label: DDX41-Related Predisposition to Leukemia
label_lc: ddx41-related predisposition to leukemia
description: "An autosomal dominant condition caused by mutation(s) in the DDX41 gene, encoding probable ATP-dependent RNA helicase DDX41. It is characterized by an increased risk of developing hematologic malignancies, including myeloid and lymphoid leukemias and lymphoma."