name: negative regulation of violaceol II biosynthetic process


name: 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 = 2 L-citrulline + 2 nitric oxide + NAD(+) + 2 H2O + H(+)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> fusoxypene B + diphosphate


name: DLST transfers succinyl to CoA (Dictyostelium discoideum)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 => (11S)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate


name: CYP2S1 4-hydroxylates atRA (Rattus norvegicus)


name: gibberellin A12 aldehyde + 2-oxoglutarate + O2 => gibberellin A12 + succinate + CO2 + H(+)


name: Formation of hydroxylysino-5-ketonorleucine cross-links (Homo sapiens)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and phosphorylated EGFR:ERBB2 heterodimers (Homo sapiens)


name: Keratin tetramers bind to form unit length filaments (Sus scrofa)


name: glutaryl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> (2E)-glutaconyl-CoA + reduced [electron-transfer flavoprotein]


name: 3 hydrogencarbonate(out) + Na(+)(out) = 3 hydrogencarbonate(in) + Na(+)(in)


name: ATP binding to HSP90 triggers conformation change (Canis familiaris)


name: (2E,11Z,14Z,17Z,20Z)-hexacosapentaenoyl-CoA + NADPH + H(+) <=> (11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + NADP(+)


name: Nuclear transport of pChREBP (Thr 666) protein (Sus scrofa)


name: Increased Brain Stem Epinephrine Activity


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + H2O <=> 1,3-di-(9Z,12Z)-octadecadienoylglycerol + (9Z,12Z)-octadecadienoate + H(+)


name: Exocytosis of secretory granule lumen proteins (Sus scrofa)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Saccharomyces cerevisiae)


name: 4-acetamidobutanoyl-CoA + H2O <=> 4-aminobutanoyl-CoA + acetate


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate => isopentenyl diphosphate + (2E,6E,10E)-geranylgeranyl diphosphate


name: (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine


name: (5Z,8Z,11Z)-eicosatrienoate + O2 <=> (12S)-hydroperoxy-(5Z,8Z,10E)-eicosatrienoate


name: 2 reduced [cytochrome P450] + NADP(+) + H(+) => 2 oxidized [cytochrome P450] + NADPH


name: ABCA12 transports lipids from cytosol to extracellular region (Drosophila melanogaster)


name: CYP17A1 17-hydroxylates P4 to 17aHPROG (Canis familiaris)


name: an alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose <=> an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)


name: Cyclin D:CDK4/6 mediated phosphorylation of p107 (RBL1) and dissociation of phosphorylated p107 (p-RBL1) from DP1:E2F4 complex (Sus scrofa)


name: CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADP(+) + H2O = CDP-4-dehydro-6-deoxy-alpha-D-glucose + NADPH + H(+)


name: PGE2 is converted to PGF2a by CBR1 (Canis familiaris)


name: LIPs hydrolyse TG to DAG and RCOOH (Sus scrofa)


name: L-lysine(out) + ATP + H2O = L-lysine(in) + ADP + phosphate + H(+)


name: AKT1 phosphorylates eNOS (Dictyostelium discoideum)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Homo sapiens)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Drosophila melanogaster)


name: USP48 cleaves polyubiquitin (Gallus gallus)


name: 28-nortyphasterol + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+) => 6-deoxo-28-nortyphasterol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2


name: kanamycin X + UDP + H(+) => 2'-deamino-2'-hydroxyparomamine + UDP-alpha-D-kanosamine


name: VAV2 is a GEF for Rho/Rac family kinases (Canis familiaris)


name: Clathrin recruits auxilins to the clathrin-coated vesicle (Gallus gallus)


name: Expression of CXCR4 in primordial germ cells (Homo sapiens)


name: uridine(747) in 23S rRNA + S-adenosyl-L-methionine => 5-methyluridine(747) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)


name: a 3-(omega-methylsulfanyl)alkylmalate = a 2-(omega-methylsulfanyl)alkylmaleate + H2O


