label: very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity
label_lc: very-long-chain (3r)-3-hydroxyacyl-coa dehydratase activity
description: "Catalysis of the reaction: a very-long-chain (3R)-3-hydroxyacyl-CoA = H2O + a very-long-chain (2E)-enoyl-CoA. This reaction is the third (dehydration) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit."