label: X-Linked Immunodeficiency with Magnesium Defect, Epstein-Barr Virus Infection and Neoplasia
label_lc: x-linked immunodeficiency with magnesium defect, epstein-barr virus infection and neoplasia
description: "An X-linked recessive condition caused by mutation(s) in the MAGT1 gene, encoding magnesium transporter protein 1. It is characterized by CD4 lymphopenia, defective T-cell activation and susceptibility to severe chronic viral infections, particularly Epstein-Barr virus (EBV), which may lead to the development of EBV-associated B-cell lymphoproliferative disorders."