label: 1D-myo-inositol 1,4,5-trisphosphate + ATP <=> 1D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + H(+)
label_lc: 1d-myo-inositol 1,4,5-trisphosphate + atp <=> 1d-myo-inositol 1,4,5,6-tetrakisphosphate + adp + h(+)