label: Spinal Cord Ependymoma, MYCN Amplified
label_lc: spinal cord ependymoma, mycn amplified
description: "A rare, aggressive ependymoma that arises from the spinal cord. It displays microvascular proliferation, necrosis, and high mitotic rate. It is characterized by high-level MYCN amplification. Cytogenetic abnormalities include loss of chromosome 10 and focal losses on chromosome 11q. The prognosis is poor."