name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Drosophila melanogaster)


name: diphosphate + N(6)-(dimethylallyl)adenosine 5'-phosphate => AMP + dimethylallyl diphosphate


name: a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol <=> a di-trans,poly-cis-dolichyl phosphate + an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + H(+)


name: NUDT2 hydrolyses GP4G to GTP, GMP (Sus scrofa)


name: AGRN binds Beta amyloid fibril via GAG chains (Sus scrofa)


name: Condensin II complex binds H4K20me1-containing nucleosomes (Homo sapiens)


name: abieta-7,13-dien-18-ol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] => abieta-7,13-dien-18-oate + 3 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (6Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: estrone 3-sulfate(out) + pentanoate(in) <=> estrone 3-sulfate(in) + pentanoate(out)


name: H2O + L-seryl-tRNA(Lys) <=> L-serine + tRNA(Lys)


name: p-Y701-STAT1 binds p-Y705-STAT3 (Caenorhabditis elegans)


name: [thioredoxin]-disulfide + dADP + H2O = [thioredoxin]-dithiol + ADP


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) => 5alpha-androstan-3,17-dione + H(+) + NADPH


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Drosophila melanogaster)


name: 1,2-dihexanoylglycerol + hexadecanoyl-CoA <=> 1,2-dihexanoyl-3-hexadecanoylglycerol + CoA


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecane => 7-tetradecanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Sus scrofa)


name: NTP Binds Active Site of RNA Polymerase II (Saccharomyces cerevisiae)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate => 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: TET3 oxidizes 5-methylcytosine to 5-hydroxymethylcytosine in chromatin containing histone H3.3 (Homo sapiens)


name: RAC1 GAPs stimulate RAC1 GTPase activity (Xenopus tropicalis)


name: CYP8B1 12-hydroxylates 4CHOL7aOLONE (Xenopus tropicalis)


name: NTPDase5 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Canis familiaris)


name: (2E)-13-methyltetradecenal + phosphoethanolamine => 15-methylhexadecasphing-4-enine 1-phosphate


name: H(+) + N(6),N(6)-dimethyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl(79)-[histone H3] + S-adenosyl-L-methionine


name: Diacylgycerol activates Protein kinase C, alpha type (Schizosaccharomyces pombe)


name: an S-polyprenyl-L-cysteine + H2O + O2 => a polyprenal + H2O2 + L-cysteine


name: CHRM2 binds CHRM2 antagonists (Bos taurus)


name: p-T774-PKN1 phosphorylates CDC25C (Saccharomyces cerevisiae)


name: a long-chain fatty aldehyde + FMNH2 + O2 <=> a long-chain fatty acid + FMN + 2 H(+) + H2O + hnu


name: MMAB adenosylates cob(I)alamin (Rattus norvegicus)


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Rattus norvegicus)


name: leukotriene C4 = glutathione + leukotriene A4


name: POLD,POLE binds deISGylated PCNA after TLS (Xenopus tropicalis)


name: biphenyl-2,2',3-triol + O2 = 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + 2 H(+)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + H(+) + NADPH <=> all-trans-lycopaoctaene + 2 diphosphate + NADP(+)


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Drosophila melanogaster)


name: 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + O2 = CO2 + formaldehyde + N(6)-methyl-L-lysyl(4)-[histone H3] + succinate


name: 5-aminopentanamide + H2O <=> 5-aminopentanoate + NH4(+)


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Bos taurus)


name: 4-(dimethylamino)azobenzene + 2 H(+) + 2 NADPH => aniline + N,N-dimethyl-1,4-phenylenediamine + 2 NADP(+)


name: YWHAB dimer dissociates from KSR1:MARK3 (Drosophila melanogaster)


name: high-affinity phosphate:sodium symporter activity


name: erythromycin D + S-adenosyl-L-methionine <=> erythromycin B + H(+) + S-adenosyl-L-homocysteine


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Schizosaccharomyces pombe)


name: Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding (Homo sapiens)


name: RETN gene expression is stimulated by FOXO1 (Homo sapiens)


name: Autophosphorylation of IRAK4 bound to activated TLR5 or 15 (Gallus gallus)


name: ISGylation of host protein filamin B (Drosophila melanogaster)


name: p-S54,92,203-BRF1 binds 14-3-3 (Rattus norvegicus)


name: A + H2O + spermidine = 4-aminobutanal + AH2 + propane-1,3-diamine


name: intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential


name: 3beta-hydroxy-5alpha-androstan-17-one + NADP(+) = 5alpha-androstan-3,17-dione + H(+) + NADPH


name: GluN3A (GRIN3A), GluN3B (GRIN3B) NMDA receptors traffic to the plasma membrane (Homo sapiens)


name: 2-oxoglutarate + L-lysyl-[protein] + O2 = (3S)-3-hydroxy-L-lysyl-[protein] + CO2 + succinate


name: 1,2,3-tri-(9Z,12Z,15Z)-octadecatrienoylglycerol + H2O <=> (9Z,12Z,15Z)-octadecatrienoate + 2,3-di-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycerol + H(+)


name: 2 2-oxoglutarate + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 O2 <=> 2 CO2 + 2 formaldehyde + L-lysyl(27)-[histone H3] + 2 succinate


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Canis familiaris)


name: USP11 deubiquitinates NFKBIA (Homo sapiens)


name: 1D-myo-inositol 1,2,3,6-tetrakisphosphate + phosphate => 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + H2O


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + AMP + diphosphate => (9Z,12Z,15Z)-octadecatrienoate + ATP + CoA


name: Fusion of early-endosome derived vesicles at the TGN (Mus musculus)


name: FMNH2 + O2 <=> 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + dialurate + H(+)


name: Pellino ubiquitinates IRAK1 (Rattus norvegicus)


name: COPII coat binds TRAPPCII and RAB1:GDP (Dictyostelium discoideum)


name: dihydrosterigmatocystin + S-adenosyl-L-methionine <=> 8-O-methyldihydrosterigmatocystin + H(+) + S-adenosyl-L-homocysteine


name: Hv1 Mediated H+ Permeability (Xenopus tropicalis)


name: Collagen type III degradation by MMP15 (Bos taurus)


name: PRC1 SUMOylates CASP8AP2 with SUMO1 (Sus scrofa)


name: deoxycholate + FAD + H(+) + H2O => cholate + FADH2


name: NOX2 generates superoxide anion from oxygen (Homo sapiens)


name: an acyl-CoA + episterol => an episterol ester + CoA


name: genistein + O2 + reduced [NADPH--hemoprotein reductase] => 2'-hydroxygenistein + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: AMP + diphosphate + L-aspartyl-tRNA(Asx) => ATP + L-aspartate + tRNA(Asx)


name: TLR1:TLR2 is recruited to ligand:CD14 (Homo sapiens)


name: Nitric oxide diffuses into the phagosome (Homo sapiens)


name: 2xHSD17B8:2xCBR4 reduces 3OA-ACP to 3HA-ACP (Saccharomyces cerevisiae)


name: (21S)-21-acetoxyl-apo-melianone + O2 + reduced [NADPH--hemoprotein reductase] <=> H(+) + H2O + luvungin A + oxidized [NADPH--hemoprotein reductase]


name: Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Gallus gallus)


name: NEK9 binds NEK6/NEK7 in the cytosol (Caenorhabditis elegans)


name: p-S585-IL3RB binds 14-3-3 proteins (Bos taurus)


name: (2S,4S,5S)-2-amino-6-(3,4-dihydroxyphenyl)-4-hydroxy-5-(methylamino)hexanoyl-[peptidyl-carrier protein] + O2 = (2S,4S)-2-amino-4-[(3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl]-4-hydroxybutanoyl-[peptidyl-carrier protein] + H2O2


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Saccharomyces cerevisiae)


name: guanosine(9) in tRNA + S-adenosyl-L-methionine <=> H(+) + N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Caenorhabditis elegans)


name: SGK phosphorylates SRF (Rattus norvegicus)


name: diacetyl + H(+) + NADH => (R)-acetoin + NAD(+)


name: MLXIPL:MLX binds AGPAT1 gene promoter (Homo sapiens)


name: 3'-phosphoadenylyl sulfate + 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(beta-D-glucuronate) <=> 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: an (11Z)-eicosenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => a (8Z,11Z)-eicosadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: GALNTs transfer GalNAc to Mucins to form Tn antigens (Danio rerio)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Drosophila melanogaster)


name: 5-HEDH dehydrogenates 5-HEPE to 5-oxo-EPA (Homo sapiens)


name: dodecanoyl-CoA + taurine => CoA + H(+) + N-dodecanoyl-taurine


name: Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Caenorhabditis elegans)


name: Iodide is taken up by thyroid epithelial cells (Danio rerio)


name: KIT binds ripretinib (Rattus norvegicus)


name: H2O + N-hexadecanoyl-sn-glycero-3-phosphoethanolamine = H(+) + N-hexadecanoylethanolamine + sn-glycerol 3-phosphate


name: Neurolysin degrades neurotensin (Gallus gallus)


name: 9-hydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => hexadecanoate + O2 + reduced [NADPH--hemoprotein reductase]


name: Formation of the MLL2 complex (Sus scrofa)


name: 2 NADP(+) + tetrahydrocurcumin = curcumin + 2 H(+) + 2 NADPH


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA


name: Maturation of the canonical 20S core particle (Schizosaccharomyces pombe)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Homo sapiens)


name: versiconal hemiacetal acetate reductase activity


name: SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)


name: Binding of Syk tyrosine kinase (Mus musculus)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Xenopus tropicalis)


name: H(+)(out) + oxaloacetate(in) + phosphate(out) => H(+)(in) + oxaloacetate(out) + phosphate(in)


name: CoA + H(+) + N-hexanoyltyramine => hexanoyl-CoA + tyramine


name: SARS-CoV-2 gRNA:RTC:RNA primer binds RTC inhibitors (Homo sapiens)


name: Electron transfer from reduced cytochrome c to molecular oxygen (Bos taurus)


name: IRAK4 recruitment to the activated TLR complexed with ligand, TIRAP and MyD88  (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol => a 1,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: NOX1 complex:RAC1:GTP generates superoxide from oxygen (Rattus norvegicus)


name: ATP + N-(D-erythrulosyl)-cadaverine => ADP + H(+) + N-(3-O-phospho-D-erythrulosyl)-cadaverine


name: NFE2L2 dependent EGF expression (Homo sapiens)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Bos taurus)


name: GLB1 hydrolyses a glycosaminoglycan (Canis familiaris)


name: Exocytosis of secretory granule lumen proteins (Drosophila melanogaster)


name: Caspase-6 translocates to the nucleus (Rattus norvegicus)


