name: RNF8 binds phosphorylated MDC1 at DNA DSBs (Gallus gallus)


name: H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sphing-4-enine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + sphing-4-enine


name: ATP + Co(2+)(out) + H2O => ADP + Co(2+)(in) + H(+) + phosphate


name: 23S rRNA pseudouridine(955/2504/2580) synthase activity


name: all-trans-zeaxanthin + H2O + L-dehydroascorbate => all-trans-antheraxanthin + L-ascorbate


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Bos taurus)


name: a quinone + butan-1-ol => a quinol + butanal


name: SMURF2 ubiquitinates SMAD2 (Drosophila melanogaster)


name: GLI2,3 are degraded by the proteasome (Danio rerio)


name: CYP11A1 cleaves 20a,22b-DHCHOL (Rattus norvegicus)


name: PRODH oxidises L-Pro to 1PYR-5COOH (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) => 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + CoA


name: P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Caenorhabditis elegans)


name: diphosphate + Mo-molybdopterin cytosine dinucleotide => CTP + H(+) + Mo-molybdopterin


name: 3-methyl-2-oxobutanoate + formaldehyde => 2-dehydropantoate


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Bos taurus)


name: glutaryl-CoA + H2O = CoA + glutarate + H(+)


name: HILPDA binds lipid droplets (Mus musculus)


name: Activation of IKK complex (Mus musculus)


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Mus musculus)


name: L-allo-threonine => acetaldehyde + glycine


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Homo sapiens)


name: AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)


name: (8S)-8-amino-7-oxononanoate + CO2 + L-lysyl-[protein] <=> (7R,8S)-8-amino-7-(carboxyamino)nonanoate + (S)-2-amino-6-oxohexanoyl-[protein] + 2 H(+)


name: 4alpha-hydroxymethylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-methylzymosterol + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Homo sapiens)


name: 3-oxopropanoate + H(+) + H2O2 + nitrite => H2O + O2 + propionate 3-nitronate


name: (9Z)-octadecenoate + ATP + CoA <=> (9Z)-octadecenoyl-CoA + AMP + diphosphate


name: Phosphorylation of Platelet Sec-1 (Saccharomyces cerevisiae)


name: ALDH8A1 oxidises 9cRAL to 9cRA (Homo sapiens)


name: (5Z,8Z)-eicosadienoate + O2 => (5S)-hydroperoxy-(6E,8Z)-eicosadienoate


name: The SMAD2/3:SMAD4 complex transfers to the nucleus (Sus scrofa)


name: USP30 deubiquitinates ATM dimer:Ub-p-PEX5 (Bos taurus)


name: a 5'-end L-tyrosylphosphate-2'-deoxynucleoside-DNA + H2O = a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+) + L-tyrosine


name: p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Xenopus tropicalis)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate <=> 2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2 <=> a 1-acyl-2-(15-hydroperoxy-5Z,8Z,11Z,13E-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)


name: H(+) + NADH + O2 + theobromine => 7-methylxanthine + formaldehyde + H2O + NAD(+)


name: AhpC reduces peroxidated lipids (Homo sapiens)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Schizosaccharomyces pombe)


name: Synthesis of PIP3 from PIP2 by PI3K (Rattus norvegicus)


name: (S)-beta-macrocarpene + O2 + reduced [NADPH--hemoprotein reductase] = [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase] + thymol => gamma-terpinene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: Association of procollagen type XX (Sus scrofa)


name: Phosphorylation of Y1229 in L1 (Homo sapiens)


name: (3S)-hydroxyhexadecanoyl-CoA <=> (2E)-hexadecenoyl-CoA + H2O


name: AURKA phosphorylates PLK1 (Xenopus tropicalis)


name: 2-aryl-2-methylmalonate + H(+) => 2-arylpropionate + CO2


name: 2,5-hexanedione + 2 H(+) + 2 NADPH <=> (2R,5R)-hexanediol + 2 NADP(+)


name: Hypochlorous acid (HOCL) reacts with Lys residue to form Lys-monochloramine (Homo sapiens)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Rattus norvegicus)


name: ATP(in) + CoA(in) + decanoate(out) + H(+)(out) <=> AMP(in) + decanoyl-CoA(in) + diphosphate(in) + H(+)(in)


name: Interaction of Tie2 and Shp2 (Mus musculus)


name: beta-D-apiofuranosyl-(1->6)-D-glucopyranose + dalpatein + H(+) => dalpatein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O


name: D-glucose(out) + Na(+)(out) <=> D-glucose(in) + Na(+)(in)


name: Recruitment and activation of Chk1 (Drosophila melanogaster)


name: MAOA:FAD oxidatively deaminates of 5HT (Mus musculus)


name: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol (Bos taurus)


name: chlorophyllide a + NADP(+) <=> 3,8-divinyl chlorophyllide a + H(+) + NADPH


name: ITP(out) + UTP(in) <=> ITP(in) + UTP(out)


name: Release of SEPT4 from mitochondria (Bos taurus)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)


name: Autocatalytic phosphorylation of Klotho-bound FGFR1c (Gallus gallus)


name: p-STAT3 dissociates from IL24:IL22RA1:p‑JAK1:IL20RB:p‑STAT3 (Bos taurus)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Dictyostelium discoideum)


name: 4-methylsulfanyl-2-oxobutanoate + L-kynurenine <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine


name: dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2 S-adenosyl-L-methionine <=> dTDP-alpha-D-desosamine + 2 H(+) + 2 S-adenosyl-L-homocysteine


name: PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser (Homo sapiens)


name: N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine = (9Z,12Z,15Z)-octadecatrienamide + glyoxylate


name: SRD5A3 dehydrogenates TEST to DHTEST (Xenopus tropicalis)


name: SUMOylation of RAD52 with SUMO1 (Sus scrofa)


name: L-pentahomomethionine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-8-(methylsulfanyl)octanal oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde => 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O


name: TYRP1 oxidises DHICA to IQCA (Dictyostelium discoideum)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA


name: Interaction of integrin alphaXbeta2 with fibrin (Rattus norvegicus)


name: 5,10-dihydrophenazine 1-carboxylate + O2 => H2O2 + phenazine-1-carboxylate


name: USP2 deubiquitinates MDM2,MDM4 (Homo sapiens)


name: (d)ADP + ADP <=> (d)AMP + ATP (AK1) (Rattus norvegicus)


name: acetoacetyl-CoA + ATP + L-isoleucine = AMP + CoA + diphosphate + 2 H(+) + tenuazonic acid


name: 2-oxobutanoate + CoA + NAD(+) <=> CO2 + NADH + propanoyl-CoA


name: 2-oxoglutarate + L-isoleucine + O2 = (4S)-4-hydroxy-L-isoleucine + CO2 + succinate


name: (2Z)-2-hydroxypenta-2,4-dienoate + H2O => (S)-4-hydroxy-2-oxopentanoate


name: (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate = 4-hydroxybutylnitrile + sulfate + sulfur


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Saccharomyces cerevisiae)


name: TP53 binds the complex of JMY, EP300 and TTC5 (Canis familiaris)


name: CDC42 GEFs activate CDC42 (Rattus norvegicus)


name: SMAC binds XIAP:Caspase-7 (Xenopus tropicalis)


name: RHO1:GDP complex dissociates from RHOGAPP190 (Drosophila melanogaster)


name: a short-chain fatty aldehyde + H2O + NAD(+) <=> a short-chain fatty acid + 2 H(+) + NADH


name: MET phosphorylates GAB1 (Rattus norvegicus)


name: Phosphorylation of RAF (Drosophila melanogaster)


name: urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR (Sus scrofa)


name: PLK1 phosphorylates FIRMM at S744 (Gallus gallus)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine <=> 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: Translocation of p27 to the nucleoplasm (Homo sapiens)


name: USP24 deubiquitinates DDB2 (Gallus gallus)


name: long-chain fatty acid transmembrane transporter activity


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + ATP <=> 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+)


name: (1'S)-averantin + NADP(+) = H(+) + NADPH + norsolorinic acid


name: G protein-coupled adenosine receptor activity


name: benzaldehyde + hydrogen cyanide = (S)-mandelonitrile


name: H2O + NADP(+) + rifamycin SV para-naphthoquinone carboxamide => NADPH + O2 + rifamycin SV


name: chloride(out) + L-asparagine(out) + 2 Na(+)(out) = chloride(in) + L-asparagine(in) + 2 Na(+)(in)


name: 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2 => (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+)


name: Interaction of SOS with GRB2 bound to FADK1 (Sus scrofa)


name: (2S,4S)-4-hydroxy-4-methylglutamate + ATP + 11 H(+) + 8 malonyl-CoA + 8 NADPH + 3 S-adenosyl-L-methionine => (2S)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 8 CO2 + 8 CoA + diphosphate + 6 H2O + 8 NADP(+) + 3 S-adenosyl-L-homocysteine


name: a ribonucleoside 5'-triphosphate + AMP <=> a ribonucleoside 5'-diphosphate + ADP


name: ARFGAPs stimulate ARF GTPase activity (Gallus gallus)


name: 3-dehydro-15-methylhexadecasphinganine + CO2 + CoA => H(+) + isopentadecanoyl-CoA + L-serine


name: AH2 + gluconapin + O2 <=> A + H2O + progoitrin


name: histone lactyltransferase (CoA-dependent) activity


name: ESD dimer hydrolyses S-FGSH to GSH (Drosophila melanogaster)


name: an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Mus musculus)


name: uridine(2605) in 23S rRNA <=> pseudouridine(2605) in 23S rRNA


name: PIAS1 SUMOylates SP3 with SUMO1 (Sus scrofa)


name: NTF3-bound NTRK2 dimers trans-autophosphorylate (Homo sapiens)


name: H2O + NAD(+) + vanillin <=> 2 H(+) + NADH + vanillate


name: Activation of TAK1 complex bound to activated TLR4 complex (Gallus gallus)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Gallus gallus)


name: SDS dimers:PXLP dehydrate L-Thr to 2AA (Saccharomyces cerevisiae)


name: NAD-dependent protein depalmitoylase activity


name: H2O + N(6)-hexadecanoyl-L-lysyl-[protein] + NAD(+) = 2''-O-hexadecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: p-T38-PPP1R14A binds MLCP (Homo sapiens)


name: (2E,6E)-farnesal + H2O + NAD(+) = (2E,6E)-farnesoate + 2 H(+) + NADH


name: GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Sus scrofa)


name: Defective OPN1LW does not bind 11cRAL (Homo sapiens)


name: ADP + H(+) + N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] => ATP + N(6)-D-ribulosyl-L-lysyl-[protein]


name: Activation of TASK (Caenorhabditis elegans)


name: Collagen types VI, IX bind integrin alpha10beta1 (Sus scrofa)


name: 3-O-[alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc]-L-Thr-[protein] + CMP-N-acetyl-beta-neuraminate => 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-Thr-[protein] + CMP + H(+)


name: GRIK3 homomer binds glutamate (Sus scrofa)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)


name: COP9 and TOR1 deneddylate STON2 (Homo sapiens)


name: Na+/H+ exchanger transport (at trans-golgi membrane) (Gallus gallus)


name: NAD(+) + propan-2-ol => acetone + H(+) + NADH


name: AH2 + prostaglandin G1 = A + H2O + prostaglandin H1


name: HHAT palmitoylates Hh N-terminal fragment (Drosophila melanogaster)


name: ABCC3 transports bile salts from cytosol to extracellular region (Canis familiaris)


name: a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)


name: [DNA-directed RNA polymerase] + ATP <=> ADP + H(+) + phospho-[DNA-directed RNA polymerase]


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Canis familiaris)


name: ent-isokaurene-2beta,3beta-diol + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => ent-isokaurene + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Drosophila melanogaster)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Plasmodium falciparum)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA <=> 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + CoA


name: ARSA removes sulfate from SM3 (Mus musculus)


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine = 1,3,3'-tri-O-methyl-4alpha-mannobiose + H(+) + S-adenosyl-L-homocysteine


name: PPA2A dephosphorylates SPRY2 (Xenopus tropicalis)


name: NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Rattus norvegicus)


name: Phosphorylation of beta and gamma subunits by LYN (Bos taurus)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Xenopus tropicalis)


name: 1-O-octadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: L-serine(in) + Na(+)(in) => L-serine(out) + Na(+)(out)


name: Cyclin A:Cdk2 mediated phosphorylation of p27/p21 (Caenorhabditis elegans)


name: 2 3-octadecanoyl-sn-glycero-1-phospho-(1'-sn-glycerol) <=> 3-octadecanoyl-sn-glycero-1-phospho-(3'-octadecanoyl-1'-sn-glycerol) + sn-glycero-1-phospho-(1'-sn-glycerol)


name: 3'-phosphoadenylyl sulfate + H2O => adenosine 5'-phosphosulfate + phosphate


name: 1-hydroxy-6-methoxyphenazine N(10)-oxide + S-adenosyl-L-methionine => 1,6-dimethoxyphenazine N(5)-oxide + S-adenosyl-L-homocysteine


name: STRA6 transports atROL from extracellular region to cytosol (Canis familiaris)


name: ATP + H2O + N-acetyl-L-aspartate(in) => ADP + H(+) + N-acetyl-L-aspartate(out) + phosphate


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Caenorhabditis elegans)


name: PAK1 or PAK2 phosphorylates MYLK (Rattus norvegicus)


name: (20S)-hydroxypregn-4-en-3-one + NADP(+) => H(+) + NADPH + progesterone


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine => (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: H2O + propanoyl-CoA = CoA + H(+) + propanoate


name: ATP + citrate + CoA => acetyl-CoA + ADP + oxaloacetate + phosphate


name: dTDP-6-deoxy-beta-L-talose + NAD(+) <=> dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADH


name: RAR:RXR binds SUMO-CRABP2:atRA (Rattus norvegicus)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Mus musculus)


name: malate + NAD+ <=> oxaloacetate + NADH + H+ (Gallus gallus)


name: 3'-phosphoadenylyl sulfate + a ganglioside GM1b => adenosine 3',5'-bisphosphate + an 8-O-sulfo-ganglioside GM1b + H(+)


name: D-serine(in) + L-glutamine(out) + Na(+)(out) => D-serine(out) + L-glutamine(in) + Na(+)(in)


name: TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 (Homo sapiens)


name: 4-O-deacetylvindoline + acetyl-CoA <=> CoA + vindoline


name: Association of RAD51 with RAD52:DNA double-strand break ends (Xenopus tropicalis)


name: SUCLG1/G2 cleaves succinyl-CoA (Sus scrofa)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Plasmodium falciparum)


name: Glc6P is isomerised to I3P by ISYNA1 in the cytosol (Dictyostelium discoideum)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-alpha-D-galactose = a globoside Gb3Cer + H(+) + UDP


name: 15-demethylaclacinomycin T + AH2 + O2 <=> 10-decarboxymethylaclacinomycin T + A + CO2 + H2O


name: ORC2 binds ORC3 (Schizosaccharomyces pombe)


name: H2O + N-decanoyl-1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine <=> 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + H(+) + N-decanoyl ethanolamine


name: scopoletin + UDP-alpha-D-glucose => H(+) + scopolin + UDP


name: Phospholipase C-gamma1 binds to the activated EGF receptor (Gallus gallus)


name: Formation of the Spliceosomal A complex (Homo sapiens)


name: STAT4 binds IL12RB2:IL12RB2 (Canis familiaris)


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Sus scrofa)


name: 2-phenylacetate + NH4(+) => 2-phenylacetamide + H2O


name: Formation of the outer ring of the 20S core particle (Drosophila melanogaster)


name: Association of Nek2A with MCC:APC/C (Mus musculus)


name: 3-hydroxyphenylacetate + H(+) + NADPH + O2 = H2O + homogentisate + NADP(+)


name: (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ATP + L-glutamate <=> (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + H(+) + phosphate


name: 1-O-hexadecyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H(+) + NADPH <=> 1-O-hexadecyl-2-(5-hydroxypentanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: D-histidine(in) + H(+)(in) + L-ornithine(out) => D-histidine(out) + H(+)(out) + L-ornithine(in)


name: 1-[8-hydroxy-(9Z)-octadecenoyl]-sn-glycero-3-phosphocholine + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + O2 + reduced [NADPH--hemoprotein reductase]


name: 2,4,6-trinitrotoluene + 2 H(+) + 2 NADH => 2-hydroxylamino-4,6-dinitrotoluene + H2O + 2 NAD(+)


name: (3S)-hydroxyhexanoyl-CoA + NAD(+) => 3-oxohexanoyl-CoA + H(+) + NADH


name: The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Mus musculus)


name: H2O + N(6)-[(S)-lactoyl]-L-lysyl-[protein] + NAD(+) = 2''-O-(S)-lactoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide


name: Binding of TFIIIB to TFIIC: Type 2 Promoter Complex (Mus musculus)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)


name: Inactive G alpha (q) reassociates with G beta:gamma (Mus musculus)


name: a primary nitroalkane + H2O + O2 = an aldehyde + H(+) + H2O2 + nitrite


name: alpha-secretase cleaves the p75NTR extracellular domain (Bos taurus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Xenopus tropicalis)


name: 2-dehydro-3-deoxy-6-phospho-D-gluconate => D-glyceraldehyde 3-phosphate + pyruvate


name: NCEH1 hydrolyzes cholesterol esters (Danio rerio)


name: 2-oxoglutarate + dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + L-glutamate


name: (R)-2-hydroxypropyl-coenzyme M => (R)-1,2-epoxypropane + coenzyme M


name: O2 + peregrinol + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase]


name: H(+)(out) + sarcosine(out) => H(+)(in) + sarcosine(in)


name: diphosphate + N(pros)-(5'-guanosyl-phosphono)-L-histidyl-[RNA ligase] => GTP + L-histidyl-[RNA ligase]


name: fibrin multimer, crosslinked -> fibrin digestion products (plasmin) (Caenorhabditis elegans)


name: 4-amino-L-phenylalanine + S-adenosyl-L-methionine = 4-methylamino-L-phenylalanine + H(+) + S-adenosyl-L-homocysteine


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Rattus norvegicus)


name: GLYAT-like proteins transfer glycine to ST-CoA to form SUA (Canis familiaris)


name: 4-nitro-6-oxohepta-2,4-dienedioate => 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Gallus gallus)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Caenorhabditis elegans)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base => a 1,2-diacyl-sn-glycerol + an alpha-D-mannosyl-6-(1D-myo-inositol phospho)-(1<->6)-1D-myo-inositol-1-phospho-N-(2-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base


name: 2-dehydro-3-deoxy-L-galactonate = L-glyceraldehyde + pyruvate


name: MAP2K6 phosphorylates PIP4K2B (Drosophila melanogaster)


name: TRIT1 transfers dimethylallyl group to adenosine-37 of tRNA(Ser) (Homo sapiens)


name: Binding of TFIIIA To type 1 Promoter (Rattus norvegicus)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Sus scrofa)


name: thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Bos taurus)


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Schizosaccharomyces pombe)


name: IL19 binds IL20RA:JAK1:IL20RB (Rattus norvegicus)


name: FDPS dimer transfers IPPP to DMAPP (Sus scrofa)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP <=> 7,8-dihydrofolate + dTMP


name: dihydrorhizobitoxine + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + rhizobitoxine


name: an anthocyanidin + UDP-alpha-D-galactose <=> an anthocyanidin 3-O-beta-D-galactoside + UDP


name: Recruitment of TRAF6/TRAF2 to IPS-1 (Homo sapiens)


name: a long-chain fatty acyl-AMP + holo-[mycocerosate synthase] <=> AMP + H(+) + long-chain fatty acyl-[mycocerosate synthase]


name: inosine + phosphate <=> alpha-D-ribose 1-phosphate + hypoxanthine


name: (5S,18)-dihydroxy-(6E,8Z)-octadecadienoate + H(+) + H2O + oxidized [NADH--hemoprotein reductase] => (5S)-hydroxy-(6E,8Z)-octadecadienoate + O2 + reduced [NADH--hemoprotein reductase]


name: ARSC hydrolyzes steroid sulfates (Xenopus tropicalis)


name: EXT1:EXT2 transfers GlcNAc to heparan (Danio rerio)


name: Interleukin-1 family are secreted (Homo sapiens)


name: 5'-phosphoribosyl-5-aminoimidazole (AIR) + CO2 <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) (Gallus gallus)


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Gallus gallus)


name: 5-N(alpha)-glycyl-dTMP in DNA + phosphate => 5-phosphomethyl-dUMP in DNA + glycine


name: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor


name: 3-methyl-2-butenal + 4'-apo-beta-carotenal => O2 + torulene


name: PLG(20-810) binds anti-fibrinolytics (Rattus norvegicus)


name: MAPKAPK5 phosphorylates TP53 (Homo sapiens)


name: Formation of AT-AC B Complex (Caenorhabditis elegans)


name: L-leucine(in) + L-phenylalanine(out) <=> L-leucine(out) + L-phenylalanine(in)


name: p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Mus musculus)


name: beta-D-glucose + D-glucose => H2O + kojibiose


name: (11Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] => 3-oxo-(13Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]


name: ATP + O-phospho-L-serine + tRNA(Cys) => AMP + diphosphate + O-phospho-L-seryl-tRNA(Cys)


name: (11R)-dihydroartemisinic aldehyde + NADP(+) <=> (+)-artemisinic aldehyde + H(+) + NADPH


name: Trimerization of cytosolic HSF1 (Saccharomyces cerevisiae)


name: loading of Serotonin in synaptic vesicles (Gallus gallus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) + N-dodecanoylethanolamine => H2O + N-dodecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: ATP + glycyl-L-methionine(out) + H2O => ADP + glycyl-L-methionine(in) + H(+) + phosphate


name: aculene D + L-prolyl-[peptidyl-carrier protein] = aculene B + holo-[peptidyl-carrier protein]


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Bos taurus)


name: SESN1,2,3 bind overoxidized PRDX1 (Drosophila melanogaster)


name: PLOD3:Fe2+ dimer:Glucosyl-galactosyl-hydroxylysyl collagen propeptides dissociates (Caenorhabditis elegans)


name: MRN:CtIP exonucleolytically hydrolyzes DNA 3' to SPO11 and SPO11:double-strand break dissociates to SPO11:oligonucleotide and resected 5' end (Homo sapiens)


name: GGT dimers hydrolyse APAP-SG (Caenorhabditis elegans)


name: Protesomal degradation of K48polyUb-TRAF3 (Sus scrofa)


name: DSB inducing agents induce double strand DNA breaks (Homo sapiens)


