name: alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucuronate <=> beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: ATR phosphorylates TP53 (Drosophila melanogaster)


name: high-affinity zinc transmembrane transporter activity


name: 3-methoxy-4',5-dihydroxy-trans-stilbene + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + trans-resveratrol


name: H2O + N(1)-acetylspermine => acetate + spermine


name: RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Mus musculus)


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Caenorhabditis elegans)


name: polyvinyl alcohol dehydrogenase (cytochrome) activity


name: AcK-NFE2L2 binds the GCLC gene (Homo sapiens)


name: adenosine 3'-diphosphate,5'-diphosphate + AMP => ADP + ATP


name: Cyclin D:CDK4/6 phosphorylates RB1 and prevents RB1 binding to E2F1/2/3:DP1/2 complexes (Gallus gallus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ORC1 translocates to the nucleus (Gallus gallus)


name: 3'-phosphoadenylyl sulfate + a ganglioside GM1b <=> adenosine 3',5'-bisphosphate + an 8-O-sulfo-ganglioside GM1b + H(+)


name: n H(+)(out) + spermine(in) <=> n H(+)(in) + spermine(out)


name: Release of PLCG from FCGR (Gallus gallus)


name: Prolactin receptor ligands bind the prolactin receptor (Rattus norvegicus)


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Xenopus tropicalis)


name: Activated ATM phosphorylates ABL1 (Homo sapiens)


name: VTN binds Plasminogen activator inhibitor- 1 (Sus scrofa)


name: (1S,4S)-dihydrocarvone + H(+) + NADH => (1S,2R,4S)-neodihydrocarveol + NAD(+)


name: (S)-lactate + ATP + H(+) <=> (S)-lactoyl-AMP + diphosphate


name: adenosine 3',5'-bisphosphate + H(+) + holo-[D-alanyl-carrier protein] => apo-[D-alanyl-carrier protein] + CoA


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)


name: inosine(in) + 2 Na(+)(in) => inosine(out) + 2 Na(+)(out)


name: KDM6B binds iron (Caenorhabditis elegans)


name: p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Canis familiaris)


name: TRPV1 binds TRPV1 agonists (Danio rerio)


name: Formation of the SCF-FBXL7 complex (Bos taurus)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Mus musculus)


name: RNF41 ubiquitinates activated ERBB3 (Gallus gallus)


name: Squalene is oxidized to its epoxide (Danio rerio)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Gallus gallus)


name: SLC6A6-mediated uptake of taurine and beta-alanine (Bos taurus)


name: 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O <=> 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde


name: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O = 2-formylglutarate + NH4(+)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Homo sapiens)


name: Rnd1 interacts with Plexin-B1:Sema4D (Bos taurus)


name: 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C (Mus musculus)


name: PP2A dephosphorylates BANF1 (Rattus norvegicus)


name: (2-aminobenzyl)malonyl-CoA + H(+) + O2 => (E)-2-aminocinnamoyl-CoA + CO2 + H2O2


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: H2O + N(6)-acetyl-L-lysyl-[protein] + O2 = (S)-2-amino-6-oxohexanoyl-[protein] + acetamide + H2O2


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Gallus gallus)


name: L-alanine(out) + L-cysteine(in) => L-alanine(in) + L-cysteine(out)


name: Formation of the CE:GMP intermediate complex (Sus scrofa)


name: (1S,5S)-beta-pinene + diphosphate => (2E)-geranyl diphosphate


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Mus musculus)


name: beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose <=> alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP + H(+)


name: hexadecanoyl-CoA + sn-glycerol 3-phosphocholine <=> CoA + hexadecanoyl-sn-glycero-3-phosphocholine


name: GSDMD (1-275) binds PIPs (Canis familiaris)


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Canis familiaris)


name: 17alpha-ethynylestradiol + 3'-phosphoadenylyl sulfate => 17alpha-ethynylestradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: UROD decarboxylates URO1 to COPRO1 (Homo sapiens)


name: Calmodulin dissociates KRAS4B from the plasma membrane (Rattus norvegicus)


name: a ganglioside Ac-O-7-GT3 => a ganglioside Ac-O-8-GT3


name: AKT-phosphorylated FOXO3 translocates to cytosol (Bos taurus)


name: GMPS dimer transforms 6TXMP to 6TGMP (Gallus gallus)


name: NPY gene expression is stimulated by FOXO1 (Homo sapiens)


name: PRKN binds p-S-Ub:MOM proteins (Drosophila melanogaster)


name: 2-oxoglutaramate + L-methionine => 4-methylsulfanyl-2-oxobutanoate + L-glutamine


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Mus musculus)


name: adenylyl MoO2(OH)-molybdopterin cofactor + H2O => AMP + 2 H(+) + Mo-molybdopterin


name: ST6GAL1,2 transfer Neu5Ac to terminal Gal (alpha-2,6 link) (Bos taurus)


name: carnosine + S-adenosyl-L-methionine = anserine + H(+) + S-adenosyl-L-homocysteine


name: Furin cleaves pro-factor IX to factor IX (Mus musculus)


name: miltiradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = 11-oxomiltiradiene + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: trans-2-enoyl-CoA reductase (NADH) activity


name: demethyldeoxyspectinabilin + S-adenosyl-L-methionine => deoxyspectinabilin + S-adenosyl-L-homocysteine


name: aculene D + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase] => asperaculane G + O2 + reduced [NADPH--hemoprotein reductase]


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: RIC1-RGP1 exchanges GTP for GDP on RAB6 (Caenorhabditis elegans)


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Mus musculus)


name: acetyl-CoA + ergosta-5,7,22,24(28)-tetraen-3beta-ol => CoA + ergosta-5,7,22,24(28)-tetraen-3beta-yl acetate


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Danio rerio)


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: HRASLS transfer acyl group from PC to PE to form NAPE (Xenopus tropicalis)


name: (R)-acetoin + NAD(+) => diacetyl + H(+) + NADH


name: Cytosolic TIM is degraded by the 26S proteasome (Drosophila melanogaster)


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Caenorhabditis elegans)


name: CTP(in) + UDP(out) => CTP(out) + UDP(in)


name: 2 L-ascorbate + NAD(+) => H(+) + 2 monodehydro-L-ascorbate radical + NADH


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Mus musculus)


name: PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Homo sapiens)


name: a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose <=> a globoside GalGb4Cer (d18:1(4E)) + H(+) + UDP


name: 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: D-cellohexaono-1,5-lactone + H2O = D-cellohexaonate + H(+)


name: T1R2/T1R3 dimer is a sweet taste receptor (Homo sapiens)


name: H(+) + S-adenosyl-L-homocysteine + S-methyl-L-cysteinyl-[protein] => L-cysteinyl-[protein] + S-adenosyl-L-methionine


name: 5-C(alpha)-glycyl-dTMP in DNA + H(+) = 5-aminoethyl-dUMP in DNA + CO2


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) <=> (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH


name: alpha-ketoglutarate transmembrane transporter activity


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Homo sapiens)


name: Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)


name: 4-methyl-2-oxopentanoate + L-glutamate => 2-oxoglutarate + L-leucine


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + isopentadecanoyl-CoA + L-serine <=> 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA


name: Expression of ZIC1 in the neural plate border (Homo sapiens)


name: Dual mechanism MAPK inhibitors bind MAPKs (Homo sapiens)


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Bos taurus)


name: Formation of the closed pre-initiation complex (Dictyostelium discoideum)


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Dictyostelium discoideum)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O


name: D-xylono-1,4-lactone + H(+) + NADPH => D-xylofuranose + NADP(+)


name: 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Sus scrofa)


name: (2-aminophenyl)succinate + succinyl-CoA <=> 2-(2-aminophenyl)succinyl-CoA + succinate


name: Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Bos taurus)


name: estrone 3-sulfate(in) + propanoate(out) => estrone 3-sulfate(out) + propanoate(in)


name: P4 bind PGR (in the HSP90 chaperone complex) (Bos taurus)


name: ANGPTL8 binds ANGPTL3 (Canis familiaris)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = diphosphate + hydropyrenol


name: ent-kaur-16-en-19-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => ent-kaur-16-ene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: menadiol + 2 O2 => 2 H(+) + menadione + 2 superoxide


name: 2-hexyl-5-(5-hydroxypentyl)resorcinol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-hexyl-5-pentylresorcinol + O2 + reduced [NADPH--hemoprotein reductase]


name: dodecanoyl-[ACP] + H(+) + malonyl-[ACP] <=> 3-oxotetradecanoyl-[ACP] + CO2 + holo-[ACP]


name: THTPA:Mg2+ hydrolyzes ThTP to TDP (Xenopus tropicalis)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Homo sapiens)


name: [DsbB protein]-dithiol + a quinone => [DsbB protein]-disulfide + a quinol


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + H(+) <=> 2-GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane


name: 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate](n)


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: ADP + H(+) + sulfate => adenosine 5'-phosphosulfate + phosphate


name: a 5'-end phospho-ribonucleoside in snoRNA + H(+) + NAD(+) => a 5'-end NAD(+)-phospho-ribonucleoside in snoRNA + H2O


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 translocates from cytosol to nucleoplasm (Sus scrofa)


name: dehydro-L-arabinono-1,4-lactone + H(+) + H2O2 => L-xylono-1,4-lactone + O2


name: (E)-5-hydroxyferuloyl-CoA + S-adenosyl-L-methionine <=> (E)-sinapoyl-CoA + H(+) + S-adenosyl-L-homocysteine


name: 2 2-oxoglutarate + 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 O2 = 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 CO2 + H2O + 2 succinate


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Gallus gallus)


name: alliin <=> 2-aminoprop-2-enoate + allylsulfenate


name: chloride(out) + dopamine(out) + Na(+)(out) => chloride(in) + dopamine(in) + Na(+)(in)


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate


name: a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate => a ganglioside GD1a + CMP + H(+)


name: PTEN undergoes monoubiquitination (Canis familiaris)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Saccharomyces cerevisiae)


name: SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Homo sapiens)


name: RASA1 stimulates RAS GTPase activity (Homo sapiens)


name: DBT transfers BCAA to CoA (Mus musculus)


name: Urotensin-2 receptor binds urotensin-2 and 2B (Gallus gallus)


name: 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-glutamate => 2-oxoglutarate + 3-hydroxy-L-kynurenine


name: formyl-CoA + succinate => formate + succinyl-CoA


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Saccharomyces cerevisiae)


name: 4-methylsulfanyl-2-oxobutanoate + acetyl-CoA + H2O => 2-(2-methylsulfanyl)ethylmalate + CoA + H(+)


name: calcitriol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 1alpha,23S,25-trihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H(+) + NADPH => (23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+)


name: (2E)-dodecenedioyl-CoA + H2O <=> (3S)-hydroxydodecanedioyl-CoA


name: H(+) + hexan-3-one + NADPH + O2 <=> ethyl butanoate + H2O + NADP(+)


