name: dodecanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4-hydroxy-6-(2-oxotridecyl)pyran-2-one + 3 CO2 + 4 CoA


name: (24S)-hydroxycholesterol + 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine <=> (24S)-24-hydroxycholesterol ester + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: GNRHR binds GNRHR peptide antagonists (Mus musculus)


name: ATP + cob(I)inamide-[corrinoid adenosyltransferase] => adenosylcob(III)inamide + apo-[corrinoid adenosyltransferase] + triphosphate


name: APBB1 and MAPK8 bind diphosphorylated H2AFX (Homo sapiens)


name: H2O + N-acetyl-L-glutamine => acetate + L-glutamine


name: 3xPPCDC:3FMN decarboxylates PPC (Homo sapiens)


name: quercetin + UDP-alpha-D-glucose = H(+) + quercetin 3-O-beta-D-glucoside + UDP


name: Demethylase KDM1A binds KLK2 and KLK3 promoters (Homo sapiens)


name: eburicol + O2 + reduced [NADPH--hemoprotein reductase] => 32-hydroxyeburicol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active ALK phosphorylates IRS1 (Homo sapiens)


name: GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Xenopus tropicalis)


name: Formation of the closed pre-initiation complex (Gallus gallus)


name: G-protein subunits dissociate from WNT:FZD complex (Bos taurus)


name: FLT3 ITD- and STAT5-dependent BCL2L1 gene expression (Homo sapiens)


name: LRRC16A binds F-actin capping protein (Rattus norvegicus)


name: (R)-carnitine + propanoyl-CoA <=> CoA + O-propanoyl-(R)-carnitine


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Homo sapiens)


name: (S)-1-pyrroline-5-carboxylate + H(+) + H2O => L-glutamate 5-semialdehyde


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: MAPK4,6 translocate to the cytoplasm (Rattus norvegicus)


name: chloride(out) + 2 hydrogencarbonate(in) + K(+)(in) => chloride(in) + 2 hydrogencarbonate(out) + K(+)(out)


name: BACE1 translocates from ER lumen to Golgi apparatus (Homo sapiens)


name: SOCS3 binds activated PTK6 (Danio rerio)


name: H2O + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] = beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-threonyl-[protein]


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Bos taurus)


name: Degradation of multiubiquitinated Nek2A (Bos taurus)


name: chloride(in) + D-leucine(in) + 2 Na(+)(in) => chloride(out) + D-leucine(out) + 2 Na(+)(out)


name: MTF1 dimer:12Zn2+ binds SNCB gene (beta-synuclein) (Homo sapiens)


name: mTORC1 phosphorylates AKT1S1 (Xenopus tropicalis)


name: tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate (Homo sapiens)


name: 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+) => L-dopa + O2


name: Polyubiquitinated RUNX3 translocates to the cytosol (Mus musculus)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Canis familiaris)


name: NFE2L2 dependent BCL2 expression (Homo sapiens)


name: H2O + N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein] => N(6)-(D-erythrulosyl)-L-lysyl-[protein] + phosphate


name: LTA trimer binds TNFRSF1A,1B,14 (Canis familiaris)


name: all-trans-13,14-dihydroretinoate + O2 + reduced [NADPH--hemoprotein reductase] => all-trans-4-hydroxy-13,14-dihydroretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Sus scrofa)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Bos taurus)


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Sus scrofa)


name: GSDMD oligomerizes into arc-, slit-shaped structures (Gallus gallus)


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + [thyroglobulin]-3-iodo-L-tyrosine + H2O2 <=> [thyroglobulin]-3,3',5-triiodo-L-thyronine + [thyroglobulin]-dehydroalanine + 2 H2O


name: GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a (Bos taurus)


name: ERBB2 KD mutants heterodimerize (Homo sapiens)


name: H2O + NADP(+) + pentanal = 2 H(+) + NADPH + pentanoate


name: L-seryl-[protein] + tetradecanoyl-CoA => CoA + O-tetradecanoyl-L-seryl-[protein]


name: JAK1 phosphorylates STAT3,STAT6 (Canis familiaris)


name: protein serine/threonine kinase activity


name: H(+) + NADH + 2 NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] => NAD(+) + 2 NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (S)-corytuberine + S-adenosyl-L-methionine <=> magnoflorine + S-adenosyl-L-homocysteine


name: EFNBs bind SDCBP (Drosophila melanogaster)


name: ILK interacts with beta-1 integrin (Homo sapiens)


name: 2 Fe(II)-[cytochrome c] + H(+) + nitroxyl + O2 <=> 2 Fe(III)-[cytochrome c] + H2O + nitrite


name: gamma-terpinene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + thymol


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Saccharomyces cerevisiae)


name: 4beta-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 4beta,7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: HTRA1 hydrolyzes ACAN (Aggrecan) (Sus scrofa)


name: TFAP2A,TFAP2C homodimers stimulate ESR1 gene expression (Homo sapiens)


name: D-allose + L-lysyl-[protein] = H2O + N(6)-(D-psicosyl)-L-lysyl-[protein]


name: NADPH + 2 oxidized [2Fe-2S]-[protein] => H(+) + NADP(+) + 2 reduced [2Fe-2S]-[protein]


name: p-STAT1:p-STAT4 translocates to the nucleus (Caenorhabditis elegans)


name: PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)


name: 3'-phosphoadenylyl sulfate + tauro-alpha-muricholate <=> adenosine 3',5'-bisphosphate + H(+) + tauro-alpha-muricholate 7-sulfate


name: HDAC6 deacetylates microtubules (Dictyostelium discoideum)


name: LIG1 binds POLB at long-patch BER site (Rattus norvegicus)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Bos taurus)


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Rattus norvegicus)


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Mus musculus)


name: [protein]-dithiol + NAD(+) => [protein]-disulfide + H(+) + NADH


name: 2 H(+) + malonyl-CoA + methylmalonyl-CoA + octadecanoyl-CoA <=> 4-hydroxy-5-methyl-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA


name: Transfer of ubiquitin from E1 to E2 (Xenopus tropicalis)


name: RAS:GTP binds RAL GDS proteins (Drosophila melanogaster)


name: ADP(out) + H(+)(out) + phosphate(in) = ADP(in) + H(+)(in) + phosphate(out)


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: Ferriheme dissociates from p-T-EIF2AK1:2xferriheme dimer (Homo sapiens)


name: Furin cleaves pro-factor IX to factor IX (Homo sapiens)


name: H2O + L-cysteine + O2 <=> 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)


name: Insertion of correct bases opposite the lesion by POLH (Bos taurus)


name: H(+) + L-methionyl-[F-actin] + NADPH + O2 => H2O + L-methionyl-(R)-S-oxide-[F-actin] + NADP(+)


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Bos taurus)


name: CDC42:GTP binds PAK2 (Rattus norvegicus)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Mus musculus)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP


name: a quinone + H2O + nitrite => a quinol + nitrate


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] = 3,17-didehydrostemmadenine + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NAD(+) + trans-cyclohexane-1,2-diol = 2-hydroxycyclohexan-1-one + H(+) + NADH


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycerol = 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: GRKs bind ADRB2:Catecholamine (Gallus gallus)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Drosophila melanogaster)


name: H(+) + N,N-dihydroxy-L-isoleucine => (1E,2S)-2-methylbutanal oxime + CO2 + H2O


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Rattus norvegicus)


name: chenodeoxycholate + lithocholoyl-CoA => chenodeoxycholoyl-CoA + lithocholate


name: 1-octadecanoyl 2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-[(9Z)-octadecenoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: acetyl-CoA + N-hydroxyputrescine => CoA + N(1)-acetyl-N(1)-hydroxyputrescine


name: PS is hydrolyzed to 1-acyl LPS by PLA2[15] (Caenorhabditis elegans)


name: dauca-4,7-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Sus scrofa)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: 3-fumarylpyruvate + H2O = fumarate + H(+) + pyruvate


name: SHC1 bound to IL2 receptor is phosphorylated (Rattus norvegicus)


name: 5 H(+) + L-pipecolate + malonyl-CoA + 3 NADPH => (1R,8aS)-octahydroindolizin-1-ol + CO2 + CoA + 2 H2O + 3 NADP(+)


name: HAGH hydrolyses (R)-S-LGSH to GSH and LACT (Saccharomyces cerevisiae)


name: LPL hydrolyses TGs from mature CMs (Sus scrofa)


name: 2 H(+) + 2 H2O + N(2)-succinyl-L-arginine = CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+)


name: [protein]-dithiol + [thioredoxin]-disulfide = [protein]-disulfide + [thioredoxin]-dithiol


name: allyl isothiocyanate + sulfate => (Z)-N-(sulfonatooxy)prop-2-enimidothioate


name: 1D-myo-inositol 3,4-bisphosphate + H2O <=> 1D-myo-inositol 3-phosphate + phosphate


name: linear maltodextrin => cyclomaltodextrin + H2O


name: EGF-TM7 receptors bind chondroitin sulphate (Canis familiaris)


name: Tyrosine kinase inhibitors bind to overexpressed FGFR2 variants (Homo sapiens)


name: 2-(dihydroxymethyl)-5-formylfuran + O2 => 2-carboxy-5-formylfuran + H(+) + H2O2


name: SUMOylation of RPA1 (RPA70) with SUMO2,3 (Xenopus tropicalis)


name: 7-epi-sesquithujene + diphosphate => (2E,6E)-farnesyl diphosphate


name: H2O + NAD(+) + propanal <=> 2 H(+) + NADH + propanoate


name: Activated type I receptor phosphorylates SMAD2/3 directly (Gallus gallus)


name: cytidine(34) in tRNA precursor + S-adenosyl-L-methionine = 5-methylcytidine(34) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: NLRX1 inhibits MAVS-DDX58 interaction (Homo sapiens)


name: NADP(+) + scytalone <=> H(+) + NADPH + naphthalene-1,3,6,8-tetrol


name: 3'-phosphoadenylyl sulfate + deoxycholate <=> 3alpha-sulfodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Bos taurus)


name: IRE1 binds IRE1 forming dimer (Xenopus tropicalis)


name: L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Association of LBP with LPS (Gallus gallus)


name: CO2 + propanoyl-CoA => (R)-methylmalonyl-CoA + H(+)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate <=> (1R,2R,3R)-prephytoene diphosphate + diphosphate


name: (9Z,12Z,15Z)-octadecatrienoate + H2O = (12Z,15Z)-10-hydroxyoctadecadienoate


name: p-S MAPKAPK5 phosphorylates HSPB1 (Sus scrofa)


name: JMJD1C demethylates H3K9 mono- and di-methylation (Drosophila melanogaster)


name: 2-hydroxyestrone + S-adenosyl-L-methionine => 2-hydroxy-3-methoxy-estrone + H(+) + S-adenosyl-L-homocysteine


name: PSMD9 binds PSMC3:PSMC6 (Dictyostelium discoideum)


name: (S)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH


name: RAC2 binds effectors at the plasma membrane (Dictyostelium discoideum)


name: (1R,2S,4R)-neodihydrocarveol + NAD(+) => (1R,4R)-dihydrocarvone + H(+) + NADH


name: ADP + H(+) + phosphate + uroporphyrin I(out) => ATP + H2O + uroporphyrin I(in)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Xenopus tropicalis)


name: 9S,10-epoxy-(10,12Z)-octadecadienoate + H(+) + L-aspartyl-[protein] <=> 9-O-10-oxo-(12Z)-octadecenoate L-aspartatyl ester-[protein]


name: ITPA hydrolyses dITP to dIMP (Sus scrofa)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Homo sapiens)


name: RNA Pol II initiates transcription from damaged DNA template (Caenorhabditis elegans)


name: STAT1 and STAT3 dimers translocate to the nucleus (Caenorhabditis elegans)


name: antimonite secondary active transmembrane transporter activity


name: CDCA5 (Sororin) enables cohesion of sister chromosomal arms (Canis familiaris)


name: MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants (Homo sapiens)


name: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] <=> all-trans-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: chorismate = 3-[(1-carboxyvinyl)-oxy]benzoate + H2O


name: D-arabinitol + NADP(+) = D-ribulose + H(+) + NADPH


name: 2-nitrobutanedioate + H2O + NADP(+) => (2S)-2-nitrosobutanedioate + H(+) + NADPH + O2


name: STAT binds to the active receptor (Xenopus tropicalis)


name: 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: H(+) + indican + UDP => indoxyl + UDP-alpha-D-glucose


name: I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Homo sapiens)


