label: RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending
label_lc: rna polymerase ii cis-regulatory region sequence-specific dna binding, bending
description: "Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II, and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence."