label: very long-chain-3-hydroxyacyl-CoA dehydrogenase activity
label_lc: very long-chain-3-hydroxyacyl-coa dehydrogenase activity
description: "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid has an aliphatic tail containing more than 22 carbons."