label: Hemoglobin Beta Heterozygous Hemoglobin E Plus Insufficiency Genotype
label_lc: hemoglobin beta heterozygous hemoglobin e plus insufficiency genotype
description: "A genetic finding indicating that one copy of chromosome 16 has a hemoglobin beta gene (HBB) with mutations that lead to hemoglobin subunit beta insufficiency (B+) and the other copy has an HBB mutation that produces a hemoglobin subunit beta variant, the hemoglobin beta E variant, where the glutamic acid residue at position 27 has been replaced by lysine (BE). This genotype is associated with beta thalassemia intermedia."