label: vitamin K-dependent clotting factors, combined deficiency of, type 1
label_lc: vitamin k-dependent clotting factors, combined deficiency of, type 1
description: "Combined vitamin K-dependent clotting factors deficiency (VKCFD) is a congenital bleeding disorder resulting from variably decreased levels of coagulation factors II, VII, IX and X, as well as natural anticoagulants protein C, protein S and protein Z."