name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Canis familiaris)


name: D-cystine(in) + ADP + phosphate + H(+) => D-cystine(out) + ATP + H2O


name: Start codon recognition (Schizosaccharomyces pombe)


name: PGR gene expression is stimulated by ERBB4s80:ESR1:estrogen (Homo sapiens)


name: a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine <=> an N(6)-methyl-2'-deoxyadenosine in DNA + S-adenosyl-L-homocysteine + H(+)


name: precorrin-1 + S-adenosyl-L-homocysteine + H(+) => uroporphyrinogen III + S-adenosyl-L-methionine


name: 3alpha-hydroxy-5alpha-androstane 17-O-(beta-D-glucuronate) + NADP(+) => 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + NADPH + H(+)


name: (2E)-geranyl diphosphate <=> isoterpinolene + diphosphate


name: calcium-dependent protein kinase activity


name: a 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+) => a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O


name: TRPV1 binds TRPV1 blockers (Drosophila melanogaster)


name: N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+) => N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Mus musculus)


name: dopamine + 2 L-ascorbate + O2 <=> (R)-noradrenaline + 2 monodehydro-L-ascorbate radical + H2O


name: Recruitment of CDK11p58 to the centrosomes (Sus scrofa)


name: MRE11 binds cytosolic DNA (Dictyostelium discoideum)


name: CCNG1 recruits PP2A-PPP2R5C to MDM2 (Xenopus tropicalis)


name: CD320-mediated TCN2:RCbl uptake and delivery to lysosome (Homo sapiens)


name: MeSeOH is reduced to MeSeH by TXNRD1 (Mus musculus)


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Homo sapiens)


name: an (E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amine + H2O + H(+) <=> an aliphatic amine + 2-dehydro-D-glucose


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Dictyostelium discoideum)


name: SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: HMOX1 dimer, HMOX2 cleave heme (Drosophila melanogaster)


name: spermine + O2 + H2O <=> 3-aminopropanal + spermidine + H2O2


name: (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+) => 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Gallus gallus)


name: HOXC8 binds CDH11 gene promoter (Homo sapiens)


name: pestalodiol + diphosphate => siccayne + dimethylallyl diphosphate


name: FA core complex:HSP70s binds PKR (Rattus norvegicus)


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Homo sapiens)


name: 20-hydroxy prostaglandin A1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => prostaglandin A1 + reduced [NADPH--hemoprotein reductase] + O2


name: VD3 translocates from extracellular region to ER membrane (Homo sapiens)


name: NQO1 interaction with ODC (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate => alpha-muurolene + diphosphate


name: propionyl-CoA + carnitine => propionylcarnitine + CoASH (Bos taurus)


name: YAP1 binds ZO-2 (TJP2) (Canis familiaris)


name: nicotinate beta-D-ribonucleotide + CO2 + diphosphate => quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+)


name: PCSK9 binds PCSK9 inhibitors (Xenopus tropicalis)


name: 2-methylpropanoyl-CoA + malonyl-[ACP] + H(+) = 4-methyl-3-oxopentanoyl-[ACP] + CO2 + CoA


name: L-leucine(out) + ATP + H2O => L-leucine(in) + ADP + phosphate + H(+)


name: The PIDDosome binds CASP2 (Homo sapiens)


name: N(6)-methyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine + H(+)


name: lipopolysaccharide glucosyltransferase I activity


name: 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + NADPH + O2 + H(+) = 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + NADP(+) + 2 H2O


name: RAS GAPs stimulate RAS GTPase activity (Rattus norvegicus)


name: acetyl-CoA + H2O => acetate + CoASH + H+ (Sus scrofa)


name: RHOB GAPs stimulate RHOB GTPase activity (Homo sapiens)


name: N-[(17Z)-hexacosenoyl]dihydrosphingosine + CoA + H(+) => (17Z)-hexacosenoyl-CoA + sphinganine


name: GDP + NAD(+) = N(2)-(ADP-D-ribosyl)-GDP + nicotinamide + H(+)


name: tryptamine + reduced [NADPH--hemoprotein reductase] + O2 = serotonin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Canis familiaris)


name: Heterodimerization of CEACAMs (Danio rerio)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the early endosome membrane (Mus musculus)


name: butan-1-ol + a quinone = butanal + a quinol


name: Cytoslic carboxylases translocate to mitochondrial matrix (Bos taurus)


name: a 2'-deoxyribonucleoside 5'-phosphate + ATP => a 2'-deoxyribonucleoside 5'-diphosphate + ADP


name: PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)


name: methylarsonous acid + S-adenosyl-L-methionine => dimethylarsinate + S-adenosyl-L-homocysteine + 2 H(+)


name: CTLA-4 binds B7-1/B7-2 (Canis familiaris)


name: Ubiquitination of stimulated EGFR (CBL) (Gallus gallus)


name: I(1,4,5)P3 transports from the ER lumen to the cytosol (Homo sapiens)


name: Duplex miRNA is loaded into Argonaute (Canis familiaris)


name: 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine => 4',7-dihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: WLS binds WNT ligands in the Golgi (Bos taurus)


name: SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Canis familiaris)


name: DNMT3A binds Me2sR4-HIST1H4 (Mus musculus)


name: DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Mus musculus)


name: 22-oxodocosanoate + NAD(+) + H2O = docosanedioate + NADH + 2 H(+)


name: LARG activation by G alpha 12/13 (Bos taurus)


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Bos taurus)


name: Endocytosis of TRAM (TICAM2) (Canis familiaris)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Gallus gallus)


name: PANK1/3 phosphorylate PanK (Mus musculus)


name: (1R,2R)-hydrobenzoin => cis-stilbene oxide + H2O


name: a ganglioside GD1b + H2O <=> a ganglioside GM1 + N-acetylneuraminate


name: SBF1 binds MTMR2 (Schizosaccharomyces pombe)


name: D-erythrose 4-phosphate + dihydroxyacetone phosphate => D-sedoheptulose 1,7-bisphosphate


name: 2-iminoacetate + H2O = glyoxylate + NH4(+)


name: Phosphorylation of cPLA2 by ERK-2 (Sus scrofa)


name: SMAD7 binds to SMURF2 (Canis familiaris)


name: Thr-180 of ULK1 is phosphorylated (Caenorhabditis elegans)


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+) => 1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + H2O


name: 1,6-dihydroxyphenazine + NADPH + O2 => 1,6-dihydroxyphenazine N(5)-oxide + NADP(+) + H2O


name: melibiose(in) + H(+)(in) = melibiose(out) + H(+)(out)


name: alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose = [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + UDP + H(+)


name: AWAT1 transfers acyl group from acyl-CoA to ARACOH, forming wax esters (Bos taurus)


name: cycloartenol + S-adenosyl-L-methionine = cyclolaudenol + S-adenosyl-L-homocysteine + H(+)


name: calcidiol + UDP-alpha-D-glucuronate <=> calcidiol 25-O-(beta-D-glucuronide) + UDP + H(+)


name: (E)-feruloylacetyl-CoA + (E)-feruloyl-CoA + H2O <=> curcumin + CO2 + 2 CoA


name: (2E)-butenoyl-CoA + H2O => 4-hydroxybutanoyl-CoA


name: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Mus musculus)


name: scyllo-inositol + NADP(+) => scyllo-inosose + NADPH + H(+)


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Dictyostelium discoideum)


name: Histone acetyltransferases are recruited to the TFF1 gene (Dictyostelium discoideum)


name: L-lysine + NADP(+) => L-1-piperideine-6-carboxylate + NH4(+) + NADPH + 2 H(+)


name: 3-oxo-(9Z-octadecenoyl)-CoA + CoA <=> (7Z)-hexadecenoyl-CoA + acetyl-CoA


name: type II restriction endodeoxyribonuclease inhibitor


name: PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins (Sus scrofa)


name: ALK mutants bind type I TKIs (Homo sapiens)


name: The high affinity receptor complex binds to G-protein (Sus scrofa)


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Xenopus tropicalis)


name: Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC (Canis familiaris)


name: (1R,4S)-menthone + NADPH + H(+) => (-)-menthol + NADP(+)


name: [4-(6-methylheptanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate + NADPH + H(+) => [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate + NADP(+)


name: positive regulation of interleukin-2-mediated signaling pathway


name: lactose 6-phosphate + H2O = D-galactose 6-phosphate + beta-D-glucose


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Homo sapiens)


name: an inositol-1-phosphophytoceramide + GDP-alpha-D-mannose => a mannosylinositol-1-phosphophytoceramide + GDP + H(+)


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine => 2 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Gallus gallus)


name: UNC119B stimulates translocation of myristoylated ciliary cargo to the primary cilium (Rattus norvegicus)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O <=> glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + a 1,2-diacylglycerol => an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a triacylglycerol


name: CARNS1 transforms ATP, L-His, b-Ala to CARN (Homo sapiens)


name: beta-D-4-deoxy-Delta(4)-GlcpA-(1->3)-beta-D-GlcpNAc + H2O => 5-dehydro-4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine


name: NAD-dependent protein demyristoylase activity


name: N(6)-tetradecanoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-tetradecanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: androsterone 3alpha-sulfate + adenosine 3',5'-bisphosphate + H(+) => androsterone + 3'-phosphoadenylyl sulfate


name: interleukin-14 receptor binding activity


name: D-mannonate + NAD(+) = D-mannuronate + NADH + H(+)


name: POMK 6-phosphorylates Mannose in GalNAc-GlcNAc-Man-DAG1 (Danio rerio)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DLAT (Drosophila melanogaster)


name: mTORC2 phosphorylates AKT1 on serine-473 (Schizosaccharomyces pombe)


name: (2E)-geranyl diphosphate <=> (-)-beta-phellandrene + diphosphate


name: Inactivation of APC/C via CDC20 sequestration (Xenopus tropicalis)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Self-ubiquitination of RNF41 (Homo sapiens)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Saccharomyces cerevisiae)


name: 1PYR-5COOH spontaneously hydrolyses to L-GluSS (Homo sapiens)


name: hexan-1-ol + NADP(+) => hexanal + NADPH + H(+)


name: HRH2 binds HRH2 antagonists (Drosophila melanogaster)


name: benzoate + NADH + O2 + H(+) = (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NAD(+)


name: beta-D-GalNAc-(1->4)-alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + H2O = alpha-L-IdoA-(1->3)-beta-D-GalNAc-4-sulfate-(1->4)-alpha-L-IdoA-(1->3)-D-GalNAc-4-sulfate + N-acetyl-D-galactosamine


name: The phagophore extends from the PIP3-enriched structure (Caenorhabditis elegans)


name: alpha-D-glucosamine 6-phosphate + H2O <=> beta-D-fructose 6-phosphate + NH4(+)


name: Hydrolysis of choloyl-CoA to cholate and CoASH (Sus scrofa)


name: 4-chlorophenylacetate + NADH + O2 => 3,4-dihydroxyphenylacetate + chloride + NAD(+)


name: Neuromedin-U receptors bind neuromedins U, S (Sus scrofa)


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Rattus norvegicus)


name: (S)-cis-N-methylstylopine + S-adenosyl-L-homocysteine => (S)-stylopine + S-adenosyl-L-methionine


name: benzylthiol + O2 = benzothialdehyde + H2O2


name: MYLIP dimer ubiquitinates VLDLR on Lys-839 (Canis familiaris)


name: glycine betaine + [thioredoxin]-dithiol + phosphate + H(+) => acetyl phosphate + trimethylamine + [thioredoxin]-disulfide + H2O


name: biosynthesis of lactosylceramide precursor to globoside


name: PIAS4 SUMOylates HERC2 with SUMO1 (Rattus norvegicus)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Sus scrofa)


name: Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Rattus norvegicus)


name: (R)-4'-phosphopantothenate + L-cysteine + CTP => N-[(R)-4-phosphopantothenoyl]-L-cysteine + CMP + diphosphate + H(+)


name: Translocation of STAT1 dimer to nucleus (Mus musculus)


name: 6-deoxoteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 3-dehydro-6-deoxoteasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: 4-aminobutanoate + O2 + H2O <=> succinate semialdehyde + H2O2 + NH4(+)


name: FABPs bind LCFAs (Caenorhabditis elegans)


name: Interaction of PAK1 with Rac1-GTP (Rattus norvegicus)


name: 1-deoxysphinganine + NADP(+) <=> 1-deoxy-3-dehydrosphinganine + NADPH + H(+)


name: (R)-2-benzylsuccinate + succinyl-CoA => (R)-2-benzylsuccinyl-CoA + succinate


name: RNASEs bind bacterial LPS, PGN (Bos taurus)


name: Factor H binds to membrane-associated C3b (Danio rerio)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho]-glycerol + CoA


name: [protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine


name: cytidine(34) in tRNA(Ile2) + L-lysine + ATP <=> lysidine(34) in tRNA(Ile2) + AMP + diphosphate + H(+)


name: alpha-D-ribose 1-methylphosphonate 5-phosphate + AH2 + S-adenosyl-L-methionine <=> alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane + 5'-deoxyadenosine + L-methionine + A + H(+)


name: Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)


name: a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: 4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate + H(+)


name: 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase activity


name: 4-amino-2,6-dinitrotoluene + UDP-alpha-D-glucose => 4-amino-2,6-dinitrotoluene beta-D-glucoside + UDP + H(+)


name: Recruitment of p190RhoGEF to p-FAK (Rattus norvegicus)


name: MLKL binds HSP90:CDC37 (Xenopus tropicalis)


name: fumarate(in) + succinate(out) <=> fumarate(out) + succinate(in)


name: GOT2 dimer transaminates L-Asp (Homo sapiens)


name: RNF146 polyubiquitinates PARylated PTEN (Canis familiaris)


name: 3-phenylpropylamine + pyruvate => 3-phenylpropanal + L-alanine


name: L-anticapsin + L-alanine + ATP => bacilysin + ADP + phosphate + H(+)


name: beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + UDP-alpha-D-galactose <=> a neolactoside nLc4Cer + UDP + H(+)


name: aurachin C epoxide + NAD(+) + H2O => aurachin C + NADH + O2 + H(+)


name: L-dihomomethionine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-5-(methylsulfanyl)pentanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)


name: UCHL3, SENP8 cleave NEDD8 (Xenopus tropicalis)


name: cyclohexane-1-carboxylate + butanoyl-CoA = cyclohexane-1-carbonyl-CoA + butanoate


name: PYGM b dimer:AMP complex <=> PYGM dimer, b form + 2 AMP (Dictyostelium discoideum)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + GDP-alpha-D-mannose = a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP + H(+)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Rattus norvegicus)


name: positive regulation of penicillin biosynthetic process


name: p-PKR dimer phosphorylates CDK1 (Sus scrofa)


name: (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + CoA => (2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + octanoyl-CoA


name: ATG10 transfers ATG12 from ATG7 to ATG10 (Homo sapiens)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + malonyl-CoA + H(+) => 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA


name: Formation of TSC1:TSC2 complex (Bos taurus)


name: Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Canis familiaris)


name: 9-cis-retinol + NADP(+) = 9-cis-retinal + NADPH + H(+)


name: myricetin 3-O-[(6-O-(E)-caffeoyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] + CoA => myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + (E)-caffeoyl-CoA


name: WLS is endocytosed to the early endosome (Canis familiaris)


name: ADRM1:26S proteaseome binds UCHL5 (Schizosaccharomyces pombe)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate (Bos taurus)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Drosophila melanogaster)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Saccharomyces cerevisiae)


name: 3 ATP <=> 5'-triphosphoadenylyl-(2'->5')-adenylyl-(2'->5')-adenosine + 2 diphosphate


name: CYP21A2 oxidises 17HPROG (Dictyostelium discoideum)


name: E2F6 binds APAF1 gene promoter (Homo sapiens)


name: Activation of proMMP11 by FURIN (Gallus gallus)


name: dihydroniloticin + 2 oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+) => tirucalla-7,24-dien-3beta-ol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2


name: (9Z,12Z)-octadecadienoate + O2 = (9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: L-ornithine + pyruvate + NADPH + H(+) => N(5)-[1(S)-1-carboxyethyl]-L-ornithine + NADP(+) + H2O


name: a (2R)-2-methylacyl-CoA => a (2S)-2-methylacyl-CoA


name: plastoquinone-9 + 15,9'-di-cis-phytofluene = plastoquinol-9 + 9,9',15-tri-cis-zeta-carotene


name: p-CBL:GRB2 binds p-FRS2:activated FGFR4 (Drosophila melanogaster)


name: ATG3 transfers LC3 from ATG7 to ATG3 (Mus musculus)


name: negative regulation of anti-Mullerian hormone signaling pathway


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Plasmodium falciparum)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Danio rerio)


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Drosophila melanogaster)


name: vitexin + UDP-alpha-D-glucose => vitexin 2''-O-beta-D-glucoside + UDP + H(+)


name: MITF-M-dependent IRF4 gene expression (Homo sapiens)


name: NEIL1,NEIL2 incises DNA strand 5' to the AP site (Bos taurus)


name: site-specific DNA-methyltransferase (adenine-specific) activity


name: positive regulation of electron transfer flavoprotein, group I


name: acetoacetyl-CoA + L-isoleucine + ATP = tenuazonic acid + AMP + diphosphate + CoA + 2 H(+)


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Rattus norvegicus)


name: Beta-catenin migrates to the nucleus (Danio rerio)


name: pantothenate biosynthesis from 2-oxypantoyl lactone


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Saccharomyces cerevisiae)


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Canis familiaris)


name: Synthesis of antigenomic RNA of human respiratory syncytial virus (Homo sapiens)


name: (S)-3-hydroxy-2-methylpropanoate + NAD(+) = (S)-2-methyl-3-oxopropanoate + NADH + H(+)


name: 1D-myo-inositol 3-phosphate + CTP + H(+) <=> CDP-1L-myo-inositol + diphosphate


name: negative regulation of protein-glutamine gamma-glutamyltransferase activity


name: IRF3 is phosphorylated by TBK1 (Bos taurus)


name: 4-hydroxybenzoate + NADPH + O2 + 2 H(+) = hydroquinone + CO2 + NADP(+) + H2O


name: Mcm2-7 is phosphorylated by DDK (Homo sapiens)


name: Release of Cytochrome c from mitochondria (Canis familiaris)


name: PGM1:Mg2+ isomerises G6P to G1P (Drosophila melanogaster)


name: POLI simultaneously binds REV1 and monoUb:K164-PCNA at damaged DNA (Rattus norvegicus)


name: Acetyl Aldehyde Dehydrogenase Inhibitors


name: epi-neemfruitin B + acetyl-CoA => 7-acetyl-epi-neemfruitin B + CoA


name: N(2)-acetyl-L-citrulline + H2O <=> L-citrulline + acetate


name: L-serine + NAD(+) + H2O <=> 3-hydroxypyruvate + NH4(+) + NADH + H(+)


name: KMT2A (MLL) binds RUNX1 (Drosophila melanogaster)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)


name: DICER1 hydrolyzes maternal mRNA:lncRNA to yield endosiRNA (Homo sapiens)


name: SH2 domain of Src binds to the active receptor (Gallus gallus)


name: Polyubiquitinated NRIF binds to p62 (Sequestosome) (Gallus gallus)


name: octan-1-ol + 2 Fe(III)-[cytochrome c] = octanal + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: gamma-secretase cleaves the p75NTR transmembrane domain (Danio rerio)


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Sus scrofa)


name: Phosphorylated SHC1 in complex with p-5Y-EGFRvIII recruits GRB2:SOS1 complex (Homo sapiens)


name: D-cellobiono-1,5-lactone + H2O <=> 4-O-beta-D-glucopyranosyl-D-gluconate + H(+)


name: M2 receptor signaling pathway involved in heart process


name: PIAS4 SUMOylates VDR with SUMO2 (Drosophila melanogaster)


name: an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate <=> an alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + 2-oxoglutarate + O2 = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + formaldehyde + succinate + CO2


name: CoA-glutathione + NADPH + H(+) => glutathione + NADP(+) + CoA


name: Interaction of PECAM-1 and PLC gamma1 (Bos taurus)


name: P2X7 mediates membrane pores that include pannexin-1 (Gallus gallus)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O => 1,3-dihexadecanoylglycerol + (9Z)-octadecenoate + H(+)


name: 1D-chiro-inositol(out) + 2 Na(+)(out) = 1D-chiro-inositol(in) + 2 Na(+)(in)


name: activation of tyrosine phosphorylation of Stat3 protein


name: Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane (Gallus gallus)


name: Conversion of glyoxylate to oxalate (Caenorhabditis elegans)


name: naphthalene-1,3,6,8-tetrol + NADPH + H(+) => scytalone + NADP(+)


name: glutathione disulfide oxidoreductase activity


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Homo sapiens)


name: [N-(2,3-dihydroxybenzoyl)-L-seryl]2-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine + H(+) => monoglucosyl-enterobactin + H2O


name: G-protein alpha subunit is inactivated (Canis familiaris)


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Canis familiaris)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Dictyostelium discoideum)


name: antimonite secondary active transmembrane transporter activity


name: HMOX1 dimer, HMOX2 cleave heme (Homo sapiens)


name: N,N-dimethylglycine + S-adenosyl-L-homocysteine + H(+) => sarcosine + S-adenosyl-L-methionine


name: NADSYN1 hexamer amidates NAAD to NAD+ (Schizosaccharomyces pombe)


name: PTPN11 dephosphorylates RUNX1 (Gallus gallus)


name: 7-dehydrocholesterol + A + H2O <=> cholesta-5,7-dien-3beta,25-diol + AH2


name: 2-dehydro-D-glucose = cortalcerone + H2O


name: XPO1 (CRM1) binds to BACH1:Hemes (Rattus norvegicus)


name: a 5,6-dihydrouridine in mRNA + NADP(+) <=> a uridine in mRNA + NADPH + H(+)


name: Excess homocysteine yields homolanthionine and H2S (Saccharomyces cerevisiae)


name: CASP9 is phosphorylated at T412 (Rattus norvegicus)


name: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized 2[4Fe-4S]-[ferredoxin] = 6-hydroxynicotinate + reduced 2[4Fe-4S]-[ferredoxin] + 2 H(+)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Drosophila melanogaster)


name: LRP2 binds extracellular TCN2:RCbl (Homo sapiens)


name: WICH phosphorylates H2AFX on Y142 (Rattus norvegicus)


name: methionyl-initiator methionine tRNA binding


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Rattus norvegicus)


name: thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H(+)


name: ABHD6,12 hydrolyse 3AG (Drosophila melanogaster)


name: 2 2-iminio-3-(indol-3-yl)propanoate + H2O2 => indole-3-pyruvate imine dimer + 2 H2O


name: ALPI dimer hydrolyses phosphate monoesters (Xenopus tropicalis)


name: a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> a 1-[(6Z,9Z,12Z,15Z)-octadectetraenoyl]-2-acyl-glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: precorrin-5 + S-adenosyl-L-methionine + H2O <=> precorrin-6A + acetate + S-adenosyl-L-homocysteine + 2 H(+)


name: 3',5'-cyclic AMP(in) + a dicarboxylate(out) => 3',5'-cyclic AMP(out) + a dicarboxylate(in)


name: Tyrosine is monoiodinated (Caenorhabditis elegans)


name: UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + ADP + phosphate + H(+) => UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + L-lysine + ATP