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Bos taurus)


name: FAICAR => IMP + H2O (Dictyostelium discoideum)


name: L-citrulline + methylamine => H2O + N(omega)-methyl-L-arginine


name: Spontaneous hydrolysis of C3 thioester (Gallus gallus)


name: MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin (Mus musculus)


name: Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Rattus norvegicus)


name: HMGCR dimer reduces bHMG-CoA to MVA (Sus scrofa)


name: 2-hydroxy-2-methylpropanenitrile = acetone + hydrogen cyanide


name: (R)-carnitine + crotonobetainyl-CoA => (R)-carnitinyl-CoA + crotonobetaine


name: Cho is acetylated to AcCho by CHAT (Mus musculus)


name: 2,4-dihydroxybenzoate + H(+) <=> CO2 + resorcinol


name: an N-(1,2-saturated acyl)sphinganine + H(+) + NADPH + O2 <=> an N-(2-hydroxyacyl)-sphinganine + H2O + NADP(+)


name: 12,13-epoxy-(9Z,11E,15Z)-octadecatrienoate + H2O => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Sus scrofa)


name: XDH dehydrogenates xanthine to form urate (Homo sapiens)


name: LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Sus scrofa)


name: RNA Polymerase II Promoter Opening: First Transition (Bos taurus)


name: Export of peptide loaded MHC class I complex to PM (Danio rerio)


name: (2E,6E)-farnesyl diphosphate <=> alpha-himachalene + diphosphate


name: IDO2 dioxygenates L-Trp to NFK (Canis familiaris)


name: Phosphorylation of LIMK-1 by PAK (Xenopus tropicalis)


name: a (2R,3R)-dihydroflavonol + H(+) + NADPH => a (2R,3S,4S)-leucoanthocyanidin + NADP(+)


name: Interleukin-12 binds Interleukin-12 receptor (Canis familiaris)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Xenopus tropicalis)


name: Formation of the 19S regulatory particle precursor (Xenopus tropicalis)


name: a long-chain fatty acid(out) => a long-chain fatty acid(in)


name: H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine


name: 1'-hydroxyversicolorone + H(+) + NADPH => (2S)-versicolorone + NADP(+)


name: PI:PITPNB is transported from the ER membrane to the Golgi membrane (Plasmodium falciparum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol <=> 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: chrodrimanin T + H(+) + NADPH + O2 = chrodrimanin A + H2O + NADP(+)


name: HSD11B2 dehydrogenates PREDL to PREDN (Gallus gallus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate


name: 1D-myo-inositol 1,4-bisphosphate + H2O <=> 1D-myo-inositol 4-phosphate + phosphate


name: a ganglioside Ac-O-7-GD1a (d18:1(4E)) <=> a ganglioside Ac-O-8-GD1a (d18:1(4E))


name: Exocytosis of platelet alpha granule contents (Schizosaccharomyces pombe)


name: PTK6 phosphorylates ARHGAP35 (Sus scrofa)


name: H(+) + N(2)-(ADP-D-ribosyl)-dGTP + nicotinamide => dGTP + NAD(+)


name: 4,5-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO2


name: alpha-D-xylose 1-phosphate + H(+) + UTP <=> diphosphate + UDP-alpha-D-xylose


name: diphosphate + neoabietadiene => (+)-copalyl diphosphate


name: SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Homo sapiens)


name: Translocation of activated BAD protein to mitochondria (Mus musculus)


name: SRC-1 phosphorylates PTK2-beta (Homo sapiens)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Schizosaccharomyces pombe)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Homo sapiens)


name: (S,S)-tartrate(in) + sulfate(out) <=> (S,S)-tartrate(out) + sulfate(in)


name: CUBN dissociates from 25(OH)D (Caenorhabditis elegans)


name: Conversion of DHA-CoA to docosahexaenoic acid (DHA) (Mus musculus)


name: carbovir + IMP => carbovir monophosphate + inosine (Drosophila melanogaster)


name: Formation of ERCC1:XPF heterodimeric complex (Plasmodium falciparum)


name: GBF1 recruits ARF:GDP to the ERGIC (Drosophila melanogaster)


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H(+) + NADPH => 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + NADP(+)


name: Protein Kinase B/Akt phosphorylates BRF1 (Saccharomyces cerevisiae)


name: p-T68-CHEK2 autophosphorylates (Saccharomyces cerevisiae)


name: Recruitment of Rad17-RFC complex to DNA (Plasmodium falciparum)


name: H(+) + NADPH + S-formylglutathione => NADP(+) + S-(hydroxymethyl)glutathione


name: an N-acylsphing-4-enine + UDP-alpha-D-glucose = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN2C (GRIN2C) (Homo sapiens)


name: TNIPs bind TNFAIP3 (A20) (Canis familiaris)


name: an acyl-CoA + sn-glycerol 3-phosphocholine = a monoacyl-sn-glycero-3-phosphocholine + CoA


name: (R)-carnitine(out) + O-acetyl-(R)-carnitine(in) = (R)-carnitine(in) + O-acetyl-(R)-carnitine(out)


name: 27-hydroxysterol binds ESR1, ESR2 (Homo sapiens)


name: galactitol 1-phosphate + NAD(+) = H(+) + keto-D-tagatose 6-phosphate + NADH


name: (S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-dichlorophenol + CO2 + pyruvate + succinate


name: H2O + N-acetyl-D-glucosamino-1,5-lactone = H(+) + N-acetyl-D-glucosaminate


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Rattus norvegicus)


name: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O => (7R)-7-aminocephalosporanate + glutarate


name: (2E,6E)-farnesyl diphosphate + H2O => diphosphate + gamma-eudesmol


name: CDC42:GTP recruits DIAPH2-2 to kinetochores (Sus scrofa)


name: PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Caenorhabditis elegans)


name: RHAG transports CO2 from extracellular region to cytosol (Bos taurus)


name: glyoxal + GTP => N(2)-(1-hydroxy-2-oxoethyl)-GTP


name: KIBRA (WWC1) binds LATS proteins (Gallus gallus)


name: GLA hydrolyzes PSAP(195-273):Gb3Cer:PE (Sus scrofa)


name: c-FOS activation by phospho ERK1/2 (Mus musculus)


name: chlorophyllide a + 2 H(+) <=> Mg(2+) + pheophorbide a


name: PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Rattus norvegicus)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Danio rerio)


name: (2E)-octenedioyl-CoA + H2O = (3S)-hydroxyoctanedioyl-CoA


name: Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Rattus norvegicus)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Danio rerio)


name: dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+) => dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2


name: Formation of Malonyl-CoA from Acetyl-CoA (liver) (Rattus norvegicus)


name: N-acetylserotonin + S-adenosyl-L-methionine = H(+) + melatonin + S-adenosyl-L-homocysteine


name: Transport of SEC22B, TAP and PLC from ER to ERGIC (Mus musculus)


name: a flavonol 3-O-beta-D-glucoside + malonyl-CoA <=> a flavonol 3-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Homo sapiens)


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Saccharomyces cerevisiae)


name: FBXL3 binds phosphorylated CRY proteins (Homo sapiens)


name: dimethylallyl diphosphate => diphosphate + isoprene


name: CTP(out) + IMP(in) => CTP(in) + IMP(out)


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Canis familiaris)


name: Mcm2-7 is phosphorylated by DDK (Rattus norvegicus)


name: 2-oxoglutarate + L-aspartyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: chloride(out) + Na(+)(out) + serotonin(out) = chloride(in) + Na(+)(in) + serotonin(in)


name: an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O => an N-acyl-(4R)-4-hydroxysphinganine + H(+) + mannosyldiinositol-1-phosphate


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)


name: IL20 binds to IL22RA1:JAK1:IL20RB (Homo sapiens)


name: 2-oxoglutarate + a 3-methyl fatty acyl-CoA + O2 = a 2-hydroxy-3-methyl fatty acyl-CoA + CO2 + succinate


name: apo-[corrinoid adenosyltransferase] + cob(II)yrinate a,c diamide = cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase]


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Danio rerio)


name: Association of INK4 family proteins with CDK4/6 (Sus scrofa)


name: 2-oxoadipate + L-kynurenine => H2O + kynurenate + L-2-aminoadipate


name: H(+) + malonyl-[ACP] + octadecanoyl-[ACP] = 3-oxoeicosanoyl-[ACP] + CO2 + holo-[ACP]


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Homo sapiens)


name: benzyl alcohol + NAD(+) <=> benzaldehyde + H(+) + NADH


name: snRNP nuclear import and release (Mus musculus)


name: (9Z)-octadecenoyl-CoA + sphinganine = CoA + H(+) + N-(9Z-octadecenoyl)-sphinganine


name: aldehydo-D-glucose 6-phosphate + L-lysyl-[protein] = H2O + N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein]


name: Class IV antihypertensives bind LTCC multimer (Drosophila melanogaster)


name: Orc1 is phosphorylated by cyclin A/CDK2 (Mus musculus)


name: 24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 <=> 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Rattus norvegicus)


name: 4-methylumbelliferone sulfate(in) + ATP + H2O => 4-methylumbelliferone sulfate(out) + ADP + H(+) + phosphate


name: Exocytosis of specific granule lumen proteins (Dictyostelium discoideum)


name: ESTG binds ESR1:chaperone complex (Drosophila melanogaster)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Canis familiaris)


name: RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Gallus gallus)


name: arginine + H2O => ornithine + urea [ARG1] (Dictyostelium discoideum)


name: GAB1 phosphorylation by EGFR kinase (Bos taurus)


name: ATG7:ATG3:LC3 dissociates (Schizosaccharomyces pombe)


name: GLI3R translocates to the nucleus (Bos taurus)


name: ADP + gamma-L-glutamylspermidine + H(+) + phosphate => ATP + L-glutamate + spermidine


name: Formation of the CE:GMP intermediate complex (Drosophila melanogaster)


name: SREBP1A,1C,2:Importin beta-1 dissociates (Caenorhabditis elegans)


name: 5-phosphoribosylglycinamide (GAR) + 10-formyl-tetrahydrofolate => 5'-phosphoribosylformylglycinamide (FGAR) + tetrahydrofolate (Gallus gallus)


name: adenosine(34) in tRNA + H(+) + H2O <=> inosine(34) in tRNA + NH4(+)


name: 2-AG hydrolysis to arachidonate by MAGL (Homo sapiens)


name: F1 binds to F2 forming the F subunit (Homo sapiens)


name: RUNX3 binds TEADs and YAP1 (Gallus gallus)


name: SUMOylation of UBE2I with SUMO1 (Xenopus tropicalis)


name: ATM phosphorylates ZNF420 (Drosophila melanogaster)


name: SERPINB13 binds cathepsin L (Bos taurus)


name: (+)-minovincinine + acetyl-CoA <=> (+)-echitovenine + CoA


name: ATP + coproporphyrinogen III(in) + H2O => ADP + coproporphyrinogen III(out) + H(+) + phosphate


name: (8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine => (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate


name: carbovir + IMP => carbovir monophosphate + inosine (Homo sapiens)


name: Furin cleaves pro-protein S to protein S (Xenopus tropicalis)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Bos taurus)


name: IRE1 dimer autophosphorylates (Gallus gallus)


name: 4beta-hydroxycholesterol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-4beta,26-dihydroxycholesterol + H2O + 2 oxidized [adrenodoxin]


