name: LMAN family proteins bind glycosylated cargo (Rattus norvegicus)


name: D-histidine + S-adenosyl-L-methionine = (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + S-methyl-5'-thioadenosine


name: ALOX12 oxidises LTA4 to LXB4 (Homo sapiens)


name: 4-hydroxy-6-methylpretetramide + NADPH + O2 = 4-dedimethylamino-4-oxo-anhydrotetracycline + H2O + NADP(+)


name: eNOS:Caveolin-1 complex binds to Nostrin (Rattus norvegicus)


name: a (3R)-hydroxyacyl-[ACP] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose => a UDP-2-acetamido-3-{[(3R)-3-hydroxyacyl]amino}-2,3-dideoxy-alpha-D-glucopyranose + H(+) + holo-[ACP]


name: tubulin N-terminal N-acetyltransferase activity


name: H2O + L-serine-phosphoethanolamine = H(+) + L-serine + phosphoethanolamine


name: NICD1 is phosphorylated by CDK8 (Homo sapiens)


name: PKCalpha phosphorylates HuR (Drosophila melanogaster)


name: D-glucono-1,5-lactone + H(+) + NADPH => D-glucose + NADP(+)


name: Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Sus scrofa)


name: NTPDase1 hydrolyzes nucleoside diphosphates (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: TXNIP binds reduced thioredoxin (Caenorhabditis elegans)


name: 1-acyl LPS is acylated to PS by LPSAT (Xenopus tropicalis)


name: 6alpha-hydroxy-28-norteasterone + O2 + reduced [NADPH--hemoprotein reductase] => 28-norteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Mus musculus)


name: unsaturated chondroitin disaccharide hydrolase activity


name: 3-methoxybenzoate + ATP + H(+) + NADPH = 3-methoxybenzaldehyde + AMP + diphosphate + NADP(+)


name: CDC42 and PIP2 bind WASL, activating it (Gallus gallus)


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Canis familiaris)


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Sus scrofa)


name: acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose = CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + H(+)


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Homo sapiens)


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Homo sapiens)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Bos taurus)


name: Tankyrase ADP-ribosylates AXIN (Sus scrofa)


name: TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Xenopus tropicalis)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Bos taurus)


name: H(+) + NADPH + sepiapterin => L-erythro-7,8-dihydrobiopterin + NADP(+)


name: HuR binds the CRM1 nuclear export machinery (Sus scrofa)


name: (2-hydroxyphenyl)acetate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 2-phenylacetate + O2 + reduced [NADPH--hemoprotein reductase]


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: 5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate => 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine


name: a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-threonyl-[protein] <=> 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Sus scrofa)


name: SARS-CoV-1 nsp1 binds to PPIase (Homo sapiens)


name: (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein] <=> AMP + 2 H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein]


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Canis familiaris)


name: Pol II elongation complex moves on the template as transcript elongates (Homo sapiens)


name: PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) (Mus musculus)


name: 6 Fe(II)-[cytochrome c] + 8 H(+) + nitrite => 6 Fe(III)-[cytochrome c] + 2 H2O + NH4(+)


name: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O => L-threonyl-[protein] + N-acetyl-D-galactosamine


name: ATP + H2O + N-[(S)-lactoyl]-L-phenylalanine(in) => ADP + H(+) + N-[(S)-lactoyl]-L-phenylalanine(out) + phosphate


name: PRC2 trimethylates histone H3 at lysine-27 (Gallus gallus)


name: acetylcholine-gated monoatomic cation-selective channel activity


name: Activated FGFR3 phosphorylates SHC1 (Bos taurus)


name: TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Xenopus tropicalis)


name: ATP + citrate + L-glutamate => ADP + beta-citrylglutamate + H(+) + phosphate


name: benzene-1,2,4-triol + O2 = 2 H(+) + maleylacetate


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Drosophila melanogaster)


name: CTNNBIP1 binds beta-catenin (Sus scrofa)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Homo sapiens)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Homo sapiens)


name: CDK1:CCNB phosphorylates NEK9 (Rattus norvegicus)


name: 1D-myo-inositol 1,4,5-trisphosphate + 2 ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 2 ADP + 2 H(+)


name: (R)-noradrenaline + H2O + O2 => (R)-3,4-dihydroxymandelaldehyde + H2O2 + NH4(+)


name: PIAS4 SUMOylates PPARA with SUMO1 (Mus musculus)


name: a 1,2-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol


name: branched-chain amino acid transmembrane transporter activity


name: SLC25A44 transports Leu, Ile and Val from cytosol to mitochondrial matrix (Homo sapiens)


name: 2-deoxy-D-ribose 5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+) => a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA + H2O


name: CD55 (DAF) binds C3bBb, C4bC2a (Bos taurus)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Drosophila melanogaster)


name: (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine => S-(5-deoxy-D-ribos-5-yl)-L-homocysteine


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Gallus gallus)


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Xenopus tropicalis)


name: DMBT1 binds SFTPD 12mer, SFTPAs (Homo sapiens)


name: ORC6 is phosphorylated on T195 (Sus scrofa)


name: (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + H2O <=> (-)-geosmin


name: SPHK2 phosphorylates sphingoid (Canis familiaris)


name: ATP + H2O + indoxyl sulfate(in) <=> ADP + H(+) + indoxyl sulfate(out) + phosphate


name: CYP1B1 4-hydroxylates EST17b (Mus musculus)


name: Tenascins C, R, (X, N) bind lecticans (Danio rerio)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 = (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate


name: HMGCR dimer binds statins (Schizosaccharomyces pombe)


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Canis familiaris)


name: 3-hydroxy-L-kynurenine(out) + L-tryptophan(in) <=> 3-hydroxy-L-kynurenine(in) + L-tryptophan(out)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Drosophila melanogaster)


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Bos taurus)


name: D-arabinono-1,4-lactone + H2O => D-arabinonate + H(+)


name: O2 + proatranorin II + reduced [NADPH--hemoprotein reductase] <=> H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + proatranorin III


name: a ganglioside GM2 + H(+) + UDP => a ganglioside GM3 + UDP-N-acetyl-alpha-D-galactosamine


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacylglycerol => 1-O-alkyl-sn-glycero-3-phosphocholine + a triacylglycerol


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Homo sapiens)


name: methylenetetrahydrofolate reductase (NADH) activity


name: 6-carboxyhex-2-enoyl-CoA + H(+) + NADH => 6-carboxyhexanoyl-CoA + NAD(+)


name: AH2 + androst-4-ene-3,17-dione + O2 => A + H2O + testololactone


name: AMP + diphosphate + L-glutamyl-tRNA(Gln) => ATP + L-glutamate + tRNA(Gln)


name: 3-hydroxyanthranilate + O2 => (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Dictyostelium discoideum)


name: a cytidine in RNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in RNA + H(+) + S-adenosyl-L-homocysteine


name: ATP + H2O + L-selenomethionine => diphosphate + L-adenosylselenomethionine + phosphate


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Gallus gallus)


name: dehydrogriseofulvin + H(+) + NADPH => griseofulvin + NADP(+)


name: P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Homo sapiens)


name: 3-oxooctanoyl-CoA + H(+) + NADH => (3S)-hydroxyoctanoyl-CoA + NAD(+)


name: (+)-alpha-santalene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: 2alpha-hydroxyl, 4beta-carboxyl motiol + 4 O2 + 4 reduced [NADPH--hemoprotein reductase] <=> 5 H(+) + 5 H2O + 4 oxidized [NADPH--hemoprotein reductase] + polytolypin


name: maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) (Dictyostelium discoideum)


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)


name: DREAM complex binds the CDC6 gene promoter (Homo sapiens)


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Rattus norvegicus)


name: D-ribono-1,4-lactone + H(+) + NADH = D-ribose + NAD(+)


name: Activated FGFR1 phosphorylates FRS2 (Mus musculus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => diphosphate + fusoxypene A


name: TBC1D25 accelerates GTP hydrolysis by RAB33B (Sus scrofa)


name: (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one <=> (3R)-3-isopropenyl-6-oxoheptanoate + H(+)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Homo sapiens)


name: uridine(746) in 23S rRNA <=> pseudouridine(746) in 23S rRNA


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Xenopus tropicalis)


name: L-histidyl-[protein] + S-adenosyl-L-methionine = H(+) + N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine


name: cochalate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + oleanolate + reduced [NADPH--hemoprotein reductase]


name: CDK1 phosphorylates MAPK6 (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate = diphosphate + sibirene


name: 3,3',5'-triiodo-L-thyronine + A + H(+) + iodide => AH2 + L-thyroxine


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Danio rerio)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Bos taurus)


name: RNF41 ubiquitinates ERBB3 (Rattus norvegicus)


name: hydrogencarbonate(in) + selenite(in) + Zn(2+)(in) => hydrogencarbonate(out) + selenite(out) + Zn(2+)(out)


name: MRAS:SHOC2:PPP1CC dephosphorylates inactive RAFs (Gallus gallus)


name: coenzyme B + methyl-coenzyme M <=> coenzyme M-coenzyme B heterodisulfide + methane


name: chloride + FADH2 + ilicicolin B + O2 <=> FAD + H(+) + 2 H2O + ilicicolin A


name: (+)-copalyl diphosphate => abieta-7,13-diene + diphosphate


name: cinnamaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+) => cinnamyl alcohol + 2 Fe(III)-[cytochrome c]


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Homo sapiens)


name: KLK5 cleaves and activates CELA2 (Mus musculus)


name: RTC binds SARS-CoV-2 genomic RNA complement (minus strand) (Homo sapiens)


name: trans-Golgi Network Coat Activation (Canis familiaris)


name: Binding of ADAR2 homodimer to dsRNA duplex (Caenorhabditis elegans)


name: (S)-lactaldehyde + dihydroxyacetone phosphate => L-rhamnulose 1-phosphate


name: Active FLT3:GRB2 binds SOS1 (Sus scrofa)


name: hydrogencarbonate + NH4(+) => carbamate + H(+) + H2O


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: DHFR dimer reduces FOLA to DHF (Bos taurus)


name: dTDP-L-dihydrostreptose + streptidine 6-phosphate => dTDP + H(+) + O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Homo sapiens)


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Homo sapiens)


name: Autophosphorylation and activation of CAMK2 (Sus scrofa)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Canis familiaris)


name: PM20D1 hydrolyzes oleoyl-phe (Schizosaccharomyces pombe)


name: Androgens binds AR (in the HSP90 chaperone complex) (Bos taurus)


name: RAC3 GDIs block activation of RAC3 (Sus scrofa)


name: Formation of the PA28-alpha-beta-20S proteasome (Bos taurus)


name: SLC22A1 transports Cipro into renal cell (Danio rerio)


name: TTP(in) + UTP(out) => TTP(out) + UTP(in)


name: a jasmonyl-L-amino acid + H2O = a jasmonate + an L-alpha-amino acid


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Rattus norvegicus)


name: CUL5 mediates ubiquitination of ERBB2 (Homo sapiens)


name: GDP-beta-L-fucose + Lc4Cer => alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + GDP + H(+)


name: p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol (Rattus norvegicus)


name: temperature-gated cation channel activity


name: Caspase-mediated cleavage of Rock-1 (Bos taurus)


name: Mitochondrial RNase P (mtRNase P) cleaves the 5' ends of pre-tRNAs and ELAC2 (RNase Z) cleaves the 3' ends of pre-tRNAs in the L strand transcript (Homo sapiens)


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Mus musculus)


name: biopterin transmembrane transporter activity


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: CYP2D6 4-hydroxylates debrisoquine (Homo sapiens)


name: DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Bos taurus)


name: NAPSA, CTSH, PGA3-5 cleave pro-SFTPB (Bos taurus)


name: 2-dehydro-L-idonate + H(+) + NADH => L-idonate + NAD(+)


name: Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Drosophila melanogaster)


name: ST6GAL1 transfers Neu5Ac to terminal Gal of N-glycans (Xenopus tropicalis)


name: chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] <=> alpha-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR (Bos taurus)


name: GUCA binds Ca2+ to form GUCA:Ca2+ (Bos taurus)


name: [(2->6)-alpha-D-glucosyl-(1->4)-N,7-O-diacetyl-alpha-D-neuraminosyl](n) + n CoA => [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA


name: B4GALTs transfer Gal to the keratan chain (Drosophila melanogaster)


name: (2S)-2-aminobutanoate + 2-oxo-3-sulfanylpropanoate => 2-oxobutanoate + L-cysteine


name: PAK1 or PAK2 phosphorylates MYLK (Mus musculus)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Danio rerio)


name: FADH2 + O2 + phenol = catechol + FAD + H(+) + H2O


name: Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Gallus gallus)


name: HGD dioxygenates homogentisate (Caenorhabditis elegans)


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Xenopus tropicalis)


name: 2 sucrose = 6-kestotriose + beta-D-glucose


name: PRC1 SUMOylates CASP8AP2 with SUMO1 (Bos taurus)


name: Formation of active mTORC1 complex (Bos taurus)


name: IL20:IL20RA:JAK1:IL20RB:p‑JAK2,p‑JAK3 binds STAT3 (Bos taurus)


name: HuR binds the CRM1 nuclear export machinery (Drosophila melanogaster)


name: PI is exchanged with PC by PITPNB (Sus scrofa)


name: STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Rattus norvegicus)


name: ATP + thiamine <=> AMP + H(+) + thiamine diphosphate


name: cis-(homo)3aconitate + H2O = (2R,3S)-iso(homo)3citrate


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(in) + ATP + H2O <=> 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(out) + ADP + H(+) + phosphate


name: SCF betaTrCP ubiquitinates NFKB p105 within p-S927, S932-NFkB p105:TPL2:ABIN2  (Xenopus tropicalis)


name: (d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Caenorhabditis elegans)


name: (2R,3R)-2,3-dihydrogossypetin + H2O + NADP(+) => (2R,3R)-dihydroquercetin + H(+) + NADPH + O2


name: kininogen + C1q binding protein tetramer -> kininogen:C1q binding protein tetramer (Homo sapiens)


name: Formation of the MLL4 complex (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + hexadecanoate


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Sus scrofa)


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Dictyostelium discoideum)


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + 3 S-adenosyl-L-methionine <=> 3,8-divinyl protochlorophyllide a + 3 5'-deoxyadenosine + 4 H(+) + 3 L-methionine


name: MITF-M dimer binds MLANA gene (Homo sapiens)


name: Phosphorylation of PTK2 (FAK) on tyrosine-397 in response to turbulent blood flow (Gallus gallus)


name: a (2E)-enoyl fatty acid + ATP + H(+) <=> a (2E)-2-fatty-enoyl-AMP + diphosphate


name: Dimerization of Phospho-IRF3 (Gallus gallus)


name: dodecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-undecylpyran-2-one + 2 CO2 + 3 CoA


name: Cross-linking of FCGRIA with IgG-coated Ag (Mus musculus)


name: H2O + L-serine + NAD(+) => 3-hydroxypyruvate + H(+) + NADH + NH4(+)


name: PDE6D dissociates from ARL13B:INPP5E (Homo sapiens)


name: Activation of Calcineurin (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)


name: AGK:Mg2+ phosphorylates MAG, DAG (Caenorhabditis elegans)


name: a 2-acyl-sn-glycero-3-phospho-L-serine + H2O <=> a 2-acyl-sn-glycerol 3-phosphate + H(+) + L-serine


name: NEDD4L ubiquitinates SMAD2/3 (Mus musculus)


name: 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol <=> [thioredoxin]-disulfide + H(+) + hydrogen sulfide + pyruvate


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Rattus norvegicus)


name: SLC38A9 transports L-Arg from lysosomal lumen to cytosol (Sus scrofa)


name: (S)-acetoin + NAD(+) <=> diacetyl + H(+) + NADH


name: apigenin + UDP-alpha-D-glucose => H(+) + isovitexin + UDP


name: a very-long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein] => a very-long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: DHAP is converted to G3P by GPD1/GPD1L (Xenopus tropicalis)


name: 2 L-ascorbate + N-decanoylglycine + O2 <=> H2O + 2 monodehydro-L-ascorbate radical + N-decanoyl-(2S)-hydroxyglycine


name: ATM phosphorylates TP53BP1 at DNA DSBs (Canis familiaris)


name: ATP(in) + H2O(in) + Zn(2+)(out) = ADP(in) + H(+)(in) + phosphate(in) + Zn(2+)(in)


name: DVL is ubiquitinated by CUL3:KLHL12:RBX1 (Rattus norvegicus)


name: EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG1 complex (Homo sapiens)


name: putrescine + S-adenosyl-L-methionine <=> H(+) + N-methylputrescine + S-adenosyl-L-homocysteine


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O => (9Z,12Z)-octadecadienoate + di-(9Z,12Z)-octadecadienoylglycerol + H(+)


name: PEX19:class I PMP binds PEX3 (Rattus norvegicus)


name: 1,2-dihexanoylglycerol + octadecanoyl-CoA = 1,2-dihexanoyl-3-octadecanoylglycerol + CoA


name: RFC dissociates after sliding clamp formation on the C-strand of the telomere (Bos taurus)


name: SLIT2-bound ROBO1 binds MYO9B (Mus musculus)


name: a jasmonate + an L-alpha-amino acid + ATP <=> a jasmonyl-L-amino acid + AMP + diphosphate + H(+)


name: a quinol + dihydroxyacetone phosphate => a quinone + sn-glycerol 3-phosphate


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Bos taurus)


name: EVL:PPL heterodimer binds the inner surface of the plasma membrane (Sus scrofa)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Homo sapiens)


name: Grb7 binds to the active PDGF receptor (Bos taurus)


name: acetyl-CoA + S-(2-aminoethyl)-L-cysteine => CoA + H(+) + S-(2-acetamidoethyl)-L-cysteine


name: a cis-alkene + CO2 => a cis-3-alkyl-4-alkyloxetan-2-one


name: acetyl-CoA + streptothricin F => CoA + H(+) + N(beta)-acetylstreptothricin F


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Caenorhabditis elegans)


name: Addition of nucleotides between position +11 and +30 (Schizosaccharomyces pombe)


name: (E)-phenylacetaldehyde oxime + O2 + reduced [NADPH--hemoprotein reductase] => (R)-mandelonitrile + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NNMT transfers CH3 from SAM to NAM to form MNA (Caenorhabditis elegans)


name: 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate => (S)-2-succinylamino-6-oxoheptanedioate + L-glutamate


name: Collagen type XXV ectomain shedding (Mus musculus)


name: COQ3 methylates DHDB (Caenorhabditis elegans)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Dictyostelium discoideum)


name: chloride(in) + dopamine(in) + Na(+)(in) => chloride(out) + dopamine(out) + Na(+)(out)


name: Expression of Interleukin-10 (Homo sapiens)


name: H2O + N(omega)-hydroxy-L-arginine + NAD(+) => H(+) + L-arginine + NADH + O2


name: p-4Y-PLCG1 dissociates from activated FGFR1 (Mus musculus)


name: PSMD11 binds PSMD7:PSMD12:PSMD13:PSMD14 (Drosophila melanogaster)


name: estrone + H(+) + NADPH => 17alpha-estradiol + NADP(+)


name: 2-oxoglutarate + L-histidinol phosphate <=> 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate


name: H(+) + meso-2,6-diaminoheptanedioate => CO2 + L-lysine


name: CGRP receptor can bind calcitonin gene-related peptides (Danio rerio)


name: IP receptor can bind prostacyclin (Bos taurus)


name: (4Z,15Z)-bilirubin IXalpha + NADP(+) = biliverdin IXalpha + H(+) + NADPH


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Gallus gallus)


name: beta-nicotinamide D-ribonucleotide + H2O <=> NH4(+) + nicotinate beta-D-ribonucleotide


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + choline = 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + ethanolamine


name: AMP + diphosphate + pristanoyl-CoA => 2,6,10,14-tetramethylpentadecanoate + ATP + CoA


name: The complex of HDAC1, RBL1 and E2F4 or HDAC1, RBL2, E2F4 or E2F5 binds E2F1 gene promoter (Homo sapiens)


name: a ribonucleoside 5'-triphosphate + AMP = a ribonucleoside 5'-diphosphate + ADP


name: ATP + H2O + lipid A-core(in) => ADP + H(+) + lipid A-core(out) + phosphate


name: KBTBD7:CUL3:RBX1 ubiquitinates NF1 (Dictyostelium discoideum)


name: (15Z)-tetracosenoate + taurine => H2O + N-(15Z-tetracosenoyl)-taurine


name: adenosylcob(III)yrate + 4 ADP + 4 H(+) + 4 L-glutamate + 4 phosphate => adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O + 4 L-glutamine


name: IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors (Danio rerio)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Plasmodium falciparum)


name: ABCA12 transports lipids from cytosol to extracellular region (Sus scrofa)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2 <=> 2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]acetate + H(+) + H2O2


name: 3,17-didehydrostemmadenine + H2O + NADPH => (16S)-deshydroxymethyl-stemmadenine + formate + NADP(+)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Caenorhabditis elegans)


name: Homodimerization  of DFF40 (Homo sapiens)


name: H(+)(in) + L-histidine(in) + L-ornithine(out) = H(+)(out) + L-histidine(out) + L-ornithine(in)


name: REST recruits the BHC complex (Bos taurus)


name: allocholate + deoxycholoyl-CoA => allocholoyl-CoA + deoxycholate


name: purine nucleotide transmembrane transporter activity


name: RHOB binds effectors at the plasma membrane (Xenopus tropicalis)


name: butyrolactone II + dimethylallyl diphosphate = butyrolactone I + diphosphate


name: MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Canis familiaris)


name: dGDP(out) + UTP(in) => dGDP(in) + UTP(out)


name: 2-oxoglutarate + chrodrimanin H + O2 => chrodrimanin E + CO2 + H2O + succinate


name: DHODH:FMN oxidises (S)-DHO to orotate (Drosophila melanogaster)


name: 2 2-iminio-3-(indol-3-yl)propanoate + H2O2 => chromopyrrolate + H(+) + 2 H2O + NH4(+)


name: 3-oxochola-1,4-dien-22-oate + H(+) + NADH + O2 => 9alpha-hydroxy-3-oxochola-1,4-dien-22-oate + H2O + NAD(+)


name: WIP binds WASP,N-WASP, activating them (Sus scrofa)


name: DDHD1,2 hydrolyse PA (Rattus norvegicus)


name: CREBBP, EP300 acetylates NFE2L2 (Canis familiaris)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Rattus norvegicus)


name: 2 O2 + 2 reduced [NADPH--hemoprotein reductase] + tirucalla-7,24-dien-3beta-ol => dihydroniloticin + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: hydroquinone O-beta-D-glucopyranoside(out) <=> hydroquinone O-beta-D-glucopyranoside(in)


name: 5-hydroxypentan-2-one + H(+) + NADH + NH4(+) => 5-hydroxypentan-2-amine + H2O + NAD(+)


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Schizosaccharomyces pombe)


name: 12,20-dihydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: FADH2 + H(+) + H2O + NADP(+) + rifampicin hemiaminal => FADH2-C4alpha-hydroperoxide + NADPH + rifampicin


name: Light stimulates opsin receptors (Xenopus tropicalis)


name: an [alpha-factor](in) + ATP + H2O <=> ADP + an [alpha-factor](out) + H(+) + phosphate


name: 2 H(+) + mevastatin + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pravastatin lactone


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Canis familiaris)


name: an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + H2O <=> 1-methyladenine + a 2'-deoxyribose 5'-phosphate in double-stranded DNA + H(+)


name: PKC autophosphorylates (Drosophila melanogaster)


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate


name: CoA + O-acetyl-L-threonyl-[protein] => acetyl-CoA + L-threonyl-[protein]


name: 4-chloro-L-threonyl-[peptidyl-carrier protein] + CO2 + H2O + succinate => 2-oxoglutarate + chloride + H(+) + L-threonyl-[peptidyl-carrier protein] + O2


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Sus scrofa)


name: acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-glucose <=> CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + H(+)


name: 2 H2O + indole-3-pyruvate imine dimer => 2 2-iminio-3-(indol-3-yl)propanoate + H2O2


name: 2-deoxy-D-glucose 6-phosphate + NADP(+) <=> 2-deoxy-6-phospho-D-glucono-1,5-lactone + H(+) + NADPH


name: 2-oxoglutarate + 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate => 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + L-glutamate


name: H2O + NAD(+) + prop-2-ynal <=> 2 H(+) + NADH + propynoate


name: H(+) + H2O + oxidized [electron-transfer flavoprotein] + trimethylamine = dimethylamine + formaldehyde + reduced [electron-transfer flavoprotein]


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + 8-methyladenosine(2503) in 23S rRNA + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: H(+) + hexacosanoyl-CoA + malonyl-CoA <=> 3-oxooctacosanyol-CoA + CO2 + CoA


name: Disassociation of Telomerase RNP and the Chromosome End (Rattus norvegicus)


name: N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine


name: Association of procollagen type XX (Rattus norvegicus)


name: 1-hexadecanoyl-2-(11Z,14Z,17Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol <=> (11Z,14Z,17Z-eicosatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: CS acetylates OA to citrate (Mus musculus)


name: A + H2O + spermidine <=> 4-aminobutanal + AH2 + propane-1,3-diamine


name: an N-acyl-sphingoid base + beta-D-Gal-(1->3)-beta-D-GalNAc-(1->3)-alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc => a globoside GalGb4Cer + H2O


name: nuatigenin + UDP-alpha-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose <=> a globoside NOR1 (d18:1(4E)) + H(+) + UDP


name: Luteinizing hormone receptor can bind LH (Sus scrofa)


name: Interaction of PECAM-1 and SHP-1 (Sus scrofa)


name: Degradation of ubiquitinated SMAD3 (Rattus norvegicus)


name: 1-O-alkyl-sn-glycero-3-phosphoethanolamine + H2O => 1-O-alkyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (9Z,11E,13E)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: GPVI stimulates PI3K beta, gamma (Homo sapiens)


name: Release of SMAC (DIABLO) from mitochondria (Rattus norvegicus)


name: all-trans-retinoate + UDP-alpha-D-glucuronate = all-trans-retinoyl-1-O-(beta-D-glucuronate) + UDP


name: a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: adenosylcob(III)inamide + apo-[corrinoid adenosyltransferase] + triphosphate => ATP + cob(I)inamide-[corrinoid adenosyltransferase]


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] => 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]


name: ADAMTS13 cleaves VWF multimer (Mus musculus)


name: [ThiI sulfur-carrier protein]-S-sulfanyl-L-cysteine + a uridine in tRNA + ATP + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> [ThiI sulfur-carrier protein]-L-cysteine + a 4-thiouridine in tRNA + AMP + diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: NEIL1 recognizes and binds FapyA-dsDNA (Homo sapiens)


name: PAOX:FAD oxidises NASPN to SPM (Mus musculus)


name: UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 (Xenopus tropicalis)


name: A + 2 H2O + N-acyl-15-methylhexadecasphing-4-enine => AH2 + N-acyl-15-methylhexadecasphinganine + O2


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Rattus norvegicus)


name: CDP-alpha-D-abequose + NADP(+) <=> CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H(+) + NADPH


name: ERK5 translocates to the nucleus (Mus musculus)


name: TRIM27 polyubiquitinates PTEN (Danio rerio)


name: Phosphorylated OPTN translocates to the nucleus (Sus scrofa)


name: Down Regulation of Emi1 through Phosphorylation of Emi1 (Sus scrofa)


name: Deamination at C6 position of adenosine in Editosome (ADAR2) (Caenorhabditis elegans)


name: H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH


name: 26S proteasome degrades Ub-NFE2L2 (Bos taurus)


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Gallus gallus)


name: aminobutyraldehyde dehydrogenase (NAD+) activity


name: Lactoferrin scavenges iron ions (Drosophila melanogaster)


name: very-long-chain 3-oxoacyl-CoA reductase activity


name: a fatty acid + NH4(+) => a fatty acylamide + H2O


name: D-mannonate + NAD(+) <=> H(+) + keto-D-fructuronate + NADH


name: MECP2 mutants R106W, D121G, R133H, S134F, T158M and T158A do not bind to 5mC-DNA (Homo sapiens)


name: Plasma membrane resorption (Homo sapiens)


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Sus scrofa)


name: Regulation of KIF23 (MKLP1) by phosphorylation (Rattus norvegicus)


name: PDP1 replaces VRI as binder to Clk and cry genes (Drosophila melanogaster)


name: myricetin + UDP-alpha-D-glucose <=> H(+) + myricetin 3-O-beta-D-glucoside + UDP


name: SLC29A1 transports RBV from extracellular region to cytosol (Caenorhabditis elegans)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Homo sapiens)


name: ATP + GTP => 2',3'-cGAMP + 2 diphosphate


name: PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Caenorhabditis elegans)


name: Caspase-mediated cleavage of vimentin at DSVD (85) (Canis familiaris)


name: DARC  is a non-specific receptor for many chemokines (Sus scrofa)


name: p-TARBP2 binds PKR (Drosophila melanogaster)


name: SU(VAR)2-10 binds to the phosphorylated STAT92E dimer and inhibits transcription (Drosophila melanogaster)


name: dehydroepiandrosterone 3-sulfate(out) <=> dehydroepiandrosterone 3-sulfate(in)


name: Sorafenib-resistant KIT mutants do not bind sorafenib (Homo sapiens)


name: campesterol + O2 + reduced [NADPH--hemoprotein reductase] = (22S)-22-hydroxycampesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DIMBOA beta-D-glucoside + H2O <=> D-glucose + DIMBOA


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Bos taurus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-octanoylsphinganine + O2 <=> 2 Fe(III)-[cytochrome b5] + H2O + N-octanoyl-4-hydroxysphinganine


name: Expression of TWINKLE (TWNK, PEO1) (Homo sapiens)


name: NOTCH1 gene transcription (Homo sapiens)


name: CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) => alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+)


name: GPI dimer isomerizes Fru(6)P to G6P (Canis familiaris)


name: FLIP(L) and procaspase-8 form heterodimer (Homo sapiens)


name: p-Y693-STAT4 dimerizes (Caenorhabditis elegans)


name: a long-chain fatty aldehyde + H2O + NAD(+) => a long-chain fatty acid + 2 H(+) + NADH


name: (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoate + O2 => (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-eicosatetraenoate


name: HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (Mus musculus)


name: coproporphyrin I(out) => coproporphyrin I(in)


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Bos taurus)


name: (R)-3-(indol-3-yl)lactoyl-CoA => (E)-3-(indol-3-yl)acryloyl-CoA + H2O


name: acetyl-CoA + succinyl-CoA => 3-oxoadipyl-CoA + CoA


name: HLA-A specific inhibitory MHC class I receptor activity


name: 7-chloroindole-3-pyruvate imine dimer <=> dichlorochromopyrrolate + H(+) + NH4(+)


name: S100A7 or S100A7A binds Zn2+ (Danio rerio)


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Bos taurus)


name: dimethylmaleate + H2O => (2R,3S)-2,3-dimethylmalate


name: 5-dehydro-6-demethoxy-6-hydroxyfumagillol + CO2 + succinate => 2-oxoglutarate + 5-dehydro-6-demethoxyfumagillol + O2


name: ACY1:Zn2+ dimer hydrolyses mercapturic acids (Mus musculus)


name: PalmS-ESRs bind CAVs (Rattus norvegicus)


name: ligase activity, forming carbon-nitrogen bonds


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Homo sapiens)


name: 1-deoxy-D-xylulose 5-phosphate + A + methanethiol => AH2 + S-methyl-1-thio-D-xylulose 5-phosphate


name: ABCA1 gene transcription regulated by NR1H2 or NR1H3 (Homo sapiens)


name: Electron transfer from ubiquinol to cytochrome c of complex III (Caenorhabditis elegans)


name: 2-oxoglutarate + heptyl sulfate + O2 <=> CO2 + H(+) + heptanal + succinate + sulfate


name: H2O + L-phenylalanocholate => cholate + L-phenylalanine


name: IL35 binds IL-12RB2:IL6ST receptor (Sus scrofa)


name: a primary methyl amine + H2O + O2 <=> an aldehyde + H2O2 + NH4(+)


name: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + oxidized dithiothreitol = 1,4-dithiothreitol + 2,3-epoxyphylloquinone


name: 1-(9Z-octadecenoyl)-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 9-hydroxy-octadecanoate


name: (S)-N-methylcoclaurine + O2 + reduced [NADPH--hemoprotein reductase] = (S)-3'-hydroxy-N-methylcoclaurine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: guanosine(out) + Na(+)(out) => guanosine(in) + Na(+)(in)


name: (3R)-hydroxy-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA => (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H2O


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Bos taurus)


name: Type II receptor phosphorylates type I receptor (Homo sapiens)


name: L-cysteine + L-histidine + O2 = H2O + L-alanin-3-yl L-histidin-5-yl sulfoxide


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Rattus norvegicus)


name: 4-hydroxybenzaldehyde + H2O + NADP(+) <=> 4-hydroxybenzoate + 2 H(+) + NADPH


name: SLC6A4 binds TCAs and SSRIs (Danio rerio)


name: B4GALT5/6 transfer Gal to GlcCer (Rattus norvegicus)


name: H(+) + NADH + UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate => NAD(+) + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Xenopus tropicalis)


name: G-protein alpha subunit is inactivated (Canis familiaris)


name: Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: asperterpenoid A + O2 + reduced [NADPH--hemoprotein reductase] = asperterpenoid C + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: glycerol + H(+) + octanoate => H2O + octanoylglycerol


name: GCHFR binds to GCH1 and negatively regulates its activity (Xenopus tropicalis)


name: SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Sus scrofa)


name: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose (Dictyostelium discoideum)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Canis familiaris)


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Bos taurus)


name: TST transfers sulfur from S2O3(2-) to HCN to form HSCN (Xenopus tropicalis)


name: PL(C)D4:3xCa2+ hydrolse PI(4,5)P2 to I(1,4,5)P3 and DAG at the ER membrane (Rattus norvegicus)


name: Binding of calnexin/calreticulin to the unfolded protein (Homo sapiens)


name: HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1 (Canis familiaris)


name: p-S295-PDE3B hydrolyses cAMP to AMP (Sus scrofa)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Bos taurus)


name: 4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = H(+) + isowyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine


name: WNT5A and WNT11 bind FZD receptors to initiate Ca2+ signaling (Homo sapiens)


name: a 3-oxo-Delta(4)-steroid => a 3-oxo-Delta(5)-steroid


name: (S)-benzoin + NADP(+) <=> benzil + H(+) + NADPH


name: 1,4-dodecanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => dodecan-1-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Rattus norvegicus)


name: 2,3-didehydroadipoyl-CoA + acetyl-CoA = 3-oxo-5,6-didehydrosuberyl-CoA + CoA


name: TBC1D10A (EPI64) binds ARF6:GTP (Sus scrofa)


name: D-maltoheptaono-1,5-lactone + H2O => D-maltoheptaonate + H(+)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Caenorhabditis elegans)


name: PKA phosphorylates PDE4B (Drosophila melanogaster)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Homo sapiens)


name: (5Z,8Z,11Z)-eicosatrienoate + O2 + reduced [NADPH--hemoprotein reductase] => 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Interaction of Tie2 and Dok-2 (Homo sapiens)


name: ALOX15 oxidises 17(S)-Hp-DHA to PDX (Danio rerio)


name: indole-3-carbonyl nitrile + O2 + reduced [NADPH--hemoprotein reductase] <=> 4-hydroxy-indole-3-carbonyl nitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-cystine = 2-aminoprop-2-enoate + S-sulfanyl-L-cysteine


name: a 2'-deoxyribonucleoside 5'-phosphate + a ribonucleoside => a 2'-deoxyribonucleoside + a ribonucleoside 5'-phosphate


name: 9-cis-retinol + tetradecanoyl-CoA => 9-cis-retinyl tetradecanoate + CoA


name: citrate(out) + trans-aconitate(in) <=> citrate(in) + trans-aconitate(out)


name: CASR binds CASR agonists (Canis familiaris)


name: H2O + P(1),P(2)-bis(5'-adenosyl) diphosphate <=> 2 AMP + 2 H(+)


name: PTK6 phosphorylates CDKN1B (Mus musculus)


name: NaS1 co-transports sulphate and a sodium ion (Rattus norvegicus)


name: 7-dehydrocholesterol + hnu => previtamin D3


name: adenosine 5'-phosphosulfate + ATP => 3'-phosphoadenylyl sulfate + ADP + H(+)


name: SUMO-CRABP2 binds atRA (Drosophila melanogaster)


name: Activated TP receptor binds G-proten Gq (Mus musculus)


name: PHLPP dephosphorylates S473 in AKT (Rattus norvegicus)


name: a fatty acyl-CoA + sphinganine => an N-acylsphinganine + CoA + H(+)


name: ABCA4 mediates atRAL transport (Canis familiaris)


name: LARG and PDZ-RhoGEF binds to Plexin-B1 (Homo sapiens)


name: FOXO4:ATXN3 binds SOD2 gene promoter (Homo sapiens)


name: sequestered tissue factor -> tissue factor (Gallus gallus)


name: 3-oxosphinganine + eicosanoyl-CoA => CoA + H(+) + N-eicosanoyl-3-oxosphinganine


name: NTPDase4 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)


name: NPL cleaves Neu5Ac,Neu5Gc to ManNAc,ManNGc and pyruvate (Sus scrofa)


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Mus musculus)


name: Formation of Okazaki fragments (Canis familiaris)


name: 2 H(+) + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin]


name: 8-hydroxysalvigenin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] + salvigenin


name: PDGF binds to extracellular matrix proteins (Rattus norvegicus)


name: an S-substituted L-cysteinylglycine + H2O = an S-substituted L-cysteine + glycine


name: Activated TAK1 leaves endosome membrane (Gallus gallus)


name: Kinesin-5 is a homotetramer (Gallus gallus)


name: ORC6 binds KPNA1 or KPNA6 (Schizosaccharomyces pombe)


name: 1,4-benzoquinone + H(+) + NADH => hydroquinone + NAD(+)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Rattus norvegicus)


name: ACER2 hydrolyzes ceramide (Golgi) (Rattus norvegicus)


name: HDAC6 deacetylates microtubules (Sus scrofa)


name: Recruitment of GADS:SLP-76 to p-5Y-LAT (Homo sapiens)


name: SUMOylation of TDG with SUMO2,3 (Xenopus tropicalis)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: beta-alanyl-L-lysine + H2O = beta-alanine + L-lysine


name: ADAM10:Zn2+:TSPANs translocates from ER lumen to plasma membrane (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + sungeidine F => adenosine 3',5'-bisphosphate + H(+) + sulfosungeidine F


name: all-trans-undecaprenol + ATP = ADP + all-trans-undecaprenyl phosphate + H(+)


name: E2F1 binds the FBXO5 gene promoter (Homo sapiens)


name: Activation of GIRK/Kir3 Channels (Bos taurus)


name: decanoyl-CoA + phytol = CoA + decanoate phytyl ester


name: 2-methoxy-6-all-trans-decaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine <=> 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: Membrane estrogen receptors bind SRC (Rattus norvegicus)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Rattus norvegicus)


name: (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O => (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione


name: RAC3 GDIs block activation of RAC3 (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol <=> a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: benzylamine + H2O + O2 => benzaldehyde + H2O2 + NH4(+)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Bos taurus)


name: Dissociation of Phospho-Nlp from the centrosome (Mus musculus)


name: mycinamicin VI + S-adenosyl-L-methionine => H(+) + mycinamicin III + S-adenosyl-L-homocysteine


name: 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate => 19-(4-hydroxyphenyl)nonadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase]


name: ERBB4 ubiquitination by WWP1/ITCH (Sus scrofa)


name: AUF1 (hnRNP D0) is ubiquitinylated (Plasmodium falciparum)


name: ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine (Xenopus tropicalis)


name: (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + H(+) + O2 <=> 3-[(Z)-2-isocyanoethenyl]-1H-indole + 2 CO2 + H2O + succinate


name: Translocation of PDGF from ER to Golgi (Homo sapiens)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Rattus norvegicus)


name: 2-acyl LPG is acylated to PG by LPGAT (Sus scrofa)


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Bos taurus)


name: FUNDC1 is phosphorylated by CK2 (Mus musculus)


name: (R)-carnitine(out) + Na(+)(out) => (R)-carnitine(in) + Na(+)(in)


name: ERBB4s80 binds the APOE gene (Homo sapiens)


name: (9Z,11E)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (11E)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: (8Z,11Z,14Z)-heptadecatrienal + A + H2O = (8Z,11Z,14Z)-heptadecatrienoate + AH2 + H(+)


name: IL37(?-218) translocates from the cytosol to the nucleus (Danio rerio)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Xenopus tropicalis)


name: MEOS oxidizes ethanol to acetaldehyde (Drosophila melanogaster)


name: Association of beta-catenin with the destruction complex (Drosophila melanogaster)


name: H(+) + menaquinone-8 + NADPH <=> menaquinol-8 + NADP(+)


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine = 1-hexadecanoyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Drosophila melanogaster)


name: an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O = an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + D-galactosamine


name: Activation of proMMP11 by FURIN (Drosophila melanogaster)


name: CoA + glycocholate + H(+) => choloyl-CoA + glycine


name: phosphorylation of IRAK2 by activated IRAK4  (Gallus gallus)


name: ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Rattus norvegicus)


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Canis familiaris)


name: H2O + L-aspartate + O2 => H2O2 + NH4(+) + oxaloacetate


name: Cis-homodimerization of nectins (Xenopus tropicalis)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Saccharomyces cerevisiae)


name: HSF1 trimer translocates to the nucleus (Bos taurus)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Schizosaccharomyces pombe)


name: 6-azauridine + ATP <=> 6-azauridine 5'-phosphate + ADP + H(+)


name: (2R,3S,4S)-leucocyanidin + 2-oxoglutarate + O2 => (4S)-2,3-dehydroleucocyanidin + CO2 + H(+) + H2O + succinate


name: TFIIH-class transcription factor complex binding


name: H(+) + imidazole-4-acetate + NADH + O2 => 5-hydroxyimidazole-4-acetate + H2O + NAD(+)


name: cAMP activates EPAC2 (Schizosaccharomyces pombe)


name: E2F1 binds the TK1 gene promoter (Homo sapiens)


name: 1,2-dioctadecanoyl-sn-glycero-3-phosphate + H2O => 1,2-dioctadecanoyl-sn-glycerol + phosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CMP-N-acetyl-beta-neuraminate + ganglioside GT1a alpha => CMP + ganglioside GQ1b alpha + H(+)


name: Formation of a heteromeric BMP receptor complex (Sus scrofa)


name: O2 + octadecanoate <=> (2R)-2-hydroperoxyoctadecanoate


name: OGDH dimer decarboxylates 2-OG (Dictyostelium discoideum)


name: p130 (RBL2) associates with MuvB to form DREAM complex (Drosophila melanogaster)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Mus musculus)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: SGTA binds Tail-anchored protein (Dictyostelium discoideum)


name: EPHB:NMDAR binds TIAM1 (Rattus norvegicus)


name: cyanidin + UDP-alpha-D-glucose <=> cyanidin 3-O-beta-D-glucoside + H(+) + UDP


