label: a C27-steroid + reduced [NADPH--hemoprotein reductase] + O2 = a (22S)-22-hydroxy C27-steroid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
label_lc: a c27-steroid + reduced [nadph--hemoprotein reductase] + o2 = a (22s)-22-hydroxy c27-steroid + oxidized [nadph--hemoprotein reductase] + h2o + h(+)