name: L-asparagine(out) + L-glutamine(in) + Na(+)(in) => L-asparagine(in) + L-glutamine(out) + Na(+)(out)


name: L-arginyl-tRNA(Arg) + L-prolyl-tRNA(Pro) = cyclo(L-arginyl-L-prolyl) + 2 H(+) + tRNA(Arg) + tRNA(Pro)


name: PGJ3 isomerises to δ12-PGJ3 (Homo sapiens)


name: SULT dimers sulfate APAP to APAP-SO3 (Xenopus tropicalis)


name: SUMOylation of HDAC1 with SUMO1 (Schizosaccharomyces pombe)


name: [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + H(+) + S-adenosyl-L-homocysteine


name: MSH2:MSH6 exchanges ADP for ATP (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate <=> alpha-thujene + diphosphate


name: a dicarboxylate(in) + L-erythro-7,8-dihydrobiopterin(out) => a dicarboxylate(out) + L-erythro-7,8-dihydrobiopterin(in)


name: H2O + L,L-cystathionine => L-homocysteine + L-serine


name: Defective MGAT2 does not transfer GlcNAc to N-glycans (Homo sapiens)


name: S-ethyl-L-cysteine <=> 2-aminoprop-2-enoate + ethanethiol


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> 1-O-alkyl-2-acetyl-3-acylglycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Gallus gallus)


name: 2-methylbutanoyl-CoA + H2O <=> 2-methylbutanoate + CoA + H(+)


name: 3-dehydro-6alpha-hydroxyteasterone + O2 + reduced [NADPH--hemoprotein reductase] <=> 3-dehydroteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Exocytosis of tertiary granule lumen proteins (Canis familiaris)


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Rattus norvegicus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 => (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: ABCB9 transports peptides from cytosol to lysosomal lumen (Caenorhabditis elegans)


name: 2'-deoxyxanthosine + NH4(+) => 2'-deoxyguanosine + H(+) + H2O


name: chloride(out) + L-arginine(out) + 2 Na(+)(out) => chloride(in) + L-arginine(in) + 2 Na(+)(in)


name: NOTCH3 binds activated EGFR (Homo sapiens)


name: CO2 + H(+) + hexanal + succinate + sulfate => 2-oxoglutarate + hexyl sulfate + O2


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+)


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Dictyostelium discoideum)


name: SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Sus scrofa)


name: MTMR4 binds phosphorylated SMAD2/3 (Xenopus tropicalis)


name: 5-(methylsulfanyl)-D-ribose + ATP = ADP + H(+) + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Xenopus tropicalis)


name: Ubiquitinated IkB is degraded (Drosophila melanogaster)


name: Inhibition of integrin activation by sequestering PIP5KIgamma (Bos taurus)


name: oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: Hydrolysis of internal thioester in C4b (Bos taurus)


name: Collagen type XV restin release (Homo sapiens)


name: STING recruits TBK1 and IRF3 (Homo sapiens)


name: 4-coumaroyl-CoA + S-adenosyl-L-methionine = CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine


name: a globoside Gb4Cer + N-acetyl-alpha-D-galactosamine => a globoside IV3GalNAc-Gb4Cer + H2O


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Xenopus tropicalis)


name: (2S)-2-amino-3-oxobutanoate + H(+) = aminoacetone + CO2


name: ALB binds extracellular heme (Bos taurus)


name: an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => an (11Z,14Z)-icosadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: MHC class II antigen processing (Danio rerio)


name: Binding of CBL to EGFR (Caenorhabditis elegans)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Caenorhabditis elegans)


name: 2-oxoglutarate + AH2 + fumitremorgin B + 2 O2 => A + CO2 + H2O + succinate + verruculogen


name: CUL3:RBX1 ubiquitinates KEAP1 (Caenorhabditis elegans)


name: UBXN1 binds BRCA1:BARD1 heterodimer (Bos taurus)


name: a 6-phospho-beta-D-galactoside + H2O <=> an alcohol + D-galactose 6-phosphate


name: RAC1:GTP binds NOX3 complex (Homo sapiens)


name: (6S)-5,6,7,8-tetrahydrofolate + O2 + sarcosine = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O2


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Xenopus tropicalis)


name: Proinsulin binds zinc and calcium forming Proinsulin:zinc:calcium (Canis familiaris)


name: Activated FGFR1 binds FLRT1,2,3 (Rattus norvegicus)


name: 5,6-dihydrothymine + H2O <=> 3-(carbamoylamino)-2-methylpropanoate + H(+)


name: KPNA2 translation is negatively regulated by miR-26A and B (Homo sapiens)


name: PTEN undergoes monoubiquitination (Gallus gallus)


name: 2 H2O + UTP => 2 H(+) + 2 phosphate + UMP


name: cholesta-5,7-dien-3beta,24S-diol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 7-dehydrocholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: TRIF:activated TLR3/TLR4 complex recruits RIP1 (Homo sapiens)


name: CNIH1 binds TFGA and AREG precursors (Mus musculus)


name: NTRK3 dimers trans-autophosphorylate (Rattus norvegicus)


name: H(+) + malonyl-[ACP] + pentanoyl-CoA => 3-oxoheptanoyl-[ACP] + CO2 + CoA


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) + phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Homo sapiens)


name: guanosine(10) in tRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(10) in tRNA + S-adenosyl-L-homocysteine


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Plasmodium falciparum)


name: a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid + 8 oxidized 2[4Fe-4S]-[ferredoxin] => a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 16 H(+) + 8 reduced 2[4Fe-4S]-[ferredoxin]


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Drosophila melanogaster)


name: D-mannose(out) + n Na(+)(out) <=> D-mannose(in) + n Na(+)(in)


name: Caspase-6 translocates to the nucleus (Homo sapiens)


name: dibenzothiophene 5-oxide + FMNH2 + O2 => dibenzothiophene 5,5-dioxide + FMN + H(+) + H2O


name: MECP2 binds the SIN3A co-repressor complex (Sus scrofa)


name: Caspase-mediated cleavage of alpha adducin (Gallus gallus)


name: UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Rattus norvegicus)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Homo sapiens)


name: 11beta,17beta-dihydroxyandrost-4-ene-3-one + NAD(+) <=> 17beta-hydroxyandrost-4-ene-3,11-dione + H(+) + NADH


name: Ubiquitination of stimulated EGFR (CBL) (Caenorhabditis elegans)


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Gallus gallus)


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Sus scrofa)


name: a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O => a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-acyl-2-[(R)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + H2O


name: ALKBH3 associated with ASCC1:ASCC2:ASCC3 binds alkylated dsDNA containing 1-meA (Homo sapiens)


name: di-(9Z)-octadecenoylglycerol + H2O => (9Z)-octadecenoate + (9Z-octadecenoyl)-glycerol + H(+)


name: acetyl-CoA + streptothricin D = CoA + H(+) + N(beta)-acetylstreptothricin D


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Plasmodium falciparum)


name: Recruitment of SYK to p-DAP12 (Gallus gallus)


name: (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + H2O => (-)-geosmin


name: a ganglioside Ac-O-9-GD3 + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside Ac-O-9-GD2 + H(+) + UDP


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Dictyostelium discoideum)


name: a phenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] => a methoxylated aromatic compound + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: RHOF auto-activates (Caenorhabditis elegans)


name: (6R)-5,10-methenyltetrahydrofolate + H2O <=> (6S)-5-formyl-5,6,7,8-tetrahydrofolate + H(+)


name: 2-oxoglutarate + beta-alanine => 3-oxopropanoate + L-glutamate


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Gallus gallus)


name: 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Mus musculus)


name: FA2H hydroxylates 1,2-saturated fatty acids (Drosophila melanogaster)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Mus musculus)


name: p-PKR dimer localizes to the nucleus (Mus musculus)


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Sus scrofa)


name: Activated FGFR2 binds PLCG1 (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2


name: H2O + holo-[ACP] = (R)-4'-phosphopantetheine + apo-[ACP] + H(+)


name: BACH1 translocates from the cytosol to the nucleoplasm (Sus scrofa)


name: a plastoquinone + 4 H(+)(out) + 2 reduced [plastocyanin] => a plastoquinol + 2 H(+)(in) + 2 oxidized [plastocyanin]


name: (E)-beta-farnesene + diphosphate => (2Z,6E)-farnesyl diphosphate


name: ARV1 transports CHOL from ER membrane to plasma membrane (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ethanolamine + H(+) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: p-S133 CREB1, MEF2D and SRF  bind the ARC gene (Homo sapiens)


name: H2O + L-prolinamide <=> L-proline + NH4(+)


name: 1,2-dioctanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O => H(+) + octanoate + octanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Homo sapiens)


name: FUNDC1 is phosphorylated by CK2 (Caenorhabditis elegans)


name: CIDEA:CIDEC binds lipid droplets (Canis familiaris)


name: 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine <=> 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + H(+) + UDP


name: Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Schizosaccharomyces pombe)


name: UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Xenopus tropicalis)


name: 4-hydroxybenzoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => benzoate + O2 + reduced [NADPH--hemoprotein reductase]


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Saccharomyces cerevisiae)


name: DHNTP is dephosphorylated by PTPS to PTHP (Rattus norvegicus)


name: Digestion of diacylglycerols by extracellular PTL:colipase (Gallus gallus)


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Homo sapiens)


name: pro-defensin alpha 5 is stored in Paneth cell granules (Homo sapiens)


name: REV1 inserts dCMP opposite to AP sites in DNA (Rattus norvegicus)


name: EXA4 is converted to EXC4 by LTC4S (Sus scrofa)


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Drosophila melanogaster)


name: a ganglioside GT1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GQ1c (d18:1(4E)) + CMP + H(+)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Caenorhabditis elegans)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Rattus norvegicus)


name: 4-hydroxybenzoate + all-trans-octaprenyl diphosphate = 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate


name: USP30 binds ATM dimer:Ub-p-PEX5 (Mus musculus)


name: ATM phosphorylates PIDD1 (Canis familiaris)


name: 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + spheroidene => 2-hydroxyspheroidene + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (3R,4R)-7,2',4'-trihydroxyisoflavanol = (6aR,11aR)-3,9-dihydroxypterocarpan + H2O


name: USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin (Homo sapiens)


name: N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine => (9Z,12Z,15Z)-octadecatrienamide + glyoxylate


name: NPC2 transfers CHOL to NPC1 (Drosophila melanogaster)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + H(+) + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] <=> a 3'-terminal ribonucleotide 3'-(5'-diphosphoguanosine)-RNA + L-histidyl-[RNA ligase]


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-2-acetyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: glutamine + H2O => glutamate + NH4+ [GLS] (Caenorhabditis elegans)


name: Diiodinated tyrosine can be deiodinated (Canis familiaris)


name: 6alpha-hydroxy-28-nortyphasterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 28-nortyphasterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Xenopus tropicalis)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Mus musculus)


name: (S)-malate + succinyl-CoA = (S)-malyl-CoA + succinate


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol = 6-sulfo-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->6)-alpha-D-glucosyl-(1->3)-1-alkyl-2-acylglycerol + adenosine 3',5'-bisphosphate + H(+)


name: Receptor CCR6 binds CCL20 ligand (Sus scrofa)


name: Calcineurin binds NFATC1,2,3 (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Canis familiaris)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: H(+) + N,N-dihydroxy-L-hexahomomethionine => (E)-9-(methylsulfanyl)nonanal oxime + CO2 + H2O


name: 2 Fe(III)-[cytochrome c] + H2O + N2 = 2 Fe(II)-[cytochrome c] + 2 H(+) + nitrous oxide


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Bos taurus)


name: H2O + trimetaphosphate = 2 H(+) + triphosphate


name: Phosphorylated FOXO1A is excluded from the nucleus (Canis familiaris)


name: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal


name: ERBB4s80 binds to SRC (Rattus norvegicus)


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Rattus norvegicus)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Bos taurus)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Danio rerio)


name: SMG6 hydrolyzes mRNA with premature termination codon (Xenopus tropicalis)


name: CYP2E1 monooxygenates APAP to NAPQI (Drosophila melanogaster)


name: L-arginine(in) + L-leucine(out) <=> L-arginine(out) + L-leucine(in)


name: T1R1/T1R3 dimer is the umami taste receptor (Rattus norvegicus)


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Bos taurus)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Bos taurus)


name: ERBB4s80 forms a complex with estrogen receptor ESR1 (Xenopus tropicalis)


name: MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Xenopus tropicalis)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + GDP-beta-L-fucose <=> an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc derivative + GDP + H(+)


name: Collagen type I binds integrin alpha11beta1 (Bos taurus)


name: NAD-dependent protein lipoamidase activity


name: FPGS-2 transforms THF to THFPG (Homo sapiens)


name: Caspase-3 cleaves pro-interleukin-16 (Rattus norvegicus)


name: L-xylose + NADP(+) <=> H(+) + L-xylono-1,4-lactone + NADPH


name: GPI dimer isomerizes Fru(6)P to G6P (Bos taurus)


name: calcitriol + UDP-alpha-D-glucuronate = calcitriol 25-O-(beta-D-glucuronide) + H(+) + UDP


name: geranylhydroquinone + O2 + reduced [NADPH--hemoprotein reductase] = 3''-hydroxygeranylhydroquinone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Drosophila melanogaster)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + ouabagenin => dihydroouabagenin + 2 Fe(III)-[cytochrome c]


name: 3-fumarylpyruvate + H2O <=> fumarate + H(+) + pyruvate


name: P2X7 mediates membrane pores that include pannexin-1 (Canis familiaris)


name: factor XII -> factor XIIa (Rattus norvegicus)


name: 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] => 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (18S)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + O2 => (5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate


name: H(+) + NADPH + O2 + resorcinol = benzene-1,2,4-triol + H2O + NADP(+)


name: CRYM reduces P2C to PPCA (Schizosaccharomyces pombe)


name: L-aspartate(in) + L-glutamate(out) = L-aspartate(out) + L-glutamate(in)


name: [thioredoxin]-disulfide + dUDP + H2O <=> [thioredoxin]-dithiol + UDP


name: 11-cis-retinol + hexadecanoyl-CoA <=> 11-cis-retinyl hexadecanoate + CoA


name: choline(in) + H(+)(in) <=> choline(out) + H(+)(out)


name: (S)-methylmalonyl-CoA + H(+) <=> CO2 + propanoyl-CoA


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Bos taurus)


name: TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)


name: S100A8:S100A9:AA:Ca(2+) binds NOX2 complex (Sus scrofa)


name: Nephrin mediated activation of N-WASP (Sus scrofa)


name: p-T816-PKN2 phosphorylates AKT1 on serine-308 (Drosophila melanogaster)


name: p75NTR ICD signals to NF-kB (Mus musculus)


name: H(+) + O2 + protoviolaceinate => CO2 + H2O + proviolacein


name: D-aspartate + H2O + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate


name: guanosine(1575) in yeast 18S rRNA + S-adenosyl-L-methionine <=> N(7)-methylguanosine(1575) in yeast 18S rRNA + S-adenosyl-L-homocysteine


name: "Acid--amino-acid ligases (peptide synthases)"


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Danio rerio)


name: The PRC1L4 complex binds the UXT gene promoter (Homo sapiens)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Drosophila melanogaster)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Canis familiaris)


name: 3,5-dimethylcyclohexanamine + H2O + NADP(+) = 3,5-dimethylcyclohexanone + H(+) + NADPH + NH4(+)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + GDP-alpha-D-mannose => (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + GDP + H(+)


name: H2O + NAD(+) + nitrous oxide => H(+) + NADH + 2 nitric oxide


name: 2 a 1-acyl-sn-glycero-3-phosphocholine = a 1,2-diacyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: Activation of proMMP9 by proteases (Danio rerio)


name: VIP receptors bind VIP (Xenopus tropicalis)


name: (6R)-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) <=> 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 H(+) + 2 NADPH


name: Recruitment of HDAC1 by p130 (RBL2) (Sus scrofa)


name: MYO9B inactivates RHOA (Xenopus tropicalis)


name: LZTFL1 binds the BBSome and prevents its traffic to the cilium (Homo sapiens)


name: SHC1 binds P-ERBB4 isoform dimers (Drosophila melanogaster)


name: aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine => H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Drosophila melanogaster)


name: USP8 deubiquitinates RNF128 (Mus musculus)


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Mus musculus)


name: Expression of CRYPTOCHROME-2 (Homo sapiens)


name: adenosine 3',5'-bisphosphate(in) + AMP(out) <=> adenosine 3',5'-bisphosphate(out) + AMP(in)


name: (R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = AMP + diphosphate + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA (Canis familiaris)


name: SUMOylation of TOP2A with SUMO1 (Saccharomyces cerevisiae)


name: Dephosphorylation of phospho-Cdh1 (Mus musculus)


name: 2-phenylacetaldehyde + H(+) + NADPH <=> 2-phenylethanol + NADP(+)


name: HTRA2 degrades APP (Amyloid-beta precursor protein) (Homo sapiens)


name: ARL2:GTP bind PDE6D on KRAS4B (Canis familiaris)


name: (R)-prunasin + H2O => D-glucose + mandelonitrile


name: Dimethyl fumarate modifies Cys191 in GSDMD (Gallus gallus)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Danio rerio)


name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Canis familiaris)


name: GHRH receptor binds GHRH (Gallus gallus)


name: a sphingomyelin(in) + ATP + H2O => a sphingomyelin(out) + ADP + H(+) + phosphate


name: SEMA6A binds to PLXNA2 and PLXNA4 (Homo sapiens)


name: SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane (Danio rerio)


name: RABGGTA binds RABGGTB (Dictyostelium discoideum)


name: 2-deoxyecdysone 22-phosphate + H2O = 2-deoxyecdysone + phosphate


name: 5,10-dihydrophenazine + O2 <=> H2O2 + phenazine


name: 2-methylpropanal + CO2 => 3-methyl-2-oxobutanoate + H(+)


name: H2O + O2 + S-sulfanylglutathione => glutathione + 2 H(+) + sulfite


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O => 1-O-alkyl-2-acyl-sn-glycerol + a fatty acid + H(+)


name: ERBB4 ubiquitination by WWP1/ITCH (Danio rerio)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Schizosaccharomyces pombe)


name: PIAS3 SUMOylates MITF with SUMO1 (Xenopus tropicalis)


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Mus musculus)


name: AMP + diphosphate + malonyl-CoA => ATP + CoA + malonate


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Caenorhabditis elegans)


name: ORC1 gene expression is stimulated by E2F1 (Homo sapiens)


name: ING2-bound EP300 acetylates TP53 (Bos taurus)


name: SUMOylation of MDC1 with SUMO1 (Sus scrofa)


name: H2O + thiamine triphosphate <=> H(+) + phosphate + thiamine diphosphate


name: 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)


name: B4GALTs transfer Gal to the keratan chain (Xenopus tropicalis)


name: Interleukin-35 translocates from the ER lumen to the extracellular region (Bos taurus)


name: acetoacetic acid + NADH + H+ <=> beta-hydroxybutyrate + NAD+ (Sus scrofa)


name: Expression of Lipoprotein lipase (LPL) (Homo sapiens)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Gallus gallus)


name: SUMOylation of HDAC1 with SUMO1 (Dictyostelium discoideum)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Drosophila melanogaster)


name: Phosphorylation and activation of PLCG due to FCGR3A effect (Homo sapiens)


name: Abortive Initiation After Second Transition (Canis familiaris)


name: C2CD3 binds the mother centriole (Canis familiaris)


name: NR1H2,3 binds the EEPD1 gene (Homo sapiens)


name: DPAn-6 SPMs translocate from cytosol to extracellular region (Homo sapiens)


name: Association of procollagen type IV (Mus musculus)


name: Cholesta-7,24-dien-3beta-ol is desaturated to form cholesta-5,7,24-trien-3beta-ol (Bos taurus)


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Xenopus tropicalis)


name: a short-chain (3R)-hydroxy fatty acyl-CoA + NAD(+) = a short-chain 3-oxoacyl-CoA + H(+) + NADH


name: USP21 deubiquitinates RIPK1,DDX58 (Sus scrofa)


name: chloride(in) + 2 hydrogencarbonate(out) + Li(+)(out) => chloride(out) + 2 hydrogencarbonate(in) + Li(+)(in)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-dodecanoyl-sn-glycero-3-phosphocholine <=> 1-dodecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: USP30 deubiquitinates Ub-MOM proteins (Homo sapiens)


name: (2E)-geranyl diphosphate + olivetolate <=> cannabigerolate + diphosphate


name: Association of procollagen type III (Homo sapiens)


name: H(+)(in) + phosphate(in) <=> H(+)(out) + phosphate(out)


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Dictyostelium discoideum)


name: CD59 inhibits MAC formation (Bos taurus)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Schizosaccharomyces pombe)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Mus musculus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Xenopus tropicalis)


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Gallus gallus)


name: MTORC1 dissociates from ULK complex (Homo sapiens)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Bos taurus)


name: (S)-cis-N-methylscoulerine + S-adenosyl-L-homocysteine => (S)-scoulerine + S-adenosyl-L-methionine


name: (10bR,4aS)-noroxomaritidine + H(+) + NADPH = (10bR,4aS)-oxomaritidine + NADP(+)


name: (S)-3-hydroxyglutaryl-CoA <=> (2E)-glutaconyl-CoA + H2O


name: 3-hydroxyisoheptadecanoyl-CoA => (2E)-15-methylhexadecenoyl-CoA + H2O


name: TRAF6 oligomer autoubiquitinates (Canis familiaris)


name: COX15 transforms heme O to heme A (Schizosaccharomyces pombe)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Mus musculus)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + H(+) + hexadecanoate


