label: Primary Bone Non-Hodgkin Lymphoma
label_lc: primary bone non-hodgkin lymphoma
description: "A non-Hodgkin lymphoma that arises from the bone, without lymph node or other extranodal involvement.  The femur, spine, and pelvic bones are the most frequently affected areas.  The majority of cases are diffuse large B-cell lymphomas.  Most patients present with pain in the affected area.  Systemic symptoms are rare."