name: (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2 => 18S-resolvin E2 + A + H2O


name: a sterol + UDP-alpha-D-glucose <=> a sterol 3-beta-D-glucoside + H(+) + UDP


name: (-)-alpha-cuprenene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] => 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RHCE gene produces Rhesus C or E proteins (Homo sapiens)


name: acetyl-CoA + anthranilate => CoA + N-acetylanthranilate


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Dictyostelium discoideum)


name: Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Schizosaccharomyces pombe)


name: FNTA:FNTB transfers FARN to GNGT1 (Homo sapiens)


name: H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine


name: H2O + substance P <=> L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-6)


name: 10-deoxysarpagine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + sarpagine


name: CDP-glycerol + H2O <=> CMP + 2 H(+) + sn-glycerol 3-phosphate


name: Activated FGFR3 phosphorylates FRS2 (Rattus norvegicus)


name: an N-(1,2 saturated very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(III)-[cytochrome b5] + H2O


name: Parkin transfers Ub to misfolded proteins (Canis familiaris)


name: FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4 (Homo sapiens)


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Sus scrofa)


name: Interaction of PECAM-1 and SHIP (Rattus norvegicus)


name: Loss-of-function DLD mutants don't dehydrogenate dihydrolipoyl DBT (Homo sapiens)


name: Defective MyD88 does not bind MAL(TIRAP):TLR2/4 (Homo sapiens)


name: Degradation of ubiquitinated beta catenin by the proteasome (Bos taurus)


name: beta-D-galactosyl-(1<->1)-sphing-4-enine + H2O = D-galactose + sphing-4-enine


name: Dephosphorylation of pChREBP (Ser 196) by PP2A (Homo sapiens)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Mus musculus)


name: H(+)(in) + L-arabinose(out) => H(+)(out) + L-arabinose(in)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + CMP-N-acetyl-beta-neuraminate <=> [N-acetyl-alpha-D-neuraminosyl-(2->8)](n+1) + CMP + H(+)


name: 3-oxodecanoyl-CoA + H(+) + NADPH => (3R)-3-hydroxydecanoyl-CoA + NADP(+)


name: CASP8 cleaves N4BP1 at D424, D490 (Sus scrofa)


name: loganate + S-adenosyl-L-methionine = loganin + S-adenosyl-L-homocysteine


name: Beta-tubulin:GTP:Cofactor D:alpha-tubulin:GTP:Cofactor E:Cofactor C-> Beta-tubulin:GDP :alpha-tubulin:GTP heterodimer +Cofactor E+ Cofactor D+ Cofactor C+ Pi (Homo sapiens)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Sus scrofa)


name: DENND6A,B exchange GTP for GDP on RAB14 (Drosophila melanogaster)


name: (R)-2-benzylsuccinyl-CoA + succinate => (R)-2-benzylsuccinate + succinyl-CoA


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Bos taurus)


name: Egress of internalized antigen into cytosol from early endosome (Homo sapiens)


name: Cu(+)(out) + H(+) + monodehydro-L-ascorbate radical(in) => Cu(2+)(out) + L-ascorbate(in)


name: Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Homo sapiens)


name: a quinone + butan-1-ol = a quinol + butanal


name: mycophenolic acid O-acyl-beta-D-glucuronide + UDP => mycophenolate + UDP-alpha-D-glucuronate


name: IkB is ubiquitinated and degraded (Xenopus tropicalis)


name: glycine + urea => guanidinoacetate + H2O


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Canis familiaris)


name: Ubiquitinated Orc1 is degraded by the proteasome (Canis familiaris)


name: a 5'-end diphospho-guanosine in mRNA + GTP + H(+) <=> a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + diphosphate


name: 3-methylbutanoate + CoA + H(+) => 3-methylbutanoyl-CoA + H2O


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phospho-L-serine


name: a beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosaminyl derivative + H(+) + UDP => a beta-D-galactosyl-(1->4)-beta-D-glucosyl derivative + UDP-alpha-D-galactose


name: Molybdenum ion transfer onto molybdopterin (Homo sapiens)


name: Superoxide and nitric oxide react to peroxynitrite in the phagosome (Homo sapiens)


name: MIR449 microRNAs bind 3'UTR of NOTCH1 mRNA (Homo sapiens)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Caenorhabditis elegans)


name: (13Z)-docosenamide + H2O => (13Z)-docosenoate + NH4(+)


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Caenorhabditis elegans)


name: Dephosphorylation of STAT1 by SHP2 (Mus musculus)


name: A + H2O + uracil => AH2 + barbiturate + H(+)


name: RhoGTPase GEF's recruited to DCC (Rattus norvegicus)


name: (6E)-8-hydroxygeranial + NADP(+) = (6E)-8-oxogeranial + H(+) + NADPH


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Mus musculus)


name: [(1->4)-alpha-D-galacturonosyl](n) + H2O <=> [(1->4)-alpha-D-galacturonosyl](n-2) + alpha-D-galacturonosyl-(1->4)-D-galacturonate


name: SGK phosphorylates SRF (Caenorhabditis elegans)


name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate <=> all-trans-heptaprenyl diphosphate + 4 diphosphate


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Bos taurus)


name: a 3-dehydro-D-glucoside + 2 Fe(II)-[cytochrome c] + 2 H(+) => a D-glucoside + 2 Fe(III)-[cytochrome c]


name: L-tetrahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (E)-7-(methylsulfanyl)heptanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Electron transfer from ubiquinol to cytochrome c of complex III (Sus scrofa)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Caenorhabditis elegans)


name: acetyl-CoA(out) + AMP(in) => acetyl-CoA(in) + AMP(out)


name: (R)-2-hydroxy-3-methylbutyrate + NADP(+) => 3-methyl-2-oxobutanoate + H(+) + NADPH


name: Keratin tetramers bind to form unit length filaments (Canis familiaris)


name: Activation of MT-MMPs by FURIN (Mus musculus)


name: (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Dictyostelium discoideum)


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Xenopus tropicalis)


name: 1,3,8-trihydroxynaphthalene + H2O => scytalone


name: ATP + CoA + pentanoate = AMP + diphosphate + pentanoyl-CoA


name: MET bound PI3K generates PIP3 (Bos taurus)


name: PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) (Sus scrofa)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: 2 (4Z,15Z)-bilirubin IXalpha + O2 = 2 biliverdin IXalpha + 2 H2O


name: Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA (Homo sapiens)


name: L-cysteine + S-sulfanyl-L-cysteine => L-alanine + S-disulfanyl-L-cysteine


name: (R)-carnitine(out) + O-acetyl-(R)-carnitine(in) => (R)-carnitine(in) + O-acetyl-(R)-carnitine(out)


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Mus musculus)


name: 1-O-(13-methyltetradecyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 1-O-(1Z-13-methyltetradecenyl)-2-(13-methyltetradecanoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 11-deoxycortisol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PAF receptor binds platelet activating factor (Mus musculus)


name: 1D-myo-inositol 1,4,5-trisphosphate + phosphate => 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O


name: (2E)-thiogeraniol + 5-methylaminomethyl-2-selenouridine(34) in tRNA + diphosphate + phosphate => (2E)-geranyl diphosphate + 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + H2O + selenophosphate


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Rattus norvegicus)


name: CALR, TAP, TAPBP dissociate from SEC22B:STX4 (Bos taurus)


name: Caspase-8 and FLIP(L) processing at DISC (Homo sapiens)


name: NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates (Homo sapiens)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the early endosome membrane (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O => 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+) + hexadecanoate


name: Thyrotropin is a heterodimer (Gallus gallus)


name: nitric oxide + superoxide => peroxynitrite


name: D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH


name: RNA polymerase I transcription regulatory region sequence-specific DNA binding


name: STAT binds to the active receptor (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Saccharomyces cerevisiae)


name: PON1,3 hydrolyse ATVL to ATV (Xenopus tropicalis)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Sus scrofa)


name: (2E,18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontaheptaenoyl-CoA + H(+) + NADPH => (18Z,21Z,24Z,27Z,30Z,33Z)-hexatriacontahexaenoyl-CoA + NADP(+)


name: Formation of the RBBP5:ASH2L heterodimer (Plasmodium falciparum)


name: dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine = dTDP-alpha-D-desosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: BCDX2 complex stabilizes RAD51 filament (Bos taurus)


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Homo sapiens)


name: Liganded Gs-activating GPCR acts as a GEF for Gs (Caenorhabditis elegans)


name: NOX4, NOX5 reduce O2 to O2.- (Drosophila melanogaster)


name: H2O + N(6)-acetyl-L-lysyl-[protein] + O2 => (S)-2-amino-6-oxohexanoyl-[protein] + acetamide + H2O2


name: KCTD6 gene expression is stimulated by RUNX1 and ESR1 (Homo sapiens)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Saccharomyces cerevisiae)


name: POLD,POLE-mediated DNA strand displacement synthesis (Sus scrofa)


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + ATP <=> 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + ADP + H(+)


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Canis familiaris)


name: chloride(out) + 2 Na(+)(out) + taurine(out) => chloride(in) + 2 Na(+)(in) + taurine(in)


name: NK13650 B + S-adenosyl-L-methionine <=> H(+) + NK13650 D + S-adenosyl-L-homocysteine


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Bos taurus)


name: PINK1 is autophosphorylated (Danio rerio)


name: H2O + N(6)-hexanoyl-L-lysyl-[protein] + NAD(+) => 2''-O-hexanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: (E)-2-methylpropanal oxime => (Z)-2-methylpropanal oxime


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Bos taurus)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Sus scrofa)


name: H(+) + L-arogenate => CO2 + H2O + L-phenylalanine


name: 1-chloro-3-nitrobenzene + NADH + O2 = 3-chlorocatechol + NAD(+) + nitrite


name: H(+) + NADH + pregnan-21-al => NAD(+) + pregnan-21-ol


name: AXL autophosphorylates on Y779 and Y821 (Rattus norvegicus)


name: PTK6 phosphorylates ARAP1 (Homo sapiens)


name: 2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate <=> 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 2-phenylacetate + ATP + CoA => AMP + diphosphate + phenylacetyl-CoA


