label: Diminished acetyl-CoA C-acyltransferase activity in cultured fibroblasts
label_lc: diminished acetyl-coa c-acyltransferase activity in cultured fibroblasts
description: "Concentration or activity of acetyl-CoA C-acyltransferase (EC 2.3.1.16) as measured in cultured fibroblasts is below the limits of normal. This enzyme catalyzes the reaction acetyl-CoA + an acyl-CoA = a 3-oxoacyl-CoA + CoA. It is also known as 3-ketoacyl-CoA thiolase and beta-ketothiolase."