name: NAD(+) <=> ADP-1-deoxy-1,O(4)-didehydro-D-ribose + nicotinamide


name: (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2 => (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2


name: n chloride(in) + urate(out) => n chloride(out) + urate(in)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Drosophila melanogaster)


name: ATP + L-isoleucine + tRNA(Ile) => AMP + diphosphate + L-isoleucyl-tRNA(Ile)


name: NDUF subunits bind to form the FP subcomplex (Rattus norvegicus)


name: AKT phosphorylates MKRN1 (Dictyostelium discoideum)


name: IGFBP1 binds IGF forming IGF:IGFBP1 (Bos taurus)


name: Dimerization of LIMK1 by Hsp90 (Sus scrofa)


name: Cleavage of ethenoadenine by MPG glycosylase (Plasmodium falciparum)


name: atRAL is reduced to atROL (Mus musculus)


name: CO2 + H(+) + propanoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] => 2-oxobutanoate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Saccharomyces cerevisiae)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Rattus norvegicus)


name: 12,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 12-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: IDH3 complex decarboxylates isocitrate (Mus musculus)


name: CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Rattus norvegicus)


name: Release of the SLBP independent Histone mRNA from the NPC (Sus scrofa)


name: ADAMTS13 cleaves VWF multimer (Sus scrofa)


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H2O => L-seryl-[protein] + N-acetyl-D-galactosamine


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Mus musculus)


name: RUNX3 binds the NOTCH1 coactivator complex (Canis familiaris)


name: trans-Golgi Network Vesicle Scission (Caenorhabditis elegans)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Gallus gallus)


name: H2O + isochorismate => (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate


name: 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + ATP + L-cysteine <=> 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + H(+)


name: CO2 + N,N-dimethyl-cadaverine => H(+) + N(6),N(6)-dimethyl-L-lysine


name: MCM4, MCM6 and MCM7 form a heterotrimer (Schizosaccharomyces pombe)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Homo sapiens)


name: 3,5,7,9,11-pentaoxododecanoyl-[ACP] => 6,8-dihydroxy-3-(2-oxopropyl)-isocoumarin + H2O + holo-[ACP]


name: all-trans-4,4'-diaponeurosporene + 3 FADH2 => 15-cis-4,4'-diapophytoene + 3 FAD + 3 H(+)


name: Transport (influx) of bile salts and acids by OATP-A (Drosophila melanogaster)


name: B3GAT dimers transfer GlcA to tetrasaccharide linker (Danio rerio)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Bos taurus)


name: Melanocortin receptors bind melanocortins (Danio rerio)


name: glutaryl-CoA + L-lysyl-[protein] => CoA + H(+) + N(6)-glutaryl-L-lysyl-[protein]


name: BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Mus musculus)


name: AKT can phosphorylate NR4A1 (NUR77) (Homo sapiens)


name: HSD17B13 binds lipid droplets (Saccharomyces cerevisiae)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Dictyostelium discoideum)


name: H(+)(in) + melibiose(in) = H(+)(out) + melibiose(out)


name: Cyclisation of GTP to precursor Z (Rattus norvegicus)


name: HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization (Dictyostelium discoideum)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + H(+) + phosphoethanolamine => 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O


name: FN1 binds Collagen types I-V, VII (Canis familiaris)


name: (2R)-2-hydroperoxydodecanoate => dodecanoate + O2


name: C3PO hydrolyzes cleaved passenger strand (Gallus gallus)


name: Phosphorylation of p-KIT on Y900 by Src kinases (Mus musculus)


name: androsterone + H(+) + NADPH => 5alpha-androstane-3alpha,17beta-diol + NADP(+)


name: Activation of Cdc42 by pVav1 (Rattus norvegicus)


name: DOLK phosphorylates DCHOL to DOLP (Xenopus tropicalis)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Drosophila melanogaster)


name: Necl-1:Nectin 3 trans heterodimer interaction (Canis familiaris)


name: Expression of TBX6 in paraxial mesoderm (Homo sapiens)


name: PP6-PPP6R3 dephosphorylates TERF2 (Bos taurus)


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Canis familiaris)


name: IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced (Homo sapiens)


name: 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Homo sapiens)


name: a triacylglycerol + H2O => a 1,3-diacylglycerol + a fatty acid + H(+)


name: 5-aminopentanal + H2O + NAD(+) = 5-aminopentanoate + 2 H(+) + NADH


name: dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2


name: 26S proteosome degrades ODC holoenzyme complex (Xenopus tropicalis)


name: cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine <=> 2'-O-methylcytidine(4) in tRNA(Pro) + H(+) + S-adenosyl-L-homocysteine


name: The phagophore extends from the PIP3-enriched structure (Rattus norvegicus)


name: ATP + L-proline <=> 3'-L-prolyl-AMP + diphosphate


name: Formation of Processive Complex (Caenorhabditis elegans)


name: DP2 receptor can bind PGD2 (Homo sapiens)


name: 2-hydroxy-2-(4-hydroxyphenyl)acetate + H(+) => 4-hydroxybenzyl alcohol + CO2


name: (2E,6E)-farnesyl diphosphate = diphosphate + pentalenene


name: 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA => a 1-acyl-sn-glycero-3-phosphate + hexadecanoyl-CoA


name: H2O + O2 + pyridoxal <=> 4-pyridoxate + H(+) + H2O2


name: NLRX1 inhibits IPS1 signaling (Gallus gallus)


name: PLC-gamma1 hydrolyses PIP2 (Xenopus tropicalis)


name: ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans (Homo sapiens)


name: PON1,3 hydrolyse ATVL to ATV (Mus musculus)


name: PDGFRs bind type II TKI (Canis familiaris)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Caenorhabditis elegans)


name: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + H(+) + 2 H2O => 2,4,6-trihydroxyphenylhexan-1-one + chloride + FADH2 + O2


name: a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + H(+) + NADPH => a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP(+)


name: TRPs transport extracellular Ca2+ to cytosol (Xenopus tropicalis)


name: Recruitment of elongation factors to form elongation complex (Caenorhabditis elegans)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Canis familiaris)


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Danio rerio)


name: 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+) => an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: thiamine + UTP <=> H(+) + thiamine diphosphate + UMP


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Mus musculus)


name: Dermatan sulfate can be further sulfated on position 2 of iduronate (Bos taurus)


name: WLS:WNT complex is internalized for maturation into exosomes (Sus scrofa)


name: H2O + triglucosyl-enterobactin => [N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]3 + H(+)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Canis familiaris)


name: PRICKLE1 is degraded by the proteasome (Mus musculus)


name: (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O => (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione


name: coelenterazine h dioxetanone => CO2 + excited coelenteramide h monoanion + H(+)


name: H2O + L-threonyl-L-threonine <=> 2 L-threonine


name: NMT1/2 transfer MYS to GNAT1 (Xenopus tropicalis)


name: 2-methylbutyl butanoate + CoA => 2-methylbutan-1-ol + butanoyl-CoA


name: p-Y389,400-RUFY1 binds PI3P (Homo sapiens)


name: Translocation of PDK1 to Plasma membrane (Homo sapiens)


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Drosophila melanogaster)


name: Active NIK phosphorylates IKKA dimer (Bos taurus)


name: FOXO1,FOXO3 bind ABCA6 gene promoter (Homo sapiens)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Canis familiaris)


name: SLIT2 binds Dystroglycan (Gallus gallus)


name: 1D-chiro-inositol + NAD(+) <=> H(+) + NADH + scyllo-inosine


name: cyclobis-(1->3)-alpha-D-isomaltosyl + H2O => alpha-isomaltosyl-(1->3)-isomaltose


name: UCP1 imports a proton (Xenopus tropicalis)


name: ADP + H(+) + O-phospho-L-serine => ATP + L-serine


name: chenodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP => chenodeoxycholate + UDP-alpha-D-glucuronate


name: pyridine + thiamine <=> 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine


name: snRNP nuclear import and release (Sus scrofa)


name: AH2 + menaquinone-9 = A + beta-dihydromenaquinone-9


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Canis familiaris)


name: 2 (S)-lactate(out) + thromboxane B2(in) => 2 (S)-lactate(in) + thromboxane B2(out)


name: a sphingoid 1-phosphate + H2O = a sphingoid base + phosphate


name: Follicle-stimulating hormone receptor can bind FSH (Canis familiaris)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Mus musculus)


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Dictyostelium discoideum)


name: Synthesis of ALAS2 nascent polypeptide (Gallus gallus)


name: p-T774-PKN1 phosphorylates CDC25C (Homo sapiens)


name: Activated PCLG1 dissociates from NTRK2 (Mus musculus)


name: SUMOylation of RAD52 with SUMO1 (Bos taurus)


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Canis familiaris)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Sus scrofa)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Sus scrofa)


name: Ubiquitinated IkB is degraded (Bos taurus)


name: Cis-homodimerization of nectins (Drosophila melanogaster)


name: L-threonate + NAD(+) = 2-dehydro-L-erythronate + H(+) + NADH


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Sus scrofa)


name: H antigen-sec translocates from Golgi lumen to extracellular region (Homo sapiens)


name: B4GAT1:LARGE transfers GlcA from UDP-GlcA to Xyl-GlcA (Rattus norvegicus)


name: Degradation multiubiquitinated Cyclin A (Mus musculus)


name: Exocytosis of specific granule lumen proteins (Mus musculus)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + sphing-4-enine = 1-O-alkyl-sn-glycero-3-phosphocholine + an N-acylsphing-4-enine + H(+)


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-4,8-dimethyldeca-4,8-dienoyl-CoA + NAD(+) => (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-4,8-dimethyldeca-4,8-dienoyl-CoA + H(+) + NADH


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Xenopus tropicalis)


name: an oxidized flavin + 2 H(+) + NADH => a reduced flavin + NAD(+)


name: 6-carboxy-5,6,7,8-tetrahydropterin + H(+) <=> 7-carboxy-7-deazaguanine + NH4(+)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP => 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Canis familiaris)


name: 2-oxoglutarate + H(+) = CO2 + succinate semialdehyde


name: DUOX1,2 reduce O2 to H2O2 (Rattus norvegicus)


name: (E,E)-piperoyl-AMP + diphosphate => (E,E)-piperate + ATP + H(+)


name: (2S,3E)-2-hydroxy-4-phenylbut-3-enenitrile => (E)-cinnamaldehyde + hydrogen cyanide


name: (2R,3S)-3-isopropylmalate + NAD(+) => (2S)-2-isopropyl-3-oxosuccinate + H(+) + NADH


name: Recruitment of PLCgamma to membrane (Homo sapiens)


name: GDIs block activation of RHOC (Canis familiaris)


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: 6-methyl-3,7-dioxodecanedioyl-CoA + CoA = 4-methyl-5-oxo-octanedioyl-CoA + acetyl-CoA


name: enzyme-thiol transhydrogenase (glutathione-disulfide) activity


name: AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Danio rerio)


name: SORD oxidizes D-sorbitol to Fru (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-octanoyl ethanolamine => H2O + N-octanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Sus scrofa)


name: p-STAT1 dimer binds KPNA1 (Mus musculus)


name: Methylation of GMP-cap by RNA Methyltransferase (Schizosaccharomyces pombe)


name: CO2 + deoxyviolacein + 2 H2O + NAD(+) => 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate


name: S-(hydroxymethyl)mycothiol => formaldehyde + mycothiol


name: REV1 recruits POLZ to (AP:Cyt)-DNA Template (Plasmodium falciparum)


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]3 + H(+) => Fe(III)-enterobactin + H2O


name: 3-phenylpropylamine + pyruvate <=> 3-phenylpropanal + L-alanine


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Sus scrofa)


name: PRODH oxidises L-Pro to 1PYR-5COOH (Dictyostelium discoideum)


name: Formation of CDK4/6:CCND complexes (Mus musculus)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Sus scrofa)


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Rattus norvegicus)


name: Liganded Gz-activating GPCR acts as a GEF for Gz (Drosophila melanogaster)


name: gypsogenin + O2 + reduced [NADPH--hemoprotein reductase] <=> gypsogenate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+)(out) + ubiquinol-8 => 2 H(+)(in) + H2 + ubiquinone-8


name: Phosphorylation of SLP-76 by p-SYK (Homo sapiens)


name: Interaction of SHP-1 or SHP-2 with phospho PD-1 (Rattus norvegicus)


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Canis familiaris)


name: Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Sus scrofa)


name: androst-4-ene-3,17-dione + H(+) + NADPH => 5beta-androstane-3,17-dione + NADP(+)


name: chloride(in) + 2 Na(+)(in) + sarcosine(in) => chloride(out) + 2 Na(+)(out) + sarcosine(out)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Bos taurus)


name: XYLB phosphorylates D-xylulose (Mus musculus)


name: 10-deoxysarpagine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sarpagine


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Plasmodium falciparum)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Mus musculus)


name: Interaction of NUMB with L1 (Homo sapiens)


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Xenopus tropicalis)


name: Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Sus scrofa)


name: a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)


name: Misfolded proteins:HDAC6:Dynein motor binds microtubule (Homo sapiens)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Saccharomyces cerevisiae)


name: [L-4-(L-arginin-2-N-yl)aspartate](n) + H2O <=> [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Xenopus tropicalis)


name: STARD10 binds LPCAT1 and PC (Homo sapiens)


name: (2S)-methylpentadecanoyl-CoA + O2 <=> 2-methyl-(2E)-pentadecenoyl-CoA + H2O2


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Dictyostelium discoideum)


name: GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Bos taurus)


name: DKK promotes clathrin-dependent internalization of LRP6 (Bos taurus)


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Caenorhabditis elegans)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Schizosaccharomyces pombe)


name: a globoside Gb4Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a globoside Forssman (d18:1(4E)) + H(+) + UDP


name: USP14 deubiquitinates NLRC5 (Canis familiaris)


name: chloride + L-tyrosine + NADP(+) => 3-chloro-L-tyrosine + NADPH


name: ATP + L-histidyl-[protein] <=> ADP + H(+) + N(tele)-phospho-L-histidyl-[protein]


name: Activated ATM phosphorylates ABL1 (Rattus norvegicus)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Caenorhabditis elegans)


name: XYLTs transfer Xyl to core protein (Danio rerio)


name: DDAH1 hydrolyses ADMA to DMA and L-Cit (Canis familiaris)


name: ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]


name: Removal of remaining Flap from the C-strand (Canis familiaris)


name: glucose 6-phosphate [cytosol] => glucose 6-phosphate [endoplasmic reticulum lumen] (Gallus gallus)


name: RHOD:GTP translocates to the endosome membrane (Mus musculus)


name: The Ligand:GPCR:G12/13 complex dissociates (Caenorhabditis elegans)


name: Activation of SHP2 through the binding to phospho-Gab1 (Mus musculus)


name: CaMKK autophosphorylates in the cytosol (Sus scrofa)


name: [thioredoxin]-dithiol + tert-butyl hydroperoxide <=> [thioredoxin]-disulfide + H2O + tert-butanol


name: p-S407-STAT6 is phosphorylated at Tyr641 (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate


name: H(+) + H2O + sepiapterin <=> NH4(+) + xanthopterin-B2


name: 6-acetamido-3-oxohexanoate + L-glutamate => 2-oxoglutarate + 6-acetamido-3-aminohexanoate


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Gallus gallus)


name: Vamp7 associated Lysosome to Plasma membrane transport (Dictyostelium discoideum)


name: a globoside NOR2 + H(+) + UDP => a globoside NORint + UDP-alpha-D-galactose


name: D-mannose + NADP(+) <=> 2-dehydro-D-glucose + H(+) + NADPH


name: FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling (Gallus gallus)


name: 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + H2O => (2R)-2-O-(alpha-D-mannosyl)-glycerate + phosphate


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Xenopus tropicalis)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) => (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH


name: AFG3L2 degrades mitochondrial inner membrane proteins (Dictyostelium discoideum)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (+)-copalyl diphosphate


name: RNF41 binds neuregulin-activated ERBB3 (Bos taurus)


name: UDP-N-acetyl-alpha-D-glucosamine <=> H2O + UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Rattus norvegicus)


name: PIAS2-2 SUMOylates THRA with SUMO1 (Bos taurus)


name: 3'-phosphoadenylyl sulfate(in) + adenosine 3',5'-bisphosphate(out) <=> 3'-phosphoadenylyl sulfate(out) + adenosine 3',5'-bisphosphate(in)


name: 3-oxoisoapionate 4-phosphate + ADP + H(+) => 3-oxoisoapionate + ATP


name: (indol-3-yl)acetate + 2 H(+) + NADH => H2O + indole-3-acetaldehyde + NAD(+)


name: 6-hydroxyphenazine-1-carboxylate + 2 H(+) + NADH + O2 = 1,6-dihydroxyphenazine + CO2 + H2O + NAD(+)


name: a 2'-deoxycytidine in double-stranded DNA + H(+) + H2O => a 2'-deoxyuridine in double-stranded DNA + NH4(+)


name: CYP26A1,B1,C1 4-hydroxylate atRA (Rattus norvegicus)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside + phosphate => beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + H2O


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Mus musculus)


name: Gt-GTP dissociates to GNAT1-GTP and GNB1:GNGT1 (Sus scrofa)


name: diphosphate + UMP <=> 5-phospho-alpha-D-ribose 1-diphosphate + uracil


name: inulobiose = alpha-D-fructofuranose-beta-D-fructofuranose 2',1:2,3'-dianhydride + H2O


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Drosophila melanogaster)


name: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: Inactivation of Wee1 kinase (Xenopus tropicalis)


name: 1(F)-beta-D-fructosylsucrose + sucrose = 1,6-kestotetraose + beta-D-glucose


name: Caspase-3 cleaves pro-interleukin-16 (Sus scrofa)


name: (R)-S-adenosyl-L-methionine + H2O <=> adenosine + H(+) + L-methionine


name: LRAT esterifies RBP2:atROL and FACYLs to atREs (Bos taurus)


name: Tankyrase ADP-ribosylates AXIN (Gallus gallus)


name: (6E)-8-hydroxygeraniol + NAD(+) => (6E)-8-oxogeraniol + H(+) + NADH


name: glyoxylate + L-ornithine <=> 5-amino-2-oxopentanoate + glycine


name: CYP17A1 17-hydroxylates P4 to 17aHPROG (Mus musculus)


name: PTGS2 dimer binds PTGS inhibitors (Canis familiaris)


name: Degradation of multiubiquitinated Cdh1 (Xenopus tropicalis)


name: FLNA binds PAK1 (Dictyostelium discoideum)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Sus scrofa)


name: inositol phosphoceramide synthase regulator activity


name: Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)


name: Phosphorylated ERF translocates to the cytosol (Homo sapiens)


name: 4-aminobutanoate(out) + chloride(out) + 2 Na(+)(out) <=> 4-aminobutanoate(in) + chloride(in) + 2 Na(+)(in)


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Sus scrofa)


name: (E)-(indol-3-yl)acetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> 1-aci-nitro-2-(1H-indol-3-yl)ethane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Sus scrofa)


name: RUNX1 and GATA1 bind the promoter of the MIR27A gene (Homo sapiens)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Mus musculus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Canis familiaris)


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] => (S)-eriodictyol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: MDM2 ubiquitinates JMY (Rattus norvegicus)


name: ATF6 (ATF6-alpha) translocates from the cytosol to the nucleus (Canis familiaris)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: GSTZ1 isomerizes 4-MAA (Xenopus tropicalis)


name: alpha-L-Rha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP + H(+) => alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose


name: LTC4S trimer transfers GSH to 7S(8)-epoxy-17(S)-HDHA to form RCTR1 (Canis familiaris)


name: (3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol <=> (-)-medicarpin + H2O


name: ATP + Cu(+)(in) + H2O => ADP + Cu(+)(out) + H(+) + phosphate


name: CFTR transits to the plasma membrane (Gallus gallus)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Drosophila melanogaster)


name: S-adenosyl-L-methionine + sarcosine = H(+) + N,N-dimethylglycine + S-adenosyl-L-homocysteine


name: POLD,POLE-mediated DNA strand displacement synthesis (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol => a 1,2-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: Activated FGFR1 binds SHC1 (Gallus gallus)


name: Homodimerization of VEGF proteins (Bos taurus)


name: Calmodulin activates Cam-PDE 1 (Canis familiaris)


name: Phosphorylation of E proteins by p38 MAPK (Homo sapiens)


name: Association of Emi1 with Cdc20 (Rattus norvegicus)


name: RHO1:GTP complex dissociates from RHOGEF2 (Drosophila melanogaster)


name: HOMER binds SHANK proteins (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: CREB3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Homo sapiens)


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Rattus norvegicus)


name: Cleavage of Procaspase-7 by the apoptosome (Danio rerio)


name: SULT1A3,4 dimers sulfate DA to DAOS (Danio rerio)


name: 1-hydroxy-2-naphthoate + 2 H(+) + NADH + O2 = CO2 + H2O + NAD(+) + naphthalene-1,2-diol


name: demethylmacrocin + S-adenosyl-L-methionine = H(+) + macrocin + S-adenosyl-L-homocysteine


name: FGAM + ATP => AIR + ADP + Pi (Xenopus tropicalis)


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Caenorhabditis elegans)


name: H2O + methyl acetate + NADP(+) => acetone + H(+) + NADPH + O2


name: (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NAD(+) => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH + uridine(54) in tRNA


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Rattus norvegicus)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Danio rerio)


name: SLC12A3 binds SLC12A3 inhibitors (Sus scrofa)


name: HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Rattus norvegicus)


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Caenorhabditis elegans)


name: biliverdin IXalpha + H(+) + NADH => (4Z,15Z)-bilirubin IXalpha + NAD(+)


name: Factor D cleaves C3b-bound Factor B (Homo sapiens)


name: RAC1 binds effectors at the plasma membrane (Homo sapiens)


name: carcinine + H(+) + holo-[peptidyl-carrier protein] => beta-alanyl-[peptidyl-carrier protein] + histamine


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Caenorhabditis elegans)


name: a ganglioside GD1a (d18:1(4E)) + H2O <=> a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate


name: (R)-noradrenaline + L-glutaminyl-[protein] = 5-(R)-noradrenalinyl-L-glutamyl-[protein] + NH4(+)


name: NCOA1 recruits EP300 to the ABCA1 promoter (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 => (13R)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Sus scrofa)


name: [(R)-3-hydroxyalkanoate](n) + a (3R)-3-hydroxyacyl-CoA <=> [(R)-3-hydroxyalkanoate](n+1) + CoA


name: KCNJs transport K+ from the extracellular region to cytosol (Rattus norvegicus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: TMEM55B translocates to the nucleus (Mus musculus)


name: Caspase mediated cleavage of HIP-55 (Homo sapiens)


name: H2O + nonane-4,6-dione <=> butanoate + H(+) + pentan-2-one


name: H(+) + L-arginine + NADH + O2 = H2O + N(omega)-hydroxy-L-arginine + NAD(+)


name: BLVRA:Zn2+, BLVRB reduce BV to BIL (Rattus norvegicus)


name: The proton is delivered to the matrix side (Homo sapiens)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Sus scrofa)


name: UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose (Homo sapiens)


name: HRSP12 deaminates 2AA to 2OBUTA (Canis familiaris)


name: L-seryl-[protein] + octanoyl-CoA => CoA + O-octanoyl-L-seryl-[protein]


name: PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Drosophila melanogaster)


name: 2 H(+) + N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine => guanosine(26) in tRNA + 2 S-adenosyl-L-methionine


name: FADH2 + O2 + styrene = (S)-styrene oxide + FAD + H(+) + H2O


name: 8-hydroxycopalyl diphosphate = cis-abienol + diphosphate


name: NMRK1 phosphorylates NR to yield NMN (Canis familiaris)


name: Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 (Homo sapiens)


name: SUMOylation of DDX5 with SUMO1 (Caenorhabditis elegans)


name: Interaction of MyoD:E protein with MEF2 (Danio rerio)


name: betaine aldehyde hydrate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => choline + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 3-oxocholan-24-oyl-CoA + NAD(+) => 3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Sus scrofa)


name: a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: (8E,10S)-10-hydroperoxy-octadeca-8-enoate => (9Z)-octadecenoate + O2


name: acetate + H(+) + methanol => H2O + methyl acetate


name: 2,3-dihydroxybenzoate + ATP + holo-[ACP] = 2,3-dihydroxybenzoyl-[ACP] + AMP + diphosphate


name: MLKL binds PDCD6IP and SDCBP (Mus musculus)


name: MRN complex binds shortened telomeres (Schizosaccharomyces pombe)


name: dTDP-6-deoxy-beta-L-talose + NADP(+) <=> dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH


name: propane-1,3-diamine + sym-homospermidine => putrescine + spermidine


name: NOX3 complex:RAC1:GTP generates superoxide from oxygen (Gallus gallus)


name: T2Rs bind bitter-tasting compounds (Gallus gallus)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Gallus gallus)


name: CD163 gene produces CD163 protein (Homo sapiens)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Gallus gallus)


name: Receptor FFAR2 binds carboxylates (Sus scrofa)


name: DLD dimer dehydrogenates dihydrolipoyl (Bos taurus)


name: (1S,2S,4R)-endo-fenchol + NAD(+) = (1S,4R)-fenchone + H(+) + NADH


name: H2O + triglucosyl-enterobactin = [N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]3 + H(+)


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Drosophila melanogaster)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: Thr-180 of ULK1 is phosphorylated (Dictyostelium discoideum)


name: calcitriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => alfacalcidol + O2 + reduced [NADPH--hemoprotein reductase]


name: 1,2-di-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+)


name: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)


name: epitestosterone 17-sulfate(out) + 2 Na(+)(out) => epitestosterone 17-sulfate(in) + 2 Na(+)(in)


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Homo sapiens)


name: p-S MAPKAPK5 phosphorylates HSPB1 (Danio rerio)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Saccharomyces cerevisiae)


name: 2-oxoglutarate(in) + H(+)(in) => 2-oxoglutarate(out) + H(+)(out)


name: 3-chlorocatechol + O2 <=> (2E,4Z)-2-chloromuconate + 2 H(+)


name: 4-nitrobenzaldehyde + H(+) + NADPH = 4-nitrobenzyl alcohol + NADP(+)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + ATP + H2O <=> 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + ADP + H(+) + phosphate


name: 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O + NAD(+) => 4beta-formylmethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADH + O2


name: 6alpha-hydroxytyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxotyphasterol + O2 + reduced [NADPH--hemoprotein reductase]


name: Pannexin 1/Pannexin2 mediated neuronal gap junction communication (Bos taurus)


name: SUMOylation of DDX5 with SUMO1 (Xenopus tropicalis)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + CMP-N-acetyl-beta-neuraminate => a ganglioside GM3 + CMP + H(+)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: ABC7, mABC1 and mABC2 mediate heme transport (Canis familiaris)


name: CHST2,5,6 transfer SO4(2-) to GlcNAc residues on keratan-PG to form KSPG (Bos taurus)


name: EPHX1 hydrates BaP4,5O to BaP4,5-DHD (Rattus norvegicus)


name: Association of Cdh1 with the APC/C (Mus musculus)


name: (9Z)-octadecen-1-ol + (9Z)-octadecenoyl-CoA => 1-O-(9Z)-octadecenyl (9Z)-octadecenoate + CoA


name: SUMOylation of PCNA with SUMO1 (Saccharomyces cerevisiae)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Gallus gallus)


name: Trimerization of cytosolic HSF1 (Rattus norvegicus)


name: hercynine + L-cysteine + O2 <=> H2O + S-(hercyn-2-yl)-L-cysteine S-oxide


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Homo sapiens)


name: UMPS dimer decarboxylates OMP to UMP (Drosophila melanogaster)


name: RHOJ GEFs activate RHOJ (Drosophila melanogaster)


name: a globoside GalGb4Cer (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a globoside MSGG (d18:1(4E)) + CMP + H(+)


name: O2 + reduced [NADPH--hemoprotein reductase] + taxa-4,11-diene <=> H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + taxa-4(20),11-dien-5alpha-ol


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA <=> (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA


name: Formation of NELF complex  (Mus musculus)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + UDP-alpha-D-galactose


name: GTP loading by Rheb (Dictyostelium discoideum)


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Canis familiaris)


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(36)-[histone H3] + O2 = CO2 + formaldehyde + L-lysyl(36)-[histone H3] + succinate


name: biphenyl-2,3-diol + O2 => 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+)


name: 2 chloride(out) + hydrogencarbonate(in) = 2 chloride(in) + hydrogencarbonate(out)


name: H(+) + N(6)-methyladenosine(1618) in 23S rRNA + S-adenosyl-L-homocysteine => adenosine(1618) in 23S rRNA + S-adenosyl-L-methionine


name: 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate = 20-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + UDP


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O <=> diphosphate + preaspterpenacid acid I


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Gallus gallus)


name: "Activator" RAF:YWHAB dimer binds RAS:GTP (Drosophila melanogaster)


name: (9Z)-octadecenoate + O2 = 10-hydroperoxy-(8E)-octadecenoate


name: (S)-norreticuline + S-adenosyl-L-methionine <=> (S)-norcodamine + H(+) + S-adenosyl-L-homocysteine


name: Activation of HCN channels (Rattus norvegicus)


name: formate + H(+) + UTP <=> CO2 + dUTP + H2O


name: 2'-O-methylcytidine(56) in tRNA + H(+) + S-adenosyl-L-homocysteine => cytidine(56) in tRNA + S-adenosyl-L-methionine


name: ATP + H2O + sulfate(out) <=> ADP + H(+) + phosphate + sulfate(in)


name: Phosphorylation of BIM by JNK (Homo sapiens)


name: Formation of ADAR2  homodimer (Rattus norvegicus)


name: CXXC1 and WDR82 bind SET1A complex (Sus scrofa)


name: Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Bos taurus)


name: STON2 is neddylated (Schizosaccharomyces pombe)


name: Formation of Processive Complex on the C-strand of the telomere (Homo sapiens)


name: 1-propanol + butanoyl-CoA <=> CoA + propyl butanoate


name: catechol + H(+) + NADPH => (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+)


name: nucleotide transmembrane transporter activity


name: dodecanoyl-CoA + L-seryl-[protein] = CoA + O-dodecanoyl-L-seryl-[protein]


name: Connexin 45/Connexin 36 mediated neuronal gap junction communication (Rattus norvegicus)


name: Association of Securin with Cdc20:APC/C complex (Gallus gallus)


name: Proteasome degrades polyubiquitinated PTEN (Caenorhabditis elegans)


name: all-trans-4,4'-diapolycopene + 4 FADH2 => 15-cis-4,4'-diapophytoene + 4 FAD + 4 H(+)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Dictyostelium discoideum)


name: Proteasome proteolyzes ub-HIF-alpha (Canis familiaris)


name: XDH dehydrogenates xanthine to form urate (Dictyostelium discoideum)


name: 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 = 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H(+) + H2O2


name: RHAG transports CO2 from cytosol to extracellular region (Danio rerio)


name: CIDEA:CIDEC binds lipid droplets (Drosophila melanogaster)


name: L-ascorbate(out) + monodehydro-L-ascorbate radical(in) => L-ascorbate(in) + monodehydro-L-ascorbate radical(out)


name: RUNX1:CBFB binds the SERPINB13 gene promoter (Homo sapiens)


name: Inactive G alpha (z) reassociates with G beta:gamma (Mus musculus)


name: all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = all-trans-3-hydroxyretinol + H2O + 2 oxidized [adrenodoxin]


name: AMP + diphosphate <=> 5-phospho-alpha-D-ribose 1-diphosphate + adenine


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Drosophila melanogaster)


name: 6-deoxy-6-sulfo-D-fructose + D-erythrose 4-phosphate <=> (2S)-3-sulfolactaldehyde + D-sedoheptulose 7-phosphate


name: RCE1 cleaves S-Farn proRAS proteins (Rattus norvegicus)


name: an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate => an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Saccharomyces cerevisiae)


name: Formation of the CI:SU(FU) complex (Drosophila melanogaster)


name: 4-aminobutanoate(out) + n H(+)(in) => 4-aminobutanoate(in) + n H(+)(out)


name: Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 (Xenopus tropicalis)


name: 3-oxo-(5Z)-dodecenoyl-[ACP] + CO2 + holo-[ACP] => (3Z)-decenoyl-[ACP] + H(+) + malonyl-[ACP]


name: beta-D-galactosyl-(1->4)-L-rhamnose + phosphate = alpha-D-galactose 1-phosphate + L-rhamnopyranose


