label: Myeloid/Lymphoid Neoplasms with JAK2 Rearrangement
label_lc: myeloid/lymphoid neoplasms with jak2 rearrangement
description: "Hematologic neoplasms characterized by the presence of t(8;9)(p22;p24.1) that results in PCM1-JAK2 fusion gene expression. It is associated with eosinophilia, bone marrow findings of left-shifted erythroid predominance, lymphoid aggregates, and often myelofibrosis. Rare cases present as T- or B-acute lymphoblastic leukemia."