name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Mus musculus)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + (E)-4-coumaroyl-CoA => (E)-4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA


name: (S)-malate + a menaquinone => a menaquinol + oxaloacetate


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Schizosaccharomyces pombe)


name: oxidative phosphorylation uncoupler activity


name: SLC16A1:BSG cotransports monocarboxylates, H+ from extracellular region to cytosol (Homo sapiens)


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Bos taurus)


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Schizosaccharomyces pombe)


name: Recruitment of SYK to p-DAP12 (Homo sapiens)


name: p-S54,92,203-BRF1 binds 14-3-3 (Danio rerio)


name: (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H(+) + NADPH => (19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+)


name: H2O2 + L-lysyl-[collagen] + L-methionyl-[collagen] <=> [collagen]-L-lysyl-N-S-L-methionyl-[collagen] + H(+) + 2 H2O


name: MCM4, MCM6 and MCM7 form a heterotrimer (Plasmodium falciparum)


name: Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA (Sus scrofa)


name: H2O + N-acetyl-beta-D-galactosaminyl-(1->4)-beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide = a beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide + N-acetyl-beta-D-galactosamine


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Homo sapiens)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Rattus norvegicus)


name: Phosphorylation of L1 by ERK (Caenorhabditis elegans)


name: an N-acyl-sphinga-4E,14Z-dienine + CoA + H(+) => a fatty acyl-CoA + sphinga-4E,14Z-dienine


name: A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2


name: STAMBP binds STAM (Drosophila melanogaster)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Drosophila melanogaster)


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Danio rerio)


name: PLCG1 disassociates from VEGFR2 and translocate to PM (Danio rerio)


name: Interaction of PECAM-1 and SHP-2 (Rattus norvegicus)


name: EGFR phosphorylates GPNMB (Xenopus tropicalis)


name: EHHADH dehydrogenates 3-hydroxyhexacosanoyl-CoA (Sus scrofa)


name: a dicarboxylate(in) + N-benzoylglycine(out) = a dicarboxylate(out) + N-benzoylglycine(in)


name: 2xPDXK:2xZn2+ phosphorylates PXL (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-acyl-sn-glycero-3-phosphate => a 1,2-diacyl-sn-glycero-3-phosphate + a 1-acyl-sn-glycero-3-phosphocholine


name: (S)-8-oxocitronellyl enol + NAD(+) <=> (6E)-8-oxogeranial + H(+) + NADH


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Mus musculus)


name: 4-methylphenol + H2O + NAD(+) => H(+) + NADH + O2 + toluene


name: ergosta-5,7-dien-3betabeta-ol + H(+) + NADPH + O2 <=> ergosterol + 2 H2O + NADP(+)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + UDP


name: S-adenosyl-L-methionine + theobromine => caffeine + H(+) + S-adenosyl-L-homocysteine


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Bos taurus)


name: ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate


name: 1-O-methyl-12-hydroperoxy-20-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate => 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: LIPC dimer hydrolyses TAG to DAG and FA (Homo sapiens)


name: HHAT palmitoylates Hh N-terminal fragment (Gallus gallus)


name: A + dihydropyriculariol => AH2 + pyriculariol


name: (2E,6E)-farnesyl diphosphate <=> diphosphate + pentalenene


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b (d18:1(4E)) + CMP + H(+)


name: Shikimate results from hydration of DHS (Mycobacterium tuberculosis)


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Homo sapiens)


name: EVL:PPL heterodimer binds the inner surface of the plasma membrane (Mus musculus)


name: a (2R)-2-hydroxycarboxylate + a halide anion + H(+) => an (R)-2-haloacid + H2O


name: H2O + N-formylmaleamate <=> formate + H(+) + maleamate


name: H(+) + L-histidinal + NADH => L-histidinol + NAD(+)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Mus musculus)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  (Homo sapiens)


name: an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> (5Z,8Z,11Z,14Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Dissociation of the COP1-p53 complex (Homo sapiens)


name: glycine + hexacosanoate => H2O + N-hexacosanoylglycine


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 11-hydroxy-(9Z,12Z)-octadecadienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CCNK binds CDK12 (Saccharomyces cerevisiae)


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z)-octadecenoyl-2-hexadecanoylglycerol => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 2-hexadecanoylglycerol


name: (2E,10E)-dode-2,10-dicenoyl-CoA + H2O + oxaloacetate => (4E,11E)-2-hydroxytrideca-4,11-dien-1,2,3-tricarboxylate + CoA + H(+)


name: 1-acyl LPC is acylated to PC by LPCAT (Bos taurus)


name: ALK binds ligand midkine (MDK) (Mus musculus)


name: RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate = delta-guaiene + diphosphate


name: P2Y purinoceptor 1 activates MAP kinase p38 alpha (Xenopus tropicalis)


name: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH


name: PDPK1 binds PIP3 (Dictyostelium discoideum)


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Plasmodium falciparum)


name: Defective POMT1 does not transfer Man from Dol-P-Man to DAG1 (Homo sapiens)


name: 2 H(+) + L-aspartate + NADH => H2O + L-aspartate 4-semialdehyde + NAD(+)


name: KDM2A, KDM2B, KDM4A demethylate MeK37-histone H3 (Bos taurus)


name: (E)-ferulate + UDP-alpha-D-glucose => 1-O-[(E)-feruloyl]-beta-D-glucose + UDP


name: RAC2 GDIs block activation of RAC2 (Homo sapiens)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GA2 + H(+) + UDP


name: SUMOylation of TDG with SUMO1 (Schizosaccharomyces pombe)


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Canis familiaris)


name: (R)-4'-phosphopantothenate + ATP + L-cysteine = AMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine


name: p-PKR dimer phosphorylates SNCA (Homo sapiens)


name: NPAS4 gene transcription is repressed by KCNIP3 (Homo sapiens)


name: Phospho-cPLA2 translocates to membranes when intracellular calcium levels increase (Gallus gallus)


name: Z-farnesyl diphosphate synthase activity


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphate + H2O => 1-O-(1Z-alkenyl)-2-acyl-sn-glycerol + phosphate


name: Arresten binds integrin alpha1beta1 (Xenopus tropicalis)


name: ST8SIA5 transfers Neu5Ac to gangliosides (Sus scrofa)


name: CHUK, IKBKB phosphorylate CYLD at S418 (Canis familiaris)


name: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O => 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+)


name: 2-(9Z-octadecenoyl)-3-octadecanoyl-sn-glycerol + H(+) + hexadecanoate => 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Caenorhabditis elegans)


name: CLEC1B dimer binds PDPN (Canis familiaris)


name: ATP + CoA + docosanoate => AMP + diphosphate + docosanoyl-CoA


name: ATP + L-arginine <=> ADP + H(+) + N(omega)-phospho-L-arginine


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Xenopus tropicalis)


name: ATP + H2O + nitrate(out) <=> ADP + H(+) + nitrate(in) + phosphate


name: Interaction of SHP1 and KIT (Bos taurus)


name: SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Canis familiaris)


name: Ag(+)(in) + ATP + H2O => ADP + Ag(+)(out) + H(+) + phosphate


name: Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA (Plasmodium falciparum)


name: H(+) + NADPH + O2 + octan-3-one = ethyl hexanoate + H2O + NADP(+)


name: sphinganine 1-phosphate <=> hexadecanal + phosphoethanolamine


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Drosophila melanogaster)


name: (3E,7E)-4,8,12-trimethyltrideca 1,3,7,11-tetraene + but-3-en-2-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => (6E,10E)-geranyllinalool + O2 + reduced [NADPH--hemoprotein reductase]


name: (R)-2-hydroxyhexadecanoate + O2 => CO2 + H2O + pentadecanoate


name: Transesterification to connect viral DNA 3' ends to host DNA 5' ends (Homo sapiens)


name: D-cellotetraose + O2 = D-cellotetraono-1,5-lactone + H2O2


name: PE is converted to PS by PTDSS2 (Rattus norvegicus)


name: 2 H(+) + O2 + 2 sulochrin => 2 (2R)-bisdechlorogeodin + 2 H2O


name: 7-dehydrocholesterol + NADP(+) = 7-dehydrodesmosterol + H(+) + NADPH


name: SYK autophosphorylates at the activated BCR (Homo sapiens)


name: guanidinoacetate + S-adenosyl-L-methionine => creatine + H(+) + S-adenosyl-L-homocysteine


name: Co-precorrin-3 + S-adenosyl-L-methionine = Co-precorrin-4 + S-adenosyl-L-homocysteine


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Homo sapiens)


name: PLK1 phosphorylates FIRMM at S744 (Mus musculus)


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 (Sus scrofa)


name: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose => 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose + H(+)


name: Recruitment of HDAC1 by p107 (RBL1) (Dictyostelium discoideum)


name: Export of peptide loaded MHC class I complex to PM (Rattus norvegicus)


name: SARS virus buds into ERGIC lumen (Homo sapiens)


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Caenorhabditis elegans)


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Canis familiaris)


name: (E)-sinapoyl-CoA + D-glucarate => 2-O-[(E)-sinapoyl]-D-glucarate + CoA


name: PKC alpha interacts with and phosphorylates KIT (Mus musculus)


name: diphosphate + IMP => 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Rattus norvegicus)


name: carnosine + H2O <=> beta-alanine + L-histidine


name: deoxylimononate D-ring-lactone + H(+) => deoxylimonoate + H2O


name: L-aspartate + NADP(+) = H(+) + iminosuccinate + NADPH


name: keto-L-sorbose + O2 => 5-dehydro-D-fructose + H2O2


name: HPD dioxygenates HPP (Drosophila melanogaster)


name: H(+)(in) + L-idonate(in) = H(+)(out) + L-idonate(out)


name: a ganglioside GA1 + N-acetylneuraminate => a ganglioside GM1b + H2O


name: (9Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: ABP1 binds SHANK proteins (Mus musculus)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Rattus norvegicus)


name: RIP3 binds TICAM1 within TLR3 complex to mediate necroptosis  (Homo sapiens)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Bos taurus)


name: Activated FGFR1 phosphorylates FRS2 (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O = a 1-acyl-sn-glycero-3-phosphate + a fatty acid + H(+)


name: NUDT12 hydrolyses NADH to NMNH (Schizosaccharomyces pombe)


name: an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] 5-O-beta-D-glucoside + H(+) + UDP => an anthocyanidin 3-O-[2-O-(4-coumaroyl)-alpha-L-rhamnosyl-(1->6)-beta-D-glucoside] + UDP-alpha-D-glucose


name: 1-octadecanoyl-sn-glycero-3-phosphoserine + 10-hydroxyoctadecanoate + H(+) => 1-octadecanoyl-2-(10-hydroxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O


name: 4-acetoxyphenol + H2O + NADP(+) => 4'-hydroxyacetophenone + H(+) + NADPH + O2


name: SLCOs, SLC16A2 transport T3,T4 from extracellular region to cytosol (Gallus gallus)


name: argininosuccinate <=> fumarate + arginine (Bos taurus)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Drosophila melanogaster)


name: TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Homo sapiens)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Homo sapiens)


name: STAT1,STAT3,STAT6 bind IL13:IL13R type II (Mus musculus)


name: Release of platelet secretory granule components (Xenopus tropicalis)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Rattus norvegicus)


name: A + peniprequinolone <=> AH2 + yaequinolone E


name: (2E)-3-methyl-5-phosphooxypent-2-enoate + H2O => (R)-5-phosphomevalonate


name: Nucleotide exchange on RAB1 (Xenopus tropicalis)


name: RABGGTA and RABGGTB bind (Dictyostelium discoideum)


name: cyclohexane-1-carboxylate + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + trans-4-hydroxycyclohexane-1-carboxylate


