label: Hypomyelinating Leukodystrophy-6
label_lc: hypomyelinating leukodystrophy-6
description: "A genetic disorder of infancy or early childhood caused by mutation(s) in the TUBB4A gene, encoding the tubulin beta-4A chain. It is characterized by hypomyelination or atrophy of the cerebellum and or putamen leading to delayed motor development, gait instability, and extrapyramidal movement disorders."