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Sus scrofa)


name: H2O + N-formimidoyl-L-aspartate = N-formyl-L-aspartate + NH4(+)


name: RAD51B:RAD51C binds single-stranded DNA (Mus musculus)


name: CBL monoubiquitinates activated MET (Rattus norvegicus)


name: L-arginine + O2 + reduced [flavodoxin] => H(+) + H2O + N(omega)-hydroxy-L-arginine + oxidized [flavodoxin]


name: ME1 tetramerizes (Caenorhabditis elegans)


name: CYP1A2 S-demethylates 6MMP (Rattus norvegicus)


name: RAB6:GTP and BICD homodimers bind COPI-independent Golgi-to-ER retrograde cargo (Gallus gallus)


name: (2S)-naringenin + UDP-alpha-D-glucose = (2S)-naringenin 7-O-beta-D-glucoside + H(+) + UDP


name: H2O + N-acetyl-beta-alanine = acetate + beta-alanine


name: RHOQ binds effectors at the plasma membrane (Gallus gallus)


name: a 3-oxoacyl-CoA + H(+) + NADH => a (3R)-3-hydroxyacyl-CoA + NAD(+)


name: FOXP3 in complex with RUNX1 binds the CTLA4 gene promoter (Homo sapiens)


name: BTG2 binds CCR4-NOT complex (Mus musculus)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Bos taurus)


name: L-alanine + L-histidine => H2O + L-alanyl-L-histidine


name: EPS15 and HGS bind ubiquitinated MET (Canis familiaris)


name: STING recruits TBK1 and STAT6 (Rattus norvegicus)


name: Interaction of Tie2 and p85 of PI3K (Xenopus tropicalis)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H(+) + sulfate => H2O + N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine


name: cAMP hydrolysis by Cam-PDE 1 (Sus scrofa)


name: USP17L2 deubiquitinates RCE1 (Mus musculus)


name: PTGS2 dimer oxidises EPA to PGH3 (Rattus norvegicus)


name: glyceollin II + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase]


name: UCP1 gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD (Homo sapiens)


name: H(+) + hydrogen sulfide + O-phospho-L-seryl-tRNA(Cys) = L-cysteinyl-tRNA(Cys) + phosphate


name: deoxycholate + NAD(+) = 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Drosophila melanogaster)


name: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone + H(+) <=> a quinol + beta-nicotinamide D-riboside


name: (7S)-O-acetylsalutaridinol => acetate + H(+) + thebaine


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Dictyostelium discoideum)


name: N(pros)-phospho-L-histidyl-[protein] + N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine(out) => 6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine(in) + L-histidyl-[protein]


name: [protein]-C-terminal Gly-Gly + ATP + H(+) = [protein]-C-terminal Gly-Gly-AMP + diphosphate


name: CYP26C1 4-hydroxylates 9cRA (Homo sapiens)


name: histone H4K16 propionyltransferase activity


name: Formation of the SET1B complex (Homo sapiens)


name: Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Drosophila melanogaster)


name: 1,3-di-(9Z)-octadecenoyl-2-hexadecanoylglycerol + H2O = 1,3-di-(9Z-octadecenoyl)-glycerol + H(+) + hexadecanoate


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(out) + ADP + H(+) + phosphate


name: 2'''-acetyl-6'''-hydroxyneomycin C + H2O = 6'''-deamino-6'''-hydroxyneomycin C + acetate


name: 4-methylsulfanyl-2-oxobutanoate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-methionine


name: mTORC1 phosphorylates AKT1S1 (Homo sapiens)


name: Receptor FFAR2 binds carboxylates (Canis familiaris)


name: G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC (Homo sapiens)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Homo sapiens)


name: H(+)(out) + L-leucine(in) => H(+)(in) + L-leucine(out)


name: IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Canis familiaris)


name: doxorubicin(in) + H(+)(out) => doxorubicin(out) + H(+)(in)


name: glutathione-regulated potassium exporter activity


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Homo sapiens)


name: a fatty acyl-CoA + hexadecasphinganine => CoA + H(+) + N-acylhexadecasphinganine


name: L-arginine + O2 + reduced [flavodoxin] = H(+) + H2O + N(omega)-hydroxy-L-arginine + oxidized [flavodoxin]


name: PAK1 autophosphorylates (Xenopus tropicalis)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-(O-farnesylgeranyl)glycerol 1-phosphate


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Sus scrofa)


name: an N-acylsphing-4-enine + CoA + H(+) => a fatty acyl-CoA + sphing-4-enine


name: Phospho-JAK2 phosphorylates EPOR (Homo sapiens)


name: Phosphorylated RHOU translocates to the endosome membrane (Gallus gallus)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O => (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: 2 H(+) + isoproturon + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 1-methyl-3-[4-(propan-2-yl)phenyl]urea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PAO:FAD oxidises NASPM to PTCN (Bos taurus)


name: DDX41 ubiquitination by TRIM21 (Mus musculus)


name: FadD26, FadD28 transfer adenylyl group to a LCFA (Mycobacterium tuberculosis)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [one-chain] catalyst) (Sus scrofa)


name: 3alpha-hydroxy-5alpha-pregnan-20-one + NAD(+) = 5alpha-pregnane-3,20-dione + H(+) + NADH


name: [(3R)-hydroxybutanoate](n+1) + CoA => (3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Bos taurus)


name: gamma-L-glutamyl-hercynylcysteine S-oxide + H2O => L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide


name: a ganglioside GD2 + UDP-alpha-D-galactose <=> a ganglioside GD1b + H(+) + UDP


name: NT5C2 tetramer phosphorylates RBV (Xenopus tropicalis)


name: ROK phosphorylates MBS (Drosophila melanogaster)


name: Prolysyl oxidase activation (Danio rerio)


name: Importin-8 binds AGO2:miRNA (Mus musculus)


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Mus musculus)


name: creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate = calarene + diphosphate


name: NOTCH3-ligand complex is cleaved to produce NEXT3 (Rattus norvegicus)


name: coenzyme B + coenzyme M + methanophenazine <=> coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine


name: CDP-DAG is converted to PI by CDIPT (Dictyostelium discoideum)


name: PGH2 is isomerised to PGD2 by PTGDS (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = a 2-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: a dicarboxylate(in) + urate(out) = a dicarboxylate(out) + urate(in)


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Xenopus tropicalis)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Homo sapiens)


name: 5-C(alpha)-glycyl-dTMP in DNA + H(+) <=> 5-aminoethyl-dUMP in DNA + CO2


name: CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Canis familiaris)


name: archaeosine(15) in tRNA + L-glutamate => 7-cyano-7-carbaguanosine(15) in tRNA + H2O + L-glutamine


name: beta-D-fructose 6-phosphate + GDP-alpha-D-mannose = beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + GDP + H(+)


name: [DsrC protein]-S-sulfo-L-cysteine/L-cysteine <=> [DsrC protein]-disulfide + H(+) + sulfite


name: alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O = alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate + H(+)


name: "alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase"


name: a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: an N-acyl-sphingoid base + CDP-ethanolamine = an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H(+)


name: n H(+)(in) + serotonin(out) => n H(+)(out) + serotonin(in)


name: (S)-malate(in) + glycolate(out) => (S)-malate(out) + glycolate(in)


name: (R)-dihydrocamalexate + O2 + reduced [NADPH--hemoprotein reductase] => camalexin + CO2 + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: glycyl-L-glutamate + H2O => glycine + L-glutamate


name: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+) => 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane


name: D-fructose + phosphate => beta-D-fructose 1-phosphate + H2O


name: (E)-cinnamate + S-adenosyl-L-methionine = (E)-cinnamic acid methyl ester + S-adenosyl-L-homocysteine


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Bos taurus)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] (Xenopus tropicalis)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Homo sapiens)


name: TRPV1 binds TRPV1 blockers (Mus musculus)


name: 5beta-cholestan-3-one + NADP(+) => cholest-4-en-3-one + H(+) + NADPH


name: FFAR1 binds rosiglitazone (Canis familiaris)


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Homo sapiens)


name: PTPN3 dephosphorylates MAPK12 (Gallus gallus)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Dictyostelium discoideum)


name: ATP(in) + CoA(in) + decanoate(out) + H(+)(out) => AMP(in) + decanoyl-CoA(in) + diphosphate(in) + H(+)(in)


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Schizosaccharomyces pombe)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacylglycerol => a 1-acyl-sn-glycero-3-phosphocholine + a triacylglycerol


name: RAS:GTP binds RAL GDS proteins (Homo sapiens)


name: guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine => H(+) + N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine


name: (13S,14R)-13-O-acetyl-1-hydroxy-N-methylcanadine + CoA => (13S,14R)-1,13-dihydroxy-N-methylcanadine + acetyl-CoA


name: prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer (Sus scrofa)


name: CCL17 and CCL22 genes are transcribed (Homo sapiens)


name: RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Caenorhabditis elegans)


name: Dephosphorylation of TYK2 by PTP1B (Canis familiaris)


name: Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol (Homo sapiens)


name: Salvage - Sepiapterin is reduced to q-BH2 (Dictyostelium discoideum)


name: Activated FGFR4:p-FRS bind to PPTN11 (Rattus norvegicus)


name: copal-8-ol diphosphate synthase activity


name: 3'-phosphoadenylyl sulfate + an alcohol <=> adenosine 3',5'-bisphosphate + an alkyl sulfate + H(+)


name: H(+) + L-serine + sn-glycerol 3-phosphate => H2O + sn-glycero-3-phospho-L-serine


name: Formation of the 43S pre-initiation complex (Gallus gallus)


name: 1-eicosanoylglycerol + H2O <=> eicosanoate + glycerol + H(+)


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Drosophila melanogaster)


name: S-adenosyl-L-methionine + uridine(32) in tRNA = 2'-O-methyluridine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: TIGAR converts D-fructose-2,6-bisphosphate to D-fructose 6-phosphate (Mus musculus)


name: (S)-1-pyrroline-5-carboxylate + 2 H2O + NAD(+) = H(+) + L-glutamate + NADH


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(out) = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(in)


name: ATG12 forms a thioester bond with ATG7 dimer (Rattus norvegicus)


name: (1S)-3-methyl-cyclohexylamine + H2O + NADP(+) => 3-methylcyclohexanone + H(+) + NADPH + NH4(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine => 2-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: Association of procollagen type XXIV (Sus scrofa)


name: ATP + propanoate => ADP + propanoyl phosphate


name: (9Z,12Z)-octadecadienoyl-CoA + H2O <=> (9Z,12Z)-octadecadienoate + CoA + H(+)


name: 3-phenylpyruvate + carboxy-S-adenosyl-L-methionine + H2O => prephenate + S-adenosyl-L-methionine


name: (+)-isomalbrancheamide D + FADH2 => (+)-isomalbrancheamide B + bromide + FAD + 2 H(+)


name: D-xylose transmembrane transporter activity


name: TRADD:TRAF2:RIP1 complex binds FADD (Gallus gallus)


name: ALOX12 oxidises LTA4 to LXB4 (Dictyostelium discoideum)


name: Keratin filaments bind cell-cell adhesion complexes (Xenopus tropicalis)


name: Isomerization of 25(R) TetraHCA-CoA to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Caenorhabditis elegans)