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Canis familiaris)


name: (E)-3-(indol-3-yl)acryloyl-CoA + (R)-3-(indol-3-yl)lactate => (E)-3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA


name: 17-(4-hydroxyphenyl)heptadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] <=> 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: dodecanoate + NH4(+) => dodecanamide + H2O


name: a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 (d18:1(4E)) + H(+) + UDP


name: guanosine(in) + Na(+)(in) => guanosine(out) + Na(+)(out)


name: ALPK1 phosphorylates TIFA (Canis familiaris)


name: (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate => (25R)-3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate + ATP + CoA


name: alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)


name: p-Y348-SYK dissociates (Xenopus tropicalis)


name: Sulfite is oxidized to sulfate (Dictyostelium discoideum)


name: 17alpha-estradiol + UDP-alpha-D-glucuronate <=> 17alpha-estradiol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: H(+) + N(alpha)-methyl-L-histidine + S-adenosyl-L-homocysteine => L-histidine + S-adenosyl-L-methionine


name: 5-amino-6-(D-ribitylamino)uracil + riboflavin => 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+)


name: 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) <=> CO2 + diphosphate + thiamine phosphate


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Danio rerio)


name: 1-hydroxy-6-methoxyphenazine + NADPH + O2 => 1-hydroxy-6-methoxyphenazine N(10)-oxide + H2O + NADP(+)


name: SGTA binds mislocalized membrane protein (Sus scrofa)


name: L-cysteine = 2-aminoprop-2-enoate + H(+) + hydrogen sulfide


name: Receptors CCR3, 4 and 5 bind CCL5 ligand (Rattus norvegicus)


name: NT5E:Zn2+ hydrolyses NAD+ (Xenopus tropicalis)


name: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate <=> H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ethanolamine + H(+)


name: NTP Binds Active Site of RNA Polymerase II (Xenopus tropicalis)


name: corticotropin-releasing hormone receptor 1 binding


name: SERPINA6 binds PREDL (Xenopus tropicalis)


name: an N(7)-methylguanosine in 18S rRNA + S-adenosyl-L-homocysteine => a guanosine in 18S rRNA + S-adenosyl-L-methionine


name: (9Z)-octadecenoyl-CoA + octadecan-1-ol => 1-O-octadecyl (9Z)-octadecenoate + CoA


name: 15-cis-phytoene + 2 A => 2 AH2 + all-trans-zeta-carotene


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) (Mus musculus)


name: Activation of Talin (Drosophila melanogaster)


name: (R)-benzoin + NADP(+) = benzil + H(+) + NADPH


name: "benzil reductase [(R)-benzoin forming]"


name: imidazol-4-one + NH4(+) => 4-aminoimidazole + H(+) + H2O


name: 4-coumaroyl-CoA + H(+) + malonyl-CoA <=> (4-coumaroyl)acetyl-CoA + CO2 + CoA


name: Activated NOD1 oligomerizes (Dictyostelium discoideum)


name: estradiol 17-beta-dehydrogenase [NAD(P)+] activity


name: SEC4C,D bind GOSR2 and STX5 (Plasmodium falciparum)


name: protein kinase A catalytic subunit binding


name: Ubiquitinated geminin is degraded by the proteasome (Danio rerio)


name: Caspase-mediated cleavage of occludin (Mus musculus)


name: hexadecanoyl-CoA + octan-1-ol = CoA + octyl hexadecanoyl


name: beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphoenolpyruvate <=> 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphate


name: catechol + O2 <=> cis,cis-muconate + 2 H(+)


name: a triacyl-sn-glycerol + H2O = a 2,3-diacyl-sn-glycerol + a fatty acid + H(+)


name: (2E,6E)-farnesyl diphosphate = (Z)-beta-farnesene + diphosphate


name: AMP + ATP <=> ADP + ADP [AK2] (Schizosaccharomyces pombe)


name: an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Danio rerio)


name: alpha-D-galactose 1-phosphate + 2 H(+) + UMP => H2O + UDP-alpha-D-glucose


name: (+)-vincadifformine + acetate + NADP(+) => dihydroprecondylocarpine acetate + NADPH


name: LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + tauro-alpha-muricholate => adenosine 3',5'-bisphosphate + H(+) + tauro-alpha-muricholate 7-sulfate


name: dihydrosanguinarine + NAD(+) <=> NADH + sanguinarine


name: 4 H(+) + luteothin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> aureothin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: Epsin family proteins bind ubiquitinated cargo (Gallus gallus)


name: H2O + N(omega)-hydroxy-L-arginine + NADP(+) => H(+) + L-arginine + NADPH + O2


name: HMGB1 release from cells (Plasmodium falciparum)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 1-O-acyl-N-(acetyl)-sphing-4-enine + 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + octanoyl-CoA => 1-O-hexadecyl-2-acetyl-3-octanoyl-sn-glycerol + CoA


name: H(+)(in) + L-rhamnopyranose(in) = H(+)(out) + L-rhamnopyranose(out)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Rattus norvegicus)


name: AKR1C3 reduces atRAL to atROL (Schizosaccharomyces pombe)


name: 2 L-ascorbate + N-(9Z,12Z,15Z)-octadecatrienoylglycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine


name: LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Xenopus tropicalis)


name: beta-D-Gal-(1<->1')-Cer + UDP-alpha-D-galactose = alpha-D-Gal-(1->4)-beta-D-Gal-(1<->1')-Cer + H(+) + UDP


name: L-tetrahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> (E)-7-(methylsulfanyl)heptanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Hydrolysis of PIP2 by PLCG (Rattus norvegicus)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Dictyostelium discoideum)


name: PRKCZ recruits RAS in response to estrogen stimulation (Drosophila melanogaster)


name: RHOF binds effectors at the plasma membrane (Drosophila melanogaster)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + NADP(+) <=> 1-(9Z)-octadecenoylglycerone 3-phosphate + H(+) + NADPH


name: CMP + ganglioside GT1a alpha + H(+) => a ganglioside GD1alpha + CMP-N-acetyl-beta-neuraminate


name: UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out) = UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in)


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: STAB2 (FEEL-2) binds ligands (Bos taurus)


name: cyclohexanol + NAD(+) <=> cyclohexanone + H(+) + NADH


name: p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Drosophila melanogaster)


name: Ub-RibC-AXIN is degraded by the proteasome (Sus scrofa)


name: acetate + tryptamine => H2O + N-acetyltryptamine


name: PIP3 recruits PDK1 and AKT to the membrane (Caenorhabditis elegans)


name: DNA polymerase epsilon binds at the origin (Gallus gallus)


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: AKT phosphorylates MKRN1 (Schizosaccharomyces pombe)


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Mus musculus)


name: asnovolin K + S-adenosyl-L-homocysteine => asnovolin I + S-adenosyl-L-methionine


name: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity


name: CLCN4/5/6 exchange Cl- for H+ (Mus musculus)


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine => 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester


name: FMN + formaldehyde + 2 H(+) + H2O + methanesulfinate => dimethyl sulfone + FMNH2 + O2


name: SARS-CoV-1 nsp3 deubiquinates K48-linked pUb IkBA (Homo sapiens)


name: SUMOylation of DNMT3B with SUMO1 (Rattus norvegicus)


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Xenopus tropicalis)


name: 9alpha-copalyl diphosphate + H2O => (13S)-vitexifolin A + diphosphate


name: DHCR24 reduces ZYMOL to ZYMSTNL (Mus musculus)


name: 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + typhasterol => 6-deoxotyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: 4-phospho-D-erythronate + NAD(+) => (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + H(+) + NADH


name: UCHL1, UCHL3 cleave ubiquitin adducts (Rattus norvegicus)


name: S-adenosyl-L-methionine + serotonin => 5-methoxytryptamine + H(+) + S-adenosyl-L-homocysteine


name: delphinidin + UDP-alpha-D-galactose => delphinidin 3-O-beta-D-galactoside + H(+) + UDP


name: H2O + mycophenolic acid O-acyl-beta-D-glucuronide <=> D-glucuronate + H(+) + mycophenolate


name: Disassociation of CLIP from MHC II (Homo sapiens)


name: Assembly of IFT B complex (Homo sapiens)


name: Phosphorylation of SLP-76 (Homo sapiens)


name: beta-D-glucose + luteolin => H2O + luteolin 4'-O-beta-D-glucoside


name: hexadecane-1,16-diol + O2 => H2O2 + hydroxyhexadecanal


name: N(6)-carboxybiotinyl-L-lysyl-[protein] + propanoyl-CoA => methylmalonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]


name: PAK1 phosphorylates myosin phosphatase (Canis familiaris)


name: RAR:RXR binds SUMO-CRABP2:atRA (Danio rerio)


name: 5-deoxystrigol + H2O => 5-deoxystrigol ABC-rings + 5-hydroxy-3-methylfuran-2(5H)-one


name: ALOX15 oxidises DHA to 17(S)-Hp-DHA (Bos taurus)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Xenopus tropicalis)


name: NGF homodimer binds to p75NTR (Canis familiaris)


name: (E)-caffeoyl-CoA + S-adenosyl-L-methionine <=> (E)-feruloyl-CoA + H(+) + S-adenosyl-L-homocysteine


name: 24,25-dihydrolanosterol + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] => 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Homo sapiens)


name: 1-O-alkyl-2-acyl-sn-glycerol + ATP = 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: ATP + O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein] <=> diphosphate + O-[5'-(adenylyl-(5'->3')-adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein]


name: Phosphorylated ETS1 binds p16INK4A promoter (Homo sapiens)


name: (10bR,4aS)-noroxomaritidine + H(+) + NADPH <=> (10bR,4aS)-oxomaritidine + NADP(+)


name: SRC-1 binds p-Y397-PTK2 (Canis familiaris)


name: SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Mus musculus)


name: 2,3,5,6-tetrachloro-1,4-benzoquinone + NADH => 2,3,5,6-tetrachlorohydroquinone + H(+) + NAD(+)


name: PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Canis familiaris)


name: HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Rattus norvegicus)


name: 7-oxoglycolithocholate + H(+) + NADH => glycochenodeoxycholate + NAD(+)


name: An unknown protease degrades hCBXs (Homo sapiens)


