name: Formation of the 19S regulatory particle precursor (Drosophila melanogaster)


name: negative regulation of nonadec-1-ene biosynthetic process


name: nucleobase-containing compound metabolic process


name: an N(6)-methyl-2'-deoxyadenosine in DNA + 2-oxoglutarate + O2 => a 2'-deoxyadenosine in DNA + formaldehyde + succinate + CO2


name: NPM1-ALK-dependent repression of pRB phosphorylation (Homo sapiens)


name: activation of orthophosphoric diester phosphohydrolase activity


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Mus musculus)


name: 7alpha-hydroxy-3,12-dioxo-5beta-cholanate + NADP(+) = dehydrocholate + NADPH + H(+)


name: CYLD mediated deubiquitination of DDX58 (RIG-I) (Rattus norvegicus)


name: (3R)-hydroxy-(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + NADP(+) => (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + NADPH + H(+)


name: a fatty acid ester + H2O = an aliphatic alcohol + a fatty acid + H(+)


name: regulation of systemic arterial blood pressure by epinephrine


name: O(3)-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O <=> beta-D-galactosyl-(1->3)-N-acetyl-D-galactosamine + L-threonyl-[protein]


name: MICAL1 produces NADP+, H2O2 (Dictyostelium discoideum)


name: LRTOMT transfers Met to DA, forming 3MT (Mus musculus)


name: activation of nucleotide biosynthetic process


name: (2R,3S,11R)-aszonalenin + acetyl-CoA = (2R,3S,11R)-acetylaszonalenin + CoA


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Mus musculus)


name: preaspterpenacid acid I + diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate + H2O


name: a very-long-chain (2E)-enoyl-CoA + H2O2 => a very-long-chain 2,3-saturated fatty acyl-CoA + O2


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-gamma-aminobutanoate + O2 => N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-gamma-aminobutanoate


name: a (3R)-3-isocyanyl-fatty acyl-[ACP] + AMP + H(+) => a (3R)-3-isocyanyl-fatty acyl-AMP + holo-[ACP]


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ADP + phosphate + H(+) => a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ATP + H2O


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Caenorhabditis elegans)


name: JMJD1C demethylates H3K9 mono- and di-methylation (Gallus gallus)


name: catechol + nitrite + NAD(+) => nitrobenzene + NADH + O2


name: Squalene 2,3-epoxide cyclizes, forming lanosterol (Mus musculus)


name: STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Sus scrofa)


name: Activated DTOR also phosphorylates D4EBP (Drosophila melanogaster)


name: a long-chain fatty acyl-[ACP] + NADPH + H(+) => a long-chain fatty aldehyde + holo-[ACP] + NADP(+)


name: testosterone + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => 1alpha-hydroxytestosterone + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: Uncoupled eNOS favours the formation of superoxide (Saccharomyces cerevisiae)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Xenopus tropicalis)


name: hexadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => (6Z)-hexadecenoyl-[ACP] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: peptidase activity, acting on D-amino acid peptides


name: 3-phenylpyruvate + NADH + H(+) => 3-phenyllactate + NAD(+)


name: N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) + H2O <=> 2''-O-lipoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O


name: Autoproteolytic cleavage of Hh precursors (Rattus norvegicus)


name: Arachidonate is hydroxylated to 19-HETE by CYP(2) (Dictyostelium discoideum)


name: PITPNM1,2,3 exchange PI for PA (Sus scrofa)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Schizosaccharomyces pombe)


name: a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP


name: beta-phellandrene + diphosphate => (2E)-geranyl diphosphate


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] => N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] + H2O


name: angelicin + acetone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => (S)-columbianetin + reduced [NADPH--hemoprotein reductase] + O2


name: methyl-Co(III)-[methylated-thiol-specific corrinoid protein] + hydrogen sulfide => Co(I)-[methylated-thiol-specific corrinoid protein] + methanethiol


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)


name: activation of nitric-oxide synthase 2 biosynthetic process


name: GM2A binds and mobilizes ligands (Bos taurus)


name: IRE1 binds IRE1 forming dimer (Homo sapiens)


name: Activation of proMMP11 by FURIN (Rattus norvegicus)


name: 4alpha-formylzymosterol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4alpha-carboxyzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: activation of methylenetetrahydrofolate reductase (NADPH(2)) activity


name: intronic transcription regulatory region sequence-specific DNA binding


name: Recruitment of Dna2 endonuclease (Caenorhabditis elegans)


name: dideacetyl astellolide A + H2O => 7beta,14,16-trihydroxyconfertifolin + benzoate + H(+)


name: inhibition of maltoheptaose metabolic process


name: SUMOylation of TOP2A with SUMO1 (Caenorhabditis elegans)


name: Cleavage of uracil by TDG glycosylase (Danio rerio)


name: PI3P is dephosphorylated to PI by SACM1L at the Golgi membrane (Saccharomyces cerevisiae)


name: L-lysyl-glycine(in) + H(+)(in) => L-lysyl-glycine(out) + H(+)(out)


name: 6-demethylsterigmatocystin + S-adenosyl-L-methionine => sterigmatocystin + S-adenosyl-L-homocysteine + H(+)


name: ethylenediaminetriacetate + FMN + glyoxylate + H2O + 2 H(+) => EDTA + FMNH2 + O2


name: T2Rs bind bitter-tasting compounds (Mus musculus)


name: intracellularly cyclic nucleotide-activated monoatomic cation channel activity


name: cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Homo sapiens)


name: L-methionine transmembrane transporter activity


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Sus scrofa)


name: OSBPs transport 25OH-CHOL from ER membrane to plasma membrane (Canis familiaris)


name: urokinase plasminogen activator + urokinase plasminogen activator receptor (uPAR) -> urokinase plasminogen activator:uPAR (Rattus norvegicus)


name: [(3R)-hydroxybutanoate](n) + H2O = [(3R)-hydroxybutanoate](n-2) + (3R)-hydroxybutanoate dimer + H(+)


name: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 <=> 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O + H(+)


name: a long-chain fatty acyl-CoA + alpha,alpha-trehalose <=> a 2-O-(long-chain fatty acyl)-alpha,alpha-trehalose + CoA


name: O-phospho-L-seryl-[protein] + GDP + H(+) => L-seryl-[protein] + GTP


name: L-proline + L-tryptophan + 2 ATP + NADPH <=> (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + 2 AMP + 2 diphosphate + NADP(+) + H2O + H(+)


name: 1,2,3-tri-(9Z)-hexadecenoylglycerol + H2O <=> 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + (9Z)-hexadecenoate + H(+)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Mus musculus)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Xenopus tropicalis)


name: N-acetyl-beta-alanine + H2O <=> beta-alanine + acetate


name: Interleukin-35 translocates from the ER lumen to the extracellular region (Sus scrofa)


name: Cytosolic HIF1AN (FIH1) hydroxylates asparagine residues of Hypoxia-inducible Factor Alpha (HIF1A,HIF2A) (Gallus gallus)


name: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine + acetate => UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetyl-alpha-D-glucosamine + H2O


name: heterotrimeric G-protein GTPase, gamma-subunit


name: (20S)-ginsenoside F2 + UDP-alpha-D-glucose => (20S)-ginsenoside Rd + UDP + H(+)


name: SLC25A1 exchanges CIT and MAL (Xenopus tropicalis)


name: L-threonine(out) + L-glutamine(in) + Na(+)(out) = L-threonine(in) + L-glutamine(out) + Na(+)(in)


name: (S)-methylmalonyl-CoA + NADP(+) = acryloyl-CoA + CO2 + NADPH


name: a glycerophospholipid(in) + ATP + H2O <=> a glycerophospholipid(out) + ADP + phosphate + H(+)


name: Phosphorylation of phospho- (Ser45, Thr41) beta-catenin  at Ser37 by GSK-3 (Gallus gallus)


name: Ras:GTP binds p120-RasGAP (Canis familiaris)


name: aldehydo-D-mannose + phosphoenolpyruvate + H2O => 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + phosphate


name: thyroxine + 3'-phosphoadenylyl sulfate = thyroxine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: PLA2G2A binds bacterial phospholipids (Drosophila melanogaster)


name: ATG10 dissociates from ATG12:ATG5 (Canis familiaris)


name: cyclopentylamine + NADP(+) + H2O => cyclopentanone + NH4(+) + NADPH + H(+)


name: intramolecular oxidoreductase activity, other intramolecular oxidoreductases


name: anthocyanin A3 + malonyl-CoA => anthocyanin A5 + CoA


name: CMP or TMP or UMP + H2O => cytidine, thymidine, or uridine + orthophosphate [NT5E] (Canis familiaris)


name: GDP-4-dehydro-alpha-D-rhamnose + L-glutamate => 2-GDP-(2S,3S,6R)-3-hydroxy-5-amino-6-methyl-3,6-dihydro-2H-pyran + 2-oxoglutarate + H2O + H(+)


name: trans-4-hydroxy-L-proline + a quinone => (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)


name: L1 trans-homophilic interaction (Caenorhabditis elegans)


name: hexylamine + NAD(+) + H2O <=> hexanal + NH4(+) + NADH + H(+)


name: 2xTPK1:Mg2+ phosphorylates THMN (Bos taurus)


name: peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium


name: PAPS is dephosphorylated to APS (Mycobacterium tuberculosis)


name: LMCD1 binds GATA6, sequestering it (Caenorhabditis elegans)


name: Fall Back to Closed Pre-initiation Complex (Homo sapiens)


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Caenorhabditis elegans)


name: Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 (Rattus norvegicus)


name: ORC2 binds ORC3 (Dictyostelium discoideum)


name: AcK-NFE2L2 binds the BCL2 gene (Homo sapiens)


name: tRNA(Gly) + glycine + ATP <=> glycyl-tRNA(Gly) + AMP + diphosphate


name: D-glucose(in) + H(+)(out) => D-glucose(out) + H(+)(in)


name: myo-inositol(out) + 2 Na(+)(out) <=> myo-inositol(in) + 2 Na(+)(in)


name: MARK3 phosphorylates KSR1 (Drosophila melanogaster)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Canis familiaris)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Drosophila melanogaster)


name: cholate + NADP(+) => 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADPH + H(+)


name: (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + reduced [NADPH--hemoprotein reductase] + O2 <=> 5-dehydro-6-demethoxyfumagillol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: VAV2 is a GEF for Rho/Rac family kinases (Sus scrofa)


name: tigecycline + NADPH + O2 + H(+) = 11a-hydroxytigecycline + NADP(+) + H2O


name: Activation of Rho by LARG and PDZ-RhoGEF (Mus musculus)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Mus musculus)


name: MMACHC dealkylates RCbl (Dictyostelium discoideum)


name: prostaglandin A1 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy prostaglandin A1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Sus scrofa)


name: c-FOS activation by phospho ERK1/2 (Xenopus tropicalis)


name: G6PC hydrolyzes G6P to Glc and Pi (liver) (Bos taurus)


name: [(2->6)-alpha-D-glucosyl-(1->4)-N-acetyl-alpha-D-neuraminosyl](n) + n acetyl-CoA => [(2->6)-alpha-D-glucosyl-(1->4)-N,O(9)-diacetyl-alpha-D-neuraminosyl](n) + n CoA


name: an N-acyl-sphingoid 1-phosphoethanolamine + CMP + H(+) => CDP-ethanolamine + an N-acyl-sphingoid base


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Homo sapiens)


name: 3-O-(alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + UDP + H(+)


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Homo sapiens)


name: HPDL dioxygenates HPPA (Dictyostelium discoideum)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Xenopus tropicalis)


name: S-adenosyl-L-methionine = (S)-azetidine-2-carboxylate + S-methyl-5'-thioadenosine + H(+)


name: PI(4,5)P2 is dephosphorylated to PI5P by TMEM55B in the nucleus (Danio rerio)


name: Exocytosis of secretory granule membrane proteins (Mus musculus)


name: L-cysteinyl-[protein] + fumarate => S-(2-succinyl)-L-cysteinyl-[protein]


name: SPRY2 is serine phosphorylated in response to MAPK activation (Gallus gallus)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Plasmodium falciparum)


name: THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)


name: 20cho-LTB4 is oxidised to 20cooh-LTB4 by CYP4F2/4F3 (Bos taurus)


name: decanoyl-[ACP] + 4 malonyl-CoA + AH2 + S-adenosyl-L-methionine + 3 H(+) => 2,4-dihydroxy-3-methyl-6-(2-oxoundecyl)benzaldehyde + holo-[ACP] + A + S-adenosyl-L-homocysteine + 4 CO2 + 4 CoA + H2O


name: NMRK1 phosphorylates NR to yield NMN (Homo sapiens)


name: an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP <=> an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)


name: L-phenylalanocholate + taurine => taurocholate + L-phenylalanine


name: FADK1 interaction with DCC (Homo sapiens)


name: LTA4 is converted to LTC4 by LTC4S (Dictyostelium discoideum)


name: D-threonine + O2 + H2O = (S)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+)


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Homo sapiens)


name: dTDP-beta-L-mycarose + erythronolide B => 3-O-alpha-L-mycarosylerythronolide B + dTDP + H(+)


name: botA:SV2:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Bos taurus)


name: Activated FGFR1 phosphorylates FRS2 (Homo sapiens)


name: KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 (Rattus norvegicus)


name: SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Schizosaccharomyces pombe)


name: (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate <=> 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: cortisone + NADPH + H(+) => cortisol + NADP(+)


name: keto-L-sorbose + O2 <=> 5-dehydro-D-fructose + H2O2


name: OCT3 mediates renal uptake of organic cations (Mus musculus)


name: glycolaldehyde + pyruvate => 2-dehydro-3-deoxy-L-arabinonate


name: NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycerol + ATP => a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)


name: Autoglucosylation of GYG1 complexed with GYS1-a (Mus musculus)


name: MUC20 binds MET and inhibits GRB2 binding (Rattus norvegicus)


name: Ubiquitinated IkB is degraded (Sus scrofa)


name: glycine-cleavage system L-protein activity


name: 2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + phosphate + 2 H2O


name: sulochrin + 2 FADH2 + 2 chloride + 2 O2 <=> dihydrogeodin + 2 FAD + 4 H2O + H(+)


name: vibriobactin biosynthetic process, peptide formation


name: FOXM1 binds CDC25A promoter (Homo sapiens)


name: D-ribose 5-phosphate + uracil <=> psi-UMP + H2O


name: 2-ethyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP(+) => (2E)-2-ethylidene-4-hydroxy-5-methylfuran-3(2H)-one + NADPH + H(+)


name: (S)-2-hydroxyglutarate + A <=> AH2 + 2-oxoglutarate


name: a ganglioside GD1a (d18:1(4E)) + N-acetylneuraminate => a ganglioside GT1a (d18:1(4E)) + H2O


name: 7-dehydrocholesterol + NADP(+) = 7-dehydrodesmosterol + NADPH + H(+)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + CoA => sn-glycero-3-phosphoethanolamine + an acyl-CoA


name: CHEK1 is recruited to resected DNA DSBs (Drosophila melanogaster)


name: K+-independent Li+/Ca2+ exchanger transport (Drosophila melanogaster)


name: (2E)-tetradecenoyl-[ACP] + NADPH + H(+) => tetradecanoyl-[ACP] + NADP(+)


name: GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Rattus norvegicus)


name: (8S)-8-amino-7-oxononanoate + L-lysyl-[protein] + CO2 = (S)-2-amino-6-oxohexanoyl-[protein] + (7R,8S)-8-amino-7-(carboxyamino)nonanoate + 2 H(+)


name: PIAS4 SUMOylates VHL with SUMO1 (Danio rerio)


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Caenorhabditis elegans)


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Sus scrofa)


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Dictyostelium discoideum)


name: epidermal growth factor catabolic process


name: (2Z,6E)-farnesyl diphosphate => (-)-beta-curcumene + diphosphate


name: 2-methylbutanamine + NAD(+) + H2O => 2-methylbutanal + NH4(+) + NADH + H(+)


name: negative regulation of serine-type endopeptidase activity


name: HLA-G specific inhibitory MHC class Ib receptor activity


name: 11-deoxycortisol + 2 reduced [adrenodoxin] + O2 + 2 H(+) <=> cortisol + 2 oxidized [adrenodoxin] + H2O


name: HP1 alpha binds Histone H3K9(me)3 (Caenorhabditis elegans)


name: PDE6 hydrolyses cGMP to GMP (Sus scrofa)


name: Interaction of Erp57 with MHC class I HC (Homo sapiens)


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Danio rerio)


name: p-STAT1 and p-STAT4 dissociate from IL12RB2:IL6ST receptor (Mus musculus)


name: (3R)-beta-leucine + NAD(+) + H2O <=> 4-methyl-3-oxopentanoate + NH4(+) + NADH + H(+)


name: STAT1,STAT3,STAT6 phosphorylation (Rattus norvegicus)


name: 6-phospho-D-gluconate + NADP(+) => 6-phospho-2-dehydro-D-gluconate + NADPH + H(+)


name: citrate + ATP + CoA => (3S)-citryl-CoA + ADP + phosphate


name: p-Y-STAT3:p-STAT5 translocates to the nucleus (Bos taurus)


name: an aromatic aldehyde + O2 + H2O = an aromatic carboxylate + H2O2 + H(+)


name: NAT1,2 acetylate APAP-Cys to APAP-Mer (Danio rerio)


name: cAMP-dependent protein kinase regulator activity


name: Phosphorylation of Cdh1 by Cyclin B1:Cdc2 (Mus musculus)


name: regulation of succinic dehydrogenase activity


name: SLCO1B1 transports ALB:(GCCA,TCCA) from extracellular region to cytosol (Sus scrofa)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine


name: GNRHR binds GNRHR peptide antagonists (Homo sapiens)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Saccharomyces cerevisiae)


name: Recruitment of ITK to SLP-76 (Bos taurus)


name: 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA => nonadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate


name: 20-hydroxy prostaglandin E2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => prostaglandin E2 + reduced [NADPH--hemoprotein reductase] + O2


name: 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate 9-phosphate + phosphate => aldehydo-D-mannose 6-phosphate + phosphoenolpyruvate + H2O


name: L-alanyl-L-aspartate(out) + 2 H(+)(out) = L-alanyl-L-aspartate(in) + 2 H(+)(in)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: Activation of TAK1-TAB2 complex (Sus scrofa)


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z,12Z)-octadecadienoyl-CoA


name: CDK1 phosphorylates VCPIP1 (Homo sapiens)


name: UCHL3, SENP8 cleave NEDD8 (Canis familiaris)


name: D-erythrose 4-phosphate + beta-D-fructose 6-phosphate => D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate


name: I(1,3)P2 is dephosphorylated into I1P by MTMR7 (Homo sapiens)


name: HSD17B2 oxidises estradiol (E2) to estrone (E1) (Rattus norvegicus)


name: (E,E)-piperoyl-CoA + AMP + diphosphate => (E,E)-piperate + ATP + CoA


name: down regulation of activation of JAK2 kinase activity


name: 26S proteasome degrades TP73 polyubiquitinated by ITCH (Homo sapiens)


name: α2-agonists bind ADRA2A,B,C (Mus musculus)


name: Organic Anion Transporting Polypeptide 1B1 Inhibitors


name: L-saccharopine + NADP(+) + H2O <=> (S)-2-amino-6-oxohexanoate + L-glutamate + NADPH + H(+)


name: N(6)-succinyl-L-lysyl-[protein] + CoA + H(+) => succinyl-CoA + L-lysyl-[protein]


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Rattus norvegicus)


name: N-formylmethanofuran + H2O => methanofuran + formate


name: Addition of the first glucose to the N-glycan precursor by ALG6 (Canis familiaris)


name: Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase (Xenopus tropicalis)


name: cephaeline + S-adenosyl-L-homocysteine + H(+) => 7'-O-demethylcephaeline + S-adenosyl-L-methionine


name: DENND3 exchanges GTP for GDP on RAB12 (Dictyostelium discoideum)


name: Activated protein C cleaves Factor Va intermediate form for Factor Va (Canis familiaris)


name: BLK gene expression is stimulated by the complex of RUNX1 and ELF1, ELF2 or PAX5 (Homo sapiens)


name: alpha-nootkatol + reduced [NADPH--hemoprotein reductase] + O2 = (+)-nootkatone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: canthaxanthin + 2 A + 3 H2O => echinenone + 2 AH2 + 2 O2


name: GGPS1 hexamer transfers IPPP to DMAPP (Homo sapiens)


name: Formation of ORC(2-5) complex (Dictyostelium discoideum)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Schizosaccharomyces pombe)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Sus scrofa)


name: (2'R)-atrovenetin + S-adenosyl-L-methionine = deoxyherqueinone + S-adenosyl-L-homocysteine + H(+)


name: an N-alkylglycine + O2 + H2O => an alkylamine + glyoxylate + H2O2


name: ESR1 binds to TFF1 gene promoter (Danio rerio)


name: 4-guanidinobutanal + NAD(+) + H2O => 4-guanidinobutanoate + NADH + 2 H(+)


name: alpha-maltoheptaose + phosphate = alpha-maltohexaose + alpha-D-glucose 1-phosphate


name: N-octadecanoyl-(4R)-hydroxysphinganine + CoA + H(+) => (4R)-hydroxysphinganine + octadecanoyl-CoA


name: (E)-3-(indol-3-yl)acrylate + NH4(+) => L-tryptophan


name: 4-formylbenzenesulfonate + NAD(+) + H2O = 4-sulfobenzoate + NADH + 2 H(+)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Canis familiaris)


name: activation of tyrosine 3-hydroxylase activity


name: [hyaluronan](n) = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine + H2O


name: Unphosphorylated nucleoprotein translocates to the plasma membrane (Homo sapiens)


name: Recognition and Binding of Core Promoter Elements by TFIID (Mus musculus)


name: L-2-aminopentanoate + kynurenate + H2O => 2-oxopentanoate + L-kynurenine


name: Removal of remaining Flap from the C-strand (Homo sapiens)


name: L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate


name: PGLYRP1 binds bacterial peptidoglycan (Sus scrofa)


name: N-acetyl-D-muramate 6-phosphate + H2O <=> N-acetyl-D-glucosamine 6-phosphate + (R)-lactate


name: p-4Y-SIRPA:CD47 binds SKAP2 (Canis familiaris)


name: glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Sus scrofa)