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Caenorhabditis elegans)


name: ADP + H(+) + O-phospho-L-threonyl-[myosin heavy-chain] => ATP + L-threonyl-[myosin heavy-chain]


name: PTK6 phosphorylates KHDRBS2 (Rattus norvegicus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1,2-dihexadecanoyl-sn-glycerol + H(+) + phosphocholine


name: (9Z)-octadecenoyl-sn-glycero-3-phosphate + H2O => (9Z-octadecenoyl)-glycerol + phosphate


name: LDL:LDLR complex [plasma membrane] => LDL:LDLR complex [clathrin-coated vesicle] (LDLRAP1-independent) (Mus musculus)


name: HLCS biotinylates ACACB (Rattus norvegicus)


name: SYK activation by SRC (Drosophila melanogaster)


name: 7,8-dihydroneopterin + O2 <=> 7,8-dihydroxanthopterin + formate + glycolaldehyde + H(+)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Homo sapiens)


name: D-alanyl-5'-AMP + holo-[D-alanyl-carrier protein] = AMP + D-alanyl-[D-alanyl-carrier protein] + H(+)


name: LTA4 is converted to EXA4 by ALOX15 (Rattus norvegicus)


name: NPNT from the nephric duct binds ITGA8 on the metanephric mesenchyme (Homo sapiens)


name: Digestion of triacylglycerols by extracellular PTL:colipase (Homo sapiens)


name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Rattus norvegicus)


name: snRNP:Snurportin complex formation (Gallus gallus)


name: Activated STAT3 positively regulates CEBPB transcription (Homo sapiens)


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Homo sapiens)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Canis familiaris)


name: OPTN, TBK1 bind ubiquitinated MOM proteins (Danio rerio)


name: xyloglucan-specific endo-beta-1,4-glucanase inhibitor activity


name: CD320 binds extracellular TCN2:RCbl (Mus musculus)


name: butan-2-one + hydrogen cyanide => 2-hydroxy-2-methylbutanenitrile


name: OGG1 glycosylase mediated recognition and binding of a formamidopyrimidine (FapyG) (Homo sapiens)


name: linalool + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (6E)-8-oxolinalool + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: NFE2L2 dependent NFE2L2 expression (Homo sapiens)


name: PTEN dephosphorylates PIP3 (Mus musculus)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Bos taurus)


name: A + H2O + isoquinoline = AH2 + isoquinolin-1(2H)-one


name: D-ribose + NAD(+) => D-ribono-1,4-lactone + H(+) + NADH


name: p-SLP-76:ADAP binds Ena/VASP (Homo sapiens)


name: NTP Binds Active Site of RNA Polymerase II (Drosophila melanogaster)


name: MTHFD2, D2L oxidise 5,10-methenyl-THF to 10-formyl-THF (Homo sapiens)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] = 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: ATP + hydrogencarbonate + urea = ADP + H(+) + phosphate + urea-1-carboxylate


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Canis familiaris)


name: 2 L-dopa + O2 = 2 3-(3,4-dihydroxyphenyl)pyruvate + 2 NH4(+)


name: MAOA:FAD oxidatively deaminates of 5HT (Sus scrofa)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Dictyostelium discoideum)


name: CUBN:AMN-mediated CBLIF:RCbl uptake and delivery to lysosome (Rattus norvegicus)


name: MET phosphorylates SHC1-2 (Xenopus tropicalis)


name: ADRM1 binds 26S proteasome (Caenorhabditis elegans)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Rattus norvegicus)


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Canis familiaris)


name: all-trans-(4S,16)-dihydroxyretinoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => all-trans-(4S)-hydroxyretinoate + O2 + reduced [NADPH--hemoprotein reductase]


name: AMP + H2O => IMP + NH4+ (AMPD) (Homo sapiens)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Gallus gallus)


name: LTA4 is hydolysed to LTB4 by LTA4H (Dictyostelium discoideum)


name: Formation of NR-NCOR Corepressor Complex (Caenorhabditis elegans)


name: Exogenous soluble antigen targeted to more stable early endosome (Mus musculus)


name: acacetin + H(+) + S-adenosyl-L-homocysteine => apigenin + S-adenosyl-L-methionine


name: 22-oxodocosanoate + H2O + NAD(+) = docosanedioate + 2 H(+) + NADH


name: Oxidation of cholesterol to 22beta-hydroxycholesterol (Bos taurus)


name: 2-acyl LPC is acylated to PC by LPCAT (Plasmodium falciparum)


name: ADP + H(+) + L-cysteine(in) + phosphate => ATP + H2O + L-cysteine(out)


name: Contactin-1 (CNTN1) binds NOTCH1 (Homo sapiens)


name: PRMT1 arginine-methylates RUNX1 (Bos taurus)


name: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine => a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Drosophila melanogaster)


name: EXT1:EXT2 transfers GlcNAc to the terminal GlcA residue (Danio rerio)


name: 15-methylhexadecasphinganine + NADP(+) = 3-dehydro-15-methylhexadecasphinganine + H(+) + NADPH


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Homo sapiens)


name: acetyl-CoA + L-leucine => CoA + H(+) + N-acetyl-L-leucine


name: H(+)(in) + L-tryptophan(in) = H(+)(out) + L-tryptophan(out)


name: 4-chlorobenzoyl-CoA + chloride + NADP(+) => 2,4-dichlorobenzoyl-CoA + NADPH


name: 4-methylpentanoate + CoA + H(+) => 4-methylpentanoyl-CoA + H2O


name: Androgens binds AR (in the HSP90 chaperone complex) (Rattus norvegicus)


name: Acitretin binds to RAR:RXR (Gallus gallus)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Mus musculus)


name: a D-alpha-amino acid => an L-alpha-amino acid


name: Importin-8 binds AGO2:miRNA (Schizosaccharomyces pombe)


name: HCO3- transport through ion channel (Sus scrofa)


name: SH pentamer transports K+ (Homo sapiens)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Bos taurus)


name: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate


name: GSTs transfer GSH to NAPQI to form APAP-SG (Danio rerio)


name: Autocleavage of ADGRG6 (Caenorhabditis elegans)


name: 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol => 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoate + A + H2O


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Caenorhabditis elegans)


name: GSTK1 dimer transfers GS from GSH to CDNB (Bos taurus)


name: Activation of recruited TAK1 (Gallus gallus)


name: CYP2F1 dehydrogenates 3-methylindole (Rattus norvegicus)


name: Activated NTRK2 binds FRS2 (Rattus norvegicus)


name: chloride(in) + N-methyl-L-proline(in) + 2 Na(+)(in) => chloride(out) + N-methyl-L-proline(out) + 2 Na(+)(out)


name: HEXB cleaves the terminal GalNAc from DS (Drosophila melanogaster)


name: cholesteryl (9Z-octadecenoate)(out) => cholesteryl (9Z-octadecenoate)(in)


name: acetyl-CoA + propanoate <=> acetate + propanoyl-CoA


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Xenopus tropicalis)


name: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA


name: A + H2O + NH4(+) = AH2 + H(+) + hydroxylamine


name: MMACHC:cob(II)alamin binds MMADHC (Caenorhabditis elegans)


name: a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: creatinine(out) + H(+)(in) => creatinine(in) + H(+)(out)


name: BCL2L11 (BIM) gene transcription is stimulated by RUNX3 (Homo sapiens)


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Sus scrofa)


name: estrone + O2 + reduced [NADPH--hemoprotein reductase] => 4-hydroxyestrone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Canis familiaris)


name: NEDD8:AcM-UBE2M binds CUL9:RBX1 ubiquitin ligase complex (Canis familiaris)


name: Phosphorylated KHDRBS1 translocates to the cytosol (Bos taurus)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + H(+) + S-adenosyl-L-homocysteine


name: (S)-lactate(in) + Na(+)(in) => (S)-lactate(out) + Na(+)(out)


name: SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Homo sapiens)


name: Cdc6 protein is phosphorylated by CDK (Caenorhabditis elegans)


name: CYB5Rs reduce MetHb to HbA (Xenopus tropicalis)


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)


name: gamma-secretase cleaves EPHB2 (Drosophila melanogaster)


name: oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor


name: C-20 gibberellin 2-beta-dioxygenase activity


name: a ganglioside Gal(Fuc)-GD1b (d18:1(4E)) + GDP + H(+) => a ganglioside Gal-GD1b (d18:1(4E)) + GDP-beta-L-fucose


name: 1-eicosanoylglycerol + H2O => eicosanoate + glycerol + H(+)


name: ergothioneine(out) + Na(+)(out) = ergothioneine(in) + Na(+)(in)


name: GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + H(+) + NADPH => GDP-beta-L-colitose + NADP(+)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Homo sapiens)


name: MAPKs phosphorylate ETS1 and ETS2 (Danio rerio)


name: Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Sus scrofa)


name: IRAK1 or IRAK2 binds to the activated IRAK4 :activated TLR:MyD88:TIRAP complex (Homo sapiens)


name: levoglucosan + NAD(+) <=> 3-dehydrolevoglucosan + H(+) + NADH


name: H(+) + rebaudioside E + UDP => stevioside + UDP-alpha-D-glucose


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Xenopus tropicalis)


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Dictyostelium discoideum)


name: FYN phosphorylates PAK2 (Xenopus tropicalis)


name: digallate + H2O <=> 2 3,4,5-trihydroxybenzoate + H(+)


name: (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA => (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol


name: L-arginine(in) + N(omega)-methyl-L-arginine(out) => L-arginine(out) + N(omega)-methyl-L-arginine(in)


name: (S)-malate + a quinone => a quinol + oxaloacetate


name: "Transferring aldehyde or ketonic groups"


name: 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase] => AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase]


name: HGSNAT oligomer acetylates Heparan chain(1) (Canis familiaris)


name: CD151 interacts with BP180 and the integrin alpha 6 subunit (Mus musculus)


name: Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4) (Sus scrofa)


name: Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (Xenopus tropicalis)


name: RABGGTA and RABGGTB bind (Caenorhabditis elegans)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)


name: CO + H(+) + N-acetylanthranilate => 3-hydroxy-2-methyl-1H-quinolin-4-one + O2


name: a long-chain fatty acyl-CoA + acetyl-CoA = a long-chain 3-oxo-fatty acyl-CoA + CoA


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Mus musculus)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Rattus norvegicus)


name: 2 Na(+)(out) + thymidine(out) => 2 Na(+)(in) + thymidine(in)


name: a cytidine in mRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Drosophila melanogaster)


name: (3R)-hydroxy-(15Z)-tetracosenoyl-CoA = (2E,15Z)-tetracosadienoyl-CoA + H2O


name: 1D-myo-inositol 2,4,5-triphosphate + H2O = 1D-myo-inositol 2,5-bisphosphate + phosphate


name: 5,6,7,8-tetrahydromethanopterin + H(+) + N-formylmethanofuran <=> methanofuran + N(5)-formyl-5,6,7,8-tetrahydromethanopterin


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 5-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a cytidine in rRNA + S-adenosyl-L-methionine = an N(4)-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: RNF41 binds neuregulin-activated ERBB3 (Drosophila melanogaster)


name: SEC4C,D bind GOSR2 and STX5 (Caenorhabditis elegans)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc derivative + CMP + H(+)


name: Caspase-mediated cleavage of PKC theta (Mus musculus)


name: ARSA removes sulfate from PSAP(195-273):Sulfatide (Sus scrofa)


name: 3-hydroxyphenylacetate + H(+) + NADPH + O2 => H2O + homogentisate + NADP(+)


name: HHAT palmitoylates Hh N-terminal fragment (Xenopus tropicalis)


name: Membrane-bound GISH binds to ARR receptor complex (Drosophila melanogaster)


name: GBF1 stimulates nucleotide exchange on ARF4 (Dictyostelium discoideum)


name: GDP-4-dehydro-alpha-D-rhamnose + H2O => GDP-alpha-D-mannose


name: GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Canis familiaris)


name: erythritol + NADP(+) = D-erythrose + H(+) + NADPH


name: 2 chloride(out) + K(+)(out) + Na(+)(out) = 2 chloride(in) + K(+)(in) + Na(+)(in)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Mus musculus)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Caenorhabditis elegans)


name: (2E)-hexadecenoyl-CoA + H(+) + NADPH <=> hexadecanoyl-CoA + NADP(+)


name: FDPS dimer transfers IPPP to GPP (Drosophila melanogaster)


name: Carbonic anhydrase dehydrates bicarbonate (cytosol) (Danio rerio)


name: PGM2:Mg2+ isomerises  dR1P to dR5P (Caenorhabditis elegans)


name: NH4(+) + S-methyl-5'-thioinosine => H(+) + H2O + S-methyl-5'-thioadenosine


name: Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Mus musculus)


name: Kinetochore capture of astral microtubules (Rattus norvegicus)


