name: tRNA pseudouridine(38-40) synthase activity


name: Arachidonate is epoxidated to 8,9-EET by CYP(5) (Mus musculus)


name: XIAP dissociates from ub-TLE (Sus scrofa)


name: GHRH receptor binds GHRH (Rattus norvegicus)


name: N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-alpha-D-galactosaminyl-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-tri-trans,heptacis-undecaprenyl diphosphate + 3 UDP-N-acetyl-alpha-D-galactosamine => [alpha-D-GalNAc-(1->4)]4-alpha-D-GalNAc-(1->3)-alpha-D-diNAcBac-tri-trans,hepta-cis-undecaprenyl diphosphate + 3 UDP + 3 H(+)


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H2O + H(+) => Fe(III)-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2 + N-(2,3-dihydroxybenzoyl)-L-serine


name: 4-methylcatechol + CO2 => 3,4-dihydroxyphenylacetate + H(+)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA => 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA


name: (E)-4-coumarate + NADH + H(+) => phloretate + NAD(+)


name: sphinganine + hexadecanoate => N-hexadecanoylsphinganine + H2O


name: ITCH polyubiquitinates TP73 (Rattus norvegicus)


name: Formation of VAF (virus-activated factor) complex (Rattus norvegicus)


name: chrodrimanin C + NADPH + O2 + H(+) => chrodrimanin H + NADP(+) + H2O


name: 1-hydroxy-2-naphthoate + NADPH + O2 + 2 H(+) => naphthalene-1,2-diol + CO2 + NADP(+) + H2O


name: (2R,3S)-iso(homo)3citrate + NAD(+) = 2-oxosuberate + CO2 + NADH


name: L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-methionine => N(6),N(6),N(6)-trimethyl-L-lysyl(79)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: Polyubiquitination of substrate (Danio rerio)


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Gallus gallus)


name: SHPRH polyubiquitinates monoubiquitinated PCNA (Canis familiaris)


name: 2-oxopentanoate + L-kynurenine <=> L-2-aminopentanoate + kynurenate + H2O


name: HMOX1 dimer, HMOX2 cleave heme (Danio rerio)


name: ARSA removes sulfate from PSAP(195-273):Sulfatide (Mus musculus)


name: (2E,6E)-farnesyl diphosphate = beta-bisabolene + diphosphate


name: GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Danio rerio)


name: regulation of p-nitrophenol UDP-glucuronyltransferase activity


name: PXLP-K56-SRR dimer deaminates L-Ser (Rattus norvegicus)


name: pimelyl-[acyl-carrier protein] methyl ester esterase activity


name: RHOQ binds effectors at the plasma membrane (Dictyostelium discoideum)


name: diphosphate + H2O <=> 2 phosphate + H(+)


name: Neurofascin interacts with syntenin-1 (Mus musculus)


name: fumigaclavine A + CoA => fumigaclavine B + acetyl-CoA


name: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = an (11E)-Delta(11)-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Sus scrofa)


name: D-isoleucine(out) + D-serine(in) => D-isoleucine(in) + D-serine(out)


name: pentanoyl-CoA + L-seryl-[protein] <=> O-pentanoyl-L-seryl-[protein] + CoA


name: N-(9Z-octadecenoyl)-(4R)-hydroxysphinganine + H2O => (4R)-hydroxysphinganine + (9Z)-octadecenoate


name: 3-hydroxyoctadecanoyl-CoA + NAD(+) = 3-oxooctadecanoyl-CoA + NADH + H(+)


name: 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6)  to yield 45S pre-rRNA (Bos taurus)


name: eicosanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z)-eicosenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (S)-malyl alpha-D-glucosaminide + L-cysteine => bacillithiol + H2O


name: ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Caenorhabditis elegans)


name: Activation of MMP9 intermediate form by MMPs (Xenopus tropicalis)


name: 3-methylbutanal + NAD(+) + H2O => 3-methylbutanoate + NADH + 2 H(+)


name: cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Gallus gallus)


name: tellurite(in) + Na(+)(in) => tellurite(out) + Na(+)(out)


name: a long-chain fatty aldehyde + NAD(+) + H2O => a long-chain fatty acid + NADH + 2 H(+)


name: TRAF2:cIAP1/2 complex binds FN14:TWEAK (Mus musculus)


name: Caspase mediated cleavage of APC (Drosophila melanogaster)


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Mus musculus)


name: PIAS2-2 SUMOylates SUZ12 with SUMO1 (Homo sapiens)


name: butanal + NADP(+) + H2O = butanoate + NADPH + 2 H(+)


name: (9Z,12Z)-octadecadienoate + O2 <=> (11R)-hydroperoxy-(9Z,12Z)-octadecadienoate


name: 16-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2


name: RNF181 binds BCL10 and Ubiquitin:E2 (Bos taurus)


name: ROCK activation by RHO (Caenorhabditis elegans)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-alanine + O2 + H2O <=> 2-dehydro-D-glucose + L-alanine + H2O2


name: IL37(?-218) binds p-S423,S425-SMAD3 (Canis familiaris)


name: L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H2O <=> sn-glycero-3-phospho-L-serine + hexadecanoate + H(+)


name: Nuclear translocation of p38 MAPK (Bos taurus)


name: alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + CMP-N-acetyl-beta-neuraminate = alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc + CMP + H(+)


name: (8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: heme b + 3 AH2 + 3 O2 + 3 H(+) <=> biliverdin IXdelta + CO + Fe(2+) + 3 A + 3 H2O


name: ERK1/2 phosphorylates MSK1 (Dictyostelium discoideum)


name: NSL acetylates histone H4 (Rattus norvegicus)


name: PM20D1 hydrolyzes oleoyl-phe (Bos taurus)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Bos taurus)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [cytosolic] (Sus scrofa)


name: (22S)-22-hydroxy-campesterol C-23 hydroxylase activity


name: JMJD4:Fe2+ hydroxylates a lysine residue of ETF1 (Drosophila melanogaster)


name: dolichol-phosphate-mannose synthase regulator activity


name: an alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+) => an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate


name: Casein kinase II phosphorylates STARD10 (Mus musculus)


name: dTDP-4-O-demethyl-beta-L-noviose + novobiocic acid <=> desmethyldescarbamoylnovobiocin + dTDP + H(+)


name: nitric oxide + Fe(III)-[cytochrome c] + H2O = Fe(II)-[cytochrome c] + nitrite + 2 H(+)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Saccharomyces cerevisiae)


name: 2-hydroxy-5-methylquinone + nitrite + NAD(+) + H2O + H(+) => 4-methyl-5-nitrocatechol + NADH + O2


name: 4 porphobilinogen + H2O => hydroxymethylbilane + 4 NH3 (Gallus gallus)


name: alpha-ribazole 5'-phosphate + adenosylcob(III)inamide-GDP = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)


name: MITF-M binds CREBBP,EP300 (Mus musculus)


name: butanal + NADP(+) + H2O => butanoate + NADPH + 2 H(+)


name: a globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a globoside Gb4Cer (d18:1(4E)) + UDP + H(+)


name: an N(2)-acyl-L-glutamine + H2O = a carboxylate + L-glutamine


name: 5alpha-androstan-3,17-dione + NADPH + H(+) => 17beta-hydroxy-5alpha-androstan-3-one + NADP(+)


name: GTSE1 binds microtubule lattice in interphase cells (Homo sapiens)


name: (5Z)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) => (2E,5Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: N(6)-(3-O-phospho-D-erythrulosyl)-L-lysine + ADP + H(+) => N(6)-(D-erythrulosyl)-L-lysine + ATP


name: oleanolate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+) => beta-amyrin + 3 reduced [NADPH--hemoprotein reductase] + 3 O2


name: glutamine-fructose-6-phosphate transaminase (isomerizing) activity


name: arginine + H2O => ornithine + urea [ARG2] (Caenorhabditis elegans)


name: Interaction of integrin alphaIIbbeta3 with Fibronectin (Rattus norvegicus)


name: N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O = 4-amino-5-aminomethyl-2-methylpyrimidine + formate


name: (9Z)-octadecenoate + O2 => (2R,9Z)-2-hydroperoxyoctadecenoate


name: dTMP + NADP(+) + H2O => dUMP + formaldehyde + NADPH + H(+)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 <=> 10-hydroperoxy-(4Z,7Z,11E,13Z,16Z,19Z)-docosahexaenoate


name: CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Gallus gallus)


name: L-aspartate 4-semialdehyde + NAD(+) + H2O = L-aspartate + NADH + 2 H(+)


name: a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate => a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> stellata-2,6,19-triene + diphosphate


name: versicolorin B + NADPH + O2 + H(+) => versicolorin A + NADP(+) + 2 H2O


name: bisphenol A + NADH + O2 + H(+) => 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD(+) + H2O


name: xylitol + NAD(+) => D-xylose + NADH + H(+)


name: glucosaminyl-PI + fatty acyl-CoA -> glucosaminyl-acyl-PI + CoA-SH (Rattus norvegicus)


name: SGCG,SGCZ and SGCA, SGCE bind SGCB:SGCD (Canis familiaris)


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Sus scrofa)


name: 3-methylbutanoyl-CoA + H2O <=> 3-methylbutanoate + CoA + H(+)


name: PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Sus scrofa)


name: ISGylation of protein translation regulator 4EHP (Dictyostelium discoideum)


name: 26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Xenopus tropicalis)


name: hexadecanoate + holo-[ACP] + ATP <=> hexadecanoyl-[ACP] + AMP + diphosphate


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Dictyostelium discoideum)


name: a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose <=> an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H(+)


name: hexuronate:monoatomic cation symporter activity


name: Conversion of Glycerol to Glycerol-3-phosphate (Mus musculus)


name: estrone 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => estrone 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate


name: O(6)-methyl-dGTP + H2O => O(6)-methyl-dGMP + diphosphate + H(+)


name: N-terminal L-seryl-[ribosomal protein bL12] + acetyl-CoA => N-terminal N(alpha)-acetyl-L-seryl-[ribosomal protein bL12] + CoA + H(+)


name: cholate + ATP + CoA => choloyl-CoA + AMP + diphosphate


name: ROBO3.1 expression is stimulated by LHX2,(LHX9) (Homo sapiens)


name: a 2,3-di-O-phytanyl-sn-glycerophospholipid + AH2 + 2 S-adenosyl-L-methionine => a macrocyclic archaeaol phospholipid + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol => a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: isoechinulin A + dimethylallyl diphosphate <=> dehydroechinulin + diphosphate


name: p-T,Y MAPK dimers translocate to nucleus (Schizosaccharomyces pombe)


name: AKT phosphorylates FOXO3 downstream of ESR1 and EGFR (Gallus gallus)


name: 6-acetamido-2-oxohexanoate + NAD(+) + H2O => 5-acetamidopentanoate + CO2 + NADH + H(+)


name: phenylglyoxylyl-CoA + H2O => phenylglyoxylate + CoA + H(+)


name: [DsrC protein]-disulfide + hydrogen sulfide + H(+) => [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine


name: RHOQ translocates to the Golgi-associated vesicle membranes (Danio rerio)


name: holo-[compactin nonaketide synthase] + dihydro-ML-236C carboxylate + H(+) => dihydro-ML-236C-[compactin nonaketide synthase] + H2O


name: Proteasomal cleavage of substrate (26S proteasome catalyst) (Homo sapiens)


name: 3,4-dihydroxyphenylethyleneglycol + NAD(+) <=> 3,4-dihydroxymandelaldehyde + NADH + H(+)


name: N-acetyl-alpha-D-glucosamine + NAD(+) + H2O => N-acetyl-D-glucosaminate + NADH + 2 H(+)


name: DHCR7 reduces 7-dehydroCHOL to CHOL (Homo sapiens)


name: theobromine + S-adenosyl-L-methionine = caffeine + S-adenosyl-L-homocysteine + H(+)


name: L-2-aminohexanoate + kynurenate + H2O => 2-oxohexanoate + L-kynurenine


name: 2-succinylbenzoyl-CoA + AMP + diphosphate => 2-succinylbenzoate + ATP + CoA


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Gallus gallus)


name: BRAF autophosphorylates downstream of RAP1 and NGF (Mus musculus)


name: Degradation of ubiquitinated beta catenin by the proteasome (Sus scrofa)


name: Transfer of Ub from E2 to substrate and release of E2 (Sus scrofa)


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Canis familiaris)


name: GAR + 10-Formyl-THF => FGAR + THF (Canis familiaris)


name: TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III (Sus scrofa)


name: Beta defensin 103 activates TLR1:TLR2 (Homo sapiens)


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Xenopus tropicalis)


name: AKAP9:KCNQ1 tetramer:KCNE dimer transports K+ from cytosol to extracellular region (Mus musculus)


name: 5-methylthiopropyl glucosinolate S-oxygenase activity


name: Binding of TFIIIC to TFIIIA:Type I Promoter complex  (Xenopus tropicalis)


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)


name: S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => hexadecanoyl-CoA + H2O


name: a 2,3-diacyl-sn-glycerol + H2O <=> a 3-acyl-sn-glycerol + a fatty acid + H(+)


name: 2-oxo-3-[(8S)-epoxy-(2E,6E)-farnesyl]-6-(pyridin-3-yl)-2H-pyran-4-olate + H(+) => deacetylpyripyropene E


name: TBC1D15 accelerates GTP hydrolysis by RAB7 (Gallus gallus)


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Xenopus tropicalis)


name: L-alanyl-L-valine(in) + H(+)(in) => L-alanyl-L-valine(out) + H(+)(out)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Drosophila melanogaster)


name: an N-(34-hydroxytetratriacontadienoyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol <=> an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontadienoyl)-sphing-4-enine + a diacylglycerol


name: succinate-semialdehyde dehydrogenase (NAD+) activity


name: RAC2 binds effectors at the mitochondrial outer membrane (Drosophila melanogaster)


name: (20S)-19,20-dihydrovomilenine + NADP(+) => vomilenine + NADPH + H(+)


name: triphosphate + guanosine + H(+) => GTP + H2O


name: histone H3K9me2/H3K9me3 demethylase activity


name: N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(out) + n H(+)(out) <=> N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramate(in) + n H(+)(in)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Mus musculus)


name: (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + UDP-alpha-D-glucuronate <=> (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside + UDP


name: c-src associates with Cx43 in gap junctions (Sus scrofa)


name: CSN polymer binds CaPO4 (Rattus norvegicus)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: ARHGAP35 stimulates RHOA GTPase activity (Gallus gallus)


name: methyl acetate + NADP(+) + H2O => acetone + NADPH + O2 + H(+)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Homo sapiens)


name: SLC30A10 transports Mn2+ from cytosol to extracellular region (Schizosaccharomyces pombe)


name: 9-cis-4-hydroxyretinoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 9-cis-4-oxoretinoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: Reduction of disulphide bonds in MHC II antigens (Canis familiaris)


name: Ghrelin O-acyltransferase decanoylates Proghrelin (Gallus gallus)


name: 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z- eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + L-serine <=> 1-(1Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + ethanolamine


name: (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-dichlorophenol + pyruvate + succinate + CO2


name: N(6)-methyl-L-lysyl-[protein] + 2-oxoglutarate + O2 => L-lysyl-[protein] + formaldehyde + succinate + CO2


name: Ubiquitinated Orc1 is degraded by the proteasome (Sus scrofa)


name: (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(out) <=> (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside(in)


name: Pellino binds hp-IRAK1:TRAF6 (Drosophila melanogaster)


name: 2-hydroxy-1,4-benzoquinone + NADH + 2 H(+) <=> benzene-1,2,4-triol + NAD(+)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Homo sapiens)


name: RHOA:GTP binds ROCK, activating it (Drosophila melanogaster)


name: EP300 is recruited to MYC and BCL2 genes (Canis familiaris)


name: catechol + NADPH + H(+) => (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+)


name: 12-(9Z-octadecenoyloxy)-octadecanoate + H2O = 12-hydroxyoctadecanoate + (9Z)-octadecenoate + H(+)


name: Interaction of integrin alphaVbeta3 with von Willbrand Factor (Canis familiaris)


name: Formation of lysyl-pyrrole cross-links (Sus scrofa)


name: Activation of Ca2+ activated Potassium channels with  Intermediate conductance (Dictyostelium discoideum)


name: 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA => 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)


name: (S)-beta-macrocarpene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 => zealexin A1 + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Caenorhabditis elegans)


name: BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 (Homo sapiens)


name: ergothioneyl-alpha-D-lincosamide + GDP + 2 H(+) => GDP-alpha-D-lincosamide + ergothioneine


name: ESR-associated SRC autophosphorylates (Canis familiaris)


name: Membrane estrogen receptors bind SRC (Gallus gallus)


name: NCOA3 binds ESR1:estrogen:TFGA gene (Rattus norvegicus)


name: ApoB-48:TG:PL complex + 100 triacylglycerols + ApoA-I + ApoA-IV => nascent chylomicron (Sus scrofa)


name: SEMA4D interacts with CD72 (Rattus norvegicus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Xenopus tropicalis)


name: (S)-3-methyl-2-oxopentanoate + H(+) <=> 2-methylbutanal + CO2


name: FGF2:TGFBR3 binding to GIPC1 (Mus musculus)


name: Sulfate is exported to the cytosol in exchange for dicarboxylate (Canis familiaris)


name: SLCO2B1-1 transports ASA- from extracellular region to cytosol of GI cells (Canis familiaris)


name: RFC dissociates after sliding clamp formation (Dictyostelium discoideum)


name: 5-amino-2-oxopentanoate + H2O2 + NH4(+) => D-ornithine + O2 + H2O


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Rattus norvegicus)


name: PPP5C dephosphorylates TP53BP1 (Saccharomyces cerevisiae)


name: loading of Serotonin in synaptic vesicles (Homo sapiens)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-6-aminohexanoate + O2 + H2O => (1-deoxy-D-fructos-1-yl)amine + 6-oxohexanoate + H2O2


name: Release of docked serotonin loaded synaptic vesicle (Rattus norvegicus)


name: DCLRE1C (ARTEMIS) processes DNA DSB ends (Mus musculus)


name: a 1,2-saturated fatty acid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a (R)-2-hydroxy fatty acid + 2 Fe(III)-[cytochrome b5] + H2O


name: leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate (Homo sapiens)


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Homo sapiens)


name: kaempferide + S-adenosyl-L-methionine => 3,4'-O-dimethylkaempferol + S-adenosyl-L-homocysteine + H(+)


name: D-glucuronate + ATP <=> 1-phospho-alpha-D-glucuronate + ADP + H(+)


name: Transcriptional activation of CDKN1A by TP53 is inhibited by EP400 (Homo sapiens)


name: phosphatidylinositol phospholipase C activity


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Homo sapiens)


name: PGH2 is reduced to PGF2a by AKR1C3 (Sus scrofa)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose <=> a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + UDP + H(+)


name: IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Xenopus tropicalis)


name: PP2A demethylation by PPME1 (Homo sapiens)


name: a sphingoid base + octadecanoyl-CoA => an N-octadecanoyl-sphingoid base + CoA + H(+)


name: NTRK2-phosphorylated FRS2 binds GRB2 (Xenopus tropicalis)


name: GDP-alpha-D-glucose + alpha-D-mannose 1-phosphate <=> alpha-D-glucose 1-phosphate + GDP-alpha-D-mannose


name: Association of LBP with LPS (Xenopus tropicalis)


name: positive regulation of transforming growth factor beta2 production


name: SRD5A3 reduces pPNOL to DCHOL (Sus scrofa)


name: MYO9B inactivates RHOA (Canis familiaris)


name: 3',3'-cGMP-UMP + 2 diphosphate => UTP + GTP


name: POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Mus musculus)


name: Dephosphorylation of p107 (RBL1) by PP2A (Caenorhabditis elegans)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)


name: NPY gene expression is stimulated by FOXO1 (Homo sapiens)


name: L-lysine + chloride + 2-oxoglutarate + O2 + H(+) = 4-chloro-L-lysine + succinate + CO2 + H2O


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Caenorhabditis elegans)


name: inhibition of 1,2-diacylglycerol kinase (phosphorylating)


name: IRF1 binds the promoters of Interferon alpha and beta (Homo sapiens)


name: Recruitment of HDAC1 by p130 (RBL2) (Sus scrofa)


name: CDKN1A (p21) gene expression is positively regulated by RUNX3 and ZFHX3 (Homo sapiens)


name: myo-inositol + ATP => 1D-myo-inositol 3-phosphate + ADP + H(+)


name: 1-octadecanoyl-sn-glycero-3-phosphate + H2O => 1-octadecanoyl-sn-glycerol + phosphate


name: Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases (Canis familiaris)


name: isolithocholate + NADP(+) => 3-oxo-5beta-cholan-24-oate + NADPH + H(+)


name: Growth Hormone Secretagogue Receptor Interactions


name: ortho-aminobenzoic acid metabolic process


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Danio rerio)


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)


name: 4-hydroxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+) => 4-hydroxy-17beta-estradiol + UDP-alpha-D-glucuronate


name: queuosine(34) in tRNA(Tyr) + guanine => guanosine(34) in tRNA(Tyr) + queuine


name: umbelliferone + dimethylallyl diphosphate = demethylsuberosin + diphosphate


name: imidazole-4-acetate + NADH + 2 H(+) => imidazole-4-acetaldehyde + NAD(+) + H2O


name: 3-amino-5-hydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate => 3-amino-5-hydroxybenzoate + holo-[aryl-carrier protein] + ATP


name: beta-nicotinamide D-ribonucleotide + H2O => nicotinate beta-D-ribonucleotide + NH4(+)


name: resolvin E1 + NAD(+) <=> 18-oxo-resolvin E1 + NADH + H(+)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Bos taurus)


name: (S)-cheilanthifoline + reduced [NADPH--hemoprotein reductase] + O2 = (S)-stylopine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: iE-DAP elicits a NOD1 response (Dictyostelium discoideum)


name: 2-amino-2-deoxy-D-gluconate = (2Z,4S,5R)-2-amino-4,5,6-trihydroxyhex-2-enoate + H2O


name: 1-(3,4,5-trihydroxy-7-methoxynaphthalen-2-yl)propan-2-one + CO2 + NAD(+) => toralactone + NADH + O2 + H(+)


name: RANBP2 SUMOylates HDAC4 with SUMO2,3 (Sus scrofa)


name: an N-acyl-sphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) => an inositol-1-phosphoceramide + a 1,2-diacyl-sn-glycerol