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Xenopus tropicalis)


name: taurochenodeoxycholate + reduced [NADPH--hemoprotein reductase] + O2 <=> taurohyocholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: TBC1D14 binds RAB11 and ULK1 (Homo sapiens)


name: Nectin-2:Nectin 3 trans heterodimer interaction (Canis familiaris)


name: Phosphorylation of YAP by LATS1 (Caenorhabditis elegans)


name: RAC2:GTP binds NOX2 complex (Rattus norvegicus)


name: nitrous oxide + H2O = 2 e(-) + 2 nitric oxide + 2 H(+)


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Sus scrofa)


name: Release of endostatin-like peptides (Mus musculus)


name: preaustinoid A2 + 2-oxoglutarate + O2 <=> preaustinoid A3 + succinate + CO2 + H2O


name: Association of procollagen type XII (Caenorhabditis elegans)


name: N(3)-methylcytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-homocysteine + H(+) => cytidine(32) in tRNA(Arg)(CCU) + S-adenosyl-L-methionine


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Xenopus tropicalis)


name: Interaction of Tie2 and Grb14 (Mus musculus)


name: Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 (Sus scrofa)


name: xylitol + ATP = xylitol 5-phosphate + ADP + H(+)


name: lovastatin + H2O <=> monacolin J + (S)-2-methylbutanoate + H(+)


name: 1-O-decyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-decyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O


name: 1-O-(9Z)-octadecenoyl-2-O-acetyl-sn-glycero-3-phosphocholine + H2O <=> 2-acetyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)


name: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) <=> 2 cob(II)yrinate a,c diamide + FMNH2


name: DGAT2L6,L7P transfer acyl group from acyl-CoA to DAG, forming TAG (Danio rerio)


name: Phosphorylated FOXO3 translocates to the nucleus (Homo sapiens)


name: Receptor CCR10 binds CCL27 and 28 ligands (Homo sapiens)


name: Expression of HES7 in presomitic mesoderm (Homo sapiens)


name: LDH tetramer reduces PYR to LACT (Mus musculus)


name: Disassociation of CLIP from MHC II (Mus musculus)


name: phenylsuccinate + succinyl-CoA <=> 3-phenylsuccinyl-CoA + succinate


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)


name: PTK2 binds activated EGFR (Rattus norvegicus)


name: soyasapogenol B 3-O-beta-D-glucuronate + UDP + H(+) => soyasapogenol B + UDP-alpha-D-glucuronate


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1,2-dihexadecanoyl-sn-glycerol + phosphocholine + H(+)


name: positive regulation of galactotriose transport


name: L-alanine(out) + chloride(out) + 2 Na(+)(out) <=> L-alanine(in) + chloride(in) + 2 Na(+)(in)


name: Cyclophosphamide is 4-hydroxylated by CYP2B6 (Drosophila melanogaster)


name: p-4Y-PLCG1 dissociates from activated FGFR1 (Homo sapiens)


name: COPI vesicle uncoating at the ER (Schizosaccharomyces pombe)


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine <=> 1,3,3'-tri-O-methyl-4alpha-mannobiose + S-adenosyl-L-homocysteine + H(+)


name: Binding of IP3 to IP3 receptor (Gallus gallus)


name: COMT transfers Met to DOPAC to form HVA (Sus scrofa)


name: IL37:IL18R1 binds SIGIRR (Canis familiaris)


name: (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA => (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol


name: Type I Na+-coupled phosphate co-transport (Canis familiaris)


name: an (S)-2-haloacid + H2O <=> a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Schizosaccharomyces pombe)


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Bos taurus)


name: (7S)-hydroperoxy-(4Z,8E,10Z,13Z,16Z,19Z)-docosahexaenoate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2


name: XDH oxidizes hypoxanthine to form xanthine (Dictyostelium discoideum)


name: 4-methylthiopropyl glucosinolate S-oxygenase activity


name: alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+) => alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate


name: 13-hydroperoxy-(9Z,11E)-octadecadienoate => (9Z,12Z)-octadecadienoate + O2


name: N-(9Z-octadecenoyl)-L-tryptophan + H2O <=> L-tryptophan + (9Z)-octadecenoate


name: Exocytosis of azurophil granule lumen proteins (Schizosaccharomyces pombe)


name: Formation of P-TEFb complex (Mus musculus)


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: IC-asc-C9 + ATP + H(+) => IC-asc-C9-AMP + diphosphate


name: NADH + H2O => reduced beta-nicotinamide D-ribonucleotide + AMP + 2 H(+)


name: 10-hydroperoxy-(8E)-octadecenoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-hexadecanoyl-2-(10-hydroperoxy-8E-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: 2xPPCS ligates PPanK with Cys (Saccharomyces cerevisiae)


name: (R)-glycerate + NAD(+) => 3-hydroxypyruvate + NADH + H(+)


name: aldehydo-D-glucose 6-phosphate + L-lysyl-[protein] <=> N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein] + H2O


name: PILRA binds PIANP, COLLEC12 trimer, NPDC1, CLEC4G (Homo sapiens)


name: PDE6 hydrolyses cGMP to GMP (Bos taurus)


name: HMGCR dimer binds statins (Homo sapiens)


name: N-methylputrescine + O2 + H2O => 4-methylaminobutanal + H2O2 + NH4(+)


name: PTPN3 binds p-T183,Y185 MAPK12 (Rattus norvegicus)


name: IL6ST is tyrosine phosphorylated (Rattus norvegicus)


name: BSG:MCTs cotransport LACT, H+ from cytosol to extracellular region (Sus scrofa)


name: 4'-phosphooxetanocin A + H2O => oxetanocin A + phosphate


name: SRC family kinases phosphorylate ERBB2 (Sus scrofa)


name: maleate(in) + 2-oxoglutarate(out) = maleate(out) + 2-oxoglutarate(in)


name: Tyrosine phosphorylation of CRMPs by Fes (Homo sapiens)


name: Activated CIT binds KIF14 and PRC1 (Drosophila melanogaster)


name: phenylpropanonitrile + 2 H2O <=> 3-phenylpropanoate + NH4(+)


name: rifamycin O + H2O2 => rifamycin B + O2 + 2 H(+)


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Bos taurus)


name: L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine <=> N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: VEGFA-165 dimer binds VEGFR2 dimer (Mus musculus)


name: Excision of 8-oxoguanine by OGG1 glycosylase (Homo sapiens)


name: SLC26A1,2 cotransport SO4(2-), H+ from extracellular region to cytosol (Canis familiaris)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Mus musculus)


name: D-proline(out) + H(+)(out) => D-proline(in) + H(+)(in)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CDP-choline => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 O2 => (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E,19Z)-docosahexaenoate


name: SLC22A18 exchanges extracellular organic cations for cytosolic H+ (Bos taurus)


name: Interaction of DAP12 and CLM7 (Homo sapiens)


name: Caspase-mediated cleavage of Rock-1 (Bos taurus)


name: (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + O2 = (8S)-hydroperoxy-(14S,15R)-epoxy-(5Z,9E,11Z)-eicosatrienoate


name: CYP2D6 4-hydroxylates debrisoquine (Mus musculus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Rattus norvegicus)


name: 2'-deoxyinosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine


name: 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadecadienoyl)-sn-glycerol + H2O => 2-(9Z,12Z-octadecadienoyl)-glycerol + (9Z)-octadecenoate + H(+)


name: heptanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxononanoyl-[ACP] + CO2 + CoA


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O <=> 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + 2 reduced [2Fe-2S]-[ferredoxin] + H(+)


name: Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a  'closed-loop' conformation (Canis familiaris)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Xenopus tropicalis)


name: 6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate = 4-deoxy-4-sulfo-D-erythrose + D-xylulose 5-phosphate


name: HSP90 binds TBK1 and IRF3 (Canis familiaris)


name: Protesomal degradation of K48polyUb-TRAF3 (Homo sapiens)


name: acarbose 7(IV)-phosphate + ADP + H(+) => acarbose + ATP


name: The high affinity receptor complex binds to G-protein (Homo sapiens)


name: Interaction of integrin alphaVbeta3 with PECAM1 (Bos taurus)


name: ATP-dependent cobalt transmembrane transporter activity


name: NOTCH3 binds activated EGFR (Mus musculus)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Sus scrofa)


name: GLB1 hydrolyses linker chain(2) (Bos taurus)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: CHSY1 transfers GlcA to chondroitin (Homo sapiens)


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Mus musculus)


name: long-chain fatty acid [acyl-carrier-protein] ligase activity


name: Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Gallus gallus)


name: NT5C2 tetramer phosphorylates RBV (Bos taurus)


name: L-serine(in) + Na(+)(in) <=> L-serine(out) + Na(+)(out)


name: Keratin type I binds keratin type II (Bos taurus)


name: cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(4447) in 28S rRNA + S-adenosyl-L-homocysteine + H(+)


name: pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + ATP + H(+) => 1-(5-O-phospho-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl adenylate + diphosphate


name: trans-resveratrol + O2 = 3,5-dihydroxybenzaldehyde + 4-hydroxybenzaldehyde


name: Recognition of AAUAAA sequence by CPSF (Rattus norvegicus)


name: glycolate + NADH + 2 H(+) => glycolaldehyde + NAD(+) + H2O


name: (R)-pantoate + NADP(+) => 2-dehydropantoate + NADPH + H(+)


name: GUSB tetramer hydrolyses CS/HS precursor (Drosophila melanogaster)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Saccharomyces cerevisiae)


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)


name: Insertion of correct bases opposite the lesion by POLH (Plasmodium falciparum)


name: CYP3A4 oxidizes PREDN,PREDL (Bos taurus)


name: p-S473-AKT1 phosphorylates ESR1 on serine-167 (Rattus norvegicus)


name: RNA Polymerase II CTD (phosphorylated) binds to CE (Saccharomyces cerevisiae)


name: activation of 4-hydroxybiphenyl UDP-glucuronosyltransferase activity


name: adenylyl MoO2(OH)-molybdopterin cofactor => adenylyl MoO3-molybdopterin cofactor


name: EFCAB7:IQCE binds EVC2:EVC (Xenopus tropicalis)


name: N-acyl-1-deoxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => N-acyl-1-deoxysphing-14Z-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Association of procollagen type XVIII (Sus scrofa)


name: all-trans-antheraxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> all-trans-violaxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Drosophila melanogaster)


name: D-erythrose 4-phosphate + L-lysyl-[protein] <=> N(6)-(4-O-phospho-D-erythrulosyl)-L-lysyl-[protein] + H2O


name: GYS2 catalyzes the incorporation of phosphoglucose into glycogen-GYG2 (Drosophila melanogaster)


name: 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) <=> 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: negative regulation of gamma-aminobutyric acid catabolic process


name: kojibiose + phosphate => beta-D-glucose 1-phosphate + D-glucose


name: S-sulfanyl-L-cysteine + tRNA(Cys) + ATP <=> (S)-sulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate


name: 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate + H2O <=> 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate


name: XPC binds RAD23 and CETN2 (Gallus gallus)


name: Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)


name: 2-deoxy-D-ribose 5-phosphate + hypoxanthine => dIMP + H2O


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Homo sapiens)


name: 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene + A => 1'-hydroxy-demethylspheroidene + AH2


name: 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine => 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate


name: Duplex siRNA is loaded into Argonaute (Rattus norvegicus)


name: Arachidonate is epoxidated to 14,15-EET by CYP(5) (Rattus norvegicus)


name: 4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold (Homo sapiens)


name: IRAK interacts with TRAF6 (Homo sapiens)


name: Release Of ADP From Myosin (Rattus norvegicus)