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Caenorhabditis elegans)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + (S)-mandelate + O2 <=> (6R)-L-erythro-6,7-dihydrobiopterin + (S)-4-hydroxymandelate + H2O


name: acetoacetate(out) + H(+)(out) = acetoacetate(in) + H(+)(in)


name: CBL ubiquitinates Sprouty (Drosophila melanogaster)


name: PP6 dephosphorylates SEC24 (Xenopus tropicalis)


name: 17alpha-estradiol + UDP-alpha-D-glucuronate <=> 17alpha-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)


name: ADP + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate => ATP + N-acetyl-D-glucosamine


name: a ganglioside Ac-O-8-GD2 = a ganglioside Ac-O-9-GD2


name: Dehalogenation of carbon tetrachloride to form a free radical (Dictyostelium discoideum)


name: ADO oxidises 2AET to HTAU (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 9-hydroperoxy-(5Z,7E,11Z,14Z)-eicosatetraenoate


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 (Mus musculus)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Homo sapiens)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] = 16alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-demethylmenaquinol-11 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-undecaprenyl diphosphate + H(+)


name: COASY phosphorylates DP-CoA (Homo sapiens)


name: SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: Phosphorylation of USP8 by P-AKT (Mus musculus)


name: D-glucose(out) + Na(+)(out) = D-glucose(in) + Na(+)(in)


name: (3-chloro-2,4,6-trihydroxyphenyl)hexan-1-one + chloride + FADH2 + O2 <=> (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + FAD + 2 H2O


name: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Canis familiaris)


name: GNAT3 exchanges GDP for GTP in TAS1R2:TAS1R3:sweet compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)


name: 1,4-dihydroxy-6-naphthoate + all-trans-octaprenyl diphosphate + H(+) => 2-demethylmenaquinol-8 + CO2 + diphosphate


name: 7,8-dihydromethanopterin + H(+) + NADH => 5,6,7,8-tetrahydromethanopterin + NAD(+)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Rattus norvegicus)


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Gallus gallus)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Saccharomyces cerevisiae)


name: a pseudouridine in rRNA + S-adenosyl-L-methionine = an N(1)-methylpseudouridine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Danio rerio)


name: TMPRSS2 Mediated SARS-CoV-2 Spike Protein Cleavage and Endocytosis (Homo sapiens)


name: p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + 1-hexadecanoylglycerone 3-phosphate <=> 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate


name: 1-docosanoylglycerol + H2O => docosanoate + glycerol + H(+)


name: SLC24A1 exchanges 4Na+ for Ca2+, K+ (Homo sapiens)


name: (5R,12R,14S)-dolasta-1(15),8-diene + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: SLCO2B1 has a narrow substrate specificity (Sus scrofa)


name: (R)-2-methylpyrrolidine + NADP(+) => 2-methyl-1-pyrroline + H(+) + NADPH


name: a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a monoacyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol


name: Alpha-1-Microglobulin is cleaved (Sus scrofa)


name: IRAK1 induces oligomerisation of TRAF6 (Canis familiaris)


name: nsp12 misincorporates a nucleotide in nascent RNA minus strand (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + sn-glycerol 3-phosphate <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: KAT5 acetylates ATM at DNA DSBs (Bos taurus)


name: ZFP36 (TTP) recruits RNA degradation activities (Homo sapiens)


name: dihydrophloroglucinol + NADP(+) <=> 1,3,5-trihydroxybenzene + NADPH


name: 1-deoxy-11-oxopentalenate + H(+) + NADPH + O2 => H2O + NADP(+) + neopentalenolactone D


name: Neuropeptide S receptor binds neuropeptide S (Rattus norvegicus)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA


name: ADP-L-glycero-beta-D-manno-heptose + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-[alpha-D-Gal-(1->6)]-alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-4-O-PO3(2-)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A => ADP + H(+) + lipid A-core


name: A + cyclohexanone = AH2 + cyclohex-2-enone


name: Activated FGFR1 binds FRS3 (Mus musculus)


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Canis familiaris)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 2-hydroxytestosterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (3S)-3-hydroxydodecanoyl-CoA => (2E)-dodecenoyl-CoA + H2O


name: FeHM dissociates from MetHb (Canis familiaris)


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) = H(+) + NADPH + testosterone


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Caenorhabditis elegans)


name: AMP + diphosphate + OPC-6-CoA => ATP + CoA + OPC-6


name: H2O + N-hexanoyl-sphinganine <=> hexanoate + sphinganine


name: Interaction of IQGAP1 with nephrin (Danio rerio)


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Drosophila melanogaster)


name: Binding of SHC1 to p-5Y-EGFRvIII (Homo sapiens)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-oxononanoate + H(+)


name: Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Bos taurus)


name: IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Canis familiaris)


name: histone H2AK119 ubiquitin ligase activity


name: DHF is reduced to tetrahydrofolate (THF) (Saccharomyces cerevisiae)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP


name: (15S)-hydroperoxy-(11Z,13E)-eicosadienoate + 2 glutathione = (15S)-hydroxy-(11Z,13E)-eicosadienoate + glutathione disulfide + H2O


name: Phosphorylation of the Emi1 DSGxxS degron by Plk1 (Rattus norvegicus)


name: L-glutamine + pyruvate <=> 2-oxoglutaramate + L-alanine


name: Factor IIa inhibitors (compounds) binds IIa (Gallus gallus)


name: ATP + gamma-L-glutamyl-(2S)-2-aminobutanoate + glycine => ADP + H(+) + ophthalmate + phosphate


name: CPT1B transfers PALM to CAR (Sus scrofa)


name: 3-(4-hydroxyphenyl)pyruvate + dimethylallyl diphosphate => 3-dimethylallyl-4-hydroxyphenylpyruvate + diphosphate


name: 2 Fe(II)-[cytochrome b5] + H(+) + NADP(+) => 2 Fe(III)-[cytochrome b5] + NADPH


name: (8Z,11Z)-5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine => (8Z,11Z)-5-(pentadeca- 8,11,14-trien-1-yl)resorcinol-3-methyl ether + H(+) + S-adenosyl-L-homocysteine


name: Activation of Rap1 by membrane-associated GEFs (Sus scrofa)


name: Loading of PCNA - Sliding Clamp Formation (Homo sapiens)


name: [fructose-bisphosphate aldolase]-L-lysine + 3 S-adenosyl-L-methionine => [fructose-bisphosphate aldolase]-N(6),N(6),N(6)-trimethyl-L-lysine + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: GBF1 stimulates nucleotide exchange on ARF (Schizosaccharomyces pombe)


name: H(+) + indole-3-acetaldehyde + NADH => indole-3-ethanol + NAD(+)


name: activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the  phospho-IkB (Gallus gallus)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Bos taurus)


name: [pyruvate, water dikinase]-phosphate + H(+) + phosphate = [pyruvate, water dikinase] + diphosphate


name: "([Pyruvate, water dikinase] phosphate) phosphotransferase"


name: (E)-4-coumarate + ATP + H(+) => (E)-4-coumaroyl-AMP + diphosphate


name: ALDH7A1 oxidises BETALD to BET (Caenorhabditis elegans)


name: Delta(6)-protoilludene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants (Homo sapiens)


name: An unknown oxidase oxidises D-UBGN to UBN (Homo sapiens)


name: [amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ATP <=> [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + ADP


name: [collagen]-(5R)-5-hydroxy-L-lysyl-N-S-L-methionyl-[collagen] + H(+) + 2 H2O => (5R)-5-hydroxy-L-lysyl-[collagen] + H2O2 + L-methionyl-[collagen]


name: alpha-D-glucose 6-phosphate + O-phospho-L-seryl-[protein] => alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]


name: a 3-oxo-fatty acyl-CoA + H(+) + NADPH = a 3-hydroxy-fatty acyl-CoA + NADP(+)


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Mus musculus)


name: (R)-lactaldehyde + NAD(+) => H(+) + methylglyoxal + NADH


name: H(+) + hexadecanoate + NADPH + O2 <=> 14-hydroxyhexadecanoate + H2O + NADP(+)


name: RHOF GAPs stimulate RHOF GTPase activity (Caenorhabditis elegans)


name: 6-phospho-D-gluconate + NADP(+) => CO2 + D-ribulose 5-phosphate + NADPH


name: sulfate uptake in the cytosol (Mycobacterium tuberculosis)


name: p-S MAPK6 phosphorylates NCOA3 (Xenopus tropicalis)


name: L1-EGFR trans-heterodimerization (Rattus norvegicus)


name: AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn) => ATP + L-asparagine + tRNA(Asn)


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Rattus norvegicus)


name: N,N'-diacetylchitobiose + O2 => H2O2 + N,N'-diacetylchitobiono-1,5-lactone


name: alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity


name: ALOX5 oxidises DHA to 7-HDHA (Sus scrofa)


name: Loading of claspin onto DNA during replication origin firing (Gallus gallus)


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)


name: NADP(+) + taurochenodeoxycholate => 7-oxotaurolithocholate + H(+) + NADPH


name: (E)-sinapate + UDP-alpha-D-glucose <=> 4-O-(beta-D-glucosyl)-trans-sinapate + H(+) + UDP


name: SLC44A1 transports Cho from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: CDC42 GEFs activate CDC42 (Dictyostelium discoideum)


name: Formation of alternative pathway C5 convertase (Xenopus tropicalis)


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Bos taurus)


name: PIAS1,3 SUMOylates NR5A1 with SUMO2 (Gallus gallus)


name: H2O + N(2)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2 <=> (1-deoxy-D-fructos-1-yl)amine + 6-amino-2-oxohexanoate + H2O2


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP


name: PRKACA phosphorylates TNNI3 (Drosophila melanogaster)


name: 4beta-carboxyl motiol + O2 + reduced [NADPH--hemoprotein reductase] = 2alpha-hydroxyl, 4beta-carboxyl motiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-phenyl-1,2-propanedione + H(+) + NADH => (S)-phenylacetylcarbinol + NAD(+)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Mus musculus)


name: LDL + LDLR => LDL:LDLR complex (Bos taurus)


name: 2 5,6-dihydroxyindole + O2 = 2 H2O + 2 indole-5,6-quinone


name: PRKCZ recruits RAS in response to estrogen stimulation (Canis familiaris)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Canis familiaris)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Plasmodium falciparum)


name: CTP + H(+) + N(5)-phospho-L-glutamine = diphosphate + N(5)-(cytidine 5'-diphosphoramidyl)-L-glutamine


name: (6S)-5,6,7,8-tetrahydrofolate + glycine + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + CO2 + NADH + NH4(+)


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA1 (d18:1(4E)/18:0) = CMP + ganglioside GM1 (d18:1(4E)/18:0) + H(+)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Caenorhabditis elegans)


name: L-threonine + NAD(+) => aminoacetone + CO2 + NADH


name: ARL1 recruits TGN Golgin homodimers (Rattus norvegicus)


name: (2E,9Z)-hexadecadienoyl-[ACP] + H(+) + NADH => (9Z)-hexadecenoyl-[ACP] + NAD(+)


name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol (Saccharomyces cerevisiae)


name: (E)-hexadec-2-enoate + ATP + CoA = (2E)-hexadecenoyl-CoA + AMP + diphosphate


name: prunetin + UDP-alpha-D-glucuronate <=> H(+) + prunetin-C(8)-beta-D-glucuronide + UDP


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Danio rerio)


name: RAF phosphorylates MAP2K dimer (Rattus norvegicus)


name: Persulfide sulfur is dioxygenated (Mus musculus)


name: beta-D-fructose 2,6-bisphosphate + H2O => beta-D-fructose 2-phosphate + phosphate


name: pseudouridine(1248) in human 18S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methylpseudouridine(1248) in human 18S rRNA + S-adenosyl-L-homocysteine


name: 4,5-dihydroxyphthalate + H(+) + NADH => cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+)


name: ABCC1 transports cytosolic RCbl to extracellular region (Canis familiaris)


name: G6PC hydrolyzes G6P to Glc and Pi (liver) (Homo sapiens)


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine


name: 3'-phosphoadenylyl sulfate + firefly L-luciferin => adenosine 3',5'-bisphosphate + firefly L-sulfoluciferin + H(+)


name: 2-oxopropyl-coenzyme M + CO2 + NADPH => acetoacetate + coenzyme M + NADP(+)


name: 1D-myo-inositol 2-phosphate + phosphate => 1D-myo-inositol 2,5-bisphosphate + H2O


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H(+) + malonyl-CoA => 3-oxo-(10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + CO2 + CoA


name: Syndecans 1, 2 & 4 bind VTN (Sus scrofa)


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Caenorhabditis elegans)


name: 3-aminobutanoate + pyruvate <=> acetoacetate + L-alanine


name: 3-deacetyl-3-vinylbacteriochlorophyllide a + H2O => 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a


name: (9Z)-17-hydroxyoctadec-9-enoate 17-O-sophoroside + H(+) + UDP => (9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + UDP-alpha-D-glucose


name: dATP + H2O = 2'-deoxyadenosine + H(+) + triphosphate


name: acetyl-CoA + N-terminal glycyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetylglycyl-[protein]


name: diphosphate + holo-[malonate decarboxylase ACP] => 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + apo-[malonate decarboxylase ACP]


name: kaempferol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => 2 H(+) + 2 H2O + myricetin + 2 oxidized [NADPH--hemoprotein reductase]


name: ADP + H(+) + psilocybin => ATP + psilocin


name: 3-oxohexadecasphinganine + H(+) + NADPH => hexadecasphinganine + NADP(+)


name: MTMR6 binds MTMR9 (Saccharomyces cerevisiae)


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Homo sapiens)


name: SERPINC1 binds SERPINC1 activators (Danio rerio)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + O2 => (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E)-docosapentaenoate


name: AKT phosphorylates MKRN1 (Caenorhabditis elegans)


name: 1-hexadecanoylglycerone 3-phosphate + octadecan-1-ol <=> 1-O-octadecylglycerone 3-phosphate + H(+) + hexadecanoate


name: AMOT proteins bind WWTR1 (TAZ) (Xenopus tropicalis)


name: 1,2-dinitroglycerol + NADP(+) + nitrite => NADPH + nitroglycerin


name: 3-phenylpropanoate + NAD(+) = (E)-cinnamate + H(+) + NADH


name: Formation of Cyclin A:Cdc2 complexes (Xenopus tropicalis)


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + AH2 + O2 <=> (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + A + 2 H2O


name: misfolded CFTR is degraded by the 26S proteasome (Dictyostelium discoideum)


name: Association of Cks1 with SCF(Skp2) complex (Homo sapiens)


name: Exocytosis of Proactivator polypeptide (Canis familiaris)


name: 3-dehydro-D-glucose 6-phosphate + L-glutamate => 2-oxoglutarate + D-kanosamine 6-phosphate


name: benzylamine + pyruvate = benzaldehyde + L-alanine


name: NADP(+) + pyridine 3-methanol => H(+) + NADPH + pyridine-3-carbaldehyde


name: NADP(+) + prostaglandin F2alpha = H(+) + NADPH + prostaglandin H2


name: a mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+) => an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Bos taurus)


name: LYPLA2 hydrolyses PALM-C3,4-GAP43 (Homo sapiens)


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Danio rerio)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: A + cis-4-hydroxy-D-proline = 4-hydroxy-1-pyrroline-2-carboxylate + AH2 + H(+)


name: 1-hydroxy-6-methoxyphenazine + S-adenosyl-L-methionine = 1,6-dimethoxyphenazine + H(+) + S-adenosyl-L-homocysteine


name: STUB1 (CHIP) ubiquitinates SMAD3 (Rattus norvegicus)


name: RAN stimulates fusion of nuclear envelope (NE) membranes (Rattus norvegicus)


name: (3S)-hydroxyeicosanoyl-CoA + NAD(+) = 3-oxoeicosanoyl-CoA + H(+) + NADH


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Dictyostelium discoideum)


name: CFTR transits to the plasma membrane (Drosophila melanogaster)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Caenorhabditis elegans)


name: AJUBA binds centrosome-associated AURKA (Xenopus tropicalis)


name: Gbeta:gamma recruits PI3K gamma (Bos taurus)


name: an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 2 Fe(III)-[cytochrome b5] + H2O + N-acyl-4-hydroxyeicosasphinganine


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: L-arginine + L-cysteinyl-[NO transferase protein] + NADPH + 2 O2 = 2 H2O + L-citrulline + NADP(+) + S-nitroso-L-cysteinyl-[NO transferase protein]


name: L-threonine + uridine-5'-aldehyde => (5'S,6'S)-C-glycyluridine + acetaldehyde


name: D-cellotetraono-1,5-lactone + H2O => D-cellotetraonate + H(+)


name: CALCR binds erenumab (Drosophila melanogaster)


name: 5,10-methylenetetrahydromethanopterin + H2O => 5,6,7,8-tetrahydromethanopterin + formaldehyde


name: (4R,5R)-4,5-dihydroxycyclohex-2-ene-1-carbonyl-CoA + NADP(+) => (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene-1-carbonyl-CoA + H(+) + NADPH


name: Cleavage of Procaspase-3 by the apoptosome (Sus scrofa)


name: D-galactaro-1,4-lactone => 5-dehydro-4-deoxy-D-glucarate + H(+)


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Mus musculus)


name: IRAK1 gene expression is inhibited by MECP2 (Homo sapiens)


name: fumitremorgin C + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 12alpha,13alpha-dihydroxyfumitremorgin C + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: ATP + holo-[CmaA peptidyl-carrier protein] + L-alloisoleucine <=> AMP + diphosphate + L-alloisoleucyl-[CmaA peptidyl-carrier protein]


name: S-adenosyl-L-methionine + uridine in 25S rRNA => H(+) + N(3)-methyluridine in 25S rRNA + S-adenosyl-L-homocysteine


name: H(+)(in) + L-glutamine(out) + Na(+)(out) => H(+)(out) + L-glutamine(in) + Na(+)(in)


name: 3-oxoeicosanoyl-CoA + H(+) + NADPH => (3R)-hydroxyeicosanoyl-CoA + NADP(+)


name: HEY1 gene expression is positively regulated by NOTCH3 and STAT1 (Homo sapiens)


name: "protein geranylgeranyltransferase type II"


name: (12R)-hydroxy-(9Z)-octadecenoyl-CoA + 1,2-di-(12R-hydroxy-9Z-octadecenoyl)-sn-glycerol <=> 1,2,3-tri-(12R-hydroxy-9Z-octadecenoyl)-glycerol + CoA


name: USP28 deubiquitinates CLSPN and MYC (Mus musculus)


name: 3-oxotetradecanedioyl-CoA + H(+) + NADH => (3S)-hydroxytetradecanedioyl-CoA + NAD(+)


name: GDP-beta-L-fucose + L-threonyl-[EGF-like domain protein] = 3-O-(alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + GDP + H(+)


name: (E)-sinapaldehyde + CoA + NADP(+) <=> (E)-sinapoyl-CoA + H(+) + NADPH


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Canis familiaris)


name: WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Caenorhabditis elegans)


name: 3,4-dihydroxybenzoate + O2 => 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)


name: acetaldehyde + dopamine <=> (R)-salsolinol + H2O


name: H2O + L-saccharopine + NADP(+) => (S)-2-amino-6-oxohexanoate + H(+) + L-glutamate + NADPH


name: TPMT transfers methyl group to 6MP, forming 6MeMP (Homo sapiens)


name: Formation of Pol zeta complex (Schizosaccharomyces pombe)


name: a disubstituted aliphatic (S)-hydroxynitrile => a ketone + hydrogen cyanide


name: TRAF1 is cleaved by caspases (Bos taurus)


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Plasmodium falciparum)


name: H(+) + hexacosanoyl-CoA + malonyl-CoA = 3-oxooctacosanyol-CoA + CO2 + CoA


name: H2O + N(5)-[1(S)-1-carboxyethyl]-L-ornithine + NADP(+) <=> H(+) + L-ornithine + NADPH + pyruvate


name: 3-O-acetylpapaveroxine + H2O <=> acetate + H(+) + narcotine hemiacetal


name: histone H3K9 trimethyltransferase activity


name: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O => 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+)


name: Hv1 Mediated H+ Permeability (Rattus norvegicus)


name: 7beta-hydroxycholesterol(out) + ADP + H(+) + phosphate => 7beta-hydroxycholesterol(in) + ATP + H2O


name: Binding of Cleavage factors and Poly(A)Polymerase to the CstF:CPSF:Pre-mRNA Complex (Mus musculus)


name: (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + AH2 + O2 <=> (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + A + 2 H2O


name: 3'-phosphoadenylyl sulfate + alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol => 6-sulfo-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol + adenosine 3',5'-bisphosphate + H(+)


name: H2O + N-dodecanoyl-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + dodecanoate


name: PRKAA2 phosphorylates nuclear NFE2L2 (Homo sapiens)


name: Association of procollagen type XIII (Homo sapiens)


name: Formation of FACT complex (Caenorhabditis elegans)


