label: 4-hydroxy-17beta-estradiol + S-adenosyl-L-methionine = 4-methoxy-17beta-estradiol + S-adenosyl-L-homocysteine + H(+)
label_lc: 4-hydroxy-17beta-estradiol + s-adenosyl-l-methionine = 4-methoxy-17beta-estradiol + s-adenosyl-l-homocysteine + h(+)