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Bos taurus)


name: PIP3 binds to RhoA and activates it (Saccharomyces cerevisiae)


name: ABCC4 accumulation of dense granule contents (Gallus gallus)


name: Phosphorylated heterodimers of ERBB2 KD mutants recruit GRB2:SOS1 through SHC1 (Homo sapiens)


name: CBY1 binds beta-catenin (Rattus norvegicus)


name: H(+)(in) + sarcosine(in) => H(+)(out) + sarcosine(out)


name: D-loop formation mediated by PALB2, BRCA2 and RAD51 (Gallus gallus)


name: ATP + H2O + spermidine(out) => ADP + H(+) + phosphate + spermidine(in)


name: Nephrin interacts with Podocin (Canis familiaris)


name: Diiodinated tyrosine can be deiodinated (Rattus norvegicus)


name: androst-4-ene-3,17-dione + O2 + reduced [NADPH--hemoprotein reductase] = 6beta-hydroxyandrost-4-ene-3,17-dione + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PDE3A hydrolyses cAMP to AMP (Homo sapiens)


name: RNA polymerase II C-terminal domain phosphoserine binding


name: TBC1D25 (OATL1) binds ATG8 homologues (Schizosaccharomyces pombe)


name: AUF1:mRNA complex is destroyed (Danio rerio)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Canis familiaris)


name: D-glucose + mandelonitrile => (R)-prunasin + H2O


name: THOP1 cleaves oligopeptide fragment (8-16aa) (Rattus norvegicus)


name: SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Xenopus tropicalis)


name: alpha-NAD(+) + H2O = ADP-D-ribose + H(+) + nicotinamide


name: Rifampicin binds Mtb RNAP (Homo sapiens)


name: MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Caenorhabditis elegans)


name: H2O2 oxidises ferrohemoglobin to MetHb (Canis familiaris)


name: LDL translocates from endosome lumen to lysosome lumen (Rattus norvegicus)


name: guaiacol + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-homocysteine + veratrole


name: holothin + marinoloyl-CoA C <=> CoA + thiomarinol C


name: aclacinomycin T + dTDP-2-deoxy-beta-L-fucose = aclacinomycin S + dTDP + H(+)


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Drosophila melanogaster)


name: Arachidonate is hydroxylated to 18-HETE by CYP(1) (Canis familiaris)


name: dihydro-6-demethylsterigmatocystin + S-adenosyl-L-methionine <=> dihydrosterigmatocystin + H(+) + S-adenosyl-L-homocysteine


name: 2-aryl-2-methylmalonate + H(+) <=> 2-arylpropionate + CO2


name: TNIPs bind TNFAIP3 (A20) (Rattus norvegicus)


name: MASTL (GWL) phosphorylates ARPP19 (Sus scrofa)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + dodecanoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-dodecanoyl-sn-glycerol + CoA


name: Formation of a heteromeric BMP receptor complex (Gallus gallus)


name: MITF-M dimer, SOX10, pS133 CREB1 and CTNNB1:LEF1 bind the DCT promoter (Homo sapiens)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the Golgi membrane (Homo sapiens)


name: sucrose + H2O => glucose + fructose (Bos taurus)


name: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O => 3-maleylpyruvate + H(+)


name: JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)


name: 2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] <=> 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate


name: UGCG transfers glucose to ceramide (Canis familiaris)


name: an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol <=> 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol


name: p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 (Rattus norvegicus)


name: dTDP-6-deoxy-alpha-D-allose + NAD(+) => dTDP-4-dehydro-6-deoxy-alpha-D-allose + H(+) + NADH


name: ATP + hexadecanoate + holo-[ACP] <=> AMP + diphosphate + hexadecanoyl-[ACP]


name: Secretion of SOD3 (Dictyostelium discoideum)


name: carboxynorspermidine + H2O + NADP(+) <=> H(+) + L-aspartate 4-semialdehyde + NADPH + propane-1,3-diamine


name: N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine = H(+) + N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine


name: 1D-myo-inositol hexakisphosphate + H2O <=> 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate


name: H2O + N-acetyl-beta-D-6-sulfogalactosaminyl-(1->4)-alpha-L-iduronyl-(1->3)-N-acetyl-D-6-sulfogalactosamine <=> alpha-L-iduronyl-(1->3)-N-acetyl-D-6-sulfogalactosamine + N-acetyl-D-6-sulfogalactosamine


name: a uridine in mRNA + H(+) + NADPH => a 5,6-dihydrouridine in mRNA + NADP(+)


name: (Z)-2-(indol-3-yl)-1-thioacetohydroximate + UDP-alpha-D-glucose => (Z)-indolylmethyl desulfoglucosinolate + UDP


name: corticosterone + NADP(+) => 11-dehydrocorticosterone + H(+) + NADPH


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Sus scrofa)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Dictyostelium discoideum)


name: Transport of Extracellular Glucose to the Cytosol by GLUT1 and GLUT2 (Xenopus tropicalis)


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Canis familiaris)


name: ADP + dUMP + H(+) => 2'-deoxyuridine + ATP


name: IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Rattus norvegicus)


name: (3R)-3-isopropenyl-6-oxoheptanoate + H2O + NADP(+) => (1S,4R)-1-hydroxylimonen-2-one + NADPH + O2


name: CoA + H(+) + N-octadecanoyl-heptadecasphing-4-enine => heptadecasphing-4-enine + octadecanoyl-CoA


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Gallus gallus)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Mus musculus)


name: isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate (Homo sapiens)


name: brevianamide F + dimethylallyl diphosphate = deoxybrevianamide E + diphosphate


name: "brevianamide F prenyltransferase (deoxybrevianamide E-forming)"


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Plasmodium falciparum)


name: 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde => acetoin + aldehydo-D-ribose 5-phosphate


name: 7-isopropyl-4-methyloxepan-2-one + H2O <=> 6-hydroxy-3,7-dimethyloctanoate + H(+)


name: PPO oxidises PPGEN9 to PRIN9 (Saccharomyces cerevisiae)


name: RUNX1:CBFB, SIN3A(SIN3B), PRMT6 and HDAC1 bind the ITGA2B promoter (Homo sapiens)


name: MEOS oxidizes ethanol to acetaldehyde (Sus scrofa)


name: Cholecystokinin receptors bind cholecystokinin (Mus musculus)


name: ABCA4 mediates atRAL transport (Plasmodium falciparum)


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Danio rerio)


name: PRKACA phosphorylates TNNI3 (Sus scrofa)


name: (5-hydroxyindol-3-yl)acetaldehyde + H2O + NAD(+) <=> (5-hydroxyindol-3-yl)acetate + 2 H(+) + NADH


name: L-tyrosine + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-4-hydroxyphenylacetaldehyde oxime + CO2 + 2 H(+) + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]


name: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid A <=> 4-amino-4-deoxy-beta-L-arabinopyranosyl-lipid A + di-trans,octa-cis-undecaprenyl phosphate


name: glycolate + NAD(+) <=> glyoxylate + H(+) + NADH


name: 3-methylxanthine + formaldehyde + H2O + NAD(+) => H(+) + NADH + O2 + theophylline


name: H2O + N-(9Z-octadecenoyl)-L-glutamate = (9Z)-octadecenoate + L-glutamate


name: PI is exchanged with PC by PITPNB (Xenopus tropicalis)


name: 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine => diphosphate + IMP


name: ANGPTL4 binds to CDH11v (Canis familiaris)


name: 2'-deoxyadenosine + H(+) + triphosphate => dATP + H2O


name: G-protein activated inward rectifier potassium channel activity


name: Activation of GIRK/Kir3 Channels (Homo sapiens)


name: D-arginine + H2O + O2 => 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: HSP90 binds TBK1 and IRF3 (Rattus norvegicus)


name: adenosylcob(III)inamide-GDP + alpha-ribazole <=> adenosylcob(III)alamin + GMP + H(+)


name: 4-hydroxyprotoasukamycin + H2O + NAD(+) => H(+) + NADH + O2 + protoasukamycin


name: (3R)-hydroxy-(11Z)-eicosenoyl-CoA <=> (2E,11Z)-eicosadienoyl-CoA + H2O


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Mus musculus)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-D-GlcNAc + GDP-beta-L-fucose => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc + GDP + H(+)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Sus scrofa)


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Bos taurus)


name: Addition of nucleotides between position +11 and +30 (Mus musculus)


name: DHI and DHICA polymerize forming eumelanin (Bos taurus)


name: Connexin synthesis (generic) (Rattus norvegicus)


name: Phosphorylation of INFAR1 by TYK2 (Homo sapiens)


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Canis familiaris)


name: AP4 transports APP from trans-Golgi network to endosome lumen (Mus musculus)


name: EPHB phosphorylates TIAM1 (Caenorhabditis elegans)


name: pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity


name: ADP + D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H(+) => ATP + D-glycero-beta-D-manno-heptose 7-phosphate


name: Formation of Cyclin E:Cdk2 complexes (Caenorhabditis elegans)


name: CDP-glycerol + diphosphate => CTP + H(+) + sn-glycerol 3-phosphate


name: ISGylation of host proteins (Bos taurus)


name: ATP + N-acetyl-D-muramate = ADP + H(+) + N-acetyl-D-muramate 6-phosphate


name: Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)


name: Enhanced autophagosome formation (Homo sapiens)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine <=> N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA


name: S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) => S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out)


name: Thiosulfate can transfer its sulfur atom to glutathione (Mus musculus)


name: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 (Bos taurus)


name: MYSM1 deubiquitinates Histone H2A (Sus scrofa)


name: (PP)2-IP4 is dephosphorylated to 1/3-PP-IP5 by NUDT(1) in the cytosol (Dictyostelium discoideum)


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Saccharomyces cerevisiae)


name: Formation of fatty acid synthase (FAS) dimer (Canis familiaris)


name: L-tyrosyl-[protein] + NAD(+) = H(+) + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein]


name: NPC transports GCK1:GKRP from cytosol to nucleoplasm (Mus musculus)


name: TGFBR2 recruits TGFBR1 (Canis familiaris)


name: CPT2 converts palmitoyl carnitine to palmitoyl-CoA (Rattus norvegicus)


name: Cleavage of Procaspase-7 by the apoptosome (Rattus norvegicus)


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Mus musculus)


name: prunetin + UDP-alpha-D-glucuronate <=> prunetin-5-O-beta-D-glucuronide + UDP


name: (9Z,12Z,15Z)-octadecatrienoate + O2 => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: apo-UQCRFS1 binds LYRM7 (Xenopus tropicalis)


name: 2 A + glycine = 2 AH2 + CO2 + hydrogen cyanide


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Homo sapiens)


name: AJUBA facilitates AURKA autophosphorylation (Homo sapiens)


name: 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + H(+) + UDP => 2',3,4,4',6'-pentahydroxychalcone + UDP-alpha-D-glucose


name: PGM2:Mg2+ isomerises R1P to R5P (Canis familiaris)


name: POU5F1 and SOX2 bind the ZIC1 gene (Homo sapiens)


name: 2xPPCS ligates PPanK with Cys (Homo sapiens)


name: (2E)-hexenoyl-CoA + H(+) + NADPH <=> hexanoyl-CoA + NADP(+)


name: (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => CoA + H2O


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Dictyostelium discoideum)


name: Synthesis of dolichyl-phosphate-glucose (Homo sapiens)


name: (9E)-octadecenoyl-CoA + FAD + H(+) = (2E,9E)-octadecadienoyl-CoA + FADH2


name: CDC6 association with ORC(1-6) at replication origins (Mus musculus)


name: 18(R)-RvE1, E2 and E3 translocate from cytosol to extracellular region (Homo sapiens)


name: an anthocyanidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose => an anthocyanidin 3,5-di-O-beta-D-glucoside + 2 H(+) + UDP


name: PAKs autophosphorylate (Canis familiaris)


name: ATP + glutathione(in) + H2O = ADP + glutathione(out) + H(+) + phosphate


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Mus musculus)


name: GPR37L binds prosaposin (Canis familiaris)


name: OAT2 and OAT4 mediate transport of sulphate conjugates (Bos taurus)


name: benzoate + H(+) + NADH + O2 => (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: Activated FGFR2:pFRS binds GRB2:SOS1 (Homo sapiens)


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CTP + H(+)


name: ST3GAL5 transfers NeuNAc to ceramides (Bos taurus)


name: 2 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+) + N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: ER calcium channels open in response to activated PKA (Canis familiaris)


name: GOPC promotes translocation of CFTR to lysosomes (Caenorhabditis elegans)


name: N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Danio rerio)


name: luteolin + S-adenosyl-L-methionine => H(+) + luteolin 7-methyl ether + S-adenosyl-L-homocysteine


name: ethylamine + H2O + NAD(+) = acetaldehyde + H(+) + NADH + NH4(+)


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)


name: beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-R + H(+) + UDP => an N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Rattus norvegicus)


name: CYP2F1 dehydrogenates 3-methylindole (Drosophila melanogaster)


name: D-glycero-D-manno-heptose 1,7-bisphosphate + H2O => D-glycero-D-manno-heptose 1-phosphate + phosphate


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene + A => 1,1'-dihydroxy-3,4-didehydro-1,2-dihydrolycopene + AH2


name: Hh-Np binds SCUBE2 in the extracellular region to promote long-range signalling (Homo sapiens)


name: Duplex siRNA is loaded into Argonaute (Caenorhabditis elegans)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Myristoylation of tBID by NMT1 (Gallus gallus)


name: 7-oxocholesterol + H(+) + NADPH <=> 7alpha-hydroxycholesterol + NADP(+)


name: Cleavage of uracil by MBD4 glycosylase (Xenopus tropicalis)


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Canis familiaris)


name: Caspase mediated cleavage of HIP-55 (Drosophila melanogaster)


name: K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Sus scrofa)


name: De-phosphorylation of p-Y427-SHC1 (Homo sapiens)


name: RP2:ARL3:GDP:UNC119B dissociates (Mus musculus)


name: (beta-L-Ara4N)2-(Kdo)2-lipid A(in) + ATP + H2O => (beta-L-Ara4N)2-(Kdo)2-lipid A(out) + ADP + H(+) + phosphate


name: Cleavage of 3-methyladenine by MPG glycosylase  (Danio rerio)


name: HS6STs sulfate GlcN at C6 in heparan sulfate/heparin (Caenorhabditis elegans)


name: a nucleoside 2',3'-cyclic phosphate + H2O = a nucleoside 2'-phosphate + H(+)


name: (4R)-hydroxysphinganine + tetracosanoyl-CoA => CoA + H(+) + N-tetracosanoyl-(4R)-hydroxysphinganine


name: NTF4-bound NTRK2 dimerizes (Homo sapiens)


name: N-terminal L-cysteinyl-[protein] + O2 = H(+) + N-terminal S-hydroxy-S-oxy-L-cysteinyl-[protein]


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Bos taurus)


name: (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + NADP(+) => (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H(+) + NADPH


name: (R)-mandelate + NAD(+) <=> H(+) + NADH + phenylglyoxylate


name: EDNRA binds selective ERAs (Danio rerio)


name: Release of p-STAT2:p-STAT1 dimer (Xenopus tropicalis)


name: thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators (Mus musculus)


name: MECP2 is phosphorylated at S423 (Homo sapiens)


name: SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) (Bos taurus)


name: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA <=> CoA + N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2]


name: Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Caenorhabditis elegans)


name: 2-methoxybenzaldehyde + hydrogen cyanide => (2S)-2-hydroxy-2-(2-methoxyphenyl)acetonitrile


name: AMP + diphosphate + L-cysteinyl-[peptidyl-carrier protein] => ATP + holo-[peptidyl-carrier protein] + L-cysteine


name: 2,4-dinitrophenyl-S-glutathione(in) + ATP + H2O => 2,4-dinitrophenyl-S-glutathione(out) + ADP + H(+) + phosphate


name: 2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 => 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate


name: CRK,CRKL recruits RAC1 GEF to activated MET (Gallus gallus)


name: acetyl-CoA + an N-terminal L-alpha-aminoacyl-[protein] <=> CoA + H(+) + N-terminal N(alpha)-acetyl-L-alpha-aminoacyl-[protein]


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Bos taurus)


name: Initial activation of proMMP13 by MMP14 (MT1-MMP) (Canis familiaris)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Bos taurus)


name: ATP + pseudouridine <=> ADP + H(+) + psi-UMP


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O <=> (9Z)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H(+)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = CMP + H(+) + N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide


name: Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region (Homo sapiens)


name: dUTP + H2O => dUMP + pyrophosphate (Homo sapiens)


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Sus scrofa)


name: 2 H(+) + methylmalonate + NADH => (S)-2-methyl-3-oxopropanoate + H2O + NAD(+)


name: Syndecans 1, 2, 4, (3) bind FGF2 (Caenorhabditis elegans)


name: HRSP12 deaminates 2AA to 2OBUTA (Drosophila melanogaster)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 + reduced [NADPH--hemoprotein reductase] = (19S,20R)-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: (-)-casbene + O2 + reduced [NADPH--hemoprotein reductase] <=> 4-hydroxycasbene + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: Histone acetyltransferases are recruited to the TFF1 gene (Gallus gallus)


name: (9Z)-octadecenoate + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O


name: aldehyde ferredoxin oxidoreductase activity


name: N-hydroxy-L-trihomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-trihomomethionine + oxidized [NADPH--hemoprotein reductase]


name: 2-formylbenzoate + H2O + NAD(+) => 2 H(+) + NADH + phthalate


name: HSD17B1 hydrogenates E1 to EST17b (Mus musculus)


name: 2 H(+) + hexadecanoyl-[ACP] + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (6Z)-hexadecenoyl-[ACP] + 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine = 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: CDK5:p25 phosphorylates PRDX2 (Homo sapiens)


name: p-S158,221-HuR binds mRNA (Drosophila melanogaster)


name: cellobiose transmembrane transporter activity


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Rattus norvegicus)


name: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine => 3,3',4',5,7-pentahydroxy-8-methoxyflavone + H(+) + S-adenosyl-L-homocysteine


name: RHOJ binds effectors at the plasma membrane (Homo sapiens)


name: p-PKR dimer phosphorylates ILF3:ILF2 (Sus scrofa)


name: FeHM dissociates from MetHb (Bos taurus)


name: PAK1 or PAK2 phosphorylates MYLK (Gallus gallus)


name: Gi activation by P2Y purinoceptor 12 (Mus musculus)


name: Collagen type VII dimerization (Mus musculus)


name: "(Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase"


name: doxorubicin(in) + H(+)(out) <=> doxorubicin(out) + H(+)(in)


name: Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation (Sus scrofa)


name: NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Drosophila melanogaster)


name: acetoin + NADP(+) => diacetyl + H(+) + NADPH


name: O2 + reduced [NADPH--hemoprotein reductase] + testosterone => 11beta,17beta-dihydroxyandrost-4-ene-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: SEC4C,D bind GOSR2 and STX5 (Saccharomyces cerevisiae)


name: RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Homo sapiens)


name: PTPN3 dephosphorylates EPS15 (Homo sapiens)


name: Activated FYN binds GRIN2B (Homo sapiens)


name: (2Z,6E)-farnesyl diphosphate = beta-bisabolene + diphosphate


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)


name: IL12B:IL12B translocates from ER lumen to the extracellular region (Danio rerio)


name: benzyl acetate + H2O + NADP(+) => H(+) + NADPH + O2 + phenylacetone


name: 2 H2O + L-dehydroascorbate => H2O2 + L-ascorbate


name: Defective CYP21A2 does not 21-hydroxylate PROG (Homo sapiens)


name: a ribonucleotide in rRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in rRNA + H(+) + S-adenosyl-L-homocysteine


name: RANBP2 SUMOylates MDM2 with SUMO1 (Bos taurus)


name: Formation of RAD52 heptameric ring structure complexes (Gallus gallus)


name: FOXO1,FOXO3 and SMAD3 bind TRIM63 gene promoter (Homo sapiens)


name: 2 H(+) + O2 + pentalen-13-ol + 2 reduced [2Fe-2S]-[ferredoxin] => 2 H2O + 2 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al


name: (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Sus scrofa)


name: Active Rac1 interacts with Plexin-B1:Sema4D (Gallus gallus)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated (Homo sapiens)


name: N-WASP binds ARP2/3 and G-actin (Caenorhabditis elegans)


name: 3-dimethylallyl-4-hydroxyphenylpyruvate + diphosphate => 3-(4-hydroxyphenyl)pyruvate + dimethylallyl diphosphate


name: 3-iodo-L-tyrosine + NADPH => iodide + L-tyrosine + NADP(+)


name: 4alpha-formyl-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + H(+) + O2 => 4alpha-carboxy-stigmasta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Sus scrofa)


name: L-phenylalanine + taurocholate => L-phenylalanocholate + taurine


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Sus scrofa)


name: HEXB cleaves the terminal GalNAc from DS (Homo sapiens)


name: brassinolide + H(+) + H2O + oxidized [NADPH--hemoprotein reductase] => castasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Xenopus tropicalis)


name: didemethylasterriquinone D + dimethylallyl diphosphate <=> asterriquinone C1 + diphosphate


name: 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O-[alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + H(+) + UDP


name: NADPH transfers electrons to FDXR (Dictyostelium discoideum)


name: SH2B proteins bind JAK2 (Drosophila melanogaster)


name: PLK1 phosphorylates GTSE1 (Homo sapiens)


name: H(+) + N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine => L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + cholesterol = (5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterol + CoA


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + H(+) + malonyl-CoA => (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA


name: (2E,6E)-hedycaryol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Caenorhabditis elegans)


name: eicosanoyl-CoA + taurine => CoA + H(+) + N-eicosanoyl-taurine


name: (2E,6E,10E,14E)-geranylfarnesol + H2O = (17E)-cheilanthenediol


name: ganglioside GT1b (d18:1(4E)/18:0) + H2O => ganglioside GD1b(d18:1(4E)/18:0) + N-acetylneuraminate


name: CR:atREs binds apoE and HSPG (Mus musculus)


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Danio rerio)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Rattus norvegicus)


name: p-Y-STAT1,3,5 dimer binds SOCS3 gene (Homo sapiens)


name: FPGS-2 transforms THF to THFPG (Danio rerio)


name: Ubiquitination of phospho-p27/p21 (Gallus gallus)


name: cGMP is degraded by PDEs (Plasmodium falciparum)


name: NBR1 binds ATM:Ub-p-PEX5:SQSTM1 (Gallus gallus)


name: Activated PLC gamma dissociates from the PDGF receptor (Sus scrofa)


name: (S)-scoulerine + S-adenosyl-L-methionine => (S)-tetrahydrocolumbamine + H(+) + S-adenosyl-L-homocysteine


name: Thiolysis of 3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA yields chenodeoxycholoyl-CoA (3alpha,7alpha-dihydroxy-5beta-cholan-24-one-CoA) and propionyl CoA (Bos taurus)


name: glutamate uptake by astrocytes (Bos taurus)


name: 2 a menaquinol + n H(+)(in) + O2 => 2 a menaquinone + n H(+)(out) + 2 H2O(in)


name: H2O + N(2)-(4-aminobutanoyl)-L-arginine <=> 4-aminobutanoate + L-arginine


name: CLCN4/5/6 exchange Cl- for H+ (Sus scrofa)


name: ATP + butanoyl-CoA + hydrogencarbonate <=> (2S)-ethylmalonyl-CoA + ADP + H(+) + phosphate


name: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H(+) + phosphate


name: cytidine(839) in 12S rRNA + S-adenosyl-L-methionine => H(+) + N(4)-methylcytidine(839) in 12S rRNA + S-adenosyl-L-homocysteine


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Xenopus tropicalis)


name: (2S)-N-acetylazetidine-2-carboxylate + CoA + H(+) => (S)-azetidine-2-carboxylate + acetyl-CoA


name: CDP-DAG is converted to PI by CDIPT (Plasmodium falciparum)


name: holo-[(phenol)carboxyphthiodiolenone synthase] + icosanoyl-AMP = AMP + H(+) + icosanoyl-[(phenol)carboxyphthiodiolenone synthase]


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Rattus norvegicus)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Sus scrofa)


name: H(+) + L-dopa + NADH => 3-(3,4-dihydroxyphenyl)propanoate + NAD(+) + NH4(+)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Dictyostelium discoideum)


name: Conversion of Glycerol to Glycerol-3-phosphate (Plasmodium falciparum)


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA => 1-O-hexadecyl-sn-glycero-3-phosphocholine + acetyl-CoA


name: aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate (Homo sapiens)


name: RSF complex binds the centromere (Mus musculus)


name: 3-hydroxyphenylacetate + H(+) + NADH + O2 <=> H2O + homogentisate + NAD(+)


name: Dissociation of phosphorylated MAP2Ks and MAPKs (Drosophila melanogaster)


name: reduced coenzyme F420 dehydrogenase activity


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Bos taurus)


name: methyl salicylate + S-adenosyl-L-homocysteine => S-adenosyl-L-methionine + salicylate


name: Transhomodimerization of Nectins (Homo sapiens)


name: Transport of the export-competent mRNP complex through the NPC (Sus scrofa)


name: TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)


name: transcription elongation factor activity


name: PI3K inhibitors block PI3K catalytic activity (Homo sapiens)


name: Cdc45 associates with the pre-replicative complex at the origin (Sus scrofa)


name: 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol + CO2 + methylamine => carbofuran + H(+) + H2O


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Schizosaccharomyces pombe)


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Homo sapiens)


name: (2Z,6E)-farnesyl diphosphate = (-)-beta-curcumene + diphosphate


name: p-6Y-VEGFR2 binds SH2D2A (Canis familiaris)


name: 2-phenylethanol + 2 Fe(III)-[cytochrome c] => 2-phenylacetaldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is translocated from the cytosol to the mitochondrial matrix (Homo sapiens)


name: Dissociation of the COP1-p53 complex (Xenopus tropicalis)


name: AMPK phosphorylates TP53 (Drosophila melanogaster)


name: malonyl-CoA + rhaponticin => 6-O-malonyl-rhaponticin + CoA


name: CDP-DAG is converted to PI by CDIPT (Schizosaccharomyces pombe)


name: glucoerucin + H2O <=> (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose


name: 2 2',3,4-trihydroxy-trans-chalcone + 2 H(+) + O2 = 2 3',4'-dihydroxyaurone + 2 H2O


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Mus musculus)


name: SLC36A4 transports extracellular L-Pro to the cytosol (Gallus gallus)


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Drosophila melanogaster)


name: H(+) + lithocholoyl-3-O-(beta-D-glucuronate) + UDP => lithocholate + UDP-alpha-D-glucuronate


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + H(+) + O2 + 2 reduced [adrenodoxin] <=> (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + H2O + 2 oxidized [adrenodoxin]


name: GST dimers cleave AZA to 6MP (Canis familiaris)


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Homo sapiens)


name: p52:RELB translocates from cytosol to nucleus (Canis familiaris)


name: ALOX5 oxidises 15S-HpETE to LXA4/B4 (Homo sapiens)


name: NADP(+) + reduced [flavodoxin] <=> 2 H(+) + NADPH + oxidized [flavodoxin]


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Sus scrofa)


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Danio rerio)


name: apulose 4-phosphate + D-glyceraldehyde 3-phosphate = D-xylulose 5-phosphate + dihydroxyacetone phosphate


name: Spike binds Spike inhibitors (Homo sapiens)


name: Ubiquitination of IKBKG by TRAF6 (Mus musculus)


name: [DsbD protein]-disulfide + [protein]-dithiol => [DsbB protein]-dithiol + [protein]-disulfide


name: Arachidonate is hydroxylated to 19-HETE by CYP(2) (Caenorhabditis elegans)


name: ME1 tetramer decarboxylates MAL to PYR (Bos taurus)


name: p-S256-Aquaporin-2 passively transports water into cell (Mus musculus)


name: MIA2 and MIA3 dissociate from procollagen VII vesicle (Rattus norvegicus)


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde => H(+) + H2O + quinolinate


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + H2O = 5-amino-6-(5-phospho-D-ribitylamino)uracil + NH4(+)


name: Factor H binds to membrane-associated C3b (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + phosphate


name: Shootin-1 links L1 and retrograde actin flow (Homo sapiens)


name: RASA1 stimulates RAS GTPase activity (Xenopus tropicalis)


name: 2,2'-iminodipropanoate + H2O + NAD(+) => H(+) + L-alanine + NADH + pyruvate


name: a ubiquinol + D-glucono-1,5-lactone => a ubiquinone + D-glucose


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Bos taurus)


name: N-carbamoylputrescine + NH4(+) => agmatine + H2O


name: 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADH => 2-deoxy-scyllo-inosamine + NAD(+)


name: deamido-NAD(+) + diphosphate => ATP + H(+) + nicotinate beta-D-ribonucleotide


name: Sprouty lures CBL away from EGFR (Bos taurus)


name: an N-acylethanolamine phosphate + H2O <=> an N-acylethanolamine + phosphate


name: Formation of PRC2-EZH2 complex (Bos taurus)


name: Translocation of CARMA1 to Plasma membrane (Xenopus tropicalis)


name: 1-O-(4-hydroxy-3-methoxybenzoyl)-beta-D-glucose + cyanidin 3-O-beta-D-glucoside <=> cyanidin 3,7-di-O-beta-D-glucoside + vanillate


name: SARS-CoV-1 E binds BCL2L1 (Homo sapiens)


name: fumarate + L-cysteinyl-[protein] => S-(2-succinyl)-L-cysteinyl-[protein]


name: Degradation of multiubiquitinated cell cycle proteins (Bos taurus)


name: 4-(gamma-L-glutamylamino)butanoy-[BtrI ACP] + FMNH2 + O2 <=> 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + FMN + H(+) + H2O


name: PPM1D dephosphorylates RUNX2 (Sus scrofa)


name: Nascent G signal peptide is cleaved at ER membrane (Homo sapiens)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Homo sapiens)


name: O-atom dealkylation of dextromethorphan (Canis familiaris)


name: SUMO-CRABP2 dissociates from atRA:RAR:RXR (Rattus norvegicus)


name: Recruitment of SLP-76 to Gads (Bos taurus)


name: AZD1979 + H2O = AZD1979 oxetane hydrolysis product + H(+)


name: SLC22A18 exchanges extracellular organic cations for cytosolic H+ (Gallus gallus)


name: 4-methylene-L-glutamate + NH4(+) => 4-methylene-L-glutamine + H2O


name: FAD attaches to SDHA (Drosophila melanogaster)


name: CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Rattus norvegicus)


name: CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]


name: 2 Fe(II)-[cytochrome b5] + 2 H(+) + N(omega)-hydroxy-N(delta)-methyl-L-arginine <=> 2 Fe(III)-[cytochrome b5] + H2O + N(delta)-methyl-L-arginine


name: 1D-myo-inositol 1-phosphate + phosphate => 1D-myo-inositol 1,3-bisphosphate + H2O


name: apolipoprotein(a) + LDL => Lp(a) (Homo sapiens)


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Bos taurus)


name: Cross-linking of FCGRIA with IgG-coated Ag (Bos taurus)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Canis familiaris)


name: Binding of p85 subunit of PI3K (PIK3R1) to p-ERBB4cyt1 homodimers (Rattus norvegicus)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Danio rerio)


name: docosanoate + O2 + reduced [NADPH--hemoprotein reductase] <=> 22-hydroxydocosanoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH


name: ME1 tetramer decarboxylates OA to PYR (Homo sapiens)


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + NADP(+) => 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + H(+) + NADPH


name: TMEM55B translocates to the nucleus (Rattus norvegicus)


name: 2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Dictyostelium discoideum)


name: 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O => 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Drosophila melanogaster)


name: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H2O


name: 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)


name: Transcription of PPP1R15A (Homo sapiens)


name: Endocytosis of protein 3a (Homo sapiens)


name: PRKACA phosphorylates TNNI3 (Xenopus tropicalis)


name: eicosanoyl-CoA + H(+) + malonyl-CoA => 3-oxodocosanoyl-CoA + CO2 + CoA


name: butanoyl-CoA + serotonin => CoA + H(+) + N-butanoylserotonin


name: 14-3-3 proteins bind AKT-phosphorylated FOXO1 (Xenopus tropicalis)


name: 2-hydroxyglutarate + acetyl-CoA = 2-hydroxyglutaryl-CoA + acetate


name: L-phenylalanine = (E)-cinnamate + NH4(+)


name: (S)-8-oxocitronellyl enol + NADP(+) => (6E)-8-oxogeranial + H(+) + NADPH


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Sus scrofa)


name: (11R)-dihydroartemisinic aldehyde + H2O + NADP(+) => (11R)-dihydroartemisinate + 2 H(+) + NADPH


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Dictyostelium discoideum)


name: MAPK4,6 translocate to nucleus (Plasmodium falciparum)


name: p-T38-PPP1R14A binds MLCP (Drosophila melanogaster)


name: SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Sus scrofa)


name: H2O + S-(hercyn-2-yl)-L-cysteine S-oxide => hercynine + L-cysteine + O2


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + H(+) + S-adenosyl-L-homocysteine


name: 2,4-dimethylbenzyl alcohol + O2 => 2,4-dimethylbenzaldehyde + H2O2


name: Initial proteolyis of Ii by aspartic proteases to lip22 (Rattus norvegicus)


name: an inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP-alpha-D-mannose <=> an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + GDP + H(+)


name: N(6)-methyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-methionine => H(+) + N(6),N(6)-dimethyl-L-lysyl(9)-[histone H3] + S-adenosyl-L-homocysteine


name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Rattus norvegicus)


name: FMN + H2O + NAD(+) => FMN-N(5)-oxide + H(+) + NADH


name: 4,5,8-trihydroxycasbene + 2 NAD(+) => 2 H(+) + jolkinol C + 2 NADH


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Plasmodium falciparum)


name: SFTPB gene produces pro-SFTPB protein (Homo sapiens)


name: (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein] => (9Z)-octadecenoyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: Hemoglobin:Haptoglobin:CD163 is endocytosed (Gallus gallus)


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Danio rerio)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Schizosaccharomyces pombe)


name: p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Gallus gallus)


name: 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 => 1-acyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Localization of CBL:GRB2 to the membrane (Danio rerio)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Canis familiaris)


name: K63polyUb-RIPK1 is deubiquitinated (Homo sapiens)


name: SLITs bind keratan sulfate (Canis familiaris)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Canis familiaris)


name: SLC9A6,7 exchange Na+ for H+ across the early endosome membrane (Saccharomyces cerevisiae)


name: an isothiocyanate + sulfate => a (Z)-N-(sulfonatooxy)alkanimidothioate


name: N(2)-(1-hydroxy-2-oxopropyl)-dGTP => dGTP + methylglyoxal


name: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2 = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+)


name: H2O + N(8)-acetylspermidine = acetate + spermidine


name: glutathione + hydrogenselenide + NADP(+) => glutathioselenol + NADPH


name: Branching and elongation of mother and daughter filaments (Drosophila melanogaster)


name: (1R,3R)-chrysanthemoyl-CoA + (Z,S)-cinerolone = cinerin I + CoA


name: L-methionine transmembrane transporter activity


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Mus musculus)


name: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a CDP-1,2-diacyl-sn-glycerol <=> a cardiolipin + CMP + H(+)


name: GalNAc-T178-FGF23(25-251) translocates from Golgi lumen to extracellular region (Xenopus tropicalis)


name: [Glu(-Cys)](n)-Gly + glutathione + H(+) <=> [Glu(-Cys)](n+1)-Gly + glycine


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Sus scrofa)


name: IL37 binds 2x(CASP1(120-197):CASP1(317-404)) (Canis familiaris)


name: a 2-hydroxyornithine lipid + CO2 + succinate => 2-oxoglutarate + an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + O2


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Sus scrofa)


name: (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+) => FMNH2 + N-methylnicotinate + O2


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Gallus gallus)


name: PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)


name: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) => 2 cob(II)yrinate a,c diamide + FMNH2


name: Substrate translocates into late endosomal lumen (Homo sapiens)


name: Thiosulfate can transfer its sulfur atom to glutathione (Bos taurus)


name: Neurotensin receptors can bind neurotensins (Homo sapiens)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Xenopus tropicalis)


name: MARK3 phosphorylates KSR1 (Dictyostelium discoideum)


name: cyclohexylamine + H2O + NADP(+) = cyclohexanone + H(+) + NADPH + NH4(+)


name: SLC7A2, isoform B (CAT-2B)-mediated uptake of cationic amino acids (Xenopus tropicalis)


name: PKC-delta is activated (Dictyostelium discoideum)


name: Formation of the MLL3 complex (Rattus norvegicus)


name: ATP + H2O + levoglucosan => ADP + D-glucose 6-phosphate + H(+)


name: Activated FGFR3 binds FRS3 (Mus musculus)


name: H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate


name: oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor


name: 2,5-dichlorohydroquinone + 2 glutathione = chloride + chlorohydroquinone + glutathione disulfide + H(+)


name: ITCH polyubiquitinates TP73 (Sus scrofa)


name: PIP3 binds to RhoA and activates it (Sus scrofa)


name: Fe(II)-heme b-[protein] + nitric oxide + O2 <=> Fe(III)-heme b-[protein] + nitrate


name: Transhomodimerization of Nectins (Caenorhabditis elegans)


name: histone H3K27 monomethyltransferase activity


name: KCNK dimers transport K+ from cytosol to extracellular region (Sus scrofa)


name: an n-alkanal + NADP(+) => an alk-2-enal + H(+) + NADPH


name: CTP(in) + IDP(out) => CTP(out) + IDP(in)


name: Expression of ZSCAN4 in the embryo (Homo sapiens)


name: (2S)-dihydrotricetin + 2 H(+) + 2 H2O + 2 oxidized [NADPH--hemoprotein reductase] => (2S)-naringenin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: GH:GHR:JAK2 complex undergoes a conformational change (Homo sapiens)


name: 4-methylquinoline + A + H2O = 4-methylquinolin-2(1H)-one + AH2


name: 1,2-dihexanoylglycerol + hexadecanoyl-CoA => 1,2-dihexanoyl-3-hexadecanoylglycerol + CoA


name: phosphate(in) + sulfate(out) <=> phosphate(out) + sulfate(in)


name: 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine <=> 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine


name: a (2S)-2-hydroxycarboxylate + NADP(+) => a 2-oxocarboxylate + H(+) + NADPH


name: 3beta-hydroxy-5alpha-androstan-17-one + H(+) + NADPH => 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)


name: (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + H(+) + 2 H2O + oxidized [NADPH--hemoprotein reductase] => 6-deoxycathasterone + O2 + reduced [NADPH--hemoprotein reductase]


name: 3'-phosphoadenylyl sulfate + 3,3'-diiodo-L-thyronine <=> 3,3'-diiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane (Caenorhabditis elegans)


name: 2,6-dimethylheptanoyl-CoA + H2O => 2,6-dimethylheptanoate + CoA + H(+)


name: MAPKs phosphorylate PP2A (Rattus norvegicus)


name: ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans (Sus scrofa)


name: superoxide-generating NADH oxidase activity


name: NADH + 2 O2 = H(+) + NAD(+) + 2 superoxide


name: PC:PITPNB is transported from the Golgi membrane to the ER membrane (Plasmodium falciparum)


name: hyodeoxycholate + UDP-alpha-D-glucuronate <=> H(+) + hyodeoxycholate 6-O-(beta-D-glucuronate) + UDP


name: desmosterol + O2 + reduced [NADPH--hemoprotein reductase] => (24Z),26-hydroxydesmosterol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Drosophila melanogaster)


name: ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate => ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln)


name: H(+) + malonyl-CoA + tetracosanoyl-CoA <=> 3-oxohexacosanoyl-CoA + CO2 + CoA


name: 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Canis familiaris)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Canis familiaris)


name: AKR1B15 reduces EST17b to E1 (Danio rerio)


name: alpha-D-glucose + beta-D-fructose => H2O + sucrose


name: C3a receptor binds anaphylatoxin C3a (Bos taurus)


name: (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate D-mannose -> mannose (a1-6) (ethanolamineP) mannose (a1-4) glucosaminyl-acyl-PI + dolichol phosphate (Rattus norvegicus)


name: B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Danio rerio)


name: 7alpha-hydroxycholest-4-en-3-one + O2 + reduced [NADPH--hemoprotein reductase] => 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: PP2A dephosphorylates serine-127 of YAP1 (Caenorhabditis elegans)


name: NADPH oxidase 2 generates superoxide from oxygen (Canis familiaris)


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Bos taurus)


name: CYBRD1:Heme reduces Fe3+ to Fe2+ (Homo sapiens)


name: FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Drosophila melanogaster)


name: 2-dehydro-3-deoxy-L-fuconate => (S)-lactaldehyde + pyruvate


name: METAP1/2 demethylates GNAT1 (Schizosaccharomyces pombe)


name: arginine + H2O => ornithine + urea [ARG1] (Canis familiaris)


name: CBL binds TGFBR2 (Drosophila melanogaster)


name: an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate <=> an alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GalNAc-R + CMP + H(+)


name: N-hydroxy-L-hexahomomethionine + O2 + reduced [NADPH--hemoprotein reductase] = H(+) + H2O + N,N-dihydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase]


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Canis familiaris)


name: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + H(+) => 1D-myo-inositol 1,3,4-trisphosphate + ATP


name: The ABCC family mediates organic anion transport (Xenopus tropicalis)


name: PGRMC2:Hemes dissociates (Schizosaccharomyces pombe)


name: (2E,6E,10E)-geranylgeranyl phosphate + ADP + H(+) => (2E,6E,10E)-geranylgeraniol + ATP


name: PDP1,2 dephosphorylate p-lipo-PDH (Homo sapiens)


name: Phosphorylation of JAK2 (Xenopus tropicalis)


name: NF-kappa-B complex is transported from cytosol to nucleus (Homo sapiens)


name: prostaglandin E1(out) <=> prostaglandin E1(in)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Xenopus tropicalis)


name: SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Rattus norvegicus)


name: (8Z,11Z,14Z)-eicosatrienoyl-CoA + NADP(+) => (2E,8Z,11Z,14Z)-eicosatetraenoyl-CoA + H(+) + NADPH


name: oxaloacetate + phosphate => hydrogencarbonate + phosphoenolpyruvate


name: L-arginine(in) + L-phenylalanine(out) => L-arginine(out) + L-phenylalanine(in)


name: GTP + pyruvate = GDP + H(+) + phosphoenolpyruvate


name: CCND3,(CCND1,CCND2) binds RUNX1 (Danio rerio)


name: POLZ extends translesion synthesis (Schizosaccharomyces pombe)


name: (4S)-limonene + H(+) + NADH + O2 = H2O + limonene 1,2-epoxide + NAD(+)


name: S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine


name: O2 + oxo-taxadiene-4alpha-ol + reduced [NADPH--hemoprotein reductase] => H(+) + H2O + oxidized [NADPH--hemoprotein reductase] + oxo-taxadiene-4alpha,9alpha-diol


name: POLD,POLE-mediated DNA strand displacement synthesis (Dictyostelium discoideum)


name: D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate + H(+) + NADPH


name: The exocyst complex binds to RAB3IP in the ciliary targeting complex (Drosophila melanogaster)


name: Transport of antigen loaded MHC II molecules to surface (Bos taurus)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Bos taurus)


name: 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine => diphthine methyl ester-[translation elongation factor 2] + 3 H(+) + 4 S-adenosyl-L-homocysteine


name: SLIT2 gene expression is stimulated by ISL1 (Homo sapiens)


name: 3-hydroxypropanoyl-CoA = acryloyl-CoA + H2O


name: Addition of nucleotides leads to transcript elongation (Mus musculus)


name: PRKN ubiquitinates MOM substrates (Homo sapiens)


name: DHF is reduced to tetrahydrofolate (THF) (Canis familiaris)


name: SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Danio rerio)


name: UROS transforms HMB to URO3 (Homo sapiens)


name: BESTs transport cytosolic Cl- to extracellular region (Drosophila melanogaster)


name: RAB6:GTP binds the GARP and COG complexes, t-SNAREs and endosome-derived vesicles (Homo sapiens)


name: Formation of HIF:CBP:p300 complex at promoters (Sus scrofa)


name: ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Canis familiaris)


name: (indol-3-yl)acetate + ATP + H(+) = (indol-3-yl)acetyl-AMP + diphosphate


name: 5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Schizosaccharomyces pombe)


name: histone H3K9me2/H3K9me3 demethylase activity


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Homo sapiens)


name: 2 (2S)-bisdechlorogeodin + 2 H2O => 2 H(+) + O2 + 2 sulochrin


name: 2 H(+) + 3 H2O + melianol + 2 oxidized [NADPH--hemoprotein reductase] => dihydroniloticin + 2 O2 + 2 reduced [NADPH--hemoprotein reductase]


name: GS-MCA spontaneously hydrolyzes (Homo sapiens)


name: TGFBR3(784-851) degradation (Bos taurus)


name: Dephosphorylation and dissociation of RNA polymerase II at 3' end of snRNA gene (Homo sapiens)


name: PRKN polyubiquitinates RIPK3 (Canis familiaris)


name: PRKCZ autophosphorylates downstream of estrogen stimulation (Caenorhabditis elegans)


name: A4GALT transfers galactose to LacCer (Canis familiaris)