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Sus scrofa)


name: glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + UDP + H(+)


name: ubiquinone-10 + NADH + H(+) = ubiquinol-10 + NAD(+)


name: 11-oxomiltiradiene + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+) => miltiradiene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2


name: a 1-acyl-sn-glycero-3-phosphate + NADP(+) => a 1-acylglycerone 3-phosphate + NADPH + H(+)


name: voriconazole(out) + ADP + phosphate + H(+) => voriconazole(in) + ATP + H2O


name: (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde => prostaglandin H2


name: PEX19:class I PMP binds PEX3 (Dictyostelium discoideum)


name: wogonin + D-glucuronate + H(+) => wogonin 7-O-beta-D-glucuronate + H2O


name: kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Homo sapiens)


name: DENND1s exchange GTP for GDP on RAB35 (Homo sapiens)


name: PKC alpha interacts with and phosphorylates KIT (Gallus gallus)


name: Autocatalytic activation of MMP7 (Canis familiaris)


name: SIRT3 deacetylates AcK-IDH2 dimer (Mus musculus)


name: biphenyl-2,2',3-triol + NAD(+) => dibenzofuran + NADH + O2 + H(+)


name: tetradecanoyl-CoA + glycine <=> N-tetradecanoylglycine + CoA + H(+)


name: MAPK1-dependent phosphorylation of MITF-M (Rattus norvegicus)


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Homo sapiens)


name: phytol + dodecanoyl-CoA = dodecanoate phytyl ester + CoA


name: (2E,10E)-dode-2,10-dicenoyl-CoA + oxaloacetate + H(+) => [4-(deca-1,8-diyl)-2,5-dioxo-2,5-dihydro-3-furanyl]acetate + CoA + H2O


name: WWTR1 (TAZ) binds TEAD (Xenopus tropicalis)


name: trimethylamine N-oxide + a menaquinol + H(+) => trimethylamine + a menaquinone + H2O


name: Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)


name: an aliphatic alcohol + a fatty acid + H(+) => a fatty acid ester + H2O


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Rattus norvegicus)


name: guanosine(2270) in 21S rRNA + S-adenosyl-L-methionine => 2'-O-methylguanosine(2270) in 21S rRNA + S-adenosyl-L-homocysteine + H(+)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Rattus norvegicus)


name: UBA1 adenylates ubiquitin in the nucleoplasm (Sus scrofa)


name: NRXNs bind NLGNs (Caenorhabditis elegans)


name: sphing-4-enine-phosphocholine + H2O => sphing-4-enine 1-phosphate + choline + H(+)


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Canis familiaris)


name: 28-norteasterone + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+) => 6-deoxo-28-norteasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Rattus norvegicus)


name: D-malate dehydrogenase (decarboxylating) (NAD+) activity


name: GBF1 stimulates ARF nucleotide exchange (Gallus gallus)


name: SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Rattus norvegicus)


name: CDP-choline + diphosphate => phosphocholine + CTP + H(+)


name: OGDH dimer decarboxylates 2-OG (Dictyostelium discoideum)


name: hexadecanoyl-CoA + NADH + H(+) => hexadecanal + NAD(+) + CoA


name: glutathione(out) + 3 Na(+)(out) = glutathione(in) + 3 Na(+)(in)


name: Phosphorylation of WWTR1 (TAZ) by LATS2 (Canis familiaris)


name: eburicol + reduced [NADPH--hemoprotein reductase] + O2 = 32-hydroxyeburicol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: SUMOylation of TOPORS with SUMO1 (Rattus norvegicus)


name: Metabotropic glutamate receptors bind glutamate (Canis familiaris)


name: (2E)-decenoate + holo-[ACP] + ATP <=> (2E)-decenoyl-[ACP] + AMP + diphosphate


name: 1-octadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O = pentanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: HLCS biotinylates ACACB (Plasmodium falciparum)


name: a 2-oxocarboxylate + AH2 => a (2R)-2-hydroxycarboxylate + A


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Xenopus tropicalis)


name: tandutinib-resistant FLT3 mutants don't bind tandutinib (Homo sapiens)


name: p-Y705-STAT3:p-Y693-STAT4 translocates to the nucleus (Canis familiaris)


name: p-T68-CHEK2 dimerizes (Saccharomyces cerevisiae)


name: ethyl acetate + CoA => ethanol + acetyl-CoA


name: Activated FGFR3:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: ALDH3A2-1 oxidises HD2NAL to PALM (Danio rerio)


name: (2E,6E)-farnesyl diphosphate + H2O = koraiol + diphosphate


name: tardioxopiperazine A + dimethylallyl diphosphate => variecolorin L + diphosphate


name: Cytoslic carboxylases translocate to mitochondrial matrix (Caenorhabditis elegans)


name: CAND1 binds cytosolic CRL E3 ubiquitin ligases (Xenopus tropicalis)


name: inositol tetrakisphosphate 3-kinase activity


name: ARV1 transports CHOL from ER membrane to plasma membrane (Bos taurus)


name: MAPKAPK2 phosphorylates CREB at Serine 133 (Drosophila melanogaster)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Sus scrofa)


name: L-methionine sulfone + acetyl-CoA <=> N-acetyl-L-methionine sulfone + CoA + H(+)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 => (5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: Activated FGFR1 phosphorylates FRS3 (Rattus norvegicus)


name: Aldolase tetramers convert GA3P and DHAP to F1,6PP (Xenopus tropicalis)


name: oxidized 2[4Fe-4S]-[ferredoxin] + oxalate = reduced 2[4Fe-4S]-[ferredoxin] + 2 CO2


name: OTUD7B,TNFAIP3 deubiquitinate TRAF6 (Canis familiaris)


name: 2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+) => uridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP


name: Association of procollagen type XIII (Rattus norvegicus)


name: thymidine 2-oxoglutarate dioxygenase activity


name: phenazine-1-carboxylate + S-adenosyl-L-methionine => 5-methyl-phenazine-1-carboxylate + S-adenosyl-L-homocysteine


name: PDCL binds G-protein beta and TRiC/CCT (Homo sapiens)


name: ZNRF3 autoubiquitinates to promote its internalization (Bos taurus)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: SLC29A1,2 transport 6MP from extracellular region to cytosol (Mus musculus)


name: Phosphorylation of ITAM motifs in CD3 complexes (Bos taurus)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Bos taurus)


name: NUDT1 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Plasmodium falciparum)


name: D-ornithine(in) + L-ornithine(out) = D-ornithine(out) + L-ornithine(in)


name: (2E,6E)-farnesyl diphosphate = (-)-7-epi-alpha-selinene + diphosphate


name: (S)-3-hydroxy-2-methylpropanoate + NAD(+) <=> (S)-2-methyl-3-oxopropanoate + NADH + H(+)


name: Formation of CDK4/6:CCND complexes (Danio rerio)


name: Unknown kinase phosphorylates CLEC1B dimer:PDPN (Homo sapiens)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) (Rattus norvegicus)


name: Persulfide sulfur is dioxygenated (Caenorhabditis elegans)


name: USP7 deubiquitinates TP53,MDM2,MDM4,FOXO4, PTEN (Dictyostelium discoideum)


name: LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Xenopus tropicalis)


name: Activated JNKs phosphorylate c-JUN (Rattus norvegicus)


name: L-serine transmembrane transporter activity


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Homo sapiens)


name: Phosphorylated SHC1 recruits SHIP (Canis familiaris)


name: bis(2-hydroxyethyl) terephthalate + H2O = 4-[(2-hydroxyethoxy)carbonyl]benzoate + ethylene glycol + H(+)


name: (6E)-nerolidol + diphosphate => (2Z,6E)-farnesyl diphosphate + H2O


name: "Thioether and trialkylsulfonium hydrolases"


name: 2-methyl-2-(methylamino)propanoate(in) + chloride(in) + 2 Na(+)(in) => 2-methyl-2-(methylamino)propanoate(out) + chloride(out) + 2 Na(+)(out)


name: docosanoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in) => docosanoate(out) + ATP(in) + CoA(in) + H(+)(out)


name: p-S256-Aquaporin-2 passively transports water into cell (Plasmodium falciparum)


name: (S)-1-pyrroline-5-carboxylate + NAD(+) + 2 H2O <=> L-glutamate + NADH + H(+)


name: CDP-D-glucitol + NADP(+) <=> CDP-6-keto-D-fructose + NADPH + H(+)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + O2 = 2-[12-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoyl]-glycerol


name: (1S,5R)-carveol + NADP(+) => (R)-carvone + NADPH + H(+)


name: Ubiquitination of DLL/JAG ligands upon binding to NOTCH2 (Homo sapiens)


name: JMJD1C demethylates H3K9 mono- and di-methylation (Drosophila melanogaster)


name: Phosphorylation of STAT1 by JAK kinases (Danio rerio)


name: ABCC4 transports TPMP substrates from cytosol to extracellular region (Dictyostelium discoideum)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate = 9-(9Z-octadecenoyloxy)-octadecanoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol


name: (2E,6E)-farnesyl diphosphate <=> 5-epi-alpha-selinene + diphosphate


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA => (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + H2O


name: C-C motif chemokine 21 receptor activity


name: DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function (Mus musculus)


name: Receptor FFAR2 binds carboxylates (Bos taurus)


name: 6beta-hydroxycortisone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => cortisone + reduced [NADPH--hemoprotein reductase] + O2


name: acetoacetyl-CoA + succinate => acetoacetate + succinyl-CoA


name: ADAM10:Zn2+:TSPANs translocates from ER lumen to plasma membrane (Homo sapiens)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Sus scrofa)


name: 1,3-di-(9Z)-octadecenoyl-2-hexadecanoylglycerol + H2O => 2-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)


name: 3',4',7-trihydroxyflavone + S-adenosyl-L-methionine = 4',7-dihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-O-hexadecyl-sn-glycero-3-phosphocholine + H2O <=> 2-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)


name: P4HB binds Collagen chains (Danio rerio)


name: prolactin-releasing peptide receptor binding


name: eburicol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 <=> 14-demethyleburicol + formate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Schizosaccharomyces pombe)


name: negative regulation of ATP biosynthetic process


name: CFTR transports Cl- from cytosol to extracellular region (Sus scrofa)


name: Interleukin-23 binds interleukin-23 receptor (Canis familiaris)


name: a 2-oxocarboxylate + L-alanine <=> an L-alpha-amino acid + pyruvate


name: MAP kinase serine/threonine phosphatase activity


name: activation of nitric oxide metabolic process


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Sus scrofa)


name: SPAST (spastin) binds the IST1 subunit of ESCRT-III at the sites of microtubule attachment to chromatin (Rattus norvegicus)


name: 1-nonadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine = 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: a hydroperoxide + [protein]-dithiol <=> [protein]-disulfide + an alcohol + H2O


name: Cob(I)alamin bound to MMACHC is oxidized to cob(II)alamin (Homo sapiens)


name: PSMD5 and PSMD2 bind PSMC2:PSMC1 (Homo sapiens)


name: Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)


name: tardioxopiperazine A + dimethylallyl diphosphate <=> variecolorin L + diphosphate


name: a hydroxy-epoxy-eicosatetraenoate => a hydroperoxyeicosatetraenoate


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Sus scrofa)


name: Defective NEIL1 variants do not cleave Tg (Homo sapiens)