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Schizosaccharomyces pombe)


name: (S)-reticuline + O2 + reduced [NADPH--hemoprotein reductase] <=> (S)-corytuberine + 2 H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: USP44 deubiquitinates CDC20 (Homo sapiens)


name: ADP + D-glucosamine => AMP + D-glucosamine 6-phosphate + H(+)


name: NPM2 and HIRA bind p-S9-PRM1:dsDNA (Homo sapiens)


name: STAT3 is phosphorylated downstream of active ALK (Mus musculus)


name: Cross-linking of FCGRIIA with IgG-coated Ag (Homo sapiens)


name: arsenate(in) + H(+)(in) <=> arsenate(out) + H(+)(out)


name: 2 S-adenosyl-L-methionine + sphing-4-enine <=> 2 H(+) + N,N-dimethylsphing-4-enine + 2 S-adenosyl-L-homocysteine


name: 2 H(+) + N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine => L-lysine + 2 S-adenosyl-L-methionine


name: MAPKAPK2 phosphorylates HSF1 (Mus musculus)


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Sus scrofa)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Caenorhabditis elegans)


name: NEIL1 cleaves FapyG from damaged DNA (Canis familiaris)


name: H(+)(out) + L-methionine(in) <=> H(+)(in) + L-methionine(out)


name: AMP + diphosphate + diphthamide-[translation elongation factor 2] + H(+) => ATP + diphthine-[translation elongation factor 2] + NH4(+)


name: an aromatic aldehyde + H(+) + NADPH => an aromatic primary alcohol + NADP(+)


name: AHR:TCDD binds ARNT (Drosophila melanogaster)


name: a long-chain fatty acyl-CoA + alpha,alpha-trehalose => 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + CoA


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Gallus gallus)


name: 2-furoate + 2 H(+) + NADH => furfural + H2O + NAD(+)


name: acetyl-CoA + N-terminal L-methionyl-[transmembrane protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-[transmembrane protein]


name: "N-terminal methionine N(alpha)-acetyltransferase NatF"


name: COQ2 ligates all-E-10PrP2 to PHB (Homo sapiens)


name: 7,8-dimethoxyflavone + H(+) + S-adenosyl-L-homocysteine => 8-hydroxy-7-methoxyflavone + S-adenosyl-L-methionine


name: PGH2 is isomerised to PGD2 by HPGDS (Drosophila melanogaster)


name: c-src associates with Cx43 in gap junctions (Mus musculus)


name: a medium-chain primary fatty alcohol + NADP(+) = a medium-chain fatty aldehyde + H(+) + NADPH


name: N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + O2 + reduced [NADPH--hemoprotein reductase] => 2-oxo-N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: KEN dimer represses transcription (Drosophila melanogaster)


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Rattus norvegicus)


name: ATP + cob(I)inamide-[corrinoid adenosyltransferase] = adenosylcob(III)inamide + apo-[corrinoid adenosyltransferase] + triphosphate


name: 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol


name: ATP + hypotaurocyamine => ADP + H(+) + N(omega)-phosphohypotaurocyamine


name: KIR2DS1 interacting with HLA-C group 2 (Cw4) (Sus scrofa)


name: bradykinin(1-8) + H2O = bradykinin(1-7) + L-phenylalanine


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Canis familiaris)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Bos taurus)


name: 2-oxoglutarate + L-lysine <=> (S)-2-amino-6-oxohexanoate + L-glutamate


name: H(+) + NADPH + O2 + pentachlorophenol = 2,3,5,6-tetrachloro-1,4-benzoquinone + chloride + H2O + NADP(+)


name: N-hydroxy-L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + N,N-dihydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: LPL hydrolyses TGs from mature CMs (Rattus norvegicus)


name: 4-hydroxyestrone + S-adenosyl-L-methionine = 4-methoxyestrone + H(+) + S-adenosyl-L-homocysteine


name: (2E,6E)-farnesyl diphosphate => diphosphate + longifolene


name: Displacement of MPG glycosylase by APEX1 at the AP site (Canis familiaris)


name: Spermine  => N-acetylated spermine (Sus scrofa)


name: (Z)-phenylacetaldehyde oxime => H2O + phenylacetonitrile


name: n adenosine 3',5'-bisphosphate + chondroitin 4',6'-bissulfate + n H(+) => n 3'-phosphoadenylyl sulfate + chondroitin 4'-sulfate


name: HSD2B1 dimer, HSD3B2 dimer isomerise DHA to ANDST (Sus scrofa)


name: Internalization of gap junction plaques (Homo sapiens)


name: NT5C2 tetramer dephosphorylates RBV-MP (Canis familiaris)


name: (2R,3S)-3-isopropylmalate(out) + sulfate(in) => (2R,3S)-3-isopropylmalate(in) + sulfate(out)


name: an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol = 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Rattus norvegicus)


name: Phosphorylated FOXO3 translocates to the nucleus (Homo sapiens)


name: RSF complex binds the centromere (Sus scrofa)


name: a 1,2-diacylglycerol + a fatty acid + H(+) => a triacylglycerol + H2O


name: acetyl-CoA + N-terminal L-seryl-[protein] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-seryl-[protein]


name: 1-acyl LPI is acylated to PI by MBOAT7 (Xenopus tropicalis)


name: ADP + glutathione(out) + glycoursodeoxycholate(out) + H(+) + phosphate => ATP + glutathione(in) + glycoursodeoxycholate(in) + H2O


name: (1S,5S)-alpha-pinene + H(+) + NADH + O2 => alpha-pinene oxide + H2O + NAD(+)


name: a uridine in rRNA + S-adenosyl-L-methionine => a 2'-O-methyluridine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Danio rerio)


name: 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(in) + glutarate(out) => 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(out) + glutarate(in)


name: (R)-2-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate + H(+) => (8Z,11Z,14Z)-heptadecatrienal + CO2 + H2O


name: RTC synthesizes SARS-CoV-2 plus strand genomic RNA (Homo sapiens)


name: Active FLT3 binds to CBL (Canis familiaris)


name: (2S)-ethylmalonyl-CoA + H(+) <=> butanoyl-CoA + CO2


name: MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Plasmodium falciparum)


name: (Z)-2-phenyl-1-thioacetohydroximate + UDP-alpha-D-glucose <=> (Z)-desulfoglucotropeolin + UDP


name: Isomerization of 3-trans-decenoyl-CoA to form trans-dec-2-enoyl-CoA (Rattus norvegicus)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Sus scrofa)


name: (R)-lactaldehyde + 3-hydroxypyruvate <=> (3S,4R,5R)-3,4,5-trihydroxy-2-oxohexanoate


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Sus scrofa)


name: p-ULK1 phosphorylates DENND3 (Schizosaccharomyces pombe)


name: 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + H(+) + UDP => 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Homo sapiens)


name: thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Danio rerio)


name: 1',3'-bis[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O = (9Z)-octadecenoate + 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H(+)


name: UV-DDB ubiquitinates XPC (Gallus gallus)


name: LTA4 is converted to EXA4 by ALOX15 (Sus scrofa)


name: MAP1LC3B binds p-S-OPTN bound to Ub-mitochondria  (Bos taurus)


name: kaempferol + S-adenosyl-L-methionine <=> H(+) + kaempferol 7-methyl ether + S-adenosyl-L-homocysteine


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Rattus norvegicus)


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Schizosaccharomyces pombe)


name: MCPH1 sequesters condensin II (Bos taurus)


name: Binding of AP1 transcriptional activator complexes to CCND1 promoter (Canis familiaris)


name: Expression of SALL1 in metanephric mesenchyme (Homo sapiens)


name: Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Mus musculus)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Schizosaccharomyces pombe)


name: ASICs bind STOML3, (STOM) (Homo sapiens)


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Homo sapiens)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Sus scrofa)


name: ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Mus musculus)


name: UDP-beta-L-arabinofuranose(in) + UMP(out) <=> UDP-beta-L-arabinofuranose(out) + UMP(in)


name: KIF17 enters the cilium (Drosophila melanogaster)


name: 2-formylglutarate + NH4(+) => 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H2O


name: 3 a menaquinol + protoporphyrin IX => 3 a menaquinone + protoporphyrinogen IX


name: curcumin + 2 H(+) + 2 NADPH => 2 NADP(+) + tetrahydrocurcumin


name: adenosylcob(III)alamin 5'-phosphate + GMP + H(+) => adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Canis familiaris)


name: p-VAV family:PIP3 binds RAC1:GDP (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acyl-(4R)-4-hydroxysphinganine = a 1,2-diacyl-sn-glycerol + an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol


name: GTP + L-seryl-[protein] <=> GDP + H(+) + O-phospho-L-seryl-[protein]


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Xenopus tropicalis)


name: AcK685-pY705,S727 STAT3 dimer binds DNMT1 promoter (Homo sapiens)


name: 2-acyl LPS is acylated to PS by LPSAT (Drosophila melanogaster)


name: Phosphorylation and activation of eIF4G by activated S6K1 (Canis familiaris)


name: CNRs bind CNR agonists (Canis familiaris)


name: IL4:IL4R:JAK2 binds IL2RG:JAK3 (Sus scrofa)


name: 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate => 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O


name: DNA polymerase epsilon binds at the origin (Canis familiaris)


name: Furin cleaves pro-BGLAP to BGLAP (Xenopus tropicalis)


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Schizosaccharomyces pombe)


name: gamma-L-glutamyl-L-cysteine + hercynine + O2 = gamma-L-glutamyl-hercynylcysteine S-oxide + H2O


name: "gamma-glutamyl hercynylcysteine S-oxide synthase"


name: CTP + D-ribitol 5-phosphate + H(+) => CDP-L-ribitol + diphosphate


name: EGFR phosphorylates EPS15 (Rattus norvegicus)


name: N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,hepta-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-galactosamine = H(+) + N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + UDP


name: 4-hydroxyphenylglyoxylate + L-glutamate => 2-oxoglutarate + D-4-hydroxyphenylglycine


name: Caspase-mediated cleavage of E-Cadherin (Danio rerio)


name: 1-(9S,13S-12-oxo-10,15Z-phytodienoyl)-2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = (9S,13S,15Z)-12-oxophyto-10-15-dienoate + 2-(7Z,10Z,13Z)-hexadecatrienoyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+)


name: a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose => a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP


name: TetraHCA is translocated from the mitochondrial matrix to the cytosol (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H(+) + phosphocholine


name: H2O + N-dodecanoylsphing-4-enine <=> dodecanoate + sphing-4-enine


name: USP5 cleaves polyubiquitin (Dictyostelium discoideum)


name: cadmium ion transmembrane transporter activity


name: JMJD1C demethylates H3K9 mono- and di-methylation (Rattus norvegicus)


name: 1-O-(trans-cinnamoyl)-beta-D-glucose + an alcohol => an alkyl cinnamate + beta-D-glucose


name: (2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + H2O => (R)-glycerate + D-glucose


name: DDR2 binds collagen type I, II, III, V, X fibrils (Homo sapiens)


name: sulfate(out) + sulfite(in) => sulfate(in) + sulfite(out)


name: VAV exchanges GTP for GDP on RAC1, activating it (Mus musculus)


name: SUMOylation of DNMT3B with SUMO1 (Sus scrofa)


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Xenopus tropicalis)


name: glutarate(in) + prostaglandin E2(out) = glutarate(out) + prostaglandin E2(in)


name: Carbonic anhydrase hydrates carbon dioxide (cytosol) (Plasmodium falciparum)


name: 3-dehydrolevoglucosan + H(+) + NADH => levoglucosan + NAD(+)


name: trans-3-hydroxy-L-proline <=> 1-pyrroline-2-carboxylate + H2O


name: CO2 + 2 Fe(II)-[cytochrome c553] + H(+) => 2 Fe(III)-[cytochrome c553] + formate


name: O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + H(+) + UDP


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: 1,2-ditetradecanoyl-sn-glycerol + ATP <=> 1,2-ditetradecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: CHM binds RGGT (Saccharomyces cerevisiae)


name: FLT3 mutant dimers:GRB2 bind SOS1 (Homo sapiens)


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Plasmodium falciparum)


name: Active PLC-gamma1 dissociates from EGFR (Danio rerio)


name: Co(2+)(out) + 2 hydrogencarbonate(out) => Co(2+)(in) + 2 hydrogencarbonate(in)


name: p-S446-IRF5 dimer translocates to the nucleus (Sus scrofa)


name: fibrinogen -> fibrin monomer + 2 fibrinopeptide A + 2 fibrinopeptide B (Gallus gallus)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine => 3-O-(beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + H(+) + UDP


name: 2-oxoglutarate + heptyl sulfate + O2 => CO2 + H(+) + heptanal + succinate + sulfate


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Danio rerio)


name: (2R)-2-phosphoglycerate + H2O <=> (R)-glycerate + phosphate


name: The primase component of DNA polymerase:primase synthesizes a 6-10 nucleotide RNA primer on the G strand of the telomere (Sus scrofa)


name: Formation of classic pathway C5 convertase (Rattus norvegicus)


name: STK11 (LKB1) phosphorylates NUAK1 (Homo sapiens)


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Homo sapiens)


name: AHR:2xHSP90:AIP:PTGES3 binds TCDD (Homo sapiens)


name: H2O + N-methyl-2-methylpropanamine + NAD(+) <=> 2-methylpropanal + H(+) + methylamine + NADH


name: glyoxalase (glycolic acid-forming) activity


name: Transcription of respiratory syncytial virus subgenomic positive sense mRNAs (Homo sapiens)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Bos taurus)


name: Phosphopantetheine conjugation of the ACP domain of FAS (Homo sapiens)


name: [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O


name: DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A (Homo sapiens)


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Rattus norvegicus)


name: L-cysteine(in) + L-phenylalanine(out) => L-cysteine(out) + L-phenylalanine(in)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Gallus gallus)


name: ent-copalyl diphosphate => diphosphate + ent-pimara-9(11),15-diene


name: AOX1 oxidises PXL to PDXate (Drosophila melanogaster)


name: a uridine in 21S rRNA + S-adenosyl-L-methionine <=> a 2'-O-methyluridine in 21S rRNA + H(+) + S-adenosyl-L-homocysteine


name: H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-L-phenylalanine => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + L-phenylalanine


name: DAG and Ca+2 bind to PKC and tether it to membrane (Rattus norvegicus)


name: (S)-malate(out) + glycolate(in) => (S)-malate(in) + glycolate(out)


name: Recruitment of HDAC1 by p130 (RBL2) (Gallus gallus)


name: (24S)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> 24S,25-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ULK3:SUFU dissociates (Drosophila melanogaster)


name: 3-methylquinoline + A + H2O => 3-methylquinolin-2(1H)-one + AH2


name: Release of novel PDGFs as latent factors (Drosophila melanogaster)


name: STAB1 (FEEL-1) binds ligands (Homo sapiens)


name: IL6R binds IL6R inhibitors (Rattus norvegicus)


name: SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Plasmodium falciparum)


name: KCNJs transport K+ from the extracellular region to cytosol (Danio rerio)


name: 2'-aminobiphenyl-2,3-diol + NAD(+) => 9H-carbazole + H(+) + NADH + O2


name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Danio rerio)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Homo sapiens)


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Canis familiaris)


name: (22R)-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] <=> (22R,7alpha)-dihydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH


name: Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: TCN2 binds RCbl in the circulation (Drosophila melanogaster)


name: (9Z,12Z)-octadecadienoate + 1-octadecanoyl-sn-glycerol + H(+) => 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + H2O


name: 2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + hexadecanoate => 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O


name: MCM4, MCM6 and MCM7 form a heterotrimer (Caenorhabditis elegans)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Mus musculus)


name: Nectin-1:Nectin-4 trans heterodimer formation (Drosophila melanogaster)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-heptadecanoyl-sn-glycero-3-phosphate = 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Plasmodium falciparum)


name: LIPT2 transfers octanoyl group to GCSH (Gallus gallus)


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Xenopus tropicalis)


name: Linkage of L1 with treadmilling F-actin (Mus musculus)


name: H(+) + N(5)-methyl-L-glutaminyl-[protein] + S-adenosyl-L-homocysteine => L-glutaminyl-[protein] + S-adenosyl-L-methionine


name: LONP1 binds mitochondrial inner membrane proteins (Homo sapiens)


name: L-glutamate gamma-semialdehyde <=> L-1-pyrroline-5-carboxylate (Homo sapiens)


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Danio rerio)


name: FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Homo sapiens)


name: (2E)-dodecenedioyl-CoA + H2O = (3S)-hydroxydodecanedioyl-CoA


name: 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(beta-D-glucuronate)


name: acetyl-CoA + D-tryptophan => CoA + H(+) + N-acetyl-D-tryptophan


name: (2R,3S)-piscidate + (E)-sinapoyl-CoA <=> cimicifugate J + CoA


name: PAK1,2,3 phosphorylates MAPK6,4 (Canis familiaris)


name: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)


name: [protein]-C-terminal Gly-Gly-AMP + diphosphate => [protein]-C-terminal Gly-Gly + ATP + H(+)


name: L-cystine => 2-aminoprop-2-enoate + S-sulfanyl-L-cysteine


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2M (Gallus gallus)


name: Binding of ADAR2 homodimer to dsRNA duplex (Sus scrofa)


name: 1,3,5-trihydroxybenzene + 2,4-diacetylphloroglucinol + H(+) => 2 2-acetylphloroglucinol


name: dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2 S-adenosyl-L-methionine = dTDP-D-ravidosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: NTPDase1 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)


name: [protein]-C-terminal L-amino acid-glycyl-phosphatidylserine + H2O => 1,2-diacyl-sn-glycero-3-phospho-L-serine-N-glycine + [protein]-C-terminal <stereo>L-</stereo>amino acid


name: (S)-eriodictyol + 2-oxoglutarate + O2 = (2R,3R)-dihydroquercetin + CO2 + succinate


name: 2-oxoglutarate + O2 + thebaine <=> 6-O-demethylthebaine + CO2 + formaldehyde + H(+) + succinate


name: Fibrillin C-terminal processing (Danio rerio)


name: GRB2:SOS1 complex binds phosphorylated EGFR:ERBB2 heterodimer (Homo sapiens)


name: ATP + hydrogencarbonate + tetracosanoyl-CoA = 2-carboxytetracosanoyl-CoA + ADP + H(+) + phosphate


name: SUMOylation of ING2 with SUMO1 (Sus scrofa)


name: (S)-cheilanthifoline + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (S)-scoulerine + O2 + reduced [NADPH--hemoprotein reductase]


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Xenopus tropicalis)


name: Aquaporin-7 passively transports glycerol out of cell (Mus musculus)


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Caenorhabditis elegans)


name: Release of STAT1 dimer from active receptor unit (Gallus gallus)


name: BSG (basigin) binds Integrin alpha3beta1, alpha6beta1 (Canis familiaris)


name: FRS2 binds to active TrkA receptor (Bos taurus)


name: cyclohexanecarbaldehyde + hydrogen cyanide => (2S)-2-cyclohexyl-2-hydroxyacetonitrile


name: (+)-copalyl diphosphate + H2O = 13-epi-manool + diphosphate


name: NADP(+) + prostaglandin E2 => 15-oxoprostaglandin E2 + H(+) + NADPH


name: TRAF6 polyubiquitinates NRIF (Bos taurus)


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: H(+) + L-rhamnono-1,4-lactone + NADPH => L-rhamnofuranose + NADP(+)


name: SRXN1 reduces hyperoxidized PRDX1 dimer (Mus musculus)


name: (9Z)-tetradecenoyl-CoA + (R)-carnitine = CoA + O-(9Z)-tetradecenoyl-(R)-carnitine


name: IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)


name: PANK2 phosphorylates PanK (Drosophila melanogaster)


name: Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Drosophila melanogaster)


name: MMAB adenosylates cob(I)alamin (Sus scrofa)


name: (S)-3-hydroxybutanoate + 2-oxoglutarate => (R)-2-hydroxyglutarate + acetoacetate


name: PIAS4 SUMOylates TP53BP1 with SUMO1 (Saccharomyces cerevisiae)


name: SLC16A10-mediated uptake of aromatic amino acids (Dictyostelium discoideum)


name: Phosphorylated heterodimers of ERBB2 KD mutants and EGFR, in complex with GRB2:GAB1, bind PI3K (Homo sapiens)


name: a 2-hydroxyflavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => a flavanone + O2 + reduced [NADPH--hemoprotein reductase]


name: FLAD1 phosphorylates FMN (Dictyostelium discoideum)


name: crocetin + UDP-alpha-D-glucose => beta-D-glucosyl crocetin + UDP


name: 2xTRAP hydrolyzes FMN to RIB (Danio rerio)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Plasmodium falciparum)


name: PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Caenorhabditis elegans)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine => N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine


name: SDH complex dehydrogenates succinate (Rattus norvegicus)


name: O-methyl gibberellin A4 + S-adenosyl-L-homocysteine => gibberellin A4 + S-adenosyl-L-methionine


name: AGO2 cleaves passenger strand of duplex siRNA (Drosophila melanogaster)


name: RIC1:RGP1 stimulates nucleotide RAB6 nucleotide exchange (Saccharomyces cerevisiae)


name: PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA (Mus musculus)


name: S-Adenosyl methionine <=> Decarboxylated-Adenosyl methionine + CO2 (Saccharomyces cerevisiae)


name: glutarate(in) + succinate(out) <=> glutarate(out) + succinate(in)


name: Na(+)(out) + thymine(out) <=> Na(+)(in) + thymine(in)


name: PGAM dimers (PGAM1,2) isomerise 2PG to 3PG (Drosophila melanogaster)


name: Addition of galactose by beta 4-galactosyltransferases (Homo sapiens)


name: NFE2L2 translocates from cytosol to nucleoplasm (Xenopus tropicalis)


name: ALKBH3 in complex with ASCC1:ASCC2:ASCC3 binds alkylated DNA containing 1-etA (Homo sapiens)


name: RNA Pol II initiates transcription from damaged DNA template (Mus musculus)


name: PGRMC2:Hemes dissociates (Rattus norvegicus)


name: NEIL3 cleaves spiroiminodihydantoin (Bos taurus)


name: Caspase-1 active tetramer formation (Sus scrofa)


name: NEDD4L ubiquitinates SMAD2/3 (Homo sapiens)


name: NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Caenorhabditis elegans)


name: 2 Fe(III)-[cytochrome b5] + H2O + N-tetracosanoyl-(4R)-hydroxysphinganine => 2 Fe(II)-[cytochrome b5] + 2 H(+) + N-tetracosanoylsphinganine + O2


name: gibberellin A4 + S-adenosyl-L-methionine => O-methyl gibberellin A4 + S-adenosyl-L-homocysteine


name: G alpha (q) inhibits PI3K alpha (Homo sapiens)


name: dihydroprecondylocarpine acetate + NADPH = (+)-vincadifformine + acetate + NADP(+)


name: (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + H2O <=> (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + phosphate


