label: tRNA-4-demethylwyosine synthase activity
label_lc: trna-4-demethylwyosine synthase activity
description: "Catalysis of the reaction: pyruvate + S-adenosyl-L-methionine + N1-methylguanine37 in tRNAPhe = L-methionine + 5'-deoxyadenosine + carbon dioxide + H2O + 4-demethylwyosine37 in tRNAPhe."