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Xenopus tropicalis)


name: kanamycin A + carbamoyl phosphate + ATP + H2O <=> 6''-O-carbamoylkanamycin A + AMP + phosphate + diphosphate + H(+)


name: digoxigenin + 2 Fe(II)-[cytochrome c] + 3 H(+) => dihydrodigoxigenin + 2 Fe(III)-[cytochrome c]


name: p-CD19:VAV binds PI3K and GRB2 (Canis familiaris)


name: HRH1 binds HRH1 inverse agonists (Sus scrofa)


name: uridine(34) in tRNA + AH2 + O2 = 5-hydroxyuridine(34) in tRNA + A + H2O


name: SUMOylation of ING2 with SUMO1 (Xenopus tropicalis)


name: 3'-incision of DNA by ERCC5 (XPG) in GG-NER (Homo sapiens)


name: methyl beta-D-galactoside(out) + ATP + H2O = methyl beta-D-galactoside(in) + ADP + phosphate + H(+)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Danio rerio)


name: Heterodimerization of nephrin and KIRREL2, KIRREL3 (Drosophila melanogaster)


name: MME:Zn2+ binds sacubitrilat (Mus musculus)


name: 2 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycero-3-phosphoethanolamine


name: (9Z,11E)-octadecadienoate + H2O => 10-hydroxy-(11E)-octadecenoate


name: Phosphorylated MAPKs translocate into the nucleus (Homo sapiens)


name: N(6)-methyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine <=> N(6),N(6)-dimethyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine + H(+)


name: 1-hexadecanoylglycerol + H2O = glycerol + hexadecanoate + H(+)


name: a C2-C8-saturated long-chain fatty acyl-[ACP] + 2 reduced [flavodoxin] + 3 O2 <=> 6-carboxyhexanoyl-[ACP] + a fatty aldehyde + 2 oxidized [flavodoxin] + 3 H2O + 3 H(+)


name: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA


name: 2-(methylaminoethyl)phosphonate + O2 + H2O = phosphonoacetaldehyde + methylamine + H2O2


name: 2 N-(3-carboxypropanoyl)-N-hydroxycadaverine + 2 ATP = bisucaberin + 2 AMP + 2 diphosphate + 2 H(+)


name: CD28 homodimer binds B7-2 monomer (Rattus norvegicus)


name: selenite(out) + ATP + H2O <=> selenite(in) + ADP + phosphate + H(+)


name: heme b + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = biliverdin IXalpha + CO + Fe(2+) + 3 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+)


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) => 3-(3,4-dihydroxyphenyl)pyruvate + NADH + H(+)


name: Rag dimer formation (Xenopus tropicalis)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 => N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-glycine


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Danio rerio)


name: LMF1,2 transport LIPC dimer from ER lumen to extracellular region (Rattus norvegicus)


name: fumarate(out) + 2 H(+)(out) => fumarate(in) + 2 H(+)(in)


name: L-proline + 2-oxoglutarate + O2 => cis-3-hydroxy-L-proline + succinate + CO2


name: dihydroxyacetone + D-glyceraldehyde 3-phosphate => D-xylulose 5-phosphate + formaldehyde


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Rattus norvegicus)


name: CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Sus scrofa)


name: DELE1(143-515) binds EIF2AK1 (HRI) (Mus musculus)


name: Autophosphorylation of PDGF alpha/beta receptors (Caenorhabditis elegans)


name: pyridoxine 5'-phosphate + H2O => pyridoxine + phosphate


name: N-acetyl-L-glutamate + ATP = N-acetyl-L-glutamyl 5-phosphate + ADP


name: FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)


name: ING2 binds PI5P (Drosophila melanogaster)


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + O2 + H2O <=> (1-deoxy-D-fructos-1-yl)amine + an aldehyde + H2O2


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Dictyostelium discoideum)


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Danio rerio)


name: ICMT:Zn2+ transfers CH3 from AdoMet to isoprenylated proteins (Drosophila melanogaster)


name: 4-hydroxybenzaldehyde + acetyl-CoA => (E)-4-coumaroyl-CoA + H2O


name: (S)-2,3-diaminopropanoate + 2-oxoglutarate + NADH + H(+) => N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD(+) + H2O


name: 8-oxo-dATP + H2O <=> 8-oxo-dAMP + diphosphate + H(+)


name: ADP-alpha-D-glucose + D-glucose = alpha,alpha-trehalose + ADP + H(+)


name: ATP7A transports cytosolic Cu2+ to phagosomal lumen (Homo sapiens)


name: Formation of Cyclin E:Cdk2 complexes (Sus scrofa)


name: ferric-chelate reductase (NADPH) activity


name: BBSome binds RAB3IP (Xenopus tropicalis)


name: ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Gallus gallus)


name: diethylphosphate + 4-nitrophenol + 2 H(+) => paraoxon + H2O


name: SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Canis familiaris)


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Gallus gallus)


name: phycocyanobilin-L-cysteinyl(84)-[allophycocyanin beta-subunit] <=> apo-L-cysteinyl(84)-[allophycocyanin beta-subunit] + (2R,3E)-phycocyanobilin


name: doxorubicin(in) + H(+)(out) = doxorubicin(out) + H(+)(in)


name: riboflavin + H2O + H(+) => lumichrome + ribitol


name: L-cysteate + H2O <=> sulfite + pyruvate + NH4(+) + H(+)


name: Displacement of UNG glycosylase by APEX1 at the AP site (Xenopus tropicalis)


name: mitochondrial electron transport, succinate to ubiquinone


name: an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O <=> 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)


name: N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2,3) + H2O => N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + beta-D-mannose


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Gallus gallus)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Saccharomyces cerevisiae)


name: Exocytosis of secretory granule membrane proteins (Plasmodium falciparum)


name: 1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid = a 1-acylglycerone 3-phosphate + hexadecanoate


name: 3,8,9,10-tetrahydroxy-6-methyl-1,4-dihydroanthracen-1-one + NADPH + H(+) <=> (3R)-3,8,9,10-tetrahydroxy-6-methyl-1,2,3,4-tetrahydroanthracen-1-one + NADP(+)


name: B3GAT3 dimer transfers GlcA to tetrasaccharide linker (Sus scrofa)


name: 16alpha,17alpha-estriol + UDP-alpha-D-glucuronate = 16alpha,17alpha-estriol 17-O-(beta-D-glucuronate) + UDP + H(+)


name: 3,3',5-triiodo-L-thyronine + 3'-phosphoadenylyl sulfate = 3,3',5-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: spermine + O2 + H2O = spermine monoaldehyde + H2O2 + NH4(+)


name: N-acyl-15-methylhexadecasphing-4-enine-1-phosphate + H2O => an N-acyl-15-methylhexadecasphing-4-enine + phosphate


name: L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose = alpha-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H(+)


name: Active IKBKB phosphorylates NF-kappa-B inhibitor  (Rattus norvegicus)


name: Chenodeoxycholoyl CoA reacts with glycine or taurine to form glycochenodeoxycholate or taurochenodeoxycholate (Canis familiaris)


name: a fatty acyl-CoA + (R)-carnitine => a fatty acyl-L-carnitine + CoA


name: N-hexadecanoylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+) => N-hexadecanoyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O


name: 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA => 3-(methylsulfanyl)acryloyl-CoA + H2O


name: methyl 2-[(3S)-9,10-dihydroxy-7-methoxy-1-oxo-1H,3H,4H-naphtho[2,3-c]pyran-3-yl]acetate + AH2 <=> semiviriditoxin + A


name: docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 2 (S)-methylmalonyl-CoA + 3 malonyl-CoA + 5 NADPH + 10 H(+) => C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 NADP(+) + 5 CoA + 2 H2O


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Xenopus tropicalis)


name: E2F6 forms the PRC1L4 complex (Bos taurus)


name: PAK1-3 dimer disassociates (Drosophila melanogaster)


name: a quinol + NADP(+) => a quinone + NADPH + H(+)


name: ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol (Homo sapiens)


name: quillate + UDP-alpha-D-glucose <=> quillaic acid 28-beta-D-glucoside + UDP


name: 3-oxo-(13Z)-eicosenoyl-CoA + CO2 + CoA => (11Z)-octadecenoyl-CoA + malonyl-CoA + H(+)


name: Recruitment of BCAR1 to PTK2 complex (Sus scrofa)


name: activation of nickel superoxide oxidoreductase


name: 5alpha-androstane-3alpha,17beta-diol + NAD(+) => 17beta-hydroxy-5alpha-androstan-3-one + NADH + H(+)


name: sn-glycero-3-phospho-1D-myo-inositol + H2O <=> 1D-myo-inositol 1-phosphate + glycerol + H(+)


name: (2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Dictyostelium discoideum)


name: 1,2-diacyl-glycerol 3-phosphate + H2O => 1,2-diacyl-glycerol + orthophosphate (Saccharomyces cerevisiae)


name: Dissociation of RAS:RAF complex (Homo sapiens)


name: 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + dodecanoyl-CoA


name: dapdiamide C + ADP + phosphate + H(+) => N(3)-fumaramoyl-(S)-2,3-diaminopropanoate + L-leucine + ATP


name: Guanine + H2O => Xanthine + NH4+ (Drosophila melanogaster)


name: pyridine + S-adenosyl-L-methionine = N-methylpyridinium + S-adenosyl-L-homocysteine


name: Keratin filaments bind cell-cell adhesion complexes (Rattus norvegicus)


name: ROBO signaling pathway involved in muscle cell attraction


name: positive regulation of dUTP diphosphatase activity


name: Orexin 2 receptor can bind orexin-B neuropeptide (Gallus gallus)


name: MVD decarboxylates MVA5PP to IPPP (Canis familiaris)


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Rattus norvegicus)


name: torulene + O2 <=> 4'-apo-beta-carotenal + 3-methyl-2-butenal


name: Edg-4 lysophosphatidic acid receptor binding


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Homo sapiens)


name: 1-carboxyvinyl carboxyphosphonate + H(+) => 3-(hydrohydroxyphosphoryl)pyruvate + CO2


name: SGTA binds mislocalized membrane protein (Gallus gallus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate


name: p-RasGRP1,3:DAG cause RAS to exchange GDP for GTP (Danio rerio)


name: 3-methylnonanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxy-3-methylnonanoyl-CoA + succinate + CO2


name: docosanoate(in) + ATP + H2O => docosanoate(out) + ADP + phosphate + H(+)


name: 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 NADH + 2 H(+) => N,N-dimethyl-1,4-phenylenediamine + anthranilate + 2 NAD(+)


name: N,N-dimethylmescaline + S-adenosyl-L-homocysteine + H(+) => N-methylmescaline + S-adenosyl-L-methionine


name: apoTF binds 2Fe3+ to form holoTF (Drosophila melanogaster)


name: PIAS4 SUMOylates PARP1 with SUMO1 (Rattus norvegicus)


name: endosulfan hemisulfate sulfatase activity


name: 3-hydroxy-L-kynurenine + pyruvate <=> 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-alanine


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Danio rerio)


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Bos taurus)


name: glucoerucin + H2O = (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose


name: PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser (Homo sapiens)


name: WIPI2 binds ATG12:ATG5:ATG16L (Sus scrofa)


name: YAP1 binds TEAD4 (Caenorhabditis elegans)


name: CHAC1,2 cleaves GSH to OPRO and CysGly (Bos taurus)


name: norajmaline + S-adenosyl-L-methionine => ajmaline + S-adenosyl-L-homocysteine + H(+)


name: (2E)-2-butenoate + ATP + H(+) <=> (2E)-but-2-enoyl-AMP + diphosphate


name: cytidine(1962) in 23S rRNA + S-adenosyl-L-methionine => 5-methylcytidine(1962) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)


name: Activation of MT-MMPs by FURIN (Homo sapiens)


name: glycine + 2-oxoglutarate <=> glyoxylate + L-glutamate


name: N(2)-methylguanosine(10) in tRNA + S-adenosyl-L-methionine <=> N(2)-dimethylguanosine(10) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: (R)-malate + NAD(+) = pyruvate + CO2 + NADH


name: (3R)-hydroxynonanoyl-[ACP] + NADP(+) => 3-oxononanoyl-[ACP] + NADPH + H(+)


name: IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Canis familiaris)


name: beta-D-galactosyl-(1<->1')-N-octadecanoylsphing-4-enine + H2O => N-octadecanoylsphing-4-enine + D-galactose


name: [sulfur carrier]-H + biotin + 2 5'-deoxyadenosine + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] => (4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine


name: down regulation of metalloendoprotease activity


name: DTX4 ubiquitinates p-S172-TBK1 within NLRP4:DTX4:STING:TBK1:IRF3 (Rattus norvegicus)


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Mus musculus)


name: ubiquinol-8 + 2 O2 = 2 superoxide + ubiquinone-8 + 2 H(+)


name: N(1)-acetylspermine + H2O => spermine + acetate


name: hydrogenobyrinate a,c-diamide + 2 L-glutamate + 2 ADP + 2 phosphate + 2 H(+) => hydrogenobyrinate + 2 L-glutamine + 2 ATP + 2 H2O


name: L-phenylalanine + pyruvate <=> 3-phenylpyruvate + L-alanine


name: sphing-4-enine(in) + ATP + H2O => sphing-4-enine(out) + ADP + phosphate + H(+)


name: 16alpha,17beta-dihydroxyandrost-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => testosterone + reduced [NADPH--hemoprotein reductase] + O2


name: Interaction of other tyrosine kinases with p-KIT (Mus musculus)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate (Caenorhabditis elegans)


name: a (3R)-3-[(carboxymethyl)amino]fatty acid + 2 2-oxoglutarate + 2 O2 => a (3R)-3-isocyanyl-fatty acid + 2 succinate + 3 CO2 + 2 H2O


name: GLB1 hydrolyzes SapB/C:LacCer (Rattus norvegicus)


name: sphinga-4E,14Z-dienine-1-phosphate = (2E,12Z)-hexadecadienal + phosphoethanolamine


name: negative regulation of heptadecane biosynthetic process


name: 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + phosphate + H(+)


name: RHOG binds effectors at the plasma membrane (Xenopus tropicalis)


name: Association of RAD50:MRE11A complex with NBN (NBS1) via MRE11A interaction (Bos taurus)


name: Interleukin 2 Receptor-directed Antibody Interactions


name: (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) => isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: Platelet-activating factor acetylhydrolase (PLA2G7) hydrolyzes acyl Ghrelin (Canis familiaris)


name: FANCD2 binds FANCI (Drosophila melanogaster)


name: Interaction of integrin alpha9beta1 with VCAM1 (Sus scrofa)


name: ISGylation of protein phosphatase 1 beta (PP2CB) (Bos taurus)


name: RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 TMD/JMD mutants (Homo sapiens)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Schizosaccharomyces pombe)


name: NEUROG3-dependent synthesis of NKX2-2 (Homo sapiens)


name: prekainate + 2-oxoglutarate + O2 <=> kainate + succinate + CO2 + H2O


name: down regulation of protein phosphatase 3 activity


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-ethanolamine = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: mycothiol-dependent detoxification of alkylating agent


name: Fe(II)-heme o + A + H2O <=> Fe(II)-heme i + AH2


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Danio rerio)


name: (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a (9Z,11E,13E,15Z)-octadecatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Mus musculus)


name: Formation of the closed pre-initiation complex (Schizosaccharomyces pombe)


name: (1S,4S)-dihydrocarvone + NADH + H(+) => (1S,2S,4S)-dihydrocarveol + NAD(+)


name: p-Y705, S727 STAT3 dimer binds ICOS promoter (Homo sapiens)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Canis familiaris)


name: COQ6 hydroxylates DHB (Schizosaccharomyces pombe)


name: cAMP dissociates PKA, promoting GLI processing (Saccharomyces cerevisiae)


name: LPA-binding receptors bind LPA (Sus scrofa)


name: activation of protein ubiquitination activity


name: D-tyrosine + O2 + H2O <=> 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: D-glycero-beta-D-manno-heptose 7-phosphate + ATP => D-glycero-beta-D-manno-heptose 1,7-bisphosphate + ADP + H(+)


name: Transport of MHC heterotrimer to ER exit site (Gallus gallus)


name: a cytidine in 25S rRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in 25S rRNA + S-adenosyl-L-homocysteine + H(+)


name: TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)


name: ARMS is phosphorylated by active TrkA receptor (Rattus norvegicus)


name: growth hormone secretagogue receptor activity


name: GPVI stimulates PI3K beta, gamma (Sus scrofa)


name: Release of the RNP into the host cell nucleus (Homo sapiens)


name: Increased Brain Stem Enkephalin Activity


name: indolin-2-one + reduced [NADPH--hemoprotein reductase] + O2 => 3-hydroxyindolin-2-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: N-acetyl-L-glutamate 5-semialdehyde + phosphate + NADP(+) => N-acetyl-L-glutamyl 5-phosphate + NADPH + H(+)


name: Follitropin is a heterodimer (Xenopus tropicalis)


name: Calmodulin binds neurogranin (Homo sapiens)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Canis familiaris)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Mus musculus)


name: L-leucine + 8 malonyl-CoA + 4 S-adenosyl-L-methionine + ATP + 9 NADPH + 12 H(+) => (5S)-5-(2-methylpropyl)-3-[(2E,6R,8E,10E,12E)-6,8,10,12-tetramethyltetradeca-2,8,10,12-tetraenoyl]-2,5-dihydro-1H-pyrrol-2-one + AMP + 4 S-adenosyl-L-homocysteine + 8 CO2 + diphosphate + 9 NADP(+) + 8 CoA + 7 H2O


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)


name: p-EPHB phosphorylates SDC2 (Caenorhabditis elegans)


name: 5-methoxytryptamine + acetyl-CoA = melatonin + CoA + H(+)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Mus musculus)


name: hexacosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-hexacosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: (2R)-2-phosphoglycerate + H2O <=> (R)-glycerate + phosphate


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Xenopus tropicalis)


name: TFAP2C homodimer binds MYC and KDM5B (Bos taurus)


name: a medium-chain primary fatty alcohol + NADP(+) <=> a medium-chain fatty aldehyde + NADPH + H(+)


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Bos taurus)


name: SRC-1 bound to ARRB2 is not activated (Gallus gallus)


name: alpha-D-ribose 1-phosphate + ATP <=> alpha-D-ribose 1,5-bisphosphate + ADP + H(+)


name: PIPOX oxidises PPCA to P6C (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 <=> (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O


name: DAG is acylated to TAG by DGAT1/2 (Caenorhabditis elegans)


name: 32-oxolanosterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => 32-hydroxylanosterol + reduced [NADPH--hemoprotein reductase] + O2


name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Canis familiaris)


name: UGTs glucuronate APAP to APAP-GlcA (Bos taurus)


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Bos taurus)


name: OTUD7A hydrolyses K11diUb (Homo sapiens)


name: salicylate + NADH + O2 + H(+) = 2,3-dihydroxybenzoate + NAD(+) + H2O


name: a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O => a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + sulfate + H(+)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Sus scrofa)


name: 5-dehydro-D-gluconate(in) + H(+)(in) <=> 5-dehydro-D-gluconate(out) + H(+)(out)


name: a 7-O-hydroxy-flavonol + UDP-alpha-D-glucose = a flavonol 7-O-beta-D-glucoside + UDP + H(+)


name: MERTK receptor binds ligands (Gas6 or Protein S) (Rattus norvegicus)


name: ITGBL1 gene expression is stimulated by RUNX2 (Homo sapiens)


name: SLC25A16 transports cytosolic CoA-SH to mitochondrial matrix (Saccharomyces cerevisiae)


name: Increased Striated Muscle Enkephalin Activity


name: ME2 tetramer decarboxylates MAL to PYR (Mus musculus)


name: PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Mus musculus)


name: Caspase mediated cleavage of HIP-55 (Caenorhabditis elegans)


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Canis familiaris)


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Xenopus tropicalis)


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O => (-)-geosmin + acetone


name: 4-methylcyclohexanone + NH4(+) + NADPH + H(+) => 4-methyl-cyclohexylamine + NADP(+) + H2O


name: (-)-matairesinol + reduced [NADPH--hemoprotein reductase] + O2 => (-)-pluviatolide + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: LIPT2 transfers octanoyl group to GCSH (Caenorhabditis elegans)


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Rattus norvegicus)


name: pyrimidine deoxyribonucleoside 2'-hydroxylase activity


name: tRNA(Trp) + D-tryptophan => D-tryptophanyl-tRNA(Trp) + H2O


name: p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Drosophila melanogaster)


name: IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Bos taurus)


name: trilobatin + UDP + H(+) => phloretin + UDP-alpha-D-glucose


name: (3R)-hydroxy-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA => (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA + H2O


name: Exocytosis of secretory granule membrane proteins (Sus scrofa)


name: pseudomonoyl-CoA C + holothin <=> pseudomonic acid C--holothin + CoA


name: Dopachrome is transformed to DHICA by DCT (Homo sapiens)


name: Ubiquitination of IKBKG by TRAF6 (Canis familiaris)


name: Keratin filament formation (Rattus norvegicus)


name: rhazimol + NADP(+) => rhazimal + NADPH + 2 H(+)


name: 2 superoxide + menaquinone-8 + 2 H(+) => menaquinol-8 + 2 O2


name: heptanoyl-CoA + AMP + diphosphate => heptanoate + ATP + CoA


name: PPP1CC dephosphorylates PLK1 (Sus scrofa)


name: 3-methoxytyramine + S-adenosyl-L-homocysteine + H(+) => dopamine + S-adenosyl-L-methionine


name: (S)-3-hydroxyisobutanoyl-CoA + H2O <=> (S)-3-hydroxy-2-methylpropanoate + CoA + H(+)


name: N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[glycine-cleavage complex H protein] + CO2


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Caenorhabditis elegans)


name: an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoinositol + a 1,2-diacyl-sn-glycerol


name: AKT binds PDPK1 (Drosophila melanogaster)


name: (R)-metanephrine + S-adenosyl-L-homocysteine + H(+) => (R)-normetanephrine + S-adenosyl-L-methionine


name: Ca permeable AMPA receptor ligand binding (Gallus gallus)


name: 6alpha-hydroxy-28-nortyphasterol + reduced [NADPH--hemoprotein reductase] + O2 = 28-nortyphasterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: (-)-kolavenyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: (Z)-1,2-dichloroethene + AH2 = chloroethene + chloride + A + H(+)


name: p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Mus musculus)


name: N-dodecanoylethanolamine + H2O => dodecanoate + ethanolamine


name: positive regulation of 'de novo' NAD biosynthetic process from tryptophan


name: ELANE, CTSG or PRTN3 binds bacteria (Rattus norvegicus)


name: TRMT44 2'-O-methylates uridine-44 in tRNA(Ser) (Homo sapiens)


name: BGN binds Collagen types I, VI, (IX) (Mus musculus)


name: NOTCH3-ligand complex is cleaved to produce NEXT3 (Rattus norvegicus)


