label: T-cell immunodeficiency, congenital alopecia, and nail dystrophy
label_lc: t-cell immunodeficiency, congenital alopecia, and nail dystrophy
description: "A severe combined immunodeficiency characterized by congenital alopecia, severe T-cell immunodeficiency, and ridging, pitting or curving of all nails that has material basis in homozygous mutation in the FOXN1 gene on chromosome 17q11-q12."