label: Gi/o-coupled serotonin receptor activity
label_lc: gi/o-coupled serotonin receptor activity
description: "Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels."