol + H(+) + sn-glycerol 3-phosphate


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Mus musculus)


name: GTP + H2O = 7,8-dihydroneopterin 2',3'-cyclic phosphate + diphosphate + formate + H(+)


name: H(+)(in) + L-alanyl-L-valine(in) => H(+)(out) + L-alanyl-L-valine(out)


name: structural constituent of postsynaptic density


name: H(+) + NADPH + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose => NADP(+) + UDP-N-acetyl-alpha-D-quinovosamine


name: N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + heptadecanoyl-CoA + O2 => 2-hydroxyheptadecanoyl-CoA + CO2 + succinate


name: 2 Na(+)(in) + taurocholate(in) => 2 Na(+)(out) + taurocholate(out)


name: 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + ribostamycin <=> gamma-L-glutamyl-butirosin B + H(+) + holo-[BtrI ACP]


name: (3E)-4,8-dimethylnona-1,3,7-triene + but-3-en-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (3S,6E)-nerolidol + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-acyl LPE is acylated to PE by LPEAT (Schizosaccharomyces pombe)


name: Formation of the SET1A complex (Sus scrofa)


name: 2,4-dichlorophenol + H(+) + NADPH + O2 => 3,5-dichlorocatechol + H2O + NADP(+)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + tetradecanoyl-CoA => 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA


name: SLC25A12,13 exchange L-Glu and L-Asp (Xenopus tropicalis)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Dictyostelium discoideum)


name: 3-hydroxy-3-(4-O-beta-D-glucosyl-3-methoxyphenyl)propanoate = 4-O-beta-D-glucosyl-vanillin + acetate


name: G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Dictyostelium discoideum)


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Gallus gallus)


name: diuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3-(3,4-dichlorophenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: miR-613 binds to the 3'UTR of the NR1H3 mRNA (Homo sapiens)


name: Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Homo sapiens)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Bos taurus)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Sus scrofa)


name: Inner coat assembly and cargo binding (Mus musculus)


name: XPO1 binds the beta-catenin:CBY complex (Gallus gallus)


name: CYP3A7 can 6beta-hydroxylate testosterone (Mus musculus)


name: Activation of Ca permeable AMPA receptors (Homo sapiens)


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Xenopus tropicalis)


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Drosophila melanogaster)


name: GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Xenopus tropicalis)


name: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Mus musculus)


name: Acireductone is oxidized to MOB (Xenopus tropicalis)


name: ATP + CoA + tetradecanedioate = AMP + diphosphate + tetradecanedioyl-CoA


name: SLC46A1 transports FOLA from extracellular region to cytosol (Danio rerio)


name: ent-cassa-12,15-dien-2beta,3beta-ol + O2 + reduced [NADPH--hemoprotein reductase] = ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: acetoacetate + butanoyl-CoA => acetoacetyl-CoA + butanoate


name: 3,4-dihydroxybenzoate + 2 H(+) + NADPH + O2 = benzene-1,2,4-triol + CO2 + H2O + NADP(+)


name: Activated FGFR2 binds PLCG1 (Mus musculus)


name: N-carbamoyl-D-amino acid hydrolase activity


name: RAC2 GAPs stimulate RAC2 GTPase activity (Mus musculus)


name: 3-dehydro-4alpha-methylzymosterol + CO2 + NADH => 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NAD(+)


name: a carboxylate + 2 H(+) + NADH => an aldehyde + H2O + NAD(+)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Dictyostelium discoideum)


name: Monoubiquitination of N-myristoyl GAG polyprotein (Homo sapiens)


name: NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Rattus norvegicus)


name: 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP => 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: lactose + H2O => D-glucose + D-galactose (Xenopus tropicalis)


name: RAC3 GAPs stimulate RAC3 GTPase activity (Bos taurus)


name: PP-IP4 is dephosphorylated to I(1,3,4,5,6)P5 by NUDT4 in the cytosol (Mus musculus)


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Bos taurus)


name: SESN1,2,3 bind overoxidized PRDX1 (Canis familiaris)


name: p-EPHs bind SRC,FYN,YES,LYN (Homo sapiens)


name: L-cysteinyl-[protein] + octadecanoyl-CoA <=> CoA + S-octadecanoyl-L-cysteinyl-[protein]


name: D-cellobiono-1,5-lactone + H2O = 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)


name: a 7(1)-hydroxybacteriochlorophyllide c + H2O + S-adenosyl-L-methionine = 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide c + H(+) + L-methionine


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-(1Z)-alkenyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: ATP + glutathione(in) + glycochenodeoxycholate(in) + H2O = ADP + glutathione(out) + glycochenodeoxycholate(out) + H(+) + phosphate


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphate <=> 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: A + dihydropyriculol <=> AH2 + pyriculol


name: Factor Xa inhibitors bind Va:Xa (Mus musculus)


name: 11-oxo-beta-amyrin + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> glycyrrhetinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: transmembrane receptor protein serine/threonine kinase activity


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Homo sapiens)


name: (5Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + A + 2 H2O => (11Z,14Z,17Z)-eicosatrienoyl-CoA + AH2 + O2


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Xenopus tropicalis)


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Gallus gallus)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O => (N(2),N(2),N(7))-trimethyl-GMP + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+)


name: (R)-lipoate + ATP + H(+) <=> (R)-lipoyl-5'-AMP + diphosphate


name: 1,2-dihexadecanoyl-sn-glycerol + ATP => 1,2-dihexadecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Mus musculus)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + NAD(+) <=> androst-4-ene-3,11,17-trione + H(+) + NADH


name: a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + 2 S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + H(+) + 2 S-adenosyl-L-homocysteine


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Dictyostelium discoideum)


name: dCDP + H(+) + phosphoenolpyruvate => dCTP + pyruvate


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Neuromedin-U receptors bind neuromedins U, S (Bos taurus)


name: GP369 inhibits activation of amplified FGFR2 signaling (Homo sapiens)


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Bos taurus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + CO2 + NADH + NH4(+) => (6S)-5,6,7,8-tetrahydrofolate + glycine + NAD(+)


name: MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Dictyostelium discoideum)


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Xenopus tropicalis)


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Drosophila melanogaster)


name: keto-L-sorbose + NADP(+) => 5-dehydro-D-fructose + H(+) + NADPH


name: (2S)-3-sulfopropanediol + NAD(+) = (2S)-3-sulfolactaldehyde + H(+) + NADH


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+) => a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate


name: 13-(9Z-hexadecenoyloxy)-octadecanoate + H2O <=> (9Z)-hexadecenoate + 13-hydroxy-octadecanoate + H(+)


name: TFPA2A homodimer and NPM1 bind the NOP2 gene promoter (Homo sapiens)


name: ERK1/2-activated AP1 complex binds KDM6B promoter (Homo sapiens)


name: 2-oxoglutarate + chloride + H(+) + hapalindole U + O2 = CO2 + H2O + hapalindole G + succinate


name: VDR agonists bind VDR (Rattus norvegicus)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Gallus gallus)


name: 2-hydroxy-3-methylhexadecanoyl-CoA + CO2 + succinate => 2-oxoglutarate + 3-methylhexadecanoyl-CoA + O2


name: an N-acetylarylalkylamine + H2O => acetate + an aralkylamine


name: 4 PBGs bind to form HMB (Schizosaccharomyces pombe)


name: lanosterol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: FA anion diffuses laterally to UCP (Sus scrofa)


name: IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Homo sapiens)


name: [protein]-C-terminal-L-glutamine + H2O => [protein]-C-terminal-L-glutamate + NH4(+)


name: (9Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: EBP isomerizes ZYMSTNL to LTHSOL (Mus musculus)


name: TRAF6 binding leads to IRAK1:TRAF6 release (Mus musculus)


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Sus scrofa)


name: Formation of the preholothymoproteasome (Drosophila melanogaster)


name: Activated glucocorticoid receptor binds NPAS4 gene promoter (Homo sapiens)


name: HRH2 binds HRH2 antagonists (Sus scrofa)


name: (S)-malyl N-acetyl-alpha-D-glucosaminide + H(+) + UDP => (S)-malate + UDP-N-acetyl-alpha-D-glucosamine


name: Degradation of ubiquitinated SMAD2 (Drosophila melanogaster)


name: EXT1:EXT2 transfer GlcNAc to the heparan chain (Sus scrofa)


name: (R)-linalool + diphosphate => (2E)-geranyl diphosphate + H2O


name: (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O => (3R)-hydroxy-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA


name: carbendazim + H2O <=> H(+) + methanol + N-(1H-1,3-benzodiazol-2-yl)carbamate


name: RHOV binds effectors at the plasma membrane (Bos taurus)


name: VMAT1/2 can mediate the transport of biogenic amines (Canis familiaris)


name: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => calcitetrol + H2O + 2 oxidized [adrenodoxin]


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Rattus norvegicus)


name: Co(I)-[quaternary-amine-specific corrinoid protein] + H(+) + L-proline betaine <=> methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + N-methyl-L-proline


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: (2E,6E)-farnesyl diphosphate => (+)-valencene + diphosphate


name: IQGAPs bind CALM1 (Schizosaccharomyces pombe)


name: TRPM5 transports Na+ from the extracellular region to the cytosol (Homo sapiens)


name: SUMOylation of TFAP2C with SUMO1 (Caenorhabditis elegans)


name: albendazole + O2 + reduced [NADPH--hemoprotein reductase] = albendazole S-oxide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)


name: MAPK12 phosphorylates PTPN3 (Drosophila melanogaster)


name: Activated thrombin (factor IIa) cleaves PAR3,4, activating them (Gallus gallus)


name: dibenzo-p-dioxin + NADH + O2 = 2,2',3-trihydroxydiphenyl ether + H(+) + NAD(+)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Canis familiaris)


name: (R)-2-hydroxyglutarate + FAD + H(+) <=> 2-oxoglutarate + FADH2


name: a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycerol <=> a triacyl-sn-glycerol + glycerol


name: IRAK interacts with TRAF6 (Rattus norvegicus)


name: p-AKT2 phosphorylates RGC2 (Homo sapiens)


name: cytidine(3782) in 28S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(3782) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: polymyxin transmembrane transporter activity


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Bos taurus)


name: DELE1(143-515) is released into the cytosol (Danio rerio)


name: NEIL3 cleaves 5-guanidinohydantoin (Bos taurus)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Homo sapiens)


name: S100A8:S100A9 binds Mn2+ (Xenopus tropicalis)


name: DNA polymerase epsilon binds at the origin (Saccharomyces cerevisiae)


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Bos taurus)


name: PAK1:ARHGEF6 complex binds G-protein beta-gamma complex (Mus musculus)


name: 8-O-methylsterigmatocystin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => aflatoxin B1 + CO2 + 2 H(+) + H2O + methanol + 2 oxidized [NADPH--hemoprotein reductase]


name: TCF/LEF binds WNT promoters (Homo sapiens)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + maniladiol + oxidized [NADPH--hemoprotein reductase]


name: Autoglucosylation of GYG1 complexed with GYS1-a (Canis familiaris)


name: 1-O-(trans-sinapoyl)-beta-D-glucose + choline = D-glucose + O-sinapoylcholine


name: ALOX5 oxidises EPA to 5-HEPE (Homo sapiens)


name: 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Saccharomyces cerevisiae)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Caenorhabditis elegans)


name: FMO2:FAD:Mg2+ S-oxidises MTZ (Caenorhabditis elegans)


name: ACLY tetramer transforms CIT to Ac-CoA (Mus musculus)


name: SORD oxidizes D-sorbitol to Fru (Mus musculus)


name: LGI4 binds ADAM22,23,11 (Rattus norvegicus)


name: TBC1D3 associates with RAB5 (Homo sapiens)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate => 1D-myo-inositol 1,3,4,6-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate


name: Association of Cyclin A with the APC/C (Canis familiaris)


name: EP1 subtype prostaglandin E2 receptor binding


name: PDPK1 phosphorylates PKN1,2,3 (Rattus norvegicus)


name: H2O + N-(9Z-octadecenoyl)-sphing-4-enine => (9Z)-octadecenoate + sphing-4-enine


name: Caspase-8 and FLIP(L) processing at TNFR signaling complex (Sus scrofa)


name: D-serine(in) + Na(+)(in) => D-serine(out) + Na(+)(out)


name: CNIH1 binds TFGA and AREG precursors (Sus scrofa)


name: SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ (Drosophila melanogaster)


name: NPC2 transfers CHOL to NPC1 (Dictyostelium discoideum)


name: Release of 40S and 60S subunits from the 80S ribosome  (Schizosaccharomyces pombe)


name: N-hydroxy-L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Activated MET recruits GRB2-1:SOS1 (Canis familiaris)


name: CYP24A1 24-hydroxylates CTL (Bos taurus)


name: RNA polymerase I general transcription initiation factor activity


name: 3 H(+) + NADPH + O2 + 2 rubrofusarin B = 2 H2O + NADP(+) + nigerone


name: H(+) + N,N-dihydroxy-L-tetrahomomethionine => (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Caenorhabditis elegans)


name: Recruitment of CstF to the CPSF Bound Pre-mRNA (Homo sapiens)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Danio rerio)


name: IL37(?-218):p-S423,S425-SMAD3 translocates to the nucleus (Homo sapiens)


name: heptadecasphing-4-enine + tetracosenoyl-CoA => CoA + H(+) + N-tetracosenoyl-heptadecasphing-4-enine


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Dictyostelium discoideum)


name: Loss of Rrn3 from RNA Polymerase I promoter escape complex (Mus musculus)


name: (2S,4S,5S)-2-amino-6-(3,4-dihydroxyphenyl)-4-hydroxy-5-(methylamino)hexanoyl-[peptidyl-carrier protein] + O2 <=> (2S,4S)-2-amino-4-[(3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl]-4-hydroxybutanoyl-[peptidyl-carrier protein] + H2O2


name: SIRT5 deacetylates Cytochrome C (Sus scrofa)


name: 4,4-dihydroxy-all-trans-beta-carotene + A + H2O => 4-hydroxy-all-trans-beta-carotene + AH2 + O2


name: CANDI binds CUL1 (Schizosaccharomyces pombe)


name: Collagen type XV restin release (Mus musculus)


name: SLC35D2 exchanges UDP-D-glucose for UMP (Xenopus tropicalis)


name: Interaction of GPVI and FceRI gamma (Mus musculus)


name: OPTN binds polyUb-RIPK1 within the TNFR1 complex (Sus scrofa)


name: TBC1D25 (OATL1) binds ATG8 homologues (Bos taurus)


name: [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose => [(1->4)-alpha-D-glucosyl](n+1) + ADP + H(+)


name: Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Drosophila melanogaster)


name: trans-2-enoyl-CoA reductase (NADPH) activity


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Xenopus tropicalis)


name: acetylcholine + H2O <=> acetate + choline + H(+)


name: a ganglioside GD1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GT1balpha  (d18:1(4E)) + CMP + H(+)


name: D-maltobiono-1,5-lactone + H2O = D-maltobionate + H(+)


name: eNoSC dimethylates histone H3 at lysine-9 (Canis familiaris)


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Danio rerio)


name: (S)-ureidoglycolate => glyoxylate + urea


name: DHODH:FMN binds DHODH inhibitors (Drosophila melanogaster)


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Canis familiaris)


name: Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)


name: P4HB mediates disulfide bond formation in Proinsulin (Sus scrofa)


name: gibberellin A9 + S-adenosyl-L-methionine <=> O-methyl gibberellin A9 + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + L-gamma-glutamyl-L-propargylglycine + O2 = CO2 + L-gamma-glutamyl-(3R)-L-beta-ethynylserine + succinate


name: ATP + H(+) + octadecanoate <=> diphosphate + octadecanoyl-AMP


name: ADP + cob(II)yrinate c monoamide + H(+) + L-glutamate + phosphate => ATP + cob(II)yrinate + H2O + L-glutamine


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Bos taurus)


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 => (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate


name: ADAP1 gene expression is inhibited by ERBB4s80 (Homo sapiens)


name: NAALADases hydrolyse NAAG (Saccharomyces cerevisiae)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxy-fatty acyl)-dihydroceramide = a 1,2-diacyl-sn-glycerol + inositol-1-phospho-N-(2-hydroxy-fatty acyl)-dihydroceramide


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine => an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 25-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) (Canis familiaris)


name: H(+) + hydroxylamine + L-asparagine => beta-L-aspartylhydroxamate + NH4(+)


name: (R)-carnitine + 2-methylpropanoyl-CoA => CoA + O-isobutanoyl-(R)-carnitine


name: APOE gene transcription is stimulated by ERBB4s80 (Homo sapiens)


name: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Drosophila melanogaster)


name: ESTG stimulates GTP exchange on GPER:heterotrimeric G-protein s (Xenopus tropicalis)


name: oxalate + oxidized 2[4Fe-4S]-[ferredoxin] <=> 2 CO2 + reduced 2[4Fe-4S]-[ferredoxin]


name: (2E)-geranyl diphosphate <=> alpha-pinene + diphosphate


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Xenopus tropicalis)


name: Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR recruit GRB2:SOS1 through SHC1  (Homo sapiens)


name: a ribonucleoside 5'-triphosphate + phytyl phosphate <=> a ribonucleoside 5'-diphosphate + phytyl diphosphate


name: monoatomic cation:bicarbonate symporter activity


name: GDP + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n+1) + phosphate => GTP + L-glutamate + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: BRAP binds KSR1:MARK3 (Rattus norvegicus)


name: 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + H(+) + S-adenosyl-L-homocysteine => 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + S-adenosyl-L-methionine


name: PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Canis familiaris)


name: phycocyanobilin-L-cysteinyl(155)-[C-phycocyanin beta-subunit] <=> (2R,3E)-phycocyanobilin + apo-L-cysteinyl(155)-[C-phycocyanin beta-subunit]


name: GSDMD (1-275) binds bacterial cardiolipin (Canis familiaris)


name: ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA (Danio rerio)


name: Deubiquitination of RNF41 by P-USP8 (Dictyostelium discoideum)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Canis familiaris)


name: 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + UDP-alpha-D-glucose <=> 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-seryl-[protein] + H(+) + UDP


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine <=> a lipid A disaccharide + H(+) + UDP


name: PEX5S,L:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Schizosaccharomyces pombe)


name: 2-oxopentanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminopentanoate


name: (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate = 5-(methylsulfanyl)pentanenitrile + H(+) + sulfate + sulfur


name: ATP + H2O + Na(+)(in) = ADP + H(+) + Na(+)(out) + phosphate


name: copper-nicotianamine transmembrane transporter activity


name: AH2 + dehydroprobetaenone I <=> A + probetaenone I


name: an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H(+) + nicotinamide => a thymidine in DNA + NAD(+)


name: BPI binds LPS on the bacterial surface (Mus musculus)


name: STAT4 binds IL12RB2:IL12RB2 (Gallus gallus)


name: 3-aminopropanal + H2O2 + spermidine => H2O + O2 + spermine


name: ADP + H(+) + phosphate + pravastatin(out) => ATP + H2O + pravastatin(in)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O => a 2-acyl-sn-glycerol 3-phosphate + a fatty acid + H(+)


name: Formation of the pre-incision complex in GG-NER (Schizosaccharomyces pombe)


name: ERBB4s80:ESR1 binds ERBB4 gene promoter (Homo sapiens)


name: PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 (Rattus norvegicus)


name: Syndecans 1, 2, 4, (3) bind FGF2 (Danio rerio)


name: 3-hydroxy-2-methylpyridine-5-carboxylate + CO2 => 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Bos taurus)


name: 2 cornusiin E + 2 H2O => O2 + 4 tellimagrandin II


name: ryanodine-sensitive calcium-release channel activity involved in regulation of postsynaptic cytosolic calcium levels


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Bos taurus)


name: PMM1,2 isomerise Man6P to Man1P (Dictyostelium discoideum)


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Homo sapiens)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Rattus norvegicus)


name: L-glutamine(in) + Na(+)(in) = L-glutamine(out) + Na(+)(out)


name: 1-O-alkyl-sn-glycero-3-phosphate + a fatty acid + H(+) => 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O


name: UDP-alpha-D-glucuronate(out) + UMP(in) => UDP-alpha-D-glucuronate(in) + UMP(out)


name: NAD(+) + pyridoxal => 4-pyridoxolactone + H(+) + NADH


name: USP8 deubiquitinates LRIG1 (Rattus norvegicus)


name: (2E,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H2O => (3R)-hydroxy-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA


name: Interaction of integrin alphaIIb beta3 with Fibrinogen (Drosophila melanogaster)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Homo sapiens)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Rattus norvegicus)


name: TP53BP1 associates with H4K20Me2 at DNA DSBs (Canis familiaris)


name: (3R)-[(10S)-11-epoxyfarnesyl]-2,3,5-trimethyl-6-oxido-4-oxocyclohexa-1,5-diene-1-carboxylate + H(+) = asnovolin H


name: JMJD6 demethylates MeR3-histone H3 (Homo sapiens)


name: Release of platelet cytosolic components (Plasmodium falciparum)


name: H2O + long chain 1,2-diacyl-3-O-beta-D-galactosyl-sn-glycerol = a fatty acid + H(+) + long chain acyl-3-O-beta-D-galactosyl-sn-glycerol


name: TFIIS-mediated recovery of elongation from arrest (Homo sapiens)


name: ATG12:ATG7:CysO572-ATG7 binds ATG10 (Canis familiaris)


name: UNC119B binds myristoylated proteins (Danio rerio)


name: FGF2:TGFBR3 binding to GIPC1 (Gallus gallus)


name: Formation of the MCC complex (Saccharomyces cerevisiae)


name: hexadecanoate + sphing-4-enine => H2O + N-hexadecanoylsphing-4-enine


name: CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin (Sus scrofa)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Homo sapiens)


name: 13-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 13-hydroxy-octadecanoate + H(+)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Xenopus tropicalis)


name: SUMOylation of TOP2B with SUMO1 (Xenopus tropicalis)


name: L-Glutamine transport into neurons (Gallus gallus)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Sus scrofa)


name: SLC4A4 cotransports Na+ with 3HCO3- (Rattus norvegicus)


name: UDP(in) + UDP-alpha-D-glucuronate(out) = UDP(out) + UDP-alpha-D-glucuronate(in)


name: (2Z,6Z)-farnesyl diphosphate + 2 diphosphate => dimethylallyl diphosphate + 2 isopentenyl diphosphate


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Homo sapiens)


name: 1-decanoyl-sn-glycero-3-phosphocholine + H2O = 1-decanoyl-sn-glycero-3-phosphate + choline + H(+)


name: Prokineticin receptors bind prokineticin (Canis familiaris)


name: 2-oxo-dATP + H2O <=> 2-oxo-dAMP + diphosphate + H(+)


name: 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] + 6 CO2 + 7 CoA => acetyl-CoA + 6 H(+) + holo-[ACP] + 6 malonyl-CoA


name: 5 (S)-methylmalonyl-CoA + 11 H(+) + malonyl-CoA + 5 NADPH = 10-deoxymethynolide + 6 CO2 + 6 CoA + 2 H2O + 5 NADP(+)


name: ABC-type phosphonate transporter activity


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Sus scrofa)


name: dodecanoyl-CoA + glycine = CoA + H(+) + N-dodecanoylglycine


name: Recruitment of Dna2 endonuclease (Canis familiaris)


name: H(+) + H2O2 + harderoheme III = CO2 + 2 H2O + heme b


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H2O <=> C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Gallus gallus)


name: 15-oxoprostaglandin E1 + H(+) + NADPH => 13,14-dihydro-15-oxo-prostaglandin E1 + NADP(+)


name: N-acetylindoxyl + O2 => H2O + N-acetylisatin


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Caenorhabditis elegans)


name: SLC6A18 transports Gly from extracellular region to cytosol (Plasmodium falciparum)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Danio rerio)


name: P2X1-mediated entry of Ca++ from plasma (Dictyostelium discoideum)


name: Myristoylated NPHP3 translocates into the ciliary membrane (Canis familiaris)


name: (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) <=> 2,3-dihydroxy-p-cumate + H(+) + NADH


name: PEX19 binds class I peroxisomal membrane proteins (Mus musculus)


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Caenorhabditis elegans)


name: REV1 inserts dCMP opposite to AP sites in DNA (Gallus gallus)


name: PTP1B binds the GH receptor complex (Rattus norvegicus)


name: 3-sulfanylpentan-1-ol-L-cysteine + H2O <=> 3-sulfanyl-1-pentanol + NH4(+) + pyruvate


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: adenosine 2'-phosphate + H2O <=> adenosine + phosphate


name: Formation of dehydro-lysinonorleucine cross-links (Danio rerio)


name: (3R)-3-hydroxydodecanoyl-CoA + NAD(+) => 3-oxododecanoyl-CoA + H(+) + NADH


name: DELE1(143-515) binds EIF2AK1 (HRI) (Xenopus tropicalis)


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Canis familiaris)


name: Dissociation of L13a from the 60s ribosomal subunit (Mus musculus)


name: Autophosphorylation of SRC (Rattus norvegicus)


name: SIRT3 deacetylates Ac-K272,K290-FOXO3 (Bos taurus)


name: 2 L-ascorbate + N-octanoylglycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-octanoyl-(2S)-hydroxyglycine


name: ERCC8 (CSA) binds stalled RNA Pol II (Caenorhabditis elegans)


name: asc-C13-CoA + O2 = asc-DeltaC13-CoA + H2O2


name: EGFR activates PLC-gamma1 by phosphorylation (Sus scrofa)


name: a D-hexose 6-phosphate + ADP + H(+) => a D-hexose + ATP


name: Interaction of other adapter proteins with p-KIT (Sus scrofa)


name: TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9 (Homo sapiens)


name: SDH complex dehydrogenates succinate (Canis familiaris)


name: MAOB:FAD oxidatively deaminates TYR (Sus scrofa)


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Gallus gallus)


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Saccharomyces cerevisiae)


name: MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB (Homo sapiens)


name: Cleavage of uracil by UNG glycosylase (Sus scrofa)


name: p-Y705, p-S727 STAT3 dimer translocates to the nucleus (Rattus norvegicus)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Gallus gallus)


name: Association of procollagen type VIII (Homo sapiens)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Gallus gallus)


name: (-)-cyatha-3,12-diene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Sus scrofa)


name: H(+) + NADPH + scyllo-inosose => NADP(+) + scyllo-inositol


name: 3alpha-hydroxyglycyrrhetinate + NADP(+) => 3-oxoglycyrrhetinate + H(+) + NADPH


name: Ubiquitinated geminin is degraded by the proteasome (Mus musculus)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] => 6beta-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of the inner ring of the 20S immunoproteasome core particle (Drosophila melanogaster)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Schizosaccharomyces pombe)


name: acetoacetyl-CoA + H(+) + NADH => 3-hydroxybutanoyl-CoA + NAD(+)


name: diphosphate + fumitremorgin B => 12alpha,13alpha-dihydroxyfumitremorgin C + dimethylallyl diphosphate


name: ADP + glutathione(out) + glycocholate(out) + H(+) + phosphate => ATP + glutathione(in) + glycocholate(in) + H2O


name: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol (Homo sapiens)


name: Necl-1:Nectin 3 trans heterodimer interaction (Mus musculus)


name: 2,4,6-trinitrotoluene + NADPH <=> 4-methyl-1,3,5-trinitrocyclohexa-2,4-dien-1-ide + NADP(+)


name: IL10 negatively regulates extracellular inflammatory mediators (Homo sapiens)


name: 2-oxoglutarate + L-homoarginine + O2 <=> 6-hydroxy-L-homoarginine + CO2 + succinate


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Mus musculus)


name: mito-STARD7 transports Q10 to outer mitochondrial membrane (Homo sapiens)


name: SLC19A2/3 transport extracellular THMN to cytosol (Canis familiaris)


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine => diphthine-[translation elongation factor 2] + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: Sulfido conjugates translocate from cytosol to extracellular region (Homo sapiens)


name: (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine => 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoserine + CoA


name: Movement of clathrin coated vesicles into early endosome (Danio rerio)


name: KCNH2:KCNE transport K+ from cytosol to extracellular region (Gallus gallus)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Gallus gallus)


name: a 1,3-diacylglycerol + CoA => a 1-acylglycerol + an acyl-CoA


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Drosophila melanogaster)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Rattus norvegicus)


name: D-erythrose 4-phosphate + H2O = D-erythrose + phosphate


name: MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Homo sapiens)


name: RUNX1 binds to TNFRSF18 (GITR) gene promoter and intron 1 (Homo sapiens)


name: RP2 binds ARL3:GTP:UNC119B (Canis familiaris)


name: Defective GNE does not phosphorylate ManNAc to ManNAc-6-P (Homo sapiens)


name: GRK2 sequesters activated Gq (Caenorhabditis elegans)


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Mus musculus)


name: Ubiquitinated AXIN is degraded by the proteasome (Rattus norvegicus)


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Mus musculus)


name: L-aspartate + NAD(+) = H(+) + iminosuccinate + NADH


name: enoyl-[acyl-carrier-protein] reductase activity (NAD(P)H)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H(+) => a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate


name: PIP3 recruits PDK1 and AKT to the membrane (Saccharomyces cerevisiae)


name: 3-methoxybenzaldehyde + hydrogen cyanide => (2S)-2-hydroxy-2-(3-methoxyphenyl)acetonitrile


name: 6-O-methyl-N-deacetylipecoside + H2O => 6-O-methyl-N-deacetylipecoside aglycone + D-glucose


name: PEX5L:PEX7:Cargo binds PEX13:PEX14:PEX2:PEX10:PEX12 (Docking and Translocation Module) (Homo sapiens)


name: PEX19:class I PMP binds PEX3 (Saccharomyces cerevisiae)


name: (3R)-3-isocyanylbutanoate + ATP + H(+) = (3R)-3-isocyanylbutanoyl-AMP + diphosphate


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Drosophila melanogaster)


name: (1R,2S,4R)-neodihydrocarveol + NAD(+) = (1R,4R)-dihydrocarvone + H(+) + NADH


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Bos taurus)


name: 4 (R)-2-hydroxy-3-methylbutyrate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine => 8 AMP + bassianolide + 8 diphosphate + 8 H(+) + 4 S-adenosyl-L-homocysteine


name: H2O + N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Aquaporins passively transport urea into cells (Rattus norvegicus)


name: (+)-7-isojasmonate + ATP + L-isoleucine => AMP + diphosphate + H(+) + L-isoleucine-(+)-7-isojasmonate


name: uridine(2457) in 23S rRNA <=> pseudouridine(2457) in 23S rRNA


name: Expression of Ras-related protein Ral-A (Homo sapiens)


name: c-FOS activation by phospho ERK1/2 (Gallus gallus)


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Canis familiaris)


name: Activated protein C is released from PROCR (Gallus gallus)


name: SIRT1 deacetylates HINT1 dimer (Caenorhabditis elegans)


name: delta-tocopherol + S-adenosyl-L-methionine <=> beta-tocopherol + H(+) + S-adenosyl-L-homocysteine


name: 10-deoxymethymycin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + novamethymycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Sus scrofa)


name: 8-oxo-dATP + H2O => 8-oxo-dAMP + diphosphate + H(+)


name: (S)-homoeriodictyol + H(+) + S-adenosyl-L-homocysteine => (S)-eriodictyol + S-adenosyl-L-methionine


name: ESR1 binds ESR1 antagonists (Bos taurus)


name: SDHAF4 binds to FAD-SDHA (Schizosaccharomyces pombe)


name: OSCAR binds collagen and SP-D (Mus musculus)


name: p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Danio rerio)


name: (R)-mandelonitrile = benzaldehyde + hydrogen cyanide


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-alpha-D-galactose = H(+) + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP


name: RHOA binds effectors at the ER membrane (Mus musculus)


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin] => 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 oxidized 2[4Fe-4S]-[ferredoxin]


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Bos taurus)


name: chloride(out) + nitrate(in) <=> chloride(in) + nitrate(out)


name: holo-[(phenol)carboxyphthiodiolenone synthase] + icosanoyl-AMP <=> AMP + H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: ADP + D-galactose(in) + H(+) + phosphate => ATP + D-galactose(out) + H2O


name: 7alpha-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Homo sapiens)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Caenorhabditis elegans)


name: 14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Drosophila melanogaster)


name: PARG dePARylates PARP1,PARP2 (Mus musculus)


name: 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + CTP => CMP-8-amino-3,8-dideoxy-alpha-D-manno-oct-2-ulosonate + diphosphate


name: a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + N-acetyl-alpha-D-galactosamine => a neolactoside IV(3)-alpha-GalNAc,IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O


name: chloride(out) + D-tryptophan(out) + 2 Na(+)(out) <=> chloride(in) + D-tryptophan(in) + 2 Na(+)(in)


name: CARD9 binds RIP2 (and NOD2) (Homo sapiens)


name: 17-beta-hydroxysteroid dehydrogenase (NADP+) activity


name: a 17beta-hydroxy steroid + NADP(+) = a 17-oxo steroid + H(+) + NADPH


name: DHODH:FMN binds DHODH inhibitors (Mus musculus)


name: USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 (Caenorhabditis elegans)


name: Association of Emi1 with Cdc20 (Mus musculus)


name: Formation of AT-AC B Complex (Canis familiaris)


name: 2-oxoglutarate + O2 + taurine => aminoacetaldehyde + CO2 + H(+) + succinate + sulfite


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Mus musculus)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Drosophila melanogaster)


name: PCSK9 binds PCSK9 inhibitors (Mus musculus)


name: SARDH:FAD oxidatively demethylates SARC to Gly (Homo sapiens)


name: (3R)-3-isocyanylbutanoate + ATP + H(+) <=> (3R)-3-isocyanylbutanoyl-AMP + diphosphate


name: (+)-5-epi-aristolochene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => capsidiol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Dictyostelium discoideum)


name: N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal) (Homo sapiens)


name: USP13 and OTUD3 deubiquitinate PTEN (Homo sapiens)


name: ATP + H2O + prostaglandin E1(in) = ADP + H(+) + phosphate + prostaglandin E1(out)


name: CDP(out) + CDP-L-ribitol(in) <=> CDP(in) + CDP-L-ribitol(out)


name: (1R,2R,3R)-prephytoene diphosphate + H(+) + NADH <=> all-trans-lycopaoctaene + diphosphate + NAD(+)


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate <=> etheroleate + H2O


name: 3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Gallus gallus)


name: TRAF6 binds MALT1 oligomers (Canis familiaris)


name: beta-lactose + O2 = H2O2 + lactobiono-1,5-lactone


name: a dicarboxylate(in) + urate(out) => a dicarboxylate(out) + urate(in)


name: p-PKR dimer phosphorylates MKK6 (Gallus gallus)


name: 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + NH4(+) => 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + H(+) + H2O


name: p-STAT1:p-STAT4 translocates to the nucleus (Homo sapiens)


name: AKT interacts and phosphorylates Cot (Saccharomyces cerevisiae)


name: a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-homocysteine


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Dictyostelium discoideum)


name: Formation of Okazaki fragments (Bos taurus)


name: GLI proteins bind SUFU (Drosophila melanogaster)


name: Phosphorylation (Ser5) of RNA pol II CTD (Mus musculus)


name: 2-amino-3-carboxymuconate semialdehyde => 2-aminomuconate semialdehyde + CO2 (Homo sapiens)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Mus musculus)


name: Caspase-mediated cleavage of Desmoglein 3 (Sus scrofa)


name: [(1->2)-beta-D-glucosyl](n)(in) + ATP + H2O => [(1->2)-beta-D-glucosyl](n)(out) + ADP + H(+) + phosphate


name: amidinoproclavaminate + H2O = proclavaminate + urea


name: 5-(9Z-hexadecenoyloxy)-octadecanoate + H2O = (9Z)-hexadecenoate + 5-hydroxy-octadecanoate + H(+)


name: (4R)-ipsdienol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => beta-myrcene + O2 + reduced [NADPH--hemoprotein reductase]


name: "Activator" RAF:YWHAB dimer binds RAS:GTP (Sus scrofa)


name: a (3E)-enoyl-CoA => a 4-saturated (2E)-enoyl-CoA


name: (9Z)-octadecenoyl-CoA + 1-dodecanoylglycerol = 1-dodecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: (6Z,9Z,12Z)-octadecatrienoate + H2O <=> (10S)-hydroxy-(6Z,12Z)-octadecadienoate


name: 2 a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol <=> a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a 1,2-diacyl-sn-glycerol


