label: Glucokinase-Associated Diabetes Mellitus
label_lc: glucokinase-associated diabetes mellitus
description: "Monogenic diabetes caused by inactivating mutation(s) in the GCK gene, encoding glucokinase. Heterozygous GCK mutations may manifest as mild hyperglycemia, which is not progressive, and usually requires no treatment. Homozygous GCK mutations result in permanent neonatal diabetes."