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Sus scrofa)


name: MAPK1 phosphorylates SOX10 (Danio rerio)


name: H2O + pyridoxal 5'-phosphate = phosphate + pyridoxal


name: acetate + ATP + holo-[ACP] = acetyl-[ACP] + AMP + diphosphate


name: ASPA deacetylates NAA to acetate and L-aspartate (Xenopus tropicalis)


name: H2O + N(6)-hexanoyl-L-lysyl-[protein] + NAD(+) <=> 2''-O-hexanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: a (3R)-3-hydroxyacyl-CoA + NADP(+) => a 3-oxoacyl-CoA + H(+) + NADPH


name: [DsrC protein]-dithiol + 2 AH2 + 2 H(+) + sulfite => [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 2 A + 3 H2O


name: H2O + NAD(+) + succinate semialdehyde => 2 H(+) + NADH + succinate


name: (2E,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H(+) + NADPH => (11Z,14Z,17Z)-eicosatrienoyl-CoA + NADP(+)


name: 26S proteasome processes p-7S-p100:RELB to form p52:RELB (Mus musculus)


name: Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Sus scrofa)


name: 6-carboxyhexanoyl-CoA + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + CoA


name: NAD(+) + prephenate = 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH


name: fluoroacetaldehyde + L-threonine <=> 4-fluoro-L-threonine + acetaldehyde


name: putrescine + S-adenosyl 3-(methylsulfanyl)propylamine => H(+) + S-methyl-5'-thioadenosine + spermidine


name: OTULIN,USP5 cleaves UBB yielding ubiquitin (Dictyostelium discoideum)


name: Activation of proMMP7 by MMP3 (Sus scrofa)


name: H(+) + malonyl-[ACP] + tetradecanoyl-[ACP] <=> 3-oxohexadecanoyl-[ACP] + CO2 + holo-[ACP]


name: H(+) + O-(beta-L-arabinofuranosyl)-trans-4-hydroxy-L-prolyl-[protein] + UDP => trans-4-hydroxy-L-prolyl-[protein] + UDP-beta-L-arabinofuranose


name: all-trans-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + all-trans-retinal


name: BIL binds GSTA1, FABP1 (Rattus norvegicus)


name: (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 H(+) + O2 + 2 reduced [adrenodoxin] => (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + 2 H2O + 2 oxidized [adrenodoxin]


name: germacra-1(10),4,11(13)-trien-12-oate + O2 + reduced [NADPH--hemoprotein reductase] <=> 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Formation of the PA28-alpha-beta-20S proteasome (Rattus norvegicus)


name: Displacement of MBD4 glycosylase by APEX1 at the AP site (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H(+) + hexadecanoate


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Bos taurus)


name: chloride(out) + nitrate(in) => chloride(in) + nitrate(out)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = H(+) + hexadecanoate + sn-glycero-3-phosphoethanolamine


name: BIL dissociates from GSTA1, FABP1 (Caenorhabditis elegans)


name: GDP + methylglyoxal => N(2)-(1-hydroxy-2-oxopropyl)-GDP


name: Cleavage of ethenoadenine by MPG glycosylase (Homo sapiens)


name: Cleavage of formamidopyrimidine (FapyA) by NTHL1 glycosylase  (Schizosaccharomyces pombe)


name: 4-chlorophenylacetate + NADH + O2 => 3,4-dihydroxyphenylacetate + chloride + NAD(+)


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Rattus norvegicus)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Gallus gallus)


name: PHLPP dephosphorylates S473 in AKT (Mus musculus)


name: NEDD8-STON binds TOR1 hexamer and COP9 complex (Danio rerio)


name: bis-D-fructose 2',1:2,1'-dianhydride + H2O <=> inulobiose


name: PLCG2 translocates from cytosol to plasma membrane (Rattus norvegicus)


name: 2 biliverdin IXalpha + 2 H2O => 2 (4Z,15Z)-bilirubin IXalpha + O2


name: 3'-phosphoadenylyl sulfate + 4-isopropylphenol <=> 4-isopropylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Danio rerio)


name: LTA4 is hydolysed to LTB4 by LTA4H (Bos taurus)


name: 5-hydroxypseudobaptigenin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => O2 + pratensein + reduced [NADPH--hemoprotein reductase]


name: C4b-binding protein binds C4b (Homo sapiens)


name: LYZ hydrolyzes peptidoglycans in the bacterial cell wall (Homo sapiens)


name: DEGS2 oxygenates dihydroceramide (Mus musculus)


name: tBID activates BAX protein (Mus musculus)


name: caffeine + H2O + ubiquinone-0 => 1,3,7-trimethylurate + ubiquinol-0


name: phosphinomethylisomalate => 2-(phosphinatomethylidene)butanedioate + H2O


name: Association of procollagen type XVIII (Mus musculus)


name: NADP(+) + octadecanoyl-CoA = (2E)-octadecenoyl-CoA + H(+) + NADPH


name: NADP(+) + sn-glycerol 3-phosphate => D-glyceraldehyde 3-phosphate + H(+) + NADPH


name: [aequorin] + 3 Ca(2+) = [aequorin]--dioxetanone


name: aminoacetaldehyde + H2O + 2 oxidized [4Fe-4S]-[ferredoxin] = glycine + 3 H(+) + 2 reduced [4Fe-4S]-[ferredoxin]


name: 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-tetradecanoyl-sn-glycero-3-phosphocholine


name: RBKS phosphorylates ribose to R5P (Mus musculus)


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Bos taurus)


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycerol <=> 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: PXLP-K754-GLDC dimer decarboxylates Gly (Sus scrofa)


name: OCT2 mediates tubular secretion of organic cations in the kidney (Canis familiaris)


name: 1-O-methyl-9-hydroperoxy-20-hydroxy-(5Z,7E,11Z,14Z)-eicosatetraenoate => 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] => 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-3-oxo-2,6-dimethyloct-6-enoyl-CoA + H(+) + NADH => (6E)-8-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-(3R)-hydroxy-2,6-dimethyloct-6-enoyl-CoA + NAD(+)


name: G alpha (q) in G (q):RGS complex is inactivated (Bos taurus)


name: a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1a + CMP + H(+)


name: Basigin interacts with CD43 (Homo sapiens)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Bos taurus)


name: RAC2 translocates to the ER membrane (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)


name: a 4-O-methyl-alpha-D-glucuronosyl ester derivative + H2O <=> 4-O-methyl-alpha-D-glucuronate derivative + an alcohol + H(+)


name: VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)


name: Galactosylation of collagen propeptide hydroxylysines by PLOD3 (Drosophila melanogaster)


name: dimethylallyl diphosphate + L-tryptophan <=> 4-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: TGFBR3 complex binds to TGFBR2 (Bos taurus)


name: dimethylallyl diphosphate + 3 isopentenyl diphosphate => 3 diphosphate + nerylneryl diphosphate


name: 3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine <=> 4',7,8-trihydroxy-3'-methoxyflavone-7-olate + H(+) + S-adenosyl-L-homocysteine


name: ent-kaur-16-ene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] => ent-kaur-16-en-19-ol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H2O + NAD(+) + propylamine <=> H(+) + NADH + NH4(+) + propanal


name: SOCS-1 and SOCS-3 binds to p-JAK2 (Danio rerio)


name: (2E)-geraniol + acetyl-CoA = (2E)-geranyl acetate + CoA


name: Recruitment of POLB to the AP site (Dictyostelium discoideum)


name: 1-(9Z-octadecenoyl)-3-hexadecanoylglycerol + CoA => (9Z)-octadecenoyl-CoA + 1-hexadecanoylglycerol


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Sus scrofa)


name: a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + a purine nucleobase


name: Ral-GDS binds to Ras-GTP (Rattus norvegicus)


name: cyclic tetraadenylate <=> 2 5'-hydroxy-diadenylate 2',3'-cylic phosphate


name: Activated ATM phosphorylates ABL1 (Sus scrofa)


name: 2 2-acetylphloroglucinol => 1,3,5-trihydroxybenzene + 2,4-diacetylphloroglucinol + H(+)


name: Activated FGFR2 phosphorylates PPTN11 (Drosophila melanogaster)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Plasmodium falciparum)


name: H(+) + H2O + hydroxyalbendazole + oxidized [NADPH--hemoprotein reductase] => albendazole + O2 + reduced [NADPH--hemoprotein reductase]


name: 6-amino-6-deoxyfutalosine + H2O => adenine + dehypoxanthine futalosine


name: 2 Na(+)(out) + taurocholate(out) <=> 2 Na(+)(in) + taurocholate(in)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Bos taurus)


name: H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-L-phenylalanine = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + L-phenylalanine


name: 2 5'-deoxyadenosine + A + 2 H(+) + 2 L-methionine + methylcyclopropylglycine-[protein] => AH2 + L-isoleucyl-[protein] + 2 S-adenosyl-L-methionine


name: [protein]-dithiol + NAD(+) <=> [protein]-disulfide + H(+) + NADH


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Canis familiaris)


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] = (11R)-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: a (2E,4Z)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(2E)-enoyl-CoA + NADP(+)


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl)-L-threonyl-[protein] + H(+) + UDP


name: ITCH polyubiquitinates TP73 (Mus musculus)


name: Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)


name: 26S proteasome degrades PolyUb-RUNX2 (Caenorhabditis elegans)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Canis familiaris)


name: (6Z)-octadecenamide + H2O <=> (6Z)-octadecenoate + NH4(+)


name: I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Mus musculus)


name: glycyl-L-aspartate(out) + 2 H(+)(out) => glycyl-L-aspartate(in) + 2 H(+)(in)


name: glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Xenopus tropicalis)


name: RND1 binds effectors (Xenopus tropicalis)


name: EML4 binds to microtubules (Xenopus tropicalis)