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Sus scrofa)


name: 2-phenylethanol + NAD(+) => 2-phenylacetaldehyde + H(+) + NADH


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-tetradecanoyl-sn-glycero-3-phosphocholine = 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADH => H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+)


name: Galpha-olf:GTP binds to adenylate cyclase and activates it (Dictyostelium discoideum)


name: (2E,6E)-farnesyl diphosphate + H2O = alpha-eudesmol + diphosphate


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Mus musculus)


name: 6alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => estrone + O2 + reduced [NADPH--hemoprotein reductase]


name: LONP1 binds mitochondrial inner membrane proteins (Dictyostelium discoideum)


name: 4-methyl-2-oxopentanoate(out) + 2 Na(+)(out) <=> 4-methyl-2-oxopentanoate(in) + 2 Na(+)(in)


name: Caspase-mediated cleavage of Desmoplakin (Danio rerio)


name: an S-substituted glutathione + H2O => glycine + S-substituted gamma-glutamyl-L-cysteine


name: (S)-canadine + H(+) + 2 O2 <=> berberine + 2 H2O2


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Danio rerio)


name: MITF-M dimer binds the LIG1 gene (Homo sapiens)


name: GDIs block activation of RHOG (Xenopus tropicalis)


name: ATP + CoA + eicosanoate <=> AMP + diphosphate + eicosanoyl-CoA


name: H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + pseudobaptigenin => calycosin + O2 + reduced [NADPH--hemoprotein reductase]


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Canis familiaris)


name: NGEF exchanges GTP for GDP on RHOA (Drosophila melanogaster)


name: RNA polymerase III type 3 promoter sequence-specific DNA binding


name: D-arabinono-1,4-lactone + H2O <=> D-arabinonate + H(+)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Sus scrofa)


name: (S)-dihydroorotate + a menaquinone = a menaquinol + orotate


name: LRP1 (CD91) binds Hemopexin:heme (Rattus norvegicus)


name: a 1,2-diacylglycerol + a 1-acylglycerol = a triacylglycerol + glycerol


name: H2O + N-(6-aminohexanoyl)-6-aminohexanoate = 2 6-aminohexanoate


name: 3-oxododecanedioyl-CoA + CoA = acetyl-CoA + decanedioyl-CoA


name: LMAN family proteins bind glycosylated cargo (Bos taurus)


name: 1,2-dioctanoyl-sn-glycerol + CDP-choline = 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: 6-linalyl-2-O,3-dimethylflaviolin + diphosphate => (2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin


name: Crk's SH3 domain engages C3G (Sus scrofa)


name: Substrate:LAMP2a:HSP90 polymerizes (Homo sapiens)


name: (2E)-tetradecenoyl-CoA + H(+) + NADPH = NADP(+) + tetradecanoyl-CoA


name: ATP + streptomycin <=> ADP + H(+) + streptomycin 3''-phosphate


name: (2S)-naringenin 4'-methyl ether + H(+) + S-adenosyl-L-homocysteine => (2S)-naringenin + S-adenosyl-L-methionine


name: BIL dissociates from GSTA1, FABP1 (Rattus norvegicus)


name: COMT transfers Met to DOPAC to form HVA (Rattus norvegicus)


name: LMF1,2 transport LIPC dimer from ER lumen to extracellular region (Bos taurus)


name: CysS248-MPST:TXN2 dissociates (Homo sapiens)


name: CS acetylates OA to citrate (Canis familiaris)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Sus scrofa)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Mus musculus)


name: H(+) + 2 L-methionine => L-homocysteine + S-methyl-L-methionine


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose => a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: COX18 inserts nascent MT-CO2 in COX20:TMEM77 (Bos taurus)


name: BTG1 gene expression is stimulated by FOXO3 (Homo sapiens)


name: Inhibin-A binding to TGFBR3 (Canis familiaris)


name: Exchange of oxygen with sulfur in MoCo (Rattus norvegicus)


name: 3-(methylsulfanyl)propanoate + ATP + CoA => 3-(methylsulfanyl)propanoyl-CoA + AMP + diphosphate


name: Necl-2:Nectin 3 trans heterodimer interaction (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ethanolamine => H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: urokinase plasminogen activator (two-chain):uPAR + plasminogen activator inhibitor 1 (PAI-1) -> PAI-1:urokinase plasminogen activator (two-chain):uPAR (Homo sapiens)


name: NNMT transfers CH3 from AdoMet to PY (Canis familiaris)


name: RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Canis familiaris)


name: GLRA:GLRB:Gly transports extracellular Cl- to cytosol (Caenorhabditis elegans)


name: Anthrax lef cleaves target cell MAP2K1 (MEK1) (Homo sapiens)


name: 2 AMP + asperphenamate + 2 diphosphate + H(+) => 2 ATP + benzoate + L-phenylalanine + N-benzoyl-L-phenylalaninol


name: androsterone dehydrogenase (B-specific) activity


name: 1,3-dinitrobenzene + NADH + O2 => 4-nitrocatechol + H(+) + NAD(+) + nitrite


name: ATP + streptomycin => ADP + H(+) + streptomycin 3''-phosphate


name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin (Canis familiaris)


name: H2O + N-(9Z-octadecenoyl)-L-isoleucine = (9Z)-octadecenoate + L-isoleucine


name: Inner coat assembly and cargo binding (Rattus norvegicus)


name: Unphosphorylated nucleoprotein translocates to the plasma membrane (Homo sapiens)


name: PIP3 recruits PDPK1 to the membrane (Homo sapiens)


name: 3 a quinone + protoporphyrinogen IX => 3 a quinol + protoporphyrin IX


name: 1-acyl LPI is acylated to PI by MBOAT7 (Saccharomyces cerevisiae)


name: Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 (Sus scrofa)


name: KCNK dimers transport K+ from cytosol to extracellular region (Danio rerio)


name: ATP + glycine betaine(out) + H2O => ADP + glycine betaine(in) + H(+) + phosphate


name: a di-trans,poly-cis-dolichyl phosphate + D-glucose + H(+) => a di-trans,poly-cis-dolichyl beta-D-glucosyl phosphate + H2O


name: 3 AH2 + 2 H(+) + heme b + 3 O2 <=> 3 A + Fe(2+) + 3 H2O + mycobilin b


name: p-T182 MAPKAPK5 phosphorylates FOXO3 (Rattus norvegicus)


name: chlorobenzene + H(+) + NADH + O2 => (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+)


name: ADP + D-glucose(in) + H(+) + phosphate => ATP + D-glucose(out) + H2O


name: 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate => 7,8-dihydroneopterin 3'-phosphate + H2O


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: NR1H2,3 binds the APOC2 gene (Homo sapiens)


name: N-acetyl-D-glucosamine 6-phosphate => N-acetyl-alpha-D-glucosamine 1-phosphate


name: Translocation of NFATC1:CaN:CaM to nucleus (Bos taurus)


name: (E)-caffeoyl-CoA + H2O = 3,4-dihydroxybenzaldehyde + acetyl-CoA


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Gallus gallus)


name: daturadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase]


name: IL21 binds IL21R:JAK1 (Rattus norvegicus)


name: Recognition and Binding of Core Promoter Elements by TFIID (Gallus gallus)


name: H(+) + N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => L-lysyl-[protein] + S-adenosyl-L-methionine


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Mus musculus)


name: mating-type M-factor pheromone receptor activity


name: RHOV binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Caenorhabditis elegans)


name: gibberellin A20 + S-adenosyl-L-methionine => gibberellin A20 methyl ester + S-adenosyl-L-homocysteine


name: Oxidative demethylation of 3-meC damaged DNA By ALKBH3 (Homo sapiens)


name: 4-aminobutanal + L-alanine => putrescine + pyruvate


name: Fibrillin-1 degradation by MMP14 (Gallus gallus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Drosophila melanogaster)


name: [phosphate](n) + a di-trans,poly-cis-dolichyl diphosphate = [phosphate](n+1) + a di-trans,poly-cis-dolichyl phosphate


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity


name: CDP-DAG is converted to PI by CDIPT (Homo sapiens)


name: Cleavage of adenine mispaired with 8-oxoguanine by MUTYH (Bos taurus)


name: NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Bos taurus)


name: SUMOylation of Histone H4 with SUMO1 (Danio rerio)


name: 3-oxohexadecasphinganine + CO2 + CoA => H(+) + L-serine + tetradecanoyl-CoA


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Bos taurus)


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Homo sapiens)


name: Trimming of peptides by IRAP in endocytic vesicles (Mus musculus)


name: (R)-dihydrolipoate + ATP + L-lysyl-[lipoyl-carrier protein] = AMP + diphosphate + H(+) + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein]


name: 2-furoyl-CoA + A + H2O = 5-hydroxy-2-furoyl-CoA + AH2 + H(+)


name: Resolution of sister chromatids (Canis familiaris)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O <=> (9Z)-octadecenoate + H(+) + sn-glycero-3-phospho-(1'-sn-glycerol)


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate


name: 2-phenylethylamine + H2O + O2 <=> 2-phenylacetaldehyde + H2O2 + NH4(+)


name: (3R)-hydroxy-4-methylpentanoyl-[ACP] + NADP(+) => 4-methyl-3-oxopentanoyl-[ACP] + H(+) + NADPH


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Sus scrofa)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Dictyostelium discoideum)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Schizosaccharomyces pombe)


name: CYP3A43 6b-hydroxylates TEST (Mus musculus)


name: acetyl-CoA + chloramphenicol = chloramphenicol 3-acetate + CoA


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Saccharomyces cerevisiae)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (20S)-ginsenoside Rg1 + H2O = (20S)-ginsenoside F1 + D-glucose


name: Dissociation of the COP1-p53 complex (Mus musculus)


name: ISGylation of protein translation regulator 4EHP (Bos taurus)


name: Formation of the inner ring of the 20S core particle of the 26S proteasome (Rattus norvegicus)