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O => 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)


name: p-S158,221-HuR binds mRNA (Homo sapiens)


name: GRB2:SOS1 complex binds to the active receptor (Gallus gallus)


name: Interleukin-35 translocates from the ER lumen to the extracellular region (Rattus norvegicus)


name: delta(6)-fatty acyl-CoA desaturase activity


name: NEK9 phosphorylates NEK6/NEK7 (Bos taurus)


name: MYSM1 deubiquitinates Histone H2A (Dictyostelium discoideum)


name: 1,2,3-tri-(9Z,12Z,15Z)-octadecatrienoylglycerol + H2O <=> 2,3-di-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycerol + (9Z,12Z,15Z)-octadecatrienoate + H(+)


name: TFAM binds to mitochondrial promoters (Caenorhabditis elegans)


name: USP44 deubiquitinates CDC20 (Sus scrofa)


name: Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Bos taurus)


name: inhibition of protein linear polyubiquitination


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)


name: cAMP hydrolysis by Cam-PDE 1 (Homo sapiens)


name: GSTs transfer GSH to NAPQI to form APAP-SG (Bos taurus)


name: phorbol 12,13-dibutanoate + H2O <=> phorbol 13-butanoate + butanoate + H(+)


name: mandelate + O2 <=> phenylglyoxylate + H2O2


name: cordypyrone A + reduced [NADPH--hemoprotein reductase] + O2 => cordypyrone B + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Translation of NOTCH2NLA mRNA (Homo sapiens)


name: transferase activity, transferring other nitrogenous groups


name: Activation of proMMP7 by MMP3 (Bos taurus)


name: NF-kappa-B complex is transported from cytosol to nucleus (Drosophila melanogaster)


name: Interaction of Tie2 and Grb7 (Homo sapiens)


name: Proteasome mediated degradation of COP1 (Dictyostelium discoideum)


name: L-tryptophan = (E)-3-(indol-3-yl)acrylate + NH4(+)


name: (11Z,14Z,17Z)-eicosatrienoate + O2 => 12-hydroperoxy-(10E,14Z,17Z)-eicosatrienoate


name: an aldehyde + a quinone + H2O => a quinol + a carboxylate + H(+)


name: VAV3 is a GEF for Rho/Rac family kinases (Homo sapiens)


name: KHK dimer phosphorylates Fru to Fru 1-P (Drosophila melanogaster)


name: vanillylamine + (6E)-8-methylnon-6-enoyl-CoA <=> capsaicin + CoA + H(+)


name: HSD17B13 binds lipid droplets (Bos taurus)


name: USP20, USP33 deubiquitinate ADRB2 (Homo sapiens)


name: L-(+)-3-hydroxybutyryl CoA ligase activity


name: LHPP:Mg2+ dimer hydrolyses PPi (Xenopus tropicalis)


name: aminomalonate + (3R)-hydroxyoctadeca-4,10-dienoyl-[ACP] => 3-oxopresphingofungin + holo-[ACP] + CO2


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)


name: Cleavage of hypoxanthine by MPG glycosylase (Gallus gallus)


name: decanal + sulfate + succinate + CO2 + H(+) => decyl sulfate + 2-oxoglutarate + O2


name: SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling (Canis familiaris)


name: RHOD binds effectors at the plasma membrane (Schizosaccharomyces pombe)


name: alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ (Caenorhabditis elegans)


name: eNoSC dimethylates histone H3 at lysine-9 (Saccharomyces cerevisiae)


name: p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Homo sapiens)


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Danio rerio)


name: DERA cleaves dR5P to GA3P and CH3CHO (Caenorhabditis elegans)


name: bassianolide + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+) => 4 (R)-2-hydroxy-3-methylbutyrate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP


name: ALOX12:Fe2+ dehydrogenates 14(S)-Hp-DPAn-3 to 13,14-epoxy-DPAn-3 (Canis familiaris)


name: FABPs bind LCFAs (Drosophila melanogaster)


name: PC is hydrolyzed to 2-acyl LPC by PLA2G4C (Rattus norvegicus)


name: Release of docked serotonin loaded synaptic vesicle (Bos taurus)


name: L-tryptophan = indole + 2-aminoprop-2-enoate


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA => 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA


name: 9-ribosyl-trans-zeatin 5'-phosphate + H2O <=> trans-zeatin + D-ribose 5-phosphate


name: Nuclear VHL:EloB,C:CUL2:RBX1 binds hydroxyprolyl-HIF-alpha (Gallus gallus)


name: positive regulation of ERBB1 signaling pathway involved in cardiac process


name: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + 3'-phosphoadenylyl sulfate = beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + adenosine 3',5'-bisphosphate + H(+)


name: PEX3:PEX19:class I PMP dissociates (Xenopus tropicalis)


name: DPH6 ligates ammonium to diphthine-EEF2 (Canis familiaris)


name: GGCX gamma-carboxylates F2(25-622) (pro-prothrombin) (Rattus norvegicus)


name: Engulfment of particulate antigen into phagocytic vesicle (Mus musculus)


name: [DsrC protein]-dithiol + 2 a quinone + hydrogen sulfide + H(+) <=> [DsrC protein]-trisulfide + 2 a quinol


name: N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+) => N(6),N(6)-dimethyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: 5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine => 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + S-adenosyl-L-homocysteine + H(+)


name: (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => (5Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+)


name: stimulation of protein phosphatase 2 activity


name: (21S)-21-acetoxyl-apo-melianone + reduced [NADPH--hemoprotein reductase] + O2 => (21S)-21-acetyl-1-hydroxy-apo-melianone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-gamma-aminobutanoate => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2


name: HLA-B specific inhibitory MHC class I receptor activity


name: negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 => (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O


name: AXIN is ubiquitinated by SMURF2 (Xenopus tropicalis)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Canis familiaris)


name: gluconate transmembrane transporter activity


name: a short-chain (2E)-enoyl-CoA + H2O => a short-chain (3R)-hydroxy fatty acyl-CoA


name: a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H(+) => a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate


name: 1-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoyl-CoA = 1,3-di-(9Z-octadecenoyl)-glycerol + CoA


name: hexacosanoate + reduced [NADPH--hemoprotein reductase] + O2 => 26-hydroxyhexacosanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PLK1 phosphorylates FIRRM at S43 (Danio rerio)


name: Addition of Nucleotides 5 through 9 on the growing Transcript (Caenorhabditis elegans)


name: LEAP2 binds bacteria (Rattus norvegicus)


name: Formation of the SET1A complex (Homo sapiens)


name: siderophore uptake transmembrane transporter activity


name: dioscin + 3 H2O <=> diosgenin + 2 L-rhamnopyranose + D-glucose


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Rattus norvegicus)


name: acetoacetate(out) + 2 Na(+)(out) = acetoacetate(in) + 2 Na(+)(in)


name: glutathionylspermidine + glutathione + ATP => trypanothione + ADP + phosphate + H(+)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Danio rerio)


name: an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => an N-acylsphing-4-enine 1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol


name: HSPG2 (perlecan) degradation by MMP3, plasmin, (MMP12) (Drosophila melanogaster)


name: PSIP1 binds MEN1 associated with MLL2 complex (Mus musculus)


name: ATP12A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(in) => a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(out)


name: octadecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> (2E)-octadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: O-(ADP-D-ribosyl)-L-seryl-[protein] + H2O <=> ADP-D-ribose + L-seryl-[protein]


name: L-lysyl-[histone] + acetyl-CoA <=> N(6)-acetyl-L-lysyl-[histone] + CoA + H(+)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 3 NADH + 3 O2 + 2 H(+) <=> 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + 3 NAD(+) + 4 H2O


name: p-S407,Y641-STAT6 dimer migrates to the nucleus (Xenopus tropicalis)


name: N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol => N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Collagen type XII degradation by MMP12 (Mus musculus)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Canis familiaris)


name: chlorophyllide a + 2 oxidized [2Fe-2S]-[ferredoxin] => 3,8-divinyl chlorophyllide a + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O = (-)-geosmin + acetone


name: L-glutamyl-L-arginyl-glycyl-L-methionyl-L-threonine(out) + Na(+)(out) => L-glutamyl-L-arginyl-glycyl-L-methionyl-L-threonine(in) + Na(+)(in)


name: Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Bos taurus)


name: Decreased Spinal Cord Disorganized Electrical Activity


name: 2-oxoglutaramate + L-phenylalanine => 3-phenylpyruvate + L-glutamine


name: isopentenyl diphosphate => dimethylallyl diphosphate


name: stimulation of phospholipid biosynthetic process


name: PC is converted to PS by PTDSS1 (Dictyostelium discoideum)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Gallus gallus)


name: 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 => 2 L-citrulline + 2 nitric oxide + NAD(+) + 2 H2O + H(+)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 2 H2O => 3-beta-D-galactosyl-sn-glycerol + 2 a fatty acid + 2 H(+)


name: DMRT1 binds the WNT4 gene (Homo sapiens)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Mus musculus)


name: thiosulfate(out) + 3 Na(+)(out) = thiosulfate(in) + 3 Na(+)(in)


name: an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine => an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol


name: tauroursodeoxycholate(out) + 2 Na(+)(out) => tauroursodeoxycholate(in) + 2 Na(+)(in)


name: PDE5A dimer binds PDE5A inhibitors (Bos taurus)


name: PDE3A inhibitors bind PDE3A (Caenorhabditis elegans)


name: a ganglioside GD1c (d18:1(4E)) + CMP + H(+) => a ganglioside GM1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+)


name: tRNA(Ser) + L-serine + ATP => L-seryl-tRNA(Ser) + AMP + diphosphate + H(+)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)


name: (S)-2-hydroxymethylglutarate + NAD(+) = 2-formylglutarate + NADH + H(+)


name: (2E,6E)-farnesyl diphosphate <=> beta-cadinene + diphosphate


name: Translocation of CDK4/6:CCND complexes from the cytoplasm to the nucleus (Mus musculus)


name: Association of procollagen type XI (Homo sapiens)


name: BTG2 binds CCR4-NOT complex (Sus scrofa)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)


name: Xaa-L-Pro dipeptide + H2O <=> an L-alpha-amino acid + L-proline


name: GSH translocates from cytosol to extracellular region (Homo sapiens)


name: cyclooctat-9-ene-5,7-diol + AH2 + O2 => cyclooctatin + A + H2O


name: Retromer associates with WLS (Homo sapiens)


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Caenorhabditis elegans)


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin (Canis familiaris)


name: NUDT12 hydrolyses NADH to NMNH (Bos taurus)


name: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity


name: ACER1 hydrolyzes ceramide (endoplasmic reticulum) (Homo sapiens)


name: L-aspartate transmembrane transporter activity


name: Activation of Cdc42 (Drosophila melanogaster)


name: Binding of ADAR2 homodimer to dsRNA duplex (Mus musculus)


name: 2xPNPO:2xFMN oxidizes PDXP to PXLP (Caenorhabditis elegans)


name: FAD(in) + ADP(out) => FAD(out) + ADP(in)


name: Caspase-mediated cleavage of MASK (Mus musculus)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Drosophila melanogaster)


name: 1'-[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-3'-[1-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoate + H(+) => 1',3'-bis[1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + H2O


name: Dissociation of the P2Y purinoceptor 12:Gi complex (Homo sapiens)


name: neomycin C + AH2 + S-adenosyl-L-methionine <=> neomycin B + 5'-deoxyadenosine + L-methionine + A + H(+)


name: Trans-homodimerization of Neurofascin (Rattus norvegicus)


name: delphinidin + UDP-alpha-D-glucose => delphinidin 3-O-beta-D-glucoside + UDP


name: DOLK phosphorylates DCHOL to DOLP (Xenopus tropicalis)


name: SFTPB gene produces pro-SFTPB protein (Homo sapiens)


name: CO binds to Cytochrome c oxidase (Sus scrofa)


name: Inactivation of MAP2K1 by CDK1 (Caenorhabditis elegans)


name: (3R)-3-hydroxypentanoate + CoA + H(+) => (3R)-3-hydroxypentanoyl-CoA + H2O


name: CRY:PER heterodimer binds the BMAL1:CLOCK/NPAS2 heterodimer (Homo sapiens)


name: ALPK1:ADP-heptose:TIFA oligomer recruits TRAF6 (Homo sapiens)


name: (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA + H2O <=> 6-methyl-3,7-dioxodecanedioyl-CoA


name: succinate(out) + phosphate(in) = succinate(in) + phosphate(out)


name: 3,4-dimethoxy-L-phenylalanine = 3,4-dimethoxy-(E)-cinnamate + NH4(+)


name: I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Mus musculus)


name: Transport of antigen loaded MHC II molecules to surface (Homo sapiens)


name: N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-5,10-methenyltetrahydrofolate + H2O <=> N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + 2 H(+)


name: gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling


name: Increased Sympathetic Brain Derived Neurotropic Activity


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Homo sapiens)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Drosophila melanogaster)


name: positive regulation of terrequinone A biosynthetic process


name: Inactive RAFs bind YWHAB (Drosophila melanogaster)


name: SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Canis familiaris)


name: L-phenylalanine(out) + chloride(out) + 2 Na(+)(out) = L-phenylalanine(in) + chloride(in) + 2 Na(+)(in)


name: Disassembly of tight junctions (Drosophila melanogaster)


name: ALOX5 dehydrogenates 7(S)-Hp-17R-HDHA to 7S(8)-epoxy-17R-HDHA (Danio rerio)


name: pratensein + reduced [NADPH--hemoprotein reductase] + O2 = 5-hydroxypseudobaptigenin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: GNRHR binds GNRHR peptide antagonists (Rattus norvegicus)


name: Trimerization of the FASL:FAS receptor complex (Homo sapiens)


name: Fe(III)-[cytochrome c](in) => Fe(III)-[cytochrome c](out)


name: mycinamicin VI + S-adenosyl-L-methionine => mycinamicin III + S-adenosyl-L-homocysteine + H(+)


name: nitric-oxide synthase inhibitor activity


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Caenorhabditis elegans)


name: ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Drosophila melanogaster)


name: 8-demethyl-8-formylriboflavin 5'-phosphate + H2O => FMN + O2


name: 13-hydroxy-alpha-tocopherol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (+)-alpha-tocopherol + reduced [NADPH--hemoprotein reductase] + O2


name: 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + 2 S-adenosyl-L-homocysteine + 2 H(+) => C30 botryococcene + 2 S-adenosyl-L-methionine


name: acyl-lipid omega-6 desaturase (cytochrome b5)


name: Autoglucosylation of GYG1 complexed with GYS1-b (Caenorhabditis elegans)


name: deoxycholate + FAD + H2O + H(+) => cholate + FADH2


name: ABCG4 may mediate cholesterol efflux (Drosophila melanogaster)


name: Interaction of particulate antigens with dendritic cell receptors (Mus musculus)


name: lipoprotein biosynthetic process via signal peptide cleavage


name: (2E,6E,10E)-geranylgeranate + 2 NADP(+) + 3 H2O => (2E,6E,10E)-geranylgeraniol + 2 NADPH + 2 O2 + H(+)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Sus scrofa)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol => a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a triacylglycerol


name: an N-acylsphingoid base 1-phosphate(in) <=> an N-acylsphingoid base 1-phosphate(out)


name: rhamnacene + S-adenosyl-L-homocysteine + H(+) => rhamnetin + S-adenosyl-L-methionine


name: 3,4-dihydroxybenzoate + UDP-alpha-D-glucose = 1-O-(3,4-dihydroxy-benzoyl)-beta-D-glucose + UDP


name: Release of activated MAD2 from kinetochores (Bos taurus)


name: positive regulation of hexokinase activity


name: protein-arginine omega-N monomethyltransferase activity


name: Loading and methylation of Sm proteins onto SMN Complexes (Rattus norvegicus)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Rattus norvegicus)


name: GNB2L1 binds IKKA:IKKB:NEMO (Drosophila melanogaster)


name: KDSR reduces 3-ketosphingoid (Xenopus tropicalis)


name: N(6)-acetyl-L-lysyl-[alpha-tubulin] + CoA + H(+) => L-lysyl-[alpha-tubulin] + acetyl-CoA


name: The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Danio rerio)


name: TP53 binds the RABGGTA gene (Homo sapiens)


name: Formation of the lid particle 2 (LP2) (Homo sapiens)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Xenopus tropicalis)


name: Synthesis of dolichyl-phosphate-glucose (Canis familiaris)


name: (R)-malate + a quinone <=> enol-oxaloacetate + a quinol


name: CAST binds Ca2+ bound calpain (Homo sapiens)


name: The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Canis familiaris)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Plasmodium falciparum)


name: methyl beta-D-galactoside(out) + ATP + H2O => methyl beta-D-galactoside(in) + ADP + phosphate + H(+)


name: L1 binds to AP-2 Clathrin complex (Xenopus tropicalis)


name: N(6)-methyl-L-lysyl-[protein] + A + H2O <=> L-lysyl-[protein] + formaldehyde + AH2


name: NPC transports Hikeshi:HSP70s:ATP from cytosol to nucleoplasm (Homo sapiens)


name: The addition of GalNAc to the terminal glucuronate residue forms chondroitin (Sus scrofa)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Gallus gallus)


name: Deubiquitinated PTEN translocates to the cytosol (Dictyostelium discoideum)


name: Ghrelin O-acyltransferase decanoylates Proghrelin (Danio rerio)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Mus musculus)


name: Addition of galactose to Core 6 glycoprotein (Mus musculus)


name: SLC25A18,22 import L-Glu, H+ (Dictyostelium discoideum)


name: uridine(20) in tRNA + NADH + H(+) => 5,6-dihydrouridine(20) in tRNA + NAD(+)


name: N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 2-oxoglutarate + O2 => N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + formaldehyde + succinate + CO2


name: holo-[ACP] + acetyl-CoA => acetyl-[ACP] + CoA


name: JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Mus musculus)


name: a quinone + NADPH + H(+) = a quinol + NADP(+)


name: AKR1B1 reduces Glc to D-sorbitol (Bos taurus)


name: a beta-D-galactoside + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H(+)


name: Displacement of MPG glycosylase by APEX1 at the AP site (Sus scrofa)


name: L-leucine(out) + L-arginine(in) = L-leucine(in) + L-arginine(out)


name: methylmalonate + NADH + 2 H(+) => (S)-2-methyl-3-oxopropanoate + NAD(+) + H2O


name: a uridine in 12S rRNA + S-adenosyl-L-methionine => a 5-methyluridine in 12S rRNA + S-adenosyl-L-homocysteine + H(+)


name: 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate + a 1,2-diacyl-sn-glycerol => an alpha-D-GlcN-(1->6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol


name: tyrosine phosphorylation of Stat6 protein


name: PIAS2,3,4 SUMOylate RORA with SUMO2 (Sus scrofa)


name: tetradecanedioate + ATP + CoA <=> tetradecanedioyl-CoA + AMP + diphosphate


name: Gq-BTK complex dissociates to Active BTK and Gq (Sus scrofa)


name: (20S)-ginsenoside Re + H2O => (20S)-ginsenoside Rg1 + L-rhamnopyranose


name: AFG3L2:SPG7 binds SMDT1 (EMRE) (Canis familiaris)


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Saccharomyces cerevisiae)


name: (R)-noradrenaline(out) + chloride(out) + Na(+)(out) = (R)-noradrenaline(in) + chloride(in) + Na(+)(in)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O => 1,2-dihexadecanoyl-sn-glycerol + phosphoethanolamine + H(+)


name: [(1->4)-3,6-bisphospho-alpha-D-glucosyl](n) + n AMP + n phosphate + 2n H(+) => [(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O


name: a ganglioside GT1a (d18:1(4E)) + H2O <=> a ganglioside GD1a (d18:1(4E)) + N-acetylneuraminate


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Bos taurus)


name: CREBBP, EP300 acetylates NFE2L2 (Rattus norvegicus)


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + L-glutamate => [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate + 2-oxoglutarate


name: O-phospho-L-homoserine + ADP + H(+) => L-homoserine + ATP


name: a globoside Gb3Cer (d18:1(4E)) + UDP-alpha-D-galactose <=> a globoside GalGb3Cer (d18:1(4E)) + UDP + H(+)


name: Translocation of YAP1:ZO-2 (TJP2) to the nucleus (Bos taurus)


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Bos taurus)


name: beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP-alpha-D-galactofuranose = beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP + H(+)


name: PDSS1,2 ligates FPP to IPPP (Mus musculus)


name: 4-hydroxy-L-threonine + phosphate => 4-(phosphooxy)-L-threonine + H2O


name: Nef Binds and activates the Src-family tyrosine kinase Fyn (Homo sapiens)


name: a methoxylated aromatic compound + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) => a phenol + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein]


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Danio rerio)


name: tigecycline + NADPH + O2 + H(+) => 11a-hydroxytigecycline + NADP(+) + H2O


name: GSDMD (1-275) binds bacterial cardiolipin (Mus musculus)


name: ALPK1 binds ADP-heptose (Xenopus tropicalis)


name: baccharis oxide => (S)-2,3-epoxysqualene


name: AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA (Xenopus tropicalis)


name: sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA <=> (9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: (2E)-tetradecenoyl-CoA + H2O2 => tetradecanoyl-CoA + O2


name: Src kinases phosphorylate VAV (Bos taurus)


name: (2S,4R)-bornyl diphosphate => (2E)-geranyl diphosphate


name: TNFRSF6B binds TNFSF6,14,15 (Bos taurus)


name: Phosphorylation of PDPK1 on serine-241 (Dictyostelium discoideum)


name: MRN complex binds shortened telomeres (Rattus norvegicus)


name: NCOA3 binds ESR1:estrogen:TFGA gene (Sus scrofa)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Caenorhabditis elegans)


name: PLB1 hydrolyses RPALM to atROL (Bos taurus)


name: N-acetylisatin + H2O => N-acetylindoxyl + O2


name: ABL1 phosphorylates PPARG2 (Gallus gallus)


name: SGPP1,2 dephosphorylate sphingoid-1-phosphates (Schizosaccharomyces pombe)


name: DCC interaction with SIAH1 (Drosophila melanogaster)


name: Factor B binds to surface-associated C3b (Mus musculus)


name: GNAT1-GTP hydrolyses its bound GTP to GDP (Homo sapiens)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + N-acetylneuraminate => a ganglioside GM3 + H2O


name: inhibition of [4Fe-4S] cluster biosynthetic process


name: MTORC1 dissociates from ULK complex (Gallus gallus)


name: Neogenin:Netrin-3 binds CDO complex (Homo sapiens)


name: SARS-CoV-2 N binds to G3BP1,G3BP2 (Homo sapiens)


name: Formation of Processive Complex (Rattus norvegicus)


name: IL3 stimulation induces Vav binding to Tec kinase (Homo sapiens)


name: Gamma-secretase cleaves CNTN1:NOTCH2 to release NICD2 (Homo sapiens)


name: 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + NAD(+) <=> cycloeucalenone + CO2 + NADH


name: (2E)-decenoyl-CoA + H2O => (3S)-hydroxydecanoyl-CoA


name: cumene hydroperoxide + 2 glutathione <=> 2-phenylpropan-2-ol + glutathione disulfide + H2O


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Homo sapiens)


name: Formation of the IGF:IGFBP5:ALS complex (Danio rerio)


name: 1D-myo-inositol 1,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,4,5-trisphosphate + phosphate


name: positive regulation of interleukin-35 production


name: Release of novel PDGFs as latent factors (Mus musculus)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Drosophila melanogaster)


name: a primary alcohol + NAD(+) = an aldehyde + NADH + H(+)


name: L-seryl-tRNA(Sec) + selenophosphate + H(+) <=> L-selenocysteinyl-tRNA(Sec) + phosphate


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Drosophila melanogaster)


name: Association of LBP with bacterial LPS (Gallus gallus)


name: 18-hydroxy-9alpha,11alpha-methylene thromboxane A2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 9alpha,11alpha-methylene thromboxane A2 + reduced [NADPH--hemoprotein reductase] + O2


name: SLC34A3 cotransports Pi, 2Na+ (Sus scrofa)


name: soyasaponin III rhamnosyltransferase activity


name: (S)-lactate + O2 <=> acetate + CO2 + H2O


name: agmatine + O2 + H2O <=> N-amidino-(2R)-hydroxypyrrolidine + H2O2 + NH4(+)


name: RDH10,16,DHRS9,RDHE2 oxidise atROL to atRAL (Bos taurus)


name: N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(out) + n H(+)(out) <=> N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate(in) + n H(+)(in)


name: FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc (Caenorhabditis elegans)


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Bos taurus)


name: N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) + 2 H(+)(out) = N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) + 2 H(+)(in)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Drosophila melanogaster)


name: SARS-CoV-1 E transports Ca2+  (Homo sapiens)


name: a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = a 3-demethylubiquinol + A + H2O


name: (2Z,6E)-farnesyl diphosphate + 10 isopentenyl diphosphate => di-trans,deca-cis-tridecaprenyl diphosphate + 10 diphosphate


name: 4-methylcholesta-8(9),24-dien-3-one is reduced to 4-methylcholesta-8(9),24-dien-3beta-ol (Mus musculus)


name: ACLY tetramer binds ETC-1002-CoA (Danio rerio)


name: activation of glycoprotein-specific chaperone activity


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)


name: Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Canis familiaris)


name: GSR catalyzes glutathione (oxidized) + NADPH + H+ => 2 glutathione (reduced) + NADP+ (Plasmodium falciparum)


name: nuclear glucocorticoid receptor activity


name: (2S)-naringenin + S-adenosyl-L-methionine => (2S)-sakuranetin + S-adenosyl-L-homocysteine + H(+)


name: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) => 2-aminomuconate 6-semialdehyde + CO2


name: NPM1-ALK fusion dimer binds SKP1:CUL1:RBX1:ZC3HC1 (Homo sapiens)


name: O-(5'-guanylyl)-L-tyrosyl-[protein] + diphosphate => L-tyrosyl-[protein] + GTP


name: glyoxalase (glycolic acid-forming) activity


name: D-cellobiose + H2O = beta-D-glucose + D-glucose


name: p-T816-PKN2 phosphorylates AKT1 on serine-308 (Caenorhabditis elegans)


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Xenopus tropicalis)


name: P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O <=> AMP + ADP + 2 H(+)


name: 2-methyl-trans-aconitate + H2O => (2S,3S)-2-methylcitrate


name: alpha-L-fucosyl-(1->2)- beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + GDP + H(+) => a beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer(d18:1(4E)) + GDP-beta-L-fucose


name: activation of cutin biosynthetic process


name: a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O <=> a neolactoside nLc4Cer(d18:1(4E)) + L-fucose


name: LIG1 bound to POLB ligates SSB (Canis familiaris)


name: The Ligand:GPCR:Gi complex dissociates (Mus musculus)


name: CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation (Caenorhabditis elegans)


name: typhasterol + reduced [NADPH--hemoprotein reductase] + O2 = 7-oxatyphasterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (+)-epi-isozizaene + diphosphate => (2E,6E)-farnesyl diphosphate


name: "phosphogluconate dehydrogenase [NAD(P)(+)-dependent, decarboxylating]"


name: (4Z,15Z)-bilirubin IXalpha + NADP(+) = biliverdin IXalpha + NADPH + H(+)


name: SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: triacetin + H2O = diacetylglycerol + acetate + H(+)


name: formate dehydrogenase (quinone) activity


name: SLCO1B1,1B3,2B1-3 transport ATV from extracelluar region to cytosol (Mus musculus)


name: CoA-disulfide reductase (NADPH) activity


name: 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + 2 phosphate + 2 H(+) => GTP + 3 H2O


name: p-Y483 BACH1 translocates from the nucleoplasm to the cytosol (Gallus gallus)


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Rattus norvegicus)


name: Netrin-1 induced DCC clustering (Xenopus tropicalis)


name: DSPG and CSPG translocate to the lysosome for degradation (Drosophila melanogaster)


name: Formation of AT-AC C complex (Drosophila melanogaster)


name: Recognition and binding of the mRNA cap by the cap-binding complex  (Xenopus tropicalis)


name: 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Homo sapiens)


name: KCNK dimers transport K+ from cytosol to extracellular region (Canis familiaris)


name: Docking of Mature Histone mRNA complex:TAP at the NPC (Schizosaccharomyces pombe)


name: Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Homo sapiens)


name: 11beta-hydroxyandrost-4-ene-3,17-dione + NAD(+) <=> androst-4-ene-3,11,17-trione + NADH + H(+)


name: PCK1 phosphorylates OA to yield PEP (Canis familiaris)


name: VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Homo sapiens)


name: Kinesin-1 is a heterotetramer (Caenorhabditis elegans)


name: BTNL8 binds resting T cell surface (Xenopus tropicalis)


name: 8-methylmenaquinone-6 + succinate <=> 8-methylmenaquinol-6 + fumarate


name: CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Dictyostelium discoideum)


name: acireductone dioxygenase [iron(II)-requiring] activity


name: 2-dehydro-D-glucose + L-glutamate => (2S)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]pentanedioate + H2O + H(+)


name: Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 (Homo sapiens)


name: IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Mus musculus)


name: RHOD binds effectors at the Golgi membrane (Mus musculus)


name: apo-[alkylcobalamin reductase] + adenosylcob(III)alamin + glutathione <=> S-adenosylglutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+)


name: Noradrenaline clearance from the synaptic cleft (Drosophila melanogaster)


name: Formation of the MCC complex (Schizosaccharomyces pombe)


name: IDUA hydrolyses Heparan sulfate chain(1) (Homo sapiens)


name: a beta-D-glucosylceramide + UDP-alpha-D-galactose <=> a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP + H(+)


name: an alkylmercury + H(+) => an alkane + Hg(2+)


name: a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate => alpha,alpha-trehalose 6-phosphate + a ribonucleoside 5'-diphosphate + H(+)


name: p-S193-KSRP binds 14-3-3zeta in the nucleus (Bos taurus)


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Mus musculus)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Gallus gallus)


name: L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine + H(+)


name: triphosphate + ADP + H(+) => diphosphate + ATP


name: 4-hydroxybenzyl alcohol + 2 oxidized [azurin] <=> 2 reduced [azurin] + 4-hydroxybenzaldehyde + 2 H(+)


name: 3,5-diiodo-L-tyrosine + NADPH + H(+) => 3-iodo-L-tyrosine + iodide + NADP(+)


name: 2 (3,4-dimethoxyphenyl)methanol + H2O2 = 2 (3,4-dimethoxyphenyl)methanol radical + 2 H2O


name: Direct recruitment of PI3K to p-KIT (Xenopus tropicalis)


name: Expression of Phosphoenolpyruvate carboxykinase 1 (PEPCK-C) (Homo sapiens)


name: MRSBs reduce L-methyl-(R)-S-oxide to L-methionine (Rattus norvegicus)


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Sus scrofa)


name: RTC completes synthesis of the minus strand genomic RNA complement (Homo sapiens)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP (Danio rerio)


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Rattus norvegicus)


name: 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + L-glutamate => 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + 2-oxoglutarate


name: 2 L-leucyl-tRNA(Leu) => cyclo(L-leucyl-L-leucyl) + 2 tRNA(Leu) + 2 H(+)


name: RHOF GAPs stimulate RHOF GTPase activity (Sus scrofa)


name: (2E)-hexadecenoyl-[ACP] + NADPH + H(+) => hexadecanoyl-[ACP] + NADP(+)


name: Disassociation of Telomerase RNP and the Chromosome End (Bos taurus)


name: Tenascins C, R, (X, N) bind lecticans (Canis familiaris)


name: CYB5A:heme reduces Asc.- to AscH- (Rattus norvegicus)


name: 17beta-hydroxy-5alpha-androstan-3-one + NAD(+) = 5alpha-androstan-3,17-dione + NADH + H(+)


name: RP2 binds ARL3:GTP:UNC119B (Rattus norvegicus)


name: IL12A:IL12B translocates from late endosome lumen to extracellular region (Mus musculus)


name: 1,2-dihexadecanoyl-sn-glycero-3-CDP + myo-inositol = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)


name: Movement of clathrin coated vesicles into early endosome (Xenopus tropicalis)


name: 2-nitrobutanedioate => fumarate + nitrite + H(+)


name: PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Rattus norvegicus)


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Xenopus tropicalis)


name: Cleavage of Procaspase-7 by the apoptosome (Danio rerio)


name: Expression of LFNG in presomitic mesoderm (Homo sapiens)


name: A3 adenosine receptor activity, G protein coupled


name: adlupulone + diphosphate + H(+) => deoxyadlupulone + dimethylallyl diphosphate


name: PI4P is dephosphorylated to PI by SACM1L at the Golgi membrane (Saccharomyces cerevisiae)


name: Long-range resection of DNA DSBs by EXO1 or DNA2 (Mus musculus)


name: (3R)-3-hydroxydecanoyl-CoA + NAD(+) <=> 3-oxodecanoyl-CoA + NADH + H(+)


name: H3/H4 histone acetyltransferase activity


name: S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] + H2O => S-disulfanyl-L-cysteinyl-[SoxY protein] + sulfate + H(+)


name: Defective GALNT12 does not transfer GalNAc to mucins (Homo sapiens)


name: 2-amino-5-chlorophenol + O2 = 2-amino-5-chloromuconate 6-semialdehyde


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide


name: Association of Acrosin Heavy and Light Chain (Rattus norvegicus)


name: phenylalanine + pyruvate => 3-(indol-3-yl)pyruvate + alanine (Sus scrofa)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Rattus norvegicus)


name: Budding of connexon-containing transport vesicles from the Golgi (Rattus norvegicus)


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Xenopus tropicalis)