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Canis familiaris)


name: MASTL phosphorylates ENSA (Canis familiaris)


name: 6-deoxo-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxy-28-nortyphasterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: menadiol + NAD(+) => H(+) + menadione + NADH


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: (5Z,8Z)-eicosadienoate + O2 <=> (5S)-hydroperoxy-(6E,8Z)-eicosadienoate


name: hapalindole U => 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole


name: beta-NGF dimer binds to TrkA receptor (Mus musculus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + cholesterol = an N-acylsphing-4-enine + cholesteryl 3-beta-D-glucoside


name: ADP + docosanoate(out) + H(+) + phosphate => ATP + docosanoate(in) + H2O


name: Expression of Carbonic Anhydrase IX (CA9) (Homo sapiens)


name: MKRN1 polyubiquitinates PTEN (Drosophila melanogaster)


name: RNASEL cleaves cellular ssRNA (Canis familiaris)


name: Co(II)-factor IV + S-adenosyl-L-homocysteine => Co(II)-factor III + H(+) + S-adenosyl-L-methionine


name: RAG1:RAG2 recombinase binds immunoglobulin kappa locus in a BRWD1-dependent manner (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + alpha,alpha-trehalose <=> 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+)


name: SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Bos taurus)


name: (R)-carnitine transmembrane transporter activity


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Rattus norvegicus)


name: an N-acylsphing-4-enine(in) + ATP + H2O = ADP + an N-acylsphing-4-enine(out) + H(+) + phosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: NICD4 traffics to the nucleus (Sus scrofa)


name: (25R)-3-oxocholest-4-en-26-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (25R)-3-oxocholest-4-en-26-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: dADP(out) + H(+)(out) + phosphate(in) <=> dADP(in) + H(+)(in) + phosphate(out)


name: 25-hydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (1S)-1,25-dihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin]


name: Integrin alphaIIb beta3 activation (Caenorhabditis elegans)


name: Kinesins bind microtubules (Canis familiaris)


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Bos taurus)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO2 + H2O + succinate


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Rattus norvegicus)


name: Defective LCT does not hydrolyze Lac (Homo sapiens)


name: Beta-catenin binds SOX proteins (Danio rerio)


name: AH2 + O2 + verruculide C => A + H2O + verruculide C epoxide


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Rattus norvegicus)


name: Recruitment of TAK1 kinase complex to oligo-K63-pUb-TRAF6 (Gallus gallus)


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Bos taurus)


name: Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)


name: a UDP-monosaccharide + diphosphate => a monosaccharide 1-phosphate + H(+) + UTP


name: 2-dehydro-L-idonate + H(+) + NADPH => L-idonate + NADP(+)


name: acetone + H(+) + NADH => NAD(+) + propan-2-ol


name: (6R)-L-erythro-6,7-dihydrobiopterin + H2O => (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin


name: Accessory proteins are recruited to the maturing virion (Homo sapiens)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Gallus gallus)


name: diphosphate + L-serine <=> H(+) + O-phospho-L-serine + phosphate


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Sus scrofa)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] = 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA <=> (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H2O


name: diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate <=> 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate


name: Parkin binds Ub:UBE2N:UBE2V1 (Canis familiaris)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Mus musculus)


name: NTPDase1 hydrolyzes nucleoside triphosphates (Homo sapiens)


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Canis familiaris)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Canis familiaris)


name: a ganglioside Ac-O-7-GD3 => a ganglioside Ac-O-8-GD3


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Canis familiaris)


name: 2-oxoglutarate + L-prolyl-[protein] + O2 <=> CO2 + succinate + trans-4-hydroxy-L-prolyl-[protein]


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Plasmodium falciparum)


name: Release of GABA at the synapse (Mus musculus)


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Xenopus tropicalis)


name: 4-methylpentan-2-one + hydrogen cyanide => (2S)-2-hydroxy-2,4-dimethylpentanenitrile


name: a ganglioside GD2 (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GD1b (d18:1(4E)) + H(+) + UDP


name: Re-integration of insulin receptor into plasma membrane (Danio rerio)


name: 4-methylene-L-glutamine + H2O <=> 4-methylene-L-glutamate + NH4(+)


name: PLK1 binds phosphorylated condensin II complex (Dictyostelium discoideum)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Rattus norvegicus)


name: CES2 hydrolyzes ASA- (Caenorhabditis elegans)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Canis familiaris)


name: ATP + beta-citrylglutamate(in) + H2O => ADP + beta-citrylglutamate(out) + H(+) + phosphate


name: 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate => 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2


name: [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate => [(1->3)-beta-D-glucosyl](n) + phosphate


name: (2E)-tetradecenoyl-[ACP] + H(+) + NADPH => NADP(+) + tetradecanoyl-[ACP]


name: RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Dictyostelium discoideum)


name: 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] <=> coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Xenopus tropicalis)


name: Melanin-concentrating hormone receptors bind MCH (Xenopus tropicalis)


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Homo sapiens)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Gallus gallus)


name: ATXN3 binds RAD23 (Caenorhabditis elegans)


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Rattus norvegicus)


name: E2F6 binds the PRC1 complex (Drosophila melanogaster)


name: acetyl-CoA + 2 H(+) + 3 malonyl-CoA => 3 CO2 + 4 CoA + orsellinate


name: Photons induce isomerization of 11c-retinyl to at-retinyl (Caenorhabditis elegans)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Danio rerio)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Dictyostelium discoideum)


name: glutaryl-CoA + L-lysyl-[protein] <=> CoA + H(+) + N(6)-glutaryl-L-lysyl-[protein]


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Gallus gallus)


name: IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Canis familiaris)


name: Inactive G alpha (i) reassociates with G beta:gamma (Homo sapiens)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Mus musculus)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Mus musculus)


name: Caspase mediated cleavage of alpha-II-Fodrin (Gallus gallus)


name: anthranilate + 2 ATP + L-tryptophan = (R)-benzodiazepinedione + 2 AMP + 2 diphosphate + H(+)


name: p62 links damaged mitochondria to LC3 (Gallus gallus)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Bos taurus)


name: Recruitment of STAT2 to p-IFNAR1 (Sus scrofa)


name: ULK1 phosphorylates RIPK1 at S357 (Canis familiaris)


name: Endocytic Uptake of HCMV Virion (Homo sapiens)


name: vascular endothelial growth factor receptor 2 binding


name: 1-chloro-3-nitrobenzene + NADH + O2 => 4-chlorocatechol + NAD(+) + nitrite


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Bos taurus)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Saccharomyces cerevisiae)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + octadecanoyl-CoA <=> 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: Endocytosis of TRAM (TICAM2) (Canis familiaris)


name: Association of procollagen type I (Rattus norvegicus)


name: N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: acetyl phosphate + CO2 + H2O2 => H(+) + O2 + phosphate + pyruvate


name: all-trans-4,4'-diapo-zeta-carotene + FADH2 => all-trans-4,4'-diapophytofluene + FAD + H(+)


name: ISGylation of PKR (Caenorhabditis elegans)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Bos taurus)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Homo sapiens)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)


name: beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate


name: UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Bos taurus)


name: Synthesis of SARS-CoV-1 plus strand subgenomic mRNAs (Homo sapiens)


name: GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Rattus norvegicus)


name: adenosine(58) in tRNA + CO2 + formaldehyde + succinate => 2-oxoglutarate + N(1)-methyladenosine(58) in tRNA + O2


name: Recruitment of DNA2 endonuclease to the C strand (Homo sapiens)


name: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O = alpha-D-ribose 1,5-bisphosphate + H(+)


name: "phosphoribosyl 1,2-cyclic phosphate phosphodiesterase"


name: RRAGC,D hydrolyzes GTP (Canis familiaris)


name: menaquinol-4 + NAD(+) => H(+) + menaquinone-4 + NADH


name: a fatty acid(out) + ATP + H2O => a fatty acid(in) + ADP + H(+) + phosphate


name: 16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate <=> 16alpha,17beta-estriol 16-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: P4HB binds Collagen chains (Rattus norvegicus)


name: CDSN binds the cornified envelope (Canis familiaris)


name: [phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate


name: USP43 binds ISG:K164,ISG:K168-PCNA (Sus scrofa)


name: (20S)-ginsenoside R1 + H2O = (20S)-ginsenoside Rg1 + D-xylose


name: ATP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine = ADP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H(+) + phosphate


name: 3',3',3'-cAAG + 3 diphosphate => 2 ATP + GTP


name: p-DAPP1 (p-BAM32) binds PLCG2 (Saccharomyces cerevisiae)


name: carboxynorspermidine + H(+) = CO2 + norspermidine


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Sus scrofa)


name: D-glycero-D-manno-heptose 1,7-bisphosphate + H2O = D-glycero-D-manno-heptose 1-phosphate + phosphate


name: guanosine(in) + H(+)(out) => guanosine(out) + H(+)(in)


name: mesaconate + NH4(+) => (2S,3S)-3-methyl-L-aspartate


name: (5R)-5-hydroxy-L-lysyl-[collagen] + UDP-alpha-D-galactose = (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + H(+) + UDP


name: GAPDH tetramers reduce 1,3BPG to GA3P (Rattus norvegicus)


name: SUMOylation of TOPORS with SUMO1 (Bos taurus)


name: N-glycan trimming of Spike (Homo sapiens)


name: SCARB1:ligand is endocytosed (Mus musculus)


name: H2O + L-cystine + O2 => (2R)-2-amino-2-carboxylatoethyl-disulfanyl-oxopropanoate + H2O2 + NH4(+)


name: IKBA is phosphorylated by Phospho IKKB kinase (Gallus gallus)


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Sus scrofa)


name: Nuclear translocation of catalytic domain of Mst3 (Schizosaccharomyces pombe)


name: CoA + H(+) + N-octadecanoyl-serotonin => octadecanoyl-CoA + serotonin


name: p-Y389,400-RUFY1 translocates from cytosol to early endosome membrane (Homo sapiens)


name: 2'-deoxyadenosine + ATP = ADP + dAMP + H(+)


name: diphosphate + P(1),P(4)-bis(5'-guanosyl) tetraphosphate => 2 GTP + H(+)


name: 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Saccharomyces cerevisiae)


name: Palmostatin B binds RAS depalmitoylases (Mus musculus)


name: p-STAT1dimer:KPNA1 binds KPNB1 (Drosophila melanogaster)


name: 3-hydroxycyclohexanone + A => AH2 + cyclohexane-1,3-dione


name: IKBA is phosphorylated by Phospho IKKB kinase (Bos taurus)


name: GRB2:SOS interacts with p-KIT (Gallus gallus)


name: D-arabinono-1,4-lactone + H(+) + NADPH => D-arabinose + NADP(+)


name: 2-oxosuccinamate + an L-alpha-amino acid => a 2-oxocarboxylate + L-asparagine


