label: hypoxia-inducible factor-proline dioxygenase activity
label_lc: hypoxia-inducible factor-proline dioxygenase activity
description: "Catalysis of the reaction: 2-oxoglutarate + L-prolyl-[hypoxia-inducible factor alpha subunit] + O2 = CO2 + succinate + trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit]."