label: phosphorothioate oligonucleotide
label_lc: phosphorothioate oligonucleotide
description: "An oligonucleotide in which one of the non-bridging oxygens in each phosphodiester linkage has been replaced by sulfur. The main application of phosphorothioate linkages in an oligonucleotide is to protect the oligonucleotide from nuclease degradation."