label: Recurrence of CHAARTED High Volume Metastatic Disease
label_lc: recurrence of chaarted high volume metastatic disease
description: "A recurrence of high volume metastatic disease as defined by the CHAARTED Study (Chemohormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer) as four or more bone metastases with at least one outside the axial skeleton, or the presence of visceral metastases."