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Gallus gallus)


name: 5 H(+)(in) + menaquinone-8 + NADH = 4 H(+)(out) + menaquinol-8 + NAD(+)


name: pS181-S-Farn-Me KRAS4B binds BCL2L1 (Homo sapiens)


name: 2'''-acetyl-6'''-hydroxyneomycin C + H(+) + UDP => ribostamycin + UDP-N-acetyl-alpha-D-glucosamine


name: anhydrotetracycline + H(+) + S-adenosyl-L-homocysteine => 4-methylamino-4-dedimethylamino-anhydrotetracycline + S-adenosyl-L-methionine


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-alpha-D-glucose <=> delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP


name: KCNK dimers transport K+ from cytosol to extracellular region (Caenorhabditis elegans)


name: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose


name: SHP2 binds to the active receptor (Rattus norvegicus)


name: (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA + NAD(+) = 3,22-dioxochol-4-en-24-oyl-CoA + H(+) + NADH


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Canis familiaris)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Sus scrofa)


name: H(+) + hexadecanoyl-CoA + NADH => CoA + hexadecanal + NAD(+)


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Homo sapiens)


name: n ATP + H2O + n L-ornithine => n AMP + n diphosphate + n H(+) + N(5)-(L-ornithyl)-[N(5)-(L-ornithyl)]n-1


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Schizosaccharomyces pombe)


name: noranthrone + O2 = H2O + norsolorinic acid


name: 2 iodide + L-tyrosine + 2 NADP(+) = 3,5-diiodo-L-tyrosine + H(+) + 2 NADPH


name: ETA is phosphorylated to PETA by CHK/ETNK (Schizosaccharomyces pombe)


name: FLVCR1-1 transports heme from cytosol to extracellular region (Bos taurus)


name: SLC29A1 transports RBV from cytosol to extracellular region (Canis familiaris)


name: HEYL binds CDH11 gene promoter (Homo sapiens)


name: FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Mus musculus)


name: (3R)-hydroxydocosanoyl-CoA + NAD(+) => 3-oxodocosanoyl-CoA + H(+) + NADH


name: A + H2O + quinolin-5-ol => 5-hydroxyquinolin-2(1H)-one + AH2


name: ALDH2 transforms GTN to NO (Schizosaccharomyces pombe)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)


name: acetyl-CoA + cyathatriol <=> 11-O-acetylcyathatriol + CoA


name: Connexin oligomerization in endoplasmic reticulum membrane (Gallus gallus)


name: D-glyceraldehyde 3-phosphate + L-arginine => H(+) + N(2)-(2-carboxyethyl)-L-arginine + phosphate


name: 3,4-dihydroxyphenylacetate + H(+) <=> 4-methylcatechol + CO2


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Homo sapiens)


name: H(+) + N-[(R)-pantothenoyl]-L-cysteine <=> (R)-pantetheine + CO2


name: Inhibition of integrin activation by sequestering PIP5KIgamma (Canis familiaris)


name: a 1-O-alkyl-2-acetyl-sn-glycerol + an acyl-CoA <=> a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Saccharomyces cerevisiae)


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + H(+) + malonyl-CoA = (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA


name: 3-oxotetradecanedioyl-CoA + CoA => acetyl-CoA + dodecanedioyl-CoA


name: ADP + H(+) + O-phospho-L-seryl-[isocitrate dehydrogenase] => ATP + L-seryl-[isocitrate dehydrogenase]


name: alliin = 2-aminoprop-2-enoate + allylsulfenate


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Gallus gallus)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Caenorhabditis elegans)


name: AURKA phosphorylates PHLDA1 (Rattus norvegicus)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 + reduced [NADPH--hemoprotein reductase] => (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]


name: acetyl phosphate + H(+) + sulfite => phosphate + sulfoacetaldehyde


name: 2-acyl LPS is acylated to PS by LPSAT (Mus musculus)


name: ethylnitronate + O2 => acetaldehyde + chemical entity + H(+) + nitrite


name: KDM5A-D demethylate Me2K5-histone H3 (Sus scrofa)


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Mus musculus)


name: H(+) + NADPH + O2 + theophylline => 3-methylxanthine + formaldehyde + H2O + NADP(+)


name: RAB43:GTP binds USP8NL (Schizosaccharomyces pombe)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-sn-glycerol <=> (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,3-di-(9Z-octadecenoyl)-glycerol


name: 2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen


name: (3S)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2 => N-methyl-L-dopa + O2


name: 3 H2O + 4 oxidized [2Fe-2S]-[ferredoxin] + pentalen-13-al => 4 H(+) + 2 O2 + pentalenene + 4 reduced [2Fe-2S]-[ferredoxin]


name: D-erythrulose 1-phosphate + H(+) + NADPH => D-erythritol 1-phosphate + NADP(+)


name: D-fructose + H(+) + NADH => D-mannitol + NAD(+)


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Gallus gallus)


name: glycine + tetradecanoyl-CoA <=> CoA + H(+) + N-tetradecanoylglycine


name: H(+)(in) + L-tyrosine(in) = H(+)(out) + L-tyrosine(out)


name: acetyl-CoA + AH2 + 3 H(+) + 3 malonyl-CoA <=> A + 3 CO2 + 4 CoA + H2O + orsellinaldehyde


name: Membrane-bound myeloperoxidase (MPO) produces hypochlorous acid (HOCl) (Gallus gallus)


name: Beta-defensins bind microbial membranes causing disruption (Homo sapiens)


name: Gamma-carboxy pro-BGLAP transport from the endoplasmic reticulum to the Golgi apparatus (Bos taurus)


name: an ultra-long-chain di-unsaturated fatty acyl-[ACP] + H(+) + malonyl-[ACP] <=> a 3-oxo-ultra-long-chain di-unsaturated fatty acyl-[ACP] + CO2 + holo-[ACP]


name: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) => acenaphthene-1,2-dione + 2 H(+) + 2 NADPH


name: (2R,3S)-piscidate + (E)-feruloyl-CoA <=> cimicifugate E + CoA


name: JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Rattus norvegicus)


name: 3,3',5-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out) => 3,3',5-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in)


name: RAB43 hydrolyses GTP (Dictyostelium discoideum)


name: Na(+)(out) + uridine(out) = Na(+)(in) + uridine(in)


name: hexadecanoyl-CoA + N-terminal L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester = CoA + H(+) + N-terminal N-hexadecanoyl-L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Canis familiaris)


name: 2 H(+) + NADPH + oxidized coenzyme F420-(gamma-L-Glu)(n) => NADP(+) + reduced coenzyme F420-(gamma-L-Glu)(n)


name: (+)-epi-isozizaene + 2 H(+) + O2 + 2 reduced [2Fe-2S]-[ferredoxin] <=> (5S)-albaflavenol + H2O + 2 oxidized [2Fe-2S]-[ferredoxin]


name: Epsin family proteins bind ubiquitinated cargo (Homo sapiens)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain) -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) (Canis familiaris)


name: SMURF2 ubiquitinates SMAD2 (Mus musculus)


name: (2R,3S)-2,4',7-trihydroxyisoflavanone = daidzein + H(+) + H2O


name: Transport of L1 into endosomes (Bos taurus)


name: Interaction of IRF9 with p-STAT2:p-STAT1 (Mus musculus)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Canis familiaris)


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Bos taurus)


name: LC3:ATG7 dimer binds ATG3 (Rattus norvegicus)


name: (7R,8S)-8-amino-7-(carboxyamino)nonanoate + ATP => (4R,5S)-dethiobiotin + ADP + H(+) + phosphate


name: alpha-D-Abe-(1->3)-alpha-L-Rha2OAc-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP + H(+) => alpha-L-2OAcRha-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Gal-di-trans,octa-cis-undecaprenyl diphosphate + CDP-alpha-D-abequose


name: Recruitment of PLC-gamma to SLP-76 and p-5Y-LAT (Mus musculus)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + cholesterol <=> an N-acylsphing-4-enine + cholesteryl 3-beta-D-galactoside


name: The high affinity receptor complex binds to G-protein (Sus scrofa)


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O = 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + H(+) + phosphate


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Danio rerio)


name: 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine => beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GalpNAc + H2O


name: CUL9:RBX1 ubiquitinates BIRC5 (Bos taurus)


name: atROL binds to RBP2 (Xenopus tropicalis)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Homo sapiens)


name: PCK1 phosphorylates OA to yield PEP (Caenorhabditis elegans)


name: ACP phosphopantetheine attachment site binding


name: 2 a 1,4-benzosemiquinone + NADP(+) => 2 a quinone + H(+) + NADPH


name: SMG6 hydrolyzes mRNA with premature termination codon (Danio rerio)


name: H2O + N(2)-(4-aminobutanoyl)-L-ornithine <=> 4-aminobutanoate + L-ornithine


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Rattus norvegicus)


name: ADP + dimethylallyl diphosphate => diphosphate + N(6)-(dimethylallyl)adenosine 5'-diphosphate


name: Platelet-derived TREM-1 ligand binds to TREM-1 (Canis familiaris)


name: Thrombin-activated PARs binds G-protein Gq (Homo sapiens)


name: Fe(III)-[cytochrome c] + H2O + nitric oxide = Fe(II)-[cytochrome c] + 2 H(+) + nitrite


name: 3,4-dimethylbenzyl alcohol + O2 <=> 3,4-dimethylbenzaldehyde + H2O2


name: LIPH, I hydrolyse PA to 2-acyl LPA (Danio rerio)


name: dimethylallyl diphosphate + tardioxopiperazine A <=> diphosphate + variecolorin L


name: chloride(out) + Cs(+)(in) + 2 hydrogencarbonate(in) => chloride(in) + Cs(+)(out) + 2 hydrogencarbonate(out)


name: 3-hydroxypropanoate + ATP + CoA <=> 3-hydroxypropanoyl-CoA + AMP + diphosphate


name: PTPN18 binds ERBB2:EGFR heterodimers (Mus musculus)


name: 3-oxohexadecanoyl-[ACP] + H(+) + NADPH => (3R)-hydroxyhexadecanoyl-[ACP] + NADP(+)


name: CYSLTR1 binds CYSLTR1 antagonists (Canis familiaris)


name: CYB5Rs reduce MetHb to HbA (Homo sapiens)


name: GDIs block activation of RHOC (Homo sapiens)


name: YWHAB dimer dissociates from dephosphorylated RAF (Homo sapiens)


name: H2O + kynurenate + L-phenylalanine => 3-phenylpyruvate + L-kynurenine


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Xenopus tropicalis)


name: F2R:ARRB2 binds MAPKs, SRC-1 (Canis familiaris)


name: H2O + N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] => N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate


name: (9Z)-tetradecenoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in) => (9Z)-tetradecenoate(out) + ATP(in) + CoA(in) + H(+)(out)


name: 6-carboxy-5,6,7,8-tetrahydropterin + H(+) => 7-carboxy-7-deazaguanine + NH4(+)


name: CDK1 phosphorylates VCPIP1 (Gallus gallus)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains (Mus musculus)


name: 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(10Z-heptadecenoyl)-sn-glycerol + 9-(10Z-heptadecenoyloxy)-octadecanoate


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Drosophila melanogaster)


name: BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Bos taurus)


name: a ganglioside GM2 (d18:1(4E)) + H2O <=> a ganglioside GM3 (d18:1(4E)) + N-acetyl-beta-D-galactosamine


name: beta-D-galactosyl-(1->4)-L-rhamnose + phosphate => alpha-D-galactose 1-phosphate + L-rhamnopyranose


name: (S)-dihydroorotate + a menaquinone <=> a menaquinol + orotate


name: 2 hydrogencarbonate(out) + sulfate(in) => 2 hydrogencarbonate(in) + sulfate(out)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Gallus gallus)


name: ATP + dGMP + L-aspartate = (2S)-2-amino-2'-deoxyadenylo-succinate + ADP + 2 H(+) + phosphate


name: (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 3,6-anhydro-L-galactonate + 2 H(+) + NADH => 3,6-anhydro-alpha-L-galactopyranose + H2O + NAD(+)


name: HSP90 binds TBK1 and IRF3 (Homo sapiens)


name: SULT1A1 dimer sulfonates NHABP (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Rattus norvegicus)


name: benzaldehyde + H2O2 => benzyl alcohol + O2


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Homo sapiens)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Canis familiaris)


name: SUMOylation of DDX17 with SUMO1 (Sus scrofa)


name: an acyl-CoA + sn-glycerol 3-phosphocholine <=> a monoacyl-sn-glycero-3-phosphocholine + CoA


name: Fusion of COPII vesicle with Golgi complex (Mus musculus)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: Mitochondrial BTD hydrolyses BCTN (Danio rerio)


name: diphosphate + neryl diphosphate => dimethylallyl diphosphate + isopentenyl diphosphate


name: 2 H(+)(out) + 3 menaquinol-8(in) + nitrite(out) => 2 H2O(out) + 3 menaquinone-8(in) + NH4(+)(out)


name: ST6GALNAC2 transfers sialic acid to Core 1 mucins (Mus musculus)


name: DCA binds PDK2 (Schizosaccharomyces pombe)


name: 1,2-dihydro-beta-NADP + H(+) + O2 = H2O2 + NADP(+)


name: coproporphyrinogen III + 2 S-adenosyl-L-methionine <=> 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX


name: 2 mycothiol + NADP(+) => H(+) + mycothione + NADPH


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Mus musculus)


name: Caspase-mediated cleavage of Lamin A (Bos taurus)


name: Formation of the MCC complex (Mus musculus)


name: TREX1 binds retroviral-derived DNA (Homo sapiens)


name: NOD1 induced apoptosis is mediated by RIP2 and CARD8 (Rattus norvegicus)


name: IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Gallus gallus)


name: H(+)(out) + L-proline(out) = H(+)(in) + L-proline(in)


name: Calcium Binds Caldesmon (Drosophila melanogaster)


name: glutamine + H2O => glutamate + NH4+ [GLS] (Canis familiaris)


name: MRN recruits LIG3:XRCC1 to MMEJ sites (Gallus gallus)


name: Phosphorylated LEPR Binds SOCS3 (Homo sapiens)


name: TYRP1 oxidises DHICA to IQCA (Caenorhabditis elegans)


name: (R)-5-methyl-tetronate + o-quinone methide = peniphenone D


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Rattus norvegicus)


name: (3R)-citramalyl-CoA + succinate => (3R)-citramalate + succinyl-CoA


name: D-alanine(in) + H(+)(in) = D-alanine(out) + H(+)(out)


name: Elongating transcript encounters a lesion in the template (Homo sapiens)


name: JAK2 phosphorylation of GHR (Mus musculus)


name: Secretion and activation of the latent large complex of TGF-beta-1 (Rattus norvegicus)


name: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) <=> diphosphate + DNA(n+1)


name: H2O + N-tetracosanoylsphinganine = sphinganine + tetracosanoate


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Rattus norvegicus)


name: H(+) + NADPH + tropinone => NADP(+) + tropine


name: 2 2-iminio-3-(indol-3-yl)propanoate + H2O2 <=> 2 H2O + indole-3-pyruvate imine dimer


name: L-methionine(in) + S-methylmercury-L-cysteine(out) = L-methionine(out) + S-methylmercury-L-cysteine(in)


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Rattus norvegicus)


name: FUOM isomerises alpha-Fuc to beta-Fuc (Rattus norvegicus)


name: arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate (Homo sapiens)


name: 1-octanoyl-3-(9Z-octadecenoyl)-glycerol + CoA => (9Z)-octadecenoyl-CoA + 1-octanoylglycerol


name: H2O + N-terminal N(alpha)-acetyl-L-cysteinyl-L-aspartyl-[protein] <=> N-acetyl-L-cysteine + N-terminal L-aspartyl-[protein]


name: [DsbA protein]-dithiol + [DsbB protein]-disulfide <=> [DsbA protein]-disulfide + [DsbB protein]-dithiol


name: Caspase-mediated cleavage of Rock-1 (Caenorhabditis elegans)


name: AH2 + O2 + progesterone <=> A + H2O + testosterone acetate


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Homo sapiens)


name: (2R,3S)-3-methylmalate + NAD(+) = 3-carboxy-2-oxobutanoate + H(+) + NADH


name: ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Gallus gallus)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Caenorhabditis elegans)


name: AMP + guanosine 3'-diphosphate 5'-triphosphate => ATP + GTP


name: (9Z,12Z,15Z)-octadecatrienoate + O2 <=> (11S)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate


name: 2-aminoisobutanoate(in) + L-alanine(out) => 2-aminoisobutanoate(out) + L-alanine(in)


name: H(+)(in) + L-serine(in) <=> H(+)(out) + L-serine(out)


name: H2O + NADP(+) + senecionine N-oxide => NADPH + O2 + senecionine


name: L1 interaction with Integrins (Rattus norvegicus)


name: 2 H2O + NH4(+) + 6 oxidized [2Fe-2S]-[ferredoxin] = 8 H(+) + nitrite + 6 reduced [2Fe-2S]-[ferredoxin]


name: an anthocyanidin with a 3-hydroxy group + 2 H(+) + 2 NADPH => a (2S,3R)-flavan-3-ol + 2 NADP(+)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA + holo-[ACP] => a fatty acyl-[ACP] + an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA


name: GDP-valienol + validamine 7-phosphate = GDP + H(+) + validoxylamine A 7'-phosphate


name: VEGFA-165 dimer binds VEGFA inhibitors (Homo sapiens)


name: PSMD14 cleaves K63-linked ubiquitin (Xenopus tropicalis)


name: ADP(out) + FMN(in) => ADP(in) + FMN(out)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(in) <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)(out)


name: DNA polymerase epsilon binds at the origin (Plasmodium falciparum)


name: 6-hydroxynicotinate + H2O + O2 => 2,6-dihydroxynicotinate + H2O2


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) (Gallus gallus)


name: Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Gallus gallus)


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Canis familiaris)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Canis familiaris)


name: reduced coenzyme F420:heterodisulfide oxidoreductase activity


name: CYP2C19 5-hydroxylates omeprazole (Homo sapiens)


name: ATP + H2O + kainate(in) => ADP + H(+) + kainate(out) + phosphate


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Mus musculus)


name: UDP-alpha-D-glucuronate(in) + UDP-N-acetyl-alpha-D-galactosamine(out) => UDP-alpha-D-glucuronate(out) + UDP-N-acetyl-alpha-D-galactosamine(in)


name: enterobactin + UDP-alpha-D-glucose => monoglucosyl-enterobactin + UDP


name: Dissociation of the TP:Gq complex (Gallus gallus)


name: CoA + H(+) + N-octadecanoyl-sphinga-4E,14Z-dienine => octadecanoyl-CoA + sphinga-4E,14Z-dienine


name: 17-hydroxylupanine + 2 Fe(II)-[cytochrome c] + 2 H(+) => 2 Fe(III)-[cytochrome c] + H2O + lupanine


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Caenorhabditis elegans)


name: eIF3 and eIF1A bind to the 40S subunit (Bos taurus)


name: 2-methylfumaryl-CoA + reduced [electron-transfer flavoprotein] => (2S)-methylsuccinyl-CoA + H(+) + oxidized [electron-transfer flavoprotein]


name: MITF-M and CTNNB1-dependent CCND1 expression (Homo sapiens)


name: TP53INP1 and HIPK2 bind TP53 (Sus scrofa)


name: (R)-lavandulol + diphosphate => (R)-lavandulyl diphosphate + H2O


name: Ca permeable AMPA receptor ligand binding (Canis familiaris)


name: cytidine 2'-phosphate + H2O => cytidine + phosphate


name: HIPK2 phosphorylates RUNX1 and EP300 (Homo sapiens)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Drosophila melanogaster)


name: RAC1:GTP binds NOX1 complex (Canis familiaris)


name: cadaverine + H2O + O2 = 5-aminopentanal + H2O2 + NH4(+)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine => a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + H(+) + UDP


name: IRAK1 binds to MYD88 within the IL1R complex (Canis familiaris)


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Sus scrofa)


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Danio rerio)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Drosophila melanogaster)


name: Cleavage of DNA by DFF40 (Canis familiaris)


name: Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Rattus norvegicus)


name: (2E)-geranial + H2O + NAD(+) => geranate + 2 H(+) + NADH


name: GPX7,8 catalyze peroxidation of P4HB (PDI) (Gallus gallus)


name: geranylgeranyl diphosphate + 7 isopentenyl diphosphate <=> 7 diphosphate + tri-trans,hepta-cis-undecaprenyl diphosphate


name: 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity


name: Exocytosis of ficolin-rich granule lumen proteins (Xenopus tropicalis)


name: Dopamine is oxidised to noradrenaline (Bos taurus)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Bos taurus)


name: FAAH2 hydrolyses AEA to AA and ETA (Xenopus tropicalis)


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Mus musculus)


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Dictyostelium discoideum)


name: RAB33B:GTP binds RIC1:RGP1 (Homo sapiens)


name: Mcm2-7 is phosphorylated by DDK (Schizosaccharomyces pombe)


name: H(+) + N-methylethanolamine phosphate + S-adenosyl-L-homocysteine => phosphoethanolamine + S-adenosyl-L-methionine


name: 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+) => 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP


name: SORD oxidizes D-sorbitol to Fru (Schizosaccharomyces pombe)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Schizosaccharomyces pombe)


name: a 1-tetracosanoyl-2-acyl-phosphoglycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a 1-[(15Z)-tetracos-15-enoyl]-2-acyl-phosphoglycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: acetyl-CoA + H2O => acetate + CoASH + H+ (Xenopus tropicalis)


name: an L-amino acid tripeptide(in) + H(+)(in) => an L-amino acid tripeptide(out) + H(+)(out)


name: A + decanedioyl-CoA <=> (2E)-decenedioyl-CoA + AH2


name: GAL3ST1 transfers sulfate to GalCer,LacCer (Mus musculus)


name: RAB8 GEFs exchange GTP for GDP on RAB8 (Schizosaccharomyces pombe)


name: Association of HA into rafts (Homo sapiens)


name: (E)-4-coumaroyl-CoA + 2-oxoglutarate + O2 => (E)-2,4-dihydroxycinnamoyl-CoA + CO2 + succinate


name: a flavanone => a (E)-2'-hydroxy-chalcone


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoyl-CoA + 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol <=> 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: PPP1CC dephosphorylates PLK1 (Saccharomyces cerevisiae)


name: 18-HEPE + O2 <=> (5S)-hydroperoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate


name: alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose <=> beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + H(+) + UDP


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Canis familiaris)


name: dodecanoate + H(+) + holo-[ACP] => dodecanoyl-[ACP] + H2O


name: 2-oxobutanoate + methanethiol + NH4(+) => H2O + L-methionine


name: PAOX:FAD oxidises NASPN to SPM (Caenorhabditis elegans)


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Drosophila melanogaster)