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Rattus norvegicus)


name: H2O + O2 + retinal = H(+) + H2O2 + retinoate


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Bos taurus)


name: Recognition of the Nuclear Localization Signal (NLS) by a Karyopherin Alpha Family Protein (Homo sapiens)


name: BDH2 dehydrogenates 3HBA (Rattus norvegicus)


name: PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Mus musculus)


name: Release of E3 from polyubiquitinated substrate (Canis familiaris)


name: (2E)-octenoyl-[ACP] + H(+) + NADPH <=> NADP(+) + octanoyl-[ACP]


name: NUDT15 dimer dephosphorylates 6TdGTP to 6TdGMP (Bos taurus)


name: a ganglioside GT1b + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1b + CMP + H(+)


name: dioctanoylglycerol + H(+) + octanoate => 1,2,3-trioctanoylglycerol + H2O


name: H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate => acetylsalicylate + L-lysyl-[protein]


name: DLST transfers succinyl to CoA (Plasmodium falciparum)


name: ALOX5 binds ALOX5 inhibitors (Xenopus tropicalis)


name: 4-nitrobenzoate + 2 H(+) + 2 NADH => 4-hydroxylaminobenzoate + H2O + 2 NAD(+)


name: acetyl-CoA + spermine <=> CoA + H(+) + N(1)-acetylspermine


name: TRMT10A methylates guanosine-9 in tRNA (Homo sapiens)


name: Necl-1:Nectin 3 trans heterodimer interaction (Sus scrofa)


name: 2-oxoglutarate + L-prolyl-[Skp1 protein] + O2 => CO2 + succinate + trans-4-hydroxy-L-prolyl-[Skp1 protein]


name: H2O + substance P <=> L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-7)


name: CoA + taxuyunnanin C => 10-deacetyltaxuyunnanin C + acetyl-CoA


name: SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases (Canis familiaris)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: (14R,15R)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate => (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O


name: MIA2 and MIA3 load procollagen VII into COPII vesicles (Homo sapiens)


name: Binding of Grb10 to the insulin receptor (Gallus gallus)


name: N(6),N(6)-dimethyl-L-lysyl-[histone] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine


name: PA is dephosphorylated to DAG by LPIN (Caenorhabditis elegans)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Danio rerio)


name: 2-oxoglutarate + L-arogenate => L-glutamate + prephenate


name: 2,3-dihydroxy-p-cumate + H(+) + NADH => (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+)


name: Receptor ACKR2 binds most inflammatory CC chemokines (Gallus gallus)


name: acetyl-CoA + decanoyl-CoA => 3-oxododecanoyl-CoA + CoA


name: 3-methylcatechol + O2 <=> 2-hydroxy-6-oxo-2,4-heptadienoate + H(+)


name: Formation of the IGF:IGFBP5:ALS complex (Rattus norvegicus)


name: N(2)-(1-hydroxy-2-oxoethyl)-GMP => glyoxal + GMP


name: Caspase-mediated cleavage of Z0-2 (Canis familiaris)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Sus scrofa)


name: a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base => a 1,3-diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base


name: EXT1:EXT2 transfer GlcNAc to the heparan chain (Drosophila melanogaster)


name: NTHL1 D239Y does not cleave dihydrouracil (DHU) (Homo sapiens)


name: a ganglioside GM3 + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GD3 + CMP + H(+)


name: UBA6 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)


name: D-malate dehydrogenase (decarboxylating) (NAD+) activity


name: ADP + H(+) + N-acetyl-alpha-D-muramate 1-phosphate => ATP + N-acetyl-D-muramate


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: 1-deoxypentalenate + 2 H(+) + O2 + reduced 2[4Fe-4S]-[ferredoxin] = H2O + oxidized 2[4Fe-4S]-[ferredoxin] + pentalenate


name: PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Xenopus tropicalis)


name: LIG3 ligates remaining SSBs in MMEJ (Canis familiaris)


name: UDP-alpha-D-glucose + vanillate <=> 1-O-(4-hydroxy-3-methoxybenzoyl)-beta-D-glucose + UDP


name: AMP + dimethylallyl diphosphate = diphosphate + N(6)-(dimethylallyl)adenosine 5'-phosphate


name: STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Rattus norvegicus)


name: Dissociation of p-Y427-SHC1 from insulin receptor (Homo sapiens)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: 17beta-hydroxyestr-4-en-3-one + H(+) + NADPH = 17beta-hydroxy-5beta-estran-3-one + NADP(+)


name: phycocyanobilin-L-cysteinyl(84)-[allophycocyanin beta-subunit] <=> (2R,3E)-phycocyanobilin + apo-L-cysteinyl(84)-[allophycocyanin beta-subunit]


name: 4-hydroxy-L-proline(out) + chloride(out) + 2 Na(+)(out) => 4-hydroxy-L-proline + chloride(in) + 2 Na(+)(in)


name: [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase activity


name: 2',3'-cyclophospho-AMP + RNA(n) => RNA(n)-3'-adenine ribonucleotide


name: phycoerythrobilin-L-cysteinyl(84)-[C-phycoerythrin beta-subunit] = (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[C-phycoerythrin beta-subunit]


name: 2-(glutathion-S-yl)-2-(1H-indol-3-yl)acetonitrile + H2O = 2-(glycyl-L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + L-glutamate


name: ATP + glutathione(in) + glycocholate(in) + H2O = ADP + glutathione(out) + glycocholate(out) + H(+) + phosphate


name: RAC2 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: H2O + TTP <=> 5-methyl-UMP + diphosphate + H(+)


name: Formation of dehydro-lysinonorleucine cross-links (Canis familiaris)


name: 1,4-dihydroxy-2-naphthoate + all-trans-decaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-10 + CO2 + diphosphate


name: a plastoquinone + (n+1) H(+)(in) + NADH = a plastoquinol + n H(+)(out) + NAD(+)


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Rattus norvegicus)


name: dihydromonacolin L carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = 3alpha-hydroxy-3,5-dihydromonacolin L carboxylate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: galactarate <=> (2S,3R)-dihydroxy-5-oxohexanedioate + H2O


name: 2 chloride(out) + glycine betaine(out) + 3 Na(+)(out) => 2 chloride(in) + glycine betaine(in) + 3 Na(+)(in)


name: USP19 binds HIF1A,BIRC2,BIRC3 (Homo sapiens)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Drosophila melanogaster)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Sus scrofa)


name: 2-oxindole-3-acetate + succinyl-CoA <=> (2-oxoindol-3-yl)acetyl-CoA + succinate


name: ANPEP:Zn2+ hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8) (Homo sapiens)


name: Formation of Cyclin A:Cdk2 complexes (Gallus gallus)


name: AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Bos taurus)


name: (11Z)-3-oxoicosenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(11Z)-eicosenoyl-CoA + NADP(+)


name: histone H3K18 acetyltransferase activity


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: 4beta-hydroxymethyl-4alpha-methylzymosterol + H(+) + NADH + O2 <=> 4beta-formylmethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 H2O + NAD(+)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Sus scrofa)


name: Pannexin 1/Pannexin2 mediated neuronal gap junction communication (Gallus gallus)


name: (2E)-tetradecenoyl-CoA + H2O => (3S)-hydroxytetradecanoyl-CoA


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) + N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein] <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-histidyl-[protein]


name: TRAF6/or TRAF2 interacts with IPS-1 (Gallus gallus)


name: Progesterone stimulation promotes PGR:P4 binding to ESR1:ESTG (Homo sapiens)


name: ALDH1A1 oxidises GA to DGA (Drosophila melanogaster)


name: (R)-adrenaline + H2O + O2 <=> (R)-3,4-dihydroxymandelaldehyde + H2O2 + methylamine


name: (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + NADP(+) => 3-oxo-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA + H(+) + NADPH


name: (E)-feruloyl-CoA + myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] => CoA + H(+) + myricetin 3-O-[(6-O-[(E)-feruloyl]-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside]


name: Proteasome degrades ubiquitinated ROBO3.1 (Homo sapiens)


name: NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)


name: guanine(out) + Na(+)(out) => guanine(in) + Na(+)(in)


name: VTN binds collagens II, III and V (Sus scrofa)


name: L-arginine(out) + L-ornithine(in) <=> L-arginine(in) + L-ornithine(out)


name: H2O + N(4)-[6-(N-acetyl-alpha-D-glucosaminyl-1-phospho)-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein] <=> H(+) + N(4)-[6-phospho-alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(glycan)]-L-asparaginyl-[protein] + N-acetyl-D-glucosamine


name: B4GALNT1 dimer transfers GalNAc to gangliosides (Homo sapiens)


name: (2E)-octenedioyl-CoA + H2O2 => O2 + octanedioyl-CoA


name: methyl benzoate + S-adenosyl-L-homocysteine => benzoate + S-adenosyl-L-methionine


name: SUMOylation of TOP1 with SUMO1 (Dictyostelium discoideum)


name: EPH:EFN tetramers oligomerise (Caenorhabditis elegans)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Xenopus tropicalis)


name: L-alanine(out) + L-glutamine(in) + Na(+)(out) = L-alanine(in) + L-glutamine(out) + Na(+)(in)


name: p-PKR dimer phosphorylates PTPN2 (Homo sapiens)


name: Cleavage of Procaspase‑9 to caspase‑9 (Rattus norvegicus)


name: GGT hydrolyses PCTR1 to PCTR2 (Homo sapiens)


name: TRPV1 binds TRPV1 blockers (Homo sapiens)


name: p-T182 MAPKAPK5 phosphorylates FOXO3 (Mus musculus)


name: (3R)-hydroxytetracosanoyl-CoA + NAD(+) <=> 3-oxotetracosanoyl-CoA + H(+) + NADH


name: 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n) => H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline


name: TNF-α:TNFR1 binds NSMAF (Canis familiaris)


name: docosanoyl-CoA + H2O => CoA + docosanoate + H(+)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Rattus norvegicus)


name: cGMP dissociates from CNG channels (Canis familiaris)


name: XDH oxidizes xanthine to form urate (Mus musculus)


name: GLA hydrolyzes PSAP(195-273):Gal2Cer:PE (Dictyostelium discoideum)


name: trans-4-hydroxy-L-proline => (S)-1-pyrroline-5-carboxylate + H(+) + H2O


name: 2-oxoglutarate + L-arginine + O2 = CO2 + guanidine + L-glutamate 5-semialdehyde + succinate


name: an N-(acyl)-sphingosylphosphoethanolamine => an N-(acyl)-sphingosyl-1,3-cyclic phosphate + ethanolamine


name: Exocytosis of ficolin-rich granule lumen proteins (Bos taurus)


name: dUMP + H2O <=> 2'-deoxyuridine + phosphate


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Mus musculus)


name: TPX2 promotes AURKA autophosphorylation (Canis familiaris)


name: T2Rs bind bitter-tasting compounds (Rattus norvegicus)


name: PEX19 binds class I peroxisomal membrane proteins (Gallus gallus)


name: 5alpha-cholesta-7,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 7-dehydrodesmosterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a 1-acylglycerone 3-phosphate + a long chain fatty alcohol <=> 1-O-alkylglycerone 3-phosphate + a long-chain fatty acid + H(+)


name: 2 H(+)(out) + L-alanyl-L-aspartate(out) = 2 H(+)(in) + L-alanyl-L-aspartate(in)


name: Collagen type I binds integrin alpha11beta1 (Mus musculus)


name: (2S)-2-acetolactate + thiamine diphosphate <=> 2-(1-hydroxyethyl)thiamine diphosphate + pyruvate


name: eIF5B:GTP is hydrolyzed and released (Saccharomyces cerevisiae)


name: ATG12 forms a thioester bond with ATG7 dimer (Drosophila melanogaster)