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Gallus gallus)


name: a D-threo-aldono-1,5-lactone + H(+) + NADH => a D-threo-aldose + NAD(+)


name: ATP + streptomycin => 3''-O-adenylylstreptomycin + diphosphate


name: Cross-linking of FCGRIA with IgG-coated Ag (Gallus gallus)


name: H2O + O2 + tyramine = (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+)


name: ethionamide + H(+) + NADPH + O2 <=> ethionamide S-oxide + H2O + NADP(+)


name: 4 Fe(III)-[cytochrome c] + hydrazine => 4 Fe(II)-[cytochrome c] + 4 H(+) + N2


name: (2E,6E)-farnesyl diphosphate => aristolene + diphosphate


name: SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Bos taurus)


name: (R)-carnitine + octanoyl-CoA = CoA + O-octanoyl-(R)-carnitine


name: FMO1:FAD oxidizes HTAU to TAU (Bos taurus)


name: Constitutive phosphorylation by GSK3 (Homo sapiens)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Sus scrofa)


name: 1D-myo-inositol 3-phosphate + ADP + H(+) => ATP + myo-inositol


name: H2O + L-lysine + NAD(+) = (S)-2-amino-6-oxohexanoate + H(+) + NADH + NH4(+)


name: Formation of P-TEFb complex (Drosophila melanogaster)


name: Formation of the Flap Intermediate (Sus scrofa)


name: Factor B binds to C3(H2O) (Xenopus tropicalis)


name: A + clavatol + 3 CO2 + 4 CoA + H2O + 2 S-adenosyl-L-homocysteine => acetyl-CoA + AH2 + H(+) + 3 malonyl-CoA + 2 S-adenosyl-L-methionine


name: STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Sus scrofa)


name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Bos taurus)


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Homo sapiens)


name: NT5E:Zn2+ hydrolyses NMN (Rattus norvegicus)


name: cis-(homo)2aconitate + H2O <=> (2R,3S)-iso(homo)2citrate


name: GPLD1 hydrolyses GPI-anchors from proteins (Dictyostelium discoideum)


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Gallus gallus)


name: choloyl-CoA + glycine <=> CoA + glycocholate + H(+)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Danio rerio)


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Homo sapiens)


name: Association of procollagen type XXVI (Mus musculus)


name: H2O + NADP(+) + staphylopine <=> (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + NADPH + pyruvate


name: Guanine + H2O => Xanthine + NH4+ (Xenopus tropicalis)


name: PINK1 is autophosphorylated (Rattus norvegicus)


name: a fatty acid + sphing-4-enine => an N-acylsphing-4-enine + H2O


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Sus scrofa)


name: 3,4-dihydroxybenzoyl-5'-AMP + diphosphate => 3,4-dihydroxybenzoate + ATP + H(+)


name: H(+) + malonyl-CoA + tetradecanoyl-CoA = 3-oxohexadecanoyl-CoA + CO2 + CoA


name: L-glutamine + scyllo-inosose => 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)


name: CCND1 binds RUNX3 and displaces EP300 (Homo sapiens)


name: Arachidonate is oxidised to PGG2 by PTGS2 (Rattus norvegicus)


name: 8 H(+) + heme b + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> biliverdin IXalpha + CO + Fe(2+) + 3 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: an N(4)-(oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl-[protein] + H2O = an oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-D-GlcNAc + N(4)-(N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein]


name: ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE (Dictyostelium discoideum)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Schizosaccharomyces pombe)


name: tetraketide alpha-pyrone synthase activity


name: O2 + reduced [NADPH--hemoprotein reductase] + secologanin => 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + secoxyloganin


name: hexadecanoyl-CoA + sn-glycerol 3-phosphate = 1-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: D-nopaline + H2O + NADP(+) => 2-oxoglutarate + H(+) + L-arginine + NADPH


name: [DsrC protein]-dithiol + 3 H(+) + NADH + sulfite => [DsrC protein]-trisulfide + 3 H2O + NAD(+)


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Bos taurus)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Plasmodium falciparum)


name: H(+) + hexadecanoate + sn-glycerol 3-phosphocholine => 2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + ATP => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+)


name: cytidine + phosphate => alpha-D-ribose 1-phosphate + cytosine


name: Transport of Antigen peptide in to ER (Rattus norvegicus)


name: M dimer localizes to nucleus (Homo sapiens)


name: SMAC (DIABLO) forms dimer (Homo sapiens)


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Bos taurus)


name: sulfate(in) + sulfite(out) => sulfate(out) + sulfite(in)


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Sus scrofa)


name: SMURF2 monoubiquitinates SMAD3 (Homo sapiens)


name: cyclo[(Z)-alpha,beta-didehydrophenylalanyl-L-leucyl] + O2 => albonoursin + H2O2


name: an acyl-CoA + H(+) + malonyl-[ACP] <=> a 3-oxoacyl-[ACP] + CO2 + CoA


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + phosphate => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + NH4(+)


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Sus scrofa)


name: (1S,3bR,4R,5aR,9aR,9bR,11aS)-1-[(4R)-5-[(2S)-3,3-dimethyloxiran-2-yl]-1,4-dihydroxybutan-2-yl]-3b,6,6,9a,11a-pentamethyl-7-oxo-1H,2H,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-4-yl acetate + O2 + reduced [NADPH--hemoprotein reductase] => (1S,3bR,4R,5aR,9aR,9bR,11aS)-1-(1-hydroxy-4-oxobutan-2-yl)-3b,6,6,9a,11a-pentamethyl-7-oxo-1H,2H,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-4-yl acetate + 2-methylpropanoate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Homo sapiens)


name: AACS ligates CoA-SH to ACA, forming ACA-CoA (Caenorhabditis elegans)


name: (2S)-liquiritigenin + O2 + reduced [NADPH--hemoprotein reductase] <=> 2 H(+) + H2O + licodione + oxidized [NADPH--hemoprotein reductase]


name: Disulfiram covalently modifies Cys191 in GSDMD (Canis familiaris)


name: Phosphorylated PKN1 binds androgen receptor (AR) (Canis familiaris)


name: RAD51B:RAD51C binds single-stranded DNA (Rattus norvegicus)


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Bos taurus)


name: (6R)-10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinose => (6S)-5,6,7,8-tetrahydrofolate + H(+) + UDP-4-deoxy-4-formamido-beta-L-arabinose


name: HMGCR dimer binds statins (Dictyostelium discoideum)


name: CBL dissociates from ubiquitinated p-SPRY2 (Sus scrofa)


name: (R)-4'-phosphopantetheine + apo-[ACP] + H(+) => H2O + holo-[ACP]


name: D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]


name: PAK2 binds NCK (Drosophila melanogaster)


name: RFC dissociates after sliding clamp formation (Mus musculus)


name: Presence of PI(3,5)P2 stimulates the maturation of the early endosome into the late endosome (Homo sapiens)


name: 1-octadecanoyl-2-nonanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + nonanoate


name: PDCL promotes G-protein beta 5 folding (Bos taurus)


name: ADP + arsenate(out) + H(+) + phosphate => arsenate(in) + ATP + H2O


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Sus scrofa)


name: 2,5-diformylfuran + H2O <=> 2-(dihydroxymethyl)-5-formylfuran


name: ACER3 hydrolyzes phytoceramide (Mus musculus)


name: 8-methylquinolin-2(1H)-one + AH2 => 8-methylquinoline + A + H2O


name: acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Homo sapiens)


name: STARD7 transports Q10 to plasma membrane (Sus scrofa)


name: (E)-coniferol + D-glucose => 4-O-(beta-D-glucosyl)-(E)-coniferol + H2O


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Drosophila melanogaster)


name: 2-nitroimidazole + H2O => 1,3-dihydro-2H-imidazol-2-one + H(+) + nitrite


name: (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(out) => (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(in)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Danio rerio)


name: ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Sus scrofa)


name: E2F1, E2F2, or E2F3 and SP1 bind p14ARF promoter (Homo sapiens)


name: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine => (+)-pisatin + H(+) + S-adenosyl-L-homocysteine


name: SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: H(+) + NADPH + O2 + theophylline = 3-methylxanthine + formaldehyde + H2O + NADP(+)


name: Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide (Sus scrofa)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Drosophila melanogaster)


name: Defective SLC36A2 does not cotransport Gly, L-Pro with H+ from extracellular region to cytosol (Homo sapiens)


name: B4GALNT2 transfers GalNAc from UDP-GalNAc to Sial-Gal-GlcNAc-Gal to form the Sd(a) antigen on UMOD (Homo sapiens)


name: 2 cob(II)alamin-[cyanocobalamin reductase] + 2 hydrogen cyanide + NADP(+) <=> 2 apo-[cyanocobalamin reductase] + 2 cyanocob(III)alamin + H(+) + NADPH


name: Dimerization of LIMK1 by Hsp90 (Dictyostelium discoideum)


name: ethylene receptor histidine kinase activity


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + choline <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + ethanolamine


name: 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Caenorhabditis elegans)


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Gallus gallus)


name: C30 botryococcene + S-adenosyl-L-methionine => 20-methyl-21,22-didehydro-20,21-dihydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Xenopus tropicalis)


name: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + O2 => CO2 + formaldehyde + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + succinate


name: ORC6 translocates to the nucleus (Drosophila melanogaster)


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Caenorhabditis elegans)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)


name: H(+)(out) + K(+)(in) + L-glutamate(out) + 3 Na(+)(out) <=> H(+)(in) + K(+)(out) + L-glutamate(in) + 3 Na(+)(in)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate = adenosine 5'-tetraphosphate + AMP + 2 H(+)


name: AKT1S1 (PRAS40) binds mTORC1 (Homo sapiens)


name: a 1,2-diacylglycerol + H2O => a 2-acylglycerol + a carboxylate + H(+)


name: 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + NAD(+) = CO2 + cycloeucalenone + NADH


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Plasmodium falciparum)


name: Phosphorylation of SLP-76 by p-SYK (Sus scrofa)


name: AMP + 2 H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] => (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein]


name: 3'-phosphoadenylyl sulfate + sungeidine F <=> adenosine 3',5'-bisphosphate + H(+) + sulfosungeidine F


name: TTC19 clears UQCRFS1 fragments from Complex III (Sus scrofa)


name: PKA phosphorylates PDE4B (Xenopus tropicalis)


name: ATP + beta-D-galactose(out) + H2O = ADP + beta-D-galactose(in) + H(+) + phosphate


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Homo sapiens)


name: FeHM dissociates from MetHb (Sus scrofa)


name: P2Y9 receptor can bind to LPA (Danio rerio)


name: glutathione + RX = a halide anion + an S-substituted glutathione + H(+)


name: GPIHBP1 binds HSPG:LPL dimer (Canis familiaris)


name: (3R)-3-hydroxy-D-aspartate = glycine + glyoxylate


name: Anti-MET small tyrosine kinase inhibitors bind MET (Caenorhabditis elegans)


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Mus musculus)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Mus musculus)


name: 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Gallus gallus)


name: 2-oxo-dAMP + H(+) + phosphate => 2-oxo-dADP + H2O


name: 3alpha-hydroxy-5beta-pregnan-20-one + NADP(+) <=> 5beta-pregnan-3,20-dione + H(+) + NADPH


name: chrodrimanin A + H2O + NADP(+) => chrodrimanin T + H(+) + NADPH + O2


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Bos taurus)


name: PIP3 recruits PDPK1 to the membrane (Mus musculus)


name: Exocytosis of tertiary granule membrane proteins (Caenorhabditis elegans)


name: 2 ATP + 2 cob(II)inamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)inamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: G alpha (z) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)


name: miR-200c-3p binds CDH11 mRNA (Homo sapiens)


name: (1R)-(2-amino-1-hydroxyethyl)phosphonate + O2 = glycine + 2 H(+) + phosphate


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-pyrethrolone <=> CoA + pyrethrin I


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Gallus gallus)


name: IFNG gene expression is stimulated by RUNX1 and inhibited by FOXP3 (Homo sapiens)


name: RAP1A exchanges GDP for GTP (Rattus norvegicus)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Danio rerio)


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Mus musculus)


name: ATP + carbamoyl phosphate + H2O + tobramycin <=> AMP + diphosphate + H(+) + nebramycin 5' + phosphate


name: SLC6A3 binds DRIs (Drosophila melanogaster)


name: H2O + L-serine + O2 = 3-hydroxypyruvate + H2O2 + NH4(+)


name: 4-methylcyclohexanone + H(+) + NADPH + NH4(+) => 4-methyl-cyclohexylamine + H2O + NADP(+)


name: (2E,6E)-farnesyl diphosphate <=> (E)-beta-farnesene + diphosphate


name: ATP + H2O + L-phenylalanine => AMP + D-phenylalanine + diphosphate + H(+)


name: quercetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose = H(+) + quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP


name: PTGS1,2 dimers bind PTGS Inhibitors (Canis familiaris)


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Caenorhabditis elegans)


name: CO binds to Cytochrome c oxidase (Gallus gallus)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Sus scrofa)


name: (indol-3-yl)acetyl-L-aspartate + H2O = (indol-3-yl)acetate + L-aspartate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CTP <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CDP + H(+)


name: 13-cis-retinol + a fatty acyl-CoA = 13-cis-retinyl ester + CoA


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-epi-alpha-bisabolol + diphosphate


name: Activation of RAC1 by the PXN:CRK complex (Drosophila melanogaster)


name: Oligomerization of p-CARMA1 (Canis familiaris)


name: misfolded CFTR is degraded by the 26S proteasome (Canis familiaris)


name: glycolate + NADP(+) <=> glyoxylate + H(+) + NADPH


name: D-ribulose 5-phosphate <=> ribose 5-phosphate (Saccharomyces cerevisiae)


name: a ribonucleoside 5'-diphosphate + ATP <=> a ribonucleoside 5'-triphosphate + ADP


name: Dissociation of Cdc20 from APC/C complex (Rattus norvegicus)


name: DPP4 binds DPP4 inhibitors (Schizosaccharomyces pombe)


name: aklavinone + dTDP-beta-L-rhodosamine <=> aclacinomycin T + dTDP + 2 H(+)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Canis familiaris)


name: 2-hydroxyspheroidene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2,2-dihydroxyspheroidene + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Homo sapiens)


name: 4-acetoxybenzaldehyde + H(+) + NADH => 4-acetoxybenzyl alcohol + NAD(+)


name: (indol-3-yl)acetate + H(+) + NADH + O2 => 2-hydroxy-(1H-indol-3-yl)acetate + H2O + NAD(+)


name: TET3 binds chromatin with H3K17me2a and 5-mC:METTL23:STGP4 (Homo sapiens)


name: L-alanine + pyridoxal 5'-phosphate => pyridoxamine 5'-phosphate + pyruvate


name: UDP-alpha-D-xylose + zeatin = H(+) + O-beta-D-xylosylzeatin + UDP


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Schizosaccharomyces pombe)


name: Dissociation of the COP1-p53 complex (Rattus norvegicus)


name: H(+) + NADPH + O2 + protodeoxyviolaceinate = H2O + NADP(+) + protoviolaceinate


name: Dissociation of RAS:RAF complex (Rattus norvegicus)


name: 3-dehydro-alpha,alpha-trehalose + H2O => 3-dehydro-D-glucose + D-glucose


name: Axonal transport of NGF:Trk complexes (Canis familiaris)


name: acetyl-CoA + octopamine => CoA + H(+) + N-acetyloctopamine


name: H(+) + NADH + O2 + salicylate => 2,5-dihydroxybenzoate + H2O + NAD(+)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Drosophila melanogaster)


name: 1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-3-acylglycerol + a monoacyl-sn-glycero-3-phosphocholine


name: Spike glycoprotein of SARS-CoV-2 binds ACE2 on host cell (Homo sapiens)


name: Aggrecan binds Hyaluronan and HAPLN1 (Mus musculus)


name: RIP2 induces K63-linked ubiquitination of NEMO (Danio rerio)


name: Binding of NS1 to cleavage and host polyadenylation specificity factor (CPSF) (Homo sapiens)


name: cortisol + NAD(+) <=> cortisone + H(+) + NADH


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate


name: SLC25A12,13 exchange L-Glu and L-Asp (Bos taurus)


name: PSMC4 binds PSMC5 (Drosophila melanogaster)


name: L-tyrosine + NADPH + S-adenosyl-L-methionine <=> 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+)


name: RHOC GEFs activate RHOC (Canis familiaris)


name: MBTPS1 (S1P) cleaves CREB3 (Canis familiaris)


name: CD59 inhibits MAC formation (Sus scrofa)


name: Collagen type XIII binds Integrin alpha1beta1 (Canis familiaris)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Xenopus tropicalis)


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Homo sapiens)


name: PI(3,5)P2 transports from the late endosome membrane to the Golgi membrane (Homo sapiens)


name: PRKCB (PKC-beta) phosphorylates CARMA1 (Gallus gallus)


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Mus musculus)


name: CK2 binds FACT (Drosophila melanogaster)


name: Collagen type VII degradation by MMP1,2,3 (Caenorhabditis elegans)


name: H2O + L-methionyl-S-oxide-[protein] + NADP(+) => H(+) + L-methionyl-[protein] + NADPH + O2


name: Mitochondrial recruitment of Drp1 (Danio rerio)


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Rattus norvegicus)


name: Removal of siRNA passenger strand (Rattus norvegicus)


name: lipid A-core heptosyltransferase activity


name: ARL3:GTP binds the UNC119B complex (Homo sapiens)


name: Furin cleaves pro-GAS6 to GAS6 (Canis familiaris)


name: Defective GYS2 does not transfer glucose to growing glycogen chains (Homo sapiens)


name: Formation of nonameric complex (Xenopus tropicalis)


name: LPA-binding receptors bind LPA (Xenopus tropicalis)


name: TYRP1 oxidises DHICA to IQCA (Canis familiaris)


name: PRKCI phosphorylates ELF3 (Homo sapiens)


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Danio rerio)


name: IQGAP1 binds CLIP1 and microtubules (Dictyostelium discoideum)


name: beta-D-glucose + quercetin => H2O + quercetin 4'-O-beta-D-glucoside


name: (E)-phenylacetaldehyde oxime <=> (Z)-phenylacetaldehyde oxime


name: dodecanoyl-CoA + H(+) + malonyl-[ACP] <=> 3-oxotetradecanoyl-[ACP] + CO2 + CoA


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Canis familiaris)


name: abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Homo sapiens)


name: PREX2 binds PTEN and inhibits it (Mus musculus)


name: GBA3 hydrolyzes GlcCer (cytosol) (Bos taurus)


name: Release of Cytochrome c from mitochondria (Caenorhabditis elegans)


name: STAT1,STAT3,STAT6 phosphorylation (Bos taurus)


name: Interaction of integrin alphaIIbbeta3 with Fibronectin (Mus musculus)


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Danio rerio)


name: Heterodimerization of E proteins with Myod (Homo sapiens)


name: (3S)-3-hydroxy-L-enduracididine + CO2 + succinate => 2-oxoglutarate + L-enduracididine + O2


name: a 5'-end ribonucleotide-tRNA(His) + ATP + H(+) = a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + diphosphate


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Canis familiaris)


name: Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)


name: 4-hydroxy-2-oxoglutarate + L-glutamate => 2-oxoglutarate + 4-hydroxy-L-glutamate


name: H2O + hexadecanedioyl-CoA = CoA + H(+) + hexadecanedioate


name: brain-derived neurotrophic factor receptor binding


name: Activation of Rap1 by cytosolic GEFs (Dictyostelium discoideum)


name: UDP-alpha-D-galacturonate(in) + UMP(out) <=> UDP-alpha-D-galacturonate(out) + UMP(in)


name: 3-[(E)-2-isocyanovinyl]indole + 2 CO2 + H2O + succinate => (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2


name: 5-amino-6-(D-ribitylamino)uracil + glyoxal => 5-(2-oxoethylideneamino)-6-(D-ribitylamino)uracil + H2O


name: Interaction of Plectin with Integrin beta 4 (Canis familiaris)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Schizosaccharomyces pombe)


name: a cytidine in 25S rRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in 25S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 4-nitrobenzaldehyde + H(+) + NADPH => 4-nitrobenzyl alcohol + NADP(+)


name: HTR1 and 5A receptors can bind serotonin (Bos taurus)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 2-acylglycerol <=> a 1-acyl-sn-glycero-3-phosphoethanolamine + a 2,3-diacyl-sn-glycerol


name: 4-chlorobenzoate + H2O <=> 4-hydroxybenzoate + chloride + H(+)


name: H2O + NADH = AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide


name: The Ligand:GPCR:G12/13 complex dissociates (Bos taurus)


name: SIRT1,SIRT3 deacetylate FOXO3 (Gallus gallus)


name: FKBP1A binds sirolimus (Schizosaccharomyces pombe)


name: AMP + H(+) + NADH + phosphate => (6S)-NADHX + ADP


name: ligand-gated monoatomic ion channel activity


name: dimethylallyl diphosphate + verruculogen <=> diphosphate + fumitremorgin A


name: AMP + ATP <=> ADP + ADP [AK2] (Caenorhabditis elegans)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Danio rerio)


name: GSDME (1-270) binds cardiolipin (Canis familiaris)


name: (+)-caryolan-1-ol => (+)-(E)-beta-caryophyllene + H2O


name: (1S,4S)-5-oxo-1,2-campholide <=> [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + H(+)


name: RNA polymerase II C-terminal domain S5 O-GlcNAc transferase activity


name: NPAS4 binds ARNTL (BMAL1) (Canis familiaris)


name: alpha-acoradiene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: Formation of Cyclin E:Cdk2 complexes (Canis familiaris)


name: a quinone + L-proline => (S)-1-pyrroline-5-carboxylate + a quinol + H(+)


name: a 3-oxoacyl-CoA + CO2 + CoA => an acyl-CoA + H(+) + malonyl-CoA


name: Deacetylation of cleaved cohesin (Rattus norvegicus)


name: "receptor protein serine/threonine kinase"


name: Formation of the preholoproteasome (Sus scrofa)


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Drosophila melanogaster)


name: (Z)-3-aminoacrylate + carbamate + H(+) => (Z)-3-ureidoacrylate + H2O


name: a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate = a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate


name: OSM,LIF,CTF1 receptor complex binds gp130 (Rattus norvegicus)


name: H2O + L-seryl-tRNA(Ala) <=> L-serine + tRNA(Ala)


name: DNMT3B:DNMT3L methylates cytosine in DNA (Homo sapiens)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate => benzyl isothiocyanate + sulfate


name: Phosphorylated WTS autophosphorylates (Drosophila melanogaster)


name: Cathelicidin LL-37 binds to bacterial cell wall (Bos taurus)


name: a 2'-deoxyribonucleoside 5'-phosphate + ATP => a 2'-deoxyribonucleoside 5'-diphosphate + ADP


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Canis familiaris)


name: KSRP recruits RNA degradation activities (Mus musculus)


name: Pellino ubiquitinates IRAK1 (Bos taurus)


name: L-ornithine(out) + putrescine(in) <=> L-ornithine(in) + putrescine(out)


name: L-histidine(in) + L-phenylalanine(out) => L-histidine(out) + L-phenylalanine(in)


name: (S)-lactate + 2 H(+) + NADH => (S)-lactaldehyde + H2O + NAD(+)


name: SREBP1A,2 binds the SQLE promoter (Homo sapiens)


name: PDE4A hydrolyses cAMP to AMP (Bos taurus)


name: 2-acyl LPC is acylated to PC by LPCAT (Rattus norvegicus)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O => 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: GTP-binding activates eEF2 (Schizosaccharomyces pombe)


name: H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + acetate


name: 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine <=> 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: 2 3-amino-4-hydroxybenzoate + H(+) + N-acetyl-L-cysteine + 2 O2 = CO2 + grixazone B + 4 H2O


name: 5alpha-pregnane-3,20-dione + NADP(+) = H(+) + NADPH + progesterone


name: PLK1 hyperphosphorylates Condensin II complex (Sus scrofa)


name: (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA + H(+) + NADPH <=> (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + NADP(+)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Canis familiaris)


name: Nectin-1:Nectin-4 trans heterodimer formation (Mus musculus)


name: JMJD6 demethylates MeR3-histone H3 (Caenorhabditis elegans)


name: SLC25A18,22 import L-Glu, H+ (Bos taurus)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Sus scrofa)


name: p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Xenopus tropicalis)


name: SOAT can transport taurolithocholate-3-sulphate (Xenopus tropicalis)


name: bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer (Mus musculus)


name: Translocation of activated BAX to the mitochondria (Homo sapiens)


name: ent-7alpha-hydroxykaur-16-en-19-oate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> gibberellin A12 aldehyde + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: NUDT1 hydrolyses 2-oxo-dATP to 2-oxo-dAMP (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-(2S,3R,9R)-pristinol + diphosphate


name: 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase]


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)


name: PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)


name: NEDD4 ubiquitinates ERBB4jmAcyt1s80 dimer (Homo sapiens)


name: Active FLT3 binds to ABL2 (Canis familiaris)


name: (beta-L-Ara4N)2-(Kdo)2-lipid A(out) + ADP + H(+) + phosphate => (beta-L-Ara4N)2-(Kdo)2-lipid A(in) + ATP + H2O


name: ENGASE hydrolyses unfolded protein:(GlcNAc)2 (Man(9-5) (Dictyostelium discoideum)


name: Autophosphorylation of PAK (Mus musculus)


name: ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA (Bos taurus)


name: PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Canis familiaris)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Mus musculus)


name: polynucleotide adenylyltransferase activator activity


name: ATP + beta-alanine + L-arginine <=> ADP + beta-alanyl-L-arginine + H(+) + phosphate


name: extracellularly ATP-gated monoatomic cation channel activity


name: P2X7 mediates loss of intracellular K+ (Homo sapiens)


name: a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> a 2-methoxy-6-(all-trans-polyprenyl)phenol + H(+) + S-adenosyl-L-homocysteine


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Mus musculus)


name: 2-demethylmenaquinone-8 + H(+) + NADPH <=> 2-demethylmenaquinol-8 + NADP(+)


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Dictyostelium discoideum)


name: Import of PIC to the Host Nucleus (Homo sapiens)


name: 2',3'-cyclophospho-UMP + H2O <=> 3'-UMP + H(+)


name: RAC2 translocates to the phagocytic vesicle membrane (Danio rerio)


name: (R)-2-methylpyrrolidine + NADP(+) <=> 2-methyl-1-pyrroline + H(+) + NADPH


name: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP <=> 8-desmethylnovobiocic acid + AMP + diphosphate


name: Heterodimerization of CEACAMs (Canis familiaris)


name: 3-phenylpropanoate + H(+) + NADH + O2 => 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)


name: dihydrochelirubine + NADP(+) = chelirubine + NADPH


name: PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Gallus gallus)


name: PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Saccharomyces cerevisiae)


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Mus musculus)


name: aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Mus musculus)


name: 4 H(+) + 4 malonyl-CoA = (3,5-dihydroxyphenyl)acetyl-CoA + 4 CO2 + 3 CoA + H2O


name: factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain (Homo sapiens)


name: H2O + limonene 1,2-epoxide + NADP(+) => (4R)-limonene + H(+) + NADPH + O2


name: (E,E)-piperate + ATP + H(+) = (E,E)-piperoyl-AMP + diphosphate


name: CD320-mediated TCN2:RCbl uptake and delivery to lysosome (Mus musculus)


name: a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP(+) = an (R)-2-alkyl-3-oxoalkanoate + H(+) + NADPH


name: 5alpha-cholest-8-en-3beta-ol + NADP(+) <=> H(+) + NADPH + zymosterol


name: 6-amino-6-deoxyfutalosine + H(+) + H2O => futalosine + NH4(+)


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Bos taurus)


name: Alignment Of The RNA Template On The Telomeric Chromosome End (Mus musculus)


name: abieta-7,13-dien-18-al + O2 + reduced [NADPH--hemoprotein reductase] <=> abieta-7,13-dien-18-oate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + CoA


name: EML4 recruits NUDC to mitotic spindle (Bos taurus)


name: all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase] => all-trans-4-hydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 (Homo sapiens)


name: 2xPPCS ligates PPanK with Cys (Saccharomyces cerevisiae)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Canis familiaris)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: (2S)-2-hydroxy-2-(4-methoxyphenyl)acetonitrile => 4-methoxybenzaldehyde + hydrogen cyanide


name: pro-SFTPC translocates from ER membrane to multivesicle body (Sus scrofa)


name: (9Z,12Z,15Z)-octadecatrienoate + ATP + CoA = (9Z,12Z,15Z)-octadecatrienoyl-CoA + AMP + diphosphate


name: CLIP1(1-1083)-LTK(488-864) fusion dimerizes (Homo sapiens)


name: stigmasterol + UDP-alpha-D-glucose <=> H(+) + stigmasteryl 3-beta-D-glucoside + UDP


name: Release Of ADP From Myosin (Canis familiaris)


name: Aquaporins passively transport water into cells (Homo sapiens)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)


name: NADP(+) + nitrite + pentaerythritol trinitrate => NADPH + pentaerythritol tetranitrate


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Canis familiaris)


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: (3R)-3-hydroxybutanoyl-CoA + H2O <=> (R)-3-hydroxybutanoate + CoA + H(+)


name: GST trimers transfer GS from GSH to luminal substrates (Homo sapiens)


name: ISGylation of host protein filamin B (Sus scrofa)


name: (25R)-26-hydroxycholestanol + H2O + 2 oxidized [adrenodoxin] => cholestanol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: 2-epi-5-epi-valiolone 7-phosphate <=> 5-epi-valiolone 7-phosphate


name: alpha-maltotriose + beta-maltose = alpha-maltotetraose + beta-D-glucose


name: N(pros)-phospho-L-histidyl-[protein] + N-acetyl-beta-D-muramate(out) => L-histidyl-[protein] + N-acetyl-beta-D-muramate 6-phosphate(in)


name: CTP + N,N-diacetyllegionaminate <=> CMP-N,N-diacetyllegionaminate + diphosphate


name: CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA => a cardiolipin + CoA


name: L-alanine(out) + L-methionine(in) => L-alanine(in) + L-methionine(out)


name: 3-alpha-D-mannopyranosyl-alpha-D-mannopyranose + UDP-alpha-D-xylose = 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose + H(+) + UMP


name: acetyl-CoA + pyruvate => (3R)-citramalyl-CoA


name: sulfathiazole transmembrane transporter activity


name: USP12, USP26 deubiquitinate AR (Canis familiaris)


name: HDAC10 deacetylates histone (Saccharomyces cerevisiae)


name: NADP(+) + ursocholate => 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADPH


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Schizosaccharomyces pombe)


name: PP2A dephosphorylates serine-127 of YAP1 (Rattus norvegicus)


name: a fatty acid + acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) => 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O


name: (R)-adrenaline(in) + 2 H(+)(out) = (R)-adrenaline(out) + 2 H(+)(in)


name: LONP1 degrades mitochondrial matrix proteins (Mus musculus)


name: GPR31 is a receptor for 12(S)-HETE (Mus musculus)


name: 2-oxoglutaramate + L-alanine => L-glutamine + pyruvate


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]3 + H(+) + H2O => Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + N-(2,3-dihydroxybenzoyl)-L-serine


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Rattus norvegicus)


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Canis familiaris)


name: ABL1 phosphorylates RAD52 (Xenopus tropicalis)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Mus musculus)


name: (-)-cyatha-3,12-diene + O2 + reduced [NADPH--hemoprotein reductase] => erinacol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: minor groove of adenine-thymine-rich DNA binding


name: Caspase-mediated cleavage of Etk (Sus scrofa)


name: a bacteriochlorophyllide d + H2O + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + a bacteriochlorophyllide f + 2 H(+) + 2 L-methionine


name: nitrite efflux transmembrane transporter activity


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)


name: n chloride(in) + urate(out) <=> n chloride(out) + urate(in)


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Canis familiaris)


name: Phosphorylation of PIP2 to PIP3 by PI3K (Sus scrofa)


name: AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Rattus norvegicus)


name: p62 binds ubiquitinated mitochondrial substrates (Homo sapiens)


name: SYK binds to p-Y65,Y76-FCER1G (Bos taurus)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Bos taurus)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Sus scrofa)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 binds PI3K regulatory subunits (Homo sapiens)


name: ATP-activated inward rectifier potassium channel activity


name: Activating ABCC8 mutants cause hyperglycemia in permanent neonatal diabetes mellitus (PNDM) and transient neonatal DM (TNDM) (Homo sapiens)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[protein] => acetyl-CoA + N-terminal L-seryl-[protein]


name: L-cysteine + L-histidine + O2 => H2O + L-alanin-3-yl L-histidin-5-yl sulfoxide


name: ent-kaur-16-en-19-ol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => ent-kaur-16-en-19-al + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: cholesterol + PAPS => cholesterol sulfate + PAP (Xenopus tropicalis)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O <=> (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: OCT3 mediates renal uptake of organic cations (Rattus norvegicus)


name: (4S,5R)-4,5,6-trihydroxy-2-iminohexanoate + H2O <=> 2-dehydro-3-deoxy-D-gluconate + NH4(+)


name: Activated FGFR1 phosphorylates FRS3 (Mus musculus)


name: ATP + H(+) + NADPH + nonanoate = AMP + diphosphate + NADP(+) + nonanal


name: GTP:coenzyme F420 guanyltransferase activity


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Bos taurus)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Sus scrofa)


name: gastric inhibitory peptide receptor activity


name: 3-aminopropanal + L-alanine => propane-1,3-diamine + pyruvate


name: FMO1:FAD oxidizes HTAU to TAU (Xenopus tropicalis)


name: (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + NADH => (2S,3R)-2-hydroxy-3-(indol-3-yl)butanoate + NAD(+)


name: emodin + S-adenosyl-L-methionine => H(+) + questin + S-adenosyl-L-homocysteine


name: D-histidine + H2O + O2 => 3-(imidazol-5-yl)pyruvate + H2O2 + NH4(+)


name: an N-acylneuraminate + CMP + H(+) => a CMP-N-acyl-beta-neuraminate + H2O


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Gallus gallus)


name: 4 H2O + O2 + 4 sulfur <=> 6 H(+) + 2 hydrogen sulfide + 2 sulfite


name: 2-oxoglutarate + gibberellin A44 + O2 => CO2 + gibberellin A19 + H2O + succinate


name: 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate => 10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate


name: acetaldehyde + H(+) + pyruvate = acetoin + CO2


name: (2S)-2-hydroxyphytanate + O2 <=> 2-oxophytanate + H2O2


name: KIAA0101 double monoubiquitination (Mus musculus)


name: benzoyl-CoA + glycine => benzoyl glycine (hippuric acid) + Coenzyme A (Mus musculus)


name: a sphingomyelin + H2O => an N-acylsphing-4-enine 1-phosphate + choline + H(+)


name: 4,8-dihydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase] <=> 4,5,8-trihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Phosphorylated DL/DIF dimer activates transcription (Drosophila melanogaster)


name: CDSN binds the cornified envelope (Homo sapiens)


name: 1-pyrroline-2-carboxylate + AH2 => A + D-proline


name: Disassociation of CLIP from MHC II (Sus scrofa)


name: Defective UNC93B1 does not bind TLR3 (Homo sapiens)


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Caenorhabditis elegans)


name: ent-copalyl diphosphate => diphosphate + ent-sandaracopimara-8(14),15-diene


name: acetyl-CoA + an aliphatic alcohol = an acetyl ester + CoA


name: D-erythronate + NAD(+) = 2-dehydro-D-erythronate + H(+) + NADH


name: WNT ligands traffic to the Golgi (Bos taurus)


name: 2-(N(omega)-L-arginino)succinate <=> fumarate + L-arginine


name: RNF20:RNF40 monoubiquitinates Histone H2B (Mus musculus)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] => (9R)-hydroxy-(10E,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Bos taurus)


name: aklavinone + dTDP-beta-L-rhodosamine => aclacinomycin T + dTDP + 2 H(+)


name: rebaudioside A + UDP => rebaudioside B + UDP-alpha-D-glucose


name: CQ, HCQ are protonated to CQ2+, HCQ2+ (Homo sapiens)


name: SLC2A9 transports Fru, Glc, urate (Homo sapiens)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Rattus norvegicus)


name: DENND5A,B exchange GTP for GDP on RAB39 (Homo sapiens)


name: CIDEC gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Mus musculus)


name: ADP + D-ribose(in) + H(+) + phosphate => ATP + D-ribose(out) + H2O


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NAD(+) = CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADH


name: (S)-malate + 1-O-(trans-sinapoyl)-beta-D-glucose <=> D-glucose + sinapoyl (S)-malate


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Drosophila melanogaster)


name: an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+)


name: (2E)-octadecenoyl-CoA + H2O => 3-hydroxyoctadecanoyl-CoA


name: 5,10-methylenetetrahydromethanopterin + glycine + H2O => 5,6,7,8-tetrahydromethanopterin + L-serine


name: 2 cob(II)alamin-[methionine synthase] + NADPH + 2 S-adenosyl-L-methionine => H(+) + 2 methylcob(III)alamin-[methionine synthase] + NADP(+) + 2 S-adenosyl-L-homocysteine


name: 15-hydroxypentadecanoyl-CoA + AMP + diphosphate => 15-hydroxypentadecanoate + ATP + CoA


name: DAG is metabolized by DAGL to 2-AG (Dictyostelium discoideum)


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Bos taurus)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Bos taurus)


name: (2E)-butenoyl-[ACP] + AMP + H(+) => (2E)-but-2-enoyl-AMP + holo-[ACP]


name: 2-deoxy-D-glucose + ATP => 2-deoxy-D-glucose 6-phosphate + ADP + H(+)


name: RRAGC,D hydrolyzes GTP (Xenopus tropicalis)


name: 4-hydroxy-L-proline(in) + H(+)(in) => 4-hydroxy-L-proline(out) + H(+)(out)


name: acetyl-CoA + ethanol => CoA + ethyl acetate


name: pyrimidine nucleotide transmembrane transporter activity


name: PTK6 phosphorylates BCAR1 (Homo sapiens)


name: 3-hydroxypyruvate + H(+) => CO2 + glycolaldehyde


name: H2O + psi-UMP => D-ribose 5-phosphate + uracil


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)


name: 2-methylbutan-1-ol + acetyl-CoA = 2-methylbutyl acetate + CoA


name: WWTR1 (TAZ) binds ZO-2 (TJP2) (Caenorhabditis elegans)


name: glutathione specific gamma-glutamylcyclotransferase activity


name: (S)-2-hydroxyoctadecanoate + NAD(+) = 2-oxooctadecanoate + H(+) + NADH


name: a medium chain fatty acid + ATP + holo-[ACP] => a medium-chain fatty acyl-[ACP] + AMP + diphosphate


name: Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm (Canis familiaris)


name: 2 glutathione + H(+) + methylarsonate => glutathione disulfide + H2O + methylarsonous acid


name: Formation of hydroxylysyl-pyrrole cross-links (Homo sapiens)


name: BESTs transport cytosolic Cl- to extracellular region (Canis familiaris)


name: Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: USP7 deubiquitinates TP53 and counteracts MDM2 (Canis familiaris)


name: GPI dimer isomerizes Fru(6)P to G6P (Saccharomyces cerevisiae)


name: 2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate = 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: (Z)-glucotropeolin + H2O = (Z)-phenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Canis familiaris)


name: IKKbeta phosphorylates IkB causing NF-kB to dissociate (Bos taurus)


name: vWF binds to collagen (Canis familiaris)


name: p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Sus scrofa)


name: structural constituent of vitelline membrane


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate


name: p-S295-PDE3B hydrolyses cAMP to AMP (Mus musculus)


name: 3-phosphoglycerate + ATP <=> 1,3-bisphosphoglycerate + ADP (Gallus gallus)


name: 26-oxolanosterol + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 26-hydroxylanosterol + O2 + reduced [NADPH--hemoprotein reductase]


name: a ganglioside GT1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b (d18:1(4E)) + CMP + H(+)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Sus scrofa)


name: 3-methyl-2-oxobutanoate(in) + H(+)(in) => 3-methyl-2-oxobutanoate(out) + H(+)(out)


name: Activated MET recruits GRB2-1:SOS1 (Gallus gallus)


name: nicotinate-adenine dinucleotide phosphate => 2'-phospho-cyclic ADP-ribose + nicotinate


name: NEIL1 translocates to the nucleus (Rattus norvegicus)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Bos taurus)


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Mus musculus)


name: (9Z,12Z)-octadecadienoate + O2 = 9-hydroperoxy-(10E,12Z)-octadecadienoate


name: 5-hydroxymethylfurfural + O2 <=> 2,5-diformylfuran + H2O2


name: Active ALK phosphorylates IRS1 (Sus scrofa)


name: ATP + dodecanoate + H(+) => diphosphate + dodecanoyl-AMP


name: (4S)-limonene + H(+) + NADH + O2 => H2O + limonene 1,2-epoxide + NAD(+)


name: a carboxylate + D-aspartate => an N-acyl-D-aspartate + H2O


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Nascent MT-CO1 binds to MITRAC, Mg2+, PE, CL (Sus scrofa)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Rattus norvegicus)


name: Association of Ran-GTP with importin-beta (Homo sapiens)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: Activation of Edited Kainate receptors (Mus musculus)


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Mus musculus)


name: (9Z,12Z)-octadecadienoate + ATP + CoA <=> (9Z,12Z)-octadecadienoyl-CoA + AMP + diphosphate


name: RHOA GAPs stimulate RHOA GTPase activity (Xenopus tropicalis)


name: Dimerized phospho-IRF3 migrates to the nucleus (Sus scrofa)


name: CoA + H(+) + hexacosanoate => H2O + hexacosanoyl-CoA


name: BTK in active Gq-BTK complex is activated (Gallus gallus)


name: all-trans-retinol + NADP(+) <=> all-trans-retinal + H(+) + NADPH


name: Formation of the complex of PSMD3, PSMD6, and SEM1 (Homo sapiens)


name: 2 7-demethylsiderin + NADPH + O2 = desertorin A + 2 H2O + NADP(+)


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Mus musculus)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Sus scrofa)


name: tetrachloroethene reductive dehalogenase activity


name: Phosphorylation of STATs (Rattus norvegicus)


name: butanoyl-CoA + H(+) + NADH => butanal + CoA + NAD(+)


name: Inactivation of Myt1 kinase (Homo sapiens)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (prothrombinase catalyst) (Homo sapiens)


name: alpha-D-ribose 1,5-bisphosphate + ATP <=> 5-phospho-alpha-D-ribose 1-diphosphate + ADP


name: ATP + holo-[BtrI ACP] + L-glutamate => ADP + gamma-L-glutamyl-[BtrI ACP] + phosphate


name: H2O + pristanoyl-CoA <=> 2,6,10,14-tetramethylpentadecanoate + CoA + H(+)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Homo sapiens)


name: RAR:RXR binds SUMO-CRABP2:atRA (Bos taurus)


name: Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-homocysteine => Mg-protoporphyrin IX + S-adenosyl-L-methionine


name: MAOA:FAD oxidatively deaminates of 5HT (Canis familiaris)


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 3 H(+) + 4 S-adenosyl-L-homocysteine


name: (E)-isoeugenol + acetate + NADP(+) => (E)-coniferyl acetate + NADPH


name: CD151 interacts with BP180 and the integrin alpha 6 subunit (Homo sapiens)


name: hexanoyl-CoA + L-seryl-[protein] = CoA + O-hexanoyl-L-seryl-[protein]


name: apo-[aryl-carrier protein] + CoA => adenosine 3',5'-bisphosphate + H(+) + holo-[aryl-carrier protein]


name: 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H2O <=> alpha-D-glucose 1-phosphate + alpha-D-mannose derivative + H(+)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate + 5-methylaminomethyl-2-thiouridine(34) in tRNA + H(+) + H2O + selenophosphate <=> (2E)-thiogeraniol + 5-methylaminomethyl-2-selenouridine(34) in tRNA + diphosphate + phosphate


name: a ribonucleoside 5'-triphosphate + pyruvate <=> a ribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate


name: Active FLT3 phosphorylates CDKN1B (Sus scrofa)


name: all-trans-antheraxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> all-trans-violaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 O2 => 2 CO2 + 2 formaldehyde + L-lysyl(36)-[histone H3] + 2 succinate


name: ethyl (9Z)-octadecenoate + H2O = (9Z)-octadecenoate + ethanol + H(+)


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Bos taurus)


name: Elongation Of The Telomeric Chromosome End (Bos taurus)


name: 4 H(+) + 4 nitrite => 2 H2O + 4 nitric oxide + O2


name: α1-antagonists bind ADRA1A,B,D (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 1,2-diacyl-sn-glycerol + H(+) + phosphoethanolamine


name: arsenate + mycothiol <=> arseno-mycothiol + H2O


name: NEDD4L binds phosphorylated linker region of SMAD2/3 (Sus scrofa)


name: glycocholate + NAD(+) = 7-oxo-glycodeoxycholate + H(+) + NADH


name: Phosphorylated MAPKs phosphorylate ATF-2 (Drosophila melanogaster)


name: L-tyrosine + S-adenosyl-L-methionine <=> 3-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: CYP24A1 hydroxylates 1,25(OH)2D, inactivating it (Rattus norvegicus)


name: ADP + H(+) + Mn(2+)(out) + phosphate => ATP + H2O + Mn(2+)(in)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Plasmodium falciparum)


name: single-stranded DNA endodeoxyribonuclease activity


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Mus musculus)


name: MET dimers autophosphorylate (Xenopus tropicalis)


name: CO2 + NADH + pyruvate => (R)-malate + NAD(+)


name: Defective SLC6A18 does not transport Gly from extracellular region to cytosol (Homo sapiens)


name: (+)-pinoresinol + H(+) + NADPH => (+)-lariciresinol + NADP(+)


name: FLT3 ITD mutants bind STAT5 through GAB2:PTPN11 (Homo sapiens)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Sus scrofa)


name: 2-phenylacetaldehyde + H(+) + NADH <=> 2-phenylethanol + NAD(+)


name: 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> 9beta-pimara-7,15-dien-19-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CDC42 and PIP2 bind WASL, activating it (Homo sapiens)


name: EFNB:GRB4 binds GIT1 (Caenorhabditis elegans)


name: L-threo-3-phenylserine = 3-phenylpyruvate + NH4(+)


name: steviolbioside glucosyltransferase activity (stevioside forming)


name: QPRT transfers PRIB to QUIN to form NAMN (Bos taurus)


name: Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Rattus norvegicus)


name: Fibrillin-1 binds latent TGF-beta (Rattus norvegicus)


name: AMOT proteins bind WWTR1 (TAZ) (Bos taurus)


name: 2-(prostaglandin E2)-sn-glycero-3-phosphoethanolamine + H2O <=> H(+) + prostaglandin E2 + sn-glycero-3-phosphoethanolamine


name: SLC35D2 exchanges UDP-D-glucose for UMP (Rattus norvegicus)


name: 3-oxosphinganine + octanoyl-CoA = CoA + H(+) + N-octanoyl-3-oxosphinganine


name: NF1 is degraded by the proteasome (Dictyostelium discoideum)


name: H(+) + oxidized [electron-transfer flavoprotein] + pentadecanoyl-CoA = (2E)-pentadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 12-oxo-(5S)-hydroxy-(6Z,8E,14Z)-eicosatrienoate + NAD(+) => 12-oxo-leukotriene B4 + H(+) + NADH


name: L1 binds to AP-2 Clathrin complex (Xenopus tropicalis)


name: 2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) => a cardiolipin + glycerol


name: BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Canis familiaris)


name: GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Rattus norvegicus)


name: anthranilate + ATP + H(+) <=> 2-aminobenzoyl-AMP + diphosphate


name: arsenate reductase (thioredoxin) activity


name: a 1,2-diacyl-sn-glycerol + H(+) + O-phospho-L-serine => a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Drosophila melanogaster)


name: Delta(9)-tetrahydrocannabinolate + H(+) => CO2 + Delta(9)-tetrahydrocannabinol


name: H2O + indole-3-acetamide => (indol-3-yl)acetate + NH4(+)


name: RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Gallus gallus)


name: pUb_TRAF6 pIRAK2 recruits TAK1 kinase complex  (Gallus gallus)


name: Activated PLC gamma dissociates from the PDGF receptor (Mus musculus)


name: 3-hydroxypyruvate + H2O2 + NH4(+) => D-serine + H2O + O2


name: (E)-5-hydroxyferulate + S-adenosyl-L-methionine = (E)-sinapate + H(+) + S-adenosyl-L-homocysteine


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Dictyostelium discoideum)


name: H2O + nigerose => alpha-D-glucose + D-glucose


name: (E)-(indol-3-yl)acetaldehyde oxime + CO2 + H2O => H(+) + N,N-dihydroxy-L-tryptophan


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Bos taurus)


name: SGMS1 transfers phosphocholine onto ceramide (Rattus norvegicus)


name: (R)-pantoate + NAD(+) = 2-dehydropantoate + H(+) + NADH


name: (R)-2-hydroxy-fatty acid dehydrogenase activity


name: 5'-deoxyadenosine + [mycofactocin precursor peptide]-C-terminal glycyl-N-{5-[(4-hydroxyphenyl)methyl]-4,4-dimethyl-2-oxopyrrolidin-3-yl}acetamide + A + H(+) + L-methionine => [mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + AH2 + S-adenosyl-L-methionine


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Homo sapiens)


name: MICAL1 produces NADP+, H2O2 (Caenorhabditis elegans)


name: CDK1 phosphorylates NUP98 (Homo sapiens)


name: 1-acyl LPE is acylated to PE by LPEAT (Sus scrofa)


name: 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + H(+) + succinate + sulfite


name: Factor IIa inhibitors (compounds) binds IIa (Rattus norvegicus)


name: H(+) + L-glutaminyl-tRNA(Gln) + phosphate => 5-phosphooxy-L-glutamyl-tRNA(Gln) + NH4(+)


name: AH2 + L-arginyl-[methyl-coenzyme M reductase] + 2 S-adenosyl-L-methionine => (5S)-C-methyl-L-arginyl-[methyl-coenzyme M reductase] + 5'-deoxyadenosine + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: 3'-phosphoadenylyl sulfate + sungeidine F = adenosine 3',5'-bisphosphate + H(+) + sulfosungeidine F


name: Transphosphorylation of pLIMK1 (Bos taurus)


name: Na+/H+ exchanger transport (at cell membrane) (Gallus gallus)


name: D-sorbitol + NADP(+) = H(+) + keto-L-sorbose + NADPH


name: 2 (S)-lactate(in) + prostaglandin H2(out) = 2 (S)-lactate(out) + prostaglandin H2(in)


name: CoA + H(+) + N-acylhexadecasphinganine => a fatty acyl-CoA + hexadecasphinganine


name: SORD oxidizes D-sorbitol to Fru (Homo sapiens)


name: D-cellobiose + H2O => beta-D-glucose + D-glucose


name: a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP => a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP


name: H2O + O2 + pyridoxamine = H2O2 + NH4(+) + pyridoxal


name: Formation of the CTF18-RFC(7s) complex (Gallus gallus)


name: HNF1A-dependent synthesis of GLUT2 protein (Homo sapiens)


name: 4-coumaroyl-CoA + S-adenosyl-L-methionine => CoA + H(+) + N-(4-coumaroyl)-L-homoserine lactone + S-methyl-5'-thioadenosine


name: acetyl-CoA + spermidine = CoA + H(+) + N(8)-acetylspermidine


name: diphosphate + sn-3-(O-farnesylgeranyl)glycerol 1-phosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + sn-glycerol 1-phosphate


name: L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Danio rerio)


name: L-arginyl-tRNA(Arg) + L-leucyl-tRNA(Leu) => cyclo(L-arginyl-L-leucyl) + 2 H(+) + tRNA(Arg) + tRNA(Leu)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Caenorhabditis elegans)


name: 3-methylundecanoyl-CoA + AMP + diphosphate => 3-methylundecanoate + ATP + CoA


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Danio rerio)


name: L-serine + NADP(+) => aminoacetaldehyde + CO2 + NADPH


name: ATP + D-fructose(out) + H2O => ADP + D-fructose(in) + H(+) + phosphate


name: ATP + coproporphyrinogen III(in) + H2O <=> ADP + coproporphyrinogen III(out) + H(+) + phosphate


name: L-glutamine(out) + L-serine(in) + Na(+)(out) <=> L-glutamine(in) + L-serine(out) + Na(+)(in)


name: 2-dehydro-3-deoxy-L-arabinonate = glycolaldehyde + pyruvate


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Homo sapiens)


name: 2,5-dioxovalerate dehydrogenase (NAD+) activity


name: NCOA2(869-1464) binds KAT6A(1-1118) (Homo sapiens)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O => a 2-acyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Xenopus tropicalis)


name: GIP receptor binds gastric inhibitory peptide (Canis familiaris)


name: Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin


name: L-lysyl-[protein] + succinyl-CoA = CoA + H(+) + N(6)-succinyl-L-lysyl-[protein]


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Gallus gallus)


name: (6R)-5,10-methenyltetrahydrofolate + H2O + N(1)-(5-phospho-beta-D-ribosyl)glycinamide <=> (6S)-5,6,7,8-tetrahydrofolate + 2 H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide


name: holo-[CmaD peptidyl-carrier protein] + L-alloisoleucyl-[CmaA peptidyl-carrier protein] => holo-[CmaA peptidyl-carrier protein] + L-alloisoleucyl-[CmaD peptidyl-carrier protein]


name: ATP + H2O <=> adenine + D-ribose 5-triphosphate


name: 2',2'-dihydroxy-2-oxospirilloxanthin = 2,2'-dioxospirilloxanthin + H2O


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Rattus norvegicus)


name: H(+) + N,N-dihydroxy-L-pentahomomethionine <=> (E)-8-(methylsulfanyl)octanal oxime + CO2 + H2O


name: TOPORS SUMOylates SIN3A with SUMO1 (Xenopus tropicalis)


name: ABCC4 accumulation of dense granule contents (Drosophila melanogaster)


name: 12 H(+) + 6 malonyl-CoA + NADH + 5 NADPH = (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + 6 CO2 + 6 CoA + 4 H2O + NAD(+) + 5 NADP(+)


name: 2,4-dihydroxybenzoate + H(+) = CO2 + resorcinol


name: GTP = cyclic pyranopterin phosphate + diphosphate


name: NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Caenorhabditis elegans)


name: Addition of GlcNAc to the glycan on the A arm (Dictyostelium discoideum)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Mus musculus)


name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Rattus norvegicus)


name: 2-phenylethylamine + acetate => H2O + N-(2-phenylethyl)acetamide


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Mus musculus)


name: Arachidonate is oxidised to 5S-HpETE by ALOX5 (Canis familiaris)


name: S-adenosyl-L-methionine + xanthohumol = 4-O-methylxanthohumol + H(+) + S-adenosyl-L-homocysteine


name: 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose => 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+)


name: cAMP activates EPAC1 (Rattus norvegicus)


name: indole-3-ethanol + NAD(+) = H(+) + indole-3-acetaldehyde + NADH


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Canis familiaris)


name: Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Rattus norvegicus)


name: (R)-salsolinol-1-carboxylate + H2O => dopamine + pyruvate


name: (2S)-2-phospholactate + GTP + H(+) => (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate


name: Beta-catenin recruits CDC73 and LEO1 (Sus scrofa)


name: NTPDase1 hydrolyzes nucleoside triphosphates (Rattus norvegicus)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Rattus norvegicus)


name: Caspase-mediated cleavage of occludin (Xenopus tropicalis)


name: G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential


name: RHOC GAPs stimulate RHOC GTPase activity (Schizosaccharomyces pombe)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Gallus gallus)


name: APC/C:Cdh1 polyubiquitinates SKP2 (Bos taurus)


name: (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O <=> (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA


name: Inner coat assembly and cargo binding (Schizosaccharomyces pombe)


name: BRD7 binds TP53 and EP300 (Homo sapiens)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: PIP3:BTK:G beta-gamma complex dissociates to Active BTK, PIP3 and G beta-gamma complex (Homo sapiens)


name: ACSF2 ligates CoA-SH to MCFA (Mus musculus)


name: (R)-adrenaline + H(+) + S-adenosyl-L-homocysteine => (R)-noradrenaline + S-adenosyl-L-methionine


name: Phosphorylation of PKC-theta (Homo sapiens)


name: 6-phospho-D-gluconate + NAD(+) => CO2 + D-ribulose 5-phosphate + NADH


name: Recruitment of PI3K to plasma membrane (Canis familiaris)


name: K+-independent Li+/Ca2+ exchanger transport (Canis familiaris)


name: Furin cleaves pro-prothrombin to prothrombin (Sus scrofa)


name: Binding of TFIIIA To type 1 Promoter (Canis familiaris)


name: Activation of proMMP9 by proteases (Sus scrofa)


name: Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)


name: 3-cyano-L-alanine + 2 H2O = L-aspartate + NH4(+)


name: 2 Fe(III)-[cytochrome c] + L-cysteinyl-[SoxY protein] + thiosulfate = 2 Fe(II)-[cytochrome c] + 2 H(+) + S-sulfosulfanyl-L-cysteinyl-[SoxY protein]


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Danio rerio)


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + L-glutamate => 2-oxoglutarate + [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate


name: WNT5A:FZD4 is endocytosed (Homo sapiens)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Bos taurus)


name: ESTG binds ESR1:chaperone complex (Danio rerio)


name: acetyl-CoA + L-lysyl-[alpha-tubulin] <=> CoA + H(+) + N(6)-acetyl-L-lysyl-[alpha-tubulin]


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Rattus norvegicus)


name: NAGLU hydrolyses Heparan sulfate chain(4) (Canis familiaris)


name: PDCL promotes G-protein beta 5 folding (Rattus norvegicus)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)


name: (2S)-3-sulfolactate + NAD(+) = 3-sulfopyruvate + H(+) + NADH


name: Phosphorylation of PKC-theta (Rattus norvegicus)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine


name: ATP + H2O + L-alanyl-L-histidine(out) <=> ADP + H(+) + L-alanyl-L-histidine(in) + phosphate


name: 2-dehydro-D-glucose + H2O2 + L-phenylalanine => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2


name: 8-chloroquinoline + A + H2O => 8-chloroquinolin-2(1H)-one + AH2


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Canis familiaris)


name: carboxymethoxysuccinate => fumarate + glycolate


name: AOC3 deaminates BZAM (Xenopus tropicalis)


name: O2 + parthenolide + reduced [NADPH--hemoprotein reductase] = 3beta-hydroxyparthenolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cGMP is degraded by PDEs (Gallus gallus)


name: Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Gallus gallus)


name: 6-deoxo-28-nortyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 28-nortyphasterol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: (3R)-hydroxyhexadecanedioyl-CoA + NAD(+) <=> 3-oxohexadecanedioyl-CoA + H(+) + NADH


name: carnosine(in) + n H(+)(in) => carnosine(out) + n H(+)(out)


name: Sulfate is exported to the cytosol in exchange for dicarboxylate (Caenorhabditis elegans)


name: Defective ALG8 does not add glucose to the N-glycan precursor (Homo sapiens)


name: MRN complex binds shortened telomeres (Canis familiaris)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Mus musculus)


name: a quinone + H2O + selenite => a quinol + selenate


name: ISGylation of E2 conjugating enzymes (Homo sapiens)


name: 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 3beta-hydroxy-5alpha-androstan-17-one + O2 + reduced [NADPH--hemoprotein reductase]


name: 2-oxobutanoate + L-alanine <=> (2S)-2-aminobutanoate + pyruvate


name: PCK2 phosphorylates OA to yield PEP (Dictyostelium discoideum)


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate


name: P4HB binds Collagen chains (Drosophila melanogaster)


name: 2-oxoglutarate + L-arginyl-[protein] + O2 => (3R)-3-hydroxy-L-arginyl-[protein] + CO2 + succinate


name: arginine + H2O => ornithine + urea [ARG2] (Bos taurus)


name: PARP1 binds SMAD2/3:SMAD4 heterotrimer (Homo sapiens)


name: L-homocysteine + S-adenosyl-L-methionine = H(+) + L-methionine + S-adenosyl-L-homocysteine


name: Fe3+ dissociates from SLC22A17:LCN2:2,5DHBA (Drosophila melanogaster)


name: butyl 3-(methylsulfanyl)propanoate + CoA => 3-(methylsulfanyl)propanoyl-CoA + butan-1-ol


name: H2O + N-tetradecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-tetradecanoylethanolamine


name: CHL1 interacts with contactin-6 (Homo sapiens)


name: p-T,Y MAPK dimers translocate to nucleus (Danio rerio)


name: RHOD binds effectors at the plasma membrane (Sus scrofa)


name: a quaternary ammonium(out) + ATP + H2O <=> a quaternary ammonium(in) + ADP + H(+) + phosphate


name: Intermediate 1 binds HP subcomplex to form Intermediate 2 (Mus musculus)


name: (R)-S-adenosyl-L-methionine + H2O = adenosine + H(+) + L-methionine


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Homo sapiens)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: C3d-complexed antigen binds to complement receptor (Mus musculus)


name: hyocholate + UDP-alpha-D-glucuronate <=> hyocholoyl-24-O-(beta-D-glucuronate) + UDP


name: BTG2 binds CCR4-NOT complex (Dictyostelium discoideum)


name: CDC42 GAPs stimulate CDC42 GTPase activity (Mus musculus)


name: 2Fe-2S is inserted in UQCRFS1 (Schizosaccharomyces pombe)


name: a ganglioside GA2 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GM2 (d18:1(4E)) + H2O


name: DNA-PKcs autophosphorylates (Gallus gallus)


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Mus musculus)


name: LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Homo sapiens)


name: Exportin complex translocates pre-miRNA to cytosol (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoylglycerol <=> 1-(9Z-octadecenoyl)-3-hexadecanoylglycerol + CoA


name: a cytidine in RNA + S-adenosyl-L-methionine <=> an N(3)-methylcytidine in RNA + H(+) + S-adenosyl-L-homocysteine


name: (Kdo)2-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + di-trans,octa-cis-undecaprenyl diphosphate


name: p-3Y-SHC1 dissociates from IGF1R (Gallus gallus)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Rattus norvegicus)


name: MDM2 translocates to the cytosol (Homo sapiens)


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Caenorhabditis elegans)


name: ATPase activity, coupled to transmembrane movement of ions, rotational mechanism


name: AFG3L2 degrades mitochondrial matrix proteins (Drosophila melanogaster)


name: MECP2 binds the PTPN4 gene promoter (Homo sapiens)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Sus scrofa)


name: H2O + N(2)-benzoyl-D-arginine-4-nitroanilide = 4-nitroaniline + H(+) + N(2)-benzoyl-D-arginine


name: STAT4 binds p-Y-IL23R in IL23:IL23 receptor (Bos taurus)


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Mus musculus)


name: PMM1,2 isomerise Man6P to Man1P (Bos taurus)


name: D-glucose + D-glucose 6-phosphate => 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O


name: Dissociation of insulin from insulin receptor (Homo sapiens)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADH = all-trans-lycopaoctaene + 2 diphosphate + NAD(+)


name: (11R)-dihydroartemisinic aldehyde + H2O + NAD(+) <=> (11R)-dihydroartemisinate + 2 H(+) + NADH


name: Phosphorylation of ROBO1 by ABL kinase (Drosophila melanogaster)


name: cyclic pyranopterin phosphate + diphosphate => (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate


name: ABCB1 transports PREDN,PREDL out of hepatic cells (Schizosaccharomyces pombe)


name: 2 (2E,6E)-farnesyl diphosphate + H(+) + NADH = 2 diphosphate + NAD(+) + squalene


name: Vamp2 associated secretory vesicle to plasma membrane transport (Mus musculus)


name: alpha-carotene + O2 + reduced [NADPH--hemoprotein reductase] = alpha-cryptoxanthin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GluN1:GluN2B (GRIN1:GRIN2B) di-heterotetramers bind LIN7:CASK:APBA1, DLG1 and KIF17 (Homo sapiens)


name: 2-oxobutanoate + L-glutamine = (2S)-2-aminobutanoate + 2-oxoglutaramate


name: Recruitment of CDK11p58 to the centrosomes (Sus scrofa)


name: HDAC8 deacetylates histones (Mus musculus)


name: beta-lactose + H2O => beta-D-galactose + beta-D-glucose


name: 3-methyl fatty acid + ATP + CoA => a 3-methyl fatty acyl-CoA + AMP + diphosphate


name: (2E,6E)-farnesyl diphosphate <=> beta-sesquiphellandrene + diphosphate


name: Autocatalytic activation of proMMP2 (Danio rerio)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Rattus norvegicus)


name: PKC-delta translocates to plasma membrane (Mus musculus)


name: (9Z,12Z)-octadecadienoyl-CoA + cholesterol => cholesteryl (9Z,12Z)-octadecadienoate + CoA


name: Lsm1-7 Complex binds deadenylated mRNA (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate + H2O => (-)-delta-cadinol + diphosphate


name: (S)-cis-N-methylcanadine + O2 + reduced [NADPH--hemoprotein reductase] = allocryptopine + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: NADP(+) + taurochenodeoxycholate <=> 7-oxotaurolithocholate + H(+) + NADPH


name: 3-hydroxytetradecanoate + ATP + CoA <=> 3-hydroxytetradecanoyl-CoA + AMP + diphosphate


name: anthranilate 3-monooxygenase (deaminating) activity


name: Calcium Influx through Voltage-gated Calcium Channels (Rattus norvegicus)


name: HGD dioxygenates homogentisate (Drosophila melanogaster)


name: ATP + H2O + L-glutamine(out) = ADP + H(+) + L-glutamine(in) + phosphate


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Homo sapiens)


name: ARL2:GTP binds ARL2BP (Rattus norvegicus)


name: ADP(in) + dATP(out) <=> ADP(out) + dATP(in)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol => 1-(9Z,12Z,15Z-octadecatrienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: JLP interacts with CDO complex (Homo sapiens)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Sus scrofa)


name: GRKs bind ADRB2:Catecholamine (Homo sapiens)


name: Active calmodulin binds CAMK2 (Canis familiaris)