Donor Derived HIV-Specific T-cells with Non-escaped Epitope Targets
donor derived hiv-specific t-cells with non-escaped epitope targets
"A preparation of ex vivo expanded donor-derived (DD) human immunodeficiency virus (HIV)-specific T-cells (HSTs) with non-escaped epitope targets (NEETs), that can potentially be used to eliminate HIV-infected cells and eradicate HIV. Upon administration, DD HST-NEETs target and kill HIV-infected cells, thereby eradicating HIV. HST-NEETs recognize multiple conserved, non-escaped HIV epitopes and their common variants, which is important in killing latently infected cells and could reduce viral escape."