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Danio rerio)


name: 2-hydroxy-3-oxosuccinate + H(+) + NADH => NAD(+) + tartrate


name: RAB4:GTP promotes recycling of activated MET receptor to the plasma membrane (Mus musculus)


name: Translocation of PDK1 to Plasma membrane (Mus musculus)


name: SLC6A15-mediated amino acid uptake (Plasmodium falciparum)


name: 2 H(+) + O2 + pentalenene + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-ol


name: GNE phosphorylates ManNAc to ManNAc-6-P (Xenopus tropicalis)


name: 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine => 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: lithocholate + PAPS => lithocholate sulfate + PAP (Xenopus tropicalis)


name: CYP3A4, CYP2B6 bind ritonavir (Drosophila melanogaster)


name: H2O + neurotensin => L-leucine + neurotensin-(1-12)


name: chloride + S-adenosyl-L-methionine = 5'-chloro-5'-deoxyadenosine + L-methionine


name: 1,3,5-trihydroxybenzene + H(+) + phloretate => H2O + phloretin


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Drosophila melanogaster)


name: Release of acetylcholine at the synapse (Drosophila melanogaster)


name: a ribonucleotide in rRNA + S-adenosyl-L-methionine <=> a 2'-O-methylribonucleotide in rRNA + H(+) + S-adenosyl-L-homocysteine


name: n H(+)(out) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) <=> n H(+)(in) + N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP


name: SHC1 binds phosphorylated ERBB2 homodimer (Homo sapiens)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (5S)-hydroperoxy-(14R,15S)-epoxy-(6E,8Z,11Z)-eicosatrienoate


name: PLEKHA3,8 bind PI4P, ARF1 (Homo sapiens)


name: PIAS1,3 SUMOylate NRIP1 with SUMO1 (Bos taurus)


name: (E,E)-piperoyl-CoA + pyrrolidine <=> CoA + H(+) + piperyline


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Bos taurus)


name: 5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al (Sus scrofa)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 <=> (2E,5Z,8Z,11Z,14Z,17Z)-icosahexaenoyl-CoA + H2O2


name: 2 a Fe(III)-siderophore + NADPH => 2 a Fe(II)-siderophore + H(+) + NADP(+)


name: PDPK1 phosphorylates RSKs (Homo sapiens)


name: FUT2 transfers Fuc to Type 1 chains to form H antigen-sec (Caenorhabditis elegans)


name: (2S)-4-acetamido-2-aminobutanoate + CoA + H(+) => acetyl-CoA + L-2,4-diaminobutanoate


name: Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding (Homo sapiens)


name: Vanin hydrolyses pantetheine to PanK, 2AET (Homo sapiens)


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Saccharomyces cerevisiae)


name: 3,3',5-trihydroxybibenzyl + 4 CO2 + 4 CoA => 3-(3-hydroxyphenyl)-propanoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: ATP + histamine + L-glutamate => ADP + H(+) + N(alpha)-gamma-L-glutamylhistamine + phosphate


name: C5 binds C5 inhibitors (Canis familiaris)


name: 5,6,7,8-tetrahydropteridine + NADP(+) => 6,7-dihydropteridine + H(+) + NADPH


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-6-aminohexanoate + O2 => (1-deoxy-D-fructos-1-yl)amine + 6-oxohexanoate + H2O2


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Rattus norvegicus)


name: (S)-2-hydroxypropylphosphonate + H2O2 => (1R,2S)-epoxypropylphosphonate + 2 H2O


name: MST1 dimer:MST1R dimer binds MST1R dimer (Danio rerio)


name: FLIP(L) and procaspase-8 form heterodimer (Canis familiaris)


name: 3-(3,4-dichlorophenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => diuron + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: (2E,6E)-farnesyl phosphate + CTP = (2E,6E)-farnesyl diphosphate + CDP


name: ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 (Canis familiaris)


name: diphosphate + icosanoyl-AMP => ATP + eicosanoate + H(+)


name: CHSY1 transfers GlcA to chondroitin (Sus scrofa)


name: (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + NADH


name: a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a 1,2-diacyl-sn-glycerol => 2 a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: (S)-carnitine(out) + Na(+)(out) => (S)-carnitine(in) + Na(+)(in)


name: TRPM4,5 transport extracellular Na+ to cytosol (Mus musculus)


name: (1R,5S)-carveol + NAD(+) => (S)-carvone + H(+) + NADH


name: SPN27A binds to and inhibits EA protease activity (Drosophila melanogaster)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Gallus gallus)


name: beta-D-fructofuranosyl alpha-D-mannopyranoside 6(F)-phosphate + H2O => beta-D-fructofuranosyl alpha-D-mannopyranoside + phosphate


name: ITPA dimer dephosphorylates RBV-TP to RBV-MP (Canis familiaris)


name: PG and CDP-DAG are converted to CL by CRLS1 (Sus scrofa)


name: STAMBP binds STAM (Schizosaccharomyces pombe)


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Mus musculus)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: 2 H(+) + H2O + N-carbamoylsarcosine <=> CO2 + NH4(+) + sarcosine


name: CIDEA:CIDEC binds lipid droplets (Sus scrofa)


name: L-homoserine = 2-aminobut-2-enoate + H2O


name: 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + H2O => (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-3-hexadecanoyl-sn-glycerol + H(+)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Xenopus tropicalis)


name: (S,S)-butane-2,3-diol + NAD(+) = (S)-acetoin + H(+) + NADH


name: 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate = 16alpha,17alpha-estriol 17-O-(beta-D-glucuronate) + H(+) + UDP


name: H2O + N-formimidoyl-L-glutamate => N-formyl-L-glutamate + NH4(+)


name: H2O + L-tryptophan <=> indole + NH4(+) + pyruvate


name: H(+) + hydrogencarbonate + methylphosphonate => 2-hydroxyethylphosphonate + O2


name: 2 AH2 + all-trans-4,4'-diapolycopene-4,4'-dioate + 2 H(+) => 2 A + all-trans-4,4'-diapolycopene-4,4'-dial + 2 H2O


name: (E,E)-piperoyl-CoA + piperidine => CoA + H(+) + piperine


name: ent-7alpha-hydroxykaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] = gibberellin A12 aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Sus scrofa)


name: CoA + H(+) + N-hexacosanoylglycine => glycine + hexacosanoyl-CoA


name: DENND4s exchange GTP for GDP on RAB10 (Canis familiaris)


name: MEN1 binds SMAD2/3:SMAD4 heterotrimer (Bos taurus)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Schizosaccharomyces pombe)


name: Removal of siRNA passenger strand (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH => 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: 5,12-dihydroxanthommatin + NAD(+) <=> H(+) + NADH + xanthommatin


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Caenorhabditis elegans)


name: Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Canis familiaris)


name: CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 (Homo sapiens)


name: a dicarboxylate(in) + kynurenate(out) <=> a dicarboxylate(out) + kynurenate(in)


name: cyclo(L-phenylalanyl-L-leucyl) + 2 O2 <=> albonoursin + 2 H2O2


name: CO2 + UDP-beta-L-arabinopyranose => H(+) + UDP-alpha-D-galacturonate


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Saccharomyces cerevisiae)


name: succinate + ubiquinone-8 => fumarate + ubiquinol-8


name: TGFBR3(784-851) degradation (Canis familiaris)


name: Ubiquitinated AXIN is degraded by the proteasome (Mus musculus)


name: L-phenylalanine + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-hydroxy-L-phenylalanine + oxidized [NADPH--hemoprotein reductase]


name: a 4-saturated-(3S)-3-hydroxyacyl-CoA <=> a (3E)-enoyl-CoA + H2O


name: SUMOylation of NR3C1 (GR) with SUMO1 (Rattus norvegicus)


name: 3,5-dimethylcyclohexanone + H(+) + NADPH + NH4(+) => 3,5-dimethylcyclohexanamine + H2O + NADP(+)


name: (24R)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (24R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Homo sapiens)


name: 2-(prostaglandin G2)-sn-glycero-3-phosphocholine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphocholine + A + H2O


name: (2Z)-2-hydroxypenta-2,4-dienoate + acetate + H(+) => (2Z,4E)-2-hydroxy-6-oxohepta-2,4-dienoate + H2O


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Mus musculus)


name: PELI1 ubiquitinates RIPK3 at K363 (Rattus norvegicus)


name: (1S)-1-hydroxy-luvungin A + acetyl-CoA <=> (1S)-1-acetoxy-luvungin A + CoA


name: ALDH7A1 oxidises BETALD to BET (Bos taurus)


name: 2xPPCS ligates PPanK with Cys (Rattus norvegicus)


name: chloride(out) + iodide(in) => chloride(in) + iodide(out)


name: (2R,4S)-2,4-diaminopentanoate + H2O + NADP(+) = (2R)-2-amino-4-oxopentanoate + H(+) + NADPH + NH4(+)


name: 2-methoxybenzoate + ATP + H(+) + NADPH <=> 2-methoxybenzaldehyde + AMP + diphosphate + NADP(+)


name: PDX1-dependent synthesis of NKX6-1 protein (Homo sapiens)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Rattus norvegicus)


name: [aequorin]--dioxetanone = [excited state blue fluorescent protein] + CO2


name: an N-acyl-(4R)-4-hydroxysphinganine + H(+) + mannosyldiinositol-1-phosphate => an inositol phosphomannosylinositol-1-phospho-N-acyl-(4R)-4-hydroxysphinganine + H2O


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Canis familiaris)


name: p-T182 MAPKAPK5 binds DNAJB1 (Danio rerio)


name: a dicarboxylate(in) + N-benzoylglycine(out) => a dicarboxylate(out) + N-benzoylglycine(in)


name: prostaglandin E2 = H2O + prostaglandin A2


name: USP18 binds IKBKG within IKK complex (Mus musculus)


name: H2O + N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone => H(+) + N,N',N'',N'''-tetraacetylchitotetraonate


name: Aggresome dissociates from dynein and microtubule (Plasmodium falciparum)


name: 2,5-dicarboxyfuran + H(+) + H2O2 => 2-carboxy-5-(dihydroxymethyl)furan + O2


name: I4P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Rattus norvegicus)


name: PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)


name: CO2 + H2O + proviolacein => H(+) + O2 + protoviolaceinate


name: Ubiquitinated AXIN is degraded by the proteasome (Gallus gallus)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Danio rerio)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Xenopus tropicalis)


name: 6-oxohexanoate + H2O + NADP(+) => 2 H(+) + hexanedioate + NADPH


name: mRNA regulatory element binding translation repressor activity


name: RHOG translocates to the ER membrane (Gallus gallus)


name: a thiol + S-adenosyl-L-methionine = a methyl thioether + H(+) + S-adenosyl-L-homocysteine


name: P-type monovalent copper transporter activity


name: BLVRA:Zn2+, BLVRB reduce BV to BIL (Gallus gallus)


name: ALDH5A1 dehydrogenates SUCCSA to SUCCA (Rattus norvegicus)


name: diphosphate + phosphate => H2O + triphosphate


name: aphidicolan-16beta-ol + diphosphate => 9alpha-copalyl diphosphate + H2O


name: ATP + bisucaberin B => AMP + bisucaberin + diphosphate + H(+)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Xenopus tropicalis)


name: PDE3A inhibitors bind PDE3A (Dictyostelium discoideum)


name: Active Rac1 interacts with Plexin-B1:Sema4D (Bos taurus)


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Canis familiaris)


name: (S)-malyl N-acetyl-alpha-D-glucosaminide + H2O = (S)-malyl alpha-D-glucosaminide + acetate


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Gallus gallus)


name: Dimerization of PERK (Rattus norvegicus)


name: 2-hydroxyethane-1-sulfonate + NADP(+) <=> H(+) + NADPH + sulfoacetaldehyde


name: Autocatalytic activation of proMMP13 (Mus musculus)


name: 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP => 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: IQGAPs bind CALM1 (Caenorhabditis elegans)


name: SUMOylation of DDX17 with SUMO1 (Saccharomyces cerevisiae)


name: diphosphate + talarodiene => (2E,6E,10E)-geranylgeranyl diphosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 = (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate


name: H2O + N-terminal L-tryptophanyl-L-alpha-aminoacyl-[peptide] = L-tryptophan + N-terminal L-alpha-aminoacyl-[peptide]


name: (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphoglycerol + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoglycerol + H2O


name: Autophosphorylation of PAK1 (Saccharomyces cerevisiae)


name: Phospholipase C-gamma1 binds to the activated EGF receptor (Drosophila melanogaster)


name: ADP + beta-alanyl-L-arginine + H(+) + phosphate => ATP + beta-alanine + L-arginine


name: A + dodecanedioyl-CoA => (2E)-dodecenedioyl-CoA + AH2


name: long-chain fatty acid--protein ligase activity


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Canis familiaris)


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Mus musculus)


name: eNoSC deacetylates histone H3 (Rattus norvegicus)


name: NaS1 co-transports sulphate and a sodium ion (Caenorhabditis elegans)


name: SALM2 associate with AMPA and NMDA receptors (Drosophila melanogaster)


name: agroclavine + NADP(+) => didehydroagroclavine + H(+) + NADPH


name: RAC1 GAPs stimulate RAC1 GTPase activity (Homo sapiens)


name: The exocyst complex binds to RAB3IP in the ciliary targeting complex (Mus musculus)


name: (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate <=> 2-succinylbenzoate + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: D inhibits WTS (Drosophila melanogaster)


name: Collagen type II degradation by MMP15 (Canis familiaris)


name: 11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: 3-oxosphinganine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoyl-3-oxosphinganine


name: SUMOylation of UBE2I with SUMO1 (Gallus gallus)


name: a ganglioside GD1a (d18:1(4E)) + acetyl-CoA <=> a ganglioside Ac-O-7-GD1a (d18:1(4E)) + CoA


name: BCKDHA:BCKDHB tetramer decarboxylates KIC, KMVA, KIV (Dictyostelium discoideum)


name: COMT binds COMT Inhibitors (Xenopus tropicalis)


name: Formation of FACT complex (Saccharomyces cerevisiae)


name: NAT1,2 acetylate APAP-Cys to APAP-Mer (Rattus norvegicus)


name: ATP12A:ATP4B exchanges K+ for H+ (Mus musculus)


name: (R)-2-methyl-3-oxopropanoate + CoA + H2O + NAD(+) => H(+) + hydrogencarbonate + NADH + propanoyl-CoA


name: (11E,13Z)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (11E)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: L-glutamyl-[protein] + NAD(+) = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide


name: (9Z)-octadecenoyl-[ACP] + H2O = (9Z)-octadecenoate + H(+) + holo-[ACP]


name: myo-inositol + phosphate => 1D-myo-inositol 6-phosphate + H2O


name: DELE1(143-515) is released into the cytosol (Rattus norvegicus)


name: CHOL translocates from lysosome membrane to ER membrane (Mus musculus)


name: Phosphorylation of JAK2 (Canis familiaris)


name: PIAS2-2 SUMOylates THRA with SUMO1 (Mus musculus)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Rattus norvegicus)


name: GGPS1 hexamer transfers IPPP to DMAPP (Xenopus tropicalis)


name: H(+) + hexanoyl-CoA + malonyl-[ACP] <=> 3-oxooctanoyl-[ACP] + CO2 + CoA


name: a 5,6-dihydrouridine in mRNA + NADP(+) => a uridine in mRNA + H(+) + NADPH


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Danio rerio)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Bos taurus)


name: 3-hydroxybenzoyl-CoA + AH2 + 2 ATP + 2 H2O = 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA + A + 2 ADP + 2 H(+) + 2 phosphate


name: (1Z,2S)-2-methylbutanal oxime => (1E,2S)-2-methylbutanal oxime


name: glycine + phenylacetyl-CoA = CoA + H(+) + phenylacetylglycine


name: H2O + N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine => 4-amino-5-aminomethyl-2-methylpyrimidine + formate


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Sus scrofa)


name: ajmaline + H(+) + S-adenosyl-L-homocysteine => norajmaline + S-adenosyl-L-methionine


name: 13-cis-retinol + a fatty acid + H(+) => an all-trans-retinyl ester + H2O


name: VLDLR:PCSK9:Clathrin-coated vesicle translocates from the plasma membrane to lysosomal membrane (Schizosaccharomyces pombe)


name: (2E)-tetracosenoyl-CoA + H2O2 => O2 + tetracosanoyl-CoA


name: CAD hexamer transforms L-Gln to CAP (Homo sapiens)


name: The phagophore extends from the PIP3-enriched structure (Canis familiaris)


name: daunorubicin + H(+) + S-adenosyl-L-homocysteine => carminomycin + S-adenosyl-L-methionine


name: Progesterone Activation Of CatSper (Bos taurus)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR2:SBF1 (Bos taurus)


name: NEIL3 resolves abasic site-induced ICLs (Homo sapiens)


name: Recruitment of IFNAR1 (Canis familiaris)


name: CDKN1B is phosphorylated in response to estrogen (Danio rerio)


name: acetyl-[ACP] + CoA => acetyl-CoA + holo-[ACP]


name: 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH => L-threo-tetrahydrobiopterin + 2 NADP(+)


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Xenopus tropicalis)


name: EGR-dependent NAB2 gene expression (Homo sapiens)


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Caenorhabditis elegans)


name: glycocholate + L-histidine = glycine + L-histidocholate


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Sus scrofa)


name: 3 A + FMN + H2O + L-glutamate + O2 => 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 3 AH2 + CO2 + H(+)


name: bilirubin IXbeta + NADP(+) <=> biliverdin IXbeta + H(+) + NADPH


name: dodecanoyl-CoA + hexadecan-1-ol => CoA + hexadecanyl dodecanoate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-octadecanoyl-sn-glycero-3-phosphate + H(+) => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Schizosaccharomyces pombe)


name: Phosphorylation of YAP by LATS1 (Homo sapiens)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Mus musculus)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Homo sapiens)


name: ADP + H(+) + L-histidine(in) + phosphate => ATP + H2O + L-histidine(out)


name: (+)-copalyl diphosphate <=> (-)-pimara-8(14),15-diene + diphosphate


name: 4beta-carboxyl motiol + O2 + reduced [NADPH--hemoprotein reductase] => 2alpha-hydroxyl, 4beta-carboxyl motiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CO binds to Cytochrome c oxidase (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate](n) <=> adenosine 3',5'-bisphosphate + 2 H(+) + N-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n)


name: (3R)-3-[(carboxymethyl)amino]butanoate + H(+) + holo-[ACP] => (2E)-butenoyl-[ACP] + glycine + H2O


name: Cytosolic DUSPs dephosphorylate MAPKs (Rattus norvegicus)


name: PRODH2 oxidises HPRO to 1PYR-5COOH (Rattus norvegicus)


name: a beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H(+) => a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose


name: p-PKR dimer phosphorylates TP53 tetramer (Drosophila melanogaster)


name: 3-O-(alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + H(+) + UDP


name: 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: SCF:FBXL7 binds AURKA (Caenorhabditis elegans)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Canis familiaris)


name: SUMOylation of DDX5 with SUMO1 (Saccharomyces cerevisiae)


name: 2-oxoglutarate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] <=> CO2 + N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase]


name: GBF1 recruits ARF:GDP to the Golgi (Mus musculus)


name: Recruitment of POLB to the AP site (Rattus norvegicus)


name: AH2 + 2 N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline => A + 2 N(delta)-hydroxy-N(omega)-methyl-L-citrulline + 2 nitric oxide


name: 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + A = (2E)-3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]prop-2-enoyl-CoA + AH2


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Mus musculus)


name: CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 (Sus scrofa)


name: 2-hydroxy-7-methyl-6-oxo-(2E,4E)-octadienoate + CO2 => 3-carboxy-2-hydroxy-7-methyl-6-oxo-(2Z,4Z)-octadienoate + H(+)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1:NBR1 (Gallus gallus)


name: 9-hydroxy-octadecanoate + a triacylglycerol <=> 9-(acyloxy)-octadecanoate + a 1,3-diacylglycerol


name: RXRA:PPARD binds FABP5:atRA (Caenorhabditis elegans)


name: cholesterol + 6 H(+) + 3 O2 + 6 reduced [adrenodoxin] = 4-methylpentanal + 4 H2O + 6 oxidized [adrenodoxin] + pregnenolone


name: SREBP1A,1C,2 binds SREBP1A,1C,2 forming dimers (Bos taurus)


name: 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity


name: benzaldehyde + H2O + NADP(+) <=> benzoate + 2 H(+) + NADPH


name: beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + GDP-beta-L-fucose <=> beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-D-glucosamine + GDP + H(+)


name: Multiubiquitination of APC/C-associated Cdh1 (Bos taurus)


name: a 7(1)-hydroxybacteriochlorophyllide d + H2O + S-adenosyl-L-methionine => 5'-deoxyadenosine + a 7(1),7(1)-dihydroxybacteriochlorophyllide d + H(+) + L-methionine


name: (1S,2R,4R)-neoisodihydrocarveol + NAD(+) <=> (1S,4R)-isodihydrocarvone + H(+) + NADH


name: GLI proteins are phosphorylated (Homo sapiens)


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)


name: decanoyl-[ACP] + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = dec-9-ynoyl-[ACP] + 4 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: 3'-phosphoadenylyl sulfate(in) + adenosine 3',5'-bisphosphate(out) => 3'-phosphoadenylyl sulfate(out) + adenosine 3',5'-bisphosphate(in)


name: O-GlcNAcylation of RIPK3 (TLR4 signaling) (Bos taurus)


name: D-fructose + NADP(+) <=> 5-dehydro-D-fructose + H(+) + NADPH


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Sus scrofa)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Sus scrofa)


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 = 1-O-methyl-(13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: (6S)-NADPHX + ATP = ADP + H(+) + NADPH + phosphate


name: Tryptophan is hydroxylated (Rattus norvegicus)


name: Release of platelet cytosolic components (Sus scrofa)


name: Proteasome degrades polyubiquitinated PTEN (Drosophila melanogaster)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Rattus norvegicus)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SUMOylation of MDC1 with SUMO1 (Mus musculus)


name: MAPKAPK5 phosphorylates KALRN (Gallus gallus)


name: Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Mus musculus)


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Canis familiaris)


name: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Rattus norvegicus)


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Drosophila melanogaster)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Dictyostelium discoideum)


name: IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation  (Sus scrofa)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Homo sapiens)


name: Formation of the 19S regulatory particle lid (Xenopus tropicalis)


name: LMF1,2 transport LIPC dimer from ER lumen to extracellular region (Mus musculus)


name: GYS2 catalyzes the polyglucosylation of oligoGlc-GYG2 (Sus scrofa)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 3 O2 + 2 reduced [flavodoxin] <=> 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 3 H(+) + 3 H2O + 2 oxidized [flavodoxin]


name: Removal of remaining Flap (Mus musculus)


name: Association of procollagen type II (Gallus gallus)


name: Noradrenalin synaptic vesicle docking and priming (Mus musculus)


name: all-trans-retinol + hexadecanoyl-CoA <=> all-trans-retinyl hexadecanoate + CoA


name: 15-cis-phytoene + diphosphate => (1R,2R,3R)-prephytoene diphosphate


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex  (Sus scrofa)


name: ARFRP1 recruits ARL1 to the TGN (Xenopus tropicalis)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Rattus norvegicus)


name: CaMKK binds activated calmodulin in the cytosol (Homo sapiens)


name: RNA Polymerase II Promoter Opening: First Transition (Dictyostelium discoideum)


name: 7-deoxyloganetic alcohol + O2 + reduced [NADPH--hemoprotein reductase] => 7-deoxyloganetic aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: hexadecanoyl-CoA + octan-1-ol => CoA + octyl hexadecanoyl


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: BAP1 binds BAP1-interacting complex (Canis familiaris)


name: GRB2:SOS1 complex binds to the active receptor (Rattus norvegicus)


name: H2O + L-asparaginyl-[protein] <=> L-aspartyl-[protein] + NH4(+)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Homo sapiens)


name: Autophosphorylation of LTK dimer:ALKAL1,2 (Mus musculus)


name: Furin cleaves pro-factor VII to factor VII (Sus scrofa)


name: 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: PLK1 phosphorylates NEK9 (Caenorhabditis elegans)


name: Frataxin transfers Fe2+ to ACO2 (Rattus norvegicus)


name: 6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+) => 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH


name: Activated FGFR4 mutants bind PLCG1 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol = a 1,3-diacyl-sn-glycerol + a monoacyl-sn-glycero-3-phosphocholine


name: PIPOX oxidises PPCA to P6C (Xenopus tropicalis)


name: 3-(aminomethyl)indole + S-adenosyl-L-methionine = (1H-indol-3-yl)-N-methylmethanamine + H(+) + S-adenosyl-L-homocysteine


name: Digestion of branched starch (amylopectin) by extracellular amylase (Caenorhabditis elegans)


name: inosine(out) + Na(+)(out) = inosine(in) + Na(+)(in)


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Bos taurus)


name: Complement factor I binds to MCP, CR1:C4b, C3b (Gallus gallus)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Gallus gallus)


name: Polyubiquitination of substrate (Drosophila melanogaster)


name: 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH


name: (11Z,14Z)-eicosadienoate + NH4(+) => (11Z,14Z)-eicosadienamide + H2O


name: Association of procollagen type XX (Gallus gallus)


name: (2S)-2-hydroxypinocembrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (S)-pinocembrin + O2 + reduced [NADPH--hemoprotein reductase]


name: Gamma-secretase cleaves APP(672-770) to APP(672-711) and APP(672-713) (Homo sapiens)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [TM7SF2] (Bos taurus)


name: hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity


name: AH2 + prostaglandin G3 <=> A + H2O + prostaglandin H3


name: Axonal transport of NGF:Trk complexes (Rattus norvegicus)


name: Elastic fibres bind associated proteins (Bos taurus)


name: (3R)-citramalate(in) + sulfate(out) => (3R)-citramalate(out) + sulfate(in)


name: 3beta-hydroxyandrost-5-en-17-one + O2 + reduced [NADPH--hemoprotein reductase] = 3beta,7alpha-dihydroxyandrost-5-en-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate


name: (9Z,12Z)-octadecadienoate + AH2 + O2 = 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + cholesterol => cholesteryl 3-beta-D-glucoside + N-hexadecanoylsphing-4-enine


name: 2 ATP + L-proline + L-tryptophan <=> 2 AMP + brevianamide F + 2 diphosphate + 2 H(+)


name: a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA + H2O => 2-deoxy-D-ribose 5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)


name: Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE (Caenorhabditis elegans)


name: docosanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E)-docosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2-heptyl-3-hydroxy-4(1H)-quinolone + O2 = CO + H(+) + N-octanoylanthranilate


name: glycylglycyl-L-isoleucine(out) + H(+)(out) => glycylglycyl-L-isoleucine(in) + H(+)(in)


name: Formation of CSL NCOR corepressor complex (Rattus norvegicus)


name: A + all-trans-3,4-didehydro-13,14-dihydroretinol <=> AH2 + all-trans-3,4-didehydroretinol


name: Dephosphorylation of pChREBP (Ser 556) by PP2A (Homo sapiens)


name: dehydro-D-arabinono-1,4-lactone + H(+) + H2O2 => D-arabinono-1,4-lactone + O2


name: 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: ATPase-coupled inorganic anion transmembrane transporter activity


name: 17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucosiduronate + H(+) + UDP => 17alpha-estradiol 3-O-(beta-D-glucuronate) + UDP-N-acetyl-alpha-D-glucosamine


name: 7,8-dihydroxykynurenate + H(+) + NADH => 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+)


name: JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Canis familiaris)


name: an N-acylsphing-4-enine + CDP-choline = a sphingomyelin + CMP + H(+)


name: L-arginine + O2 <=> 4-guanidinobutanamide + CO2 + H2O


name: Formation of PRC2-EZH2 complex (Xenopus tropicalis)


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Canis familiaris)


name: asperlicin E + H2O + NAD(+) => asperlicin C + H(+) + NADH + O2


name: a disubstituted aliphatic (S)-hydroxynitrile <=> a ketone + hydrogen cyanide


name: Exchange of oxygen with sulfur in MoCo (Canis familiaris)


name: a (3E,5Z)-dienoyl-CoA => a (2E,4E)-(5,6-saturated)-dienoyl-CoA


name: 3-oxopropanoyl-CoA + H2O => 3-oxopropanoate + CoA + H(+)


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Canis familiaris)


name: Activated protein C cleaves factor VIIIa (Homo sapiens)


name: an acyl-CoA + L-lysyl-[protein] => CoA + H(+) + N(6)-acyl-L-lysyl-[protein]


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Drosophila melanogaster)


name: 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na(+)(out) => 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na(+)(in)


name: 1-O-alkyl-sn-glycero-3-phosphate + acetyl-CoA <=> 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA


name: LRTOMT transfers Met to DA, forming 3MT (Canis familiaris)


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Bos taurus)


name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Bos taurus)


name: H2O + N-formylmethanofuran => formate + methanofuran


name: FOXO3 translocates from the mitochondrial matrix to the nucleus (Canis familiaris)


name: 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialurate + H(+) => FMNH2 + O2


name: (S)-2-amino-6-oxohexanoate + H2O + NADP(+) => 2 H(+) + L-2-aminoadipate + NADPH


name: a medium chain fatty acid + 2 H(+) + NADH => a medium-chain fatty aldehyde + H2O + NAD(+)


name: ACSS3 ligates CoA to CH3COO- (Drosophila melanogaster)


name: alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP-alpha-D-galactofuranose <=> beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + H(+) + UDP


name: a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O = a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + sulfate


name: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) => (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH


name: 3-geranyl-4-hydroxybenzoate + diphosphate => (2E)-geranyl diphosphate + 4-hydroxybenzoate


name: Migfilin interacts with VASP (Xenopus tropicalis)


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Rattus norvegicus)


name: Formation of the PINCH-ILK-parvin complex (Caenorhabditis elegans)


name: 2,4'-dihydroxyacetophenone + O2 = 4-hydroxybenzoate + formate + 2 H(+)


name: glyoxylate + H2O + pentanoyl-CoA <=> 3-propylmalate + CoA + H(+)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Mus musculus)


name: 3,5,7-trioxododecanoyl-CoA <=> CO2 + CoA + olivetol


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Danio rerio)


name: 1-O-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + succinate


name: 3beta-hydroxy-chol-5-ene-24-oyl-CoA + A = 3beta-hydroxy-chol-5,22-dien-24-oyl-CoA + AH2


name: (S)-2-methyl-3-oxopropanoate + H2O + NAD(+) <=> 2 H(+) + methylmalonate + NADH


name: a 2'-deoxyadenosine in double-stranded DNA + CO2 + glyoxal + succinate => 2-oxoglutarate + a 1,N(6)-etheno-2'-deoxyadenosine in double-stranded DNA + H2O + O2


name: Formation of tonofilament bundles (Rattus norvegicus)


name: 5-methoxytryptamine + acetyl-CoA = CoA + H(+) + melatonin


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Gallus gallus)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Homo sapiens)


name: FBXL17 ubiquitinates BACH1 (in BACH1:FBXL17:SCF (SKP2)) (Homo sapiens)


name: 4-O-(beta-D-glucosyl)-4-(E)-coniferyl aldehyde + H(+) + UDP => (E)-coniferaldehyde + UDP-alpha-D-glucose


name: GNRHR binds chemical antagonists (Caenorhabditis elegans)


name: SDH complex dehydrogenates succinate (Caenorhabditis elegans)


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Gallus gallus)


name: 4-(hydroxylamino)-N,N-dimethylaniline + acetaldehyde => ethanol + N,N-dimethyl-4-nitrosoaniline


name: NADP(+) + propan-2-ol <=> acetone + H(+) + NADPH


name: Recruitment of XPA and release of CAK  (Drosophila melanogaster)


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Homo sapiens)


name: H2O + N-(9Z-octadecenoyl)-L-methionine <=> (9Z)-octadecenoate + L-methionine


name: Fe(III)-di(C-5-deoxy-beta-D-glucosyl)-enterobactin + H2O = Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+)


name: Activation of Rho by LARG and PDZ-RhoGEF (Bos taurus)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers in the nucleus (Canis familiaris)


name: Alkalization of the phagosomal lumen by NOX2 (Canis familiaris)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Schizosaccharomyces pombe)


name: PTK2 autophosphorylates (Caenorhabditis elegans)


name: Somatostatin receptors bind somatostatin and cortistatin (Gallus gallus)


name: mTORC1 phosphorylates AKT1S1 (Canis familiaris)


name: Activated FGFR2:p-FRS bind to PPTN11 (Rattus norvegicus)


name: 3-oxocyclopentanecarbonitrile + 2 H2O = 3-oxocyclopentanecarboxylate + NH4(+)