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Rattus norvegicus)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Canis familiaris)


name: SUMOylation of HDAC1 with SUMO1 (Dictyostelium discoideum)


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Mus musculus)


name: Translocation of tetracosapentaenoyl-CoA to peroxisomes (Xenopus tropicalis)


name: Phosphorylation of GAB2 by SFKs (Homo sapiens)


name: Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Gallus gallus)


name: POU5F1 (OCT4), SOX2, NANOG bind the FGF2 promoter (Homo sapiens)


name: GPER:Heterotrimeric G-protein Gs binds ESTG (Sus scrofa)


name: Caspase-7 translocates to the nucleus (Homo sapiens)


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Bos taurus)


name: Epsin family proteins bind ubiquitinated cargo (Rattus norvegicus)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Rattus norvegicus)


name: Interaction of other tyrosine kinases with p-KIT (Xenopus tropicalis)


name: sn-glycerol 3-phosphate + FAD + H(+) <=> dihydroxyacetone phosphate + FADH2


name: putrescine + acetyl-CoA = N-acetylputrescine + CoA + H(+)


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + H2O <=> N-hexadecanoylsphing-4-enine + beta-D-glucose


name: Apelin receptor binds to apelin (Homo sapiens)


name: L-lysine(in) + ADP + phosphate + H(+) => L-lysine(out) + ATP + H2O


name: MECP2 binds PPARG gene promoter (Homo sapiens)


name: KIR3DL2 interacting with HLA-A3 (Homo sapiens)


name: Furin cleaves pro-protein C to protein C (Danio rerio)


name: a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + H2O => (2E,4S)-4,5-dihydroxypent-2-enal + a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H(+)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + 3'-phosphoadenylyl sulfate => beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + adenosine 3',5'-bisphosphate + H(+)


name: JNK-dependent inhibition of TP53 ubiquitination (Homo sapiens)


name: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADPH + O2 + H(+) => 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP(+) + H2O


name: a 1-acyl-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + O2 = a 1-acyl-2-(15-hydroperoxy-8Z,11Z,13E-eicosatrienoyl)-sn-glycero-3-phospho-(1D-myo-inositol)


name: K(+)(out) + Na(+)(in) + ATP + H2O <=> K(+)(in) + Na(+)(out) + ADP + phosphate + H(+)


name: glutamate uptake by astrocytes (Bos taurus)


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Mus musculus)


name: ABC-type capsular-polysaccharide transporter activity


name: verruculide C + AH2 + O2 => verruculide C epoxide + A + H2O


name: glycerol + phosphate => glycerol 2-phosphate + H2O


name: (E)-coniferaldehyde + NADPH + H(+) => (E)-coniferol + NADP(+)


name: N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+) => N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + UDP-N-acetyl-alpha-D-glucosamine


name: Interaction of other adapter proteins with p-KIT (Sus scrofa)


name: malonate(out) + succinate(in) = malonate(in) + succinate(out)


name: (+)-dehydrodiconiferyl acid + 2 a quinone + H2O => (+)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NADH + H(+) <=> 4-pyridoxate + NAD(+)


name: inhibition of diglyceride kinase activity


name: Rabenosyn-5 connects  Rab5 to VPS-45 (Drosophila melanogaster)


name: USP25 deubiquitinates DDX58 (Mus musculus)


name: N-methyl-2-oxoglutaramate + H2O = methylamine + 2-oxoglutarate


name: tauronorcholate(out) + 2 Na(+)(out) <=> tauronorcholate(in) + 2 Na(+)(in)


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Gallus gallus)


name: negative regulation of tyrosine 3-monooxygenase activity


name: 2,4-diacetylphloroglucinol + H2O => 2-acetylphloroglucinol + acetate


name: inhibition of violaceol II biosynthetic process


name: Phosphorylation of Cdc25A at Ser-123 by Chk2 (Bos taurus)


name: (-)-menthol + NADPH + O2 + H(+) => 1,4-menthane-3,8-diol + NADP(+) + H2O


name: (2R,3R)-tartrate + H(+) = (R)-glycerate + CO2


name: Formation of ORC(1-5) complex (Schizosaccharomyces pombe)


name: Mevalonate-5-phosphate is further phosphorylated (Danio rerio)


name: Association of Cyclin A:Cdk2 with Cdh1 (Drosophila melanogaster)


name: (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate => (5S,6S)-epoxy-(18R)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O


name: cycloartenol + S-adenosyl-L-methionine => cyclolaudenol + S-adenosyl-L-homocysteine + H(+)


name: N-tetracosanoyl-(4R)-hydroxysphing-(8Z)-enine + CoA + H(+) => (4R)-hydroxysphing-(8Z)-enine + tetracosanoyl-CoA


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Caenorhabditis elegans)


name: Autocleavage of ESPL1 (Separase) (Dictyostelium discoideum)


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Schizosaccharomyces pombe)


name: 17alpha-hydroxypregn-4-en-3,11,20-trione-21-al + NADH + H(+) => cortisone + NAD(+)


name: N(alpha)-methyl-L-histidine + S-adenosyl-L-methionine => N(alpha),N(alpha)-dimethyl-L-histidine + S-adenosyl-L-homocysteine + H(+)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Homo sapiens)


name: Prolactin-releasing hormone receptor binds PRH (Mus musculus)


name: down regulation of coenzyme Q9 biosynthesis


name: SLC29A3 transports nucleosides from lysosomal lumen to cytosol (Caenorhabditis elegans)


name: (R)-4'-phosphopantothenate + ADP + H(+) => (R)-pantothenate + ATP


name: Formation of the outer ring of the 20S core particle (Homo sapiens)


name: Activated FGFR3 phosphorylates PLCG1 (Mus musculus)


name: guanosine(in) + H(+)(in) => guanosine(out) + H(+)(out)


name: activation of transferrin receptor binding


name: cysteine-type endopeptidase activity involved in apoptotic process


name: 5-epi-5-F2t-IsoP + UDP-alpha-D-glucuronate <=> 5-epi-5-F2t-IsoP-glucuronide + UDP + H(+)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Caenorhabditis elegans)


name: plasminogen + histidine-rich glycoprotein -> plasminogen:histidine-rich glycoprotein (Bos taurus)


name: SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Bos taurus)


name: Increased Lipid Derived Immunologically Active Molecule Production


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Xenopus tropicalis)


name: Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3 (Gallus gallus)


name: PGE2 is converted to PGF2a by CBR1 (Mus musculus)


name: secondary active cyanate transmembrane transporter activity


name: glycochenodeoxycholate(out) + ADP + phosphate + H(+) => glycochenodeoxycholate(in) + ATP + H2O


name: IRAK1 induces oligomerisation of TRAF6 (Bos taurus)


name: a 2,3-saturated fatty acid + H2O2 = a 3-hydroxy fatty acid + H2O


name: 2',3'-cGAMP(in) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(out) => 2',3'-cGAMP(out) + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide(in)


name: STAB2:ligand is endocytosed (Gallus gallus)


name: Caspase mediated cleavage of C-IAP1 (Gallus gallus)


name: aminomethylphosphonate + glyoxylate + H2O2 + H(+) => glyphosate + O2 + H2O


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Canis familiaris)


name: (S)-N-methylbulbocapnine + S-adenosyl-L-homocysteine + H(+) => (S)-bulbocapnine + S-adenosyl-L-methionine


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Canis familiaris)


name: GGPS1 hexamer transfers IPPP to DMAPP (Saccharomyces cerevisiae)


name: Uptake of Noradrenaline (Rattus norvegicus)


name: G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC (Homo sapiens)


name: cyanidin 3-O-rutinoside + UDP-alpha-D-glucose => cyanidin 3-O-rutinoside 5-O-beta-D-glucoside + UDP + H(+)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Xenopus tropicalis)


name: N-[omega-(9Z,12Z)-octadecadienoyloxy]-acylsphin-4-enine + O2 = N-acyl (9R)-hydroperoxy-(10E,12Z)-octadecadienoate octadecasphing-4E-enine


name: Interaction of integrin alphaEbeta7 with Cadherin-1 (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + L-serine <=> a 1,2-diacyl-sn-glycero-3-phospho-L-serine + ethanolamine


name: phytol + tetradecanoyl-CoA => tetradecanoate phytyl ester + CoA


name: an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + 2-oxoglutarate + O2 => a 2'-deoxycytidine in double-stranded DNA + formaldehyde + succinate + CO2 + H(+)


name: (1S)-3-methyl-cyclohexylamine + NAD(+) + H2O = 3-methylcyclohexanone + NH4(+) + NADH + H(+)


name: alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose => alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: 3-methyl-1,2-didehydro-2,3-dihydrobotryococcene + S-adenosyl-L-methionine = 3,20-dimethyl-1,2,21,22-tetradehydro-2,3,20,21-tetrahydrobotryococcene + S-adenosyl-L-homocysteine + H(+)


name: Keratin type I binds keratin type II (Mus musculus)


name: dodecyl sulfate + 2-oxoglutarate + O2 <=> dodecanal + sulfate + succinate + CO2 + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+) => a CDP-1,2-diacyl-sn-glycerol + choline


name: a 1-acyl-2-(9Z)-enoyl-sn-glycero-3-phospholipid + S-adenosyl-L-methionine => a 1-acyl-2-(9-cyclopronane)-acyl-sn-glycero-3-phospholipid + S-adenosyl-L-homocysteine + H(+)


name: SLC7A9:SLC3A1 exchanges L-Arg, CySS-, L-Lys for L-Leu (Mus musculus)


name: Increased Central Nervous System Aspartate Activity


name: 1,2,3-trihydroxybenzene + O2 = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + 2 H(+)


name: (d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Homo sapiens)


name: a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + L-seryl-[protein] <=> 3-O-(alpha-D-mannosyl)-L-seryl-[protein] + a di-trans,poly-cis-dolichyl phosphate + H(+)


name: kainate(in) + ATP + H2O <=> kainate(out) + ADP + phosphate + H(+)


name: Hydration of delta2-tetracosaheptaenoyl-CoA to 3-hydroxy tetracosahexaenoyl-CoA (Mus musculus)


name: Formation of the 19S regulatory particle base precursor (Plasmodium falciparum)


name: F1Fo ATP synthase dimerizes (Canis familiaris)


name: (4Z,15Z)-bilirubin IXalpha + NADP(+) => biliverdin IXalpha + NADPH + H(+)


name: inosine 5'-monophosphate (IMP) + H2O => inosine + orthophosphate (Gallus gallus)


name: ERCC5 and RPA bind TC-NER site (Bos taurus)


name: S-methyl-5'-thioadenosine + phosphate => S-methyl-5-thio-alpha-D-ribose 1-phosphate + adenine


name: Mitochondrial FPGS-1 transforms THF to THFPG (Saccharomyces cerevisiae)


name: N(6)-propanoyl-L-lysyl-[protein] + NAD(+) + H2O => 3''-O-propanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: N(6)-methyl-L-lysyl(4)-[histone H3] + 2-oxoglutarate + O2 = L-lysyl(4)-[histone H3] + formaldehyde + succinate + CO2


