name: a 1,4-lactone + H2O => a 4-hydroxyacid + H(+)


name: 3-demethylubiquinol-10 + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + ubiquinol-10


name: 15-methylhexadecasphing-4-enine 1-phosphate => (2E)-13-methyltetradecenal + phosphoethanolamine


name: NICD2 traffics to the nucleus (Homo sapiens)


name: IL34 dimer:SDC1 binds CSF1R (Homo sapiens)


name: 3-hydroxyisopentadecanoyl-CoA + NADP(+) = 3-oxoisopentadecanoyl-CoA + H(+) + NADPH


name: 3''-dehydroisoorientin <=> 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: 4-coumaroyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 4 CO2 + 4 CoA + trans-resveratrol


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Rattus norvegicus)


name: a 3-dehydro-D-guloside => a 3-dehydro-D-glucoside


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)


name: 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-O-octadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: carnosine(out) + H(+)(out) = carnosine(in) + H(+)(in)


name: 2-hydroxybutanoate + NADP(+) => 2-oxobutanoate + H(+) + NADPH


name: (2E,6E,10E)-geranylgeranyl diphosphate + bacteriochlorophyllide a + H(+) <=> diphosphate + geranylgeranyl-bacteriochlorophyllide a


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Caenorhabditis elegans)


name: (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O <=> (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: Formation of the Flap Intermediate (Schizosaccharomyces pombe)


name: 7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA => 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine


name: carcinine transmembrane transporter activity


name: H(+) + ketocytochalasin + NADPH + O2 <=> H2O + iso-precytochalasin + NADP(+)


name: Integrin alphaIIb beta3 activation (Homo sapiens)


name: H(+) + NADPH + testosterone => 17beta-hydroxy-5alpha-androstan-3-one + NADP(+)


name: glutathione + thiosulfate => H(+) + S-sulfanylglutathione + sulfite


name: 1-acyl LPS is acylated to PS by LPSAT (Plasmodium falciparum)


name: a 2,3-diacyl-sn-glycerol + H2O <=> a 2-acylglycerol + a fatty acid + H(+)


name: Recruitment of HDAC1 by p107 (RBL1) (Bos taurus)


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Mus musculus)


name: demethyllactenocin + S-adenosyl-L-methionine => H(+) + lactenocin + S-adenosyl-L-homocysteine


name: Serine phosphorylation of STATs (Homo sapiens)


name: acetyl-CoA + dopamine = CoA + H(+) + N-acetyl-dopamine


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Gallus gallus)


name: 2-isopropylmaleate + H2O => (2S)-2-isopropylmalate


name: cAMP induces dissociation of inactive PKA tetramers (Bos taurus)


name: Dephosphorylation of AKT by PP2A (Saccharomyces cerevisiae)


name: (E)-cinnamoyl-CoA + (R)-3-phenyllactate => (E)-cinnamate + (R)-3-phenyllactoyl-CoA


name: SUMOylation of TOP2B with SUMO1 (Homo sapiens)


name: BAG6:GET4:UBL4A binds mislocalized membrane protein:SGTA and ASNA1:ATP (Homo sapiens)


name: SERPINA6 binds PREDL (Drosophila melanogaster)


name: RHOD binds effectors at the endosome membrane (Canis familiaris)


name: p-S363,S380,T573 RS6K translocates to the nucleus (Canis familiaris)


name: alpha-D-glucose 6-phosphate => beta-D-fructose 6-phosphate


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Schizosaccharomyces pombe)


name: chloride(out) + 2 hydrogencarbonate(in) = chloride(in) + 2 hydrogencarbonate(out)


name: Mcm2-7 is phosphorylated by DDK (Sus scrofa)


name: 2-deoxy-D-ribose 5-phosphate => acetaldehyde + D-glyceraldehyde 3-phosphate


name: secondary active p-aminobenzoyl-glutamate transmembrane transporter activity


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Canis familiaris)


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Canis familiaris)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Danio rerio)


name: a globoside Gb4Cer + UDP-alpha-D-galactose <=> a globoside NOR1 + H(+) + UDP


name: (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone => (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol


name: Defective PNP does not convert (deoxy)inosine to hypoxanthine and (deoxy)ribose (Homo sapiens)


name: NICD2 binds RBPJ and MAML in the nucleus (Homo sapiens)


name: diphosphate + dTDP-alpha-D-glucose => alpha-D-glucose 1-phosphate + dTTP + H(+)


name: CL transports from the ER to the IM (Homo sapiens)


name: Translocation and activation of PKC alpha in response to WNT signaling (Homo sapiens)


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl derivative + H(+) + UDP


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Sus scrofa)


name: Formation of the PINCH-ILK-parvin complex (Homo sapiens)


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + ATP = 3-diphospho-1D-myo-inositol 1,2,4,5-tetrakisphosphate + ADP


name: D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate (Drosophila melanogaster)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Bos taurus)


name: H2O + N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein] = N(alpha)-acetyl-L-methionine + N-terminal L-aspartyl-[protein]


name: 2 L-ascorbate + N-decanoylglycine + O2 => H2O + 2 monodehydro-L-ascorbate radical + N-decanoyl-(2S)-hydroxyglycine


name: B3GALT4 transfers Gal to gangliosides (Sus scrofa)


name: AWAT2 transfers PALM from PALM-CoA to HXOL, forming palmityl palmitate ester (Saccharomyces cerevisiae)


name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity


name: BTNL2 binds activated T cells surface (Gallus gallus)


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Homo sapiens)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Canis familiaris)


name: MAGED1 binds NPAS4 (Drosophila melanogaster)


name: CYP4F12 18-hydroxylates ARA (Bos taurus)


name: TNFAIP8 proteins transfer PI(4,5)P2, PI(3,4,5)P3 from cytosolic vesicles to plasma membrane (Homo sapiens)


name: thymine or uracil + 2-deoxy-D-ribose 1-phosphate <=> thymidine or deoxyuridine + orthophosphate [TYMP] (Homo sapiens)


name: D-ribose 5-phosphate + hypoxanthine => H2O + IMP


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Dictyostelium discoideum)


name: BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 (Homo sapiens)


name: HPN heterodimer cleaves pro-HGF to form HGF dimer (Bos taurus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA <=> 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: a cis-3-alkyl-4-alkyloxetan-2-one => a cis-alkene + CO2


name: Phosphorylated MAPKs phosphorylate ATF-2 (Xenopus tropicalis)


name: diphosphate + pppGp(2'-5')A => ATP + GTP


name: Defective GUSB does not hydrolyse GlcA-β1,3-GlcNAc (Homo sapiens)


name: lithocholate + NAD(+) = 3-oxo-5beta-cholan-24-oate + H(+) + NADH


name: GSTO1 dimer reduces methylarsonate to methylarsonite (Canis familiaris)


name: glutarate(in) + xanthurenate(out) <=> glutarate(out) + xanthurenate(in)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Sus scrofa)


name: 4 H(+) + 3 NADH + sulfite => 3 H2O + hydrogen sulfide + 3 NAD(+)


name: a 2-acyl-sn-glycero-3-phosphocholine + a hepta-acyl lipid A => a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid A


name: ALPK1 phosphorylates TIFA (Gallus gallus)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Xenopus tropicalis)


name: ABCF1 binds EIF2 (Schizosaccharomyces pombe)


name: H(+) + NADH + O2 + pyrrole-2-carboxylate => 5-hydroxypyrrole-2-carboxylate + H2O + NAD(+)


name: GLP1R binds GLP1R agonists (Homo sapiens)


name: L-arginine(out) + L-leucine(in) => L-arginine(in) + L-leucine(out)


name: ALOX5 binds ALOX5 inhibitors (Rattus norvegicus)


name: 2-oxobutanoate + L-tyrosine => (2S)-2-aminobutanoate + 3-(4-hydroxyphenyl)pyruvate


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Rattus norvegicus)


name: (3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) = [(3R)-hydroxybutanoate](n+1) + CoA


name: cytochrome P450 dependent 16beta-hydroxy-beta-amyrin epoxidase activity


name: PPM1A protein phosphatase binds phosphorylated SMAD2/3 (Bos taurus)


name: (R)-4'-phosphopantothenate + CTP + L-cysteine => CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine


name: 3,4-dinitrotoluene + NADH + O2 <=> 4-methyl-6-nitrocatechol + NAD(+) + nitrite


name: 2,4,6-trichlorophenol + FADH2 + O2 => 2-chloro-6-hydroxy-1,4-benzoquinone + 2 chloride + FAD + 3 H(+)


name: SHP1 and SHP2 bind the common beta chain (Canis familiaris)


name: DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Gallus gallus)


name: IGF2BP1 binds specific RNAs (Homo sapiens)


name: MYD88 binds to TUB (Drosophila melanogaster)


name: CDO1:Fe2+ oxidises L-Cys to 3-Sulfinoalanine (Drosophila melanogaster)


name: a mannosylinositol-1-phosphophytoceramide + GDP + H(+) => an inositol-1-phosphophytoceramide + GDP-alpha-D-mannose


name: 3,4-dihydroxybenzoate + 2 bromide + 5 H(+) + 2 NADPH + 2 O2 <=> 3,5-dibromobenzene-1,2-diol + CO2 + 4 H2O + 2 NADP(+)


name: 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+) + octadecanoate


name: 7beta-hydroxycholesterol(in) + ATP + H2O => 7beta-hydroxycholesterol(out) + ADP + H(+) + phosphate


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Mus musculus)


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Homo sapiens)


name: cytosine(in) + H(+)(in) <=> cytosine(out) + H(+)(out)


name: H(+) + H2O + oryzalexin D + oxidized [NADPH--hemoprotein reductase] => ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: USP45 deubiquitinates ERCC1 (Danio rerio)


name: ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Xenopus tropicalis)


name: STUB1 ubiquitinates RIPK3 at K55, K363 (Canis familiaris)


name: 1,2,3-tri-(12R-hydroxy-9Z-octadecenoyl)-glycerol + CoA => (12R)-hydroxy-(9Z)-octadecenoyl-CoA + 1,2-di-(12R-hydroxy-9Z-octadecenoyl)-sn-glycerol


name: Calcineurin binds NFATC1,2,3 (Drosophila melanogaster)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphoglycerol + H2O => (9Z)-octadecenoate + a 2-acyl-sn-glycero-3-phosphoglycerol + H(+)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Canis familiaris)


name: aminoacetaldehyde + CO2 + NADPH => L-serine + NADP(+)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Mus musculus)


name: H2O2 oxidises ferrohemoglobin to MetHb (Xenopus tropicalis)


name: CoA + hexadecanal + NAD(+) => H(+) + hexadecanoyl-CoA + NADH


name: a primary amine + S-adenosyl-L-methionine = a methylated primary amine + H(+) + S-adenosyl-L-homocysteine


name: Heterodimerization of CEACAMs (Rattus norvegicus)


name: DNA-PKcs autophosphorylates (Sus scrofa)


name: hydrolase activity, acting on acid carbon-phosphorus bonds


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Rattus norvegicus)


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Saccharomyces cerevisiae)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Sus scrofa)


name: (S)-lactate(in) + citrate(out) <=> (S)-lactate(out) + citrate(in)


name: beta-L-Ara4N-lipid A (E. coli) + di-trans,octa-cis-undecaprenyl phosphate => 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A (E. coli)


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Mus musculus)


name: 4 H(+) + 5 malonyl-CoA => 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + 5 CoA + H2O


name: L-lysyl-[protein] + 3 S-adenosyl-L-methionine <=> 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: SULT1A1 dimer sulfonates NHABP (Danio rerio)


name: (2R)-3-phosphoglycerate + ADP-alpha-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+)


name: 2-oxoglutarate + [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate <=> [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + L-glutamate


name: Formation of Cyclin B:Cdc2 complexes (Drosophila melanogaster)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Caenorhabditis elegans)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: [(1->4)-beta-D-xylan](n) + UDP-alpha-D-xylose = [(1->4)-beta-D-xylan](n+1) + H(+) + UDP


name: Defective PAPSS2 does not transfer SO4(2-) group to ATP to form APS (Homo sapiens)


name: 3-hydroxypyruvate + D-glyceraldehyde <=> (3R,4S,5R)-3,4,5,6-tetrahydroxy-2-oxohexanoate


name: Dystroglycan binds AGRN and HSPG2 (Homo sapiens)


name: gibberellin A24 + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => gibberellin A15 + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: (S)-acetoin + H(+) + NADH => (S,S)-butane-2,3-diol + NAD(+)


name: Internalization of receptor bound antigen into clathrin coted vesicles (Canis familiaris)


name: ADP + H(+) + N-phosphotaurocyamine => ATP + taurocyamine


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Canis familiaris)


name: uracil transmembrane transporter activity


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Schizosaccharomyces pombe)


name: a plastoquinol + n H(+)(out) + NAD(+) => a plastoquinone + (n+1) H(+)(in) + NADH


name: NTP Binds Active Site of RNA Polymerase II (Bos taurus)


name: H(+) + NADH + O2 + vanillate => 3,4-dihydroxybenzoate + formaldehyde + H2O + NAD(+)


name: AMP + CoA + diphosphate + 2 H(+) + tenuazonic acid => acetoacetyl-CoA + ATP + L-isoleucine


name: p-FRS2:CRKL binds C3G (Canis familiaris)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Drosophila melanogaster)


name: COPI vesicle uncoating at the ER (Danio rerio)


name: tetX HC transports tetX LC from target cell endosome membrane into cytosol (Homo sapiens)


name: 2-oxoglutarate + an N(1)-methyl-2'-deoxyadenosine in single-stranded DNA + O2 = a 2'-deoxyadenosine in single-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: chloride(out) + L-alanine(out) + 2 Na(+)(out) => chloride(in) + L-alanine(in) + 2 Na(+)(in)


name: (2E,6E)-farnesyl diphosphate <=> bicyclogermacrene + diphosphate


name: Release of platelet cytosolic components (Caenorhabditis elegans)


name: 2-heptyl-4(1H)-quinolone + H(+) + NADH + O2 <=> 2-heptyl-3-hydroxy-4(1H)-quinolone + H2O + NAD(+)


name: RAC1:GTP binds NOX1 complex (Rattus norvegicus)


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Sus scrofa)


name: DHI and DHICA polymerize forming eumelanin (Sus scrofa)


name: 10-hydroperoxy-(8E)-octadecenoate => (9Z)-octadecenoate + O2


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)


name: p-Y701-STAT1 dimer translocates from the cytosol to the nucleus (Bos taurus)


name: 2'-deoxymugineate + NADP(+) => 3''-deamino-3''-oxonicotianamine + H(+) + NADPH


name: L-homocysteine + L-serine <=> H2O + L,L-cystathionine


name: 1-hexadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA => 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: (2E,13Z)-eicosadienoyl-CoA + H(+) + NADPH = (13Z)-eicosenoyl-CoA + NADP(+)


name: Pink1 is cleaved on healthy mitochondria (Drosophila melanogaster)


name: PIAS2-2 SUMOylates THRA with SUMO3 (Homo sapiens)


name: all-trans-5,6-epoxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-retinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Exocytosis of tertiary granule membrane proteins (Rattus norvegicus)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole => hapalindole H


name: Phosphorylation of JAK2 (Canis familiaris)


name: DMGDH:FAD oxidatively demethylates DMGLY to SARC (Homo sapiens)


name: 2 O2 + 2 reduced [NADPH--hemoprotein reductase] + silphinene-15-oate <=> gamma-lactone-2-keto[5.5.5.5]fenestrane + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: ethanolamine + H2O + O2 => glycolaldehyde + H2O2 + NH4(+)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Bos taurus)


name: beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + H2O => D-glucose + N-octadecanoylsphing-4-enine


name: taurine transmembrane transporter activity


name: (20S)-ginsenoside C-K + UDP-alpha-D-glucose => (20S)-ginsenoside F2 + H(+) + UDP


name: cholate(out) + n H(+)(out) => cholate(in) + n H(+)(in)


name: 3'-L-prolyl-AMP + holo-[peptidyl-carrier protein] => AMP + L-prolyl-[peptidyl-carrier protein]


name: L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => 2 H(+) + H2O + N-hydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: 7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) + CO2 + S-adenosyl-L-methionine <=> 2 H(+) + S-adenosyl-L-homocysteine + wybutosine(37) in tRNA(Phe)


name: A + ethylbenzene + H2O => (S)-1-phenylethanol + AH2


name: PTK2B is phosphorylated (Rattus norvegicus)


name: NEXT3 is cleaved to produce NICD3 (Xenopus tropicalis)


name: tartrate transmembrane transporter activity


name: NADPH + 2 oxidized [cytochrome P450] = H(+) + NADP(+) + 2 reduced [cytochrome P450]


name: 2-oxoglutarate + L-aspartyl-[protein] + O2 = (3S)-3-hydroxy-L-aspartyl-[protein] + CO2 + succinate


name: Binding of SHC1 to insulin receptor (Rattus norvegicus)


name: Rsu-1 interacts with Pinch1 (Rattus norvegicus)


name: (5S)-hydroxy-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase] => (5S,18)-dihydroxy-(6E,8Z)-octadecadienoate + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: Recruitment of clathrin coated vesicle by Ii (Rattus norvegicus)


name: H2O + L-tyrosine + O2 => 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: Formation Of Bloc-1 Complex (Homo sapiens)


name: an acyl-CoA + sn-glycero-3-phosphoethanolamine => a 2-acyl-sn-glycero-3-phosphoethanolamine + CoA


name: RAP1A exchanges GDP for GTP (Bos taurus)


name: p-Y393-ABL1 phosphorylates tyrosine-407 of YAP1 (Homo sapiens)


name: activating MHC class I receptor activity


name: α2-agonists bind ADRA2A,B,C (Xenopus tropicalis)


name: WNT ligands traffic to the plasma membrane (Gallus gallus)


name: nor-toralactone + S-adenosyl-L-methionine => H(+) + S-adenosyl-L-homocysteine + toralactone


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Plasmodium falciparum)


name: Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Canis familiaris)


name: PTK2 is recruited to methylated ESR1 (Canis familiaris)


name: G13 activation by TP receptor (Danio rerio)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => diphosphate + somaliensene A


name: ERCC8 (CSA) binds stalled RNA Pol II (Canis familiaris)


name: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 <=> CO2 + H(+) + H2O + scopolamine + succinate


name: RHOA GEFs activate RHOA (Xenopus tropicalis)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Caenorhabditis elegans)


name: Caspase 3-mediated cleavage of DFF45 (117) (Mus musculus)


name: cholest-4-en-3-one + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] => (25R)-3-oxocholest-4-en-26-oate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: allodeoxycholoyl-CoA + beta-muricholate <=> allodeoxycholate + beta-muricholoyl-CoA


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Saccharomyces cerevisiae)


name: MARC1,MARC2 reduce N-hydroxylated compounds (Danio rerio)


name: MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Canis familiaris)


name: (R)-trihomocitrate + CoA + H(+) => 2-oxoheptanedioate + acetyl-CoA + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => (8S,9R)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Xenopus tropicalis)


name: a long-chain fatty aldehyde + H(+) + 2 NADPH + O2 => a long-chain alkane + formate + H2O + 2 NADP(+)


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Mus musculus)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Danio rerio)


name: GGT dimers hydrolyse APAP-SG (Rattus norvegicus)


name: Phosphorylation of CD28 (Rattus norvegicus)


name: L-threonate + NAD(+) <=> 3-dehydro-D-erythronate + H(+) + NADH


name: 2xPDXK:2xZn2+ phosphorylates PXA (Saccharomyces cerevisiae)


name: ATP + glycyl-L-asparagine(out) + H2O => ADP + glycyl-L-asparagine(in) + H(+) + phosphate


name: BIL translocates to the nucleus (Homo sapiens)


name: pro-RAS proteins are farnesylated (Bos taurus)


name: HDAC8 deacetylates histones (Canis familiaris)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)


name: NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Canis familiaris)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) (Canis familiaris)


name: L-canavanine + L-ornithine <=> H(+) + L-arginine + L-canaline


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Xenopus tropicalis)


name: ACSF3 ligates CoA-SH to VLCFA (Homo sapiens)


name: HDACs deacetylate p-STAT3 dimers (Sus scrofa)


name: Recruitment of SHC1 is mediated by Y593 of the common beta chain (Homo sapiens)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Dictyostelium discoideum)


name: 15-cis-4,4'-diapophytoene + 3 FAD + 3 H(+) <=> all-trans-4,4'-diaponeurosporene + 3 FADH2


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + a 1,2-diacyl-sn-glycerol => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli)


name: alpha-D-glucose 1-phosphate + D-glucose => beta-D-glucosyl-(1->3)-D-glucose + phosphate


name: 4-methoxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP => 4-methoxyestrone + UDP-alpha-D-glucuronate


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(36)-[histone H3] + 2 succinate


name: POLZ extends translesion synthesis (Canis familiaris)


name: H2O + juglone => naphthalene-1,2,4,8-tetrol


name: 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)


name: ergosterol + NADP(+) <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+) + NADPH


name: Interaction of integrin alphaVbeta3 with Fibrillin (Bos taurus)


name: SREBP1A,1C,2 binds Importin beta-1 (Caenorhabditis elegans)


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Mus musculus)