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Canis familiaris)


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)


name: Association of DFF with alpha:beta importin (Rattus norvegicus)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Gallus gallus)


name: MAPK1 phosphorylates SOX10 (Drosophila melanogaster)


name: Initial activation of proMMP13 by MMP3 (Rattus norvegicus)


name: SLC45A3 transports Glc from extracellular region to cytosol (Canis familiaris)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Mus musculus)


name: (3S)-hydroxyoctadecanoyl-CoA <=> (2E)-octadecenoyl-CoA + H2O


name: H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein] = N(6)-(D-fructosyl)-L-lysyl-[protein] + phosphate


name: 2-oxoglutarate + 3-(N-acetyl-N-hydroxy)aminopropylphosphonate + O2 = (R)-(3-(acetylhydroxyamino)-2-hydroxypropyl)phosphonate + CO2 + succinate


name: cytidine(out) + 2 Na(+)(out) => cytidine(in) + 2 Na(+)(in)


name: Formation of N-glucuronides (Sus scrofa)


name: L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose => alpha-D-glucosyl-L-tyrosyl-[glycogenin] + H(+) + UDP


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)


name: chloride(out) + D-serine(out) + 2 Na(+)(out) <=> chloride(in) + D-serine(in) + 2 Na(+)(in)


name: NADH + nitroglycerin => 1,2-dinitroglycerol + NAD(+) + nitrite


name: 3-methylbutanoyl-CoA + S-adenosyl-L-methionine = CoA + H(+) + N-isovaleryl-L-homoserine lactone + S-methyl-5'-thioadenosine


name: dihydro-ML-236C-[compactin nonaketide synthase] + H2O = dihydro-ML-236C carboxylate + H(+) + holo-[compactin nonaketide synthase]


name: geranylgeranyl diphosphate + H2O = (13E)-labda-7,13-dien-15-ol + diphosphate


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-pyrethrolone => CoA + pyrethrin II


name: ATP + H2O + indoxyl sulfate(in) => ADP + H(+) + indoxyl sulfate(out) + phosphate


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose = beta-D-Gal-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: (E)-4-coumaroyl-AMP + CoA <=> (E)-4-coumaroyl-CoA + AMP + H(+)


name: NLK translocates to nucleus (Sus scrofa)


name: NSF and SNAPs bind cis-SNARE complex (Plasmodium falciparum)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Caenorhabditis elegans)


name: PGH2 is degraded to 12S-HHT and MDA by TBXAS1 (Rattus norvegicus)


name: RDH11 reduces RBP2:atRAL to RBP2:atROL (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N-(5,6-epoxy-8Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: Collagen type III degradation by MMP14 (Canis familiaris)


name: a 5'-end triphospho-guanosine-ribonucleotide-snRNA + CO2 + formaldehyde + H(+) + succinate => 2-oxoglutarate + a 5'-end methyltriphosphate-guanosine-ribonucleotide-snRNA + O2


name: 1-heptadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA <=> 1-heptadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Rattus norvegicus)


name: FUNDC1 is phosphorylated by CK2 (Schizosaccharomyces pombe)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Rattus norvegicus)


name: a ganglioside Fuc-GM1 + H2O <=> alpha-Fuc-(1->2)-beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-Glc + an N-acyl-sphingoid base


name: (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA => (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA


name: GBA1:SAPC hydrolyzes GlcCer (Homo sapiens)


name: SOAT1,2 transfer acyl group to CHOL forming CHEST (Danio rerio)


name: Furin cleaves pro-factor VII to factor VII (Gallus gallus)


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Schizosaccharomyces pombe)


name: H(+) + hydrogen sulfide + O-phospho-L-serine <=> L-cysteine + phosphate


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Dictyostelium discoideum)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Rattus norvegicus)


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Mus musculus)


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Bos taurus)


name: (3R)-hydroxytetradecanoyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine => holo-[ACP] + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Homo sapiens)


name: SCD desaturates ST-CoA to OLE-CoA (Drosophila melanogaster)


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Gallus gallus)


name: L-serine + NAD(+) = aminoacetaldehyde + CO2 + NADH


name: alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate + UMP => di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-glucose


name: Active MTORC1 phosphorylates ULK1 (Xenopus tropicalis)


name: Bile salts and acids dissociate from ALB (Bos taurus)


name: L-glutamate(out) + taurocholate(in) => L-glutamate(in) + taurocholate(out)


name: (2S)-2-nitrosobutanedioate + H2O => N,N-dihydroxy-L-aspartate


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + plaunotol => (2E,6E,10E)-geranylgeraniol + O2 + reduced [NADPH--hemoprotein reductase]


name: all-trans-zeaxanthin + O2 => (3R)-3-hydroxy-10'-apo-beta-carotenal + (3R)-hydroxy-beta-ionone


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Mus musculus)


name: N(2)-(1-hydroxy-2-oxopropyl)-GTP => GTP + methylglyoxal


name: p-6Y-VEGFR2 binds NCK (Canis familiaris)


name: hydrogen cyanide + pentanal <=> (2S)-2-hydroxyhexanenitrile


name: NCOA2(869-1464) binds KAT6A(1-1118) (Rattus norvegicus)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Canis familiaris)


name: H2O + L-phenylalanine + NAD(+) <=> 3-phenylpyruvate + H(+) + NADH + NH4(+)


name: HDAC10 deacetylates histone (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-farnesyl phosphate + H(+) + phosphate


name: an acyl-CoA + H(+) + malonyl-CoA <=> a 3-oxoacyl-CoA + CO2 + CoA


name: TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Mus musculus)


name: 2,4,6-trinitrotoluene + AH2 + glutathione = A + H2O + S-(2,4-dinitro-6-hydroxylaminotoluyl)glutathione


name: CYP3A4 can N-demethylate loperamide (Xenopus tropicalis)


name: Myosin phosphatase dephosphorylates PLK1 (Bos taurus)


name: 2 O2 + 2 reduced [NADPH--hemoprotein reductase] + silphinene-15-oate => gamma-lactone-2-keto[5.5.5.5]fenestrane + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: MET dimers autophosphorylate (Gallus gallus)


name: an (S)-cis-N-methyl-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-homocysteine => an (S)-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-methionine


name: a pyrimidine nucleobase + D-ribose 5-phosphate => a pyrimidine ribonucleoside 5'-phosphate + H2O


name: BP180 interacts intracellularly with plectin and integrin beta4 (Rattus norvegicus)


name: NAD(+) + taurochenodeoxycholate => 7-oxotaurolithocholate + H(+) + NADH


name: beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP-alpha-D-galactofuranose = [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 H(+) + 28 UDP


name: Inactivation of MAP2K1 by CDK1 (Homo sapiens)


name: H2O + NAD(+) + spermine monoaldehyde <=> 2 H(+) + N-(2-carboxyethyl)spermidine + NADH


name: chenodeoxycholate + UDP-alpha-D-glucuronate => chenodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP


name: Clustering of Integrin alphaIIb beta3 complexes (Danio rerio)


name: protoheme IX farnesyltransferase activity


name: NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Gallus gallus)


name: EML4 recruits NUDC to mitotic spindle (Mus musculus)


name: TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 (Homo sapiens)


name: Fall Back to Closed Pre-initiation Complex (Saccharomyces cerevisiae)


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Sus scrofa)


name: 2 (3,4-dimethoxyphenyl)methanol + H2O2 = 2 (3,4-dimethoxyphenyl)methanol radical + 2 H2O


name: FMO1:FAD N-oxidises TAM (Caenorhabditis elegans)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Gallus gallus)


name: IDUA) hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Xenopus tropicalis)


name: HMGB1 binds LTP (Caenorhabditis elegans)


name: L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine


name: DHODH:FMN binds DHODH inhibitors (Bos taurus)


name: 2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] => 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: RAC1 binds effectors at the plasma membrane (Canis familiaris)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: 7-deoxyloganate + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + loganate + oxidized [NADPH--hemoprotein reductase]


name: 4-hydroxy-L-proline(out) + chloride(out) + 2 Na(+)(out) = 4-hydroxy-L-proline + chloride(in) + 2 Na(+)(in)


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Xenopus tropicalis)


name: MAP2K6 phosphorylates PIP4K2B (Gallus gallus)


name: sGC stimulators bind sGC:NO (Mus musculus)


name: FA2H hydroxylates 1,2-saturated fatty acids (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + N-acyl-4-hydroxy-15-methylhexadecasphinganine <=> a 1,2-diacyl-sn-glycerol + N-acyl-4-hydroxy-15-methylhexadecasphinganine-1-phosphocholine


name: a ganglioside GM1 + H2O => a ganglioside GA1 + N-acetylneuraminate


name: PDGF binds to extracellular matrix proteins (Bos taurus)


name: acetate + diacetylglycerol + H(+) => H2O + triacetin


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Sus scrofa)


name: androsterone + H(+) + NADPH = 5alpha-androstane-3alpha,17beta-diol + NADP(+)


name: PIAS1,2-1 SUMOylates XRCC4 with SUMO1 (Homo sapiens)


name: L-leucine(in) + Na(+)(in) => L-leucine(out) + Na(+)(out)


name: beta-D-glucosylceramide + UDP-alpha-D-galactose <=> a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H(+) + UDP


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Caenorhabditis elegans)


name: (S)-malyl-CoA => acetyl-CoA + glyoxylate


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Homo sapiens)


name: Autocatalytic activation of bound proMMP2 (Danio rerio)


name: 2 H(+) + NADH + perillate => H2O + NAD(+) + perillyl aldehyde


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Rattus norvegicus)


name: 3',2'-cGAMP + diphosphate => pppA(2'-5')pG


name: (4Z,15Z)-bilirubin IXalpha + NAD(+) = biliverdin IXalpha + H(+) + NADH


name: ASICs bind STOML3, (STOM) (Caenorhabditis elegans)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (3E,7E)-dolathalia-3,7,11-triene + diphosphate


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Bos taurus)


name: AP-2 directly binds some endocytic cargo (Plasmodium falciparum)


name: pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle (Homo sapiens)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate <=> 14-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: mitomycin A + S-adenosyl-L-homocysteine => 6-demethylmitomycin A + S-adenosyl-L-methionine


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Drosophila melanogaster)


name: SYK binds the activated BCR (Gallus gallus)


name: ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate => ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine


name: L-aspartate + NADP(+) <=> H(+) + iminosuccinate + NADPH


name: alpha-cadinene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + GDP + H(+) => GDP-beta-L-fucose + L-seryl-[protein]


name: IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Sus scrofa)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: "linoleoyl-lipid Delta(12) conjugase (11E,13Z-forming)"


name: (2E,6E)-farnesyl diphosphate + H2O => (5S,9S,10S)-drim-7-en-11-ol + diphosphate