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Sus scrofa)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO4 (Drosophila melanogaster)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Mus musculus)


name: 2-hydroxyglutarate + FAD + H(+) = FADH2 + 2-oxoglutarate


name: gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate + ATP <=> L-glutamyl-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+)


name: 3,4-dimethoxy-L-phenylalanine => 3,4-dimethoxy-(E)-cinnamate + NH4(+)


name: ALDH4A1 dimer dehydrogenates 4-OH-L-glutamate semialdehyde to 4-OH-L-glutamate (Rattus norvegicus)


name: Cleavage of Procaspase‑9 to caspase‑9 (Danio rerio)


name: activation of TRAIL-induced apoptotic signaling pathway


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Canis familiaris)


name: DNA polymerases delta, epsilon or kappa bind the TC-NER site (Schizosaccharomyces pombe)


name: NFE2L2 binds the SRXN1 gene (Homo sapiens)


name: Activated PLC gamma dissociates from the PDGF receptor (Canis familiaris)


name: 2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate <=> 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: TFIIH binds GG-NER site to form a verification complex (Caenorhabditis elegans)


name: lipid A hexaacyl 1-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) = lipid A 1,4'-bis(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol


name: CSN polymer binds CaPO4 (Canis familiaris)


name: cannabinerolate + O2 = Delta(9)-tetrahydrocannabinolate + H2O2


name: 3'-dephospho-CoA(in) + ADP(out) => 3'-dephospho-CoA(out) + ADP(in)


name: Recruitment of p190RhoGEF to p-FAK (Caenorhabditis elegans)


name: N-acetylserotonin + H2O <=> serotonin + acetate


name: Autocatalytic activation of proMMP2 (Gallus gallus)


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Canis familiaris)


name: IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Homo sapiens)


name: Deubiquitination of FancD2 (Gallus gallus)


name: TFAM binds to mitochondrial promoters (Rattus norvegicus)


name: sn-glycerol 3-phosphate(out) + ATP + H2O => sn-glycerol 3-phosphate(in) + ADP + phosphate + H(+)


name: Release of STAT1 dimer from active receptor unit (Mus musculus)


name: Liganded G12/13-activating GPCRs bind inactive heterotrimeric G-protein G12/13 (Caenorhabditis elegans)


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Homo sapiens)


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Canis familiaris)


name: ATP-dependent DNA/DNA annealing activity


name: DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Xenopus tropicalis)


name: flavin-containing compound catabolic process


name: Aquaporin-4 passively transports water out of cell (Canis familiaris)


name: 4-chloro-L-lysine + AH2 + O2 => L-2-amino-4-chloropent-4-enoate + formaldehyde + A + NH4(+) + H2O


name: SMAC (DIABLO) forms dimer (Rattus norvegicus)


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphate = 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphate + CoA


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Rattus norvegicus)


name: Conjugation of SUMO1 to UBA2:SAE1 (Gallus gallus)


name: Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)


name: Exocytosis of secretory granule lumen proteins (Dictyostelium discoideum)


name: pyridoxamine 5'-phosphate + 2-oxoglutarate => pyridoxal 5'-phosphate + D-glutamate


name: thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators (Sus scrofa)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Bos taurus)


name: POLRMT polymerizes RNA primer for mitochondrial L strand replication (Gallus gallus)


name: RHOB translocates to the endosome membrane (Mus musculus)


name: type 1 metabotropic GABA receptor binding


name: a 1-O-alkylglycerone 3-phosphate + NADPH + H(+) <=> a 1-O-alkyl-sn-glycero-3-phosphate + NADP(+)


name: N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA => N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA


name: MAPK6 is degraded by the 26S proteasome (Rattus norvegicus)


name: all-trans-4,4'-diapolycopen-4-al + A + H2O => all-trans-4,4'-diapolycopen-4-oate + AH2 + H(+)


name: naphtopyrone YWA1 + H2O = naphthalene-1,3,6,8-tetrol + acetoacetate + H(+)


name: COQ3 methylates DeMQ10H2 (Xenopus tropicalis)


name: gibberellin A12 + 2 2-oxoglutarate + 3 O2 + H(+) <=> gibberellin A9 + 2 succinate + 3 CO2 + 2 H2O


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Mus musculus)


name: TYRP1 oxidises DHICA to IQCA (Rattus norvegicus)


name: Increased Enteric Nervous System Epinephrine Activity


name: PP5 dephosphorylates RAF1 S338 (Bos taurus)


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Canis familiaris)


name: GPCR signaling pathway involved in cooperative behavior


name: Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Gallus gallus)


name: 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Saccharomyces cerevisiae)


name: SIRT5 deacetylates Cytochrome C (Xenopus tropicalis)


name: Gq-BTK complex dissociates to Active BTK and Gq (Canis familiaris)


name: N-terminal L-methionyl-L-glutamyl-[protein] + acetyl-CoA => N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] + CoA + H(+)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Rattus norvegicus)


name: Collagen type I binds integrin alpha11beta1 (Mus musculus)


name: DNA nucleases unhook the interstrand crosslink (ICL) (Sus scrofa)


name: Formation of hydroxylysyl-pyridinoline cross-links (Xenopus tropicalis)


name: ERCC6 binds stalled RNA Pol II (Mus musculus)


name: (2S)-3-methyl-2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]butanoate + H2O + H(+) <=> 2-dehydro-D-glucose + L-valine


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Bos taurus)


name: USP8 deubiquitinates RNF128 (Gallus gallus)


name: N-acetyl-D-galactosamine + O2 <=> N-acetyl-D-galactosamino-1,5-lactone + H2O2


name: RUNX1:CBFB binds CREBBP (Caenorhabditis elegans)


name: CA4:Zn2+ hydrates CO2 to HCO3- (Rattus norvegicus)


name: intermembrane glycolipid transporter activity


name: MIB2 ubiquitinates RIPK1 at K377, K604, K634 (Canis familiaris)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)


name: a 2,3-di-O-phytanyl-sn-glycerophospholipid + AH2 + 2 S-adenosyl-L-methionine <=> a macrocyclic archaeaol phospholipid + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+)


name: Heparin binds PKR (Drosophila melanogaster)


name: PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Rattus norvegicus)


name: SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Bos taurus)


name: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Proteasome mediated degradation of COP1 (Canis familiaris)


name: Hv1 Mediated H+ Permeability (Gallus gallus)


name: Recruitment of TRAF6 to CBM complex by binding to MALT1 (Sus scrofa)


name: L-cysteinyl-5'-AMP + holo-[peptidyl-carrier protein] => L-cysteinyl-[peptidyl-carrier protein] + AMP + H(+)


name: 1'-carboxy-chondrochloren B + FAD + 2 H(+) <=> chondrochloren B + FADH2 + CO2


name: HRH1 binds HRH1 inverse agonists (Rattus norvegicus)


name: menaquinone-7 + succinate <=> menaquinol-7 + fumarate


name: N(2)-(1-deoxy-beta-D-fructopyranos-1-yl)-L-lysine + O2 + H2O <=> (1-deoxy-D-fructos-1-yl)amine + 6-amino-2-oxohexanoate + H2O2


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4 (Bos taurus)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Gallus gallus)


name: cytidine(32) in tRNA(Ser) + S-adenosyl-L-methionine => N(3)-methylcytidine(32) in tRNA(Ser) + S-adenosyl-L-homocysteine + H(+)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Drosophila melanogaster)


name: 2-methoxy-6-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = 6-methoxy-3-methyl-2-all-trans-octaprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H(+)


name: MITF-M-dependent CCNB1 gene expression (Homo sapiens)


name: all-trans-4-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2


name: ecdysone + hexadecanoyl-CoA => ecdysone hexadecanoate + CoA


name: riboflavin + H2O + H(+) = lumichrome + ribitol


name: (4Z,15Z)-bilirubin IXalpha + D-glucuronate + H(+) => (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside + H2O


name: guanosine(46) in tRNA + S-adenosyl-L-methionine => N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine


name: p-S207 KARS1 dimer synthesizes A(5')p4(5')A (Canis familiaris)


name: Cleavage of thymine by 5-methylcytosine G/T mismatch specific glycosylase (Gallus gallus)


name: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate + H2O => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate => preasperterpenoid A + diphosphate


name: beta-amyrin + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = oleanolate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: NEXT3 is cleaved to produce NICD3 (Xenopus tropicalis)


name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Bos taurus)


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Xenopus tropicalis)


name: 3-(hydrohydroxyphosphoryl)pyruvate + acetyl-CoA + H2O = phosphinomethylmalate + CoA + H(+)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Rattus norvegicus)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Canis familiaris)


name: p-PKR dimer phosphorylates DHX9 (Caenorhabditis elegans)


name: CDC42 GEFs activate CDC42 (Xenopus tropicalis)


name: inhibition of 3-oxosphinganine synthetase activity


name: Formation of the MLL4 complex (Caenorhabditis elegans)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)


name: L-amino acyl-L-seryl-[protein] + ATP <=> (S,S)-2-(C-substituted-aminomethyl)-4-acyl-2-oxazoline-[protein] + ADP + phosphate + H(+)


name: metoxuron + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> 3-(3-chloro-4-methoxylphenyl)-1-methylurea + formaldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out) => 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in)


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Canis familiaris)


name: SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Canis familiaris)


name: UVSSA:USP7 deubiquitinates ERCC6 (Danio rerio)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Canis familiaris)


name: PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Caenorhabditis elegans)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Saccharomyces cerevisiae)


name: 1-(9Z-octadecenoyl)-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => di-(9Z)-octadecenoylglycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: (-)-dehydrodiconiferyl acid + 2 a quinone + H2O <=> (-)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: ASIC3 channel blockers bind ASIC3 trimer (Sus scrofa)


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Saccharomyces cerevisiae)


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Mus musculus)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Schizosaccharomyces pombe)


name: Zymosterone (cholesta-8(9),24-dien-3-one) is reduced to zymosterol (cholesta-8(9),24-dien-3beta-ol) (Sus scrofa)


name: Integrin alpha7beta1 binds Laminin-211, 221, 411, 512, 521 (Rattus norvegicus)


name: griseophenone D + S-adenosyl-L-methionine => griseophenone C + S-adenosyl-L-homocysteine


name: IL1R1:IL1:IL1RAP binds MYD88 homodimer (Rattus norvegicus)


name: S-methyl-5'-thioadenosine + H2O + H(+) = S-methyl-5'-thioinosine + NH4(+)


name: E2F1 binds the ORC1 gene promoter (Homo sapiens)


name: hexadecanoyl-CoA + glycine + H(+) => 1-deoxymethyl-3-dehydrosphinganine + CO2 + CoA


name: inhibition of GDP-dissociation stimulator activity


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Canis familiaris)


name: N-(3,4-dichlorophenyl)malonamate + CoA => 3,4-dichloroaniline + malonyl-CoA


name: Oxytocin receptor bind oxytocin (Sus scrofa)


name: a nucleoside 3',5'-cyclic phosphate + H2O = a nucleoside 5'-phosphate + H(+)


name: UDP-alpha-D-galactose + D-glucose <=> lactose + UDP + H(+)


name: N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine + H2O <=> N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl + D-alanine


name: Cytosolic DUSPs dephosphorylate MAPKs (Plasmodium falciparum)


name: (R)-lavandulol + diphosphate => (R)-lavandulyl diphosphate + H2O


name: TOP2A gene gene expression is repressed by the DREAM complex (Homo sapiens)


name: glutathioselenol + NADPH => hydrogenselenide + glutathione + NADP(+)


name: B3GALNT1 transfers GalNAc to Gb3Cer to form Gb4Cer (Canis familiaris)


name: MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin (Sus scrofa)


name: SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Caenorhabditis elegans)


