name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O


name: MTORC1 dissociates from ULK complex (Gallus gallus)


name: NEK6 and NEK7 phosphorylate EML4 (Caenorhabditis elegans)


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Canis familiaris)


name: SUMOylation of DDX17 with SUMO1 (Mus musculus)


name: Envoplakin, periplakin, involucrin, SPR binding mediated by TGM1 crosslinking (Homo sapiens)


name: dimethylallyl diphosphate + H2O + yaequinolone E = [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate


name: SCARB1:ligand is endocytosed (Rattus norvegicus)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Mus musculus)


name: PTK6 phosphorylates BCAR1 (Xenopus tropicalis)


name: (R)-2-hydroxyglutarate(out) + 3 Na(+)(out) <=> (R)-2-hydroxyglutarate(in) + 3 Na(+)(in)


name: benzene + H(+) + NADH + O2 = cis-1,2-dihydrobenzene-1,2-diol + NAD(+)


name: indole-3-pyruvate imine dimer => CO2 + NH4(+) + protodeoxyviolaceinate


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + 2 N-(2,3-dihydroxybenzoyl)-L-serine => Fe(III)-enterobactin + H(+) + 3 H2O


name: CTP + N-acetyl-D-glucosamine = CDP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: PDPK1 phosphorylates PKN1,2,3 (Sus scrofa)


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Xenopus tropicalis)


name: 2,3,5,6-tetrachlorohydroquinone + H(+) + NAD(+) => 2,3,5,6-tetrachloro-1,4-benzoquinone + NADH


name: AMP + diphosphate + H(+) + staphyloferrin A => ATP + citrate + N(5)-[(S)-citryl]-D-ornithine


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methenyltetrahydrofolate + NADH


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Drosophila melanogaster)


name: Phosphorylation and activation of PLCG (Canis familiaris)


name: 3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvate + H(+) + NADH => NAD(+) + tetrahydro-4-hydroxyphenylpyruvate


name: 2,4-dinitrophenyl-S-glutathione(out) + ADP + H(+) + phosphate => 2,4-dinitrophenyl-S-glutathione(in) + ATP + H2O


name: a primary amine + S-adenosyl-L-methionine <=> a methylated primary amine + H(+) + S-adenosyl-L-homocysteine


name: JMJD6 demethylates Me2sR4-HIST1H4 (Bos taurus)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Plasmodium falciparum)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Bos taurus)


name: Mitochondrial FPGS-1 transforms THF to THFPG (Dictyostelium discoideum)


name: HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 (Sus scrofa)


name: MVD decarboxylates MVA5PP to IPPP (Xenopus tropicalis)


name: Phosphorylated PER is phosphorylated by CK2 (Drosophila melanogaster)


name: BP180 interacts intracellularly with plectin and integrin beta4 (Sus scrofa)


name: E2F6 binds CBX5 gene promoter (Homo sapiens)


name: Autophosphorylation of BTK/ITK (Drosophila melanogaster)


name: Tachykinin receptor 2 (NK2) binds to nuerokinin A (Mus musculus)


name: n H(+)(out) + pregnenolone sulfate(out) => n H(+)(in) + pregnenolone sulfate(in)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Caenorhabditis elegans)


name: CO2 + NH4(+) + protodeoxyviolaceinate => indole-3-pyruvate imine dimer


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Bos taurus)


name: (E)-phenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => L-phenylalanine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: mRNA5 is translated to protein M (Homo sapiens)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Bos taurus)


name: mTORC1 binds RHEB:GTP (Drosophila melanogaster)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Sus scrofa)


name: PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: HSPG2 (perlecan) binds alpha-dystroglycan (Homo sapiens)


name: 2-oxoglutarate + putrescine <=> 1-pyrroline + H2O + L-glutamate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-homocysteine => L-lysyl(4)-[histone H3] + 2 S-adenosyl-L-methionine


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Sus scrofa)


name: CYSLTR1 binds CYSLTR1 antagonists (Homo sapiens)


name: Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 (Danio rerio)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: a ganglioside Ac-O-8-GT3 => a ganglioside Ac-O-9-GT3


name: a 3alpha-hydroxysteroid + NADP(+) = a 3-oxosteroid + H(+) + NADPH


name: Formation of the Spliceosomal P complex and exon ligation (Mus musculus)


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: Inhibin-A binding to TGFBR3 (Homo sapiens)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ATP + L-glutamate => (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + H(+) + phosphate


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 <=> 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O


name: Inactivation of APC/C via CDC20 sequestration (Drosophila melanogaster)


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Bos taurus)


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Sus scrofa)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Rattus norvegicus)


name: androst-5-en-3beta,17beta-diol + NAD(+) <=> 17beta-hydroxy-androst-5-en-3-one + H(+) + NADH


name: Formation of P-TEFb complex (Rattus norvegicus)


name: (R)-glycerate + GDP-alpha-D-mannose <=> (2R)-2-O-(alpha-D-mannosyl)-glycerate + GDP + H(+)


name: (E)-cinnamaldehyde + H2O + O2 => (E)-cinnamate + H(+) + H2O2


name: N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Rattus norvegicus)


name: DLD dimer dehydrogenates dihydrolipoyl (Dictyostelium discoideum)


name: C-ter TLR7 dimer binds imiquimod (Mus musculus)


name: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate => 10-deacetyl-2-debenzoylbaccatin III


name: (2S)-sakuranetin + O2 + reduced [NADPH--hemoprotein reductase] = (2S)-7-methylcarthamidin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Xenopus tropicalis)


name: Collagen type X binds Integrin alpha2beta1 (Homo sapiens)


name: H2O + hydroquinone + NAD(+) => H(+) + NADH + O2 + phenol


name: 1-octanoyl-sn-glycero-2,3-cyclic phosphate + choline => 1-octanoyl-sn-glycero-3-phosphocholine


name: pre-VLDL translocates from RER membrane to SER lumen (Gallus gallus)


name: (1'S,5'S)-averufin + H2O => (S)-5'-oxoaverantin + H(+)


name: 2,3,5,6-tetrachlorohydroquinone + H(+) + NAD(+) = 2,3,5,6-tetrachloro-1,4-benzoquinone + NADH


name: BCL6 gene expression is stimulated by FOXO3,FOXO4,(FOXO1) (Homo sapiens)


name: Aquaporin-1 passively transports water out of cell (Mus musculus)


name: (2R,3S)-2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine = (2R,3S)-2,7-dihydroxy-4'-methoxyisoflavanone + H(+) + S-adenosyl-L-homocysteine


name: HMG CoA => acetoacetic acid + acetyl CoA (Homo sapiens)


name: Phosphorylation of PIP2 to PIP3 by PI3K (Rattus norvegicus)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Homo sapiens)


name: (1S,2S)-OPC-8 + ATP + CoA => AMP + diphosphate + OPC8-CoA


name: gamma-L-glutamylputrescine + H2O + O2 = 4-(gamma-L-glutamylamino)butanal + H2O2 + NH4(+)


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Drosophila melanogaster)


name: CYP2F1 dehydrogenates 3-methylindole (Xenopus tropicalis)


name: JAK2 phosphorylation of GHR (Homo sapiens)


name: 8-oxo-dGTP + H2O => 8-oxo-dGDP + H(+) + phosphate


name: ATP + H2O + phosphite(out) <=> ADP + H(+) + phosphate + phosphite(in)


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Danio rerio)


name: H2O + raucaffricine = D-glucose + vomilenine


name: PTEN undergoes monoubiquitination (Rattus norvegicus)


name: MDM2 ubiquitinates phosphorylated MDM4 (Rattus norvegicus)


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-Gly)-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + 2 glycyl-tRNA(Gly) = 2 H(+) + MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-tri-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 tRNA(Gly)


name: RDH12 reduces atRAL to atROL (Danio rerio)


name: USP19 deubiquitinates RNF123 (Gallus gallus)


name: petunidin 3-O-beta-D-glucoside + UDP => petunidin + UDP-alpha-D-glucose


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Mus musculus)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Homo sapiens)


name: C3PO hydrolyzes cleaved passenger strand (Schizosaccharomyces pombe)


name: [small archaeal modifier protein]-C-terminal Gly-Gly + ATP + H(+) <=> [small archaeal modifier protein]-C-terminal Gly-Gly-AMP + diphosphate


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Gallus gallus)


name: (R)-carnitine + an acyl-CoA => CoA + O-acyl-(R)-carnitine


name: CO2 + mugineate + succinate => 2'-deoxymugineate + 2-oxoglutarate + O2


name: H2O + N-(9Z-octadecenoyl)-L-tyrosine <=> (9Z)-octadecenoate + L-tyrosine


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Rattus norvegicus)


name: H(+) + N-hexadecanoylsphing-4-enine + phosphocholine => H2O + N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) => diphosphate + DNA(n+1)


name: an acyl-CoA + H(+) + malonyl-CoA = a 3-oxoacyl-CoA + CO2 + CoA


name: (3R)-5-guanidino-3-methyl-2-oxopentanoate + L-aspartate <=> (3R)-3-methyl-L-arginine + oxaloacetate


name: PGRMC2:Hemes translocate to the nucleus (Canis familiaris)


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Canis familiaris)


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Dictyostelium discoideum)


name: L-seryl-[protein] + N-acetyl-D-glucosamine => 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H2O


name: gilteritinib-resistant FLT3 mutants don't bind gilteritinib (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Xenopus tropicalis)


name: ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)


name: YKI binds to WTS (Drosophila melanogaster)


name: dTDP + H(+) + N(omega)-(alpha-L-rhamnosyl)-L-arginyl-[protein] => dTDP-beta-L-rhamnose + L-arginyl-[protein]


