label: leukoencephalopathy-palmoplantar keratoderma syndrome
label_lc: leukoencephalopathy-palmoplantar keratoderma syndrome
description: "Leukoencephalopathy-palmoplantar keratoderma syndrome is a rare, genetic epidermal disease characterized by early childhood-onset of punctate palmoplantar keratoderma in association with adult-onset leukoencephalopathy manifested by progressive tetrapyramidal syndrome and cognitive deterioration."