label: Mendelian susceptibility to mycobacterial diseases due to complete IFNgammaR1 deficiency
label_lc: mendelian susceptibility to mycobacterial diseases due to complete ifngammar1 deficiency
description: "Mendelian susceptibility to mycobacterial diseases (MSMD) due to complete interferon gamma receptor 1 (IFN-gammaR1) deficiency is a genetic variant of MSMD characterized by a complete deficiency in IFN-gammaR1, leading to impaired IFN-gamma immunity and, consequently, to severe and often fatal infections with bacillus Calmette-GuC)rin (BCG) and other environmental mycobacteria (EM)."