label: Immunodeficiency 11B with Atopic Dermatitis
label_lc: immunodeficiency 11b with atopic dermatitis
description: "An autosomal dominant condition caused by mutation(s) in the CARD11 gene, encoding caspase recruitment domain-containing protein 11. It is characterized by the onset of moderate to severe atopic dermatitis in early childhood, defects in T-cell activation, increased IgE, and eosinophilia."