name: N(4)-acetylcytidine + H2O = cytidine + acetate + H(+)


name: sedoheptulose + ATP => D-sedoheptulose 7-phosphate + ADP + H(+)


name: flavokermesate + UDP-alpha-D-glucose <=> flavokermesate 7-C-beta-D-glucoside + UDP + 2 H(+)


name: 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate => phytyl diphosphate + homogentisate + H(+)


name: a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol


name: ACLY tetramer transforms CIT to Ac-CoA (Mus musculus)


name: delayed rectifier potassium channel activity


name: a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a (9Z,12E)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: USP13 deubiquitinates BECN1,USP10 (Dictyostelium discoideum)


name: Monofunctional chemotherapeutic alkylating drugs produce 7-methylguanine in dsDNA (Homo sapiens)


name: positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Canis familiaris)


name: a polyvinyl alcohol + 2n Fe(III)-[cytochrome c] => an oxidized polyvinyl alcohol + 2n Fe(II)-[cytochrome c] + 2n H(+)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Schizosaccharomyces pombe)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole => 12-epi-fischerindole U


name: GPR31 is a receptor for 12(S)-HETE (Canis familiaris)


name: Deubiquitinated PTEN translocates to the cytosol (Caenorhabditis elegans)


name: salicylaldehyde + O2 + H2O = salicylate + H2O2 + H(+)


name: PIAS2-2 SUMOylates THRA with SUMO3 (Homo sapiens)


name: BESTs transport cytosolic HCO3- to extracellular region (Bos taurus)


name: GBF1 stimulates ARF nucleotide exchange (Plasmodium falciparum)


name: α2-agonists bind ADRA2A,B,C (Canis familiaris)


name: dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + CoA + H(+) => dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + acetyl-CoA


name: GADD45A binds AURKA (Drosophila melanogaster)


name: aurachin B + NAD(+) + H2O <=> 4-hydroxy-2-methyl-3-oxo-[(2E,6E)-farnesyl]-3,4-dihydroquinoline 1-oxide + NADH


name: IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Rattus norvegicus)


name: p-DAPP1 (p-BAM32) binds PLCG2 (Gallus gallus)


name: Monoubiquitination of PCNA (Gallus gallus)


name: transmembrane receptor protein tyrosine kinase inhibitor activity


name: G/U mismatch-specific uracil-DNA glycosylase activity


name: ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Dictyostelium discoideum)


name: a 2'-deoxyribonucleoside 5'-triphosphate + H2O <=> a 2'-deoxyribonucleoside 5'-diphosphate + phosphate + H(+)


name: Recruited STAT5 is phosphorylated (Rattus norvegicus)


name: SESN1,SESN1 bind SQSTM1 and KEAP1 (Bos taurus)


name: Orexin 2 receptor can bind orexin-B neuropeptide (Sus scrofa)


name: PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Gallus gallus)


name: IRAK4 binds to the activated TLR7/8 or 9 receptor:MyD88 complex  (Homo sapiens)


name: p-4Y-PLCG1 dissociates from activated FGFR3 (Homo sapiens)


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + ATP <=> 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-2-O-phosphoxylosyl)-L-seryl-[protein] + ADP + H(+)


name: Dimerization of phosphorylated IRF3/IRF7 (Rattus norvegicus)


name: SARS-CoV-2 nsp6 binds TBK1 (Homo sapiens)


name: MDP elicits a NOD2 response (Danio rerio)


name: UBP43 binds IFNAR2 and prevents JAK1 interaction (Gallus gallus)


name: glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Sus scrofa)


name: beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose <=> alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-1-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: labd-13Z-ene-9,15,16-triol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => peregrinol + reduced [NADPH--hemoprotein reductase] + O2


name: holo-[aryl-carrier protein] + 3,4-dihydroxybenzoate + ATP <=> 3,4-dihydroxybenzoyl-[aryl-carrier protein] + AMP + diphosphate


name: L-alanine + O2 + H2O <=> pyruvate + H2O2 + NH4(+)


name: 2-acyl LPG is acylated to PG by LPGAT (Homo sapiens)


name: GLUT2 (SLC2A2) tetramer transports Glc from extracellular region to cytosol (Rattus norvegicus)


name: SRD5A3 dehydrogenates TEST to DHTEST (Dictyostelium discoideum)


name: cytidine(72) in tRNA(Thr) + S-adenosyl-L-methionine = 5-methylcytidine(72) in tRNA(Thr) + S-adenosyl-L-homocysteine + H(+)


name: Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Mus musculus)


name: CYP4F11 16-hydroxylates 3OH-PALM (Sus scrofa)


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)


name: a guanosine in RNA + methylglyoxal => an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA


name: linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity


name: PSMG1 binds PSMG2 (Dictyostelium discoideum)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Dictyostelium discoideum)


name: FKBP1A binds tacrolimus (Xenopus tropicalis)


name: a 3-oxoacyl-CoA + succinate => a 3-oxo acid + succinyl-CoA


name: Phosphorylation and activation of CHEK2 by ATM (Bos taurus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine


name: BIL binds GSTA1, FABP1 (Caenorhabditis elegans)


name: "Transferring alkyl or aryl groups, other than methyl groups"


name: 4 malonyl-CoA + acetyl-CoA + 5 NADPH + 9 H(+) <=> 7-methylmellein + 3 CO2 + 5 NADP(+) + 5 CoA + 4 H2O


name: orcinol + NADH + O2 + H(+) = 2,3,5-trihydroxytoluene + NAD(+) + H2O


name: Syndecans 2, (4) bind TGFB1 (Bos taurus)


name: glycolate + GMP + H(+) => N(2)-(1-hydroxy-2-oxoethyl)-GMP + H2O


name: ACP phosphopantetheine attachment site binding


name: GTSE1 binds MAPRE1 (EB1) at microtubule plus ends (Canis familiaris)


name: D-xylotriose + O2 => D-xylotriono-1,5-lactone + H2O2


name: FURIN translocates to the plasma membrane (Plasmodium falciparum)


name: N(3)-fumaramoyl-(S)-2,3-diaminopropanoate + L-valine + ATP = dapdiamide A + ADP + phosphate + H(+)


name: ZIP6 and ZIP14 mediate zinc influx into cells (Rattus norvegicus)


name: Increased Smooth Muscle Substance P Activity


name: lutein + O2 <=> (3R,6R)-hydroxy-alpha-ionone + (3R)-3-hydroxy-10'-apo-beta-carotenal


name: CDC42:GTP binds CBL:Beta-Pix (Drosophila melanogaster)


name: 2,3-dihydroxybenzoate + H(+) <=> catechol + CO2


name: Arachidonate is oxidised to 12S-HpETE by ALOX12/15 (Rattus norvegicus)


name: N-acetyl-alpha-D-glucosamine 1-phosphate <=> N-acetyl-D-glucosamine 6-phosphate


name: dITP + H2O <=> dIMP + diphosphate + H(+)


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Mus musculus)


name: a 1-acyl-2-hexadecanoyl-glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: MME:Zn2+ binds sacubitrilat (Caenorhabditis elegans)


name: 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA => 1-(9Z,12Z-octadecadienoyl)-glycerol + (9Z)-octadecenoyl-CoA


name: TBC1D14 binds RAB11 and ULK1 (Mus musculus)


name: 6-oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O => 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Caenorhabditis elegans)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Dictyostelium discoideum)


name: a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine => a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: G alpha (q):RGS dissociates to inactive G alpha (q) (Danio rerio)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Mus musculus)


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Bos taurus)


name: CPN, CPB2 cleave C3a, C5a (Rattus norvegicus)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + GTP = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + GMP + diphosphate


name: "RNA 3'-terminal-phosphate cyclase (GTP)"


name: inhibition of polyadenylate nucleotidyltransferase activity


name: nsp14 acts as a cap N7 methyltransferase to modify SARS-CoV-2 gRNA complement (minus strand) (Homo sapiens)


name: CaMKK phosphorylates CAMK4 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + GDP-alpha-D-mannose => a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP + H(+)


name: reduced nicotinamide adenine dinucleotide hydrate dehydratase activity


name: Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Gallus gallus)


name: Formation of eIF2:GDP:eIF2B intermediate (Saccharomyces cerevisiae)


name: 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+) => L-dopa + O2


name: SUMOylation of TOP1 with SUMO1 (Homo sapiens)


name: hexadecanoate + holo-[ACP] + H(+) => hexadecanoyl-[ACP] + H2O


name: PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane (Caenorhabditis elegans)


name: Cleavage of C3 by C3 convertases (Sus scrofa)


name: ORC1 binds to H4K20me2 (Plasmodium falciparum)


name: Addition of GlcNAc to position 4 by N-acetylglucosaminyltransferase (GnT)-IV (Sus scrofa)


name: PTEN gene transcription is stimulated by TP53, EGR1, PPARG, ATF2, MAF1, and inhibited by NR2E1, SALL4, MECOM, SNAI1, SNAI2, JUN (Homo sapiens)


name: inhibition of dehydroaustinol biosynthetic process


name: Formation of Processive Complex on the C-strand of the telomere (Canis familiaris)


name: CAK-mediated phosphorylation of Cyclin A:Cdc2 complexes (Gallus gallus)


name: N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+) => N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine


name: c-FOS activation by phospho ERK1/2 (Caenorhabditis elegans)


name: pseudotropine + NADP(+) = tropinone + NADPH + H(+)


name: CBL ubiquitinates Sprouty (Mus musculus)


name: ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Xenopus tropicalis)


name: gibberellin A19 + 2-oxoglutarate + O2 => gibberellin A17 + succinate + CO2 + H(+)


name: catechol-containing compound catabolic process


name: RAB9 GEFs exchange GTP for GDP on RAB9 (Gallus gallus)


name: positive regulation of coenzyme F420-dependent nitroreductase activity


name: geranylgeranyl diphosphate = tuberculosinyl diphosphate


name: dodecane + reduced [NADPH--hemoprotein reductase] + O2 <=> 5-dodecanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 2-deoxy-D-glucose 6-phosphate + NADP(+) = 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + H(+)


name: SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Canis familiaris)


name: Binding of STAT1 to p-IFNGR1 (Danio rerio)


name: guanosine(1145) in 16S rRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(1145) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)


name: PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Canis familiaris)


name: 7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) => 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)


name: Autoglucosylation of GYG2 complexed with GYS2-b (Bos taurus)


name: GDP-alpha-D-perosamine + acetyl-CoA <=> GDP-N-acetyl-alpha-D-perosamine + CoA + H(+)


name: RHOC GEFs activate RHOC (Canis familiaris)


name: PON1,2,3:Ca2+ dimers hydrolyse 5-HETEL to 5-HETE (Xenopus tropicalis)


name: ilicicolin A epoxide + NADPH + O2 + H(+) <=> 16-hydroxy-ilicicolin A epoxide + NADP(+) + H2O


name: p-S407,Y641-STAT6 is dimerized (Drosophila melanogaster)


name: 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O = 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)


name: COQ5 methylates MDMQ10H2 (Saccharomyces cerevisiae)


name: Decreased Midbrain Nerve Growth Factor Activity


name: cytidine(967) in 16S rRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(967) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + ADP + phosphate + H(+) => C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine + ATP


name: rebaudioside D + UDP + H(+) => rebaudioside E + UDP-alpha-D-glucose


name: O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+) => L-seryl-[I-kappa-B protein] + ATP


name: UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-hex-4-ulose + H2O => UDP-N-acetyl-alpha-D-glucosamine


name: oxidized coenzyme F420-1 + GDP + phosphate + H(+) => oxidized coenzyme F420-0 + GTP + L-glutamate


name: hexanal + hydrogen cyanide <=> (2S)-2-hydroxyheptanenitrile


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Bos taurus)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Sus scrofa)


name: SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)


name: 12,20-dihydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 12-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2


name: L-asparagine, sodium:proton antiporter activity


name: L-asparagine(out) + Na(+)(out) + H(+)(in) = L-asparagine(in) + Na(+)(in) + H(+)(out)


name: Beclin-1 complex translocates to the ER (Rattus norvegicus)


name: N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + 2 A + 2 H2O = L-lysyl(4)-[histone H3] + 2 formaldehyde + 2 AH2


name: beta-alanine + NH4(+) => beta-alaninamide + H2O


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Danio rerio)


name: VPS4 binds ESCRT-III assemblies at nuclear envelope (NE) fenestrations (Gallus gallus)


name: Phosphorylation of Cyclin B1 in the CRS domain (Sus scrofa)