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Plasmodium falciparum)


name: Activation of highly calcium permeable nicotinic acetylcholine receptors (Drosophila melanogaster)


name: p300 acetylates RELA subunit (Mus musculus)


name: Activated FGFR3 phosphorylates PPTN11 (Drosophila melanogaster)


name: SUMOylation of TDG with SUMO2,3 (Drosophila melanogaster)


name: 4-hydroxy-L-proline(out) + H(+)(out) => 4-hydroxy-L-proline(in) + H(+)(in)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Danio rerio)


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Mus musculus)


name: a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] => a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]


name: FDPS dimer transfers IPPP to DMAPP (Mus musculus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O => 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-xylose => an anthocyanidin 3-O-beta-D-sambubioside + 2 H(+) + UDP


name: solute:inorganic anion antiporter activity


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-Glc + GDP + H(+) => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Danio rerio)


name: USP21 deubiquitinates GATA3,IL33 (Canis familiaris)


name: SLC6A6-mediated uptake of taurine and beta-alanine (Danio rerio)


name: SUMOylation of TOP2B with SUMO1 (Bos taurus)


name: Squalene is oxidized to its epoxide (Sus scrofa)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Homo sapiens)


name: Calmodulin dissociates KRAS4B from the plasma membrane (Canis familiaris)


name: Full-length GD is cleaved by an unknown protease (Drosophila melanogaster)


name: 3 H(+) + holo-[2-methylbutanoate polyketide synthase] + 2 malonyl-CoA + 2 NADPH + S-adenosyl-L-methionine => (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CO2 + 2 CoA + H2O + 2 NADP(+) + S-adenosyl-L-homocysteine


name: O2 + quercetin + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + myricetin + oxidized [NADPH--hemoprotein reductase]


name: FOXG1 binds FOXO:SMAD complexes (Gallus gallus)


name: fusidate(in) + H(+)(out) = fusidate(out) + H(+)(in)


name: PNP trimer transforms RBV to T-CONH2 (Bos taurus)


name: GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-(9Z-octadecenoyl)-glycerol


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Canis familiaris)


name: 4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine => 4-(3-methylbut-2-enyl)-L-abrine + H(+) + S-adenosyl-L-homocysteine


name: cyathadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => erinacol + O2 + reduced [NADPH--hemoprotein reductase]


name: glycyl-5'-AMP + holo-[peptidyl-carrier protein] => AMP + glycyl-[peptidyl-carrier protein] + H(+)


name: NADP(+) + sphinganine = 3-oxosphinganine + H(+) + NADPH


name: beta-D-Gal-(1<->1')-Cer + CMP-N-acetyl-beta-neuraminate <=> CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-ceramide


name: (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Mus musculus)


name: (S)-3-hydroxybutanoate(out) + H(+)(out) <=> (S)-3-hydroxybutanoate(in) + H(+)(in)


name: (6Z,9Z,12Z)-octadecatrienoate + O2 = 10R-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate


name: an omega-hydroxy fatty acid + O2 + reduced [NADPH--hemoprotein reductase] <=> an omega-oxo fatty acid + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: EGFRvIII mutant binds chaperone proteins HSP90 and CDC37 (Homo sapiens)


name: A + O2 + reduced [NADPH--hemoprotein reductase] + tetrahydroalstonine => AH2 + alstonine + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + L-lysyl(27)-[histone H3] + 2 succinate


name: 2-demethylmenaquinol-6 + S-adenosyl-L-methionine = H(+) + menaquinol-6 + S-adenosyl-L-homocysteine


name: [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + [eIF5A protein]-L-lysine => [deoxyhypusine synthase]-L-lysine + [eIF5A protein]-N-(4-aminobutylidene)-L-lysine


name: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine <=> H(+) + menaquinol-7 + S-adenosyl-L-homocysteine


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Xenopus tropicalis)


name: G-proteins dissociate from plasma-membrane estrogen receptors (Homo sapiens)


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Canis familiaris)


name: 2-methyl-(2E)-pentadecenoyl-CoA + H2O2 => (2S)-methylpentadecanoyl-CoA + O2


name: glyoxylate + L-glutamate => 2-oxoglutarate + glycine


name: hexadecanoyl-AMP + holo-[ACP] <=> AMP + H(+) + hexadecanoyl-[ACP]


name: A + Co-precorrin-4 + S-adenosyl-L-homocysteine => AH2 + Co(II)-factor III + S-adenosyl-L-methionine


name: an adenosine in mRNA + S-adenosyl-L-methionine = an N(1)-methyladenosine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: SEMA4A binds to PLXND1 (Rattus norvegicus)


name: MetAsp transforms to L-Asp,isoAsp (Homo sapiens)


name: 5-phospho-D-xylonate + H(+) => D-xylono-1,4-lactone 5-phosphate + H2O


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Rattus norvegicus)


name: Thyrotropin is a heterodimer (Xenopus tropicalis)


name: 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: 2-demethylmenaquinol-9 + S-adenosyl-L-methionine <=> H(+) + menaquinol-9 + S-adenosyl-L-homocysteine


name: Fc gamma receptors interact with antigen-bound IgG (Mus musculus)


name: tetX LC cleaves target cell VAMP2 (Homo sapiens)


name: p-Y705-STAT3,p-Y641-STAT6 dissociate (Gallus gallus)


name: Activation of ATP sensitive Potassium channels in muscle cells (Canis familiaris)


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Rattus norvegicus)


name: glycodeoxycholate(in) + 2 Na(+)(in) => glycodeoxycholate(out) + 2 Na(+)(out)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + isonocardicin C + S-methyl-5'-thioadenosine => nocardicin G + S-adenosyl-L-methionine


name: propane-1,3-diamine + pyruvate = 3-aminopropanal + L-alanine


name: H2O + N(5)-acyl-L-ornithine ester = an alcohol + H(+) + N(5)-acyl-L-ornithine


name: A + peniprequinolone => AH2 + yaequinolone E


name: mTORC1 phosphorylates AKT1S1 (Bos taurus)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Drosophila melanogaster)


name: H2O + N-(4-aminobutylpyrrolinium) ion + O2 = H2O2 + N-(4-oxobutylpyrrolinium) ion + NH4(+)


name: digoxigenin + 2 Fe(II)-[cytochrome c] + 3 H(+) => dihydrodigoxigenin + 2 Fe(III)-[cytochrome c]