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Bos taurus)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Sus scrofa)


name: 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+) => H(+) + NADPH + O2 + phenylacetyl-CoA


name: 9beta-pimara-7,15-dien-19-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase]


name: bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer (Bos taurus)


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Bos taurus)


name: p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Sus scrofa)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Rattus norvegicus)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Caenorhabditis elegans)


name: CoA + H(+) + N-(tetracosenoyl)-sphing-4-enine => sphing-4-enine + tetracosenoyl-CoA


name: (16R)-deshydroxymethyl-stemmadenine + formate + NADP(+) => 3,17-didehydrostemmadenine + H2O + NADPH


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Rattus norvegicus)


name: Inactivation of Wee1 kinase (Canis familiaris)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+) + octadecanoate => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O


name: H2O + O-(ADP-D-ribosyl)-L-seryl-[protein] = ADP-D-ribose + L-seryl-[protein]


name: (2S)-2-amino-4-deoxychorismate + H2O <=> (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxyate + pyruvate


name: Coumarin is 7-hydroxylated by CYP2A6 (Rattus norvegicus)


name: 3-oxo-(5Z-tetradecenoyl)-CoA + CoA <=> (3Z)-dodecenoyl-CoA + acetyl-CoA


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O = a 2'-deoxyribonucleoside 5'-phosphate + diphosphate + H(+)


name: a 1-acyl-sn-glycero-3-phosphate + holo-[ACP] => a fatty acyl-[ACP] + sn-glycerol 3-phosphate


name: (3S)-hydroxyoctadecanoyl-CoA + NAD(+) <=> 3-oxooctadecanoyl-CoA + H(+) + NADH


name: 2-oxospirilloxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2'-hydroxy-2-oxospirilloxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ADP + H(+) + phosphate + sphinganine(out) => ATP + H2O + sphinganine(in)


name: a (3R)-3-hydroxyacyl-CoA <=> a (3S)-3-hydroxyacyl-CoA


name: a neolactoside IV(3)-alpha-NeuAc-nLc4Cer + GDP-beta-L-fucose <=> a neolactoside IV(3)-alpha-NeuNAc,III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: (2E,9Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein] => (9Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation  (Rattus norvegicus)


name: N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+) => a 1,2-diacyl-sn-glycerol + CDP-choline


name: allocholoyl-CoA + deoxycholate => allocholate + deoxycholoyl-CoA


name: Fromation of the preholoimmunoproteasome (Caenorhabditis elegans)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: CHEK1 phosphorylates RAD51 (Schizosaccharomyces pombe)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Danio rerio)


name: chloride + L-tyrosine + NADP(+) = 3-chloro-L-tyrosine + NADPH


name: (2E,6E)-farnesyl diphosphate = (1R,4R,5S)-(-)-guaia-6,10(14)-diene + diphosphate


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Gallus gallus)


name: NH4(+) + pentanoate => H2O + pentanamide


name: Association of Cdh1 with the APC/C (Drosophila melanogaster)


name: Phenol can form a sulfate conjugate (Mus musculus)


name: 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose <=> 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+)


name: citrate(in) + trans-aconitate(out) => citrate(out) + trans-aconitate(in)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Saccharomyces cerevisiae)


name: SCF:FBXL7 binds AURKA (Schizosaccharomyces pombe)


name: hydroxyacetone + NAD(+) => H(+) + methylglyoxal + NADH


name: RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Bos taurus)


name: TORC2 complex phosphorylates SGK1 (Saccharomyces cerevisiae)


name: ATP + Cd(2+)(in) + H2O = ADP + Cd(2+)(out) + H(+) + phosphate


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Canis familiaris)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Caenorhabditis elegans)


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Rattus norvegicus)


name: RPE dimers isomerise RU5P to XY5P (Sus scrofa)


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Xenopus tropicalis)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Danio rerio)


name: diuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 3-(3,4-dichlorophenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Vamp2 associated secretory vesicle to plasma membrane transport (Bos taurus)


name: 2,5-didehydro-D-gluconate + H(+) + NADH => 5-dehydro-D-gluconate + NAD(+)


name: D-serine(out) + L-alanine(in) + Na(+)(in) => D-serine(in) + L-alanine(out) + Na(+)(out)


name: Formation of pre-mRNPs (Caenorhabditis elegans)


name: 4 H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) <=> 4 beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Drosophila melanogaster)


name: a mannosylinositol-1-phosphoceramide + GDP + H(+) => an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose


name: Excess homocysteine yields homolanthionine and H2S (Dictyostelium discoideum)


name: trans,octa-cis-decaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine <=> N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol + UMP


name: NPM1-ALK fusion dimer binds SKP1:CUL1:RBX1:ZC3HC1 (Homo sapiens)


name: EP1 receptor can bind PGE2 (Rattus norvegicus)


name: BLM mediates dissolution of double Holliday junction (Homo sapiens)


name: 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 = 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Canis familiaris)


name: Endocytosis of TLR4:LY96:LPS:CD14 (Rattus norvegicus)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)


name: a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + L-lysyl-[protein] => a 5'-end diphospho-adenosine in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein]


name: ATP + kanosamine => ADP + D-kanosamine 6-phosphate + H(+)


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Canis familiaris)


name: Removal of miRNA passenger strand (Drosophila melanogaster)


name: SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Canis familiaris)


name: MITF-M-dependent PMEL gene expression (Homo sapiens)


name: a ganglioside GD1a + N-acetylneuraminate => a ganglioside GT1a + H2O


name: 5alpha-cholesta-7,24-dien-3beta-ol + H(+) + NADPH + O2 => 7-dehydrodesmosterol + 2 H2O + NADP(+)


name: CALR, TAP, TAPBP dissociate from SEC22B:STX4 (Homo sapiens)


name: 1D-myo-inositol 2,3-bisphosphate + H2O = 1D-myo-inositol 2-phosphate + phosphate


name: (R)-carnitine(in) + glutarate(out) => (R)-carnitine(out) + glutarate(in)


name: NFE2 binds the beta globin locus control region (Rattus norvegicus)


name: (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H(+) + NADPH => (3E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + NADP(+)


name: NR1H2,3 binds the ARL4C gene (Homo sapiens)


name: Unknown pPPP phosphatase dephosphorylates pPPP to pPNOL (Homo sapiens)


name: RUNX1 binds the core TAL1 complex (Gallus gallus)


name: (9Z)-hexadecenoyl-CoA + hexadecan-1-ol <=> 1-O-hexadecyl (9Z)-hexadecenoate + CoA


name: 2-phosphoglycerate <=> phosphoenolpyruvate + H2O (Gallus gallus)


name: 2-oxoglutarate + L-tyrosine => 3-(4-hydroxyphenyl)pyruvate + L-glutamate


name: Fillagrin and keratin intermediate filaments polymerize forming a network (Gallus gallus)


name: (3R)-hydroxy-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA => (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H2O


name: AMP + diphosphate + propanoyl-CoA => ATP + CoA + propanoate


name: 2 H(+) + Mg-protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 O2 => 3,8-divinyl protochlorophyllide a + 5 H2O + 3 NADP(+)


name: Formation of ORC(1-5) complex (Gallus gallus)


name: 2-phenylacetate + CoA + H(+) => H2O + phenylacetyl-CoA


name: DHAP is converted to 1-acyl GO3P by GNPAT (Caenorhabditis elegans)


name: OGG1beta translocates to mitochondria (Saccharomyces cerevisiae)


name: 2 Na(+)(out) + tauroallocholate(out) <=> 2 Na(+)(in) + tauroallocholate(in)


name: SUMOylation of TFAP2B with SUMO1 (Homo sapiens)


name: RHOA:GTP binds RHPN1 or RHPN2 (Sus scrofa)


name: SYK activation by SRC (Canis familiaris)


name: Coumarin is 7-hydroxylated by CYP2A6 (Mus musculus)


name: ADP + H(+) + N(omega)-phospho-L-arginyl-[protein] => ATP + L-arginyl-[protein]


name: TBK1 phosphorylates STAT6 at Ser407 (Homo sapiens)


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Xenopus tropicalis)


name: 2,3-dihydrobiochanin A + NADP(+) = biochanin A + 2 H(+) + NADPH


name: an aromatic primary alcohol + NAD(+) <=> an aromatic aldehyde + H(+) + NADH


name: H(+) + NAD(+) + reduced [4Fe-4S]/[3Fe-4S]-[ferredoxin] <=> NADH + oxidized [4Fe-4S]/[3Fe-4S]-[ferredoxin]


name: GLI proteins bind SUFU (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + decan-1-ol <=> 1-O-decyl-(9Z)-octadecenoate + CoA


name: acetyl-CoA + cysteamine => CoA + S-acetylcysteamine


name: alcohol-forming very long-chain fatty acyl-CoA reductase activity


name: ATP + D-cystine(out) + H2O => ADP + D-cystine(in) + H(+) + phosphate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + FAD + H(+) => (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + FADH2


name: A + a 3-oxo-Delta(1)-steroid + H2O => a steroid 1,3-dione + AH2


name: AFG3L2 binds mitochondrial matrix proteins (Sus scrofa)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Dictyostelium discoideum)


name: paracellular tight junction channel activity


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Canis familiaris)


name: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate


name: H2O + N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine => H(+) + N-acyl-15-methylhexadecasphing-4-enine + phosphocholine


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)


name: PTK6 phosphorylates KHDRBS1 (Sus scrofa)


name: Keratin filament formation (Homo sapiens)


name: 3'-dephospho-CoA + ATP => ADP + CoA + H(+)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Drosophila melanogaster)


name: 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA => (9Z)-octadecenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine


name: ABCA12 transports lipids from cytosol to extracellular region (Plasmodium falciparum)


name: a 21-hydroxy-C21-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => a C21-steroid + O2 + reduced [NADPH--hemoprotein reductase]


name: FKBP1A binds tacrolimus (Xenopus tropicalis)


name: (1S,3bR,4R,5aR,9aR,9bR,11aS)-1-(1-hydroxy-4-oxobutan-2-yl)-3b,6,6,9a,11a-pentamethyl-7-oxo-1H,2H,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-4-yl acetate + 2-oxoglutarate + O2 = azadirone + CO2 + 2 H2O + succinate


name: 2 H(+) + H2O + N-hydroxy-L-pentahomomethionine + oxidized [NADPH--hemoprotein reductase] => L-pentahomomethionine + O2 + reduced [NADPH--hemoprotein reductase]


name: 22-hydroxydocosanoate + NAD(+) => 22-oxodocosanoate + H(+) + NADH


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Canis familiaris)


name: Expression of PCDH19 in the nephric duct (Homo sapiens)


