label: SWI/SNF Complex-Deficient Sinonasal Carcinoma
label_lc: swi/snf complex-deficient sinonasal carcinoma
description: "A highly aggressive, poorly to undifferentiated carcinoma that arises from the sinonasal tract. It is characterized by loss of one SWI/SNF complex subunit (either SMARCB1 or SMARCA4) and lacks histological features to allow classification into another specific entity. Most patients present with locally advanced disease."