name: 4-O-[(D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n UDP-alpha-D-glucose <=> 4-O-[(2-beta-D-glucosyl-D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n H(+) + n UDP


name: RAS GEFs promote RAS nucleotide exchange (Mus musculus)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] <=> 18-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: AKT-phosphorylated FOXO3 translocates to cytosol (Canis familiaris)


name: CIDEA:CIDEC binds lipid droplets (Mus musculus)


name: Transphosphorylation of JAK1 (Bos taurus)


name: (4S)-4-hydroxy-L-arginine => H2O + L-enduracididine


name: Inactivation of APC/C via CDC20 sequestration (Gallus gallus)


name: D-methionine + H2O + O2 => 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+)


name: dichlorochromopyrrolate + H(+) + 2 H2O + NH4(+) => 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2


name: Interleukin-1 receptor type 2 binds Interleukin 1 (Xenopus tropicalis)


name: glycocholate + L-arginine = glycine + L-arginocholate


name: 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe-4S]-[ferredoxin] => 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]-[ferredoxin] + 2 phosphate


name: OPN (osteopontin) degradation by MMP3, MMP7 (Danio rerio)


name: PYCRL decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Homo sapiens)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate = (1S,4R)-camphene + diphosphate


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Sus scrofa)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)


name: alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP => di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Bos taurus)


name: (6R)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) <=> (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)


name: T-type VDCC bind T-type VDCC blockers (Bos taurus)


name: H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + n Na(+)(in) = CO2 + N(6)-biotinyl-L-lysyl-[protein] + n Na(+)(out)


name: (9Z)-octadecenoyl-CoA + 1-heptadecanoyl-sn-glycero-3-phosphate => 1-heptadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: P-selectin binds P-selectin ligand (Danio rerio)


name: Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation (Homo sapiens)


name: itaconate + L-cysteinyl-[protein] => S-(2,3-dicarboxypropyl)-L-cysteinyl-[protein]


name: (2S)-ethylmalonyl-CoA + NADP(+) <=> (2E)-butenoyl-CoA + CO2 + NADPH


name: TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 (Rattus norvegicus)


name: USP21 deubiquitinates RIPK1,DDX58 (Homo sapiens)


name: Release of Cytochrome c from mitochondria (Sus scrofa)


name: [thioredoxin]-disulfide + dGDP + H2O <=> [thioredoxin]-dithiol + GDP


name: DCPS scavenges the 7-methylguanosine cap of mRNA (Homo sapiens)


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Xenopus tropicalis)


name: 2-demethylmenaquinone-8 + H(+) + NADH => 2-demethylmenaquinol-8 + NAD(+)


name: GNLY binds the bacterial cell surface in the phagosome (Danio rerio)


name: thioredoxin, oxidized + NADPH + H+ => thioredoxin, reduced + NADP+ (Bos taurus)


name: EGF-TM7 receptors bind chondroitin sulphate (Mus musculus)


name: GRB2-1:SOS1 binds p-Y427-SHC1 (Drosophila melanogaster)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Bos taurus)


name: MAOA:FAD oxidatively deaminates of 5HT (Rattus norvegicus)


name: H2O + S-methyl-5'-thioadenosine <=> 5-(methylsulfanyl)-D-ribose + adenine


name: Arachidonate is oxidised to 15S-HpETE by ALOX15/15B (Canis familiaris)


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Danio rerio)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Saccharomyces cerevisiae)


name: WLS:WNT complex is internalized for maturation into exosomes (Rattus norvegicus)


name: Recruitment of SOS to plasma membrane (Homo sapiens)


name: (S)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH => (1S,2S)-pseudoephedrine + NAD(+)


name: AMP + H(+) + hexadecanoyl-[(hydroxy)phthioceranic acid synthase] => hexadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase]


name: hexadecan-1-ol + hexadecanoyl-CoA = CoA + hexadecanyl hexadecanoate


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Danio rerio)


name: a long-chain (3R)-hydroxyacyl-CoA = a long-chain (2E)-enoyl-CoA + H2O


name: a 5'-end NAD(+)-phospho-ribonucleoside in snoRNA + H2O = a 5'-end phospho-ribonucleoside in snoRNA + H(+) + NAD(+)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Mus musculus)


name: RHOD binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: phosphate + RNA(n+1) => a ribonucleoside 5'-diphosphate + RNA(n)


name: RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Mus musculus)


name: H2O + N-methyl-L-alanine + NADP(+) = H(+) + methylamine + NADPH + pyruvate


name: Expression of Interferon-alpha and beta mediated by VAF/pIRF7:CBP/p300 (Homo sapiens)


name: glyoxylate + NH4(+) + urea => (S)-2-ureidoglycine + H2O


name: NICD1 in complex with RBPJ (CSL) recruits MAML (Gallus gallus)


name: ATP + H(+)(in) + H2O + K(+)(out) <=> ADP + 2 H(+)(out) + K(+)(in) + phosphate


name: 2-dehydro-3-deoxy-D-gluconate(in) + H(+)(in) = 2-dehydro-3-deoxy-D-gluconate(out) + H(+)(out)


name: GPI-bound CD14 binds LPS (Canis familiaris)


name: (2E)-2-methylpropenoyl-CoA + reduced [electron-transfer flavoprotein] => 2-methylpropanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: Masitinib-resistant KIT mutants do not bind masitinib (Homo sapiens)


name: CARMA1 recruits MALT1 and BCL10 forming CBM Complex (Rattus norvegicus)


name: ABCA3 transports PC, PG from ER membrane to lamellar body (Caenorhabditis elegans)


name: Initial activation of proMMP1 (Bos taurus)


name: HIPK2 phosphorylates RUNX1 (Mus musculus)


name: phosphate + urate D-ribonucleoside => alpha-D-ribose 1-phosphate + urate


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Mus musculus)


name: dGMP + H2O <=> 2-deoxy-D-ribose 5-phosphate + guanine


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Homo sapiens)


name: a hydroperoxy polyunsaturated fatty acid + 2 glutathione => a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2O


name: beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine + H(+) + UDP => N-acetyl-D-glucosamine + UDP-alpha-D-galactose


name: P2Y5 receptor can bind to LPA (Danio rerio)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Mus musculus)


name: a cholesterol ester(out) => a cholesterol ester(in)


name: HPDL dioxygenates HPPA (Dictyostelium discoideum)


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Mus musculus)


name: PolyUb-misfolded proteins bind VCP:HDAC6:HSP90:HSF1 (Homo sapiens)


name: Cleavage of DFF45 (224) by caspase-3 (Gallus gallus)


name: uridine(32) in tRNA => pseudouridine(32) in tRNA


name: a 1,2-diacylglycerol + a glycerophospholipid = a 1-acyl-sn-glycero-3-phospholipid + a triacylglycerol


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Canis familiaris)


name: Association of procollagen type XXII (Caenorhabditis elegans)


name: Release of acetylcholine at the synapse (Caenorhabditis elegans)


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)


name: CYP11A1 cleaves 20a,22b-DHCHOL (Mus musculus)


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 5-methylorsellinate + O2 + reduced [NADPH--hemoprotein reductase]


name: cholate(out) + n H(+)(out) = cholate(in) + n H(+)(in)


name: (R)-glycerate + 2 H(+) + NADH => D-glyceraldehyde + H2O + NAD(+)


name: SLC36A4 transports extracellular L-Pro to the cytosol (Canis familiaris)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPC (Homo sapiens)


name: n ATP + n D-ornithine + H2O = n AMP + n diphosphate + n H(+) + N(5)-(D-ornithyl)-[N(5)-(D-ornithyl)]n-1


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Schizosaccharomyces pombe)


name: (E)-3-aminocoumarate + ATP + H(+) + nitrite => (E)-3-diazocoumarate + AMP + diphosphate + H2O


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Rattus norvegicus)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: 4-methyl-3-oxohexanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxy-4-methylhexanoyl-[ACP] + NADP(+)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Rattus norvegicus)


name: uridine(516) in 16S rRNA = pseudouridine(516) in 16S rRNA


name: Some HSPGs are secreted to the plasma membrane (Drosophila melanogaster)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP-alpha-D-mannose = (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + GDP + H(+)


name: TCF7L1/TCF7L2/LEF1:CTNNB1 promote transcription of the MYC gene (Homo sapiens)


name: 15,17(3)-seco-F430-17(3)-acid + 3 A + ADP + phosphate => 3 AH2 + ATP + H2O + Ni-sirohydrochlorin a,c-diamide


name: Activated FGFR2 phosphorylates SHC1 (Mus musculus)


name: a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose 6-phosphate + H(+) => a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Caenorhabditis elegans)


name: PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex (Dictyostelium discoideum)


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + ATP + CoA => 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: PSMG1:PSMG2 dimer binds the 20S core particle outer ring (Homo sapiens)


name: (+)-copalyl diphosphate + H2O <=> diphosphate + manool


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a 2-acyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: TGFBR3 translocation to plasma membrane (Danio rerio)


name: 1-O-alkyl-sn-glycerol + ATP => 1-O-alkyl-sn-glycero-3-phosphate + ADP + H(+)


name: DHCR24 reduces LAN to 24,25-dhLAN (Caenorhabditis elegans)


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Mus musculus)


name: (S)-glaucine + S-adenosyl-L-methionine = (S)-N-methylglaucine + H(+) + S-adenosyl-L-homocysteine


name: IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Canis familiaris)


name: ajmaline + S-adenosyl-L-methionine = 4-methylajmaline + H(+) + S-adenosyl-L-homocysteine


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Drosophila melanogaster)


name: Dephosphorylation of JAK1 by SHP1 (Bos taurus)


name: norspermine + S-adenosyl 3-(methylsulfanyl)propylamine = caldopentamine + 2 H(+) + S-methyl-5'-thioadenosine


name: heptan-1-ol + NADP(+) = H(+) + heptanal + NADPH


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Drosophila melanogaster)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Xenopus tropicalis)


name: MAP1LC3B binds KEAP1 and SQSTM1 (Mus musculus)


name: RAC1 GEFs activate RAC1 (Rattus norvegicus)


name: H2O + L,L-cystathionine => 2-oxobutanoate + L-cysteine + NH4(+)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK5 (Mus musculus)


name: H2O + N-formyl-L-kynurenine => formate + H(+) + L-kynurenine


name: (R)-2-hydroxy-3-methylbutyrate + NADP(+) <=> 3-methyl-2-oxobutanoate + H(+) + NADPH


name: C4b binds to target cell surface (Gallus gallus)


name: (2E)-geranyl diphosphate + H2O = (S)-alpha-terpineol + diphosphate


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Bos taurus)


name: Activation of Ca-permeable Kainate receptors (Canis familiaris)


name: Interleukin-5 receptor alpha subunit binds Interleukin-5 (Bos taurus)


name: 2 (S)-lactate(in) + prostaglandin D2(out) <=> 2 (S)-lactate(out) + prostaglandin D2(in)


name: Dissociation of p-Y427-SHC1 from insulin receptor (Sus scrofa)


name: a 2-oxocarboxylate + H(+) + NADPH => a (2S)-2-hydroxycarboxylate + NADP(+)


name: an N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O <=> 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + O2


name: 2 H(+) + NADH + pentanoate => H2O + NAD(+) + pentanal


name: Expression of Adiponectin (Homo sapiens)


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O => 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + tetradecanoate


name: (R)-noradrenaline + S-adenosyl-L-methionine <=> (R)-normetanephrine + H(+) + S-adenosyl-L-homocysteine


name: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H(+) + NADH => 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)


name: Laminins:Nidogens binds HSPG2 (Homo sapiens)


name: A1 and A3 receptors bind adenosine (Sus scrofa)


name: 1-nonadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: ASC binds Caspase-8 complex (Canis familiaris)


name: aldosterone hemiacetal + UDP-alpha-D-glucuronate = aldosterone hemiacetal 18-beta-glucuronide + H(+) + UDP


name: ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in) = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Xenopus tropicalis)


name: MTMR4 binds phosphorylated SMAD2/3 (Sus scrofa)


name: (R)-2-hydroxyglutarate + NADP(+) = 2-oxoglutarate + H(+) + NADPH


name: (E)-caffeoyl-CoA + AMP + H(+) => (E)-caffeoyl-AMP + CoA


name: ethyl hexadecanoate + H2O = ethanol + H(+) + hexadecanoate


name: GDIs block activation of RHOA (Canis familiaris)


name: ABCB1 transports xenobiotics out of the cell (Canis familiaris)


name: RLBP1 binds atROL to form RLBP1:atROL (Dictyostelium discoideum)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Gallus gallus)


name: Factor Xa inhibitors bind Va:Xa (Gallus gallus)


name: 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+) => bis(2-ethylhexyl)phthalate + H2O


name: H2O + L-homocysteine + oxidized 2[4Fe-4S]-[ferredoxin] => 3 H(+) + hydrogen sulfide + L-aspartate 4-semialdehyde + reduced 2[4Fe-4S]-[ferredoxin]


name: MBTPS2 (S2P) cleaves CREB3L3 (Homo sapiens)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Sus scrofa)


name: 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA + S-adenosyl-L-methionine = 5'-deoxyadenosine + archaeosine(15) in tRNA + 2 H(+) + L-1-piperideine-6-carboxylate + L-methionine


name: (S)-2-hydroxyglutarate + O2 => 2-oxoglutarate + H2O2


name: 2 H(+) + sulfite + thiocyanate => hydrogen cyanide + thiosulfate


name: Autocatalytic activation of proMMP2 (Canis familiaris)


name: FA anion diffuses laterally to UCP (Rattus norvegicus)


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Mus musculus)


name: ADP + alpha-D-glucose 1-phosphate + H(+) = ADP-alpha-D-glucose + phosphate


name: IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Homo sapiens)


name: Microtubule-independent trafficking of connexons to the plasma membrane (Bos taurus)


name: 2-oxoglutarate + 2 H(+) + L-glutamine + 2 reduced [2Fe-2S]-[ferredoxin] => 2 L-glutamate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: dimethylamine + formaldehyde => H(+) + trimethylamine N-oxide


name: dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] <=> CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: CRH gene expression is repressed by MECP2 (Homo sapiens)


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Mus musculus)


name: (2E)-hexenoyl-CoA + FADH2 => FAD + H(+) + hexanoyl-CoA


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Mus musculus)


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Canis familiaris)


name: P2Y10 receptor can bind to LPA (Mus musculus)


name: MTRR reduces cob(II)alamin to meCbl (Homo sapiens)


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Homo sapiens)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Sus scrofa)


name: (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + O2 + reduced [NADPH--hemoprotein reductase] = glyceollin I + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + S-acylglutathione = a carboxylate + glutathione + H(+)


name: POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 (Xenopus tropicalis)


name: chylomicron remnant + apoE => chylomicron remnant:apoE complex (Homo sapiens)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Mus musculus)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Gallus gallus)


name: Activated MAPKs phosphorylate MAP2K1 (Drosophila melanogaster)


name: DLD dimer dehydrogenates dihydrolipoyl (Plasmodium falciparum)


name: 2,6-dimethylheptanoyl-CoA + H2O = 2,6-dimethylheptanoate + CoA + H(+)


name: Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: p-S256-Aquaporin-2 passively transports water into cell (Danio rerio)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + methanol


name: beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => all-trans-beta-carotene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: p-S MAPK6,4 phosphorylate MAPKAPK5 (Danio rerio)


name: mTORC1 phosphorylates AKT1S1 (Dictyostelium discoideum)


name: alpha-D-ribose 1-methylphosphonate 5-triphosphate + H2O <=> alpha-D-ribose 1-methylphosphonate 5-phosphate + diphosphate + H(+)


name: HIF-alpha translocates from cytosol to nucleus (Homo sapiens)


name: Corticosteroids bind to CBG in blood (Homo sapiens)


name: Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Homo sapiens)


name: dCDP(out) + UTP(in) <=> dCDP(in) + UTP(out)


name: ATM binds PEX5 (Drosophila melanogaster)


name: H2O + 2 NAD(+) + tetracenomycin C => 2 H(+) + 2 NADH + 2 O2 + tetracenomycin A2


name: SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Bos taurus)


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Homo sapiens)


name: 2-dehydro-3-deoxy-D-arabinonate + NAD(+) = 5-hydroxy-2,4-dioxopentanoate + H(+) + NADH


name: trans-Golgi Network Coat Activation (Sus scrofa)


name: (2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Plasmodium falciparum)


name: 3alpha-hydroxy-5beta-androstan-17-one + NAD(+) => 5beta-androstane-3,17-dione + H(+) + NADH


name: a 1-acyl-sn-glycero-3-phosphocholine + CoA => an acyl-CoA + sn-glycerol 3-phosphocholine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Gallus gallus)


name: pS181-S-Farn-Me KRAS4B translocates to the outer mitochondrial membrane (Homo sapiens)


name: Dimerization of procollagen type VI (Caenorhabditis elegans)


name: MLNR (GPR38) is a receptor for motilin (Sus scrofa)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 = 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Homo sapiens)


name: MAPKs phosphorylate ETS1 and ETS2 (Rattus norvegicus)


name: 3-(2,3-dihydroxyphenyl)propanoate + O2 = (2Z,4E)-2-hydroxy-6-oxonona-2,4-dienedioate + H(+)


name: Autocatalytic activation of MMP3 (Caenorhabditis elegans)


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Mus musculus)


name: DENND3 exchanges GTP for GDP on RAB12 (Canis familiaris)


name: [protein]-disulfide + H(+) + NADH => [protein]-dithiol + NAD(+)


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Bos taurus)


name: Li(+)(in) + melibiose(in) => Li(+)(out) + melibiose(out)


name: Formation of COPII vesicle (Homo sapiens)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Gallus gallus)


name: ME1 tetramer decarboxylates OA to PYR (Sus scrofa)


name: (S)-2-benzylsuccinate + succinyl-CoA = (S)-2-benzylsuccinyl-CoA + succinate


name: Syk activation leads to SLP-76 activation (Xenopus tropicalis)


name: (9S,10S)-10-hydroxy-9-(phosphooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Bos taurus)


name: DDR2 binds collagen type I, II, III, V, X fibrils (Caenorhabditis elegans)


name: Cdc45 associates with the pre-replicative complex at the origin (Dictyostelium discoideum)


name: a myo-inositol phosphate + H2O => myo-inositol + phosphate


name: (3R)-hydroxy-(23Z,26Z,29Z,32Z,35Z)-octatriacontapentaenoyl-CoA <=> (2E,23Z,26Z,29Z,32Z,35Z)-octatriacontahexaenoyl-CoA + H2O


name: acetyl-CoA + hydrogen sulfide <=> CoA + thioacetate


name: D-glucose + sphing-4-enine => beta-D-glucosyl-(1<->1)-sphing-4-enine + H2O


name: (2S)-naringenin 7-O-beta-D-glucoside + H2O = (2S)-naringenin + beta-D-glucose


name: SNX9 recruits components of the actin polymerizing machinery (Canis familiaris)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)


name: B3GALT4 transfers Gal to gangliosides (Bos taurus)


name: Collagen type VII binds integrin alpha2beta1 (Rattus norvegicus)


name: [eIF5A protein]-N-(4-aminobutylidene)-L-lysine + H(+) + NADH <=> [eIF5A protein]-deoxyhypusine + NAD(+)


name: a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate


name: CoA + O-(2E)-butenoyl-(R)-carnitine => (2E)-butenoyl-CoA + (R)-carnitine


name: MTMR14, MTMR3 dephosphorylate PI3P (Gallus gallus)


name: factor V -> factor Va + factor V activation peptide (Homo sapiens)


name: SLC35D1 hexamer transports UDP-GlcA, UDP-GlcNAc from cytosol to endoplasmic reticulum lumen (Rattus norvegicus)


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Canis familiaris)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Canis familiaris)


name: 2 Fe(III)-[cytochrome c] + H2O + sulfite = 2 Fe(II)-[cytochrome c] + 2 H(+) + sulfate


name: 2-methylbutanal + H(+) + NADPH + NH4(+) => 2-methylbutanamine + H2O + NADP(+)


name: 5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Homo sapiens)


name: all-trans retinoic acid 4-hydrolase activity


name: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] = all-trans-(4S)-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-hydroxybenzoate + all-trans-heptaprenyl diphosphate <=> 4-hydroxy-3-all-trans-heptaprenylbenzoate + diphosphate


name: NCOA2(869-1464) binds KAT6A(1-1118) (Sus scrofa)


name: (2E)-geranyl diphosphate <=> beta-pinene + diphosphate


name: Formation of eIF2:GDP:eIF2B intermediate (Sus scrofa)


name: Furin cleaves pro-factor X to factor X (Canis familiaris)


name: 1-(11Z-eicosenoyl)-glycerol + H2O = (11Z)-eicosenoate + glycerol + H(+)


name: beta-D-glucose + N-hexadecanoylsphing-4-enine => beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O


name: 2',3'-cyclophospho-CMP + H2O = cytidine 2'-phosphate + H(+)


name: SPRED dimer binds NF1 (Dictyostelium discoideum)


name: p-T68-CHEK2 autophosphorylates (Rattus norvegicus)


name: TNFSF9 binds TNFRSF9 (Rattus norvegicus)


name: dTDP-beta-L-evernosamine + NADPH + O2 = dTDP-N-hydroxy-beta-L-evernosamine + H2O + NADP(+)


name: RRM2 gene expression is stimulated by E2F1 and inhibited by E2F6 (Homo sapiens)


name: Endonucleolytic RISC hydrolyzes target RNAs (Homo sapiens)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Canis familiaris)


name: 27-hydroxysterol binds ESR1, ESR2 (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol <=> 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA


name: PIAS1,4 SUMOylates BRCA1 with SUMO2,3 (Sus scrofa)


name: H(+)(out) + L-methionyl-L-phenylalanyl-L-methionine(out) <=> H(+)(in) + L-methionyl-L-phenylalanyl-L-methionine(in)


name: 2-[(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex (Rattus norvegicus)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Dictyostelium discoideum)


name: Phosphorylated SHC1 recruits SHIP (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + H(+) + phosphate => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O


name: ZFPM proteins bind GATA proteins (Canis familiaris)


name: H(+) + menaquinone-7 + NADH = menaquinol-7 + NAD(+)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: SREBP1A,1C,2 translocates to the nucleus (Mus musculus)


name: p-PKR dimer phosphorylates DHX9 (Rattus norvegicus)


name: an N-acylethanolamine + H2O => a fatty acid + ethanolamine


name: Activated JNKs phosphorylate c-JUN (Homo sapiens)


name: Recruitment of Dna2 endonuclease (Caenorhabditis elegans)


name: GPVI binds Fyn and Lyn (Xenopus tropicalis)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: translation release factor activity, codon nonspecific


name: L-glutamine + scyllo-inosose <=> 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate


name: an N-acyleicosasphing-4-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O => an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)


name: TFAP2C translocates to the nucleus (Sus scrofa)


name: Interaction of other adapter proteins with p-KIT (Homo sapiens)


name: RRAGC,D hydrolyzes GTP (Caenorhabditis elegans)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,2-ditetradecanoyl-sn-glycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1,2-ditetradecanoyl-sn-glycero-3-phosphocholine


name: a 2-all-trans-polyprenylphenol + H(+) + NADPH + O2 = a 3-(all-trans-polyprenyl)benzene-1,2-diol + H2O + NADP(+)


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Homo sapiens)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Homo sapiens)


name: INTL1 binds bacterial glycans (Danio rerio)


name: GSK3 phosphorylates nucleoprotein (Homo sapiens)


name: PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Mus musculus)


name: H2O + L,L-cystathionine <=> 2-oxobutanoate + L-cysteine + NH4(+)


name: [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA => [(2->6)-alpha-D-glucosyl-(1->4)-N,7-O-diacetyl-alpha-D-neuraminosyl](n) + n CoA


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Bos taurus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) <=> 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: ERBB2 T733I does not bind tesevatinib (Homo sapiens)


name: p-T774-PKN1 phosphorylates PPP1R14A (Homo sapiens)


name: (2E)-butenoyl-CoA + L-lysyl-[protein] => CoA + H(+) + N(6)-(2E)-butenoyl-L-lysyl-[protein]


name: Activated protein C cleaves factor Va to factor Vi intermediate form (Sus scrofa)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Plasmodium falciparum)


name: 2,4-dibromophenol + CO2 + 2 H2O + NADP(+) => 3-bromo-4-hydroxybenzoate + bromide + 3 H(+) + NADPH + O2


name: PLK1 phosphorylates NUDC (Canis familiaris)


name: Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Canis familiaris)


name: LCN2:2,5DHBA binds Fe3+ (Rattus norvegicus)


name: choline(in) + n H(+)(out) => choline(out) + n H(+)(in)


name: H2O + sinigrin = (Z)-N-(sulfonatooxy)prop-2-enimidothioate + D-glucose + H(+)


name: (2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Rattus norvegicus)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + glycerol => 2 1-(9Z-octadecenoyl)-glycerol


name: gypsogenin + UDP-alpha-D-glucose = gypsogenin 28-beta-D-glucoside + UDP


name: Release of novel PDGFs as latent factors (Bos taurus)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Bos taurus)


name: NT5C2 tetramer phosphorylates RBV (Caenorhabditis elegans)


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Rattus norvegicus)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Sus scrofa)


name: CCND3,(CCND1,CCND2) binds RUNX1 (Bos taurus)


name: ADP-riboxanated L-argininyl-[protein] + H(+) + NH4(+) + nicotinamide => L-arginyl-[protein] + NAD(+)


name: Formation of the preholoproteasome (Danio rerio)


name: Alkalization of the phagosomal lumen by NOX2 (Mus musculus)


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Mus musculus)


name: PDE12 cleaves 2'-5' oligoadenylates  (Mus musculus)


name: a (3R)-3-isocyanyl-fatty acyl-[ACP] + AMP + H(+) => a (3R)-3-isocyanyl-fatty acyl-AMP + holo-[ACP]


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Rattus norvegicus)


name: myricetin + UDP-beta-L-rhamnose = H(+) + myricetin 3-O-alpha-L-rhamnoside + UDP


name: (R)-mandelonitrile + UDP-alpha-D-glucose = (R)-prunasin + H(+) + UDP


name: RCC1 stimulates GDP to GTP exchange on RAN (Caenorhabditis elegans)


name: C20 sphinganine + NADP(+) => 3-oxoeicosasphinganine + H(+) + NADPH


name: dUTP + H2O => dUMP + pyrophosphate (Saccharomyces cerevisiae)


name: a globoside NOR1 (d18:1(4E)) + H(+) + UDP => a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose


name: 13-hydroxydocosanoate + UDP-alpha-D-glucose <=> 13-(beta-D-glucosyloxy)docosanoate + H(+) + UDP


name: (2R)-3-phospho-glyceroyl phosphate + 2-deoxy-alpha-D-ribose 1-phosphate => (2R)-3-phosphoglycerate + 2-deoxy-alpha-D-ribose 1,5-bisphosphate + H(+)


name: ITPA hydrolyses ITP to IMP (Rattus norvegicus)


name: H(+)(in) + indole(in) = H(+)(out) + indole(out)


name: adenylyl MoO3-molybdopterin cofactor = adenylyl MoO2(OH)-molybdopterin cofactor


name: Dimerization of p-S133-CREB1 (Homo sapiens)


name: 3-hydroxypropionate dehydrogenase (NAD+) activity


name: Translocation of PKC theta to plasma membrane (Mus musculus)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(3,4,5,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)


name: PLA1A hydrolyses PS to 2-acyl LPS (Sus scrofa)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Saccharomyces cerevisiae)


name: Auto-ubiquitination of TRAF3 (Sus scrofa)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-43) (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-O-hexadecyl-2-acetyl-sn-glycerol = 1-O-hexadecyl-2-acetyl-3-(9Z)-octadecenoyl-sn-glycerol + CoA


name: a ganglioside GQ1c (d18:1(4E)) + H2O <=> a ganglioside GT1c (d18:1(4E)) + N-acetylneuraminate


name: glycine(out) + H(+)(in) + Na(+)(out) = glycine(in) + H(+)(out) + Na(+)(in)


name: (2E,17Z,20Z,23Z,26Z)-dotriacontapentaenoyl-CoA + H2O => (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA


name: 2xTPK1:Mg2+ phosphorylates THMN (Drosophila melanogaster)


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Drosophila melanogaster)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Homo sapiens)


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Canis familiaris)


name: ATP + GTP => diphosphate + pppA(2'-5')pG


name: a ganglioside GD1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1balpha  (d18:1(4E)) + CMP + H(+)


name: MTMR12 binds MTM1 (Caenorhabditis elegans)


name: Receptor FFAR3 binds carboxylates (Mus musculus)


name: SLC29A1 transports RBV from cytosol to extracellular region (Sus scrofa)


name: Autophosphorylation of insulin receptor (Canis familiaris)


name: Release of mature NEDD8 (Saccharomyces cerevisiae)


name: TNFSF11 binds TNFRSF11A, B (Homo sapiens)


name: (ethanolamineP) mannose (a1-2) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI -> (ethanolamineP) mannose (a1-2) (ethanolamineP) mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI (Saccharomyces cerevisiae)


name: hexadecanoyl-CoA + phytol = CoA + hexadecanoate phytyl ester


name: 5-hydroxydodecanoate + H(+) <=> delta-dodecalactone + H2O


name: H2O + N-octadecanoyl ethanolamine <=> ethanolamine + octadecanoate


name: Somatostatin receptors bind somatostatin and cortistatin (Rattus norvegicus)


name: AMP + 2 H(+) + N(5)-phospho-L-glutamine + phosphate => ATP + H2O + L-glutamine


name: Intermediate II binds CYC1, UQCRC1, UQCRC2, UQCRH (Homo sapiens)


name: a 2'-deoxyribonucleoside 3'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate


name: CUL3:RBX1 ubiquitinates KEAP1 (Rattus norvegicus)


name: S-adenosyl-L-methionine + uridine(54) in tRNA => 5-methyluridine(54) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate => [L-4-(L-arginin-2-N-yl)aspartate](n) + H2O


name: STING ubiquitination by TRIM32 or TRIM56 (Danio rerio)


name: NADPH transfers electrons to FDXR (Mus musculus)


name: 4-nitro-6-oxohepta-2,4-dienedioate <=> 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite


name: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH


name: (E)-isoeugenol + S-adenosyl-L-methionine => (E)-isomethyleugenol + H(+) + S-adenosyl-L-homocysteine


name: PAO:FAD oxidises NASPM to PTCN (Drosophila melanogaster)


name: a bacteriochlorophyllide d + H2O + S-adenosyl-L-methionine => 5'-deoxyadenosine + a 7(1)-hydroxybacteriochlorophyllide d + H(+) + L-methionine


name: Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Gallus gallus)


name: PP2A binds CTLA4 dimer (Canis familiaris)


name: Activation of p38 MAPK (Drosophila melanogaster)


name: (2R)-3-phosphoglycerate + glycolate + H(+) => 3-oxoisoapionate 4-phosphate + H2O


name: (9Z)-octadecenoyl-CoA + 1-tetradecanoyl-sn-glycero-3-phosphoethanolamine = 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: Activin A,AB,B binds Activin Receptor ACVR2A,B:ACVR1B (Mus musculus)


name: Syndecans 1, 2 & 4 bind VTN (Xenopus tropicalis)


name: SUMOylation of PML with SUMO3 (Homo sapiens)


name: 6-deoxy-6-sulfo-D-gluconate <=> 2-dehydro-3,6-dideoxy-6-sulfo-D-gluconate + H2O


name: Gi activation by P2Y purinoceptor 12 (Canis familiaris)


name: (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate = 4-methylsulfanylbutyl isothionate + H(+) + sulfate


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Mus musculus)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Saccharomyces cerevisiae)


name: H2O + N-dodecanoylsphing-4-enine => dodecanoate + sphing-4-enine


name: ATP + glycine + L-glutamyl-[protein] => ADP + glycyl-L-glutamyl-[protein] + H(+) + phosphate


name: 2-amino-4,6-dinitrotoluene + UDP-alpha-D-glucose <=> 2-amino-4,6-dinitrotoluene beta-D-glucoside + H(+) + UDP


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Canis familiaris)


name: ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Sus scrofa)


name: H2O + N-(octanoyl)-sphing-4-enine-1-phosphate <=> N-octanoylsphing-4-enine + phosphate


name: PDGFR mutants bind type II TKIs (Homo sapiens)


name: USP10,USP24,USP42 deubiquitinate TP53 (Mus musculus)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Drosophila melanogaster)


name: 1-(9Z-octadecenoyl)-2-O-(5Z,8Z,11Z,14Z-eicosatetraenyl)-sn-glycerol + H2O = (9Z)-octadecenoate + 2-O-(5Z,8Z,11Z,14Z)-eicosatetraenylglycerol + H(+)


name: "With a quinone or similar compound as acceptor"


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Homo sapiens)


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + 9-oxononanoate + H(+)


name: L-asparaginyl-[protein] + NAD(+) = H(+) + N(4)-(ADP-D-ribosyl)-L-asparaginyl-[protein] + nicotinamide


name: acetylsalicylate + L-seryl-[protein] = O-acetyl-L-seryl-[protein] + salicylate


name: HSD11B2 dehydrogenates PREDL to PREDN (Rattus norvegicus)


name: CAMK4 autophosphorylates (Drosophila melanogaster)


name: SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Canis familiaris)


name: Translocation of peptide bound MHC class I complex to cell surface (Canis familiaris)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Gallus gallus)


name: campestanol + O2 + reduced [NADPH--hemoprotein reductase] <=> 6-deoxycathasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Bos taurus)


name: phosphate(in) + sn-glycerol 3-phosphate(out) => phosphate(out) + sn-glycerol 3-phosphate(in)


name: SHC1-2 bound to MET recruits GRB2:SOS1 (Rattus norvegicus)


name: FPR is a receptor for formyl peptides (Xenopus tropicalis)


name: RNF168 binds DNA DSBs (Rattus norvegicus)


name: a tetracycline + H(+) + NADPH + O2 <=> an 11a-hydroxytetracycline + H2O + NADP(+)


name: CRHR1,CRHR2-1 binds CRH,UCN (Canis familiaris)


name: RB1 binds condensin II (Dictyostelium discoideum)


name: DOME:HOP complex forms a dimer at the plasma membrane (Drosophila melanogaster)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Sus scrofa)


name: ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Sus scrofa)


name: PSMD11 binds PSMD7:PSMD12:PSMD13:PSMD14 (Caenorhabditis elegans)


name: 3,4,17-trihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMN + H(+) + H2O => 3,17-dihydroxy-9,10-secoandrost-1,3,5(10)-triene-9-one + FMNH2 + O2


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Caenorhabditis elegans)


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Sus scrofa)


name: CBL-mediated ubiquitination of CIN85 (Sus scrofa)


name: dodecanoyl-CoA + hexadecan-1-ol <=> CoA + hexadecanyl dodecanoate


name: TGFBR3 translocation to plasma membrane (Sus scrofa)


name: carminomycin + S-adenosyl-L-methionine <=> daunorubicin + H(+) + S-adenosyl-L-homocysteine


name: (2E,9E)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein] => (9E)-octadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Sus scrofa)


name: Release of SEPT4 from mitochondria (Canis familiaris)


name: Activated FGFR3:pFRS binds GRB2:SOS1 (Danio rerio)


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)


name: CBL ubiquitinates FRS2 and FGFR2 (Rattus norvegicus)


name: Active FLT3 binds to SLA2 (Mus musculus)


name: Membrane-anchored TNF-α binds TNFR1 (Sus scrofa)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose => 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: ZNRF3 autoubiquitinates to promote its internalization (Sus scrofa)


name: ergosterol + NADP(+) => ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+) + NADPH


name: H(+) + NADPH + NH4(+) + oxaloacetate => H2O + L-aspartate + NADP(+)


name: RAC1 and CDC42 activate PAK3 (Caenorhabditis elegans)


name: GDIs block activation of RHOC (Bos taurus)


name: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = 7-O-methylvitexin 2''-O-beta-L-rhamnoside + H(+) + S-adenosyl-L-homocysteine


name: UDP-alpha-D-glucuronate(out) + UDP-alpha-D-xylose(in) = UDP-alpha-D-glucuronate(in) + UDP-alpha-D-xylose(out)


name: Formation of p-STAT1 homodimer (Homo sapiens)


name: ATP + L-seryl-[isocitrate dehydrogenase] => ADP + H(+) + O-phospho-L-seryl-[isocitrate dehydrogenase]


name: 2 flaviolin + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 3,8'-biflaviolin + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine => H2O + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + UMP => (6S)-5,6,7,8-tetrahydrofolate + 5-methyl-UMP + NADP(+)


name: HEXB cleaves the terminal GalNAc from DS (Bos taurus)


name: 2-hydroxyphytanoyl-CoA <=> 2,6,10,14-tetramethylpentadecanal + formyl-CoA


name: (2S)-naringenin + 2-oxoglutarate + O2 = (2R,3R)-dihydrokaempferol + CO2 + succinate


name: 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Bos taurus)


name: H(+)(out) + thymidine(out) => H(+)(in) + thymidine(in)


name: PTGS2 dimer oxidises EPA to PGH3 (Xenopus tropicalis)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + octanoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-octanoyl-sn-glycerol + CoA


name: p75NTR interacts with RIP2 (Rattus norvegicus)


name: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H2O + NAD(+) => H(+) + L-2-aminopentanoate + NADH + pyruvate


name: PITPNM1,2,3 exchange PI for PA (Rattus norvegicus)


name: 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)


name: SIRT4 transfers ADPRib to GLUD (Homo sapiens)


name: an N-acetyl-alpha-neuraminosyl-(2->8)-N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP + H(+) => a ganglioside GM4 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: H(+) + L-rhamnono-1,4-lactone + NADH => L-rhamnofuranose + NAD(+)


name: keto-D-fructose 6-phosphate + phosphate <=> acetyl phosphate + D-erythrose 4-phosphate + H2O


name: cGMP stimulates Protein Kinase G (Homo sapiens)


name: DDX5 binds ESR1:estrogen:TFF1 gene promoter (Homo sapiens)


name: USP13 deubiquitinates BECN1,USP10 (Mus musculus)


name: Translocation of Cyclin A:Cdk2 complexes to the nucleus (Homo sapiens)


name: PEX5S,L binds cargo proteins containing PTS1 (Homo sapiens)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Mus musculus)


name: galactarate(out) + H(+)(out) => galactarate(in) + H(+)(in)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (24R)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PGH2 diffuses from the endoplasmic reticulum lumen to the cytosol (Homo sapiens)


name: (E)-caffeoyl-CoA + H2O = 3-hydroxy-3-(3,4-dihydroxyphenyl)propanoyl-CoA


name: Phosphorylation of cPLA2 by MAPK p38 alpha (Gallus gallus)


name: (3R)-hydroxy-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA => (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + H2O


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: 3'-demethylstaurosporine + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + staurosporine


name: Activation of RAC1 by VAV (Rattus norvegicus)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Mus musculus)


name: Mis18 complex binds the centromere (Xenopus tropicalis)


name: phytol + tetradecanoyl-CoA => CoA + tetradecanoate phytyl ester


name: Phosphorylated KHDRBS1 translocates to the cytosol (Rattus norvegicus)


name: cyclohexane-1-carboxylate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + trans-4-hydroxycyclohexane-1-carboxylate


name: Interaction of PECAM-1 and SHP-1 (Canis familiaris)


name: glycyl-L-glutamate + H2O <=> glycine + L-glutamate


name: 2 CoA + NADP(+) => CoA-disulfide + H(+) + NADPH


name: TNF-mediated dimerization of procaspase-8 (Homo sapiens)


name: IL23R in IL23:IL23 receptor complex is phosphorylated (Homo sapiens)


name: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine => phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine


name: Caspase mediated cleavage of alpha-II-Fodrin (Canis familiaris)


name: chloride(out) + hypotaurine(out) + 2 Na(+)(out) = chloride(in) + hypotaurine(in) + 2 Na(+)(in)


name: FAHD1 dimer hydrolyses OA to PYR (Danio rerio)


name: 3-oxohexadecanoyl-CoA + H(+) + NADPH <=> (3R)-hydroxyhexadecanoyl-CoA + NADP(+)


name: PLK2 phosphorylates CENPJ (Canis familiaris)


name: The ABCC family mediates organic anion transport (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate + H2O = beta-eudesmol + diphosphate


name: 1-cyclohexylethanamine + H2O + NADP(+) <=> 1-cyclohexylethanone + H(+) + NADPH + NH4(+)


name: ATP + glutathione + glutathionylspermidine => ADP + H(+) + phosphate + trypanothione


name: 3-oxo-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + NADP(+)


name: Internalization of receptor bound antigen into clathrin coted vesicles (Rattus norvegicus)


name: H2O + kynuramine + O2 => 3-(2-aminophenyl)-3-oxopropanal + H2O2 + NH4(+)


name: Initiation of vRNA Synthesis (Homo sapiens)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an acyl-CoA <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + CoA


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Drosophila melanogaster)


name: fatty acid transmembrane transporter activity


name: (Z)-biformene + diphosphate => ent-copalyl diphosphate


name: ent-kaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] => ent-7alpha-hydroxykaur-16-en-19-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Caenorhabditis elegans)


name: L-threo-tetrahydrobiopterin + 2 NADP(+) <=> 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH


name: H2O + salicin-6-phosphate <=> beta-D-glucose 6-phosphate + salicyl alcohol


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Sus scrofa)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O = (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Saccharomyces cerevisiae)


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: 2-methyl-cis-aconitate + H2O => 2-methylcitrate


name: acetaldehyde + FMN + 2 H(+) + H2O + nitrite => ethylnitronate + FMNH2 + O2


name: FGFR2IIIa TM binds ligand and full length receptors to inhibit signaling (Homo sapiens)


name: (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + O2 <=> (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole-[protein] + H2O2


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Homo sapiens)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Gallus gallus)


name: JAK2 phosphorylation of GHR (Gallus gallus)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Rattus norvegicus)


name: D-glucose + sitosterol => H2O + sitosteryl 3-beta-D-glucoside


name: RHOG translocates to the ER membrane (Mus musculus)


name: H(+) + NADH + pyruvate => (R)-lactate + NAD(+)


name: a 1,4-lactone + H2O = a 4-hydroxyacid + H(+)


name: an N-acyl-sphingoid base + CDP-ethanolamine => an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H(+)


name: 4-O-methylxanthohumol + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + xanthohumol


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA <=> (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O


name: AAC1 imports a proton (Canis familiaris)


name: 4-aminobutanoate + urea => 4-guanidinobutanoate + H2O


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Homo sapiens)


name: GDP + methylglyoxal = N(2)-(1-hydroxy-2-oxopropyl)-GDP


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Canis familiaris)


name: A1 and A3 receptors bind adenosine (Bos taurus)


name: Fusion of vesicle containing the HA trimer, NA tetramer and M2 tetramer to the Golgi apparatus (Homo sapiens)


name: SUMOylation of TFAP2C with SUMO1 (Danio rerio)


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Danio rerio)


name: (3R)-hydroxynonanoyl-[ACP] + NADP(+) => 3-oxononanoyl-[ACP] + H(+) + NADPH


name: RAC1,RAC2,RHOG activate PI3K (Sus scrofa)


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexanoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Drosophila melanogaster)


name: Hemopexin binds Hemes (Drosophila melanogaster)


name: (E)-cinnamyl acetate + CoA => (E)-cinnamyl alcohol + acetyl-CoA


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O = beta-D-glucosylceramide + D-galactose


name: group III metabotropic glutamate receptor activity


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Drosophila melanogaster)


name: 5-methylcytosine + H(+) + H2O => NH4(+) + thymine


name: 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: Release of mature NEDD8 (Rattus norvegicus)


name: Spontaneous hydrolysis of C3 thioester (Homo sapiens)


name: butanoyl-CoA + L-seryl-[protein] <=> CoA + O-butanoyl-L-seryl-[protein]


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Drosophila melanogaster)


name: all-trans-retinyl hexadecanoate + H2O = all-trans-retinol + H(+) + hexadecanoate


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Mus musculus)


name: 2 Na(+)(out) + nicotinate(out) = 2 Na(+)(in) + nicotinate(in)


name: Dephosphorylation of Lck-pY505 by CD45 (Bos taurus)


name: H(+) + prop-2-ynal + pyrroloquinoline quinol => prop-2-yn-1-ol + pyrroloquinoline quinone


name: PLA2G2A binds bacterial phospholipids (Gallus gallus)


name: presqualene diphosphate <=> 15-cis-4,4'-diapophytoene + diphosphate


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Sus scrofa)


name: UROD decarboxylates URO1 to COPRO1 (Drosophila melanogaster)


name: 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + H2O => (9Z)-octadecenoate + 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Rattus norvegicus)


name: Benzene is hydroxylated to phenol (Dictyostelium discoideum)


name: dCMP + H(+) + UDP => 2'-deoxycytidine + UTP


name: adenosine 3',5'-bisphosphate + 2 H(+) + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-4'-phosphopantetheine => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O


name: (R)-carnitine + H(+) + NADPH + O2 <=> (3R)-3-hydroxy-4-oxobutanoate + H2O + NADP(+) + trimethylamine


name: p-S MAPKAPK5 phosphorylates HSPB1 (Rattus norvegicus)


name: acetoacetate + ATP + CoA <=> acetoacetyl-CoA + AMP + diphosphate


name: 5'-deoxyadenosine + A + geneticin + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine => AH2 + gentamicin X2 + 2 S-adenosyl-L-methionine


name: (2S)-liquiritigenin + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + licodione + oxidized [NADPH--hemoprotein reductase]


name: (15Z)-tetracosenoyl-CoA + sphing-4-enine = CoA + H(+) + N-(15Z-tetracosenoyl)-sphing-4-enine


name: Autophosphorylation of PTK2 at Y397 (Homo sapiens)


name: DPPA2, DPPA4 and TP53 bind the DUX4 gene cluster (Homo sapiens)


name: SLMB binds phosphorylated cytosolic PER, facilitating its ubiquitination (Drosophila melanogaster)


name: IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Sus scrofa)


name: phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] => (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit]


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Homo sapiens)


name: H2O + NADP(+) + omega-hydroxy-15-methyl-hexadecanoate => 15-methylhexadecanoate + H(+) + NADPH + O2


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Homo sapiens)


name: 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] <=> dehydrocitreoisocoumarin + H2O + holo-[ACP]


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + phosphate


name: 2 Fe(III)-[cytochrome c] + H2O + lupanine => 17-hydroxylupanine + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: 1-hydroxy-6-methoxyphenazine + NADPH + O2 = 1-hydroxy-6-methoxyphenazine N(10)-oxide + H2O + NADP(+)


name: 4-hydroxybutanoate + NAD(+) => H(+) + NADH + succinate semialdehyde


name: neutral, basic amino acid:sodium:chloride symporter activity


name: 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA => (9Z,12Z)-octadecadienoyl-CoA + 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol


name: H2O + N(1)-acetylspermine <=> acetate + spermine


name: PREDN,PREDL diffuse into GI cells (Homo sapiens)


name: an acyl-CoA + dihydroxyacetone phosphate <=> a 1-acylglycerone 3-phosphate + CoA


name: Cytosolic PLK1 translocates to the nucleus (Sus scrofa)


name: MAPK8 phosphorylation (Caenorhabditis elegans)


name: Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Homo sapiens)


name: PKC-delta translocates to plasma membrane (Caenorhabditis elegans)


name: KIT binds type I TKIs (Xenopus tropicalis)


name: leukotriene B4 + O2 + reduced [NADPH--hemoprotein reductase] = 20-hydroxy-leukotriene B4 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Danio rerio)


name: ADRA2A,B,C bind ADR,NAd (Canis familiaris)


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O = ADP-alpha-D-ribose 1''-phosphate + H(+)


name: 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + formate + H(+)


name: Constitutive phosphorylation by GSK3 (Canis familiaris)


name: TNFSF11 binds TNFRSF11A, B (Rattus norvegicus)


name: SLIRP:LRPPRC binds mitochondrial RNAs (Homo sapiens)


name: Dopa is decarboxylated to dopamine (Homo sapiens)


name: atROL binds RBP1 to form RBP1:atROL (Rattus norvegicus)


name: ARSB hydrolyses C4S/C6S chains (Homo sapiens)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Rattus norvegicus)


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Homo sapiens)


name: Indirect recruitment of GAB2 to p-KIT (Homo sapiens)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Canis familiaris)


name: apoA-I binds to CUBN:AMN (Rattus norvegicus)


name: Caspase-mediated cleavage of claspin (Bos taurus)


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Xenopus tropicalis)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoate + H2O => (10S)-hydroxy-(6Z,12Z,15Z)-octadecatrienoate


name: calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Xenopus tropicalis)


name: USP17 deubiquitinates SUDS3 (Homo sapiens)


name: H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine => (5Z,8Z,11Z,14Z)-eicosatetraenoate + taurine


name: SMPD4 hydrolyzes sphingomyelin (ER membrane) (Mus musculus)


name: DLST transfers succinyl to CoA (Danio rerio)


name: (2E,6E)-farnesol + CTP => (2E,6E)-farnesyl phosphate + CDP + H(+)


name: a (Z)-N-(sulfonatooxy)alkanimidothioate <=> a nitrile + sulfate + sulfur


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Bos taurus)


name: D-galactose + sphing-4-enine => beta-D-galactosyl-(1<->1)-sphing-4-enine + H2O


name: Growing HA is extruded from the cell by ABCC5 (Sus scrofa)


name: SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Danio rerio)


name: cob(I)alamin + S-adenosyl-L-methionine = methylcob(III)alamin + S-adenosyl-L-homocysteine


name: NTPDase4 hydrolyzes nucleoside triphosphates (Bos taurus)


name: MVB Vesicle Formation (Rattus norvegicus)


name: (d)GMP or (d)IMP + H2O => (d)G or (d)I + orthophosphate (NT5C) (Homo sapiens)


name: E protein gets palmitoylated (Homo sapiens)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-choline = 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: (2E,6E)-farnesyl diphosphate + H2O = cubebol + diphosphate


name: NADP(+) + reduced coenzyme F420-(gamma-L-Glu)(n) <=> 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n)


name: GNB2L1 binds IKKA:IKKB:NEMO (Drosophila melanogaster)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA => 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA


name: 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oate + ATP + CoA = 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oyl-CoA + AMP + diphosphate


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Caenorhabditis elegans)


name: AKT can phosphorylate NR4A1 (NUR77) (Drosophila melanogaster)


name: glycine + hydrogen sulfide + NAD(+) => ADP-5-ethyl-4-methylthiazole-2-carboxylate + H(+) + 3 H2O + nicotinamide


name: H(+) + indole-3-pyruvate + NADPH + NH4(+) => H2O + L-tryptophan + NADP(+)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Mus musculus)


name: GDIs block activation of RHOA (Danio rerio)


name: GPR35 binds kynurenic acid (Gallus gallus)


name: Relaxin 3 receptor 1 binds relaxin 3 (Rattus norvegicus)


name: a 1-acyl-sn-glycerol + an acyl-CoA <=> a 1,3-diacyl-sn-glycerol + CoA


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Drosophila melanogaster)


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + H2O <=> (4Z,15Z)-bilirubin IXalpha + D-glucuronate + H(+)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Canis familiaris)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP => an N-acylsphing-4-enine + UDP-alpha-D-glucose


name: TGFBR3 translocation to plasma membrane (Homo sapiens)


name: DAXX binds Ub-MDM2 and USP7 (Bos taurus)


name: hydrogen cyanide + pentanal => (2S)-2-hydroxyhexanenitrile


name: ALK binds ALKAL ligand (Rattus norvegicus)


name: a 3',5'-unsubstituted flavanone + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = a 3',5'-dihydroxyflavanone + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: MAN2B1 hydrolyses GlcNAc (Man)5 to GlcNAc (Man)3 (Mus musculus)


name: SMPD4 hydrolyzes sphingomyelin (ER membrane) (Sus scrofa)


name: RHOU binds effectors at the plasma membrane (Schizosaccharomyces pombe)


name: H2O + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine <=> acetate + UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine


name: (9E)-octadecenoyl-CoA + hexadecan-1-ol = CoA + hexadecanyl (9E)-octadecenoate


name: Gq activation by TP receptor (Drosophila melanogaster)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Rattus norvegicus)


name: 5-hydroxyuridine(34) in tRNA + S-adenosyl-L-methionine = 5-methoxyuridine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: melanocyte-stimulating hormone receptor activity


name: guanyl-nucleotide exchange factor adaptor activity


name: GM2A binds and mobilizes ligands (Mus musculus)


name: 2-oxoadipate + CoA + NAD(+) => CO2 + glutaryl-CoA + NADH


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)


name: (1'S)-averantin + O2 + reduced [NADPH--hemoprotein reductase] => (1'S,5'S)-5'-hydroxyaverantin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylated FOXO1A is excluded from the nucleus (Drosophila melanogaster)


name: EPHB phosphorylates TIAM1 (Mus musculus)


name: SYK activation by SRC (Rattus norvegicus)


name: H2O + L-alanyl-tRNA(Pro) <=> H(+) + L-alanine + tRNA(Pro)


name: (2E,6E)-farnesyl diphosphate = (-)-alpha-isocomene + diphosphate


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Xenopus tropicalis)


name: deoxycholate + glycine => glycodeoxycholate + H2O


name: D-maltopentaono-1,5-lactone + H2O <=> D-maltopentaonate + H(+)


name: 5alpha-androstan-3,17-dione + A <=> AH2 + androst-4-ene-3,17-dione


name: L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: 4-amino-4-deoxy-beta-L-arabinopyranosyl-lipid A + di-trans,octa-cis-undecaprenyl phosphate => 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Saccharomyces cerevisiae)


name: 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+) => 5-(2-hydroxyethyl)-4-methylthiazole + ATP


name: STAT1 and STAT3 dimers translocate to the nucleus (Rattus norvegicus)


name: 3''-O-acetyl-ADP-D-ribose + H2O = acetate + ADP-D-ribose + H(+)


name: pyridoxamine 5'-phosphate + pyruvate => D-alanine + pyridoxal 5'-phosphate


name: H(+) + hyocholate 6-O-(beta-D-glucuronate) + UDP => hyocholate + UDP-alpha-D-glucuronate


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Drosophila melanogaster)


name: D-alanyl-5'-AMP + holo-[D-alanyl-carrier protein] <=> AMP + D-alanyl-[D-alanyl-carrier protein] + H(+)


name: ATG7:ATG3:LC3 dissociates (Caenorhabditis elegans)


name: Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA (Caenorhabditis elegans)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Bos taurus)


name: H2O + N(1)-acetylspermine + O2 => 3-acetamidopropanal + H2O2 + spermidine


name: P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential


name: azetidine-2-carboxylic acid acetyltransferase activity


name: 14-3-3 proteins bind AKT-phosphorylated FOXO1 (Homo sapiens)


name: 4-methylpent-2-enoyl-CoA + H2O => (R)-2-hydroxy-4-methylpentanoyl-CoA


name: Autophosphorylation of PDGF beta receptors (Sus scrofa)


name: 4 H(+) + 2 O2 + pentalenene + 4 reduced [2Fe-2S]-[ferredoxin] <=> 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al


name: SLC22A1 transports Cipro into renal cell (Bos taurus)


name: Anti-MET recombinant therapeutic antibodies bind MET (Canis familiaris)


name: CEBPA binds the promoter of the GFI1 gene (Homo sapiens)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Rattus norvegicus)


name: IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Homo sapiens)


name: PP2A mediated localization of RB1 protein in chromatin (Sus scrofa)


name: ARMS is phosphorylated by active TrkA receptor (Mus musculus)


name: NEIL3 cleaves spiroiminodihydantoin (Gallus gallus)


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Sus scrofa)


name: Collagen type XII degradation by MMP12 (Bos taurus)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Canis familiaris)


name: (9E)-octadecenoyl-CoA + FAD + H(+) <=> (2E,9E)-octadecadienoyl-CoA + FADH2


name: a ganglioside GD1a + acetyl-CoA = a ganglioside Ac-O-7-GD1a + CoA


name: 6 Fe(III)-[cytochrome c] + 2 H2O + NH4(+) <=> 6 Fe(II)-[cytochrome c] + 8 H(+) + nitrite


name: IFNG dimer binds IFNG inhibitors (Gallus gallus)


name: dipeptide transmembrane transporter activity


name: ADORA2A,B bind Ade-Rib (Caenorhabditis elegans)


name: Tenascins C, R, (X, N) bind lecticans (Sus scrofa)


name: CYTH proteins stimulate ARF1 GTPase activity (Bos taurus)


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-3-[beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 1-(9Z,12Z-octadecadienoyl)-2-acyl-3-[beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: SENP1,2,5 proteolytically process SUMO2 (Xenopus tropicalis)


name: KDM5A-D demethylate Me2K5-histone H3 (Schizosaccharomyces pombe)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone <=> 6beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Dictyostelium discoideum)


name: 12alpha,13alpha-dihydroxyfumitremorgin C + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => fumitremorgin C + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine => 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP


name: (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + NADP(+)


name: alpha-D-glucosamine 1-phosphate => D-glucosamine 6-phosphate


name: ERBB3 binds RNF41 ubiquitin ligase (Rattus norvegicus)


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Drosophila melanogaster)


name: 5-phospho-alpha-D-ribose 1-diphosphate + neamine <=> 5''-phosphoribostamycin + diphosphate


name: (S)-4-aminopentanoate + H2O + NAD(+) => 4-oxopentanoate + H(+) + NADH + NH4(+)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Homo sapiens)


name: Hh-Npp binds GAS1 and PTCH (Homo sapiens)


name: Caspase-8 and FLIP(L) processing at DISC (Canis familiaris)


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Mus musculus)


name: a 12-oxojasmonyl-L-alpha-amino acid + O2 + reduced [NADPH--hemoprotein reductase] = a 12-hydroxy-12-oxojasmonyl-L-alpha-amino acid + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Caenorhabditis elegans)


name: HOXD1 gene is transcribed (Homo sapiens)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Caenorhabditis elegans)


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Plasmodium falciparum)


name: Expression of Carbonic anhydrase 1 (Homo sapiens)


name: a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+) => a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose


name: Association of procollagen type III (Caenorhabditis elegans)


name: p-Y705-STAT3,p-Y641-STAT6 dissociate (Bos taurus)


name: (2-aminoethyl)phosphonate + pyruvate => L-alanine + phosphonoacetaldehyde


name: Dimerization of STATs (Xenopus tropicalis)


name: 2-O,3-O-dihexadecanoyl-alpha,alpha-trehalose + CoA => 2-O-hexadecanoyl-alpha,alpha-trehalose + hexadecanoyl-CoA


name: Dopa is oxidized to dopaquinone by TYR (Canis familiaris)


name: ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Xenopus tropicalis)


name: guanosine 3'-diphosphate 5'-triphosphate + H2O <=> diphosphate + GTP + H(+)


name: ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 (Canis familiaris)


name: Cu(2+)(out) + L-ascorbate(in) => Cu(+)(out) + H(+) + monodehydro-L-ascorbate radical(in)


name: CBL ubiquitinates FRS2 and FGFR4 (Mus musculus)


name: The orphan QRFP receptor can bind neuropeptide QRFP (Canis familiaris)


name: HIF-alpha translocates from cytosol to nucleus (Drosophila melanogaster)


name: ATP + L-arginine = ADP + H(+) + N(omega)-phospho-L-arginine


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Homo sapiens)


name: 6alpha-hydroxy-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase] => 28-nortyphasterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 6-amino-2-oxohexanoate + H2O2 => 5-aminopentanoate + CO2 + H2O


name: H2O + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD(+) = (S)-2,3-diaminopropanoate + 2-oxoglutarate + H(+) + NADH


name: UDP-N-acetyl-alpha-D-glucosamine(in) + UMP(out) = UDP-N-acetyl-alpha-D-glucosamine(out) + UMP(in)


name: HSBP1 oligomer binds ESRs (Gallus gallus)


name: H2O + isomaltose = beta-D-glucose + D-glucose


name: 4,8-dimethylnonanoyl-CoA + carnitine => 4,8-dimethylnonanoylcarnitine + CoASH (Rattus norvegicus)


name: SEC4C,D bind GOSR2 and STX5 (Mus musculus)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Caenorhabditis elegans)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Sus scrofa)


name: RET tyrosine phosphorylation (Gallus gallus)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Dictyostelium discoideum)


name: Budding of COPII coated vesicle (Canis familiaris)


name: CBL binds to GRB2 (Caenorhabditis elegans)


name: 1D-myo-inositol 3-phosphate + CDP-2,3-bis-O-(phytanyl)-sn-glycerol => CMP + H(+) + saturated 1-archaetidyl-1D-myo-inositol 3-phosphate


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Mus musculus)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Danio rerio)


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Homo sapiens)


name: SHC1 phosphorylation by ERBB2 heterodimers (Bos taurus)


name: 1-O-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + H(+) + succinate


name: guaethol + O2 + reduced [NADH--hemoprotein reductase] <=> acetaldehyde + catechol + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: L-idonate + NADP(+) => 5-dehydro-D-gluconate + H(+) + NADPH


name: atrochrysone carboxylate + H(+) + holo-[ACP] => atrochrysone carboxyl-[ACP] + H2O


name: Dissociation of the TP:Gq complex (Homo sapiens)


name: 3-(all-trans-decaprenyl)benzene-1,2-diol + H2O + NADP(+) => 2-all-trans-decaprenylphenol + H(+) + NADPH + O2


name: 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + H2O => 1-hexadecanoyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Dictyostelium discoideum)


name: ent-kaur-16-en-19-al + H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => ent-kaur-16-en-19-oate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Active ARF recruits coatomer to the Golgi (Mus musculus)


name: CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Bos taurus)


name: ABCC2 transports BMG,BDG from cytosol to extracellular region (Drosophila melanogaster)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Rattus norvegicus)


name: Caspase-mediated cleavage of Lamin A (Gallus gallus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: 3xPPCDC:3FMN decarboxylates PPC (Canis familiaris)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Canis familiaris)


name: ATP + L-aspartate + NH4(+) <=> AMP + diphosphate + H(+) + L-asparagine


name: NFkB complex translocates from the cytosol to the nucleus (Danio rerio)


name: pS181-S-Farn-Me KRAS4B binds BCL2L1 (Gallus gallus)


name: IL1F10 binds IL1RAPL1 (Xenopus tropicalis)


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Bos taurus)


name: IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Gallus gallus)


name: (E)-anol + S-adenosyl-L-methionine <=> (E)-anethole + H(+) + S-adenosyl-L-homocysteine


name: p-S60,S186-ZFP36 (Tristetraproline, TTP) binds 14-3-3beta (Bos taurus)


name: Oxidative damage to the AP site (Xenopus tropicalis)


name: Calmodulin-bound CaMKII-gamma enters the nucleus (Homo sapiens)


name: FURIN binds furin inhibitors (Homo sapiens)


name: 1,3-dinitrobenzene + NADH + O2 <=> 4-nitrocatechol + H(+) + NAD(+) + nitrite


name: H(+)(in) + L-methionine(out) => H(+)(out) + L-methionine(in)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Sus scrofa)


name: CYP51A1 demethylates LNSOL (Saccharomyces cerevisiae)


name: 2-oxoglutarate(out) + 3 Na(+)(out) => 2-oxoglutarate(in) + 3 Na(+)(in)


name: FOXO1,FOXO3 bind PINK1 gene promoter (Homo sapiens)


name: cytosine(in) + H(+)(in) => cytosine(out) + H(+)(out)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Bos taurus)


name: Activated NTRK3 stimulates PI3K activity (Homo sapiens)


name: 6-decylubiquinone + 2 thiosulfate <=> 6-decylubiquinol + tetrathionate


name: CDP-DAG is converted to PI by CDIPT (Mus musculus)


name: Acitretin binds to RAR:RXR (Drosophila melanogaster)


name: CARNMT1 methylates CARN to Anserine (Sus scrofa)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Caenorhabditis elegans)


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Gallus gallus)


name: L-aspartate(in) + L-phenylalanine(out) <=> L-aspartate(out) + L-phenylalanine(in)


name: 6alpha-hydroxy-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase] = 28-nortyphasterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: 6-diphospho-1D-myo-inositol pentakisphosphate + H2O <=> 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + gamma-muurolene


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Drosophila melanogaster)


name: 1-(11Z-eicosenoyl)-glycerol + H2O => (11Z)-eicosenoate + glycerol + H(+)


name: L-arabinitol + NAD(+) = H(+) + L-ribulose + NADH


name: Fibrillin C-terminal processing (Bos taurus)


name: Ferrous iron reduces the BH3 radical back to BH4 (Homo sapiens)


name: Endocytosis and degradation of apoA-I (Homo sapiens)


name: Fall Back to Closed Pre-initiation Complex (Drosophila melanogaster)


name: CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + tetracosanoyl-CoA


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Dictyostelium discoideum)


name: ATP + L-rhamnulose = ADP + H(+) + L-rhamnulose 1-phosphate


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: (R)-benzoin + NADP(+) <=> benzil + H(+) + NADPH


name: S-adenosyl-L-methionine + uridine(1939) in 23S rRNA <=> 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: NADPH transfers electrons to FDXR (Schizosaccharomyces pombe)


name: p62 links damaged mitochondria to LC3 (Danio rerio)


name: SYK binds to p-Y65,Y76-FCER1G (Canis familiaris)


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Danio rerio)


name: HERC2 and PIAS4 are recruited to DNA DSBs (Canis familiaris)


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Saccharomyces cerevisiae)


name: OSM,LIF,CTF1 receptor complex binds gp130 (Mus musculus)


name: n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate <=> n adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate + n H(+)


name: AH2 + chrodrimanin C => 3-hydroxypentacecilide A + A


name: histone H3K4 trimethyltransferase activity


name: CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter (Rattus norvegicus)


name: diphosphate + gamma-himachalene => (2E,6E)-farnesyl diphosphate


name: a triacyl-sn-glycerol + H2O = a 1,2-diacyl-sn-glycerol + a fatty acid + H(+)


name: G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t) (Canis familiaris)


name: RAC3 binds effectors at the plasma membrane (Xenopus tropicalis)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Bos taurus)


name: HSPG binds LPL dimer (Rattus norvegicus)


name: 2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine <=> diphthine-[translation elongation factor 2] + H(+) + S-adenosyl-L-homocysteine


name: COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Sus scrofa)


name: DCC interaction with Ezrin (Drosophila melanogaster)


name: 5-oxo-L-proline(out) + 2 Na(+)(out) <=> 5-oxo-L-proline(in) + 2 Na(+)(in)


name: Phosphorylation of CTLA-4 (Rattus norvegicus)


name: DERA cleaves dR5P to GA3P and CH3CHO (Drosophila melanogaster)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Saccharomyces cerevisiae)


name: IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol (Gallus gallus)


name: (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O = pyruvate + salicylaldehyde


name: an L-alpha-amino acid + glycocholate <=> an N-choloyl-L-alpha-amino acid + glycine


name: CO2 + hydroquinone => 2,5-dihydroxybenzoate + H(+)


name: chloroorienticin B + dTDP + H(+) => devancoaminyl-vancomycin + dTDP-beta-L-4-epi-vancosamine


name: Phosphorylated DVL recruits PIP5K1B to the plasma membrane (Mus musculus)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Rattus norvegicus)


name: 2 H(+) + H2O + licodione + oxidized [NADPH--hemoprotein reductase] => (2S)-liquiritigenin + O2 + reduced [NADPH--hemoprotein reductase]


name: (R)-6-hydroxynicotine + H2O + O2 <=> 6-hydroxypseudooxynicotine + H2O2


name: ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Canis familiaris)


name: FNTB inhibitors bind FNTA:FNTB (Mus musculus)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Gallus gallus)


name: Bile salts and acids bind ALB (Sus scrofa)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = astellifadiene + diphosphate


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Drosophila melanogaster)


name: H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2 = (1-deoxy-D-fructos-1-yl)amine + glyoxylate + H2O2


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Homo sapiens)


name: ST6GALNAC5,6 transfer Neu5Ac to GM1b (Xenopus tropicalis)


name: L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine <=> H(+) + N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine


name: AMP + diphosphate => 5-phospho-alpha-D-ribose 1-diphosphate + adenine


name: cytidine(40) in tRNA precursor + S-adenosyl-L-methionine => 5-methylcytidine(40) in tRNA precursor + H(+) + S-adenosyl-L-homocysteine


name: DHTKD1 dimer decarboxylates 2-OA (Drosophila melanogaster)


name: Release of 40S and 60S subunits from the 80S ribosome  (Saccharomyces cerevisiae)


name: guanosine(527) in 16S rRNA + S-adenosyl-L-methionine <=> N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine


name: dADP + H2O = 2'-deoxyadenosine + diphosphate


name: Degradation of ubiquitinated beta catenin by the proteasome (Rattus norvegicus)


name: HIRA and NPM2 assemble H3.3-containing nucleosomes on paternal DNA (Homo sapiens)


name: 9-cis-retinol + a fatty acyl-CoA => 9-cis-retinyl ester + CoA


name: Trafficking of nonameric complex in the endocytic pathway (Canis familiaris)


name: GCL ligates L-Glu to L-Cys (Canis familiaris)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP


name: RIOX2Fe2+ hydroxylates a histidine residue of RPL27A (Bos taurus)


name: 2 (3R)-hydroxy-beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial => all-trans-zeaxanthin + 2 O2


name: B3GALTs transfer Gal to GlcNAc-β1,3-Gal-R to form Type 1 chain (Xenopus tropicalis)


name: TIMM22 inserts proteins into inner membrane (Homo sapiens)


name: Cleavage of thymine glycol by NTHL1 glycosylase   (Sus scrofa)


name: GTP + methylglyoxal => N(2)-(1-hydroxy-2-oxopropyl)-GTP


name: Apelin receptor binds to apelin (Sus scrofa)


name: cholesterol 7-desaturase (NAD(P)H) activity


name: phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate (Homo sapiens)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate => a ganglioside GM4 (d18:1(4E)) + CMP + H(+)


name: (S)-2-hydroxyglutarate + FAD + H(+) = 2-oxoglutarate + FADH2


name: CoA + H(+) + N(6)-acyl-L-lysyl-[protein] => an acyl-CoA + L-lysyl-[protein]


name: LIPs hydrolyse TG to DAG and RCOOH (Bos taurus)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Dictyostelium discoideum)


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Plasmodium falciparum)


name: CSF3 dimer:CSFR binds CSFR (Gallus gallus)


name: [thioredoxin]-dithiol + arsenic triglutathione + 2 H2O + S-adenosyl-L-methionine => [thioredoxin]-disulfide + 3 glutathione + H(+) + methylarsonous acid + S-adenosyl-L-homocysteine


name: Microtubule-independent trafficking of connexons to the plasma membrane (Gallus gallus)


name: FAAH2 hydrolyses AEA to AA and ETA (Danio rerio)


name: (2R,3S)-3-methylmalate + NAD(+) <=> 2-oxobutanoate + CO2 + NADH


name: CTP + D-ribulose 5-phosphate + H(+) = CDP-D-ribulose + diphosphate


name: (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + H(+) + phosphate => (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ATP + L-glutamate


name: ATP + dodecanoate(out) + H2O => ADP + dodecanoate(in) + H(+) + phosphate


name: (4R)-hydroxysphinganine + eicosanoyl-CoA => CoA + H(+) + N-eicosanoyl-(4R)-hydroxysphinganine


name: 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose <=> (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + H(+) + UDP


name: H2O + orobanchol => 5-hydroxy-3-methylfuran-2(5H)-one + orobanchol ABC-rings


name: Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Xenopus tropicalis)


name: 10,13-dihydroxyoctadecanoate => (12Z)-10-hydroxyoctadecenoate + H2O


name: (E)-feruloyl-CoA + L-quinate <=> 4-O-feruloyl-D-quinate + CoA


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Sus scrofa)


name: bilirubin IXalpha bis-beta-D-glucuronoside(out) <=> bilirubin IXalpha bis-beta-D-glucuronoside(in)


name: IFNL1 binds IL10RB:TYK2 and IFNLR1:JAK1 (Homo sapiens)


name: AGT(34-41) binds to AGTR2 (Drosophila melanogaster)


name: Association of HMGB1/HMGB2 with chromatin (Danio rerio)


name: CHMP7 binds CC2D1B (Drosophila melanogaster)


name: (2R,3S)-iso(homo)2citrate + NAD(+) => 2-oxoheptanedioate + CO2 + NADH


name: Clathrin-Mediated Pit Formation And Endocytosis Of The Influenza Virion (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + quercetin => adenosine 3',5'-bisphosphate + H(+) + quercetin 3-sulfate


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)


name: NAD(+) + xylitol <=> D-xylulose + H(+) + NADH


name: Collagen type I degradation by MMP1,2,8,13, PRSS2 (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 3-hexadecanoyl-sn-glycerol = 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: H(+) + meleagrin + S-adenosyl-L-homocysteine => glandicoline B + S-adenosyl-L-methionine


name: Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Xenopus tropicalis)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Canis familiaris)


name: POLZ elongates POLI-incorporated dNMP (Saccharomyces cerevisiae)


name: CYP3A4, CYP2B6 bind ritonavir (Danio rerio)


name: PTPN11 dephosphorylates RUNX1 (Homo sapiens)


name: guanosine(6) in tRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(6) in tRNA + S-adenosyl-L-homocysteine


name: H(+)(in) + L-rhamnopyranose(in) => H(+)(out) + L-rhamnopyranose(out)


name: An unknown reductase reduces D-UBGN to STBN (Homo sapiens)


name: (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) = 2-methyl-3-oxobutanoyl-CoA + H(+) + NADH


name: dihydrochelirubine + NADP(+) <=> chelirubine + NADPH


name: ANOs transport cytosolic Cl- to extracellular region (Mus musculus)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Drosophila melanogaster)


name: CDK1 phosphorylates lamins and facilitates depolymerization of lamin filaments (Sus scrofa)


name: 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA => a 1-acyl-sn-glycero-3-phosphoethanolamine + octanoyl-CoA


name: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine = H(+) + menaquinol-8 + S-adenosyl-L-homocysteine


name: 1-methylimidazole-4-acetaldehyde + H2O2 + NH4(+) => H2O + N(tau)-methylhistamine + O2


name: (-)-(R)-19-hydroxytabersonine + acetyl-CoA => (-)-(R)-19-O-acetyltabersonine + CoA


name: Fe(III)-heme b-[protein] + H2O + nitric oxide => Fe(II)-heme b-[protein] + 2 H(+) + nitrite


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Drosophila melanogaster)


name: 3-methyl-2-oxobutanoate(out) + H(+)(out) = 3-methyl-2-oxobutanoate(in) + H(+)(in)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + silphinene = 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + silphinene-15-oate


name: 3-hydroxypropanal + H2O + NAD(+) = 3-hydroxypropanoate + 2 H(+) + NADH


name: D-aspartate + H(+) + tRNA(Asp) => D-aspartyl-tRNA(Asp) + H2O


name: 3,3',5-triiodo-L-thyronine(out) + L-glutamate(in) <=> 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out)


name: ATP + N-acetyl-D-muramate => ADP + H(+) + N-acetyl-D-muramate 6-phosphate


name: small RNA binding translational repressor activity


name: HYAL1 hydrolyses Chondroitin chains (Xenopus tropicalis)


name: 5-oxo-EPA, 15d-PGJ3 translocate from cytosol to extracellular region (Homo sapiens)


name: (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA => (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) => a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: O2 + prostaglandin H1 + reduced [NADPH--hemoprotein reductase] => 19-hydroxyprostaglandin H1 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + ATP + CoA => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + AMP + diphosphate


name: 2 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+) => 2 L-dopa + O2


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Homo sapiens)


name: Exocytosis of platelet dense granule content (Homo sapiens)


name: Formation of NELF complex  (Drosophila melanogaster)


name: factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain (Bos taurus)


name: (11R)-dihydroartemisinic aldehyde + H2O + NAD(+) = (11R)-dihydroartemisinate + 2 H(+) + NADH


name: MIR181C microRNA binds 3'UTR of NOTCH4 mRNA (Homo sapiens)


name: 2 (2E,6E)-farnesyl diphosphate + H(+) + NADH <=> 2 diphosphate + NAD(+) + squalene


name: L-arginine(in) + L-leucine(out) => L-arginine(out) + L-leucine(in)


name: (E)-4-coumaroyl alcohol + NADP(+) => (E)-4-coumaraldehyde + H(+) + NADPH


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine = (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: histone H4K12 methyltransferase activity


name: Recruitment of SYK to phosphorylated ITAMs (Bos taurus)


name: ABCA7:Apo1A-mediated phospholipid efflux (Homo sapiens)


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: chlorate transmembrane transporter activity


name: Pro-beta-NGF and mature beta-NGF are secreted (Bos taurus)


name: LUM (lumican) binds integrin alpha2beta1 (Gallus gallus)


name: SCF-mediated degradation of Emi1 (Rattus norvegicus)


name: SLC45A3 transports Glc from extracellular region to cytosol (Schizosaccharomyces pombe)


name: Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Caenorhabditis elegans)


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Caenorhabditis elegans)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)


name: RAC2 translocates to the ER membrane (Rattus norvegicus)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Sus scrofa)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Bos taurus)


name: 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA => (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: XDH dehydrogenates hypoxanthine to form xanthine (Rattus norvegicus)


name: Active G alpha (q) binds RGS proteins (Mus musculus)


name: 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine => 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + H(+) + UDP


name: formate + propanoyl-CoA => 2-oxobutanoate + CoA


name: 5,6-dihydrouracil + H2O => beta-ureidopropionate (Dictyostelium discoideum)


name: IL3 stimulation induces Vav binding to Tec kinase (Rattus norvegicus)


name: a long-chain (3S)-3-hydroxy fatty acyl-CoA = a long-chain (2E)-enoyl-CoA + H2O


name: 5 H(+) + 3 O2 + obtusifoliol + 6 reduced [2Fe-2S]-[ferredoxin] => 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: carbamoyl phosphate + oxamate = N-carbamoyl-2-oxoglycine + phosphate


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Bos taurus)


name: 3-oxohexanoyl-[ACP] + H(+) + NADPH = (3R)-hydroxyhexanoyl-[ACP] + NADP(+)


name: ITCH ubiquitinates DTX (Drosophila melanogaster)


name: MBD2 binds methylcytosine in chromatin (Xenopus tropicalis)


name: AXIN is ubiquitinated by SMURF2 (Bos taurus)


name: 1-(9Z-octadecenoyl)-glycerol + H2O <=> (9Z)-octadecenoate + glycerol + H(+)


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Caenorhabditis elegans)


name: MTMR12 binds MTM1 (Drosophila melanogaster)


name: USP9X (FAM) binds to ubiquitinated SMAD4 (Mus musculus)


name: RUNX3 binds TEADs and YAP1 (Homo sapiens)


name: ABCB4 transports PC from plasma membrane to extracellular region (Mus musculus)


name: p38MAPK phosphorylates MSK1 (Saccharomyces cerevisiae)


name: PXLP-K56-SRR dimer deaminates D-Ser (Xenopus tropicalis)


name: Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Xenopus tropicalis)


name: a D-glucoside + NAD(+) = a 3-dehydro-D-glucoside + H(+) + NADH


name: 7-deoxyloganin + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + loganin + oxidized [NADPH--hemoprotein reductase]


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Rattus norvegicus)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Xenopus tropicalis)


name: p-S215 FOXO3 translocates to the nucleus (Sus scrofa)


name: N-(4-aminobutyl)-3-aminopropanal = acrolein + putrescine


name: 3 Na(+)(out) + thiosulfate(out) <=> 3 Na(+)(in) + thiosulfate(in)


name: 3'-phosphoadenylyl sulfate + an alcohol => adenosine 3',5'-bisphosphate + an alkyl sulfate + H(+)


name: PGG2 is reduced to PGH2 by PTGS2 (Bos taurus)


name: [thioredoxin]-disulfide + H2O + tert-butanol => [thioredoxin]-dithiol + tert-butyl hydroperoxide


name: a 2-arylethylamine + acetyl-CoA <=> an N-acetyl-2-arylethylamine + CoA + H(+)


name: NMRK2 phosphorylates NAR to yield NAMN (Danio rerio)


name: RHOD translocates to the mitochondrial outer membrane (Saccharomyces cerevisiae)


name: USP13 and OTUD3 deubiquitinate PTEN (Mus musculus)


name: mTORC1 binds RHEB:GTP (Xenopus tropicalis)


name: EFCAB7:IQCE binds EVC2:EVC (Xenopus tropicalis)


name: ADP(in) + dATP(out) = ADP(out) + dATP(in)


name: FKBP1A binds sirolimus (Rattus norvegicus)


name: Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV (Drosophila melanogaster)


name: phosphatidylinositol bisphosphate phosphatase activity


name: 2 L-tyrosyl-tRNA(Tyr) => cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)


name: GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol (Danio rerio)


name: USP9X (FAM) deubiquitinates SMAD4 (Homo sapiens)


name: CHST3,7 transfer SO4(2-) to position 6 of GalNAc on chondroitin chains (Xenopus tropicalis)


name: 3'-phosphoadenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol => 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: D-sorbitol + NADP(+) = H(+) + L-xylo-3-hexulose + NADPH


name: CX3 complex formation (Canis familiaris)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Rattus norvegicus)


name: NADPH + pentaerythritol trinitrate <=> NADP(+) + nitrite + pentaerythritol dinitrate


name: H2O + N(omega)-(ADP-D-ribosyl)-L-arginine => ADP-D-ribose + L-arginine


name: 2xSOD1:CCS:Zn2+:2xCu1+ dimer dissociates (Homo sapiens)


name: (S)-3'-hydroxy-N-methylcoclaurine + S-adenosyl-L-methionine = (S)-reticuline + H(+) + S-adenosyl-L-homocysteine


name: deoxyspectinabilin + S-adenosyl-L-homocysteine => demethyldeoxyspectinabilin + S-adenosyl-L-methionine


name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor


name: TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Dictyostelium discoideum)


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Homo sapiens)


name: D-arabinose(out) + H(+)(out) => D-arabinose(in) + H(+)(in)


name: Extracellular KSPG translocates to the lysosome for degradation (Xenopus tropicalis)


name: TCN2 binds RCbl in the circulation (Bos taurus)


name: PREX2 binds PTEN and inhibits it (Xenopus tropicalis)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Schizosaccharomyces pombe)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Drosophila melanogaster)


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Canis familiaris)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Canis familiaris)


name: USP30 deubiquitinates Ub-MOM proteins (Drosophila melanogaster)


name: ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Xenopus tropicalis)


name: 3-dehydro-L-gulonate + H(+) + NADH => L-gulonate + NAD(+)


name: Dissociation of the P2Y purinoceptor 12:Gi complex (Mus musculus)


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Danio rerio)


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = a 1-acyl-2-[(9Z)-hexadecenoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: CBCAP complex binds 7-methylguanosine cap of snRNA (Bos taurus)


name: hexadecanoate + NH4(+) => H2O + hexadecanamide


name: AMP + ATP <=> ADP + ADP [AK2] (Homo sapiens)


name: The receptor:G-protein complex  binds GTP (Rattus norvegicus)


name: Formation of the closed pre-initiation complex (Homo sapiens)


name: S-adenosyl-L-methionine transmembrane transporter activity


name: SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy (Homo sapiens)


name: UGT1A4 transfers GlcA from UDP-GlcA to BMG to form BDG (Rattus norvegicus)


name: ADP + D-glucose 6-phosphate + H(+) => ATP + D-glucose


name: 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + ATP + CoA = 5-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + AMP + diphosphate


name: MECP2 binds the PVALB gene promoter (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+)


name: Phospho-R-Smad1/5/8 dissociates from the receptor complex (Mus musculus)


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + S-adenosyl-L-methionine = a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide + H(+) + S-adenosyl-L-homocysteine


name: ATP + choline(out) + H2O <=> ADP + choline(in) + H(+) + phosphate


name: RHOBTB2 binds interacting proteins at the endosome membrane (Drosophila melanogaster)


name: SUMOylation of HDAC1 with SUMO1 (Gallus gallus)


name: A + a 3-oxo-Delta(1)-steroid + H2O <=> a steroid 1,3-dione + AH2


name: Excess homocysteine yields homolanthionine and H2S (Drosophila melanogaster)


name: 2-hydroxyglutarate + acetyl-CoA => 2-hydroxyglutaryl-CoA + acetate


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a monoacyl-sn-glycero-3-phosphocholine + H(+) + N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: Photons induce isomerization of 11c-retinyl to at-retinyl (Bos taurus)


name: 2,2-dimethylsuccinate(in) + 3 Na(+)(in) => 2,2-dimethylsuccinate(out) + 3 Na(+)(out)


name: VCAM1 binds Integrin alpha4beta1 (Mus musculus)


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)


name: Calmodulin dissociates KRAS4B from the plasma membrane (Gallus gallus)


name: Cleavage of Procaspase-3 by the apoptosome (Xenopus tropicalis)


name: chloride(out) + hydrogencarbonate(in) => chloride(in) + hydrogencarbonate(out)


name: UNC93B1 delivers endosomal full-length TLRs to endolysosome (Homo sapiens)