label: Differentiated Penile Intraepithelial Neoplasia, Human Papillomavirus-Independent
label_lc: differentiated penile intraepithelial neoplasia, human papillomavirus-independent
description: "Intraepithelial neoplasia of the penis that is not caused by human papillomavirus infection. It usually presents as a solitary white or pink macule or plaque that may be slightly elevated. A background of long-standing lichen sclerosus is often present. It is characterized by a thickened epithelium, subtle abnormal cellular maturation, and atypical basal layer cells. Parakeratosis is common. (WHO 2016)"