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: (9Z)-octadecenoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: Assembly of the pre-incision complex in TC-NER (Rattus norvegicus)


name: a jasmonyl-L-amino acid + O2 + reduced [NADPH--hemoprotein reductase] = a 12-hydroxyjasmonyl-L-alpha-amino acid + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + NADP(+) + phosphate = [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + H(+) + NADPH


name: "[amino-group carrier protein]-5-phospho-L-glutamate reductase"


name: 1,2-diacyl-glycero-3-phosphocholine + an N-acylsphing-4-enine => a 1,2-diacylglycerol + a sphingomyelin


name: HSD17B3-like proteins reducde ANDST to TEST (Plasmodium falciparum)


name: coproporphyrinogen III + 3 O2 <=> coproporphyrin III + 3 H2O2


name: allantoate + H(+) => (S)-allantoin + H2O


name: H2O + N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] <=> (S)-4,5-dihydroxy-2-oxopentanal + L-lysyl-[protein] + phosphate


name: 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Mus musculus)


name: (9Z)-octadecenoyl-CoA + cholesterol => cholesteryl (9Z-octadecenoate) + CoA


name: Beclin-1 complex phosphorylates PtdIns (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + a monoacyl-sn-glycero-3-phosphocholine + H(+)


name: Internalization of receptor bound antigen into clathrin coted vesicles (Danio rerio)


name: GPIb-IX-V binds to vWF:Collagen complex (Xenopus tropicalis)


name: CO2 + H2O + violacein => H(+) + O2 + violaceinate


name: H2O + N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine <=> D-glucose + N-acyl-15-methylhexadecasphing-4-enine


name: N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine <=> (9Z,12Z,15Z)-octadecatrienamide + glyoxylate


name: (9Z)-octadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: Removal of fibrillar collagen C-propeptides (Canis familiaris)


name: carbamoyl phosphate + L-lysine = H(+) + L-homocitrulline + phosphate


name: CYP1A2 hydroxylates AFB1 to AFM1 (Homo sapiens)


name: glycine + H(+) + succinyl-CoA => 5-aminolevulinate + CO2 + CoA


name: cadaverine + H2O + O2 => 5-aminopentanal + H2O2 + NH4(+)


name: 3-O-(alpha-L-fucosyl)-L-threonyl-[protein] + UDP-alpha-D-glucose => 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[protein] + H(+) + UDP


name: carboxyspermidine + H(+) = CO2 + spermidine


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Canis familiaris)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Gallus gallus)


name: KRAS4B is phosphorylated on serine 181 (Caenorhabditis elegans)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:phospho-IRS2 binds PI3K (Sus scrofa)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Homo sapiens)


name: 8-demethyl-8-(methylamino)riboflavin + S-adenosyl-L-methionine <=> H(+) + roseoflavin + S-adenosyl-L-homocysteine


name: IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Canis familiaris)


name: dodecanoate + H(+) + H2O2 => dodecanal + H2O + O2


name: ACSF3 ligates CoA-SH to VLCFA (Mus musculus)


name: (9Z)-octadecenoyl-CoA + sn-glycerol 3-phosphate <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA


name: Phosphorylation of APC component of the destruction complex (Rattus norvegicus)


name: 7 CO2 + 8 CoA + 6 H2O + 11 NADP(+) + wortmanamide A => 5-aminopentanoate + acetyl-CoA + 17 H(+) + 7 malonyl-CoA + 11 NADPH


name: uridine(54/55) in tRNA = pseudouridine(54/55) in tRNA


name: 2-deoxy-scyllo-inosamine + NAD(+) <=> 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADH


name: calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration


name: ANO1 transports cytosolic Cl- to extracellular region (Gallus gallus)


name: acyl-lipid omega-3 desaturase (cytochrome b5) activity


name: (+)-aristolochene + diphosphate => (2E,6E)-farnesyl diphosphate


name: H(+) + hydroxyacetone + NADH <=> (S)-propane-1,2-diol + NAD(+)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Dictyostelium discoideum)


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Gallus gallus)


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Bos taurus)


name: cobalt ion transmembrane transporter activity


name: a (2R)-2-hydroxycarboxylate + NADP(+) => a 2-oxocarboxylate + H(+) + NADPH


name: CDK6 inhibitors bind CDK6 (Gallus gallus)


name: MBTPS1 (S1P) cleaves CREB3L3 (Xenopus tropicalis)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Saccharomyces cerevisiae)


name: an L-alpha-amino acid + ATP + L-arginine = ADP + H(+) + L-arginyl-L-alpha-amino acid + phosphate


name: "L-arginine-specific L-amino acid ligase"


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + n acetyl-CoA <=> [O(7),N-diacetyl-alpha-D-neuraminosyl-(2->8)](n) + n CoA


name: C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Homo sapiens)


name: H(+) + holo-[ACP] + tetradecanoate => H2O + tetradecanoyl-[ACP]


name: 2 Fe(III)-[cytochrome c] + 2 thiosulfate = 2 Fe(II)-[cytochrome c] + 2 H(+) + tetrathionate


name: Phosphorylation of PLCgamma by PDGFR (Rattus norvegicus)


name: (indol-3-yl)acetate + ATP + CoA => (indol-3-yl)acetyl-CoA + AMP + diphosphate


name: C-ter TLR7 dimer binds HCQ (Canis familiaris)


name: Integrin alpha5beta1 binds FN1 dimer (Homo sapiens)


name: CYP4F8 19-hydroxylates PGH2 (Canis familiaris)


name: (3S)-citryl-CoA + acetate => acetyl-CoA + citrate


name: MATEs mediate extrusion of xenobiotics (Homo sapiens)


name: SESN1,2 binds L-leucine and dissociates from GATOR2 (Mus musculus)


name: 2-oxoglutarate + L-proline + O2 => cis-3-hydroxy-L-proline + CO2 + succinate


name: PAQR3 binds inactive RAFs (Homo sapiens)


name: AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)


name: TRPA1 tetramer binds TRPA1 antagonists (Danio rerio)


name: (1S,2S,4R)-limonene-1,2-diol + NAD(+) => (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADH


name: (1R,2R,3R)-prephytoene diphosphate + H(+) + NADPH => all-trans-lycopaoctaene + diphosphate + NADP(+)


name: glycine + hexacosanoyl-CoA => CoA + H(+) + N-hexacosanoylglycine


name: trans-Golgi Network Lysosomal Vesicle Scission (Gallus gallus)


name: RAC1 binds effectors at the plasma membrane (Dictyostelium discoideum)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Sus scrofa)


name: L-cysteine + O-acetyl-L-homoserine <=> acetate + H(+) + L,L-cystathionine


name: D-glucose(out) + H(+)(in) => D-glucose(in) + H(+)(out)


name: Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Rattus norvegicus)


name: (2E,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + H(+) + NADPH <=> (11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + NADP(+)


name: H2O + pyrrole-2-carboxylate <=> 1H-pyrrole + hydrogencarbonate


name: Formation of Pol zeta complex (Canis familiaris)


name: RUNX1 binds the SOCS4 gene (Homo sapiens)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Mus musculus)


name: ATP + H2O + sitosterol(in) <=> ADP + H(+) + phosphate + sitosterol(out)


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Sus scrofa)


name: histidine => urocanate + NH4+ (Mus musculus)


name: H(+) + hydroxylamine + L-asparagine = beta-L-aspartylhydroxamate + NH4(+)


name: 3 Fe(III)-[cytochrome c] + hydroxylamine = 3 Fe(II)-[cytochrome c] + 3 H(+) + nitric oxide


name: (Z)-N-(sulfonatooxy)prop-2-enimidothioate <=> allyl thiocyanate + sulfate


name: a 2-acyl-sn-glycero-3-phosphocholine + a lipid IIB => a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid IIA


name: DHCA is translocated from the mitochondrial matrix to the cytosol (Homo sapiens)


name: Arachidonate is epoxidated to 8,9-EET by CYP(5) (Drosophila melanogaster)


name: (S)-2-hydroxyglutarate(in) + 3 Na(+)(in) => (S)-2-hydroxyglutarate(out) + 3 Na(+)(out)


name: butanoyl-CoA + phosphate <=> butanoyl phosphate + CoA


name: ADP(in) + CoA(out) => ADP(out) + CoA(in)


name: POLI incorporates dNMP opposite to damaged DNA base (Homo sapiens)


name: ATP + H2O + thiosulfate(out) = ADP + H(+) + phosphate + thiosulfate(in)


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Rattus norvegicus)


name: SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Rattus norvegicus)


name: CHIT1 hydrolyses CHIT to 3xADGP (Drosophila melanogaster)


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: an all-trans-retinyl ester + H2O => a fatty acid + all-trans-retinol + H(+)


name: (E)-4-coumaroyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = an anthocyanidin 3-O-[6-O-(4-hydroxycinnamoyl)-beta-D-glucoside] + CoA + H(+)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Sus scrofa)


name: acetyl-CoA + benzyl alcohol => benzyl acetate + CoA


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Homo sapiens)


name: C3a receptor binds anaphylatoxin C3a (Canis familiaris)


name: 3beta-hydroxyandrost-5-en-17-one + H(+) + NADH => androst-5-en-3beta,17beta-diol + NAD(+)


name: 1,5-anhydro-D-fructose <=> ascopyrone M + H2O


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Drosophila melanogaster)


name: LTC4 is exported from the cytosol by ABCC1 (Dictyostelium discoideum)


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Sus scrofa)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Xenopus tropicalis)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)


name: SUMOylation of PCNA with SUMO1 (Bos taurus)


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Mus musculus)


name: Binding of A1CF to stem-looped RNA (Sus scrofa)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in) <=> 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: a 3-oxoacyl-[ACP] + acetyl-[ACP] + H2O <=> a 3-carboxymethyl-3-hydroxy-acyl-[ACP] + H(+) + holo-[ACP]


name: CO2 + H2O + NADP(+) + naphthalene-1,2-diol => 1-hydroxy-2-naphthoate + 2 H(+) + NADPH + O2


name: dimethylallyl diphosphate + L-tryptophan => 4-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: 1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexanoate


name: alpha-isomaltosyl-(1->3)-isomaltose + H2O => 2 isomaltose


name: quercetin + UDP-beta-L-rhamnose => H(+) + quercitrin + UDP


name: PLOD3:Fe2+ dimer:Galactosyl-hydroxylysyl collagen propeptides dissociates (Caenorhabditis elegans)


name: p-6Y-SYK phosphorylates BLNK (SLP65) (Canis familiaris)


name: Nitrogen dioxide is reduced to NO by F420 (Homo sapiens)


name: (2S)-2-hydroxydecanenitrile => hydrogen cyanide + nonanal


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Xenopus tropicalis)


name: SREBP1A,2 binds the CYP51A1 promoter (Homo sapiens)


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Bos taurus)


name: (S)-malate(in) + phosphate(out) <=> (S)-malate(out) + phosphate(in)


name: Interaction of DAP12 and KIR2DS4 (Homo sapiens)


name: LDLR:LDL complex => LDLR + LDL (Rattus norvegicus)


name: Separation of elongating transcript from template (Xenopus tropicalis)


name: benzoate + H(+) + NADH + O2 = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: SLC36A1-mediated uptake of glycine, proline, and alanine (Mus musculus)


name: BTK in PIP3:BTK:G beta-gamma complex is activated (Drosophila melanogaster)


name: MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)


name: phloretin + UDP-alpha-D-glucose => H(+) + trilobatin + UDP


name: F8 variant is not secreted (Homo sapiens)


name: ULK1 phosphorylates Beclin-1 (Rattus norvegicus)


name: 1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity


name: TP53BP1 recruits DCLRE1C to ATM (Gallus gallus)


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Canis familiaris)


name: D-tryptophan + O2 = N-formyl-D-kynurenine


name: Part of pro-beta-NGF is processed to mature beta-NGF (Homo sapiens)


name: T1R1/T1R3 dimer is the umami taste receptor (Mus musculus)


name: CANX dissociates from IL12A:EBI3 (Rattus norvegicus)


name: VTN binds collagens II, III and V (Xenopus tropicalis)


name: Clathrin internalises EPH:EFN complexes (Caenorhabditis elegans)


name: CDC42 binds effectors at the plasma membrane (Canis familiaris)


name: Formation of anchoring fibrils (Homo sapiens)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Sus scrofa)


name: L-idonate 5-dehydrogenase (NAD+) activity


name: RNF146 polyubiquitinates PARylated PTEN (Rattus norvegicus)


name: 2 Fe(II)-[cytochrome c] + 3 H(+) + ouabagenin = dihydroouabagenin + 2 Fe(III)-[cytochrome c]


name: H2O2 + tetradecanal => O2 + tetradecan-1-ol


name: 2-oxoglutarate + GDP-D-glycero-alpha-D-manno-heptose => (S)-2-hydroxyglutarate + GDP-D-glycero-4-keto-alpha-D-lyxo-heptose


name: Slo3 Potassium Transport (Canis familiaris)


name: 3-methyl-2-oxobutanoate + H(+) + NADPH => (R)-2-hydroxy-3-methylbutyrate + NADP(+)


name: 2 Fe(III)-[cytochrome c3] + H2 <=> 2 Fe(II)-[cytochrome c3] + 2 H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> diphosphate + talarodiene


name: acetyl-CoA + N-terminal L-methionyl-L-alanyl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-alanyl-[protein]


name: 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP => (indol-3-yl)acetate + UDP-alpha-D-glucose


name: 2xTNFR2 binds TNFA trimer:TNFR2 (Mus musculus)


name: p-STAT1:p-STAT4 translocates to the nucleus (Drosophila melanogaster)


name: PGM1:Mg2+ isomerises G6P to G1P (Dictyostelium discoideum)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Bos taurus)


name: Activated type I receptor phosphorylates SMAD2/3 directly (Caenorhabditis elegans)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Bos taurus)


name: ISGylation of host proteins (Caenorhabditis elegans)


name: (R)-2-hydroxy-4-methylpentanoate + NADP(+) <=> 4-methyl-2-oxopentanoate + H(+) + NADPH


name: Autophosphorylation of PDGF beta receptors (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H(+) + N-retinylidene-N-retinylethanolamine <=> H2O + N-retinylidene-N-retinylphosphatidylethanolamine


name: NTPDase4 hydrolyzes nucleoside diphosphates (Homo sapiens)


name: PLK2 phosphorylates NPM1 (Canis familiaris)


name: 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + 2 H2O + NADP(+) => 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + H(+) + NADPH + O2


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Gallus gallus)


name: USP14 deubiquitinates NLRC5 (Sus scrofa)


name: USP18 binds IKBKG within IKK complex (Rattus norvegicus)


name: (20S)-ginsenoside C-K + UDP-alpha-D-glucose = (20S)-ginsenoside F2 + H(+) + UDP


name: Activated FGFR4 phosphorylates FRS2 (Caenorhabditis elegans)


name: Oxidative demethylation of 3-meC damaged DNA by ALKBH2 (Homo sapiens)


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 = 1-O-methyl-(9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: 1D-myo-inositol 1-phosphate + an N-acyl-(4R)-4-hydroxysphinganine + H(+) => an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + H2O


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA <=> 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA


name: Defective GALNT3 does not transfer GalNAc to mucins (Homo sapiens)


name: CALM1:Ca2+ binds CNG channel (Mus musculus)


name: SMAD2,3 and GATA6-AS1 lncRNA bind the GATA6 gene (Homo sapiens)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Gallus gallus)


name: EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: TFR2 dimer binds 2xholoTF (Rattus norvegicus)


name: (2E)-dodecenoate + CoA + H(+) => (2E)-dodecenoyl-CoA + H2O


name: Co-precorrin-6A + H(+) + NADH => Co-precorrin-6B + NAD(+)


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Mus musculus)


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Homo sapiens)


name: Co-repressor complex dissociates from the transcription unit of the UGT1A3 gene  (Homo sapiens)


name: H2O + nitrite + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + nitrate + 2 reduced [2Fe-2S]-[ferredoxin]


name: RUNX1 and ESR1 bind the GPAM gene enhancer (Homo sapiens)


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Bos taurus)


name: BDNF gene expression is stimulated by NPAS4:ARNT2 (Homo sapiens)


name: ADP + beta-D-fructose 1-phosphate + H(+) => ATP + beta-D-fructose


name: (3S)-citramalyl-CoA => 3-methylfumaryl-CoA + H2O


name: deoxycholoyl-CoA + NAD(+) => 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + H(+) + NADH


name: DAAM1 recruits GTP-bound RHOA (Rattus norvegicus)


name: 4-methylumbelliferone beta-D-glucuronate + H2O => 4-methylumbelliferone + D-glucuronate


name: a triacyl-sn-glycerol + CoA => a 1,3-diacyl-sn-glycerol + an acyl-CoA


name: 9,9',15-tri-cis-zeta-carotene + 2 a plastoquinol => 15-cis-phytoene + 2 a plastoquinone


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)


name: Formation of FACT complex (Canis familiaris)


name: a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O <=> a 1-O-alkyl-2-acetyl-sn-glycerol + H(+) + phosphocholine


name: loading of Serotonin in synaptic vesicles (Bos taurus)


name: PTP-RO interacts with p-c-Kit complex (Sus scrofa)


name: VRI replaces PDP1 as binder to Clk and cry genes (Drosophila melanogaster)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phospho-(1'-myo-inositol-5'-phosphate) + H2O => 1-O-alkyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + phosphate


name: 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate + 8 AH2 => 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 A


name: D-serine(out) + H(+)(out) => D-serine(in) + H(+)(in)


name: 3-hydroxy-2-methylpyridine-5-carboxylate + NADPH + O2 <=> 2-(acetamidomethylene)succinate + NADP(+)


name: GLB1 hydrolyses a glycosaminoglycan (Dictyostelium discoideum)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: cyclo(L-tyrosyl-L-tyrosyl) + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + mycoclysin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: deacetylation of O-acetylserine and sulfhydrylation using CysK2 (Mycobacterium tuberculosis)


name: TWIST1 binds the RUNX2 gene promoter (Homo sapiens)


name: DHFR2 reduces FOLA to DHF (Canis familiaris)


name: 22-hydroxydocosanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 22-oxodocosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP


name: PP2A dephosphorylates serine-127 of YAP1 (Bos taurus)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Danio rerio)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Rattus norvegicus)


name: SLC22A12 exchanges extracellular urate for cytosolic LACT (Homo sapiens)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(out) => a 1,2-diacyl-sn-glycero-3-phosphocholine(in)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + serotonin => CoA + H(+) + N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin


name: ergosterol + NADP(+) = ergosta-5,7,22,24(28)-tetraen-3beta-ol + H(+) + NADPH


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)


name: STARD5 binds DCA, LCA (Xenopus tropicalis)


name: cortisone + O2 + reduced [NADPH--hemoprotein reductase] <=> 6beta-hydroxycortisone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a dipeptide(out) + ATP + H2O <=> a dipeptide(in) + ADP + H(+) + phosphate


name: (7S)-O-acetylsalutaridinol = acetate + H(+) + thebaine


name: IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Canis familiaris)


name: ent-3beta-hydroxycassa-12,15-dien-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => ent-cassa-12,15-dien-2beta,3beta-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: 1-hexadecanoyl-sn-glycero-3-phosphate + NADP(+) <=> 1-hexadecanoylglycerone 3-phosphate + H(+) + NADPH


name: Unwinding of DNA for the Nascent Transcript: Second Transition (Schizosaccharomyces pombe)


name: 2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]acetate + H(+) + H2O = 2-dehydro-D-glucose + glycine


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphate <=> a 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA


name: beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose => alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP + H(+)


name: CBL binds and ubiquitinates phosphorylated Sprouty (Canis familiaris)


name: PDP1,2 dephosphorylate p-lipo-PDH (Sus scrofa)


name: Translocation of NFATC1:CaN:CaM to nucleus (Dictyostelium discoideum)


name: CGRP receptor can bind calcitonin gene-related peptides (Mus musculus)


name: CANX dissociates from IL12A:EBI3 (Homo sapiens)


name: Degradation of multiubiquitinated Securin (Mus musculus)


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Gallus gallus)


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)


name: 3',3'-cUAMP + 2 diphosphate => ATP + UTP


name: MITF-M dimer binds the CCND1 gene (Homo sapiens)


name: 2 ADP + 2 H(+) + hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 phosphate => 2 ATP + 2 H2O + hydrogenobyrinate + 2 L-glutamine


name: histone H3R8 arginine deiminase activity


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Canis familiaris)


name: 27-hydroxysterol binds ESR1, ESR2 (Danio rerio)


name: Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Canis familiaris)


name: MAOA:FAD deaminates DA to DOPAC (Sus scrofa)


name: Expression of APOC4 regulated by NR1H2 or NR1H3 (Homo sapiens)


name: botE HC transports botE LC from target cell synaptic vesicle membrane into cytosol (Homo sapiens)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Caenorhabditis elegans)


name: 5-phospho-alpha-D-ribose 1-diphosphate + orotate => diphosphate + orotidine 5'-phosphate


name: (2E)-geranyl diphosphate => (1R,5R)-alpha-pinene + diphosphate


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Mus musculus)


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl beta-D-glucuronate(out) + ADP + H(+) + phosphate => 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl beta-D-glucuronate(in) + ATP + H2O


name: Interleukin-1 receptor type 2 binds Interleukin 1 (Mus musculus)


name: Active ALK phosphorylates FRS2 (Homo sapiens)


name: GSTZ1 isomerizes 4-MAA (Rattus norvegicus)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Rattus norvegicus)


name: Aquaporin-1 passively transports water out of cell (Bos taurus)


name: (S)-1-pyrroline-5-carboxylate + 2 H2O + NAD(+) <=> H(+) + L-glutamate + NADH


name: H(+) + N(2)-methylguanosine(6) in tRNA + S-adenosyl-L-homocysteine => guanosine(6) in tRNA + S-adenosyl-L-methionine


name: (2E,6E,10E)-geranylgeraniol + GTP => (2E,6E,10E)-geranylgeranyl phosphate + GDP + H(+)


name: (R)-1-aminopropan-2-yl phosphate + adenosylcob(III)yrate + ATP <=> adenosylcob(III)inamide phosphate + ADP + H(+) + phosphate


name: PIAS2-2 SUMOylates THRA with SUMO1 (Sus scrofa)


name: 3-oxopropanoate + CoA + NADP(+) = H(+) + malonyl-CoA + NADPH


name: "malonyl CoA reductase (malonate semialdehyde-forming)"


name: 2'-deoxymugineate + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineate + CO2 + H(+) + succinate


name: "[methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase"


name: RHOG GEFs activate RHOG (Caenorhabditis elegans)


name: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)


name: 4-methyl,4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form 4-methylcholesta-8(9),24-dien-3-one (Sus scrofa)


name: 3-oxodecanoyl-[ACP] + CO2 + CoA => H(+) + malonyl-[ACP] + octanoyl-CoA


name: 2-deoxy-D-glucose + ATP = 2-deoxy-D-glucose 6-phosphate + ADP + H(+)


name: Change of PKC theta conformation (Canis familiaris)


name: Dephosphorylation of Gab1 by SHP2 (Canis familiaris)


name: Monoiodinated tyrosine can be deiodinated (Sus scrofa)


name: HIF-alpha translocates from cytosol to nucleus (Bos taurus)