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Mus musculus)


name: PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: "23S rRNA pseudouridine(955/2504/2580) synthase"


name: CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + H(+) => acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose


name: MITF-M dimer binds the DICER1 gene (Homo sapiens)


name: HLCS biotinylates 6x(PCCA:PCCB) (Sus scrofa)


name: Phosphorylation of STAT1 at Ser727 (Sus scrofa)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Formation of ADAR2  homodimer (Bos taurus)


name: MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) (Rattus norvegicus)


name: protein C-terminal leucine carboxyl O-methyltransferase activity


name: PDPK1 phosphorylates AKT2 (Mus musculus)


name: 2 GTP <=> 3',3'-c-di-GMP + 2 diphosphate


name: H2O + IMP <=> 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Schizosaccharomyces pombe)


name: (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate = all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + H(+) + UDP


name: IL35 binds IL12RB2:IL12RB2 receptor (Mus musculus)


name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Sus scrofa)


name: alpha-D-glucose 1-phosphate + ATP <=> ADP + alpha-D-glucose 1,6-bisphosphate + H(+)


name: a ubiquinol + 4 H(+)(out) + NAD(+) => a ubiquinone + 5 H(+)(in) + NADH


name: Release of docked dopamine loaded synaptic vesicle (Homo sapiens)


name: 1-haloalkane + H2O => a halide anion + a primary alcohol + H(+)


name: H2O + neurotensin-(1-8) <=> L-arginine + neurotensin-(1-7)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Saccharomyces cerevisiae)


name: IFN alpha/beta binds to IFNAR2 (Homo sapiens)


name: 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + H(+) + phosphate => 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H2O


name: Connexin synthesis (generic) (Mus musculus)


name: ADP + H(+) + ophthalmate + phosphate => ATP + gamma-L-glutamyl-(2S)-2-aminobutanoate + glycine


name: 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate <=> 2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Homo sapiens)


name: 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-(10Z-heptadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: 15-methylhexadecanoate + H(+) + NADPH + O2 => H2O + NADP(+) + omega-hydroxy-15-methyl-hexadecanoate


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Gallus gallus)


name: [sulfur-carrier protein]-L-cysteine + L-cysteine => [sulfur-carrier protein]-S-sulfanyl-L-cysteine + L-alanine


name: 3'-CMP + H(+) => 2',3'-cyclophospho-CMP + H2O


name: (S)-2-amino-6-oxohexanoate + holo-[LYS2 peptidyl-carrier protein] + NADP(+) = H(+) + L-2-aminoadipyl-[LYS2 peptidyl-carrier protein] + NADPH


name: ATP + D-glucuronate => 1-phospho-alpha-D-glucuronate + ADP + H(+)


name: TP53I3 oxidoreductase generates unstable semiquinones (Sus scrofa)


name: gibberellin A12 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => gibberellin A15 + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: SLC2A9 transports Fru, Glc, urate (Drosophila melanogaster)


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Drosophila melanogaster)


name: 4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 H(+) + 2 NADH + O2 = 2,5-dihydroxypyridine + H2O + 2 NAD(+) + succinate semialdehyde


name: FOXO1 binds POMC gene promoter (Homo sapiens)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Mus musculus)


name: a fatty acylamide + H2O <=> a fatty acid + NH4(+)


name: Formation of the PA28gamma homoheptamer (Sus scrofa)


name: (R)-carnitine(out) + 4-(trimethylamino)butanoate(in) <=> (R)-carnitine(in) + 4-(trimethylamino)butanoate(out)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> (-)-somaliensene B + diphosphate


name: 9-cis-retinal + O2 + reduced [NADPH--hemoprotein reductase] => 9-cis-retinoate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Bos taurus)


name: 4-methylcatechol + NAD(+) + nitrite => 4-nitrotoluene + NADH + O2


name: ADRA2A,B,C bind ADR,NAd (Drosophila melanogaster)


name: diphosphate + sophoraflavanone G => dimethylallyl diphosphate + leachianone G


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Bos taurus)


name: H(+) + NADPH + O2 + tryprostatin B <=> demethoxyfumitremorgin C + 2 H2O + NADP(+)


name: Expression of SRF in cardiogenesis (Homo sapiens)


name: SREBP1A,1C binds the FASN promoter (Homo sapiens)


name: LONP1 binds mitochondrial inner membrane proteins (Gallus gallus)


name: 2 a 2,3-di-O-phytanyl-sn-glycerophospholipid + 2 AH2 + 4 S-adenosyl-L-methionine <=> 4 5'-deoxyadenosine + 2 A + a glycerol dibiphytanyl glycerol tetraether phospholipid + 4 H(+) + 4 L-methionine


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 13-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: an N-acyl-L-homoserine lactone + H2O <=> a carboxylate + L-homoserine lactone


name: Formation of ORC(1-6) complex (Bos taurus)


name: cirsimaritin + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + scutellarein 7-methyl ether


name: Arachidonate is hydroxylated to 20-HETE by CYP(3) (Bos taurus)


name: 9beta-pimara-7,15-dien-19-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-dien-19-al + O2 + reduced [NADPH--hemoprotein reductase]


name: HS3ST1 sulfates GlcN at C3 in heparan sulfate (Canis familiaris)


name: ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine = 1-(10Z-heptadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Rattus norvegicus)


name: Phosphorylation of Syntaxin-4 (Danio rerio)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Sus scrofa)


name: guanidinoacetate + H2O <=> glycine + urea


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Homo sapiens)


name: D-ribulose 5-phosphate => (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)


name: 6-amino-6-deoxyfutalosine + H(+) + H2O <=> futalosine + NH4(+)


name: CPT1A transfers PALM to CAR (Bos taurus)


name: Phosphorylated MAPKs translocate into the nucleus (Dictyostelium discoideum)


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Mus musculus)


name: protein ADP-ribosyltransferase-substrate adaptor activity


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Bos taurus)


name: PPP1CC dephosphorylates PLK1 (Schizosaccharomyces pombe)


name: 3,4-dihydroxybenzoate + ATP + H(+) = 3,4-dihydroxybenzoyl-5'-AMP + diphosphate


name: Digestion of 1-6 linkages of limit dextrins to yield maltose, maltotriose, longer maltosides, and glucose (Bos taurus)


name: coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n)


name: "coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase"


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Canis familiaris)


name: USP48 cleaves polyubiquitin (Gallus gallus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase] <=> 1-[(9R,10S)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: POFUT2 transfers fucose to TSR domain-containing proteins (Gallus gallus)


name: 2 A + a carotenoid beta-end derivative => a carotenoid phi-end derivative + 2 AH2


name: H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + uridine(1498) in 16S rRNA


name: ADP + coenzyme F430 + phosphate => 15,17(3)-seco-F430-17(3)-acid + ATP


name: H2O + N-acetyl-L-phenylalanine = acetate + L-phenylalanine


name: GNLY is transferred to the phagosome (Canis familiaris)


name: CBX4 SUMOylates BMI1 in PRC1 with SUMO1 (Xenopus tropicalis)


name: BIL binds GSTA1, FABP1 (Caenorhabditis elegans)


name: alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] => alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + D-galactofuranose(out) + H2O = ADP + D-galactofuranose(in) + H(+) + phosphate


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Rattus norvegicus)


name: Proteasome mediated degradation of COP1 (Canis familiaris)


name: Peptide transfer from P-site tRNA to the A-site tRNA (Homo sapiens)


name: ATP + O-(5'-adenylyl)-L-tyrosyl-[protein] <=> diphosphate + O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein]


name: Ubiquitinated IkB is degraded (Gallus gallus)


name: H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP <=> diphosphate + UDP-N-acetyl-alpha-D-glucosamine


name: acetyl-CoA + 7 H(+) + 5 malonyl-CoA + 3 NADPH <=> 5-methyl-1-naphthoate + 5 CO2 + 6 CoA + 4 H2O + 3 NADP(+)


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H2O + NAD(+) = 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + 2 H(+) + NADH


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)


name: DCC interacts with DIP13alpha (Canis familiaris)


name: 1,5-anhydro-D-fructose + H(+) + NADPH => 1,5-anhydro-D-mannitol + NADP(+)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Drosophila melanogaster)


name: 1,2-dioctanoyl-3-O-beta-D-galactosyl-sn-glycerol + H2O = H(+) + octanoate + octanoyl-3-(beta-D-galactosyl)-sn-glycerol


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Mus musculus)


name: benzoate + 2 H(+) + NADPH => benzaldehyde + H2O + NADP(+)


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Canis familiaris)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 <=> 2-glyceryl-prostaglandin G2


name: MeSeOH is reduced to MeSeH by TXNRD1 (Caenorhabditis elegans)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose = an isogloboside iGb3Cer + H(+) + UDP


name: 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH => 5alpha-androstane-3alpha,17beta-diol + NADP(+)


name: FN3K phosphorylates ketosamines (Canis familiaris)


name: K11-linked polyubiquitin modification-dependent protein binding


name: EOMES, WDR5, KAT2A, and TBXT bind the MESP1 gene (Homo sapiens)


name: CGRP receptor can bind calcitonin gene-related peptides (Bos taurus)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Mus musculus)


name: UROD decarboxylates URO1 to COPRO1 (Dictyostelium discoideum)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Gallus gallus)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Mus musculus)


name: 2-aminobenzoyl-AMP + CoA <=> AMP + anthraniloyl-CoA + H(+)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Danio rerio)


name: (6E)-8-hydroxygeraniol + NADP(+) <=> (6E)-8-hydroxygeranial + H(+) + NADPH


name: MST1R autophosphorylates (Gallus gallus)


name: coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] => coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n)


name: 3-hydroxyphenylpropionic acid transmembrane transporter activity


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Caenorhabditis elegans)


name: Formation of ARC coactivator complex (Homo sapiens)


name: ABCB11 transports bile salts from cytosol to extracellular region (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol-3'-phosphate) + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + phosphate


name: 3-O-methyl-L-dopa(out) + L-phenylalanine(in) = 3-O-methyl-L-dopa(in) + L-phenylalanine(out)


name: Pregn-5-ene-3,20-dione-17-ol isomerizes to 17-hydroxyprogesterone (Danio rerio)


name: phenol + S-adenosyl-L-methionine <=> anisole + H(+) + S-adenosyl-L-homocysteine


name: a ubiquinone + succinate <=> a ubiquinol + fumarate


name: PG is hydrolyzed to 1-acyl LPG by PLA2[16] (Mus musculus)


name: 3-oxo-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + NADP(+)


name: 4'-hydroxyacetophenone + H(+) + NADPH + O2 <=> 4-acetoxyphenol + H2O + NADP(+)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Gallus gallus)


name: 2',3'-cyclophospho-GMP + RNA(n) => RNA(n)-3'-guanine ribonucleotide


name: p-STAT1 dimer binds KPNA1 (Homo sapiens)


name: TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (Sus scrofa)


name: H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu) => L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein]


name: Activated FGFR4 binds PLCG1 (Danio rerio)


name: salicylate + UDP-alpha-D-glucose <=> 1-O-salicyl-beta-D-glucose + UDP


name: (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H(+) + NADPH <=> (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+)


name: Binding of SHC1 to insulin receptor (Homo sapiens)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(36-hydroxyhexatriacontenoyl)-sphing-4-enine = a diacylglycerol + an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontenoyl)-sphing-4-enine


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Rattus norvegicus)


name: 3-oxooctanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxyoctanoyl-[ACP] + NADP(+)


name: 6 H(+) + 2 hydrogen sulfide + 2 sulfite => 4 H2O + O2 + 4 sulfur


name: Phosphorylation of LAT by p-SYK (Mus musculus)


name: PLC beta-mediated PIP2 hydrolysis (Sus scrofa)


name: N-(5-phospho-beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate


name: WWTR1 (TAZ) binds ZO-2 (TJP2) (Bos taurus)


name: STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Canis familiaris)


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Canis familiaris)


name: IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Sus scrofa)


name: uridine in snRNA <=> pseudouridine in snRNA


name: 1-O-alkyl-sn-glycerol + phosphate => 1-O-alkyl-sn-glycero-3-phosphate + H2O


name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria (Homo sapiens)


name: SRD5A2 binds SRD5A2 inhibitors (Mus musculus)


name: Autocatalytic activation of MMP7 (Xenopus tropicalis)


name: 2-hydroxy-7,8-dihydropteroate + diphosphate => (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminosalicylate


name: N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Caenorhabditis elegans)


name: Activated CIT binds KIF14 and PRC1 (Canis familiaris)


name: MKRN1 polyubiquitinates PTEN (Xenopus tropicalis)


name: MEN1 binds MLL1 complex (Drosophila melanogaster)


name: 2-methylpropanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein]


name: S-(acetaldehyde)-L-cysteine => (4S)-5,6-dihydro-4H-1,3-thiazine-4-carboxylate + H(+) + H2O


name: 1-acyl-2-(9Z,12Z,15Z-octadecatrienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 1-acyl-2-(9Z,12Z-octadecadienoyl)-3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Glucagon binds to Glucagon receptor (Mus musculus)


name: isopropylmalate transmembrane transporter activity


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Bos taurus)


name: protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity


name: Dermatan sulfate can be further sulfated on position 2 of iduronate (Homo sapiens)


name: Inactive G alpha (q) reassociates with G beta:gamma (Canis familiaris)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Schizosaccharomyces pombe)


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Bos taurus)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Sus scrofa)


name: DOLK phosphorylates DCHOL to DOLP (Rattus norvegicus)


name: OPRK1 gene expression is stimulated by MECP2 (Homo sapiens)


name: voltage-gated sodium channel activity involved in SA node cell action potential


name: nitric oxide transmembrane transporter activity


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Drosophila melanogaster)


name: (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate => (9Z,12Z,15Z)-octadecatrienoate + O2


name: SRD5A2 dehydrogenates TEST to DHTEST (Schizosaccharomyces pombe)


name: GSS:Mg2+ dimer synthesizes GSH (Saccharomyces cerevisiae)


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Drosophila melanogaster)


name: (3R)-3-[(carboxymethyl)amino]butanoate + 2-oxoglutarate + O2 => (3R)-3-{[carboxy(hydroxy)methyl]amino}butanoate + CO2 + succinate


name: CMBL hydrolyses OM to OLMS (Mus musculus)


name: 4-hydroxy-all-trans-beta-carotene + A + H2O => AH2 + all-trans-beta-carotene + O2


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine <=> Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: CYP26C1 4-hydroxylates 9cRA (Rattus norvegicus)


name: (2R)-3-sulfolactate + NAD(+) => 3-sulfopyruvate + H(+) + NADH


name: anthranilate + S-adenosyl-L-methionine = O-methyl anthranilate + S-adenosyl-L-homocysteine


name: Branching and elongation of mother and daughter filaments (Mus musculus)


name: 2-oxoglutarate + pyridoxamine 5'-phosphate <=> L-glutamate + pyridoxal 5'-phosphate


name: NQO2:FAD dimer reduces quinones to hydroquinones (Homo sapiens)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Caenorhabditis elegans)


name: BAP1 binds BRCA1:BARD1 heterodimer (Homo sapiens)


name: ATXN3 family cleave Ub chains (Mus musculus)


name: Arachidonate is epoxidated to 14,15-EET by CYP(5) (Canis familiaris)


name: luvungin A + O2 + reduced [NADPH--hemoprotein reductase] => (1S)-1-hydroxy-luvungin A + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + O2 => glycine betaine + 2 H(+) + phosphate


name: estrone 3-sulfate(out) + glutarate(in) => estrone 3-sulfate(in) + glutarate(out)


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)


name: 2 H2O + 4 oxidized [4Fe-4S]-[ferredoxin] + taurine = glycine + 6 H(+) + 4 reduced [4Fe-4S]-[ferredoxin] + sulfite


name: H2O + N-(9Z-octadecenoyl)-L-serine <=> (9Z)-octadecenoate + L-serine


name: an aldehyde + H2O + NAD(+) => a carboxylate + 2 H(+) + NADH


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Danio rerio)


name: an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 2 Fe(III)-[cytochrome b5] + H2O + N-acyl-4-hydroxyeicosasphinganine


name: Autophosphorylation of PAK1,2,3 (Danio rerio)


name: MTMR8 binds MTMR9 (Saccharomyces cerevisiae)


name: H2O + NAD(+) + pseudopaline => (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + 2-oxoglutarate + H(+) + NADH


name: HK1 phosphorylates Mannose to Man6P (Canis familiaris)


name: Stalling of DNA replication fork and RPA binding (Rattus norvegicus)


name: Coactivators are recruited to liganded PPARG:RXRA heterodimer (Bos taurus)


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Sus scrofa)


name: ADAM10/17 cleaves ligand-bound NOTCH1 PEST domain mutants to produce NEXT1 PEST domain mutants (Homo sapiens)


name: L-threonine + tRNA(Ile) => H2O + L-threonyl-tRNA(Ile)


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Sus scrofa)


name: USP10 deubiquitinates SNX3, CFTR (Homo sapiens)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Sus scrofa)


name: PCK2 phosphorylates OA to yield PEP (Rattus norvegicus)


name: (2E)-dodecenoyl-CoA + H2O <=> (2E)-dodecenoate + CoA + H(+)


name: (S)-methylmalonyl-CoA + H2O = CoA + H(+) + methylmalonate


name: Interaction of Tie2 with Ang2 (Sus scrofa)


name: (6S)-5-formyl-5,6,7,8-tetrahydrofolate + H(+) => (6R)-5,10-methenyltetrahydrofolate + H2O


name: maltose + H2O => 2 D-glucose (maltase-glucoamylase) (Gallus gallus)


name: Neurolysin degrades neurotensin (Sus scrofa)


name: (E)-caffeate + H(+) + pyruvate => (E)-caffeoylpyruvate + H2O


name: (9Z,12Z)-tetradecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z)-tetradecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose => beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Canis familiaris)


name: JMJD6 demethylates Me2R3-histone H3 (Mus musculus)


name: Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Mus musculus)


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Sus scrofa)


name: I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Bos taurus)


name: erythritol + NADP(+) => D-erythrose + H(+) + NADPH


name: TPI1 isomerizes GA3P to DHAP (Schizosaccharomyces pombe)


name: Activation of RAS by p-KIT bound SOS1 (Homo sapiens)


name: 2 fonsecin B + H(+) + NADPH + O2 <=> aurasperone B + 2 H2O + NADP(+)


name: H2O + N-acetyl-D-glucosamine + O2 <=> H(+) + H2O2 + N-acetyl-D-glucosaminate


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Drosophila melanogaster)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Rattus norvegicus)


name: 4-methyl-5-nitrocatechol + NADH + O2 => 2-hydroxy-5-methylquinone + H(+) + H2O + NAD(+) + nitrite


name: 4-hydroxybenzoate + bromide + 2 H(+) + NADPH + O2 => 3-bromo-4-hydroxybenzoate + 2 H2O + NADP(+)


name: uridine(65) in tRNA <=> pseudouridine(65) in tRNA


name: 3'-dephospho-CoA + GTP = CoA + GDP + H(+)


name: (6R)-10-formyltetrahydrofolate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Bos taurus)


name: Dimeric TGFB1 does not bind TGFBR2 MSI frameshift mutants (Homo sapiens)


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 3-hydroxy-L-phenylalanine => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2


name: H(+) + S-sulfanyl-L-cysteinyl-[SoxY protein] + sulfate => H2O + S-sulfosulfanyl-L-cysteinyl-[SoxY protein]


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: PTCH is internalized (Rattus norvegicus)


name: 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+) => 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2


name: POLB incorporates a single nucleotide in place of excised AP residue in NEIL1,NEIL2-mediated AP site resolution (Danio rerio)


name: prunetin-5-O-beta-D-glucuronide + UDP => prunetin + UDP-alpha-D-glucuronate


name: (1R,2R,4R)-dihydrocarveol + NAD(+) <=> (1R,4R)-dihydrocarvone + H(+) + NADH


name: [protein]-dithiol + NADP(+) => [protein]-disulfide + H(+) + NADPH


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Caenorhabditis elegans)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Homo sapiens)


name: H(+) + NADH + xanthine => H2O + hypoxanthine + NAD(+)


name: (7Z)-hexadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,7Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: ADO oxidises 2AET to HTAU (Canis familiaris)


name: COMT transfer CH3 from AdoMet to 3,4DHBNZ (Danio rerio)


name: EGFR gene expression is stimulated by TFAP2C (Homo sapiens)


name: Corticotropin cleavage from POMC (Canis familiaris)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Drosophila melanogaster)


name: (11Z,14Z,17Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (E)-phenylacetaldehyde oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] <=> (Z)-1-(glutathione-S-yl)-2-phenylacetohydroximate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: glycine + H2O + NAD(+) => glyoxylate + H(+) + NADH + NH4(+)


name: 4-amino-L-phenylalanine + ATP + holo-[peptidyl-carrier protein] <=> 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AMP + diphosphate


name: 2-hydroxy-3-methyldodecanoyl-CoA + CO2 + succinate => 2-oxoglutarate + 3-methyldodecanoyl-CoA + O2


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Homo sapiens)


name: ULK3 phosphorylates GLI (Drosophila melanogaster)


name: p-T38-PPP1R14A binds MLCP (Xenopus tropicalis)


name: 2-nonadioyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-nonadioyl-sn-glycero-3-phosphocholine + H2O


name: SLITs bind keratan sulfate (Caenorhabditis elegans)


name: PRLR binds SCF beta-TrCP complex (Rattus norvegicus)


name: D-cysteine + H2O + O2 = 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)


name: 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) <=> (+)-costunolide + H2O


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Sus scrofa)


