label: Langerhans Cell Sarcoma
label_lc: langerhans cell sarcoma
description: "A neoplastic proliferation of Langerhans cells with overtly malignant cytologic features.  It can be considered a higher grade variant of Langerhans cell histiocytosis (LCH) and it can present de novo or progress from antecedent LCH. (WHO, 2001)"