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + H2O = [(1->4)-N-acetyl-beta-D-glucosaminyl](n-2) + N,N'-diacetylchitobiose


name: Binding of TFIIE to the growing preinitiation complex (Mus musculus)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)


name: 3-acetylamino-4-hydroxybenzoate + CoA => 3-amino-4-hydroxybenzoate + acetyl-CoA


name: Thrombin-activated PARs:Gq (active) dissociate (Xenopus tropicalis)


name: Caspase cleavage of DCC (Xenopus tropicalis)


name: (2Z,4Z)-2,3-dichloromuconate + 2 H(+) => 3,4-dichlorocatechol + O2


name: ROBO/SLIT signaling pathway involved in axon growth cone guidance


name: COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides (Gallus gallus)


name: CCND1 binds RUNX3 and displaces EP300 (Canis familiaris)


name: Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)


name: RAS activation by SOS1 bound to phosphorylated heterodimers of ERBB2 KD mutants (Homo sapiens)


name: (9Z,12Z)-octadecadienoate + CoA + H(+) => (9Z,12Z)-octadecadienoyl-CoA + H2O


name: L-asparagine(out) + L-glutamine(in) + Na(+)(in) => L-asparagine(in) + L-glutamine(out) + Na(+)(out)


name: 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA => 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA


name: G beta-gamma complex and PIP3 recruit BTK to membrane (Gallus gallus)


name: adenosine 2',5'-bisphosphate + H2O => AMP + phosphate


name: N-methyl-D-dopa + O2 <=> (3R)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2


name: 2,4-dinitrotoluene + 2 NADPH + 2 H(+) <=> 4-hydroxylamino-2-nitrotoluene + 2 NADP(+) + H2O


name: Activation of claspin (Rattus norvegicus)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (9Z)-octadecenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: RUNX2-P2 binds RUNX2 gene promoter (Homo sapiens)


name: SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Canis familiaris)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + glycine <=> N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + CoA + H(+)


name: K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Mus musculus)


name: FA2H hydroxylates 1,2-saturated fatty acids (Schizosaccharomyces pombe)


name: 3-hydroxyacyl-CoA-acyl carrier protein transferase activity


name: SENP1,2,5 proteolytically process SUMO3 (Rattus norvegicus)


name: isopentenyl diphosphate + dimethylallyl diphosphate = (2E)-geranyl diphosphate + diphosphate


name: CYPs hydroxylate DHA to 14(R)-HDHA (Canis familiaris)


name: succinate(out) + phosphate(in) <=> succinate(in) + phosphate(out)


name: 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA) (Sus scrofa)


name: 2-oxoglutarate + NADH + 2 H(+) => 2,5-dioxopentanoate + NAD(+) + H2O


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP => 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Gamma-carboxy pro-factor X transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: PHLPP dephosphorylates S473 in AKT (Homo sapiens)


name: 2-deoxy-alpha-D-ribose 1-phosphate <=> 2-deoxy-D-ribose 5-phosphate


name: 6-oxocyclohex-1-ene-1-carbonyl-CoA + H2O => 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA


name: 3-hydroxypropionate dehydrogenase (NADP+) activity


name: (9S,10S)-10-hydroxy-9-(phosphooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate


name: 3-oxopropanoate + L-alanine <=> beta-alanine + pyruvate


name: GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+) => GDP-6-deoxy-alpha-D-talose + NADP(+)


name: PIAS1,3 SUMOylate MBD1 with SUMO1 (Xenopus tropicalis)


name: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Canis familiaris)


name: aspartic endopeptidase activity, intramembrane cleaving


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Sus scrofa)


name: Phosphorylation of YAP by LATS2 (Canis familiaris)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Caenorhabditis elegans)


name: 2-oxoaldehyde dehydrogenase (NAD+) activity


name: Protein Kinase B/Akt phosphorylates BRF1 (Homo sapiens)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Rattus norvegicus)


name: umbelliferone + dimethylallyl diphosphate <=> osthenol + diphosphate


name: (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + a ribonucleoside 5'-diphosphate + H(+) => an NDP-alpha-D-glucose + (2R)-3-phosphoglycerate


name: tetradecanoate + O2 <=> (2R)-2-hydroperoxytetradecanoate


name: N(alpha),N(alpha),N(alpha)-trimethyl-L-tryptophan + S-adenosyl-L-homocysteine + H(+) => N(alpha),N(alpha)-dimethyl-L-tryptophan + S-adenosyl-L-methionine


name: a 1-acyl-sn-glycero-3-phosphocholine + H2O <=> sn-glycerol 3-phosphocholine + a fatty acid + H(+)


name: Addition of a GlcNAc on the alpha 1,4 branch by MGAT2 (Xenopus tropicalis)


name: Thr-180 of ULK1 is phosphorylated (Rattus norvegicus)


name: 2-glyceryl-prostaglandin G2 + AH2 <=> 2-glyceryl-prostaglandin H2 + A + H2O


name: CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1 (Bos taurus)


name: cadystin transmembrane transporter activity


name: CBL ubiquitinates FRS2 and FGFR4 (Bos taurus)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Danio rerio)


name: (R,R)-butane-2,3-diol + NAD(+) = (R)-acetoin + NADH + H(+)


name: N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine + 2 H(+) => L-lysine + 2 S-adenosyl-L-methionine


name: a ubiquinone + D-glucose <=> D-glucono-1,5-lactone + a ubiquinol


name: PKC phosphorylates sphingosine kinase 1 (Canis familiaris)


name: N-(2-hydroxydocosanoyl)-sphinganine + CoA + H(+) => 2-hydroxydocosanoyl-CoA + sphinganine


name: Formation of translation initiation complexes containing mRNA that does not circularize (Bos taurus)


name: SEMA4D interacts with Plexin-B1:Met (Sus scrofa)


name: zealexin A1 + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+) => (S)-beta-macrocarpene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2


name: hancockiamide A + acetyl-CoA => hancockiamide B + CoA + H(+)


name: "Kdo2-lipid A phosphoethanolamine 7''-transferase"


name: XPC binds RAD23 and CETN2 (Canis familiaris)


name: N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+) => L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Rattus norvegicus)


name: NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs (Homo sapiens)


name: CTDNEP1:CNEP1R1 dephosphorylates LPIN (Caenorhabditis elegans)


name: COX10 transforms heme to heme O (Schizosaccharomyces pombe)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline


name: an aromatic L-alpha-amino acid(out) + 3,3',5-triiodo-L-thyronine(in) => an aromatic L-alpha-amino acid(in) + 3,3',5-triiodo-L-thyronine(out)


name: SERPINC1 binds SERPINC1 activators (Mus musculus)


name: nucleobase-containing compound transmembrane transporter activity


name: Exocytosis of azurophil granule lumen proteins (Gallus gallus)


name: N-terminal L-valyl-[protein] + acetyl-CoA <=> N-terminal N(alpha)-acetyl-L-valyl-[protein] + CoA + H(+)


name: 6-dehydro-28-norteasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => 3-dehydro-6alpha-hydroxy-28-norteasterone + reduced [NADPH--hemoprotein reductase] + O2


name: hexadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) <=> 4-hydroxy-6-(2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: PEBP1 binds activated RAF1 (Caenorhabditis elegans)


name: ROBOs bind keratan sulfate (Homo sapiens)


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Danio rerio)


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Rattus norvegicus)


name: I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Caenorhabditis elegans)


name: 6-methyl-3,7-dioxodecanedioyl-CoA + CoA => 4-methyl-5-oxo-octanedioyl-CoA + acetyl-CoA


name: N-hexacosanoylsphinganine + NADPH + O2 + H(+) = N-(2-hydroxyhexacosanoyl)-sphinganine + NADP(+) + H2O


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Danio rerio)


name: SUMOylation of UBE2I with SUMO1 (Sus scrofa)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine => 1-O-(1Z)-alkenyl-2-hexadecanoyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  (Rattus norvegicus)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP (Sus scrofa)


name: hypobromite + L-tyrosyl-[protein] + H(+) => 3-bromo-L-tyrosyl-[protein] + H2O


name: alpha-D-glucose 1-phosphate + ATP <=> alpha-D-glucose 1,6-bisphosphate + ADP + H(+)


name: 2-AG hydrolysis to arachidonate by MAGL (Bos taurus)


name: SLC6A18 transports Gly from extracellular region to cytosol (Drosophila melanogaster)


name: cAMP activates EPAC1 (Saccharomyces cerevisiae)


name: Tropoelastin forms aggregate globules (Bos taurus)


name: (+)-guaia-6,9-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: PCSK6,FURIN mediate dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Gallus gallus)


name: (R)-3-phosphomevalonate + ATP = (R)-3,5-bisphosphomevalonate + ADP + H(+)


name: Expression of TFAP2A in the neural plate border (Homo sapiens)


name: Frataxin transfers Fe2+ to ACO2 (Bos taurus)


name: D-maltoheptaose + H2O = D-maltohexaose + alpha-D-glucose


name: Ceramide synthases transfer acyl-CoA onto sphingoid (Saccharomyces cerevisiae)


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Canis familiaris)


name: N-acetylglucosamine transmembrane transporter activity


name: a (Z)-alkenyl glucosinolate + H2O => a (Z)-N-(sulfonatooxy)alkenimidothioate + D-glucose + H(+)


name: a neolactoside IV(3)-alpha-GalNAc,IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + H2O <=> a neolactoside IV(2)-alpha-Fuc-nLc4Cer(d18:1(4E)) + N-acetyl-alpha-D-galactosamine


name: (2E,6E)-farnesyl diphosphate <=> (+)-eremophilene + diphosphate


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)


name: ethyl benzoate + CoA => ethanol + benzoyl-CoA


name: POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Gallus gallus)


name: hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2 (Sus scrofa)


name: RHOC activates endoplasmic reticulum effectors (Saccharomyces cerevisiae)


name: negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding


name: ALDH3B2 oxidises HXAL to PALM (Danio rerio)


name: Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex (Sus scrofa)


name: siccayne + dimethylallyl diphosphate <=> pestalodiol + diphosphate


name: Glycosylation of Pre-NOTCH by FRINGE (Homo sapiens)


name: GSTO dimers reduce DeHA to AscH- (Caenorhabditis elegans)


name: SPRY2 translocates to the plasma membrane (Bos taurus)


name: protein-phosphocysteine-glucosamine phosphotransferase system transporter activity


name: a ganglioside GD1b + UDP + H(+) => a ganglioside GD2 + UDP-alpha-D-galactose


name: Insulin receptor de-phosphorylation (Gallus gallus)


name: alpha,alpha-trehalose + H2O <=> alpha-D-glucose + beta-D-glucose


name: dolichyl phosphate + GDP-alpha-D-mannose -> dolichyl phosphate D-mannose (Danio rerio)


name: (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine => 4-(trimethylamino)butanal + glycine


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Sus scrofa)


name: butanoyl-CoA + O2 => (2E)-butenoyl-CoA + H2O2


name: TRIKA2 binds K63polyUb-TRAF6 oligomer (Rattus norvegicus)


name: CARNMT1 methylates CARN to Anserine (Rattus norvegicus)


name: (R)-2-hydroxyoctadecanoate + NAD(+) => 2-oxooctadecanoate + NADH + H(+)


name: factor XI + platelet glycoprotein (GP) Ib:IX:V complex -> factor XI:platelet glycoprotein (GP) Ib:IX:V complex (Rattus norvegicus)


name: MMP14:TIMP2 binds proMMP2 (Drosophila melanogaster)


name: GNLY is transferred to the phagosome (Gallus gallus)


name: Complement factor I inactivates C4BP-bound C4b (Homo sapiens)


name: IL37(?-218) translocates from the cytosol to the nucleus (Homo sapiens)


name: deoxycholate + UDP-alpha-D-glucuronate <=> deoxycholoyl-24-O-(beta-D-glucuronate) + UDP


name: ITP + oxaloacetate <=> IDP + phosphoenolpyruvate + CO2


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Caenorhabditis elegans)


name: AKT1 dephosphorylation by PP2A-B56-beta,gamma (Homo sapiens)


name: chloride(in) + Na(+)(in) => chloride(out) + Na(+)(out)


name: 3,4-dihydroxyphthalate + H(+) => 3,4-dihydroxybenzoate + CO2


name: syringetin + S-adenosyl-L-homocysteine + H(+) => laricitrin + S-adenosyl-L-methionine


name: a 1-(9Z-octadecenoyl)-2-acyl-sn-glycero-3-phosphocholine + H2O => a 2-acyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)


name: formate + CoA + H(+) => formyl-CoA + H2O


name: salicylate + ATP + H(+) => 2-hydroxybenzoyl-5'-AMP + diphosphate


name: CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds STAT1,3,5 (Homo sapiens)


name: raucaffrinoline + NADP(+) <=> perakine + NADPH + H(+)


name: PTGIS, CYP8A1 isomerise PGH2 to PGI2 (Rattus norvegicus)


name: Oxidative dealkylation of 1-etA damaged DNA By ALKBH2 (Homo sapiens)


name: Vamp8 associated secretory vesicle to plasma membrane transport (Drosophila melanogaster)


name: 5alpha-androst-1-ene-3,17-dione + A = androsta-1,4-diene-3,17-dione + AH2


name: PIAS1,3 SUMOylates NR5A1 with SUMO1 (Bos taurus)


name: G alpha (z) inhibits adenylate cyclase (Dictyostelium discoideum)


name: XYLB phosphorylates D-xylulose (Canis familiaris)


name: (2R)-2-amino-2-carboxylatoethyl-disulfanyl-oxopropanoate + H2O2 + NH4(+) => L-cystine + O2 + H2O


name: DIBOA + UDP-alpha-D-glucose <=> DIBOA beta-D-glucoside + UDP + H(+)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: fumarate(in) + L-aspartate(out) = fumarate(out) + L-aspartate(in)


name: nonanoyl-AMP + CoA => nonanoyl-CoA + AMP + H(+)


name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Canis familiaris)


name: 1,7-dimethylxanthine + NADPH + O2 + H(+) => 7-methylxanthine + formaldehyde + NADP(+) + H2O


name: positive regulation of phenazine biosynthetic process


name: cya and lef bind to pagA(197-794):ANTXR1 oligomer (Homo sapiens)


name: Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Schizosaccharomyces pombe)


name: UMPS dimer decarboxylates OMP to UMP (Drosophila melanogaster)


name: coenzyme F430 + ADP + phosphate => 15,17(3)-seco-F430-17(3)-acid + ATP


name: cytidine(50) in tRNA + S-adenosyl-L-methionine <=> 5-methylcytidine(50) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: TRAF2,6 ubiquitinates NLRC5 (Canis familiaris)


name: Mitogen-Activated Protein Kinase Kinase Inhibitors [MoA]


name: (4R)-hydroxysphinganine + a fatty acyl-CoA = an N-acyl-(4R)-4-hydroxysphinganine + CoA + H(+)


name: transferase activity, transferring one-carbon groups


name: UBA1 adenylates ubiquitin in the nucleoplasm (Mus musculus)


name: N-hydroxylation of 4-aminobiphenyl (Rattus norvegicus)


name: malonyl-CoA methyl ester + S-adenosyl-L-homocysteine => malonyl-CoA + S-adenosyl-L-methionine


name: MRE11 binds cytosolic DNA (Drosophila melanogaster)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Saccharomyces cerevisiae)


name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA (Mus musculus)


name: 2 [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 = [thyroglobulin]-L-thyroxine + [thyroglobulin]-dehydroalanine + 2 H2O


name: 2-methylhexadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) => 4-hydroxy-6-(3-methyl-2-oxoheptadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Danio rerio)


name: Full activation of MMP1 (Xenopus tropicalis)


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Sus scrofa)


name: L-amino acyl-L-threonyl-[protein] + ATP = (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + ADP + phosphate + H(+)


name: pyruvate + phosphate + O2 + H(+) = acetyl phosphate + H2O2 + CO2


name: (11Z,14Z)-eicosadienamide + H2O => (11Z,14Z)-eicosadienoate + NH4(+)


name: GBA1:SAPC hydrolyzes GlcCer (Caenorhabditis elegans)


name: a neolactoside nLc4Cer(d18:1(4E)) + UDP-N-acetyl-alpha-D-glucosamine = a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP + H(+)


name: regulation of 1-naphthol glucuronyltransferase activity


name: 2-methoxy-17beta-estradiol + UDP-alpha-D-glucuronate => 2-methoxy-17beta-estradiol 3-O-(beta-D-glucuronate) + UDP + H(+)


name: Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Caenorhabditis elegans)


name: dUTP + 2 H2O => dUMP + 2 phosphate + 2 H(+)


name: positive regulation of substance P receptor ligand


name: pelargonidin + UDP-alpha-D-glucose => pelargonidin 3-O-beta-D-glucoside + UDP


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Bos taurus)


name: DPH2 transfers a 3-amino-3-carboxypropyl group from AdoMet to residue 715 of nascent EEF2 (Drosophila melanogaster)


name: SERPING1 is secreted (Rattus norvegicus)


name: Active LTK receptor phosphorylates SHC1 (Xenopus tropicalis)


name: (9Z,12Z,15Z)-octadecatrienoate + ATP + CoA => (9Z,12Z,15Z)-octadecatrienoyl-CoA + AMP + diphosphate


name: TRAF6 binds to hp- IRAK1/or p-IRAK2:p-IRAK4:MyD88:activated TLR7/8 or 9   (Homo sapiens)


name: PIP3 recruits PDK1 and AKT to the membrane (Rattus norvegicus)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Drosophila melanogaster)


name: TP53 binds STK11 and NUAK1 (Rattus norvegicus)


name: 3,3',5'-triiodo-L-thyronine + 3'-phosphoadenylyl sulfate => 3,3',5'-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: dimethylarsinous acid + 2 [thioredoxin]-disulfide + 3 glutathione + 2 S-adenosyl-L-homocysteine + 2 H(+) => arsenic triglutathione + 2 [thioredoxin]-dithiol + 2 S-adenosyl-L-methionine + H2O


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)


name: Activation of PAKs by RAC1 and CDC42 (Bos taurus)


name: hydroxyurea + O-acetyl-L-serine = O-ureido-L-serine + acetate + H(+)


name: p-Y701-STAT1:p-Y705-STAT3 translocates to the nucleus (Sus scrofa)


name: L-ectoine + H2O => (2S)-2-acetamido-4-aminobutanoate


name: ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential


name: Inactive BRAF mutants:mutant RAS:GTP bind RAF1 (Homo sapiens)


name: Engulfed CpG DNA binds to endosomal N-ter TLR9 dimer (Bos taurus)


name: butan-2-one + NADH + O2 + H(+) <=> 1-hydroxy-2-butanone + NAD(+) + H2O


name: B3GNT1,2,3,4,7 add GlcNAc to form Keratan-PG (Drosophila melanogaster)


name: a ganglioside GA1 + GDP-beta-L-fucose <=> a ganglioside Fuc-GA1 + GDP + H(+)


name: CDC6 association with ORC(1-6) at replication origins (Dictyostelium discoideum)


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Canis familiaris)


name: an acetyl ester + H2O => an aliphatic alcohol + acetate + H(+)


name: LDLR transports extracellular CR:atREs to cytosol  (Homo sapiens)


name: an aldehyde + NADPH + H(+) => a primary alcohol + NADP(+)


name: (2E,7Z)-hexadecadienoyl-CoA + H2O => (3S)-hydroxy-(7Z-hexadecenoyl)-CoA


name: CYPs hydroxylate DHA to 14(R)-HDHA (Homo sapiens)


name: L-isoleucine-(+)-12-hydroxy-7-isojasmonate + NADP(+) + H2O => L-isoleucine-(+)-7-isojasmonate + NADPH + O2 + H(+)


name: (Z)-2-((N-methylformamido)methylene)-5-hydroxybutanolactone + FMN + H(+) => N-methylnicotinate + FMNH2 + O2


name: UBA1 adenylates ubiquitin in the nucleoplasm (Caenorhabditis elegans)


name: a ganglioside GA2 + UDP-alpha-D-galactose = a ganglioside GA1 + UDP + H(+)


name: PDPK1 binds PIP2 (Plasmodium falciparum)


name: D-cystine(out) + ATP + H2O = D-cystine(in) + ADP + phosphate + H(+)


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Bos taurus)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Sus scrofa)


name: Disassociation of CLIP from MHC II (Bos taurus)


name: pseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-methionine => N(1)-methylpseudouridine(1191) in yeast 18S rRNA + S-adenosyl-L-homocysteine + H(+)


name: D-allulose 6-phosphate <=> keto-D-fructose 6-phosphate


name: RASA1 stimulates RAS GTPase activity (Mus musculus)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GM1 (d18:1(4E)) + CMP + H(+)


name: ligand-dependent nuclear receptor activity


name: benzyl alcohol + L-leucine + CO2 => N-benzyloxycarbonyl-L-leucine + H2O + H(+)


name: Phosphorylation and activation of eIF4G by activated S6K1 (Bos taurus)


name: a 3',5'-unsubstituted flavanone + reduced [NADPH--hemoprotein reductase] + O2 => a 3'-hydroxy,5'-unsubstituted flavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (E)-4-coumaroyl-CoA + NADPH + H(+) => (E)-4-coumaraldehyde + NADP(+) + CoA


name: N-hydroxy-L-dihomomethionine + reduced [NADPH--hemoprotein reductase] + O2 = N,N-dihydroxy-L-dihomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA


name: ESTG binds ESR1:chaperone complex (Homo sapiens)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Bos taurus)


name: 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecenyl)-2,3-di-(9Z-octadecenoyl)glycerol + CoA


name: MYC/MYCN bind the ALK gene (Homo sapiens)


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Gallus gallus)


name: ALK binds ligand pleiotrophin (PTN) (Canis familiaris)


name: an adenosine in mRNA + formaldehyde + succinate + CO2 => an N(1)-methyladenosine in mRNA + 2-oxoglutarate + O2


name: 3-indoleglycolaldehyde + NH4(+) + CO2 => L-tryptophan + O2 + H(+)


name: Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Caenorhabditis elegans)


name: an N-(ADP-alpha-D-ribosyl)-thymidine in DNA + H2O => a thymidine in DNA + ADP-D-ribose


name: NEXT3 is cleaved to produce NICD3 (Rattus norvegicus)


name: an alpha-Kdo-(2->6)-lipid IVA + ATP = a 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA + ADP + H(+)


name: Increased Autonomic Nervous System Dopamine Activity


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Mus musculus)


name: L-tyrosine + 2-oxoglutarate => 3-(4-hydroxyphenyl)pyruvate + L-glutamate


name: factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) (Gallus gallus)


name: a tRNA precursor + 2 CTP => a tRNA with a 3' CC end + 2 diphosphate


name: dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Sus scrofa)


name: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH2


name: TREX complex binds spliced, capped mRNA:CBC:EJC cotranscriptionally (Mus musculus)


name: MKL1 translocates from cytosol to the nucleus (Sus scrofa)


name: 14-3-3 Binds p-S237-TBC1D1 (Homo sapiens)


name: vomilenine + UDP-alpha-D-glucose = raucaffricine + UDP + H(+)


name: 1-O-(9Z)-octadecenoyl-2-O-acetyl-sn-glycero-3-phosphocholine + H2O => 2-acetyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)


name: NUDT1 hydrolyses 2-oxo-ATP to 2-oxo-AMP (Plasmodium falciparum)


name: GGPS1 hexamer transfers IPPP to GPP (Rattus norvegicus)


name: PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Homo sapiens)


name: (S)-lactate(out) + 2 Na(+)(out) => (S)-lactate(in) + 2 Na(+)(in)


name: Activated FGFR1:p-FRS bind to PPTN11 (Mus musculus)


name: LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 (Homo sapiens)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Plasmodium falciparum)


name: phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 (Bos taurus)


name: O-phospho-L-serine + H2O <=> L-serine + phosphate


name: Activation of Ca permeable AMPA receptors (Drosophila melanogaster)


name: a ganglioside GD1alpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1aalpha (d18:1(4E)) + CMP + H(+)


name: RAC2:GTP binds NOX2 complex (Canis familiaris)


name: quinolin-5-ol + A + H2O = 5-hydroxyquinolin-2(1H)-one + AH2


name: 3-oxotetradecanoyl-[ACP] + holo-[ACP] + CO2 => dodecanoyl-[ACP] + malonyl-[ACP] + H(+)


name: PARP1 binds SMAD2/3:SMAD4 heterotrimer (Bos taurus)


name: VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)


name: Phosphorylation of CRMPs by Cdk5 (Caenorhabditis elegans)


name: GNPDA1,2 hexamers deaminate GlcN6P to Fru(6)P (Homo sapiens)


name: dIMP + H2O => 2'-deoxyinosine + phosphate


name: cyclin-dependent protein kinase, intrinsic regulator activity


name: PXLP-K754-GLDC dimer decarboxylates Gly (Saccharomyces cerevisiae)


name: prekainate + 2-oxoglutarate + O2 = kainate + succinate + CO2 + H2O


name: (9Z)-octadecenoyl-[ACP] + H2O => (9Z)-octadecenoate + holo-[ACP] + H(+)


name: a 2-demethylmenaquinol + S-adenosyl-L-methionine => a menaquinol + S-adenosyl-L-homocysteine + H(+)


name: cadaverine + O2 + H2O => 5-aminopentanal + H2O2 + NH4(+)


name: ACER3 hydrolyzes phytoceramide (Saccharomyces cerevisiae)


name: Activation of RAC1 by SOS (Homo sapiens)


name: TCF:Beta-catenin binds SOX proteins (Caenorhabditis elegans)


name: octane + 2 reduced [rubredoxin] + O2 + 2 H(+) => 2 oxidized [rubredoxin] + octan-1-ol + H2O


name: N(pros)-phospho-L-histidyl-[protein] + H2O <=> L-histidyl-[protein] + phosphate


name: 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol + 3'-phosphoadenylyl sulfate => 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine + CMP + H(+) => CDP-2,3-bis-O-(phytanyl)-sn-glycerol + L-serine


name: gamma-tocopherol + NADPH + O2 + H(+) = 13-hydroxy-gamma-tocopherol + NADP(+) + H2O


name: GST dimers cleave AZA to 6MP (Xenopus tropicalis)


name: D-mannonate + NAD(+) => keto-D-fructuronate + NADH + H(+)


name: a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => a 1-[(9Z,12Z,15Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: 5-deoxy-D-ribulose 1-phosphate <=> dihydroxyacetone phosphate + acetaldehyde


name: p-T38-PPP1R14A binds MLCP (Xenopus tropicalis)


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Homo sapiens)


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Bos taurus)


name: orotidine 5'-phosphate + diphosphate <=> orotate + 5-phospho-alpha-D-ribose 1-diphosphate


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Sus scrofa)


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] <=> N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] + H2O


name: a very-long-chain 2,3-saturated fatty acyl-CoA + O2 => a very-long-chain (2E)-enoyl-CoA + H2O2


name: abscisic acid-activated signaling pathway


name: GBF1 recruits ARF:GDP to the ERGIC (Dictyostelium discoideum)


name: NEIL1,NEIL2 recruits POLB to incised AP site (Xenopus tropicalis)


name: D-allulose 6-phosphate => D-allose 6-phosphate


name: MHC class I protein binding, via lateral surface


name: ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex (Homo sapiens)


name: Orc1 is phosphorylated by cyclin A/CDK2 (Caenorhabditis elegans)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O = 1-O-alkyl-2-acyl-sn-glycerol + phosphate


name: (1R,2R,3R)-prephytoene diphosphate = 15-cis-phytoene + diphosphate


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Danio rerio)


name: ESR1:ESTG and EP300 are recruited to TFF3 promoter (Sus scrofa)


name: AP-1 complex stimulates KDM6B transcription (Homo sapiens)


name: D-galactose + O2 = D-galacto-hexodialdose + H2O2


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Bos taurus)


name: FGFR2b binds to FGF (Caenorhabditis elegans)


name: phosphatidylinositol trisphosphate phosphatase activity


name: Release of p-STAT2:p-STAT1 dimer (Canis familiaris)


name: UCKL1 phosphorylates urindine, cytidine (Dictyostelium discoideum)


name: ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Schizosaccharomyces pombe)


name: 2-phosphoglycolate + (2R)-3-phosphoglycerate + 2 H(+) => D-ribulose 1,5-bisphosphate + O2


name: 6-deoxo-28-nortyphasterol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 => 28-nortyphasterol + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)


name: AMBRA1 binds DYNLL1,DYNLL2 (Rattus norvegicus)


name: 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O => 3-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoate + H(+)


name: ALOX12 oxidises LTA4 to LXB4 (Dictyostelium discoideum)


name: FMN(out) + adenosine 3',5'-bisphosphate(in) => FMN(in) + adenosine 3',5'-bisphosphate(out)


name: a 5'-end dephospho-uridine-RNA + a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA => ribonucleotidyl-uridine-RNA


name: CLEC2B binds KLRF1 dimer (Canis familiaris)


name: CUL3:RBX1 ubiquitinates KEAP1 (Caenorhabditis elegans)


name: 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate (Schizosaccharomyces pombe)


name: pro-SFTPC translocates from ER membrane to multivesicle body (Gallus gallus)


name: K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Rattus norvegicus)


name: 1,2-dihexanoylglycerol + octadecanoyl-CoA <=> 1,2-dihexanoyl-3-octadecanoylglycerol + CoA


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Rattus norvegicus)


name: scutellarein + S-adenosyl-L-methionine = scutellarein 7-methyl ether + S-adenosyl-L-homocysteine


name: Defective SLC40A1 does not transport Fe2+ from cytosol to extracellular region (Homo sapiens)


name: estrone + reduced [NADPH--hemoprotein reductase] + O2 => 16alpha-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: α1-agonists bind ADRA1A,B,D (Caenorhabditis elegans)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Dictyostelium discoideum)


name: JAK1-activated RAF1 phosphorylates MAPKs (Homo sapiens)


name: Mg-protoporphyrin IX + ADP + phosphate + 3 H(+) => protoporphyrin IX + Mg(2+) + ATP + H2O


name: Homocysteine is degraded to oxobutanoate and H2S (Canis familiaris)


name: MYSM1 deubiquitinates Histone H2A (Danio rerio)


name: tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 => 13-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: HSD11B1 hydrogenates PREDN to PREDL in hepatic cell (Xenopus tropicalis)


name: silphinene-15-oate + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 <=> gamma-lactone-2-keto[5.5.5.5]fenestrane + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+)


name: protein tyrosine kinase inhibitor activity


name: pentalenene + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) <=> pentalen-13-al + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O


name: Excision of FapyG by OGG1 glycosylase (Drosophila melanogaster)


name: SLC7A8-mediated uptake of neutral amino acids (Homo sapiens)


name: CYTH proteins stimulate ARF1 GTPase activity (Mus musculus)


name: ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance


name: 2 hydrogencarbonate(out) + chloride(in) + Na(+)(out) = 2 hydrogencarbonate(in) + chloride(out) + Na(+)(in)


name: xanthogalenol + S-adenosyl-L-methionine <=> 4'-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)


name: Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)


name: hydroquinone + NAD(+) + H2O => phenol + NADH + O2 + H(+)


name: 4-hydroxyestrone + UDP-alpha-D-glucuronate = estrone 4-O-(beta-D-glucuronate) + UDP + H(+)


name: PETA is dephosphorylated to ETA by PHOSPHO1 (Xenopus tropicalis)


name: Polyubiquitinated RUNX3 translocates to the cytosol (Caenorhabditis elegans)


name: (17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + 2 glutathione = (17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + glutathione disulfide + H2O


name: 5-N(alpha)-glycyl-dTMP in DNA + AH2 + S-adenosyl-L-methionine = 5-C(alpha)-glycyl-dTMP in DNA + 5'-deoxyadenosine + L-methionine + A + H(+)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Gallus gallus)


name: MAOA:FAD oxidatively deaminates of 5HT (Rattus norvegicus)


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Bos taurus)


name: caffeine + a ubiquinone + H2O = 1,3,7-trimethylurate + a ubiquinol


name: (2E,6E)-farnesyl diphosphate + H2O = (2E,6E)-hedycaryol + diphosphate


name: cAMP dissociates PKA, promoting GLI processing (Rattus norvegicus)


name: chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity


name: Receptor CCR6 binds CCL20 ligand (Sus scrofa)


name: 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP


name: BLNK (SLP-65) Signalosome hydrolyzes phosphatidyinositol bisphosphate forming diacylglycerol and inositol-1,4,5-trisphosphate (Mus musculus)


name: 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphoethanolamine => N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: soppiline B + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = soppiline C + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: [protein]-C-terminal-L-glutamine + H2O = [protein]-C-terminal-L-glutamate + NH4(+)


name: CBL ubiquitinates FRS2 and FGFR4 (Xenopus tropicalis)


name: 3-oxochola-4,17-dien-22-oyl-CoA + AH2 => 3-oxochol-4-en-22-oyl-CoA + A


name: TFIIIA-class transcription factor binding


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Dictyostelium discoideum)


name: N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+) => adenosine(9) in tRNA + S-adenosyl-L-methionine


name: ITPA hydrolyses XTP to XMP (Schizosaccharomyces pombe)


name: succinate + NAD(+) <=> fumarate + NADH + H(+)


name: 4-aminobutanoyl-[BtrI ACP] + L-glutamate + ATP => 4-(gamma-L-glutamylamino)butanoyl-[BtrI ACP] + ADP + phosphate + H(+)


name: AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)


name: a tRNA precursor + 2 CTP + ATP = a tRNA with a 3' CCA end + 3 diphosphate


name: KLK5 cleaves and activates CELA2 (Homo sapiens)


name: N(6)-methyl-L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2 => N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2


name: oxidized Watasenia luciferin + hnu + CO2 => Watasenia luciferin + O2


name: N-(8'-oxogeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => N-(8'-hydroxygeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2


name: carboxy-S-adenosyl-L-methionine + 5-hydroxyuridine(34) in tRNA => 5-carboxymethoxyuridine(34) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47 (Bos taurus)


name: (S)-benzodiazepinedione + dimethylallyl diphosphate => (2S,3R,11S)-aszonalenin + diphosphate


name: PIN1 binds p-S345-NCF1 (Canis familiaris)


name: DNA ligase I ligates single stranded nick in double stranded DNA (Sus scrofa)


name: L-tryptophan <=> indole + 2-aminoprop-2-enoate


name: (E)-sinapoyl-CoA + D-glucono-1,5-lactone = 6-O-[(E)-sinapoyl]-D-glucono-1,5-lactone + CoA


name: The FA anion diffuses away laterally from UCP (Drosophila melanogaster)


name: AGRN binds Beta amyloid fibril via GAG chains (Mus musculus)


name: (5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoate + O2 <=> (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-eicosatetraenoate


name: chenodeoxycholate + NAD(+) => 3-oxochenodeoxycholate + NADH + H(+)


name: NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Homo sapiens)


name: Progesterone Activation Of CatSper (Canis familiaris)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Homo sapiens)


name: CUL3:RBX1 ubiquitinates KEAP1 (Gallus gallus)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG2 (Sus scrofa)


name: RAB31 GEFs exchange GTP for GDP on RAB31 (Sus scrofa)


name: tropine + NADP(+) => tropinone + NADPH + H(+)


name: 2-deoxy-D-glucose + ATP <=> 2-deoxy-D-glucose 6-phosphate + ADP + H(+)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Xenopus tropicalis)


name: phenylpropanonitrile + 2 H2O => 3-phenylpropanoate + NH4(+)


name: (3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD(+) + H2O => (R)-carnitine + NADH + O2 + H(+)


name: 2xLTBR binds LTBR:lymphotoxin,TNFSF14 trimer (Bos taurus)


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Gallus gallus)


name: p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Rattus norvegicus)