label: Multicentric Osteolysis, Nodulosis, and Arthropathy
label_lc: multicentric osteolysis, nodulosis, and arthropathy
description: "A rare, autosomal recessive inherited syndrome caused by mutations in the MMP2 gene. It is characterized by the presence of multiple, painless subcutaneous nodules, osteolysis particularly in the hands and feet, osteoporosis, and arthropathy."