label: (2R)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 3 S-adenosyl-L-homocysteine + 8 CO2 + diphosphate + 8 NADP(+) + 8 CoA + 6 H2O => (2S,4R)-4-hydroxy-4-methylglutamate + 8 malonyl-CoA + 3 S-adenosyl-L-methionine + ATP + 8 NADPH + 11 H(+)
label_lc: (2r)-3-[(2s)-3,5-dioxo-4-[(2e,4r,6r,8e,10e,12e)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + amp + 3 s-adenosyl-l-homocysteine + 8 co2 + diphosphate + 8 nadp(+) + 8 coa + 6 h2o => (2s,4r)-4-hydroxy-4-methylglutamate + 8 malonyl-coa + 3 s-adenosyl-l-methionine + atp + 8 nadph + 11 h(+)