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Bos taurus)


name: 2-hydroxybenzoyl-5'-AMP + CoA <=> 2-hydroxybenzoyl-CoA + AMP + H(+)


name: Insertion of MHC II:Ii complex in to the plasma membrane (Canis familiaris)


name: Vitronectin (VTN) binds to C5b:C6:C7 (Sus scrofa)


name: N-terminal L-threonyl-[protein] + acetyl-CoA <=> N-terminal N(alpha)-acetyl-L-threonyl-[protein] + CoA + H(+)


name: D-ribono-1,4-lactone + NADH + H(+) = D-ribose + NAD(+)


name: 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O <=> 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + 2 H(+)


name: dCMP + H2O = 2'-deoxycytidine + phosphate


name: dodecanamide + glyoxylate => N-dodecanoyl-(2S)-hydroxyglycine


name: NSF and SNAPs bind cis-SNARE complex (Plasmodium falciparum)


name: alpha-ribazole 5'-phosphate + adenosylcob(III)inamide-GDP => adenosylcob(III)alamin 5'-phosphate + GMP + H(+)


name: 3-(2-methylsulfanyl)ethylmalate = 2-(2-methylsulfanyl)ethylmaleate + H2O


name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate (Homo sapiens)


name: Proteasome degrades polyubiquitinated PTEN (Saccharomyces cerevisiae)


name: Connexin 45/Connexin 36 mediated neuronal gap junction communication (Sus scrofa)


name: 2,5-dihydroxybenzoate + H(+) => hydroquinone + CO2


name: hydrogencarbonate(out) + Na(+)(out) => hydrogencarbonate(in) + Na(+)(in)


name: LMCD1 binds GATA6, sequestering it (Xenopus tropicalis)


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Bos taurus)


name: Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Canis familiaris)


name: a globoside Gb4Cer (d18:1(4E)) + UDP-alpha-D-galactose <=> a globoside GalGb4Cer (d18:1(4E)) + UDP + H(+)


name: (R)-lactate + chloride + H(+) => (S)-2-chloropropanoate + H2O


name: Expression of SERPINE1 (PAI-1) (Homo sapiens)


name: YWHAB dimer dissociates from dephosphorylated RAF (Gallus gallus)


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Gallus gallus)


name: DVL recruits GSK3beta:AXIN1 to the receptor complex (Homo sapiens)


name: testosterone + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 1alpha-hydroxytestosterone + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: ATF5 and HSF1 trimer bind the bidirectional promoter of the HSPD1 gene and HSPE1 gene (Homo sapiens)


name: cholesterol(out) + ADP + phosphate + H(+) => cholesterol(in) + ATP + H2O


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Schizosaccharomyces pombe)


name: Association of DFF with alpha:beta importin (Homo sapiens)


name: 3-methylbutanal + NADP(+) + H2O = 3-methylbutanoate + NADPH + 2 H(+)


name: but-3-ynal + NAD(+) + H2O <=> 3-butynoate + NADH + 2 H(+)


name: theobromine + NADPH + O2 + H(+) <=> 7-methylxanthine + formaldehyde + NADP(+) + H2O


name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] (Xenopus tropicalis)


name: RANBP2 SUMOylates MDM2 with SUMO1 (Mus musculus)


name: E2F6:TFDP1 binds EPC1 (Canis familiaris)


name: all-trans-4,4'-diapophytofluene + FAD + H(+) => all-trans-4,4'-diapo-zeta-carotene + FADH2


name: a 1-O-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O


name: Active ALK phosphorylates PLCG1 (Mus musculus)


name: (2Z,6Z)-farnesyl diphosphate => gamma-curcumene + diphosphate


name: 2 glutathione + O2 => glutathione disulfide + H2O2


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Dictyostelium discoideum)


name: a flavonol 3-O-glycoside + UDP-alpha-D-xylose => a flavonol 3-O-[beta-D-xylosyl-(1->2)-beta-D-glycoside] + UDP + H(+)


name: alpha-D-ribose 1,5-bisphosphate + AMP + H(+) => alpha-D-ribose 1-phosphate + ADP


name: TOPORS SUMOylates IKBKE with SUMO1 (Bos taurus)


name: Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + S-adenosyl-L-homocysteine + CO2


name: HA:HAR:HYAL2 binds to SLC9A1:p-CHP:Ca2+ (Mus musculus)


name: tenuazonic acid + AMP + diphosphate + CoA + 2 H(+) => acetoacetyl-CoA + L-isoleucine + ATP


name: (9Z)-octadecenoate + glycine = N-(9Z-octadecenoyl)glycine + H2O


name: L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)


name: SUMOylation of DDX5 with SUMO1 (Xenopus tropicalis)


name: a phenol + 3'-phosphoadenylyl sulfate <=> an aryl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: [DsbD protein]-disulfide + [protein]-dithiol => [DsbB protein]-dithiol + [protein]-disulfide


name: N-(9Z-octadecenoyl)-L-serine + H2O = L-serine + (9Z)-octadecenoate


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Mus musculus)


name: a D-hexose + an acyl phosphate = a D-hexose phosphate + a carboxylate + H(+)


name: SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)


name: protoviolaceinate + NADPH + 2 O2 + 2 H(+) <=> violacein + CO2 + NADP(+) + 2 H2O


name: PI(3,5)P2 is dephosphorylated to PI3P by SYNJ at the plasma membrane (Bos taurus)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Mus musculus)


name: testosterone + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 => 17beta-estradiol + formate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: 1,3-dinitrobenzene + NADH + O2 = 4-nitrocatechol + nitrite + NAD(+) + H(+)


name: RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL (Danio rerio)


name: L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)


name: Interaction of DAP12 and KIR2DS1 (Rattus norvegicus)


name: Hydrolysis of PIP3 to PI(3,4)P2 (Rattus norvegicus)


name: Recruitment Of Cytoplasmic Proteins To Vesicles (Mus musculus)


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Canis familiaris)


name: 3 oxidized coenzyme F420-(gamma-L-Glu)(n) + hydrogen sulfide + 3 H2O + 2 H(+) <=> 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Plasmodium falciparum)


name: negative regulation of retinoic acid receptor signaling pathway


name: cAMP activates EPAC1 (Xenopus tropicalis)


name: p-nitrophenol + PAPS => p-nitrophenol sulfate + PAP (Canis familiaris)


name: ARTN binds RET:GFRA1,GFRA3 (Gallus gallus)


name: regulation of ATPase-coupled calcium transmembrane transporter activity


name: dATP + CO2 + H2O => formate + ATP + H(+)


name: cortisol + 3'-phosphoadenylyl sulfate = cortisol 21-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Drosophila melanogaster)


name: 13-cis-retinyl ester + CoA => 13-cis-retinol + a fatty acyl-CoA


name: glycyl-L-glutamate(out) + ATP + H2O <=> glycyl-L-glutamate(in) + ADP + phosphate + H(+)


name: CMBL hydrolyses OM to OLMS (Mus musculus)


name: Cleavage of Procaspase-3 by the apoptosome (Sus scrofa)


name: (R)-lactate + NADP(+) => pyruvate + NADPH + H(+)


name: hexadecanoyl-CoA + acetyl-CoA = 3-oxooctadecanoyl-CoA + CoA


name: (E)-caffeoyl-CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 NADH => hydrocaffeoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+)


name: inositol pentakisphosphate 2-kinase activity


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Caenorhabditis elegans)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Drosophila melanogaster)


name: a medium-chain (3R)-hydroxyacyl-CoA => a medium-chain (2E)-enoyl-CoA + H2O


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Homo sapiens)


name: D-mannonate + NADP(+) => D-mannuronate + NADPH + H(+)


name: Formation of classic pathway C5 convertase (Gallus gallus)


name: UGTs glucuronate APAP to APAP-GlcA (Caenorhabditis elegans)


name: PAK1 phosphorylates myosin phosphatase (Rattus norvegicus)


name: SGMS2 transfers phosphocholine onto ceramide (Plasmodium falciparum)


name: 3-phenylpyruvate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-phenylalanine


name: UGT1A3 lactonizes ATV to ATVL (Sus scrofa)


name: negative regulation of tetrapyrrole catabolic process


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Rattus norvegicus)


name: Defective UGT1A4 does not transfer GlcA from UDP-GlcA to BIL (Homo sapiens)


name: ilicicolin A + NADPH + O2 + H(+) => ilicicolin A epoxide + NADP(+) + H2O


name: CYP4F12 18-hydroxylates ARA (Mus musculus)


name: PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Sus scrofa)


name: penilactone D + o-quinone methide + H(+) <=> penilactone B


name: an N-acylethanolamine phosphate + H2O = an N-acylethanolamine + phosphate


name: (R)-epichlorohydrin + H2O => (R)-3-chloro-1,2-propanediol


name: SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Homo sapiens)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Dictyostelium discoideum)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Drosophila melanogaster)


name: Depolymerization of lamin filaments after PKC-mediated phosphorylation (Sus scrofa)


name: multicellular organismal protein metabolic process


name: Na+/H+ exchanger transport (at cell membrane) (Danio rerio)


name: PAK1-3 phosphorylates VE-cadherin (Sus scrofa)


name: chrodrimanin T + NADPH + O2 + H(+) <=> chrodrimanin A + NADP(+) + H2O


name: L-lysine(out) + L-arginine(in) <=> L-lysine(in) + L-arginine(out)


name: L-asparagine + H2O = L-aspartate + NH4(+)


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol <=> 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+)


name: N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein] + H2O <=> N-terminal L-aspartyl-[protein] + N(alpha)-acetyl-L-methionine


name: (2E,6E)-farnesyl diphosphate + H2O => (+)-(1(10)E,4E,6S,7R)-germacradien-6-ol + diphosphate


name: MRS2 transports Mg2+ from cytosol to mitochondrial matrix (Homo sapiens)


name: 1,2,3-tri-(9Z,12Z,15Z)-octadecatrienoylglycerol + H2O => 2,3-di-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycerol + (9Z,12Z,15Z)-octadecatrienoate + H(+)


name: activation of arugosin biosynthetic process


name: adenosine(9) in tRNA + S-adenosyl-L-methionine => N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: Sos-mediated nucleotide exchange of Ras (Tie2 receptor:Grb2:Sos) (Bos taurus)


name: 5,10-dihydrophenazine 1-carboxylate + O2 = phenazine-1-carboxylate + H2O2


name: Beta defensin 103 activates TLR1:TLR2 (Gallus gallus)


name: 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+) => 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-ethanolamine


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Sus scrofa)


name: Homocysteine is degraded to oxobutanoate and H2S (Xenopus tropicalis)


name: STAT4 binds IL12RB2:IL12RB2 (Canis familiaris)


name: a peptide antigen(in) + ATP + H2O <=> a peptide antigen(out) + ADP + phosphate + H(+)


name: G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Bos taurus)


name: CDK1 phosphorylates MAPK6 (Rattus norvegicus)


name: L-tyrosine(out) + chloride(out) + 2 Na(+)(out) <=> L-tyrosine(in) + chloride(in) + 2 Na(+)(in)


name: erythromycin B + S-adenosyl-L-homocysteine + H(+) => erythromycin D + S-adenosyl-L-methionine


name: (2E,13Z)-docosadienoyl-CoA + NADPH + H(+) <=> (13Z)-docosenoyl-CoA + NADP(+)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Drosophila melanogaster)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Rattus norvegicus)


name: HMG CoA => acetoacetic acid + acetyl CoA (Rattus norvegicus)


name: Binding of cAMP to HCN channels (Gallus gallus)


name: 7-carboxymellein + L-phenylalanine + ATP = ochratoxin B + ADP + phosphate + H(+)


name: hexanoyl-CoA + 3 malonyl-CoA + 3 H(+) <=> 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: a D-hexose + ATP <=> a D-hexose 6-phosphate + ADP + H(+)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Homo sapiens)


name: XDH oxidises 6MP to 6TU (Xenopus tropicalis)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine => sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)


name: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+)


name: alpha,alpha-trehalose + H2O => alpha-D-glucose + beta-D-glucose


name: ALOX5 oxidises 13(R)-HDPAn-3 to RvT1-4 (Canis familiaris)


name: calcitriol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => calcidiol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: glycine betaine(in) = glycine betaine(out)


name: molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)


name: F1Fo ATP synthase dimerizes (Sus scrofa)


name: IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)


name: chrodrimanin T + NADPH + O2 + H(+) = chrodrimanin A + NADP(+) + H2O


name: beta-D-glucosyl-(1<->1)-sphing-4-enine + a fatty acid => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + H2O


name: 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin] + NAD(+) = 2 reduced [2Fe-2S]-[ferredoxin] + 2 CO2 + NADH + H(+)


name: "formate dehydrogenase (NAD(+), ferredoxin)"


name: estrone + 3'-phosphoadenylyl sulfate = estrone 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 25-hydroxy-24-oxocalciol + 2 reduced [adrenodoxin] + O2 + 2 H(+) <=> 23S,25-dihydroxy-24-oxocholecalciferol + 2 oxidized [adrenodoxin] + H2O


name: 2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O


name: L-lysyl-[protein] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)


name: Aquaporin-7 passively transports glycerol out of cell (Bos taurus)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+) => 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADH + H(+)


name: L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-methionine => N(6),N(6),N(6)-trimethyl-L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: ETFDH oxidises ETF (reduced) to ETF, reduces CoQ to CoQH2 (Danio rerio)


name: Release of activated MAD2 from kinetochores (Homo sapiens)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Saccharomyces cerevisiae)


name: anthranilate 3-monooxygenase (deaminating) activity


name: (2S)-3-(4-hydroxyphenyl)-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]propanoate + H2O2 + H(+) => N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-tyrosine + O2


name: TGN-lysosomal vesicle coat assembly (Canis familiaris)


name: oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor


name: NIK autophosphorylates on T559 (Gallus gallus)


name: 2-(5-oxo-2,5-dihydrofuran-2-ylidene)acetate + H2O = 4-oxohex-2-enedioate + H(+)


name: E2F8 forms homodimers (Xenopus tropicalis)


name: methyl jasmonate methylesterase activity


name: MAOB inhibitors bind MAOB:FAD (Xenopus tropicalis)


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate + H2O


name: cholesterol + reduced [NADPH--hemoprotein reductase] + O2 <=> 4beta-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: oleandomycin + ATP <=> oleandomycin 2'-O-phosphate + ADP + H(+)


name: superoxide-generating NADPH oxidase activator activity


name: Activation of GT (Dictyostelium discoideum)


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Canis familiaris)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Danio rerio)


name: SIRT1 deacetylates HINT1 dimer (Canis familiaris)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Homo sapiens)


name: Recruitment of elongation factors to form elongation complex (Caenorhabditis elegans)


name: Methylthio-ribulose-P = Methylthio-ribose-P (Dictyostelium discoideum)


name: (2S)-naringenin 7-O-beta-D-glucoside + malonyl-CoA = (2S)-naringenin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: a ribonucleoside 5'-diphosphate + H2O => a ribonucleoside 5'-phosphate + phosphate + H(+)


name: Importin-8 binds AGO2:miRNA (Sus scrofa)


name: 1-acyl LPS is acylated to PS by LPSAT (Mus musculus)


name: biphenyl + NADH + O2 + H(+) => (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD(+)


name: Phosphorylation of MEF2 proteins by p38 (Schizosaccharomyces pombe)


name: Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Caenorhabditis elegans)


name: all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+)


name: SLC6A18 transports Gly from extracellular region to cytosol (Danio rerio)


name: ganglioside GQ1b alpha + CMP + H(+) => a ganglioside GT1balpha + CMP-N-acetyl-beta-neuraminate


name: Assembly of EGFR complex in clathrin-coated vesicles (Drosophila melanogaster)


name: Defective ARSB does not hydrolyse C4S/C6S chains (Homo sapiens)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Rattus norvegicus)


name: L-lysine efflux transmembrane transporter activity


name: 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O => 1-dodecanoyl-sn-glycerol + phosphocholine + H(+)


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Homo sapiens)


name: activation of protein linear polyubiquitination


name: S-(2E,6E)-farnesyl-L-cysteine + O2 + H2O <=> (2E,6E)-farnesal + L-cysteine + H2O2


name: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate


name: tricarboxylic acid transmembrane transporter activity


name: SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Mus musculus)


name: (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA = (2E,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + H2O


name: BGN binds Collagen types I, VI, (IX) (Canis familiaris)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Caenorhabditis elegans)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => quiannulatene + diphosphate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in) => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out)


name: Casein kinase II phosphorylates PTEN (Rattus norvegicus)


name: an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Bos taurus)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA


name: taurohyodeoxycholate(out) + 2 Na(+)(out) = taurohyodeoxycholate(in) + 2 Na(+)(in)


name: 4'-O-methylnorbelladine + S-adenosyl-L-homocysteine + H(+) => norbelladine + S-adenosyl-L-methionine


name: DKK promotes clathrin-dependent internalization of LRP6 (Rattus norvegicus)


name: N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: SUMOylation of TOP1 with SUMO1 (Rattus norvegicus)


name: intermembrane phosphatidylcholine transfer activity


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Bos taurus)


name: D-tyrosyl-tRNA(Tyr) + H2O => D-tyrosine + tRNA(Tyr)


name: 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP + H(+) => O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Homo sapiens)


name: NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) (Homo sapiens)


name: USP9X binds Ub:PEX5L (Drosophila melanogaster)


name: [trehalose-6-phosphate synthase]-L-cysteine + S-adenosyl-L-methionine => [trehalose-6-phosphate synthase]-S-methyl-L-cysteine + S-adenosyl-L-homocysteine + H(+)


name: AKR1B1 reduces Glc to D-sorbitol (Danio rerio)


name: a neolactoside nLc6Cer(d18:1(4E)) + GDP-beta-L-fucose => a neolactoside V(3)-alpha-Fuc-nLc6Cer(d18:1(4E)) + GDP + H(+)


name: MAP2Ks phosphorylate MAPK at the Golgi membrane (Saccharomyces cerevisiae)


name: 1,2-dihexadecanoyl-sn-glycero-3-CDP + 1D-myo-inositol 3-phosphate => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)


name: L-histidyl-L-alpha-amino acid(out) <=> L-histidyl-L-alpha-amino acid(in)


name: 7alpha-hydroxycholesterol + NADP(+) => 7-oxocholesterol + NADPH + H(+)


name: RBP3 regulates atROL taken up by Muller cells (Sus scrofa)


name: (9Z,12Z)-octadecadienoyl-CoA + malonyl-CoA + H(+) => (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA


name: indirect flight muscle actin ubiquitination


name: scutellarein + S-adenosyl-L-methionine <=> scutellarein 4'-methyl ether + S-adenosyl-L-homocysteine + H(+)


name: SCD5 desaturates ST-CoA to OLE-CoA (Saccharomyces cerevisiae)


name: a long-chain fatty acyl-CoA + acetyl-CoA <=> a long-chain 3-oxo-fatty acyl-CoA + CoA


name: D-glutamine + acetyl-CoA <=> N-acetyl-D-glutamine + CoA + H(+)


name: (S)-cyanohydrin carbonyl-lyase (cyanide forming) activity


name: (2S)-2-aminobutanoate + 3-phenylpyruvate => 2-oxobutanoate + L-phenylalanine


name: ERBB4s80:ESR1 binds PGR gene promoter (Homo sapiens)


name: CHSY1 transfers GalNAc to chondroitin (Rattus norvegicus)


name: (1R,3R)-chrysanthemal + NAD(+) + H2O <=> (1R,3R)-chrysanthemate + NADH + 2 H(+)


name: 1-nitroglycerol + nitrite + NADP(+) => 1,3-dinitroglycerol + NADPH


name: poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends


name: N-acetyl-S-methyl-L-cysteine + FMNH2 + O2 <=> (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H2O + H(+)


name: PIAS1 SUMOylates DDX5 with SUMO2 (Drosophila melanogaster)


name: prostaglandin A2 + glutathione = prostaglandin A2-S-(S)-glutathione


name: ULK complex translocates to the ER (Rattus norvegicus)


name: POMGNT2 transfers GlcNAc to Man-DAG1 (Xenopus tropicalis)


name: thiocyanate + H2O2 + H(+) => hypothiocyanous acid + H2O


name: KIT mutants:PI3K catalyze synthesis of PIP3 (Homo sapiens)


name: Partial autophosphorylation of PAK-2 at  Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 (Homo sapiens)


name: pyridoxamine + oxaloacetate = pyridoxal + L-aspartate


name: 4alpha-hydroxyformyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) => 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: sucrose transmembrane transporter activity


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Bos taurus)


name: NR2E1 associated with transcription repressors binds PTEN promoter (Homo sapiens)


name: carbamoyl phosphate + putrescine => N-carbamoylputrescine + phosphate + H(+)


name: Phosphorylation of NBS1 by ATM (Gallus gallus)


name: an aldehyde + 2 Fe(II)-[cytochrome c] + 2 H(+) => a primary alcohol + 2 Fe(III)-[cytochrome c]


name: Isomerization of GlcNAc6P to GlcNAc1P (Canis familiaris)


name: Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)


name: (R)-lavandulyl diphosphate + diphosphate => 2 dimethylallyl diphosphate


name: NTRK2 phosphorylates FRS2 (Homo sapiens)


name: Interaction of Tie2 and Shp2 (Rattus norvegicus)


name: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate (Homo sapiens)


name: The p75NTR:NgR:MDGI binds RHOA-GDI (Rattus norvegicus)


name: Decreased Muscular System Substance P Activity


name: nicotinamide + H2O => nicotinate + NH4(+)


name: Beclin-1 complex phosphorylates PtdIns (Canis familiaris)


name: 2 (2E,6E,10E)-geranylgeranyl diphosphate + NADPH + H(+) = all-trans-lycopaoctaene + 2 diphosphate + NADP(+)


name: 2-(2,4-dihydroxy-6-oxidobenzoyl)-5-hydroxy-3-methylbenzenolate + S-adenosyl-L-methionine => griseophenone D + S-adenosyl-L-homocysteine + H(+)


name: butan-1-ol + acetyl-CoA => butyl acetate + CoA


name: SLC26A4 transports I- from cytosol to extracellular region (Gallus gallus)


name: oxidoreductase activity, oxidizing metal ions with flavin as acceptor


name: NOC2L binds TP53 (Drosophila melanogaster)


name: inhibition of malate dehydrogenase (NADP, decarboxylating)


name: UDP-4-dehydro-beta-L-rhamnose + NADPH + H(+) => UDP-beta-L-rhamnose + NADP(+)


