label: histone H2B C-terminal K residue ubiquitin ligase activity
label_lc: histone h2b c-terminal k residue ubiquitin ligase activity
description: "Catalysis of the transfer of a ubiquitin molecule to a histone 2B at the conserved C-terminal lysine (K) residue. The last K residue is at position 119 in fission yeast, 123 in budding yeast, and 120 in mammals."