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Gallus gallus)


name: 2,4,6-trinitrotoluene + AH2 + glutathione => A + H2O + S-(2,6-dinitro-4-hydroxylaminotoluyl)glutathione


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Dictyostelium discoideum)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Plasmodium falciparum)


name: Cytosolic folate export across the plasma membrane (Saccharomyces cerevisiae)


name: Tankyrase ADP-ribosylates AXIN (Canis familiaris)


name: dodecanoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] <=> (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG (Homo sapiens)


name: CD55 (DAF) promotes C3bBb/C4bC2a dissociation (Xenopus tropicalis)


name: NCOA1 binds ESR1:estrogen:TGFA gene (Mus musculus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Drosophila melanogaster)


name: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate => cyclic pyranopterin phosphate + diphosphate


name: VD3 dissociates from GC (Rattus norvegicus)


name: H2O + N(2)-acetyl-L-citrulline => acetate + L-citrulline


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) (Canis familiaris)


name: Tryptophan is hydroxylated (Dictyostelium discoideum)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Sus scrofa)


name: ERK1/2/5 activate RSK1/2/3 (Saccharomyces cerevisiae)


name: N-terminal L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine => H(+) + N-terminal N-methyl-L-alanyl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Bos taurus)


name: H(+) + L-methionyl(47)-[F-actin] + NADPH + O2 => H2O + L-methionyl(47)-(R)-S-oxide-[F-actin] + NADP(+)


name: Cholesta-5,7,24-trien-3beta-ol is reduced to desmosterol (Homo sapiens)


name: 3 S-adenosyl-L-methionine + tricetin => 3',4',5'-O-trimethyltricetin + 3 H(+) + 3 S-adenosyl-L-homocysteine


name: 1,2-epoxypropane + H2O <=> propane-1,2-diol


name: 2-methyl-L-serine <=> formaldehyde + L-alanine


name: ATP + L-seryl-[tau protein] = ADP + H(+) + O-phospho-L-seryl-[tau protein]


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) <=> a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out)


name: p-ULK1 phosphorylates DENND3 (Canis familiaris)


name: CCND1 recruits HDAC4 to RUNX3 (Homo sapiens)


name: PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Danio rerio)


name: a secondary alkyl amine + H2O + NAD(+) <=> a ketone + H(+) + NADH + NH4(+)


name: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H2O = CoA + L-2-acetamido-6-oxoheptanedioate


name: 3-oxotetracosanoyl-CoA + CO2 + CoA => docosanoyl-CoA + H(+) + malonyl-CoA


name: H2O + N-(9Z-octadecenoyl)-(4R)-hydroxysphinganine <=> (4R)-hydroxysphinganine + (9Z)-octadecenoate


name: [(1->4)-alpha-D-glucosyl](n) + n ATP + n H2O => [(1->4)-6-phospho-alpha-D-glucosyl](n) + n AMP + 2n H(+) + n phosphate


name: (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + D-alanine + H2O


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate => ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate


name: indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose => 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP


name: ADH5 oxidises S-HMGSH to S-FGSH (Mus musculus)


name: NCOA1 binds ESR1:estrogen:TGFA gene (Homo sapiens)


name: NAT1,2 acetylate APAP-Cys to APAP-Mer (Homo sapiens)


name: Frataxin binds iron (Xenopus tropicalis)


name: MCM8 binds CDC6 (Drosophila melanogaster)


name: 9alpha,11alpha-methylene thromboxane A2 + O2 + reduced [NADPH--hemoprotein reductase] = 19-hydroxy-9alpha,11alpha-methylene thromboxane A2 + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] => 4beta-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated (Canis familiaris)


name: H2O + S-3-(hexan-1-ol)-L-cysteine => 3-sulfanyl-1-hexanol + NH4(+) + pyruvate


name: CTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin cytosine dinucleotide


name: FGFR2c mutants bind an expanded range of ligands (Homo sapiens)


name: Dimeric TGF-beta-1 binds to the receptor (Mus musculus)


name: beta-D-galactosyl-(1<->1)-sphing-4-enine + H2O => D-galactose + sphing-4-enine


name: (2E,6E)-farnesyl diphosphate <=> (1S,2S,4R)-beta-elemene + diphosphate


name: ASAH1 hydrolyzes ceramide (Caenorhabditis elegans)


name: Terminal (3' end) cleavage of viral DNA (Homo sapiens)


name: ALOX5 oxidises 14(S)-Hp-DHA to 7(S),14(S)-diHp-DHA (Danio rerio)


name: PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Danio rerio)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Xenopus tropicalis)


name: RAB3 GEFs exchange GTP for GDP on RAB3A (Saccharomyces cerevisiae)


name: 2-methylcyclopentanamine + H2O + NADP(+) => 2-methylcyclopentanone + H(+) + NADPH + NH4(+)


name: RAC1,RAC2,RHOG activate PI3K (Xenopus tropicalis)


name: GGPS1 hexamer transfers IPPP to DMAPP (Homo sapiens)


name: BRWD1 binds SMARCA4 (Drosophila melanogaster)


name: adenosine(N)/adenosine(N+1) in rRNA + 4 S-adenosyl-L-methionine <=> 4 H(+) + N(6)-dimethyladenosine(N)/N(6)-dimethyladenosine(N+1) in rRNA + 4 S-adenosyl-L-homocysteine


name: Gq activation by TP receptor (Gallus gallus)


name: AVPR2 bind desmopressin (Xenopus tropicalis)


name: Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)


name: a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: DHTKD1 dimer decarboxylates 2-OA (Dictyostelium discoideum)


name: ent-copalyl diphosphate <=> diphosphate + dolabradiene


name: acetyl-CoA + L-lysyl-[histone] <=> CoA + H(+) + N(6)-acetyl-L-lysyl-[histone]


name: 2-oxoglutarate + O2 + octanoyl-CoA => 2-hydroxyoctanoyl-CoA + CO2 + succinate


name: BH2 binding can lead to eNOS uncoupling (Dictyostelium discoideum)


name: methylgalactoside transmembrane transporter activity


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Homo sapiens)


name: 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H(+) => chlorohydroquinone + O2


name: Stalling of DNA replication fork and RPA binding (Gallus gallus)


name: CBX4 (Pc2) SUMOylates HNRNPK with SUMO2 (Xenopus tropicalis)


name: L-phenylalanine + O2 = 2-phenylacetamide + CO2 + H2O


name: 2-methylpropanoyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] <=> CoA + N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein]


name: H(+) + L-proline betaine + NADPH + O2 => formaldehyde + H2O + N-methyl-L-proline + NADP(+)


name: aralkylamine dehydrogenase (azurin) activity


name: (R)-miconazole(in) + ATP + H2O <=> (R)-miconazole(out) + ADP + H(+) + phosphate


name: 2 catechol + O2 <=> 2 1,2-benzoquinone + 2 H2O


name: H2O + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2) => beta-D-mannose + N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2)


name: [phosphate](n) + D-glucose = [phosphate](n-1) + D-glucose 6-phosphate + H(+)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(9Z,12Z)-octadecadienoyl-sn-glycerol + 9-(9Z,12Z-octadecadienoyloxy)-octadecanoate


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Caenorhabditis elegans)


name: Formation of Malonyl-CoA from Acetyl-CoA (liver) (Schizosaccharomyces pombe)


name: DNA nucleases bind monoubiquitinated ID2 complex (Canis familiaris)


name: dioscin + 2 H2O = diosgenin 3-O-beta-D-glucoside + 2 L-rhamnopyranose


name: diphosphate + rhizathalene A => (2E,6E,10E)-geranylgeranyl diphosphate


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Canis familiaris)


name: ALOX5 oxidises 14(S)-Hp-DPAn-3 to MaR3n-3 DPA (Bos taurus)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Dictyostelium discoideum)


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe (Rattus norvegicus)


name: 3-methyl-2-oxobutanoate + O-acetyl-L-homoserine => (6S)-6-amino-3,3-dimethyl-2-oxoheptanedioate + acetate + H(+)


name: PNP catalyzes the conversion of (deoxy)inosine to hypoxanthine and (deoxy)ribose (Mus musculus)


name: KDM6B binds iron (Schizosaccharomyces pombe)


name: Cargo-carrying vesicles bud from the TGN (Homo sapiens)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Sus scrofa)


name: 4-hydroxy-3-all-trans-heptaprenylbenzoate + diphosphate => 4-hydroxybenzoate + all-trans-heptaprenyl diphosphate


name: RHOG binds effectors at the plasma membrane (Danio rerio)


name: Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Danio rerio)


name: 7(1)-hydroxychlorophyllide a + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] => chlorophyllide a + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: H2O + N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein] = 3-deoxyglucosone + L-lysyl-[protein] + phosphate


name: Activation of Cdc25C (Caenorhabditis elegans)


name: Persulfide sulfur is dioxygenated (Caenorhabditis elegans)


name: docosanoyl-CoA + glycine <=> CoA + H(+) + N-docosanoylglycine


name: Activated FGFR1 phosphorylates FRS3 (Drosophila melanogaster)


name: SLC9A9 exchanges Na+ for H+ across the late endosome membrane (Dictyostelium discoideum)


name: O2 + 4 tellimagrandin II <=> 2 cornusiin E + 2 H2O


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: Activated FGFR1 binds FRS3 (Rattus norvegicus)


name: acetyl-CoA + ATP + 11 H(+) + L-serine + 7 malonyl-CoA + 8 NADPH + 2 S-adenosyl-L-methionine => (5S)-3-[(2E,6R,8E,10E,12E)-2,6-dimethyltetradeca-2,8,10,12-tetraenoyl]-5-(hydroxymethyl)pyrrolidine-2,4-dione + AMP + 7 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 2 S-adenosyl-L-homocysteine


name: C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Drosophila melanogaster)


name: 2-hydroxy-2-methylpropanenitrile + UDP-alpha-D-glucose => H(+) + linamarin + UDP


name: ATP + thiamine diphosphate => ADP + thiamine triphosphate


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Canis familiaris)


name: GUCYs converts GTP to cGMP (Canis familiaris)


name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Homo sapiens)


name: Melanospin is stimulated by light (Bos taurus)


name: 2,5-dichlorohydroquinone + H(+) + NADH => 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + NAD(+)


name: PP2A-PP2R5C dephosphorylates MDM2 (Homo sapiens)


name: oxidized [plastocyanin] + reduced [2Fe-2S]-[ferredoxin] => hnu + oxidized [2Fe-2S]-[ferredoxin] + reduced [plastocyanin]