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: p-EPHB phosphorylates SDC2 (Rattus norvegicus)


name: VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Canis familiaris)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + H2O <=> 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H(+)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Homo sapiens)


name: DENND1s exchange GTP for GDP on RAB35 (Dictyostelium discoideum)


name: WNT ligands traffic to the Golgi (Xenopus tropicalis)


name: 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + H(+) + NADPH = 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-4H,6H,7H,8H-pyrrolo[1,2-a]pyrazine + NADP(+)


name: GBE1 catalyzes branch formation in polyGlc-GYG1 complexed with GYS1-b (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine <=> 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC (Canis familiaris)


name: Exogenous soluble antigen targeted to more stable early endosome (Bos taurus)


name: ADP + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(out) + H(+) + phosphate => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli)(in) + ATP + H2O


name: Interaction of DAP12 and KIR2DS1 (Homo sapiens)


name: NMNAT2 transfers an adenylyl group from ATP to NAMN to yield NAAD (Drosophila melanogaster)


name: MAPK8 phosphorylation (Schizosaccharomyces pombe)


name: hexadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase] => AMP + H(+) + hexadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: mandelate + O2 = H2O2 + phenylglyoxylate


name: menaquinol-8 + 2 O2 => 2 H(+) + menaquinone-8 + 2 superoxide


name: (R)-N-acetyl-1-phenylethylamine + H2O => (R)-1-phenylethylamine + acetate


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Sus scrofa)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Homo sapiens)


name: Relocalization of nuclearly localized Cyclin D1 to the cytoplasm (Caenorhabditis elegans)


name: cholesterol + phosphatidylcholine (lecithin) => cholesterol ester + 2-lysophosphatidylcholine (lysolecithin) (Drosophila melanogaster)


name: Activated FGFR1 phosphorylates FRS3 (Bos taurus)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Sus scrofa)


name: L-methionine(in) + Na(+)(in) => L-methionine(out) + Na(+)(out)


name: fraxetin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sideretin (reduced form)


name: Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Caenorhabditis elegans)


name: 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin] => (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin]


name: Formation of MSH2:MSH3 Complex (Gallus gallus)


name: 2-hydroxylamino-4,6-dinitrotoluene + H(+) + NADPH => 2-amino-4,6-dinitrotoluene + H2O + NADP(+)


name: ADP + D-allose(in) + H(+) + phosphate => ATP + D-allose(out) + H2O


name: GRK2 sequesters activated Gq (Canis familiaris)


name: STAT1 associates with IL6ST:IL6ST (Rattus norvegicus)


name: Interaction of E3 with substrate and E2-Ub complex (Mus musculus)


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Bos taurus)


name: LONP1 degrades mitochondrial matrix proteins (Saccharomyces cerevisiae)


name: REV1 binds AP-dsDNA (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycerol + inositol-1-phospho-N-(2-hydroxy-fatty acyl)-dihydroceramide => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + N-(2-hydroxy-fatty acyl)-dihydroceramide


name: 5,6-dihydrouracil + H2O <=> 3-(carbamoylamino)propanoate + H(+)


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Bos taurus)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Canis familiaris)


name: ent-copalyl diphosphate <=> diphosphate + ent-kaur-16-ene


name: PDE3A inhibitors bind PDE3A (Rattus norvegicus)


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Caenorhabditis elegans)


name: inositol phosphorylceramide synthase activity


name: Phosphorylation of BTK by p-SYK (Mus musculus)


name: (S)-acetoin + H(+) + NADH => (R,S)-butane-2,3-diol + NAD(+)


name: Conversion of Glycerol to Glycerol-3-phosphate (Canis familiaris)


name: ERK1/2/5 activate RSK1/2/3 (Drosophila melanogaster)


name: E-cadherin degradation by ADAM10, ADAM15 (Rattus norvegicus)


name: dimethylallyl diphosphate + siccayne => diphosphate + pestalodiol


name: (2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate


name: RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Mus musculus)


name: p-CD19:VAV binds PI3K and GRB2 (Bos taurus)


name: (11R)-dihydroartemisinic aldehyde + NADP(+) => (+)-artemisinic aldehyde + H(+) + NADPH


name: (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate => [5-(aminomethyl)furan-3-yl]methyl diphosphate + gamma-L-glutamyltyramine


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => 1-O-alkyl-2-acetyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: acetyl-CoA + holo-[ACP] => acetyl-[ACP] + CoA


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Xenopus tropicalis)


name: DIBOA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced [NADPH--hemoprotein reductase]


name: 2 Fe(III)-[cytochrome c553] + formate <=> CO2 + 2 Fe(II)-[cytochrome c553] + H(+)


name: RAS GAPs stimulate RAS GTPase activity (Homo sapiens)


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Drosophila melanogaster)


name: a dicarboxylate(in) + prostaglandin F2alpha(out) => a dicarboxylate(out) + prostaglandin F2alpha(in)


name: Nectin-1:Nectin-4 trans heterodimer formation (Canis familiaris)


name: 2 5'-dehydroinosine + O2 <=> 2 9-riburonosylhypoxanthine + 2 H(+)


name: CARM1 methylates arginine-18 (H3R17) of histone H3 (Homo sapiens)


name: acetyl-CoA + 3 AH2 + 18 H(+) + 10 malonyl-CoA + 8 NADPH = 3 A + 10 CO2 + 11 CoA + cordypyrone A + 8 H2O + 8 NADP(+)


name: The high affinity receptor complex binds to G-protein (Homo sapiens)


name: MEOS oxidizes ethanol to acetaldehyde (Dictyostelium discoideum)


name: PDPK1 phosphorylates AKT at T308 (Homo sapiens)


name: glyoxylate + L-tryptophan => glycine + indole-3-pyruvate


name: AKR1C3 reduces atRAL to atROL (Xenopus tropicalis)


name: 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose = 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP


name: L-lysyl-[histone] + S-adenosyl-L-methionine <=> H(+) + N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: NTP Binds Active Site of RNA Polymerase II (Gallus gallus)


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Gallus gallus)


name: ABCA12 transports lipids from cytosol to extracellular region (Bos taurus)


name: ATP + holo-[peptidyl-carrier protein] + L-arginine <=> AMP + diphosphate + L-arginyl-[peptidyl-carrier protein]


name: CHEK2 is recruited to DNA DSBs (Mus musculus)


name: 3xUb,p-S-NFkB p105:TPL2:ABIN2 dissociates due to degradation of p105 (Canis familiaris)


name: 2-oxoglutarate + berkeleyone A + O2 <=> CO2 + H2O + preaustinoid A + succinate


name: Association of DFF with alpha:beta importin (Homo sapiens)


name: Fe(3+) + Fe(II)-[cytochrome c] => Fe(2+) + Fe(III)-[cytochrome c]


name: O2 + octadecanoyl-CoA <=> (2E)-octadecenoyl-CoA + H2O2


name: GSDMD (1-275) binds bacterial cardiolipin (Rattus norvegicus)


name: H2O + L-serine + NAD(+) = 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GA2 + H(+) + UDP


name: SUMOylation of NOP58 with SUMO2 (Xenopus tropicalis)


name: kaempferol + S-adenosyl-L-methionine = H(+) + kaempferol 7-methyl ether + S-adenosyl-L-homocysteine


name: gibberellin A12 aldehyde + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => ent-7alpha-hydroxykaur-16-en-19-oate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 3'-phosphoadenylyl sulfate + 4-ethylphenol => 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: H2O + NADP(+) + pentyl acetate => H(+) + heptan-2-one + NADPH + O2


name: acetyl-CoA + N-terminal L-seryl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[protein]


name: ATP + H2O + L-cysteine(in) <=> ADP + H(+) + L-cysteine(out) + phosphate


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Bos taurus)


name: KSPG is secreted from the cell (Sus scrofa)


name: butan-1-ol + propanoyl-CoA => butyl propanoate + CoA


name: (1'S,5'S)-averufin + NADPH + O2 <=> 1'-hydroxyversicolorone + H2O + NADP(+)


name: AMP + diphosphate + GMP + 2 H(+) => ATP + NH4(+) + XMP


name: H(+) + N-(15Z-tetracosenoyl)-sphing-4-enine + phosphocholine => H2O + N-(15Z-tetracosenoyl)sphing-4-enine-1-phosphocholine


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Dictyostelium discoideum)


name: ADP + all-trans-hexaprenyl phosphate + H(+) => all-trans-hexaprenol + ATP


name: ATP + D-ribose 5-phosphate => 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)


name: FRS2 is phosphorylated by active TrkA receptor (Gallus gallus)


name: a ubiquinone + ethanol = a ubiquinol + acetaldehyde


name: Dimerization of KIT upon SCF binding (Xenopus tropicalis)


name: LKB1 forms a trimeric complex with STRAD and MO25 (Canis familiaris)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = diphosphate + fusoxypene A


name: 4-methylcatechol + CO2 + NADPH => (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NADP(+)


name: GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate


name: (S)-eriodictyol + O2 + reduced [NADPH--hemoprotein reductase] => (2S)-2-hydroxyeriodictyol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans (Bos taurus)


name: GSSeH condenses with GSH to form H2Se and GSSG (Homo sapiens)


name: (1R,3R)-chrysanthemal + H2O + NAD(+) => (1R,3R)-chrysanthemate + 2 H(+) + NADH


name: 1-docosanoylglycerol + H2O = docosanoate + glycerol + H(+)


name: Caspase-mediated cleavage of TJP1 (Sus scrofa)


name: GUCYs converts GTP to cGMP (Xenopus tropicalis)


name: 4-methylsulfanyl-2-oxobutanoate + H(+) <=> 3-methylsulfanylpropanal + CO2


name: COX10 transforms heme to heme O (Canis familiaris)


name: 4-ethylcatechol + NAD(+) => 3,4-dihydroxystyrene + H(+) + NADH


name: Gamma-carboxy pro-protein Z transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: TNF-alpha inhibitors bind to soluble TNF trimer (Homo sapiens)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Sus scrofa)


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Xenopus tropicalis)


name: Autocatalytic phosphorylation of FGFR4 (Xenopus tropicalis)


name: D-erythrose 4-phosphate + H2O + NAD(+) <=> 4-phospho-D-erythronate + 2 H(+) + NADH


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphoserine


name: CD36 gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)


name: brassicasterol 3-beta-D-glucoside + H(+) + UDP => brassicasterol + UDP-alpha-D-glucose


name: Anthrax lef cleaves target cell MAP2K6 (MEK6) (Homo sapiens)


name: 1'-hydroxyversicolorone + H(+) + NADPH + O2 => (2S,3S)-versiconal hemiacetal acetate + H2O + NADP(+)


name: p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Homo sapiens)


name: Spermidine  => N-acetylated spermidine (Mus musculus)


name: (3R)-hydroxyhexadecanoyl-CoA + NAD(+) <=> 3-oxohexadecanoyl-CoA + H(+) + NADH


name: Formation of the closed pre-initiation complex (Saccharomyces cerevisiae)


name: (2Z,6Z)-farnesyl diphosphate <=> (E)-beta-farnesene + diphosphate


name: (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanedioate + H(+) + H2O <=> 2-dehydro-D-glucose + L-glutamate


name: 2-oxobutanoate + L-kynurenine = (2S)-2-aminobutanoate + 4-(2-aminophenyl)-2,4-dioxobutanoate


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Mus musculus)


name: a fatty acylamide + H2O = a fatty acid + NH4(+)


name: ATP + H2O + sphing-4-enine(in) <=> ADP + H(+) + phosphate + sphing-4-enine(out)


name: 5-S-cysteinyldopa + L-dopaquinone => 5-S-cysteinyldopaquinone + L-dopa


name: MECP2 binds MOBP gene promoter (Homo sapiens)


name: hydrogen sulfide + O-succinyl-L-homoserine => L-homocysteine + succinate


name: 3,4-dihydroxyphenylacetyl-CoA + H2O = 3,4-dihydroxyphenylacetate + CoA + H(+)


name: COQ6 hydroxylates DHB (Canis familiaris)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Bos taurus)


name: ADP-D-glycero-beta-D-manno-heptose + L-seryl-[protein] = ADP + H(+) + O-(D-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein]


name: acetyl-CoA + oxalate = acetate + oxalyl-CoA


name: DBI, ACBD7 bind MCFA-CoA and LCFA-CoA (Schizosaccharomyces pombe)


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Canis familiaris)


name: Formation of active mTORC1 complex (Drosophila melanogaster)


name: an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 7-dehydrodesmosterol + S-adenosyl-L-methionine => 5-dehydroepisterol + H(+) + S-adenosyl-L-homocysteine


name: 2-dehydro-D-gluconate + ATP => 6-phospho-2-dehydro-D-gluconate + ADP + H(+)


name: (2E)-but-2-enal + hydrogen cyanide => (2S,3E)-2-hydroxypent-3-enenitrile


name: p-T816-PKN2 phosphorylates NOS3 (eNOS) on serine-1179 (Saccharomyces cerevisiae)


name: ERBB4s80:STAT5A complex translocates to the nucleus (Caenorhabditis elegans)


name: E2F6 binds the PRC1 complex (Canis familiaris)


name: CYP4B1 12-hydroxylates ARA (Xenopus tropicalis)


name: Activated NOD1 oligomerizes (Canis familiaris)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Homo sapiens)


name: 9-(acyloxy)-octadecanoate + a 2-acylglycerol => 9-hydroxy-octadecanoate + a 1,2-diacyl-sn-glycerol


name: Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Mus musculus)


name: p-Y407-YAP1 translocates from the cytosol to the nucleoplasm (Rattus norvegicus)


name: glyphosate + H2O + O2 <=> aminomethylphosphonate + glyoxylate + H(+) + H2O2


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-octadecanoyl ethanolamine => H2O + N-octadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: N-acetyl-D-mannosamine 6-phosphate => N-acetyl-D-glucosamine 6-phosphate


name: 4-chloro-L-lysine + AH2 + O2 => A + formaldehyde + H2O + L-2-amino-4-chloropent-4-enoate + NH4(+)


name: aminoacetone + CO2 => (2S)-2-amino-3-oxobutanoate + H(+)


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Plasmodium falciparum)


name: LIG1 binds APEX1 and PCNA at SSB (Drosophila melanogaster)


name: Met1-linked polyubiquitin deubiquitinase activity


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Homo sapiens)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)


name: Fe-coproporphyrin III + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + 2 CO2 + heme b + 2 L-methionine


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Rattus norvegicus)


name: 2'-deoxyadenosine + ATP => ADP + dAMP + H(+)


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Drosophila melanogaster)


name: D-glutamate + H2O + O2 => 2-oxoglutarate + H2O2 + NH4(+)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Caenorhabditis elegans)


name: asperterpenoid A + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => asperterpenoid B + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Bos taurus)


name: Caspase-8 activates BID by cleavage (Gallus gallus)


name: cholesterol + UDP-alpha-D-glucose => cholesteryl 3-beta-D-glucoside + H(+) + UDP


name: acetyl-CoA + benzyl alcohol = benzyl acetate + CoA


name: TRIP11:IFT20 dissociates (Drosophila melanogaster)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O


name: Interaction of E3 ligase with ISG15:E2 complex (Mus musculus)


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Xenopus tropicalis)


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Schizosaccharomyces pombe)


name: hydrogen sulfide + L-cysteate => L-cysteine + sulfite


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Canis familiaris)


name: RNA(n)-3'-guanine ribonucleotide <=> 2',3'-cyclophospho-GMP + RNA(n)


name: 9beta-pimara-7,15-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 9beta-pimara-7,15-dien-19-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: Gastrin binds to CCK-B receptor (Rattus norvegicus)


name: Dab2 is recruited to the junctional plaques (Homo sapiens)


name: H2O + O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] => beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-seryl-[protein]


name: Defective HK1 does not phosphorylate Glc to form G6P (Homo sapiens)


name: Caspase-mediated cleavage of PKC theta (Rattus norvegicus)


name: a fatty acid + H(+) + long chain acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol => H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: 2 H(+) + limonin 17-beta-D-glucoside + UDP => H2O + limonin + UDP-alpha-D-glucose


name: 3-oxo-(12Z,15Z,18Z,21Z)-tetracosatetraenoyl-CoA + CO2 + CoA => (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA


name: acetate + spermidine => H2O + N(8)-acetylspermidine


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA = 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: Methylthio-ribose-P = Methylthio-ribulose-P (Homo sapiens)


name: RAC3 GAPs stimulate RAC3 GTPase activity (Canis familiaris)


name: (2R,3S)-homoisocitrate + NAD(+) <=> 2-oxoadipate + CO2 + NADH


name: aldehydo-D-ribose 5-phosphate <=> D-ribose 5-phosphate


name: H2O2 + tetradecanoate <=> (2S)-hydroxytetradecanoate + H2O


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine = a 2-acyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: C-terminal L-cysteinyl-[HypE protein] + carbamoyl adenylate => AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + H(+)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Homo sapiens)


name: Loading of dopamine into synaptic veiscles (Sus scrofa)


name: PAO:FAD oxidises NASPM to PTCN (Sus scrofa)


name: 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + nonanedioate


name: RHOA:GTP translocates to the ER membrane (Caenorhabditis elegans)


name: a tRNA with a 3' CCA end + ATP + 2 CTP = a tRNA with a 3' CCACCA end + 3 diphosphate


name: ADP + bacteriochlorophyllide g + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate = 3,8-divinyl chlorophyllide a + ATP + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin]


name: "3,8-divinyl chlorophyllide a reductase"


name: an R-cob(III)alamin(in) => an R-cob(III)alamin(out)


name: AFG3L2 binds mitochondrial matrix proteins (Bos taurus)


name: (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate


name: Interleukin-32 binds proteinase-3 (Bos taurus)


name: 1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + CoA => 1-octadecanoyl-sn-glycero-3-phosphocholine + acetyl-CoA


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: FABP5:atRA translocates from cytosol to nucleoplasm (Xenopus tropicalis)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Rattus norvegicus)


name: Active FLT3 binds to GRAP2 (Canis familiaris)


name: eugenol + S-adenosyl-L-methionine = H(+) + O-methyleugenol + S-adenosyl-L-homocysteine


name: acetyl-CoA + L-methionine sulfoximine = CoA + H(+) + N-acetyl-L-methionine sulfoximine


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Mus musculus)


name: 2 caldariellaquinol + n H(+)(in) + O2 = 2 caldariellaquinone + n H(+)(out) + 2 H2O


name: PGLYRP2 binds bacterial peptidoglycan (Bos taurus)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Caenorhabditis elegans)


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Danio rerio)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Rattus norvegicus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Bos taurus)


name: 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA <=> 1-dodecanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Xenopus tropicalis)


name: (3R)-hydroxy-5-methylhexanoyl-[ACP] = (2E)-5-methylhexenoyl-[ACP] + H2O


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Rattus norvegicus)


name: 6-chloropyridine-2,3,5-triol + FADH2 + O2 = 3,6-dihydroxypyridine-2,5-dione + chloride + FAD + 3 H(+) + H2O


name: octadecanoyl-CoA + taurine <=> CoA + H(+) + N-octadecanoyl-taurine


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Caenorhabditis elegans)


name: 2'-deoxycytidine + a ribonucleoside 5'-triphosphate = a ribonucleoside 5'-diphosphate + dCMP + H(+)


name: H2O + L-prolinylglycine => glycine + L-proline


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Rattus norvegicus)


name: 9alpha-copalyl diphosphate + H2O => diphosphate + syn-copalol


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Canis familiaris)


name: ATP + H(+) + NADPH + octanoate = AMP + diphosphate + NADP(+) + octanal


name: ATP2B4 binds to NOS1, inhibiting it (Mus musculus)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Mus musculus)


name: PIN1 binds phosphorylated PIP4K2B (Gallus gallus)


name: PC is exchanged with PI by PITPNB (Homo sapiens)


name: Gq activation by TP receptor (Mus musculus)


name: (4E,11E)-2-hydroxytrideca-4,11-dien-1,2,3-tricarboxylate + CoA + H(+) => (2E,10E)-dode-2,10-dicenoyl-CoA + H2O + oxaloacetate


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Rattus norvegicus)


name: AKR1B1 reduces Glc to D-sorbitol (Xenopus tropicalis)


name: Recognition and Binding of Core Promoter Elements by TFIID (Caenorhabditis elegans)


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-L-ribitol = 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: "teichoic acid ribitol-phosphate primase"


name: RCC1 stimulates GDP to GTP exchange on RAN (Homo sapiens)


name: Translocation of p27 to the nucleoplasm (Gallus gallus)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+) => (2R)-3-phosphoglycerate + GDP-D-glucose


name: (R)-2-hydroxyglutarate(out) + 3 Na(+)(out) => (R)-2-hydroxyglutarate(in) + 3 Na(+)(in)


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Rattus norvegicus)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Bos taurus)


name: ADP(in) + FAD(out) <=> ADP(out) + FAD(in)


name: cyanidin 3-O-glucoside 2-O-glucuronosyltransferase activity


name: Transhomodimerization of Nectins (Canis familiaris)


name: gibberellin A4 16alpha,17 epoxidase activity


name: D-galactose(out) + N(pros)-phospho-L-histidyl-[protein] => D-galactose 6-phosphate(in) + L-histidyl-[protein]


name: CHEK1 phosphorylates RAD51 (Saccharomyces cerevisiae)


name: p-Y348-SYK binds VAV family (Homo sapiens)


name: Na(+)(out) + urate(in) => Na(+)(in) + urate(out)


name: S-adenosyl-L-methionine + thiocyanate = methyl thiocyanate + S-adenosyl-L-homocysteine


name: CTP(in) + dGTP(out) => CTP(out) + dGTP(in)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Saccharomyces cerevisiae)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + octadecanoate => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Drosophila melanogaster)


name: H(+) + malonyl-[ACP] + tetradecanoyl-CoA => 3-oxohexadecanoyl-[ACP] + CO2 + CoA


name: beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-beta-L-fucose => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: Phosphorylation of BIM by JNK (Mus musculus)