name: inhibition of p52-dependent NF-kappaB signaling


name: (E)-4-coumaroyl-CoA + NADPH + H(+) => dihydro-4-coumaroyl-CoA + NADP(+)


name: an N(1)-methyladenosine in tRNA + 2-oxoglutarate + O2 <=> an adenosine in tRNA + formaldehyde + succinate + CO2


name: (11R)-carlactonoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+) => (11R)-19-oxocarlactone + reduced [NADPH--hemoprotein reductase] + O2


name: Trimming of peptides by IRAP in endocytic vesicles (Mus musculus)


name: LINC01139 facilitates PTK6 autophosphorylation (Sus scrofa)


name: PTPN12 dephosphorylates EGFR at Y1172 (Y1148) (Homo sapiens)


name: Activation of PP2A by Xylulose-5-phosphate (Homo sapiens)


name: USF1 is phosphorylated by p-MAPK14 (Sus scrofa)


name: DVL is bound by the CUL3:KLHL12:RBX1 ubiquitin ligase complex (Rattus norvegicus)


name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: Beta-catenin is released from the destruction complex (Rattus norvegicus)


name: an acyl-CoA + glycine <=> an N-acylglycine + CoA + H(+)


name: a 2'-deoxyribonucleoside + ATP = a 2'-deoxyribonucleoside 5'-phosphate + ADP + H(+)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(R)-HDHA to AT-RvD3 or AT-RvD4 (Danio rerio)


name: alpha-D-Gal-(1->6)-beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + H2O => beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + D-galactose


name: uridine-5'-aldehyde + L-threonine => (5'S,6'S)-C-glycyluridine + acetaldehyde


name: L-lysyl-[lipoyl-carrier protein] + (R)-lipoate + ATP <=> N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)


name: Autocatalytic activation of MMP1 (Caenorhabditis elegans)


name: Type XII and XIV collagens associate with type I and type II fibrils (Danio rerio)


name: Addition of galactose to Core 6 glycoprotein (Gallus gallus)


name: rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity


name: cytidine(56) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(56) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: LIPT2 transfers octanoyl group to GCSH (Saccharomyces cerevisiae)


name: 3,5-dihydroxy-4-methylanthranilyl-[aryl-carrier protein] + NAD(+) + H2O => 3-hydroxy-4-methylanthranilyl-[aryl-carrier protein] + NADH + O2 + H(+)


name: stevioside + UDP + H(+) => rubusoside + UDP-alpha-D-glucose


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)


name: N(1),N(8)-bis(coumaroyl)-spermidine + 2 CoA + 2 H(+) => 2 (E)-4-coumaroyl-CoA + spermidine


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Danio rerio)


name: (20S)-ginsenoside Re + H2O <=> (20S)-ginsenoside Rg1 + L-rhamnopyranose


name: DIMBOA + D-glucose => DIMBOA beta-D-glucoside + H2O


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Bos taurus)


name: (9Z,12Z)-octadecadienoate + glycerol + H(+) => 2-(9Z,12Z-octadecadienoyl)-glycerol + H2O


name: regulation of IRE1-mediated unfolded protein response


name: ARSA removes sulfate from PSAP(195-273):Sulfatide (Rattus norvegicus)


name: an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = N,1-diacyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Rattus norvegicus)


name: protodeoxyviolaceinate + NADH + 2 O2 + 2 H(+) = proviolacein + CO2 + NAD(+) + 2 H2O


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Mus musculus)


name: 4-methoxybenzoate + ATP + NADPH + H(+) = 4-methoxybenzaldehyde + AMP + diphosphate + NADP(+)


name: N-terminal L-alanyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-alanyl-[protein] + CoA + H(+)


name: L-glutamyl-[protein] + NAD(+) = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide


name: CAD hexamer transforms CAP to N-carb-L-Asp (Caenorhabditis elegans)


name: 5-deoxy-5-amino-3-dehydroshikimate => 3-amino-5-hydroxybenzoate + H2O + H(+)


name: a 1,2-diacyl-3-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine <=> an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine + a 1,2-diacylglycerol


name: CDK1 phosphorylates LPIN (Canis familiaris)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Xenopus tropicalis)


name: 9 malonyl-CoA + acetyl-CoA + S-adenosyl-L-methionine + 13 NADPH + 20 H(+) <=> soppiline A + S-adenosyl-L-homocysteine + 9 CO2 + 13 NADP(+) + 10 CoA + 7 H2O


name: hexacosanoate(out) + ADP + phosphate + H(+) => hexacosanoate(in) + ATP + H2O


name: L-ascorbate + 2 Fe(III)-[cytochrome c] <=> L-dehydroascorbate + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: DEGS1 dehydrogenates dihydroceramide (Drosophila melanogaster)


name: Defective CYP17A1 does not 17-hydroxylate PREG (Homo sapiens)


name: Reorientation of dolichyl phosphate D-mannose in the endoplasmic reticulum membrane (Homo sapiens)


name: I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Homo sapiens)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-hexadecenoyl-CoA => 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: N-hydroxylation of 4-aminobiphenyl (Bos taurus)


name: POLZ elongates POLI-incorporated dNMP (Schizosaccharomyces pombe)


name: BRF1 Complex recruits RNA degradation activities (Bos taurus)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Canis familiaris)


name: 5alpha-dihydrotestosterone sulfate + NADPH + H(+) => (3beta,5alpha,17beta)-3-hydroxy-androstan-17-yl sulfate + NADP(+)


name: superoxide + nitric oxide = peroxynitrite


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Drosophila melanogaster)


name: (11Z)-octadecenoyl-CoA + cholesterol => cholesteryl (11Z)-octadecenoate + CoA


name: N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminosyl-(2->6)]-N-acetyl-D-galactosamine + CMP + H(+) => N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + CMP-N-acetyl-beta-neuraminate


name: 15,17(3)-seco-F430-17(3)-acid + ATP <=> coenzyme F430 + ADP + phosphate


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Danio rerio)


name: Active IKK Complex phosphorylates NF-kappa-B inhibitor  (Drosophila melanogaster)


name: a phenol + sulfate + H(+) => an aryl sulfate + H2O


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Canis familiaris)


name: ZIP7 mediates zinc efflux from the endoplasmic reticulum (Mus musculus)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-tetradecanoyl-sn-glycerol 3-phosphate + choline + H(+)


name: 1-eicosanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA => 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: Active LTK receptor binds SHC1 (Homo sapiens)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Rattus norvegicus)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] (Homo sapiens)


name: BESTs transport cytosolic HCO3- to extracellular region (Xenopus tropicalis)


name: SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Xenopus tropicalis)


name: 2-glutathionyl-2-methylbut-3-en-1-ol + 2 NAD(+) + H2O = 2-glutathionyl-2-methylbut-3-enoate + 2 NADH + 3 H(+)


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Dictyostelium discoideum)


name: negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway


name: AURKA phosphorylates TP53 (Canis familiaris)


name: IL22:p‑Y251,p‑Y301‑IL22RA1:p‑JAK1:PTPN11:IL10RB:p‑TYK2 binds PTPN11 (Canis familiaris)


name: (2R)-2-phosphoglycerate + ATP = (2R)-2,3-bisphosphoglycerate + ADP + H(+)


name: (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+) => (+)-dehydrodiconiferyl acid + 2 a quinone + H2O


name: Conversion of malonyl-CoA and acetyl-CoA to palmitate (Bos taurus)


name: Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2 (Homo sapiens)


name: UMPS dimer decarboxylates OMP to UMP (Rattus norvegicus)


name: APEH hydrolyses NAc-Ser-protein (Plasmodium falciparum)


name: CYP26A1,B1 4-hydroxylate atRA (Canis familiaris)


name: IGFBP4 binds IGF forming IGF:IGFBP4 (Rattus norvegicus)


name: Transcytosis and dissociation of botE:NTNHA (Homo sapiens)


name: Transfer of NEDD8 to AcM-UBE2M (Saccharomyces cerevisiae)


name: MDM2 polyubiquitinates RUNX3 (Gallus gallus)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Homo sapiens)


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Mus musculus)


name: fluoroacetyl-CoA + H2O = fluoroacetate + CoA + H(+)


name: N(1)-acetylspermidine + H2O <=> spermidine + acetate


name: bisucaberin + AMP + diphosphate + H(+) => bisucaberin B + ATP


name: OPC-6 + ATP + CoA = OPC-6-CoA + AMP + diphosphate


name: L-methionyl-tRNA(Met) + AMP + diphosphate => tRNA(Met) + L-methionine + ATP


name: Interaction of IRF9 with p-STAT2:p-STAT1 (Bos taurus)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Canis familiaris)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Caenorhabditis elegans)


name: Fe(II)-heme b-[protein] + nitrite + 2 H(+) => Fe(III)-heme b-[protein] + nitric oxide + H2O


name: (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + octanoyl-CoA => (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl]-glycerate + CoA


name: Branching and elongation of mother and daughter filaments (Drosophila melanogaster)


name: 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) <=> 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphate + CoA => 1-hexadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA


name: 7,8-dihydroxy benzo(a)pyrene dioxygenase activity


name: anthranilate + octanoate + H(+) => N-octanoylanthranilate + H2O


name: abscisate(in) + ATP + H2O = abscisate(out) + ADP + phosphate + H(+)


name: butan-1-ol + NADP(+) => butanal + NADPH + H(+)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Caenorhabditis elegans)


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Rattus norvegicus)


name: Release of PLCG from FCGR (Rattus norvegicus)


name: WWP2 ubiquitinates NOTCH3 (Gallus gallus)


name: inhibition of succinic acid dehydrogenase activity


name: Activated FGFR4 binds SHC1 (Rattus norvegicus)


name: Translocation of NuMA to the centrosomes (Rattus norvegicus)


name: IMP + 2 phosphate + 2 H(+) => ITP + 2 H2O


name: negative regulation of methane biosynthetic process from carbon monoxide


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Caenorhabditis elegans)


name: p-S363,S380,T573 RS6K translocates to the nucleus (Saccharomyces cerevisiae)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)


name: TIMM8:TIMM13 chaperones hydrophobic proteins (Homo sapiens)


name: xylitol + NADP(+) <=> L-xylulose + NADPH + H(+)


name: heptadecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) => trans-2-heptadecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: alpha-D-mannose derivative + alpha-D-glucose 1-phosphate + H(+) => 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H2O


name: Interaction of PECAM-1 and SHP-2 (Sus scrofa)


name: Degradation of multiubiquitinated cell cycle proteins (Sus scrofa)


name: SMAD7 binds SERPINE1 gene promoter (Homo sapiens)


name: (2E)-glutaconyl-CoA + reduced [electron-transfer flavoprotein] => glutaryl-CoA + oxidized [electron-transfer flavoprotein] + H(+)


name: a (3Z)-enoyl-CoA => a 4-saturated (2E)-enoyl-CoA


name: B-WICH recruits histone acetyltransferases (Homo sapiens)


name: RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Canis familiaris)


name: a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine


name: galactitol + NADP(+) <=> D-galactose + NADPH + H(+)


name: pre-sodorifen diphosphate + S-adenosyl-L-homocysteine + H(+) => (2E,6E)-farnesyl diphosphate + S-adenosyl-L-methionine


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O <=> sn-glycero-3-phospho-L-serine + (9Z)-octadecenoate + H(+)


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: Joining of adjacent Okazaki fragments of the C-strand (Bos taurus)