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Mus musculus)


name: H2O + hexadecanedioyl-CoA <=> CoA + H(+) + hexadecanedioate


name: D-maltohexaose + H2O = alpha-D-glucose + D-maltopentaose


name: NADP(+) + reduced riboflavin <=> 2 H(+) + NADPH + riboflavin


name: TIRAP binds PIP2-rich regions in the plasma membrane (Xenopus tropicalis)


name: a ganglioside Ac-O-7-GD1a (d18:1(4E)) + CoA => a ganglioside GD1a (d18:1(4E)) + acetyl-CoA


name: MKRN1 polyubiquitinates PTEN (Schizosaccharomyces pombe)


name: ARL6:GTP and the BBSome bind ciliary cargo (Gallus gallus)


name: T1R2/T1R3 dimer is a sweet taste receptor (Bos taurus)


name: 3-dehydroshikimate + H2O => 3-dehydroquinate


name: ATP Hydrolysis By Myosin (Canis familiaris)


name: PP2A-B56 dephosphorylates centromeric cohesin (Rattus norvegicus)


name: (4Z,15Z)-bilirubin IXalpha + NADP(+) <=> biliverdin IXalpha + H(+) + NADPH


name: an N-acylsphing-4-enine 1-phosphate(in) = an N-acylsphing-4-enine 1-phosphate(out)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Danio rerio)


name: AVPR1A,B,2 bind atosiban (Gallus gallus)


name: CUL3:RBX1 ubiquitinates KEAP1 (Bos taurus)


name: P2RY12 binds P2RY12 antagonists (Homo sapiens)


name: H2O + S-(4-hydroxy-3-methylbutan-2-yl)-L-cysteine <=> 2-methyl-3-sulfanylbutan-1-ol + NH4(+) + pyruvate


name: phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex (Homo sapiens)


name: HLA-G specific inhibitory MHC class Ib receptor activity


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + decanoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-decanoyl-sn-glycerol + CoA


name: STING dimerization (Drosophila melanogaster)


name: (11Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(13Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Drosophila melanogaster)


name: [mycofactocin precursor peptide]-C-terminal glycyl-L-valyl-L-tyrosine + S-adenosyl-L-methionine => 5'-deoxyadenosine + [mycofactocin precursor peptide]-C-terminal glycyl-N-{[2-(4-hydroxyphenyl)ethenyl]-3-methylbutanamide} + CO2 + L-methionine


name: aldehydo-N-acetyl-D-mannosamine + H2O + phosphoenolpyruvate => N-acetylneuraminate + phosphate


name: 24-methylidenelophenol + 6 Fe(II)-[cytochrome b5] + 5 H(+) + 3 O2 => 4alpha-carboxy-ergosta-7,24(24(1))-dien-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: Proinsulin translocates from the endoplasmic reticulum to the Golgi (Gallus gallus)


name: FGF2:TGFBR3 binding to GIPC1 (Sus scrofa)


name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region (Mus musculus)


name: JNK-dependent inhibition of TP53 ubiquitination (Homo sapiens)


name: 2 Fe(III)-[cytochrome c] + NADPH <=> 2 Fe(II)-[cytochrome c] + H(+) + NADP(+)


name: Cytosolic PP2A dephosphorylates phosphorylated PER complexed with TIM and DCO (Drosophila melanogaster)


name: A + D-cellobiose => AH2 + D-cellobiono-1,5-lactone


name: dihydroxyacetone phosphate = methylglyoxal + phosphate


name: cholesterol + O2 + reduced [NADPH--hemoprotein reductase] = (22S)-22-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (-)-dehydrodiconiferyl acid ketone + a quinone + H2O <=> (-)-dehydrodiconiferyl acid carboxylate + a quinol + H(+)


name: MAPK-dependent phosphorylation of KARS (Sus scrofa)


name: OMA1 hydrolyzes YME1L1 (Xenopus tropicalis)


name: SEC24A,B:SEC23A bind SEC22B (Rattus norvegicus)


name: formate dehydrogenase (quinone) activity


name: acetate:monoatomic cation symporter activity


name: dimethylallyl diphosphate + preechinulin => diphosphate + tardioxopiperazine B


name: 4 (R)-methylmalonyl-CoA + 12 H(+) + long-chain fatty acyl-[mycocerosate synthase] + 8 NADPH <=> 4 CO2 + 4 CoA + 4 H2O + 8 NADP(+) + tetramethylated-mycocerosoyl-[mycocerosate synthase]


name: [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + H(+) + NADPH => [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + NADP(+) + phosphate


name: 1-octadecanoyl-2-(15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-2-acetyl-sn-glycerol => a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: 2 (S)-lactate(in) + prostaglandin E3(out) => 2 (S)-lactate(out) + prostaglandin E3(in)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+) + octadecanoate


name: ERBB2 homodimer phosphorylates SHC1 (Homo sapiens)


name: TNRC6A:AGO2:miRNA is transported into the nucleus (Sus scrofa)


name: 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + dimethylallyl diphosphate = 1-hydroxy-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + diphosphate


name: pyruvate + ubiquinol-8 => (R)-lactate + ubiquinone-8


name: 3'-phosphoadenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: (2Z,6Z)-farnesyl diphosphate <=> alpha-humulene + diphosphate


name: adenosine(2142) in 25S rRNA + S-adenosyl-L-methionine => H(+) + N(1)-methyladenosine(2142) in 25S rRNA + S-adenosyl-L-homocysteine


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Bos taurus)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Bos taurus)


name: ALOX5 oxidises 18(R)-HEPE to 5(S)-Hp-18(R)-HEPE (Dictyostelium discoideum)


name: D-cellotetraono-1,5-lactone + H2O <=> D-cellotetraonate + H(+)


name: MUS81:EME1,EME2 cleaves D-loop (Bos taurus)


name: isovitexin + UDP-alpha-D-glucose => H(+) + isovitexin 2''-O-beta-D-glucoside + UDP


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Rattus norvegicus)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Rattus norvegicus)


name: ATP + H2O + Pb(2+)(in) = ADP + H(+) + Pb(2+)(out) + phosphate


name: RUNX1 binds the SWI/SNF complex (Drosophila melanogaster)


name: DLD dimer dehydrogenates dihydrolipoyl (Schizosaccharomyces pombe)


name: PXLP-K56-SRR dimer deaminates D-Ser (Canis familiaris)


name: ABCF1 binds EIF2 (Caenorhabditis elegans)


name: SCARB1:ligand is endocytosed (Sus scrofa)


name: DHCR24 reduces LAN to 24,25-dhLAN (Homo sapiens)


name: PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA (Xenopus tropicalis)


name: GGCT transforms gGluCys to OPRO (Danio rerio)


name: OPLAH hydrolyses OPRO to L-Glu (Schizosaccharomyces pombe)


name: a cytidine in rRNA + S-adenosyl-L-methionine => a 5-methylcytidine in rRNA + H(+) + S-adenosyl-L-homocysteine


name: SHP2 interacts with p-KIT (Homo sapiens)


name: butanoate + cyclohexane-1-carbonyl-CoA => butanoyl-CoA + cyclohexane-1-carboxylate


name: H(+) + NADPH + O2 + tigecycline => 11a-hydroxytigecycline + H2O + NADP(+)


name: Arachidonate is hydroxylated to 20-HETE by CYP(3) (Sus scrofa)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a 3-acyl-sn-glycerol = a 1,3-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: MLKL binds PDCD6IP and SDCBP (Homo sapiens)


name: a quinone + succinate = a quinol + fumarate


name: (E,E)-piperoyl-CoA + AMP + H(+) => (E,E)-piperoyl-AMP + CoA


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Saccharomyces cerevisiae)


name: RAB8A,10,13,14 exchange GDP for GTP (Homo sapiens)


name: 3-(4-hydroxyphenyl)pyruvate + H(+) => (4-hydroxyphenyl)acetaldehyde + CO2


name: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 <=> a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O


name: 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + 2 H(+) + phosphate => 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O


name: a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(out) => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine(in)


name: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + NAD(+) = bacteriochlorophyllide a + H(+) + NADH


name: PGLYRP1 binds bacterial peptidoglycan (Drosophila melanogaster)


name: zinc ion transmembrane transporter activity


name: dodecanoate + O2 + reduced [NADPH--hemoprotein reductase] => 12-hydroxydodecanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Association of procollagen type XXII (Mus musculus)


name: (S)-2-amino-6-oxohexanoate + guanidine => 6-hydroxy-L-homoarginine


name: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-alpha-aminoacyl-[protein]


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Mus musculus)


name: 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Saccharomyces cerevisiae)


name: tricarboxylate secondary active transmembrane transporter activity


name: AMP + diphosphate + hexadecanoyl-[(hydroxy)phthioceranic acid synthase] => ATP + hexadecanoate + holo-[(hydroxy)phthioceranic acid synthase]


name: ADP(in) + ATP(out) + H(+)(in) + Mg(2+)(out) => ADP(out) + ATP(in) + H(+)(out) + Mg(2+)(in)


name: glutaryl-CoA + 2 H(+) + oxidized [electron-transfer flavoprotein] <=> (2E)-butenoyl-CoA + CO2 + reduced [electron-transfer flavoprotein]


name: NCOA1(868-1441) binds PAX3(1-319) (Sus scrofa)


name: 3,4-dihydroxyphenylacetaldehyde + H2O2 + NH4(+) => dopamine + H2O + O2


name: ATP7B transports cytosolic Cu2+ to Golgi lumen (Canis familiaris)


name: (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate + H2O => (R)-glycerate + alpha-D-mannose 6-phosphate


name: glycochenodeoxycholate + H2O => chenodeoxycholate + glycine


name: L-glutamine(in) + L-threonine(out) + Na(+)(out) <=> L-glutamine(out) + L-threonine(in) + Na(+)(in)


name: a secondary alcohol + NAD(+) <=> a ketone + H(+) + NADH


name: alpha-D-galactosyl-(1->3)-1D-myo-inositol + sucrose <=> myo-inositol + raffinose


name: Conjugation of SUMO1 to UBA2:SAE1 (Caenorhabditis elegans)


name: (2Z,6E)-farnesyl diphosphate = (6R,7S)-2,2,6-trimethyl-10-methylenebicyclo[5.4.0]undec-1(11)-ene + diphosphate


name: prekallikrein:kininogen:C1q binding protein tetramer -> kallikrein:kininogen:C1q binding protein tetramer (Homo sapiens)


name: AKR dimers reduce AFBDHO to AFBDOH (Danio rerio)


name: pre-sodorifen diphosphate = diphosphate + sodorifen


name: PLA2G2A binds bacterial phospholipids (Homo sapiens)


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Rattus norvegicus)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Mus musculus)


name: ATP + holo-[ACP] + tetradecanoate = AMP + diphosphate + tetradecanoyl-[ACP]


name: diphosphate + dUMP + NH4(+) => dCTP + 2 H2O


name: lactate + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Mus musculus)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + H(+) + malonyl-CoA <=> (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CO2 + CoA


name: an inositol-1-phosphoceramide + GDP-alpha-D-mannose <=> an alpha-mannosylinositol-1-phosphoceramide + GDP + H(+)


name: proclavaminate + urea => amidinoproclavaminate + H2O


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Bos taurus)


name: D-glucose(in) + Na(+)(in) => D-glucose(out) + Na(+)(out)


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Xenopus tropicalis)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Homo sapiens)


name: a ganglioside GT1a (d18:1(4E)) + H2O => a ganglioside GD1a (d18:1(4E)) + N-acetylneuraminate


name: ATP + D-glucuronate <=> 1-phospho-alpha-D-glucuronate + ADP + H(+)


name: PPARG binds PPARG agonists (Homo sapiens)


name: RHOH binds effectors at the plasma membrane (Xenopus tropicalis)


name: 2 Na(+)(out) + nitrate(out) => 2 Na(+)(in) + nitrate(in)


name: PSMD14 cleaves K63-linked ubiquitin (Schizosaccharomyces pombe)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+) => 1-O-alkyl-2-acyl-sn-glycerol + ATP


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Homo sapiens)


name: H(+) + isovitexin 2''-O-beta-D-glucoside + UDP => isovitexin + UDP-alpha-D-glucose


name: a peptide antigen(in) + ATP + H2O = a peptide antigen(out) + ADP + H(+) + phosphate


name: p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol (Bos taurus)


name: COQ4 decarboxylates MHDB (Schizosaccharomyces pombe)


name: AcK-NFE2L2 binds the BCL2 gene (Homo sapiens)


name: (d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Plasmodium falciparum)


name: CIN85 dissociates from EGF:p-6Y-EGFR:CBL:Beta-Pix:CDC42:GTP:CIN85 (Mus musculus)


name: HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane (Homo sapiens)


name: (2S)-pristanoyl-CoA + O2 => trans-2,3-dehydropristanoyl-CoA + H2O2 (ACOX3) (Danio rerio)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Rattus norvegicus)


name: acetyl-CoA + GDP-alpha-D-perosamine => CoA + GDP-N-acetyl-alpha-D-perosamine + H(+)


name: STAT3 binds to p-Y-IL23R in IL23:IL23 receptor (Homo sapiens)


name: 5-methylaminomethyl-2-(Se-phospho)selenouridine(34) in tRNA + H2O = 5-methylaminomethyl-2-selenouridine(34) in tRNA + phosphate


