label: combined immunodeficiency due to DOCK8 deficiency
label_lc: combined immunodeficiency due to dock8 deficiency
description: "Combined immunodeficiency due to dedicator of cytokinesis 8 protein (DOCK8) deficiency is a form of T and B cell immunodeficiency characterized by recurrent cutaneous viral infections, susceptibility to cancer and elevated serum levels of immunoglobulin E (IgE)."