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Mus musculus)


name: D-arabinono-1,4-lactone + H2O = D-arabinonate + H(+)


name: 2-carboxy-5-formylfuran + H2O = 2-carboxy-5-(dihydroxymethyl)furan


name: 3,4-dihydroxybenzoate + H(+) = catechol + CO2


name: NTP Binds Active Site of RNA Polymerase II (Caenorhabditis elegans)


name: H2O + N-(11Z-eicosenoyl)-sphinganine <=> (11Z)-eicosenoate + sphinganine


name: dioscin + 3 H2O = D-glucose + diosgenin + 2 L-rhamnopyranose


name: 3-hydroxy-L-kynurenine + glyoxylate <=> glycine + H2O + xanthurenate


name: D-alanyl-D-alanine + H2O <=> 2 D-alanine


name: AGRN binds Integrins alphaVbeta1 (Other beta1-containing integrins) (Homo sapiens)


name: AGT(34-41) binds to AGTR2 (Gallus gallus)


name: PIAS1,3 SUMOylate MBD1 with SUMO1 (Sus scrofa)


name: TDH tetramer oxidises L-Thr to 2A-3OB (Homo sapiens)


name: an N(7)-methylguanosine in miRNA + S-adenosyl-L-homocysteine => a guanosine in miRNA + S-adenosyl-L-methionine


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Canis familiaris)


name: FNTA:FNTB transfers FARN to GNGT1 (Danio rerio)


name: a quinone + H2O + L-methionyl-[protein] => a quinol + L-methionyl-(S)-S-oxide-[protein]


name: an acyl-CoA + GDP + phosphate => a carboxylate + CoA + GTP


name: ethyl octadecanoate + H2O => ethanol + H(+) + octadecanoate


name: a 2,3-diacyl-sn-glycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)


name: CoA + H(+) + N-acetyl-D-tryptophan => acetyl-CoA + D-tryptophan


name: 3,3',5'-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3,3',5'-triiodo-L-thyronine


name: a ribonucleotidyl-ribonucleotide-RNA + H2O = a 3'-end ribonucleotide-RNA + a 5'-end 5'-phospho-ribonucleoside-RNA + H(+)


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA <=> (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H2O


name: D-arginine + H2O + O2 = 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]


name: all-trans-lycopaoctaene + 2 diphosphate + NAD(+) => 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADH


name: 2 S-adenosyl-L-methionine + sarcosine <=> glycine betaine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: PRICKLE1 is degraded by the proteasome (Canis familiaris)


name: IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Gallus gallus)


name: 7,8-dihydrofolate + ADP + H(+) + phosphate => 7,8-dihydropteroate + ATP + L-glutamate


name: MAPK12 phosphorylates PTPN3 (Sus scrofa)


name: PON1,3 hydrolyse ATVL to ATV (Bos taurus)


name: H2O + N-octadecanoylsphing-4-enine = octadecanoate + sphing-4-enine


name: ERBB4s80 binds YAP1 (Xenopus tropicalis)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Dictyostelium discoideum)


name: (3R)-3-hydroxy-4-oxobutanoate + H2O + NADP(+) + trimethylamine => (R)-carnitine + H(+) + NADPH + O2


name: 1-(9Z-octadecenoyl)-sn-glycerol + phosphate => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: mycinamicin III + S-adenosyl-L-methionine <=> H(+) + mycinamicin IV + S-adenosyl-L-homocysteine


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O <=> 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)


name: MVB Vesicle Formation (Saccharomyces cerevisiae)


name: glutamate uptake by astrocytes (Gallus gallus)


name: malate dehydrogenase (decarboxylating) (NAD+) activity


name: SUMOylation of TOPORS with SUMO1 (Rattus norvegicus)


name: CUL5 mediates ubiquitination of ERBB2 (Sus scrofa)


name: an aldehyde + 2 H(+) + 2 reduced [azurin] => a primary alcohol + 2 oxidized [azurin]


name: EOMES and TBXT (T, Brachyury) bind the SNAI1 gene (Homo sapiens)


name: androst-4-ene-3,17-dione + H(+) + NADPH + O2 <=> H2O + NADP(+) + testololactone


name: AVPR1A,B bind desmopressin (Danio rerio)


name: PP6-PPP6R3 dephosphorylates TERF2 (Mus musculus)


name: CO2 + diphosphate + thiamine phosphate => 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+)


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Bos taurus)


name: Activated CIT binds KIF14 and PRC1 (Rattus norvegicus)


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Mus musculus)


name: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-glucosamine => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: Protein kinase A (PKA) and RPS6KA5 (MSK1) phosphorylates p65 (RELA) subunit (Gallus gallus)


name: (R)-2-hydroxyglutaryl-CoA => (2E)-glutaconyl-CoA + H2O


name: CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Bos taurus)


name: ZIP6 and ZIP14 mediate zinc influx into cells (Mus musculus)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Sus scrofa)


name: norcoclaurine + S-adenosyl-L-methionine => coclaurine + H(+) + S-adenosyl-L-homocysteine


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Dictyostelium discoideum)


name: SLC22A1 transports Cipro into renal cell (Gallus gallus)


name: PNPLA6 hydrolyzes LysoPtdCho (Caenorhabditis elegans)


name: ethyl (R)-3-hydroxyhexanoate + NADP(+) => ethyl 3-oxohexanoate + H(+) + NADPH


name: Activated FGFR2 phosphorylates PLCG1 (Drosophila melanogaster)


name: structural constituent of ascospore wall


name: Aquaporins passively transport urea into cells (Sus scrofa)


name: SIRP gamma binds CD47 (Canis familiaris)


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Mus musculus)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Sus scrofa)


name: ATP + glycine + H(+) = diphosphate + glycyl-5'-AMP


name: VAV3 is a GEF for Rho/Rac family kinases (Canis familiaris)


name: acetylcholine receptor regulator activity


name: STIM1 binds TRPC1 forming STIM1:TRPC1 complex (Bos taurus)


name: geranylhydroquinone + O2 + reduced [NADPH--hemoprotein reductase] => 3''-hydroxygeranylhydroquinone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Assembly of hexameric IL-6 receptor (Rattus norvegicus)


name: PIAS4 SUMOylates TP53BP1 with SUMO1 (Gallus gallus)


name: Basigin binds MCT1, MCT3 and MCT4 (Rattus norvegicus)


name: MBTPS2 (S2P) cleaves CREB3L3 (Danio rerio)


name: H(+)(in) + K(+)(in) + Na(+)(out) + serotonin(out) => H(+)(out) + K(+)(out) + Na(+)(in) + serotonin(in)


name: Expression of cell division cycle 42 (Homo sapiens)


name: chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] <=> cholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol = 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: PSGs bind proteoglycans and TGF-beta1 (Bos taurus)


name: AFG3L2 binds mitochondrial matrix proteins (Rattus norvegicus)


name: D-galactose + ganglioside GM2 (d18:1(4E)/18:0) => ganglioside GM1 (d18:1(4E)/18:0) + H2O


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Homo sapiens)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Gallus gallus)


name: De novo formation of eIF2:GTP (Drosophila melanogaster)


name: SLC34A3 cotransports Pi, 2Na+ (Xenopus tropicalis)


name: a carboxylate + CoA + GTP => an acyl-CoA + GDP + phosphate


name: (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Xenopus tropicalis)


name: ribostamycin + UDP-N-acetyl-alpha-D-glucosamine => 2'''-acetyl-6'''-hydroxyneomycin C + H(+) + UDP


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: malonyl-CoA + rhaponticin = 6-O-malonyl-rhaponticin + CoA


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Rattus norvegicus)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a fatty acid + H(+)


name: Association of Emi1 with Cdh1 (Bos taurus)


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+) => [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate


name: BPI binds LPS on the bacterial surface (Homo sapiens)


name: SRD5A3 reduces pPNOL to DCHOL (Homo sapiens)


name: Exocytosis of azurophil granule lumen proteins (Drosophila melanogaster)


name: diphosphate + stellata-2,6,19-triene => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: N,N-dimethylglycine + S-adenosyl-L-methionine = glycine betaine + H(+) + S-adenosyl-L-homocysteine


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Canis familiaris)


name: CaMKK autophosphorylates in the nucleus (Rattus norvegicus)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Homo sapiens)


name: L-alanine(in) + L-methionine(out) => L-alanine(out) + L-methionine(in)


name: 2 flaviolin + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3,8'-biflaviolin + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: TRAIL:TRAIL Receptor Trimer:FADD complex binds procaspase-8 (Rattus norvegicus)


name: H2O + L-lysyl-[protein] + O2 => (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+)


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + ATP + CoA => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: Formation of the 43S pre-initiation complex (Saccharomyces cerevisiae)


name: ATP + H2O + L-ornithine(out) => ADP + H(+) + L-ornithine(in) + phosphate


name: 7-hydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => 7,8-dihydroxyflavone + S-adenosyl-L-methionine


name: 2-oxobutanoate + L-methionine = (2S)-2-aminobutanoate + 4-methylsulfanyl-2-oxobutanoate


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Rattus norvegicus)


name: GUK1 phosphorylates 6TGMP to 6TGDP (Sus scrofa)


name: 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] => CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Caenorhabditis elegans)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Caenorhabditis elegans)


name: Production of AA by iPLA2 upon FCGR activation (Drosophila melanogaster)


name: Caspase-mediated cleavage of Lamin B1 (Canis familiaris)


name: 2-demethylmenaquinol-13 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-tridecaprenyl diphosphate + H(+)


name: 16 ATP + 16 H2O + N2 + 4 reduced [flavodoxin] <=> 16 ADP + 18 H(+) + H2 + 2 NH4(+) + 4 oxidized [flavodoxin] + 16 phosphate


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Rattus norvegicus)


name: 1-acyl LPS is acylated to PS by LPSAT (Rattus norvegicus)


name: adenosine 3',5'-bisphosphate + H(+) + lithocholate sulfate => 3'-phosphoadenylyl sulfate + lithocholate


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol => a 1-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a triacylglycerol


name: Formation of the 19S regulatory particle lid (Saccharomyces cerevisiae)


name: Active ARF recruits coatomer (Sus scrofa)


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Homo sapiens)


name: 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-methionine => 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)


name: NTHL1 glycosylase mediated recognition and binding of thymine glycol (Homo sapiens)


name: diphosphate + octanoyl-AMP => ATP + H(+) + octanoate


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Xenopus tropicalis)


name: 2-oxoaldehyde dehydrogenase (NAD+) activity


name: SUMOylation of TFAP2C with SUMO1 (Bos taurus)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Sus scrofa)