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Dictyostelium discoideum)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + AH2 + O2 <=> (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + A + 2 H2O


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + AH2 + O2 => A + a (8E,10E,12Z)-octadecatrienoyl-containing glycerolipid + 2 H2O


name: ADAL1 hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Canis familiaris)


name: DNA polymerase epsilon binds at the origin (Rattus norvegicus)


name: 2-hydroxy-4-aminobutanoate => (S)-azetidine-2-carboxylate + H2O


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Caenorhabditis elegans)


name: H(+)(out) + L-lysyl-glycine(out) => H(+)(in) + L-lysyl-glycine(in)


name: Binding of ATR:ATRIP to RPA at resected DNA DSBs (Gallus gallus)


name: a tRNA with a 3' CCA end + ATP + 2 CTP => a tRNA with a 3' CCACCA end + 3 diphosphate


name: MCM4, MCM6 and MCM7 form a heterotrimer (Homo sapiens)


name: Recovery of RNA synthesis after TC-NER (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphoglycerol + H2O => a 2-acyl-sn-glycero-3-phosphoglycerol + a fatty acid + H(+)


name: 4-O-beta-D-glucosyl-trans-ferulate + H2O => 3-hydroxy-3-(4-O-beta-D-glucosyl-3-methoxyphenyl)propanoate


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Homo sapiens)


name: Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + guaiacol + H(+) => catechol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: CPT1A transfers PALM to CAR (Rattus norvegicus)


name: (9Z)-octadecenoyl-CoA + decan-1-ol => 1-O-decyl-(9Z)-octadecenoate + CoA


name: ent-kaur-16-en-19-oate + 4 H(+) + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = gibberellin A12 aldehyde + 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin]


name: sucrose + H2O => glucose + fructose (Schizosaccharomyces pombe)


name: 4-chlorobenzoate + H2O = 4-hydroxybenzoate + chloride + H(+)


name: 2-aminobut-2-enoate + H(+) + hydrogen sulfide => L-homocysteine


name: Disassociation of Processive Complex and Completed Telomere End (Bos taurus)


name: H2O + oxaloacetate + propanoyl-CoA => 2-methylcitrate + CoA + H(+)


name: WNT ligands traffic to the plasma membrane (Canis familiaris)


name: 17beta-hydroxy-5alpha-androstan-3-one + NAD(+) <=> 5alpha-androstan-3,17-dione + H(+) + NADH


name: 2-phenylacetaldehyde + CO2 => 3-phenylpyruvate + H(+)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Sus scrofa)


name: RAD52 promotes single strand annealing at resected DNA DSBs (Mus musculus)


name: Type I Na+-coupled phosphate co-transport (Canis familiaris)


name: (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + O2 + reduced [NADPH--hemoprotein reductase] => 3-dehydro-6-deoxoteasterone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 4-methylbenzaldehyde + H2O2 => 4-methylbenzyl alcohol + O2


name: Binding of RRN3 to RNA Polymerase I (Dictyostelium discoideum)


name: H2O2 + oxidized [rubredoxin] => 2 H(+) + reduced [rubredoxin] + superoxide


name: diphosphate + gamma-terpinene => (2E)-geranyl diphosphate


name: Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA (Bos taurus)


name: beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol <=> cholesteryl 3-beta-D-glucoside + N-dodecanoylsphing-4-enine


name: H(+) + N,N-dihydroxy-L-tetrahomomethionine = (E)-7-(methylsulfanyl)heptanal oxime + CO2 + H2O


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Drosophila melanogaster)


name: D-galactonate(in) + H(+)(in) <=> D-galactonate(out) + H(+)(out)


name: H2O2 + tetradecanoate = (3R)-hydroxytetradecanoate + H2O


name: an NDP-alpha-D-glucose + D-glucose <=> a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H(+)


name: 2 H(+) + NADPH + octanoate => H2O + NADP(+) + octanal


name: PA is converted to CDP-DAG by CDS1 (Saccharomyces cerevisiae)


name: histamine + S-adenosyl-L-methionine <=> H(+) + N(tau)-methylhistamine + S-adenosyl-L-homocysteine


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Gallus gallus)


name: GRK2 binds CALM1:4Ca2+ (Drosophila melanogaster)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + H(+) + NADPH = (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+)


name: 2 L-arginine + 4 O2 + 3 reduced [flavodoxin] = 5 H(+) + 4 H2O + 2 L-citrulline + 2 nitric oxide + 3 oxidized [flavodoxin]


name: 1,2-diheptanoyl-sn-glycero-3-phosphocholine + 1,2-dihexanoyl-sn-glycero-3-phosphocholine => 1-heptanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + 1-hexanoyl-2-heptanoyl-sn-glycero-3-phosphocholine


name: CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) (Canis familiaris)


name: (3S)-hydroxyhexadecanedioyl-CoA => (2E)-hexadecenedioyl-CoA + H2O


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Homo sapiens)


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O


name: H(+) + NADH + S-formylmycothiol => NAD(+) + S-(hydroxymethyl)mycothiol


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Caenorhabditis elegans)


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Rattus norvegicus)


name: oxidoreductase activity, acting on a heme group of donors


name: a fatty acid + ATP + H(+) = a fatty acyl-AMP + diphosphate


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Caenorhabditis elegans)


name: PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)


name: glycyl-L-leucine(out) + 2 H(+)(out) <=> glycyl-L-leucine + 2 H(+)(in)


name: PARVA associates with Paxillin (Mus musculus)


name: PP2A-PP2R5C dephosphorylates MDM2 (Sus scrofa)


name: Activated FGFR2 binds PLCG1 (Gallus gallus)


name: POU5F1 (OCT4), NANOG bind the CDX2 promoter (Homo sapiens)


name: a hydroperoxide + L-cysteinyl-[protein] => an alcohol + S-hydroxy-L-cysteinyl-[protein]


name: lipoxin A4 + NAD(+) => 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + H(+) + NADH


name: ubiquitin-like modifier activating enzyme activity


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Sus scrofa)


name: N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Caenorhabditis elegans)


name: ESR1 binds ESR1 antagonists (Mus musculus)


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Sus scrofa)


name: ATP + D-glucose => ADP + D-glucose 6-phosphate + H(+)


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Drosophila melanogaster)


name: SHP2 binds to the active receptor (Xenopus tropicalis)


name: norspermine + S-adenosyl 3-(methylsulfanyl)propylamine => caldopentamine + 2 H(+) + S-methyl-5'-thioadenosine


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Canis familiaris)


name: acetone + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] + psoralen => (7S)-marmesin + O2 + reduced [NADPH--hemoprotein reductase]


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + dimethylallyl diphosphate => (S)-3-{[2-(1,1-dimethylallyl)-indol-3-yl]methyl}-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + diphosphate


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Sus scrofa)


name: PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Bos taurus)


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Danio rerio)


name: H2O2 + 2 L-ascorbate => 2 H2O + 2 monodehydro-L-ascorbate radical


name: HYAL1 hydrolyses Chondroitin chains (Bos taurus)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Canis familiaris)


name: IL26:IL20RA:JAK1 binds IL10RB:TYK2 (Sus scrofa)


name: (R)-3-hydroxy-(13Z)-eicosenoyl-CoA <=> (2E,13Z)-eicosadienoyl-CoA + H2O


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Plasmodium falciparum)


name: CAMK1 phosphorylates ARHGEF7-1 (Homo sapiens)


name: PKA phosphorylates DARPP-32 on Thr34 (Mus musculus)


name: AOX1 oxidises PXL to PDXate (Bos taurus)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Rattus norvegicus)


name: pyridoxamine + pyruvate <=> L-alanine + pyridoxal


name: Resynthesis of excised residue by POLB (Canis familiaris)


name: SEC22B, CALR, STX4, TAP and TAPBP bind (Homo sapiens)


name: Arresten binds integrin alpha1beta1 (Bos taurus)


name: a primary nitroalkane + H2O + O2 <=> an aldehyde + H(+) + H2O2 + nitrite


name: Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen (Xenopus tropicalis)


name: Autophosphorylation of PAK1 (Dictyostelium discoideum)


name: Activated FGFR4:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)


name: (22R,23R)-22,23-dihydroxycampesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => (22S)-22-hydroxycampesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: (R)-carnitine + hexanoyl-CoA = CoA + O-hexanoyl-(R)-carnitine


name: PTEN undergoes monoubiquitination (Bos taurus)


name: p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Homo sapiens)


name: a 12-sulfojasmonate + adenosine 3',5'-bisphosphate + H(+) => 3'-phosphoadenylyl sulfate + a 12-hydroxyjasmonate


name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Saccharomyces cerevisiae)


name: Dissociation of IRS-P from insulin receptor (Sus scrofa)


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Drosophila melanogaster)


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Homo sapiens)


name: (1'S,5'S)-5'-hydroxyaverantin + NAD(+) <=> (S)-5'-oxoaverantin + H(+) + NADH


name: Activated FGFR2 phosphorylates PPTN11 (Homo sapiens)


name: H2O + N-octadecanoyl-L-phenylalanine => L-phenylalanine + octadecanoate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Mus musculus)


name: B3GALTL transfers glucose to O-fucosyl-proteins (Homo sapiens)


name: 2 A + all-trans-4,4'-diapolycopene-4,4'-dial + 2 H2O => 2 AH2 + all-trans-4,4'-diapolycopene-4,4'-dioate + 2 H(+)


name: H(+) + H2O + tetracenomycin D3 => O2 + tetracenomycin F1


name: PP2A dephosphorylates BANF1 (Homo sapiens)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Sus scrofa)


name: O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + H(+) + UDP


name: H(+) + NADPH + O2 + tetracycline => 11a-hydroxytetracycline + H2O + NADP(+)


name: a di-trans,poly-cis-dolichyl phosphate + UDP-alpha-D-xylose = a di-trans,poly-cis-dolichyl D-xylosyl phosphate  + UDP


name: 3-dehydro-D-glucose + D-glucose => 3'-dehydromaltose + H2O


name: Necl-2:Nectin 3 trans heterodimer interaction (Homo sapiens)


name: H2O + N,N-dimethylglycine + oxidized 2[4Fe-4S]-[ferredoxin] = formaldehyde + 2 H(+) + reduced 2[4Fe-4S]-[ferredoxin] + sarcosine


name: SKI complexes with the Smad complex, suppressing BMP2 signalling (Canis familiaris)


name: KIAA0101 double monoubiquitination (Sus scrofa)


name: MME:Zn2+ binds sacubitrilat (Xenopus tropicalis)


name: PLK3 phosphorylates TP53 (Canis familiaris)


