Donor Regulatory T-lymphocytes
donor regulatory t-lymphocytes
"Donor-derived regulatory T-cells (Tregs), with potential immunomodulating activity.  Tregs are a subset of CD4+ T cells that express high levels of CD25 (interleukin 2 receptor) and the transcription factor Foxp3. The donor CD4+CD25+ Tregs modulate immune responses and may induce tolerance to allogeneic organ transplants, such as hematopoietic stem cell transplants (HSCTs), thereby preventing graft-versus-host disease (GVHD)."