label: 25-hydroxycholesterol 7alpha-hydroxylase activity
label_lc: 25-hydroxycholesterol 7alpha-hydroxylase activity
description: "Catalysis of the reactions: 25-hydroxycholesterol + O2 + reduced [NADPH--hemoprotein reductase] = 7alpha,25-dihydroxycholesterol + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. Also converts (25R)-cholest-5-ene-3beta,26-diol to (25R)-cholest-5-en-3beta,7alpha,26-triol."