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Bos taurus)


name: E2F6:TFDP1 binds to MGA:MAX (Gallus gallus)


name: (E)-ferulate + ATP + CoA <=> (E)-feruloyl-CoA + AMP + diphosphate


name: GPX4-2 reduces 17(R)-Hp-DHA to 17(R)-HDHA (Plasmodium falciparum)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)


name: phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] <=> (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit]


name: 6-diphospho-1D-myo-inositol pentakisphosphate + H2O => 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: MWH binds to RHO1:GTP and is activated (Drosophila melanogaster)


name: 5-guanidino-2-oxopentanoate + a plastoquinol + NH4(+) => a plastoquinone + H2O + L-arginine


name: CDK2:CCNA phosphorylates TERF2 (Xenopus tropicalis)


name: MBTPS2 (S2P) cleaves ATF6 (ATF6-alpha) (Gallus gallus)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Sus scrofa)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA


name: Secretion of ADM (Adrenomedullin) (Bos taurus)


name: cholesterol + H(+) + NADH + O2 = 7-dehydrocholesterol + 2 H2O + NAD(+)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Xenopus tropicalis)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Schizosaccharomyces pombe)


name: CHEK2 is recruited to DNA DSBs (Sus scrofa)


name: PRMT1 arginine-methylates RUNX1 (Drosophila melanogaster)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Gallus gallus)


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Dictyostelium discoideum)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Mus musculus)


name: Downregulation of c-Kit signaling by SOCS6 (Homo sapiens)


name: p-PKR dimer phosphorylates CDK1 (Gallus gallus)


name: L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] + octadecanoyl-CoA => CoA + H(+) + N(6)-octadecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: 15-deoxy-Delta(12,14)-prostaglandin J2 + glutathione => 15-deoxy-Delta(12,14)-prostaglandin J2-S-(R)-glutathione


name: (S)-malate + succinyl-CoA <=> (S)-malyl-CoA + succinate


name: 2,2-dihydroxyspheroidene <=> H2O + spheroiden-2-one


name: calcidiol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = calcitriol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: D-xylose + NADP(+) => D-xylono-1,5-lactone + H(+) + NADPH


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Drosophila melanogaster)


name: 3beta-hydroxy-5alpha-androstan-17-one + NAD(+) <=> 5alpha-androstan-3,17-dione + H(+) + NADH


name: H2O + N-acetyl-D-galactosamino-1,5-lactone = H(+) + N-acetyl-D-galactosaminate


name: adenosine(4) in tRNA(His) + S-adenosyl-L-methionine => 2'-O-methyladenosine(4) in tRNA(His) + H(+) + S-adenosyl-L-homocysteine


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Mus musculus)


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Gallus gallus)


name: cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(4447) in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: Processing of SCF isoform 1 (Homo sapiens)


name: (R)-reticuline + S-adenosyl-L-methionine => (R)-laudanine + H(+) + S-adenosyl-L-homocysteine


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: 16alpha,17alpha-dihydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 6beta,16alpha,17alpha-trihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + methylenediurea <=> N-(carboxyaminomethyl)urea + NH4(+)


name: an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP => a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine


name: a guanosine in 18S rRNA + S-adenosyl-L-methionine <=> an N(7)-methylguanosine in 18S rRNA + S-adenosyl-L-homocysteine


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Saccharomyces cerevisiae)


name: p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1 (Rattus norvegicus)


name: 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine => 2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine


name: 1-tetradecanoyl-sn-glycerol + H(+) + phosphocholine => 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NADP(+)


name: H2O + N-(9Z-hexadecenoyl) ethanolamine = (9Z)-hexadecenoate + ethanolamine


name: E2F6:TFDP1 binds to MGA:MAX (Canis familiaris)


name: 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: N(omega),N(omega)-dimethyl-L-arginine + pyruvate => 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine


name: p-Y-STATs translocate to nucleus (Gallus gallus)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H(+) + hexadecanoate


name: QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) (Homo sapiens)


name: a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)


name: A + all-trans-lycopene <=> AH2 + all-trans-3,4-didehydrolycopene


name: 1-O-hexadecyl-2-propanoyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: Interaction of SHP1 and KIT (Gallus gallus)


name: cholesteryl 3-beta-D-glucoside + N-(15Z-tetracosenoyl)-sphing-4-enine => beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enine + cholesterol


name: H2O + N-(dodecanoyl)-sphinganine = dodecanoate + sphinganine


name: (R)-carnitine + decanoyl-CoA = CoA + O-decanoyl-(R)-carnitine


name: ATP + butanoate + H(+) + NADPH <=> AMP + butanal + diphosphate + NADP(+)


name: OGDH dimer decarboxylates 2-OG (Caenorhabditis elegans)


name: RNA Pol II initiates transcription from damaged DNA template (Bos taurus)


name: NAD(+) + ribitol => D-ribulose + H(+) + NADH


name: 5-methoxytryptamine + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + serotonin


name: deoxynogalonate + O2 = H(+) + H2O + nogalonate


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Canis familiaris)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Danio rerio)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + D-galactose => a globoside Gb3Cer (d18:1(4E)) + H2O


name: 6beta-hydroxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cortisol + O2 + reduced [NADPH--hemoprotein reductase]


name: 32-oxoeburicol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 32-hydroxyeburicol + O2 + reduced [NADPH--hemoprotein reductase]


name: MKL1 translocates from cytosol to the nucleus (Gallus gallus)


name: Clathrin recruits auxilins to the clathrin-coated vesicle (Bos taurus)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O => (17E)-cheilanthenediol


name: 5-dehydro-4-deoxy-D-glucarate => 2-hydroxy-3-oxopropanoate + pyruvate


name: RNF8 and RNF168 ubiquitinate H2AFX (Bos taurus)


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Canis familiaris)


name: PRDM4 (SC1) binds to p75NTR (Homo sapiens)


name: POLD,POLE binds deISGylated PCNA after TLS (Bos taurus)


name: guanidinoacetate + L-ornithine => glycine + L-arginine


name: SAR1 Activation And Membrane Binding (Sus scrofa)


name: Thrombin binding to GP1b:IX:V (Sus scrofa)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Drosophila melanogaster)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Sus scrofa)


name: STAT3-dependent MIR-21 gene expression (Homo sapiens)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Plasmodium falciparum)


name: 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Sus scrofa)


name: Integrin alpha2beta1 binds laminin-332 (Homo sapiens)


name: AH2 + trichloroethene <=> (Z)-1,2-dichloroethene + A + chloride + H(+)


name: Interaction of GRB2:SOS complex with p-SHC1 (Canis familiaris)


name: p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane (Xenopus tropicalis)


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Rattus norvegicus)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Sus scrofa)


name: CRYM reduces P2C to PPCA (Drosophila melanogaster)


name: Phosphorylation of ITAM motifs in CD3 complexes (Canis familiaris)


name: (9Z)-octadecenamide + H2O = (9Z)-octadecenoate + NH4(+)


name: Cleavage of uracil by UNG glycosylase (Schizosaccharomyces pombe)


name: CYP3A4 monooxygenates ATVL to 4-OH-ATVL (Sus scrofa)


name: GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Mus musculus)


name: Factor I inactivates plasma Factor H-bound C3b (Xenopus tropicalis)


name: CTLH E3 ligase ubiquitinates LDHA (Bos taurus)


name: a 1,1-dimethyl-3-phenylurea + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => a 1-methyl-3-phenylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Sus scrofa)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Caenorhabditis elegans)


name: atROL binds RBP1 to form RBP1:atROL (Gallus gallus)


name: H(+) + N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine => an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine


name: Formation of the 43S pre-initiation complex (Drosophila melanogaster)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Caenorhabditis elegans)


name: PLC-gamma 1 binds to p-EGFRvIII mutant (Homo sapiens)


name: Caspase-mediated cleavage of gelsolin (Danio rerio)


name: (2E,6E)-farnesyl diphosphate + H(+) + NADPH + O2 <=> (2E,6E)-omega-hydroxy-farnesyl diphosphate + H2O + NADP(+)


name: 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP-alpha-D-glucose <=> 4-O-{[(2R)-2-alpha-D-glucosyl-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n H(+) + n UDP


name: DLAT trimer transfers acetyl to CoA (Homo sapiens)


name: a ganglioside GM1b + CMP-N-acetyl-beta-neuraminate => a ganglioside GD1alpha + CMP + H(+)


name: (11R)-hydroxymethyl carlactonoate + CO2 + succinate => (11R)-methyl carlactonoate + 2-oxoglutarate + O2


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Homo sapiens)


name: an N-acylsphing-4-enine + ATP => ADP + an N-acylsphing-4-enine 1-phosphate + H(+)


name: USP30 deubiquitinates Ub-MOM proteins (Gallus gallus)


name: CYP4F11 16-hydroxylates 3OH-PALM (Xenopus tropicalis)


name: Furin cleaves pro-protein S to protein S (Canis familiaris)


name: Expression of NOTCH1 in paraxial mesoderm (Homo sapiens)


name: 4beta-methylzymosterol-4alpha-carboxylate + NAD(+) <=> 3-dehydro-4-methylzymosterol + CO2 + NADH


name: p-AMPK:AMP binds the ULK complex (Canis familiaris)


name: UCMA gene expression is stimulated by RUNX2 and SP7 (Homo sapiens)


name: Binding of Syk tyrosine kinase (Xenopus tropicalis)


name: 3,5,7-trioxododecanoyl-CoA => CO2 + CoA + olivetol


name: CO2 + decanal + H(+) + succinate + sulfate => 2-oxoglutarate + decyl sulfate + O2


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Saccharomyces cerevisiae)


name: acetyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] = CoA + myricetin 3-O-[(6-O-acetyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: glycolate + NAD(+) = glyoxylate + H(+) + NADH


name: p-STAT5 dissociates from the receptor complex (Homo sapiens)


name: ATP + lipid A disaccharide (E. coli) = ADP + H(+) + lipid IVA (E. coli)


name: AMP + benzaldehyde + diphosphate + NADP(+) => ATP + benzoate + H(+) + NADPH


name: (S)-methylmalonyl-CoA + H2O <=> CoA + H(+) + methylmalonate


name: D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+) = diphosphate + GDP-D-glycero-alpha-D-manno-heptose


name: K63 polyubiquitinated RIP2 associates with the TAK1 complex (Canis familiaris)


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Canis familiaris)


name: PTPN1 and PTPN2 dephosphorylate MET (Xenopus tropicalis)


name: 3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + UDP-alpha-D-glucuronate => 15-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + UDP


name: 2 H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UMP => H2O + UDP-N-acetyl-alpha-D-galactosamine


name: H(+) + 2 malonyl-CoA + nicotinyl-CoA => 4-hydroxy-6-(pyridin-3-yl)-2H-pyran-2-one + 2 CO2 + 3 CoA


name: eNoSC dimethylates histone H3 at lysine-9 (Dictyostelium discoideum)


name: geranylgeranyl diphosphate + H2O => (13E)-labda-7,13-dien-15-ol + diphosphate


name: D-tryptophanyl-tRNA(Trp) + H2O <=> D-tryptophan + tRNA(Trp)


name: 2xTPK1:Mg2+ phosphorylates THMN (Homo sapiens)


name: 5-aminomethyl-dUMP in DNA + acetyl-CoA <=> 5-acetylaminomethyl-dUMP in DNA + CoA + H(+)


name: H(+) + hnu + octadecanoate => CO2 + heptadecane


name: PIAS4 SUMOylates TP53BP1 with SUMO1 (Rattus norvegicus)


name: chlorophyll a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = 7(1)-hydroxychlorophyll a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: (2S)-3-(4-hydroxyphenyl)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O => 2-dehydro-D-glucose + L-tyrosine


name: Caspase-mediated cleavage of alpha adducin (Homo sapiens)


name: Dissociation of the P2Y purinoceptor 12:Gi complex (Homo sapiens)


name: 3-((4-bromophenyl)sulfanyl)-2-oxopropanoate + L-glutamate => 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine


name: dGTP + methylglyoxal = N(2)-(1-hydroxy-2-oxopropyl)-dGTP


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Caenorhabditis elegans)


name: EDNRA, EDNRB bind non-selective ERAs (Gallus gallus)


name: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate


name: 2-hydroxy-5-carboxymethylmuconate semialdehyde + H2O + NAD(+) <=> (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate + 2 H(+) + NADH


name: Formation of Ragulator complex (Bos taurus)


name: beta-D-fructose 1,6-bisphosphate + H2O => beta-D-fructose 6-phosphate + phosphate


name: glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)


name: ATXN3 family cleave Ub chains (Sus scrofa)


name: KAT5 acetylates ATM at DNA DSBs (Gallus gallus)


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Caenorhabditis elegans)


name: PIAS3 SUMOylates MITF with SUMO1 (Sus scrofa)


name: H2O + P(1),P(6)-bis(5'-adenosyl) hexaphosphate => adenosine 5'-tetraphosphate + ADP + 2 H(+)


name: General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Mus musculus)


name: H(+) + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + UDP => N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-mannosamine


name: a dicarboxylate(out) + xanthurenate(in) => a dicarboxylate(in) + xanthurenate(out)


name: Formation of Processive Complex on the C-strand of the telomere (Rattus norvegicus)


name: 10-deoxymethynolide + dTDP-alpha-D-desosamine => 10-deoxymethymycin + dTDP + H(+)


name: H(+)(in) + minocycline(out) => H(+)(out) + minocycline(in)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-tryptophan => indole-3-pyruvate + L-kynurenine


name: a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O <=> acetate + an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol


name: FLT3 ITD- and STAT5-dependent CDKN1A gene expression (Homo sapiens)


name: 14,15-EET is hydrolysed to 14,15-DHET by EPHX2 (Rattus norvegicus)


name: (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O => (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-4,8-dimethyldeca-4,8-dienoyl-CoA + H(+) + NADH => (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-4,8-dimethyldeca-4,8-dienoyl-CoA + NAD(+)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Xenopus tropicalis)


name: cysteamine S-phosphate + H2O <=> cysteamine + phosphate


name: 3-hydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine = 3-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine


name: (2S)-3-(4-hydroxyphenyl)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O <=> 2-dehydro-D-glucose + L-tyrosine


name: DBT transfers BCAA to CoA (Plasmodium falciparum)


name: (2E)-decenedioyl-CoA + H2O <=> (3S)-hydroxydecanedioyl-CoA


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Drosophila melanogaster)


name: acetyl-CoA + an alkane-alpha,omega-diamine <=> an N-acetylalkane-alpha,omega-diamine + CoA + H(+)


name: HGD dioxygenates homogentisate (Danio rerio)


name: G protein-coupled photoreceptor activity


name: P2Y9 receptor can bind to LPA (Caenorhabditis elegans)


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Rattus norvegicus)


name: SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: TCF:Beta-catenin binds SOX proteins (Sus scrofa)


name: (E)-feruloyl-CoA + (E)-feruloylacetyl-CoA + H2O <=> CO2 + 2 CoA + curcumin


name: 2-acyl LPC is acylated to PC by LPCAT (Saccharomyces cerevisiae)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Canis familiaris)


name: DP1 receptor can bind PGD2 (Homo sapiens)


name: RAP1A exchanges GDP for GTP (Saccharomyces cerevisiae)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Mus musculus)


name: ASA- acetylates PTGS2 (Canis familiaris)


name: Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Danio rerio)


name: oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity


name: 14-3-3 zeta binding allows recruitment of PI3K (Sus scrofa)


name: Activated FGFR2 phosphorylates SHC1 (Rattus norvegicus)


name: HES5 gene expression is stimulated by NOTCH4 (Homo sapiens)


name: cholate + L-alanine = H2O + L-alanocholate


name: The acetyl group from acetyl-CoA is transferred to the NAT2 (Sus scrofa)


name: 4-acetamidobutanal + H2O2 + NH4(+) => H2O + N-acetylputrescine + O2


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Dictyostelium discoideum)


name: Association of Rb with Cyclin E:Cdk2 complexes (Canis familiaris)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Rattus norvegicus)


name: KSRP recruits RNA degradation activities (Sus scrofa)


name: 2 ATP + 2 cob(II)inamide + 2 H2O + reduced [electron-transfer flavoprotein] => 2 adenosylcob(III)inamide + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate


name: PTPN3 binds p-T183,Y185 MAPK12 (Sus scrofa)


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Bos taurus)


name: betaine aldehyde + H2O + NADP(+) => glycine betaine + 2 H(+) + NADPH


name: FMN + glyoxylate + 2 H(+) + H2O + sulfite => FMNH2 + O2 + sulfoacetate


name: FA2H hydroxylates 1,2-saturated fatty acids (Sus scrofa)


name: H(+) + H2 + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> reduced coenzyme F420-(gamma-L-Glu)(n)


name: (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate <=> 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate


name: ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H(+) + N(6)-biotinyl-L-lysyl-[protein]


name: "biotin--[biotin carboxyl-carrier protein] ligase"


name: dodecanoyl-CoA + hexadecan-1-ol = CoA + hexadecanyl dodecanoate


name: RAC1 binds PAK1-3 (Drosophila melanogaster)


name: Arachidonate is hydroxylated to 18-HETE by CYP(1) (Danio rerio)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Caenorhabditis elegans)


name: ribose 5-phosphate <=> D-ribulose 5-phosphate (Mus musculus)


name: H2O + methyl salicylate = H(+) + methanol + salicylate


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Sus scrofa)


name: LRRC14 binds IKBKB and CHUK (Rattus norvegicus)


name: 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 H2O <=> 2 AMP + ATP + 2 H(+)


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na(+)(in) => 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na(+)(out)


name: Trans-autophosphorylation of ERBB4 homodimers (Canis familiaris)


name: MAP2K2 binds MAPK1 (Saccharomyces cerevisiae)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = diphosphate + neoverrucosan-5beta-ol


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + ATP <=> 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + ADP + H(+)


name: structural constituent of peritrophic membrane


name: [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine <=> [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate


name: diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein] => N(pros)-phospho-L-histidyl-[protein] + N,N'-diacetylchitobiose(out)


name: MMP14 (MT1-MMP) binds TIMP2 (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol <=> a 1-acyl-sn-glycero-3-phosphocholine + a triacyl-sn-glycerol


name: "cytokinin riboside 5'-monophosphate phosphoribohydrolase"


name: Expression of MESP1 in cardiogenesis (Homo sapiens)


name: glutathione(out) + 3 Na(+)(out) = glutathione(in) + 3 Na(+)(in)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Rattus norvegicus)


name: CHEK2 phosphorylates TTC5 (Canis familiaris)


name: 3,3',5-triiodo-L-thyronine(in) + L-tyrosine(out) => 3,3',5-triiodo-L-thyronine(out) + L-tyrosine(in)


name: (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecenyl)-glycerol <=> 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: SETD8 methylates TP53 (Drosophila melanogaster)


name: RAF1 binds p21 RAS:GTP (Xenopus tropicalis)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Danio rerio)


name: Addition of galactose to Core 6 glycoprotein (Drosophila melanogaster)


name: H(+)(out) + L-tyrosine(out) => H(+)(in) + L-tyrosine(in)


name: Proteasomal cleavage of substrate (Bos taurus)


name: all-trans-beta-carotene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Aquaporin-1 passively transports water into cell (Danio rerio)


name: p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Gallus gallus)


name: Opioid dissociates from MOR (Bos taurus)


name: (7Z)-octadecenoyl-CoA + cholesterol = cholesteryl (7Z)-octadecenoate + CoA


name: L-isoleucine + neocasomorphin-(1-5) => H2O + neocasomorphin


name: ATXN3 family cleave Ub chains (Danio rerio)


name: RHOA:GTP binds RHPN1 or RHPN2 (Homo sapiens)


name: CatSper Channel Mediated Calcium Transport (Bos taurus)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Bos taurus)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: p-STAT5A/B dissociates from the Growth Hormone receptor (Gallus gallus)


name: N-arachidonyl glycine receptor GPR18 binds N-arachidonyl glycine (Mus musculus)


name: MITF-M-dependent ATP6V1C1 gene expression (Homo sapiens)


name: Auto-ubiquitination of TRAF3 (Bos taurus)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Bos taurus)


name: PE is converted to PS by PTDSS2 (Danio rerio)


name: 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-2,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: eugenol + S-adenosyl-L-methionine => H(+) + O-methyleugenol + S-adenosyl-L-homocysteine


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + 2 succinate


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Homo sapiens)


name: glutathione + H(+) + hydrogen sulfide + ubiquinone-10 => S-sulfanylglutathione + ubiquinol-10


name: IGFBP2 binds IGF forming IGF:IGFBP2 (Sus scrofa)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Mus musculus)


name: (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + CO2 + CoA


name: (E)-alk-1-en-1-SO-peroxol => (Z)-alkanethial oxide


name: (2R,3S)-3-isopropylmalate + NAD(+) => 4-methyl-2-oxopentanoate + CO2 + NADH


name: SLC29A1 transports RBV from extracellular region to cytosol (Rattus norvegicus)


name: SUMOylation of TDG with SUMO1 (Danio rerio)


name: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) => 7,8-dihydroxykynurenate + H(+) + NADH


name: ALDH1A1 oxidises GA to DGA (Canis familiaris)


name: GNRHR binds chemical antagonists (Bos taurus)


name: ERCC8 (CSA) binds stalled RNA Pol II (Drosophila melanogaster)


name: beta-D-fructose 6-phosphate + NH4(+) => alpha-D-glucosamine 6-phosphate + H2O


name: ATP + H(+) + octanoate => diphosphate + octanoyl-AMP


name: ARFRP1 recruits ARL1 to the TGN (Rattus norvegicus)


name: Type B histone acetlytransferase complex acetylates histone H4 (Homo sapiens)


name: Pro-beta-NGF and mature beta-NGF are secreted (Xenopus tropicalis)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + AH2 + O2 => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + A + 2 H2O


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Dictyostelium discoideum)


name: HDACs deacetylate p-STAT3 dimers (Canis familiaris)


name: L-kynurenine + pyruvate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-alanine


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Bos taurus)


name: H2O + NAD(+) + quinoline-2,8-diol => H(+) + NADH + O2 + quinolin-2-ol


name: IRAK1 induces oligomerisation of TRAF6 (Drosophila melanogaster)


name: ATP + N-acetyl-D-glucosamine <=> ADP + H(+) + N-acetyl-D-glucosamine 6-phosphate


name: H(+) + N-acyl-15-methylhexadecasphinganine + NADPH + O2 => H2O + N-acyl-4-hydroxy-15-methylhexadecasphinganine + NADP(+)


name: acetyl-CoA + hexadecanoyl-CoA => 3-oxooctadecanoyl-CoA + CoA


name: HTR1 and 5A receptors can bind serotonin (Caenorhabditis elegans)


name: Cleavage of DFF45 (224) by caspase-3 (Sus scrofa)


name: ATP + CoA + octadecanoate = AMP + diphosphate + octadecanoyl-CoA


name: 2-oxoglutarate + O2 + validamycin A <=> CO2 + H(+) + succinate + validamycin B


name: (2E,6E)-farnesyl diphosphate + H2O => alpha-eudesmol + diphosphate


name: (2E)-geranyl diphosphate + H2O => (S)-linalool + diphosphate


name: neamine + UDP-alpha-D-kanosamine = H(+) + kanamycin B + UDP


name: Conjugation of SUMO1 to UBA2:SAE1 (Danio rerio)


name: n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate => n adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate + n H(+)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Bos taurus)


name: PIAS2-2 SUMOylates THRA with SUMO1 (Caenorhabditis elegans)


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Caenorhabditis elegans)


name: 7-oxocholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta,26-dihydroxycholest-5-en-7-one + H2O + 2 oxidized [adrenodoxin]


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Canis familiaris)


name: Activation of Protein Kinase C novel isoforms (Drosophila melanogaster)


name: butan-1-ol + 2 Fe(III)-[cytochrome c] = butanal + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: "1-butanol dehydrogenase (cytochrome c)"


name: H2O + nonane-4,6-dione => butanoate + H(+) + pentan-2-one


name: ATP(in) + UDP(out) <=> ATP(out) + UDP(in)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH


name: PEX16:PEX19:PEX3 dissociates (Homo sapiens)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycerol + H(+) + phosphoethanolamine


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + leukotriene D4 <=> glycine + leukotriene E4


name: miR-26A microRNAs bind PTEN mRNA (Homo sapiens)


name: (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + H2O + NAD(+) => (E)-2-((N-methylformamido) methylene)succinate + 3 H(+) + NADH


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Dictyostelium discoideum)


name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Homo sapiens)


name: SRXN1 reduces hyperoxidized PRDX1 dimer (Canis familiaris)


name: FAM20C phosphorylates FAM20C substrates (Bos taurus)


name: D-cysteine + H2O = H(+) + hydrogen sulfide + NH4(+) + pyruvate


name: PPARG binds PPARG agonists (Rattus norvegicus)


name: (3S)-3-hydroxypentanoyl-CoA + H2O <=> (3S)-3-hydroxypentanoate + CoA + H(+)


name: an adenosine in tRNA + S-adenosyl-L-methionine <=> an N(1)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine


name: 14-3-3 proteins bind AKT-phosphorylated FOXO1 (Bos taurus)


name: UNC119B binds myristoylated proteins (Bos taurus)


name: Dephosphorylation of p107 (RBL1) by PP2A (Dictyostelium discoideum)


name: USP9X binds Ub:PEX5L (Dictyostelium discoideum)


name: RAF phosphorylates MAP2K dimer (Mus musculus)


name: COPI vesicle uncoating at the ER (Rattus norvegicus)


name: Formation of MSH2:MSH6 Complex (Bos taurus)


name: (2E,6E,10E)-geranylgeranyl diphosphate => delta-araneosene + diphosphate


name: D-glucuronate + H(+) => D-glucurono-6,2-lactone + H2O


name: Defective GYG1 is not autoglucosyolated (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(9Z-octadecenoyl) ethanolamine => H2O + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: nitric oxide dioxygenase NAD(P)H activity


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Dictyostelium discoideum)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-phenylalanine => H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-phenylalanine


name: 25-hydroxyvitamin D3 sulfate(out) + n H(+)(out) <=> 25-hydroxyvitamin D3 sulfate(in) + n H(+)(in)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Sus scrofa)


name: SGT1:HSP90 binds inactive NLRP3 (Danio rerio)


name: a ubiquinol + 2 H(+)(in) + nitrate = a ubiquinone + 2 H(+)(out) + H2O + nitrite


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-3-octadecanoyl-sn-glycerol + H(+)


name: NGF binding to p75NTR inactivates RHOA (Xenopus tropicalis)


name: alpha-D-glucose 6-phosphate <=> beta-D-glucose 6-phosphate


name: a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Schizosaccharomyces pombe)


name: ATP + chenodeoxycholate + CoA => AMP + chenodeoxycholoyl-CoA + diphosphate


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Rattus norvegicus)


name: H(+) + L-glutamyl-tRNA(Glu) + NADPH => (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu)


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Caenorhabditis elegans)


name: (S)-columbianetin + O2 + reduced [NADPH--hemoprotein reductase] => acetone + angelicin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: anthraniloyl-CoA + H(+) + malonyl-CoA <=> (2-aminobenzoyl)acetyl-CoA + CO2 + CoA


name: CSN polymer binds CaPO4 (Canis familiaris)


name: SPRY2 translocates to the plasma membrane (Rattus norvegicus)


name: IKBA is phosphorylated by Phospho IKKB kinase (Homo sapiens)


name: Exocytosis of platelet dense granule content (Schizosaccharomyces pombe)


name: estrone + PAPS => estrone 3-sulfate + PAP (Rattus norvegicus)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O <=> a 1-acyl-sn-glycero-3-phosphate + H(+) + L-serine


name: 6-tuliposide B = D-glucose + tulipalin B


name: Phosphorylation of NTAL by p-SYK/Lyn (Rattus norvegicus)


name: ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC (Danio rerio)


name: O-glycosylation of 3a is terminated (Homo sapiens)


name: Arachidonate is hydroxylated to 16-HETE by CYP(1) (Rattus norvegicus)


name: NADP(+) + xylitol <=> H(+) + L-xylulose + NADPH


name: methionyl-initiator methionine tRNA binding


name: PLC beta-mediated PIP2 hydrolysis (Mus musculus)


name: Recruitment of GRB2 to p-PTK2 (Sus scrofa)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Sus scrofa)


name: (E)-feruloyl-CoA + H2O <=> acetyl-CoA + vanillin


name: ATM phosphorylates WHSC1 (Schizosaccharomyces pombe)


name: LIPA hydrolyses sterol esters to sterols and fatty acids (Mus musculus)


name: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+)


name: (E)-gamma-bisabolene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 2-methylpropanal + H(+) + methylamine + NADH => H2O + N-methyl-2-methylpropanamine + NAD(+)


name: XPC binds RAD23 and CETN2 (Canis familiaris)


name: ADP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + H(+) + phosphate => ATP + C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine


name: MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Mus musculus)


name: alpha-D-mannose derivative + UDP-alpha-D-glucose <=> 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H(+) + UMP


name: acetyl-CoA + trans-glutaconate = (2E)-glutaconyl-CoA + acetate


name: Androgens binds AR (in the HSP90 chaperone complex) (Gallus gallus)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Sus scrofa)


name: PIR oxygenates quercetin (Dictyostelium discoideum)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Canis familiaris)


name: a 2-hydroxycarbonyl + H(+) + NADPH => an L-glycol + NADP(+)


name: TP53 binds STK11 and NUAK1 (Mus musculus)


name: ESTG binds ESR2:chaperone complex (Danio rerio)


name: FMNH2 + N-acetyl-S-methyl-L-cysteine + O2 = (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H(+) + H2O


name: CARKD dehydrates S-NAD(P)HX to NADPH (Drosophila melanogaster)


name: UDP-alpha-D-galactose(in) + UMP(out) = UDP-alpha-D-galactose(out) + UMP(in)


name: CANX dissociates from IL27:EBI3 (Sus scrofa)


name: H2O + tetradecanoyl-CoA = CoA + H(+) + tetradecanoate


name: a polyvinyl alcohol + n O2 = an oxidized polyvinyl alcohol + n H2O2


name: 3-oxodocosanoyl-CoA + H(+) + NADH => (3R)-hydroxydocosanoyl-CoA + NAD(+)


name: benzaldehyde + hydrogen cyanide => (S)-mandelonitrile


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Sus scrofa)


name: adenosine 3',5'-bisphosphate + 2 H(+) + hexanoyl-4'-phosphopantetheine => H2O + hexanoyl-CoA


name: furfural + H2O + NAD(+) = 2-furoate + 2 H(+) + NADH


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA => (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA


name: a 2-hydroxy-3-methyl fatty acyl-CoA => a 2-methyl-branched fatty aldehyde + formyl-CoA


name: GTSE1 promotes translocation of TP53 to the cytosol (Homo sapiens)


name: CBL ubiquitinates FRS2 and FGFR1 (Rattus norvegicus)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Xenopus tropicalis)


name: CTP(out) + GMP(in) <=> CTP(in) + GMP(out)


name: PINK1 is autophosphorylated (Caenorhabditis elegans)


name: p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Canis familiaris)


name: NADP(+) + propane-1,3-diol = 3-hydroxypropanal + H(+) + NADPH


name: S100A1 binds TLR4:LY96 (Rattus norvegicus)