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Mus musculus)


name: p-S446-IRF5 dimer translocates to the nucleus (Bos taurus)


name: HIF-alpha translocates from cytosol to nucleus (Gallus gallus)


name: Conversion of C4 into C4a and C4b (Sus scrofa)


name: 4-aminobenzoate + 2 H(+) + NADPH + O2 => 4-aminophenol + CO2 + H2O + NADP(+)


name: acetyl-CoA + 2n H(+) + n malonyl-CoA + 2n NADPH = a long-chain fatty acid + n CO2 + (n+1) CoA + 2n NADP(+)


name: MDM2 polyubiquitinates RUNX3 (Sus scrofa)


name: CYP19A1 hydroxylates ANDST to E1 (Xenopus tropicalis)


name: Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA (Mus musculus)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Gallus gallus)


name: USP10 deubiquitinates SNX3, CFTR (Schizosaccharomyces pombe)


name: COX7A1 gene expression is stimulated by EBF2 (Homo sapiens)


name: MASTL phosphorylates ENSA (Gallus gallus)


name: Carbonic anhydrase dehydrates bicarbonate (mitochondria) (Rattus norvegicus)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z)-octadecenoate + 3-(9Z-octadecenoyl)-sn-glycerol + H(+)


name: ATP + glycerol 2-phosphate(out) + H2O = ADP + glycerol 2-phosphate(in) + H(+) + phosphate


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate <=> 1,3-di-(9Z-octadecenoyl)-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + hexadecanoyl-CoA => 1-O-hexadecyl-2-acetyl-3-hexadecanoyl-sn-glycerol + CoA


name: FOXA1 and GATA3 bind to CCND1 promoter (Canis familiaris)


name: chloride(out) + oxalate(in) => chloride(in) + oxalate(out)


name: H2O + N,1-diacyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-3-phosphate + an N-acylethanolamine + H(+)


name: Trafficking of GluR1-containing  AMPA receptors (Rattus norvegicus)


name: H2O + L-2-aminopentanoate + O2 => 2-oxopentanoate + H2O2 + NH4(+)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) <=> 2 H(+) + L-erythro-biopterin + 2 NADPH


name: Defective CYP26B1 does not 4-hydroxylate atRA (Homo sapiens)


name: 2 acetyl-CoA <=> acetoacetyl-CoA + CoA (Canis familiaris)


name: (2S)-3-sulfopropanediol => 3-oxopropane-1-sulfonate + H2O


name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Sus scrofa)


name: diphosphate + docosanoyl-AMP => ATP + docosanoate + H(+)


name: D-arabinose + NADP(+) <=> D-arabinono-1,4-lactone + H(+) + NADPH


name: NUDT12 hydrolyses NADH to NMNH (Rattus norvegicus)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Bos taurus)


name: H2O + N-acetyl-(2S,6S)-2,6-diaminoheptanedioate <=> (2S,6S)-2,6-diaminoheptanedioate + acetate


name: GRB2:SOS1 complex binds to the active receptor (Gallus gallus)


name: CAD hexamer dehydrates N-carb-L-Asp to (S)-DHO (Bos taurus)


name: HPN heterodimer cleaves pro-MST1 to form MST1 dimer (Homo sapiens)


name: RUNX3 binds the NOTCH1 coactivator complex (Sus scrofa)


name: EPOR binds EPOR agonists (Xenopus tropicalis)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 (Homo sapiens)


name: OCT3 mediates renal clearance of organic cations (Homo sapiens)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Mus musculus)


name: Cytosolic VBC complex ubiquitinylates hydroxyprolyl-HIF-alpha  (Drosophila melanogaster)


name: a 5,6-dihydrouridine in tRNA + NAD(+) => a uridine in tRNA + H(+) + NADH


name: SMURF1/2 ubiquitinates PRICKLE1 (Bos taurus)


name: CoA + thioacetate => acetyl-CoA + hydrogen sulfide


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Xenopus tropicalis)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Saccharomyces cerevisiae)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphate


name: Integrin alphaXbeta2 binds JAM3 (Homo sapiens)


name: abieta-7,13-diene + O2 + reduced [NADPH--hemoprotein reductase] <=> abieta-7,13-dien-18-ol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ATP + N-hexadecanoylsphing-4-enine <=> ADP + H(+) + N-(hexadecanoyl)-sphing-4-enine-1-phosphate


name: A + H2O + thymine = 5-methylbarbiturate + AH2 + H(+)


name: chloride + FADH2 + L-tryptophan + O2 = 6-chloro-L-tryptophan + FAD + 2 H2O


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Active MTORC1 binds the ULK1 complex (Mus musculus)


name: Association of procollagen type IV (Canis familiaris)


name: mandelate + O2 => H2O2 + phenylglyoxylate


name: an inositol-1-phosphophytoceramide + beta-D-mannose <=> a mannosylinositol-1-phosphophytoceramide + H2O


name: FMNH2 + NADH + O2 + uracil = (Z)-3-ureidoacrylate + FMN + H(+) + H2O + NAD(+)


name: chloride(out) + D-alanine(out) + 2 Na(+)(out) <=> chloride(in) + D-alanine(in) + 2 Na(+)(in)


name: a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H(+) + sulfate => a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O


name: The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Bos taurus)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Homo sapiens)


name: Polyadenylation of respiratory syncytial virus subgenomic positive-sense mRNAs (Homo sapiens)


name: (2E,6E)-farnesyl diphosphate => allo-aromadendrene + diphosphate


name: [thioredoxin]-disulfide + AMP + 2 H(+) + sulfite => [thioredoxin]-dithiol + adenosine 5'-phosphosulfate


name: a 2,3-saturated acyl-CoA + FAD + H(+) = a (2E)-enoyl-CoA + FADH2


name: TFPA2A homodimer and NPM1 bind the MYBL2 gene promoter (Homo sapiens)


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Homo sapiens)


name: a 3',5'-unsubstituted flavanone + O2 + reduced [NADPH--hemoprotein reductase] => a 3'-hydroxy,5'-unsubstituted flavanone + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (9Z)-octadecenoate + AH2 + O2 => (12R)-hydroxy-(9Z)-octadecenoate + A + H2O


name: D-ribulose 1,5-bisphosphate + H2O = D-ribulose 1-phosphate + phosphate


name: FMN-N(5)-peroxide + thymine <=> (Z)-2-methylureidoacrylate + FMN-N(5)-oxide + 2 H(+)


name: 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + H(+) + S-adenosyl-L-homocysteine => 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine


name: methylarsonous acid + S-adenosyl-L-methionine = dimethylarsinate + 2 H(+) + S-adenosyl-L-homocysteine


name: IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3 binds STAT5 (Mus musculus)


name: (indol-3-yl)acetate + CO2 + H2O + NADP(+) => H(+) + indole-3-pyruvate + NADPH + O2


name: 3'-phosphoadenylyl sulfate + dopamine => adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + H(+)


name: (R)-S-lactoylglutathione + H2O <=> (R)-lactate + glutathione + H(+)


name: Formation of the Spliceosomal E complex (Sus scrofa)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Rattus norvegicus)


name: phosphate + S-methyl-5'-thioinosine = hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate


name: Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)


name: a ganglioside GD1a (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GalNAc-GD1a (d18:1(4E)) + H(+) + UDP


name: ATP + H2O + L-leucine(out) = ADP + H(+) + L-leucine(in) + phosphate


name: H2O + NADP(+) + semiviriditoxin => (3S)-9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H,3H,4H-naphtho[2,3-c]pyran-1-one + H(+) + NADPH + O2


name: PA is converted to CDP-DAG by CDS2 (Rattus norvegicus)


name: IL10 dimer binds IL10RA:JAK1 (Canis familiaris)


name: Complement factor I complex formation (Canis familiaris)


name: Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Bos taurus)


name: (9R)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O => (9Z,12Z)-octadecadienoate + AH2 + O2


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H(+) + octadecanoate


name: ATP + CoA + propanoate = AMP + diphosphate + propanoyl-CoA


name: a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = a di-trans,poly-cis-dolichyl diphosphate + H(+) + N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginy-[protein]


name: Endonucleolytic RISC hydrolyzes target RNAs (Bos taurus)


name: IL15:IL15RA:IL2RB:JAK1:IL2RG:p-JAK3:p-Y-SHC1:GRB2 binds GAB2 (Homo sapiens)


name: a 2-demethylmenaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine => 5'-deoxyadenosine + a 2-demethyl-8-methylmenaquinone + 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L-homocysteine


name: 12,13-dihydroxy-(9Z)-octadecenoate => 12,13-epoxy-(9Z)-octadecenoate + H2O


name: biphenyl-2,2'-diol + H(+) + NADH + O2 => biphenyl-2,2',3-triol + H2O + NAD(+)


name: (3E)-2-oxohex-3-enedioate + H(+) = 2-oxopent-4-enoate + CO2


name: an inositol phosphomannosyl-alpha-1->6-inositol-1-phospho-N-acyl-4R-hydroxysphinganine + H2O => alpha-D-mannosyl-di-(inositol-1-phosphate) + an N-acyl-(4R)-4-hydroxysphinganine + H(+)


name: acetyl-CoA + GDP-alpha-D-perosamine <=> CoA + GDP-N-acetyl-alpha-D-perosamine + H(+)


name: Gi activation by P2Y purinoceptor 12 (Sus scrofa)


name: delphinidin 3-O-beta-D-glucoside + UDP => delphinidin + UDP-alpha-D-glucose


name: FAR2 reduces PalmCoA to HXOL (Bos taurus)


name: 5'-deoxyadenosine + A + alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H(+) + L-methionine + methane => AH2 + alpha-D-ribose 1-methylphosphonate 5-phosphate + S-adenosyl-L-methionine


name: (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O2 = (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H(+)


name: phosphate(in) + 2 thiosulfate(out) => phosphate(out) + 2 thiosulfate(in)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Danio rerio)


name: 3-oxooctanedioyl-CoA + CoA => acetyl-CoA + hexanedioyl-CoA


name: acetyl-CoA + N-terminal L-methionyl-L-lysyl-[protein] => CoA + H(+) + N-terminal N(alpha)-acetyl-L-methionyl-L-lysyl-[protein]


name: 2xPDXK:2xZn2+ phosphorylates PXL (Canis familiaris)


name: an S-substituted L-cysteine + H2O <=> a thiol + NH4(+) + pyruvate


name: 11-oxocucurbitadienol + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] => cucurbitadienol + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Canis familiaris)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG2 (Caenorhabditis elegans)


name: CYP27A1 27-hydroxylates CHOL (Mus musculus)


name: OGG1beta translocates to mitochondria (Plasmodium falciparum)


