label: Primary Mediastinal Large B-Cell Lymphoma
label_lc: primary mediastinal large b-cell lymphoma
description: "A large B-cell non-Hodgkin lymphoma arising in the mediastinum.  Morphologically it is characterized by a massive diffuse lymphocytic proliferation associated with compartmentalizing fibrosis.  Response to intensive chemotherapy, with or without radiotherapy, is usually good. (WHO, 2001)"