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Homo sapiens)


name: DDX41 ubiquitination by TRIM21 (Mus musculus)


name: ent-copalyl diphosphate + H2O => ent-manool + diphosphate


name: RAB21 GEFs exchange GTP for GDP on RAB21 (Mus musculus)


name: N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] + H2O <=> N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate


name: Estrogen-responsive KPNA2 gene transcription (Homo sapiens)


name: DAG kinase produces phosphatidic acid from DAG (Drosophila melanogaster)


name: Hypophosphorylation of RNA Pol II CTD by FCP1P protein (Mus musculus)


name: 2-phenylacetate + reduced [NADPH--hemoprotein reductase] + O2 = (2-hydroxyphenyl)acetate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 2,3-dihydrobiochanin A + NADP(+) <=> biochanin A + NADPH + 2 H(+)


name: SHP2 dephosphorylates Tyr 992 on EGFR (Rattus norvegicus)


name: Phosphorylation of YAP by LATS2 (Homo sapiens)


name: SUMOylation of NFKB2 with SUMO1 (Mus musculus)


name: Secreted CD14 binds LPS (Canis familiaris)


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine (Xenopus tropicalis)


name: ergosterol + a carboxylate + H(+) => ergosteryl ester + H2O


name: xanthohumol + S-adenosyl-L-methionine = 4-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)


name: NSF ATPase activity dissociates cis-SNARE (Saccharomyces cerevisiae)


name: PLC-gamma 1 binds to p-EGFRvIII mutant (Homo sapiens)


name: Cdc6 protein is phosphorylated by CDK (Rattus norvegicus)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Schizosaccharomyces pombe)


name: an aliphatic alcohol + acetyl-CoA = an acetyl ester + CoA


name: dATP(out) + ADP(in) <=> dATP(in) + ADP(out)


name: 5-oxopentanoate + NADP(+) + H2O => glutarate + NADPH + 2 H(+)


name: p-IRF7 dimer interacts with coactivator CBP/p300 (Homo sapiens)


name: 4-hydroxy-L-proline(in) + Na(+)(in) = 4-hydroxy-L-proline(out) + Na(+)(out)


name: SOX17 and TFAP2C bind the TFAP2C gene (Homo sapiens)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Sus scrofa)


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Sus scrofa)


name: PKA/PKG phosphorylate Rap1GAP2 (Bos taurus)


name: esculetin + (2E)-geranyl diphosphate <=> 8-geranylesculetin + diphosphate


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol = (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone


name: lipopolysaccharide glucosyltransferase II activity


name: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 => ethene + L-dehydroascorbate + hydrogen cyanide + CO2 + 2 H2O


name: 2-(2-methylsulfanyl)ethylmalate = 2-(2-methylsulfanyl)ethylmaleate + H2O


name: 5'-deoxyinosine + phosphate = 5-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine


name: a (2E,4Z)-dienoyl-CoA + NADPH + H(+) = a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)


name: GAP binds to PDGF-beta receptors only (Homo sapiens)


name: beta-D-fructose 6-phosphate + ATP <=> beta-D-fructose 1,6-bisphosphate + ADP + H(+)


name: a phenyl acetate + H2O => a phenol + acetate + H(+)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)


name: Canonical WNT signaling through the atypical receptor RYK (Bos taurus)


name: (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + reduced [NADPH--hemoprotein reductase] + O2


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)


name: NT5C2 tetramer dephosphorylates RBV-MP (Mus musculus)


name: TFAP2A,TFAP2C homodimers stimulate ESR1 gene expression (Homo sapiens)


name: The polymerase component of DNA polymerase alpha:primase synthesizes a 20-nucleotide primer at the origin (Schizosaccharomyces pombe)


name: CA1:Zn2+,CA2:Zn2+ bind CA inhibitors (Sus scrofa)


name: (Z)-3-ureidoacrylate + H2O => (Z)-3-aminoacrylate + carbamate + H(+)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Rattus norvegicus)


name: TFAP2C homodimer binds MYC and KDM5B (Rattus norvegicus)


name: Transcytosis and dissociation of botB:NTNHA:HA (Homo sapiens)


name: Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (Bos taurus)


name: 12alpha,13alpha-dihydroxyfumitremorgin C + dimethylallyl diphosphate = fumitremorgin B + diphosphate


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Caenorhabditis elegans)


name: (8R)-hydroperoxy-(5Z,9E,11Z,14Z,17Z)-eicosapentaenoate => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2


name: Autoubiquitination of phospho-COP1(Ser-387 ) (Mus musculus)


name: luteolin 7-O-beta-D-glucoside + UDP + H(+) => luteolin + UDP-alpha-D-glucose


name: N-ethylsuccinimide + NAD(+) => N-ethylmaleimide + NADH + H(+)


name: ASC binds Caspase-8 complex (Bos taurus)


name: 6-hydroxymellein + (2E,6E)-farnesyl diphosphate <=> verruculide C + diphosphate


name: N-acetyl-L-glutamate 5-semialdehyde + L-glutamate => N(2)-acetyl-L-ornithine + 2-oxoglutarate


name: NEU3 cleaves GM3 to form LacCer (plasma membrane) (Mus musculus)


name: Retrograde vesicle is tethered at the ER by the NRZ complex and t-SNAREs (Gallus gallus)


name: (3R)-hydroxyhexacosanoyl-CoA <=> (2E)-hexacosenoyl-CoA + H2O


name: 27-hydroxycholesterol is 7alpha-hydroxylated (Canis familiaris)


name: O-phospho-L-threonine + H(+) <=> (R)-1-aminopropan-2-yl phosphate + CO2


name: narcotine hemiacetal + acetate + H(+) => 3-O-acetylpapaveroxine + H2O


name: (2Z,6E)-farnesyl diphosphate <=> (Z)-gamma-bisabolene + diphosphate


name: GUCYs converts GTP to cGMP (Drosophila melanogaster)


name: Cholesterol translocates from mitochondrial intermembrane space to inner mitochondrial membrane (Homo sapiens)


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Dictyostelium discoideum)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Mus musculus)


name: 3-hydroxypropanoyl-CoA = acryloyl-CoA + H2O


name: N-hexadecanoyl-(4R)-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + hexadecanoate


name: Phospho-R-Smad1/5/8 forms a complex with Co-Smad (Homo sapiens)


name: CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus (Bos taurus)


name: methylglyoxal + GMP = N(2)-(1-hydroxy-2-oxopropyl)-GMP


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Plasmodium falciparum)


name: methyl formate + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => alachlor + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: oroxylin A 7-O-beta-D-glucuronate + H2O <=> oroxylin A + D-glucuronate + H(+)


name: heptadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate <=> 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphate + CoA


name: activation of pyrimidine-containing compound salvage


name: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Homo sapiens)


name: D-arabinose 5-phosphate = D-ribulose 5-phosphate


name: VAV2 is a GEF for Rho/Rac family kinases (Bos taurus)


name: 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate => D-arabinose 5-phosphate + phosphoenolpyruvate + H2O


name: PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Canis familiaris)


name: RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters (Homo sapiens)


name: L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)


name: Receptor CXCR2 binds ligands CXCL1 to 7 (Gallus gallus)


name: 1-O-tetradecylglycerone 3-phosphate + hexadecanoate + H(+) => tetradecan-1-ol + 1-hexadecanoylglycerone 3-phosphate


name: 4xPALM-C-ABCA1 tetramer translocates from ER membrane to plasma membrane (Sus scrofa)


name: Keratin tetramers bind to form unit length filaments (Bos taurus)


name: ROCK phosphorylates LIMK1,2 (Homo sapiens)


name: TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome (Bos taurus)


name: Phosphorylation of LAT by p-SYK (Sus scrofa)


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Gallus gallus)


name: tetracosanoyl-CoA + AMP + diphosphate => tetracosanoate + ATP + CoA


name: TUSC3 transports Mg2+ from extracellular region to cytosol (Drosophila melanogaster)


name: glucose 6-phosphate + H2O => glucose + phosphate (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose => a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)


name: (2E)-tetracosenoyl-CoA + NADH + H(+) => tetracosanoyl-CoA + NAD(+)


name: Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin (Rattus norvegicus)


name: auxin efflux transmembrane transporter activity


name: 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+) => 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-L-ribitol


name: IMPDH tetramers binds IMPDH inhibitors (Saccharomyces cerevisiae)


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Mus musculus)


name: ATR phosphorylates Histone H2A.X at unsynapsed regions (Homo sapiens)


name: 3-methoxy-4-hydroxy-5-all-trans-hexaprenylbenzoate + S-adenosyl-L-homocysteine + H(+) => 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + S-adenosyl-L-methionine


name: D-glucose transmembrane transporter activity


name: glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)


name: L-arginyl-[protein] + S-adenosyl-L-methionine => N(5)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)


name: 3'-O-methyltricetin O methyl transferase activity


name: ADK phosphorylates RBV (Dictyostelium discoideum)


name: BACH1 translocates from the cytosol to the nucleoplasm (Mus musculus)


name: 3''-dehydroisoorientin => 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: (2E,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + NADPH + H(+) = (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + NADP(+)


name: (S)-3-amino-3-phenylpropanoate + pyruvate => 3-oxo-3-phenylpropanoate + L-alanine


name: oxalate(out) + sulfate(in) => oxalate(in) + sulfate(out)


name: a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + choline => a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + ethanolamine


name: cholate(out) + n H(+)(out) => cholate(in) + n H(+)(in)


name: ACBD4,5 bind MCFA-CoA and LCFA-CoA (Homo sapiens)


name: Phosphorylation of IRS (Rattus norvegicus)


name: LTA trimer binds TNFRSF1A,1B,14 (Mus musculus)


name: SFTPB dimer,C translocate from multivesicle body to lamellar body (Sus scrofa)


name: dADP(out) + ADP(in) => dADP(in) + ADP(out)


name: A REH hydrolses atREs to atROL and FAs (Homo sapiens)


name: 4-methyl-2-oxopentanoate + NADH + H(+) => (R)-2-hydroxy-4-methylpentanoate + NAD(+)


name: phosphoethanolamine + S-adenosyl-L-methionine = N-methylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)


name: oxalate(out) + chloride(in) => oxalate(in) + chloride(out)


name: Association between RAD9 and TopBP1 (Gallus gallus)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Canis familiaris)


name: neryl diphosphate + H2O <=> 1,8-cineole + diphosphate


name: PP2A dephosphorylates p-RHO to RHO (Mus musculus)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Danio rerio)


name: 2-butyloctyl sulfate + H2O = 2-butyloctan-1-ol + sulfate + H(+)


name: 8-oxo-dATP + H2O => 8-oxo-dAMP + diphosphate + H(+)


name: (Z)-1,2-dichloroethene + chloride + A + H(+) => trichloroethene + AH2


name: BLT receptors can bind LTB4 (Bos taurus)


name: PP2A demethylation by PPME1 (Mus musculus)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Mus musculus)


name: 2-hydroxydocosanoyl-CoA + sphinganine <=> N-(2-hydroxydocosanoyl)-sphinganine + CoA + H(+)


name: ferruginol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 => sugiol + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)


name: positive regulation of pentadecane metabolic process


name: a 3beta-hydroxysteroid + a triacylglycerol => a 3beta-hydroxysteroid ester + a diacylglycerol


name: Endocytosis of Ca impermeable AMPA receptors (Mus musculus)


name: eicosanoate + ATP + H(+) <=> icosanoyl-AMP + diphosphate


name: GRB2-1:SOS1 binds p-Y-SHC (Rattus norvegicus)


name: (2Z,6Z)-farnesyl diphosphate <=> (E)-alpha-bisabolene + diphosphate


name: nonanoyl-AMP + CoA <=> nonanoyl-CoA + AMP + H(+)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3B (GRIN3B) (Homo sapiens)


name: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde


name: Acyl Ghrelin and C-Ghrelin are secreted (Gallus gallus)


name: JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated (Homo sapiens)


name: pseudooxynicotine + 2 Fe(III)-[cytochrome c] + H2O <=> 4-oxo-4-(pyridin-3-yl)butanal + methylamine + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> (13E)-labda-7,13-dien-15-yl diphosphate


name: TRPV1 transports Ca2+ from extracellular region to cytosol (Canis familiaris)


name: Translocation of ERBB4s80 to the nucleus (Homo sapiens)


name: Abortive Initiation After Second Transition (Sus scrofa)


name: N(omega)-methyl-L-arginine + 2 NADH + 3 O2 + H(+) = N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + 2 NAD(+) + 3 H2O


name: HNF1B binds the DLL1 gene (Homo sapiens)


name: mycophenolate + UDP-alpha-D-glucuronate => mycophenolate 7-O-beta-D-glucuronide + UDP + H(+)


name: 1,4-diguanidinobutane + H2O <=> agmatine + urea


name: an N-acylsphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine => a 1-O-acyl-N-acylsphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine


name: 12-hydroxydodecanoate + NAD(+) <=> 12-oxododecanoate + NADH + H(+)


name: dehydrocitreoisocoumarin + holo-[ACP] + H2O => 3,5,7,9,11,13-hexaoxotetradecanoyl-[ACP]


name: (2E,6E)-farnesyl diphosphate = alpha-selinene + diphosphate


name: GLI3R binds the PTCH1 promoter (Homo sapiens)


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Mus musculus)


name: 4-(trimethylamino)butanoate + NADH + O2 + H(+) <=> trimethylamine + succinate semialdehyde + NAD(+) + H2O


name: O-phospho-L-serine + sulfite + H(+) = L-cysteate + phosphate


name: ESTG binds ESR1:chaperone complex (Drosophila melanogaster)


name: L-glutamate 5-semialdehyde + NADP(+) + H2O = L-glutamate + NADPH + 2 H(+)


name: HDACs deacetylate p-STAT3 dimers (Gallus gallus)


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+) => N-(8'-oxogeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2


name: adenine + H2O + H(+) = hypoxanthine + NH4(+)


name: SPHK2 binds SPHK2 inhibitors (Mus musculus)


name: Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Rattus norvegicus)


name: PLC-beta hydrolyses PIP2 to DAG and IP3 (Caenorhabditis elegans)


name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 (Canis familiaris)


name: cis-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O


name: EML4 recruits NUDC to mitotic spindle (Rattus norvegicus)


name: N(5)-[(S)-citryl]-D-ornithine + citrate + ATP = staphyloferrin A + AMP + diphosphate + H(+)


name: positive regulation of bilirubin UDP-glucuronosyltransferase activity


name: Defective pro-SFTPC does not translocate from ER membrane to multivesicle body (Homo sapiens)


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Danio rerio)


name: gibberellin A3 + S-adenosyl-L-methionine = O-methyl gibberellin A3 + S-adenosyl-L-homocysteine


name: hexanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: 3-oxooctacosanyol-CoA + NADPH + H(+) <=> (3R)-hydroxyoctacosanoyl-CoA + NADP(+)


name: hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + AMP + diphosphate => holo-[(hydroxy)phthioceranic acid synthase] + hexadecanoate + ATP


name: 3 menaquinol-8(in) + nitrite(out) + 2 H(+)(out) <=> 3 menaquinone-8(in) + NH4(+)(out) + 2 H2O(out)


name: caldopentamine + S-methyl-5'-thioadenosine + 2 H(+) => norspermine + S-adenosyl 3-(methylsulfanyl)propylamine


name: dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA (Rattus norvegicus)


name: Proteasome degrades polyubiquitinated PTEN (Xenopus tropicalis)


name: L-seryl-[protein] + butanoyl-CoA <=> O-butanoyl-L-seryl-[protein] + CoA


name: ZnT1 mediates the efflux of zinc from the cell (Mus musculus)


name: 2-acyl LPG is acylated to PG by CRLS1 (IM) (Saccharomyces cerevisiae)


name: hydroquinone + UDP-alpha-D-glucose <=> hydroquinone O-beta-D-glucopyranoside + UDP + H(+)


name: GPX2 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Mus musculus)


name: ATP1A:ATP1B:FXYD binds cardiac glycosides (Canis familiaris)


name: 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+) => 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol


name: Activation of p38 MAPK (Canis familiaris)


name: HEXB cleaves the terminal GalNAc from DS (Canis familiaris)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Plasmodium falciparum)


name: N-benzoylanthranilate + CoA => anthranilate + benzoyl-CoA


name: phomoidride A + 3 succinate + 3 CO2 + H2O => 2-[(1R,8S,14R,15R)-11-hydroxy-14,15-bis[(6E)-oct-6-en-1-yl]-3,5,9-trioxo-4,10-dioxatetracyclo[9.4.0.0(2,6).0(8,12)]pentadeca-2(6),12-dien-8-yl]acetate + 3 2-oxoglutarate + 3 O2


name: p-2S-SMAD2,3:SMAD4, p-2S-SMAD2,3:TRIM33, CTNNB1, EOMES, and TBPL2 bind FOXH1:SMAD3:GSC gene (Homo sapiens)


name: a 5'-end (5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenylyl)-adenylyl-cytidylyl-adenosine in mRNA + S-adenosyl-L-homocysteine


name: IL1F10 binds IL1RAPL1 (Canis familiaris)


name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Schizosaccharomyces pombe)


name: 3-nitropropanoate + NADP(+) => 3-nitroacrylate + NADPH + H(+)


name: CYP7B1 7-hydroxylates 25OH-CHOL (Xenopus tropicalis)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus (Danio rerio)


name: 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+) => 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine


name: 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+) => (E)-caffeate + O2


name: (2E,8Z,11Z,14Z,17Z,20Z,23Z)-hexacosaheptaenoyl-CoA + NADPH + H(+) => (8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADP(+)


name: a di-trans,poly-cis-polyprenol + NADPH + H(+) => a di-trans,poly-cis-dolichol + NADP(+)


name: rifampicin + NADPH + O2 => rifampicin para-naphthoquinone carboxamide + NADP(+) + H2O + H(+)


name: Receptor CXCR3 binds ligands CXCL9 to 11 (Canis familiaris)


name: SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)


name: (3R,6S)-6-hydroxy-3,7-dimethyloctanoate + H(+) => (4R,7S)-7-isopropyl-4-methyloxepan-2-one + H2O


name: positive regulation of macrophage inflammatory protein production


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Sus scrofa)


name: Fusion of COPII vesicle with Golgi complex (Homo sapiens)


name: Caspase mediated cleavage of BAP31 (Gallus gallus)


name: DVL is recruited to the receptor (Mus musculus)


name: Platelet-derived TREM-1 ligand binds to TREM-1 (Canis familiaris)


name: inhibition of adenylate cyclase activity by opioid receptor signaling pathway


name: p-CBL:GRB2 binds p-FRS2:activated FGFR3 (Rattus norvegicus)


name: 2-(L-cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile + reduced [NADPH--hemoprotein reductase] + O2 <=> (R)-dihydrocamalexate + hydrogen cyanide + oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)


name: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO2


name: 2-demethylmenaquinol-9 + S-adenosyl-L-methionine => menaquinol-9 + S-adenosyl-L-homocysteine + H(+)


name: dihydrobisanhydrobacterioruberin + A <=> bisanhydrobacterioruberin + AH2


name: CLIP1-LTK fusion autophosphorylates (Homo sapiens)


name: SOD1:Zn2+ apoenzyme binds CCS:Zn2+:2xCu1+ (Dictyostelium discoideum)


name: validamycin A + 2-oxoglutarate + O2 = validamycin B + succinate + CO2 + H(+)


name: 2-hydroxytetracosanoyl-CoA + sphinganine = N-(2-hydroxytetracosanoyl)-sphinganine + CoA + H(+)


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O => (N(2),N(2),N(7))-trimethyl-GMP + a 5'-end diphospho-ribonucleoside in mRNA + 2 H(+)


name: Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Bos taurus)


name: VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space (Homo sapiens)


name: monacolin J carboxylate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => monacolin L carboxylate + reduced [NADPH--hemoprotein reductase] + O2


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Danio rerio)


name: prostaglandin F2alpha + NADP(+) => 15-oxoprostaglandin F2alpha + NADPH + H(+)


name: G13 activation by TP receptor (Canis familiaris)


name: Fgr may phosphorylate p38 MAPK (Canis familiaris)


name: NFE2 binds the beta globin locus control region (Danio rerio)


name: ALOX15 oxidises 18(S)-HEPE to 18(S)-RvE3 (Danio rerio)


name: PhosphoChREBP (Thr 653) is exported to cytosol (Caenorhabditis elegans)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Rattus norvegicus)


name: 2-methyl-1,3,5-trinitrocyclohex-2-en-1-ide + NADP(+) => 4-methyl-1,3,5-trinitrocyclohexa-2,4-dien-1-ide + NADPH + H(+)


name: OTULIN,USP5 cleaves UBC yielding ubiquitin (Bos taurus)


name: DARPP-32 is dephosphorylated on Thr75 by PP2A (Sus scrofa)


name: a 7-hydroxyisoflavone + S-adenosyl-L-methionine = a 7-methoxyisoflavone + S-adenosyl-L-homocysteine + H(+)


name: Phosphorylation of NTAL by p-SYK/Lyn (Sus scrofa)


name: MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-tri-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 glycyl-tRNA(Gly) = MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-penta-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 tRNA(Gly) + 2 H(+)


name: vanadium ion transmembrane transporter activity


name: Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Danio rerio)


name: Full-length GD is cleaved by an unknown protease (Drosophila melanogaster)


name: Fc gamma receptors interact with antigen-bound IgG (Mus musculus)