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Danio rerio)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Drosophila melanogaster)


name: (R)-2-hydroxyglutarate + pyruvate => (R)-lactate + 2-oxoglutarate


name: MAOA:FAD deaminates 3MT to HVA (Homo sapiens)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 (Caenorhabditis elegans)


name: CDK1 phosphorylates RUNX2 (Drosophila melanogaster)


name: STAT1,STAT3 binds PKR (Xenopus tropicalis)


name: ERBB2 KD mutants do not bind osimertinib (Homo sapiens)


name: 3-hydroxypyruvate + D-erythrose => (3S,4S,5R,6R)-3,4,5,6,7-pentahydroxy-2-oxoheptanoate


name: a ribonucleoside 5'-triphosphate + phytyl phosphate => a ribonucleoside 5'-diphosphate + phytyl diphosphate


name: luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] + UDP-alpha-D-glucuronate <=> H(+) + luteolin 7-O-[(beta-D-glucuronosyl)-(1->2)-(beta-D-glucuronide)] 4'-O-beta-D-glucuronide + UDP


name: Tachykinin receptor 1 (NK1) binds to substance P (Canis familiaris)


name: Phosphorylation of YAP by LATS1 (Bos taurus)


name: PKCdelta phosphorylates HuR (Rattus norvegicus)


name: beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + UDP-alpha-D-galactose <=> a neolactoside nLc4Cer + H(+) + UDP


name: EOMES and TBXT bind the POU5F1 (OCT4) gene (Homo sapiens)


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Sus scrofa)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Caenorhabditis elegans)


name: 24-methylenelophenol methyl oxidase activity


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-(9Z-octadecenoyl)-glycerol + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2-(9Z-octadecenoyl)-glycerol


name: The G alpha-olf:GDP:Adenylate cyclase complex dissociates (Danio rerio)


name: botB HC:LC binds SYT1 or 2 and GT1b on the target cell surface (Homo sapiens)


name: Cytoslic carboxylases translocate to mitochondrial matrix (Drosophila melanogaster)


name: MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Gallus gallus)


name: 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O = ADP-D-ribose + H(+) + L-glutamyl-[protein]


name: glycyl-L-leucine(out) + 2 H(+)(out) = glycyl-L-leucine + 2 H(+)(in)


name: 3 O2 + 3 reduced [NADPH--hemoprotein reductase] + silphinene => 4 H(+) + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase] + silphinene-15-oate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = (9Z)-octadecenoate + H(+) + sn-glycero-3-phospho-(1'-sn-glycerol)


name: a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] => a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H2O => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + D-galactose


name: UDP-N-acetyl-alpha-D-glucosamine(in) + UMP(out) <=> UDP-N-acetyl-alpha-D-glucosamine(out) + UMP(in)


name: QPRT transfers PRIB to QUIN to form NAMN (Sus scrofa)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine


name: L-leucine(in) + L-lysine(out) + Na(+)(in) => L-leucine(out) + L-lysine(in) + Na(+)(out)


name: 1-propanol + acetyl-CoA = CoA + propyl acetate


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Mus musculus)


name: trichloroethene reductive dehalogenase activity


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Canis familiaris)


name: H2O + nitrous oxide => 2 e(-) + 2 H(+) + 2 nitric oxide


name: carbofuran + H(+) + H2O => 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol + CO2 + methylamine


name: guanosine(2922) in 27S pre-rRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(2922) in 27S pre-rRNA + H(+) + S-adenosyl-L-homocysteine


name: cholate + lithocholoyl-CoA <=> choloyl-CoA + lithocholate


name: n AMP + n diphosphate + n H(+) + N(5)-(L-ornithyl)-[N(5)-(L-ornithyl)]n-1 => n ATP + H2O + n L-ornithine


name: Prolysyl oxidase activation (Homo sapiens)


name: CYB5A:heme reduces Asc.- to AscH- (Bos taurus)


name: Endocytosis of Ca impermeable AMPA receptors (Rattus norvegicus)


name: testosterone dehydrogenase (NAD+) activity


name: beta-alanyl-dopamine + H2O <=> beta-alanine + dopamine


name: RBP4 binds atROL (Caenorhabditis elegans)


name: 6alpha-hydroxy-28-norteasterone + O2 + reduced [NADPH--hemoprotein reductase] = 28-norteasterone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: FLT3LG dimer:FLT3 dimer autophosphorylates (Homo sapiens)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Gallus gallus)


name: L-alanine + taurocholate => L-alanocholate + taurine


name: [(1->4)-beta-D-glucosyl](n) + phosphate <=> [(1->4)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Bos taurus)


name: MBTPS1 (S1P) cleaves ATF6 (ATF6-alpha) (Sus scrofa)


name: ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Mus musculus)


name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter (Homo sapiens)


name: DCC interaction with SIAH2 (Danio rerio)


name: 3,5-dimethylbenzyl alcohol + O2 => 3,5-dimethylbenzaldehyde + H2O2


name: Gbeta:gamma activation of PLC beta (Homo sapiens)


name: RHOBTB2 binds interacting proteins at the endosome membrane (Dictyostelium discoideum)


name: Hemes bind to CLEC1B dimer (Homo sapiens)


name: a ganglioside Ac-O-8-GD2(d18:1(4E)) <=> a ganglioside Ac-O-9-GD2(d18:1(4E))


name: Initial resection of double-strand break ends (Sus scrofa)


name: 3-hydroxyhexadecanoate + O2 + reduced [NADPH--hemoprotein reductase] = 3,16-dihydroxyhexadecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: H2O + L-alanyl-L-aspartate <=> L-alanine + L-aspartate


name: a cytidine(6-4)thymidine in DNA => a cytidine-thymine dinucleotide in DNA


name: N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N,N-dimethyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: [protein]-peptidylproline (omega=0) => [protein]-peptidylproline (omega=180)


name: Estrogen-responsive MYB gene expression (Homo sapiens)


name: 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + H(+) + NADPH => 4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NADP(+)


name: Phosphorylated SHC1 recruits SHIP (Bos taurus)


name: SIRT3 deacetylates AcK-IDH2 dimer (Sus scrofa)


name: CYB5Rs reduce MetHb to HbA (Rattus norvegicus)


name: 7alpha-hydroxycholest-4-en-3-one + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: apigenin + S-adenosyl-L-methionine => genkwanin + H(+) + S-adenosyl-L-homocysteine


name: L-pipecolate + NAD(+) = Delta(1)-piperideine-2-carboxylate + H(+) + NADH


name: SAMD8 transfers phosphatidyl from PE onto C16DH CER (Mus musculus)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Plasmodium falciparum)


name: O-acetyl-L-serine + uracil => 3-(uracil-1-yl)-L-alanine + acetate + H(+)


name: Release of 40S and 60S subunits from the 80S ribosome  (Homo sapiens)


name: PSMG3:PSMG4 dimer binds PSMA5 (Xenopus tropicalis)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Sus scrofa)


name: a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA = an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + holo-[ACP]


name: RGGT geranylgeranylates RAB proteins (Plasmodium falciparum)


name: H2O2 + NAD(+) => 1,6-dihydro-beta-NAD + H(+) + O2


name: 5,6,7,8-tetrahydropteridine + NADP(+) = 6,7-dihydropteridine + H(+) + NADPH


name: N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity


name: 2-oxoglutarate + chloride + H(+) + L-threonyl-[peptidyl-carrier protein] + O2 <=> 4-chloro-L-threonyl-[peptidyl-carrier protein] + CO2 + H2O + succinate


name: a 3-oxo-ultra-long-chain mono-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP] => an ultra-long-chain mono-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP]


name: S-adenosyl-L-methionine + serotonin = 5-methoxytryptamine + H(+) + S-adenosyl-L-homocysteine


name: Aquaporins passively transport water out of cells (Homo sapiens)


name: PEX19:class I PMP binds PEX3 (Dictyostelium discoideum)


name: a pyrimidine ribonucleoside 5'-phosphate + H2O <=> a pyrimidine nucleobase + D-ribose 5-phosphate


name: NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Rattus norvegicus)


name: a very-long-chain 2,3-saturated fatty acyl-CoA + NADP(+) <=> a very-long-chain (2E)-enoyl-CoA + H(+) + NADPH


name: p-STAT1dimer:KPNA1 binds KPNB1 (Xenopus tropicalis)


name: POU5F1 (OCT4), SOX2, NANOG bind the FGF2 promoter (Homo sapiens)


name: EGFR phosphorylates EPS15 (Drosophila melanogaster)


name: H(+) + NADPH + yaequinolone D => H2O + NADP(+) + penigequinolone A


name: Relaxin 3 receptor 1 binds relaxin 3 (Mus musculus)


name: 2 H(+) + H2O2 + 2 iodide = diiodine + 2 H2O


name: crosslinked fibrin multimer + tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) (Bos taurus)


name: NLRC5 binds to CARD domain of Mda5 and prevents IPS1 binding (Gallus gallus)


name: ESTG binds ESR1:chaperone complex (Xenopus tropicalis)


name: 2'-deoxyadenosine + phosphate <=> 2-deoxy-alpha-D-ribose 1-phosphate + adenine


name: Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription (Homo sapiens)


name: aclacinomycin T + H2O => 15-demethylaclacinomycin T + methanol


name: CoA + H(+) + N-acetyl-D-glutamine => acetyl-CoA + D-glutamine


name: ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Bos taurus)


name: (3R)-hydroxybutanoyl-[ACP] => (2E)-butenoyl-[ACP] + H2O


name: dimethylallyl diphosphate + H(+) + hapalindole U <=> ambiguine H + diphosphate


name: Caspase 3-mediated cleavage of DFF45 (117) (Sus scrofa)


name: 2-hydroxydodecanoate + O2 => 2-oxododecanoate + H2O2


name: Separation of elongating transcript from template (Homo sapiens)


name: a 5'-end diphospho-(purine-ribonucleoside) in mRNA + H(+) + N(tele)-(N(7)-methylguanosine 5'-phospho)-L-histidyl-[protein] = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-histidyl-[protein]


name: Expression of FATP1 (SLC27A1) (Homo sapiens)


name: SLC7A10-mediated uptake of small neutral amino acids (Mus musculus)


name: H(+) + menadione + NADPH <=> menadiol + NADP(+)


name: (2R,3R,5S)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + AH2 + 2 S-adenosyl-L-methionine => (2R,3R,5S,6R)-6-(methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + 5'-deoxyadenosine + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine


name: hydroquinone + UDP-alpha-D-glucose => H(+) + hydroquinone O-beta-D-glucopyranoside + UDP


name: guanosine 3',5'-bis(diphosphate) + H(+) + phosphate => guanosine 3'-diphosphate 5'-triphosphate + H2O


name: a 3-hydroxy-fatty acyl-CoA => a (2E)-enoyl-CoA + H2O


name: Formation of DHA-CoA catalysed by sterol carrier protein X (SCPx) (Canis familiaris)


name: Loading of PCNA - Sliding Clamp Formation (Caenorhabditis elegans)


name: AVP(20-28) binds AVPR1A,B (Mus musculus)


name: a 2-acyl-sn-glycerol 3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ATP <=> [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + ADP


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Sus scrofa)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Canis familiaris)


name: H2O + sphing-4-enine-phosphocholine = H(+) + phosphocholine + sphing-4-enine


name: Association of procollagen type XVII (Gallus gallus)


name: 10-deoxymethynolide + dTDP-alpha-D-desosamine <=> 10-deoxymethymycin + dTDP + H(+)


name: 27-hydroxywithanone + UDP-alpha-D-glucose <=> H(+) + UDP + withanone 27-O-beta-D-glucoside


name: 5-guanidino-2-oxopentanoate + H2O2 + NH4(+) => H2O + L-arginine + O2


name: 3',5'-cyclic AMP(in) => 3',5'-cyclic AMP(out)


name: ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Homo sapiens)


name: 3-dehydro-4-O-phospho-L-erythronate + H(+) => CO2 + dihydroxyacetone phosphate


name: AP-1 transcription factor binds IGFBP7 promoter (Homo sapiens)


name: D-erythrose 4-phosphate + H2O + phosphoenolpyruvate <=> 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate


name: (2E,6E)-farnesyl diphosphate = (+)-thujopsene + diphosphate


name: Rev multimer-bound HIV mRNA associates with Crm1 (Homo sapiens)


name: cadaverine(out) + H(+)(out) => cadaverine(in) + H(+)(in)


name: a 2'-deoxyribonucleoside 5'-triphosphate + 2 H2O <=> a 2'-deoxyribonucleoside 5'-phosphate + 2 H(+) + 2 phosphate


name: apo-[aequorin] + 3 Ca(2+) + coelenterazine + O2 => [excited state blue fluorescent protein] + CO2


name: Vamp2 associated secretory vesicle to plasma membrane transport (Caenorhabditis elegans)


name: PEX7 binds cargo proteins containing PTS2 (Canis familiaris)


name: anthranilate + S-adenosyl-L-methionine => H(+) + N-methylanthranilate + S-adenosyl-L-homocysteine


name: p100:RELB binds active NIK:p-IKKA dimer (Canis familiaris)


name: 3-O-(beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose <=> 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP


name: N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity


name: LRAT esterifies RBP1:atROL and FACYLs to atREs (Homo sapiens)


name: 7-oxolithocholate + H(+) + NADPH = NADP(+) + ursodeoxycholate


name: CP110 and CEP97 dissociate from the centriole (Canis familiaris)


name: BST1 hydrolyzes NAD+ to yield NAM and ADP-ribose (Homo sapiens)


name: FMO1:FAD N-oxidises TAM (Dictyostelium discoideum)


name: 2-oxoglutarate(out) + heptanedioate(in) <=> 2-oxoglutarate(in) + heptanedioate(out)


name: N-acetylglucosaminyl-PI + H2O -> glucosaminyl-PI + acetate (Bos taurus)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-purine ribonucleoside in mRNA + H2O = a 5'-end phospho (purine-ribonucleoside) in mRNA + 2 H(+) + N(2),N(2),N(7)-trimethyl-GDP


name: acetyl-CoA + L-2,4-diaminobutanoate = (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: aklavinone + NADP(+) = aklaviketone + 2 H(+) + NADPH


name: GMP + NAD(+) => H(+) + N(2)-(ADP-D-ribosyl)-GMP + nicotinamide


name: silicon efflux transmembrane transporter activity


name: 2-aminophenoxazin-3-one + AH2 + 2 H2O => 2 2-aminophenol + A + O2


name: ATR activation at DNA DSBs (Canis familiaris)


name: SLC22A1 transports Cipro into hepatic cell (Danio rerio)


name: Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Drosophila melanogaster)


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Gallus gallus)


name: chloride(in) + sulfate(out) = chloride(out) + sulfate(in)


name: dihydroxyacetone phosphate + ubiquinol-8 => sn-glycerol 3-phosphate + ubiquinone-8


name: NMRK2 phosphorylates NR to yield NMN (Drosophila melanogaster)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Xenopus tropicalis)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Saccharomyces cerevisiae)


name: a ribonucleoside 5'-diphosphate + GTP = a ribonucleoside 5'-triphosphate + GDP


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O => 1D-myo-inositol hexakisphosphate + H(+) + phosphate


name: 5alpha-androstan-1,3,17-trione + AH2 => 1-hydroxy-5alpha-androstan-3,17-dione + A


name: GYS1 catalyzes the incorporation of phosphoglucose into glycogen-GYG1 (Danio rerio)


name: Internalisation of the insulin receptor (Mus musculus)


name: SREBP1A,1C binds the GPAM promoter (Homo sapiens)


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Homo sapiens)


name: dopamine + 2 L-ascorbate + O2 <=> (R)-noradrenaline + H2O + 2 monodehydro-L-ascorbate radical


name: L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH


name: 1,4-benzoquinone + H(+) + NADPH <=> hydroquinone + NADP(+)


name: 2-oxoglutarate + a (2R,3S,4S)-leucoanthocyanidin + O2 = a (4S)-2,3-dehydroflavan-3,4-diol + CO2 + H(+) + H2O + succinate


name: 2-oxospirilloxanthin + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] => 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] + spirilloxanthin


name: 2-oxoglutarate + [ribosomal protein S23]-L-proline + O2 <=> [ribosomal protein S23]-trans-3-hydroxy-L-proline + CO2 + succinate


name: calcium-dependent phospholipase C activity


name: PIAS3 SUMOylates RELA with SUMO3 (Gallus gallus)


name: 2-hydroxyeicosanoyl-CoA + CO2 + succinate => 2-oxoglutarate + eicosanoyl-CoA + O2


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)


name: Kinesin-5 is a homotetramer (Saccharomyces cerevisiae)


name: Activation of MMP9 intermediate form by MMPs (Gallus gallus)


name: PSGs bind proteoglycans and TGF-beta1 (Rattus norvegicus)


name: 3-oxodecanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxydecanoyl-[ACP] + NADP(+)


name: KSRP recruits RNA degradation activities (Rattus norvegicus)


name: ATAC spliceosome mediated Lariat formation,5' splice site cleavage (Drosophila melanogaster)


name: agmatine + H2O = N-carbamoylputrescine + NH4(+)


name: DCAKD phosphorylates DP-CoA (Mus musculus)


name: PKC autophosphorylates (Caenorhabditis elegans)


name: Maturation of the 20S thymoproteasome core particle (Homo sapiens)


name: RORA, EP300, PPARGC1A bind NR1D1 gene (Homo sapiens)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Homo sapiens)


name: H2O + N,N-dihydroxy-L-aspartate + NADP(+) => H(+) + N-hydroxy-L-aspartate + NADPH + O2


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Dictyostelium discoideum)


name: phenylsuccinate + succinyl-CoA = 3-phenylsuccinyl-CoA + succinate


name: 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+) => 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF3A (Gallus gallus)


name: Formation of p-STAT1 homodimer (Canis familiaris)


name: RHOD binds effectors at the endosome membrane (Homo sapiens)


name: GTP + pyruvate <=> GDP + H(+) + phosphoenolpyruvate


name: 4-methylsulfanyl-2-oxobutanoate + H(+) => 3-methylsulfanylpropanal + CO2


name: dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA (Rattus norvegicus)


name: 2-hydroxyethylphosphonate + CTP => cytidine 5'-{[hydroxy(2-hydroxyethyl)phosphonoyl]phosphate} + diphosphate


name: 3beta-hydroxyandrost-5-en-17-one + H(+) + NADPH => androst-5-en-3beta,17beta-diol + NADP(+)


name: oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor


name: (3R)-citramalyl-CoA => acetyl-CoA + pyruvate


name: hexadecanoyl-[ACP] + NAD(+) => (2E)-hexadecenoyl-[ACP] + H(+) + NADH


name: TAG is hydrolyzed to DAG by PNPLA2/3 (Danio rerio)


name: RGGT geranylgeranylates RAB proteins (Saccharomyces cerevisiae)


name: 3beta-hydroxyandrost-5-en-17-one + UDP-alpha-D-glucose = dehydroepiandrosterone 3-beta-D-glucoside + H(+) + UDP


name: NADP(+) + pentan-3-one = H(+) + NADPH + pent-1-en-3-one


name: 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate => 2,3-di-(10Z-heptadecenoyl)-sn-glycerol + 9-(10Z-heptadecenoyloxy)-octadecanoate


name: a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate <=> an alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: p-S MAPKAPK5 phosphorylates HSPB1 (Mus musculus)


name: L-alanine transmembrane transporter activity


name: dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine <=> dTDP-alpha-D-forosamine + H(+) + S-adenosyl-L-homocysteine


name: Retromer associates with WLS (Mus musculus)


name: RNF41 binds neuregulin-activated ERBB3 (Sus scrofa)


name: Keratin type I/type II heterodimers form tetramers (Sus scrofa)


name: GLI3R translocates to the nucleus (Canis familiaris)


name: Activated ERBB2 binds PTK6 (BRK) (Rattus norvegicus)


name: 2-oxoglutarate + H(+) + O2 + trihazone A => 2 CO2 + H2O + succinate + trihazone D


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + L-phenylalanine => H2O + N-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-L-phenylalanine


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate => alpha-selinene + diphosphate


name: 2-oxoglutarate + L-prolyl-[collagen] + O2 => CO2 + succinate + trans-3-hydroxy-L-prolyl-[collagen]


name: MBTPS1 (S1P) cleaves ATF6B (ATF6-beta) (Bos taurus)


name: LC3 is cleaved by ATG4 (Caenorhabditis elegans)


name: H2O + luteolin 4'-O-beta-D-glucoside <=> beta-D-glucose + luteolin


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Caenorhabditis elegans)


name: ATP + D-arabinose = ADP + D-arabinose 5-phosphate + H(+)


name: 2-oxoheptanedioate + acetyl-CoA + H2O => (R)-trihomocitrate + CoA + H(+)


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Sus scrofa)


name: H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine => (R)-4'-phosphopantetheine + CO2


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-octadecanoyl-sn-glycero-3-phosphocholine


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Sus scrofa)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Homo sapiens)


name: APC/C:Cdh1-mediated degradation of Skp2 (Gallus gallus)


name: PSAP(195-273) forms a dimer (Sus scrofa)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Mus musculus)


name: (R)-3-hydroxybutanoate(in) + 2 Na(+)(in) => (R)-3-hydroxybutanoate(out) + 2 Na(+)(out)


name: CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Sus scrofa)


name: SLC17A6,7,8 exchange cytosolic L-Glu for synaptic vesicle H+ (Homo sapiens)


name: KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Bos taurus)


name: ADP + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] <=> AMP + H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase]


name: RAC3 GEFs activate RAC3 (Canis familiaris)


name: citrate(out) + H(+)(out) => citrate(in) + H(+)(in)


name: 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O <=> 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + 2 H(+) + phosphate


name: Peroxisomal uptake of very long-chain fatty acyl CoA (Saccharomyces cerevisiae)


name: Trace amine-associated receptors can bind trace amines (Bos taurus)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Xenopus tropicalis)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Homo sapiens)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA) (Mus musculus)


name: D-galactonate + H(+) => D-galactono-1,4-lactone + H2O


name: Autoproteolytic cleavage of Hh precursors (Rattus norvegicus)


name: NEU1 hydrolyses Neu5Ac from glycoconjugates (Canis familiaris)


name: 5,6-dihydrouracil + NADP(+) => H(+) + NADPH + uracil


name: 8-oxo-dGTP + 2 H2O = 8-oxo-dGMP + 2 H(+) + 2 phosphate


name: 2 cob(II)inamide-[corrinoid adenosyltransferase] + reduced [electron-transfer flavoprotein] = 2 cob(I)inamide-[corrinoid adenosyltransferase] + 3 H(+) + oxidized [electron-transfer flavoprotein]


name: ASAP1 stimulates GTPase activity of ARF4 (Danio rerio)


name: [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate => [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose <=> a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H(+) + UDP


name: GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine (Rattus norvegicus)


name: aldehyde dehydrogenase (NAD+) inhibitor activity


name: Association of procollagen type II (Caenorhabditis elegans)


name: a 1-O-alkyl-2-acetyl-sn-glycerol + CDP-choline = a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: NADP(+) + propane-1,2-diol => (S)-lactaldehyde + H(+) + NADPH


name: dimethylallyl diphosphate + isopentenyl diphosphate = (2E)-geranyl diphosphate + diphosphate


name: (-)-pluviatolide + S-adenosyl-L-methionine => (-)-bursehernin + H(+) + S-adenosyl-L-homocysteine


name: H2O + orobanchol <=> 5-hydroxy-3-methylfuran-2(5H)-one + orobanchol ABC-rings


name: (+)-isomalbrancheamide B + FADH2 => (+)-premalbrancheamide + chloride + FAD + 2 H(+)


name: Activated thrombin (factor IIa) cleaves PAR3,4, activating them (Mus musculus)


name: (5R)-5-hydroxy-L-lysyl-[collagen] + hypobromite + L-methionyl-[collagen] <=> [collagen]-(5R)-5-hydroxy-L-lysyl-N-S-L-methionyl-[collagen] + bromide + H(+) + H2O


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Drosophila melanogaster)


name: G6PC hydrolyzes G6P to Glc and Pi (liver) (Rattus norvegicus)


name: (5S)-hydroxy-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase] = (5S,18)-dihydroxy-(6E,8Z)-octadecadienoate + H(+) + H2O + oxidized [NADH--hemoprotein reductase]


name: RAC2 binds effectors at the mitochondrial outer membrane (Dictyostelium discoideum)


name: L-threonyl-[myosin light chain] + phosphate => H2O + O-phospho-L-threonyl-[myosin light chain]


name: a 5,6-dihydrouridine in tRNA + NADP(+) => a uridine in tRNA + H(+) + NADPH


name: UBQLNs bind UIM-containing adaptor proteins (Drosophila melanogaster)


name: a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O <=> a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + sulfate


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Dictyostelium discoideum)


name: IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Gallus gallus)


name: p-S216-CDC25C translocates to the cytosol (Schizosaccharomyces pombe)


name: acetate + eugenol + NADP(+) <=> (E)-coniferyl acetate + NADPH


name: UROD decarboxylates URO3 to COPRO3 (Danio rerio)


name: O2 + reduced [NADPH--hemoprotein reductase] + tetradecanoate = 11-hydroxytetradecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: epoxypheophorbide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] => 3 H(+) + O2 + pheophorbide a + 2 reduced [2Fe-2S]-[ferredoxin]


name: ERBB2 ECD mutants bind trastuzumab (Homo sapiens)


name: H(+)(in) + sucrose(out) <=> H(+)(out) + sucrose(in)


name: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH


name: PI3-kinase binds to the active receptor (Drosophila melanogaster)


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Sus scrofa)


name: CERK phosphorylates CERA to form C1P (Sus scrofa)


name: Bile salts and acids dissociate from ALB (Sus scrofa)


name: Protein Kinase B (AKT) phosphorylates KSRP (Drosophila melanogaster)


name: Arachidonate is converted to HXA3/B3 by ALOX12 (Mus musculus)


name: 2 Na(+)(out) + taurochenodeoxycholate(out) => 2 Na(+)(in) + taurochenodeoxycholate(in)


name: Formation of the cap-binding eIF4F complex (Canis familiaris)


name: aclacinomycin N + O2 = aclacinomycin A + H2O2


name: The distal appendage proteins recruit TTBK2 (Homo sapiens)


name: site-specific endodeoxyribonuclease activity, specific for altered base


name: "Site-specific endodeoxyribonucleases specific for altered bases"


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Drosophila melanogaster)


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-phosphate + a 3'-end 2'-deoxyribonucleotide-DNA + H(+) => a 3'-end 2'-deoxyribonucleotidyl-deoxyribonucleotide-DNA + H2O


name: 3-methyl-1,2-didehydro-2,3-dihydrosqualene + H(+) + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + squalene


name: The receptor:G-protein complex  binds GTP (Drosophila melanogaster)


name: all-trans-retinal + H2O + O2 = all-trans-retinoate + H(+) + H2O2


name: Activated HOP is autophosphorylated and/or transphosphorylated (Drosophila melanogaster)


name: TAT deaminates tyrosine (Caenorhabditis elegans)


name: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate


name: L-pipecolate + NADP(+) => Delta(1)-piperideine-2-carboxylate + H(+) + NADPH


name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol (Mus musculus)


name: 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine


name: 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: (+)-premalbrancheamide + bromide + FAD + 2 H(+) => (+)-isomalbrancheamide C + FADH2


name: ITGA2B gene transcription is stimulated by the complex of RUNX1, GATA1 and PRMT1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)


name: alpha-D-mannopyranose + beta-D-mannopyranosyl-(1->2)-D-mannopyranose => beta-D-Manp-(1->2)-beta-D-Manp-(1->2)-D-Manp + H2O


name: H2O + N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + NAD(+) => N(delta)-hydroxy-N(omega)-methyl-L-arginine + NADH + O2


name: 2 all-trans-retinal => all-trans-beta-carotene + O2


name: L1 trans-homophilic interaction (Xenopus tropicalis)


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Canis familiaris)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Canis familiaris)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Danio rerio)


name: RNF144A polyubiquitinates PRKDC (Dictyostelium discoideum)


name: AH2 + NH4(+) + sulfoacetaldehyde => A + H2O + taurine


name: a globoside NORint + UDP-alpha-D-galactose <=> a globoside NOR2 + H(+) + UDP


name: PTPN13:PLEKHA1,2 bind PI(3,4)P2 (Homo sapiens)


name: ITPA hydrolyses XTP to XMP (Schizosaccharomyces pombe)


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-glycerol <=> 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n CMP + n H(+)


name: Production of AA by iPLA2 upon FCGR activation (Xenopus tropicalis)


name: 2 (S)-lactate(in) + thromboxane B2(out) <=> 2 (S)-lactate(out) + thromboxane B2(in)


name: transmembrane receptor histidine kinase activity


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 = N-(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl-gamma-aminobutanoate


name: CO2 + gibberellin A19 + H2O + succinate => 2-oxoglutarate + gibberellin A44 + O2


name: Activated FGFR3:p-SHC1 binds GRB2:SOS1 (Mus musculus)


name: 2-acyl LPE is acylated to PE by LPEAT (Saccharomyces cerevisiae)


name: histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen (Rattus norvegicus)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Caenorhabditis elegans)


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Gallus gallus)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Xenopus tropicalis)


name: Phosphorylation and activation of VAV2/VAV3 by SYK (Rattus norvegicus)


name: 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + H(+) + S-adenosyl-L-homocysteine


name: KRAB-ZFP binds retroelement DNA in chromatin (Caenorhabditis elegans)


name: TFIIH binds GG-NER site to form a verification complex (Dictyostelium discoideum)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Gallus gallus)


name: NSF ATPase activity dissociates cis-SNARE (Gallus gallus)


name: Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Rattus norvegicus)


name: acetate + ATP + cytidine(34) in elongator tRNA(Met) <=> AMP + diphosphate + N(4)-acetylcytidine(34) in elongator tRNA(Met)


name: 4-hydroxy-L-proline(out) + Na(+)(out) => 4-hydroxy-L-proline(in) + Na(+)(in)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Canis familiaris)


name: (E)-4-coumaroyl-CoA + H(+) + NADPH => (E)-4-coumaraldehyde + CoA + NADP(+)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Caenorhabditis elegans)


name: SLC6A6-mediated uptake of taurine and beta-alanine (Gallus gallus)


name: a Delta(7)-sterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a Delta(5),Delta(7)-sterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: p-Y701-STAT1:p-Y705-STAT3 translocates from the cytosol to the nucleus (Gallus gallus)


name: SLC51A:SLC51B transports bile salts from cytosol to extracellular region (Bos taurus)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Sus scrofa)


name: ATP + hydrogencarbonate + propanoyl-CoA = ADP + H(+) + methylmalonyl-CoA + phosphate


name: HHAT palmitoylates Hh N-terminal fragment (Rattus norvegicus)


name: C-ter TLR7 dimer binds imiquimod (Gallus gallus)


name: OTUD7A hydrolyses K11diUb (Xenopus tropicalis)


name: POU5F1 (OCT4), SOX2, NANOG bind the SOX2 promoter (Homo sapiens)


name: 2-oxoglutarate + 3-(N-acetyl-N-hydroxy)aminopropylphosphonate + O2 => (R)-(3-(acetylhydroxyamino)-2-hydroxypropyl)phosphonate + CO2 + succinate


name: 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose = (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + H(+) + UDP


name: Formation of the SET1B complex (Gallus gallus)


name: 5,10-methyleneTHF polyglutamate + glycine <=> tetrahydrofolate polyglutamate (THF polyglutamate) + serine (Danio rerio)


name: HIPK2 phosphorylates MECP2 (Canis familiaris)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Plasmodium falciparum)


name: FOXO:SMAD complex binds CDKN1A gene promoter (Homo sapiens)


name: Ligand-independent dimerization of KIT juxtamembrane domain mutants (Homo sapiens)


name: ADP + an N(4)-acetylcytidine in tRNA + CoA + H(+) + phosphate => a cytidine in tRNA + acetyl-CoA + ATP + H2O


name: Elastic fibres bind associated proteins (Homo sapiens)


name: glandicoline B + S-adenosyl-L-methionine <=> H(+) + meleagrin + S-adenosyl-L-homocysteine


name: 7,8-dihydromethanopterin + H(+) + NADPH => 5,6,7,8-tetrahydromethanopterin + NADP(+)


name: ACY1:Zn2+ dimer deacetylates NAC to L-Cys (Canis familiaris)


name: Active FLT3 binds to SLA2 (Canis familiaris)


name: H2O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine => 3 H(+) + 2 NADH + UDP-N-2-acetamido-2-deoxy-alpha-D-glucuronate


name: NOX3 complex:RAC1:GTP generates superoxide from oxygen (Xenopus tropicalis)


name: H2O + L-seryl-tRNA(Lys) = L-serine + tRNA(Lys)


name: (4Z)-2-oxohept-4-enedioate + H2O => (4S)-4-hydroxy-2-oxoheptanedioate


name: AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)


name: SULTs transfer (SO4)2- group to PREG (Homo sapiens)


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Mus musculus)


name: 3'-phosphoadenylyl sulfate + beta-D-galactosyl-(1<->1)-sphing-4-enine <=> 6-O-sulfo-beta-D-galactosyl-(1<->1)-sphing-4-enine + adenosine 3',5'-bisphosphate + H(+)


name: cordycepin + H(+) + H2O => 3'-deoxyinosine + NH4(+)


name: SARS-CoV-2 nsp16 binds to U2 snRNA (Homo sapiens)


name: RCHY1 monoubiquitinates POLH (Xenopus tropicalis)


name: CoA + S-(9Z-octadecenoyl)-L-cysteinyl-[protein] => (9Z)-octadecenoyl-CoA + L-cysteinyl-[protein]


name: mesaconate + succinyl-CoA => 2-methylfumaryl-CoA + succinate


name: phenylcoumaran benzylic ether reductase activity


name: HRSP12 deaminates 2AA to 2OBUTA (Saccharomyces cerevisiae)


name: Transfer of NEDD8 to AcM-UBE2M (Canis familiaris)


name: ANO1 inhibitors bind ANO1 (Homo sapiens)


name: Formation of hair keratin fibres (Bos taurus)


name: NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP (Canis familiaris)


name: 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-nonadecanoyl-sn-glycero-3-phosphocholine => 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-octadecanoyl-sn-glycero-3-phosphocholine