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Rattus norvegicus)


name: STING ubiquitination by TRIM32 or TRIM56 (Sus scrofa)


name: a propanoate ester + H2O => an aliphatic alcohol + H(+) + propanoate


name: a globoside Gb3Cer + UDP-N-acetyl-alpha-D-galactosamine = a globoside Gb4Cer + H(+) + UDP


name: HS-GAGs translocate to the lysosome for degradation (Canis familiaris)


name: a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + H(+) + UDP => a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine


name: 4-chlorobenzoyl-CoA + H2O <=> 4-hydroxybenzoyl-CoA + chloride + H(+)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + CoA


name: MHC class II antigen processing (Bos taurus)


name: botB LC cleaves target cell VAMP2 (Homo sapiens)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Gallus gallus)


name: Phosphorylation of BRCA1-A complex at multiple sites by ATM (Bos taurus)


name: RAC2 translocates to the ER membrane (Xenopus tropicalis)


name: hydroxylamine + O2 = H(+) + H2O + nitrite


name: EGFR binds EGF ligand (Rattus norvegicus)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Homo sapiens)


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Gallus gallus)


name: Phosphorylation of MEF2 proteins by p38 (Schizosaccharomyces pombe)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Schizosaccharomyces pombe)


name: CPTP transports C1P from plasma membrane to Golgi membrane (Drosophila melanogaster)


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Canis familiaris)


name: limonene-1,2-diol => H2O + limonene 1,2-epoxide


name: 4alpha-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-hydroxymethylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: PSMD5 and PSMD2 bind PSMC2:PSMC1 (Dictyostelium discoideum)


name: GPX5,6 reduce H2O2 to H2O (Canis familiaris)


name: RAC2 binds effectors at the phagocytic vesicle membrane (Mus musculus)


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Sus scrofa)


name: 2 H(+)(in) + H2 + menaquinone-8 => 2 H(+)(out) + menaquinol-8


name: H(+) + H2O + N(6)-methyl-AMP <=> IMP + methylamine


name: HCCS inserts heme into cytochrome c (Schizosaccharomyces pombe)


name: (9Z,12Z)-octadecadienoate + O2 <=> (2R,9Z,12Z)-2-hydroperoxyoctadecadienoate


name: Activation of Calcineurin (Caenorhabditis elegans)


name: PLC activating G protein-coupled glutamate receptor activity


name: 4 (R)-lactate + 8 ATP + 4 L-leucine + 4 S-adenosyl-L-methionine = 8 AMP + 8 diphosphate + 8 H(+) + PF1022F + 4 S-adenosyl-L-homocysteine


name: H2O + L-rhamnono-1,4-lactone => H(+) + L-rhamnonate


name: CHRM4 binds CHRM4 antagonists (Canis familiaris)


name: chlorophyll b + H(+) + NADPH => 7(1)-hydroxychlorophyll a + NADP(+)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: fumarate + H(+) + NADH => NAD(+) + succinate


name: chlorohydroquinone + 2 glutathione = chloride + glutathione disulfide + H(+) + hydroquinone


name: (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP


name: H(+) + NADPH + undecanal => NADP(+) + undecan-1-ol


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Mus musculus)


name: Ubiquitinated TP53 translocates to the cytosol (Rattus norvegicus)


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Mus musculus)


name: NRF1:p-PPARGC1A, NRF2 bind the TFAM promoter (Homo sapiens)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Canis familiaris)


name: (R)-pantothenate + H2O => (R)-pantoate + beta-alanine


name: D-glucose + N-acyl-15-methylhexadecasphing-4-enine => H2O + N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine


name: a long-chain 3-oxo-fatty acyl-CoA + H(+) + NADH => a long-chain (3R)-hydroxyacyl-CoA + NAD(+)


name: C1-Inh binds and inactivates C1r, C1s (Mus musculus)


name: 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + ATP + CoA = 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA + AMP + diphosphate


name: AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)


name: Formation of MSH1:PMS2 Complex (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylethanolamine = 2-(acylamino)ethyl fatty acid + a 1-acyl-sn-glycero-3-phosphocholine


name: (E)-sinapaldehyde + CoA + NADP(+) => (E)-sinapoyl-CoA + H(+) + NADPH


name: H2O + pravastatin lactone = H(+) + pravastatin


name: Phosphorylation of CD28 (Canis familiaris)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose => a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + H(+) + UDP


name: H2O2 + 2 L-ascorbate <=> 2 H2O + 2 monodehydro-L-ascorbate radical


name: RUNX3 translocates to the nucleus (Canis familiaris)


name: MDM2 ubiquitinates phosphorylated MDM4 (Danio rerio)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H2O <=> an N-acylsphing-4-enine + D-galactose


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Homo sapiens)


name: NOTCH4 gene transcription is inhibited by RUNX1 (Homo sapiens)


name: NAD(+) + perillyl alcohol => H(+) + NADH + perillyl aldehyde


name: an N-acyl-sphingoid base + D-galactose => a D-galactosylceramide + H2O


name: (5R)-carbapenem-3-carboxylate + CO2 + H2O + succinate => (3S,5S)-carbapenam-3-caboxylate + 2-oxoglutarate + O2


name: FOLR2 transports FOLA from extracellular region to cytosol (Sus scrofa)


name: 5a,11a-dehydrooxytetracycline + H2O + NADP(+) => 5a,11a-dehydrotetracycline + H(+) + NADPH + O2


name: PE is converted to PS by PTDSS2 (Sus scrofa)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Danio rerio)


name: PAK1,2,3 phosphorylates MAPK6,4 (Sus scrofa)


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate = 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: (9Z)-hexadecenoyl-[ACP] + L-lysyl-[protein] = H(+) + holo-[ACP] + N(6)-[(9Z)-hexadecenoyl]-L-lysyl-[protein]


name: Activation of RAC1 by the PXN:CRK complex (Homo sapiens)


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Danio rerio)


name: H2O + ilicicolin A epoxide + NADP(+) => H(+) + ilicicolin A + NADPH + O2


name: acetyl-CoA + AH2 + 3 malonyl-CoA + 3 S-adenosyl-L-methionine => A + 3 CO2 + 4 CoA + fumigermin + H2O + 3 S-adenosyl-L-homocysteine


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Danio rerio)


name: HUT2 and HUT11 mediate urea transport in kidney and erythrocytes respectively (Rattus norvegicus)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA


name: 4-hydroxy-6-(11-methyldodecyl)-pyran-2-one + 2 CO2 + 3 CoA => 12-methyltridecanoyl-CoA + 2 H(+) + 2 malonyl-CoA


name: P4 bind PGR (in the HSP90 chaperone complex) (Danio rerio)


name: PC is converted to PS by PTDSS1 (Mus musculus)


name: 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecenyl)-glycerol


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Canis familiaris)


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Sus scrofa)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Drosophila melanogaster)


name: Activation of Cdc42 by pVav1 (Homo sapiens)


name: Active G alpha (i)–i1/i2/i3 binds RGS proteins (Canis familiaris)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains (Canis familiaris)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H(+) + O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-seryl-[protein] + UDP


name: lithocholate + UDP-alpha-D-glucuronate => lithocholoyl-24-O-(beta-D-glucuronate) + UDP


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Canis familiaris)


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Sus scrofa)


name: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H(+)


name: glycocholate + L-arginine => glycine + L-arginocholate


name: H2O + N(1)-acetylspermine + O2 => 3-aminopropanal + H2O2 + N(1)-acetylspermidine


name: 6-amino-2-oxohexanoate = Delta(1)-piperideine-2-carboxylate + H2O


name: GDP-beta-L-fucose + methyl 8-{[beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosamyl]oxy}nonanoate <=> GDP + H(+) + methyl 8-{[beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: RUNX2 binds SMAD1 in the nucleus (Homo sapiens)


name: POU3F1 and ZNF521 bind the PAX6 gene (Homo sapiens)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Drosophila melanogaster)


name: Myoglobin:oxygen dissociates (Rattus norvegicus)


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] => akuammicine + formate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: [N-(2,3-dihydroxybenzoyl)-L-seryl]2-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine + H(+) => H2O + monoglucosyl-enterobactin


name: Nephrin binds NCK (Drosophila melanogaster)


name: a primary alcohol + N,N-dimethyl-4-nitrosoaniline => 4-(hydroxylamino)-N,N-dimethylaniline + an aldehyde


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Mus musculus)


name: (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate => (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = 3-hydroxy-3-methyl-2-oxobutanoate + H(+) + NADPH


name: H(+) + prephenate <=> 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2


name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] (Homo sapiens)


name: 4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH


name: Aquaporin-1 passively transports water into cell (Sus scrofa)


name: 3-oxopropanoate + CoA + NAD(+) <=> acetyl-CoA + CO2 + NADH


name: ethanethiol + NH4(+) + pyruvate => H2O + S-ethyl-L-cysteine


name: JNK phosphorylates BIM, BAD and other targets (Homo sapiens)


name: Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 (Gallus gallus)


name: HTN1,HTN3 or HTN5 binds the bacterial anionic surface  (Homo sapiens)


name: 16alpha-hydroxyestrone + UDP-alpha-D-glucuronate <=> 16alpha-hydroxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: SOS mediated nucleotide exchange of RAS (SHC) (Sus scrofa)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)


name: BP230 is recruited to the hemidesmosome (Sus scrofa)


name: 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + H(+) + UDP => H2O + UDP-N,N'-diacetylbacillosamine


name: (R)-3-(4-hydroxyphenyl)lactoyl-CoA => (E)-4-coumaroyl-CoA + H2O


name: hexanoyl-CoA + NADP(+) => (2E)-hexenoyl-CoA + H(+) + NADPH


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Mus musculus)


name: 2 (R)-3-hydroxybutanoate + H(+) => (3R)-hydroxybutanoate dimer + H2O


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->6)-N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + H(+) + UDP => 3-O-[N-acetyl-alpha-D-glucosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: AMP binds to gamma subunit of AMP kinase heterotrimer (Mus musculus)


name: Phosphorylation of PLCgamma by PDGFR (Gallus gallus)


name: Expression of TRIB3 in response to stress (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(beta-D-glucuronate) = 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: 2,5-dihydroxybenzoyl-CoA + H2O = 2,5-dihydroxybenzoate + CoA + H(+)


