label: 4-hydroxymuconic-semialdehyde dehydrogenase activity
label_lc: 4-hydroxymuconic-semialdehyde dehydrogenase activity
description: "Catalysis of the reaction: <stereo>cis,trans</stereo>-4-hydroxymuconate semialdehyde + H2O + NAD+ = 2 H+ + maleylacetate + NADH."