label: tRNA (guanine(18)-2'-O)-methyltransferase activity
label_lc: trna (guanine(18)-2'-o)-methyltransferase activity
description: "Catalysis of the reaction: S-adenosyl-L-methionine + guanosine 18 in tRNA= S-adenosyl-L-homocysteine + 2'-O-methylguanosine 18 in tRNA + H+."