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-sn-glycero-3-phosphocholine <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: IL1F10(?-152) binds IL1RAPL1 (Mus musculus)


name: ENPP7 hydrolyzes sphingomyelin (Homo sapiens)


name: DCP1-DCP2 complex decaps mRNA (Rattus norvegicus)


name: Ligation of DNA and formation of Holliday structures following repair synthesis (Gallus gallus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + homogentisate => 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate


name: a fatty acid + H(+) + sn-glycero-3-phospho-L-serine => a 1-acyl-sn-glycero-3-phospho-L-serine + H2O


name: alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose = alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+)


name: p75NTR interacts with RIP2 (Danio rerio)


name: (+)-sesamin dicatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) => (+)-sesamin monocatechol + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n)


name: JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Canis familiaris)


name: MT-MMPs are sorted to the plasma membrane (Drosophila melanogaster)


name: Sema3A binds Nrp-1 bound to PlexinA (Drosophila melanogaster)


name: (2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O + L-glutamate


name: Removal of RNA primer and dissociation of RPA and Dna2 from the C-strand (Canis familiaris)


name: Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Mus musculus)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)


name: (1S,2R)-ephedrine + NAD(+) <=> (R)-2-methylamino-1-phenylpropan-1-one + H(+) + NADH


name: L-methionine = 2-aminobut-2-enoate + methanethiol


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)


name: Phosphorylated KHDRBS1 translocates to the cytosol (Sus scrofa)


name: ZnT8 transports zinc into the Golgi apparatus (Sus scrofa)


name: Co-precorrin-8X + H(+) + S-adenosyl-L-homocysteine => Co-precorrin-7 + S-adenosyl-L-methionine


name: Vesicular inhibitory amino acid transport (Saccharomyces cerevisiae)


name: GRB2-1:SOS1 binds p-Y-SHC (Canis familiaris)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Mus musculus)


name: H2O + O2 + spermine = 3-aminopropanal + H2O2 + spermidine


name: dihydromonacolin L carboxylate + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + monacolin L carboxylate + oxidized [NADPH--hemoprotein reductase]


name: DDX5 binds ESR1:estrogen:TFF1 gene promoter (Bos taurus)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Homo sapiens)


name: an (S)-2-haloacid + H2O <=> a (2R)-2-hydroxycarboxylate + a halide anion + H(+)


name: (2E,6E)-farnesyl diphosphate <=> beta-bisabolene + diphosphate


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Sus scrofa)


name: ATP binds G-protein beta associated TRiC/CCT (Drosophila melanogaster)


name: p25-bound CDK5 phosphorylates CDC25C (Homo sapiens)


name: Furin cleaves pro-protein S to protein S (Bos taurus)


name: SUMOylation of NFKB2 with SUMO1 (Sus scrofa)


name: ent-copalyl diphosphate = diphosphate + ent-pimara-9(11),15-diene


name: 2-hydroxymethyl-3-pentylphenol + O2 + reduced [NADPH--hemoprotein reductase] => (8S)-annullatin E + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Canis familiaris)


name: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine <=> an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine


name: KHK dimer phosphorylates Fru to Fru 1-P (Homo sapiens)


name: 2-oxoglutarate + dodecyl sulfate + O2 <=> CO2 + dodecanal + H(+) + succinate + sulfate


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Drosophila melanogaster)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Mus musculus)


name: Activation of NIK (Saccharomyces cerevisiae)


name: AMP + D-ribose 5-phosphate + 2 H(+) => ADP-D-ribose + H2O


name: Microtubule-independent trafficking of connexons to the plasma membrane (Canis familiaris)


name: 2-oxoglutarate + L-isoleucine + O2 => (4S)-4-hydroxy-L-isoleucine + CO2 + succinate


name: (14R,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (12S)-hydroperoxy-(14R,15S)-epoxy-(5Z,8Z,10E)-eicosatrienoate


name: phycourobilin-L-cysteinyl(84)-[R-phycocyanin alpha-subunit] => (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(84)-[R-phycocyanin alpha-subunit]


name: (2S)-2-hydroxyheptanenitrile => hexanal + hydrogen cyanide


name: dodecanoyl-CoA + H(+) + L-serine <=> 3-oxotetradecasphinganine + CO2 + CoA


name: FITM1, FITM2 bind TAGs (Canis familiaris)


name: TLR9 processing at neutral pH (Sus scrofa)


name: factor XIIa binds SERPING1 (Homo sapiens)


name: NOTCH1 PEST domain mutants bind JAG1 (Homo sapiens)


name: 1D-myo-inositol 2,3-bisphosphate + phosphate => 1D-myo-inositol 1,2,3-trisphosphate + H2O


name: mechanosensitive potassium channel activity


name: PDSS1,2 ligates FPP to IPPP (Schizosaccharomyces pombe)


name: Fc gamma receptors interact with antigen-bound IgG (Homo sapiens)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Bos taurus)


name: p-GFAP:GFAP dissociates from LAMP2a multimer (Homo sapiens)


name: PDE4A binds PDE4A inhibitors (Canis familiaris)


name: 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H(+)


name: 6-decylubiquinone + 2 thiosulfate => 6-decylubiquinol + tetrathionate


name: BAD displaces tBID from BCL-2 sequestration (Canis familiaris)


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Sus scrofa)


name: 2 Na(+)(out) + taurolithocholate 3-sulfate(out) = 2 Na(+)(in) + taurolithocholate 3-sulfate(in)


name: H2O + L-alanine + NAD(+) <=> H(+) + NADH + NH4(+) + pyruvate


name: Hikeshi binds HSP70s:ATP (Saccharomyces cerevisiae)


name: nicotinamide + nicotinate-adenine dinucleotide phosphate => NADP(+) + nicotinate


name: 2-hydroxyethane-1-sulfonate + FMNH2 + O2 = FMN + glycolaldehyde + 2 H(+) + H2O + sulfite


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Rattus norvegicus)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Canis familiaris)


name: futalosine => chorismate + inosine + phosphoenolpyruvate


name: Aquaporins passively transport glycerol into cells (Sus scrofa)


name: cocaine + H2O = benzoate + ecgonine methyl ester + H(+)


name: INTL1 binds bacterial glycans (Xenopus tropicalis)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Danio rerio)


name: N(5)-alkyl-L-glutaminyl-[protein] + NH4(+) => an alkylamine + L-glutaminyl-[protein]


name: 16beta,17beta-estriol + UDP-alpha-D-glucuronate = 16beta,17beta-estriol 16-O-(beta-D-glucuronate) + H(+) + UDP


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Caenorhabditis elegans)


name: Transport of antigen loaded MHC II molecules to surface (Sus scrofa)


name: PRMT1,PRMT6 methylate arginine-4 of histone H4 (Plasmodium falciparum)


name: acetyl-CoA + L-lysyl-[alpha-tubulin] => CoA + H(+) + N(6)-acetyl-L-lysyl-[alpha-tubulin]


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)


name: A + decanedioyl-CoA => (2E)-decenedioyl-CoA + AH2


name: N-[omega-(9Z,12Z)-octadecadienoyloxy]-acylsphin-4-enine + O2 => N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine


name: Dopamine translocates to a secretory vesicle (Homo sapiens)


name: Defective MMADHC does not bind MMACHC:B12r (Homo sapiens)


name: L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] <=> H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)


name: cAMP dissociates PKA, promoting GLI processing (Gallus gallus)


name: Histone acetyltransferases are recruited to the TFF1 gene (Xenopus tropicalis)


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Rattus norvegicus)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Homo sapiens)


name: SARS-CoV-2 nsp16 binds to U1 snRNA (Homo sapiens)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine


name: diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + H(+) + S-adenosyl-L-homocysteine => C30 botryococcene + S-adenosyl-L-methionine


name: (S)-2,3-diaminopropanoate + ATP + fumarate = AMP + diphosphate + N(3)-fumaroyl-(S)-2,3-diaminopropanoate


name: (2E,6E)-farnesal + H2O + NAD(+) <=> (2E,6E)-farnesoate + 2 H(+) + NADH


name: L-gulonate + NADP(+) => aldehydo-D-glucuronate + H(+) + NADPH


name: a 2'-deoxyguanosine in DNA + glyoxal <=> an N(2)-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA


name: (25R)-cholest-5-ene-3beta,26-diol + O2 + reduced [NADPH--hemoprotein reductase] <=> (25R)-cholest-5-en-3beta,7alpha,26-triol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: tBID activates BAX protein (Danio rerio)


name: a menaquinol + NAD(+) => a menaquinone + H(+) + NADH


name: alpha-D-glucosamine 6-phosphate + H2O <=> beta-D-fructose 6-phosphate + NH4(+)


name: Phosphorylation of TEC kinases by p-SYK (Mus musculus)


name: D-serine + NADP(+) <=> 2-aminomalonate semialdehyde + H(+) + NADPH


name: (1R,3R)-chrysanthemate + 2 H(+) + NADPH => (1R,3R)-chrysanthemal + H2O + NADP(+)


name: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol (Sus scrofa)


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Xenopus tropicalis)


name: 2-naphthyl sulfate + phenol = 2-naphthol + phenyl sulfate


name: CoA + H(+) + olivetolate => 3,5,7-trioxododecanoyl-CoA


name: 4-methoxyestrone + UDP-alpha-D-glucuronate = 4-methoxyestrone 3-O-(beta-D-glucuronate) + H(+) + UDP


name: doxorubicin + H2O + NADP(+) => daunorubicin + H(+) + NADPH + O2


name: (2-acetamidoethyl)phosphonate + CoA + H(+) => (2-aminoethyl)phosphonate + acetyl-CoA


name: 2',3'-cyclophospho-AMP + H2O <=> adenosine 2'-phosphate + H(+)


name: (R)-benzodiazepinedione + dimethylallyl diphosphate <=> (2S,3R,11R)-aszonalenin + diphosphate


name: CO2 + N(2)-succinyl-L-ornithine + 2 NH4(+) => 2 H(+) + 2 H2O + N(2)-succinyl-L-arginine


name: glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Canis familiaris)


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Bos taurus)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Saccharomyces cerevisiae)


name: SFKs phosphorylate VAV2,3 (Canis familiaris)


name: SPRY2 binds GRB2 (Drosophila melanogaster)


name: ATP + CoA + octanedioate => AMP + diphosphate + octanedioyl-CoA


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Dictyostelium discoideum)


name: Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 (Mus musculus)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Canis familiaris)


name: Fibrillin-1 binds latent TGF-beta (Bos taurus)


name: Caspase mediated cleavage of beta-catenin (Xenopus tropicalis)


name: 2-oxoglutarate + 6-sulfo-D-quinovose + O2 = 6-dehydro-D-glucose + CO2 + H(+) + succinate + sulfite


name: cholesterol + 6 H(+) + 3 O2 + 6 reduced [adrenodoxin] <=> 4-methylpentanal + 4 H2O + 6 oxidized [adrenodoxin] + pregnenolone


name: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+)


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Rattus norvegicus)


name: beta-acoradiene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate


name: 8-hydroxy-7-methoxyflavone + S-adenosyl-L-methionine = 7,8-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Canis familiaris)


name: acetate + spermidine => H2O + N(1)-acetylspermidine


name: PKA phosphorylates NOS3 (eNOS) on serine-633 (Gallus gallus)


name: Interaction of PECAM-1 and PLC gamma1 (Sus scrofa)


name: CTNNB1 dissociates from CDH11 upon ANGPTL4 binding (Xenopus tropicalis)


name: Insertion of correct bases opposite the lesion by POLH (Schizosaccharomyces pombe)


name: HS2ST1 sulfates IdoA at C2 in heparan sulfate (Danio rerio)


name: Defective MTR does not transfer CH3 group from MeCbl to HCYS (Homo sapiens)


name: Gamma-carboxy pro-factor VII transport from the endoplasmic reticulum to the Golgi apparatus (Danio rerio)


name: ERBB4 ubiquitination by WWP1/ITCH (Caenorhabditis elegans)