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Rattus norvegicus)


name: (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + H(+) + oxidized [electron-transfer flavoprotein] + sarcosine => (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + glycine + reduced [electron-transfer flavoprotein]


name: (S)-2-methyl-3-oxopropanoate + CoA + NAD(+) => CO2 + NADH + propanoyl-CoA


name: ALAS condenses SUCC-CoA and Gly to form dALA (Bos taurus)


name: H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate


name: 1,2-dihexadecanoyl-sn-glycero-3-CDP + 1D-myo-inositol 3-phosphate <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)


name: 3''-dehydroisovitexin + H2O2 => isovitexin + O2


name: a monocarboxylic acid amide + H2O <=> a monocarboxylate + NH4(+)


name: ATP + L-erythrulose <=> ADP + H(+) + L-erythrulose 1-phosphate


name: 2-oxo-AMP + diphosphate + H(+) => 2-oxo-ATP + H2O


name: SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Xenopus tropicalis)


name: L-iditol 2-dehydrogenase (NAD+) activity


name: NH4(+) + urea-1,3-dicarboxylate => 1-carboxybiuret + H2O


name: RHOD GAPs stimulate RHOD GTPase activity (Xenopus tropicalis)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Gallus gallus)


name: 3 H(+) + phosphocholine + 3 S-adenosyl-L-homocysteine => phosphoethanolamine + 3 S-adenosyl-L-methionine


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Canis familiaris)


name: (S)-beta-macrocarpene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + zealexin A1


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: ALDH3A2-1 oxidises HD2NAL to PALM (Danio rerio)


name: Defective SLC3A1 (in SLC7A9:SLC3A1) does not exchange L-Arg, CySS-, L-Lys for L-Leu (Homo sapiens)


name: USP13 and OTUD3 deubiquitinate PTEN (Schizosaccharomyces pombe)


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Dictyostelium discoideum)


name: an 11beta-hydroxysteroid + NAD(+) => an 11-oxosteroid + H(+) + NADH


name: (n-1) H2O + RNA(n) = n a ribonucleoside 5'-phosphate + n H(+)


name: BRCA1 forms a heterodimer with BARD1 (Sus scrofa)


name: SFN dimer binds CDK1 and CCNB1 (Xenopus tropicalis)


name: (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H(+) + UDP => (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + UDP-alpha-D-glucose


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] = (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoyl-CoA + sn-glycero-3-phosphoethanolamine = (9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: bromochloromethane + H2O <=> bromide + chloride + formaldehyde + 2 H(+)


name: G beta-gamma complex and PIP3 recruit BTK to membrane (Bos taurus)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Gallus gallus)


name: BRCA1 is recruited to unsynapsed regions (Homo sapiens)


name: VMAT1/2 can mediate the transport of biogenic amines (Rattus norvegicus)


name: PLK1 phosphorylates NUDC (Caenorhabditis elegans)


name: a very long-chain fatty acid(out) + ADP + H(+) + phosphate => a very long-chain fatty acid(in) + ATP + H2O


name: ECI2 isomerizes 3Z-enoyl-CoA to 2E-enoyl-CoA (Rattus norvegicus)


name: Ferriheme is transferred from Albumin to Hemopexin (Mus musculus)


name: a medium-chain fatty acyl-AMP + holo-[ACP] => a medium-chain fatty acyl-[ACP] + AMP + H(+)


name: 2-dehydro-3-deoxy-L-fuconate + NAD(+) = 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH


name: AMP + H(+) + nebramycin 5' => carbamoyl adenylate + tobramycin


name: THEM86B hydrolyses PMCHO, PMETAM (Dictyostelium discoideum)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Homo sapiens)


name: p-Y701-STAT1 dimer translocates from the cytosol to the nucleus (Caenorhabditis elegans)


name: NLK translocates to nucleus (Canis familiaris)


name: ATP + CoA + pentanoate => AMP + diphosphate + pentanoyl-CoA


name: SPAM1 Binds Hyaluronic Acid (Canis familiaris)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Danio rerio)


name: vitamin-K-epoxide reductase (warfarin-insensitive) activity


name: HSD11B1 hydrogenates PREDN to PREDL in hepatic cell (Sus scrofa)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Saccharomyces cerevisiae)


name: H2O + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1,2-diacyl-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)


name: Translocation of Ezrin to plasma membrane (Danio rerio)


name: beta-muricholoyl-CoA + lithocholate => beta-muricholate + lithocholoyl-CoA


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Canis familiaris)


name: ULK complex translocates to the ER (Dictyostelium discoideum)


name: glycerol + NADP(+) <=> D-glyceraldehyde + H(+) + NADPH


name: (+)-copalyl diphosphate => diphosphate + isopimara-8(14),15-diene


name: Integrator complex processes the 3' end of snRNA (Danio rerio)


name: H2O + N(6)-hexadecanoyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-hexadecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Mus musculus)


name: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + ADP + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate = 3-devinyl-3-(1-hydroxyethyl)chlorophyllide a + ATP + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin]


name: Aquaporins passively transport urea into cells (Bos taurus)


name: I(1,4,5)P3 transports from the cytosol to the nucleus (Homo sapiens)


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Dictyostelium discoideum)


name: Release of the SLBP independent Histone mRNA from the NPC (Homo sapiens)


name: 13-cis-retinol + a fatty acyl-CoA <=> 13-cis-retinyl ester + CoA


name: (2Z,6Z)-farnesyl diphosphate => alpha-acoradiene + diphosphate


name: 4 H2O + 2 L-citrulline + 3 NADP(+) + 2 nitric oxide => H(+) + 2 L-arginine + 3 NADPH + 4 O2


name: CASP9 is phosphorylated at T412 (Danio rerio)


name: The orphan QRFP receptor can bind neuropeptide QRFP (Bos taurus)


name: a 5'-end diphospho-adenosine in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein] <=> a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + L-lysyl-[protein]


name: acetylglucosamine-inositol-phosphate is dephosphorylated (Mycobacterium tuberculosis)


name: (2E,6E)-farnesyl diphosphate = alpha-selinene + diphosphate


name: (2R,3S,4S)-leucocyanidin + 2-oxoglutarate + O2 = (4S)-2,3-dehydroleucocyanidin + CO2 + H(+) + H2O + succinate


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Canis familiaris)


name: PGG2 is reduced to PGH2 by PTGS1 (Xenopus tropicalis)


name: CMP-5'-(3-aminopropyl)phosphonate + NADPH + O2 => CMP-5'-(N-hydroxy-3-aminopropyl)phosphonate + H2O + NADP(+)


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA <=> an acyl-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + holo-[ACP]


name: (S)-2-ureidoglycine + H2O = glyoxylate + NH4(+) + urea


name: HBEGF-bound EGFR forms a heterodimer with GPNMB (Mus musculus)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Plasmodium falciparum)


name: fluoroacetate + H2O => fluoride + glycolate + H(+)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Rattus norvegicus)


name: Digestion of diacylglycerols by extracellular PTL:colipase (Mus musculus)


name: a ganglioside GM1 + GDP-beta-L-fucose => a ganglioside Fuc-GM1 + GDP + H(+)


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Drosophila melanogaster)


name: n H(+)(in) + pregnenolone sulfate(in) => n H(+)(out) + pregnenolone sulfate(out)


name: H2O + sitosteryl 3-beta-D-glucoside = D-glucose + sitosterol


name: RAS guanyl nucleotide exchange by SOS1 bound to GRB2, SCH1-2 and MET (Rattus norvegicus)


name: plastid PEP RNA polymerase core enzyme binding


name: ABC-type fatty-acyl-CoA transporter activity


name: (R)-dihydrolipoate + ATP + L-lysyl-[lipoyl-carrier protein] => AMP + diphosphate + H(+) + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein]


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Sus scrofa)


name: 2 H(+) + hexadecanoyl-CoA + 2 malonyl-CoA <=> 4-hydroxy-6-pentadecylpyran-2-one + 2 CO2 + 3 CoA


name: 3-hydroxypropanoyl-CoA + ADP + phosphate => 3-hydroxypropanoate + ATP + CoA


name: 1-O-hexadecyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH => 1-O-hexadecyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: PLC gamma 2-mediated PIP2 hydrolysis (Xenopus tropicalis)


name: STUB1 ubiquitinates RIPK3 at K55, K363 (Bos taurus)


name: (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate => (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA = an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA + holo-[ACP]


name: ADP-D-ribose + H(+) + nicotinamide => H2O + NAD(+)


name: 3''-dehydroisoorientin => 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Caenorhabditis elegans)


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Sus scrofa)


name: FN3K phosphorylates ketosamines (Xenopus tropicalis)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Drosophila melanogaster)


name: (R)-acetoin + H(+) + NADH => (R,S)-butane-2,3-diol + NAD(+)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA


name: DEK binds TFAP2A homodimers (Gallus gallus)


name: cyclobutadithymidine in DNA => a thymidine dimer in DNA


name: Bile salts dissociate from FABP6 (Rattus norvegicus)


name: 2 Fe(III)-[cytochrome b5] + H2O + N-hexacosanoyl-(4R)-hydroxysphinganine => 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-hexacosanoylsphinganine + O2


name: TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)


name: (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate = di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate


name: RAC1 binds effectors at the plasma membrane (Drosophila melanogaster)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Gallus gallus)


name: miR-21 nonendonucleolytic RISC binds PTEN mRNA (Homo sapiens)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Rattus norvegicus)


name: H(+) + S-methyl-5'-thioadenosine + thermospermine => S-adenosyl 3-(methylsulfanyl)propylamine + spermidine


name: phospholipid-hydroperoxide glutathione peroxidase activity


name: Serum albumin binds 2-lysophosphatidylcholine (Bos taurus)


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Gallus gallus)


name: (2E)-decenedioyl-CoA + H2O => (3S)-hydroxydecanedioyl-CoA


name: JAK2 phosphorylation of IRS-1/2 (Homo sapiens)


name: acetyl-CoA + N-terminal L-cysteinyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-cysteinyl-[protein]


name: 5-phosphomethyl-dUMP in DNA + putrescine <=> 5-N(alpha)-putrescinyl-dTMP in DNA + phosphate


name: STAT4 binds IL12RB2:IL12RB2 (Xenopus tropicalis)


name: Phosphorylation of TEC kinases by p-SYK (Homo sapiens)


name: (2E)-decenoyl-CoA + H(+) + NADPH => decanoyl-CoA + NADP(+)


name: 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH => 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+)


name: TCF:Beta-catenin binds SOX proteins (Mus musculus)


name: Myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Sus scrofa)