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Saccharomyces cerevisiae)


name: glycine + H(+) + succinyl-CoA <=> 5-aminolevulinate + CO2 + CoA


name: SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Homo sapiens)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Mus musculus)


name: TAK1 associated with the CBM complex phosphorylates IKKbeta (Homo sapiens)


name: ATP + butanoate + CoA <=> AMP + butanoyl-CoA + diphosphate


name: CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 (Caenorhabditis elegans)


name: apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + ATP + biotin => AMP + diphosphate + H(+) + holo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)]


name: 2-oxoglutarate + N(omega)-methyl-L-arginyl-[protein] + O2 => CO2 + formaldehyde + L-arginyl-[protein] + succinate


name: The 60S subunit joins the translation initiation complex  (Drosophila melanogaster)


name: CUL5 mediates ubiquitination of ERBB2 (Caenorhabditis elegans)


name: 1-deoxysphinganine + a fatty acyl-CoA = CoA + H(+) + N-acyl-1-deoxysphinganine


name: Trans-homophilic interaction of PECAM-1 (Gallus gallus)


name: ADP + H(+) + O-(L-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein] => ADP-L-glycero-beta-D-manno-heptose + L-seryl-[protein]


name: PNPLA5 hydrolyzes TAG (Drosophila melanogaster)


name: CYP3A4 monooxygenates ATVL to 2-OH-ATVL (Sus scrofa)


name: (E)-cinnamate + ATP + CoA <=> (E)-cinnamoyl-CoA + AMP + diphosphate


name: 11-cis-retinol + a fatty acyl-CoA <=> 11-cis-retinyl ester + CoA


name: glycerol 3-phosphate + acyl-CoA => 1-acylglycerol 3-phosphate + CoASH [mitochondrial membrane-associated] (Mus musculus)


name: RHOBTB3 hydrolyzes ATP (Dictyostelium discoideum)


name: GRB2-1:SOS1 binds p-IRS1,p-IRS2 (Sus scrofa)


name: LDH tetramer oxidises LACT to PYR (Bos taurus)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Xenopus tropicalis)


name: PGG2 is reduced to PGH2 by PTGS1 (Sus scrofa)


name: H2O + N-octadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => (9Z)-octadecenoate + H(+) + N-octadecanoyl-sn-glycero-3-phospho-ethanolamine


name: beta-D-glucose + O2 <=> D-glucono-1,5-lactone + H2O2


name: PP2A methylation by LCMT1 (Drosophila melanogaster)


name: ADP + cholate(out) + H(+) + phosphate => ATP + cholate(in) + H2O


name: H(+) + NADPH + naphthalene-1,2-diol => (1R,2R)-1,2-dihydronaphthalene-1,2-diol + NADP(+)


name: Defective NEIL1 variants do not cleave Tg (Homo sapiens)


name: p-S225-SPHK1 localizes to cytosol (Rattus norvegicus)


name: NLRX1 binds CHUK:IKBKB:IKBKG (Homo sapiens)


name: CYP1A2 hydroxylates AFB1 to AFM1 (Sus scrofa)


name: 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: O2 + proatranorin IV + reduced [NADPH--hemoprotein reductase] <=> atranorin + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase]


name: biochanin A + 2 H(+) + NADPH => 2,3-dihydrobiochanin A + NADP(+)


name: (2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H(+) => (S)-4,5-dihydroxypentane-2,3-dione + ATP


name: ABL1 binds PPARG2 (Caenorhabditis elegans)


name: 2,6-dimethylheptanoate + CoA + H(+) => 2,6-dimethylheptanoyl-CoA + H2O


name: (3S,5R,6R)-3,5-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al + 2-cis,4-trans-xanthoxin => 9'-cis-neoxanthin + O2


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Caenorhabditis elegans)


name: a ganglioside GM1 (d18:1(4E)) + H2O <=> a ganglioside GM2 (d18:1(4E)) + D-galactose


name: L-homoserine => 2-aminobut-2-enoate + H2O


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Caenorhabditis elegans)


name: 2-hydroxyethane-1-sulfonate + FMNH2 + O2 => FMN + glycolaldehyde + 2 H(+) + H2O + sulfite


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid IVA => a 2-acyl-sn-glycero-3-phosphocholine + a lipid IVB


name: SMAD7 binds to SMURF2 (Drosophila melanogaster)


name: HCCS inserts heme into cytochrome c (Drosophila melanogaster)


name: Activation of p38 MAPK (Dictyostelium discoideum)


name: (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + chloride + FADH2 + O2 <=> (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O


name: TRAF6 is auto-ubiquitinated (Danio rerio)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Bos taurus)


name: 3-oxoeicosanoyl-CoA + CO2 + CoA => H(+) + malonyl-CoA + octadecanoyl-CoA


name: HSP90 binds TBK1 and IRF3 (Mus musculus)


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Saccharomyces cerevisiae)


name: a ubiquinone + H(+) + NADH <=> a ubiquinol + NAD(+)


name: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate (Dictyostelium discoideum)


name: H2O + N-acetyl-2,7-anhydro-alpha-neuraminate = N-acetyl-alpha-neuraminate


name: CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Sus scrofa)


name: p85 regulatory unit of PI3K binds p-6Y-SYK (Mus musculus)


name: cis-abienol + diphosphate => 8-hydroxycopalyl diphosphate


name: LTA4 is converted to LTC4 by LTC4S (Dictyostelium discoideum)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Xenopus tropicalis)


name: 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + O2 + reduced [NADPH--hemoprotein reductase] <=> 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + 2 H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate => ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine


name: Fibronectin degradation by CTSG (Bos taurus)


name: ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA (Dictyostelium discoideum)


name: luteolin + UDP-alpha-D-glucose => H(+) + isoorientin + UDP


name: ERBB4 binds NRGs or EGF-like ligands (Danio rerio)


name: acetyl-[citrate lyase ACP] + H2O => acetate + H(+) + holo-[citrate lyase ACP]


name: Autophagosome maturation (Gallus gallus)


name: SPHK2 binds SPHK2 inhibitors (Drosophila melanogaster)


name: IRAK2 induces TRAF6 oligomerization (Canis familiaris)


name: Dephosphorylation of phospho-Cdh1 (Bos taurus)


name: PGH2 is isomerised to PGD2 by HPGDS (Caenorhabditis elegans)


name: RNF144A polyubiquitinates PRKDC (Gallus gallus)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Sus scrofa)


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Xenopus tropicalis)


name: 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate


name: 5-oxo-L-proline(out) + 2 Na(+)(out) = 5-oxo-L-proline(in) + 2 Na(+)(in)


name: DNA polymerase epsilon binds at the origin (Mus musculus)


name: DHAP is converted to G3P by GPD1/GPD1L (Rattus norvegicus)


name: [thioredoxin]-dithiol + adenosine 5'-phosphosulfate => [thioredoxin]-disulfide + AMP + 2 H(+) + sulfite


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Rattus norvegicus)


name: Elongation Of The Telomeric Chromosome End (Sus scrofa)


name: (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B <=> aspoquinolone B


name: SUMOylation of HDAC2 with SUMO1 (Mus musculus)


name: SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Mus musculus)


name: CYP8B1 12-hydroxylates 4CHOL7aOLONE (Danio rerio)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 glutathione => (5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: AMOT proteins bind WWTR1 (TAZ) (Mus musculus)


name: Acyl Ghrelin and C-Ghrelin are secreted (Gallus gallus)


name: CCNK binds CDK12 (Drosophila melanogaster)


name: PALM-C36-ASGR1:PALM-C54,58-ASGR2 binds desialated glycoproteins (Danio rerio)


name: Dynamin is recruited to the gap junction plaque (Bos taurus)


name: Activated FGFR1:p-FRS binds GRB2:SOS1 (Bos taurus)


name: ADP + H(+) + thiamine diphosphate = adenosine thiamine triphosphate + phosphate


name: 3 H2O + N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + 2 NAD(+) => H(+) + N(omega)-methyl-L-arginine + 2 NADH + 3 O2


name: PARVB/Affixin interacts with alpha PIX (Homo sapiens)


name: Recruitment of PAK to the membrane by binding active RAC1 (Xenopus tropicalis)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Mus musculus)


name: 3-oxoisoapionate + H(+) <=> CO2 + L-erythrulose


name: maltose + H2O => 2 D-glucose (maltase-glucoamylase) (Mus musculus)


name: Aquaporins passively transport glycerol into cells (Saccharomyces cerevisiae)


name: 3-hydroxyphenylacetate + H(+) + NADPH + O2 <=> H2O + homogentisate + NADP(+)


name: ATP + H2O + N-acetyl-L-glutamate(in) <=> ADP + H(+) + N-acetyl-L-glutamate(out) + phosphate


name: ERK1/2/5 activate RSK1/2/3 (Caenorhabditis elegans)


name: Exocytosis of platelet alpha granule contents (Mus musculus)


name: AH2 + NH4(+) + pyruvate => A + D-alanine + H2O


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Schizosaccharomyces pombe)


name: Hikeshi binds HSP70s:ATP (Canis familiaris)


name: E protein gets palmitoylated (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + sn-glycerol 3-phosphocholine <=> (9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + CoA


name: 2 H(+) + 3 H2O + hydrogen sulfide + 3 oxidized coenzyme F420-(gamma-L-Glu)(n) => 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Schizosaccharomyces pombe)


name: 3,5,3'-triiodothyronine + PAPS => 3,5,3'-triiodothyronine 4-sulfate + PAP (Mus musculus)


name: SLC25A1 exchanges CIT and MAL (Rattus norvegicus)


name: (3S)-hydroxytetradecanoyl-CoA + NAD(+) = 3-oxotetradecanoyl-CoA + H(+) + NADH


name: acetyl-CoA + H(+) + 3 malonyl-CoA + S-adenosyl-L-methionine = 5-methylorsellinate + 3 CO2 + 4 CoA + S-adenosyl-L-homocysteine


name: H(+) + hexadecanoyl-[ACP] + malonyl-[ACP] = 3-oxooctadecanoyl-[ACP] + CO2 + holo-[ACP]


name: C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + H2O => C-terminal L-alpha-aminoacyl-[tubulin] + L-glutamate


name: H(+) + H2O + oryzalexin E + oxidized [NADPH--hemoprotein reductase] => ent-sandaracopimaradien-3beta-ol + O2 + reduced [NADPH--hemoprotein reductase]


name: PIAS1,2-1 SUMOylates AR with SUMO1 (Gallus gallus)


name: 3 hydrogencarbonate(in) + Na(+)(in) => 3 hydrogencarbonate(out) + Na(+)(out)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Canis familiaris)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: 1-acyl LPA is acylated to PA by AGPAT (LPAAT) (Dictyostelium discoideum)


name: Activated FGFR1 phosphorylates PLCG1 (Canis familiaris)


name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Sus scrofa)


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Canis familiaris)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Drosophila melanogaster)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Schizosaccharomyces pombe)


name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Schizosaccharomyces pombe)


name: dihydrocurcumin + NADP(+) <=> curcumin + H(+) + NADPH


name: Active p38 MAPK phosphorylates MAPKAPK5 (Gallus gallus)


name: H2O + streptomycin 6-phosphate => phosphate + streptomycin


name: PDPK1 phosphorylates PKN1,2,3 (Danio rerio)


name: bradykinin + H2O <=> bradykinin(1-7) + L-Phe-L-Arg


name: (Z)-2-methylaminoacrylate + CO2 + NH4(+) => (Z)-2-methylureidoacrylate + H(+) + H2O


name: NUDT18 hydrolyses 8-oxo-dADP to 8-oxo-dAMP (Mus musculus)


name: ECHS1 hydrates methacrylyl-CoA (Bos taurus)


name: OSBP exchanges 25OH-CHOL with PI4P from ER membrane to Golgi membrane (Rattus norvegicus)


name: Endosome acidification (Dictyostelium discoideum)


name: a ganglioside Fuc-GM1 + UDP-alpha-D-galactose = ganglioside Fuc(Gal)-GM1 + H(+) + UDP


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Xenopus tropicalis)


name: an NDP-alpha-D-glucose + D-glucose = a ribonucleoside 5'-diphosphate + alpha,alpha-trehalose + H(+)


name: 2 H2O + 4 oxidized [4Fe-4S]-[ferredoxin] + taurine <=> glycine + 6 H(+) + 4 reduced [4Fe-4S]-[ferredoxin] + sulfite


name: 19-(4-hydroxyphenyl)nonadecanoate + ATP + holo-[(phenol)carboxyphthiodiolenone synthase] => 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base = a 1,2-diacyl-sn-glycerol + an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base


name: CYP3A7 can 6beta-hydroxylate testosterone (Rattus norvegicus)


name: D-glucono-1,5-lactone + H2O2 => beta-D-glucose + O2


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Schizosaccharomyces pombe)


name: H2O + N(6)-propanoyl-L-lysyl-[protein] + NAD(+) <=> 3''-O-propanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: MTMR14, MTMR3 dephosphorylate PI3P (Canis familiaris)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Xenopus tropicalis)


name: A + H2O + prostaglandin H2 => AH2 + prostaglandin G2


name: WWTR1 (TAZ), TBX5, and PCAF form a complex (Caenorhabditis elegans)


name: TGFBR3(784-851) degradation (Homo sapiens)


name: Activation of TAK1 complex bound to pUb-TRAF6 (Rattus norvegicus)


