label: Anaplastic Large Cell Lymphoma, ALK-Positive
label_lc: anaplastic large cell lymphoma, alk-positive
description: "A T-cell peripheral lymphoma composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm. It is characterized by the presence of a translocation involving the ALK gene and expression of ALK fusion protein. Most patients present with peripheral and/or abdominal lymphadenopathy, and often have advanced disease and extranodal involvement."