label: estradiol 17-beta-dehydrogenase [NAD(P)+] activity
label_lc: estradiol 17-beta-dehydrogenase [nad(p)+] activity
description: "Catalysis of the reaction: estradiol-17-beta + NAD(P)+ = estrone + NAD(P)H + H+. The activity can use NAD+ or NADP+ as the acceptor."