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + nonanoate => 1-octadecanoyl-2-nonanoyl-sn-glycero-3-phosphocholine + H2O


name: Ub,pS335,S338,T NFE2L2 is degraded (Mus musculus)


name: USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Sus scrofa)


name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA (Homo sapiens)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Mus musculus)


name: Growth hormone receptor binds JAK2 (Danio rerio)


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Homo sapiens)


name: UDP-alpha-D-glucuronate + zolasartan = UDP + zolarsartan-2-N-beta-D-glucuronide


name: CUBN binds GC:25(OH)D (Rattus norvegicus)


name: 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + a mycolipenoyl-CoA = 2-O-(long-chain fatty acyl)-3-O-mycolipenoyl-trehalose + CoA


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-L-serine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + H2O


name: NOTCH3-ligand complex is cleaved to produce NEXT3 (Gallus gallus)


name: GTP + L-histidyl-[RNA ligase] = diphosphate + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase]


name: 3-deacetyl-3-vinylbacteriochlorophyllide a + ADP + 2 oxidized [2Fe-2S]-[ferredoxin] + phosphate <=> ATP + chlorophyllide a + H(+) + H2O + 2 reduced [2Fe-2S]-[ferredoxin]


name: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate <=> cyclic pyranopterin phosphate + diphosphate


name: a 3'-end uridylyl-2',3'-cyclophospho-uridine-RNA + a 5'-end dephospho-ribonucleoside-RNA => uridylyl-uridylyl-ribonucleotide-RNA


name: corticosterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] = 18-hydroxycorticosterone + H2O + 2 oxidized [adrenodoxin]


name: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine => 3-((4-bromophenyl)sulfanyl)-2-oxopropanoate + L-glutamate


name: RND1 binds effectors (Saccharomyces cerevisiae)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Bos taurus)


name: Ribosomal scanning  (Plasmodium falciparum)


name: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) => 2-aminomuconate 6-semialdehyde + CO2


name: 2 H2O + iminodiacetonitrile => N-(cyanomethyl)glycine + NH4(+)


name: pppA(2'-5')pG <=> 3',2'-cGAMP + diphosphate


name: BDNF-bound NTRK2 dimerizes (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho]-glycerol + CoA


name: Association of procollagen type I (Mus musculus)


name: CYP3A4 monooxygenates ATVL to 4-OH-ATVL (Canis familiaris)


name: DCN (decorin) degradation by MMP14 (Sus scrofa)


name: 5-taurinomethyluridine(34) in tRNA + AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] = 5-taurinomethyl-2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]


name: 3,4-dihydroxyphenylacetaldehyde + H2O + NAD(+) => 3,4-dihydroxyphenylacetate + 2 H(+) + NADH


name: p-Y705-STAT3,p-Y641-STAT6 dissociate (Mus musculus)


name: acetyl-CoA + 9 H(+) + holo-[ACP] + 9 malonyl-CoA => 3-(2,4-dioxopentyl)-3,6,8,9-tetrahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] + 9 CO2 + 10 CoA + 2 H2O


name: diphosphate + H(+) + N(epsilon)-GMP-L-lysyl-[protein] => GTP + L-lysyl-[protein]


name: GIP receptor binds gastric inhibitory peptide (Xenopus tropicalis)


name: 2-exo-hydroxy-1,4-cineole + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 1,4-cineole + O2 + reduced [NADPH--hemoprotein reductase]


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Caenorhabditis elegans)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Sus scrofa)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> diphosphate + neoverrucosan-5beta-ol


name: p-PIK3AP1 (p-BCAP) binds PIK3CD:PIK3R1 (PI3K delta) (Homo sapiens)


name: Cleavage of Procaspase-7 by the apoptosome (Canis familiaris)


name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Rattus norvegicus)


name: an N(1)-methylpseudouridine in rRNA + H(+) + S-adenosyl-L-homocysteine => a pseudouridine in rRNA + S-adenosyl-L-methionine


name: (R)-carnitine(out) + O-acyl-(R)-carnitine(in) => (R)-carnitine(in) + O-acyl-(R)-carnitine(out)


name: H2O + pentanoyl-CoA => CoA + H(+) + pentanoate


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Dictyostelium discoideum)


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Drosophila melanogaster)


name: indoxyl + UDP-alpha-D-glucose => H(+) + indican + UDP


name: steviol + UDP-alpha-D-glucose = H(+) + steviolmonoside + UDP


name: USP30 binds ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: (2E)-geranyl diphosphate => (-)-car-3-ene + diphosphate


name: Uncoating of SARS-CoV-2 Genome (Homo sapiens)


name: (4R)-hydroxysphinganine + 2-hydroxyhexacosanoyl-CoA => CoA + H(+) + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: 1-O-(1Z)-hexadecenyl-2 (5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + H(+)


name: a ganglioside GA2 + H2O <=> a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-acetyl-beta-D-galactosamine


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: (9Z)-pentadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (9Z,12Z)-pentadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Syk activation leads to SLP-76 activation (Mus musculus)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Schizosaccharomyces pombe)


name: 6-kestotriose + sucrose = 6,6-kestotetraose + beta-D-glucose


name: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoylglycerol <=> 1-octadecanoyl-3-(9Z-octadecenoyl)-glycerol + CoA


name: a 5'-end 5'-phospho-ribonucleoside-RNA + S-adenosyl-L-methionine = a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine


name: 2,4-dinitroanisole + H2O = 2,4-dinitrophenol + H(+) + methanol


name: CDH11 forms homotypic trans dimer (Homo sapiens)


name: D-allo-threonine + H2O + O2 <=> (R)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Saccharomyces cerevisiae)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H(+)


name: HS3ST1 sulfates GlcN at C3 in heparan sulfate (Caenorhabditis elegans)


name: S-methyl-5-thio-D-ribulose 1-phosphate = 2-(methylsulfanyl)acetaldehyde + dihydroxyacetone phosphate


name: Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins (Homo sapiens)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O => (9Z)-octadecenoate + 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Sus scrofa)


name: RUNX3 translocates to the nucleus (Sus scrofa)


name: A + D-glucose <=> AH2 + D-glucono-1,5-lactone


name: Activation of Rac1 by VAV2 (Drosophila melanogaster)


name: Removal of miRNA passenger strand (Homo sapiens)


name: Anti-MET small tyrosine kinase inhibitors bind MET (Sus scrofa)


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Homo sapiens)


name: Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Rattus norvegicus)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Homo sapiens)


name: DOLK phosphorylates DCHOL to DOLP (Homo sapiens)


name: NFE2L2 binds KEAP1:NEDD8-CUL3:RBX1 (Homo sapiens)


name: IkB is ubiquitinated and degraded (Sus scrofa)


name: fluoroacetyl-CoA + H2O <=> CoA + fluoroacetate + H(+)


name: SLC16A10-mediated uptake of aromatic amino acids (Homo sapiens)


name: "With NADH or NADPH as one donor, and the other dehydrogenated"


name: ATP + 2 N-(3-carboxypropanoyl)-N-hydroxycadaverine <=> AMP + bisucaberin B + diphosphate + H(+)


name: NAB2 and CHD4 bind and repress EGR-mediated RRAD gene expression (Rattus norvegicus)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Sus scrofa)


name: CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Danio rerio)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Mus musculus)


name: KIT binds type II TKIs (Xenopus tropicalis)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Canis familiaris)


name: dGTP + 2 H2O = dGMP + 2 H(+) + 2 phosphate


name: RHOC activates endoplasmic reticulum effectors (Homo sapiens)


name: Alternative endo-mannosidase I route (Xenopus tropicalis)


name: PTK6 phosphorylates KHDRBS2 (Sus scrofa)


name: a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine


name: AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Canis familiaris)


name: 4-methyl-2-oxopentanoate(out) + H(+)(out) <=> 4-methyl-2-oxopentanoate(in) + H(+)(in)


name: UDP-alpha-D-glucose + vancomycin aglycone = devancoaminyl-vancomycin + UDP


name: 4-amino-5-aminomethyl-2-methylpyrimidine + H2O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)


name: Phosphorylation of STATs (Canis familiaris)


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Homo sapiens)


name: p62 is recruited and forms a complex with TRAF6 (Homo sapiens)


name: 5,6-dihydroxyindole + CO2 => D-dopachrome + H(+)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Bos taurus)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Canis familiaris)


name: SPTLC complexes transfer acyl-CoA onto serine (Mus musculus)


name: Phosphorylation of MEK4 by MEKK1 (Dictyostelium discoideum)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Plasmodium falciparum)


name: D-tryptophan + tRNA(Trp) => D-tryptophanyl-tRNA(Trp) + H2O


name: ATP + citrate + D-ornithine = AMP + diphosphate + H(+) + N(5)-[(S)-citryl]-D-ornithine


name: 2-oxoglutarate + 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate = 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + L-glutamate


name: (S)-lactaldehyde + H2O + NAD(+) => (S)-lactate + 2 H(+) + NADH


name: CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D (Sus scrofa)


name: (Z)-2-methylureidoacrylate + H2O = (Z)-2-methylaminoacrylate + carbamate + H(+)


name: cholesterol + O2 = cholest-5-en-3-one + H2O2


name: Phosphorylation of TSC2 by PKB (Sus scrofa)


name: 4-methylpentan-1-ol + NADP(+) <=> 4-methylpentanal + H(+) + NADPH


name: eNOS:NOSIP translocation from caveolae to intracellular compartments (Homo sapiens)


name: (3R)-hydroxy-beta-ionone + all-trans-10'-apo-beta-carotenal => beta-cryptoxanthin + O2


name: a 5-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine => a cytidine in rRNA + S-adenosyl-L-methionine


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase]


name: The keratan chain can be capped by N-acetylneuraminic acid (Canis familiaris)


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O => beta-D-glucose + N-hexadecanoylsphing-4-enine


name: KIT binds type II TKIs (Rattus norvegicus)


name: N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine <=> H(+) + N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H2O


name: SLC5A8 transports monocarboxylates from extracellular region to cytosol (Canis familiaris)


name: deoxyadlupulone + dimethylallyl diphosphate => adlupulone + diphosphate + H(+)


name: Formation of the PA28-alpha-beta regulatory particle (Mus musculus)


name: 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Sus scrofa)


name: L-idonate + NAD(+) <=> 2-dehydro-L-idonate + H(+) + NADH


name: biliverdin IXalpha + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => (3Z)-phytochromobilin + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ATP + D-glucose <=> ADP + D-glucose 6-phosphate + H(+)


name: PIK3C3:PIK3R4 phosphorylates PI to PI3P (Gallus gallus)


name: 2-oxoglutarate + a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + H2O + O2 <=> a 2'-deoxycytidine in double-stranded DNA + CO2 + glyoxal + succinate


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Danio rerio)


name: 4-hydroxy-2-oxoglutarate => glyoxylate + pyruvate


name: 4-formylbenzenesulfonate + H2O + NAD(+) <=> 4-sulfobenzoate + 2 H(+) + NADH


name: Active ALK binds SHC1 (Rattus norvegicus)


name: LTD4 is converted to LTE4 by DPEP1/2 (Rattus norvegicus)


name: (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + H2O = (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H(+)


name: 2-oxoadipate + L-kynurenine = H2O + kynurenate + L-2-aminoadipate


name: SOS1-mediated nucleotide exchange of RAS downstream of FLT3 (Bos taurus)


name: L-glutamine(in) + L-serine(out) + Na(+)(in) => L-glutamine(out) + L-serine(in) + Na(+)(out)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 <=> 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O


name: (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> (7S,17S)-dihydroperoxy-(4Z,8E,10Z,13Z,15E,19Z)-docosahexaenoate


name: CO2 + 3 H2O + pentadecanal => H(+) + 2 H2O2 + hexadecanoate


name: ent-copalyl diphosphate <=> diphosphate + ent-cassa-12,15-diene


name: ALOX5 oxidises DHA to 7-HDHA (Xenopus tropicalis)


name: AMP(out) + FAD(in) => AMP(in) + FAD(out)


name: Phosphorylation (Ser5) of RNA pol II CTD (Drosophila melanogaster)


name: bergapten + S-adenosyl-L-homocysteine => bergaptol + S-adenosyl-L-methionine


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O => 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)


name: Sprouty lures CBL away from EGFR (Sus scrofa)


name: BGN binds Collagen types I, VI, (IX) (Danio rerio)


name: ATP + L-isoleucine + tRNA(Ile) <=> AMP + diphosphate + L-isoleucyl-tRNA(Ile)


name: (25R)-cholest-5-ene-3beta,26-diol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (25R)-3beta-hydroxy-5-cholesten-26-al + 2 H2O + 2 oxidized [adrenodoxin]


name: 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 <=> 7-chloroindole-3-pyruvate imine dimer + 2 H2O


name: H(+) + NADH + O2 + p-cumate = (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Schizosaccharomyces pombe)


name: diphosphate + sesquisabinene B => (2E,6E)-farnesyl diphosphate


name: dihydroxyacetone phosphate + H2O => dihydroxyacetone + phosphate


name: RNF181 polyubiquinates BCL10 (Bos taurus)


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)


name: ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Sus scrofa)


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine


name: CBCAP complex binds 7-methylguanosine cap of snRNA (Homo sapiens)


name: eicosanoyl-CoA + H(+) + malonyl-CoA <=> 3-oxodocosanoyl-CoA + CO2 + CoA


name: IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Sus scrofa)


name: bHEXA,bHEXB hydrolyze PSAP(195-273):Gb4Cer:PE (Drosophila melanogaster)


name: Uncoupled eNOS favours the formation of superoxide (Sus scrofa)


name: (2'R)-atrovenetin + S-adenosyl-L-methionine = deoxyherqueinone + H(+) + S-adenosyl-L-homocysteine


name: 1,2-dioctanoyl-3-O-beta-D-galactosyl-sn-glycerol + H2O => 2-octanoyl-3-O-beta-D-galactosyl-sn-glycerol + H(+) + octanoate


name: dTDP-N-hydroxy-beta-L-evernosamine + H(+) + NADPH + O2 => dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 H2O + NADP(+)


name: CBLIF binds RCbl (Drosophila melanogaster)


name: Caspase-mediated cleavage of Acinus (Homo sapiens)


name: CatSper Channel Mediated Calcium Transport (Sus scrofa)


name: Activated Phospholipase C beta-1 hydrolyzes 1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate (Rattus norvegicus)


name: 3-dehydroshikimate + H(+) + NADPH => NADP(+) + shikimate


name: ATP + gamma-L-glutamyl-L-cysteine + glycine <=> ADP + glutathione + H(+) + phosphate


name: GMPS dimer transforms 6TXMP to 6TGMP (Xenopus tropicalis)


name: (2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 6-phosphate = (2R)-3-phosphoglycerate + alpha-D-glucose 1,6-bisphosphate + H(+)


name: SLC5A2 binds gliflozins (Canis familiaris)


name: S-adenosyl-L-methionine + uridine(2634) in 25S rRNA = H(+) + N(3)-methyluridine(2634) in 25S rRNA + S-adenosyl-L-homocysteine


name: (R)-glycerate + GDP-alpha-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + GDP + H(+)


name: Cleavage of Procaspase-3 by the apoptosome (Bos taurus)


name: Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane (Homo sapiens)


name: JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Bos taurus)


name: Formation of MSH1:PMS2 Complex (Canis familiaris)


name: ITCH binds DTX (Drosophila melanogaster)


name: Multiubiquitination of Nek2A (Canis familiaris)


name: 3-dehydro-L-gulonate + H(+) = CO2 + L-xylulose


name: 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + NH4(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + H2O


name: 1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) + octanoate


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Xenopus tropicalis)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Drosophila melanogaster)


name: 17beta-hydroxyestr-4-en-3-one + H(+) + NADPH <=> 17beta-hydroxy-5beta-estran-3-one + NADP(+)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Rattus norvegicus)


name: ubiquitin-protein transferase inhibitor activity


name: benzoyl-CoA + hexan-2-ol = CoA + hexan-2-yl benzoate


name: acetyl-CoA + dodecanedioyl-CoA => 3-oxotetradecanedioyl-CoA + CoA


name: 2',4,4',6'-tetrahydroxychalcone 4'-O-beta-D-glucoside + O2 <=> aureusidin 6-O-beta-glucoside + H2O


name: KDSR reduces 3-ketosphingoid (Bos taurus)


name: H2O + L-ectoine => (2S)-2-acetamido-4-aminobutanoate


name: GLYCTK phosphorylates DGA to 3PDGA (Homo sapiens)


name: lochnericine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + horhammericine + oxidized [NADPH--hemoprotein reductase]


name: L-lyxonate = 2-dehydro-3-deoxy-L-arabinonate + H2O


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Schizosaccharomyces pombe)


name: PPP1R3C binds to glycogen:GYG2:GYS2 (Drosophila melanogaster)


name: factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst) (Mus musculus)


name: H2O + trihexanoylglycerol = 2,3-dihexanoyl-sn-glycerol + H(+) + hexanoate


name: FAM83B, (FAM83A, FAM83D) bind EGFR (Gallus gallus)


name: p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP (Drosophila melanogaster)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + cholesterol <=> a 1-acyl-sn-glycero-3-phosphocholine + a cholesterol ester


name: luteolin + S-adenosyl-L-methionine = H(+) + luteolin 7-methyl ether + S-adenosyl-L-homocysteine


name: HTR1A binds HTR1A agonists (Xenopus tropicalis)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Mus musculus)


name: SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Mus musculus)


name: STARD7 transports Q10 to plasma membrane (Caenorhabditis elegans)


name: an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] <=> a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2-O-sulfo-alpha,alpha-trehalose + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + alpha,alpha-trehalose


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycerol


name: loganin + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + secologanin


name: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine


name: PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Drosophila melanogaster)


name: (-)-(R)-19-hydroxytabersonine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (-)-tabersonine + O2 + reduced [NADPH--hemoprotein reductase]


name: MRN complex binds shortened telomeres (Drosophila melanogaster)


name: a sphingosylphosphocholine + H2O = a sphingoid base + H(+) + phosphocholine


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Danio rerio)


name: The complex of ATR and ATRIP is recruited to ICL-DNA (Homo sapiens)


name: IL10 dimer binds IL10RA:JAK1 (Xenopus tropicalis)


name: malate dehydrogenase (decarboxylating) (NADP+) activity


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Gallus gallus)


name: 7-acetyl-epi-neemfruitin B + CoA => acetyl-CoA + epi-neemfruitin B


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Drosophila melanogaster)


name: 3 H(+) + hexadecanoyl-CoA + 3 malonyl-CoA = 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: Misfolded proteins translocate from cilium to cytosol (Homo sapiens)


name: sulfosungeidine E => H(+) + sulfate + sungeidine B


name: SUMOylation of DDX17 with SUMO1 (Dictyostelium discoideum)


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Danio rerio)


name: MSH2:MSH3 binds insertion/deletion loop of 2 bases or more (Saccharomyces cerevisiae)


name: DSCAM/DSCAML1 homodimerization (Drosophila melanogaster)


name: RP2 binds ARL3:GTP:UNC119B (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O <=> a 1,2-diacyl-sn-glycerol + phosphate


name: D-ribulose 1,5-bisphosphate + O2 => (2R)-3-phosphoglycerate + 2-phosphoglycolate + 2 H(+)


name: H(+)(out) + L-histidine(in) + Na(+)(in) => H(+)(in) + L-histidine(out) + Na(+)(out)


name: A + 2 ADP + H(+) + NH4(+) + 2 phosphate => AH2 + 2 ATP + H2O + hydroxylamine


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O => 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Rattus norvegicus)


name: acetyl-CoA + chrodrimanin A <=> chrodrimanin B + CoA


name: NAD(+) + prostaglandin E2 => 15-oxoprostaglandin E2 + H(+) + NADH


name: E2F6 binds RBBP8 gene promoter (Homo sapiens)


name: Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Bos taurus)


name: cyclo(L-arginyl-L-aspartyl) + 2 H(+) + tRNA(Arg) + tRNA(Asp) => L-arginyl-tRNA(Arg) + L-aspartyl-tRNA(Asp)


name: Activated CIT binds KIF14 and PRC1 (Bos taurus)


name: N(2)-(1-hydroxy-2-oxoethyl)-GTP => glyoxal + GTP


name: H(+)(out) + L-aspartate(in) + L-glutamate(out) <=> H(+)(in) + L-aspartate(out) + L-glutamate(in)


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Xenopus tropicalis)


name: H2O + N-acetyl-4-O-acetylneuraminate => acetate + H(+) + N-acetylneuraminate


name: CDC14A,B dephosphorylate p-3S,T MAPK6 (Gallus gallus)


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Rattus norvegicus)


name: H2O + kojibiose = alpha-D-glucose + D-glucose


name: BRAP autoubiquitinates (Caenorhabditis elegans)


name: 2-demethylmenaquinol-7 + S-adenosyl-L-methionine = H(+) + menaquinol-7 + S-adenosyl-L-homocysteine


