label: High Risk Chronic Myelomonocytic Leukemia
label_lc: high risk chronic myelomonocytic leukemia
description: "Chronic myelomonocytic leukemia with cytogenetic abnormalities including trisomy 8, complex karyotypes, monosomy 7, and del17q. Mutations in RUNX1, NRAS, SETBP1, and ASXL1 are independently associated with inferior overall survival time. (Oncology Letters 15:7132-7138, 2018)"