label: Low Grade Fibromyxoid Sarcoma
label_lc: low grade fibromyxoid sarcoma
description: "A low-grade, late-metastasizing variant of fibrosarcoma characterized by alternating fibrous and myxoid areas and a whorling growth pattern.  The neoplastic cells have a spindle morphology, and lack hyperchromasia or significant nuclear atypia.  Approximately 40% of cases show the focal presence of collagen rosettes.  A t(7;16)(q33;p11) translocation has been identified in the majority of cases, associated with the presence of FUS-CREB3L2 fusion protein.  Rare cases carry the t(11;16)(p11;p11) translocation which is associated with the presence of the FUS-CREB3L1 fusion protein."