name: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O <=> 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate


name: O2 + reduced [NADPH--hemoprotein reductase] + trans-5-O-(4-coumaroyl)-D-quinate = 5-O-[(E)-caffeoyl]-D-quinate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Mus musculus)


name: EGFR binds EGF ligand (Xenopus tropicalis)


name: geranylgeranyl-bacteriochlorophyllide a + 3 H(+) + 3 NADPH => bacteriochlorophyll a + 3 NADP(+)


name: EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Schizosaccharomyces pombe)


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Mus musculus)


name: ADP + D-glucose <=> AMP + D-glucose 6-phosphate + H(+)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  upon TLR7/8 or 9 activation (Gallus gallus)


name: 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA


name: 9alpha,11alpha-methylene thromboxane A2 + O2 + reduced [NADPH--hemoprotein reductase] = 18-hydroxy-9alpha,11alpha-methylene thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H(+) + NADH + pregn-5-ene-3,20-dione => NAD(+) + pregnenolone


name: a fatty acid + L-isoleucine => an N-(fatty acyl)-L-isoleucine + H2O


name: PAN2-PAN3 complex partially deadenylates mRNA (Mus musculus)


name: (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate = plasmodiophorol A


name: Association of procollagen type XVII (Bos taurus)


name: Pregnenolone is dehydrogenated to form pregn-5-ene-3,20-dione (Rattus norvegicus)


name: 5-(methylsulfanyl)-D-ribose + adenine => H2O + S-methyl-5'-thioadenosine


name: docosanoate + glycine = H2O + N-docosanoylglycine


name: ZDHHC7, ZDHHC21 palmitoylate ESR1 (Homo sapiens)


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Mus musculus)


name: holo-[peptidyl-carrier protein] + L-seryl-5'-AMP => AMP + L-seryl-[peptidyl-carrier protein]


name: p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Drosophila melanogaster)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Mus musculus)


name: MRN complex binds DNA double strand breaks (Drosophila melanogaster)


name: ABC7, mABC1 and mABC2 mediate heme transport (Schizosaccharomyces pombe)


name: (Z)-alpha-bisabolene + diphosphate => (2Z,6E)-farnesyl diphosphate


name: a fatty acid + ATP <=> a fatty acyl phosphate + ADP


name: 2-oxoglutarate + dTDP-3-amino-3,6-dideoxy-alpha-D-glucose = dTDP-3-dehydro-6-deoxy-alpha-D-glucose + L-glutamate


name: CoA + glutathione disulfide => CoA-glutathione + glutathione


name: Autocatalytic phosphorylation of FGFR2b (Bos taurus)


name: D-cellobiose + phosphate => alpha-D-glucose 1-phosphate + D-glucose


name: Glypican-1 (GPC1) binds SLIT2 (Homo sapiens)


name: DNA-(apurinic or apyrimidinic site) endonuclease activity


name: Prolactin receptor is internalized (Rattus norvegicus)


name: BCL2 binds BCL2 antagonists (Xenopus tropicalis)


name: group A colicin transmembrane transporter activity


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Canis familiaris)


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Canis familiaris)


name: RPE dimers isomerise RU5P to XY5P (Canis familiaris)


name: VTN binds Plasminogen activator inhibitor- 1 (Danio rerio)


name: FKBP1A binds sirolimus (Saccharomyces cerevisiae)


name: OPTN binds TBK1 within the activated TLR4 complex (Bos taurus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-glycerol + CDP-ethanolamine <=> 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Gallus gallus)


name: Inactive G alpha (z) reassociates with G beta:gamma (Xenopus tropicalis)


name: L-seryl-[protein] + pentanoyl-CoA => CoA + O-pentanoyl-L-seryl-[protein]


name: (1R,2R,3R)-prephytoene diphosphate + H(+) + NADPH = all-trans-lycopaoctaene + diphosphate + NADP(+)


name: Association of GABA B receptor with G protein beta-gamma subunits (Drosophila melanogaster)


name: glutamate + acetyl CoA => N-acetyl glutamate + CoA (Rattus norvegicus)


name: Resynthesis of excised residue by POLB (Homo sapiens)


name: Oxysterol binds to the ABCA1 gene:NR1H2,3:RXR:NCOR:GPS2:TBL1:HDAC3 complex (Drosophila melanogaster)


name: a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GD2 (d18:1(4E)) + H(+) + UDP


name: a (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Gallus gallus)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)


name: C5a receptor binds C5a anaphylatoxin (Gallus gallus)


name: FAD attaches to SDHA (Dictyostelium discoideum)


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Dictyostelium discoideum)


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Rattus norvegicus)


name: LRTOMT transfers Met to DA, forming 3MT (Gallus gallus)


name: Initial activation of proMMP1 (Caenorhabditis elegans)


name: (+)-copalyl diphosphate + H2O => (+)-copalol + diphosphate


name: beta-D-fructose 6-phosphate + UDP-alpha-D-glucose = H(+) + sucrose 6(F)-phosphate + UDP


name: 11beta,17beta-dihydroxyandrost-4-ene-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + reduced [NADPH--hemoprotein reductase] + testosterone


name: BTK in active Gq-BTK complex is activated (Sus scrofa)


name: AGK:Mg2+ phosphorylates MAG, DAG (Rattus norvegicus)


name: H2O + NAD(+) + pentanal <=> 2 H(+) + NADH + pentanoate


name: 8,20-dihydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 8-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase]


name: chenodeoxycholate + O2 + reduced [NADPH--hemoprotein reductase] = alpha-muricholate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PIAS1 SUMOylates NR3C2 (Mineralcorticoid Receptor) with SUMO1 (Mus musculus)


name: bicyclomycin transmembrane transporter activity


name: hyodeoxycholate + UDP-alpha-D-glucuronate = H(+) + hyodeoxycholate 6-O-(beta-D-glucuronate) + UDP


name: USP3,SAGA deubiquitinate Histone H2A,H2B (Bos taurus)


name: CDP-alpha-D-abequose + NADP(+) => CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H(+) + NADPH


name: ATP + ethylamine + L-glutamate <=> ADP + H(+) + N(5)-ethyl-L-glutamine + phosphate


name: D-serine(in) + Na(+)(in) <=> D-serine(out) + Na(+)(out)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Homo sapiens)


name: AGT(34-41) binds to AGTR2 (Mus musculus)


name: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + 2 H(+) + NADH => 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H2O + NAD(+)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Rattus norvegicus)


name: ADP + H(+) + phosphate + xanthine(in) => ATP + H2O + xanthine(out)


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Dictyostelium discoideum)


name: eicosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> 2-hydroxyeicosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Mus musculus)


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex  (Mus musculus)


name: Elastin degradation by elastin-degrading extracellular proteinases (Canis familiaris)


name: beta-alanine + 2 H(+) + NADH => 3-aminopropanal + H2O + NAD(+)


name: betaenone C + 3 H2O + 3 NADP(+) => dehydroprobetaenone I + 3 H(+) + 3 NADPH + 3 O2


name: a cardiolipin + H2O = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H(+)


name: PLB1 hydrolyses RPALM to atROL (Drosophila melanogaster)


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Sus scrofa)


name: Frataxin binds iron (Drosophila melanogaster)


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] = 8-epi-inunolide + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: TBC RabGAPs accelerate GTP hydrolysis by RAB35 (Danio rerio)


name: (12R,13S)-epoxy-(9Z)-octadecenoate + O2 = (12R,13S)-epoxy-(10R)-hydroperoxy-(8E)-octadecenoate


name: N-(8'-oxogeranyl)-L-glutamate + O2 + reduced [NADPH--hemoprotein reductase] = 2 H(+) + H2O + N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase]


name: beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-beta-L-fucose <=> alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: 2-oxoglutarate + O2 + penicillin N = CO2 + deacetoxycephalosporin C + H2O + succinate


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 = 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Rattus norvegicus)


name: [protein]-disulfide + an alcohol + H2O => [protein]-dithiol + a hydroperoxide


name: protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity


name: (S)-carnitine(in) + Na(+)(in) => (S)-carnitine(out) + Na(+)(out)


name: an N-(fatty acyl)-L-leucine + H2O = a fatty acid + L-leucine


name: RHOG translocates to the ER membrane (Drosophila melanogaster)


name: 2,4,5-trihydroxyphenylacetate + H2O + NADP(+) => 3,4-dihydroxyphenylacetate + H(+) + NADPH + O2


name: Alpha1-Microglobulin binds heme (Xenopus tropicalis)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine <=> di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Bos taurus)


name: Recruitment of GRB2:SOS to p-5Y-LAT (Rattus norvegicus)


name: Heterotrimeric G protein (i) binds membrane-associated ESRs:ESTG (Sus scrofa)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Gallus gallus)


name: LNK binds to p-KIT and inhibit downstream signaling (Canis familiaris)


name: acetyl-CoA + D-alanine => (2R)-2-amino-4-oxopentanoate + CoA


name: a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine => a lipid A disaccharide + H(+) + UDP


name: Insertion of MHC II:Ii complex in to the plasma membrane (Bos taurus)


name: a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: Frataxin transfers Fe2+ to ACO2 (Mus musculus)


name: (S)-2-hydroxyglutarate + GDP-D-glycero-4-keto-alpha-D-lyxo-heptose => 2-oxoglutarate + GDP-D-glycero-alpha-D-manno-heptose


name: IL12B:IL12B translocates from ER lumen to the extracellular region (Homo sapiens)


name: NIPAs transport Mg2+ from extracellular region to cytosol (Rattus norvegicus)


name: 2-hydroxyoctadecanal + phosphoethanolamine => 4-hydroxyeicosasphinganine 1-phosphate


name: 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(out) + glutarate(in) <=> 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(in) + glutarate(out)


name: ethanol + H(+) + hexadecanoate => ethyl hexadecanoate + H2O


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Homo sapiens)


name: benzyl alcohol + cetraxate + H(+) => benzyl cetraxate + H2O


name: BIL:ALB scavenges O2.- (Rattus norvegicus)


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Mus musculus)


name: dihydrodigoxigenin + 2 Fe(III)-[cytochrome c] => digoxigenin + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: dodecanoyl-CoA + L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] => CoA + H(+) + N(6)-dodecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein]


name: 1-naphthaldehyde + H2O + O2 <=> 1-naphthoate + H(+) + H2O2


name: IL21 binds IL21R:JAK1 (Canis familiaris)


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Homo sapiens)


name: HMIT co-transports myo-inositol with a proton (Rattus norvegicus)


name: O2 + reduced [NADPH--hemoprotein reductase] + thromboxane A2 => 18-hydroxy-thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PLOD3 binds Lysyl hydroxylated collagen propeptides (Canis familiaris)


name: 5,10-dihydrophenazine-1,6-dicarboxylate + O2 = H2O2 + phenazine-1,6-dicarboxylate


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)


name: alpha-D-mannose 1-phosphate + GDP-alpha-D-glucose => alpha-D-glucose 1-phosphate + GDP-alpha-D-mannose


name: ILF3 and HOXC8 bind CDH11 gene promoter (Homo sapiens)


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Mus musculus)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Saccharomyces cerevisiae)


name: phosphotransferase activity, nitrogenous group as acceptor


name: "Phosphotransferases with a nitrogenous group as acceptor"


name: ATP + H2O + taurochenodeoxycholate(in) => ADP + H(+) + phosphate + taurochenodeoxycholate(out)


name: cyclomaltodextrin + H2O => linear maltodextrin


name: H2O + S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] = H(+) + S-disulfanyl-L-cysteinyl-[SoxY protein] + sulfate


name: 1-decanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-decanoyl-sn-glycero-3-phosphate + choline + H(+)


name: 2 H(+) + O2 + rifamycin B => H2O2 + rifamycin O


name: HDAC3 containing complexes deacetylate histone (Saccharomyces cerevisiae)


name: Formation of CDK4/6:CCND complexes (Canis familiaris)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Sus scrofa)


name: a (3R)-hydroxyacyl-[ACP] + UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose <=> a UDP-2-acetamido-3-{[(3R)-3-hydroxyacyl]amino}-2,3-dideoxy-alpha-D-glucopyranose + H(+) + holo-[ACP]


name: oxLDL:CD36 binds TLR4:TLR6 (Mus musculus)


name: [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine + propane-1,3-diamine => [deoxyhypusine synthase]-L-lysine + dehydrospermidine


name: Antizyme OAZ binds to Ornithine decarboxylase (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phosphocholine + cholesterol <=> (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: ISGylation of host protein filamin B (Bos taurus)


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + sphing-4-enine => 2 Fe(III)-[cytochrome b5] + 2 H2O + sphinga-4E,14Z-dienine


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Drosophila melanogaster)


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine


name: RAC1 and CDC42 activate PAK1 (Bos taurus)


name: 2xPDKX:2xZn2+ phosphorylates PDX (Dictyostelium discoideum)


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Bos taurus)


name: (24R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (24R)-7alpha-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: DENND1s exchange GTP for GDP on RAB35 (Mus musculus)


name: Interaction of DAP12 and TREM1 (Homo sapiens)


name: Type B histone acetlytransferase complex acetylates histone H4 (Saccharomyces cerevisiae)


name: 3-methylbutanoate + 2 H(+) + NADH => 3-methylbutanal + H2O + NAD(+)


name: HLCS biotinylates 6xMCCC1:6xMCCC2 (Bos taurus)


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Gallus gallus)


name: IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)


name: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate


name: Aquaporin-1 passively transports water into cell (Dictyostelium discoideum)


name: diphosphate + ent-manool => ent-copalyl diphosphate + H2O


name: ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Sus scrofa)


name: Interaction of APS and p-KIT (Xenopus tropicalis)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Type XII and XIV collagens associate with type I and type II fibrils (Sus scrofa)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Caenorhabditis elegans)


name: a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O => a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: DHPS tetramer synthesizes Dhp-K50-EIF5A from EIF5A and spermidine (Dictyostelium discoideum)


name: 3-methylbutanal + H2O + NAD(+) => 3-methylbutanoate + 2 H(+) + NADH


name: ANKH transports PPi from cytosol to extracellular region (Xenopus tropicalis)


name: 3-methylxanthine + formaldehyde + H2O + NADP(+) => H(+) + NADPH + O2 + theophylline


name: (9Z,12Z)-octadecadienoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA


name: MBTPS2 (S2P) cleaves CREB3L3 (Caenorhabditis elegans)


name: alpha-D-ribose 1-phosphate + urate => phosphate + urate D-ribonucleoside


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Sus scrofa)


name: geranylgeranyl diphosphate = diphosphate + fusicocca-2,10(14)-diene


name: Degradation of multiubiquitinated cell cycle proteins (Canis familiaris)


name: n H(+)(in) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(in) => n H(+)(out) + N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(out)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphate => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA


name: SUMOylation of NR1I2 with SUMO3 (Sus scrofa)


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Caenorhabditis elegans)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Dictyostelium discoideum)


name: NADP(+) + prostaglandin F2alpha <=> H(+) + NADPH + prostaglandin E2


name: LIG1 bound to APEX1 and PCNA ligates SSB (Canis familiaris)


name: MLCL is acylated to CL by HADH (IM) (Drosophila melanogaster)


name: a 4'-hydroxyflavanone + S-adenosyl-L-methionine <=> a 4'-methoxyflavanone + H(+) + S-adenosyl-L-homocysteine


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)


name: D-serine(in) + L-glutamine(out) + Na(+)(out) <=> D-serine(out) + L-glutamine(in) + Na(+)(in)


name: GAR + 10-Formyl-THF => FGAR + THF (Caenorhabditis elegans)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: (4-hydroxyphenyl)acetaldehyde + H2O + NAD(+) <=> 4-hydroxyphenylacetate + 2 H(+) + NADH


name: L-erythrulose 1-phosphate => D-erythrulose 4-phosphate


name: 2-amino-4-hydroxypteridine + H(+) + H2O <=> 2,4-dihydroxypteridine + NH4(+)


name: Association of Nek2A with MCC:APC/C (Drosophila melanogaster)


name: CLK:CYC heterodimer dissociates from per, tim, vri, and Pdp1 genes (Drosophila melanogaster)


name: laricitrin + S-adenosyl-L-methionine <=> 3,3'-O-dimethylmyricetin + H(+) + S-adenosyl-L-homocysteine


name: SCF-FBXL7 ubiquitinates AURKA (Canis familiaris)


name: p-S133 CREB1, LYL1 and EP300 bind the ID1 and ID3 genes (Homo sapiens)


name: (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+)


name: aryl-aldehyde dehydrogenase (NAD+) activity


name: ADP + H(+) + N-acetyl-L-aspartate(out) + phosphate => ATP + H2O + N-acetyl-L-aspartate(in)


name: Creatine transport across the plasma membrane (Canis familiaris)


name: RHOA:GTP binds RHPN1 or RHPN2 (Rattus norvegicus)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Bos taurus)


name: PAK2 phosphorylates myosin regulatory light chain (MRLC) (Dictyostelium discoideum)


name: Complement factor B binds to the hydrolyzed form of C3 (Gallus gallus)


name: glycyl-sarcosine(out) + H(+)(out) <=> glycyl-sarcosine(in) + H(+)(in)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Bos taurus)


name: 12-phosphooxy-(9E)-octadecenoate + H2O <=> 12-hydroxy-(9E)-octadecenoate + phosphate


name: 2-methyl-3-oxopropanoate + H(+) + NADH => 3-hydroxy-2-methylpropanoate + NAD(+)


name: MDM2 forms homo- or heterodimers (Canis familiaris)


name: gonadotropin-releasing hormone receptor binding


name: ATP + H2O + hexacosanoate(in) = ADP + H(+) + hexacosanoate(out) + phosphate


name: an N(1)-methyladenosine in tRNA + H(+) + S-adenosyl-L-homocysteine => an adenosine in tRNA + S-adenosyl-L-methionine


name: diphosphate + L-threonyl-5'-AMP => ATP + L-threonine


name: gamma-secretase cleaves the p75NTR transmembrane domain (Xenopus tropicalis)


name: Integrator complex processes the 3' end of snRNA (Gallus gallus)


name: PP2A dephosphorylates p-RHO to RHO (Caenorhabditis elegans)


name: SERPINB13 gene expression is inhibited by RUNX1:CBFB (Homo sapiens)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Homo sapiens)


name: Phosphorylation of L1 by ERK (Canis familiaris)


name: CLAT:AP1:CLVS bind PI(3,5)P2 (Xenopus tropicalis)


name: Autocatalytic phosphorylation of FGFR2b (Drosophila melanogaster)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Sus scrofa)


name: ZDHHC7, ZDHHC21 palmitoylate ESR1 (Xenopus tropicalis)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Homo sapiens)


name: 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + NADH => 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + NAD(+)


name: L-galactose + NAD(+) => H(+) + L-galactono-1,4-lactone + NADH


name: an acylcholine + H2O <=> a carboxylate + choline + H(+)


name: D-kanosamine 6-phosphate + H2O => kanosamine + phosphate


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphinganine + H2O = beta-D-glucose + N-hexadecanoylsphinganine


name: (2S,4S)-2-amino-4-[(3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl]-4-hydroxybutanoyl-[peptidyl-carrier protein] + H2O2 => (2S,4S,5S)-2-amino-6-(3,4-dihydroxyphenyl)-4-hydroxy-5-(methylamino)hexanoyl-[peptidyl-carrier protein] + O2


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Rattus norvegicus)


name: dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O


name: Phosphorylation of L1 by CK-II (Homo sapiens)


name: Tetrastatin binds integrin alphaVbeta3 (Mus musculus)


name: SAR1 Activation And Membrane Binding (Homo sapiens)


name: H(+) + NADPH + UDP-4-dehydro-beta-L-rhamnose => NADP(+) + UDP-beta-L-rhamnose


name: RBKS phosphorylates ribose to R5P (Caenorhabditis elegans)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[15] (Bos taurus)


name: p-S857 NCOA3 binds ETV4 (Rattus norvegicus)


name: H(+) + isopimara-7,15-dienol + NADPH + O2 <=> 2 H2O + isopimara-7,15-dienal + NADP(+)


name: 3-hydroxy-2-methyl-1H-quinolin-4-one + O2 <=> CO + H(+) + N-acetylanthranilate


name: Phosphorylation of CRMPs by Cdk5 (Danio rerio)


name: 4-hydroxybutanoyl-CoA <=> (2E)-butenoyl-CoA + H2O


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Xenopus tropicalis)


name: a 2,4-dihydroxypteridine + NH4(+) => a 2-amino-4-hydroxypteridine + H(+) + H2O


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Rattus norvegicus)


name: Release of acetylcholine at the synapse (Sus scrofa)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Saccharomyces cerevisiae)


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Schizosaccharomyces pombe)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Canis familiaris)


name: CDKN1A (p21) gene expression is positively regulated by RUNX3 and ZFHX3 (Homo sapiens)


name: The receptor:G-protein complex  binds GTP (Bos taurus)


name: CYP2D6 4-hydroxylates debrisoquine (Canis familiaris)


name: IFN alpha/beta binds to IFNAR2 (Rattus norvegicus)


name: RAB43 hydrolyses GTP (Schizosaccharomyces pombe)


name: NAA translocates from mitochondrial matrix to cytosol (Homo sapiens)


name: Caspase 3-mediated cleavage of DFF45 (117) (Gallus gallus)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Homo sapiens)


name: 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose => 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP


name: ALAD condenses 2 dALAs to form PBG (Danio rerio)


name: ROBOs bind keratan sulfate (Homo sapiens)


name: NADP(+) + pentan-2-one = (E)-pent-3-en-2-one + H(+) + NADPH


name: H2O + N-(hexadecanoyl)-sphing-4-enine-1-phosphocholine <=> H(+) + N-hexadecanoylsphing-4-enine + phosphocholine


name: Activation of Rac1 by pVav1 (Mus musculus)


name: 19-oxo-androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] = estrone + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SLIT2-bound ROBO1 binds MYO9B (Bos taurus)


name: H2O + propanamide => NH4(+) + propanoate


name: an S-alkyl-L-cysteine S-oxide => 2-aminoprop-2-enoate + an S-alkyl sulfenate


name: chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate


name: Caspase mediated cleavage of APC (Mus musculus)


name: 2-acyl LPE is acylated to PE by LPEAT (Sus scrofa)


name: H2O + NADP(+) + yersinopine <=> (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + H(+) + NADPH + pyruvate


name: IL12 bound to IL12R internalises (Bos taurus)


name: cytidine(839) in 12S rRNA + S-adenosyl-L-methionine <=> H(+) + N(4)-methylcytidine(839) in 12S rRNA + S-adenosyl-L-homocysteine


name: H(+) + H2O2 + vanillate => H2O + O2 + vanillin


name: (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(11Z,14Z)-eicosadienoyl-CoA + NADP(+)


name: SLC17A3-1 cotransports extracellular Na+ and Pi to cytosol (Drosophila melanogaster)


name: (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate => (9Z,12Z)-octadecadienoate + O2


name: RAC1 binds effectors at the plasma membrane (Rattus norvegicus)


name: Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (Homo sapiens)


name: DDX41 ubiquitination by TRIM21 (Sus scrofa)


name: (+)-exo-beta-bergamotene + 3 O2 + 2 reduced [NADPH--hemoprotein reductase] = 5-dehydro-6-demethoxyfumagillol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 28-nortyphasterol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => 6-deoxo-28-nortyphasterol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Xenopus tropicalis)


name: 4-hydroxylamino-2,6-dinitrotoluene + H(+) + NADPH = 4-amino-2,6-dinitrotoluene + H2O + NADP(+)


name: Conjugation of SUMO2 to UBA2:SAE1 (Homo sapiens)


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Drosophila melanogaster)


name: E2F1 binds the RRM2 gene promoter (Homo sapiens)


name: 8-oxo-GDP + H2O = 8-oxo-GMP + H(+) + phosphate


name: ROS oxidize thioredoxin and activate MAP3K5 (Saccharomyces cerevisiae)


name: ATP + D-glycero-alpha-D-manno-heptose 7-phosphate = ADP + D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + H(+)


name: NME1,2 hexamers phosphorylate RBV-DP (Caenorhabditis elegans)


name: SUMOylation of Histone H4 with SUMO3 (Bos taurus)


name: 2 H(+) + hexadecanoyl-[ACP] + 2 NADPH <=> hexadecan-1-ol + holo-[ACP] + 2 NADP(+)


name: GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG (Homo sapiens)


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) = 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: "Acid--alcohol ligases (ester synthases)"


name: demethylphylloquinone + H(+) + NADPH <=> demethylphylloquinol + NADP(+)


name: Recruitment of clathrin coated vesicle by Ii (Homo sapiens)


name: eriodictyol-7-O-beta-D-glucoside + H2O => (S)-eriodictyol + beta-D-glucose


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Gallus gallus)


name: H2O + tetradecamide <=> NH4(+) + tetradecanoate


name: H(+) + mycinamicin IV + S-adenosyl-L-homocysteine => mycinamicin III + S-adenosyl-L-methionine


name: Co(I)-[quaternary-amine-specific corrinoid protein] + H(+) + L-proline betaine => methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + N-methyl-L-proline


name: Defective EXT2 (in EXT1:EXT2) does not transfer GlcNAc to heparan (Homo sapiens)


name: CDK1 phosphorylates NUP98 (Xenopus tropicalis)


name: apo-[aequorin]--coelenterazine + O2 <=> [aequorin]


name: STAT1,STAT3,STAT6 phosphorylation (Mus musculus)


name: HNF6-dependent synthesis of ONECUT3 protein during morphogenesis (Homo sapiens)


name: (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: NCOA3 binds ESR1:estrogen:TFGA gene (Mus musculus)


name: ACAD11 dehydrogenates BH-CoA (Danio rerio)


name: butan-1-ol + NAD(+) => butanal + H(+) + NADH


name: 4-methyl-6-nitrocatechol + NAD(+) + nitrite => 3,4-dinitrotoluene + NADH + O2


name: factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) (Mus musculus)


name: G-protein beta-gamma subunits rebind the alpha-GDP subunit (Mus musculus)


name: The p75NTR C-terminal fragment enters endosomes (Danio rerio)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Canis familiaris)


name: H(+) + N-terminal N,N,N-trimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Drosophila melanogaster)


name: columbamine + S-adenosyl-L-methionine => H(+) + palmatine + S-adenosyl-L-homocysteine


name: H2O + L-glutaminyl-[protein] <=> L-glutamyl-[protein] + NH4(+)


name: L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-methionine => 2 H(+) + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + 2 S-adenosyl-L-homocysteine


name: Phosphorylated MAPKs translocate into the nucleus (Plasmodium falciparum)


name: [(1->2)-beta-D-glucosyl](n-2) + sophorose => [(1->2)-beta-D-glucosyl](n) + H2O


name: (+-)-pavine + S-adenosyl-L-methionine = H(+) + N-methylpavine + S-adenosyl-L-homocysteine


name: CR:atREs binds apoE and HSPG (Bos taurus)


name: (E)-hept-2-enal + H2O + NAD(+) <=> (E)-hept-2-enoate + 2 H(+) + NADH


name: a (2E)-enoyl-CoA + FADH2 => a 2,3-saturated acyl-CoA + FAD + H(+)


name: oxidoreductase activity, acting on a sulfur group of donors


name: benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Bos taurus)


name: N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine = H(+) + N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: H2O + L-tryptophan + NADP(+) <=> H(+) + indole-3-pyruvate + NADPH + NH4(+)


name: 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-glucose => 3''-deamino-3''-hydroxykanamycin X + H(+) + UDP


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Canis familiaris)


name: p-S62-ARPP19/p-S67-ENSA binds PP2A-PPP2R2D (Homo sapiens)


name: NOTCH3 coactivator complex binds WWC1 (Kibra) gene promoter (Homo sapiens)


name: DHF is reduced to tetrahydrofolate (THF) (Bos taurus)


name: H(+) + NADH + uridine(20) in tRNA => 5,6-dihydrouridine(20) in tRNA + NAD(+)


name: (R)-lipoate(out) + 2 Na(+)(out) <=> (R)-lipoate(in) + 2 Na(+)(in)


name: SPP1 (osteopontin) binds integrin alpha5beta1, alpha9beta1 (Danio rerio)


name: HLTF polyubiquitinates monoubiquitinated PCNA (Bos taurus)


name: 3-hydroxypropanoate + 2 H(+) + NADH => 3-hydroxypropanal + H2O + NAD(+)


name: ERKs are inactivated by protein phosphatase 2A (Rattus norvegicus)


name: MECP2 binds CREB1 gene promoter (Homo sapiens)


name: PRDM4 inhibits cyclin E transcription (Homo sapiens)


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Rattus norvegicus)


name: hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity


name: (2Z,6Z)-farnesyl diphosphate => (E)-beta-farnesene + diphosphate


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Drosophila melanogaster)


name: 2 H(+) + 2 malonyl-CoA + octanoyl-CoA = 4-hydroxy-6-heptylpyran-2-one + 2 CO2 + 3 CoA


name: Digestion of triacylglycerols by extracellular pancreatic lipase-related protein 2 (Sus scrofa)


name: Parkin transfers Ub to misfolded proteins (Danio rerio)


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Rattus norvegicus)


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Dictyostelium discoideum)


name: a sphingoid 1-phosphate <=> a fatty aldehyde + phosphoethanolamine


name: D-glucosamine 6-phosphate + NADP(+) <=> 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + 2 H(+) + NADPH


name: Expression of IFNG-stimulated genes (Homo sapiens)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Canis familiaris)


name: a quinol + sulfate => a quinone + H2O + sulfite


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Xenopus tropicalis)


name: 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX => coproporphyrinogen III + 2 S-adenosyl-L-methionine


name: Constitutive phosphorylation  by pERK1/2 (Schizosaccharomyces pombe)


name: Translocation of TGN-lysosome vesicle to lysosome (Homo sapiens)


name: SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Schizosaccharomyces pombe)


name: CoA + O-decanoyl-(R)-carnitine => (R)-carnitine + decanoyl-CoA


name: 2 chloride(in) + H(+)(out) = 2 chloride(out) + H(+)(in)


name: ADP(out) + dAMP(in) + H(+)(out) = ADP(in) + dAMP(out) + H(+)(in)


name: [(1->6)-alpha-D-glucosyl](n) + sucrose <=> (1->3)-alpha-D-glucosyl-[(1->6)-alpha-D-glucosyl](n) + D-fructose


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + an N-acylsphing-4-enine 1-phosphoethanolamine


name: ATP + pre-putrebactin = AMP + diphosphate + H(+) + putrebactin


name: 3-amino-4-hydroxybenzoate + H(+) + 2 H2O + phosphate => 2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate


name: NUMB:ITCH bind and ubiquitnate GLI1 (Xenopus tropicalis)


name: H2O + N-formyl-L-methionine => formate + L-methionine


name: RNA-binding transcription regulator activity


name: 2-(9Z-octadecenoyl)-glycerol + eicosanoyl-CoA <=> 1-eicosanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Mus musculus)


name: 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = 5alpha-cholestane-3beta,5,6beta-triol


name: dauca-4,7-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = asperaculane D + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)


name: L-alanine(in) + L-valine(out) => L-alanine(out) + L-valine(in)


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Xenopus tropicalis)


name: Phosphorylation of COP1 at Ser-387  by ATM (Homo sapiens)


name: acetyl-CoA + N(6)-methyl-L-lysyl-[histone] = CoA + H(+) + N(6)-acetyl-N(6)-methyl-L-lysyl-[histone]


name: botF LC cleaves target cell VAMP2 (Homo sapiens)


name: GDIs block activation of RHOC (Gallus gallus)


name: MMP14:TIMP2 binds proMMP2 (Xenopus tropicalis)


name: L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] <=> H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu)


name: Phosphorylation of LAT by p-SYK (Sus scrofa)


name: Degradation of MHC I Complex (Homo sapiens)


name: nucleoside monophosphate kinase activity


name: GABRR pentamers:GABA transports extracellular Cl- to cytosol (Sus scrofa)


name: ADP + H(+) + 4 Na(+)(out) + phosphate => ATP + H2O + 4 Na(+)(in)


name: AP4 transports APP from trans-Golgi network to endosome lumen (Dictyostelium discoideum)


name: Pancreatic proteases degrade TCN1:RCbl (Xenopus tropicalis)


name: (Z)-(4-hydroxyphenyl)acetaldehyde oxime <=> 4-hydroxyphenylacetonitrile + H2O


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Caenorhabditis elegans)


name: an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc6S derivative + GDP-beta-L-fucose => an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc6S derivative + GDP + H(+)


name: a 1-acylglycerol + hexadecanoyl-CoA => an hexadecanoyl-acylglycerol + CoA


name: Endocytosis of cya:lef:(pagA(197-794):ANTXR2 oligomer) (plasma membrane to endosome membrane) (Homo sapiens)


name: H2O + UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose = 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + H(+) + UDP


name: cholestanol + O2 + reduced [NADPH--hemoprotein reductase] = (24S)-hydroxycholestanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: asparagine synthase (glutamine-hydrolyzing) activity


name: CHEK1 phosphorylates BRCA2 (Homo sapiens)


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Xenopus tropicalis)


name: (3S)-3-hydroxyadipyl-CoA <=> (E)-2,3-didehydroadipoyl-CoA + H2O


name: ARSC hydrolyzes steroid sulfates (Canis familiaris)


name: H2O + NAD(+) + retinal => 2 H(+) + NADH + retinoate


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Canis familiaris)


name: 3-oxoadipyl-CoA + H(+) + NADH => (3S)-3-hydroxyadipyl-CoA + NAD(+)


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Homo sapiens)


name: an 8-hydroxyflavone + S-adenosyl-L-methionine <=> an 8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: H2O + L-homoseryl-tRNA(Lys) => H(+) + L-homoserine + tRNA(Lys)


name: acetyl phosphate + L-lysine <=> H(+) + N(6)-acetyl-L-lysine + phosphate


name: mTORC1 binds RHEB:GTP (Canis familiaris)


name: Caspase-mediated cleavage of alpha adducin (Canis familiaris)


name: EBP isomerizes ZYMSTNL to LTHSOL (Dictyostelium discoideum)


name: TFAP2A binds the PAX3 gene (Homo sapiens)


name: (12Z)-10-hydroxyoctadecenoate => (9Z,12Z)-octadecadienoate + H2O


name: Dimerisation of nucleoprotein (Homo sapiens)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Sus scrofa)


name: Recruitment of CstF to the CPSF Bound Pre-mRNA (Bos taurus)


name: carbamoyl phosphate + ornithine => citrulline + orthophosphate (Gallus gallus)


name: acetyl-CoA + deacetylcephalosporin C <=> cephalosporin C + CoA


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose => beta-D-Glc-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: DVL2 is phosphorylated by PKC (Sus scrofa)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Homo sapiens)


name: H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + polytolypin => 2-deoxypolytolypin + O2 + reduced [NADPH--hemoprotein reductase]


name: thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Danio rerio)


name: 2-oxoglutarate + L-aspartate => L-glutamate + oxaloacetate


name: D-galactaro-1,4-lactone = 5-dehydro-4-deoxy-D-glucarate + H(+)


name: 3-dehydro-alpha-D-glucosyl beta-D-fructofuranoside + H2O <=> 3-dehydro-D-glucose + D-fructose


name: H2O + O2 + salicylaldehyde = H(+) + H2O2 + salicylate


name: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH => 5,10-methylenetetrahydromethanopterin + NAD(+)


name: H(+) + H2O + N-(20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] => N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase]


name: RHOA:GTP translocates to the ER membrane (Danio rerio)


name: catechol + NAD(+) + nitrite => NADH + nitrobenzene + O2


name: Corticotropin cleavage from POMC (Sus scrofa)


name: CAPN:4xCa2+:CAPNS cleave cytoskeletal proteins (Canis familiaris)


name: Cleavage of S protein into S1:S2 (Homo sapiens)


name: PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Rattus norvegicus)


name: Cdt1 is displaced from the pre-replicative complex (Caenorhabditis elegans)


name: Association of HMGB1/HMGB2 with chromatin (Xenopus tropicalis)


name: alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP-beta-L-fucose = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc + GDP + H(+)


name: K63polyUb-TRAF6 ubiquitinates TAK1 (Homo sapiens)


name: (2E)-decenoyl-CoA + NADP(+) <=> (2E,4E)-decadienoyl-CoA + H(+) + NADPH


name: ATP + beta-alanine + tryptamine <=> AMP + beta-alanyl-tryptamine + diphosphate + H(+)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphoethanolamine + H(+) + NADPH => 1-hexadecanoyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphoethanolamine + NADP(+)


name: 17alpha-hydroxyprogesterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + progesterone + reduced [NADPH--hemoprotein reductase]


name: Autophosphorylation of insulin receptor (Sus scrofa)


name: a fatty aldehyde + H2O + NAD(+) <=> a fatty acid + 2 H(+) + NADH


name: STAMBPL1 is a deubiquitinase (Canis familiaris)


name: (S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + CO2 + pyruvate + succinate


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine <=> a cardiolipin + ethanolamine


name: 2-glyceryl-prostaglandin H2 => 2-glyceryl-prostaglandin E2


name: (24R,25R)-3alpha,7alpha,24-trihydroxy-5beta-cholestan-26-oyl-CoA + NAD(+) => 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + H(+) + NADH


name: SLC2A9 transports Fru, Glc, urate (Sus scrofa)


name: Expression of GABPA (NRF2 alpha subunit) (Homo sapiens)


name: SDH complex dehydrogenates succinate (Mus musculus)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O <=> (1S,4E,8E,12E)-2,2,5,9,13-pentamethylcyclopentadeca-4,8,12-trien-1-ol + diphosphate


name: p62 binds ubiquitinated mitochondrial substrates (Dictyostelium discoideum)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Canis familiaris)


name: Factor H binds host cell surface markers (Danio rerio)


name: IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Bos taurus)


name: Activated TLR4:TICAM1 recruits TRAF6 (Gallus gallus)


name: MTRR reduces cob(II)alamin to meCbl (Dictyostelium discoideum)


name: (25R)-3beta-hydroxycholest-5-en-7-one-26-al + H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3beta-hydroxycholest-5-en-7-one-26-oate + H2O + 2 oxidized [adrenodoxin]


name: ERK1/2 phosphorylates MSK1 (Canis familiaris)


name: TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin (Homo sapiens)


name: LRPP4(LRPP1-3,5) hydrolyse LPA (Bos taurus)


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Danio rerio)


name: RNR (M1M2B) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Xenopus tropicalis)


name: (3R)-hydroxytetradecanoyl-CoA + NAD(+) = 3-oxotetradecanoyl-CoA + H(+) + NADH


name: FMO3:FAD N-oxidises TMA to TMAO (Caenorhabditis elegans)


name: 3,4-dihydroxybenzoate + 2 H(+) + NADPH => 3,4-dihydroxybenzaldehyde + H2O + NADP(+)


name: FPGS-2 transforms THF to THFPG (Sus scrofa)


name: DCN (decorin) degradation by MMP2, MMP3, MMP7 (Sus scrofa)


name: H(+) + isatin + NADPH = 3-hydroxyindolin-2-one + NADP(+)


name: (R)-carnitine + 4,8-dimethylnonanoyl-CoA => CoA + O-4,8-dimethylnonanoyl-(R)-carnitine


name: cytochrome-b5 reductase activity, acting on NAD(P)H


name: APC/C:Cdh1-mediated degradation of Skp2 (Homo sapiens)


name: FAD + H(+) + heptadecanoyl-CoA <=> FADH2 + trans-2-heptadecenoyl-CoA


name: TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10 (Homo sapiens)


name: isoprenoid diphosphate phosphatase activity


name: hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] => (E)-caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Sus scrofa)


name: 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O = 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde


name: eicosanoyl-CoA + sphing-4-enine => CoA + H(+) + N-eicosanoyl-sphing-4-enine


name: CO2 + dihydroclavaminate + H2O + succinate => 2-oxoglutarate + O2 + proclavaminate


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(38-hydroxyoctatriacontenoyl)-sphing-4-enine <=> a diacylglycerol + an N-(38-(9Z,12Z-octadecadienoyloxy)-octatriacontenoyl)-sphing-4-enine


name: DERA cleaves dR5P to GA3P and CH3CHO (Xenopus tropicalis)


name: L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Danio rerio)


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Canis familiaris)


name: GABAB heterodimeric receptor binds GABA (Dictyostelium discoideum)


name: Formation of DSIF:NELF:early elongation complex (Xenopus tropicalis)


name: Assembly of hexameric IL-6 receptor (Sus scrofa)


name: Type II receptor phosphorylates type I receptor (Sus scrofa)


name: 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO2 + NH4(+) => 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + H(+) + 2 H2O


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Mus musculus)


name: XPO1 binds the beta-catenin:CBY complex (Homo sapiens)


name: HMGB1 binds TLR4:LY96 (Canis familiaris)


name: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose = an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H(+)


name: SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Homo sapiens)


name: NUMB:ITCH bind and ubiquitnate GLI1 (Gallus gallus)


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Rattus norvegicus)


name: Conjugation of SUMO1 to UBA2:SAE1 (Schizosaccharomyces pombe)


name: a ribonucleoside 5'-phosphate + H2O => a ribonucleoside + phosphate


name: Translocation of STAT1 dimer to nucleus (Xenopus tropicalis)


name: Pre-snRNA transcript initiation, Integrator binding, LEC binding (Canis familiaris)


name: MSH2:MSH6 exchanges ADP for ATP (Plasmodium falciparum)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + AH2 + O2 = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + A + 2 H2O


name: ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Gallus gallus)


name: (d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Homo sapiens)


name: NF-kB migrates to the nucleus and turns on transcription (Bos taurus)


name: H2O + phlorizin <=> beta-D-glucose + phloretin


name: Estrogen-responsive CXXC5 gene expresion (Homo sapiens)


name: 4-vinylphenol + O2 <=> 4-hydroxybenzaldehyde + formaldehyde


name: TBC1D25 (OATL1) binds ATG8 homologues (Drosophila melanogaster)


name: 3''-dehydroisoorientin + H2O2 => isoorientin + O2


name: MTA2-NuRD complex deacetylates TP53 (Canis familiaris)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)


name: PLPP1,2,3 dephosphorylate cytosolic sphingosine-1-phosphate (Saccharomyces cerevisiae)


name: 3 (R)-2-hydroxy-3-methylbutyrate + 6 ATP + 3 L-phenylalanine + 3 S-adenosyl-L-methionine => 6 AMP + beauvericin + 6 diphosphate + 6 H(+) + 3 S-adenosyl-L-homocysteine


name: a pyrimidine ribonucleoside + H2O => a pyrimidine nucleobase + D-ribose


name: TBK1 binds K63-pUb-TANK:K63-pUb-TRAF3:TRIF:activated TLR3  (Homo sapiens)


name: ADP + H(+) + Na(+)(out) + phosphate => ATP + H2O + Na(+)(in)


name: PIAS4 SUMOylates VDR with SUMO2 (Xenopus tropicalis)


name: 2 a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol = a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a 1,2-diacyl-sn-glycerol


name: CDC6 association with ORC(1-6) at replication origins (Homo sapiens)


name: (R)-nicotine + A + H2O => (R)-6-hydroxynicotine + AH2


name: Corticotropin cleavage from POMC (Homo sapiens)


name: Opioid receptors bind opioid peptides (Xenopus tropicalis)


name: IL20 binds to IL22RA1:JAK1:IL20RB (Rattus norvegicus)


name: 2 Fe(III)-[cytochrome c] + H2O + sulfite => 2 Fe(II)-[cytochrome c] + 2 H(+) + sulfate


name: (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine = a diacylglycerol + an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine


name: 2-dehydro-3-deoxy-L-fuconate + NAD(+) => 2,4-didehydro-3-deoxy-L-rhamnonate + H(+) + NADH


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + maniladiol + oxidized [NADPH--hemoprotein reductase]


name: 2 catechol + O2 => 2 1,2-benzoquinone + 2 H2O


name: RUNX1:CBFB binds CREBBP (Drosophila melanogaster)


name: Active LTK recruits GRB2:SOS1 (Mus musculus)


name: epoxybetaenone + H2O + NADP(+) => dehydroprobetaenone I + H(+) + NADPH + O2


name: LTK binds ALKAL ligand (Xenopus tropicalis)


name: 22-oxodocosanoate + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 22-hydroxydocosanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Phenol can form a sulfate conjugate (Homo sapiens)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Sus scrofa)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-glucose => a 1,2-diacyl-3-O-[beta-D-glucopyranosyl-(1->6)-beta-D-galactopyranosyl]-sn-glycerol + H(+) + UDP


name: 3-oxochenodeoxycholate + H(+) + NADH => chenodeoxycholate + NAD(+)


name: Trimerization of HSF1 in the nucleus (Homo sapiens)


name: Dimerization of DAP12 (Rattus norvegicus)


