name: Exocytosis of specific granule membrane proteins (Rattus norvegicus)


name: Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Drosophila melanogaster)


name: PRKCB (PKC-beta) phosphorylates CARMA1 (Canis familiaris)


name: p-S407,Y641-STAT6 is dimerized (Bos taurus)


name: agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O => 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate


name: alpha-maltotriose + beta-maltose => alpha-maltotetraose + beta-D-glucose


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Canis familiaris)


name: apo-Transferrin dissociates from the receptor complex (Rattus norvegicus)


name: H2O + sn-glycerol 3-phosphocholine = glycerol + H(+) + phosphocholine


name: acetyl-CoA + isomeliandiol = 21-O-acetyl-isomeliandiol + CoA


name: (2E,4S)-4,5-dihydroxypent-2-enal + a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H(+) => a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + H2O


name: SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Canis familiaris)


name: ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate <=> ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate


name: UDP-glucose is oxidised to UDP-glucuronate (Drosophila melanogaster)


name: NEUROG3-dependent synthesis of PAX4 protein (Homo sapiens)


name: p62 recruits an atypical PKC (Sus scrofa)


name: 3',4',5,7-tetrahydroxy-3-methoxyflavone + H(+) + S-adenosyl-L-homocysteine => quercetin + S-adenosyl-L-methionine


name: CoA + O-3-oxobutanoyl-(R)-carnitine => (R)-carnitine + acetoacetyl-CoA


name: H2O + N-(9Z-octadecenoyl)-(4R)-hydroxysphinganine = (4R)-hydroxysphinganine + (9Z)-octadecenoate


name: Dopa is oxidized to dopaquinone by TYR (Bos taurus)


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphate <=> 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Sus scrofa)


name: 3-phenylpropanal + hydrogen cyanide => (2S)-2-hydroxy-4-phenylbutanenitrile


name: cyclohexane-1,3-dione + H2O = 5-oxohexanoate + H(+)


name: CoA + H(+) + N-acyl-1-deoxysphinganine => 1-deoxysphinganine + a fatty acyl-CoA


name: SOD2 gene expression is stimulated by FOXO4, FOXO3 and FOXO1 (Homo sapiens)


name: ATP + isochorismate + L-glutamate <=> AMP + diphosphate + H(+) + isochorismoyl-L-glutamate


name: The COG complex binds RABs at the Golgi membrane (Sus scrofa)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Danio rerio)


name: Formation of MSH1:PMS2 Complex (Bos taurus)


name: SLC25A10 mediates exchange of malate and phosphate (Danio rerio)


name: a 1,2-diacyl-sn-glycerol + a sterol => a 1-acyl-sn-glycerol + a sterol ester


name: 6'-bromomelleolide F + FAD + 2 H2O => bromide + FADH2 + melleolide F + O2


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Bos taurus)


name: Activation of voltage gated Potassium channels (Sus scrofa)


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Dictyostelium discoideum)


name: KIT binds ripretinib (Caenorhabditis elegans)


name: Clustering of Integrin alphaIIb beta3 complexes (Caenorhabditis elegans)


name: 2-oxoglutarate + L-arginyl-[RCC1 domain-containing protein] + O2 <=> (3R)-3-hydroxy-L-arginyl-[RCC1 domain-containing protein] + CO2 + succinate


name: ALDH1A1 oxidises GA to DGA (Schizosaccharomyces pombe)


name: pseudouridine(13) in tRNA => uridine(13) in tRNA


name: (1S,4S)-bornane-2,5-dione + FMNH2 + O2 = (1S,4S)-5-oxo-1,2-campholide + FMN + H(+) + H2O


name: MAP2Ks and MAPKs bind to the activated RAF complex (Sus scrofa)


name: AKT phosphorylates FOXO transcription factors (Homo sapiens)


name: STARD10 binds LPCAT1 and PC (Sus scrofa)


name: oxaloacetate(in) + sulfate(out) = oxaloacetate(out) + sulfate(in)


name: KIR2DS2 interacting with HLA-C group 1 (Cw3) (Mus musculus)


name: Calcineurin binds NFATC1,2,3 (Sus scrofa)


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Sus scrofa)


name: GST trimers transfer GS from GSH to luminal substrates (Drosophila melanogaster)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Canis familiaris)


name: ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Bos taurus)


name: The adrenomedullin receptor can bind adrenomedullin and intermedin (Bos taurus)


name: NAD(+) + pyridoxine = H(+) + NADH + pyridoxal


name: IKKB phosphorylates SNAP23 (Homo sapiens)


name: beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + H(+) + UDP => beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP-alpha-D-galactofuranose


name: Cytosolic VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha  (Mus musculus)


name: Newly formed phosphodiester bond stabilized and PPi released (Homo sapiens)


name: a (2E)-enoyl-CoA + H(+) + NADH => a 2,3-saturated acyl-CoA + NAD(+)


name: AKAP8L binds MLL2 complex (Homo sapiens)


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Xenopus tropicalis)


name: acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH


name: DHCR24 reduces LAN to 24,25-dhLAN (Bos taurus)


name: NUDT18 hydrolyses 8-oxo-GDP to 8-oxo-GMP (Bos taurus)


name: Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: UROD decarboxylates URO1 to COPRO1 (Plasmodium falciparum)


name: [sulfur carrier]-H + L-cysteine <=> [sulfur carrier]-SH + L-alanine


name: PLEKHA8 catalyzes transport of GlcCer to plasma membrane (Mus musculus)


name: (2S)-naringenin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA => (2S)-naringenin 7-O-beta-D-glucoside + malonyl-CoA


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Sus scrofa)


name: 5-phospho-alpha-D-ribose 1-diphosphate + adenine => AMP + diphosphate


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate


name: 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose <=> 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Caenorhabditis elegans)


name: DPEPs hydrolyse glycine from AFXBO-CG, AFNBO-CG (Rattus norvegicus)


name: 2 Fe(III)-[cytochrome c3] + hydrogen sulfide + sulfite = 2 Fe(II)-[cytochrome c3] + thiosulfate


name: FGFR3c binds to FGF (Caenorhabditis elegans)


name: H(+) + NAD(+) + 2 reduced [2Fe-2S]-[putidaredoxin] <=> NADH + 2 oxidized [2Fe-2S]-[putidaredoxin]


name: Fringe-modified Pre-NOTCH is cleaved by FURIN (Mus musculus)


name: a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phosphate + CoA


name: GNRHR binds chemical antagonists (Gallus gallus)


name: (9Z)-octadecenoyl-CoA + 1-O-hexadecylglycerol <=> 1-O-hexadecyl-3-(9Z)-octadecenoylglycerol + CoA


name: NADH + O2 + rifamycin SV => H2O + NAD(+) + rifamycin SV para-naphthoquinone carboxamide


name: (2E,6E)-farnesyl diphosphate + H2O <=> diphosphate + gamma-eudesmol


name: Reduction of presqualene diphosphate to form squalene (Mus musculus)


name: 1-O-hexadecylglycerone 3-phosphate + a fatty acid + H(+) => a 1-acylglycerone 3-phosphate + hexadecan-1-ol


name: v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Gallus gallus)


name: [phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O => [phosphatase 2A protein]-C-terminal L-leucine + H(+) + methanol


name: 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Xenopus tropicalis)


name: AMP + an isonitrile lipopeptide + diphosphate + 2 holo-[ACP] + 2 NADP(+) => 2 a (3R)-3-isocyanyl-fatty acyl-[ACP] + ATP + L-lysine + 2 NADPH


name: NPAS4 translocates to the cytosol (Homo sapiens)


name: Translocation of STAT1 dimer to nucleus (Bos taurus)


name: 2-oxoglutarate + L-aspartyl-[protein] + O2 = 3-hydroxy-L-aspartyl-[protein] + CO2 + succinate


name: G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Caenorhabditis elegans)


name: PIAS1 SUMOylates SATB1 with SUMO1 (Sus scrofa)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Homo sapiens)


name: 4-aminobenzoate + H(+) + pyruvate => 4-amino-4-deoxychorismate


name: TNFAIP3 (A20) ubiquitinates RIPK1 (Canis familiaris)


name: SFTPB dimer,C translocate from multivesicle body to lamellar body (Bos taurus)


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Caenorhabditis elegans)


name: Association of procollagen type XXII (Dictyostelium discoideum)


name: RBP3 regulates the transport of atROL from ROS to RPE (Bos taurus)


name: L protein acts as a cap 2'-O-methyltransferase to modify RSV mRNAs (Homo sapiens)


name: 5-aminoethoxy-methyl-dUMP in DNA + CO2 => 5-O-(L-seryl)-dTMP in DNA + H(+)


name: p-4Y-SIRPA:CD47 binds GRB2-1 (Canis familiaris)


name: taurine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoyl-taurine


name: 4'''-demalonylsalvianin + malonyl-CoA => CoA + salvianin


name: isoscopoletin + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + scoparone


name: an N-acylsphingoid base 1-phosphate(in) = an N-acylsphingoid base 1-phosphate(out)


name: G-protein subunits dissociate from WNT:FZD complex (Gallus gallus)


name: a 1-acyl-sn-glycero-3-phosphate + tetradecanoyl-CoA => a 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: VTN binds collagens II, III and V (Bos taurus)


name: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O = 2 beta-L-arabinofuranose


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA => (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphate


name: Transport of MHC II:Ii complex along Golgi to TGN (Bos taurus)


name: desmosterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24Z),26-hydroxydesmosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: GDIs block activation of RHOA (Drosophila melanogaster)


name: (9Z)-octadecenoate + H2O = 10-hydroxyoctadecanoate


name: SUMOylation of HDAC1 with SUMO1 (Xenopus tropicalis)


name: beta-D-galactosyl-(1<->1')-N-hexadecanoylsphingosine + H2O <=> beta-D-galactose + N-hexadecanoylsphing-4-enine


name: PTPN3 dephosphorylates EPS15 (Rattus norvegicus)


name: an N-acyl-sphingoid base + an oligoglycosyl-(1->4)-D-glucose => an oligoglycosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O


name: Budding of connexon-containing transport vesicles from the Golgi (Danio rerio)


name: Activation of Cdc42 (Xenopus tropicalis)


name: 20S-hydroxycholecalciferol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => 20S,24R-dihydroxycholecalciferol + H2O + 2 oxidized [adrenodoxin]


name: L-lysyl-[protein] + methylglyoxal => N(6)-(1-hydroxy-2-oxopropyl)-L-lysyl-[protein]


name: H2O + L-histidinol phosphate => L-histidinol + phosphate


name: D-cellotriose + O2 = D-cellotriono-1,5-lactone + H2O2


name: Degradation of multiubiquitinated Nek2A (Homo sapiens)


name: NAD(+) + tartrate <=> 2-hydroxy-3-oxosuccinate + H(+) + NADH


name: ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Canis familiaris)


name: YME1L1 proteolyzes unassembled proSMDT1 (Rattus norvegicus)


name: 5alpha-androstan-3,17-dione + A = AH2 + androst-4-ene-3,17-dione


name: 4-methoxy-4-oxo-3-phenylbutanoate + NH4(+) => 2 H2O + methyl 3-cyano-2-phenylpropanoate


name: Aquaporins passively transport glycerol out of cells (Rattus norvegicus)


name: 2-ethylhexanal + CO2 + H(+) + succinate + sulfate => 2-ethylhexyl sulfate + 2-oxoglutarate + O2


name: beta-D-fructose 1-phosphate <=> D-glyceraldehyde + dihydroxyacetone phosphate


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Sus scrofa)


name: 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol <=> 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)


name: a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 3'-phospho-ribonucleotide-RNA + H(+)


name: TDP1 and TDP2 process unligatable DSB ends (Gallus gallus)


name: PMM1,2 isomerise Man6P to Man1P (Sus scrofa)


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Schizosaccharomyces pombe)


name: BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Sus scrofa)


name: (5'S,6'R)-C-glycyluridine + O2 = CO2 + H2O + uridine-5'-carboxamide


name: 2-oxoglutarate + a 3-methyl fatty acyl-CoA + O2 <=> a 2-hydroxy-3-methyl fatty acyl-CoA + CO2 + succinate


name: H(+) + NADH + NH4(+) + octanal => H2O + NAD(+) + octylamine


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 <=> A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O


name: Formation of hair keratin fibres (Sus scrofa)


name: S-adenosyl-L-methionine + uridine(47) in tRNA(Phe) = 3-[(3S)-3-amino-3-carboxypropyl]uridine(47) in tRNA(Phe) + H(+) + S-methyl-5'-thioadenosine


name: a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine


name: (S)-3-amino-3-phenylpropanoate + 2-oxoglutarate = 3-oxo-3-phenylpropanoate + L-glutamate


name: H2O + streptothricin D => streptothricin D acid


name: SEC4C,D bind GOSR2 and STX5 (Sus scrofa)


name: FGFR1c binds to Klotho-bound FGF23 (Gallus gallus)


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Mus musculus)


name: 1-tetracosanoylglycerol + H2O => glycerol + H(+) + tetracosanoate


name: SUMOylation of HIPK2 with SUMO1 (Schizosaccharomyces pombe)


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Canis familiaris)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Mus musculus)


name: 7-oxo-25-hydroxycholesterol + H(+) + NADPH => 7beta-25-dihydroxycholesterol + NADP(+)


name: OPTN recruits CYLD to the TNFR1 complex (Homo sapiens)


name: iodide(in) + 2 Na(+)(in) => iodide(out) + 2 Na(+)(out)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Gallus gallus)


name: The Interleukin 1 receptor complex binds Tollip (Mus musculus)


name: H2O + peracetic acid => acetate + H(+) + H2O2


name: CoB--CoM heterodisulfide reductase activity


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Mus musculus)


name: ATP + NH4(+) + UTP => ADP + CTP + 2 H(+) + phosphate


name: Secreted CD14 binds LPS (Canis familiaris)


name: 15alpha-stemmadenine + acetyl-CoA => CoA + O-acetyl-15alpha-stemmadenine


name: MSL acetylates histone H4 (Canis familiaris)


name: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O


name: H2O + O2 + pyridoxamine 5'-phosphate => H2O2 + NH4(+) + pyridoxal 5'-phosphate


name: 2-oxoglutarate + N(omega),N(omega)-dimethyl-L-arginyl-[protein] + O2 => CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate


name: atREs binds to nascent CM (Canis familiaris)


name: a fatty acid + H(+) + N-acyl-sn-glycero-3-phosphoethanolamine => H2O + N,1-diacyl-sn-glycero-3-phosphoethanolamine


name: CYSLTR1 binds CYSLTR1 antagonists (Drosophila melanogaster)


name: USP19 binds HIF1A,BIRC2,BIRC3 (Canis familiaris)


name: Cytosolic PLK1 translocates to the nucleus (Schizosaccharomyces pombe)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Gallus gallus)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Rattus norvegicus)


name: OCT1 transports organic cations into hepatic cells (Sus scrofa)


name: TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Homo sapiens)


name: (2E)-butenoyl-[ACP] + H(+) + NADPH = butanoyl-[ACP] + NADP(+)


name: GGCX gamma-carboxylates PROZ(24-400) (pro-protein Z) (Rattus norvegicus)


name: BRCA1 binds phosphorylated RBBP8 (Gallus gallus)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Sus scrofa)


name: (E)-cinnamyl alcohol + acetyl-CoA <=> (E)-cinnamyl acetate + CoA


name: 2,3-epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O => (3Z)-6-oxohex-3-enoyl-CoA + formate + H(+)


name: ARSA removes sulfate from SM3 (Bos taurus)


name: IL10 dimer binds IL10RA:JAK1 (Danio rerio)


name: Hemes bind to CLEC1B dimer (Rattus norvegicus)


name: RISC binds inexactly matching target RNAs (Rattus norvegicus)


name: H2O + O2 + pyridoxal = 4-pyridoxate + H(+) + H2O2


name: L-cysteinyl-[protein] + tetradecanoyl-CoA => CoA + S-tetradecanoyl-L-cysteinyl-[protein]


name: SLC37A1, SLC37A2 exchange G6P for Pi across the ER membrane (Canis familiaris)


name: GEF binds to the inactive DRheb (Drosophila melanogaster)


name: cadaverine(in) + L-lysine(out) => cadaverine(out) + L-lysine(in)


name: activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Bos taurus)


name: 4alpha-hydroxymethyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: p-T38-PPP1R14A binds MLCP (Caenorhabditis elegans)


name: coenzyme F420-0 gamma-glutamyl ligase activity


name: GTP-bound RAC contributes to JNK activation (Danio rerio)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ATP + H2O => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ADP + H(+) + phosphate


name: 4-(hydroxymethyl)benzenesulfonate + NAD(+) <=> 4-formylbenzenesulfonate + H(+) + NADH


name: a quinol + 4 H(+)(out) + NADP(+) => a quinone + 5 H(+)(in) + NADPH


name: ATP + CoA + isophthalate <=> AMP + diphosphate + isophthalyl-CoA


name: 2 sucrose => 6-kestotriose + beta-D-glucose


name: geranylgeranyl diphosphate + H2O => (S)-(+)-nephthenol + diphosphate


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Canis familiaris)


name: RAB3GAP1:RAB3GAP2 promotes nucleotide exchange on RAB18 (Gallus gallus)


name: FH tetramer hydrates fumarate to L-malate (Caenorhabditis elegans)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Rattus norvegicus)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Mus musculus)


name: ITPA hydrolyses XTP to XMP (Caenorhabditis elegans)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Homo sapiens)


name: 2 hydrogencarbonate(in) + sulfate(out) => 2 hydrogencarbonate(out) + sulfate(in)


name: (3R,4R)-3-(6-hydroxy-1,3-benzodioxol-5-yl)-3,4-dihydro-2H-chromene-4,7-diol = (-)-maackiain + H2O


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Rattus norvegicus)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Rattus norvegicus)


name: p-VAV family:PIP3 binds RAC1:GDP (Gallus gallus)


name: L-phenylalanine(in) + L-tryptophan(out) => L-phenylalanine(out) + L-tryptophan(in)


name: BTNL9 binds immune cell surfaces (Bos taurus)


name: H2O + NAD(+) + octadecanal => 2 H(+) + NADH + octadecanoate


name: glyoxylate + L-2-aminoadipate = 2-oxoadipate + glycine


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Gallus gallus)


name: H2O + taurochenodeoxycholate <=> chenodeoxycholate + taurine


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA <=> (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H2O


name: PTPRF, PTPRS, PTPRD bind Liprins (Gallus gallus)


name: Activated FGFR3 phosphorylates FRS2 (Bos taurus)


name: Transport of L1 into endosomes (Schizosaccharomyces pombe)


name: iE-DAP elicits a NOD1 response (Canis familiaris)


name: p-S215 FOXO3 translocates to the nucleus (Mus musculus)


name: Phosphorylation of COP1 at Ser-387  by ATM (Bos taurus)


name: Activated TLR4:TICAM1 recruits TRAF6 (Sus scrofa)


name: ALPK1:ADP-heptose binds TIFA (Xenopus tropicalis)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Xenopus tropicalis)


name: RFC dissociates after sliding clamp formation (Dictyostelium discoideum)


name: XPO1-dependent export of p-S69,S73 MITF-M (Homo sapiens)


name: AMP + diphosphate + H(+) + L-isoleucine-(+)-7-isojasmonate => (+)-7-isojasmonate + ATP + L-isoleucine


name: 2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 2-(9Z-octadecenoyl)-glycerol + phosphate


name: PPP1CC dephosphorylates PLK1 (Mus musculus)


name: SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)


name: ABCA5 transports CHOL from lysosomal lumen to cytosol (Bos taurus)


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Danio rerio)


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Bos taurus)


name: GRIN2A gene expression is stimulated by MECP2 (Homo sapiens)


name: 2,4,6-trinitrotoluene + 2 H(+) + 2 NADPH => 4-hydroxylamino-2,6-dinitrotoluene + H2O + 2 NADP(+)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O <=> beta-D-glucosylceramide + D-galactose


name: Caspase-mediated cleavage of Desmoplakin (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] = (13R)-hydroxy-(9Z,11E)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 AH2 = (8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 A + 2 H2O


name: Activated NOD oligomer recruites RIP2 (RICK) (Mus musculus)


name: CYP19A1 hydroxylates ANDST to E1 (Homo sapiens)


name: G protein-coupled serotonin receptor binding


name: TTPA binds alpha-TOH (Dictyostelium discoideum)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Mus musculus)


name: LHPP:Mg2+ dimer hydrolyses PPi (Mus musculus)


name: cytidine(2278) in 25S rRNA + S-adenosyl-L-methionine => 5-methylcytidine(2278) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine


name: a fatty acid + taurine => an N-fatty acyl-taurine + H2O


name: Translocation of Cyclin E:Cdk2 complex to the nucleus (Drosophila melanogaster)


name: SUMOylation of HDAC2 with SUMO1 (Saccharomyces cerevisiae)


name: The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Sus scrofa)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Dictyostelium discoideum)


name: xylulose 5-phosphate <=> D-ribulose 5-phosphate (Sus scrofa)


name: beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP-beta-L-colitose <=> alpha-L-colitosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine + GDP + H(+)


name: Autophosphorylation of SRC (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol <=> a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) (Sus scrofa)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Mus musculus)


name: beta-alanine(in) + H(+)(in) = beta-alanine(out) + H(+)(out)


name: a phosphatidylglycerol phosphate + H2O = a phosphatidylglycerol + phosphate


name: USP33 deubiquitinates ROBO1 (Homo sapiens)


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Bos taurus)


name: MET dimers autophosphorylate (Caenorhabditis elegans)


name: ABC-type oligogalacturonide transporter activity


name: Activated MAPKs phosphorylate MAP2K1 (Rattus norvegicus)


name: 9alpha,11alpha-methylene thromboxane A2 + O2 + reduced [NADPH--hemoprotein reductase] => 19-hydroxy-9alpha,11alpha-methylene thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: bis(beta-D-gentiobiosyl) crocetin + H(+) + UDP => beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP-alpha-D-glucose


name: Phosphorylated ERF translocates to the cytosol (Danio rerio)


name: [deoxyhypusine synthase]-L-lysine + [eIF5A protein]-N-(4-aminobutylidene)-L-lysine => [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + [eIF5A protein]-L-lysine


name: glutarate(in) + urate(out) => glutarate(out) + urate(in)


name: 5-formimidoyltetrahydrofolate + 2 H(+) = (6R)-5,10-methenyltetrahydrofolate + NH4(+)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Drosophila melanogaster)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Mus musculus)


name: calciol + O2 + reduced [NADPH--hemoprotein reductase] => calcidiol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Capping complex formation (Saccharomyces cerevisiae)


name: 1,2-dioctanoyl-sn-glycerol + CDP-choline <=> 1,2-dioctanoyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Drosophila melanogaster)


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Mus musculus)


name: ethanol + NAD+ => acetaldehyde + NADH + H+ (Canis familiaris)


name: GNAT1-GDP binds to GNB1:GNGT1 (Homo sapiens)


name: (R)-5-phosphomevalonate + ATP = ADP + CO2 + isopentenyl phosphate + phosphate


name: Formation of hydroxylysyl-pyrrole cross-links (Xenopus tropicalis)


name: SOS1-mediated nucleotide exchange of RAS (HB-EFG-initiated) (Xenopus tropicalis)


name: 1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)-cholecalciferol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 1alpha,25-dihydroxy-2beta-(1,3-dihydroxypropoxy)-cholecalciferol + 2 Fe(III)-[cytochrome b5] + H2O


name: DAG activation of TRPC channels (Canis familiaris)


name: Collagen type VIII degradation by MMP1 (Gallus gallus)


name: PPP1R3C binds to glycogen:GYG1:GYS1 (Drosophila melanogaster)


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Homo sapiens)


name: Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane (Bos taurus)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Danio rerio)


name: Formation of Malonyl-CoA from Acetyl-CoA (liver) (Mus musculus)


name: 1-(9Z,12Z-octadecadienoyl)-2-acyl-3-[beta-D-galactosyl]-sn-glycerol + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-3-[beta-D-galactosyl]-sn-glycerol + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Cytosolic DUSPs dephosphorylate MAPKs (Xenopus tropicalis)


name: beta-alanine + L-ornithine => beta-alanyl-L-ornithine + H2O


name: an alpha-L-rhamnosyl-(1->4)-beta-D-glucuronide = a 4-deoxy-alpha-L-threo-hex-4-enopyranuronoside + L-rhamnopyranose


name: ACAD11 dehydrogenates BH-CoA (Homo sapiens)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII (Drosophila melanogaster)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Mus musculus)


name: a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+) + N(7)-methyl-GMP => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O


name: CYSLT2 binds LTC4,LTD4,LTE4 (Gallus gallus)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Bos taurus)


name: Cytosolic PLK1 translocates to the nucleus (Dictyostelium discoideum)


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)


name: 3-oxohexacosanoyl-CoA + CoA => acetyl-CoA + tetracosanoyl-CoA


name: 3-oxosphinganine + decanoyl-CoA <=> CoA + H(+) + N-decanoyl-3-oxosphinganine


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 1D-myo-inositol 1,3,4-trisphosphate <=> 1D-myo-inositol 1,3,4,6-tetrakisphosphate + 1D-myo-inositol 3,4,5,6-tetrakisphosphate


name: Alpha-defensins form biologically active dimers (Rattus norvegicus)


name: 3,4-dihydroxybenzoate + 2 H(+) + NADH + O2 = benzene-1,2,4-triol + CO2 + H2O + NAD(+)


name: H(+)(in) + L-lysyl-glycine(in) => H(+)(out) + L-lysyl-glycine(out)


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Gallus gallus)


name: 1-acyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + H2O <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Sus scrofa)


name: (9E)-octadecenoyl-CoA + H2O => (9E)-octadecenoate + CoA + H(+)


name: Translocation of PMAIP1 (NOXA) to mitochondria (Homo sapiens)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O


name: 12-methyloctadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA = 4-hydroxy-6-(11-methylheptadecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: 3-(3-hydroxyphenyl)-propanoyl-CoA + 3 H(+) + 3 malonyl-CoA <=> 3,3',5-trihydroxybibenzyl + 4 CO2 + 4 CoA


name: alpha-2-antiplasmin + plasmin -> alpha-2-antiplasmin:plasmin (Bos taurus)


name: DHTKD1 dimer decarboxylates 2-OA (Bos taurus)


name: (S)-3-hydroxyisobutanoyl-CoA => (2E)-2-methylpropenoyl-CoA + H2O


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Caenorhabditis elegans)


name: CREBBP acetylates histone H2B, H3, H4 (Homo sapiens)


name: RBBP8 gene expression is inhibited by E2F6 (Homo sapiens)


name: 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA => 8 H(+) + malonamoyl-[OxyC ACP] + 8 malonyl-CoA


name: 5-acetamidopentanoate + H2O = 5-aminopentanoate + acetate


name: POLD,POLE-mediated DNA strand displacement synthesis (Plasmodium falciparum)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Mus musculus)


name: CYB5A:heme reduces Asc.- to AscH- (Dictyostelium discoideum)


name: a di-trans,poly-cis-dolichyl D-xylosyl phosphate  + L-seryl-[protein] => 3-O-(beta-D-xylosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)


name: 2-hydroxy-1-phenyl-1-propanone + NADP(+) = 1-phenyl-1,2-propanedione + H(+) + NADPH


name: IGF1R phosphorylates SHC1 (Gallus gallus)


name: Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)


name: chlorophyll a + 2 H(+) => Mg(2+) + pheophytin a


name: L-seryl-[protein] + NAD(+) <=> H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-seryl-[protein]


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Saccharomyces cerevisiae)


name: a quinone + H2O + methanol => a quinol + methane + O2


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Sus scrofa)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O = (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H(+)


name: a fatty acyl-AMP + diphosphate => a fatty acid + ATP + H(+)


name: Membrane estrogen receptors bind SRC (Mus musculus)


name: 4-hydroxyestrone + O2 <=> (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: n 3'-phosphoadenylyl sulfate + dermatan <=> n adenosine 3',5'-bisphosphate + dermatan 4'-sulfate + n H(+)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Rattus norvegicus)


name: 16-hydroxyhexadecanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4-hydroxy-6-(17-hydroxy-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] => glyoxal + L-cysteinyl-[protein]


name: MLKL binds FLOT1, FLOT2 (Rattus norvegicus)


name: Phosphorylated FLT3 fusions bind GRB2 (Homo sapiens)


name: H2O + S-benzyl-L-cysteinylglycine => glycine + S-benzyl-L-cysteine


name: alpha-maltoheptaose + phosphate <=> alpha-D-glucose 1-phosphate + alpha-maltohexaose


name: p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Homo sapiens)


name: MFSD2A transports LPC from extracellular region to plasma membrane (Homo sapiens)


name: p-Y389,400-RUFY1 binds RAB4A:GTP, RAB5:GTP, RAB14:GTP (Bos taurus)


name: USP13 and OTUD3 deubiquitinate PTEN (Danio rerio)


name: UBXN1 binds BRCA1:BARD1 heterodimer (Mus musculus)


name: NADP(+) + ubiquinol-8 => H(+) + NADPH + ubiquinone-8


name: GNE hydrolyzes/epimerises UDP-GlcNAc to ManNAc and UDP (Danio rerio)


name: S100A8:S100A9 binds Mn2+ (Rattus norvegicus)


name: a short-chain (3R)-hydroxy fatty acyl-CoA = a short-chain (2E)-enoyl-CoA + H2O


name: ADP + H(+) + phosphate + voriconazole(out) => ATP + H2O + voriconazole(in)


name: S-adenosyl-L-methionine + scutellarein => H(+) + S-adenosyl-L-homocysteine + scutellarein 4'-methyl ether


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Bos taurus)


name: Formation of CDK4/6:CCND complexes (Gallus gallus)


name: CPT2 converts palmitoyl carnitine to palmitoyl-CoA (Mus musculus)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 1-O-methyl (5Z,8Z,10E,12R,14Z)-hydroperoxyiecosatetraenoate


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Homo sapiens)


name: H2O + IMP + NAD(+) <=> H(+) + NADH + XMP


name: H(+) + holo-[ACP] + N(6)-[(9Z)-hexadecenoyl]-L-lysyl-[protein] => (9Z)-hexadecenoyl-[ACP] + L-lysyl-[protein]


name: N-WASP binds ARP2/3 and G-actin (Homo sapiens)


name: 2-aminocyclohexanol + H2O + NAD(+) => 2-hydroxycyclohexan-1-one + H(+) + NADH + NH4(+)


name: EXA4 is converted to EXC4 by LTC4S (Bos taurus)


name: LIG1 binds POLB at long-patch BER site (Mus musculus)


name: alpha-maltotetraose + phosphate = alpha-D-glucose 1-phosphate + alpha-maltotriose


name: NS2 (1B) mRNA is translated into protein NS2 (Homo sapiens)


name: Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B (Gallus gallus)


name: CDK2 phosphorylates RBBP8 (Gallus gallus)


name: (9Z)-octadecenoate + L-glutamine => H2O + N-(9Z-octadecenoyl)-L-glutamine


name: Defective HEXA does not cleave the terminall GalNAc from small HA fragments (Homo sapiens)


name: FANCD2 deubiquitination by USP1:WDR48 (Gallus gallus)


name: CoA + H(+) + N-(9Z-octadecanoyl)-dopamine => (9Z)-octadecenoyl-CoA + dopamine


name: WDR5 binds Me2sR3-replicative histone H3 (Canis familiaris)


name: "sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)"


name: epiandrosterone 3-beta-D-glucoside + H(+) + UDP => 3beta-hydroxy-5alpha-androstan-17-one + UDP-alpha-D-glucose


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Dictyostelium discoideum)


name: decan-1-ol + hexadecanoyl-CoA = CoA + decanyl hexadecanoate


name: 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine => adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine


name: Dimerization of LIMK1 by Hsp90 (Xenopus tropicalis)


name: Dehalogenation of carbon tetrachloride to form a free radical (Homo sapiens)


name: NEU2 cleaves GM3 to form LacCer (cytosol) (Mus musculus)


name: 2 (E)-sinapoyl-CoA + spermidine => 2 CoA + 2 H(+) + N(1),N(8)-bis[(E)-sinapoyl]-spermidine


name: POU5F1 (OCT4), SOX2, NANOG bind the EOMES promoter (Homo sapiens)


name: Activated NOD1 oligomerizes (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + dopamine <=> CoA + H(+) + N-(9Z-octadecanoyl)-dopamine


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Schizosaccharomyces pombe)


name: (2E,12Z,15Z,18Z,21Z,24Z,27Z)-triacontaheptaenoyl-CoA + H(+) + NADPH = (12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Dictyostelium discoideum)


name: (+)-penichrysol + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: Passive I- efflux mediated by SLC5A8 (Danio rerio)


name: IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)


name: histone H2AR3 arginine deiminase activity


name: 2-oxoglutarate + clavatol + O2 => CO2 + hydroxyclavatol + succinate


name: NTRK3 dimers trans-autophosphorylate (Bos taurus)


name: RAC3 GEFs activate RAC3 (Caenorhabditis elegans)


name: SRF binds NPAS4 gene promoter (Homo sapiens)


name: P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential


name: POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Drosophila melanogaster)


name: PRC1 SUMOylates CTBP1 with SUMO2,3 (Xenopus tropicalis)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Xenopus tropicalis)


name: dAMP(in) + NAD(+)(out) = dAMP(out) + NAD(+)(in)


name: Release of E3 from polyubiquitinated substrate (Sus scrofa)


name: SMURF1/2 ubiquitinates PRICKLE1 (Danio rerio)


name: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + H2O <=> 1D-myo-inositol 1,4,5-trisphosphate + phosphate


name: L-asparaginyl-[protein] + UDP-alpha-D-glucose <=> H(+) + N(4)-(beta-D-glucosyl)-L-asparaginyl-[protein] + UDP


name: CBL ubiquitinates FRS2 and FGFR3 (Drosophila melanogaster)


name: 2 H(+) + NADH + 2 O2 + protoviolaceinate => CO2 + 2 H2O + NAD(+) + violacein


name: ERBB3 binds RNF41 ubiquitin ligase (Danio rerio)


name: Multi-ubiquitination of APOBEC3G (Homo sapiens)


name: ST6GALNAC5,6 transfer Neu5Ac to GM1b (Bos taurus)


name: allodeoxycholoyl-CoA + cholate <=> allodeoxycholate + choloyl-CoA


name: ADP-L-glycero-beta-D-manno-heptose + L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) = ADP + H(+) + L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: PP2A dephosphorylates BANF1 (Canis familiaris)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Drosophila melanogaster)


name: activated MEK2 phosphorylates ERK2 (Gallus gallus)


name: dodecanoate + O2 => (2R)-2-hydroperoxydodecanoate


name: a 2'-O-methylribonucleotide in RNA + H(+) + S-adenosyl-L-homocysteine => a ribonucleotide in RNA + S-adenosyl-L-methionine


name: 2,3-didodecanoyl-sn-glycerol + dodecanoate + H(+) => H2O + tridodecanoylglycerol


name: (E)-coniferol + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-(E)-coniferol + H(+) + UDP


name: galactitol + NADP(+) => D-galactose + H(+) + NADPH


name: NUDT16 hydrolyses dIDP to dIMP (Rattus norvegicus)


name: Formation of the MLL3 complex (Caenorhabditis elegans)


name: Activation of RAC1 by VAV2/3 (Drosophila melanogaster)


name: Activated FGFR2 binds SHC1 (Homo sapiens)


name: AH2 + O2 + preaustinoid A <=> A + H2O + preaustinoid A1


name: ATP7A transports cytosolic Cu2+ to extracellular region (Xenopus tropicalis)


name: CoA + NAD(+) + pyruvate => acetyl-CoA + CO2 + NADH


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Mus musculus)


name: Dimerization of p-S446-IRF5 (Canis familiaris)


name: IL11:IL11RA binds IL6ST:JAK1,JAK2,(TYK2) (Rattus norvegicus)


name: acetyl-CoA + isomeliandiol <=> 21-O-acetyl-isomeliandiol + CoA


name: succinate(in) + urate(out) <=> succinate(out) + urate(in)


name: MYLIP dimer ubiquitinates VLDLR on Lys-839 (Rattus norvegicus)


name: GAA hydrolyzes lysosomal glycogen (Sus scrofa)


name: Formation of active mTORC1 complex (Rattus norvegicus)


name: (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + sn-glycerol 3-phosphocholine => 2-[(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O


name: dGDP(out) + UTP(in) = dGDP(in) + UTP(out)


name: albendazole + O2 + reduced [NADPH--hemoprotein reductase] <=> albendazole S-oxide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2E,6E)-farnesyl diphosphate + H2O = diphosphate + palustrol


name: (2E)-geranyl diphosphate + 2-O,3-dimethylflaviolin + H(+) <=> 7-O-geranyl-2-O,3-dimethylflaviolin + diphosphate


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Schizosaccharomyces pombe)


name: A + all-trans-lycopene = AH2 + all-trans-3,4-didehydrolycopene


name: a 1-acyl-sn-glycero-3-phosphate + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA


name: a quinol + CO2 => a quinone + formate + H(+)


name: an (E)-omega-(methylsulfanyl)-alkanal oxime + O2 + reduced [NADPH--hemoprotein reductase] <=> a (1E)-1-aci-nitro-omega-(methylsulfanyl)alkane + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine <=> [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + dodecanoyl-CoA <=> 1,2-di-(9Z)-octadecenoyl-3-dodecanoyl-sn-glycerol + CoA


name: 3-methyl-(2E)-butenoyl-CoA + ATP + hydrogencarbonate = 3-methyl-(2E)-glutaconyl-CoA + ADP + H(+) + phosphate


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Canis familiaris)


name: CO2 + D-ribulose 1,5-bisphosphate + H2O => 2 (2R)-3-phosphoglycerate + 2 H(+)


name: KCNJ11:ABCC9 binds nicorandil (Gallus gallus)


name: 2-oxoglutarate + acetyl-CoA + H2O = (2R)-homocitrate + CoA + H(+)


name: GRB2:SOS1 complex binds to the active receptor (Xenopus tropicalis)


name: noranthrone + O2 => H2O + norsolorinic acid


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Homo sapiens)


name: adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate + H(+) => 3'-phosphoadenylyl sulfate + 3beta-hydroxyandrost-5-en-17-one


name: (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2


name: ADP + gamma-L-glutamyl-isopropylamide + H(+) + phosphate => ATP + isopropylamine + L-glutamate


name: ATP + D-lysine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate <=> ADP + H(+) + N(6)-(UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl)-D-lysine + phosphate


name: 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = CoA + H(+) + mycothiol


name: Phosphorylation of complexed TSC2 by PKB (Homo sapiens)


name: ATP + CoA + pentadecanoate = AMP + diphosphate + pentadecanoyl-CoA


name: PTGIR binds PTGIR agonists (Drosophila melanogaster)


name: NAD(+) + prostaglandin E1 => 15-oxoprostaglandin E1 + H(+) + NADH


name: KRAB-ZNF / KAP Interaction (Homo sapiens)


name: Agmatine + H2O <=> putrescine + urea (Rattus norvegicus)


name: Interleukin-1 family are secreted (Danio rerio)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)


name: IL1R1:IL1:IL1RAP:MYD88 homodimer binds IRAK4 (Sus scrofa)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Xenopus tropicalis)


name: 3-phosphooxypyruvate + H2O <=> 3-hydroxypyruvate + phosphate


name: Oligomerization of p-CARMA1 (Rattus norvegicus)


name: a medium-chain (3R)-hydroxyacyl-CoA => a medium-chain (2E)-enoyl-CoA + H2O


name: (20S)-hydroxypregn-4-en-3-one + NAD(+) = H(+) + NADH + progesterone


name: PRDX3,5 catalyze TXN2 reduced + H2O2 => TXN2 oxidized + 2H2O (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PRKCI phosphorylates NFE2L2 (Danio rerio)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + octadecanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-octadecanoyl-sn-glycerol + CoA


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + H(+) + NADPH = 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP(+)


name: YME1L1 binds mitochondrial inner membrane proteins (Homo sapiens)


name: Trans-autophosphorylation of ERBB4 homodimers (Gallus gallus)


name: p-6Y-VEGFR2 binds PLCG1 (Xenopus tropicalis)


name: Phosphorylation of YAP by LATS2 (Rattus norvegicus)


name: Hydrolysis of PC to PA by PLD (Sus scrofa)


name: RHOB GAPs stimulate RHOB GTPase activity (Caenorhabditis elegans)


name: Thrombin-activated PARs binds G-protein Gq (Sus scrofa)


name: p-Y-STATs dimerize (Drosophila melanogaster)


name: H2O + N-(15Z-tetracosenoyl)-taurine = (15Z)-tetracosenoate + taurine


name: a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: peregrinol diphosphate synthase activity


name: pyridine + S-adenosyl-L-methionine <=> N-methylpyridinium + S-adenosyl-L-homocysteine


name: Loss of Rrn3 from RNA Polymerase I promoter escape complex (Saccharomyces cerevisiae)


name: Recruitment of Dna2 endonuclease (Homo sapiens)


name: Phospho FT reduces D accumulation at the plasma membrane (Drosophila melanogaster)


name: uridine(35) in tRNA(Tyr) <=> pseudouridine(35) in tRNA(Tyr)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O => 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+)


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-2,6-dideoxy-D-glycero-hex-2-enos-4-ulose + H2O


name: AMP + diphosphate + H(+) + putrebactin => ATP + pre-putrebactin


name: PTPN11:p-STAT5 binds BCL2L1 promoter (Homo sapiens)


name: ATP + beta-D-fructose = ADP + beta-D-fructose 1-phosphate + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O => a fatty acid + a monoacyl-sn-glycero-3-phosphocholine + H(+)


name: ACSL3,4 ligate CoA to AA to form AA-CoA (Xenopus tropicalis)


name: (2E,6E)-farnesyl diphosphate = (S)-beta-bisabolene + diphosphate


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Sus scrofa)


name: Formation of MCM2-7 complex (Bos taurus)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Canis familiaris)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Canis familiaris)


name: (9Z,12Z)-octadecadienoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol <=> 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + CoA


name: HSPG2 (perlecan) is cleaved by BMP1, TLL1, TLL2, Cathepsin L1 (Homo sapiens)


name: RNF5 and RNF185 ubiquitinate CFTR F508del (Homo sapiens)


name: KDM4A,B bind H4K20Me2 (Saccharomyces cerevisiae)


name: H2O + phloretin = 1,3,5-trihydroxybenzene + H(+) + phloretate


name: Defective GAA does not hydrolyze lysosomal glycogen (Homo sapiens)


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Bos taurus)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Bos taurus)


name: P2X7 mediates loss of intracellular K+ (Canis familiaris)


name: Interaction of GPVI and FceRI gamma (Sus scrofa)


name: spermine oxidase (propane-1,3-diamine-forming) activity


name: p-S92,203-BRF1 binds 14-3-3 (Drosophila melanogaster)


name: a 2'-unsubstituted isoflavone + O2 + reduced [NADPH--hemoprotein reductase] => a 2'-hydroxyisoflavone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Recruitment of STATs (Rattus norvegicus)


name: ATP + H2O + kainate(in) = ADP + H(+) + kainate(out) + phosphate


name: Autocatalytic phosphorylation of FGFR3 cysteine mutants (Homo sapiens)


name: 2-dehydro-3-deoxy-L-fuconate + H2O => L-fuconate


name: sucrose + UDP-alpha-D-galactose <=> 6(F)-alpha-D-galactosylsucrose + H(+) + UDP


name: GBF1 stimulates ARF nucleotide exchange (Homo sapiens)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Homo sapiens)


name: (3R)-3-hydroxybutanoyl-CoA + H2O = (R)-3-hydroxybutanoate + CoA + H(+)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Saccharomyces cerevisiae)


name: acetaldehyde + H(+) + sulfite => 2-hydroxyethane-1-sulfonate


name: H(+)(out) + L-idonate(out) => H(+)(in) + L-idonate(in)


name: RAC3 GDIs block activation of RAC3 (Homo sapiens)


name: AMY1-3 bind IAPP(34-70) (Xenopus tropicalis)


name: DEGS1 dehydrogenates dihydroceramide (Mus musculus)


name: D-glucose + D-glucose 1,6-bisphosphate => 2 D-glucopyranose 1-phosphate


name: D-threo-isocitrate + NAD(+) = 2-oxoglutarate + CO2 + NADH


name: PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins (Gallus gallus)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Caenorhabditis elegans)


name: 2 ATP + 2 indole-3-pyruvate = 2 AMP + didemethylasterriquinone D + 2 diphosphate + H(+)


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Homo sapiens)


name: OCT1 transports organic cations into hepatic cells (Drosophila melanogaster)


name: ATP + L-proline + tRNA(Pro) => AMP + diphosphate + L-prolyl-tRNA(Pro)


name: 2,5-didehydro-D-gluconate + H(+) + NADPH => 2-dehydro-D-gluconate + NADP(+)


name: L-2-hydroxycarboxylate dehydrogenase (NAD+) activity


name: 2-acyl LPI is acylated to PI by MBOAT7 (Homo sapiens)


name: phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP (Sus scrofa)


name: D-glucose 6-sulfate + H2O => D-glucose + H(+) + sulfate


name: 2-(2-methylsulfanyl)propylmaleate + H2O => 3-(3-methylsulfanyl)propylmalate


name: HDAC10 deacetylates histone (Canis familiaris)


name: CBL neddylates TGFBR2 (Canis familiaris)


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)


name: cholate + deoxycholoyl-CoA = choloyl-CoA + deoxycholate


name: FUT1,2 transfer fucose to gangliosides (Mus musculus)


name: 12-phosphooxy-(9E)-octadecenoate + H2O => 12-hydroxy-(9E)-octadecenoate + phosphate


name: blasticidin S + H(+) + H2O => deaminohydroxyblasticidin S + NH4(+)


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Mus musculus)


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Xenopus tropicalis)


name: H2O + N-decanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-decanoyl ethanolamine


name: 9H-fluoren-9-ol + NADP(+) => 9H-fluoren-9-one + H(+) + NADPH


name: H(+) + indolmycin + S-adenosyl-L-homocysteine => N-demethylindolmycin + S-adenosyl-L-methionine


name: MATEs mediate extrusion of xenobiotics (Mus musculus)


name: (1S,4R)-menthone + H(+) + NADPH + O2 = (4S,7R)-7-isopropyl-4-methyloxepan-2-one + H2O + NADP(+)


name: IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Sus scrofa)


name: ADP + H(+) + Pb(2+)(out) + phosphate => ATP + H2O + Pb(2+)(in)


name: TFAP2C homodimer binds MYC and KDM5B (Danio rerio)


name: ATP + H2O + phenol <=> AMP + 2 H(+) + phenyl phosphate + phosphate


name: Inactivation of Cyclin A:Cdk2 complexes by p27/p21 (Mus musculus)


name: 2 Fe(III)-[cytochrome c] + H2O + hexanal = 2 Fe(II)-[cytochrome c] + 3 H(+) + hexanoate


name: 2-epi-5-epi-valiolone 7-phosphate + ADP + H(+) => 2-epi-5-epi-valiolone + ATP


name: 2 Fe(III)-[cytochrome c] + H2O + thiocyanate = cyanate + 2 Fe(II)-[cytochrome c] + 2 H(+) + sulfur


name: Export of peptide loaded MHC class I complex to PM (Gallus gallus)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Saccharomyces cerevisiae)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Canis familiaris)


name: Na(+)(out) + propanoate(out) = Na(+)(in) + propanoate(in)


name: p85 associates with both p-Nephrin and CD2AP (Homo sapiens)


name: a sphingoid 1-phosphate + ADP + H(+) => a sphingoid base + ATP


name: LTC4S trimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Mus musculus)


name: Tyrosine is hydroxylated to dopa (Sus scrofa)


name: chloride(out) + creatine(out) + 2 Na(+)(out) = chloride(in) + creatine(in) + 2 Na(+)(in)


name: A + all-trans-3,4-didehydro-13,14-dihydroretinol = AH2 + all-trans-3,4-didehydroretinol


name: H2O + N(2)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2 = (1-deoxy-D-fructos-1-yl)amine + 6-amino-2-oxohexanoate + H2O2


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Drosophila melanogaster)


name: (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2 = (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate


name: Active LTK receptor binds SHC1 (Homo sapiens)


name: (9Z)-octadecenoyl-CoA + a 1-acyl-sn-glycero-3-phospho-L-serine = 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: L-arginyl-[dinitrogen reductase] + NAD(+) => H(+) + N(omega)-alpha-(ADP-D-ribosyl)-L-arginyl-[dinitrogen reductase] + nicotinamide


name: Inactive RAFs bind YWHAB (Plasmodium falciparum)


name: a secondary aliphatic amine + H2O + O2 = a primary amine + an aldehyde + H2O2


name: SETD6 methylates RELA in the NFkB complex (Canis familiaris)


name: MTMR8 binds MTMR9 (Drosophila melanogaster)


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Bos taurus)


name: NADP(+) + nonan-2-one = (3E)-nonen-2-one + H(+) + NADPH


name: Direct Host Cell Membrane Membrane Fusion and Release of SARS-CoV-2 Nucleocapsid (Homo sapiens)


name: HRH1 binds HRH1 inverse agonists (Rattus norvegicus)


name: anthranilate + 2 ATP + L-phenylalanine + S-adenosyl-L-methionine => 2 AMP + cyclopeptine + 2 diphosphate + 2 H(+) + S-adenosyl-L-homocysteine


name: 4 H(+) + narbomycin + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] <=> 2 H2O + novapikromycin + 4 oxidized [2Fe-2S]-[ferredoxin]


name: Dephosphorylation of Lck-pY505 by CD45 (Homo sapiens)


name: 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 17beta,19-dihydroxy-3-oxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase]


name: coenzyme B + methyl-coenzyme M => coenzyme M-coenzyme B heterodisulfide + methane


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Canis familiaris)


name: IAP2:BEN:UEV1A E3 ligase complex auto-ubiquitinates (Drosophila melanogaster)


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: ATP + deamido-NAD(+) + NH4(+) => AMP + diphosphate + H(+) + NAD(+)


name: CYP4F8 19-hydroxylates PGH2 (Xenopus tropicalis)


name: 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 <=> dichlorochromopyrrolate + H(+) + 2 H2O + NH4(+)


name: RAS:GTP binds RAL GDS proteins (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate + H2O + heme b => diphosphate + Fe(II)-heme o


name: (R)-prunasin + H2O <=> D-glucose + mandelonitrile


name: 2 (S)-lactate(in) + prostaglandin F2alpha(out) <=> 2 (S)-lactate(out) + prostaglandin F2alpha(in)


name: H2O + NAD(+) + rifamycin SV para-naphthoquinone carboxamide => NADH + O2 + rifamycin SV


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+)


name: SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)


name: GDP-alpha-D-glucose + phosphate <=> alpha-D-glucose 1-phosphate + GDP + H(+)


name: VDAC1 transports PYR from cytosol to mitochondrial intermembrane space (Plasmodium falciparum)


name: SREBP1A,1C,2:Importin beta-1 dissociates (Mus musculus)


name: citrate(out) + maleate(in) = citrate(in) + maleate(out)


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)


name: Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Sus scrofa)


name: urocanate + H2O => 4-imidazolone-5-propionate (Dictyostelium discoideum)


name: WWOX binds ERBB4s80 (Drosophila melanogaster)


name: (S)-malate + NADP(+) = CO2 + NADPH + pyruvate


name: SULTs transfer (SO4)2- group to 27HCHOL (Sus scrofa)


name: ATP + D-glycero-alpha-D-manno-heptose 7-phosphate <=> ADP + D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + H(+)


name: RHOF GAPs stimulate RHOF GTPase activity (Drosophila melanogaster)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Bos taurus)


name: ent-7alpha-hydroxykaur-16-en-19-oate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => gibberellin A12 aldehyde + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Bos taurus)


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + H2O => (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate


name: [thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Mus musculus)


name: carnosine + S-adenosyl-L-methionine <=> anserine + H(+) + S-adenosyl-L-homocysteine


name: PTB and hnRNPA1 bind FGFR2 pre-mRNA to repress IIIb splicing and promote formation of FGFR2c mRNA (Bos taurus)


name: berkeleyone B + CO2 + H2O + succinate => 2-oxoglutarate + O2 + preaustinoid A1


name: ATM phosphorylates HERC2 (Drosophila melanogaster)


name: ESD dimer hydrolyses S-FGSH to GSH (Mus musculus)


name: RUNX1 binds PRC1 complexes (Homo sapiens)


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)


name: L-ribulose 5-phosphate <=> L-xylulose 5-phosphate


name: 2 ATP + L-proline + L-tryptophan = 2 AMP + brevianamide F + 2 diphosphate + 2 H(+)


name: COX18 inserts nascent MT-CO2 in COX20:TMEM77 (Sus scrofa)


name: Expression of OTX2 in anterior neural plate (Homo sapiens)


name: 3-oxo-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA + NADP(+)


name: MUT isomerises L-MM-CoA to SUCC-CoA (Caenorhabditis elegans)


name: METAP1/2 demethylates GNAT1 (Xenopus tropicalis)


name: NPAS4 binds ARNTL (BMAL1) (Mus musculus)


name: GRKs bind ADRB2:Catecholamine (Bos taurus)


name: (9Z)-heptadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (9Z,12Z)-heptadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Phosphorylation of APC component of the destruction complex (Mus musculus)


name: 4-(dimethylamino)azobenzene + H2O + NADP(+) => 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH


name: [Rab1 protein]-L-serine + CDP-choline <=> [Rab1 protein]-O-phosphocholine-L-serine + CMP + H(+)


name: 17alpha-hydroxyprogesterone + NADPH + O2 = acetate + androst-4-ene-3,17-dione + H2O + NADP(+)


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Canis familiaris)


name: Association of Ku heterodimer with ends of DNA double-strand break (Homo sapiens)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Homo sapiens)


name: A + asnovolin J => AH2 + chermesin D methyl ester


name: UDP-alpha-D-xylose + zeatin => H(+) + O-beta-D-xylosylzeatin + UDP


name: TBK1 or IKBKE forms homodimers (Homo sapiens)


name: The addition of GalNAc to the terminal glucuronate residue forms chondroitin (Rattus norvegicus)


name: L1 and NCAM1 engaged in cis-interaction (Mus musculus)


name: ROBO3.1 expression is stimulated by LHX2,(LHX9) (Homo sapiens)


name: Formation of dehydro-lysinonorleucine cross-links (Gallus gallus)


name: CO2 + H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NADP(+) = (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 3 H(+) + NADPH


name: D-tyrosine + H2O + O2 => 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Homo sapiens)


name: Ubiquitinated DVL is degraded by the proteasome (Dictyostelium discoideum)


name: DAG is metabolized by DAGL to 2-AG (Xenopus tropicalis)


name: H(+) + L-arginyl-[protein] + lactate => H2O + N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein]


name: G alpha (q) in G (q):RGS complex is inactivated (Drosophila melanogaster)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> (-)-astellatene + diphosphate


name: (E)-coniferol + UDP-alpha-D-glucose => 4-O-(beta-D-glucosyl)-(E)-coniferol + H(+) + UDP


name: PTHP is reduced to BH4 by sepiapterin reductase (SPR) (Homo sapiens)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Schizosaccharomyces pombe)


name: CYP26A1,B1 4-hydroxylate atRA (Xenopus tropicalis)


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Rattus norvegicus)


name: ferric triacetylfusarinine C transmembrane transporter activity


name: Phosphorylation of IKK-beta by TAK1 (Mus musculus)


name: Heparin binds PKR (Caenorhabditis elegans)


name: Adenylaye cyclase increases the GTPase activity of G alpha-olf (Bos taurus)


name: Dentin phosphoprotein binds integrin alphaVbeta1 (Homo sapiens)


name: NTPDase4 hydrolyzes nucleoside triphosphates (Xenopus tropicalis)


name: DRD2 antagonist drugs bind to DRD2 (Canis familiaris)


name: (2E,6E,10E)-geranylgeranyl diphosphate => diphosphate + talarodiene


name: 1-octanoylglycerol + H2O => glycerol + H(+) + octanoate


name: VLDLR:PCSK9 binds Clathrin-coated vesicles (Rattus norvegicus)


name: (3S)-versiconol acetate + H2O => (S)-versiconol + acetate + H(+)


name: H(+) + o-quinone methide + peniphenone D <=> penilactone A


name: ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+)


name: Cho transports from the extracellular space to the cytosol (Dictyostelium discoideum)


name: a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + S-adenosyl-L-homocysteine


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine => 3 H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen (Homo sapiens)


name: PTPN1 dephosphorylates PTK6 (Rattus norvegicus)


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Rattus norvegicus)


name: H2O + N-acyl-sn-glycero-3-phosphoethanolamine <=> an N-acylethanolamine + H(+) + sn-glycerol 3-phosphate


name: Digestion of branched starch (amylopectin) by extracellular amylase (Gallus gallus)


name: a menaquinone + H2O + sulfite <=> a menaquinol + sulfate


name: Assembly of hexameric IL-6 receptor (Bos taurus)


name: 2 e(-) + 2 H(+) + 2 nitric oxide => H2O + nitrous oxide


name: (R)-tembetarine + H(+) + S-adenosyl-L-homocysteine => (R)-reticuline + S-adenosyl-L-methionine


name: CoA + O-3-methylbutanoyl-(R)-carnitine => (R)-carnitine + 3-methylbutanoyl-CoA


name: N-terminal N-methyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N-dimethyl-glycyl-L-lysyl-L-glutamyl-[protein] + S-adenosyl-L-homocysteine


name: CHRM4 binds CHRM4 antagonists (Xenopus tropicalis)


name: H2O + N-acetyl-L-glutamine <=> acetate + L-glutamine


name: H2O + L-isoleucine + NAD(+) = (S)-3-methyl-2-oxopentanoate + H(+) + NADH + NH4(+)


name: 2-oxoglutaramate + L-phenylalanine => 3-phenylpyruvate + L-glutamine


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Caenorhabditis elegans)


name: CCNG1 recruits PP2A-PPP2R5C to MDM2 (Rattus norvegicus)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Canis familiaris)


name: 9-cis-retinol + a fatty acyl-CoA = 9-cis-retinyl ester + CoA


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Sus scrofa)


name: 3-octadecanoyl-sn-glycero-1-phospho-(3'-octadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol) => 2 3-octadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol)


name: TRAF2:cIAP1/2 complex binds FN14:TWEAK (Homo sapiens)


name: SLITs bind keratan sulfate (Drosophila melanogaster)


name: FPRL2 receptor binds a wide range of ligands (Mus musculus)


name: 3-oxochol-4-en-22-oyl-CoA + H(+) + NADH + O2 <=> 9alpha-hydroxy-3-oxochol-4-en-22-oyl-CoA + H2O + NAD(+)


name: HFE binds TFRC dimer (Rattus norvegicus)


name: (S)-malate(in) + sulfate(out) => (S)-malate(out) + sulfate(in)


name: Inactivation of APC/C via CDC20 sequestration (Dictyostelium discoideum)


name: RAC1,RAC2,RHOG activate PI3K (Rattus norvegicus)


name: H2O + sn-glycero-3-phospho-L-serine => H(+) + L-serine + sn-glycerol 3-phosphate


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Rattus norvegicus)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man9GlcNAc2 to produce Man5GlcNAc2 (Bos taurus)


name: a ubiquinone + D-glucose = a ubiquinol + D-glucono-1,5-lactone


name: "quinoprotein glucose dehydrogenase (PQQ, quinone)"


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Schizosaccharomyces pombe)


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Danio rerio)


name: guanosine(2270) in 21S rRNA + S-adenosyl-L-methionine => 2'-O-methylguanosine(2270) in 21S rRNA + H(+) + S-adenosyl-L-homocysteine


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O => 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: IRAK4 is activated by autophosphorylation (Rattus norvegicus)


name: CDP-glycerol + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate = 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: "teichoic acid glycerol-phosphate primase"


name: Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)


name: isorhamnetin + S-adenosyl-L-methionine <=> H(+) + rhamnacene + S-adenosyl-L-homocysteine


name: AKR1B1 reduces Glc to D-sorbitol (Mus musculus)


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Sus scrofa)


name: 2-oxo-dADP + H2O = 2-oxo-dAMP + H(+) + phosphate


name: [6)-beta-D-fructofuranosyl-(2->](n) alpha-D-glucopyranoside + sucrose <=> [6)-beta-D-fructofuranosyl-(2->](n+1) alpha-D-glucopyranoside + D-glucose


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Xenopus tropicalis)


name: ADP + H(+) + O-phosphoviomycin => ATP + viomycin


name: Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)


name: EHD proteins interact with Rabenosyn-5 (Mus musculus)


name: a long-chain fatty aldehyde + holo-[ACP] + NADP(+) = a long-chain fatty acyl-[ACP] + H(+) + NADPH


name: CSN polymer binds CaPO4 (Rattus norvegicus)


name: RDH13 reduces atRAL to atROL (Xenopus tropicalis)


name: Hydroxyl radicals oxidize ST to 2,3-DHBA (Homo sapiens)


name: p-DAPP1 (p-BAM32) binds PLCG2 (Mus musculus)


name: (3S)-hydroxyhexanoyl-CoA <=> (2E)-hexenoyl-CoA + H2O


name: FAM83B, (FAM83A, FAM83D) bind EGFR (Canis familiaris)


name: Fe(2+)(out) + 2 hydrogencarbonate(out) <=> Fe(2+)(in) + 2 hydrogencarbonate(in)


name: TFPI + TF:F7a + factor Xa -> TFPI:TF:F7a:factor Xa (Sus scrofa)


name: SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region (Canis familiaris)


name: (1R,4R,5S)-acoradiene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> 2,6,9-trimethyl-13-oxatetracyclo[6.3.1.1(6,9).0(1,5)]tridecane carbocation + H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Schizosaccharomyces pombe)


name: HPN heterodimer cleaves pro-HGF to form HGF dimer (Mus musculus)


name: Decarboxylation of 5-hydroxytryptophan forms serotonin (Rattus norvegicus)


name: CYP17A1 17-hydroxylates PREG (Sus scrofa)


name: adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methyladenosine(1067) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine


name: a 2-(omega-methylsulfanyl)alkylmaleate + H2O => a 2-(omega-methylsulfanyl)alkylmalate


name: a neolactoside nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose <=> a neolactoside III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+)


name: 2 ATP + L-proline + L-tryptophan + NADPH = (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + 2 AMP + 2 diphosphate + H(+) + H2O + NADP(+)


name: H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine <=> (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG2 (Drosophila melanogaster)


name: ub UBXN7 is degraded by the 26S proteasome (Danio rerio)


name: (2E)-dodecenoyl-CoA + H(+) + NADH = dodecanoyl-CoA + NAD(+)


name: 6alpha-hydroxycastasterone + O2 + reduced [NADPH--hemoprotein reductase] <=> castasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Sus scrofa)


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Xenopus tropicalis)


name: "diadenosine hexaphosphate hydrolase (AMP-forming)"


name: CoA + L-2-acetamido-6-oxoheptanedioate => (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O


name: D-glucose + DIMBOA => DIMBOA beta-D-glucoside + H2O


name: 3'-phosphoadenylyl sulfate + UDP-N-acetyl-alpha-D-galactosamine 4-sulfate = adenosine 3',5'-bisphosphate + H(+) + UDP-N-acetyl-alpha-D-galactosamine 4,6-bissulfate


name: HuR binds mRNAs in the nucleus (Bos taurus)


name: Phosphorylation of EGFR by SRC kinase (Bos taurus)


name: Exocytosis of secretory granule lumen proteins (Saccharomyces cerevisiae)


name: AGO2 cleaves passenger strand of duplex siRNA (Schizosaccharomyces pombe)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Mus musculus)


name: H2O + L-glutamate 5-semialdehyde + NADP(+) = 2 H(+) + L-glutamate + NADPH


name: H(+) + O2 + protoviolaceinate <=> CO2 + H2O + proviolacein


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Mus musculus)


name: [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + H2O = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + H(+) + methanol


name: di-trans,nona-cis-dodecaprenyl phosphate + UDP-alpha-D-galacturonate = beta-D-galacturonosyl di-trans,nona-cis-dodecaprenyl phosphate + UDP


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Homo sapiens)


name: dihydrocarveol + NAD(+) => dihydrocarvone + H(+) + NADH


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Homo sapiens)


name: 2 H(+) + H2O + thiocyanate <=> carbonyl sulfide + NH4(+)


name: MAP2Ks phosphorylate MAPKs (Rattus norvegicus)


name: L-alanine + pyridoxal => pyridoxamine + pyruvate


name: AFG3L2:SPG7 degrades SMDT1 (EMRE) (Caenorhabditis elegans)


name: (+)-valencene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => (+)-nootkatone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Canis familiaris)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Schizosaccharomyces pombe)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] => 15alpha-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PSGs bind proteoglycans and TGF-beta1 (Xenopus tropicalis)


name: Active LTK binds GRB2:TNK2 (Mus musculus)


name: (2Z,6E)-farnesyl diphosphate = (E)-alpha-bisabolene + diphosphate


name: 4-prenylphlorisobutanophenone + dimethylallyl diphosphate <=> deoxycohumulone + diphosphate


name: Equilibrative transport (import) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Drosophila melanogaster)


name: (2S,3R,11S)-aszonalenin + diphosphate => (S)-benzodiazepinedione + dimethylallyl diphosphate


name: acarbose 7(IV)-phosphate + ADP + H(+) => acarbose + ATP


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O <=> ADP-alpha-D-ribose 1''-phosphate + H(+)


name: SLC25A18,22 import L-Glu, H+ (Dictyostelium discoideum)


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Caenorhabditis elegans)


name: L3MBTL1 binds TP53 monomethylated on K382 (Drosophila melanogaster)


name: KAT5 acetylates ATM at DNA DSBs (Mus musculus)


name: Recruitment of AP-2 complex and clathrin (Sus scrofa)


name: a 7(1),7(1)-dihydroxybacteriochlorophyllide d <=> a bacteriochlorophyllide f + H2O


name: Formation of MHC II alpha beta heterodimer (Homo sapiens)


name: Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Danio rerio)


name: Catabolism of Noradrenaline (Rattus norvegicus)


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Sus scrofa)


name: VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization (Gallus gallus)


name: dimethylsulfonioacetate + L-homocysteine <=> (methylsulfanyl)acetate + H(+) + L-methionine


name: CYP7B1 7-hydroxylates 25OH-CHOL (Sus scrofa)


name: decanoate + O2 + reduced [NADPH--hemoprotein reductase] = 10-hydroxydecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADP + biotin(out) + H(+) + phosphate => ATP + biotin(in) + H2O


name: L-glutamate(out) + 2 Na(+)(out) => L-glutamate(in) + 2 Na(+)(in)


name: TGN-lysosomal vesicle coat assembly (Bos taurus)


name: TMT transfers CH3 from AdoMet to BME (Homo sapiens)


name: p-S54,92,203-BRF1 binds 14-3-3 (Homo sapiens)


name: an inositol-1-phosphodihydroceramide + GDP-alpha-D-mannose = an alpha-D-mannosylinositol-1-phosphodihydroceramide + GDP + H(+)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Bos taurus)


name: (9Z)-hexadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine => 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: ADP + gamma-L-glutamyl-L-glutamyl-[protein] + H(+) + phosphate => ATP + L-glutamate + L-glutamyl-[protein]


name: Caspase-mediated cleavage of TJP1 (Mus musculus)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Canis familiaris)


name: Furin cleaves pro-protein S to protein S (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O => (9Z)-octadecenoate + 1-hexadecanoyl-3-octadecanoyl-sn-glycerol + H(+)


name: Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Sus scrofa)


name: ATP binding to HSP90 triggers conformation change (Homo sapiens)


name: L-cysteine + O-acetyl-L-homoserine = acetate + H(+) + L,L-cystathionine


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: AcK-NFE2L2 and MAFK bind NQO1 gene (Homo sapiens)


name: 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA => benzoyl-CoA + 2 H(+) + 3 malonyl-CoA


name: a uridine in rRNA = a pseudouridine in rRNA


name: acetyl-CoA + N(6)-methyl-L-lysyl-[histone] <=> CoA + H(+) + N(6)-acetyl-N(6)-methyl-L-lysyl-[histone]


name: SEPHS2 phosphorylates H2Se to form SELP (Caenorhabditis elegans)


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Mus musculus)


name: MDM2 forms homo- or heterodimers (Xenopus tropicalis)


name: VAV exchanges GTP for GDP on RAC1, activating it (Homo sapiens)


name: (S)-lactate(in) + urate(out) <=> (S)-lactate(out) + urate(in)


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Danio rerio)


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Mus musculus)


name: Collagen type IX binds integrin alpha11beta1 (Canis familiaris)


name: an acyl-CoA + sn-glycerol 3-phosphate <=> a 2-acyl-sn-glycerol 3-phosphate + CoA


name: The ABCC family mediates organic anion transport (Gallus gallus)


name: ATP + N-acetyl-D-muramate => ADP + H(+) + N-acetyl-alpha-D-muramate 1-phosphate


name: SLC52A1,2,3 transport RIB from extracellular region to cytosol (Mus musculus)


name: DAG is metabolized by DAGL to 2-AG (Homo sapiens)


name: a (2R,3R)-dihydroflavonol + CO2 + succinate => 2-oxoglutarate + a (2S)-flavan-4-one + O2


name: cholate + deoxycholoyl-CoA <=> choloyl-CoA + deoxycholate


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Bos taurus)


name: 4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine <=> 4-(3-methylbut-2-enyl)-L-abrine + H(+) + S-adenosyl-L-homocysteine


name: 2 H2O + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADP(+) => H(+) + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + NADPH + O2


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Homo sapiens)


name: Phosphorylation and activation of Ezrin (Caenorhabditis elegans)


name: CO2 + propanoyl-CoA => (S)-methylmalonyl-CoA + H(+)


name: Formation of the outer ring of the 20S core particle (Homo sapiens)


name: ADP + H(+) + L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) => ADP-L-glycero-beta-D-manno-heptose + L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: (2E,6E)-farnesyl diphosphate + 3,5-dimethylorsellinate => (3R)-3-farnesyl-6-hydroxy-2,3,5-trimethyl-4-oxocyclohexa-1,5-diene-1-carboxylate + diphosphate + H(+)


name: PGM2:Mg2+ isomerises R1P to R5P (Caenorhabditis elegans)


name: 3,4-dihydroxypyridine + O-acetyl-L-serine => 3-(3,4-dihydroxypyridin-1-yl)-L-alanine + acetate + H(+)


name: ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA (Xenopus tropicalis)


name: hydroxyurea + O-acetyl-L-serine = acetate + H(+) + O-ureido-L-serine


name: tRNA-guanosine(34) queuine transglycosylase activity


name: H2O2 + rifamycin O => 2 H(+) + O2 + rifamycin B


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Homo sapiens)


name: 1,2-diacyl-3-O-[alpha-D-glucosyl-(1-> 2)-alpha-D-glucosyl]-sn-glycerol + H(+) + UDP => a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-glucose


name: DAG activation of TRPC channels (Gallus gallus)


name: lithocholoyl-CoA + ursodeoxycholate => lithocholate + ursodeoxycholoyl-CoA


name: Interaction of integrin alphaDbeta2 with fibrin (Mus musculus)


name: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Sus scrofa)


name: 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Ser-[protein] + CMP-N-acetyl-beta-neuraminate <=> 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-Ser-[protein] + CMP + H(+)


name: formaldehyde + L-alanine => 2-methyl-L-serine


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)


name: octadecanoyl-CoA + sphinga-4E,14Z-dienine = CoA + H(+) + N-octadecanoyl-sphinga-4E,14Z-dienine


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O => 6-phospho-D-gluconate


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) => 4,5-dihydroxyphthalate + H(+) + NADH


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O <=> H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: 1-O-alkyl-2-acyl-sn-glycerol + an acyl-CoA = 1-O-alkyl-2,3-diacyl-sn-glycerol + CoA


name: (2E)-decenoyl-[ACP] + H(+) + NADPH <=> decanoyl-[ACP] + NADP(+)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + all-trans-retinol--[retinol-binding protein] = a 2-acyl-sn-glycero-3-phosphocholine + an all-trans-retinyl ester + apo--[retinol-binding protein]


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Xenopus tropicalis)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Sus scrofa)


name: CHEK2 phosphorylates BRCA1 (Mus musculus)


name: NADP(+) + propanal = acrolein + H(+) + NADPH


name: The bound receptor dimerizes (Canis familiaris)


name: 5-hydroxyisourate + H2O <=> 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)


name: ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine


name: ATP + L-threonyl-[Goodpasture antigen-binding protein] = ADP + H(+) + O-phospho-L-threonyl-[Goodpasture antigen-binding protein]


name: a globoside Gb3Cer (d18:1(4E)) + H2O => a fatty acid + a lysoGb3(d18:1(4E))


name: (2E,6E)-farnesyl diphosphate => alpha-copaene + diphosphate


name: pro-HD5 is cleaved by trypsin (Rattus norvegicus)


name: Dimethyl fumarate modifies Cys191 in GSDMD (Homo sapiens)


name: a 3beta-hydroxysteroid + a triacylglycerol <=> a 1,3-diacylglycerol + a 3beta-hydroxysteroid ester


name: RHOF auto-activates (Schizosaccharomyces pombe)


name: alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 UDP-alpha-D-galactofuranose <=> beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 2 H(+) + 2 UDP


name: adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H2O + 4 L-glutamine = adenosylcob(III)yrate + 4 ADP + 4 H(+) + 4 L-glutamate + 4 phosphate


name: "adenosylcobyric acid synthase (glutamine-hydrolyzing)"


name: 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate => (9Z,12Z)-octadecadienoate + 1-hexadecanoylglycerone 3-phosphate


name: (2R)-3-phosphoglycerate + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+)


name: PDPK1 binds PIP3 (Saccharomyces cerevisiae)


name: (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH => 2-dehydro-3-deoxy-D-gluconate + NADP(+)


name: 2-oxoglutarate + an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + O2 = a 2'-deoxycytidine in double-stranded DNA + CO2 + formaldehyde + H(+) + succinate


name: dimethyl sulfide + H2O + menaquinone-8 => dimethyl sulfoxide + menaquinol-8


name: E1 mediated ubiquitin activation (Sus scrofa)


name: 3,3',5-triiodo-L-thyronine(out) + L-phenylalanine(in) <=> 3,3',5-triiodo-L-thyronine(in) + L-phenylalanine(out)


name: 2-O-hexadecanoyl-alpha,alpha-trehalose + CoA => alpha,alpha-trehalose + hexadecanoyl-CoA


name: 2-oxoglutarate + H(+) + NADH + NH4(+) => H2O + L-glutamate + NAD(+)


name: (2R,3S)-piscidate + (E)-feruloyl-CoA => cimicifugate E + CoA


name: beta-glucan transmembrane transporter activity


name: Dimerized Phospho-IRF3 is Transported To The Nucleus (Gallus gallus)


name: PARG dePARylates PARP1,PARP2 (Dictyostelium discoideum)


name: ATP + butanoyl-CoA + hydrogencarbonate <=> (2R)-ethylmalonyl-CoA + ADP + H(+) + phosphate


name: 17beta-estradiol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate => 17beta-estradiol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) => 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Association of Golgi  transport vesicles with microtubules (Canis familiaris)


name: Endocytosis of TGFBR3:ARRB complex (Drosophila melanogaster)


name: SLC25A12,13 exchange L-Glu and L-Asp (Dictyostelium discoideum)


name: 4-methoxybenzoate + ATP + H(+) + NADPH = 4-methoxybenzaldehyde + AMP + diphosphate + NADP(+)


name: L-asparagine(in) + L-glutamine(out) + Na(+)(in) => L-asparagine(out) + L-glutamine(in) + Na(+)(out)


name: Recruitment of BCAR1 to PTK2 complex (Homo sapiens)


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Bos taurus)


name: GNRHR binds GNRHR peptide antagonists (Bos taurus)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Xenopus tropicalis)


name: ADP + H(+) + methionine(in) + phosphate => ATP + H2O + methionine(out)


name: a 2,3-diacyl-sn-glycerol + H2O <=> a 3-acyl-sn-glycerol + a fatty acid + H(+)


name: ATP4A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)


name: RAC1 and CDC42 activate PAK2 (Rattus norvegicus)


name: ADO oxidises 2AET to HTAU (Xenopus tropicalis)


name: (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O => resolvin E1


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + H2O = 1-O-alkyl-2-acyl-sn-glycerol + a fatty acid + H(+)


name: Keratin type I/type II heterodimers form tetramers (Gallus gallus)


name: Formation of the 19S regulatory particle precursor (Rattus norvegicus)


name: USP21 deubiquitinates RIPK1,DDX58 (Bos taurus)


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Sus scrofa)


name: H2O + P(1),P(6)-bis(5'-adenosyl) hexaphosphate = adenosine 5'-pentaphosphate + AMP + 2 H(+)


name: ethanol + hexanoyl-CoA => CoA + ethyl hexanoate


name: Ubiquitination of IKBKG by TRAF6 (Sus scrofa)


name: SGK phosphorylates SRF (Dictyostelium discoideum)


name: PDCL promotes G-protein beta 5 folding (Drosophila melanogaster)


name: ATM phosphorylates MDC1 (Canis familiaris)


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Canis familiaris)


name: Factor Xa inhibitors binds Xa (Rattus norvegicus)


name: acetate + eugenol + NADP(+) => (E)-coniferyl acetate + NADPH


name: 4,4'-diaponeurosporenoate + 2 H(+) + NADH => 4,4'-diaponeurosporenal + H2O + NAD(+)


name: IQGAP1 binds CLIP1 and microtubules (Homo sapiens)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + octadecanoate => (R)-2-hydroxyoctadecanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Gallus gallus)


name: anthranilate + 3 H(+) + NADPH + O2 = catechol + CO2 + NADP(+) + NH4(+)


name: JAK2 is phosphorylated, activated (Gallus gallus)


name: ent-copalyl diphosphate => diphosphate + ent-beyerene


name: SGT1:HSP90 binds inactive NLRP3 (Rattus norvegicus)


name: acryloyl-CoA + H2O => 3-hydroxypropanoyl-CoA


name: TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Sus scrofa)


name: [protein]-disulfide + 2 glutathione => [protein]-dithiol + glutathione disulfide


name: hexan-1-ol + NADP(+) = H(+) + hexanal + NADPH


name: nsp3 binds to nsp7-8 and nsp12-16 (Homo sapiens)


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Xenopus tropicalis)


name: histone H2AR3 methyltransferase activity


name: 2-dehydro-D-glucose + H2O2 + L-glutamate => H2O + N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-glutamate + O2


name: GSTO dimers reduce DeHA to AscH- (Xenopus tropicalis)


name: (20S)-ginsenoside Rh2 + H(+) + UDP => (20S)-protopanaxadiol + UDP-alpha-D-glucose


name: ADP + thiamine diphosphate = AMP + thiamine triphosphate


name: 2-oxoglutarate + O2 + octadecanoyl-CoA => 2-hydroxyoctadecanoyl-CoA + CO2 + succinate


name: Syndecans 1, 2, 4, (3) bind FGF2 (Homo sapiens)


name: amicoumacin A + phosphate => amicoumacin A 2-phosphate + H2O


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Drosophila melanogaster)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate <=> 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate


name: androsterone + H(+) + NADH => 5alpha-androstane-3alpha,17beta-diol + NAD(+)


name: Free APC/C phosphorylated by Plk1 (Canis familiaris)