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: a medium-chain (3R)-hydroxyacyl-CoA = a medium-chain (2E)-enoyl-CoA + H2O


name: HMGB1 release from cells (Dictyostelium discoideum)


name: LIG1 binds POLB at long-patch BER site (Canis familiaris)


name: 2 S-adenosyl-L-methionine + uroporphyrinogen III = H(+) + precorrin-2 + 2 S-adenosyl-L-homocysteine


name: 6-O-alpha-D-glucopyranosyl-D-fructose + H2O => alpha-D-glucose + D-fructose


name: acetyl-CoA + an arylamine = an N-acetylarylamine + CoA


name: a ganglioside Gal-GD1b + GDP-beta-L-fucose <=> a ganglioside Gal(Fuc)-GD1b + GDP + H(+)


name: 4,8-dimethylnonanoyl-CoA + H2O => 4,8-dimethylnonanoate + CoA + H(+)


name: oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Saccharomyces cerevisiae)


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Rattus norvegicus)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Dictyostelium discoideum)


name: [cypemycin](1-18)-L-Cys-L-Leu-L-Val-L-Cys + A => AH2 + C(3,19),S(21)-[cypemycin](1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide + CO2 + hydrogen sulfide


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(8),N'(8)-citryl-bis(spermidine) => H(+) + holo-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine)


name: cAMP-dependent protein kinase inhibitor activity


name: DARPP-32 phosphorylated on Thr75 binds to PKA, inhibiting its function (Homo sapiens)


name: FUT3 transfers Fuc to Type 1 MSGG to form sLeA (Homo sapiens)


name: acetyl-CoA + 6 H(+) + 6 malonyl-CoA = 6 CO2 + 7 CoA + H2O + naphtopyrone YWA1


name: (R)-lactate + H(+) => H2O + methylglyoxal


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Rattus norvegicus)


name: CHEK1 is recruited to resected DNA DSBs (Homo sapiens)


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + 5-hydroxy-L-tryptophan => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Sus scrofa)


name: H2O + stipitatonate => CO2 + stipitatate


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Bos taurus)


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Rattus norvegicus)


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Caenorhabditis elegans)


name: Engulfed CpG DNA binds to endosomal full-length TLR9 (Bos taurus)


name: COQ3 methylates DHDB (Rattus norvegicus)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O => a 5'-end phospho-guanosine in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: 3-dehydro-L-gulonate + ATP = 3-dehydro-L-gulonate 6-phosphate + ADP + H(+)


name: 10-oxo-(11E)-octadecenoate + H(+) + NADH = 10-hydroxy-(11E)-octadecenoate + NAD(+)


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Relaxin receptor 1 binds relaxin 2 and 3 (Homo sapiens)


name: G3P is acylated to 1-acyl LPA by GPAM/GPAT2 (OM) (Danio rerio)


name: racemase and epimerase activity, acting on carbohydrates and derivatives


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Canis familiaris)


name: ASAH1 hydrolyzes ceramide (Rattus norvegicus)


name: ent-kaur-16-ene + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> ent-kaur-16-en-19-oate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: LRRC16A binds F-actin capping protein (Drosophila melanogaster)


name: 2-dehydro-D-glucose + glycine + H2O2 => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2


name: FBXL17 binds BACH1:MAFK (Drosophila melanogaster)


name: (2S-3S)-versiconal hemiacetal = H2O + versicolorin B


name: CHRM4 binds CHRM4 antagonists (Gallus gallus)


name: UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Homo sapiens)


name: Dephosphorylation of CK2-modified condensin I (Mus musculus)


name: Phosphorylated STAT1, STAT3 form dimers (Danio rerio)


name: UROD decarboxylates URO1 to COPRO1 (Schizosaccharomyces pombe)


name: ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Homo sapiens)


name: HYKK phosphorylates 5HLYS (Rattus norvegicus)


name: USP8 deubiquitinates FZD to potentiate WNT signaling (Bos taurus)


name: Apelin receptor binds to apelin (Gallus gallus)


name: Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation<br> (Homo sapiens)


name: 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 3 AH2 + CO2 + H(+) => 3 A + FMN + H2O + L-glutamate + O2


name: Recruitment of p190RhoGEF to p-FAK (Mus musculus)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Gallus gallus)


name: UV-DDB ubiquitinates XPC (Dictyostelium discoideum)


name: 5-methylcytidine(61) in tRNA(Asp) + H(+) + S-adenosyl-L-homocysteine => cytidine(61) in tRNA(Asp) + S-adenosyl-L-methionine


name: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O


name: TPST1,2 transfer SO4(2-) from PAPS to FVIII (Homo sapiens)


name: ATP + hexadecanoate + holo-[(hydroxy)phthioceranic acid synthase] = AMP + diphosphate + hexadecanoyl-[(hydroxy)phthioceranic acid synthase]


name: NEIL1 cleaves FapyA from damaged DNA (Bos taurus)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Bos taurus)


name: Dissociation of Cdc20 from APC/C complex (Dictyostelium discoideum)


name: SUMOylation of MDC1 with SUMO1 (Caenorhabditis elegans)


name: MAPK1-dependent phosphorylation of MITF-M (Gallus gallus)


name: PKC alpha interacts with and phosphorylates KIT (Rattus norvegicus)


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Sus scrofa)


name: NDUF subunits bind to form the IP subcomplex (Rattus norvegicus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Rattus norvegicus)


name: Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ADP + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP


name: Gamma-carboxy pro-protein C transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: H(+) + NADPH + pregnan-21-al => NADP(+) + pregnan-21-ol


name: PDK isozymes phosphorylate PDHC subunit E1 (Rattus norvegicus)


name: G-alpha(z):PKC dissociates to give phosphorylated G alpha (z) (Homo sapiens)


name: SUMOylation of NOP58 with SUMO2 (Gallus gallus)


name: GNRHR binds GNRHR peptide agonists (Xenopus tropicalis)


name: a 2'-deoxyribonucleoside 5'-phosphate + ATP = a 2'-deoxyribonucleoside 5'-diphosphate + ADP


name: 2-epi-5-epi-valiolone + phosphate => D-sedoheptulose 7-phosphate


name: (11Z)-hexadecenoyl-CoA + AH2 + O2 => (10E,12Z)-hexadecadienoyl-CoA + A + 2 H2O


name: a flavonol 3-O-beta-D-glucoside + UDP-beta-L-rhamnose = a flavonol 3-O-[alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + H(+) + UDP


name: RhCG mediates ammonium efflux out of kidney collecting duct cells (Danio rerio)


name: a 1,2-diacylglycerol + CoA => a 1-acylglycerol + an acyl-CoA


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Dictyostelium discoideum)


name: (+)-costunolide + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + parthenolide


name: 2-oxopentanoate + H2O2 + NH4(+) => H2O + L-2-aminopentanoate + O2


name: CDK2 phosphorylates TP53 (Drosophila melanogaster)


name: FMNL2 binds CDC42:GTP (Rattus norvegicus)


name: H2O + N(alpha)-methyl-L-tryptophan + O2 <=> formaldehyde + H2O2 + L-tryptophan


name: H(+)(out) + L-lysine(out) <=> H(+)(in) + L-lysine(in)


name: 2 (E)-sinapoyl-CoA + spermidine = 2 CoA + 2 H(+) + N(1),N(8)-bis[(E)-sinapoyl]-spermidine


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+) => (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein]


name: adenosine 3',5'-bisphosphate + an alkyl sulfate + H(+) => 3'-phosphoadenylyl sulfate + an alcohol


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Rattus norvegicus)


name: MAOB inhibitors bind MAOB:FAD (Danio rerio)


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Rattus norvegicus)


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + O-phospho-L-seryl-[protein] <=> 1D-myo-inositol hexakisphosphate + O-diphospho-L-seryl-[protein]


name: 2,5-dihydroxybenzoyl-CoA + H2O <=> 2,5-dihydroxybenzoate + CoA + H(+)


name: Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Homo sapiens)


name: Proteasome mediated degradation of COP1 (Rattus norvegicus)


name: DERA cleaves dR5P to GA3P and CH3CHO (Bos taurus)


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Canis familiaris)


name: (13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + H(+) + malonyl-CoA = 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + CO2 + CoA


name: Trans-homophilic interaction of PECAM-1 (Sus scrofa)


name: AGT(34-41) binds to AGTR2 (Rattus norvegicus)


name: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Schizosaccharomyces pombe)


name: H(+) + N,N-dihydroxy-L-tyrosine => (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + H2O


name: Dissociation of the Antigenic peptide:MHC:B2M peptide loading complex (Bos taurus)


name: Defective KHK does not phosphorylate beta-D-fructose (Homo sapiens)


name: cyclohexylamine + H2O + O2 = cyclohexanone + H2O2 + NH4(+)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = daturadiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + heptanoate + NADH => H2O + heptanal + NAD(+)


name: Inactivation of APC/C via CDC20 sequestration (Canis familiaris)


name: 2-oxoglutarate + dodecanoyl-CoA + O2 <=> 2-hydroxydodecanoyl-CoA + CO2 + succinate


name: adenylyl-sulfate reductase (thioredoxin) activity


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphoethanolamine + acetate + H(+)


name: Exocytosis of azurophil granule lumen proteins (Caenorhabditis elegans)


name: 4-hydroxyphenyl-[4-hydroxyphenylalkanoate synthase] + 24 H(+) + 8 malonyl-CoA + 16 NADPH = 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate synthase] + 8 CO2 + 8 CoA + 8 H2O + 16 NADP(+)


name: alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase]


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Bos taurus)


name: 4-hydroxybutanoyl-CoA + AMP + diphosphate => 4-hydroxybutanoate + ATP + CoA


name: LDLR:LDL complex => LDLR + LDL (Homo sapiens)


name: HSPA8:LAMP2a multimers depolymerizes to monomers (Homo sapiens)


name: PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Mus musculus)


name: (2E,6E)-farnesyl diphosphate = cis-muurola-3,5-diene + diphosphate


name: 3''-O-acetyl-ADP-D-ribose + H2O <=> acetate + ADP-D-ribose + H(+)


name: 3-oxotetracosanoyl-CoA + H(+) + NADPH <=> (3R)-hydroxytetracosanoyl-CoA + NADP(+)


name: 3-oxosphinganine + a fatty acyl-CoA => CoA + H(+) + N-acyl-3-oxosphinganine


name: H(+)(out) + N-acetylneuraminate(out) => H(+)(in) + N-acetylneuraminate(in)


name: 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-pyrrolidin-2-one + O2 <=> 5-[(4-hydroxyphenyl)methyl]-3-imino-4,4-dimethylpyrrolidin-2-one + H(+) + H2O2


name: 3-phenylpyruvate + H2O2 + NH4(+) => D-phenylalanine + H2O + O2


name: IL21 receptor JAK phosphorylation (Sus scrofa)


name: HSP70 binds to HSP40:nascent protein (Dictyostelium discoideum)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Drosophila melanogaster)


name: ROS oxidize thioredoxin (Rattus norvegicus)


name: FAD + H(+) + trans,octa-cis-decaprenylphospho-beta-D-ribofuranose => FADH2 + trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose


name: SUCLG1/A2 cleaves succinyl-CoA (Canis familiaris)


name: Formation of the Flap Intermediate (Caenorhabditis elegans)


