name: Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Mus musculus)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Saccharomyces cerevisiae)


name: TLR9 processing at neutral pH (Bos taurus)


name: Mevalonate-5-phosphate is further phosphorylated (Sus scrofa)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Gallus gallus)


name: Cis-Heterodimerization of nephrin and KIRREL (Caenorhabditis elegans)


name: 3,5,7,9,11-pentaoxododecanoyl-[ACP] = 6,8-dihydroxy-3-(2-oxopropyl)-isocoumarin + H2O + holo-[ACP]


name: acetyl-CoA + tetradecanedioyl-CoA => 3-oxohexadecanedioyl-CoA + CoA


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 11-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (R)-lipoate + L-lysyl-[lipoyl-carrier protein] => H2O + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + NADH => (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+)


name: 2-oxoglutarate + 3-hydroxy-L-kynurenine => 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-glutamate


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Drosophila melanogaster)


name: TNF-mediated dimerization of procaspase-8 (Rattus norvegicus)


name: lathosterol + NAD(+) => 5alpha-cholest-7-en-3-one + H(+) + NADH


name: ORC5 binds ORC2:ORC3 (Dictyostelium discoideum)


name: IL22:IL22RA1:JAK1 binds IL10RB:TYK2 (Rattus norvegicus)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Gallus gallus)


name: Opsins act as GEFs for G alpha-t (Gallus gallus)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Homo sapiens)


name: platelet activating factor receptor activity


name: PKM dephosphorylates PEP to PYR (Canis familiaris)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O <=> (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Caenorhabditis elegans)


name: ATP(in) + CoA(in) + H(+)(out) + tetradecanoate(out) = AMP(in) + diphosphate(in) + H(+)(in) + tetradecanoyl-CoA(in)


name: Translocation of ERBB4s80 to the nucleus (Gallus gallus)


name: HLCS biotinylates ACACA:Mn2+ (Plasmodium falciparum)


name: (E)-feruloyl-AMP + CoA = (E)-feruloyl-CoA + AMP + H(+)


name: dAMP(in) + phosphate(out) => dAMP(out) + phosphate(in)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + ADP + H(+)


name: 6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone + S-adenosyl-L-methionine <=> 3-methyl-6-methoxy-2-all-trans-octaprenyl-1,4-benzoquinone + H(+) + S-adenosyl-L-homocysteine


name: PRMT1 arginine-methylates RUNX1 (Homo sapiens)


name: ANOs transport cytosolic Cl- to extracellular region (Rattus norvegicus)


name: Cipro:ALB dissociates (Canis familiaris)


name: D-galactosamine 6-phosphate = alpha-D-galactosamine 1-phosphate


name: Activated FGFR3:p-FRS bind to PPTN11 (Canis familiaris)


name: ADP-L-glycero-beta-D-manno-heptose + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + H(+)


name: SUMOylation of RAD52 with SUMO1 (Dictyostelium discoideum)


name: ALD3A1 oxidises 4HPCP to CXPA (Rattus norvegicus)


name: chromopyrrolate + H(+) + 2 H2O + NH4(+) => 2 2-iminio-3-(indol-3-yl)propanoate + H2O2


name: histone H4K12 acetyltransferase activity


name: glycine(in) + Na(+)(in) => glycine(out) + Na(+)(out)


name: Unknown deacetylase deacetylates 7K-BACE1(46-501) (Homo sapiens)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Schizosaccharomyces pombe)


name: a 5,6-dihydrouridine in mRNA + NAD(+) => a uridine in mRNA + H(+) + NADH


name: Exocytosis of platelet dense granule content (Dictyostelium discoideum)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA => a 2-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA


name: guanosine + NAD(+) => H(+) + N(2)-(ADP-D-ribosyl)-guanosine + nicotinamide


name: Phosphorylation of SHC1 by ERBB4 homodimers (Xenopus tropicalis)


name: IDUA hydrolyses Heparan sulfate chain(1) (Canis familiaris)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Caenorhabditis elegans)


name: a 2-acyl-4,6,6-triprenylphloroglucinol + diphosphate => a 2-acyl-4,6-diprenylphloroglucinol + dimethylallyl diphosphate


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) => [thioredoxin]-dithiol + glycine + H(+) + phosphate


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Xenopus tropicalis)


name: 3-sulfanylpentan-1-ol-L-cysteine + H2O = 3-sulfanyl-1-pentanol + NH4(+) + pyruvate


name: chenodeoxycholate + CoA + H(+) => chenodeoxycholoyl-CoA + H2O


name: (9Z)-octadecenoyl-CoA + (R)-carnitine => CoA + O-(9Z)-octadecenoyl-(R)-carnitine


name: N-octanoyl-(2S)-hydroxyglycine => glyoxylate + octanamide


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Schizosaccharomyces pombe)


name: atROL binds RBP1 (parenchymal cell) (Bos taurus)


name: 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and  hydrogen bromide (Dictyostelium discoideum)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Rattus norvegicus)


name: LGI1 binds ADAM22 and ADAM23 (Sus scrofa)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Bos taurus)


name: 5-dehydro-D-gluconate + H(+) + NADH => D-gluconate + NAD(+)


name: glutathione disulfide + H(+) + hydrogen sulfide => glutathione + S-sulfanylglutathione


name: 2-oxoglutarate + neamine => 6'-oxoparomamine + L-glutamate


name: Gbeta:gamma activation of PLC beta (Bos taurus)


name: 11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Bos taurus)


name: L-arginyl-L-alpha-amino acid(out) => L-arginyl-L-alpha-amino acid(in)


name: aliphatic desulfoglucosinolate sulfotransferase activity


name: Vamp8 associated secretory vesicle to plasma membrane transport (Xenopus tropicalis)


name: B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Xenopus tropicalis)


name: 3-amino-4-hydroxybenzoate + ATP + H(+) + nitrite = 3-diazo-4-hydroxybenzoate + AMP + diphosphate + H2O


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoglycerol + H2O => (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphoglycerol + H(+)


name: PVR:PVRL3 trans heterodimer interaction (Drosophila melanogaster)


name: Recruitment of PAR-3:PAR-6:aPKC complex to tight junctions (Sus scrofa)


name: TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus (Homo sapiens)


name: EGR2 and SOX10 bind the MBP gene (Homo sapiens)


name: S1P hydrolyzes SREBP1A,1C,2 (Xenopus tropicalis)


name: GATA4 and LEF1:CTNNB1 bind the ISL1 gene (Homo sapiens)


name: ALDH3A2-2 oxidizes pristanal to pristanate (Caenorhabditis elegans)


name: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO2


name: a ganglioside GT1balpha + CMP-N-acetyl-beta-neuraminate <=> CMP + ganglioside GQ1b alpha + H(+)


name: leukotriene C4(out) => leukotriene C4(in)


name: Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:TIRAP:p-IRAK4 complex (Homo sapiens)


name: mycophenolyl-CoA + propanoyl-CoA <=> (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + CoA


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H(+) + hexadecanoate


name: AMP + carcinine + diphosphate + H(+) => ATP + beta-alanine + histamine


name: 5 H(+)(in) + NADH + ubiquinone-8 => 4 H(+)(out) + NAD(+) + ubiquinol-8


name: (+)-artemisinic aldehyde + H2O + NADP(+) => (+)-artemisinate + 2 H(+) + NADPH


name: (S)-4-hydroxymandelate + H(+) + O2 => 4-hydroxybenzaldehyde + CO2 + H2O2


name: acetyl-CoA + L-methionine sulfoximine => CoA + H(+) + N-acetyl-L-methionine sulfoximine


name: Caspase-mediated cleavage of MASK (Rattus norvegicus)


name: 26S proteasome degrades Ub-NFE2L2 (Drosophila melanogaster)


name: sitosterol + UDP-alpha-D-glucose => H(+) + sitosteryl 3-beta-D-glucoside + UDP


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)


name: 3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate + H(+)


name: Exogenous soluble antigen targeted to more stable early endosome (Canis familiaris)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate => calarene + diphosphate


name: H2O + methylglyoxal <=> (R)-lactate + H(+)


name: O-acetyl-L-serine + pyrazole <=> 3-(pyrazol-1-yl)-L-alanine + acetate + H(+)


name: AH2 + chermesin D + O2 <=> A + asnovolin I + H2O


name: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = 2-oxopent-4-enoate + benzoate + H(+)


name: PICALM binds R-SNAREs (Caenorhabditis elegans)


name: 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphate + NADP(+) => 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphate + H(+) + NADPH


name: Activated FGFR1 binds FRS3 (Xenopus tropicalis)


name: a 2-acylglycerol + a fatty acid + H(+) => a 1,2-diacyl-sn-glycerol + H2O


name: (2'R)-atrovenetin + S-adenosyl-L-methionine => deoxyherqueinone + H(+) + S-adenosyl-L-homocysteine


name: alpha-D-mannose 1-phosphate + N-acetyl-D-glucosamine => 4-O-beta-D-mannopyranosyl-N-acetyl-D-glucosamine + phosphate


name: baicalin + H2O <=> baicalein + D-glucuronate + H(+)


name: (S)-2-benzoylsuccinyl-CoA + H(+) + NADH => (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA + NAD(+)


name: fibrin multimer, crosslinked:tissue plasminogen activator (two-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (two-chain):plasminogen activator inhibitor 1 (Canis familiaris)


name: factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) (Rattus norvegicus)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Sus scrofa)


name: PEX19:class I PMP binds PEX3 (Xenopus tropicalis)


name: Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADPH + O2 => 3,8-divinyl protochlorophyllide a + 2 H2O + NADP(+)


name: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alpha-aminoacyl-[protein]


name: 3-phosphonopyruvate => H(+) + phosphoenolpyruvate


name: TBC1D10A binds JFC1 (Drosophila melanogaster)


name: (3R)-hydroxy-(8Z,11Z,14Z)-eicosatrienoyl-CoA = (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H2O


name: CDP-4-dehydro-6-deoxy-D-glucose + H2O => CDP-D-glucose


name: 14-3-3epsilon attentuates NADE-related apoptosis (Sus scrofa)


name: 6-isopropenyl-3-methyloxepan-2-one + H2O + NADP(+) => dihydrocarvone + H(+) + NADPH + O2


name: H2O + hexadecanoyl-CoA => adenosine 3',5'-bisphosphate + 2 H(+) + S-hexadecanoyl-4'-phosphopantetheine


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Saccharomyces cerevisiae)


name: 7-oxo-glycodeoxycholate + H(+) + NADH => glycocholate + NAD(+)


name: GUK1 phosphorylates 6TdGMP to 6TdGDP (Rattus norvegicus)


name: (2E)-geranyl diphosphate + S-adenosyl-L-methionine <=> (E)-2-methylgeranyl diphosphate + H(+) + S-adenosyl-L-homocysteine


name: PIAS2-2 SUMOylates SUZ12 with SUMO1 (Mus musculus)


name: (1S)-2-methyl-cyclohexylamine + H2O + NADP(+) <=> 2-methylcyclohexanone + H(+) + NADPH + NH4(+)


name: ATP + pyridoxine <=> ADP + H(+) + pyridoxine 5'-phosphate


name: Estrogen receptor binds IGF1R and SHC1 in response to estrogen (Drosophila melanogaster)


name: ADGRG heterodimer translocates to plasma membrane (Rattus norvegicus)


name: Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) (Sus scrofa)


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Rattus norvegicus)


name: (3R)-hydroxytriacontanoyl-CoA <=> (2E)-triacontenoyl-CoA + H2O


name: K+-independent Li+/Ca2+ exchanger transport (Rattus norvegicus)


name: AcCho is hydrolyzed to Cho and acetate by ACHE (Gallus gallus)


name: H2O + N(8)-acetylspermidine + O2 <=> 4-acetamidobutanal + H2O2 + propane-1,3-diamine


name: alpha-pinene oxide + H2O + NAD(+) => (1S,5S)-alpha-pinene + H(+) + NADH + O2


name: ethyl formate + H2O + N-(2-ethyl-6-methylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin] => acetochlor + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Gallus gallus)


name: glycodeoxycholate + H2O <=> deoxycholate + glycine


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+) => 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + H(+) + NADPH


name: Zinc is an agonist of GPR39 (Sus scrofa)


name: (E)-pent-3-en-2-one + H(+) + NADPH => NADP(+) + pentan-2-one


name: a cytidine in tRNA + acetyl-CoA + ATP + H2O <=> ADP + an N(4)-acetylcytidine in tRNA + CoA + H(+) + phosphate


name: IRE1 dimer autophosphorylates (Homo sapiens)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Canis familiaris)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Danio rerio)


name: SLC38A9 binds Ragulator:Rag dimers (Gallus gallus)


name: MITF-M dependent DICER1 gene expression (Homo sapiens)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Canis familiaris)


name: CTNNBIP1 binds beta-catenin (Mus musculus)


name: prostaglandin A2-S-(R)-glutathione => glutathione + prostaglandin A2


name: (4S)-limonene + O2 + reduced [NADPH--hemoprotein reductase] => (1S,6R)-isopiperitenol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 ATP + 2 H2O + hydrogenobyrinate + 2 L-glutamine => 2 ADP + 2 H(+) + hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 phosphate


name: TFAM binds to mitochondrial promoters (Caenorhabditis elegans)


name: (3R)-hydroxydecanoyl-[ACP] => (2E)-decenoyl-[ACP] + H2O


name: beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => all-trans-zeaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: methylglyoxal reductase (NADPH) activity


name: an N-(fatty acyl)-L-glutamine + H2O = a fatty acid + L-glutamine


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Plasmodium falciparum)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Dictyostelium discoideum)


name: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: Gap-filling DNA synthesis in SDSA (Homo sapiens)


name: (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O


name: ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA (Homo sapiens)


name: Ficolin-1 binds to molecular patterns on the target cell surface (Homo sapiens)


name: a 4,5-didehydrojasmonate + H(+) + NADPH => a jasmonate + NADP(+)


name: ent-kaur-16-en-19-oate + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> gibberellin A12 aldehyde + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: 1,6-dimethoxyphenazine N(5)-oxide + S-adenosyl-L-homocysteine => 1-hydroxy-6-methoxyphenazine N(10)-oxide + S-adenosyl-L-methionine


name: Receptor-mediated uptake of HA (Rattus norvegicus)


name: Dephosphorylation of p130 (RBL2) by PP2A (Caenorhabditis elegans)


name: Delta12-PGJ2 is dehydrated to 15d-PGJ2 (Homo sapiens)


name: FDPS dimer transfers IPPP to GPP (Plasmodium falciparum)


name: CoA + pyrethrin I => (1R,3R)-chrysanthemoyl-CoA + (Z,S)-pyrethrolone


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine = (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Gallus gallus)


name: USP19 deubiquitinates RNF123 (Sus scrofa)


name: 5-hydroxyxanthotoxin + S-adenosyl-L-methionine <=> isopimpinellin + S-adenosyl-L-homocysteine


name: p-6Y-VEGFR2 binds SH2D2A (Rattus norvegicus)


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Bos taurus)


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: 3,4-dihydroxybenzaldehyde + H2O + NADP(+) = 3,4-dihydroxybenzoate + 2 H(+) + NADPH


name: ANTXR1-bound pagA(197-794) forms oligomers (Homo sapiens)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Caenorhabditis elegans)


name: PKC alpha interacts with and phosphorylates KIT (Canis familiaris)


name: ATP + L-seryl-[receptor-protein] <=> ADP + H(+) + O-phospho-L-seryl-[receptor-protein]


name: ribonucleotidyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-uridine-RNA


name: CDC42 GDIs block activation of CDC42 (Drosophila melanogaster)


name: PAK1 autophosphorylates (Canis familiaris)


name: Telomere shortening during replicative exhaustion (Rattus norvegicus)


name: mannose(a1-4)glucosaminyl-acyl-PI + phosphatidylethanolamine -> (ethanolamineP) mannose(al1-4)glucosaminyl-acyl-PI + diacylglycerol (Canis familiaris)


name: CoA + H(+) + N-octadecanoyl-(4R)-hydroxysphinganine => (4R)-hydroxysphinganine + octadecanoyl-CoA


name: a ganglioside GA1 (d18:1(4E)) + GDP-beta-L-fucose => a ganglioside Fuc-GA1 (d18:1(4E)) + GDP + H(+)


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Xenopus tropicalis)


name: (S)-2,3-dihydrodipicolinate + NADP(+) = dipicolinate + H(+) + NADPH


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)


name: GBA2 hydrolyzes GlcCer (plasma membrane) (Caenorhabditis elegans)


name: A + semiviriditoxin => AH2 + methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate


name: WNT:FZD complex promotes G-protein nucleotide exchange (Gallus gallus)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Homo sapiens)


name: a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SHP2 phosphatase binds CTLA-4 (Bos taurus)


name: a fatty acid + ATP = a fatty acyl phosphate + ADP


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Mus musculus)


name: PAR-PARP1,PAR-PARP2 dissociate from FEN1 and POLB (Homo sapiens)


name: [amino-group carrier protein]-C-terminal-L-glutamate + ATP + L-glutamate = [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ADP + H(+) + phosphate


name: "glutamate--[amino group carrier protein] ligase"


name: p-S92,203-BRF1 binds 14-3-3 (Caenorhabditis elegans)


name: NAD(+) + UDP-alpha-D-glucose = H(+) + NADH + UDP-3-oxo-alpha-D-glucose


name: 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Mus musculus)


name: ATP + N(4)-acetylcytidine <=> ADP + H(+) + N(4)-acetylcytidine 5'-phosphate


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Bos taurus)


name: mTORC1 binds RHEB:GTP (Schizosaccharomyces pombe)


name: (6E)-8-hydroxygeraniol + NADP(+) => (6E)-8-hydroxygeranial + H(+) + NADPH


name: Activation of EPACs by cAMP (Caenorhabditis elegans)


name: SHP2 interacts with p-KIT (Xenopus tropicalis)


name: VMAT1/2 can mediate the transport of biogenic amines (Xenopus tropicalis)


name: Uncleaved Pink1 accumulates in damaged mitochondria (Danio rerio)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-eicosanoyl-sn-glycero-3-phosphocholine <=> 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: CaMKII binds activated NMDA receptor (Homo sapiens)


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Xenopus tropicalis)


name: Hydrolysis of internal thioester in C4b (Rattus norvegicus)


name: JAK2 Phosphorylates IRS in Response to Leptin (Homo sapiens)


name: S100A8:S100A9 binds TLR4:LY96 (Canis familiaris)


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Sus scrofa)


name: H2O + orobanchol = 5-hydroxy-3-methylfuran-2(5H)-one + orobanchol ABC-rings


name: [amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ADP + H(+) + phosphate => [amino-group carrier protein]-C-terminal-L-glutamate + ATP + L-2-aminoadipate


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: ALOX12:Fe2+ oxidises DPAn-6 to 14(S)-HDPAn-6 (Homo sapiens)


name: 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Bos taurus)


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)


name: PI3K synthesizes PIP3 downstream of ALK (Sus scrofa)


name: TRIM27 polyubiquitinates PTEN (Bos taurus)


name: Tyrosinase oxidises tyrosine to dopaquinone (Sus scrofa)


name: all-trans-violaxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => all-trans-antheraxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: RAB33B:GTP binds RIC1:RGP1 (Danio rerio)


name: LIPT2 transfers octanoyl group to GCSH (Mus musculus)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Sus scrofa)


name: a 1-acyl-sn-glycero-3-phosphate + dodecanoyl-CoA = a 1-acyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Xenopus tropicalis)


name: O2 + progesterone + reduced [NADPH--hemoprotein reductase] = 21-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glutamate uptake by astrocytes (Rattus norvegicus)


name: Phosphorylation and activation of CHEK2 by ATM (Bos taurus)


name: SCF:FBXL7 binds AURKA (Canis familiaris)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 <=> N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-taurine


name: Antizyme OAZ binds to Ornithine decarboxylase (Mus musculus)


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Sus scrofa)


name: (3E)-2-oxohex-3-enedioate + H(+) <=> 2-oxopent-4-enoate + CO2


name: (19E)-geissoschizine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + rhazimal


name: CK2:FACT phosphorylates TP53 (Rattus norvegicus)


name: ATP + L-aspartyl-tRNA(Asn) => 4-phosphooxy-L-aspartyl-tRNA(Asn) + ADP + H(+)


name: 2-(1-hydroxyethyl)thiamine diphosphate + 2-oxobutanoate = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + thiamine diphosphate


name: SUMOylation of NR1H4 with SUMO1 (Gallus gallus)


name: ALDHs oxidise atRAL to atRA (Danio rerio)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Homo sapiens)


name: Dimerization of p-S446-IRF5 (Sus scrofa)


name: a uridine in rRNA => a pseudouridine in rRNA


name: 3-oxoisoapionate 4-phosphate + H(+) => CO2 + L-erythrulose 1-phosphate


name: Activated FGFR1 mutants and fusions phosphorylate PLCG1 (Homo sapiens)


name: ALDHs oxidise atRAL to atRA (Rattus norvegicus)


name: PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Drosophila melanogaster)


name: L-alanyl-D-glutamate + meso-2,6-diaminoheptanedioate => H2O + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate


name: SALM2 associate with AMPA and NMDA receptors (Danio rerio)


name: Fusion of COPII vesicle with Golgi complex (Danio rerio)


name: H2O + melibiose <=> D-galactose + D-glucose


name: glutarate(in) + kynurenate(out) = glutarate(out) + kynurenate(in)


name: PTGS1,2 dimers bind PTGS Inhibitors (Sus scrofa)


name: 3-aminohexane + H2O + NADP(+) = H(+) + hexan-3-one + NADPH + NH4(+)


name: ATP + beta-nicotinamide D-riboside <=> ADP + beta-nicotinamide D-ribonucleotide + H(+)


name: SEMA3E binds to PLXND1 (Rattus norvegicus)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Danio rerio)


name: E2F6:TFDP1:EPC1 binds the PRC2 complex (Rattus norvegicus)


name: 6-methoxymellein + H(+) + S-adenosyl-L-homocysteine => 6-hydroxymellein + S-adenosyl-L-methionine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA


name: chorismate + NH4(+) = (2S)-2-amino-4-deoxychorismate + H2O


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Canis familiaris)


name: CHDH oxidises Cho to BETALD (Dictyostelium discoideum)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Dictyostelium discoideum)


name: Collagen type XIX degradation (Sus scrofa)


name: Rheb in the MTORC1 complex hydrolyses GTP (Xenopus tropicalis)


name: 2-deoxy-D-ribose + ATP <=> 2-deoxy-D-ribose 5-phosphate + ADP + H(+)


name: CCR4-NOT complex deadenylates mRNA (Homo sapiens)


name: MITF-M dimer binds SIRT1 promoter (Homo sapiens)


name: K63polyUb-RIPK1 is deubiquitinated (Sus scrofa)


name: OLR1 binds to oxidized LDL (Rattus norvegicus)


name: PTK6 phosphorylates STAT3 (Rattus norvegicus)


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Caenorhabditis elegans)


name: Inactivation of Rho-GTP by p190RhoGAP (Homo sapiens)


name: PGA2 is dehydrated to 15d-PGA2 (Homo sapiens)


name: XPO1 (CRM1) binds to BACH1:Hemes (Bos taurus)


name: ACLY tetramer binds ETC-1002-CoA (Sus scrofa)


name: FUT2 transfers Fuc to LeA to form LeB (Xenopus tropicalis)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GM4 (d18:1(4E)) + CMP + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-L-serine = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: dihydroxyacetone phosphate => D-glyceraldehyde 3-phosphate


name: CSF3 dimer:CSFR binds CSFR (Canis familiaris)


name: a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+) => a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O


name: Binding of the MCC complex to the APC/C complex (Sus scrofa)


name: glycine + H(+) + hexadecanoyl-CoA = 1-deoxymethyl-3-dehydrosphinganine + CO2 + CoA


name: Transhomodimerization of Nectin-like (Necl) proteins (Mus musculus)


name: Activated FGFR4 binds SHC1 (Canis familiaris)


name: a di-trans,poly-cis-dolichyl diphosphate + H(+) + N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginy-[protein] => a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein]


name: SUMOylation of DDX5 with SUMO1 (Sus scrofa)


name: H2O2 + IC-asc-DeltaC7-CoA => IC-asc-C7-CoA + O2


name: 6-amino-2-oxohexanoate + H2O2 + NH4(+) => D-lysine + H2O + O2


name: ABP1 binds SHANK proteins (Canis familiaris)


name: Homodimerization of ERBB4 (Rattus norvegicus)


name: Activated FGFR4 phosphorylates FRS3 (Xenopus tropicalis)


name: 2-oxoglutarate + L-histidyl-[ankyrin-repeat domain protein] + O2 <=> (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: (2R,3S)-3-methylmalate + NAD(+) = 2-oxobutanoate + CO2 + NADH


name: a 1,2-diacyl-sn-glycerol + phosphate => a 1,2-diacyl-sn-glycero-3-phosphate + H2O


name: ADP + Fe(III)-petrobactin(in) + H(+) + phosphate => ATP + Fe(III)-petrobactin(out) + H2O


name: 5-hydroxymethylfurfural + O2 => 2,5-diformylfuran + H2O2


name: CaMKK autophosphorylates in the nucleus (Bos taurus)


name: Autocatalytic activation of proMMP13 (Homo sapiens)


name: Bitter compound binds bitter taste receptor (TAS2R) (Homo sapiens)


name: 2-methoxyestrone + H(+) + S-adenosyl-L-homocysteine => 2-hydroxyestrone + S-adenosyl-L-methionine


name: 5,6,7,8-tetrahydropteridine + NAD(+) = 6,7-dihydropteridine + H(+) + NADH


name: ERKs are inactivated by protein phosphatase 2A (Caenorhabditis elegans)


name: (13E)-labda-7,13-dien-15-yl diphosphate => geranylgeranyl diphosphate


name: (2E,15Z)-tetracosadienoyl-CoA + H(+) + NADPH = (15Z)-tetracosenoyl-CoA + NADP(+)


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z-octadecadienoyl)-glycerol = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA (Canis familiaris)


name: 12-(phosphooxy)octadecanoate + H2O => 12-hydroxyoctadecanoate + phosphate


name: JET binds cytosolic TIM, facilitating its ubiquitination (Drosophila melanogaster)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Canis familiaris)


name: NPAS4 binds ARNTL (BMAL1) (Rattus norvegicus)


name: DVL2 binds phosphorylated WWTR1 (TAZ) (Mus musculus)


name: Binding of PI3K to complex of GRB2:GAB1 and ligand-responsive p-6Y-EGFR mutants (Homo sapiens)


name: NT5C3B hydrolyses 7MGP to 7MG (Homo sapiens)


name: Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)


name: Cho transports from the extracellular space to the cytosol (Mus musculus)


name: ADP + Ca(2+)(out) + H(+) + phosphate => ATP + Ca(2+)(in) + H2O


name: p-S256-Aquaporin-2 passively transports water into cell (Xenopus tropicalis)


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Gallus gallus)


name: IL17RA:IL17RE binds IL17C dimer (Homo sapiens)


name: B4GALT7 transfers Gal group to xylosyl-unit of the tetrasaccharide linker (Bos taurus)


name: albendazole + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + hydroxyalbendazole + oxidized [NADPH--hemoprotein reductase]


name: 4-methylsulfanyl-2-oxobutanoate + L-alanine => D-methionine + pyruvate


name: dimethylallyl diphosphate + 5 isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + 5 diphosphate


name: "hexaprenyl diphosphate synthase (prenyl-diphosphate specific)"


name: 4-O-{[(2R)-2-alpha-D-glucosyl-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n H(+) + n UDP => 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP-alpha-D-glucose


name: RAS proteins are depalmitoylated (Caenorhabditis elegans)


name: Disassembly of SR-BI-bound spherical HDL (Canis familiaris)


name: Parkin transfers Ub to misfolded proteins (Mus musculus)


name: creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Xenopus tropicalis)


name: Binding of the MCC complex to the APC/C complex (Xenopus tropicalis)


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Canis familiaris)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Mus musculus)


name: DCN (decorin) degradation by MMP14 (Rattus norvegicus)


name: H2O + L-isoleucine + O2 = (S)-3-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: a nitrile + 2 H2O <=> a carboxylate + NH4(+)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: nsp12 acquires Fe-S cluster cofactors (Homo sapiens)


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Sus scrofa)


name: H(+) + NADH + O2 + propane = H2O + NAD(+) + propan-2-ol


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Gallus gallus)


name: 2-demethylmenaquinol-8 + dimethyl sulfoxide => 2-demethylmenaquinone-8 + dimethyl sulfide + H2O


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine


name: SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH (Xenopus tropicalis)


name: H(+) + o-quinone methide + penilactone D => penilactone B


name: A + H2O + quinolin-6-ol <=> 6-hydroxyquinolin-2(1H)-one + AH2


name: D-glutamate + pyridoxal 5'-phosphate => 2-oxoglutarate + pyridoxamine 5'-phosphate


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Sus scrofa)


name: N-(4-oxobutylpyrrolinium) ion <=> 1-formylpyrrolizidine


name: H(+)(out) + L-arabinose(out) => H(+)(in) + L-arabinose(in)


name: NADPH + nitroglycerin <=> 1,3-dinitroglycerol + NADP(+) + nitrite


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Bos taurus)


name: dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine (Drosophila melanogaster)


name: hexadecanoyl-AMP + holo-[ACP] = AMP + H(+) + hexadecanoyl-[ACP]


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: CBL ubiquitinates FRS2 and FGFR1 (Canis familiaris)


name: CoA + octyl hexadecanoyl => hexadecanoyl-CoA + octan-1-ol


name: 22-hydroxydocosanoate + O2 + reduced [NADPH--hemoprotein reductase] => 22-oxodocosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: UROD decarboxylates URO1 to COPRO1 (Bos taurus)


name: PDE4A,C,D hydrolyse cAMP (Canis familiaris)


name: 3-hydroxyoctadecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 3,18-dihydroxyoctadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: IL33:IL1RL1 binds IL1RAP-1 (Rattus norvegicus)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Gallus gallus)


name: (3S)-3-hydroxybutanoyl-CoA = (2E)-butenoyl-CoA + H2O


name: A + H2O + quinoline => AH2 + quinolin-2(1H)-one


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Mus musculus)


name: steviol + UDP-alpha-D-glucose <=> H(+) + steviolmonoside + UDP


name: OPLAH hydrolyses OPRO to L-Glu (Dictyostelium discoideum)


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Xenopus tropicalis)


name: Elastin degradation by elastin-degrading extracellular proteinases (Sus scrofa)


name: ME2 tetramer decarboxylates MAL to PYR (Mus musculus)


name: ATP + glutathione(out) + H2O => ADP + glutathione(in) + H(+) + phosphate


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Homo sapiens)


name: H2O + plasmodiophorol A <=> plasmodiophorol C


name: LHPP:Mg2+ dimer hydrolyses PPi (Caenorhabditis elegans)


name: 1-deoxy-D-xylulose 5-phosphate + A + H2O => AH2 + D-ribulose 5-phosphate


name: PGC2 is isomerised to PGB2 (Homo sapiens)


name: An atROL isomerase isomerises atROL to 11cROL (Homo sapiens)


name: G-protein subunits dissociate from WNT:FZD complex (Homo sapiens)


name: Activated PTK6 binds CDKN1B (Xenopus tropicalis)


name: RHOG binds effectors at the plasma membrane (Xenopus tropicalis)


name: guanosine 2'-phosphate + H(+) => 2',3'-cyclophospho-GMP + H2O


name: RHOT2 hydrolyzes GTP (Drosophila melanogaster)


name: HP1 alpha binds Histone H3K9(me)3 (Dictyostelium discoideum)


name: OAT1-3 transport organic anions with antiport of dicarboxylic acids (Danio rerio)


name: 2-phenylacetaldehyde + H(+) + NADPH => 2-phenylethanol + NADP(+)


name: AH2 + ATP + 2 Co(II)-[trimethylamine-specific corrinoid protein] + H2O <=> A + ADP + 2 Co(I)-[trimethylamine-specific corrinoid protein] + 3 H(+) + phosphate


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Caenorhabditis elegans)


name: MRN complex bound to DNA ends recruits ATM (Canis familiaris)


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: a plastoquinol + 2 H(+)(in) + 2 oxidized [plastocyanin] => a plastoquinone + 4 H(+)(out) + 2 reduced [plastocyanin]


name: (5R)-5-hydroxy-L-lysyl-[collagen] + hypobromite + L-methionyl-[collagen] = [collagen]-(5R)-5-hydroxy-L-lysyl-N-S-L-methionyl-[collagen] + bromide + H(+) + H2O


name: Activated FGFR2 phosphorylates PPTN11 (Canis familiaris)


name: low-affinity nitrate transmembrane transporter activity


name: p62 links damaged mitochondria to LC3 (Homo sapiens)


name: Estrogen receptor binds IGF1R and SHC1 in response to estrogen (Sus scrofa)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Mus musculus)


name: p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Xenopus tropicalis)


name: 2 cob(II)alamin + NADH => 2 cob(I)alamin + H(+) + NAD(+)


name: SETD8 monomethylates histone H4 (Homo sapiens)


name: Docking and transport of the RNP:Karyopherin complex through the nuclear pore (Homo sapiens)


name: CO2 + 2 H2O + NAD(+) + proviolacein => 2 H(+) + NADH + 2 O2 + protodeoxyviolaceinate


name: NEIL3 cleaves 5-guanidinohydantoin (Gallus gallus)


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Canis familiaris)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Caenorhabditis elegans)


name: (R)-carnitine + an acyl-CoA = CoA + O-acyl-(R)-carnitine


name: NADPH + O2 + putrescine => H2O + N-hydroxyputrescine + NADP(+)


name: Acidification of Tf:TfR1 containing endosome (Sus scrofa)


name: p-Y705-STAT3, p-Y641-STAT6 dimerise (Xenopus tropicalis)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Saccharomyces cerevisiae)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Rattus norvegicus)


name: butanoyl-CoA + hexan-1-ol <=> CoA + hexyl butanoate


name: (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein] => dodecanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 4 H(+) + 3 L-methionine => H2O + Mg-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine


name: Collagen type I degradation by MMP15 (Caenorhabditis elegans)


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Homo sapiens)


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Homo sapiens)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH => 7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+)


name: Activated integrin alphaIIb beta3 binds SHC1 (Gallus gallus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)


name: aldosterone + 2 H2O + 2 oxidized [adrenodoxin] => 18-hydroxycorticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: 26S proteosome degrades ODC holoenzyme complex (Danio rerio)


name: Myt-1 mediated phosphorylation of Cyclin A:Cdc2 (Homo sapiens)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Mus musculus)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Sus scrofa)


name: Caspase-mediated cleavage of Desmoglein 2 (Caenorhabditis elegans)


name: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+)


name: 4 ATP = cyclic tetraadenylate + 4 diphosphate


name: (3R)-3-hydroxydecanoyl-CoA => (2E)-decenoyl-CoA + H2O


name: PDCL promotes G-protein beta 5 folding (Sus scrofa)


name: CBL ubiquitinates FRS2 and FGFR4 (Rattus norvegicus)


name: 2,6-dihydroxypyridine + 4-(methylamino)butanoate + H(+) => 2,6-dihydroxypseudooxynicotine + H2O


name: glycerol + H(+) + tetradecanoate => 1-tetradecanoyl-sn-glycerol + H2O


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Sus scrofa)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Bos taurus)


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Bos taurus)


name: The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Xenopus tropicalis)


name: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-apiose = 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone + H(+) + UDP


name: a fatty acyl-CoA + sphing-4-enine <=> an N-acylsphing-4-enine + CoA + H(+)


name: (E)-hept-2-enoate + 2 H(+) + NADPH => (E)-hept-2-enal + H2O + NADP(+)


name: Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Canis familiaris)


name: H2O + N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein] <=> 3-deoxyglucosone + L-lysyl-[protein] + phosphate


name: H(+) + NADPH + uracil => 5,6-dihydrouracil + NADP(+)


name: GDP-alpha-D-rhamnose + NADP(+) => GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Canis familiaris)


name: L1 interaction with Integrins (Caenorhabditis elegans)


name: NOTCH3 coactivator complex binds HEYL gene promoter (Homo sapiens)


name: (2S)-2-hydroxy-2-(thiophen-3-yl)acetonitrile => 3-formylthiophene + hydrogen cyanide


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Homo sapiens)


name: MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Gallus gallus)


name: adenosine 3',5'-bisphosphate + H(+) + O-sulfo-L-tyrosine-[protein] => 3'-phosphoadenylyl sulfate + L-tyrosyl-[protein]


name: IMPAD1 hydrolyses PAP to AMP (Bos taurus)


name: Inactivation of Cyclin E:Cdk2 complexes by p27/p21 (Xenopus tropicalis)


name: DAG stimulates protein kinase C-delta (Xenopus tropicalis)


name: carbendazim + H2O = 2-aminobenzimidazole + CO2 + methanol


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Homo sapiens)


name: 1-octadecanoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O => 1-octadecanoyl-sn-glycero-3-phosphoserine + 9,10-epoxyoctadecanoate + H(+)


name: 4-(hydroxyamino)quinoline N-oxide + H2O + 2 NADP(+) => 4-nitroquinoline N-oxide + 2 H(+) + 2 NADPH


name: Phosphorylation of the Emi1 DSGxxS degron by Plk1 (Bos taurus)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 12-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3,5-dihydroxyanisole + S-adenosyl-L-methionine <=> 3,5-dimethoxyphenol + H(+) + S-adenosyl-L-homocysteine


name: ALDH3A2-1 oxidises HD2NAL to PALM (Canis familiaris)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Canis familiaris)


name: Formation of the RBBP5:ASH2L heterodimer (Caenorhabditis elegans)


name: 9beta-pimara-7,15-diene-3beta-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 9beta-pimara-7,15-diene + O2 + reduced [NADPH--hemoprotein reductase]


name: (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose => (20S)-ginsenoside Rg3 + H(+) + UDP


name: RHAG transports CO2 from extracellular region to cytosol (Sus scrofa)


name: [sulfur carrier]-SH + AH2 + N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine = 2-sulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + H(+) + L-methionine


name: H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline <=> 5a,11a-dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] <=> H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate


name: beta-alanine + CO2 => H(+) + L-aspartate


name: ACY3:Zn2+ dimer hydrolyses mercapturic acids (Homo sapiens)


name: LIG1 binds APEX1 and PCNA at SSB (Sus scrofa)


name: ADP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + L-glutamate + phosphate => ATP + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + H2O + L-glutamine


name: RHOB binds effectors at the plasma membrane (Saccharomyces cerevisiae)


name: 4-methylcatechol + CO2 + NADH => (1R,6S)-1,6-dihydroxy-4-methylcyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: H(+) + NADPH + O2 + pentachlorophenol => 2,3,5,6-tetrachloro-1,4-benzoquinone + chloride + H2O + NADP(+)


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA = an acyl-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + holo-[ACP]


name: HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38 (Homo sapiens)


name: sn-glycerol 3-phosphate + ubiquinone-8 => dihydroxyacetone phosphate + ubiquinol-8


name: 2-oxoglutarate + fumigatonoid C + O2 = CO2 + H2O + novofumigatonin + succinate


name: tiglyl-CoA + H2O <=> alpha-methyl-beta-hydroxybutyryl-CoA (Homo sapiens)


name: Fall Back to Closed Pre-initiation Complex (Xenopus tropicalis)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Xenopus tropicalis)


name: griseophenone B + H(+) + O2 + reduced [NADPH--hemoprotein reductase] = desmethyl-dehydrogriseofulvin + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: D-threo-isocitrate + NAD(+) => 2-oxoglutarate + CO2 + NADH


name: dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O => dTDP-4-dehydro-6-deoxy-alpha-D-glucose


name: protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Mus musculus)


name: 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase activity


name: p-S256-Aquaporin-2 passively transports water into cell (Rattus norvegicus)


name: CDK4 inhibitors bind CDK4 (Schizosaccharomyces pombe)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + H2O


name: D-glucose + NAD(+) => D-glucono-1,5-lactone + H(+) + NADH


name: N,N-dihydroxy-L-aspartate = (2S)-2-nitrosobutanedioate + H2O


name: guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Mus musculus)


name: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 (Danio rerio)


name: Interleukin-1 family precursors are cleaved by caspase-1 (Bos taurus)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Gallus gallus)


name: HMOX1 dimer, HMOX2 cleave heme (Sus scrofa)


name: RLBP1 binds atROL to form RLBP1:atROL (Gallus gallus)


name: NRF1:PPARGC1B binds the ALAS1 promoter (Homo sapiens)


name: C3G stimulates nucleotide exchange on Rap1 (Homo sapiens)


name: WIP binds WASP,N-WASP, activating them (Canis familiaris)


name: dihydroxyacetone phosphate + H2O <=> dihydroxyacetone + phosphate


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Bos taurus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> a 1-acyl-2-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + sn-glycerol 3-phosphocholine


name: Ral-GDS binds to Ras-GTP (Drosophila melanogaster)


name: ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4 (Canis familiaris)


name: Carbonic anhydrase hydrates carbon dioxide (cytosol) (Bos taurus)


name: Deacetylation of cleaved cohesin (Mus musculus)


name: PIP3 recruits AKT to the membrane (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + germacrene A


name: L-methionine(in) + L-phenylalanine(out) = L-methionine(out) + L-phenylalanine(in)


name: TEADs:YAP1 binds CTGF gene (Homo sapiens)


name: ATP + H2O + L-alanyl-L-glutamate(out) <=> ADP + H(+) + L-alanyl-L-glutamate(in) + phosphate


name: HERC2 and PIAS4 are recruited to DNA DSBs (Homo sapiens)


name: Keratin filaments bind cell-cell adhesion complexes (Bos taurus)


name: 4-phenylbutan-2-amine + H2O + NAD(+) => 4-phenylbutan-2-one + H(+) + NADH + NH4(+)


name: RHOC activates endoplasmic reticulum effectors (Saccharomyces cerevisiae)


name: PLG(20-810) binds aprotinin (Rattus norvegicus)


name: beta-D-gentiobiosyl beta-D-glucosyl crocetin + H(+) + UDP => bis(beta-D-glucosyl) crocetin + UDP-alpha-D-glucose


name: alpha-D-ribose 1-phosphate + cytosine => cytidine + phosphate


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Sus scrofa)


name: 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde => 7,8-dihydroneopterin


name: (2E)-octenoate + 2 H(+) + NADPH => (2E)-octenal + H2O + NADP(+)


name: (9Z)-octadecenoyl-CoA + 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate = 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Rattus norvegicus)


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Canis familiaris)


name: PVR:PVRL3 trans heterodimer interaction (Canis familiaris)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Schizosaccharomyces pombe)


name: PI3K synthesizes PIP3 downstream of ALK (Bos taurus)


name: D-galactose 6-phosphate + NAD(+) = 6-phospho-D-galactono-1,5-lactone + H(+) + NADH


name: 3-dehydro-4-O-phospho-D-erythronate + H(+) = CO2 + dihydroxyacetone phosphate


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Xenopus tropicalis)


name: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal


name: nigerose + phosphate <=> beta-D-glucose 1-phosphate + D-glucose


name: EFNBs bind SFKs (Caenorhabditis elegans)


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Homo sapiens)


name: Mitochondrial FPGS-1 transforms THF to THFPG (Xenopus tropicalis)


name: caldopentamine + 2 H(+) + S-methyl-5'-thioadenosine => norspermine + S-adenosyl 3-(methylsulfanyl)propylamine


name: PRDX5 reduces peroxynitrite to nitrite using TXN2 (Mus musculus)


name: 2-oxoglutarate + O2 + octadecanoyl-CoA <=> 2-hydroxyoctadecanoyl-CoA + CO2 + succinate


name: Crk binding to p130cas (Rattus norvegicus)


name: Exocytosis of azurophil granule membrane proteins (Danio rerio)


name: octacosanoyl-CoA + sphinganine <=> CoA + H(+) + N-(octacosanoyl)-sphinganine


name: a ganglioside GD3 + acetyl-CoA => a ganglioside Ac-O-7-GD3 + CoA


name: LDH tetramer reduces PYR to LACT (Sus scrofa)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Canis familiaris)


name: Activation of Potassium transport channels (Bos taurus)


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Homo sapiens)


name: TCF/LEF:CTNNB1 bind canonical WNT target promoters (Homo sapiens)


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Bos taurus)


name: Phosphorylation and activation of PLCG (Homo sapiens)


name: ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (Rattus norvegicus)


name: (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione => (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Xenopus tropicalis)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3B (GRIN3B) (Homo sapiens)


name: Association of HMGB1/HMGB2 with chromatin (Canis familiaris)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)


name: L-aspartate(out) + L-methionine(in) => L-aspartate(in) + L-methionine(out)


name: Dimerization of phosphorylated IRF3/IRF7 (Mus musculus)


name: ATP + D-alanine + D-serine = ADP + D-alanyl-D-serine + H(+) + phosphate


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Dictyostelium discoideum)


name: (S)-3-hydroxybutanoate(out) + H(+)(out) => (S)-3-hydroxybutanoate(in) + H(+)(in)


name: (E)-coniferaldehyde + H2O + NAD(+) <=> (E)-ferulate + 2 H(+) + NADH


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Saccharomyces cerevisiae)


name: SLC16A3,7,8 cotransport monocarboxylates, H+ from extracellular region to cytosol (Rattus norvegicus)


name: PLCG2 translocates from cytosol to plasma membrane (Bos taurus)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Danio rerio)


name: 3-hydroxypropanal + H(+) + NADH => NAD(+) + propane-1,3-diol


name: voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential


name: 1,6-dihydroxyphenazine + S-adenosyl-L-methionine = 1-hydroxy-6-methoxyphenazine + H(+) + S-adenosyl-L-homocysteine


name: CDP-ETA and DAG are converted to PE by CEPT1/EPT1 (Caenorhabditis elegans)


name: (+)-vincadifformine + O2 + reduced [NADPH--hemoprotein reductase] = (+)-minovincinine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Canis familiaris)


name: AZD1979 + H2O => AZD1979 oxetane hydrolysis product + H(+)


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Saccharomyces cerevisiae)


name: ATM phosphorylates HERC2 (Canis familiaris)


name: KIF17 enters the cilium (Canis familiaris)


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Xenopus tropicalis)


name: pyridoxine 5'-phosphate synthase activity


name: Active JNK moves to the nucleus and phosphorylates different transcription factors (Drosophila melanogaster)


name: RHOA binds effectors at the plasma membrane (Xenopus tropicalis)


name: CAK-mediated phosphorylation of Cyclin B1:Cdc2 complexes (Canis familiaris)


name: CPN, CPB2 cleave C3a, C5a (Homo sapiens)


name: 7(1)-hydroxychlorophyllide a + NADP(+) <=> chlorophyllide b + H(+) + NADPH


name: p130 (RBL2) associates with MuvB to form DREAM complex (Canis familiaris)


name: O2 + phylloquinone + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + omega-hydroxyphylloquinone + oxidized [NADPH--hemoprotein reductase]


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O <=> (6S)-5,6,7,8-tetrahydrofolate + formaldehyde


name: beta-alanyl-5'-AMP + holo-[peptidyl-carrier protein] = AMP + beta-alanyl-[peptidyl-carrier protein] + H(+)


name: H2O + P(1),P(6)-bis(5'-adenosyl) hexaphosphate <=> adenosine 5'-pentaphosphate + AMP + 2 H(+)


name: a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol


name: (6S)-5,6,7,8-tetrahydrofolate + vanillate <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 3,4-dihydroxybenzoate


name: a 2-oxocarboxylate + L-alanine => an L-alpha-amino acid + pyruvate


name: PDPK1 phosphorylates SGK1 (Canis familiaris)


name: 5-phosphooxy-L-glutamyl-tRNA(Gln) + NH4(+) <=> H(+) + L-glutaminyl-tRNA(Gln) + phosphate


name: 2xPDXK:2xZn2+ phosphorylates PXL (Plasmodium falciparum)


name: NaS2 co-transports sulphate and two sodium ions (Canis familiaris)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(in) + ATP + H2O => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate(out) + ADP + H(+) + phosphate


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 5beta-cholestane-3alpha,7alpha-diol + O2 + reduced [NADPH--hemoprotein reductase]


name: TFAP2C homodimer binds MYC and KDM5B (Rattus norvegicus)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Dictyostelium discoideum)


name: SLCO1B3 transports ALB:(GCCA, TCCA) from extracellular region to cytosol (Bos taurus)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Xenopus tropicalis)


name: H(+) + sulfate + thiosulfate => H2O + trithionate


name: (9E)-octadecenoyl-CoA + H2O = (9E)-octadecenoate + CoA + H(+)


name: Phosphorylation of HSF1 at Ser230 induces transactivation (Drosophila melanogaster)


name: 16beta,17beta-estriol 16-O-(beta-D-glucuronate) + H(+) + UDP => 16beta,17beta-estriol + UDP-alpha-D-glucuronate


name: Proton-coupled histidine and di-peptide cotransport (Saccharomyces cerevisiae)


name: butanoyl-CoA + H2O <=> adenosine 3',5'-bisphosphate + 2 H(+) + S-butanoyl-4'-phosphopantetheine


name: (2R,3S)-homoisocitrate = cis-homoaconitate + H2O


name: ATP + L-serine = ADP + H(+) + O-phospho-L-serine


name: (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein] => (2S)-2-methylbutanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: Loading of antigenic peptides on to class I MHC (Mus musculus)


name: ITPA hydrolyses ITP to IMP (Plasmodium falciparum)


name: ANO1 transports cytosolic Cl- to extracellular region (Rattus norvegicus)


name: CoA + H(+) + N-terminal N(alpha)-acetyl-L-prolyl-[protein] => acetyl-CoA + N-terminal L-prolyl-[protein]


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Drosophila melanogaster)


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Gallus gallus)


name: Semiquinone reacts with oxygen (Homo sapiens)


name: Active FLT3:GRB2 binds SOS1 (Homo sapiens)


name: GSK3 phosphorylates p-GLI3 (Gallus gallus)


name: codeine + NADP(+) = codeinone + H(+) + NADPH


name: 17-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: [phosphate](n+1) + AMP => [phosphate](n) + ADP


name: acetaldehyde + vanillin => (E)-isoeugenol + O2


name: (R)-2-hydroxyhexadecanoate + O2 <=> CO2 + H2O + pentadecanoate


name: E2F1 binds the CDK1 gene promoter (Homo sapiens)


name: Raf dimer inhibitors bind RAF heterodimers (Drosophila melanogaster)


name: Translocation of active caspase-8 to the mitochondrial membrane (Homo sapiens)


name: Deamination of C residues during synthesis of HIV-1 reverse transcript minus-strand (Homo sapiens)


name: 1,2,3-tripropanoylglycerol + H2O = dipropanoylglycerol + H(+) + propanoate


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Xenopus tropicalis)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Gallus gallus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + acetyl-CoA => 1-O-(1Z)-alkenyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + phosphate <=> alpha-D-galactose 1-phosphate + N-acetyl-D-glucosamine


name: MRN complex binds DNA double strand breaks (Schizosaccharomyces pombe)


name: Pellino ubiquitinates IRAK1 (Sus scrofa)


name: (9Z,12Z)-octadecadienoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine => 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA


name: alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + GDP + H(+)


name: KCND tetramer:KCNIP tetramer transport K+ from cytosol to extracellular region (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> (2E,6E,10E)-geranylgeranyl phosphate + H(+) + phosphate


name: (4R)-hydroxysphinganine + hexadecanoyl-CoA <=> CoA + H(+) + N-hexadecanoyl-(4R)-hydroxysphinganine


name: LDLR is bound by DAB2 and ARH (Mus musculus)


name: NOTCH1 HD+PEST domain mutants bind DLL1 (Homo sapiens)


name: a 5'-end ribonucleotide-tRNA(His) + ATP + GTP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Mus musculus)


name: coenzyme M + methyl-Co(III)-[methanol-specific corrinoid protein] => Co(I)-[methanol-specific corrinoid protein] + H(+) + methyl-coenzyme M


name: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH


name: H2O + L-2-aminopentanoate + O2 = 2-oxopentanoate + H2O2 + NH4(+)


name: SUMOylation of TOP1 with SUMO1 (Homo sapiens)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Sus scrofa)


name: 2-oxospirilloxanthin + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] => 2,2'-dioxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Bos taurus)


name: adenosine 2'-phosphate + H2O = adenosine + phosphate


name: Beta-catenin:TCF associates with BCL9 and PYGO (Mus musculus)


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Sus scrofa)


name: PAKs phosphorylate MLC (Drosophila melanogaster)


name: 10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate


name: L-lysine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) = L-lysine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: a neolactoside nLc4Cer + GDP-beta-L-fucose => a neolactoside IV(2)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: 7-dehydrodesmosterol + H(+) + NADPH = desmosterol + NADP(+)


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: 8-hydroxycopalyl diphosphate <=> (13R)-manoyl oxide + diphosphate


name: (1R,4S)-isodihydrocarvone + H(+) + NADH => (1R,2S,4S)-neoisodihydrocarveol + NAD(+)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Plasmodium falciparum)


name: PARVB interacts with Alpha-actinin (Canis familiaris)


name: 8-oxo-dAMP + H(+) + phosphate => 8-oxo-dADP + H2O


name: androst-4-ene-3,17-dione + H(+) + NADH => NAD(+) + testosterone


name: GDP-beta-L-fucose + L-seryl-[protein] = 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + GDP + H(+)


name: S-adenosyl-L-methionine + scutellarein 4'-methyl ether = ladanein + S-adenosyl-L-homocysteine


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Canis familiaris)


name: Recruitment of  RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Sus scrofa)


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Schizosaccharomyces pombe)


name: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 = 2 H2O + isopenicillin N


name: H2O2 + 2 L-ascorbate = 2 H2O + 2 monodehydro-L-ascorbate radical


name: 3-hydroxy-4-methylanthranilate + ATP + H(+) => 3-hydroxy-4-methylanthranilyl-5'-AMP + diphosphate


name: snRNP:Snurportin complex formation (Caenorhabditis elegans)


name: RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Gallus gallus)


name: chloride(in) + 2 Na(+)(in) + taurine(in) => chloride(out) + 2 Na(+)(out) + taurine(out)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Saccharomyces cerevisiae)


name: AH2 + menaquinone-9 <=> A + beta-dihydromenaquinone-9


name: Proteinase-activated receptors can bind thrombin (Canis familiaris)


name: 17beta-estradiol + AH2 + O2 => 6beta-hydroxyestradiol-17beta + A + H2O


name: propanoyl-CoA + succinate = propanoate + succinyl-CoA


name: PPARA gene expression is stimulated by EBF2 and PPARG and repressed by ZNF423 and NuRD (Homo sapiens)


name: Dissociation of CI from COS (Drosophila melanogaster)


name: RAS:GTP binds RAL GDS proteins (Caenorhabditis elegans)


name: 6alpha-hydroxycastasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxocastasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: AH2 + echinenone + O2 => 4'-hydroxyechinenone + A + H2O


name: PDCD1 binds PDCD1 inhibitors (Bos taurus)


name: (3R)-hydroxyeicosanoyl-CoA + NAD(+) <=> 3-oxoeicosanoyl-CoA + H(+) + NADH


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-(9Z-octadecaenoyl)-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Mus musculus)


name: PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Bos taurus)


name: CPT2 converts palmitoyl carnitine to palmitoyl-CoA (Bos taurus)


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate => 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate


name: Production of phagocyte oxygen radicals by NOX2 complex bound to RAC2:GTP (Canis familiaris)


name: taurine + tetradecanoyl-CoA <=> CoA + H(+) + N-tetradecanoyl-taurine


name: 3-alpha-D-mannopyranosyl-alpha-D-mannopyranose + UDP-alpha-D-xylose <=> 3-O-(6-O-alpha-D-xylosylphospho-alpha-D-mannopyranosyl)-alpha-D-mannopyranose + H(+) + UMP


name: Formation of dehydro-hydroxylysino-norleucine cross-links (Xenopus tropicalis)


name: Peroxynitrite is reduced by AhpE (Homo sapiens)


name: OCT1 transports organic cations into hepatic cells (Rattus norvegicus)


name: AP-2 directly binds some endocytic cargo (Caenorhabditis elegans)


name: Defective SLC24A5 does not exchange cytosolic 4Na+ for Golgi luminal Ca2+, K+ (Homo sapiens)


name: a (2E)-enoyl-CoA + H(+) + NADPH => a 2,3-saturated acyl-CoA + NADP(+)


name: PRKN binds p-S-Ub:MOM proteins (Schizosaccharomyces pombe)


name: SUMOylation of HDAC1 with SUMO1 (Sus scrofa)


name: SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Xenopus tropicalis)


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Saccharomyces cerevisiae)


name: (R)-lactate + a quinone <=> a quinol + pyruvate


name: botD LC cleaves target cell VAMP2 (Homo sapiens)


name: KCNJs transport K+ from the extracellular region to cytosol (Canis familiaris)


name: 7-methylmellein + 3 CO2 + 5 CoA + 4 H2O + 5 NADP(+) => acetyl-CoA + 9 H(+) + 4 malonyl-CoA + 5 NADPH


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Schizosaccharomyces pombe)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Canis familiaris)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Drosophila melanogaster)


name: NADP(+) + pregnan-21-ol => H(+) + NADPH + pregnan-21-al


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Sus scrofa)


name: H(+) + UDP + validamycin A => UDP-alpha-D-glucose + validoxylamine A


name: (S)-4-hydroxy-2-oxopentanoate = (2Z)-2-hydroxypenta-2,4-dienoate + H2O


name: FLT3 fusions phosphorylate GAB2 (Homo sapiens)


name: 2-demethylmenaquinol-8 + CO2 + diphosphate => 1,4-dihydroxy-2-naphthoate + all-trans-octaprenyl diphosphate + H(+)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: AFG3L2 binds mitochondrial inner membrane proteins (Danio rerio)


name: L-histidinol + NAD(+) = H(+) + L-histidinal + NADH


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Canis familiaris)


name: (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NH4(+) => (2Z,4E)-2-aminomuconate + H2O


name: tBID binds to inactive BAX protein (Mus musculus)


name: Hydrolysis of ATP and release of folded actin from CCT/TriC (Homo sapiens)


name: 17beta-hydroxy-androst-5-en-3-one + H(+) + NADH => androst-5-en-3beta,17beta-diol + NAD(+)


name: alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose => alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: Cleavage of 3-methyladenine by MPG glycosylase  (Bos taurus)


name: 2,6-dihydroxypseudooxynicotine + AH2 => 6-hydroxypseudooxynicotine + A + H2O


name: 1-propanol + butanoyl-CoA => CoA + propyl butanoate


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Dictyostelium discoideum)


name: TGFBR3 binding to GIPC1 (Canis familiaris)


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Rattus norvegicus)


name: D-alanine + H2O + NAD(+) = H(+) + NADH + NH4(+) + pyruvate


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Mus musculus)


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Drosophila melanogaster)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Sus scrofa)


name: 5-HT2 receptor can bind serotonin (Mus musculus)


name: Activation of JAK kinases (Canis familiaris)


name: (9Z,12Z)-octadecadienoyl-CoA + glycine => CoA + H(+) + N-(9Z,12Z-octadecadienoyl)-glycine


name: Aquaporin-4 passively transports water out of cell (Xenopus tropicalis)


name: D-xylotriono-1,5-lactone + H2O = D-xylotrionate + H(+)


name: (S)-canadine + H(+) + 2 O2 => berberine + 2 H2O2


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Homo sapiens)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Mus musculus)


name: 2-epi-5-epi-valiolone + ATP <=> 2-epi-5-epi-valiolone 7-phosphate + ADP + H(+)


name: 5-hydroxy-3-methyl-L-tyrosine + S-adenosyl-L-methionine = 5-hydroxy-3-methyl-O-methyl-L-tyrosine + H(+) + S-adenosyl-L-homocysteine


name: 3 A + FMN + H2O + L-glutamate + O2 <=> 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 3 AH2 + CO2 + H(+)


name: Dissociation of cytosolic HSF1:HSP90 complex (Schizosaccharomyces pombe)


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Mus musculus)


name: NAD(+) + prostaglandin A1 = 15-oxo-prostaglandin A1 + H(+) + NADH


name: Translocation of PKC theta to plasma membrane (Homo sapiens)


name: USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Rattus norvegicus)


name: 2-oxoglutarate + O2 + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO2 + succinate


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Mus musculus)


name: AP1G2 binds HGS and CHMP2A (Rattus norvegicus)


name: H(+) + oxidized [electron-transfer flavoprotein] + pentadecanoyl-CoA => (2E)-pentadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+) => D-methionine + H2O + O2


name: TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 (Homo sapiens)


name: H(+) + NADH + O2 + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+)


name: SLC2A5 transports fructose from extracellular region to cytosol (Rattus norvegicus)


name: Loading of acetylcholine in synaptic vesicles (Gallus gallus)


name: Zinc is an agonist of GPR39 (Rattus norvegicus)


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Schizosaccharomyces pombe)


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Sus scrofa)


name: SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Canis familiaris)


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Plasmodium falciparum)


name: CWO binds to cwo gene and represses transcription (Drosophila melanogaster)


name: (2S)-3-phenyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O => 2-dehydro-D-glucose + L-phenylalanine


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Sus scrofa)


name: ADP + estrone 3-sulfate(out) + H(+) + phosphate => ATP + estrone 3-sulfate(in) + H2O


name: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen


name: ERKs are inactivated by protein phosphatase 2A (Saccharomyces cerevisiae)


name: 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine <=> 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: PGM1:Mg2+ isomerises G6P to G1P (Rattus norvegicus)


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Rattus norvegicus)


name: 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA <=> 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA


name: Cleavage of p-STK3 (p-MST2) by caspase 3 (Rattus norvegicus)


name: (Z)-2-methylureidoacrylate + H(+) + H2O => (Z)-2-methylaminoacrylate + CO2 + NH4(+)


name: Interaction of Tie2 and Grb7 (Mus musculus)


name: an aliphatic alcohol + H(+) + pentanoate => H2O + pentanoate ester


name: a ribonucleoside 3',5'-bisphosphate + H2O <=> a ribonucleoside 5'-phosphate + phosphate


name: ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)


name: SUMOylation of DNMT3B with SUMO1 (Homo sapiens)


name: CDK4 phosphorylates RUNX2 (Drosophila melanogaster)


name: a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)


name: Furin cleaves pro-factor IX to factor IX (Xenopus tropicalis)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine


name: (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phosphocholine + cholesterol


name: Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Homo sapiens)


name: ATP + L-leucine + tRNA(Leu) => AMP + diphosphate + L-leucyl-tRNA(Leu)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine


name: a 3beta-hydroxy-4beta-hydroxymethyl-4alpha-methylsteroid + H2O + NAD(+) => a 3beta-hydroxy-4,4-dimethylsteroid + H(+) + NADH + O2


name: Loss of Rrn3 from RNA Polymerase I promoter escape complex (Gallus gallus)


name: 2-oxoglutarate + neomycin C => 6'''-deamino-6'''-oxoneomycin C + L-glutamate


name: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine


name: CDC42:GTP binds CBL:Beta-Pix (Drosophila melanogaster)


name: TIRAP binds PIP2-rich regions in the plasma membrane (Sus scrofa)


name: a quinone + L-quinate => 3-dehydroquinate + a quinol


name: Recruitment of Rad17-RFC complex to DNA (Rattus norvegicus)


name: 1beta-hydroxydeoxycholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => deoxycholate + O2 + reduced [NADPH--hemoprotein reductase]


name: a phenol + an aryl sulfate = a phenol + an aryl sulfate


name: extracellular phenylacetaldehyde-gated monoatomic ion channel activity


name: SLP-76 stimulates PLC gamma 2 (Canis familiaris)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Mus musculus)


name: H2O + S-methyl-5'-thioadenosine = 5-(methylsulfanyl)-D-ribose + adenine


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Rattus norvegicus)


name: Loss of SAR1B GTPase (Schizosaccharomyces pombe)


name: LIN28 binds POU5F1 (OCT4) mRNA (Homo sapiens)


name: glycyl-L-proline(in) + H(+)(in) => glycyl-L-proline(out) + H(+)(out)


name: GRB2:SOS1 binds to HBEGF:p-Y-EGFR (Canis familiaris)


name: L-iditol + NAD(+) => H(+) + keto-L-sorbose + NADH


name: 2-acyl LPE is acylated to PE by LPEAT (Dictyostelium discoideum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(9Z-octadecenoyl) ethanolamine = (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-[(9Z)-octadecenoylamino]ethyl (9Z)-octadecenoate


name: Exocytosis of specific granule membrane proteins (Bos taurus)


name: Recruitment of LIG3:XRCC1 complex to the site of repair by POLB (Bos taurus)


name: PCK1 phosphorylates OA to yield PEP (Dictyostelium discoideum)


name: 2 2-hexadecanoyl-sn-glycero-3-phosphocholine => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADPH = all-trans-lycopaoctaene + 2 diphosphate + NADP(+)


name: 3-dehydro-D-glucose + puerarin <=> 3''-dehydropuerarin + D-glucose


name: CBL ubiquitinates Sprouty (Xenopus tropicalis)


name: FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: IFN alpha/beta binds to IFNAR2 (Mus musculus)


name: 1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + H(+) + hexanoate


name: ATP + Fe(3+)(out) + H2O => ADP + Fe(3+)(in) + H(+) + phosphate


name: [(1->2)-beta-D-glucosyl](n) + a D-glucoside = [(1->2)-beta-D-glucosyl](n-1) + a beta-D-glucosyl-(1->2)-D-glucoside


name: (7Z,10Z,13Z,16Z,19Z)-3-oxodocosapentaenoyl-CoA + H(+) + NADPH <=> (3R)-hydroxy-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + NADP(+)


name: Elongation of Extended Telomeric Chromosome End (Homo sapiens)


name: FABP5 dissociates from RXRA:PPARD:atRA (Caenorhabditis elegans)


name: SPHK2 binds SPHK2 inhibitors (Rattus norvegicus)


name: SUMOylation of TOP1 with SUMO1 (Xenopus tropicalis)


name: 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Caenorhabditis elegans)


name: (E)-2-methylpropanal oxime + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylpropanenitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: "ferredoxin--NAD(P)(+) reductase (naphthalene dioxygenase ferredoxin-specific)"


name: (9S,13S,15Z)-12-oxophyto-10-15-dienoate + ATP + CoA <=> (10Z,15Z)-12-oxophytodienoyl-CoA + AMP + diphosphate


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)


name: RHOD translocates to the Golgi membrane (Drosophila melanogaster)


name: 16beta,17beta-estriol + UDP-alpha-D-glucuronate => 16beta,17beta-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: very-low-density lipoprotein particle receptor activity


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Rattus norvegicus)


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Mus musculus)


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Homo sapiens)


name: kaempferol 3-O-beta-D-glucoside + malonyl-CoA <=> CoA + kaempferol 3-O-(6-O-malonyl-beta-D-glucoside)


name: indolin-2-one + O2 + reduced [NADPH--hemoprotein reductase] => 3-hydroxyindolin-2-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + L-xylulose = ADP + H(+) + L-xylulose 5-phosphate


name: SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Mus musculus)


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate <=> 2-oxoglutarate + GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: alpha-D-mannosyl-(1->3)-alpha-D-galactosyl-diphospho-di-trans,octa-cis-undecaprenol + GDP-alpha-D-mannose => alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Xenopus tropicalis)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: Active G alpha (q) binds RGS proteins (Drosophila melanogaster)


name: CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome (Drosophila melanogaster)


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Homo sapiens)


name: Degradation of multiubiquitinated Cyclin B (Homo sapiens)


name: Activated MAPKs phosphorylate BRAF (Plasmodium falciparum)


name: Thrombin-activated PARs activate Gq (Homo sapiens)


name: Autophosphorylation of BTK/ITK (Mus musculus)


name: SLC36A4 transports extracellular L-Pro to the cytosol (Drosophila melanogaster)


name: 4-methylsulfanyl-2-oxobutanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine


name: a 1,2-diacyl-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine


name: uridine(65) in tRNA = pseudouridine(65) in tRNA


name: Metallochaperone inserts Cu2+ into MT-CO1 (Caenorhabditis elegans)


name: ADP + D-ribose 5-phosphate + H(+) => ADP-D-ribose + phosphate


name: SREBP1A,1C,2 translocates to the nucleus (Bos taurus)


name: a ganglioside GT3 (d18:1(4E)) + CMP + H(+) => a ganglioside GD3 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Gallus gallus)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Drosophila melanogaster)


name: 16-hydroxytabersonine + S-adenosyl-L-methionine <=> 16-methoxytabersonine + H(+) + S-adenosyl-L-homocysteine


name: PMM1,2 isomerise Man6P to Man1P (Drosophila melanogaster)


name: SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) (Caenorhabditis elegans)


name: beta-D-glucosyl-(1->3)-D-glucose + phosphate <=> alpha-D-glucose 1-phosphate + D-glucose


name: Hh processing variants are translocated to the cytosol in a VCP-dependent manner (Homo sapiens)


name: STAT binds to the mutant PDGFRA receptor (Homo sapiens)


name: Caspase mediated cleavage of vimentin at IDVD (259) (Canis familiaris)


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Xenopus tropicalis)


name: Tropoelastin forms aggregate globules (Gallus gallus)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Mus musculus)


name: ATP + L-homoserine <=> ADP + H(+) + O-phospho-L-homoserine


name: Co-precorrin-6B + S-adenosyl-L-methionine => Co-precorrin-7 + CO2 + S-adenosyl-L-homocysteine


name: an N(2)-acyl-L-glutamine + H2O = a carboxylate + L-glutamine


name: Basigin binds Mannose-carrying cell recognition molecules (Xenopus tropicalis)


name: 4-O-deacetylvindoline + acetyl-CoA => CoA + vindoline


name: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol (Canis familiaris)


name: ADP + H(+) + N-acetyl-L-aspartyl-L-glutamate(out) + phosphate => ATP + H2O + N-acetyl-L-aspartyl-L-glutamate(in)


name: ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC (Rattus norvegicus)


name: an (E)-omega-(methylsulfanyl)-alkanal oxime + glutathione + O2 + reduced [NADPH--hemoprotein reductase] <=> an S-[(1E)-1-(hydroxyimino)-omega-(methylsulfanyl)alkyl]-L-glutathione + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Arachidonate  is converted to 12-oxoETE by ALOX12 (Danio rerio)


name: DNA polymerase epsilon binds at the origin (Xenopus tropicalis)


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Homo sapiens)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Gallus gallus)


name: Elongation Of The Telomeric Chromosome End (Homo sapiens)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Mus musculus)


name: AMPK (complex) phosphorylates ULK1 (complex) (Canis familiaris)


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Sus scrofa)


name: 5-(3,3'-dimethylguanidino)-2-oxopentanoate + L-alanine => N(omega),N('omega)-dimethyl-L-arginine + pyruvate


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose => beta-D-Gal-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: a 1,3-diacylglycerol + H2O <=> a 1-acyl-sn-glycerol + a fatty acid + H(+)


name: GalNAc is transferred onto 3a (Homo sapiens)


name: Activation of Ca-permeable Kainate receptors (Caenorhabditis elegans)


name: Isopentenyl pyrophosphate rearranges to dimethylallyl pyrophosphate (Rattus norvegicus)


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + N-(32-hydroxydotriacontenoyl)-sphing-4-enine <=> a diacylglycerol + an N-(32-(9Z,12Z-octadecadienoyloxy)-dotriacontenoyl)-sphing-4-enine


name: a 1,3-diacyl-sn-glycerol + H2O => a fatty acid + a monoacylglycerol + H(+)


name: Sulfite is oxidized to sulfate (Homo sapiens)


name: MSL acetylates histone H4 (Homo sapiens)


name: 3-oxo-(7Z-hexadecenoyl)-CoA + CoA <=> (5Z)-tetradecenoyl-CoA + acetyl-CoA


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: D-galactose + NADP(+) => D-galactono-1,5-lactone + H(+) + NADPH


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-valine + O2 = (2S)-3-methyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]butanoate + H(+) + H2O2


name: AFG3L2 degrades mitochondrial matrix proteins (Mus musculus)


name: 3 H(+) + hexanoyl-CoA + 3 malonyl-CoA => 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Drosophila melanogaster)


name: HSPG2 (perlecan) degradation by MMP14, MMP15 (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + an N-acylethanolamine <=> 2-(acylamino)ethyl fatty acid + a monoacyl-sn-glycero-3-phosphocholine


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Sus scrofa)


name: ALOX12 oxidises LTA4 to LXB4 (Bos taurus)


name: 2,6-dichlorohydroquinone + FADH2 + O2 => 2-chloro-6-hydroxy-1,4-benzoquinone + chloride + FAD + 2 H(+) + H2O


name: TPX2 binds AURKA at centrosomes (Xenopus tropicalis)


name: calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential


name: NCOA2(869-1464) binds KAT6A(1-1118) (Gallus gallus)


name: H2O + methylamine + 2 oxidized [amicyanin] => formaldehyde + 2 H(+) + NH4(+) + 2 reduced [amicyanin]


name: MET phosphorylates PTK2 (Canis familiaris)


name: Formation of the PINCH-ILK-parvin complex (Canis familiaris)


name: Activated FGFR4 phosphorylates FRS2 (Drosophila melanogaster)


name: Isomerization of 25(R) DHCA-CoA to 25(S) DHCA-CoA (Drosophila melanogaster)


name: Activated FGFR4 binds PLCG1 (Drosophila melanogaster)


name: Interaction of IQGAP1 with nephrin (Rattus norvegicus)


name: MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Sus scrofa)


name: 7-chloro-L-tryptophan + chloride + FADH2 + O2 => 6,7-dichloro-L-tryptophan + FAD + 2 H2O


name: Metallochaperone inserts 2Cu2+ into MT-CO2 (Homo sapiens)


name: 13-dihydrocarminomycin + H2O + NADP(+) => 13-deoxycarminomycin + H(+) + NADPH + O2


name: FASL:FAS Receptor Trimer:FADD complex binds pro-Caspase-8 (Mus musculus)


name: SUMOylation of HIPK2 with SUMO1 (Sus scrofa)


name: [(1->4)-alpha-D-galacturonosyl](n) + n H(+) + n methanol => [(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O


name: RHOD auto-activates (Saccharomyces cerevisiae)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Xenopus tropicalis)


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Sus scrofa)


name: H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate


name: "N-acetylmuramic acid 6-phosphate etherase"


name: WHSC1 binds DNA DSBs (Rattus norvegicus)


name: RCC1 stimulates GDP to GTP exchange on RAN (Canis familiaris)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Mus musculus)


name: FAD(out) + NAD(+)(in) <=> FAD(in) + NAD(+)(out)


name: PTK6 phosphorylates CBL (Rattus norvegicus)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Xenopus tropicalis)


name: RHOC translocates to the endoplasmic reticulum membrane (Bos taurus)


name: H2O + O2 + spermine = H2O2 + N-(3-aminopropyl)-4-aminobutanal + propane-1,3-diamine


name: an L-alpha-amino acid + H2O + NAD(+) = a 2-oxocarboxylate + H(+) + NADH + NH4(+)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Mus musculus)


name: CTP(in) + GMP(out) => CTP(out) + GMP(in)


name: PA is dephosphorylated to DAG by LPIN (Dictyostelium discoideum)


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: PTPN1 and PTPN2 dephosphorylate MET (Sus scrofa)


name: RAP1A exchanges GDP for GTP (Homo sapiens)


name: PITPNM1,2,3 exchange PI for PA (Sus scrofa)


name: mTORC2 phosphorylates AKT1 on serine-473 (Mus musculus)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Homo sapiens)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Schizosaccharomyces pombe)


name: H2O + N(6)-acetyl-L-lysyl-[alpha-tubulin] = acetate + L-lysyl-[alpha-tubulin]


name: SLC25A1 transports di-/tri-peptides and peptide-like drugs (Dictyostelium discoideum)


name: HIPK2 phosphorylates MECP2 (Homo sapiens)


name: archaetidylserine + H(+) <=> archaetidylethanolamine + CO2


name: Trimerization of cytosolic HSF1 (Schizosaccharomyces pombe)


name: Fe(2+)(in) + 2 hydrogencarbonate(in) => Fe(2+)(out) + 2 hydrogencarbonate(out)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Saccharomyces cerevisiae)


name: RXRA binds ligands (Drosophila melanogaster)


name: Activation of THIK (Saccharomyces cerevisiae)


name: N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA = CoA + H(+) + N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein]


name: Formation of clathrin coated vesicle (Bos taurus)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO1 (Mus musculus)


name: (2E,6E)-farnesyl diphosphate => (+)-exo-beta-bergamotene + diphosphate


name: NAD(+) + ursodeoxycholate <=> 7-oxolithocholate + H(+) + NADH


name: acetyl-CoA + CMP-N-acetyl-beta-neuraminate <=> CMP-N-beta-acetyl-7-O-acetylneuraminate + CoA


name: CHRM1,3,5 bind acetylcholine (Gallus gallus)


name: NOTCH2 coactivator complex binds HES5 promoter (Homo sapiens)


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Drosophila melanogaster)


name: acetophenone + 2 ATP + H2O + hydrogencarbonate <=> 3-oxo-3-phenylpropanoate + 2 ADP + 2 H(+) + 2 phosphate


name: (+)-alpha-tocopherol + O2 + reduced [NADPH--hemoprotein reductase] = 13-hydroxy-alpha-tocopherol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (3S)-1,2-diazinane-3-carboxylate + H(+) + H2O => N(5)-hydroxy-L-ornithine


name: GGT dimers hydrolyse GSH (Rattus norvegicus)


name: Acitretin binds to RAR:RXR (Rattus norvegicus)


name: dTDP-6-deoxy-beta-L-talose + NAD(+) => dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADH


name: ARL2:GTP bind PDE6D on KRAS4B (Caenorhabditis elegans)


name: H2O + N(6)-octanoyl-L-lysyl-[protein] + NAD(+) => 2''-O-octanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP (Homo sapiens)


name: cortisone + O2 + reduced [NADPH--hemoprotein reductase] => 6beta-hydroxycortisone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + cytidine(34) in tRNA(Ile2) + L-lysine <=> AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)


name: SERPINA6 binds PREDN (Drosophila melanogaster)


name: Trehalose-6-phosphate is hydrolyzed to trehalose (Mycobacterium tuberculosis)


name: TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Gallus gallus)


name: (R,R)-chrysanthemyl diphosphate + diphosphate => 2 dimethylallyl diphosphate


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate = colnelenate + H2O


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] = 6alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Danio rerio)


name: (+)-car-3-ene + diphosphate => (2E)-geranyl diphosphate


name: (Z)-glucobrassicin + adenosine 3',5'-bisphosphate + H(+) => (Z)-indolylmethyl desulfoglucosinolate + 3'-phosphoadenylyl sulfate


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Caenorhabditis elegans)


name: RNF181 polyubiquinates BCL10 (Canis familiaris)


name: PKN1 stimulates association of AR with NCOA2 (Sus scrofa)


name: factor Va + factor Xa -> Va:Xa complex (prothrombinase) (Danio rerio)


name: 5-methyl-3-oxohexanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxy-5-methylhexanoyl-[ACP] + NADP(+)


name: choline + NAD(+) => betaine aldehyde + H(+) + NADH


name: NADPH + O2 + putrescine <=> H2O + N-hydroxyputrescine + NADP(+)


name: GRB2:SOS interacts with p-KIT (Rattus norvegicus)


name: H(+)(in) + L-asparagine(out) + Na(+)(out) <=> H(+)(out) + L-asparagine(in) + Na(+)(in)


name: 2-oxoglutarate + 2 H(+) + NADH => 2,5-dioxopentanoate + H2O + NAD(+)


name: 2-acyl LPC is acylated to PC by LPCAT (Drosophila melanogaster)


name: Translocation of NuMA to the centrosomes (Bos taurus)


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Drosophila melanogaster)


name: 5-diphospho-1D-myo-inositol 1,3,4,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + H(+) + phosphate


name: CHEK1 phosphorylates RAD51 (Drosophila melanogaster)


name: a ganglioside GM3 + CMP + H(+) => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + CMP-N-acetyl-beta-neuraminate


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Homo sapiens)


name: 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3] + succinate


name: (R)-carnitine(in) + 2-oxoglutarate(out) => (R)-carnitine(out) + 2-oxoglutarate(in)


name: glycyl-L-glutamate(in) + 2 H(+)(in) => glycyl-L-glutamate(out) + 2 H(+)(out)


name: Expression of ANGPTL3 regulated by NR1H2 or NR1H3 (Homo sapiens)


name: beta-alanine(out) + chloride(out) + 2 Na(+)(out) <=> beta-alanine(in) + chloride(in) + 2 Na(+)(in)


name: L-idonate + NADP(+) <=> 5-dehydro-D-gluconate + H(+) + NADPH


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Mus musculus)


name: (2S)-3-(4-hydroxyphenyl)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H(+) + H2O2 => N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2


name: an aromatic aldehyde + H2O + O2 => an aromatic carboxylate + H(+) + H2O2


name: Association of RPA complexes with ssDNA at resected DNA DSBs (Rattus norvegicus)


name: anthranilate + 2 H(+) + NADPH + O2 => 2,3-dihydroxybenzoate + NADP(+) + NH4(+)


name: EP300 is recruited to MYC and BCL2 genes (Homo sapiens)


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: [translation elongation factor 2]-phosphate + ADP + H(+) => [translation elongation factor 2] + ATP


name: PTK6 phosphorylates SFPQ (Rattus norvegicus)


name: Formation of the inner ring of the 20S core particle of the 26S proteasome (Homo sapiens)


name: ENPP7 hydrolyzes sphingomyelin (Xenopus tropicalis)


name: ADD1:ADD2 binds DMTN (Drosophila melanogaster)


name: (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O = resolvin E1


name: D-alanine + L-glutamine => gamma-L-glutamyl-D-alanine + NH4(+)


name: 4 Fe(III)-[cytochrome c] + H2O + hydroxylamine => 4 Fe(II)-[cytochrome c] + 5 H(+) + nitrite


name: NSF and SNAPs bind the cis-SNARE at the Golgi (Canis familiaris)


name: ATM recognizes H2AFX-Nucleosomes (Saccharomyces cerevisiae)


name: Hyperphosphorylated IRAK1 associates with TRAF6 (Sus scrofa)


name: deoxynogalonate + O2 => H(+) + H2O + nogalonate


name: 2 a quinone + H(+) + NADPH <=> 2 a 1,4-benzosemiquinone + NADP(+)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Drosophila melanogaster)


name: HRH3 binds pitosilant (Rattus norvegicus)


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Rattus norvegicus)


name: (E)-4-O-(beta-D-glucuronosyl)-ferulate + H(+) + UDP => (E)-ferulate + UDP-alpha-D-glucuronate


name: a fatty acyl-CoA + H2O => a fatty acid + CoA + H(+)


name: L-homocysteine + NH4(+) + pyruvate => H2O + L,L-cystathionine


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Canis familiaris)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O <=> 1-O-alkyl-sn-glycero-3-phosphate + a fatty acid + H(+)


name: MTRR reduces cob(II)alamin to meCbl (Mus musculus)


name: (2E)-geranyl diphosphate = (-)-car-3-ene + diphosphate


name: IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Sus scrofa)


name: USP47 deubiquitinates POLB (Homo sapiens)


name: AMP + beta-alanyl-dopamine + diphosphate + H(+) => ATP + beta-alanine + dopamine


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Danio rerio)


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O = (14R,15R)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate


name: 16alpha,17alpha-dihydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase]


name: benzaldehyde + H2O + O2 = benzoate + H(+) + H2O2


name: Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Gallus gallus)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Saccharomyces cerevisiae)


name: an N-acylsphing-4-enine(out) => an N-acylsphing-4-enine(in)


name: oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor


name: L-seryl-[EGF-like domain protein] + UDP-alpha-D-glucose <=> 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: carbaryl + H(+) + H2O = 1-naphthol + CO2 + methylamine


name: [(1->2)-beta-D-glucosyl](n+1) + H(+) + UDP => [(1->2)-beta-D-glucosyl](n) + UDP-alpha-D-glucose


name: (2E,6E)-farnesyl diphosphate <=> alpha-longipinene + diphosphate


name: 7alpha-hydroxy-3-oxochol-4-en-24-oate <=> 3-oxochola-4,6-dien-24-oate + H2O


name: BLT receptors can bind LTB4 (Danio rerio)


name: AKT1 phosphorylates NOTCH4 (Homo sapiens)


name: Reduction of disulphide bonds in MHC II antigens (Xenopus tropicalis)


name: a 2-acylglycerol + phosphate => a 2-acyl-sn-glycerol 3-phosphate + H2O


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Rattus norvegicus)


name: 2 H2O + levopimaradienal + NADP(+) => H(+) + levopimaradienol + NADPH + O2


name: Interleukin-1 receptor type 1: Interleukin 1 binds Interleukin-1 receptor accessory protein, membrane associated isoform (Mus musculus)


name: 2 caldariellaquinol + n H(+)(in) + O2 => 2 caldariellaquinone + n H(+)(out) + 2 H2O


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + phosphate


name: D-cellobiono-1,5-lactone + H2O => 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)


name: misspliced mutants of LRP5 support enhanced beta-catenin-dependent signaling (Homo sapiens)


name: SUMOylation of TDG with SUMO2,3 (Sus scrofa)


name: Thrombin-activated PARs binds G-protein Gq (Xenopus tropicalis)


name: ATP + H(+) + hexanoate + NADPH = AMP + diphosphate + hexanal + NADP(+)


name: IL20 binds IL20RA:JAK1:IL20RB (Sus scrofa)


name: aminoacetone + CO2 + NADPH => L-allo-threonine + NADP(+)


name: 2-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) <=> methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + salicylate


name: Nuclear DUSPs dephosphorylate MAPKs (Gallus gallus)


name: Defective GLB1 does not hydrolyse linker chain(2) (Homo sapiens)


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Plasmodium falciparum)


name: Formation of the pre-incision complex in GG-NER (Sus scrofa)


name: a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + H(+) + UDP => a flavonol 3-O-beta-D-glucoside + UDP-alpha-D-glucose


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 => (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: Cleavage of uracil by MBD4 glycosylase (Gallus gallus)


name: a quinone + 5 H(+)(in) + NADPH = a quinol + 4 H(+)(out) + NADP(+)