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Bos taurus)


name: a 3-hydroxy-fatty acyl-CoA = a (2E)-enoyl-CoA + H2O


name: (2,4-dichlorophenoxy)acetate + 2-oxoglutarate + O2 => 2,4-dichlorophenol + CO2 + glyoxylate + succinate


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Mus musculus)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Rattus norvegicus)


name: MVD decarboxylates MVA5PP to IPPP (Homo sapiens)


name: CHRM2,4 bind acetylcholine (Xenopus tropicalis)


name: L-glutamine(out) + L-serine(in) + Na(+)(out) = L-glutamine(in) + L-serine(out) + Na(+)(in)


name: Phosphorylated RHOU translocates to the endosome membrane (Schizosaccharomyces pombe)


name: RRAGC,D exchanges GTP for GDP (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Sus scrofa)


name: NLRX1 inhibits MAVS-DDX58 interaction (Bos taurus)


name: Elongation and translocation of the extended telomeric chromosome end (Gallus gallus)


name: adenosine 3',5'-bisphosphate + H(+) + sulfoglycolithocholate => 3'-phosphoadenylyl sulfate + glycolithocholate


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + CDP-choline <=> 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: SUMOylation of TDG with SUMO2,3 (Gallus gallus)


name: NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Bos taurus)


name: 3-(hydrohydroxyphosphoryl)pyruvate + CO2 => 1-carboxyvinyl carboxyphosphonate + H(+)


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Xenopus tropicalis)


name: 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + H2O + O2 => a 2'-deoxycytidine in double-stranded DNA + CO2 + glyoxal + succinate


name: TRAPPC complexes exchange GTP for GDP on RAB1 (Bos taurus)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Rattus norvegicus)


name: 3,5-dimethoxytoluene + H(+) + S-adenosyl-L-homocysteine => 3-methoxy-5-methylphenol + S-adenosyl-L-methionine


name: SLCO2B1 has a narrow substrate specificity (Drosophila melanogaster)


name: (E)-4-hydroxynon-2-enal + H(+) + NADPH => 4-hydroxynonanal + NADP(+)


name: Ubiquitinated AXIN is degraded by the proteasome (Xenopus tropicalis)


name: glyoxylate + L-leucine = 4-methyl-2-oxopentanoate + glycine


name: MITF-M-dependent DCT gene expression (Homo sapiens)


name: p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor (Xenopus tropicalis)


name: ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA (Dictyostelium discoideum)


name: acetyl-CoA + ATP + cytidine(34) in elongator tRNA(Met) + H2O <=> ADP + CoA + H(+) + N(4)-acetylcytidine(34) in elongator tRNA(Met) + phosphate


name: (S)-2-hydroxypropylphosphonate + CMP + H(+) => cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + H2O


name: 2 CO2 + reduced 2[4Fe-4S]-[ferredoxin] => oxalate + oxidized 2[4Fe-4S]-[ferredoxin]


name: SHC1 binds to the phosphorylated EGF receptor:ligand complex (Rattus norvegicus)


name: L-glutamine(in) + L-methionine(out) + Na(+)(out) => L-glutamine(out) + L-methionine(in) + Na(+)(in)


name: DENND3 exchanges GTP for GDP on RAB12 (Mus musculus)


name: Expression of Acyl-CoA Desaturase (Stearoyl CoA Desaturase, SCD) (Homo sapiens)


name: ATP + L-glutamate + tyramine <=> ADP + gamma-L-glutamyltyramine + H(+) + phosphate


name: Liganded-ALK dimer binds type I ALK-binding TKIs (Danio rerio)


name: ADP + alpha-D-ribose 1,5-bisphosphate + H(+) => alpha-D-ribose 1-phosphate + ATP


name: H(+) + N,N-dihydroxy-L-phenylalanine => (E)-phenylacetaldehyde oxime + CO2 + H2O


name: PKR inhibitors bind PKR (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Carbonic Anhydrase VI hydrates carbon dioxide to bicarbonate and a proton (Mus musculus)


name: DPP4 binds DPP4 inhibitors (Rattus norvegicus)


name: trans-Golgi Network Lysosomal Vesicle Scission (Rattus norvegicus)


name: 1,4-dihydroxy-2-naphthoate + all-trans-tridecaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-13 + CO2 + diphosphate


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + reduced [electron-transfer flavoprotein]


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+) + N(epsilon)-GMP-L-lysyl-[protein] = a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-lysyl-[protein]


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphate => a 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA


name: H(+)(out) + taurine(out) => H(+)(in) + taurine(in)


name: H(+)(out) + L-phenylalanyl-L-phenylalanine(out) <=> H(+)(in) + L-phenylalanyl-L-phenylalanine(in)


name: PEBP1 binds activated RAF1 (Plasmodium falciparum)


name: an inositol-1-phosphoceramide + H2O <=> 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + cholesterol = 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z-octadecenoate)


name: MFAP2, MFAP5 bind microfibrils (Canis familiaris)


name: Association of Ku heterodimer with ends of DNA double-strand break (Bos taurus)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CTP + H(+) => 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) + syringate <=> 3-O-methylgallate + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: an N-methyl-L-amino acid + H2O + O2 <=> an L-alpha-amino acid + formaldehyde + H2O2


name: UV-DDB ubiquitinates XPC (Canis familiaris)


name: 2 H(+) + O2 + p-cymene + 2 reduced [2Fe-2S]-[ferredoxin] = 4-isopropylbenzyl alcohol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2-methoxyestrone + UDP-alpha-D-glucuronate = 2-methoxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: Activated FGFR3:p-FRS bind to PPTN11 (Bos taurus)


name: 2-AG hydrolysis to arachidonate by MAGL (Saccharomyces cerevisiae)


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Caenorhabditis elegans)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-mannosamine <=> H(+) + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + UDP


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Xenopus tropicalis)


name: AH2 + androsta-1,4-diene-3,17-dione => A + androst-4-ene-3,17-dione


name: SOS mediated nucleotide exchange of RAS (SHC) (Gallus gallus)


name: Phosphorylation of MEF2 proteins by p38 (Danio rerio)


name: (R)-carnitine + hexadecanoyl-CoA => CoA + O-hexadecanoyl-(R)-carnitine


name: Collagen type I binds integrin alpha11beta1 (Xenopus tropicalis)


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Sus scrofa)


name: A + a 3-oxosteroid => a 3-oxo-Delta(1)-steroid + AH2


name: SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Rattus norvegicus)


name: H2O + N(6)-decanoyl-L-lysyl-[protein] + NAD(+) = 2''-O-decanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: FDPS dimer transfers IPPP to DMAPP (Canis familiaris)


name: RAC3 GDIs block activation of RAC3 (Canis familiaris)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Drosophila melanogaster)


name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Rattus norvegicus)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Sus scrofa)


name: 3',4',5-trihydroxy-3,7-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => rhamnetin + S-adenosyl-L-methionine


name: Activated PKC phosphorylates SHC1 (Rattus norvegicus)


name: GNRHR binds GNRHR peptide agonists (Homo sapiens)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Rattus norvegicus)


name: H(+) + L-arginine + NADPH + O2 = H2O + N(omega)-hydroxy-L-arginine + NADP(+)


name: Binding of ADAR1 homodimer to dsRNA duplex (Bos taurus)


name: Autophosphorylation of LTK dimer:ALKAL1,2 (Gallus gallus)


name: ALAD condenses 2 dALAs to form PBG (Mus musculus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = 19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SUMOylation of RXRA with SUMO1 (Mus musculus)


name: RHOT2 binds effectors at the mitochondrial outer membrane (Bos taurus)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Danio rerio)


name: alpha-secretase cleaves the p75NTR extracellular domain (Homo sapiens)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + O2 + reduced [flavodoxin] => a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + H(+) + H2O + oxidized [flavodoxin]


name: GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol (Bos taurus)


name: NAD(+) + octan-1-ol = H(+) + NADH + octanal


name: 15-cis-phytoene + 2 A <=> 2 AH2 + all-trans-zeta-carotene


name: Trans-autophosphorylation of ERBB4 homodimers (Mus musculus)


name: POLI incorporates dNMP opposite to damaged DNA base (Drosophila melanogaster)


name: ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE (Canis familiaris)


name: ATP + L-glutamate + spermidine <=> ADP + gamma-L-glutamylspermidine + H(+) + phosphate


name: (+)-minovincinine + acetyl-CoA = (+)-echitovenine + CoA


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 (Mus musculus)


name: CLIP3 and CYLD bind TNF signaling complex (Homo sapiens)


name: a ganglioside GM1 (d18:1(4E)) + H2O => a ganglioside GA1 (d18:1(4E)) + N-acetylneuraminate


name: I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Canis familiaris)


name: H2O + NADP(+) = ADP-D-ribose 2'-phosphate + H(+) + nicotinamide


name: Phosphorylated STATs are released (Gallus gallus)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Saccharomyces cerevisiae)


name: Nuclear DUSPs dephosphorylate MAPKs (Dictyostelium discoideum)


name: MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin (Homo sapiens)


name: Acitretin binds to RAR:RXR (Homo sapiens)


name: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + O2 + reduced [NADPH--hemoprotein reductase] = DIBOA + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,6-dihydroxyphenazine + NADPH + O2 <=> 1,6-dihydroxyphenazine N(5)-oxide + H2O + NADP(+)


name: CYP2S1 4-hydroxylates atRA (Caenorhabditis elegans)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O <=> acetate + an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative


name: CO binds to free ferrohemoglobin (Canis familiaris)


name: Tyrosine is hydroxylated to dopa (Caenorhabditis elegans)


name: GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Homo sapiens)


name: LIPs hydrolyse TG to DAG and RCOOH (Homo sapiens)


name: NLRP3 oligomerizes via NACHT domains (Homo sapiens)


name: ATP + carbamoyl phosphate + H2O <=> carbamoyl adenylate + diphosphate + phosphate


name: [(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O <=> [(1->4)-3,6-bisphospho-alpha-D-glucosyl](n) + n AMP + 2n H(+) + n phosphate


name: Dissociation of CANX from nonameric complex (Mus musculus)


name: ATP + L-aspartate + NH4(+) <=> ADP + H(+) + L-asparagine + phosphate


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 10-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-acetyl-4'-phosphopantetheine => acetyl-CoA + H2O


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: (1R,4S)-1-hydroxylimonen-2-one + H(+) + NADH => (1R,2R,4S)-limonene-1,2-diol + NAD(+)


name: 4-O-methylrhodomycin D + H2O = 10-carboxy-13-deoxydaunorubicin + H(+) + methanol


name: MSH2:MSH6 exchanges ADP for ATP (Rattus norvegicus)


name: 2 A + a carotenoid beta-end derivative = a carotenoid chi-end derivative + 2 AH2


name: Defective IDUA does not hydrolyse the unsulfated alpha-L-iduronosidic link in DS (Homo sapiens)


name: POLK incorporates dNMP opposite to damaged DNA base (Caenorhabditis elegans)


name: dihydrocurcumin + NADP(+) => curcumin + H(+) + NADPH


name: Formation of hair keratin fibres (Mus musculus)


name: [(1->4)-alpha-D-glucosyl](n) + an NDP-alpha-D-glucose = [(1->4)-alpha-D-glucosyl](n+1) + a ribonucleoside 5'-diphosphate + H(+)


name: SOS mediated nucleotide exchange of RAS (SHC) (Mus musculus)


name: Addition of the third nucleotide on the nascent transcript (Saccharomyces cerevisiae)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Xenopus tropicalis)


name: ATP + beta-alanine + dopamine = AMP + beta-alanyl-dopamine + diphosphate + H(+)


name: ISGylation of DDX58 (Plasmodium falciparum)


name: ELAC2 cleaves the 3' end of pre-tRNA (Homo sapiens)


name: precorrin-4 + S-adenosyl-L-methionine <=> precorrin-5 + S-adenosyl-L-homocysteine


name: Inner coat assembly and cargo binding (Drosophila melanogaster)


name: BTNL2 binds activated T cells surface (Homo sapiens)


name: MSK1 activates ATF1 (Drosophila melanogaster)


name: ATP binding to HSP90 triggers conformation change (Saccharomyces cerevisiae)


name: TP53 stimulates ZNF385A transcription (Homo sapiens)


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Sus scrofa)


name: Expression of IRX1 during nephron development (Homo sapiens)


name: a [peptide](in) + ADP + H(+) + phosphate => a [peptide](out) + ATP + H2O


name: JMJD6 demethylates Me2sR4-HIST1H4 (Sus scrofa)


name: 4-acetamidobutanoate + H2O = 4-aminobutanoate + acetate


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Saccharomyces cerevisiae)


name: ATP + L-aspartyl-tRNA(Asn) <=> 4-phosphooxy-L-aspartyl-tRNA(Asn) + ADP + H(+)


name: VEGFA-165 dimer binds VEGFR2 dimer (Homo sapiens)


name: CYTH proteins bind ARF1:GTP (Canis familiaris)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Xenopus tropicalis)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Mus musculus)


name: all-trans-hexaprenyl diphosphate = diphosphate + macrophomene


name: 2 a 1-acyl-sn-glycerol <=> a 1,2-diacyl-sn-glycerol + glycerol


name: 2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine => diphthine-[translation elongation factor 2] + H(+) + S-adenosyl-L-homocysteine


name: 2-phenylacetaldehyde + L-alanine => 2-phenylethylamine + pyruvate


name: factor VIII + von Willebrand factor multimer -> factor VIII:von Willibrand factor multimer (Gallus gallus)


name: 2-oxoglutarate + GDP-D-glycero-alpha-D-manno-heptose = (S)-2-hydroxyglutarate + GDP-D-glycero-4-keto-alpha-D-lyxo-heptose


name: Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)


name: C5a receptor binds C5a anaphylatoxin (Rattus norvegicus)


name: Phosphorylation of ZAP-70 by Lck (Sus scrofa)


name: POU5F1 (OCT4), SOX2, NANOG bind the GSC promoter (Homo sapiens)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Rattus norvegicus)


name: 4-hydroxy-6-(2-oxoundec-10-en-1-yl)pyran-2-one + 3 CO2 + 4 CoA => 9-decenoyl-CoA + 3 H(+) + 3 malonyl-CoA


name: Binding of SHC1 to insulin receptor (Gallus gallus)


name: 3beta-hydroxy-chol-5-ene-24-oyl-CoA + A => 3beta-hydroxy-chol-5,22-dien-24-oyl-CoA + AH2


name: 3-oxosphinganine + dodecanoyl-CoA = CoA + H(+) + N-dodecanoyl-3-oxosphinganine


name: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-apiose <=> 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + H(+) + UDP


name: Formation of ORC(2-5) complex (Canis familiaris)


name: ESTG binds ESR2:chaperone complex (Mus musculus)


name: [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity


name: sphing-4-enine 1-phosphate(in) <=> sphing-4-enine 1-phosphate(out)


name: 19-hydroxy-11-deoxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 19-oxo-11-deoxycorticosterone + 2 H2O + 2 oxidized [adrenodoxin]


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 => 1-O-methyl-(13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Xenopus tropicalis)


name: Peroxisomal ACOT4,6,8 hydrolyse MCFA-CoA, LCFA-CoA (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: GDP + H(+) + methyl 8-{[beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate => GDP-beta-L-fucose + methyl-8-{[beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: Coumarin is 7-hydroxylated by CYP2A13 (Sus scrofa)


name: (R)-normetanephrine + H(+) + S-adenosyl-L-homocysteine => (R)-noradrenaline + S-adenosyl-L-methionine


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Homo sapiens)


name: Active ALK phosphorylates IRS1 (Bos taurus)


name: 2'-O-methylguanosine(2270) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine => guanosine(2270) in 21S rRNA + S-adenosyl-L-methionine


name: 2-oxoglutarate + decanoyl-CoA + O2 = 2-hydroxydecanoyl-CoA + CO2 + succinate


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Mus musculus)


name: 15-methylhexadecasphing-4-enine 1-phosphate + H2O <=> 15-methylhexadecasphing-4-enine + phosphate


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Rattus norvegicus)


name: A1 and A3 receptors bind adenosine (Mus musculus)


name: Defective SI does not hydrolyze Suc (Homo sapiens)


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Canis familiaris)


name: D-maltoheptaonate + H(+) => D-maltoheptaono-1,5-lactone + H2O


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Sus scrofa)


name: 3-hydroxybenzoyl-CoA + 2 H(+) + 3 malonyl-CoA <=> 2,3',4,6-tetrahydroxybenzophenone + 3 CO2 + 4 CoA


name: SARS-CoV-2 E pentamer transports Ca2+  (Homo sapiens)


name: 3-aminopropanal + H2O2 + NH4(+) => H2O + O2 + propane-1,3-diamine


name: ATM phosphorylates DYRK2 (Gallus gallus)


name: PEX7 binds cargo proteins containing PTS2 (Mus musculus)


name: 2-oxoglutarate + 5-dehydro-6-demethoxyfumagillol + O2 <=> 5-dehydro-6-demethoxy-6-hydroxyfumagillol + CO2 + succinate


name: Binding of IRS to insulin receptor (Gallus gallus)


name: Interaction of DAP12 and CLM7 (Mus musculus)


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O <=> 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: PI3K binds to EGF:EGFR:GRB2:GAB1 (Xenopus tropicalis)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine => 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA


name: Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity (Homo sapiens)


name: (+)-thujan-3-ol + NADP(+) => (+)-thujan-3-one + H(+) + NADPH


name: NUAK1 phosphorylates TP53 (Rattus norvegicus)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Rattus norvegicus)


name: RUNX1 binds FOXP3 (Caenorhabditis elegans)


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Danio rerio)


name: (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: a 3'-hydroxyflavone + S-adenosyl-L-methionine <=> a 3'-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: 2-oxoglutarate + [2-(trimethylamino)ethyl]phosphonate + O2 = [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + CO2 + succinate


name: 1-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O <=> (9Z,12Z)-octadecadienoate + glycerol + H(+)


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Homo sapiens)


name: Interleukin-3 receptor alpha subunit binds Interleukin-3 (Bos taurus)


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Sus scrofa)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Rattus norvegicus)


name: ATP + D-lysine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate => ADP + H(+) + N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine + phosphate


name: ethanolamine + N-dodecanoyl-heptadecasphing-4-enine-1,3-cyclic phosphate => N-dodecanoyl-heptadecasphing-4-enine-1-phosphoethanolamine


name: H2O + N-octanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-octanoyl ethanolamine


name: Association of procollagen type XII (Sus scrofa)


name: [fructose-bisphosphate aldolase]-N(6),N(6),N(6)-trimethyl-L-lysine + 3 H(+) + 3 S-adenosyl-L-homocysteine => [fructose-bisphosphate aldolase]-L-lysine + 3 S-adenosyl-L-methionine


name: 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + H2O <=> beta-D-Gal-(1<->1')-Cer + H(+) + sulfate


name: L-glutaminyl-[protein] + L-lysyl-[protein] = [protein]-L-lysyl-N(6)-5-L-glutamyl-[protein] + NH4(+)


name: 5-dehydroepisterol + 2 H2O + NADP(+) = ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2


name: Formation of hydroxyallysine by LOX (Bos taurus)


name: 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine = [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: phosphocreatine + H2O => creatinine + orthophosphate (Homo sapiens)


name: 2-hydroxyethylphosphonate + O2 = H(+) + hydrogencarbonate + methylphosphonate


name: beta-alanyl-L-ornithine + H2O = beta-alanine + L-ornithine


name: SL (surrogate light chain) binds IgH to form pre-BCR (Homo sapiens)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Bos taurus)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Homo sapiens)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Mus musculus)


name: misfolded CFTR is degraded by the 26S proteasome (Rattus norvegicus)


name: 2-methylpropanal + H(+) + NADPH + NH4(+) => 2-methylpropan-1-amine + H2O + NADP(+)


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Xenopus tropicalis)


name: Auto-ubiquitination of TRAF6 (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate => (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: 2-oxoglutarate(in) + prostaglandin F2alpha(out) => 2-oxoglutarate(out) + prostaglandin F2alpha(in)


name: Interaction of cadherin with Beta/gamma catenin, alpha catenin and p120 catenin (Bos taurus)


name: SeMet is converted to AdoSeMet by MAT (Danio rerio)


name: Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes (Danio rerio)


name: 2-naphthol + 3'-phosphoadenylyl sulfate => 2-naphthyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 3beta-hydroxy-5alpha-androstan-17-one + O2 + reduced [NADPH--hemoprotein reductase] => 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ryanodine-sensitive calcium-release channel activity


name: RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Homo sapiens)


name: L-serine + NAD(+) <=> aminoacetaldehyde + CO2 + NADH


name: Caspase-mediated cleavage of Acinus (Caenorhabditis elegans)


name: Binding of ATP to P2X receptors (Bos taurus)


name: 2-oxoglutarate + L-lysyl-[protein] + O2 = (5S)-5-hydroxy-L-lysyl-[protein] + CO2 + succinate


name: TORC2 (mTOR) phosphorylates AKT at S473 (Saccharomyces cerevisiae)


name: carnosine(out) + n H(+)(out) = carnosine(in) + n H(+)(in)


name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] (Sus scrofa)


name: Activation of ATP sensitive Potassium channels in muscle cells (Gallus gallus)


name: (3R)-3-hydroxy-8'-apo-beta-carotenal + O2 => (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + (3R)-all-trans-3-hydroxyretinal


name: dGTP + glyoxal <=> N(2)-(1-hydroxy-2-oxoethyl)-dGTP


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Mus musculus)


name: AH2 + chloroethene => A + chloride + ethene + H(+)


name: an N-acetyl-alpha-D-glucosaminyl derivative + UDP-alpha-D-galactose => a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl derivative + H(+) + UDP


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Canis familiaris)


name: an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP-alpha-D-glucose <=> an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside + H(+) + UDP


name: ATP + guanidinoacetate => ADP + H(+) + phosphoguanidinoacetate


name: H2O + N-hexadecanoylsphing-4-enine => hexadecanoate + sphing-4-enine


name: glutathione(in) + taurocholate(out) => glutathione(out) + taurocholate(in)


name: Tumstatin binds integrin alphaVbeta 3, alpha3beta1 (Homo sapiens)


name: ALD3A1 oxidises 4HPCP to CXPA (Drosophila melanogaster)


name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Xenopus tropicalis)


name: Basolateral transport of Cipro to extracellular space (Homo sapiens)


name: indolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] <=> 3-hydroxyindolin-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RRAGA,B exchanges GDP for GTP (Drosophila melanogaster)


name: WLS:WNT complex is internalized for maturation into exosomes (Mus musculus)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Caenorhabditis elegans)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Rattus norvegicus)


name: SLC6A18 transports Gly from extracellular region to cytosol (Danio rerio)


name: RAC1 GDIs block activation of RAC1 (Dictyostelium discoideum)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Rattus norvegicus)


name: 30-hydroxy-11-oxo-beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = glycyrrhetaldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PLK1 phosphorylates FIRRM at S43 (Danio rerio)


name: Loss of Rrn3 from RNA Polymerase I promoter escape complex (Sus scrofa)


name: 4-O-([2-N-acetyl-alpha-D-glucosaminyl-1-D-ribitylphospho](n)-di{[2R]-1-glycerylphospho})-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP => 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-N-acetyl-alpha-D-glucosamine


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate <=> plasmodiophorol B


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Drosophila melanogaster)


name: IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Canis familiaris)


name: D-mannitol 1-phosphate + H2O <=> D-mannitol + phosphate


name: 2-acyl LPE is acylated to PE by LPEAT (Canis familiaris)


name: H2O + N(2)-benzoyl-D-arginine-4-nitroanilide => 4-nitroaniline + H(+) + N(2)-benzoyl-D-arginine


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Saccharomyces cerevisiae)


name: a guaiacol + H(+) + S-adenosyl-L-homocysteine => a catechol + S-adenosyl-L-methionine


name: The PACAP receptor binds PACAP (Danio rerio)


name: a 1,2-diacylglycerol + H2O <=> a 2-acylglycerol + a carboxylate + H(+)


name: Caspase-mediated cleavage of Lamin A (Sus scrofa)


name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (2E,6E)-farnesol + diphosphate


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Mus musculus)


name: nascent polypeptide-associated complex binding


name: BESTs transport cytosolic Cl- to extracellular region (Homo sapiens)


name: (2E)-octenal + H(+) + pyruvate = (S)-3-acetyloctanal + CO2


name: (6E)-8-oxogeraniol + NAD(+) => (6E)-8-oxogeranial + H(+) + NADH


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Rattus norvegicus)


name: Initial activation of proMMP2 by MMP14 (Sus scrofa)


name: ALDH3B2 oxidises HXAL to PALM (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A hexaacyl 1-(2-aminoethyl diphosphate) <=> a 1,2-diacyl-sn-glycerol + lipid A 1,4'-bis(2-aminoethyl diphosphate)


name: dihydroxyacetone phosphate + hexadecanoyl-CoA = 1-hexadecanoylglycerone 3-phosphate + CoA


name: Beta-catenin binds SOX proteins (Rattus norvegicus)


name: Recruitment and activation of N-WASP by Cdc42 (Bos taurus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Gallus gallus)


name: chorismate = 3-hydroxybenzoate + pyruvate


name: 2 H(+) + NADPH + 2 O2 + protodeoxyviolaceinate <=> CO2 + 2 H2O + NADP(+) + proviolacein


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Drosophila melanogaster)


name: The COG complex binds RABs at the Golgi membrane (Dictyostelium discoideum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphoethanolamine


name: Integrin alphaVbeta3 binds p-6Y-VEGFR2 (Danio rerio)


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Drosophila melanogaster)


name: [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate => [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)


name: LIN7, CASK and APBA1 bind (Mus musculus)


name: SRD5A1 dehydrogenates TEST to DHTEST (Sus scrofa)


name: 2 N(omega)-hydroxy-L-arginine + 2 O2 + reduced [flavodoxin] = 3 H(+) + 2 H2O + 2 L-citrulline + 2 nitric oxide + oxidized [flavodoxin]


name: NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 (Drosophila melanogaster)


name: (9Z)-octadecen-1-ol + (9Z)-octadecenoyl-CoA = 1-O-(9Z)-octadecenyl (9Z)-octadecenoate + CoA


name: GTP-dependent polynucleotide 5'-hydroxyl-kinase activity


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)


name: Association of RAD51 with RAD52:DNA double-strand break ends (Mus musculus)


name: RUNX1 binds the SWI/SNF complex (Homo sapiens)


name: G alpha (12) binds BTK (Rattus norvegicus)


name: (2R,3S,11R)-acetylaszonalenin + CoA => (2R,3S,11R)-aszonalenin + acetyl-CoA


name: diphosphate + isopimara-8(14),15-diene => (+)-copalyl diphosphate


name: (9Z)-octadecenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphate => 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: Release of noradrenaline  at the synapse (Sus scrofa)


name: H(+) + UDP + vitexin 2''-O-beta-D-glucoside => UDP-alpha-D-glucose + vitexin


name: CRK binds BCAR1 and or PXN (Rattus norvegicus)


name: a fatty acid + S-adenosyl-L-methionine = a fatty acid methyl ester + S-adenosyl-L-homocysteine


name: H2O + L-arginine + NAD(+) <=> 5-guanidino-2-oxopentanoate + H(+) + NADH + NH4(+)


name: 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine + AH2 <=> 2-(prostaglandin H2)-sn-glycero-3-phosphoethanolamine + A + H2O


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Bos taurus)


name: K63polyUb-IRAK1 dissociates (Caenorhabditis elegans)


name: ZFPM proteins bind GATA proteins (Xenopus tropicalis)


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP => (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP-alpha-D-glucuronate


name: SIRT4 transfers ADPRib to GLUD (Mus musculus)


name: L-histidine + S-adenosyl-L-methionine => (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: phylloquinone monooxygenase (2,3-epoxidizing) activity


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: Alpha-1-Microglobulin is cleaved (Homo sapiens)


name: (S)-2-amino-6-oxohexanoate + H2O + NADP(+) <=> 2 H(+) + L-2-aminoadipate + NADPH


name: 4 H(+) + uroporphyrinogen I => 4 CO2 + coproporphyrinogen I


name: Interaction of Bnip-2 with Cdc42 (Homo sapiens)


name: MAOB:FAD oxidatively deaminates TYR (Dictyostelium discoideum)


name: acetylglucosamine-inositol is deacetylated by Mca (Mycobacterium tuberculosis)


name: Oxoeicosanoid receptor can bind oxoeicosanoid (Danio rerio)


name: (6Z,9Z,12Z)-octadecatrienoate + O2 <=> 10-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate


name: Beta-catenin migrates to the nucleus (Bos taurus)


name: sitosterol + UDP-alpha-D-glucose <=> H(+) + sitosteryl 3-beta-D-glucoside + UDP


name: (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+) => (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + H(+) + NADPH


name: 17alpha-hydroxywithaferin A + UDP-alpha-D-glucose <=> 17alpha-sitoindoside IX + H(+) + UDP


name: activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Xenopus tropicalis)


name: KALRN exchanges GTP for GDP on RAC1, activating it (Caenorhabditis elegans)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Bos taurus)


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Sus scrofa)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Homo sapiens)


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Drosophila melanogaster)


name: Fibrillin-1 degradation by ELANE (Homo sapiens)


name: a uridine in rRNA + S-adenosyl-L-methionine = a 2'-O-methyluridine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Mus musculus)


name: 2-oxoglutarate + dodecanoyl-CoA + H2O = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+)


name: ADP + D-methionine(in) + H(+) + phosphate => ATP + D-methionine(out) + H2O


name: transmembrane monodehydroascorbate reductase activity


name: L-ascorbate(in) + monodehydro-L-ascorbate radical(out) = L-ascorbate(out) + monodehydro-L-ascorbate radical(in)


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Drosophila melanogaster)


name: Ubiquitinated TP53 translocates to the cytosol (Homo sapiens)


name: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol <=> D-glucose + indole-3-acetyl-1D-myo-inositol


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(4)-[histone H3] + O2 => CO2 + formaldehyde + L-lysyl(4)-[histone H3] + succinate


name: CUL3:RBX1 ubiquitinates KEAP1 (Dictyostelium discoideum)


name: Phosphorylation of YAP by LATS1 (Mus musculus)


name: ALDHs oxidise atRAL to atRA (Homo sapiens)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Canis familiaris)


name: Caspase-mediated cleavage of alpha adducin (Mus musculus)


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Homo sapiens)


name: 4-phospho-D-erythronate + NAD(+) <=> (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + H(+) + NADH


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Mus musculus)


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Canis familiaris)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)


name: prephenate dehydrogenase (NAD+) activity


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Plasmodium falciparum)


name: NCAM1 cis-homophilic interaction (Homo sapiens)


name: a long-chain fatty acyl-CoA + alpha,alpha-trehalose <=> 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + CoA


name: GAPDH tetramers reduce 1,3BPG to GA3P (Mus musculus)


name: 4-hydroxyphenylacetate + H(+) + NADPH + O2 = H2O + homogentisate + NADP(+)


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Homo sapiens)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Mus musculus)


name: TCR binds self-lipid-based antigen via CD1 (Sus scrofa)


name: 2-oxohexanoate + L-kynurenine => H2O + kynurenate + L-2-aminohexanoate


name: OCT2 mediates tubular uptake of organic cations in the kidney (Caenorhabditis elegans)


name: IL24 binds to IL22RA1:JAK1:IL20RB (Sus scrofa)


name: estrone 3-sulfate(in) + H(+)(out) <=> estrone 3-sulfate(out) + H(+)(in)


name: KSRP binds AU-rich element in 3' UTR of mRNA (Mus musculus)


name: (R)-piperazine-2-carboxamide + H2O => (R)-piperazine-2-carboxylate + NH4(+)


name: Activated FMNL3 binds G-actin (Mus musculus)


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Sus scrofa)


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine


name: genistein + UDP-alpha-D-glucose <=> genistein 7-O-beta-D-glucoside + H(+) + UDP


name: 1-(1Z-octadecenyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine <=> 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: (2R,3S)-homoisocitrate + NAD(+) => 2-oxoadipate + CO2 + NADH


name: homospermidine synthase (spermidine-specific) activity


name: NUMB:ITCH ubiquitinates GLI1 (Xenopus tropicalis)


name: SALL4 recruits NuRD to PTEN gene (Homo sapiens)


name: phosphate + presqualene alcohol => H2O + presqualene phosphate


name: USP9X binds Ub:PEX5L (Drosophila melanogaster)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Bos taurus)


name: MVD decarboxylates MVA5PP to IPPP (Dictyostelium discoideum)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Mus musculus)


name: Dimerization of LIMK1 by Hsp90 (Homo sapiens)


name: 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-octadecyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: ETA is phosphorylated to PETA by CHK/ETNK (Plasmodium falciparum)


name: Hexameric LMAN1:MCFD2 bind glycosylated Factor V and VIII precursors (Mus musculus)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Rattus norvegicus)


name: cortisol + H(+) + NADPH = 20beta-dihydrocortisol + NADP(+)


name: 2-hydroxylamino-4,6-dinitrotoluene + UDP-alpha-D-glucose = 2-hydroxylamino-4,6-dinitrotoluene-O-beta-D-glucoside + H(+) + UDP


name: Formation of collagen fibres (Sus scrofa)


name: atROL binds RBP1 (parenchymal cell) (Gallus gallus)


name: LC3:ATG7 dimer binds ATG3 (Caenorhabditis elegans)


name: perivine + S-adenosyl-L-methionine = 2 H(+) + S-adenosyl-L-homocysteine + vobasine


name: TP53 in complex with EP300, PRMT1 and CARM1 stimulates GADD45A transcription (Homo sapiens)


name: AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Rattus norvegicus)


name: DELE1(143-515) is released into the cytosol (Xenopus tropicalis)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Mus musculus)


name: genistein 7-O-beta-D-glucoside + H2O <=> beta-D-glucose + genistein


name: ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA


name: beta-D-glucosylceramide + UDP-alpha-D-galactose => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H(+) + UDP


name: DNMT3A binds Me2sR4-HIST1H4 (Mus musculus)


name: RUNX1 binds PRC1 complexes (Rattus norvegicus)


name: D-ribose 5-phosphate + guanine => GMP + H2O


name: Profilin:G-actin binds MKL1 (Mus musculus)


name: Thrombin-activated PARs activate Gq (Canis familiaris)


name: a ubiquinone + formate + H(+) => a ubiquinol + CO2


name: RCC1 stimulates GDP to GTP exchange on RAN (Schizosaccharomyces pombe)


name: 13-dihydrocarminomycin + H(+) + NADPH + O2 => carminomycin + 2 H2O + NADP(+)


name: Histone H3.3 deposition at telomere (Bos taurus)


name: single-strand selective uracil DNA N-glycosylase activity


name: Cleavage of uracil by SMUG1 glycosylase (Homo sapiens)


name: (2'-deoxyribonucleoside 5'-methylphosphotriester)-DNA + L-cysteinyl-[protein] = 2'-deoxyribonucleotide-DNA + H(+) + S-methyl-L-cysteinyl-[protein]


name: AH2 + ATP + 2 Co(II)-[dimethylamine-specific corrinoid protein] + H2O <=> A + ADP + 2 Co(I)-[dimethylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + H(+) + S-adenosyl-L-homocysteine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine


name: p62 recruits an atypical PKC (Rattus norvegicus)


name: CYP11B2 18-hydroxylates CORST to 18HCORST (Rattus norvegicus)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Homo sapiens)


name: L-arginine(out) + N(omega)-methyl-L-arginine(in) <=> L-arginine(in) + N(omega)-methyl-L-arginine(out)


name: USP34 deubiquitinates AXIN1,AXIN2 (Bos taurus)


name: 6-hydroxycyclohex-1-ene-1-carbonyl-CoA + NAD(+) <=> 6-oxocyclohex-1-ene-1-carbonyl-CoA + H(+) + NADH


name: benzoyl-CoA + H(+) + NADPH + O2 => 3-hydroxybenzoyl-CoA + H2O + NADP(+)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO4 (Rattus norvegicus)


name: Phosphorylation of MEF2 proteins by p38 (Dictyostelium discoideum)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Bos taurus)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Drosophila melanogaster)


name: L-alanine(in) + L-threonine(out) => L-alanine(out) + L-threonine(in)


name: PRDM9 binds recombination hotspot motifs in DNA (Homo sapiens)


name: a ganglioside Ac-O-8-GT3(d18:1(4E)) => a ganglioside Ac-O-9-GT3 (d18:1(4E))


name: CO2 + UDP-alpha-D-xylose => H(+) + UDP-alpha-D-glucuronate


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Danio rerio)


name: Activation of proMMP9 by proteases (Rattus norvegicus)


name: p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Caenorhabditis elegans)


name: H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Bos taurus)


name: H2O + N(omega)-methyl-L-arginine => L-citrulline + methylamine


name: 3-sulfinopropanoyl-CoA + H2O = H(+) + propanoyl-CoA + sulfite


name: gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling


name: Expression of glutathione S-transferase alpha 2 (Homo sapiens)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O = 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine


name: H(+) + S-adenosyl-L-homocysteine + ubiquinol-8 => 3-demethylubiquinol-8 + S-adenosyl-L-methionine


name: (2E,6E)-farnesyl diphosphate <=> (+)-epi-isozizaene + diphosphate


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)


name: a C28-steroid + O2 + reduced [NADPH--hemoprotein reductase] => a (22S)-22-hydroxy C28-steroid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Plasmodium falciparum)


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Saccharomyces cerevisiae)


name: N-tetradecanoyl-(2S)-hydroxyglycine <=> glyoxylate + tetradecamide


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Homo sapiens)


name: Association of NS1 (1C) with Cul5 and SCF (Homo sapiens)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Dictyostelium discoideum)


name: chorismate + H2O <=> (3R,4R)-3,4-dihydroxy-3,4-dihydrobenzoate + pyruvate


name: a flavanone + O2 + reduced [NADPH--hemoprotein reductase] <=> a 2-hydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AH2 + cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + A + cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Canis familiaris)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + CoA => an acyl-CoA + sn-glycero-3-phosphoethanolamine


name: PTK2/SRC-1 phosphorylates BCAR1 (Homo sapiens)


name: 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoA => (E)-4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA


name: A + cyclo(L-arginyl-(Z)-dehydro-3,4-dihydroxytyrosyl) + H2O => AH2 + cyclo(L-arginyl-L-dehydrotyrosyl) + O2


name: 2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate


name: 2-oxoglutarate + O2 + preaustinoid A2 = CO2 + H2O + preaustinoid A3 + succinate


name: Caspase 3-mediated cleavage of PKC delta (Bos taurus)


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Saccharomyces cerevisiae)


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Caenorhabditis elegans)


name: Association of procollagen type X (Caenorhabditis elegans)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: Activated FGFR2 binds PLCG1 (Drosophila melanogaster)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Sus scrofa)


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Canis familiaris)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Drosophila melanogaster)


name: (2E)-hexadecenoyl-CoA + FADH2 => FAD + H(+) + hexadecanoyl-CoA


name: (4R)-limonene + H(+) + NADPH + O2 = H2O + limonene 1,2-epoxide + NADP(+)


name: ARRB bind GPCRs (Caenorhabditis elegans)


name: p-S215 FOXO3 translocates to the nucleus (Gallus gallus)


name: NR1H2,3 binds the PLIN1 gene (Homo sapiens)


name: Calpain2 (m-Calpain, CAPN2:CAPNS:Ca2+) cleaves VCL (Vinculin) (Mus musculus)


name: 2 H(+) + H2O + N-hydroxy-L-isoleucine + oxidized [NADPH--hemoprotein reductase] => L-isoleucine + O2 + reduced [NADPH--hemoprotein reductase]


name: a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose => an alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)


name: GRB2:SOS1 binds to HBEGF:p-Y-EGFR (Mus musculus)


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Rattus norvegicus)


name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA (Mus musculus)


name: (2R)-3-phospho-glyceroyl phosphate + [phosphate](n) = (2R)-3-phosphoglycerate + [phosphate](n+1)


name: 4-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O


name: MCCC mutants don't synthesize beta-methylglutaconyl-CoA (Homo sapiens)


name: Relaxin receptor 2 binds relaxin 2 and INSL3 (Canis familiaris)


name: a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => a 1-[(6Z,9Z,12Z,15Z)-octadectetraenoyl]-2-acyl-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: DCC interaction with ROBO1 (Homo sapiens)


name: (5E)-tetradecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,5E)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: TREM,CD300 binds lipids (Rattus norvegicus)


name: H2O + N(6)-methyl-dATP <=> diphosphate + H(+) + N(6)-methyl-dAMP


name: Fusion and Release of SARS-CoV-2 Nucleocapsid (Homo sapiens)


name: D-fucose(in) + H(+)(in) = D-fucose(out) + H(+)(out)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Sus scrofa)


name: Fibronectin degradation by ADAM8 (Mus musculus)


name: NADP(+) + prephenate => 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH


name: botC HC:LC binds GT1b on the target cell surface (Homo sapiens)


name: KDM5A-D demethylate Me2K5-histone H3 (Rattus norvegicus)


name: Beclin-1 complex phosphorylates PtdIns (Bos taurus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L  methylate methyl-lysine-37 of histone H3 (H3K36) (Rattus norvegicus)


name: SUMOylation of NFKBIA with SUMO1 (Gallus gallus)


name: 2-propylphenol + H(+) + NADH + O2 <=> 3-propylcatechol + H2O + NAD(+)


name: adenylyl MoO2(OH)-molybdopterin cofactor + H2O = AMP + 2 H(+) + Mo-molybdopterin


name: RGGT binds the RAB-binding subunit (Danio rerio)


name: depalmitoylated eNOS translocates from plasma membrane (Bos taurus)


name: 12-phosphooxy-(9Z)-octadecenoate + H2O = 12-hydroxy-(9Z)-octadecenoate + phosphate


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Mus musculus)


name: Recruitment of POLB to oxidatively damaged AP site (Mus musculus)


name: Collagen types VI, IX bind integrin alpha10beta1 (Canis familiaris)


name: Caspase 3-mediated cleavage of PKC delta (Drosophila melanogaster)


name: Translocation of peptide bound MHC class I complex to cell surface (Mus musculus)


name: PTK6 phosphorylates KHDRBS1 (Homo sapiens)


name: benzoyl-AMP + CoA = AMP + benzoyl-CoA + H(+)


name: 2-methylhexadecanoate + ATP + CoA => 2-methylhexadecanoyl-CoA + AMP + diphosphate


name: Uncoating of clathrin-coated vesicles and fusion with endosomes (Canis familiaris)


name: D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+) <=> diphosphate + GDP-D-glycero-alpha-D-manno-heptose


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Drosophila melanogaster)