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Mus musculus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA => 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA


name: Mitochondrial FPGS-1 transforms THF to THFPG (Saccharomyces cerevisiae)


name: STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Bos taurus)


name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Mus musculus)


name: decanoyl-CoA + FAD + H(+) => (2E)-decenoyl-CoA + FADH2


name: RHOG binds effectors at the ER membrane (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate => 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-adenosine in mRNA + H2O => a 5'-end phospho-adenosine in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: Loading of dopamine into synaptic veiscles (Schizosaccharomyces pombe)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA <=> 3-oxochol-4,6-dien-24-oyl-CoA + H2O


name: Nuclear DUSPs dephosphorylate MAPKs (Plasmodium falciparum)


name: 1-deoxypentalenate + 2-oxoglutarate + O2 = 1-deoxy-11beta-hydroxypentalenate + CO2 + succinate


name: H2O + sepiapterin <=> 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+)


name: ATP + holo-[peptidyl-carrier protein] + L-tryptophan = AMP + diphosphate + L-tryptophyl-[peptidyl-carrier protein]


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(in) + ATP + H2O = (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(out) + ADP + H(+) + phosphate


name: COQ3 methylates DHDB (Saccharomyces cerevisiae)


name: CD19 Signalosome phosphorylates PI(4,5)P2 forming PI(3,4,5)P3 (Drosophila melanogaster)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Saccharomyces cerevisiae)


name: a (2R)-2-hydroxycarboxylate + NAD(+) => a 2-oxocarboxylate + H(+) + NADH


name: G13 activation by TP receptor (Caenorhabditis elegans)


name: ATP + H2O + leukotriene C4(out) = ADP + H(+) + leukotriene C4(in) + phosphate


name: 2'-O-methylisoliquiritigenin + H(+) + S-adenosyl-L-homocysteine => isoliquiritigenin + S-adenosyl-L-methionine


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Drosophila melanogaster)


name: C5L2 anaphylatoxin chemotactic receptor binding


name: CMAS transfers CMP from CTP to Neu5Ac, forming CMP-Neu5Ac (Mus musculus)


name: precorrin-4 + S-adenosyl-L-methionine => precorrin-5 + S-adenosyl-L-homocysteine


name: APRT catalyzes the conversion of adenine to AMP (Xenopus tropicalis)


name: PDE6 hydrolyses cGMP to GMP (Sus scrofa)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Xenopus tropicalis)


name: delta-guaiene + diphosphate => (2E,6E)-farnesyl diphosphate


name: NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Homo sapiens)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)


name: AUF1:mRNA complex is destroyed (Gallus gallus)


name: RAD51B:RAD51C binds single-stranded DNA (Homo sapiens)


name: RHOT1 binds effectors at the mitochondrial outer membrane (Mus musculus)


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Xenopus tropicalis)


name: ARFGAPs stimulate ARF GTPase activity (Mus musculus)


name: adenosine 3',5'-bisphosphate(out) + FAD(in) => adenosine 3',5'-bisphosphate(in) + FAD(out)


name: D-galactose + NADP(+) = D-galactono-1,5-lactone + H(+) + NADPH


name: Furin cleaves pro-protein S to protein S (Danio rerio)


name: 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H(+) => 1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O


name: (2S,4R)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine => (2R)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi (Xenopus tropicalis)


name: cortalcerone + H2O => 2-dehydro-D-glucose


name: 4-hydroxyestrone + O2 => (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+)


name: 7-cyano-7-deazaguanine + guanosine(15) in tRNA <=> 7-cyano-7-carbaguanosine(15) in tRNA + guanine


name: Phosphorylated BORA binds SCF-beta-TrCp1/2 (Caenorhabditis elegans)


name: (2E)-dodecenoyl-CoA + H2O => (2E)-dodecenoate + CoA + H(+)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Danio rerio)


name: a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(+) + UDP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + UDP-N-acetyl-alpha-D-glucosamine


name: Interaction of GRB2:SOS complex with p-SHC1 (Bos taurus)


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Xenopus tropicalis)


name: (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O2 => (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H(+)


name: L-glutamate + succinate => H2O + N-succinyl-L-glutamate


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Bos taurus)


name: 2 Fe(III)-[cytochrome c3] + hydrogen sulfide + sulfite <=> 2 Fe(II)-[cytochrome c3] + thiosulfate


name: aclacinomycin A + O2 <=> aclacinomycin Y + H2O2


name: QPRT transfers PRIB to QUIN to form NAMN (Xenopus tropicalis)


name: STAT5-dependent PIM1 gene expression downstream of FLT3 ITD and fusion mutants (Homo sapiens)


name: ADP-Ribosylation of HNP-1 (Homo sapiens)


name: CHRM2,4 bind acetylcholine (Caenorhabditis elegans)


name: Tenascins C, R, (X, N) bind lecticans (Canis familiaris)


name: STON2 is neddylated (Saccharomyces cerevisiae)


name: (9Z)-octadecenoate + H(+) + N-eicosanoyl-sn-glycero-3-phosphoethanolamine => H2O + N-eicosanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: guanosine(966) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine


name: Dimerization of KIT upon SCF binding (Gallus gallus)


name: H2O2 + urate => 6,8-dihydroxypurine + H2O + O2


name: (S)-scoulerine + S-adenosyl-L-methionine => (S)-cis-N-methylscoulerine + S-adenosyl-L-homocysteine


name: PLA2G15 hydrolyses LPC to GPCho and LCFA(-) (Xenopus tropicalis)


name: Internalization of ubiquitinated FLT3 (Homo sapiens)


name: n H(+)(out) + serotonin(in) => n H(+)(in) + serotonin(out)


name: SCUBE1, SCUBE3 oligomerize (Plasmodium falciparum)


name: H(+) + methylglyoxal + NADH => hydroxyacetone + NAD(+)


name: LNK binds to p-KIT and inhibit downstream signaling (Gallus gallus)


name: Reduction of disulphide bonds in MHC II antigens (Homo sapiens)


name: 9-hydroxy-(10E,12Z)-octadecadienoate + A + H2O => (9Z,12Z)-octadecadienoate + AH2 + O2


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Dictyostelium discoideum)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Drosophila melanogaster)


name: 15,9'-di-cis-phytofluene + plastoquinone-9 <=> 9,9',15-tri-cis-zeta-carotene + plastoquinol-9


name: ethanolamine + H2O + O2 = glycolaldehyde + H2O2 + NH4(+)


name: IDH3 complex decarboxylates isocitrate (Saccharomyces cerevisiae)


name: 5-(9Z-octadecenoyloxy)-octadecanoate + H2O <=> (9Z)-octadecenoate + 5-hydroxy-octadecanoate + H(+)


name: PTPN7 dephosphorylates p-T,Y-MAPKs (Saccharomyces cerevisiae)


name: ATP + geranoyl-CoA + hydrogencarbonate <=> 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + H(+) + phosphate


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Gallus gallus)


name: ADP(in) + dAMP(out) + H(+)(in) => ADP(out) + dAMP(in) + H(+)(out)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 => 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O


name: LIG1 binds POLB at long-patch BER site (Bos taurus)


name: ST3GAL5 transfers NeuNAc to ceramides (Mus musculus)


name: BAMBI interferes with the interaction of type I receptor with type II receptor (Homo sapiens)


name: MAP2K1 phosphorylates MAPK3 (Caenorhabditis elegans)


name: H2O + L-tryptophan + NADP(+) => H(+) + indole-3-pyruvate + NADPH + NH4(+)


name: L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine = 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine


name: (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Activation of RAC1 by VAV (Canis familiaris)


name: L-lysine + NAD(+) <=> 2 H(+) + L-1-piperideine-6-carboxylate + NADH + NH4(+)


name: C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+) => 2 (S)-methylmalonyl-CoA + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Schizosaccharomyces pombe)


name: pseudouridine(55) in tRNA => uridine(55) in tRNA


name: 4-hydroxyestrone + S-adenosyl-L-methionine <=> 4-methoxyestrone + H(+) + S-adenosyl-L-homocysteine


name: Glycosylation and Folding of HA (Homo sapiens)


name: SOAT can transport taurolithocholate-3-sulphate (Rattus norvegicus)


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Homo sapiens)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Rattus norvegicus)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Sus scrofa)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Dictyostelium discoideum)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Saccharomyces cerevisiae)


name: apo-[BtrI ACP] + CoA <=> adenosine 3',5'-bisphosphate + H(+) + holo-[BtrI ACP]


name: SLC16A10-mediated uptake of aromatic amino acids (Gallus gallus)


name: P2Y2 receptor binds ATP and UTP (Canis familiaris)


name: SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Dictyostelium discoideum)


name: [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity


name: GTSE1 promotes translocation of TP53 to the cytosol (Danio rerio)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Bos taurus)


name: acetyl-CoA + UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine = CoA + H(+) + UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose


name: BAR domain proteins recruit dynamin (Caenorhabditis elegans)


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Danio rerio)


name: Oxytocin receptor bind oxytocin (Mus musculus)


name: REG3A binds bacterial phospholipids (Xenopus tropicalis)


name: SFTPB binds itself (Dictyostelium discoideum)


name: 1-hexadecanoylglycerol + H2O <=> glycerol + H(+) + hexadecanoate


name: H(+) + N-methyltyramine + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + tyramine


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Bos taurus)


name: benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Homo sapiens)


name: histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen (Homo sapiens)


name: [TtuB sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate => [TtuB sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+)


name: RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex (Homo sapiens)


name: Separation of elongating transcript from template (Gallus gallus)


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Drosophila melanogaster)


name: CaMKK autophosphorylates in the nucleus (Schizosaccharomyces pombe)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] <=> 8-epi-inunolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: Gi,Go Heterotrimeric G-protein complex dissociates (Rattus norvegicus)


name: Fgr may phosphorylate p38 MAPK (Sus scrofa)


name: FAS-mediated dimerization of procaspase-8 (Rattus norvegicus)


name: MMACHC dealkylates RCbl (Xenopus tropicalis)


name: DUOX1,2 reduce O2 to H2O2 (Xenopus tropicalis)


name: H2O + N(epsilon)-(5'-guanylyl)-N(alpha)-acetyl-L-lysine methyl ester = GMP + N(alpha)-acetyl-L-lysine methyl ester


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-hexacosanoyl-(4R)-hydroxysphinganine + O2 <=> 2 Fe(III)-[cytochrome b5] + H2O + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: acetoacetyl-CoA + acetyl-CoA + H2O <=> (3S)-hydroxy-3-methylglutaryl-CoA + CoA + H(+)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Xenopus tropicalis)


name: CBL monoubiquitinates activated MET (Homo sapiens)


name: estrone 3-sulfate(out) + hydrogencarbonate(in) <=> estrone 3-sulfate(in) + hydrogencarbonate(out)


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Mus musculus)


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Canis familiaris)


name: 3-hydroxypyruvate + L-asparagine => 2-oxosuccinamate + L-serine


name: Phosphorylation of CRMPs by GSK3beta (Gallus gallus)