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Caenorhabditis elegans)


name: H2O + N-(4-aminobenzoyl)-L-glutamate = 4-aminobenzoate + L-glutamate


name: soyasapogenol A + UDP-alpha-D-glucuronate => H(+) + soyasapogenol A 3-O-beta-D-glucuronate + UDP


name: GLA hydrolyzes PSAP(195-273):Gb3Cer:PE (Rattus norvegicus)


name: IL12RB1:TYK2 binds IL12RB2:JAK2 (Canis familiaris)


name: 16,17-didehydropregnenolone 3-beta-D-glucoside + H(+) + UDP => 16,17-didehydropregnenolone + UDP-alpha-D-glucose


name: queuosine(34) in tRNA(Tyr) + UDP-alpha-D-galactose = H(+) + O-5''-beta-D-galactosylqueuosine(34) in tRNA(Tyr) + UDP


name: PTPN3 dephosphorylates MAPK12 (Rattus norvegicus)


name: TFIIH binds GG-NER site to form a verification complex (Canis familiaris)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Gallus gallus)


name: CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3-yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: D-aspartyl-tRNA(Asp) + H2O = D-aspartate + H(+) + tRNA(Asp)


name: (9Z,12Z)-octadecadienoate(out) + ATP(in) + CoA(in) + H(+)(out) <=> (9Z,12Z)-octadecadienoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: H2O + N-succinyl-L-glutamate => L-glutamate + succinate


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + lactose => beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + H2O


name: NAAA hydrolyses NAEs to FAs and ethanolamine (Caenorhabditis elegans)


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Mus musculus)


name: inosine(out) + Na(+)(out) <=> inosine(in) + Na(+)(in)


name: 4-O-demethylbarbatate + S-adenosyl-L-methionine => proatranorin I + S-adenosyl-L-homocysteine


name: SLC9B1/C2 exchange Na+ for H+ (Sus scrofa)


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Caenorhabditis elegans)


name: 22-oxodocosanoate + H2O + NAD(+) <=> docosanedioate + 2 H(+) + NADH


name: 1-chloro-3-nitrobenzene + NADH + O2 = 4-chlorocatechol + NAD(+) + nitrite


name: SLC9C1 exchanges Na+ for H+ (Homo sapiens)


name: Proteasome mediated degradation of Cyclin D1 (Schizosaccharomyces pombe)


name: Association of procollagen type XXIII (Bos taurus)


name: Neuroglobin:oxygen dissociates (Canis familiaris)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Bos taurus)


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate <=> ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Caenorhabditis elegans)


name: ATP + L-lysyl-5'-AMP = L-lysine + P(1),P(4)-bis(5'-adenosyl) tetraphosphate


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Canis familiaris)


name: 5'-dehydroadenosine + H2O + O2 <=> 9-riburonosyladenine + H(+) + H2O2


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Drosophila melanogaster)


name: Detection of damage during initiation of DNA synthesis in S-phase (Plasmodium falciparum)


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Caenorhabditis elegans)


name: RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Caenorhabditis elegans)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Drosophila melanogaster)


name: chrysanthemyl diphosphate synthase activity


name: 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH => 2-dehydro-3-deoxy-L-fuconate + NAD(+)


name: ISGylation of E2 conjugating enzymes (Rattus norvegicus)


name: 1,10-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: HIF-alpha translocates from cytosol to nucleus (Rattus norvegicus)


name: an N(4)-(oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] + H2O => an oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-D-GlcNAc + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein]


name: 10-deoxymethymycin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + methymycin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ADP + ATP + 2 H(+) => H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate


name: acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity


name: a 2-acylglycerol + an acyl-CoA = a 1,2-diacylglycerol + CoA


name: ADP + H(+) + S-methyl-5-thio-alpha-D-ribose 1-phosphate => 5-(methylsulfanyl)-D-ribose + ATP


name: Interaction of PECAM-1 and PLC gamma1 (Mus musculus)


name: 3-hydroxy-D-kynurenine + S-adenosyl-L-methionine <=> 3-hydroxy-4-methyl-D-kynurenine + H(+) + S-adenosyl-L-homocysteine


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Bos taurus)


name: Spermidine  => N-acetylated spermidine (Danio rerio)


name: (2E,6E)-farnesyl diphosphate => (-)-(E)-beta-caryophyllene + diphosphate


name: Oxysterol binds to the UGT1A3 gene:NR1H2,3:RXR:NCOR complex (Rattus norvegicus)


name: maltose + H2O => 2 D-glucose (maltase-glucoamylase) (Sus scrofa)


name: ATP + L-glutamate + NH4(+) <=> ADP + H(+) + L-glutamine + phosphate


name: beta-muricholoyl-CoA + deoxycholate => beta-muricholate + deoxycholoyl-CoA


name: MVB Vesicle Formation (Schizosaccharomyces pombe)


name: 7,8-dihydroxyflavone + S-adenosyl-L-methionine = 7-hydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: (S)-2,3-dihydrodipicolinate + NAD(+) = dipicolinate + H(+) + NADH


name: [thyroglobulin]-L-tyrosine + H(+) + H2O2 + iodide = [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Xenopus tropicalis)


name: 3beta,20alpha-dihydroxy-5beta-pregnane + NADP(+) => 3beta-hydroxy-5beta-pregnane-20-one + H(+) + NADPH


name: Arachidonate is epoxidated to 14,15-EET by CYP(5) (Sus scrofa)


name: a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+) => a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Rattus norvegicus)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine => an N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: Inactive G alpha (i) reassociates with G beta:gamma (Drosophila melanogaster)


name: LIN7, CASK and APBA1 bind (Drosophila melanogaster)


name: a 1-acyl-sn-glycero-3-phosphocholine + H2O => a 1-acyl-sn-glycerol + H(+) + phosphocholine


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Mus musculus)


name: D-galactose + NAD(+) => D-galactono-1,5-lactone + H(+) + NADH


name: (1R,5R)-beta-pinene + diphosphate => (2E)-geranyl diphosphate


name: USP30 deubiquitinates Ub-MOM proteins (Schizosaccharomyces pombe)


name: FRK phosphorylates PTEN (Xenopus tropicalis)


name: dihydrozeatin + NADP(+) => H(+) + NADPH + zeatin


name: Enzyme-bound ATP is released (Drosophila melanogaster)


name: miR-33 binds to the 3'UTR of the ABCA1 mRNA (Homo sapiens)


name: Formation of BRCA1-A complex at DNA DSBs (Gallus gallus)


name: an N-(fatty acyl)-L-asparagine + H2O => a fatty acid + L-asparagine


name: AP4 transports APP from trans-Golgi network to endosome lumen (Homo sapiens)


name: methylenetetrahydrofolate reductase (NAD(P)H) activity


name: Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) (Rattus norvegicus)


name: L-lysyl-[lipoyl-carrier protein] + N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] = L-lysyl-[glycine-cleavage complex H protein] + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: PGLYRP3,4 binds bacterial peptidoglycan (Danio rerio)


name: Cleavage of Procaspase-3 by the apoptosome (Mus musculus)


name: METAP1/2 demethylates GNAT1 (Canis familiaris)


name: 3'-phosphoadenylyl sulfate + 4-ethylphenol = 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: PEX3:PEX19:class I PMP dissociates (Mus musculus)


name: H2O + sphinga-4E,14Z-dienine-1-phosphate = phosphate + sphinga-4E,14Z-dienine


name: H2O + long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol => a fatty acid + H(+) + long chain 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: YAP1 binds TEAD2 (Caenorhabditis elegans)


name: adenosine 3',5'-bisphosphate + H(+) + taurolithocholate 3-sulfate => 3'-phosphoadenylyl sulfate + taurolithocholate


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Bos taurus)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Bos taurus)


name: 2 ATP + GTP = 3',3',3'-cAAG + 3 diphosphate


name: 26-hydroxyhexacosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => hexacosanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Ligand-independent phosphorylation of overexpressed FGFR1c (Homo sapiens)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Xenopus tropicalis)


name: Autophosphorylation of PAK (Rattus norvegicus)


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Canis familiaris)


name: Formation of ARC coactivator complex (Sus scrofa)


name: CYP3A4, CYP2B6 bind ritonavir (Rattus norvegicus)


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Bos taurus)


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Drosophila melanogaster)


name: Cleavage of ethenocytosine by TDG glycosylase  (Bos taurus)


name: ITGBL1 gene expression is stimulated by RUNX2 (Homo sapiens)


name: ACER3 hydrolyzes phytoceramide (Canis familiaris)


name: 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 <=> 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: ISGylation of E2 conjugating enzymes (Caenorhabditis elegans)


name: AXIN1 gene expression is inhibited by ESR1 and stimulated by RUNX1 (Homo sapiens)


name: 3-(6-sulfo-alpha-D-quinovosyl)glycerol + H2O => 6-sulfo-alpha-D-quinovose + glycerol


name: 2-deoxy-D-glucose 6-phosphate + H2O <=> 2-deoxy-D-glucose + phosphate


name: SYS1 binds AcM-ARFRP1 (Plasmodium falciparum)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Homo sapiens)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Schizosaccharomyces pombe)


name: a 5'-end phospho-ribonucleoside-ribonucleotide-RNA + AMP + 2 diphosphate + H(+) => a 5'-end ribonucleotide-RNA + a ribonucleoside 5'-triphosphate + ATP + H2O


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(in) + ATP + H2O <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(out) + ADP + H(+) + phosphate


name: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] <=> formate + 2 H(+) + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite


name: (1R,4S)-menthone + NADP(+) <=> (R)-pulegone + H(+) + NADPH


name: Formation of dehydro-hydroxylysino-norleucine cross-links (Canis familiaris)


name: 2-oxoglutarate + a 1,N(2)-etheno-2'-deoxyguanosine in double-stranded DNA + H2O + O2 = a 2'-deoxyguanosine in double-stranded DNA + CO2 + glyoxal + succinate


name: a cytidine in rRNA + S-adenosyl-L-methionine => an N(4)-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: GH:GHR:JAK2 complex undergoes a conformational change (Gallus gallus)


name: (R)-lactate + chloride + H(+) => (S)-2-chloropropanoate + H2O


name: NADPH transfers electrons to FDXR (Homo sapiens)


name: WNT5A:FZD4 is endocytosed (Rattus norvegicus)


name: sulfate adenylyltransferase (ADP) activity


name: N-terminal N-methyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine