label: Bromodomain
label_lc: bromodomain
description: "A motif common in chromatin remodeling factors. It consists of approximately 110 amino acids in a left-handed up-and-down four helix bundle with a left handed twist. A hydrophobic pocket in the bromodomain creates an acetyl-lysine binding domain. Bromodomain-containing proteins may recruit remodeling complexes to acetylated chromatin regions."