name: 6-deoxyerythronolide B + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => erythronolide B + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + L-serine <=> a 1,2-diacyl-sn-glycero-3-phospho-L-serine + ethanolamine


name: ethylnitronate + FMNH2 + O2 = acetaldehyde + FMN + 2 H(+) + H2O + nitrite


name: APAF1:CYCS binds APIP (Rattus norvegicus)


name: Spermidine  => N-acetylated spermidine (Sus scrofa)


name: H(+) + N(6),N(6)-dimethyl-L-lysine <=> CO2 + N,N-dimethyl-cadaverine


name: 10-hydroxy-alpha-humulene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => alpha-humulene + O2 + reduced [NADPH--hemoprotein reductase]


name: FGFR2b mutants bind an expanded range of ligands (Homo sapiens)


name: mercaptopurine + S-adenosyl-L-methionine => 6-methylthiopurine + H(+) + S-adenosyl-L-homocysteine


name: 2 H(+) + narbomycin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pikromycin


name: adenosine 3',5'-bisphosphate(out) + FMN(in) = adenosine 3',5'-bisphosphate(in) + FMN(out)


name: (S)-2,3-epoxysqualene + 2 Fe(III)-[cytochrome b5] + H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + squalene


name: (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2


name: ACO2 isomerizes citrate (Saccharomyces cerevisiae)


name: (4Z,15Z)-bilirubin IXalpha + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> biliverdin IXalpha + reduced coenzyme F420-(gamma-L-Glu)(n)


name: Interaction of integrin alphaVbeta3 with Fibrillin (Gallus gallus)


name: Synthesis of full-length duplex viral DNA with a discontinuous plus strand (Homo sapiens)


name: Chondroitin can be sulfated on position 4 of GalNAc by CHST9, 11, 12 and 13 (Drosophila melanogaster)


name: a 2'-O-methyluridine in 21S rRNA + H(+) + S-adenosyl-L-homocysteine => a uridine in 21S rRNA + S-adenosyl-L-methionine


name: hydrogen cyanide + pentan-2-one = (2S)-2-hydroxy-2-methylpentanenitrile


name: D-beta hydroxybutyrate+NAD+ <=> acetoacetate+NADH+H+ (Homo sapiens)


name: (4,5-dibromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O => (5-bromo-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + bromide + FADH2 + O2


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Rattus norvegicus)


name: a ganglioside GD1alpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1aalpha (d18:1(4E)) + CMP + H(+)


name: beta-D-fructose 1,6-bisphosphate + H2O <=> beta-D-fructose 6-phosphate + phosphate


name: Abortive initiation after formation of the first phosphodiester bond (Saccharomyces cerevisiae)


name: 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol => 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: MPHOSPH8 (MPP8) in HUSH complex binds histone H3 trimethyl-lysine 9 (H3K9me3) in L1HS,L1PA2,3 heterochromatin (Homo sapiens)


name: Dissociation of Phospho-Nlp from the centrosome (Bos taurus)


name: formate(out) + 2 H(+)(in) + ubiquinone-8 <=> CO2(out) + H(+)(out) + ubiquinol-8


name: DOCKs bind to RhoGEFs (Caenorhabditis elegans)


name: KCTD1 binds TFAP2 homo- and heterodimers (Sus scrofa)


name: 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA => (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine


name: 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate => 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-O-hexadecyl-sn-glycero-3-phosphocholine <=> 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Xenopus tropicalis)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Gallus gallus)


name: ELOVL1,2,3,5 elongate AA-CoA and Mal-CoA to 3ODCT-CoA (Bos taurus)


name: 5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity


name: 5S-HETE is oxidised to 5-oxoETE by 5-HEDH (Homo sapiens)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Canis familiaris)


name: Caspase-8 cleaves IL1B precursor (Bos taurus)


name: chloride + L-tyrosine + NADP(+) <=> 3-chloro-L-tyrosine + NADPH


name: (11E)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (6Z,11E)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2-oxohexanoate + L-kynurenine => 4-(2-aminophenyl)-2,4-dioxobutanoate + L-2-aminohexanoate


name: pro-F2R binds vorapaxar (Rattus norvegicus)


name: 3',5'-cyclic GMP(out) + a dicarboxylate(in) = 3',5'-cyclic GMP(in) + a dicarboxylate(out)


name: glycyl-tRNA(Ala) + H2O => glycine + H(+) + tRNA(Ala)


name: COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + 1-O-hexadecyl-sn-glycero-3-phosphocholine => 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Bos taurus)


name: propanoyl-CoA + tetradecanoyl-CoA = 3-oxo-2-methylhexadecanoyl-CoA + CoA


name: UDP-N-acetylgalactosamine transmembrane transporter activity


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Caenorhabditis elegans)


name: H(+) + S-adenosyl-L-homocysteine + small RNA 3'-end 2'-O-methylnucleotide => S-adenosyl-L-methionine + small RNA 3'-end nucleotide


name: (tRNA)-3'-end (ribonucleoside 5'-phosphate)-(guanosyl 5'-phosphate)-(cytosyl 5'-phosphate)-(cytosyl 5'-phosphate)-(adenosine 5'-phosphate) + H2O <=> GpCpCpA + H(+) + tRNA 3'-end (ribonucleotide 3'-phosphate)


name: Coumarin is 7-hydroxylated by CYP2A6 (Canis familiaris)


name: 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine => 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: LKB1 forms a trimeric complex with STRAD and MO25 (Bos taurus)


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Mus musculus)


name: Carbonic anhydrase dehydrates bicarbonate (plasma membrane) (Caenorhabditis elegans)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Rattus norvegicus)


name: EOMES, SMAD2,3, and GATA6 bind the CXCR4 gene (Homo sapiens)


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Sus scrofa)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-GDP


name: glycine + octanoyl-CoA = CoA + H(+) + N-octanoylglycine


name: Dehydrogenation of 3-hydroxy tetracosahexaenoyl-CoA (Drosophila melanogaster)


name: D-glutamine + H2O = D-glutamate + NH4(+)


name: CBL ubiquitinates FRS2 and FGFR2 (Canis familiaris)


name: dihydrochanoclavine-I aldehyde + NADP(+) <=> chanoclavine-I aldehyde + H(+) + NADPH


name: a jasmonate + an L-alpha-amino acid + ATP = a jasmonyl-L-amino acid + AMP + diphosphate + H(+)


name: TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Homo sapiens)


name: ornithine => putrescine + CO2 (Plasmodium falciparum)


name: ATP(in) + CoA(in) + H(+)(out) + octadecanoate(out) <=> AMP(in) + diphosphate(in) + H(+)(in) + octadecanoyl-CoA(in)


name: AMP + diphosphate + tetradecanoyl-[ACP] => ATP + holo-[ACP] + tetradecanoate


name: PROT mediates L-proline uptake (Gallus gallus)


name: TLR4-induced ripoptosome assembly (Mus musculus)


name: 2 Fe(III)-[leghemoglobin] + NADH => 2 Fe(II)-[leghemoglobin] + H(+) + NAD(+)


name: Defective GALE does not epimerise UDP-Gal to UDP-Glc (Homo sapiens)


name: Retromer associates with WLS (Drosophila melanogaster)


name: OTUD3 deubiquitinates PTEN (Mus musculus)


name: CTDNEP1:CNEP1R1 dephosphorylates LPIN (Rattus norvegicus)


name: (E)-4-coumaroyl alcohol + NADP(+) <=> (E)-4-coumaraldehyde + H(+) + NADPH


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Dictyostelium discoideum)


name: TDO tetramer dioxygenates L-Trp to NFK (Rattus norvegicus)


name: an 11beta-hydroxysteroid + NADP(+) = an 11-oxosteroid + H(+) + NADPH


name: geranylgeranyl diphosphate + H2O <=> (13E)-labda-7,13-dien-15-ol + diphosphate


name: SUMOylation of HDAC2 with SUMO1 (Sus scrofa)


name: "bacteriophage T4 restriction endoribonuclease RegB"


name: DLD dimer dehydrogenates dihydrolipoyl (Mus musculus)


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Bos taurus)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + tetradecanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-tetradecanoyl-sn-glycerol + CoA


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2 => (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate


name: (R)-carnitine + tetradecanoyl-CoA <=> CoA + O-tetradecanoyl-(R)-carnitine


name: acetyl-CoA + carnitine => acetylcarnitine + CoASH (Xenopus tropicalis)


name: XDH oxidizes xanthine to form urate (Sus scrofa)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Kinesins bind microtubules (Rattus norvegicus)


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 20S,25-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: alpha-D-galactose + ATP => ADP + alpha-D-galactose 1-phosphate + H(+)


name: 4-nitro-6-oxohepta-2,4-dienedioate = 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite


name: an N-acyleicosasphinganine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 2 Fe(III)-[cytochrome b5] + H2O + N-acyl-4-hydroxyeicosasphinganine


name: (4R)-limonene + H(+) + NADH + O2 <=> H2O + limonene 1,2-epoxide + NAD(+)


name: 4-(trimethylamino)butanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = crotonobetainyl-CoA + reduced [electron-transfer flavoprotein]


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl-(1->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O => (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: rebaudioside D + UDP-alpha-D-glucose = H(+) + rebaudioside M + UDP


name: Active ARF recruits coatomer (Saccharomyces cerevisiae)


name: ARHGAP35 stimulates RHOA GTPase activity (Drosophila melanogaster)


name: a 2'-deoxyribonucleoside 5'-diphosphate + GDP => a 2'-deoxyribonucleoside 5'-phosphate + GTP


name: adenosine 3',5'-bisphosphate + alpha-muricholate 7-sulfate + H(+) => 3'-phosphoadenylyl sulfate + alpha-muricholate


name: WWP2 ubiquitinates NOTCH3 (Gallus gallus)


name: HSF1 is activated by phosphorylation, translocation to the nucleus, and trimerization (Canis familiaris)


name: AH2 + cannabichromenate => A + cannabigerolate


name: Formation of Cyclin E:Cdk2 complexes (Rattus norvegicus)


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Mus musculus)


name: granulocyte macrophage colony-stimulating factor receptor binding


name: ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Danio rerio)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DHA to 13(S),14(S)-epoxy-DHA (Rattus norvegicus)


name: ERCC8 (CSA) binds stalled RNA Pol II (Sus scrofa)


name: [protein]-dithiol + NAD(+) = [protein]-disulfide + H(+) + NADH


name: a ganglioside GM2 + H2O = a ganglioside GA2 + N-acetylneuraminate


name: Plk1-mediated phosphorylation of Nlp (Bos taurus)


name: (9E)-octadecenoyl-CoA + H2O <=> (9E)-octadecenoate + CoA + H(+)


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Sus scrofa)


name: SESN1,2,3 bind overoxidized PRDX1 (Sus scrofa)


name: CMP + ganglioside GD1a (18:1(4E)/18:0) + H(+) => CMP-N-acetyl-beta-neuraminate + ganglioside GM1 (d18:1(4E)/18:0)


name: 6-chloro-D-tryptophan + FAD + 2 H2O => chloride + D-tryptophan + FADH2 + O2


name: 2,4-didehydro-3-deoxy-L-rhamnonate + H2O = (S)-lactate + H(+) + pyruvate


name: D-xylonate + H(+) => D-xylono-1,5-lactone + H2O


name: DPP4 binds DPP4 inhibitors (Gallus gallus)


name: Dimerized phospho-IRF3 migrates to the nucleus (Rattus norvegicus)


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Gallus gallus)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Saccharomyces cerevisiae)


name: 2-methoxy-6-all-trans-nonaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = 6-methoxy-3-methyl-2-all-trans-nonaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O => (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + H(+)


name: 3-acetamidopropanal + H2O2 + spermidine => H2O + N(1)-acetylspermine + O2


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Bos taurus)


name: Constitutive phosphorylation  by pERK1/2 (Rattus norvegicus)


name: acetaldehyde + H2O + NAD(+) => acetate + 2 H(+) + NADH


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Homo sapiens)


name: Proteasome mediated degradation of Cyclin D1 (Bos taurus)


name: PS is hydrolyzed to 1-acyl LPS by PLA2[15] (Mus musculus)


name: HSP70:DNAJB1 binds HSF1 (Canis familiaris)


name: ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Rattus norvegicus)


name: [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + H(+) + phosphate => [L-4-(L-arginin-2-N-yl)aspartate](n) + ATP + L-aspartate


name: "sn-1 acyl-lipid omega-3 desaturase (ferredoxin)"


name: LARG activation by G alpha 12/13 (Canis familiaris)


name: ADP + C-terminal S-cyanate-L-cysteinyl-[HypE protein] + H(+) + phosphate => ATP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein]


name: a (4E,8E)-4-sphinga-4,8-dienine ceramide + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 2 Fe(III)-[cytochrome b5] + 2 H2O + N-acyl-(4E,8E,10E)-sphingatrienine


name: 5a,11a-dehydrooxytetracycline + reduced coenzyme F420-(gamma-L-Glu)(n) => H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + oxytetracycline


name: SPP1 (osteopontin) binds integrin alpha8beta1 (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine => (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) <=> 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH


name: AFG3L2 degrades mitochondrial matrix proteins (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol = a 1,2-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: (+)-5-epi-aristolochene + O2 + reduced [NADPH--hemoprotein reductase] = 2beta-hydroxy-5-epi-aristolochene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)


name: 2-oxoglutarate + an alkane-alpha,omega-diamine <=> an omega-aminoaldehyde + L-glutamate


name: Elongation of Extended Telomeric Chromosome End (Mus musculus)


name: NAD(+) + phosphate => ADP-alpha-D-ribose 1''-phosphate + H(+) + nicotinamide


name: Leptin Binds Leptin Receptor (Homo sapiens)


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Sus scrofa)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Plasmodium falciparum)


name: Formation of ORC(2-5) complex (Dictyostelium discoideum)


name: L-gulonate + NAD(+) <=> H(+) + keto-D-fructuronate + NADH


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NADP(+) => CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH


name: PG and CDP-DAG are converted to CL by CRLS1 (Homo sapiens)


name: methanol + o-quinone methide => hydroxyclavatol methyl ether


name: (3R,4R)-7,2'-dihydroxy-4'-methoxyisoflavanol = (-)-medicarpin + H2O


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O <=> (9Z)-octadecenoate + 1,3-di-(9Z-octadecenoyl)-glycerol + H(+)


name: 3,4-dihydroxybenzoate + 2 H(+) + NADPH + O2 <=> benzene-1,2,4-triol + CO2 + H2O + NADP(+)


name: Binding of PI3K to ERBB2:p-ERBB3 heterodimer (Rattus norvegicus)


name: ROBO3.1 antagonizes ROBO1/ROBO2 to allow floor plate crossing (Homo sapiens)


name: METAP1/2 demethylates GNAT1 (Saccharomyces cerevisiae)


name: Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA (Homo sapiens)


name: Amyloid fibrils have additional components (Homo sapiens)


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Sus scrofa)


name: ADP + H(+) + phosphate + prostaglandin E2(out) => ATP + H2O + prostaglandin E2(in)


name: an (S)-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-methionine = an (S)-cis-N-methyl-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-homocysteine


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: 2 oxidized [2Fe-2S]-[ferredoxin] + protochlorophyllide a <=> 3,8-divinyl protochlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Rattus norvegicus)


name: DCP1-DCP2 complex decaps mRNA (Saccharomyces cerevisiae)


name: NR1H2,3, NRIP1 bind the FASN gene (Homo sapiens)


name: ERBB2 promotes PTK6 autophosphorylation (Bos taurus)


name: 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine => 5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine


name: adenosine(4220) in 28S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(4220) in 28S rRNA + S-adenosyl-L-homocysteine


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Bos taurus)


name: Phosphorylation and activation of eIF4B by activated S6K1 (Schizosaccharomyces pombe)


name: ATP + L-valine + N(3)-fumaramoyl-(S)-2,3-diaminopropanoate <=> ADP + dapdiamide A + H(+) + phosphate


name: CXXC1 and WDR82 bind SET1B complex (Caenorhabditis elegans)


name: UDP-glucose is oxidised to UDP-glucuronate (Bos taurus)


name: 2-GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane + H2O => GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Xenopus tropicalis)


name: 15-oxoprostaglandin E2 + H(+) + NADPH => 13,14-dihydro-15-oxo-prostaglandin E2 + NADP(+)


name: a beta-D-GalNAc-(1->4)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer + H(+) + UDP => a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: (9Z,12Z,15Z)-octadecatrien-1-ol + 1-hexadecanoylglycerone 3-phosphate <=> 1-O-(9Z,12Z,15Z)-octadecatrienylglycerone 3-phosphate + H(+) + hexadecanoate


name: Exocytosis of tertiary granule lumen proteins (Plasmodium falciparum)


name: (2R)-3-phosphoglycerate + NAD(+) <=> 3-phosphooxypyruvate + H(+) + NADH


name: Activated NTRK2 binds FRS3 (Homo sapiens)


name: L-lysyl-[citrate synthase] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: TXLNA (IL14) binds syntaxin1A (Mus musculus)


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Bos taurus)


name: glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Drosophila melanogaster)


name: CHIT1 hydrolyses CHIT to 3xADGP (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Rattus norvegicus)


name: (-)-menthol + UDP-alpha-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP


name: TAT aminates HPP (Dictyostelium discoideum)


name: Arachidonate is hydroxylated to 16-HETE by CYP(1) (Homo sapiens)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Rattus norvegicus)


name: H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine <=> 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP


name: ATP + CoA + hexadecanedioate = AMP + diphosphate + hexadecanedioyl-CoA


name: a polyvinyl alcohol + 2n Fe(III)-[cytochrome c] = an oxidized polyvinyl alcohol + 2n Fe(II)-[cytochrome c] + 2n H(+)


name: "polyvinyl alcohol dehydrogenase (cytochrome)"


name: PLK1 hyperphosphorylates Condensin II complex (Caenorhabditis elegans)


name: 6-carboxyhexanoyl-[ACP] + reduced [flavodoxin] => 7-oxoheptanoyl-[ACP] + H2O + oxidized [flavodoxin]


name: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + hydrogen cyanide


name: SLC29A1 transports RBV from cytosol to extracellular region (Homo sapiens)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Sus scrofa)


name: argininosuccinate <=> fumarate + arginine (Schizosaccharomyces pombe)


name: Catabolism of Noradrenaline (Homo sapiens)


name: LC3 binds ATG7 dimer (Caenorhabditis elegans)


name: SUMOylation of HDAC2 with SUMO1 (Dictyostelium discoideum)


name: EP3 subtype prostaglandin E2 receptor binding


name: a short-chain fatty acid + CoA + H(+) => a short-chain fatty acyl-CoA + H2O


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Homo sapiens)


name: 4 A + sn-3-O-phytanylglycerol 1-phosphate = 4 AH2 + sn-3-O-(geranylgeranyl)glycerol 1-phosphate


name: cysteine transmembrane transporter activity


name: lactate transmembrane transporter activity


name: glycyl-L-glutamate(out) + 3 H(+)(out) => glycyl-L-glutamate(in) + 3 H(+)(in)


name: CDK1 phosphorylates MAPK6 (Homo sapiens)


name: MMACHC:cob(II)alamin binds MMADHC (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: 3,6-dichloropyridine-2,5-dione + chloride + FAD + 2 H(+) + H2O => 3,5,6-trichloropyridin-2-ol + FADH2 + O2


name: 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate => L-glutamine + scyllo-inosose


name: N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-alanine => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-alanine + O2


name: glycoursodeoxycholate(out) + 2 Na(+)(out) => glycoursodeoxycholate(in) + 2 Na(+)(in)


name: L-glutamate + sulfoacetaldehyde => 2-oxoglutarate + taurine


name: AMP + H2O => IMP + NH4+ (AMPD) (Rattus norvegicus)


name: NTPDase8 hydrolyzes nucleoside triphosphates (Plasmodium falciparum)


name: a (Z)-glucosinolate + H2O = a (Z)-N-(sulfonatooxy)alkanimidothioate + D-glucose + H(+)


name: Protein Kinase B (AKT) phosphorylates KSRP (Homo sapiens)


name: AURKA phosphorylates PLK1 (Canis familiaris)


name: H(+) + o-quinone methide + peniphenone D => penilactone A


name: 6-hydroxynicotinate + 2 Fe(II)-[cytochrome] + 2 H(+) => 2 Fe(III)-[cytochrome] + H2O + nicotinate


name: ASIC3 channel blockers bind ASIC3 trimer (Rattus norvegicus)


name: p62 is recruited and forms a complex with TRAF6 (Xenopus tropicalis)


name: D-mannose + H(+) + NADH => D-mannitol + NAD(+)


name: glyoxylate + L-tryptophan = glycine + indole-3-pyruvate


name: 6 CO2 + 7 CoA + 2 H2O + nor-toralactone => acetyl-CoA + 6 H(+) + 6 malonyl-CoA


name: Furin cleaves pro-prothrombin to prothrombin (Canis familiaris)


name: IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Homo sapiens)


name: adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate


name: Glucosylation of collagen propeptide hydroxylysines (Bos taurus)


name: Activation of caspase-3 (Rattus norvegicus)


name: NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate + [(1->4)-alpha-D-galacturonosyl](n-2) => [(1->4)-alpha-D-galacturonosyl](n)


name: DBI, ACBD7 bind MCFA-CoA and LCFA-CoA (Dictyostelium discoideum)


name: a quinol + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) => a quinone + reduced coenzyme F420-(gamma-L-Glu)(n)


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H(+)


name: Association of multimerized Rev with beta-importin (Homo sapiens)


name: histone H2AK129 ubiquitin ligase activity


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Sus scrofa)


name: RCHY1 monoubiquitinates POLH (Gallus gallus)


name: PEX7 binds cargo proteins containing PTS2 (Dictyostelium discoideum)


name: (2E)-glutaconyl-CoA + H2O2 => glutaryl-CoA + O2


name: (9Z,12Z)-octadecadienoate + O2 = (2R,9Z,12Z)-2-hydroperoxyoctadecadienoate


name: PC is converted to PS by PTDSS1 (Rattus norvegicus)


name: (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA + NADP(+) => (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + H(+) + NADPH


name: H(+)(in) + L-histidine(in) => H(+)(out) + L-histidine(out)


name: 2-oxopent-4-enoate + formate + H(+) => (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Canis familiaris)


name: (deoxy)uridine + orthophosphate <=> uracil + (deoxy)ribose 1-phosphate (UPP) (Plasmodium falciparum)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H(+)


name: H(+) + NADPH + O2 + protoviolaceinate => H2O + NADP(+) + violaceinate


name: (-)-yatein + 2-oxoglutarate + O2 => (-)-deoxypodophyllotoxin + CO2 + H2O + succinate


name: H(+)(in) + taurine(in) => H(+)(out) + taurine(out)


name: 2'-deoxyadenosine + phosphate => dAMP + H2O


name: EP300 is recruited to MYC and BCL2 genes (Drosophila melanogaster)