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Xenopus tropicalis)


name: H(+) + NADPH + nitrobenzene => H2O + NADP(+) + nitrosobenzene


name: a (2E)-enoyl fatty acid + ATP + holo-[ACP] = a (2E)-enoyl-[ACP] + AMP + diphosphate


name: a 2'-deoxyribonucleoside 5'-phosphate + H(+) + phosphate => a 2'-deoxyribonucleoside 5'-diphosphate + H2O


name: MIB2 binds CFLAR (Drosophila melanogaster)


name: a 1,3-diacylglycerol + H2O <=> a 1-acylglycerol + a fatty acid + H(+)


name: N-formiminoglutamate + tetrahydrofolate => glutamate + 5-formiminotetrahydrofolate (Canis familiaris)


name: CYP3A4,5 hydroxylates AFB1 to AFQ1 (Sus scrofa)


name: decanoate + H(+) + holo-[ACP] => decanoyl-[ACP] + H2O


name: asperterpenoid A + 5 H(+) + 5 H2O + 4 oxidized [NADPH--hemoprotein reductase] => 4 O2 + preasperterpenoid A + 4 reduced [NADPH--hemoprotein reductase]


name: SULTs transfer (SO4)2- group to PREG (Xenopus tropicalis)


name: Relocalization of nuclearly localized Cyclin D1 to the cytoplasm (Canis familiaris)


name: 6beta-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => estrone + O2 + reduced [NADPH--hemoprotein reductase]


name: a beta-D-galactoside + acetyl-CoA => a 6-acetyl-beta-D-galactoside + CoA


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Xenopus tropicalis)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Bos taurus)


name: dimethylallyl diphosphate + H2O + yaequinolone E <=> [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate


name: indole acetic acid carboxyl methyltransferase activity


name: AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)


name: 11-O-acetylcyathatriol + UDP-alpha-D-xylose => erinacine Q + H(+) + UDP


name: Thr-180 of ULK1 is phosphorylated (Drosophila melanogaster)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Gallus gallus)


name: 4 norrubrofusarin + O2 = 2 H2O + 2 ustilaginoidin A


name: dihydroxyacetone phosphate + hexadecanoyl-CoA => 1-hexadecanoylglycerone 3-phosphate + CoA


name: diphthine methyl ester-[translation elongation factor 2] + H2O = diphthine-[translation elongation factor 2] + H(+) + methanol


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Rattus norvegicus)


name: factor IXa associates with cell membrane (Homo sapiens)


name: uridine(27/28) in mitochondrial tRNA = pseudouridine(27/28) in mitochondrial tRNA


name: "mitochondrial tRNA pseudouridine(27/28) synthase"


name: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an (11E)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Sus scrofa)


name: 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Danio rerio)


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Homo sapiens)


name: NEU2 hydrolyzes Neu5Ac from glycoconjugates (Gallus gallus)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Gallus gallus)


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Homo sapiens)


name: mature RAS proteins translocate to plasma membrane (Drosophila melanogaster)


name: "Thioether and trialkylsulfonium hydrolases"


name: Glucagon-like Peptide 1 is secreted from intestinal L cells (Xenopus tropicalis)


name: DNA nucleases bind monoubiquitinated ID2 complex (Rattus norvegicus)


name: a 2-acylglycerol + an acyl-CoA = a 1,2-diacyl-sn-glycerol + CoA


name: Phosphorylation and release of IRF3/IRF7 (Homo sapiens)


name: (25R)-3beta,26-dihydroxycholest-5-en-7-one + H2O + 2 oxidized [adrenodoxin] => 7-oxocholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: ATP + folate(in) + H2O => ADP + folate(out) + H(+) + phosphate


name: AMP + H2O => IMP + NH4+ (AMPD) (Schizosaccharomyces pombe)


name: 2 H(+) + H2O + L-citrulline => CO2 + L-ornithine + NH4(+)


name: (d)AMP + ATP <=> (d)ADP + ADP (AK1) (Caenorhabditis elegans)


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)


name: (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O = 2-dehydro-3-deoxy-D-gluconate + NH4(+)


name: SLC6A18 transports Gly from extracellular region to cytosol (Gallus gallus)


name: (R,S)-butane-2,3-diol + NAD(+) => (R)-acetoin + H(+) + NADH


name: 5 H(+) + 3 O2 + obtusifoliol + 6 reduced [2Fe-2S]-[ferredoxin] = 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: PVALB gene expression is repressed by MECP2 (Homo sapiens)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Mus musculus)


name: HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12) (Drosophila melanogaster)


name: (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H(+) + NADPH <=> (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: A + cannabigerolate = AH2 + cannabichromenate


name: 3-methylundecanoate + ATP + CoA = 3-methylundecanoyl-CoA + AMP + diphosphate


name: PSMD9 binds PSMC3:PSMC6 (Saccharomyces cerevisiae)


name: Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Mus musculus)


name: Endonucleolytic RISC hydrolyzes target RNAs (Xenopus tropicalis)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Sus scrofa)


name: PPO oxidises PPGEN9 to PRIN9 (Dictyostelium discoideum)


name: 7,8-dihydrofolate + dTMP => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP


name: STON2 binds SYT proteins (Rattus norvegicus)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Gallus gallus)


name: (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O <=> (11R,12R)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: FAAH hydrolyses AEA to AA and ETA (Xenopus tropicalis)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Mus musculus)


name: NMRK2 phosphorylates NR to yield NMN (Mus musculus)


name: 6-hydroxypseudooxynicotine => 6-hydroxy-N-methylmyosmine + H2O


name: [Pyr1]apelin-12 + L-phenylalanine => [Pyr1]apelin-13 + H2O


name: SARS-CoV-1 9b recruits ITCH to MAVS  (Homo sapiens)


name: adenosine 5'-phosphosulfate + ATP <=> 3'-phosphoadenylyl sulfate + ADP + H(+)


name: 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + 2 GDP + 2 H(+) => bis(myo-inositol) 1,3'-phosphate + 2 GDP-alpha-D-mannose


name: MTMR4 dephosphorylates SMAD2/3 (Homo sapiens)


name: D-tryptophan + O2 => N-formyl-D-kynurenine


name: PTGS2 dimer binds PTGS2 inhibitors (Homo sapiens)


name: (2S)-3-sulfolactaldehyde + H2O + NADP(+) <=> (2S)-3-sulfolactate + 2 H(+) + NADPH


name: TNRC6A binds AGO2:miRNA (Canis familiaris)


name: SMURF2 binds SMAD3 phosphorylated in the linker region (Mus musculus)


name: 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + zealexin A1 => (S)-beta-macrocarpene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: (3S)-hydroxytetracosanoyl-CoA + NAD(+) <=> 3-oxotetracosanoyl-CoA + H(+) + NADH


name: 2,3-epoxyphylloquinone + 4-carboxy-L-glutamyl-[protein] + H(+) + H2O = CO2 + L-glutamyl-[protein] + O2 + phylloquinol


name: AKT phosphorylates MDM2 (Rattus norvegicus)


name: a 3beta-hydroxy-4beta-formyl-4alpha-methylsteroid + 2 H2O + NAD(+) => a 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + H(+) + NADH + O2


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Canis familiaris)


name: H2O + ipecoside = D-glucose + ipecoside aglycone


name: DRD2 antagonist drugs bind to DRD2 (Homo sapiens)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Mus musculus)


name: The keratan chain can be capped by N-acetylneuraminic acid (Mus musculus)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Bos taurus)


name: TP receptor can bind thromboxane (Canis familiaris)


name: PHF8 demethylates MeK21-histone H4 (Caenorhabditis elegans)


name: VAV exchanges GTP for GDP on RAC1, activating it (Bos taurus)


name: Association of procollagen type XI (Canis familiaris)


name: MAF1 translocates to the nucleus (Dictyostelium discoideum)


name: D-threonine + H2O + O2 <=> (S)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Canis familiaris)


