label: neurodevelopmental disorder with severe motor impairment and absent language
label_lc: neurodevelopmental disorder with severe motor impairment and absent language
description: "A complex neurodevelopmental disorder caused by variation in DHX30. Individuals with variants in DHX30 have been found to have variable presentations including intellectual development, delayed or absent speech development, delayed motor development, hypotonia, feeding difficulties, and ataxic gait or the inability to walk. Other phenotypic features commonly reported include sleep disorders, autistic features, seizures, and joint hypermobility"