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Canis familiaris)


name: PPM1E dephosphorylates CAMK4 (Homo sapiens)


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Dictyostelium discoideum)


name: yaequinolone D => [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B


name: SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Bos taurus)


name: biphenyl-2,3-diol + H(+) + NADH => (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: Dopa is decarboxylated to dopamine (Danio rerio)


name: Further sulfation on galactose residues produces KSPG (Drosophila melanogaster)


name: TCF7L2:CTNNB1, EOMES, TBXT, MIXL1, SMAD2,3, FOXA2, GATA4, and GATA6 bind the SOX17 gene (Homo sapiens)


name: RAC2 translocates to the mitochondrial membrane (Rattus norvegicus)


name: 3-[(1-carboxyvinyl)-oxy]benzoate + H2O => chorismate


name: Ethylene is oxidized to Ethylene oxide by CYP1A1 (Bos taurus)


name: p-S207 KARS1 dimer translocates to the nucleus (Drosophila melanogaster)


name: SFTPA/SFTPD binds TLR2:TLR1 (Rattus norvegicus)


name: (S)-dihydroorotate + ubiquinone-8 <=> orotate + ubiquinol-8


name: 2-dehydro-D-glucose + H2O2 + L-alanine => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-alanine + O2


name: NICD4 traffics to the nucleus (Homo sapiens)


name: 4-hydroxybenzoate + H(+) + phosphate => CO2 + H2O + phenyl phosphate


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Danio rerio)


name: BCAP Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Bos taurus)


name: a fatty acid ester + H2O = a fatty acid + an aliphatic alcohol + H(+)


name: ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Canis familiaris)


name: Co(I)-[methylamine-specific corrinoid protein] + H(+) + methylamine => methyl-Co(III)-[methylamine-specific corrinoid protein] + NH4(+)


name: NRXNs bind NLGNs (Caenorhabditis elegans)


name: apo-[aequorin] + coelenterazine = apo-[aequorin]--coelenterazine


name: calcidiol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = calcitriol + H2O + 2 oxidized [adrenodoxin]


name: TOPORS SUMOylates SIN3A with SUMO1 (Mus musculus)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Xenopus tropicalis)


name: IRAK2 induces TRAF6 oligomerization (Homo sapiens)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Xenopus tropicalis)


name: 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 (Danio rerio)


name: CoA(in) + FAD(out) => CoA(out) + FAD(in)


name: Pancreatic proteases degrade TCN1:RCbl (Homo sapiens)


name: RUNX3 binds the NOTCH1 coactivator complex (Mus musculus)


name: methanol + N,N-dimethyl-4-nitrosoaniline = 4-(hydroxylamino)-N,N-dimethylaniline + formaldehyde


name: DHX36 or DHX9 binds MyD88 (Gallus gallus)


name: (9Z,12Z)-octadecadienoate + O2 => (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication


name: O-phospho-L-serine + thiosulfate = phosphate + S-sulfo-L-cysteine


name: ABCE1 binds RNASEL, inhibiting it (Mus musculus)


name: 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose = 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+)


name: Thiolysis of 3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA yields choloyl-CoA (3alpha,7alpha,12alpha-trihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Drosophila melanogaster)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Homo sapiens)


name: RAC1 GAPs stimulate RAC1 GTPase activity (Dictyostelium discoideum)


name: (Z)-24-ethylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 <=> 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: rRNA (pseudouridine) methyltransferase activity


name: EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)


name: Caspase mediated cleavage of alpha-II-Fodrin (Rattus norvegicus)


name: Translocation of tBID to mitochondria (Mus musculus)


name: Aquaporin-7 passively transports glycerol out of cell (Sus scrofa)


name: Activated FGFR3 phosphorylates PPTN11 (Danio rerio)


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-dodecanoyl-sn-glycerol + H(+) + phosphocholine


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Xenopus tropicalis)


name: Cleaved KMT2A dimers translocate to the nucleus (Xenopus tropicalis)


name: sphing-4-enine + UDP-alpha-D-galactose <=> beta-D-galactosyl-(1<->1)-sphing-4-enine + H(+) + UDP


name: H2O + N(6)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2 => (1-deoxy-D-fructos-1-yl)amine + (S)-2-amino-6-oxohexanoate + H2O2


name: Addition of galactose by beta 4-galactosyltransferases (Gallus gallus)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Sus scrofa)


name: a tetracycline + H(+) + NADPH + O2 = a (1S,10aS)-3-(CONH2)-1-(Me2N)-3,3a,4,6-(HO)4-2,5-dioxo-1H,10aH,11H,11aH-cyclopenta[b]anthracene + CO + H2O + NADP(+)


name: DENND5A,B exchange GTP for GDP on RAB39 (Gallus gallus)


name: Ubiquitinated TP53 translocates to the cytosol (Canis familiaris)


name: (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate => goitrin + sulfate


name: H(+) + NADPH + O2 + tryprostatin B = demethoxyfumitremorgin C + 2 H2O + NADP(+)


name: gypsogenate + UDP-alpha-D-glucose = gypsogenate 28-beta-D-glucoside + UDP


name: 1-octadecanoylglycerone 3-phosphate + hexadecan-1-ol => 1-O-hexadecylglycerone 3-phosphate + H(+) + octadecanoate


name: p-6Y-SYK phosphorylates BLNK (SLP65) (Homo sapiens)


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Gallus gallus)


name: 2 Fe(III)-[cytochrome b5] + NADPH => 2 Fe(II)-[cytochrome b5] + H(+) + NADP(+)


name: Expression of capping actin protein of muscle Z-line alpha subunit 1 (Homo sapiens)


name: Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG (Gallus gallus)


name: MRE11 binds cytosolic DNA (Plasmodium falciparum)


name: Trafficking of GluR2-containing AMPA receptors to synapse (Rattus norvegicus)


name: Phosphorylated GAB1 recruits PI3K to MET (Xenopus tropicalis)


name: 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP(+) => acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH


name: Androgens binds AR (in the HSP90 chaperone complex) (Xenopus tropicalis)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Bos taurus)


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Gallus gallus)


name: ATP2B4 binds to NOS1, inhibiting it (Schizosaccharomyces pombe)


name: Excess homocysteine yields homolanthionine and H2S (Sus scrofa)


name: (R)-1-phenylethanol + NADP(+) => acetophenone + H(+) + NADPH


name: (2Z,6E)-farnesyl diphosphate = diphosphate + gamma-cadinene


name: 2 glutathione + thiosulfate => glutathione disulfide + 2 H(+) + hydrogen sulfide + sulfite


name: ARV1 transports CHOL from ER membrane to plasma membrane (Homo sapiens)


name: Activation of RAC1 by VAV2/3 (Mus musculus)


name: 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol


name: sunitinib-resistant FLT3 mutants don't bind sunitinib (Homo sapiens)


name: ABC7, mABC1 and mABC2 mediate heme transport (Mus musculus)


name: Release of E3 from polyubiquitinated substrate (Plasmodium falciparum)


name: 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH => 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: 16beta,17beta-estriol + UDP-alpha-D-glucuronate = 16beta,17beta-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: a medium-chain (2E)-enoyl-CoA + H2O2 => a medium-chain 2,3-saturated fatty acyl-CoA + O2


name: Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK (Homo sapiens)


name: (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA + H(+) + NADPH = (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+)


name: p-S207 KARS1 dimer translocates to the nucleus (Dictyostelium discoideum)


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Mus musculus)


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Gallus gallus)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 (Bos taurus)


name: pro-SFTPB translocates from ER membrane to multivesicle body (Gallus gallus)


name: Formation of the 43S pre-initiation complex (Sus scrofa)


name: glyoxal + L-arginyl-[protein] <=> N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein]


name: 3,5-dimethylcyclohexanamine + H2O + NADP(+) => 3,5-dimethylcyclohexanone + H(+) + NADPH + NH4(+)


name: (2S)-naringenin + 2-oxoglutarate + O2 => apigenin + CO2 + H(+) + H2O + succinate


name: (5S)-C-methyl-L-arginyl-[methyl-coenzyme M reductase] + 5'-deoxyadenosine + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine => AH2 + L-arginyl-[methyl-coenzyme M reductase] + 2 S-adenosyl-L-methionine


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Schizosaccharomyces pombe)


name: CoA + H(+) + N-octadecanoylsphing-4-enine => octadecanoyl-CoA + sphing-4-enine


name: Lsm1-7 Complex binds deadenylated mRNA (Bos taurus)


name: GTP => cyclic pyranopterin phosphate + diphosphate


name: D-ribulose 1,5-bisphosphate => alpha-D-ribose 1,5-bisphosphate


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Xenopus tropicalis)


name: NMNAT2 transfers an adenylyl group from ATP to NMN to yield NAD+ (Homo sapiens)


name: Transfer of sulfur from MOCS3-S-S onto MOCS2A (Homo sapiens)


name: CBL ubiquitinates FRS2 and FGFR3 (Sus scrofa)


name: Activated FGFR4 phosphorylates FRS2 (Bos taurus)


name: p38 MAPK activation by VEGFR (Gallus gallus)


name: a 1-acyl-sn-glycero-3-phosphate + a fatty acid + H(+) => a 1,2-diacyl-sn-glycero-3-phosphate + H2O


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Sus scrofa)


name: Association of procollagen type II (Sus scrofa)


name: Activation of BAD by calcineurin (Sus scrofa)


name: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 <=> 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H(+) + H2O


name: L-arginyl-L-alpha-amino acid(out) = L-arginyl-L-alpha-amino acid(in)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Saccharomyces cerevisiae)


name: ZnT8 transports zinc into the Golgi apparatus (Canis familiaris)


name: anthranilate + H(+) + pyruvate => (2S)-2-amino-4-deoxychorismate


name: CXXC1 and WDR82 bind SET1B complex (Canis familiaris)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> ent-copalyl diphosphate


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Canis familiaris)


name: H(+) + methylglyoxal + NADPH => hydroxyacetone + NADP(+)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Xenopus tropicalis)


name: Exocytosis of specific granule membrane proteins (Mus musculus)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Schizosaccharomyces pombe)


name: UDP + wogonin 7-O-beta-D-glucuronate => UDP-alpha-D-glucuronate + wogonin


name: devancoaminyl-vancomycin + dTDP-beta-L-vancosamine => dTDP + epivancomycin + H(+)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Drosophila melanogaster)


name: dodecanal + H2O + NAD(+) => dodecanoate + 2 H(+) + NADH


name: (S)-N-methylcoclaurine + H(+) + S-adenosyl-L-homocysteine => (S)-coclaurine + S-adenosyl-L-methionine


name: (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+)