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Dictyostelium discoideum)


name: 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-methionine = 5-hydroxy-3,7,3',4'-tetramethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: Trafficking of nonameric complex in the endocytic pathway (Bos taurus)


name: ribitol-5-phosphate 2-dehydrogenase [(NAD(P)+] activity


name: (1S)-3-methyl-cyclohexylamine + H2O + NAD(+) <=> 3-methylcyclohexanone + H(+) + NADH + NH4(+)


name: a carboxylic ester + H2O => a carboxylate + an alcohol + H(+)


name: ALK autophosphorylation  (Canis familiaris)


name: 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate = dihydroxyacetone phosphate + L-aspartate 4-semialdehyde


name: VAV2 is a GEF for Rho/Rac family kinases (Caenorhabditis elegans)


name: 4-methylene-L-glutamine + H2O => 4-methylene-L-glutamate + NH4(+)


name: IFNG dimer binds IFNG inhibitors (Rattus norvegicus)


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Plasmodium falciparum)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Saccharomyces cerevisiae)


name: gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity


name: PAK1 phosphorylates FLNA (Xenopus tropicalis)


name: (R)-4-phosphopantoate + ATP + beta-alanine => (R)-4'-phosphopantothenate + AMP + diphosphate + H(+)


name: PDGF dimer binds two receptors simultaneously (Sus scrofa)


name: 4 AH2 + all-trans-lycopene => 15-cis-phytoene + 4 A


name: FLT3LG dimer binds FLT3 (Canis familiaris)


name: erythromycin C + H2O + NADP(+) => erythromycin D + H(+) + NADPH + O2


name: H(+) + keto-D-tagaturonate + NADH => D-mannonate + NAD(+)


name: dTDP-beta-L-rhamnose + N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol <=> alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + dTDP + H(+)


name: ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Drosophila melanogaster)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Gallus gallus)


name: USP5 cleaves polyubiquitin (Gallus gallus)


name: 3-oxopristanoyl-CoA + CoA => 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Mus musculus)


name: (2R)-3-sulfolactate => H(+) + pyruvate + sulfite


name: L-gulonate + NAD(+) => H(+) + keto-D-fructuronate + NADH


name: Serotonin loaded synaptic vesicle docking and priming (Mus musculus)


name: (2S,3R)-3-geranyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate => (2E)-geranyl diphosphate + L-tryptophyl-[protein]


name: Formation of C-strand Okazaki fragments (Homo sapiens)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + ATP <=> a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + AMP + diphosphate


name: (S)-6-hydroxynicotine + AH2 => (S)-nicotine + A + H2O


name: TRAF6 is K63 poly-ubiquitinated (Rattus norvegicus)


name: Formation of the PA28-alpha-beta-20S proteasome (Drosophila melanogaster)


name: SIRT4 transfers ADPRib to GLUD (Bos taurus)


name: glyoxylate + NADPH + H+ => glycolate + NADP+ (Canis familiaris)


name: 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine => 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: PPARG binds PPARG agonists (Canis familiaris)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Schizosaccharomyces pombe)


name: TP53 family members stimulate CASP1 expression (Homo sapiens)


name: L-aspartate(out) + L-leucine(in) => L-aspartate(in) + L-leucine(out)


name: (R)-pantetheine + ATP = (R)-4'-phosphopantetheine + ADP + H(+)


name: (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O => 2-oxopent-4-enoate + formate + H(+)


name: a ganglioside GD2 (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD2(d18:1(4E)) + CoA


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Homo sapiens)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Dictyostelium discoideum)


name: GDP-alpha-D-mannose + N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate => alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: H(+) + NADPH + neopinone => NADP(+) + neopine


name: (E)-coniferaldehyde + H2O + NAD(+) = (E)-ferulate + 2 H(+) + NADH


name: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => a Delta(14) steroid + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: a 3-oxoacyl-[ACP] + H(+) + NADPH => a (3R)-hydroxyacyl-[ACP] + NADP(+)


name: Thrombin proteolyzes IGF:IGFBP3:ALS (Rattus norvegicus)


name: RHOD translocates to the mitochondrial outer membrane (Schizosaccharomyces pombe)


name: [(1->4)-beta-D-glucosyl](n) + phosphate => [(1->4)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: RHOA:GTP:RTKN binds TAX1BP3 (Rattus norvegicus)


name: docosanoyl-CoA + H(+) + malonyl-CoA => 3-oxotetracosanoyl-CoA + CO2 + CoA


name: [thioredoxin]-dithiol + a ribonucleoside 5'-triphosphate => [thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-triphosphate + H2O


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Xenopus tropicalis)


name: H2O + N,1-dihexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => (9Z,12Z)-octadecadienoate + H(+) + N,1-dihexadecanoyl-sn-glycero-3-phosphoethanolamine


name: PINK1 phosphorylates Ub on MOM proteins (Homo sapiens)


name: FKBP5 gene expression is inhibited by MECP2 (Homo sapiens)


name: Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Caenorhabditis elegans)


name: WIPI2 binds ATG12:ATG5:ATG16L (Dictyostelium discoideum)


name: Rsu-1 interacts with Pinch1 (Mus musculus)


name: RNF20:RNF40 monoubiquitinates Histone H2B (Homo sapiens)


name: (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) (Mus musculus)


name: 2-oxoglutarate + L-isoleucine + O2 => 3(1)-hydroxy-L-isoleucine + CO2 + succinate


name: UDP-N-acetyl-alpha-D-glucosamine <=> H2O + UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose


name: N-formyl-D-kynurenine => D-tryptophan + O2


name: Activated P2Y purinoceptor 12 binds G-protein Gi (Bos taurus)


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Sus scrofa)


name: 1-O-alkyl-2-acyl-sn-glycerol + a fatty acid + H(+) => 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O


name: 1-nonadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: TRADD:TRAF2:RIP1 complex dissociates from the TNF-α:TNF-R1 complex (Rattus norvegicus)


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Bos taurus)


name: 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase]


name: L-aspartate + NADPH + O2 <=> H2O + N-hydroxy-L-aspartate + NADP(+)


name: ISGylation of protein phosphatase 1 beta (PP2CB) (Caenorhabditis elegans)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H(+)


name: p-STAT1 dimer binds KPNA1 (Rattus norvegicus)


name: oxidoreductase activity, acting on reduced flavodoxin as donor


name: RHOQ binds effectors at the plasma membrane (Mus musculus)


name: a gentamycin + GTP = a gentamycin 2''-phosphate + GDP + H(+)


name: ATP + H2O + L-kynurenine(out) <=> ADP + H(+) + L-kynurenine(in) + phosphate


name: NADH + nitroglycerin <=> 1,3-dinitroglycerol + NAD(+) + nitrite


name: PKR binds activating host RNA (Xenopus tropicalis)


name: PCSK9 binds PCSK9 inhibitors (Homo sapiens)


name: GDP-alpha-D-rhamnose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Xenopus tropicalis)


name: ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Drosophila melanogaster)


name: Defective HYAL1 does not hydrolyse (HA)50 (Homo sapiens)


name: ATP + H(+) + L-arginine <=> diphosphate + L-arginyl-AMP