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Drosophila melanogaster)


name: CYP3A4,5 oxidise AFB1 to AFXBO (Mus musculus)


name: Unwinding DNA for the nascent transcript (Xenopus tropicalis)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H(+)


name: ITPA hydrolyses XTP to XMP (Drosophila melanogaster)


name: isoliquiritigenin + S-adenosyl-L-methionine => 2'-O-methylisoliquiritigenin + H(+) + S-adenosyl-L-homocysteine


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Schizosaccharomyces pombe)


name: H(+)(in) + L-glutamate(in) <=> H(+)(out) + L-glutamate(out)


name: 1-heptadecanoyl-2-octadecanoyl-sn-glycero-3-phosphate + CoA => 1-heptadecanoyl-sn-glycero-3-phosphate + octadecanoyl-CoA


name: PolyUb-Misfolded proteins bind vimentin to form aggresome (Canis familiaris)


name: Active FLT3:GRB2:p-GAB2:PIK3R1 binds PIK3CA (Mus musculus)


name: H2O + rhodomycin D = 10-carboxy-13-deoxycarminomycin + H(+) + methanol


name: Inactivation of over-expressed wild type EGFR by Cetuximab recombinant antibody (Homo sapiens)


name: ATG12 forms a thioester bond with ATG7 dimer (Schizosaccharomyces pombe)


name: (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate => 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: 26Sproteasome degrades K48polyUb-NIK (Mus musculus)


name: MMAB adenosylates cob(I)alamin (Dictyostelium discoideum)


name: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate => N-(5-phospho-beta-D-ribosyl)anthranilate


name: 2-oxoglutarate + L-histidine => 3-(imidazol-5-yl)pyruvate + L-glutamate


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA


name: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + phosphate


name: Activation of Ca impermeable AMPA receptors (Sus scrofa)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(ribonucleotide) in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + H(+) + S-adenosyl-L-homocysteine


name: p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP (Homo sapiens)


name: Formation of PRC2-EZH2 complex (Mus musculus)


name: 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + CoA => a long-chain fatty acyl-CoA + alpha,alpha-trehalose


name: UDP-glucose transmembrane transporter activity


name: glycine betaine(out) + Na(+)(out) <=> glycine betaine(in) + Na(+)(in)


name: OSM,LIF,CTF1 receptor complex binds gp130 (Sus scrofa)


name: 5-aminopentanamide + H2O => 5-aminopentanoate + NH4(+)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Bos taurus)


name: CAD hexamer transforms L-Gln to CAP (Saccharomyces cerevisiae)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Gallus gallus)


name: Expression of SOX9 in testis differentiation (Homo sapiens)


name: FN1 binds Collagen types I-V, VII (Mus musculus)


name: ATP + UTP <=> 3',3'-cUAMP + 2 diphosphate


name: 2-hydroxyisobutanoyl-CoA <=> acetone + formyl-CoA


name: 2-methyl-6-phytyl-1,4-benzene-1,4-diol + S-adenosyl-L-methionine => 2,3-dimethyl-6-phytylbenzene-1,4-diol + H(+) + S-adenosyl-L-homocysteine


name: D-glucose 6-phosphate + TDP-alpha-D-glucose <=> alpha,alpha-trehalose 6-phosphate + H(+) + TDP


name: D-galactose + NAD(+) <=> D-galactono-1,4-lactone + H(+) + NADH


name: (9Z)-octadecenoyl-CoA + 1,2-di-(9Z-octadecenoyl)-sn-glycerol => 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA


name: PG is hydrolysed to 2-acyl LPG by PLA2G4B (IM) (Sus scrofa)


name: L-cysteinyl-[protein] + octadecanoyl-CoA => CoA + S-octadecanoyl-L-cysteinyl-[protein]


name: RUNX1 and ELF1 bind the IL3 gene promoter (Homo sapiens)


name: 17beta-hydroxy-5alpha-androstan-3-one + UDP-alpha-D-glucuronate => 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + H(+) + UDP


name: 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate


name: RUNX1 binds PAX5 (BSAP) (Canis familiaris)


name: MITF-M-dependent ATP6V0E1 gene expression (Homo sapiens)


name: Phosphopantetheine conjugation of the ACP domain of FAS (Sus scrofa)


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP


name: ATP2B4 binds to NOS1, inhibiting it (Bos taurus)


name: CDK4 inhibitors bind CDK4 (Xenopus tropicalis)


name: 2-hydroxyhexacosanoyl-CoA + sphinganine = CoA + H(+) + N-(2-hydroxyhexacosanoyl)-sphinganine


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-hexadecanoylethanolamine => H2O + N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: desmethylxanthohumol + diphosphate => 2',4,4',6'-tetrahydroxychalcone + dimethylallyl diphosphate


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Bos taurus)


name: 2 H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UMP => H2O + UDP-N-acetyl-alpha-D-glucosamine


name: p-CBL:GRB2 binds p-FRS2:activated FGFR2 (Mus musculus)


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Rattus norvegicus)


name: Rheb in the MTORC1 complex hydrolyses GTP (Caenorhabditis elegans)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Xenopus tropicalis)


name: 2 a thiol + L-cysteinyl-[sulfatase] + O2 <=> 3-oxo-L-alanyl-[sulfatase] + an organic disulfide + H(+) + H2O + hydrogen sulfide


name: H2O + O2 + spermidine = 4-aminobutanal + H2O2 + propane-1,3-diamine


name: a short-chain fatty acyl-CoA + AMP + diphosphate => a short-chain fatty acid + ATP + CoA


name: glycine + hexacosanoate = H2O + N-hexacosanoylglycine


name: L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) + N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine


name: "type II protein arginine methyltransferase"


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Sus scrofa)


name: MRN bound to shortened telomeres activates ATM (Schizosaccharomyces pombe)


name: O2 + tetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O2


name: Formation of translation initiation complexes containing mRNA that does not circularize (Drosophila melanogaster)


name: 3-hydroxypropanal + H2O + NAD(+) => 3-hydroxypropanoate + 2 H(+) + NADH


name: L-threo-3-phenylserine => benzaldehyde + glycine


name: p-S92,203-BRF1 binds 14-3-3 (Homo sapiens)


name: prostaglandin E1 <=> H2O + prostaglandin A1


name: 3,6-anhydro-alpha-L-galactopyranose + H2O + NADP(+) <=> 3,6-anhydro-L-galactonate + 2 H(+) + NADPH


name: Inactivation of Rho-GTP by p190RhoGAP (Sus scrofa)


name: AKT phosphorylates caspase-9 (Rattus norvegicus)


name: 2 Na(+)(out) + thymidine(out) <=> 2 Na(+)(in) + thymidine(in)


name: Prolyl 3-hydroxylases:Fe2+:3,4-Hyp collagen propeptides dissociates (Homo sapiens)


name: SRD5A1 dehydrogenates TEST to DHTEST (Danio rerio)


name: CHIA hydrolyses chitin (Rattus norvegicus)


name: Neuropeptide Y receptors can bind neuropeptide Y-related peptides (Mus musculus)


name: Exportin-5 recognizes 3' overhang of pre-miRNA  (Homo sapiens)


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin (Xenopus tropicalis)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Caenorhabditis elegans)


name: transforming growth factor beta receptor activity, type I


name: ASA- acetylates PTGS2 (Xenopus tropicalis)


name: 25-hydroxyvitamin D2 + 2 H(+) + O2 + 2 reduced [adrenodoxin] <=> 1alpha,25-dihydroxyvitamin D2 + H2O + 2 oxidized [adrenodoxin]


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Sus scrofa)


name: H(+) + N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine => N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + O2 => N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-taurine


name: Export of peptide loaded MHC class I complex to PM (Sus scrofa)


name: an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + H2O => 1-methyladenine + a 2'-deoxyribose 5'-phosphate in double-stranded DNA + H(+)


name: (4E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + H(+) + S-adenosyl-L-homocysteine => (4E,8E)-10-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-4,8-dienoate + S-adenosyl-L-methionine


name: IRE1 dimer autophosphorylates (Bos taurus)


name: 3,4-dihydroxy-5-all-trans-decaprenylbenzoate + S-adenosyl-L-methionine => 3-methoxy-4-hydroxy-5-all-trans-decaprenylbenzoate + H(+) + S-adenosyl-L-homocysteine


name: 17alpha-estradiol + UDP-alpha-D-glucuronate = 17alpha-estradiol 3-O-(beta-D-glucuronate) + H(+) + UDP


name: Association of procollagen type XVI (Canis familiaris)


name: ESR1 binds ESR1 antagonists (Xenopus tropicalis)


name: PIAS2,3,4 SUMOylate RORA with SUMO2 (Bos taurus)


name: peregrinol diphosphate <=> diphosphate + labd-13(16),14-diene-9-ol


name: H2O + N-eicosanoyl-sphing-4-enine = eicosanoate + sphing-4-enine


name: kaempferol + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + quercetin


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Sus scrofa)


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Mus musculus)


name: ADRM1 binds 26S proteasome (Mus musculus)


name: Na(+)(out) + propanoate(out) => Na(+)(in) + propanoate(in)


name: Interleukin-35 translocates from the ER lumen to the extracellular region (Homo sapiens)


name: p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Saccharomyces cerevisiae)


name: Hh C-terminal fragments are degraded by the proteasome (Xenopus tropicalis)


name: Phosphorylation of cohesin by PLK1 at centromeres (Rattus norvegicus)


name: SLC25A11 exchanges malate and alpha-ketoglutarate (2-oxoglutarate) across the inner mitochondrial membrane (Plasmodium falciparum)


name: H2O + L-lysine + NADP(+) = (S)-2-amino-6-oxohexanoate + H(+) + NADPH + NH4(+)


name: Linkage of L1 with treadmilling F-actin (Homo sapiens)


name: CDP-Cho and DAG are converted to PC by CEPT1 at the ER membrane (Xenopus tropicalis)


name: 2'-deoxyguanosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + guanine


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Rattus norvegicus)


name: a (2S)-2-hydroxycarboxylate + a halide anion + H(+) => an (S)-2-haloacid + H2O


name: 1D-myo-inositol 1,2,6-trisphosphate + H2O = 1D-myo-inositol 1,2-bisphosphate + phosphate


name: 10-hydroxy-alpha-humulene + NAD(+) = H(+) + NADH + zerumbone


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Schizosaccharomyces pombe)


name: SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) (Canis familiaris)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Mus musculus)


name: oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor


name: 2-aminobenzoyl-AMP + CoA => AMP + anthraniloyl-CoA + H(+)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Gallus gallus)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Gallus gallus)


name: H(+) + keto-D-tagatose + NADH => galactitol + NAD(+)


name: Cleavage of uracil by SMUG1 glycosylase (Drosophila melanogaster)


name: TPX2 promotes AURKA autophosphorylation (Xenopus tropicalis)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Mus musculus)


name: NQO2:FAD dimer reduces quinones to hydroquinones (Xenopus tropicalis)


name: 2 adenosylcob(III)inamide + 2 diphosphate + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 phosphate => 2 ATP + 2 cob(II)inamide + 2 H2O + reduced [electron-transfer flavoprotein]


name: dUTP + H2O => dUMP + pyrophosphate (Schizosaccharomyces pombe)


name: malonate(out) + sulfate(in) => malonate(in) + sulfate(out)


name: a 3'-end uridylyl-adenosine-RNA => a 3'-end 2',3'-cyclophospho-uridine-RNA + adenosine


name: H(+) + keto-D-fructose + NADH <=> D-sorbitol + NAD(+)


name: a pyrimidine ribonucleoside 5'-phosphate + H2O => a pyrimidine nucleobase + D-ribose 5-phosphate


name: ATP + H(+) + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide => 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + diphosphate


name: TPX2 binds AURKA at centrosomes (Mus musculus)


name: (9Z)-octadecenoyl-CoA + 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol => 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA


name: H2O + xanthurenate => 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate


name: ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 (Homo sapiens)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Mus musculus)


name: TP73 tetramer translocates to the nucleus (Xenopus tropicalis)


name: AcK685 pY705,S727 STAT3 binds the MIR21 gene (Homo sapiens)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Mus musculus)


name: TGFBR2 phosphorylates TGFBR1 (Gallus gallus)


name: SIRT3 deacetylates AcK-IDH2 dimer (Canis familiaris)


name: FKBP1A binds tacrolimus (Rattus norvegicus)


name: Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Drosophila melanogaster)


name: acetoacetyl-CoA + H(+) + NADH => (3S)-3-hydroxybutanoyl-CoA + NAD(+)


name: a uridine in mRNA + S-adenosyl-L-methionine <=> a 5-methyluridine in mRNA + H(+) + S-adenosyl-L-homocysteine


name: ATP + N-acetyl-alpha-D-galactosamine => ADP + H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate


name: 2 (S)-methylmalonyl-CoA + docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 10 H(+) + 3 malonyl-CoA + 5 NADPH => C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 CoA + 2 H2O + 5 NADP(+)


name: SIRT5 deacetylates Cytochrome C (Dictyostelium discoideum)


name: RHOU binds effectors at the plasma membrane (Mus musculus)


name: Interaction of other tyrosine kinases with p-KIT (Canis familiaris)


name: Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes (Caenorhabditis elegans)


name: Coumarin is 7-hydroxylated by CYP2A13 (Drosophila melanogaster)


name: HDAC4 SUMOylates NR1H3 (LXRalpha) with SUMO2,3 (Homo sapiens)


name: H2O + N-acyl-15-methylhexadecasphing-4-enine => 15-methylhexadecasphing-4-enine + a fatty acid


name: an N-acetyl-alpha-D-galactosaminyl derivative + UDP-alpha-D-galactose => a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + H(+) + UDP


name: Intraphagosomal pH is lowered to 5 by V-ATPase (Danio rerio)


name: dichloromethane + H2O = 2 chloride + formaldehyde + 2 H(+)


name: 3-oxotetradecanoyl-[ACP] + H(+) + NADPH <=> (3R)-hydroxytetradecanoyl-[ACP] + NADP(+)


name: heptadecasphing-4-enine + octadecanoyl-CoA <=> CoA + H(+) + N-octadecanoyl-heptadecasphing-4-enine


name: CTP(out) + dUMP(in) = CTP(in) + dUMP(out)


name: (R)-glycerate + NADP(+) <=> 2-hydroxy-3-oxopropanoate + H(+) + NADPH


name: USP16,USP21 deubiquitinate Histone H2A (Dictyostelium discoideum)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Gallus gallus)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Homo sapiens)


name: 7alpha-hydroxycholesterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => cholesterol + O2 + reduced [NADPH--hemoprotein reductase]


name: p-Y7-CLEC1B dimer:PDPN binds SYK (Canis familiaris)


name: PSPN binds RET:GFRA4 (Rattus norvegicus)


name: 5-dehydro-D-fructose + AH2 => A + keto-L-sorbose


name: RHOV binds GTP (Dictyostelium discoideum)


name: PIAS2,3,4 SUMOylate RORA with SUMO2 (Sus scrofa)


name: P4HB mediates disulfide bond formation in Proinsulin (Gallus gallus)


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Saccharomyces cerevisiae)


name: 2 3-phenylpyruvate + H(+) <=> H2O + phenguignardate


name: GPX4-2 reduces 17(S)-Hp-DHA to 17(S)-HDHA (Homo sapiens)


name: a D-threo-aldose + NAD(+) <=> a D-threo-aldono-1,5-lactone + H(+) + NADH


name: MAPK4,6 translocate to nucleus (Sus scrofa)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Gallus gallus)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Bos taurus)


name: dihydrobunolol + NADP(+) => bunolol + H(+) + NADPH


name: ALOX5 is phosphorylated by MAPKAP2 (Danio rerio)


name: Phosphorylation of CRMPs by Cdk5 (Gallus gallus)


name: USP19 binds HIF1A,BIRC2,BIRC3 (Mus musculus)


name: acetyl-CoA + chloramphenicol <=> chloramphenicol 3-acetate + CoA


name: COQ3 methylates DHDB (Schizosaccharomyces pombe)


name: SUMOylation of DNMT3B with SUMO1 (Danio rerio)


name: SLC4A5,7,9 cotransport Na+ with 3HCO3- (Gallus gallus)


name: ATP + glycocholate(in) + H2O => ADP + glycocholate(out) + H(+) + phosphate


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Mus musculus)


name: 2-oxoglutarate + gibberellin A24 + O2 <=> CO2 + gibberellin A25 + H(+) + succinate


name: ADP + H(+) + valienone 7-phosphate => ATP + valienone


name: MMP14 (MT1-MMP) binds TIMP2 (Bos taurus)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Xenopus tropicalis)


name: (9Z)-octadecenoyl-CoA + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: LIPA hydrolyses sterol esters to sterols and fatty acids (Bos taurus)


name: Activated FGFR3 phosphorylates FRS2 (Mus musculus)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAA (Plasmodium falciparum)


name: beta-D-glucose 6-phosphate + hydroquinone => arbutin 6-phosphate + H2O


name: IDUA hydrolyses Heparan sulfate chain(6) (Rattus norvegicus)


name: POM121 binds the Nup107-Nup160 complex (Canis familiaris)


name: Cleavage of thymine by TDG glycosylase (Gallus gallus)


name: L-arginyl-[protein] + methylglyoxal => N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein]


name: E2F6:TFDP1 binds to MGA:MAX (Homo sapiens)


name: H2O + N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + NAD(+) => (8S)-8-amino-7-oxononanoate + H(+) + L-lysyl-[protein] + NADH


name: diphosphate + GDP-D-glycero-alpha-D-manno-heptose => D-glycero-alpha-D-manno-heptose 1-phosphate + GTP + H(+)


name: CALR, TAP, TAPBP dissociate from SEC22B:STX4 (Rattus norvegicus)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Mus musculus)


name: ST3GAL5 transfers NeuNAc to ceramides (Danio rerio)


name: DHNTP is dephosphorylated by PTPS to PTHP (Sus scrofa)


name: Formation of NR-MED1 Coactivator Complex (Sus scrofa)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + H(+) + NADPH = 11beta,17beta-dihydroxyandrost-4-ene-3-one + NADP(+)


name: KDM6A, KDM6B, KDM7A demethylate Me3K28-histone H3 (Mus musculus)


name: PTPN7 dephosphorylates p-T,Y-MAPKs (Drosophila melanogaster)


name: Expression of Phosphomevalonate Kinase (PMVK) (Homo sapiens)


name: 2-hydroxyheptadecanoyl-CoA + CO2 + succinate => 2-oxoglutarate + heptadecanoyl-CoA + O2


name: G protein-coupled receptor kinase activity


name: Autophosphorylation of PAK (Homo sapiens)


name: CD isomers transform to BT, BTCA, BZ, ODHBT (Homo sapiens)


name: diphosphate + miltiradiene => (+)-copalyl diphosphate


name: ATP + deamido-NAD(+) + H2O + L-glutamine => AMP + diphosphate + H(+) + L-glutamate + NAD(+)


name: Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Homo sapiens)


name: NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP (Sus scrofa)


name: TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation (Gallus gallus)


name: PKG1 phosphorylates IRAG:IP3R1 inhibiting IP3-stimulated Ca2+ release (Mus musculus)


name: acetate transmembrane transporter activity


name: 1-tetradecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O <=> (9Z,12Z)-octadecadienoate + 1-tetradecanoyl-sn-glycero-3-phosphocholine + H(+)


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Canis familiaris)


name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)


name: 15,16-epoxydolabrene + O2 + reduced [NADPH--hemoprotein reductase] => 3beta-hydroxy-15,16-epoxydolabrene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Oxidative damage to the AP site (Canis familiaris)


name: ALOX15 oxidises 18(R)-HEPE to 18(R)-RvE3 (Canis familiaris)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Homo sapiens)


name: H2O(out) + nitrite(out) + ubiquinone-8(in) => nitrate(out) + ubiquinol-8(in)


name: 1-hexadecanoyl-sn-glycero-2,3-cyclic phosphate + choline => 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: ATM binds PEX5 (Dictyostelium discoideum)


name: (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2


name: Proglucagon translocates from the ER Lumen to secretory granules (Gallus gallus)


name: Recruitment of CBL to KIT (Caenorhabditis elegans)


name: PKA/PKG phosphorylate Rap1GAP2 (Mus musculus)


name: Arachidonate is oxidised to PGG2 by PTGS1 (Mus musculus)


name: a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GD1alpha (d18:1(4E)) + CMP + H(+)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 <=> (13S)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O


name: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate => 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+)


name: a 3-oxo-Delta(1)-steroid + H2O = a 1-hydroxy-3-oxo steroid


name: 4-hydroxybenzoate(in) + H(+)(out) <=> 4-hydroxybenzoate(out) + H(+)(in)


name: (2Z,6Z)-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + nerylneryl diphosphate


name: CYP17A1 cleaves 17aHPROG to ANDST (Danio rerio)


name: HSD17B3-like proteins reducde ANDST to TEST (Homo sapiens)


name: PAQR3 binds inactive RAFs (Drosophila melanogaster)


name: factor VII -> factor VIIa (Xenopus tropicalis)


name: p-Y-STAT3 binds p-STAT5 (Canis familiaris)


name: AFG3L2 binds mitochondrial matrix proteins (Plasmodium falciparum)


name: Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + N-(2,3-dihydroxybenzoyl)-L-serine => Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+) + H2O


name: H2O + indole-3-carbaldehyde + O2 => H(+) + H2O2 + indole-3-carboxylate


name: HIF1A,EPAS1 promote PTK6 gene expression (Homo sapiens)


name: AKT1 E17K mutant translocates to the nucleus (Homo sapiens)


name: CYP3A4 can N-demethylate loperamide (Sus scrofa)


name: dUTP + H2O => dUMP + pyrophosphate (Caenorhabditis elegans)


name: Formation of FACT complex (Rattus norvegicus)


name: TRAF2,6 ubiquitinates NLRC5 (Bos taurus)


name: RGGT:CHM binds RABs (Plasmodium falciparum)


name: ATP + H2O + itraconazole(in) <=> ADP + H(+) + itraconazole(out) + phosphate


name: 1D-myo-inositol 1,3-bisphosphate + H2O => 1D-myo-inositol 1-phosphate + phosphate


name: N-formimidoylglycine => H2O + imidazol-4-one


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Bos taurus)


name: Pol II elongation complex moves on the template as transcript elongates (Gallus gallus)


name: DNA nucleases unhook the interstrand crosslink (ICL) (Homo sapiens)


name: a dicarboxylate(in) + prostaglandin F2alpha(out) = a dicarboxylate(out) + prostaglandin F2alpha(in)


name: PKA/PKG phosphorylate Rap1GAP2 (Caenorhabditis elegans)