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (23S)-23,25-dihydroxycalciol + H2O + 2 oxidized [adrenodoxin]


name: propanoate + pyruvate => (2R,3S)-2,3-dimethylmalate


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Homo sapiens)


name: AMP(in) + UDP-alpha-D-galactose(out) => AMP(out) + UDP-alpha-D-galactose(in)


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Bos taurus)


name: SPPL2a/b cleaves TNF(1-76) (Xenopus tropicalis)


name: ABHD4 hydrolyses NAPE (Saccharomyces cerevisiae)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-2,3-cyclic phosphate + ethanolamine


name: Loading of PCNA - Sliding Clamp Formation (Plasmodium falciparum)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Sus scrofa)


name: delphinidin + UDP-alpha-D-galactose = delphinidin 3-O-beta-D-galactoside + H(+) + UDP


name: STAB2:ligand is endocytosed (Canis familiaris)


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Drosophila melanogaster)


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 => 8-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate


name: MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Danio rerio)


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Saccharomyces cerevisiae)


name: STARD5 binds DCA, LCA (Rattus norvegicus)


name: Importin-8 imports AGO2:miRNA into the nucleus (Sus scrofa)


name: HLCS biotinylates 6xMCCC1:6xMCCC2 (Rattus norvegicus)


name: Pellino ubiquitinates IRAK1 (Drosophila melanogaster)


name: Parathyroid hormone receptor can bind parathyroid hormone (Danio rerio)


name: Dissociation of L13a from the 60s ribosomal subunit (Dictyostelium discoideum)


name: (S)-reticuline + S-adenosyl-L-methionine => (S)-laudanine + H(+) + S-adenosyl-L-homocysteine


name: The CDC25A gene transcription is stimulated by MYC and E2F1 and inhibited by the DREAM complex (Homo sapiens)


name: acetyl-CoA + H2O => acetate + CoASH + H+ (Sus scrofa)


name: (E)-sinapyl alcohol + A => (E)-sinapaldehyde + AH2


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Bos taurus)


name: estrone 3-sulfate(out) + L-glutamate(in) => estrone 3-sulfate(in) + L-glutamate(out)


name: FLIP(S) and procaspase-8 form heterodimer (Canis familiaris)


name: acetyl-CoA + N-terminal L-valyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-valyl-[protein]


name: (E)-cinnamaldehyde + hydrogen cyanide => (2S,3E)-2-hydroxy-4-phenylbut-3-enenitrile


name: USP16,USP21 deubiquitinate Histone H2A (Bos taurus)


name: 2 H(+) + O2 + 2 sulochrin <=> 2 (2R)-bisdechlorogeodin + 2 H2O


name: H2O + N-(octadecanoyl)-sphing-4-enine-1-phosphocholine = H(+) + N-octadecanoylsphing-4-enine + phosphocholine


name: a monoacylglycerol + H2O => a fatty acid + glycerol + H(+)


name: NUMB:ITCH ubiquitinates GLI1 (Gallus gallus)


name: TBP and TFIIA bind TATA box on  ESR1:estrogen bound TFF1 gene promoter (Bos taurus)


name: Cysteine is degraded to serine and H2S (Bos taurus)


name: 2xENPP1 hydrolyzes FAD to FMN (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: Heterodimerization of CEACAMs (Mus musculus)


name: H(+)(out) + L-galactonate(out) => H(+)(in) + L-galactonate(in)


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + UDP-alpha-D-glucuronate = 15-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + UDP


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Rattus norvegicus)


name: (1R,4R)-5-oxo-1,2-campholide = [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Rattus norvegicus)


name: H(+)(in) + L-histidine(in) + L-ornithine(out) => H(+)(out) + L-histidine(out) + L-ornithine(in)


name: a ganglioside Gal-GD1b (d18:1(4E)) + UDP-alpha-D-galactose <=> a ganglioside GalGal-GD1b (d18:1(4E)) + H(+) + UDP


name: 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + H2O <=> (2R)-2-O-(alpha-D-mannosyl)-glycerate + phosphate


name: PDPK1 (PDK1) phosphorylates PKN2 on threonine-816 (Bos taurus)


name: RAC1:GTP binds NOX1 complex (Gallus gallus)


name: SLCO2B1 has a narrow substrate specificity (Mus musculus)


name: MRE11 binds cytosolic DNA (Schizosaccharomyces pombe)


name: Surface deployment of platelet alpha granule membrane components (Saccharomyces cerevisiae)


name: SPRTN binds monoUb:K164-PCNA associated with POLH (Sus scrofa)


name: p-PKR dimer phosphorylates CDK1 (Danio rerio)


name: succinate-semialdehyde dehydrogenase (NADP+) activity


name: D-arabino-hex-3-ulose 6-phosphate => beta-D-fructose 6-phosphate


name: ATP + N-(acetyl)-sphing-4-enine <=> ADP + H(+) + N-(acetyl)-sphing-4-enine-1-phosphate


name: RHOD binds effectors at the endosome membrane (Rattus norvegicus)


name: a peptide antigen(in) + ATP + H2O <=> a peptide antigen(out) + ADP + H(+) + phosphate


name: Oxidation of 22beta-hydroxycholesterol to 20alpha,22beta-hydroxycholesterol (Homo sapiens)


name: RIPK1:RIPK3 oligomerizes to form amyloid-like fibrils (Homo sapiens)


name: (6E)-8-hydroxygeraniol + NADP(+) = (6E)-8-oxogeraniol + H(+) + NADPH


name: Autocatalytic phosphorylation of FGFR3c (Mus musculus)


name: 3-(4-hydroxyphenyl)pyruvate + H(+) <=> (4-hydroxyphenyl)acetaldehyde + CO2


name: Gq activation by TP receptor (Bos taurus)


name: Deacetylation of cleaved cohesin (Canis familiaris)


name: FN3KRP phosphorylates PsiAm, RibAm (Canis familiaris)


name: PXLP-K333-GADL1 decarboxylates acidic AAs (Canis familiaris)


name: 3alpha-hydroxy-5alpha-androstane 17-O-(beta-D-glucuronate) + NADP(+) => 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + H(+) + NADPH


name: Export of peptide loaded MHC class I complex to PM (Homo sapiens)


name: an aldehyde + H2O + NADP(+) = a carboxylate + 2 H(+) + NADPH


name: ALK autophosphorylation  (Rattus norvegicus)


name: WNT5A binds FZD and ROR receptors (Gallus gallus)


name: MAPK12 phosphorylates PTPN3 (Xenopus tropicalis)


name: H2O + N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein] <=> N(6)-(D-erythrulosyl)-L-lysyl-[protein] + phosphate


name: ATP + D-glucose(out) + H2O => ADP + D-glucose(in) + H(+) + phosphate


name: 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 (Bos taurus)


name: cAMP degradation by Phosphodiesterases (Danio rerio)


name: ATP + CoA + decanoate => AMP + decanoyl-CoA + diphosphate


name: histone H4R3 arginine deiminase activity


name: (20S)-20-O-(beta-D-glucosyl)-3-hydroxydammarene + O2 + reduced [NADPH--hemoprotein reductase] = (20S)-ginsenoside C-K + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: beta-D-fructose 1-phosphate => D-glyceraldehyde + dihydroxyacetone phosphate


name: Activated FGFR4 phosphorylates PPTN11 (Drosophila melanogaster)


name: ATP + H(+) + L-tyrosine + NADPH => AMP + diphosphate + L-tyrosinal + NADP(+)


name: galactarate(in) + H(+)(in) => galactarate(out) + H(+)(out)


name: (11Z,14Z)-eicosadienoyl-CoA + AH2 + O2 = (5Z,11Z,14Z)-eicosatrienoyl-CoA + A + 2 H2O


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Schizosaccharomyces pombe)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Bos taurus)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Drosophila melanogaster)


name: D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H(+) + H2O2


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Dictyostelium discoideum)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Xenopus tropicalis)


name: "endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase"


name: Procaspase 9 forms dimer (Rattus norvegicus)


name: alpha-D-glucose 1-phosphate + alpha-maltohexaose => alpha-maltoheptaose + phosphate


name: C5b:C6:C7 translocates to the plasma membrane (Canis familiaris)


name: FPR is a receptor for formyl peptides (Mus musculus)


name: 4-hydroxyestrone + UDP-alpha-D-glucuronate => estrone 4-O-(beta-D-glucuronate) + H(+) + UDP


name: GBA1:SAPC hydrolyzes GlcCer (Drosophila melanogaster)


name: CES1 hydrolyses sacubitril to sacubitrilat (Mus musculus)


name: Dephosphorylation of AKT by PP2A (Caenorhabditis elegans)


name: D-glucose(out) + H(+)(in) <=> D-glucose(in) + H(+)(out)


name: cyathadiol + O2 + reduced [NADPH--hemoprotein reductase] = cyathatriol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PTPN7 binds p-T,Y-MAPK (Schizosaccharomyces pombe)


name: Autophosphorylation of PAK1,2,3 (Canis familiaris)


name: Tyrosine phosphorylation of CRMPs by Fes (Homo sapiens)


name: NAAA hydrolyses NAEs to FAs and ethanolamine (Homo sapiens)


name: 1-O-(alk-1-enyl)-sn-glycero-3-phosphate + H2O = 1-O-(alk-1-enyl)-sn-glycerol + phosphate


name: 3-formylthiophene + hydrogen cyanide = (2S)-2-hydroxy-2-(thiophen-3-yl)acetonitrile


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Drosophila melanogaster)


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Bos taurus)


name: (13Z)-docosenoyl-CoA + H(+) + malonyl-CoA <=> (15Z)-3-oxotetracosenoyl-CoA + CO2 + CoA


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Xenopus tropicalis)


name: EHMT1:EHMT2 methylates IL8 promoter (Canis familiaris)


name: adenosine 3',5'-bisphosphate + an 11-sulfojasmonate + H(+) => 3'-phosphoadenylyl sulfate + an 11-hydroxyjasmonate


name: EXT1:EXT2 transfers GlcA to heparan (Canis familiaris)


name: outward rectifier potassium channel activity


name: Cleavage of uracil by MBD4 glycosylase (Sus scrofa)


name: beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine + H2O = D-glucosamine + N-acetyl-D-glucosamine


name: factor Va + factor Xa -> Va:Xa complex (prothrombinase) (Bos taurus)


name: Exocytosis of specific granule lumen proteins (Xenopus tropicalis)


name: SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) (Caenorhabditis elegans)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O = a 5'-end phospho (purine-ribonucleoside) in mRNA + 2 H(+) + N(7)-methyl-GDP


name: a globoside Gb3Cer (d18:1(4E)) + H2O <=> a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + D-galactose


name: Interleukin-5 is a homodimer (Canis familiaris)


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Canis familiaris)


name: RAC2 GEFs activate RAC2 (Rattus norvegicus)


name: CDK5:p25 translocates to the nucleus (Homo sapiens)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Sus scrofa)


name: CRHR2-2 binds CRH,UCN,UCN2,UCN3 (Canis familiaris)