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Dictyostelium discoideum)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Canis familiaris)


name: Phosphorylation of L1 by EPHB2 (Homo sapiens)


name: N-hydroxy-L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: Collagen type XIX degradation (Rattus norvegicus)


name: RAB3IP stimulates nucleotide exchange on RAB8A  (Sus scrofa)


name: CO2 + NADH + UDP-beta-L-threo-pentopyranos-4-ulose => NAD(+) + UDP-alpha-D-glucuronate


name: N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity


name: 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine


name: Zinc is an agonist of GPR39 (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 + octadecanoyl-CoA


name: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + UDP-alpha-D-glucuronate = an alpha-D-glucuronosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + H(+) + UDP


name: ATP + L-seryl-[3-methyl-2-oxobutanoate dehydrogenase] <=> ADP + H(+) + O-phospho-L-seryl-[3-methyl-2-oxobutanoate dehydrogenase]


name: 16alpha,17alpha-estriol 3-O-(beta-D-glucuronate) + H(+) + UDP => 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate


name: (R)-lipoyl-GMP + diphosphate => (R)-lipoate + GTP + H(+)


name: C-C motif chemokine 21 receptor activity


name: H2O + UDP-N-acetyl-alpha-D-galactosamine = 2 H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UMP


name: Desaturation of Linoleoyl-CoA to gamma-linolenoyl-CoA (Caenorhabditis elegans)


name: H2O + pentanamide => NH4(+) + pentanoate


name: ferric-chelate reductase (NADH) activity


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Rattus norvegicus)


name: all-trans-4-hydroxyretinol + H2O + 2 oxidized [adrenodoxin] => all-trans-retinol + 2 H(+) + O2 + 2 reduced [adrenodoxin]


name: MeSeO2H is reduced to MeSeOH by TXNRD1 (Plasmodium falciparum)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + di-(9Z)-octadecenoylglycerol


name: HRSP12 deaminates 2AA to 2OBUTA (Rattus norvegicus)


name: (6S)-NADHX + ATP => ADP + H(+) + NADH + phosphate


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Plasmodium falciparum)


name: orcinol + S-adenosyl-L-methionine => 3-methoxy-5-methylphenol + H(+) + S-adenosyl-L-homocysteine


name: 1(F)-beta-D-fructosylsucrose + sucrose => 1,6-kestotetraose + beta-D-glucose


name: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) => 3,4-dihydroxybenzoate + CO2 + NADH


name: O-acetyl-L-serine + thiosulfate = acetate + H(+) + S-sulfo-L-cysteine


name: SPNS2,MFSD2B transport S1P from cytosol to extracellular region (Rattus norvegicus)


name: Release of p-STAT2:p-STAT1 dimer (Rattus norvegicus)


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Mus musculus)


name: Phosphorylation of CBL (EGFR:CBL) (Gallus gallus)


name: 3,5-dibromo-4-hydroxybenzoate + NH4(+) => 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O


name: 4-thiouridine + ATP = 4-thiouridine 5'-phosphate + ADP + H(+)


name: (5R,6S)-5,6-epoxi-beta-cryptoxanthin + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => beta-cryptoxanthin + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin]


name: Surface deployment of platelet dense granule membrane components (Bos taurus)


name: 3'-O-methyltricetin + S-adenosyl-L-methionine = 3',5'-di-O-methyltricetin + H(+) + S-adenosyl-L-homocysteine


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene + A <=> 1,1'-dihydroxy-3,4-didehydro-1,2-dihydrolycopene + AH2


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Xenopus tropicalis)


name: 1-acyl LPC is acylated to PC by LPCAT (Dictyostelium discoideum)


name: MITF-M-dependent TYR gene expression (Homo sapiens)


name: 4 Fe(III)-[cytochrome c] + L-galactono-1,4-lactone <=> 4 Fe(II)-[cytochrome c] + 5 H(+) + L-dehydroascorbate


name: G-protein alpha subunit is inactivated (Schizosaccharomyces pombe)


name: 3-oxosphinganine + dodecanoyl-CoA => CoA + H(+) + N-dodecanoyl-3-oxosphinganine


name: (2Z,6E)-farnesyl diphosphate + 9 isopentenyl diphosphate => di-trans,nona-cis-dodecaprenyl diphosphate + 9 diphosphate


name: 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + macrocyclic archaeol => AH2 + archaeol + 2 S-adenosyl-L-methionine


name: Proteasome proteolyzes ub-HIF-alpha (Caenorhabditis elegans)


name: 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Mus musculus)


name: LYPLA2 hydrolyses PALM-C3,4-GAP43 (Bos taurus)


name: H2O + N(2)-(4-aminobutanoyl)-L-lysine = 4-aminobutanoate + L-lysine


name: a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol + an N-(34-hydroxytetratriacontadienoyl)-sphing-4-enine => a diacylglycerol + an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontadienoyl)-sphing-4-enine


name: CBL ubiquitinates FRS2 and FGFR2 (Bos taurus)


name: RNLS:FAD oxidises dh-beta-NAD to NAD+ (Mus musculus)


name: SCNN channels transport extracellular Na+ to cytosol (Gallus gallus)


name: UDP-alpha-D-galactose(in) + UMP(out) => UDP-alpha-D-galactose(out) + UMP(in)


name: ATP + cholate(in) + H2O <=> ADP + cholate(out) + H(+) + phosphate


name: CDC42:GTP:FMNL2 binds Profilin:G-actin (Sus scrofa)


name: Mature S-Farn-Me KRAS4B translocates to plasma membrane (Canis familiaris)


name: ATP + CoA + docosanoate <=> AMP + diphosphate + docosanoyl-CoA


name: RhCG mediates ammonium influx into kidney collecting duct cells (Homo sapiens)


name: SMURF1 binds phosphorylated PARD6A (Rattus norvegicus)


name: guaiacol + S-adenosyl-L-methionine <=> H(+) + S-adenosyl-L-homocysteine + veratrole


name: NUDT13 hydrolyses AP6A to AP4 and ADP (Sus scrofa)


name: MAP1LC3B binds KEAP1 and SQSTM1 (Bos taurus)


name: Rnd1 interacts with Plexin-B1:Sema4D (Gallus gallus)


name: Formation of the preholoproteasome (Caenorhabditis elegans)


name: p-PKR dimer phosphorylates TP53 tetramer (Mus musculus)


name: Activation of RAC1 by VAV (Xenopus tropicalis)


name: H2O + N-acetyl-D-glucosamine + O2 = H(+) + H2O2 + N-acetyl-D-glucosaminate


name: bPIX exchanges GTP for GDP on RAC, activating it (Caenorhabditis elegans)


name: 1(F)-alpha-D-galactosylraffinose + sucrose => 2 raffinose


name: PNPLA4 hydrolyzes retinyl palmitate (Xenopus tropicalis)


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Mus musculus)


name: TECR,TECRL dehydrogenate TOD-CoA to ST-CoA (Canis familiaris)


name: SFTPAs translocate from ER membrane to extracellular region (Bos taurus)


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Bos taurus)


name: (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 = (E)-2,4-dihydroxycinnamoyl-CoA + CO2 + succinate


name: 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]


name: H2O + hexanoyl-CoA = adenosine 3',5'-bisphosphate + 2 H(+) + hexanoyl-4'-phosphopantetheine


name: CYGB:O2 dissociates (Xenopus tropicalis)


name: griseophenone D + S-adenosyl-L-methionine => griseophenone C + S-adenosyl-L-homocysteine


name: Translocation Of Telomerase RNP And Alignment Of RNA Template (TERC) To Extended Single Stranded Telomeric Chromosome-End (Gallus gallus)


name: ATP + H2O + leukotriene B4(in) <=> ADP + H(+) + leukotriene B4(out) + phosphate


name: hydrogencarbonate(out) + iodide(in) = hydrogencarbonate(in) + iodide(out)


name: (S)-2-hydroxyglutarate(out) + 3 Na(+)(out) => (S)-2-hydroxyglutarate(in) + 3 Na(+)(in)


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Homo sapiens)


name: 3beta-hydroxy-5-androstene-7,17-dione + H(+) + NADPH => 3beta,7alpha-dihydroxyandrost-5-en-17-one + NADP(+)


name: p-S167-ESR1 translocates from the cytosol to the nucleus (Xenopus tropicalis)


name: 3-amino-2,3-dideoxy-scyllo-inosose + L-glutamine <=> 2-deoxystreptamine + 2-oxoglutaramate


name: REST binds the VGF promoter (Homo sapiens)


name: cAMP induces dissociation of inactive PKA tetramers (Caenorhabditis elegans)


name: 17beta-estradiol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 17beta-estradiol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate


name: 5,6-dihydrouridine(20) in tRNA + NAD(+) <=> H(+) + NADH + uridine(20) in tRNA


name: (2S)-naringenin 7-O-beta-D-glucoside + malonyl-CoA <=> (2S)-naringenin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: pyruvate transmembrane transporter activity


name: MPC1:MPC2 imports PYR, H+ to mitochondrial matrix (Homo sapiens)


name: Phosphorylated GAB1 recruits PI3K to MET (Canis familiaris)


name: TRAIL:TRAIL-Receptor2 Trimer:FADD complex binds procaspase-10 (Gallus gallus)


name: peroxisome matrix targeting signal-2 binding


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Xenopus tropicalis)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Drosophila melanogaster)


name: Fusion of early-endosome derived vesicles at the TGN (Gallus gallus)


name: PIAS1 SUMOylates SP3 with SUMO2 (Mus musculus)


name: phosphatidylinositol trisphosphate phosphatase activity


name: L-arginyl-[protein] + NADP(+) => H(+) + N(omega)-(2'-phospho-ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide


name: (3S)-hydroxydocosanoyl-CoA + NAD(+) => 3-oxodocosanoyl-CoA + H(+) + NADH


name: Initial activation of proMMP7 by trypsin (Danio rerio)


name: all-trans-nonaprenyl diphosphate + 6 diphosphate => (2E,6E)-farnesyl diphosphate + 6 isopentenyl diphosphate


name: IL21 receptor JAK phosphorylation (Bos taurus)


name: 2,5-dioxopentanoate + H2O + NADP(+) => 2-oxoglutarate + 2 H(+) + NADPH


name: Growth hormone binds the growth hormone receptor (Danio rerio)


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Mus musculus)


name: CYP3A7 can 6beta-hydroxylate testosterone (Sus scrofa)


name: RGGT binds the RAB-binding subunit (Homo sapiens)


name: RAB33B:GTP binds RIC1:RGP1 (Canis familiaris)


name: NADH dehydrogenase (ubiquinone) activity


name: Prolactin receptor ligands bind the prolactin receptor (Sus scrofa)


name: apo-UQCRFS1 binds LYRM7 (Drosophila melanogaster)


name: ALPK1:ADP-heptose:p-T9-TIFA oligomer:K63pUb-TRAF6 oligomer recruits MAP3K7 (TAK1) (Gallus gallus)


name: abacavir [extracellular] => abacavir [cytosol] (Mus musculus)


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Sus scrofa)


name: ALOX5 oxidises EPA to 5-HEPE (Rattus norvegicus)


name: (6E)-8-methylnon-6-enoyl-CoA + vanillylamine = capsaicin + CoA + H(+)


name: FADH2 + N-methylnicotinate + O2 => (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FAD + H(+)


name: H(+) + hispidin + NADH + O2 => 3-hydroxyhispidin + H2O + NAD(+)


name: an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O <=> an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + D-galactosamine


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Caenorhabditis elegans)


name: PI3K associates with phosphorylated GAB2 (Bos taurus)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Rattus norvegicus)


name: 8,12-diethyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine => 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + H(+) + S-adenosyl-L-homocysteine


