label: 2-hydroxyestrone + S-adenosyl-L-methionine = 2-hydroxy-3-methoxy-estrone + S-adenosyl-L-homocysteine + H(+)
label_lc: 2-hydroxyestrone + s-adenosyl-l-methionine = 2-hydroxy-3-methoxy-estrone + s-adenosyl-l-homocysteine + h(+)