label: Hereditary Nonpolyposis Colorectal Cancer Syndrome
label_lc: hereditary nonpolyposis colorectal cancer syndrome
description: "An inherited syndrome characterized by the development of several cancers, particularly colon and rectal cancers.  It includes Lynch syndrome which is associated with germline mutations in DNA mismatch-repair genes and familial colorectal cancer type X which is characterized by the absence of germline mutations in DNA mismatch-repair genes."