label: RSXpSXP Motif
label_lc: rsxpsxp motif
description: "The 14-3-3 family of proteins mediates signal transduction by binding to phosphoserine-containing proteins. RSXpSXP Motif is one of two different binding motifs that are present in nearly all known 14-3-3 binding proteins. The14-3-3 dimer binds tightly to single molecules containing tandem repeats of phosphoserine motifs, implicating bidentate association as a signaling mechanism with molecules such as Raf, BAD, and Cbl. (from OMIM)"