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + (9Z)-octadecenoate + H(+)


name: 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP-alpha-D-glucose = 4-O-{[(2R)-2-alpha-D-glucosyl-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP + n H(+)


name: Receptors CXCR4 and 7 bind CXCL12 ligand (Danio rerio)


name: 8-oxo-dGTP + H2O => 8-oxo-dGDP + phosphate + H(+)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Plasmodium falciparum)


name: Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Drosophila melanogaster)


name: N(omega)-(1-hydroxy-2-oxopropyl)-L-arginyl-[protein] => L-arginyl-[protein] + methylglyoxal


name: ATP13A4,5 transport divalent ions from extracellular region to cytosol (Plasmodium falciparum)


name: Amyloid precursor proteins form ordered fibrils (Homo sapiens)


name: Defective SLC9A9 does not exchange Na+ for H+ across the late endosome membrane (Homo sapiens)


name: RHOF auto-activates (Drosophila melanogaster)


name: acetoacetate(out) + H(+)(out) => acetoacetate(in) + H(+)(in)


name: kallikrein:kininogen:C1q binding protein tetramer -> kallikrein + activated kininogen:C1q binding protein tetramer + bradykinin (Homo sapiens)


name: miR-200c-3p binds CDH11 mRNA (Homo sapiens)


name: RANBP2 SUMOylates RANBP2 with SUMO2 (Drosophila melanogaster)


name: N-acetyltaurine + H2O => taurine + acetate


name: (3E,5S)-3-[(2E,4E,8S,10E,12Z)-1-hydroxy-4,8-dimethyltetradeca-2,4,10,12-tetraen-1-ylidene]-5-[(4-hydroxyphenyl)methyl]pyrrolidine-2,4-dione + reduced [NADPH--hemoprotein reductase] + O2 => 3-[(2E,4E,8S,10E,12Z)-4,8-dimethyltetradeca-2,4,10,12-tetraenoyl]-4-hydroxy-5-(4-hydroxyphenyl)-1,2-dihydropyridin-2-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O


name: Autoglucosylation of GYG2 complexed with GYS2-b (Drosophila melanogaster)


name: CYP11B2 18-hydroxylates CORST to 18HCORST (Rattus norvegicus)


name: Sequestration of tBID by BCL-2 (Mus musculus)


name: ITPA hydrolyses dITP to dIMP (Homo sapiens)


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Drosophila melanogaster)


name: N-hexacosanoylglycine + H2O => hexacosanoate + glycine


name: Release of SEPT4 from mitochondria (Sus scrofa)


name: GTSE1 translocates to the nucleus (Gallus gallus)


name: 4-sulfobenzoate + NADH + 2 H(+) => 4-formylbenzenesulfonate + NAD(+) + H2O


name: ABC-type bacteriocin transporter activity


name: PTK6 phosphorylates KHDRBS1 (Xenopus tropicalis)


name: Anti-MET recombinant therapeutic antibodies bind MET (Danio rerio)


name: L-tryptophan + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 <=> (E)-(indol-3-yl)acetaldehyde oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)


name: Fatty acid ligands activate PPARA (Bos taurus)


name: dATP(in) + ATP(out) => dATP(out) + ATP(in)


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Rattus norvegicus)


name: PRKD1,2,3 phosphorylates CERT1-2 (Danio rerio)


name: KDM2A, KDM2B, KDM4A demethylate Me2K37-histone H3 (Homo sapiens)


name: L-histidine(out) + L-arginine(in) + Na(+)(out) = L-histidine(in) + L-arginine(out) + Na(+)(in)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Dictyostelium discoideum)


name: positive regulation of oxidoreductase activity


name: Autophosphorylation of PAK (Rattus norvegicus)


name: SARDH:FAD oxidatively demethylates SARC to Gly (Rattus norvegicus)


name: S100A7 or S100A7A binds Zn2+ (Bos taurus)


name: 1-methylimidazole-4-acetaldehyde + H2O2 + NH4(+) => N(tau)-methylhistamine + O2 + H2O