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Xenopus tropicalis)


name: ACBD6 binds LCFA-CoA (Drosophila melanogaster)


name: RUNX3 translocates to the nucleus (Caenorhabditis elegans)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)


name: STAT3 is phosphorylated downstream of active ALK (Homo sapiens)


name: L-ornithine + pyruvate = 5-amino-2-oxopentanoate + L-alanine


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + L-glutamate


name: Interaction of SIGLEC14/15/16 and DAP12 (Canis familiaris)


name: docosanoate + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 2-hydroxydocosanoate + 2 Fe(III)-[cytochrome b5] + H2O


name: (2S)-2-hydroxy-3-phenylpropanenitrile => 2-phenylacetaldehyde + hydrogen cyanide


name: peptide transmembrane transporter activity


name: Glutathione is taken up by the bacterium (Homo sapiens)


name: chloride + S-adenosyl-L-methionine => 5'-chloro-5'-deoxyadenosine + L-methionine


name: uridine(746) in 23S rRNA = pseudouridine(746) in 23S rRNA


name: S-methyl-5-thio-alpha-D-ribose 1-phosphate => S-methyl-5-thio-D-ribulose 1-phosphate


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Xenopus tropicalis)


name: fumarate(out) + 2 H(+)(out) => fumarate(in) + 2 H(+)(in)


name: estrone 3-sulfate(out) + n H(+)(out) <=> estrone 3-sulfate(in) + n H(+)(in)


name: H2O + NAD(+) + nitrous oxide = H(+) + NADH + 2 nitric oxide


name: H2O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) <=> 2 H(+) + N-succinyl-L-glutamate + NADH


name: (2S)-naringenin + O2 + reduced [NADPH--hemoprotein reductase] => 2-hydroxy-2,3-dihydrogenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Interleukin-2 receptor alpha binds interleukin-2 (Rattus norvegicus)


name: (E)-caffeate + ATP + H(+) + 2 malonyl-CoA = AMP + 2 CO2 + 2 CoA + diphosphate + hispidin


name: Defective MyD88 does not oligomerize within the complex of activated TLR5 (Homo sapiens)


name: cytidine(8) in tRNA + H(+) + H2O = NH4(+) + uridine(8) in tRNA


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Canis familiaris)


name: 2 2-acetylphloroglucinol = 1,3,5-trihydroxybenzene + 2,4-diacetylphloroglucinol + H(+)


name: a menaquinone + H2O + nitrite => a menaquinol + nitrate


name: H(+)(out) + L-aspartate(in) + L-glutamate(out) => H(+)(in) + L-aspartate(out) + L-glutamate(in)


name: D-maltoheptaose + O2 = D-maltoheptaono-1,5-lactone + H2O2


name: SLC46A1 transports FOLA from extracellular region to cytosol (Drosophila melanogaster)


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Bos taurus)


name: Hydrolysis of choloyl-CoA to cholate and CoASH (Mus musculus)


name: Detachment of WASP/WAVE (Drosophila melanogaster)


name: SUMOylation of XPC with SUMO1 (Saccharomyces cerevisiae)


name: (3S)-hydroxy-(5Z-tetradecenoyl)-CoA + NAD(+) <=> 3-oxo-(5Z-tetradecenoyl)-CoA + H(+) + NADH


name: Activated FGFR2 phosphorylates PPTN11 (Danio rerio)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Plasmodium falciparum)


name: 2-methylpropanenitrile + O2 + reduced [NADPH--hemoprotein reductase] = 2-hydroxy-2-methylpropanenitrile + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: butanoate + NAD(+) => (2E)-2-butenoate + H(+) + NADH


name: AH2 + S-methyl-1-thio-D-xylulose 5-phosphate <=> 1-deoxy-D-xylulose 5-phosphate + A + methanethiol


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Canis familiaris)


name: Activation of PAKs by RAC1 and CDC42 (Sus scrofa)


name: Caspase-mediated cleavage of vimentin at TNLD (429) (Xenopus tropicalis)


name: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine = 3',5-dihydroxy-3,4',7-trimethoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: 2-methoxy-6-all-trans-decaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = 6-methoxy-3-methyl-2-all-trans-decaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: Active PLCG1 dissociates from TrkA receptor (Homo sapiens)


name: 3 [thioredoxin]-dithiol + arsenic triglutathione + 3 S-adenosyl-L-methionine = 3 [thioredoxin]-disulfide + 3 glutathione + 3 H(+) + 3 S-adenosyl-L-homocysteine + trimethylarsine


name: AKR1A1 reduces D-glucuronate to L-gulonate (Danio rerio)


name: L mRNA is translated into protein L (Homo sapiens)


name: formyl-CoA + succinate = formate + succinyl-CoA


name: RXRA:PPARD binds FABP5:atRA (Canis familiaris)


name: H2O + P(1),P(5)-bis(5'-adenosyl) pentaphosphate => adenosine 5'-tetraphosphate + AMP + 2 H(+)


name: benzyl alcohol + CO2 + L-leucine => H(+) + H2O + N-benzyloxycarbonyl-L-leucine


name: Arachidonate is oxidised to 12R-HpETE by ALOX12B (Xenopus tropicalis)


name: IKBKG subunit of IKK complex binds K63pUb- RIP1 within the TLR3 complex (Homo sapiens)


name: 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oyl-CoA + AMP + diphosphate => 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oate + ATP + CoA


name: IMPDH tetramers dehydrogenate 6TIMP to 6TXMP (Caenorhabditis elegans)


name: N-acetyl-L-aspartate(in) + 3 Na(+)(in) => N-acetyl-L-aspartate(out) + 3 Na(+)(out)


name: SLC22A18 exchanges extracellular organic cations for cytosolic H+ (Canis familiaris)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Schizosaccharomyces pombe)


name: C35-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+) => 2 (S)-methylmalonyl-CoA + 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH


name: HNF1A-dependent synthesis of HNF4G protein (Homo sapiens)


name: p-SHC1 binds integrin alpha5beta1:fibronectin (Canis familiaris)


name: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate => 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O


name: riboflavin transmembrane transporter activity


name: GAR + 10-Formyl-THF => FGAR + THF (Homo sapiens)


name: androsterone + NADP(+) = 5alpha-androstan-3,17-dione + H(+) + NADPH


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + trichodiene


name: 4-O-demethylbarbatate + 6 CO2 + 8 CoA + H2O + 2 S-adenosyl-L-homocysteine => 2 acetyl-CoA + 3 H(+) + 6 malonyl-CoA + 2 S-adenosyl-L-methionine


name: CoA + NAD(+) + sulfoacetaldehyde = H(+) + NADH + sulfoacetyl-CoA


name: 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + quiannulatate => 3 O2 + quiannulatene + 3 reduced [NADPH--hemoprotein reductase]


name: ESD dimer hydrolyses S-FGSH to GSH (Rattus norvegicus)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Homo sapiens)


name: Autocleavage of ESPL1 (Separase) (Saccharomyces cerevisiae)


name: H2O + L-asparagine <=> L-aspartate + NH4(+)


name: PTPN6 dephosphorylates JAK3 (Sus scrofa)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Rattus norvegicus)


name: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> 2-methyl-cis-aconitate + H2O


name: (R)-5-methyl-tetronate + o-quinone methide => peniphenone D


name: (1R)-(1-hydroxyethyl)phosphonate + O2 => acetate + 2 H(+) + phosphate


name: p75NTR interacts with RIP2 (Homo sapiens)


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Caenorhabditis elegans)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + H2O <=> a fatty acid + H(+) + sn-glycero-3-phospho-L-serine


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Mus musculus)


name: DHNTP is dephosphorylated by PTPS to PTHP (Homo sapiens)


name: H(+) + maleate + pyruvate => 3-maleylpyruvate + H2O


name: (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) <=> 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: Formation of the PCAF-ATAC complex (Mus musculus)


name: cAMP activates EPAC1 (Schizosaccharomyces pombe)


name: PP2A dephosphorylates serine-127 of YAP1 (Gallus gallus)


name: Activated FGFR4 phosphorylates SHC1 (Bos taurus)


name: AH2 + alpha-D-ribose 1-methylphosphonate 5-phosphate + S-adenosyl-L-methionine = 5'-deoxyadenosine + A + alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H(+) + L-methionine + methane


name: "alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase"


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Caenorhabditis elegans)


name: Two NPFF receptors can bind neuropeptide FF (Bos taurus)


name: PCho is dephosphorylated to Cho by PHOSPHO1 (Drosophila melanogaster)


name: (5-hydroxyindol-3-yl)acetate + 2 H(+) + NADH => (5-hydroxyindol-3-yl)acetaldehyde + H2O + NAD(+)


name: AMP + 2 H(+) + reduced beta-nicotinamide D-ribonucleotide => H2O + NADH


name: Adenylate cyclase increases the GTPase activity of G alpha-olf (Caenorhabditis elegans)


name: 5,6,7,8-tetrahydromethanopterin + NAD(+) = 7,8-dihydromethanopterin + H(+) + NADH


name: [Rab1 protein]-O-phosphocholine-L-serine + H2O => [Rab1 protein]-L-serine + H(+) + phosphocholine


name: adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine


name: Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) (Bos taurus)


name: a penicillin + H2O <=> 6-aminopenicillanate + a carboxylate


name: FOXA1 and GATA3 bind to CCND1 promoter (Sus scrofa)


name: 3'-phosphoadenylyl sulfate + a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol => 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+)


name: GABA loaded synaptic vesicle Docking and Priming (Rattus norvegicus)


name: LPIN catalyzes conversion of phosphatidic acid to diacylglycerol (Canis familiaris)


name: AKT can phosphorylate NR4A1 (NUR77) (Gallus gallus)


name: TBK1 is phosphorylated within the activated TLR4 complex (Mus musculus)


name: PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170) (Mus musculus)


name: 3-oxoadipyl-CoA + succinate => 3-oxoadipate + succinyl-CoA


name: (2E,6E,10E)-geranylgeraniol + ATP => (2E,6E,10E)-geranylgeranyl phosphate + ADP + H(+)


name: 4-chlorophenylacetate + NADH + O2 <=> 3,4-dihydroxyphenylacetate + chloride + NAD(+)


name: (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA + NAD(+) => 3,22-dioxochol-4-en-24-oyl-CoA + H(+) + NADH


name: Association of procollagen type XII (Mus musculus)


name: beta-nicotinamide D-ribonucleotide + H2O <=> D-ribose 5-phosphate + H(+) + nicotinamide


name: Association of profilin with monomeric actin (Rattus norvegicus)


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Gallus gallus)


name: acetate + an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol => a 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H2O


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Plasmodium falciparum)


name: enterobactin(in) + H(+)(out) => enterobactin(out) + H(+)(in)


name: Hypochlorous acid (HOCL) reacts with Lys-monochloramine (Homo sapiens)


name: WWTR1 binds SMAD2/3:SMAD4 heterotrimer (Caenorhabditis elegans)


name: GMP(out) + NAD(+)(in) => GMP(in) + NAD(+)(out)


name: 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one (Saccharomyces cerevisiae)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Canis familiaris)


name: 2-oxobutanoate + L-phenylalanine = (2S)-2-aminobutanoate + 3-phenylpyruvate


name: Superoxide reduces cytochrome c (Dictyostelium discoideum)


name: SIRT4 transfers ADPRib to GLUD (Gallus gallus)


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Sus scrofa)


name: (Z)-(indol-3-yl)-N-(sulfonatooxy)methanimidothioate => (indol-3-yl)acetonitrile + sulfate + sulfur


name: PCSK9:LDLR bind to Clathrin (Sus scrofa)


name: SRC-1 phosphorylates p-Y397-PTK2 (Sus scrofa)


name: PTGIR binds PTGIR agonists (Canis familiaris)


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Mus musculus)


name: ATP + CoA + octanoate = AMP + diphosphate + octanoyl-CoA


name: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O => 2 beta-L-arabinofuranose


name: ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate


name: 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Rattus norvegicus)


name: carbovir monophosphate + ATP => carbovir diphosphate + ADP (Homo sapiens)


name: CO2 + 2 CoA + cyclo-acetoacetyl-L-tryptophan + H2O => acetyl-CoA + L-tryptophan + malonyl-CoA


name: SDHA:SDHB binds to SDHC:SDHD (Bos taurus)


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Bos taurus)


name: H(+) + H2O + pheophorbide a <=> CO2 + methanol + pyropheophorbide a


name: Association of ADAM and B4GALT1 With ZP3 (Xenopus tropicalis)


name: EHMT1:EHMT2 methylates IL8 promoter (Homo sapiens)


name: a 5'-end dephospho-2'-deoxyribonucleoside-DNA + ATP => a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + ADP + H(+)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Schizosaccharomyces pombe)


name: a 1-acyl-sn-glycero-3-phosphocholine + a cardiolipin => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: NACT co-transports trivalent citrate and a sodium ion (Mus musculus)


name: Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases (Bos taurus)


name: AKT1 phosphorylates NOTCH4 (Gallus gallus)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Rattus norvegicus)


name: ent-kaur-16-ene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] <=> ent-kaur-16-en-19-oate + 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase]


name: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine


name: G-beta:G-gamma inhibits Adenylate cyclase (Mus musculus)


name: CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus (Plasmodium falciparum)


name: MET phosphorylates CBL (Rattus norvegicus)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Caenorhabditis elegans)


name: 2 ATP + H2O + hydrogencarbonate + L-glutamine => 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate


name: (+)-artemisinic aldehyde + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (+)-artemisinic alcohol + O2 + reduced [NADPH--hemoprotein reductase]


name: H2O + N(6)-acetyl-L-lysyl-[alpha-tubulin] <=> acetate + L-lysyl-[alpha-tubulin]


name: linalool + O2 + reduced [NADPH--hemoprotein reductase] = (6E)-8-hydroxylinalool + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)


name: RB1 translocates to the nucleus (Xenopus tropicalis)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Caenorhabditis elegans)


name: SLCO1B1 transports T3,T4 from extracellular region to cytosol (Mus musculus)


name: 2-oxoglutarate + H2O2 + NH4(+) => H2O + L-glutamate + O2


name: Receptor CCR10 binds CCL27 and 28 ligands (Canis familiaris)


name: AP1G2 binds HGS and CHMP2A (Mus musculus)


name: Interleukin-12 binds Interleukin-12 receptor (Sus scrofa)


name: 2-deoxy-scyllo-inosamine + 2-oxoglutaramate => 2-deoxy-L-scyllo-inosose + L-glutamine


name: 3-hydroxy-6-carboxyhexanoyl-CoA + H(+) => 6-oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O


name: Hydroxyl-initiated lipid peroxidation (Homo sapiens)


name: (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H(+) => (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O


name: H2O + trithionate => H(+) + sulfate + thiosulfate


name: Active NIK phosphorylates IKKA dimer (Canis familiaris)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + dodecanoyl-[ACP] <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(dodecanoyl)-lipid IVA (E. coli) + holo-[ACP]


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Drosophila melanogaster)


name: hexadecanoyl-CoA + sphinga-(4E,8Z)-dienine = CoA + H(+) + N-hexadecanoylsphinga-(4E,8Z)-dienine


name: FA anion flip-flops to the opposite surface (Danio rerio)


name: (1S)-1,25-dihydroxy-24-oxocalciol + 2 H(+) + O2 + 2 reduced [adrenodoxin] = (1S)-1,23,25-trihydroxy-24-oxocalciol + H2O + 2 oxidized [adrenodoxin]


name: DHAP is converted to G3P by GPD1/GPD1L (Caenorhabditis elegans)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer on the G strand of the telomere (Canis familiaris)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Homo sapiens)


name: Decitabine triphosphate incorporates into DNA (Homo sapiens)


name: Transcriptional activation of Citrate lyase monomer gene by ChREBP:MLX (Homo sapiens)


name: N(delta)-hydroxy-N(omega)-methyl-L-arginine + NADH + O2 => H2O + N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + NAD(+)


name: MKRN1 polyubiquitinates PTEN (Sus scrofa)


name: DENND4s exchange GTP for GDP on RAB10 (Xenopus tropicalis)


name: D-gluconate + NADP(+) = 2-dehydro-D-gluconate + H(+) + NADPH


name: 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA => (9Z)-octadecenoyl-CoA + 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O <=> 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine


name: Chico is phosphorylated (Drosophila melanogaster)


name: 2-oxoglutarate + N(6)-acetyl-L-lysine = 6-acetamido-2-oxohexanoate + L-glutamate


name: GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Plasmodium falciparum)


name: NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity


name: [protein]-C-terminal glycine + NAD(+) = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide


name: RCVRN:Ca2+ binds to and inhibits GRK1 (Homo sapiens)


name: PTK2 binds activated MET (Gallus gallus)


name: 3-hydroxyphenylacetate + H(+) + NADH + O2 = H2O + homogentisate + NAD(+)


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Sus scrofa)


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Rattus norvegicus)


name: D-histidine(out) + H(+)(out) + L-ornithine(in) => D-histidine(in) + H(+)(in) + L-ornithine(out)


name: Activated FGFR4 binds PLCG1 (Bos taurus)


name: Activation of RAS by p-KIT bound SOS1 (Canis familiaris)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Plasmodium falciparum)


name: NADSYN1 hexamer amidates NAAD to NAD+ (Saccharomyces cerevisiae)


name: (3R,6R)-1,3,4,6-tetrachlorocyclohexa-1,4-diene + 2 H2O => 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + 2 chloride + 2 H(+)


name: Lysosomal degradation of gap junction plaques (Drosophila melanogaster)


name: (2S)-2-nitrosobutanedioate + H(+) + NADPH + O2 <=> 2-nitrobutanedioate + H2O + NADP(+)


name: 5-amino-6-(D-ribitylamino)uracil + phosphate => 5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O


name: a 3'-end 3'-phosphouridine-RNA + H(+) => a 3'-end 2',3'-cyclophospho-uridine-RNA + H2O


name: [amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O = [amino-group carrier protein]-C-terminal-L-glutamate + L-lysine


name: "[amino group carrier protein]-lysine hydrolase"


name: deacetoxyvindoline + H(+) + S-adenosyl-L-homocysteine => (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine


name: LMCD1 binds GATA6, sequestering it (Rattus norvegicus)


name: 5-methyl-5,6,7,8-tetrahydromethanopterin + H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) <=> 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)


name: SMAD7 binds to SMURF2 (Canis familiaris)


name: p-PKR dimer phosphorylates DHX9 (Xenopus tropicalis)


name: CALCR binds gepants (Xenopus tropicalis)


name: USP48 cleaves polyubiquitin (Mus musculus)


name: Cytosolic folate export across the plasma membrane (Danio rerio)


name: O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2 => (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Mus musculus)


name: THBS1 (Thrombospondin-1) binds Integrin alpha3beta1, alpha4beta1 (Gallus gallus)


name: 2 A + glycine => 2 AH2 + CO2 + hydrogen cyanide


name: Formation of ERCC1:XPF heterodimeric complex (Schizosaccharomyces pombe)


name: GMPPB converts Mannose-1-phosphate to GDP-Mannose (Caenorhabditis elegans)


name: RIP3 binds TRIF to mediate necroptosis (Bos taurus)


name: HLCS biotinylates ACACB (Drosophila melanogaster)


name: acetyl-CoA + GDP-alpha-D-perosamine = CoA + GDP-N-acetyl-alpha-D-perosamine + H(+)


name: 8-carboxy-8-demethylriboflavin 5'-phosphate + 2 A + H2O + L-glutamate = 2-oxoglutarate + 8-amino-8-demethylriboflavin 5'-phosphate + 2 AH2 + CO2


name: (+)-valencene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (+)-nootkatone + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + H(+) => H2O + sepiapterin


name: H(+) + hexan-3-one + NADPH + O2 => ethyl butanoate + H2O + NADP(+)


name: NADPH + 2 oxidized [2Fe-2S]-[protein] <=> H(+) + NADP(+) + 2 reduced [2Fe-2S]-[protein]


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Dictyostelium discoideum)


name: P2X7 mediates membrane pores that include pannexin-1 (Gallus gallus)


name: H2O + phosphoethanolamine <=> acetaldehyde + NH4(+) + phosphate


name: ADP + H(+) + xylitol 5-phosphate => ATP + xylitol


name: naphthalene-1,2,4,8-tetrol => H2O + juglone


name: PIAS4 SUMOylates TP53BP1 with SUMO1 (Schizosaccharomyces pombe)


name: calycosin + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + pseudobaptigenin


name: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine


name: ALDH3B1 oxidises HXAL to PALM (Dictyostelium discoideum)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Dictyostelium discoideum)


name: PARPs transfer ADP-D-ribose to proteins (poly(ADP-ribosyl)ation) (Canis familiaris)


name: Phosphorylation and activation of Ezrin (Bos taurus)


name: UDP-alpha-D-galactose(out) + UMP(in) => UDP-alpha-D-galactose(in) + UMP(out)


name: Nck binds to the active PDGF receptor (Bos taurus)


name: TORC2 (mTOR) phosphorylates AKT at S473 (Schizosaccharomyces pombe)


name: POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 (Homo sapiens)


name: 2 H(+) + monuron + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> 3-(4-chlorophenyl)-1-methylurea + formaldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Sus scrofa)


name: CDK1 phosphorylates RUNX2 (Mus musculus)


name: Cypridina luciferin + O2 <=> CO2 + hnu + oxidized Cypridina luciferin


name: Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Bos taurus)


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Mus musculus)


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Rattus norvegicus)


name: PIAS1,2-1 SUMOylates XRCC4 with SUMO1 (Mus musculus)


name: USP21 deubiquitinates RIPK1,DDX58 (Drosophila melanogaster)


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Dictyostelium discoideum)


name: an N-acylsphing-4-enine + UDP-alpha-D-galactose <=> a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + H(+) + UDP


name: PtpA dephosphorylates GSK3A (Homo sapiens)


name: MASTL phosphorylates ENSA (Homo sapiens)


name: acetyl-CoA + N-acetylneuraminate => CoA + N-acetyl-7-O-acetylneuraminate


name: RNF125 mediated ubiquitination of DDX58, IFIH1 and MAVS (Homo sapiens)


name: a quinol + nitrate => a quinone + H2O + nitrite


name: 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2


name: CYP17A1 cleaves 17aHPREG to DHA (Sus scrofa)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Sus scrofa)


name: CoA + glyoxylate + NADP(+) => H(+) + NADPH + oxalyl-CoA


name: ADP + glutathione(out) + H(+) + phosphate + tauroursodeoxycholate(out) => ATP + glutathione(in) + H2O + tauroursodeoxycholate(in)


name: H(+)(in) + L-lyxopyranose(in) <=> H(+)(out) + L-lyxopyranose(out)


name: ascocorynin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => O2 + polyporic acid + reduced [NADPH--hemoprotein reductase]


name: SUMOylation of RARA with SUMO2 (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate + H2O => (3R,6E)-nerolidol + diphosphate


name: 1-O-dodecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O => 1-O-dodecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 1-O-methyl-8-hydroperoxy-20-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: ATP + formate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = ADP + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate


name: atropine + H2O <=> H(+) + tropate + tropine


name: a ubiquinone + keto-D-fructose = 5-dehydro-D-fructose + a ubiquinol


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycerol + H(+)


name: 2 H(+) + H2O + N-hydroxy-L-tryptophan + oxidized [NADPH--hemoprotein reductase] => L-tryptophan + O2 + reduced [NADPH--hemoprotein reductase]


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol (Sus scrofa)


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + L-lysyl(9)-[histone H3] + 2 succinate


name: 9alpha-copalyl diphosphate => diphosphate + syn-isopimara-7,15-diene


name: T2Rs bind bitter-tasting compounds (Xenopus tropicalis)


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Mus musculus)


name: 2,7-dihydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine <=> 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + H(+) + S-adenosyl-L-homocysteine


name: (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O = (3R)-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA


name: carbamoyl phosphate + L-ornithine <=> H(+) + L-citrulline + phosphate


name: Multiphospho-CERT1-2 binds PPM1L, VAPA/B (Danio rerio)


name: 1-eicosanoylglycerol + H2O = eicosanoate + glycerol + H(+)


name: glycocholate + NAD(+) => 7-oxo-glycodeoxycholate + H(+) + NADH


name: Inhibition of integrin activation by sequestering PIP5KIgamma (Caenorhabditis elegans)


name: DCAKD phosphorylates DP-CoA (Bos taurus)


name: RNF41 ubiquitinates ERBB3 (Gallus gallus)


name: A + H2O + quinaldate <=> AH2 + kynurenate


name: (8S)-8-amino-7-oxononanoate + L-lysine <=> (7R,8S)-7,8-diammoniononanoate + (S)-2-amino-6-oxohexanoate


name: XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Caenorhabditis elegans)


name: Monoiodinated tyrosine can be deiodinated (Rattus norvegicus)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Drosophila melanogaster)


name: Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Sus scrofa)


name: JMJD6 demethylates MeR3-histone H3 (Rattus norvegicus)


name: fumagillol + NADP(+) <=> 5-dehydrofumagillol + H(+) + NADPH


name: malonyl-CoA is decarboxylated to acetyl-CoA in peroxisome (Sus scrofa)


name: (E)-3-diazocoumarate + NADH = (E)-4-coumarate + N2 + NAD(+)


name: Activated FGFR2 phosphorylates FRS2 (Drosophila melanogaster)


name: chloride(in) + glycine(in) + 3 Na(+)(in) => chloride(out) + glycine(out) + 3 Na(+)(out)


name: N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Bos taurus)


name: Plasma membrane FGFR1 fusions autophosphorylate (Homo sapiens)


name: Fluid-phase proteolytic cleavage of factor B (Gallus gallus)


name: Nucleoprotein is ADP-ribosylated (Homo sapiens)


name: Recruitment and activation of Chk1 (Rattus norvegicus)


name: 1-deoxysphinganine + NADP(+) => 1-deoxy-3-dehydrosphinganine + H(+) + NADPH


name: DVL2 is phosphorylated by PKC (Bos taurus)


name: Ubiquitinated DVL is degraded by the proteasome (Danio rerio)


name: beta-amyrin + O2 + reduced [NADPH--hemoprotein reductase] = 16alpha-hydroxy-beta-amyrin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: Translocation of CaN:CaM:NFAT to nucleus (Schizosaccharomyces pombe)


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Sus scrofa)


name: (4-hydroxyphenyl)acetaldehyde + 2 H(+) + NH4(+) + 2 reduced [azurin] => H2O + 2 oxidized [azurin] + tyramine


name: 9-cis-10'-apo-beta-carotenal + beta-ionone => 9-cis-beta-carotene + O2


name: 2 a (3R)-3-isocyanyl-fatty acyl-[ACP] + ATP + L-lysine + 2 NADPH => AMP + an isonitrile lipopeptide + diphosphate + 2 holo-[ACP] + 2 NADP(+)


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Rattus norvegicus)


name: (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) <=> (4Z)-2-oxohept-4-enedioate + CO2


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Schizosaccharomyces pombe)


name: D-fructuronate(in) + H(+)(in) <=> D-fructuronate(out) + H(+)(out)


name: 2,6,9-trimethyl-13-oxatetracyclo[6.3.1.1(6,9).0(1,5)]tridecane carbocation + N,N-dimethyl-cadaverine = H(+) + pre-flavunoidine


name: Activated FGFR2 phosphorylates PLCG1 (Canis familiaris)


name: DSH binds to RAC1:GTP (Drosophila melanogaster)


name: 2-aminobut-2-enoate + H2O => L-homoserine


name: H2O + Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine <=> 5'-deoxyadenosine + H(+) + L-methionine + Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester


name: ATM phosphorylates TP53BP1 at DNA DSBs (Bos taurus)


name: ATP + Fe(III)-petrobactin(out) + H2O = ADP + Fe(III)-petrobactin(in) + H(+) + phosphate


name: (3beta,5alpha,17beta)-3-hydroxyandrostan-17-yl sulfate + NADP(+) = 5alpha-dihydrotestosterone sulfate + H(+) + NADPH


name: p-TEFb phosphorylates serine 2 in RNA polymerase II CTD (Homo sapiens)


name: RUNX3 binds SMAD3 and SMAD4 (Drosophila melanogaster)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate


name: L-isoleucine(in) + Na(+)(in) => L-isoleucine(out) + Na(+)(out)


name: p-STAT1dimer:KPNA1 binds KPNB1 (Rattus norvegicus)


name: dodecanoate + sphing-4-enine => H2O + N-dodecanoylsphing-4-enine


name: ABCB9 transports peptides from cytosol to lysosomal lumen (Homo sapiens)


name: Expression of CEBPB in adipogenesis (Homo sapiens)


name: PDE4A hydrolyses cAMP to AMP (Dictyostelium discoideum)


name: 5,10-dihydrophenazine 1-carboxylate + O2 <=> H2O2 + phenazine-1-carboxylate


name: benzoate + H(+) + H2O2 => benzaldehyde + H2O + O2


name: a 1,3-diacyl-sn-glycerol + H2O = a fatty acid + a monoacylglycerol + H(+)


name: (2E,6E)-farnesol + H(+) + NADPH + O2 <=> (2E,6E)-omega-hydroxy-farnesol + H2O + NADP(+)


name: Cleavage and polyadenylation of Intronless Pre-mRNA (Mus musculus)


name: phosphate + propanoyl-CoA = CoA + propanoyl phosphate


name: D-leucine + H2O + O2 = 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: CLCN3 exchanges Cl- for H+ (Homo sapiens)


name: Gamma-carboxy pro-GAS6 transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: dithioerythritol + thiosulfate => cis-1,2-dithiane-4,5-diol + 2 H(+) + hydrogen sulfide + sulfite


name: Dermatan sulfate can be further sulfated on position 2 of iduronate (Rattus norvegicus)


name: Formation of collagen fibrils (Sus scrofa)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Gallus gallus)


name: 3,4-dichloroaniline + malonyl-CoA => CoA + N-(3,4-dichlorophenyl)malonamate


name: PDGF-AB clevage by Furin (Canis familiaris)


name: SERPINC1 binds SERPINC1 activators (Xenopus tropicalis)


name: SHC1 in the RET complex is phosphorylated (Homo sapiens)


name: Formation of RAD52 heptameric ring structure complexes (Bos taurus)


name: MLCL is acylated to CL by HADH (IM) (Mus musculus)


name: TBXAS1 isomerises PGH2 to TXA2 (Sus scrofa)


name: Dimerization of STATs (Canis familiaris)


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Bos taurus)


name: Type B histone acetlytransferase complex acetylates histone H4 (Dictyostelium discoideum)


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 16beta,17beta-dihydroxyandrost-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: RNF8 and RNF168 ubiquitinate H2AFX (Mus musculus)


name: SLC25A32 transports THF from mitochondrial matrix to cytosol (Xenopus tropicalis)


name: P4HB forms mixed disulphides with Hh precursors (Danio rerio)


name: Arachidonate is oxidised to PGG2 by PTGS2 (Homo sapiens)


name: Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Canis familiaris)


name: NTP Binds Active Site of RNA Polymerase II (Mus musculus)


name: p115-RhoGEF activation of RHOA (Mus musculus)


name: 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine => L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + methanol


name: 4-ethyl-2-methoxyphenol + NAD(+) => 2-methoxy-4-vinylphenol + H(+) + NADH


name: a 5'-end adenosine-5'-diphospho-5'-2'-deoxyribonucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + AMP + 2 H(+)


name: trans-Golgi Network Coat Assembly (Homo sapiens)


name: H2O + L-fucono-1,4-lactone <=> H(+) + L-fuconate


name: H2O + 2 monodehydro-L-ascorbate radical + N-decanoyl-(2S)-hydroxyglycine => 2 L-ascorbate + N-decanoylglycine + O2


name: 2-oxoglutarate + beta-alanine <=> 3-oxopropanoate + L-glutamate


name: D-fructopyranose(out) + Na(+)(out) = D-fructopyranose(in) + Na(+)(in)


name: 2-methoxy-6-(all-trans-hexaprenyl)phenol + H(+) + S-adenosyl-L-homocysteine => 3-(all-trans-hexaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine


name: H(+)(out) + L-alanyl-L-valine(out) <=> H(+)(in) + L-alanyl-L-valine(in)


name: 2,3-dimethylsuccinate(out) + 3 Na(+)(out) => 2,3-dimethylsuccinate(in) + 3 Na(+)(in)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Mus musculus)


name: (E)-4-coumarate + H2O <=> 4-hydroxybenzaldehyde + acetate


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Sus scrofa)


name: PREX2 binds PTEN and inhibits it (Gallus gallus)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Sus scrofa)


name: Expression of ABCG1 regulated by NR1H2,3 (Homo sapiens)


name: Phosphorylation of MEF2 proteins by p38 (Bos taurus)


name: (9Z)-octadecenoyl-CoA + H2O => (9Z)-octadecenoate + CoA + H(+)


name: ATP + H(+)(in) + H2O <=> ADP + 2 H(+)(out) + phosphate


name: G-protein alpha subunit is inactivated (Dictyostelium discoideum)


name: 1/3-PP-IP5 transports from the cytosol to the nucleus (Homo sapiens)


name: CDC42:GTP recruits DIAPH2-2 to kinetochores (Rattus norvegicus)


name: Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Sus scrofa)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Mus musculus)


name: CBL ubiquitinates FRS2 and FGFR3 (Mus musculus)


name: 8 CO2 + 9 CoA + 7 H2O + 13 NADP(+) + wortmanamide B => 5-aminopentanoate + acetyl-CoA + 20 H(+) + 8 malonyl-CoA + 13 NADPH


name: 5-hydroxyxanthotoxin + S-adenosyl-L-methionine => isopimpinellin + S-adenosyl-L-homocysteine


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Sus scrofa)


name: GBF1 stimulates ARF nucleotide exchange (Plasmodium falciparum)


name: an L-polyhomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] <=> an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Xenopus tropicalis)


name: Type I Na+-coupled phosphate co-transport (Caenorhabditis elegans)


name: Formation of the SET1A complex (Drosophila melanogaster)


name: PIAS2-1 SUMOylates PARK7 with SUMO1 (Bos taurus)


name: 2 ATP + H(+) <=> diphosphate + P(1),P(4)-bis(5'-adenosyl) tetraphosphate


name: beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + GDP-beta-L-fucose = alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + GDP + H(+)