label: 2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine => 2-hydroxy-3-methoxy-17beta-estradiol + S-adenosyl-L-homocysteine + H(+)
label_lc: 2-hydroxy-17beta-estradiol + s-adenosyl-l-methionine => 2-hydroxy-3-methoxy-17beta-estradiol + s-adenosyl-l-homocysteine + h(+)