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Bos taurus)


name: DNA polymerase alpha:primase binds at the origin (Bos taurus)


name: Activation of Cdc42 by pVav1 (Sus scrofa)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Sus scrofa)


name: (11Z)-eicosenoyl-CoA + H(+) + malonyl-CoA = (13Z)-3-oxodocosenoyl-CoA + CO2 + CoA


name: PG and CDP-DAG are converted to CL by CRLS1 (Saccharomyces cerevisiae)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Canis familiaris)


name: 1-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + 1-O-alkyl-sn-glycero-3-phosphoethanolamine <=> 1-O-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-O-alkyl-sn-glycero-3-phosphocholine


name: IL20 binds IL20RA:JAK1:IL20RB (Gallus gallus)


name: CDC42 GEFs activate CDC42 (Xenopus tropicalis)


name: glycyl-L-glutamine(in) + H(+)(in) => glycyl-L-glutamine(out) + H(+)(out)


name: 2,5-dihydroxypyridine + O2 => H(+) + N-formylmaleamate


name: Follitropin is a heterodimer (Danio rerio)


name: TP receptor can bind thromboxane (Mus musculus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Drosophila melanogaster)


name: bonnadiene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: (4R)-hydroxysphinganine + octadecanoyl-CoA = CoA + H(+) + N-octadecanoyl-(4R)-hydroxysphinganine


name: CYP3A43 6b-hydroxylates TEST (Canis familiaris)


name: Formation of Elongin BC complex (Homo sapiens)


name: (+)-lariciresinol + H(+) + NADPH => (-)-secoisolariciresinol + NADP(+)


name: GABA loaded synaptic vesicle Docking and Priming (Homo sapiens)


name: SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Homo sapiens)


name: a sphingoid base + ATP => a sphingoid 1-phosphate + ADP + H(+)


name: dihydroxyacetone phosphate + menaquinol-8 => menaquinone-8 + sn-glycerol 3-phosphate


name: 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH => 2-dehydro-3-deoxy-L-rhamnonate + NAD(+)


name: inorganic diphosphate phosphatase activity


name: BTK in active Gq-BTK complex is activated (Rattus norvegicus)


name: 3-aminobutan-1-ol + H2O + NAD(+) = 4-hydroxybutan-2-one + H(+) + NADH + NH4(+)


name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Sus scrofa)


name: Extracellular BTD hydrolyses BCTN (Rattus norvegicus)


name: Parkin binds Ub:UBE2N:UBE2V1 (Saccharomyces cerevisiae)


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Xenopus tropicalis)


name: LEAP2 binds bacteria (Rattus norvegicus)


name: A + Fe(II)-heme o + H2O => AH2 + Fe(II)-heme i


name: 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: ADP + an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+) => ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A


name: CHRM4 binds CHRM4 antagonists (Sus scrofa)


name: benzoyl-CoA + ethanol => benzyl acetate + CoA


name: a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O <=> a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)


name: diosgenin 3-O-beta-D-glucoside + 2 L-rhamnopyranose => dioscin + 2 H2O


name: Caspase mediated cleavage of beta-catenin (Bos taurus)


name: TP53 stimulates FANCC expression (Homo sapiens)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 12-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RAS GAPs stimulate RAS GTPase activity (Mus musculus)


name: Liganded Gs-activating GPCRs bind inactive heterotrimeric Gs (Homo sapiens)


name: 3-oxo-(9Z)-hexadecenoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxy-(9Z)-hexadecenoyl-[ACP] + NADP(+)


name: 2 CO2 + 3 CoA + triacetate lactone => acetyl-CoA + 2 H(+) + 2 malonyl-CoA


name: a di-trans,poly-cis-dolichyl phosphate + CDP + H(+) => a di-trans,poly-cis-dolichol + CTP


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA => (2E,19Z,22Z,25Z,28Z)-tetratriacontapentaenoyl-CoA + H2O


name: H(+) + heptanoyl-CoA + malonyl-[ACP] = 3-oxononanoyl-[ACP] + CO2 + CoA


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Drosophila melanogaster)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Mus musculus)


name: SMURF2 monoubiquitinates SMAD3 (Mus musculus)


name: UBA1 adenylates ubiquitin in the cytosol (Caenorhabditis elegans)


name: Neuropeptide S receptor binds neuropeptide S (Sus scrofa)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 9-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AMP + 2 H(+) + 2 phosphate => ATP + 2 H2O


name: L-glutamate(in) + N-acetyl-L-cysteine(out) => L-glutamate(out) + N-acetyl-L-cysteine(in)


name: H2O + L-glutamate + NAD(+) <=> 2-oxoglutarate + H(+) + NADH + NH4(+)


name: 9,9'-di-cis-zeta-carotene + 2 a quinone <=> 7,7',9,9'-tetra-cis-lycopene + 2 a quinol


name: Edg-2 lysophosphatidic acid receptor binding


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Plasmodium falciparum)


name: PGH2 is isomerised to PGD2 by HPGDS (Plasmodium falciparum)


name: TRAF1 is cleaved by caspases (Rattus norvegicus)


name: JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 (Homo sapiens)


name: WDR5 binds Me2sR3-replicative histone H3 (Mus musculus)


name: CTP + D-ribitol 5-phosphate + H(+) <=> CDP-L-ribitol + diphosphate


name: PPARA:RXRA binds Corepressors of PPARA (Mus musculus)


name: 2 3-(4-hydroxyphenyl)pyruvate + H(+) = (2S)-2-(4-hydoxybenzyl)-3-(4-hydroxyphenyl)-2-furonol carboxylate + H2O


name: citrate(out) + 4 Na(+)(out) => citrate(in) + 4 Na(+)(in)


name: VAV2 is a GEF for Rho/Rac family kinases (Gallus gallus)


name: Trimerization of TRAIL:TRAIL receptor complex (Rattus norvegicus)


name: PDGF dimer binds two receptors simultaneously (Canis familiaris)


name: 3 H(+)(in) + NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 H(+)(out) + NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: GLI2 is degraded by the proteasome (Homo sapiens)


name: F1Fo ATP synthase dimerizes (Drosophila melanogaster)


name: Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP (Rattus norvegicus)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Sus scrofa)


name: D-xylose(in) + H(+)(in) = D-xylose(out) + H(+)(out)


name: NF-kappa-B complex is transported from cytosol to nucleus (Canis familiaris)


name: CYP2E1 monooxygenates APAP to NAPQI (Gallus gallus)


name: H2O + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) = beta-D-mannose + N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B3)


name: "endoplasmic reticulum Man8GlcNAc2 1,2-alpha-mannosidase"


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate => etheroleate + H2O


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Sus scrofa)


name: Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Caenorhabditis elegans)


name: Syk activation leads to SLP-76 activation (Canis familiaris)


name: XIAP monoubiquinates TLE (Canis familiaris)


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Caenorhabditis elegans)


name: (indol-3-yl)acetate(out) + a dicarboxylate(in) <=> (indol-3-yl)acetate(in) + a dicarboxylate(out)


name: oxidoreductase activity, acting on CH or CH2 groups


name: ADRA2A,B,C bind ADR,NAd (Rattus norvegicus)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Schizosaccharomyces pombe)


name: Arachidonate is oxidised to 12R-HpETE by ALOX12B (Mus musculus)


name: ATP + erythritol = ADP + D-erythritol 1-phosphate + H(+)


name: "erythritol kinase (D-erythritol 1-phosphate-forming)"


name: GMP + methylglyoxal = N(2)-(1-hydroxy-2-oxopropyl)-GMP


name: Luteinizing hormone is a heterodimer (Rattus norvegicus)


name: H2O + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine => H(+) + N-hexadecanoylethanolamine + sn-glycerol 3-phosphate


name: CPT1A transfers PALM to CAR (Homo sapiens)


name: peptide-methionine (R)-S-oxide reductase activity


name: RNA Pol II initiates transcription from damaged DNA template (Drosophila melanogaster)


name: 3'-ketolactose + H2O => 3-keto-beta-D-galactose + beta-D-glucose


name: 3,6-anhydro-alpha-L-galactopyranose + H2O + NAD(+) = 3,6-anhydro-L-galactonate + 2 H(+) + NADH


name: (S)-lactate + 2 Fe(III)-[cytochrome c] <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + pyruvate


name: VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)


name: SUMOylation of EP300 with SUMO1 (Mus musculus)


name: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH => 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated


name: "With 2-oxoglutarate as one donor, and the other dehydrogenated"


name: (2E,6E)-farnesyl diphosphate = beta-sesquiphellandrene + diphosphate


name: 2 glutathione amide + H2O2 => glutathione amide disulfide + 2 H2O


name: H2O + indole-3-acetaldehyde + O2 => (indol-3-yl)acetate + H(+) + H2O2


name: Auto ubiqitination of TRAF6 bound to viral dsRNS:TLR3:TICAM1 complex (Homo sapiens)


name: 2',4,4',6'-tetrahydroxychalcone + UDP-alpha-D-glucose <=> 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + H(+) + UDP


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate


name: (2E,6E)-farnesyl diphosphate = beta-cadinene + diphosphate


name: 4-carboxy-3-methylbut-(2E)-enoyl-[ACP] + H(+) <=> 3-methylbut-(2E)-enoyl-[ACP] + CO2


name: benzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + toluene


name: ERBB3 binds neuregulins (Rattus norvegicus)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Homo sapiens)


name: Retrograde COPI vesicles bind kinesin and microtubules (Gallus gallus)


name: 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Mus musculus)


name: at-retinyl is hydrolysed from R* to release atRAL (Homo sapiens)


name: 2 AMP + 2 diphosphate + H(+) + polyporic acid => 2 3-phenylpyruvate + 2 ATP


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Mus musculus)


name: ATP + CoA + heptanedioate = 6-carboxyhexanoyl-CoA + AMP + diphosphate


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Drosophila melanogaster)


name: 1-hydroxy-2-naphthoate + O2 = (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H(+)


name: DGO binds to PK (Drosophila melanogaster)


name: Adenylate cyclase converts ATP into cyclic AMP (Canis familiaris)


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Canis familiaris)


name: (9Z,12Z)-octadecadienoyl-CoA + cholesterol = cholesteryl (9Z,12Z)-octadecadienoate + CoA


name: NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Gallus gallus)


name: L-homoserine + succinyl-CoA = CoA + O-succinyl-L-homoserine


name: 3,5-diiodo-L-tyrosine + H(+) + 2 NADPH => 2 iodide + L-tyrosine + 2 NADP(+)


name: a short-chain (3R)-hydroxy fatty acyl-CoA <=> a short-chain (2E)-enoyl-CoA + H2O


name: 12-hydroxyoctadecanoate + ATP + CoA = 12-hydroxyoctadecanoyl-CoA + AMP + diphosphate


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Gallus gallus)


name: Aquaporins passively transport glycerol out of cells (Caenorhabditis elegans)


name: [(1->4)-beta-D-mannosyl](n-1) + alpha-D-mannose 1-phosphate => [(1->4)-beta-D-mannosyl](n) + phosphate


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 2-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Rv1410c transports LprG:LM,LAM from cytosol to the cell wall (Homo sapiens)


name: an N-tetracosenoylsphinganine + CoA + H(+) => sphinganine + tetracosenoyl-CoA


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Drosophila melanogaster)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Mus musculus)


name: Phosphorylation of BRCA1-A complex at multiple sites by ATM (Sus scrofa)


name: acetyl-CoA + epi-neemfruitin B = 7-acetyl-epi-neemfruitin B + CoA


name: chelirubine + H2O2 => dihydrochelirubine + H(+) + O2


name: PLK3 phosphorylates TP53 (Rattus norvegicus)


name: MT-MMPs are sorted to the plasma membrane (Homo sapiens)


name: CTP + H(+) + N-methylethanolamine phosphate <=> CDP-N-methylethanolamine + diphosphate


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Canis familiaris)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Mus musculus)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Homo sapiens)


name: alpha-L-arabinopyanose + NADP(+) => H(+) + L-arabinono-1,4-lactone + NADPH


name: (1S,4S)-bornane-2,5-dione + FMNH2 + O2 <=> (1S,4S)-5-oxo-1,2-campholide + FMN + H(+) + H2O


name: FLIP(S) and procaspase-8 form heterodimer (Gallus gallus)


name: p-S276-RELA binds RELB (Canis familiaris)


name: FAR2 reduces PalmCoA to HXOL (Homo sapiens)


name: Capping complex formation (Drosophila melanogaster)


name: H(+) + kanamycin A + UDP => 2'-deamino-2'-hydroxyneamine + UDP-alpha-D-kanosamine


name: Displacement of TDG glycosylase by APEX1 at the AP site (Sus scrofa)


name: DOLPP1 dephosphorylates DOLDP to DOLP (Danio rerio)


name: (+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => (+)-artemisinate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: CTLH E3 ligase ubiquitinates LDHA (Mus musculus)


name: L-idonate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH


name: Phosphorylation of Platelet Sec-1 (Gallus gallus)


name: UV-DDB ubiquitinates XPC (Rattus norvegicus)


name: a 2-oxocarboxylate + H2O2 + NH4(+) => an L-alpha-amino acid + H2O + O2


name: RAB33B:GTP binds RIC1:RGP1 (Xenopus tropicalis)


name: GGPS1 hexamer transfers IPPP to DMAPP (Drosophila melanogaster)


name: "With a quinone or similar compound as acceptor"


name: (3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl-[ACP] + AH2 + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine <=> 6-[(3E,5E,7S)-5,7-dimethyl-2-oxonona-3,5-dienyl]-2,4-dihydroxy-3-methylbenzaldehyde + A + 4 CO2 + 4 CoA + H2O + holo-[ACP] + S-adenosyl-L-homocysteine


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: H(+) + N(1)-methyladenosine(1408) in 16S rRNA + S-adenosyl-L-homocysteine => adenosine(1408) in 16S rRNA + S-adenosyl-L-methionine


name: Activation of cytosolic AMPK by phosphorylation (Canis familiaris)


name: glyoxylate + H2O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> diphosphate + taxa-4,11-diene


name: LCAT:spherical HDL complex <=> LCAT + spherical HDL (Bos taurus)


name: Binding of TFIIIC to TFIIIA:Type I Promoter complex  (Rattus norvegicus)


name: MYSM1 deubiquitinates Histone H2A (Bos taurus)


name: a dicarboxylate(in) + xanthurenate(out) => a dicarboxylate(out) + xanthurenate(in)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O => H(+) + hexadecanoate + sn-glycerol 3-phosphocholine


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Bos taurus)


name: a ganglioside GD1a (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GD1a (d18:1(4E)) + H(+) + UDP


name: (5Z,8Z,11Z,14Z)-eicosatetraenamide + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + NH4(+)


name: Initial activation of proMMP2 by MMP1, 7 (Xenopus tropicalis)


name: 5-(3-carboxy-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+) => 7,8-dihydroxykynurenate + O2


name: ADP + H(+) + L-ribulose 5-phosphate => ATP + L-ribulose


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Xenopus tropicalis)


name: cGMP is degraded by PDEs (Drosophila melanogaster)


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Homo sapiens)


name: LTA4 is hydolysed to LTB4 by LTA4H (Homo sapiens)


name: OPLAH hydrolyses OPRO to L-Glu (Canis familiaris)


name: 1,4-dihydroxy-2-naphthoate + all-trans-heptaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-7 + CO2 + diphosphate


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Homo sapiens)


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Homo sapiens)


name: Luteinizing hormone receptor can bind LH (Bos taurus)


name: adenosine(2142) in 25S rRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methyladenosine(2142) in 25S rRNA + S-adenosyl-L-homocysteine


name: (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 = (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + di-(9Z)-octadecenoylglycerol


name: (S)-oxalosuccinate + H(+) => 2-oxoglutarate + CO2


name: (E)-sinapoyl-AMP + CoA => (E)-sinapoyl-CoA + AMP + H(+)


name: p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 (Rattus norvegicus)


name: NOX2 generates superoxide anion from oxygen (Mus musculus)


name: coenzyme M + methyl-Co(III)-[methylamine-specific corrinoid protein] = Co(I)-[methylamine-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: PC is converted to PS by PTDSS1 (Dictyostelium discoideum)


name: (1S,5S)-alpha-pinene + H(+) + NADH + O2 = alpha-pinene oxide + H2O + NAD(+)


name: Caspase-mediated cleavage of FADK 1 (Homo sapiens)


name: H(+) + N-tetracosanoyl-(4R)-hydroxysphinganine + NADPH + O2 = H2O + N-(2-hydroxytetracosanoyl)-(4R)-hydroxysphinganine + NADP(+)


name: LTA trimer binds TNFRSF1A,1B,14 (Bos taurus)


name: TBC1D3 associates with RAB5 (Gallus gallus)


name: (+)-artemisinic alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (+)-amorpha-4,11-diene + O2 + reduced [NADPH--hemoprotein reductase]


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate


name: Loss of SAR1B GTPase (Dictyostelium discoideum)


name: IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Rattus norvegicus)


name: methanophenazine + reduced coenzyme F420-(gamma-L-Glu)(n) <=> dihydromethanophenazine + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: AKT phosphorylates FOXO3 downstream of ESR1 and EGFR (Danio rerio)


name: Deamination at C6 position of adenosine in Editosome (ADAR2) (Homo sapiens)


name: (S)-coclaurine + S-adenosyl-L-methionine => (S)-N-methylcoclaurine + H(+) + S-adenosyl-L-homocysteine


name: 5,6-dihydrouridine(17) in tRNA + NADP(+) = H(+) + NADPH + uridine(17) in tRNA


name: but-3-en-2-one + H(+) + NADPH => butan-2-one + NADP(+)


name: glutarate(in) + kynurenate(out) <=> glutarate(out) + kynurenate(in)


name: (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => L-tyrosine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: P-type potassium:proton transporter activity


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Caenorhabditis elegans)


name: GRK1,4,7 phosphorylate MII to p-MII (Canis familiaris)


name: DHAP is converted to 1-acyl GO3P by GNPAT (Drosophila melanogaster)


name: (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + H2O => (3R)-hydroxy-(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA


name: (3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate + NADP(+) => 5alpha-dihydrotestosterone sulfate + H(+) + NADPH


name: 15-methylhexadecasphing-4-enine 1-phosphate + H2O => 15-methylhexadecasphing-4-enine + phosphate


name: template for synthesis of G-rich strand of telomere DNA activity


name: Activation of JAK kinases (Homo sapiens)


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Mus musculus)


name: Proteasome proteolyzes ub-HIF-alpha (Gallus gallus)


name: glutarate(in) + glycocholate(out) = glutarate(out) + glycocholate(in)


name: 1-O-[(E)-feruloyl]-beta-D-glucose + UDP => (E)-ferulate + UDP-alpha-D-glucose


name: ATG12 binds ATG7 dimer (Caenorhabditis elegans)


name: Translocation of PLC-gamma1 to PIP2 (Danio rerio)


name: all-trans-zeaxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> all-trans-antheraxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: dibenzothiophene 5-oxide + FMN + H(+) + H2O => dibenzothiophene + FMNH2 + O2


name: H2O + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a 1,2-diacyl-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)


name: protein tyrosine kinase collagen receptor activity


name: CDK4 inhibitors bind CDK4 (Drosophila melanogaster)


name: CTP(out) + ITP(in) => CTP(in) + ITP(out)


name: Activation of conventional Protein Kinase C (Gallus gallus)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Danio rerio)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene = 1,2,4-trichlorobenzene + chloride + H(+)


name: 1,6-dihydroxyphenazine N(5)-oxide + NADPH + O2 = 1,6-dihydroxyphenazine N(5),N(10)-dioxide + H2O + NADP(+)


name: (9Z)-octadecenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine => 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Mus musculus)


name: NPAS4 binds IQSEC3 gene promoter (Homo sapiens)


name: NADH + 2 oxidized [cytochrome P450] => H(+) + NAD(+) + 2 reduced [cytochrome P450]


name: Type II receptor phosphorylates type I receptor (Xenopus tropicalis)


name: H2O + 2 oxidized [4Fe-4S]-[ferredoxin] + taurine = aminoacetaldehyde + 3 H(+) + 2 reduced [4Fe-4S]-[ferredoxin] + sulfite


name: CYP2C19 5-hydroxylates omeprazole (Sus scrofa)


name: Translocation of active caspase-8 to the mitochondrial membrane (Canis familiaris)


name: Type B histone acetlytransferase complex acetylates histone H4 (Caenorhabditis elegans)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Caenorhabditis elegans)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Canis familiaris)


name: D-glyceraldehyde 3-phosphate + NAD(+) + phosphate => (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH


name: D-tryptophan + H2O + O2 <=> H2O2 + indole-3-pyruvate + NH4(+)


name: Interaction of Tie2 and Grb14 (Canis familiaris)


name: H2O2 + N-acetyl-D-galactosamino-1,5-lactone => N-acetyl-D-galactosamine + O2


name: H(+) + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + NADPH + O2 => 2 H2O + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADP(+)


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Danio rerio)


name: 3 Na(+)(out) + sulfate(out) => 3 Na(+)(in) + sulfate(in)


name: fructose 2,6-bisphosphate + H2O => fructose 6-phosphate + orthophosphate (Gallus gallus)


name: 2 H(+)(in) + H2 + menaquinone-8 <=> 2 H(+)(out) + menaquinol-8


name: (E)-4-hydroxyphenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-4-hydroxymandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)


name: CIT (citron kinase) binds activated RHOA, RHOB, RHOC and RAC1 (Homo sapiens)


name: depalmitoylated eNOS translocates from plasma membrane (Saccharomyces cerevisiae)