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + ATP


name: asperterpenoid A + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 => asperterpenoid B + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+)


name: DVL2 is phosphorylated by PKC (Homo sapiens)


name: 2-MAG is hydrolyzed to fatty acid and glycerol by MGLL (Canis familiaris)


name: EBP isomerizes ZYMSTNL to LTHSOL (Homo sapiens)


name: MDM2 forms homo- or heterodimers (Xenopus tropicalis)


name: Spontaneous hydrolysis of C3 thioester (Gallus gallus)


name: PICALM binds R-SNAREs (Rattus norvegicus)


name: ERBB4 binds NRGs or EGF-like ligands (Xenopus tropicalis)


name: Phospholipase C-gamma1 binds to the activated EGF receptor (Canis familiaris)


name: arginine + H2O => ornithine + urea [ARG2] (Sus scrofa)


name: Formation of N-glucuronides (Mus musculus)


name: biotin(in) + ATP + H2O = biotin(out) + ADP + phosphate + H(+)


name: L-arabinitol + NAD(+) <=> L-arabinose + NADH + H(+)


name: Glucagon binds to Glucagon receptor (Xenopus tropicalis)


name: Ubiquitination of NOTCH1 by ITCH in the absence of ligand (Homo sapiens)


name: selenodiglutathione-disulfide reductase (NADPH) activity


name: 2-propylphenol + NADH + O2 + H(+) <=> 3-propylcatechol + NAD(+) + H2O


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (8R)-hydroperoxy-(9E,11Z,14Z)-eicosatrienoate


name: TOPORS SUMOylates SIN3A with SUMO1 (Mus musculus)


name: AOX1 oxidises PXL to PDXate (Homo sapiens)


name: TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus (Sus scrofa)


name: (2R,3S)-beta-methylmalyl-CoA => 2-methylfumaryl-CoA + H2O


name: 5-hydroxyuridine(34) in tRNA + A + H2O => uridine(34) in tRNA + AH2 + O2


name: Methylation of GMP-cap by RNA Methyltransferase (Sus scrofa)


name: TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Homo sapiens)


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Xenopus tropicalis)


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + H2O <=> 1-O-alkyl-2-acyl-sn-glycerol + phosphate


name: The high affinity receptor complex binds to G-protein (Xenopus tropicalis)


name: beta-maaliene + diphosphate => (2E,6E)-farnesyl diphosphate


name: tetradecanoate + ATP + H(+) = tetradecanoyl-AMP + diphosphate


name: D-glucose + ADP => D-glucose 6-phosphate + AMP + H(+)


name: Activation of PAKs by RAC1 and CDC42 (Schizosaccharomyces pombe)


name: PIAS4 SUMOylates HERC2 with SUMO1 at DNA DSBs (Saccharomyces cerevisiae)


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) => 5alpha-androstan-3,17-dione + NADPH + H(+)


name: SUMOylation of DDX17 with SUMO1 (Caenorhabditis elegans)


name: L-tryptophan + dimethylallyl diphosphate <=> 7-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: L-phenylalanine + a fatty acid => an N-acyl-L-phenylalanine + H2O


name: oxidized 2[4Fe-4S]-[ferredoxin] + NADH => reduced 2[4Fe-4S]-[ferredoxin] + NAD(+) + H(+)


name: Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) (Homo sapiens)


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: HS3ST1 sulfates GlcN at C3 in heparan sulfate (Sus scrofa)


name: 4 L-ascorbate + O2 = 4 monodehydro-L-ascorbate radical + 2 H2O


name: PXLP-K754-GLDC dimer decarboxylates Gly (Dictyostelium discoideum)


name: (22E)-3-oxochola-4,22-dien-24-oyl-CoA + H2O = (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA


name: Spermidine  => N-acetylated spermidine (Rattus norvegicus)


name: neocasomorphin + H2O = neocasomorphin-(1-5) + L-isoleucine


name: CYSLT2 binds LTC4,LTD4,LTE4 (Canis familiaris)


name: (S)-3-methyl-2-oxopentanoate + H2O => (2R,3R)-2,3-dihydroxy-3-methylpentanoate


name: L-thyroxine sulfate(out) => L-thyroxine sulfate(in)


name: L-phenylalanine(out) + L-methionine(in) => L-phenylalanine(in) + L-methionine(out)


name: L-histidine(out) + L-tryptophan(in) => L-histidine(in) + L-tryptophan(out)


name: PAK1-3 dimer disassociates (Homo sapiens)


name: ITP(in) + CTP(out) => ITP(out) + CTP(in)


name: PRDM9 binds recombination hotspot motifs in DNA (Homo sapiens)


name: taurolithocholate + 3'-phosphoadenylyl sulfate = taurolithocholate 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Arachidonate is epoxidated to 11,12-EET by CYP(5) (Dictyostelium discoideum)


name: phosphatidylinositol + UDP-N-acetyl-D-glucosamine -> N-acetylglucosaminyl-PI + UDP (Sus scrofa)


name: 2-(acetamidomethylene)succinate + NAD(+) => 3-hydroxy-2-methylpyridine-5-carboxylate + NADH + O2


name: DOLK phosphorylates DCHOL to DOLP (Bos taurus)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Mus musculus)


name: DIS3L2 hydrolyzes uridylated mRNA (Homo sapiens)


name: SH2 domain of Src binds to the active receptor (Danio rerio)


name: UBA1 conjugates ubiquitin to UBA1 in the nucleus (Danio rerio)


name: MESP2 binds the EPHA4 gene (Homo sapiens)


name: HLCS biotinylates PC:Mn2+ (Drosophila melanogaster)


name: (E)-coniferol + acetyl-CoA => (E)-coniferyl acetate + CoA


name: MSH3 variant:MSH2-defective DNA mismatch repair (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Xenopus tropicalis)


name: MCAT transfers Mal from Mal-CoA to NDUFAB1 (Homo sapiens)


name: ANKH transports PPi from cytosol to extracellular region (Sus scrofa)


name: Activation of PLC beta-1/4 (Homo sapiens)


name: CHD1L is recruited to GG-NER site (Rattus norvegicus)


name: N-glycan glucose trimming of Spike (Homo sapiens)


name: Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Homo sapiens)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Bos taurus)


name: trans-zeatin-O-glucoside UDP glycosyltransferase activity


name: catechol + S-adenosyl-L-methionine => guaiacol + S-adenosyl-L-homocysteine + H(+)


name: activation of iron-sulfur electron transfer carrier


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Gallus gallus)


name: activation of IRE1alpha unfolded protein response


name: pyridine + H2O2 <=> pyridine N-oxide + H2O


name: (2E)-glutaconyl-CoA + Na(+)(in) + H(+) <=> (2E)-butenoyl-CoA + Na(+)(out) + CO2


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate


name: inhibition of FAS ligand-Fas signaling pathway


name: ATP + H2O + H(+)(in) => ADP + phosphate + 2 H(+)(out)


name: Tyrosine kinase Hopscotch (HOP) binds to the transmembrane cytokine receptor Domeless (DOME) to form the HOP:DOME complex (Drosophila melanogaster)


name: phlorisovalerophenone + 3 CO2 + 4 CoA => 3-methylbutanoyl-CoA + 3 malonyl-CoA + 3 H(+)


name: Activated FGFR4 phosphorylates SHC1 (Bos taurus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Homo sapiens)


name: Beclin-1 complex translocates to the ER (Mus musculus)


name: METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Homo sapiens)


name: GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress (Homo sapiens)


name: Thr-180 of ULK1 is phosphorylated (Canis familiaris)


name: PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Sus scrofa)


name: SARS-CoV-2 8 binds IL17RA (Homo sapiens)


name: sulfate + ADP + H(+) = adenosine 5'-phosphosulfate + phosphate


name: (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + H2O = (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + phosphate


name: RHOA:GTP translocates to the ER membrane (Xenopus tropicalis)