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphoethanolamine = 1,2-di-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: N-dodecanoyl-heptadecasphing-4-enine-1-phosphoethanolamine => ethanolamine + N-dodecanoyl-heptadecasphing-4-enine-1,3-cyclic phosphate


name: CD38 hydrolyses NAD+ to NAM and ADP-ribose (Canis familiaris)


name: Hydrolysis of PC to PA by PLD (Schizosaccharomyces pombe)


name: ATP + D-tyrosine + tRNA(Tyr) = AMP + D-tyrosyl-tRNA(Tyr) + diphosphate + H(+)


name: 2'-dehydrokanamycin A + H(+) + NADPH <=> kanamycin A + NADP(+)


name: L-gulonate + NADP(+) = aldehydo-D-glucuronate + H(+) + NADPH


name: 2-aminomalonate semialdehyde + H(+) + NADPH => L-serine + NADP(+)


name: NUBPL transfers 4Fe-4S to Complex I subunits (Canis familiaris)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Homo sapiens)


name: NAD(+) + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate = H(+) + NADH + UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate


name: a ganglioside GD3 + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GT3 + CMP + H(+)


name: (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADPH + O2 = (4R,7R)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: TRAF2:cIAP1/2 complex binds FN14:TWEAK (Canis familiaris)


name: Caspase mediated cleavage of HIP-55 (Canis familiaris)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Saccharomyces cerevisiae)


name: CYP1A2, 3A4 oxidise AFB1 to AFNBO (Sus scrofa)


name: NCOA1(868-1441) binds PAX3(1-319) (Mus musculus)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoyl-CoA + 2 H(+) + 2 NADPH => (9Z,12Z)-octadecadien-1-ol + CoA + 2 NADP(+)


name: CHSY1 transfers GalNAc to chondroitin (Rattus norvegicus)


name: Recruitment of AP-2 complex and clathrin (Homo sapiens)


name: CD28 homodimer binds B7-2 monomer (Canis familiaris)


name: pseudouridine(31) in tRNA => uridine(31) in tRNA


name: 21-hydroxyprogesterone + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> corticosterone + H2O + 2 oxidized [adrenodoxin]


name: BTK in G alpha (12)-BTK complex is activated (Canis familiaris)


name: Autophosphorylation of PDGF alpha/beta receptors (Sus scrofa)


name: all-trans-zeaxanthin + 2 UDP-alpha-D-glucose = 2 H(+) + 2 UDP + zeaxanthin bis(beta-D-glucoside)


name: p-Y701-STAT1 dimer translocates from the cytosol to the nucleus (Rattus norvegicus)


name: ERKs are inactivated by dual-specific phosphatases (DUSPs) (Homo sapiens)


name: CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate (Sus scrofa)


name: GDP-beta-L-fucose + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate = GDP + H(+) + methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate


name: LDLR transports extracellular CR:atREs to cytosol  (Homo sapiens)


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Canis familiaris)


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Rattus norvegicus)


name: RUNX3 translocates to the nucleus (Mus musculus)


name: ALD3A1 oxidises 4HPCP to CXPA (Saccharomyces cerevisiae)


name: L-arabinitol + NAD(+) => H(+) + L-ribulose + NADH


name: Active ALK binds SHC1 (Canis familiaris)


name: 1-O-hexadecylglycerone 3-phosphate + H(+) + NADPH = 1-O-hexadecyl-sn-glycero-3-phosphate + NADP(+)


name: 7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Canis familiaris)


name: alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate


name: Initial activation of proMMP2 by MMP1, 7 (Rattus norvegicus)


name: Caspase mediated cleavage of HIP-55 (Bos taurus)


name: Edited Kainate Receptor binds glutamate (Bos taurus)


name: 4-phospho-D-erythronate + NAD(+) => 3-dehydro-4-O-phospho-D-erythronate + H(+) + NADH


name: PE is converted to PS by PTDSS2 (Mus musculus)


name: (2R)-3-sulfolactate <=> H(+) + pyruvate + sulfite


name: Sequestration of BAD protein by 14-3-3 (Mus musculus)


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Canis familiaris)


name: USP21 deubiquitinates RIPK1,DDX58 (Dictyostelium discoideum)


name: NEIL1 cleaves DHU from damaged DNA (Xenopus tropicalis)


name: D-sorbitol 6-phosphate + NADP(+) => aldehydo-D-glucose 6-phosphate + H(+) + NADPH


name: Activated FGFR2 phosphorylates SHC1 (Canis familiaris)


name: 1,2-dioctanoyl-sn-glycero-3-phosphate + H2O => 1,2-dioctanoyl-sn-glycerol + phosphate


name: L-ornithine(out) + N(omega),N(omega)-dimethyl-L-arginine(in) <=> L-ornithine(in) + N(omega),N(omega)-dimethyl-L-arginine(out)


name: Melanin-concentrating hormone receptors bind MCH (Rattus norvegicus)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = (9Z)-octadecenoate + 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + H(+)


name: PAQR3 binds inactive RAFs (Caenorhabditis elegans)


name: a long-chain fatty aldehyde + formyl-CoA => an (R)-2-hydroxy-long-chain-fatty acyl-CoA


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Schizosaccharomyces pombe)


name: I(3,4)P2 is dephosphorylated to I3P by INPP4A/B in the cytosol (Danio rerio)


name: CTSG cleaves CASP1(1-404) (Rattus norvegicus)


name: D-erythrose + phosphate => D-erythrose 4-phosphate + H2O


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + CoA => 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + an acyl-CoA


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Dictyostelium discoideum)


name: Receptors CCR1, 2 and 8 bind CCL16 ligand (Gallus gallus)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O <=> (17E)-cheilanthenediol


name: H(+) + H2O + L-dopa + O2 = 3,4-dihydroxyphenylacetaldehyde + CO2 + H2O2 + NH4(+)


name: Follitropin is a heterodimer (Canis familiaris)


name: 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Homo sapiens)


name: FH tetramer hydrates fumarate to L-malate (Dictyostelium discoideum)


name: eIF5B:GTP is hydrolyzed and released (Drosophila melanogaster)


name: PIAS1 SUMOylates SATB1 with SUMO2,3 (Mus musculus)


name: cytidine(49) in tRNA + S-adenosyl-L-methionine = 5-methylcytidine(49) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: (3R)-3-hydroxy-2,3-dihydrotabersonine + A => (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + AH2


name: SLC7A3 (CAT-3)-mediated uptake of cationic amino acids (Rattus norvegicus)


name: 2-oxoglutarate + 3-methylbutanoyl-CoA + O2 = 2-hydroxy-3-methylbutanoyl-CoA + CO2 + succinate


name: KRAS4B is phosphorylated on serine 181 (Drosophila melanogaster)


name: Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)


name: Association of procollagen type IX (Homo sapiens)


name: (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) => 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Schizosaccharomyces pombe)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => (R,2E)-alpha-cericerene + diphosphate


name: Caspase-9 binds DCC:DIP13alpha complex (Rattus norvegicus)


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Rattus norvegicus)


name: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT (Xenopus tropicalis)


name: (indol-3-yl)acetyl-AMP + CoA <=> (indol-3-yl)acetyl-CoA + AMP + H(+)


name: L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-homocysteine


name: Phosphorylation of beta and gamma subunits by LYN (Homo sapiens)


name: (S)-styrene oxide + FAD + H(+) + H2O => FADH2 + O2 + styrene


name: (2E)-geranyl diphosphate = (1S,5S)-alpha-pinene + diphosphate


name: (2E,6E,10E)-geranylgeranyl diphosphate = diphosphate + talarodiene


name: RAC2 GAPs stimulate RAC2 GTPase activity (Drosophila melanogaster)


name: adenine + alpha-D-ribose 1,5-bisphosphate => AMP + phosphate


name: 1-propanol + 2 Fe(III)-[cytochrome c] <=> 2 Fe(II)-[cytochrome c] + 2 H(+) + propanal


name: CBP and p300 binds NF-kB complex (Drosophila melanogaster)


name: ITPA hydrolyses XTP to XMP (Canis familiaris)


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Homo sapiens)


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Danio rerio)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol => an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside


name: Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Mus musculus)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Rattus norvegicus)


name: Dimerization of Phospho IRF3 or phospho IRF7 (Bos taurus)


name: NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity


name: TGFBR3_mem cleavage by MMPs (Homo sapiens)


name: acetoacetate + CoA + H(+) => acetoacetyl-CoA + H2O


name: EGFR phosphorylates GPNMB (Homo sapiens)


name: ACAD10 dehydrogenates S-2MPDA-CoA (Sus scrofa)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Schizosaccharomyces pombe)


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Homo sapiens)


name: ASIC trimers bind H+ (Rattus norvegicus)


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Sus scrofa)


name: VD3 dissociates from GC (Xenopus tropicalis)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Canis familiaris)


name: a 1,2-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 2-acylglycerol


name: Tetramerization of procollagen VI (Sus scrofa)


name: Binding of ATP to P2X receptors (Xenopus tropicalis)


name: a cytidine in 28S rRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in 28S rRNA + H(+) + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) + lipid A (E. coli) <=> a 1,2-diacyl-sn-glycerol + lipid A hexaacyl 1-(2-aminoethyl diphosphate)


name: (Z)-desulfoglucotropeolin + UDP => (Z)-2-phenyl-1-thioacetohydroximate + UDP-alpha-D-glucose


name: GTSE1 binds microtubule lattice in interphase cells (Xenopus tropicalis)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Canis familiaris)


name: (2Z,6E)-farnesyl diphosphate + 7 isopentenyl diphosphate <=> (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E)-decaprenyl diphosphate + 7 diphosphate


name: GEFs activate RhoA,B,C (Caenorhabditis elegans)


name: RAB31 GEFs exchange GTP for GDP on RAB31 (Saccharomyces cerevisiae)


name: D-aspartyl-tRNA(Asp) + H2O <=> D-aspartate + H(+) + tRNA(Asp)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Rattus norvegicus)


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Mus musculus)


name: NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Bos taurus)


name: H2O + octan-1-ol + 2 oxidized [rubredoxin] => 2 H(+) + O2 + octane + 2 reduced [rubredoxin]


name: AMP(in) + NAD(+)(out) <=> AMP(out) + NAD(+)(in)


name: phycocyanobilin-L-cysteinyl(155)-[phycoerythrocyanin beta-subunit] = (2R,3E)-phycocyanobilin + apo-L-cysteinyl(155)-[phycoerythrocyanin beta-subunit]


name: ADP + H(+) + malonyl-CoA + phosphate => acetyl-CoA + ATP + hydrogencarbonate


name: p-T68-CHEK2 autophosphorylates (Homo sapiens)


name: 15-cis-phytoene + A => AH2 + all-trans-phytofluene


name: DLST transfers succinyl to CoA (Dictyostelium discoideum)


name: GLP1R binds GLP1R agonists (Rattus norvegicus)


name: IL34:CSF1 binds CSF1R (Canis familiaris)


name: 2,5-didehydro-D-gluconate + H(+) + NADPH => 2-dehydro-L-idonate + NADP(+)


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Canis familiaris)


name: H2O + melibiose = D-galactose + D-glucose


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Homo sapiens)


name: WIPI2 binds ATG12:ATG5:ATG16L (Mus musculus)


name: FFAR1:FFAR1 ligands activate Gq (Rattus norvegicus)


name: CDC42 and PIP2 bind WASL, activating it (Sus scrofa)


name: RAC2 GDIs block activation of RAC2 (Bos taurus)


name: PIAS4 SUMOylates PARP1 with SUMO1 (Mus musculus)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Bos taurus)


name: a carboxylate + ATP + H(+) => an acyl-AMP + diphosphate


name: (1R,4R)-dihydrocarvone + H(+) + NADPH + O2 <=> (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O + NADP(+)


name: tRNA pseudouridine(55) synthase activity


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Mus musculus)


name: Oligomerization of CARMA1 (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] => 3-O-{beta-D-galactosyl-(1->3)-[6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: CMP-N-acetyl-beta-neuraminate + ganglioside GA2 (d18:1(4E)/18:0) = CMP + ganglioside GM2 (d18:1(4E)/18:0) + H(+)