label: Primary Oral Cavity CD30-Positive T-Cell Lymphoproliferative Disorder
label_lc: primary oral cavity cd30-positive t-cell lymphoproliferative disorder
description: "A spectrum of T-cell lymphoproliferative disorders that arise from the oral mucosa and are characterized by the presence of CD30-positive neoplastic lymphoid cells with pleomorphic nuclei and abundant cytoplasm. Cells that resemble the hallmark cells of anaplastic large cell lymphoma are often seen. The lesions arise from the gingiva, buccal mucosa, tongue, and palate. Patients usually present with a mass that is often ulcerated. In most cases complete remission is achieved, following excision, with or without radiotherapy, and with or without systemic chemotherapy."