label: NAD+ nucleotidase, cyclic ADP-ribose generating
label_lc: nad+ nucleotidase, cyclic adp-ribose generating
description: "Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose, in a two steps reaction: first an ADP-ribosyl cyclase reaction, followed by a cyclic ADP-ribose hydrolase reaction."