preferred_name: orotate(in) + nicotinate(out) => orotate(out) + nicotinate(in)
preferred_name_lc: orotate(in) + nicotinate(out) => orotate(out) + nicotinate(in)
label: orotate(in) + nicotinate(out) => orotate(out) + nicotinate(in)
label_lc: orotate(in) + nicotinate(out) => orotate(out) + nicotinate(in)