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP => 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: Degradation of multiubiquitinated Cyclin B (Canis familiaris)


name: C3d-complexed antigen binds to complement receptor (Homo sapiens)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Saccharomyces cerevisiae)


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Homo sapiens)


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Bos taurus)


name: Conversion of malonyl-CoA and acetyl-CoA to palmitate (Homo sapiens)


name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (Sus scrofa)


name: adenosine 2'-phosphate + H2O => adenosine + phosphate


name: Receptor FFAR1 binds free fatty acids (Mus musculus)


name: GPR35 binds kynurenic acid (Caenorhabditis elegans)


name: WNTs bind the FZD receptor to initiate PCP pathway (Homo sapiens)


name: benzoyl-CoA + octan-1-ol = CoA + octyl benzoate


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Rattus norvegicus)


name: 2 nataloe emodin + O2 + reduced [NADPH--hemoprotein reductase] <=> cladofulvin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Rattus norvegicus)


name: (10bR,4aS)-oxomaritidine + NADP(+) => (10bR,4aS)-noroxomaritidine + H(+) + NADPH


name: NADPH + 2 nitric oxide + 2 O2 <=> H(+) + NADP(+) + 2 nitrate


name: 7-oxolithocholate + H(+) + NADPH <=> NADP(+) + ursodeoxycholate


name: 5-methylsulfanyl-2,3-dioxopentyl phosphate = 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate


name: (20S)-ginsenoside Rd + 2 H2O = (20S)-ginsenoside C-K + 2 D-glucose


name: 2-methoxy-6-all-trans-nonaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine <=> 6-methoxy-3-methyl-2-all-trans-nonaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: DENND3 exchanges GTP for GDP on RAB12 (Bos taurus)


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Canis familiaris)


name: H(+) + L-2,4-diaminobutanoate => CO2 + propane-1,3-diamine


name: beta-catenin is replaced by repression complexes at the promoter (Sus scrofa)


name: 12-hydroxydihydrochelirubine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dihydrochelirubine + O2 + reduced [NADPH--hemoprotein reductase]


name: (7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate


name: D-loop extension by DNA polymerases (Gallus gallus)


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Mus musculus)


name: PKR inhibitors bind PKR (Drosophila melanogaster)


name: RGS proteins bind GNB5 and CCT/TRiC (Homo sapiens)


name: Association of Securin with Cdc20:APC/C complex (Mus musculus)


name: Bile salts dissociate from FABP6 (Xenopus tropicalis)


name: (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + H2O


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Xenopus tropicalis)


name: D-maltoheptaose + H2O <=> alpha-D-glucose + D-maltohexaose


name: Indirect recruitment of GAB2 to p-KIT (Canis familiaris)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + AH2 + O2 <=> 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + A + H2O


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Rattus norvegicus)


name: Oligomerization of BCL10 and MALT1 (Homo sapiens)


name: 3-oxoisoapionate + ATP <=> 3-oxoisoapionate 4-phosphate + ADP + H(+)


name: SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Xenopus tropicalis)


name: chrysoeriol + H(+) + S-adenosyl-L-homocysteine => luteolin + S-adenosyl-L-methionine


name: XIAP dissociates from ub-TLE (Sus scrofa)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Bos taurus)


name: 2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer (Rattus norvegicus)


name: SALL4 recruits NuRD to PTEN gene (Drosophila melanogaster)


name: Edited Kainate Receptor binds glutamate (Rattus norvegicus)


name: p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Homo sapiens)


name: RAC1 GDIs block activation of RAC1 (Rattus norvegicus)


name: Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Drosophila melanogaster)


name: LIPT2 transfers octanoyl group to GCSH (Sus scrofa)


name: acetyl-CoA + AH2 + 3 H(+) + 4 malonyl-CoA + S-adenosyl-L-methionine => 2,4-dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde + A + 4 CO2 + 5 CoA + H2O + S-adenosyl-L-homocysteine


name: AH2 + yaequinolone E => A + peniprequinolone


name: cholesterol + H(+) + NADPH + O2 => 25-hydroxycholesterol + H2O + NADP(+)


name: quercetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose => H(+) + quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP


name: PLK1 binds phosphorylated condensin II complex (Mus musculus)


name: L-xylopyranose(out) + 2 Na(+)(out) = L-xylopyranose(in) + 2 Na(+)(in)


name: Active G alpha (q) binds RGS proteins (Danio rerio)


name: LCAT + spherical HDL <=> LCAT:spherical HDL complex (Sus scrofa)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Danio rerio)


name: 2-oxohexanoate + N(omega),N(omega)-dimethyl-L-arginine <=> 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminohexanoate


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Canis familiaris)


name: RNF8 and RNF168 ubiquitinate H2AFX (Homo sapiens)


name: (3R)-hydroxy-(13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + NADP(+) => (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + H(+) + NADPH


name: 3-bromo-2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine => 3-bromo-2-heptyl-1-methoxy-4(1H)-quinolinone + H(+) + S-adenosyl-L-homocysteine


name: chlorophyllide a + 2 H(+) + 2 NADPH + 2 O2 => chlorophyllide b + 3 H2O + 2 NADP(+)


name: COL1A2 gene expression is stimulated by p-2S-SMAD3:p-2S-SMAD3:SMAD4 (Homo sapiens)


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O <=> beta-D-glucose + N-hexadecanoylsphing-4-enine


name: MADD exchanges GTP for GDP on RAB27 (Bos taurus)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Rattus norvegicus)


name: Delta(1)-piperideine-2-carboxylate + H(+) + NADH => L-pipecolate + NAD(+)


name: Phosphorylated RHOU translocates to the endosome membrane (Sus scrofa)


name: H2O + L-methionine + O2 = 4-methylsulfanyl-2-oxobutanoate + H2O2 + NH4(+)


name: acetyl-CoA + horhammericine <=> 19-O-acetylhorhammericine + CoA


name: 17beta-estradiol + O2 + reduced [NADPH--hemoprotein reductase] <=> 6alpha-hydroxy-17beta-estradiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AKT phosphorylates caspase-9 (Drosophila melanogaster)


name: Phosphorylated heterodimers of ERBB2 KD mutants bind SHC1 (Homo sapiens)


name: BTN2A1 binds DC-SIGN (Xenopus tropicalis)


name: Formation of the CTF18 complex (Caenorhabditis elegans)


name: GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Homo sapiens)


name: (1R,3R)-pyrethroyl-CoA + (Z,S)-cinerolone => cinerin II + CoA


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Drosophila melanogaster)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Homo sapiens)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Xenopus tropicalis)


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => (22R)-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Active FLT3 binds to SH2B3 (Mus musculus)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Drosophila melanogaster)


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + ADP + H(+) => (2R)-3-phosphoglycerate + ADP-alpha-D-glucose


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Saccharomyces cerevisiae)


name: (2E,6E)-farnesyl diphosphate + H2O <=> (+)-corvol ether A + diphosphate


name: 17beta-hydroxy-5alpha-androstan-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 17beta,18-dihydroxy-3-oxo-5alpha-androstanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a long-chain fatty acid + ATP + H(+) <=> a long-chain fatty acyl-AMP + diphosphate


name: Kinesins move along microtubules consuming ATP (Gallus gallus)


name: (9Z,12Z,15Z)-octadecatrienoate + H2O => (12Z,15Z)-10-hydroxyoctadecadienoate


name: (9Z)-octadecenoyl-CoA + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine <=> 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Drosophila melanogaster)


name: PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: 2-oxopentanoate + L-kynurenine <=> H2O + kynurenate + L-2-aminopentanoate


name: mannitol 2-dehydrogenase (NADP+) activity


name: 3 H(+) + N-terminal N,N,N-trimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-homocysteine => N-terminal glycyl-L-lysyl-L-glutamyl-[protein] + 3 S-adenosyl-L-methionine


name: Formation of the 19S regulatory particle base precursor (Caenorhabditis elegans)


name: GMP + NADPH + H+ => IMP + NADP+ + NH4+ (GMPR,GMPR2) (Bos taurus)


name: N(5)-hydroxy-L-ornithine <=> (3S)-1,2-diazinane-3-carboxylate + H(+) + H2O


name: CHSY1 transfers GlcA to chondroitin (Danio rerio)


name: 3'-phosphoadenylyl sulfate + glycochenodeoxycholate <=> adenosine 3',5'-bisphosphate + glycochenodeoxycholate 7-sulfate + H(+)


name: Follicle-stimulating hormone receptor can bind FSH (Gallus gallus)


name: Nephrin trans-homophilic interaction (Drosophila melanogaster)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Rattus norvegicus)


name: (2R,3S,4S)-3,4-leucopelargonidin + 2-oxoglutarate + O2 = (4S)-2,3-dehydroleucopelargonidin + CO2 + H(+) + H2O + succinate


name: NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Mus musculus)


name: WWTR1 (TAZ) binds TEAD (Xenopus tropicalis)


name: RPS6KA1-dependent phosphorylation of MITF-M (Rattus norvegicus)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Saccharomyces cerevisiae)


name: 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol + S-adenosyl-L-methionine = H(+) + plastoquinol-9 + S-adenosyl-L-homocysteine


name: adenosine(1914)/adenosine(1915) in 18S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1914)/N(6)-dimethyladenosine(1915) in 18S rRNA + 4 S-adenosyl-L-homocysteine


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Xenopus tropicalis)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Caenorhabditis elegans)


name: Cleavage of ethenocytosine by TDG glycosylase  (Canis familiaris)


name: Spherical HDL binds C and E apolipoproteins (Sus scrofa)


name: p-S256-Aquaporin-2 passively transports water into cell (Sus scrofa)


name: alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity


name: Dephosphorylated SMAD2/3 translocates to the cytosol (Caenorhabditis elegans)


name: Phosphorylation and activation of eIF4B by activated S6K1 (Bos taurus)


name: 2 gamma-L-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH


name: 4-nitrophenol + H(+) + phosphate => 4-nitrophenyl phosphate + H2O


name: phosphate + ribitol => D-ribitol 5-phosphate + H2O


name: Activation of RAC1 by VAV2/3 (Xenopus tropicalis)


name: 3-[(3S)-3-amino-3-carboxypropyl]uridine(47) in tRNA(Phe) + H(+) + S-methyl-5'-thioadenosine => S-adenosyl-L-methionine + uridine(47) in tRNA(Phe)


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Bos taurus)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Canis familiaris)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Dictyostelium discoideum)


name: 24,25-dihydrolanosterol + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: (E)-cinnamoyl-CoA + (R)-3-phenyllactate = (E)-cinnamate + (R)-3-phenyllactoyl-CoA


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Gallus gallus)


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Dictyostelium discoideum)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Rattus norvegicus)


name: XPO1 binds p-S69,73 MITF-M (Rattus norvegicus)


name: PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Homo sapiens)


name: POU3F1 binds the ZNF521 gene (Homo sapiens)


name: AQP1 tetramer transports CO2 from cytosol to extracellular region (Canis familiaris)


name: Cleavage of the 3'-end of Replication Dependent Histone Pre-mRNA (Mus musculus)


name: AMP(in) + FAD(out) => AMP(out) + FAD(in)