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Rattus norvegicus)


name: Activated PKC-alpha  activate MMP3 (Rattus norvegicus)


name: 2-oxoglutarate + neomycin C <=> 6'''-deamino-6'''-oxoneomycin C + L-glutamate


name: PKCdelta phosphorylates HuR (Sus scrofa)


name: PDGF-AA clevage by Furin (Canis familiaris)


name: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine <=> 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine


name: 14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD(+) <=> 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + H(+) + NADH


name: Neuromedin-U receptors bind neuromedins U, S (Mus musculus)


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Sus scrofa)


name: 2-(9Z-octadecenoyl)-glycerol + phosphate => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + O2 => an N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: NFE2L2 dependent ABCF2 expression (Homo sapiens)


name: H(+)(in) + L-tryptophan(in) => H(+)(out) + L-tryptophan(out)


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: A4GNT transfers GlcNAc to core 2 mucins (Xenopus tropicalis)


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Mus musculus)


name: a fatty acyl-CoA + sphinga-(4E,8E)-dienine = an N-acyl-sphinga-4,8-dienine + CoA + H(+)


name: 13,14-dihydro-15-oxo-prostaglandin F1alpha + NADP(+) <=> 15-oxoprostaglandin F1alpha + H(+) + NADPH


name: ROS,RNS oxidize ACO2:4Fe-4S (Homo sapiens)


name: cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine => 5-methylcytidine(72) in tRNA(Thr) + H(+) + S-adenosyl-L-homocysteine


name: an omega-oxo fatty acid + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => an omega-hydroxy fatty acid + O2 + reduced [NADPH--hemoprotein reductase]


name: p75NTR:NADE promotes caspase2/3 activation (Bos taurus)


name: SLC35D2 exchanges UDP-D-glucose for UMP (Bos taurus)


name: p38 MAPK activation by VEGFR (Danio rerio)


name: a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + H2O <=> a di-trans,poly-cis-dolichyl phosphate + D-mannose + H(+)


name: a medium-chain (2E)-enoyl-CoA + H2O => a medium-chain (3S)-3-hydroxyacyl-CoA


name: H2O + N-tetracosanoyl-taurine => taurine + tetracosanoate


name: Formation of MSH1:PMS2 Complex (Gallus gallus)


name: S-adenosyl-L-homocysteine + S-methyl-L-methionyl-[protein] => L-methionyl-[protein] + S-adenosyl-L-methionine


name: eicosanoyl-CoA + H(+) + malonyl-CoA = 3-oxodocosanoyl-CoA + CO2 + CoA


name: D-sedoheptulose 1,7-bisphosphate + H2O <=> D-sedoheptulose 7-phosphate + phosphate


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Homo sapiens)


name: (R)-salsolinol + S-adenosyl-L-methionine => H(+) + N-methyl-(R)-salsolinol + S-adenosyl-L-homocysteine


name: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H(+)


name: a (2R,3S,4S)-leucoanthocyanidin + NADP(+) = a (2R,3R)-dihydroflavonol + H(+) + NADPH


name: (R)-4'-phospho-S-sulfopantetheine + H2O <=> (R)-S-sulfopantetheine + phosphate


name: Formation of pre-mRNPs (Canis familiaris)


name: P2Y6 receptor can bind to UDP (Bos taurus)


name: S100A8:S100A9 binds TLR4:LY96 (Rattus norvegicus)


name: Gq activation by TP receptor (Xenopus tropicalis)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in) => 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out)


name: LPL hydrolyses TGs from mature CMs (Canis familiaris)


name: glutathione S-conjugate carboxypeptidase activity


name: RHD gene produces PALM-C-Rhesus D protein (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 <=> (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate


name: neurotransmitter transmembrane transporter activity


name: Signal peptidase hydrolyzes preproGIP to proGIP (Homo sapiens)


name: PKR binds activating host RNA (Caenorhabditis elegans)


name: SRC,FYN phosphorylate NTRK2 (Homo sapiens)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Mus musculus)


name: dodecanamide + H2O => dodecanoate + NH4(+)


name: 3-methylthiopropyl glucosinolate S-oxygenase activity


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Xenopus tropicalis)


name: H2O + O2 + spermine = H2O2 + NH4(+) + spermine monoaldehyde


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Bos taurus)


name: VTN binds Plasminogen activator inhibitor- 1 (Mus musculus)


name: a sphingomyelin(in) = a sphingomyelin(out)


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + octadecanoate


name: Formation of Classical C3 convertase (C4b:C2a complex) (Xenopus tropicalis)


name: Src kinases phosphorylate VAV (Sus scrofa)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Dictyostelium discoideum)


name: 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) activity


name: L-quinate + NAD(+) = 3-dehydroquinate + H(+) + NADH


name: CS acetylates OA to citrate (Drosophila melanogaster)


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Homo sapiens)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Caenorhabditis elegans)


name: PPM1L dephosphorylates multiphospho-CERT1-2 (Drosophila melanogaster)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Homo sapiens)


name: UDP-glucose is oxidised to UDP-glucuronate (Homo sapiens)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Homo sapiens)


name: RNASEL cleaves cellular ssRNA (Gallus gallus)


name: JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Bos taurus)


name: JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Canis familiaris)


name: Activated FGFR1 binds PLCG1 (Rattus norvegicus)


name: (2E)-hexadecenoyl-CoA + H(+) + NADPH = hexadecanoyl-CoA + NADP(+)


name: [thyroglobulin]-3-iodo-L-tyrosine + H(+) + H2O2 + iodide = [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O


name: Integrin alpha5beta1 binds FN1 dimer (Sus scrofa)


name: androst-4-ene-3,17-dione + H(+) + NADPH <=> 5beta-androstane-3,17-dione + NADP(+)


name: Zinc is an agonist of GPR39 (Gallus gallus)


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Sus scrofa)


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Saccharomyces cerevisiae)


name: 4 H2O + O2 + 4 sulfur = 6 H(+) + 2 hydrogen sulfide + 2 sulfite


name: NAD(+) + trans-4-hydroxycyclohexane-1-carboxylate => 4-oxocyclohexane-1-carboxylate + H(+) + NADH


name: H2O + methylamine + O2 <=> formaldehyde + H2O2 + NH4(+)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Caenorhabditis elegans)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH


name: Association of cell cycle proteins with the APC/C:Cdh1 complex (Dictyostelium discoideum)


name: Carbonic anhydrase hydrates carbon dioxide (plasma membrane) (Rattus norvegicus)


name: a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + H(+) + UDP


name: EPHA binds TIAM1 (Caenorhabditis elegans)


name: stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential


name: 2,3-dioxo-L-gulonate(in) + Na(+)(in) = 2,3-dioxo-L-gulonate(out) + Na(+)(out)


name: IL18:IL18R1 binds IL18RAP (Homo sapiens)


name: 5-methylphenazine-1-carboxylate 1-monooxygenase (NADH) activity


name: PRKACA phosphorylates PLN (Homo sapiens)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Mus musculus)


name: PIAS1 SUMOylates THRB with SUMO1 (Bos taurus)


name: lithocholate + PAPS => lithocholate sulfate + PAP (Bos taurus)


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)


name: 5alpha-androstan-3,17-dione + A <=> 5alpha-androst-1-ene-3,17-dione + AH2


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Bos taurus)


name: CPN, CPB2 cleave C3a, C5a (Xenopus tropicalis)


name: a quinone + H2O + selenite <=> a quinol + selenate


name: cytidine(50) in tRNA + S-adenosyl-L-methionine => 5-methylcytidine(50) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: Hydrolysis of choloyl-CoA to cholate and CoASH (Danio rerio)


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Homo sapiens)


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Danio rerio)


name: 2 H(+)(out) + histamine(in) = 2 H(+)(in) + histamine(out)


name: EPH receptors autophosphorylate (Homo sapiens)


name: Anthrax lef cleaves target cell MAP2K7 (MEK7) (Homo sapiens)


name: 2-methylpropanenitrile + O2 + reduced [NADPH--hemoprotein reductase] <=> 2-hydroxy-2-methylpropanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 10-hydroperoxy-(8Z,11Z,14Z)-eicosatrienoate => (8Z,11Z,14Z)-eicosatrienoate + O2


name: (9Z)-octadecenoate + O2 => (8R)-hydroperoxy-(9Z)-octadecenoate


name: an (11Z,14Z)-icosadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) <=> H(+) + L-glutamyl-tRNA(Glu) + NADPH


name: a (Z)-N-(sulfonatooxy)alkenimidothioate <=> an alkenyl isothiocyanate + sulfate


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Bos taurus)


name: a ganglioside GA2 (d18:1(4E)) + H(+) + UDP => a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: (R)-glycerate + ADP-alpha-D-glucose => (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + ADP + H(+)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) => 5-amino-1-(beta-D-ribosyl)imidazole + ATP


name: a long-chain fatty acyl-AMP + holo-[mycocerosate synthase] = AMP + H(+) + long-chain fatty acyl-[mycocerosate synthase]


name: p-Y705-STAT3, p-Y641-STAT6 dimerise (Dictyostelium discoideum)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate <=> (S)-3-methyl-2-oxopentanoate + H2O


name: DFF dissociates from importin-alpha:importin-beta (Xenopus tropicalis)


name: phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] = (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit]


name: "C-phycoerythrin beta-cysteine-48/59 phycoerythrobilin lyase"


name: p-NICD1 PEST domain mutants do not bind FBXW7 (Homo sapiens)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Sus scrofa)


name: MAPK8 phosphorylation (Rattus norvegicus)


name: Autoglucosylation of GYG2 complexed with GYS2-a (Homo sapiens)


name: BRAP binds KSR1:MARK3 (Plasmodium falciparum)


name: acetyl-CoA + butanoate <=> acetate + butanoyl-CoA


name: SLCO4C1 mediates the transport of digoxin (Homo sapiens)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O = (6S)-5,6,7,8-tetrahydrofolate + formaldehyde


name: (3S)-3-hydroxy-L-aspartyl-[ankyrin-repeat domain protein] + CO2 + succinate => 2-oxoglutarate + L-aspartyl-[ankyrin-repeat domain protein] + O2


name: 2-methylbutan-1-ol + hexanoyl-CoA <=> 2-methylbutyl hexanoate + CoA


name: 3-hydroxy-2-methylpropanoate + CoA + H(+) => 3-hydroxy-2-methylpropanoyl-CoA + H2O


name: NEIL3 recognizes and binds to thymine glycol in telomeric DNA (Homo sapiens)


name: a di-trans,poly-cis-dolichol + NAD(+) = a di-trans,poly-cis-dolichal + H(+) + NADH


name: ubiquitin-like protein peptidase activity


name: Loading of dopamine into synaptic veiscles (Drosophila melanogaster)


name: RANBP2 SUMOylates SP100 with SUMO1 (Rattus norvegicus)


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Canis familiaris)


name: H2 + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: p-S54-PDE4B hydrolyses cAMP (Caenorhabditis elegans)


name: H(+) + 2 pyruvate <=> (2S)-2-acetolactate + CO2


name: p130Cas and C3G bind PDGFR bound Crk (Rattus norvegicus)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Mus musculus)