name: ATP + D-ribose 5-phosphate = ADP + alpha-D-ribose 1,5-bisphosphate + H(+)


name: SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Rattus norvegicus)


name: PAO:FAD oxidises NASPM to PTCN (Rattus norvegicus)


name: chromatin-nuclear membrane anchor activity


name: beta-methylglutaconyl-CoA + H2O <=> beta-hydroxy-beta-methylglutaryl-CoA (Caenorhabditis elegans)


name: eupatolide + H2O => 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+)


name: CALCR binds gepants (Caenorhabditis elegans)


name: POMP binds the 20S core particle outer ring (Drosophila melanogaster)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Schizosaccharomyces pombe)


name: dodecanamide + glyoxylate => N-dodecanoyl-(2S)-hydroxyglycine


name: RHAG transports CO2 from cytosol to extracellular region (Gallus gallus)


name: ATP + keto-D-tagatose => ADP + H(+) + keto-D-tagatose 6-phosphate


name: Activation of Ca permeable AMPA receptors (Danio rerio)


name: H(+) + malonyl-CoA + octacosanoyl-CoA <=> 3-oxo-triacontanoyl-CoA + CO2 + CoA


name: 3 A + phytyl diphosphate = (2E,6E,10E)-geranylgeranyl diphosphate + 3 AH2


name: benzoyl-CoA + glycine <=> CoA + H(+) + N-benzoylglycine


name: (2Z,6Z)-farnesyl diphosphate => diphosphate + gamma-curcumene


name: Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Rattus norvegicus)


name: 2 A + all-trans-4,4'-diapolycopene-4,4'-dial + 2 H2O <=> 2 AH2 + all-trans-4,4'-diapolycopene-4,4'-dioate + 2 H(+)


name: mycinamicin VI 2''-O-methyltransferase activity


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Rattus norvegicus)


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Danio rerio)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Xenopus tropicalis)


name: Arachidonate is hydroxylated to 16-HETE by CYP(1) (Danio rerio)


name: 17beta-estradiol + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 19-oxotestosterone + O2 + reduced [NADPH--hemoprotein reductase]


name: AFG3L2 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: Activated FGFR3:p-FRS bind to PPTN11 (Homo sapiens)


name: ent-copalyl diphosphate => diphosphate + ent-cassa-12,15-diene


name: 5-methyl-1-naphthoate + H(+) + NADPH + O2 <=> 3-hydroxy-5-methyl-1-naphthoate + H2O + NADP(+)


name: H(+)(in) + sulfate(in) <=> H(+)(out) + sulfate(out)


name: DIT and MIT combine to form triiodothyronine (Dictyostelium discoideum)


name: 2-oxoglutarate + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + O2 => CO2 + formaldehyde + N(omega)-methyl-L-arginyl-[protein] + succinate


name: AKR1B15 reduces EST17b to E1 (Xenopus tropicalis)


name: Autoglucosylation of GYG1 complexed with GYS1-b (Saccharomyces cerevisiae)


name: 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate <=> dihydroxyacetone phosphate + L-aspartate 4-semialdehyde


name: a guanosine in 21S rRNA + S-adenosyl-L-methionine = a 2'-O-methylguanosine in 21S rRNA + H(+) + S-adenosyl-L-homocysteine


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> 1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CDP-choline <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ALOX5 oxidises 5(S)-Hp-18(S)-HEPE to 5S,6S-epoxy-18(S)-HEPE (Mus musculus)


name: PSAP gets cleaved (Dictyostelium discoideum)


name: (S)-lactaldehyde + NADP(+) = H(+) + methylglyoxal + NADPH


name: 2-methylpropan-1-amine + H2O + NADP(+) => 2-methylpropanal + H(+) + NADPH + NH4(+)


name: H(+)(out) + homoserine lactone(in) = H(+)(in) + homoserine lactone(out)


name: FMN + H(+) + oxidized coenzyme F420-0 <=> dehydro coenzyme F420-0 + FMNH2


name: CTP + formate + H(+) => CO2 + dCTP + H2O


name: Phosphorylation of nephrin by FYN (Canis familiaris)


name: a globoside Gb3Cer + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside Gb4Cer + H(+) + UDP


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Mus musculus)


name: acetyl-CoA + putrescine <=> CoA + H(+) + N-acetylputrescine


name: O2 + tetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O2


name: FADH2-C4alpha-hydroperoxide + NADP(+) => FAD + 2 H(+) + NADPH + O2


name: NCOA2(869-1464) binds KAT6A(1-1118) (Drosophila melanogaster)


name: (R)-2-hydroxy-4-methylpentanoyl-CoA + 4-methylpentanoate => (R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA


name: A + cholest-4,6-dien-3-one + H2O <=> 25-hydroxycholest-4,6-dien-3-one + AH2


name: ATP + L-aspartate + NK13650 D = AMP + diphosphate + H(+) + NK13650 C


name: glycylglycylglycine(out) + n H(+)(out) <=> glycylglycylglycine(in) + n H(+)(in)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Sus scrofa)


name: 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 4-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase]


name: XPO1 (CRM1) binds to BACH1:Hemes (Gallus gallus)


name: IL1R1:IL1:IL1RAP binds MYD88 homodimer (Gallus gallus)


name: formaldehyde + H2O + NAD(+) + sulfite => methanesulfonate + NADH + O2


name: ATP + H2O + N-11-cis-retinylidenephosphatidylethanolamine(out) => ADP + H(+) + N-11-cis-retinylidenephosphatidylethanolamine(in) + phosphate


name: 11-cis-retinol--[retinol-binding protein] + NAD(+) = 11-cis-retinal--[retinol-binding protein] + H(+) + NADH


name: H2O + N-(aminomethyl)urea => N-(hydroxymethyl)urea + NH4(+)


name: 2xPPCS ligates PPanK with Cys (Bos taurus)


name: p-Y420-FYN is phosphorylated on S21 (Caenorhabditis elegans)


name: CPNEs bind PL (Dictyostelium discoideum)


name: Initiation of RNA Polymerase III Productive Transcription (Homo sapiens)


name: H2O + N(2)-(1-hydroxy-2-oxopropyl)-dGTP = dGTP + H(+) + lactate


name: SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Canis familiaris)


name: tBID binds to inactive BAX protein (Danio rerio)


name: Phosphorylation of PLC-gamma by p-BTK/p-SYK (Bos taurus)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Caenorhabditis elegans)


name: H2O + pyrrole-2-carboxylate => 1H-pyrrole + hydrogencarbonate


name: PKA phosphorylates NOS3 (eNOS) on serine-633 (Schizosaccharomyces pombe)


name: crocetin + UDP-alpha-D-glucose = beta-D-glucosyl crocetin + UDP


name: 2 H(+) + malonate + NADH => 3-oxopropanoate + H2O + NAD(+)


name: Activation of highly calcium permeable nicotinic acetylcholine receptors (Bos taurus)


name: Elongation of stearidonoyl-CoA to eicosatetraenoyl-CoA (Plasmodium falciparum)


name: AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Gallus gallus)


name: 3,4-dihydroxybenzoyl-[aryl-carrier protein] + N(8),N'(8)-citryl-bis(spermidine) <=> H(+) + holo-[aryl-carrier protein] + N(1)-(3,4-dihydroxybenzoyl)-N(8),N'(8)-citryl-bis(spermidine)


name: 1-octadecanoyl-2-(15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+)


name: UCHL3, SENP8 cleave NEDD8 (Canis familiaris)


name: 1-hydroxy-2-naphthoate + O2 <=> (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H(+)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Danio rerio)


name: mating-type alpha-factor pheromone receptor activity


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Homo sapiens)


name: 2-oxoglutarate + L-lysyl-[protein] + O2 = 4-hydroxy-L-lysyl-[protein] + CO2 + succinate


name: (9Z)-hexadecenoyl-[ACP] + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) <=> (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + holo-[ACP]


name: 5-methyl-phenazine-1-carboxylate + S-adenosyl-L-homocysteine => phenazine-1-carboxylate + S-adenosyl-L-methionine


name: HNF1B binds the IRX2 gene (Homo sapiens)


name: Autocatalytic activation of MMP7 (Bos taurus)


name: Connexin synthesis (generic) (Homo sapiens)


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Rattus norvegicus)


name: genkwanin + H(+) + S-adenosyl-L-homocysteine => apigenin + S-adenosyl-L-methionine


name: Rnd1 interacts with Plexin-B1:Sema4D (Rattus norvegicus)


name: STAB1:ligand is endocytosed (Mus musculus)


name: TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)


name: [(3R)-hydroxybutanoate](n) + H2O => (3R)-hydroxybutanoate trimer + [(3R)-hydroxybutanoate](n-3) + H(+)


name: [PQQ precursor protein] + S-adenosyl-L-methionine => 5'-deoxyadenosine + E-Y cross-linked-[PQQ precursor protein] + H(+) + L-methionine


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Canis familiaris)


name: Proteasome degrades polyubiquitinated PTEN (Canis familiaris)


name: Phosphorylation of EGFR by SRC kinase (Gallus gallus)


name: Y693-STAT4 dimer translocates to the nucleus (Caenorhabditis elegans)


name: KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + sesquisabinene A


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dCMP + H2O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyl-dCMP


name: SARS-CoV-1 7a binds BCL2L1 (Homo sapiens)


name: TRAF3 binds TICAM1:activated TLR4 complex (Canis familiaris)


name: TGFBR3 binding to ARRB1/2 (Mus musculus)


name: L-glutamine(out) + L-threonine(in) + Na(+)(out) => L-glutamine(in) + L-threonine(out) + Na(+)(in)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + succinate


name: COMT binds COMT Inhibitors (Gallus gallus)


name: ATR activation at DNA DSBs (Gallus gallus)


name: Phosphorylation of SHC by SYK kinase (Bos taurus)


name: Separation of elongating transcript from template (Mus musculus)


name: L-glutamate + O-phospho-L-serine = H(+) + N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + phosphate


name: FANCD2:FANCI complex and UBE2T bind ICL-DNA associated with the FA core complex (Bos taurus)


name: Cytoslic carboxylases translocate to mitochondrial matrix (Danio rerio)


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Homo sapiens)


name: Pellino ubiquitinates IRAK1 (Danio rerio)


name: HTRA1 hydrolyzes ACAN (Aggrecan) (Rattus norvegicus)


name: CBL autoubiquitinates (Rattus norvegicus)


name: dimethylallyl diphosphate + H2O = diphosphate + prenol


name: Interaction of SOS-1 to Tie2 bound  Grb2 (Gallus gallus)


name: IFNAR1:TYK2 binds TYK2 inhibitors (Mus musculus)


name: acetylsalicylate + L-lysyl-[protein] = H(+) + N(6)-acetyl-L-lysyl-[protein] + salicylate


name: cyclohexa-1,5-diene-1-carbonyl-CoA + H2O = 6-hydroxycyclohex-1-ene-1-carbonyl-CoA


name: 3,4-dihydroxyphenylacetate + H(+) => 4-methylcatechol + CO2


name: H2O + L-rhamnono-1,4-lactone <=> H(+) + L-rhamnonate


name: POLI incorporates dNMP opposite to damaged DNA base (Rattus norvegicus)


name: a ganglioside GT1b (d18:1(4E)) + H2O => a ganglioside GD1b (d18:1(4E)) + N-acetylneuraminate


name: NVP-TAE684-resistant ALK mutants don't bind NVP-TAE684 (Homo sapiens)


name: Active calmodulin binds CAMK2 (Drosophila melanogaster)


name: RAC2:GTP binds NOX2 complex (Mus musculus)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(R)-HEPE to 18(R)-RvE1 (Saccharomyces cerevisiae)


name: Spontaneous hydrolysis of an internal thioester bond in complement factor C3 (Gallus gallus)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Dictyostelium discoideum)


name: 2-oxoglutarate + nonyl sufate + O2 <=> CO2 + H(+) + nonanal + succinate + sulfate


name: RBFOX1 gene expression is inhibited by MECP2 (Homo sapiens)


name: Activated JNKs phosphorylate c-JUN (Sus scrofa)


name: L-lysyl-L-alpha-amino acid(in) => L-lysyl-L-alpha-amino acid(out)


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Drosophila melanogaster)


name: SLC5A6 transports vitamins from extracellular region to cytosol (Sus scrofa)


name: hexadecan-1-ol + O2 <=> H2O2 + hexadecanal


name: carbovir + IMP => carbovir monophosphate + inosine (Bos taurus)


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine


name: Excess cysteine yields lanthionine and H2S (Caenorhabditis elegans)


name: SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: RHOD binds effectors at the mitochondrial outer membrane (Rattus norvegicus)


name: Activation of IKK complex (Rattus norvegicus)


name: sphinga-4E,14Z-dienine-1-phosphate = (2E,12Z)-hexadecadienal + phosphoethanolamine


name: (3R)-hydroxy-(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA = (2E,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + H2O


name: HLTF binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Saccharomyces cerevisiae)


name: a di-trans,poly-cis-dolichyl phosphate + H2O <=> a di-trans,poly-cis-dolichol + phosphate


name: (2,4-dichlorophenoxy)acetate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + CO2 + glyoxylate + succinate


name: TRIAP1:PRELID1, PRELID3A transports PA from the outer to the inner mitochondrial membrane (Saccharomyces cerevisiae)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Xenopus tropicalis)


name: 2 glutathione amide + NAD(+) => glutathione amide disulfide + H(+) + NADH


name: Inactivation of Rho-GTP by p190RhoGAP (Danio rerio)


name: NT5E:Zn2+ hydrolyses NAD+ (Rattus norvegicus)


name: H(+) + quercetin 3-O-beta-D-glucoside + UDP => quercetin + UDP-alpha-D-glucose


name: IL3RB is phosphorylated on Ser-585 (Rattus norvegicus)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Mus musculus)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Dictyostelium discoideum)


name: GPI dimer isomerizes Fru(6)P to G6P (Schizosaccharomyces pombe)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Rattus norvegicus)


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Bos taurus)


name: 4-chlorobenzoyl-CoA + AMP + diphosphate => 4-chlorobenzoate + ATP + CoA


name: Release of platelet cytosolic components (Mus musculus)


name: Cdt1 is displaced from the pre-replicative complex (Mus musculus)


name: STRAP binds phosphorylated TGF-beta receptor complex (Homo sapiens)


name: [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine => [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine


name: (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphate + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O


name: EHHADH hydrates trans-2,3-dehydrohexacosanoyl-CoA (Caenorhabditis elegans)


name: CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Canis familiaris)


name: Transcriptional activation of AGPAT1 by ChREBP:MLX (Homo sapiens)


name: benzyl alcohol + NAD(+) = benzaldehyde + H(+) + NADH


name: gamma-secretase cleaves EPHB2 (Mus musculus)


name: Oligomerization of CARMA1 (Canis familiaris)


name: CDC42 translocates to the endoplasmic reticulum membrane (Danio rerio)


name: Thiosulfate can transfer its sulfur atom to glutathione (Xenopus tropicalis)


name: DHFR dimer binds DHFR inhibitors (Homo sapiens)


name: cyclohex-1-ene-1-carbonyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = cyclohexa-1,5-diene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]


name: H(+)(out) + L-histidine(out) + L-ornithine(in) => H(+)(in) + L-histidine(in) + L-ornithine(out)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Canis familiaris)


name: Active G alpha (z) binds RGS proteins (Mus musculus)


name: STUB1 (CHIP) ubiquitinates SMAD3 (Canis familiaris)


name: G6PC hydrolyzes G6P to Glc and Pi (liver) (Xenopus tropicalis)


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Homo sapiens)


name: 4-chlorobenzoyl-CoA + H2O => 4-hydroxybenzoyl-CoA + chloride + H(+)


name: Translocation of Vav1 to CD28 (Xenopus tropicalis)


name: (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O <=> (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol


name: IGF1,2:IGF1R autophosphorylates (Xenopus tropicalis)


name: ALD3A1 oxidises 4HPCP to CXPA (Homo sapiens)


name: STING recruits TBK1 and STAT6 (Drosophila melanogaster)


name: 1,7-decanediol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => decan-1-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: CDK5 phosphorylates DARPP-32 on Thr75 (Sus scrofa)


name: TRAFs bind RANK:RANKL (Xenopus tropicalis)


name: (R)-2-methyl-3-oxopropanoate + H(+) + NADH => (R)-3-hydroxy-2-methylpropanoate + NAD(+)


name: (15Z)-tetracosenoyl-CoA + sphing-4-enine => CoA + H(+) + N-(15Z-tetracosenoyl)-sphing-4-enine


name: VTN binds Plasminogen activator inhibitor- 1 (Bos taurus)


name: Aggresome dissociates from dynein and microtubule (Xenopus tropicalis)


name: Rsu-1 interacts with Pinch1 (Homo sapiens)


name: TRPA1 tetramer transports Ca2+ from extracellular region to cytosol (Drosophila melanogaster)


name: a fatty acid + ethanolamine => an N-acylethanolamine + H2O


name: D-ribulose 1-phosphate <=> dihydroxyacetone phosphate + glycolaldehyde


name: ATP + chenodeoxycholate + CoA <=> AMP + chenodeoxycholoyl-CoA + diphosphate


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Gallus gallus)


name: The Kiss receptor GPR54 binds kisspeptin (Canis familiaris)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H(+)


name: 6-demethylmitomycin B + S-adenosyl-L-methionine => mitomycin B + S-adenosyl-L-homocysteine


name: 3-oxoisopentadecanoyl-CoA + CO2 + CoA => 11-methyldodecanoyl-CoA + H(+) + malonyl-CoA


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Caenorhabditis elegans)


name: IRAK1 phosphorylates Pellino (Mus musculus)


name: 3-O-beta-D-glucosyl-D-glucuronate + phosphate <=> aldehydo-D-glucuronate + alpha-D-glucose 1-phosphate


name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond


name: "Catalyzing the reaction X-H + Y-H = 'X-Y'"


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Rattus norvegicus)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Bos taurus)


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose <=> [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n+1)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: Ubiquitinated RNF41 binds P-USP8 (Drosophila melanogaster)


name: IL37:2x(CASP1(120-197):CASP1(317-404)) cleaves IL37 (Canis familiaris)


name: ATP + H2O + tetracosanoate(in) = ADP + H(+) + phosphate + tetracosanoate(out)


name: EFCAB7:IQCE binds EVC2:EVC (Canis familiaris)


name: Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Drosophila melanogaster)


name: AMOT proteins bind YAP1 (Xenopus tropicalis)


name: RNAP transcribes Mtb RNA polyanion (Homo sapiens)


name: n H(+)(out) + serotonin(in) <=> n H(+)(in) + serotonin(out)


name: (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H2O => (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA


name: p14ARF mutants do not bind C1QBP (Homo sapiens)


name: TMP, uridine 2', 3', or 5' monophosphates, or deoxyuridine 3' or 5' monophosphates + H2O => thymidine or (deoxy)uridine + orthophosphate [NT5C] (Bos taurus)


name: pro-defensin alpha 5 is stored in Paneth cell granules (Rattus norvegicus)


name: large conductance calcium-activated potassium channel activity


name: Glucagon-like Peptide 1 is secreted from intestinal L cells (Canis familiaris)


name: dioctanoylglycerol + H2O = H(+) + octanoate + octanoylglycerol


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Saccharomyces cerevisiae)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + O2 => CO2 + formaldehyde + N(6)-methyl-L-lysyl(27)-[histone H3] + succinate


name: glutarate(out) + taurocholate(in) => glutarate(in) + taurocholate(out)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione <=> (12S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: Raf dimer inhibitors bind RAF heterodimers (Gallus gallus)


name: HEXB cleaves the terminal GalNAc from small HA fragments (Homo sapiens)


name: D-maltobionate + H(+) => D-maltobiono-1,5-lactone + H2O


name: chylomicron remnant + apoE => chylomicron remnant:apoE complex (Bos taurus)


name: HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Danio rerio)


name: Phosphorylated FUNDC1 links damaged mitochondria to LC3 (Xenopus tropicalis)


name: CYP26A1,B1,C1 4-hydroxylate atRA (Mus musculus)


name: p-S295-PDE3B hydrolyses cAMP to AMP (Dictyostelium discoideum)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + O2 <=> CO2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3] + succinate


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Drosophila melanogaster)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Drosophila melanogaster)


name: OSCN- reacts with Cys residues (Homo sapiens)


name: G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) (Bos taurus)


name: 1-O-alkyl-2,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine => 1-O-alkyl-2-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (24S)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Caenorhabditis elegans)


name: A + D-serine + H2O = 3-hydroxypyruvate + AH2 + NH4(+)


name: Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)


name: LC3 is cleaved by ATG4 (Drosophila melanogaster)


name: Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Dictyostelium discoideum)


name: 2-chloro-6-nitrotoluene + NADH + O2 = 4-chloro-3-methylcatechol + NAD(+) + nitrite


name: ATP + CoA + IC-asc-C9 <=> AMP + diphosphate + IC-asc-C9-CoA


name: ADP-L-glycero-beta-D-manno-heptose + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) <=> ADP + H(+) + L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli)


name: p-VAV family:PIP3 binds RAC1:GDP (Drosophila melanogaster)


name: CTP(out) + dGTP(in) => CTP(in) + dGTP(out)


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-ethanolamine => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + H(+) + malonyl-CoA = (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + CO2 + CoA


name: H2O + isopenicillin N + phenylacetyl-CoA => CoA + H(+) + L-2-aminoadipate + penicillin G


name: BH2 binding can lead to eNOS uncoupling (Homo sapiens)


name: diphosphate + germacrene A => (2E,6E)-farnesyl diphosphate


name: acetyl-CoA + 6 H(+) + holo-[ACP] + 6 malonyl-CoA = 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP] + 6 CO2 + 7 CoA


name: diphosphate + discoidol => (2E,6E)-farnesyl diphosphate + H2O


name: peregrinol diphosphate <=> (13R)-9,13-epoxylabd-14-ene + diphosphate


name: Caspase mediated cleavage of beta-catenin (Homo sapiens)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Schizosaccharomyces pombe)


name: 2-oxoglutarate + 3-hydroxy-L-phenylalanine = 3-(3-hydroxyphenyl)pyruvate + L-glutamate


name: Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha  (Danio rerio)


name: Phosphorylation of p-KIT on Y900 by Src kinases (Gallus gallus)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Drosophila melanogaster)


name: acetyl-CoA + succinate => acetate + succinyl-CoA


name: acetyl-CoA + 10 H(+) + holo-[polyketide synthase] + 5 malonyl-CoA + 5 NADPH => 5 CO2 + 6 CoA + dodecapentaneoyl-[polyketide synthase] + 5 H2O + 5 NADP(+)


name: Ligand-independent dimerization of FLT3 mutants (Homo sapiens)


name: Cleavage of thymine by TDG glycosylase (Bos taurus)


name: ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Rattus norvegicus)


name: GPR161 is internalized (Xenopus tropicalis)


name: CMP-N-acetyl-beta-neuraminate + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine = CMP + H(+) + N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-galactosamine


name: 2 Na(+)(in) + tetrahydroxoborate(in) = 2 Na(+)(out) + tetrahydroxoborate(out)


name: 2-aminopentanenitrile + H(+) + 2 H2O <=> L-2-aminopentanoate + NH4(+)


name: indolepyruvate ferredoxin oxidoreductase activity


name: Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Mus musculus)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Sus scrofa)


name: SLC25A12,13 exchange L-Glu and L-Asp (Caenorhabditis elegans)


name: 17alpha-hydroxyprogesterone + NADPH + O2 <=> acetate + androst-4-ene-3,17-dione + H2O + NADP(+)


name: DAG is metabolized by DAGL to 2-AG (Rattus norvegicus)


name: SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Mus musculus)


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Dictyostelium discoideum)


name: Elongation of pre-rRNA transcript (Bos taurus)


name: NGF homodimer binds to p75NTR (Mus musculus)


name: LHPP:Mg2+ dimer hydrolyses PPi (Bos taurus)


name: Vesicular inhibitory amino acid transport (Drosophila melanogaster)


name: DENND5A,B exchange GTP for GDP on RAB39 (Bos taurus)


name: aminoacetaldehyde + 3 H(+) + 2 reduced [4Fe-4S]-[ferredoxin] + sulfite => H2O + 2 oxidized [4Fe-4S]-[ferredoxin] + taurine


name: Translocation of RIAM to plasma membrane (Rattus norvegicus)


name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Homo sapiens)


name: 6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) = (+)-costunolide + H2O


name: EXT1:EXT2 transfers GlcNAc to heparan (Sus scrofa)


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Homo sapiens)


name: H2O + 2 oxidized [4Fe-4S]-[ferredoxin] + taurine => aminoacetaldehyde + 3 H(+) + 2 reduced [4Fe-4S]-[ferredoxin] + sulfite


name: benzyl cetraxate + H2O <=> benzyl alcohol + cetraxate + H(+)


name: protein binding involved in heterotypic cell-cell adhesion


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Bos taurus)


name: Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Bos taurus)


name: Formation of Cyclin E:Cdk2 complexes (Xenopus tropicalis)


name: (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH


name: PalmS-ESRs:CAVs translocate to plasma membrane (Rattus norvegicus)


name: decanoate ester + H2O <=> an aliphatic alcohol + decanoate + H(+)


name: ADP-D-ribose + H2O <=> AMP + D-ribose 5-phosphate + 2 H(+)


name: 1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: ALOX15 oxidises 17(S)-Hp-DHA to PDX (Rattus norvegicus)


name: beta-alanyl-dopamine + H2O = beta-alanine + dopamine


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Canis familiaris)


name: ALDH3A2-1 oxidises HD2NAL to PALM (Saccharomyces cerevisiae)


name: H2O + L-phenylalanine + O2 <=> 3-phenylpyruvate + H2O2 + NH4(+)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Homo sapiens)


name: DAAM1 recruits GTP-bound RHOA (Bos taurus)


name: NaS1 co-transports sulphate and a sodium ion (Xenopus tropicalis)


name: chylomicron => TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols (Bos taurus)


name: PRLR:JAK2 dimerizes (Xenopus tropicalis)


name: ATP + H2O + selenite(out) <=> ADP + H(+) + phosphate + selenite(in)


name: IQGAP1 binds CLIP1 and microtubules (Bos taurus)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Bos taurus)


name: 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al (Mus musculus)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + a 1-acyl-sn-glycero-3-phosphocholine + H(+)


name: 3-hydroxyglutarate(in) + 3 Na(+)(in) => 3-hydroxyglutarate(out) + 3 Na(+)(out)


name: (9Z)-octadecenoate + 9-hydroxy-octadecanoate + H(+) => 9-(9Z-octadecenoyloxy)-octadecanoate + H2O


name: Association of DFF40 with DFF45 (Xenopus tropicalis)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Danio rerio)


name: PARP1 or PARP2 PARylates DDB2 and autoPARylates (Xenopus tropicalis)


name: RANBP2 SUMOylates RANBP2 with SUMO1 (Homo sapiens)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Canis familiaris)


name: (1R,2R,4S)-isodihydrocarveol + NAD(+) <=> (1R,4S)-isodihydrocarvone + H(+) + NADH


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Mus musculus)


name: CSNK2-mediated phosphorylation of DVL (Caenorhabditis elegans)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine => 1-O-acyl-N-(acetyl)-sphing-4-enine + 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: phenylglyoxylate dehydrogenase (acylating) activity


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Saccharomyces cerevisiae)


name: PCSK9:LDLR:Clathrin-coated vesicle transport from plasma membrane to endolysosome (Bos taurus)


name: Binding of TFIIIC to Type 2 promoter (Rattus norvegicus)


name: 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester => Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + S-adenosyl-L-methionine


name: AGT(34-41) binds to AGTR1 (Caenorhabditis elegans)


name: PNLIP:CLPS hydrolyses RPALM to atROL and PALM (Gallus gallus)


name: FKBP1A binds tacrolimus (Drosophila melanogaster)


name: cholate + L-histidine = H2O + L-histidocholate


name: a medium-chain 3-oxoacyl-[ACP] + dihydroxyacetone phosphate <=> a 2-oxo-3-(phosphooxy)propyl medium-chain 3-oxoalkanoate + holo-[ACP]


name: ethylenediaminetriacetate + FMNH2 + O2 <=> ethylenediaminediacetate + FMN + glyoxylate + H(+) + H2O


name: tricarboxylic acid transmembrane transporter activity


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Sus scrofa)


name: Clathrin internalises EPH:EFN complexes (Gallus gallus)


name: Formation of the Spliceosomal Bact complex (Mus musculus)


name: ATP(in) + CoA(in) + decanoate(out) + H(+)(out) = AMP(in) + decanoyl-CoA(in) + diphosphate(in) + H(+)(in)


name: albendazole S-oxide + H2O + NADP(+) => albendazole + H(+) + NADPH + O2


name: TSTA3 dimer epimerises GDP-DHDMan to GDP-KDGal (Bos taurus)


name: AKR1B1 reduces Glc to D-sorbitol (Schizosaccharomyces pombe)


name: Activated TP receptor binds G-proten Gq (Sus scrofa)


name: HLCS biotinylates ACACA:Mn2+ (Drosophila melanogaster)


name: alpha-maltohexaose + phosphate = alpha-D-glucose 1-phosphate + alpha-maltopentaose


name: 3-(2-aminophenyl)-3-oxopropanal + H2O2 + NH4(+) => H2O + kynuramine + O2


name: (9Z)-hexadecenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate => 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: OCT3 mediates renal clearance of organic cations (Rattus norvegicus)


name: Formation of the Spliceosomal C* complex (Canis familiaris)


name: RHOGAPP190 activates GTP hydrolysis by RHO1:GTP (Drosophila melanogaster)


name: precorrin-6B + 2 S-adenosyl-L-methionine => CO2 + 3 H(+) + precorrin-8X + 2 S-adenosyl-L-homocysteine


name: STAB1 (FEEL-1) binds ligands (Bos taurus)


name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate (Xenopus tropicalis)


name: AKR dimers reduce AFBDHO to AFBDOH (Homo sapiens)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Mus musculus)


name: TRIM33 monoubiquitinates SMAD4 (Sus scrofa)


name: abieta-8(14),12-diene + diphosphate => (+)-copalyl diphosphate


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Rattus norvegicus)


name: LONP1 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA (Bos taurus)


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Danio rerio)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Sus scrofa)


name: SPP1 gene expression is stimulated by RUNX3 (Homo sapiens)


name: L-alanine + pyridoxal 5'-phosphate <=> pyridoxamine 5'-phosphate + pyruvate


name: Activated cytosolic FGFR1 fusions bind PIK3CA (Homo sapiens)


name: 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA


name: demethylphylloquinone + H(+) + NADPH = demethylphylloquinol + NADP(+)


name: Deubiquitinated PTEN translocates to the cytosol (Homo sapiens)


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Canis familiaris)


name: RAB31 GEFs exchange GTP for GDP on RAB31 (Gallus gallus)


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Danio rerio)


name: NOX4, NOX5 reduce O2 to O2.- (Gallus gallus)


name: O2 + polyporic acid + reduced [NADPH--hemoprotein reductase] <=> ascocorynin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a sphingomyelin(in) <=> a sphingomyelin(out)


name: a fatty acid + beta-D-glucosyl-(1<->1)-sphing-4-enine => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O


name: dimethyl sulfide + H(+) + NADH + O2 = dimethyl sulfoxide + H2O + NAD(+)


name: Autocatalytic activation of MMP3 (Canis familiaris)


name: an N-acetyl-beta-D-glucosaminyl derivative + UDP-alpha-D-galactose <=> a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + H(+) + UDP


name: Binding of IRS to insulin receptor (Bos taurus)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione => (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Dictyostelium discoideum)


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Gallus gallus)


name: DKC1 binds SHQ1 (Saccharomyces cerevisiae)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Saccharomyces cerevisiae)


name: SEPHS2 phosphorylates H2Se to form SELP (Danio rerio)


name: a 14alpha-methyl steroid + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] => a Delta(14) steroid + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Xenopus tropicalis)


name: SLC38A4 (ATA3)-mediated uptake of arginine and lysine (Saccharomyces cerevisiae)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O = (N(2),N(2),N(7))-trimethyl-GMP + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+)


name: Damaged dsDNA becomes damaged DNA template (Homo sapiens)


name: NAD-dependent protein biotinidase activity


name: H2O + N(6)-biotinyl-L-lysyl-[protein] + NAD(+) = 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Membrane-bound CDH11 is cleaved to produce secreted CDH11 isoform (Xenopus tropicalis)


name: The complex of RUNX2 and WWTR1 (TAZ) binds the BGLAP gene promoter (Homo sapiens)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Rattus norvegicus)


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Danio rerio)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H2O => 2-(9Z-octadecenoyl)-glycerol + H(+) + octadecanoate


name: H(+)(in) + L-leucine(out) => H(+)(out) + L-leucine(in)


name: PRKAA2 phosphorylates nuclear NFE2L2 (Gallus gallus)


name: BRCA1-A complex deubiquitinates K63polyUb-histone H2A (Bos taurus)


name: acetyl-CoA + N-terminal L-(Asp/Glu)3-[protein] => CoA + H(+) + N-terminal N-acetyl-L-(Asp/Glu)3-[protein]


name: 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose <=> 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+)


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Saccharomyces cerevisiae)


name: p-S256-Aquaporin-2 passively transports water into cell (Bos taurus)


name: spermine dialdehyde => acrolein + N-(4-aminobutyl)-3-aminopropanal


name: PDSS1,2 ligates FPP to IPPP (Sus scrofa)


name: (9Z)-octadecenoyl-CoA + di-(9Z)-octadecenoylglycerol <=> 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + L-serine


name: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O <=> 3,5-dibromo-4-hydroxybenzoate + NH4(+)


name: [(1->3)-beta-D-glucosyl](n+1) + H(+) + UDP => [(1->3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose


name: acetate + H(+) + L-lupinate => O-acetyl-L-serine + zeatin


name: 2-acetamidofluorene + H2O + NAD(+) = H(+) + N-hydroxy-2-acetamidofluorene + NADH


name: IP subcomplex binds NDUFAF3, NDUFAF4, TIMMDC1 to form Intermediate 1 (Xenopus tropicalis)


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Bos taurus)


name: 2-carboxy-5-(dihydroxymethyl)furan + O2 <=> 2,5-dicarboxyfuran + H(+) + H2O2


name: (2R,3R)-dihydrokaempferol + O2 + reduced [NADPH--hemoprotein reductase] = (2R,3R)-dihydroquercetin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2'-deamino-2'-hydroxyneamine + UDP-alpha-D-glucose <=> H(+) + kanamycin D + UDP


name: (13Z)-3-oxodocosenoyl-CoA + H(+) + NADPH => (3R)-hydroxy-(13Z)-docosenoyl-CoA + NADP(+)


name: (S)-leucinol + H2O + NAD(+) => 1-hydroxy-4-methylpentan-2-one + H(+) + NADH + NH4(+)


name: SARS-CoV-1 S binds SFTPD 12mer (Homo sapiens)


name: chloride + FADH2 + melleolide F + O2 => 6'-chloromelleolide F + FAD + H(+) + 2 H2O


name: methionine adenosyltransferase regulator activity


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Homo sapiens)


name: 2 A + all-trans-zeta-carotene = 2 AH2 + all-trans-lycopene


name: a 14alpha-methyl steroid + 5 H(+) + 3 O2 + 6 reduced [2Fe-2S]-[ferredoxin] <=> a Delta(14) steroid + formate + 4 H2O + 6 oxidized [2Fe-2S]-[ferredoxin]


name: creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Rattus norvegicus)


name: (R)-dihydrolipoate + ATP + L-lysyl-[lipoyl-carrier protein] <=> AMP + diphosphate + H(+) + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein]


name: (5Z,8Z)-eicosadienoate + O2 = (5S)-hydroperoxy-(6E,8Z)-eicosadienoate


name: MFSD2A transports LPC from extracellular region to plasma membrane (Xenopus tropicalis)


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Drosophila melanogaster)


name: mature RAS proteins translocate to plasma membrane (Bos taurus)


name: ent-7alpha-hydroxykaur-16-en-19-oate + O2 + reduced [NADPH--hemoprotein reductase] <=> gibberellin A12 aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + H2O + NAD(+) = (E)-2-((N-methylformamido) methylene)succinate + 3 H(+) + NADH


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = 15,20-dihydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Sus scrofa)


name: "N-terminal amino-acid N(alpha)-acetyltransferase NatA"


name: G alpha (q) inhibits PI3K alpha (Mus musculus)


name: GADD45A gene expression is stimulated by FOXO3,FOXO4,(FOXO1) (Homo sapiens)


name: Superoxide reduces cytochrome c (Danio rerio)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Rattus norvegicus)


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Sus scrofa)


name: H2O + L-threonyl-L-threonine => 2 L-threonine


name: NEIL1 cleaves thymine glycol from damaged DNA (Sus scrofa)


name: G protein binds CX3CR1 on host cell surface (Homo sapiens)


name: chlorogenate + D-glucarate <=> 2-O-caffeoylglucarate + L-quinate


name: a 1,3-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine => a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycerol


name: 3alpha(S)-strictosidine + H2O <=> secologanin + tryptamine


name: 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH => NADP(+) + prephenate


name: DHCR24 reduces LAN to 24,25-dhLAN (Danio rerio)


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Canis familiaris)


name: H2O + N-hexanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-hexanoyl ethanolamine


name: ACSM2B-like proteins transform ST to ST-CoA (Canis familiaris)


name: Tropoelastin forms aggregate globules (Homo sapiens)


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Mus musculus)


name: TBX6 and LEF1:CTNNB1 bind the MSGN1 gene (Homo sapiens)


name: H(+) + N-hydroxy-2-acetamidofluorene + NADPH => 2-acetamidofluorene + H2O + NADP(+)


name: 8 H(+) + malonamoyl-[OxyC ACP] + 8 malonyl-CoA = 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Gallus gallus)


name: STING recruits TBK1 and STAT6 (Danio rerio)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Bos taurus)


name: TBC1D20 binds RAB1:GTP (Drosophila melanogaster)


name: (+)-sesamin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (+)-piperitol + O2 + reduced [NADPH--hemoprotein reductase]


name: FLNA binds PAK1 (Drosophila melanogaster)


name: S-ethyl-L-cysteine = 2-aminoprop-2-enoate + ethanethiol


name: Formation of lysyl-pyridinoline cross-links (Rattus norvegicus)


name: Association of Ku heterodimer with ends of DNA double-strand break (Mus musculus)


name: diphthine methyl ester synthase activity


name: ELOVL5 gene expression is stimulated by PPARG2:RXRA:MLL4(MLL3)-ASCOM complex (Homo sapiens)


name: 2-oxoglutarate + O2 + scopoletin = CO2 + fraxetin + succinate


name: Necl-1:Necl-2 trans heterodimer interaction (Canis familiaris)


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)


name: 1,2,3-tributanoylglycerol + H2O <=> butanoate + dibutanoylglycerol + H(+)


name: 3,5-dihydroxyanisole + H(+) + S-adenosyl-L-homocysteine => 1,3,5-trihydroxybenzene + S-adenosyl-L-methionine


name: Tethering of late endosome-derived vesicles by GARP, STX10:ST16:VTI1A and Golgins (Canis familiaris)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)6 (PP-Dol)1 (Xenopus tropicalis)


name: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA => (E)-feruloyl-CoA + H2O


name: PIAS1 SUMOylates SP3 with SUMO2 (Homo sapiens)


name: Transport (influx) of bile salts and acids by OATP-A (Danio rerio)


name: 3-O-alpha-D-glucosyl-L-rhamnose + phosphate <=> beta-D-glucose 1-phosphate + L-rhamnopyranose


name: 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+) => a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: 3 H(+) + N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine => N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine


name: GUCY2C trimer binds GUCA2A,B (Gallus gallus)


name: (2R)-O-phospho-3-sulfolactate + H2O => (2R)-3-sulfolactate + phosphate


name: Protesomal degradation of K48polyUb-TRAF3 (Gallus gallus)


name: D-galactose + D-glucose => H2O + melibiose


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Dictyostelium discoideum)


name: Formation of NELF complex  (Rattus norvegicus)


name: a fatty acid + H(+) + holo-[ACP] => a fatty acyl-[ACP] + H2O


name: PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Rattus norvegicus)


name: 2-oxobutanoate + glycine => (2S)-2-aminobutanoate + glyoxylate


name: K63polyUb-TAK1 autophosphorylates (Gallus gallus)


name: CHRM4 binds CHRM4 antagonists (Mus musculus)


name: RAC1:GTP binds NOX1 complex (Mus musculus)


name: TNF-α is cleaved by ADAM17 (TACE) (Homo sapiens)


name: Activated TP receptor binds G-protein  G13 (Sus scrofa)


name: a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose <=> an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc derivative + GDP + H(+)


name: 3-hydroxy-6-carboxyhexanoyl-CoA + H(+) => 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O


name: Active ARF recruits coatomer (Drosophila melanogaster)


name: NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs (Homo sapiens)


name: CYP21A2 21-hydroxylates PROG (Mus musculus)


name: A47934 + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + desulfo-A47934


name: CO2 + succinate + trans-4-hydroxy-L-proline => 2-oxoglutarate + L-proline + O2


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Bos taurus)


name: ATP(in) + UTP(out) => ATP(out) + UTP(in)


name: [protein]-dithiol + a hydroperoxide <=> [protein]-disulfide + an alcohol + H2O


name: an acyl phosphate + H2O <=> a carboxylate + H(+) + phosphate


name: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-ribonucleoside in mRNA + H(+) + NAD(+)


name: diphosphate + Fe(II)-heme o => (2E,6E)-farnesyl diphosphate + H2O + heme b


name: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) => biphenyl-2,3-diol + O2


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Homo sapiens)


name: Uptake of Noradrenaline (Rattus norvegicus)


name: Release of mature NEDD8 (Dictyostelium discoideum)


name: (2Z,6Z)-farnesyl diphosphate = diphosphate + germacrene C


name: TP53 stimulates PLK3 expression (Homo sapiens)


name: cyclohexane-1,3-dione + H2O <=> 5-oxohexanoate + H(+)


name: CHEK2 phosphorylates TP53 (Rattus norvegicus)


name: 2-oxopentanoate + N(omega),N(omega)-dimethyl-L-arginine <=> 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminopentanoate


name: Interaction of Tie2 and Grb14 (Bos taurus)


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Mus musculus)


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Danio rerio)


name: (R)-3-phosphomevalonate + ATP = (R)-3,5-bisphosphomevalonate + ADP + H(+)


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + a 2-acyl-sn-glycero-3-phosphocholine + H(+)


name: 2-(dihydroxymethyl)-5-formylfuran + O2 = 2-carboxy-5-formylfuran + H(+) + H2O2


name: (Z)-beta-farnesene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: Excision of 8-oxoguanine by OGG1 glycosylase (Rattus norvegicus)


name: SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Rattus norvegicus)


name: (R)-synephrine + H(+) + S-adenosyl-L-homocysteine => (R)-octopamine + S-adenosyl-L-methionine


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Dictyostelium discoideum)


name: (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+) + NADH => (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O + NAD(+)


name: Activated FGFR2 phosphorylates FRS2 (Canis familiaris)


name: 2-ethyl-L-serine => (2S)-2-aminobutanoate + formaldehyde


name: Recruitment of BCAR1 to PTK2 complex (Mus musculus)


name: (3S)-hydroxy-(9Z-octadecenoyl)-CoA + NAD(+) <=> 3-oxo-(9Z-octadecenoyl)-CoA + H(+) + NADH


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Homo sapiens)


name: chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] => 3,8-divinyl chlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Homo sapiens)


name: cysteamine S-phosphate + H2O = cysteamine + phosphate


name: E2F1/2/3 stimulates EED transcription (Homo sapiens)


name: STING ubiquitination by TRIM32 or TRIM56 (Rattus norvegicus)


name: glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)


name: SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Canis familiaris)


name: MECP2:CREB1 complex binds SLC2A3 gene (Homo sapiens)


name: FA2H hydroxylates 1,2-saturated fatty acids (Xenopus tropicalis)


name: Aberrant alternative splicing yields a secreted FGFR2 IIIa TM disease variant (Homo sapiens)


name: USP5 cleaves polyubiquitin (Drosophila melanogaster)


name: H2O + kaempferol 3-O-beta-D-glucoside <=> beta-D-glucose + kaempferol


name: IL7 binds HGF(495-728) to form PPBSF (Homo sapiens)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Dictyostelium discoideum)


name: [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity


name: 8-hydroxycasbene + O2 + reduced [NADPH--hemoprotein reductase] = 4,8-dihydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Fatty acid ligands activate PPARA (Homo sapiens)


name: a sphingomyelin + H2O => a carboxylate + sphing-4-enine-phosphocholine


name: phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate (Xenopus tropicalis)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5A/B at the plasma membrane (Drosophila melanogaster)


name: RNA Polymerase II Promoter Opening: First Transition (Mus musculus)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: 2 Fe(III)-[cytochrome c] + H2O + octanal <=> 2 Fe(II)-[cytochrome c] + 3 H(+) + octanoate


name: Sulfate is exported to the cytosol in exchange for dicarboxylate (Sus scrofa)


name: (R)-2,3-diaminopropanoate + H(+) + H2O => 2 NH4(+) + pyruvate


name: Phosphorylation of Cyclin D1 at T286 by glycogen synthase kinase-3 beta (Homo sapiens)


name: a ganglioside Ac-O-7-GT3 <=> a ganglioside Ac-O-8-GT3


name: Phosphorylation of FANCG at S7 (Gallus gallus)


name: BIL binds GSTA1, FABP1 (Xenopus tropicalis)


name: STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Canis familiaris)


name: 5,6-dihydrouridine(47) in tRNA + NAD(+) = H(+) + NADH + uridine(47) in tRNA


name: D-sorbitol + NAD(+) => H(+) + keto-D-fructose + NADH


name: (E)-sinapate + choline + H(+) => H2O + O-sinapoylcholine


name: CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Sus scrofa)


name: Galanin receptors can bind galanin (Bos taurus)


name: fructose 1,6-bisphosphate 1-phosphatase activity


name: E2F1 binds the POLA1 gene promoter (Homo sapiens)


name: (S)-2-amino-6-oxohexanoate + holo-[LYS2 peptidyl-carrier protein] + NADP(+) <=> H(+) + L-2-aminoadipyl-[LYS2 peptidyl-carrier protein] + NADPH


name: (3R)-hydroxy-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA = (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Rattus norvegicus)


name: a 2-acyl-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: SRC phosphorylates RUNX3 (Gallus gallus)


name: GBE1 catalyzes branch formation in polyGlc-GYG2 complexed with GYS2-a (Homo sapiens)


name: L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine => H(+) + N(6)-methyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine


name: HIV Promoter Opening: First Transition (Homo sapiens)


name: D-glucaro-1,5-lactone + H(+) + NADH => beta-D-glucuronate + NAD(+)


name: H2O + N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine <=> L-asparagine + N-acetyl-D-glucosamine


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Drosophila melanogaster)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Saccharomyces cerevisiae)


name: CYP51A1 demethylates LNSOL (Schizosaccharomyces pombe)


name: 4-hydroxybenzoyl-CoA + chloride + H(+) => 4-chlorobenzoyl-CoA + H2O


name: ADP + H(+) + O-phospho-L-tyrosyl-[protein] => ATP + L-tyrosyl-[protein]


name: ABCA12 transports lipids from cytosol to extracellular region (Caenorhabditis elegans)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Rattus norvegicus)


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Sus scrofa)


name: 2 H(+) + NADPH + 2 O2 + protoviolaceinate => CO2 + 2 H2O + NADP(+) + violacein


name: 2-oxoglutarate + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate = L-2-acetamido-6-oxoheptanedioate + L-glutamate


name: alpha-maltoheptaose + beta-D-glucose => alpha-maltohexaose + beta-maltose


name: 7-dehydrodesmosterol + S-adenosyl-L-methionine = 5-dehydroepisterol + H(+) + S-adenosyl-L-homocysteine


name: RUNX2:CBFB binds the LGALS3 gene promoter (Homo sapiens)


name: 27-hydroxysterol binds ESR1, ESR2 (Mus musculus)


name: (2Z,6E)-farnesyl diphosphate => diphosphate + gamma-cadinene


name: Formation of the SCF-FBXL7 complex (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O => a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Xenopus tropicalis)


name: (S)-methioninol + H2O + NAD(+) => 1-hydroxy-4-(methythio)butan-2-one + H(+) + NADH + NH4(+)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Caenorhabditis elegans)


name: NAD(P)H dehydrogenase (quinone) activity


name: Cleavage of ethenoadenine by MPG glycosylase (Mus musculus)


name: a ganglioside Ac-O-7-GD2 + CoA => a ganglioside GD2 + acetyl-CoA


name: H2O + NADP(+) + nitrous oxide = H(+) + NADPH + 2 nitric oxide


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: a 1-acylglycerone 3-phosphate + H(+) + NADPH => a 1-acyl-sn-glycero-3-phosphate + NADP(+)


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + an acyl-CoA => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: Formation of fatty acid synthase (FAS) dimer (Xenopus tropicalis)


name: GAB1 phosphorylation by EGFR kinase (Danio rerio)


name: PRKN ubiquitinates MOM substrates (Danio rerio)


name: (1-deoxy-D-fructos-1-yl)amine + an aldehyde + H2O2 => an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + H2O + O2


name: 2'-deoxyguanosine + ATP <=> ADP + dGMP + H(+)


name: 2-deoxy-6-phospho-D-glucono-1,5-lactone + H(+) + NADPH => 2-deoxy-D-glucose 6-phosphate + NADP(+)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Caenorhabditis elegans)


name: Formation of ADAR2  homodimer (Caenorhabditis elegans)


name: (9Z)-octadecenoyl-CoA + 1-dodecanoylglycerol <=> 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: 3'-phosphoadenylyl sulfate + 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(beta-D-glucuronate) => 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Sus scrofa)


name: 7beta-hydroxy-3,12-dioxo-5beta-cholan-24-oate + NADP(+) => dehydrocholate + H(+) + NADPH


name: (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate => (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate


name: Activated PKC-alpha  activate MMP3 (Gallus gallus)


name: AH2 + O2 + pregna-4,9(11)-diene-3,20-dione => 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H2O


name: RHOC translocates to the endoplasmic reticulum membrane (Canis familiaris)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Danio rerio)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-hexacosanoyl-(4R)-hydroxysphinganine + O2 = 2 Fe(III)-[cytochrome b5] + H2O + N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine


name: 17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-9-hydroperoxy-20-hydroxy-(5Z,7E,11Z,14Z)-eicosatetraenoate


name: H(+) + UDP-alpha-D-galacturonate <=> CO2 + UDP-beta-L-arabinopyranose


name: 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O => (9Z)-octadecenoate + 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H(+)


name: FASTKD2 binds 16S rRNA and MT-ND6 mRNA (Homo sapiens)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate + 2H+ (Rattus norvegicus)


name: TPI1 isomerizes GA3P to DHAP (Sus scrofa)


name: A + a primary alcohol = AH2 + an aldehyde


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + diphosphate


name: LRR FLII-interacting protein 1 associates with beta-catenin (Homo sapiens)


name: The FA anion diffuses away laterally from UCP (Sus scrofa)


name: H2O + rhodomycin D <=> 10-carboxy-13-deoxycarminomycin + H(+) + methanol


name: an acyl-CoA + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + CoA


name: RAS proteins are depalmitoylated (Gallus gallus)


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA <=> (8Z,11Z,14Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: Na(+)(in) + uridine(in) => Na(+)(out) + uridine(out)


name: 4-oxocyclohexane-1-carboxylate + H(+) + NADH => NAD(+) + trans-4-hydroxycyclohexane-1-carboxylate


name: (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate => di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate


name: P2RY12 binds P2RY12 antagonists (Sus scrofa)


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Dictyostelium discoideum)


name: urokinase plasminogen activator (one-chain):uPAR -> urokinase plasminogen activator (two-chain):uPAR (Sus scrofa)


name: PIP2-bound p-S473-AKT1 mutant binds PIP2-bound PDPK1 (Homo sapiens)


name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Sus scrofa)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Gallus gallus)


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) + ATP + H2O = a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in) + ADP + H(+) + phosphate


name: (10bS,4aR)-noroxomaritidine + H(+) + NADPH => (10bS,4aR)-oxomaritidine + NADP(+)


name: N-hexanoyl-sphing-4-enine-1-phosphocholine = choline + N-(hexanoyl)-sphing-4-enine-1,3-cyclic phosphate


name: formate + H(+) + hydroxymethylphosphonate => 2-hydroxyethylphosphonate + O2


name: IL34 dimer binds CSF1R (Xenopus tropicalis)


name: 3'-dephospho-CoA + ATP => 2'-(5''-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine


name: (2,5-ethylene furandicarboxylate)(n) + 2 H2O = (2,5-ethylene furandicarboxylate)(n-1) + 2,5-dicarboxyfuran + ethylene glycol + 2 H(+)


name: AMP + diphosphate + hexanoyl-CoA => ATP + CoA + hexanoate


name: (R)-4'-phospho-S-sulfopantetheine + H2O = (R)-S-sulfopantetheine + phosphate


name: hexadecanoyl-CoA + sn-glycerol 3-phosphate <=> 1-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: (2S,3S)-2-methylcitrate <=> 2-methyl-trans-aconitate + H2O


name: P4HB forms mixed disulphides with Hh precursors (Rattus norvegicus)


name: ATP + H2O + uroporphyrin I(in) <=> ADP + H(+) + phosphate + uroporphyrin I(out)


name: cytidine(32) in tRNA + S-adenosyl-L-methionine => 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine


name: (2E)-octenoyl-[ACP] + H(+) + NADH <=> NAD(+) + octanoyl-[ACP]


name: H(+) + NADH + O2 + orcinol = 2,3,5-trihydroxytoluene + H2O + NAD(+)


name: acetyl-CoA + 3 AH2 + 18 H(+) + 10 malonyl-CoA + 8 NADPH <=> 3 A + 10 CO2 + 11 CoA + cordypyrone A + 8 H2O + 8 NADP(+)


name: PIAS4 SUMOylates PPARA with SUMO1 (Gallus gallus)


name: (24S)-hydroxycholesterol + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => (24S)-hydroxycholesterol 3-linoleoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: 2-oxoglutarate + N(6)-methyl-L-lysyl(20)-[histone H4] + O2 <=> CO2 + formaldehyde + L-lysyl(20)-[histone H4] + succinate


name: (3S,4S,5R,6R)-3,4,5,6,7-pentahydroxy-2-oxoheptanoate => 3-hydroxypyruvate + D-erythrose


name: DEGS1 dehydrogenates dihydroceramide (Sus scrofa)


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Dictyostelium discoideum)


name: a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[alpha-D-galactopyranosyl-(1->2)-alpha-D-glucopyranosyl]-sn-glycerol + H(+) + UDP


name: (9E)-octadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E,9E)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Mus musculus)


name: ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Xenopus tropicalis)


name: p190RhoGEF exchanges GTP for GDP on RHOA, activating it (Xenopus tropicalis)


name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Canis familiaris)


name: Phosphorylated MOB1A proteins associate with LATS proteins (Xenopus tropicalis)


name: 2-dehydro-3-deoxy-D-arabinonate <=> glycolaldehyde + pyruvate


name: NPAS4 stimulates RET gene expression (Homo sapiens)


name: ULK1 phosphorylates Beclin-1 (Saccharomyces cerevisiae)


name: ADP + H(+) + L-alanyl-L-glutamine(in) + phosphate => ATP + H2O + L-alanyl-L-glutamine(out)


name: 3-phenylpropanoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO2 + 4 CoA + dihydropinosylvin


name: CMP(out) + CMP-N-acetyl-beta-neuraminate(in) <=> CMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: 5-methylorsellinate + O2 + reduced [NADPH--hemoprotein reductase] <=> 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SFTPD 12mer translocates from ER membrane to extracellular region (Danio rerio)


name: an N-acylsphing-4-enine + UDP-alpha-D-glucose <=> a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP


name: (2S)-2-amino-3-methylbutan-1-ol + H2O + NAD(+) => 1-hydroxy-3-methylbutan-2-one + H(+) + NADH + NH4(+)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Xenopus tropicalis)


name: CSF2RA:CSF2RB binds SFTPs (Canis familiaris)


name: O2 + octanedioyl-CoA <=> (2E)-octenedioyl-CoA + H2O2


name: BAP1 binds BRCA1:BARD1 (Rattus norvegicus)


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate <=> 2 ADP + 2 H(+)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Caenorhabditis elegans)


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Homo sapiens)


name: CDP-D-glucose <=> CDP-4-dehydro-6-deoxy-D-glucose + H2O


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Canis familiaris)


name: AP1G2 binds HGS and CHMP2A (Canis familiaris)


name: TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Drosophila melanogaster)


name: 2 [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 => [thyroglobulin]-dehydroalanine + [thyroglobulin]-L-thyroxine + 2 H2O


name: H2O + N-tetradecanoylsphing-4-enine => sphing-4-enine + tetradecanoate


name: AMP + decanoyl-[ACP] + H(+) => decanoyl-AMP + holo-[ACP]


name: H2O + raucaffricine <=> D-glucose + vomilenine


name: MAP2K1 phosphorylates MAPK3 (Saccharomyces cerevisiae)


name: (R)-pantetheine + ATP <=> (R)-4'-phosphopantetheine + ADP + H(+)


name: a medium chain fatty acid + ATP + holo-[ACP] <=> a medium-chain fatty acyl-[ACP] + AMP + diphosphate


name: MAPKs phosphorylate PP2A (Canis familiaris)


name: (-)-alpha-gurjunene + diphosphate => (2E,6E)-farnesyl diphosphate


name: DIT and MIT combine to form triiodothyronine (Canis familiaris)


name: 2-demethylmenaquinol-8 + NADP(+) => 2-demethylmenaquinone-8 + H(+) + NADPH


name: Translocation of PLC-gamma1 to PIP2 (Mus musculus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine <=> 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Xenopus tropicalis)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Gallus gallus)


name: C-ter TLR7 dimer binds SARS-CoV-2 GU-rich ssRNA (Homo sapiens)


name: Cleavage of uracil by SMUG1 glycosylase (Mus musculus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Xenopus tropicalis)


name: 3-dehydro-L-gulonate + NAD(+) = 2,3-dioxo-L-gulonate + H(+) + NADH


name: ST6GALNAC5,6 transfer Neu5Ac to GM1b (Mus musculus)


name: TAT deaminates tyrosine (Rattus norvegicus)


name: ERBB4s80:STAT5A binds CSN2 gene promoter (Homo sapiens)


name: SALMs1-3 bind each other in cis interactions (Caenorhabditis elegans)


name: Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Canis familiaris)


name: 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H(+) => 6-deoxy-6-sulfo-D-fructose + ATP


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Drosophila melanogaster)


name: AP-2 directly binds some endocytic cargo (Schizosaccharomyces pombe)


name: OPTN binds polyUb-RIPK1 within the TNFR1 complex (Bos taurus)


name: NF1 is degraded by the proteasome (Canis familiaris)


name: (2R,3E)-phycoerythrobilin + apo-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] => phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit]


name: [Rab1 protein]-L-serine + H(+) + phosphocholine => [Rab1 protein]-O-phosphocholine-L-serine + H2O


name: EPH receptors autophosphorylate (Bos taurus)


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)


name: (S)-pinocembrin + O2 + reduced [NADPH--hemoprotein reductase] => (2S)-2-hydroxypinocembrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 3-oxo-(13Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP] => (11Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP]


name: GSTM4 dimer transfers GSH to 13(S),14(S)-epoxy-DHA to form MCTR1 (Canis familiaris)


name: ABCG4 may mediate cholesterol efflux (Gallus gallus)


name: TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Mus musculus)


name: a triacylglycerol + H2O <=> a 1,2-diacylglycerol + a fatty acid + H(+)


name: AH2 + gentamicin X2 + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + A + geneticin + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: JAK1-activated RAF1 phosphorylates MAPKs (Homo sapiens)


name: (-)-phomoidride B + H(+) + methanol + S-adenosyl-L-homocysteine => phomoidride A + S-adenosyl-L-methionine


name: PTP-RO interacts with p-c-Kit complex (Mus musculus)


name: N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-methionine = H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine


name: RAS guanyl nucleotide exchange by MET-bound GRB2:SOS1 (Xenopus tropicalis)


name: Plasma membrane resorption (Mus musculus)


name: Association of LBP with LPS (Canis familiaris)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Xenopus tropicalis)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Schizosaccharomyces pombe)


name: 2-hydroxyestrone + S-adenosyl-L-methionine <=> 2-methoxyestrone + H(+) + S-adenosyl-L-homocysteine


name: 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O <=> 2-oxopent-4-enoate + salicylate


name: Autocatalytic phosphorylation of FGFR3c (Homo sapiens)


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Rattus norvegicus)


name: Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Mus musculus)


name: 7alpha-hydroxycholest-4-en-3-one + O2 + reduced [NADPH--hemoprotein reductase] <=> 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (2S)-2-amino-2'-deoxyadenylo-succinate = dZMP + fumarate


name: PGH2 is reduced to PGF2a by AKR1C3 (Drosophila melanogaster)


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Danio rerio)


name: Fgr may phosphorylate p38 MAPK (Drosophila melanogaster)


name: Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Rattus norvegicus)


name: 2,3,5,6-tetrachlorohydroquinone + H2O + NADP(+) => 2,3,5,6-tetrachlorophenol + NADPH + O2


name: GAB1 phosphorylation by EGFR kinase (Drosophila melanogaster)


name: (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + H(+) + UDP => (5R)-5-hydroxy-L-lysyl-[collagen] + UDP-alpha-D-galactose


name: S1P hydrolyzes SREBP1A,1C,2 (Mus musculus)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[16] (Danio rerio)


name: protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity


name: Palmostatin B binds RAS depalmitoylases (Sus scrofa)


name: MSR1 (SCARA1) binds collagen (Homo sapiens)


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)


name: H2O + N-terminal L-tryptophanyl-L-alpha-aminoacyl-[peptide] => L-tryptophan + N-terminal L-alpha-aminoacyl-[peptide]


name: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Mus musculus)


name: TXLNA (IL14) binds syntaxin3 (Sus scrofa)


name: SARS-CoV-2 3CLpro dimer binds to STING (Homo sapiens)


name: RAC1:GTP binds NOX1 complex (Xenopus tropicalis)


name: (R)-glycerate(in) + H(+)(in) => (R)-glycerate(out) + H(+)(out)


name: oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor


name: AS3MT transfers CH3 from AdoMet to methylarsonite (Mus musculus)


name: a nucleoside 5'-phosphate + H(+) => a nucleoside 3',5'-cyclic phosphate + H2O


name: quillate + UDP-alpha-D-glucose = quillaic acid 28-beta-D-glucoside + UDP


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + a cardiolipin


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Danio rerio)


name: CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)


name: Squalene is oxidized to its epoxide (Saccharomyces cerevisiae)


name: glycine + hexadecanoyl-CoA => CoA + H(+) + N-hexadecanoylglycine


name: (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+) => 1,2,3-trihydroxybenzene + O2


name: RAB6:GTP displaces PAFAH1B1 from dynein:dynactin complex (Homo sapiens)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Dictyostelium discoideum)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Xenopus tropicalis)


name: a ribonucleotidyl-ribonucleotide-RNA => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA


name: D-erythrose 4-phosphate + L-erythrulose = beta-D-fructose 6-phosphate + glycolaldehyde


name: (R)-carnitine + ATP + CoA <=> (R)-carnitinyl-CoA + AMP + diphosphate


name: Extracellular BTD hydrolyses BCTN (Sus scrofa)


name: IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Bos taurus)


name: 5-hydroxymethyl-dCMP + H(+) + H2O = 5-hydroxymethyl-dUMP + NH4(+)


name: putrescine + S-adenosyl-L-methionine => H(+) + N-methylputrescine + S-adenosyl-L-homocysteine


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Saccharomyces cerevisiae)


name: SETD8 monomethylates histone H4 (Drosophila melanogaster)


name: 2-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate => 2-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: 1D-myo-inositol hexakisphosphate + H(+) + phosphate => 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O


name: (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O => (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + L-glutamate


name: p-T182 MAPKAPK5 binds DNAJB1 (Homo sapiens)


name: AH2 + alpha-N-dichloroacetyl-p-aminophenylserinol + 2 O2 => A + chloramphenicol + 2 H2O


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)


name: p-STAT5 binds the NOX4 promoter (Homo sapiens)


name: Translocation of TRAF6 to CBM complex (Bos taurus)


name: 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: malonate-semialdehyde dehydrogenase (acetylating) activity


name: ITPA hydrolyses XTP to XMP (Saccharomyces cerevisiae)


name: RAC1 and CDC42 activate PAK3 (Xenopus tropicalis)


name: ATP + pyridoxal => ADP + H(+) + pyridoxal 5'-phosphate


name: a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine => H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide


name: cholest-4-en-3-one + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (25S)-3-oxocholest-4-en-26-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: adenosine 5'-phosphosulfate + 2 glutathione => AMP + glutathione disulfide + 2 H(+) + sulfite


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Homo sapiens)


name: α2-agonists bind ADRA2A,B,C (Mus musculus)


name: adenosine 3',5'-bisphosphate + dopamine 4-O-sulfate + H(+) => 3'-phosphoadenylyl sulfate + dopamine


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Gallus gallus)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Dictyostelium discoideum)


name: IL18:IL18R1 binds IL18RAP (Xenopus tropicalis)


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + ATP <=> 3-diphospho-1D-myo-inositol 1,2,4,5-tetrakisphosphate + ADP


name: AP1G2 binds HGS and CHMP2A (Xenopus tropicalis)


name: RAP1A exchanges GDP for GTP (Sus scrofa)


name: Butyrylcholinesterase hydrolyzes acyl Ghrelin (Rattus norvegicus)


name: H2O + N(6)-glutaryl-L-lysyl-[protein] + NAD(+) => 2''-O-glutaryl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: 3-oxoisoapionate + ATP = 3-oxoisoapionate 4-phosphate + ADP + H(+)


name: 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H2O => (9Z,12Z)-octadecadienoate + a 1-acyl-sn-glycero-3-phosphoethanolamine + H(+)


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Caenorhabditis elegans)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Caenorhabditis elegans)


name: RAC3 translocates to the endoplasmic reticulum membrane (Canis familiaris)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Mus musculus)


name: a quinone + 2 H(+) + hydrogen sulfide + sulfite => a quinol + thiosulfate


name: 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Caenorhabditis elegans)


name: butanal + H2O + NAD(+) => butanoate + 2 H(+) + NADH


name: (E)-feruloyl-CoA + H2O <=> (E)-ferulate + CoA + H(+)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphocholine => 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphocholine


name: C4-dicarboxylate transmembrane transporter activity


name: dihydropyrimidine dehydrogenase (NAD+) activity


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Canis familiaris)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate <=> 10-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2-oxosuccinamate + L-glutamate => 2-oxoglutarate + L-asparagine


name: 3-hydroxy-1H-quinolin-4-one + O2 = CO + H(+) + N-formylanthranilate


name: Active PLC-gamma1 dissociates from EGFR (Xenopus tropicalis)


name: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Dictyostelium discoideum)


name: PDGF-AB clevage by Furin (Rattus norvegicus)


name: BRCA1:BARD1 heterodimer autoubiquitinates (Bos taurus)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + N(omega)-(1-hydroxy-2-oxoethyl)-L-arginyl-[protein] = glycolate + H(+) + L-arginyl-[protein]


name: a globoside Gb4Cer + UDP-alpha-D-galactose => a globoside NOR1 + H(+) + UDP


name: Polyubiquitinated NRIF migrates to the nucleus (Canis familiaris)


name: c-FOS activation by phospho ERK1/2 (Rattus norvegicus)


name: D-cellotetraono-1,5-lactone + H2O2 => D-cellotetraose + O2


name: H(+) + ilicicolin A epoxide + NADPH + O2 => 16-hydroxy-ilicicolin A epoxide + H2O + NADP(+)


name: GABRR pentamers:GABA transports extracellular Cl- to cytosol (Bos taurus)


name: (S)-2-amino-6-oxohexanoate + NH4(+) + phosphate => (5R)-5-phosphooxy-L-lysine + H2O


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Canis familiaris)


name: 3-hexadecanoyl-sn-glycero-1-phospho-(3'-hexadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol) => 2 3-hexadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol)


name: (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine <=> 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: IL35 binds IL6ST:IL6ST receptor (Canis familiaris)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + cholesterol <=> 1-hexadecanoyl-sn-glycero-3-phosphocholine + cholesteryl (9Z,12Z)-octadecadienoate


name: dTTP + 2 H2O = dTMP + 2 H(+) + 2 phosphate


name: (2E)-butenoyl-CoA + H2O => (2R)-hydroxybutanoyl-CoA


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Gallus gallus)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 <=> 11-hydroperoxy-(8Z,12E,14Z)-eicosatrienoate


name: VENTX stimulates p16-INK4A transcription (Homo sapiens)


name: p-S256-Aquaporin-2 passively transports water into cell (Drosophila melanogaster)


name: H(+) + hexadecanoyl-CoA + oxidized [electron-transfer flavoprotein] <=> (2E)-hexadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: a (2R)-2-hydroxycarboxylate + NAD(+) = a 2-oxocarboxylate + H(+) + NADH


name: p-S207 KARS1 dimer binds MITF-M:HINT1 dimer (Rattus norvegicus)


name: (3S)-hydroxydodecanedioyl-CoA + NAD(+) <=> 3-oxododecanedioyl-CoA + H(+) + NADH


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Saccharomyces cerevisiae)


name: Interleukin-27 dissociates from Interleukin-27 receptor (Sus scrofa)


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Rattus norvegicus)


name: [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O => [thyroglobulin]-3-iodo-L-tyrosine + H(+) + H2O2 + iodide


name: p62 binds ubiquitinated mitochondrial substrates (Gallus gallus)


name: BCKDK phosphorylates BCKDH (Mus musculus)


name: MAOB:FAD oxidatively deaminates TYR (Danio rerio)


name: BRAF autophosphorylates downstream of RAP1 and NGF (Rattus norvegicus)


name: acetyl-CoA + H2O = adenosine 3',5'-bisphosphate + 2 H(+) + S-acetyl-4'-phosphopantetheine


name: CoA + H(+) + octadecanoate => H2O + octadecanoyl-CoA


name: 2,4-dinitrotoluene + NADH + O2 = 4-methyl-5-nitrocatechol + NAD(+) + nitrite


name: chenodeoxycholoyl-CoA + glycine = CoA + glycochenodeoxycholate + H(+)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Dictyostelium discoideum)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate = beta-geranylfarnesene + diphosphate


name: adenosine 3',5'-bisphosphate(out) + ADP(in) => adenosine 3',5'-bisphosphate(in) + ADP(out)


name: PHF20 binds TP53 dimethylated on K370 and K382 (Homo sapiens)


name: Degradation of TGF-beta receptor complex (Caenorhabditis elegans)


name: Assembly of the destruction complex (Mus musculus)


name: acetyl-CoA + N-terminal L-alanyl-[ribosomal protein uS5] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein uS5]


name: ECE1 cleaves EDN1(53-90) (Gallus gallus)


name: 2 (2E,6E)-farnesyl diphosphate + H(+) + NADPH <=> 2 diphosphate + NADP(+) + squalene


name: CoA + NAD(+) + pentanal = H(+) + NADH + pentanoyl-CoA


name: acetyl-CoA + an aliphatic alcohol => an acetyl ester + CoA


name: Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Canis familiaris)


name: SUMOylation of XPC with SUMO1 (Plasmodium falciparum)


name: Active FLT3:p-Y GRB10:PIK3R1 binds PIK3CA (Sus scrofa)


name: Passive I- efflux mediated by SLC5A8 (Bos taurus)


name: ESPL1 (Separase) cleaves centromeric cohesin (Homo sapiens)


name: G6PC3 hydrolyzes G6P to form Glc and Pi (ubiquitous) (Mus musculus)


name: JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Rattus norvegicus)


name: an aliphatic sulfonate + H2O + 2 oxidized [4Fe-4S]-[ferredoxin] = an aldehyde + 3 H(+) + 2 reduced [4Fe-4S]-[ferredoxin] + sulfite


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Xenopus tropicalis)


name: 2 chloride + 2 FADH2 + 2 O2 + sulochrin <=> dihydrogeodin + 2 FAD + H(+) + 4 H2O


name: GGCX gamma-carboxylates 3D-F9(29-461) (pro-factor IX) (Canis familiaris)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  upon TLR7/8 or 9 activation (Homo sapiens)


name: H2O + L-mimosine <=> 3-hydroxy-4H-pyrid-4-one + NH4(+) + pyruvate


name: hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate => phosphate + S-methyl-5'-thioinosine


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + 1-O-alkyl-sn-glycero-3-phosphocholine


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + H(+) + phosphate => 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Gallus gallus)


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: 3-maleylpyruvate + H(+) => 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Rattus norvegicus)


name: 1-hexadecanoyl-2-propionyl-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + propanoate


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: (9Z)-hexadecenoate + ATP + CoA => (9Z)-hexadecenoyl-CoA + AMP + diphosphate


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Saccharomyces cerevisiae)


name: Proglucagon translocates from the ER Lumen to secretory granules (Canis familiaris)


name: p-S167-ESR1 translocates from the cytosol to the nucleus (Drosophila melanogaster)


name: Unwinding of DNA for the Nascent Transcript: Second Transition (Drosophila melanogaster)


name: (20S)-ginsenoside Rg1 + L-rhamnopyranose => (20S)-ginsenoside Re + H2O


name: Phosphorylation of PLC-gamma by p-BTK/p-SYK (Canis familiaris)


name: 2-methylhexadecanoyl-CoA + 2 H(+) + 2 malonyl-CoA <=> 6-(hexadecan-2-yl)-4-hydroxy-pyran-2-one + 2 CO2 + 3 CoA


name: 8-methylquinoline + A + H2O => 8-methylquinolin-2(1H)-one + AH2


name: hydrogencarbonate(out) + selenite(out) + Zn(2+)(out) => hydrogencarbonate(in) + selenite(in) + Zn(2+)(in)


name: Activated NTRK3 binds SRC (Mus musculus)


name: Fe(3+)(out) + L-ascorbate(in) <=> Fe(2+)(out) + H(+) + monodehydro-L-ascorbate radical(in)


name: CoA + ecdysone hexadecanoate => ecdysone + hexadecanoyl-CoA


name: IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Danio rerio)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(34-42) (Homo sapiens)


name: 2-oxo-2H-pyran-4,6-dicarboxylate + H2O <=> (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(+)


name: SLC26A4 transports I- from cytosol to extracellular region (Xenopus tropicalis)


name: ECHS1 hydrates methacrylyl-CoA (Caenorhabditis elegans)


name: ATP + ecdysone <=> ADP + ecdysone 22-phosphate + H(+)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Canis familiaris)


name: RNF144A binds PRKDC and Ubiquitin:UBE2L3 (Gallus gallus)


name: TP53 stimulates and ZNF420 inhibits TP53AIP1 expression (Homo sapiens)


name: GOT2 dimer deaminates L-Asp (Caenorhabditis elegans)


name: 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate => ATP + L-seryl-[protein]


name: a 2'-deoxyribonucleoside 5'-diphosphate + H(+) + phosphoenolpyruvate => a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate


name: Thyrotropin is a heterodimer (Sus scrofa)


name: (R)-carnitinyl-CoA + crotonobetaine => (R)-carnitine + crotonobetainyl-CoA


name: (2E,6E)-farnesyl diphosphate + H2O <=> beta-eudesmol + diphosphate


name: Transport of MHC II:Ii complex to plasma membrane (Canis familiaris)


name: beta-D-glucosaminyl-(1->4)-N-acetyl-D-glucosamine + H2O => D-glucosamine + N-acetyl-D-glucosamine


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Danio rerio)


name: 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Caenorhabditis elegans)


name: H2O + N(6)-methyl-ATP <=> diphosphate + H(+) + N(6)-methyl-AMP


name: L-serine + L-threonine => H2O + L-seryl-L-threonine


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Rattus norvegicus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Dictyostelium discoideum)


name: Cleavage of uracil by SMUG1 glycosylase (Sus scrofa)


name: Basigin binds Matrix metalloproteinase-1 (Homo sapiens)


name: beta-muricholate + lithocholoyl-CoA = beta-muricholoyl-CoA + lithocholate


name: RGGT binds the RAB-binding subunit (Caenorhabditis elegans)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Caenorhabditis elegans)


name: dihydroxyacetone phosphate + H2O2 => O2 + sn-glycerol 3-phosphate


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Bos taurus)


name: Tyrosine is hydroxylated to dopa (Bos taurus)


name: biochanin A 7-O-beta-D-glucoside 6''-O-malonate + CoA => biochanin A 7-O-beta-D-glucoside + malonyl-CoA


name: 5,10-dihydrophenazine-1,6-dicarboxylate + O2 => H2O2 + phenazine-1,6-dicarboxylate


name: SARS-CoV-2 M protein binds MAVS (Homo sapiens)


name: 2-oxoglutarate + L-asparaginyl-[ankyrin-repeat domain protein] + O2 = (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + CO2 + succinate


name: Basigin binds Matrix metalloproteinase-1 (Gallus gallus)


name: 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 8,12-diethyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: Basigin interacts with CD43 (Sus scrofa)


name: p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane (Danio rerio)


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Mus musculus)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Bos taurus)


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Caenorhabditis elegans)


name: UDP-alpha-D-galactose(in) + UDP-N-acetyl-alpha-D-glucosamine(out) => UDP-alpha-D-galactose(out) + UDP-N-acetyl-alpha-D-glucosamine(in)


name: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 <=> 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: Release of docked dopamine loaded synaptic vesicle (Mus musculus)


name: Dissociation of cytosolic HSF1:HSP90 complex (Bos taurus)


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Bos taurus)


name: ENPP7 hydrolyzes sphingomyelin (Sus scrofa)


name: 2,6-dichlorobenzoquinone + chloride + FAD + H(+) + H2O => 2,4,6-trichlorophenol + FADH2 + O2


name: 2-heptyl-4(1H)-quinolone + H2O => 1-(2-aminophenyl)decane-1,3-dione


name: myo-inositol + UDP-alpha-D-galactose <=> alpha-D-galactosyl-(1->3)-1D-myo-inositol + H(+) + UDP


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Caenorhabditis elegans)


name: Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Sus scrofa)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => diphosphate + stellata-2,6,19-triene


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Saccharomyces cerevisiae)


name: H(+) + N(6)-(dimethylallyl)adenosine 5'-phosphate + NADPH + O2 = 9-ribosyl-trans-zeatin 5'-phosphate + H2O + NADP(+)


name: TRAF1 binds TRAF2 within TNFR1 signaling complex (Homo sapiens)


name: D-glucarate(in) + H(+)(in) => D-glucarate(out) + H(+)(out)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Bos taurus)


name: DENND4s exchange GTP for GDP on RAB10 (Drosophila melanogaster)


name: 25-hydroxyvitamin D3 sulfate(out) + n H(+)(out) => 25-hydroxyvitamin D3 sulfate(in) + n H(+)(in)


name: Arachidonate is epoxidated to 8,9-EET by CYP(5) (Rattus norvegicus)


name: FABP5:atRA translocates from cytosol to nucleoplasm (Bos taurus)


name: The Kiss receptor GPR54 binds kisspeptin (Danio rerio)


name: dioscin + 2 H2O <=> diosgenin 3-O-beta-D-glucoside + 2 L-rhamnopyranose


name: D-serine + phosphate => H2O + O-phospho-D-serine


name: ATP + xylitol <=> ADP + H(+) + xylitol 5-phosphate


name: Adenylate cyclase converts ATP into cyclic AMP (Gallus gallus)


name: JNK phosphorylates BIM, BAD and other targets (Mus musculus)


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Bos taurus)


name: N-hexanoyl-sphing-4-enine-1-phosphocholine <=> choline + N-(hexanoyl)-sphing-4-enine-1,3-cyclic phosphate


name: ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Homo sapiens)


name: (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate = (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: (indol-3-yl)acetate + H(+) = CO2 + skatole


name: H(+)(out) + L-threonine(out) => H(+)(in) + L-threonine(in)


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Schizosaccharomyces pombe)


name: L-glutamine(104)-[histone H2A] + S-adenosyl-L-methionine => H(+) + N(5)-methyl-L-glutamine(104)-[histone H2A] + S-adenosyl-L-homocysteine


name: Ubiquitination of SKI/SKIL by RNF111/SMURF2 (Homo sapiens)


name: DP1 receptor can bind PGD2 (Mus musculus)


name: 2-methylhexadecanoate + ATP + CoA = 2-methylhexadecanoyl-CoA + AMP + diphosphate


name: S-adenosyl-L-methionine + uridine(2843) in 25S rRNA <=> H(+) + N(3)-methyluridine(2843) in 25S rRNA + S-adenosyl-L-homocysteine


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Gallus gallus)


name: (9Z)-octadecenoate + glycerol + H(+) => (9Z-octadecenoyl)-glycerol + H2O


name: beta-D-glucose + D-glucose => D-cellobiose + H2O


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexanoyl-sn-glycero-3-phosphocholine <=> 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine


name: holo-FDPS dimer binds NBPs (Plasmodium falciparum)


name: Lactoperoxidase (LPO) produces OSCN- (Bos taurus)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Mus musculus)


name: 3-(2-aminophenyl)succinyl-CoA + succinate => (2-aminophenyl)succinate + succinyl-CoA


name: Aquaporins passively transport water into cells (Bos taurus)


name: ERK1/2 phosphorylates MSK1 (Homo sapiens)


name: TCN1 binds correnoids in the circulation (Xenopus tropicalis)


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Gallus gallus)


name: an acyl-CoA(out) + ATP + H2O = ADP + an acyl-CoA(in) + H(+) + phosphate


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Caenorhabditis elegans)


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Bos taurus)


name: 2-cis-(+)-abscisate + UDP-alpha-D-glucose <=> beta-D-glucopyranosyl cis-(+)-abscisate + UDP


name: Binding of TFIIE to the growing preinitiation complex (Gallus gallus)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Mus musculus)


name: n adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate + 2 H(+) => n 3'-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate


name: ADP + H(+) + sphinganine 1-phosphate => ATP + sphinganine


name: (R)-pantothenate(out) + 2 Na(+)(out) => (R)-pantothenate(in) + 2 Na(+)(in)


name: apulose + ATP => ADP + apulose 4-phosphate + H(+)


name: WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Sus scrofa)


name: Activation of ISG15 by UBA7 E1 ligase (Plasmodium falciparum)


name: Fibronectin degradation by MMP14 (Xenopus tropicalis)


name: CBL ubiquitinates PI3K (Caenorhabditis elegans)


name: 1-hydroxyphenazine + CO2 + H2O + NAD(+) => 2 H(+) + NADH + O2 + phenazine-1-carboxylate


name: (indol-3-yl)butanoate + ATP + L-cysteine = (indol-3-yl)butanoyl-L-cysteine + AMP + diphosphate + H(+)


name: Phosphorylation of Cyclin B1 in the CRS domain (Xenopus tropicalis)


name: ATP + D-erythronate => 4-phospho-D-erythronate + ADP + H(+)


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Rattus norvegicus)


name: beta-nicotinamide D-riboside(in) = beta-nicotinamide D-riboside(out)


name: 2-nitroglycerol + NADP(+) + nitrite => 1,2-dinitroglycerol + NADPH


name: SFTPD gene produces SFTPD protein (Homo sapiens)


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Caenorhabditis elegans)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Homo sapiens)


name: Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Bos taurus)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)


name: (E)-4-coumarate + H2O <=> 3-hydroxy-3-(4-hydroxyphenyl)propanoate


name: (2R,3S)-3-isopropylmalate + NAD(+) <=> (2S)-2-isopropyl-3-oxosuccinate + H(+) + NADH


name: (2R)-2-phosphoglycerate + H2O => (R)-glycerate + phosphate


name: 4-aminobutanoate(out) + n H(+)(in) <=> 4-aminobutanoate(in) + n H(+)(out)


name: 6-methylsalicylate + H(+) = 3-methylphenol + CO2


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Gallus gallus)


name: RABGGTA and RABGGTB bind (Canis familiaris)


name: STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Sus scrofa)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + H(+) => a ribonucleotidyl-ribonucleotide-RNA + H2O


name: coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: Transfer of Ub from E2 to substrate and release of E2 (Xenopus tropicalis)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Mus musculus)


name: a 1,3-diacylglycerol + an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base => a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base


name: Interleukin-12 dissociates from Interleukin-12 receptor (Mus musculus)


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Sus scrofa)


name: PIAS4 SUMOylates RNF168 with SUMO1 (Mus musculus)


name: factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) (Gallus gallus)


name: Assembly of IFT A complex (Homo sapiens)


name: a fatty acid + an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: MADD exchanges GTP for GDP on RAB27 (Gallus gallus)


name: [DsrC protein]-disulfide + 3 AH2 + 2 H(+) + sulfite => [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 3 A + 3 H2O


name: GLO1 dimer:2xZn2+ transforms MGXL and GSH to (R)-S-LGSH (Drosophila melanogaster)


name: 3-methylbutanoate + ATP + CoA <=> 3-methylbutanoyl-CoA + AMP + diphosphate


name: 2-dehydro-3-deoxy-L-arabinonate <=> glycolaldehyde + pyruvate


name: GPR31 is a receptor for 12(S)-HETE (Canis familiaris)


name: C3d-complexed antigen binds to complement receptor (Bos taurus)


name: (2E)-octenoyl-CoA + H(+) + NADPH = NADP(+) + octanoyl-CoA


name: PCSK9:LDLR bind to Clathrin (Mus musculus)


name: Hemoglobin A is protonated and carbamated causing release of oxygen (Rattus norvegicus)


name: Acyl Ghrelin and C-Ghrelin are secreted (Bos taurus)


name: Interaction of Nectins with Afadin (Drosophila melanogaster)


name: benzylamine + pyruvate => benzaldehyde + L-alanine


name: ATM phosphorylates HERC2 (Rattus norvegicus)


name: (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) => (2Z,4Z)-2-hydroxyhepta-2,4-diene-1,7-dioate + CO2


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Rattus norvegicus)


name: CRK,CRKL recruits RAC1 GEF to activated MET (Canis familiaris)


name: a dicarboxylate(in) + estrone 3-sulfate(out) <=> a dicarboxylate(out) + estrone 3-sulfate(in)


name: D-glucose + NADP(+) <=> 6-dehydro-D-glucose + H(+) + NADPH


name: 7,9,9'-tri-cis-neurosporene + a quinol => 9,9'-di-cis-zeta-carotene + a quinone


name: type II transforming growth factor beta receptor binding


name: SLC27A2-mediated ligation of peroxisomal fatty acid and CoASH (Drosophila melanogaster)


name: TGFBR3 translocation to plasma membrane (Mus musculus)


name: (S)-2-ureidoglycine + glyoxylate => glycine + N-carbamoyl-2-oxoglycine


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Bos taurus)


name: KCNH2:KCNE transport K+ from cytosol to extracellular region (Rattus norvegicus)


name: 4-(2,4-dichlorophenoxy)butanoate + ATP + L-glutamine => 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: Activated RHOA, RHOG, RAC1 and CDC42 bind KTN1 (kinectin) (Gallus gallus)