name: glycogen-glycogenin-2 + n orthophosphate => limit dextrin-glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Homo sapiens)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Canis familiaris)


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Mus musculus)


name: Mis18 complex binds the centromere (Rattus norvegicus)


name: 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Bos taurus)


name: Lysosomal degradation of gap junction plaques (Gallus gallus)


name: 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA is hydrated to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA (Bos taurus)


name: SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Mus musculus)


name: Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)


name: pentyl sulfate + 2-oxoglutarate + O2 = pentanal + sulfate + succinate + CO2 + H(+)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Homo sapiens)


name: LC3 de-lipidation by ATG4 (Dictyostelium discoideum)


name: butanoate + acetyl-CoA <=> butanoyl-CoA + acetate


name: CYP2C19 5-hydroxylates omeprazole (Drosophila melanogaster)


name: RAC2 GDIs block activation of RAC2 (Bos taurus)


name: beta-alanyl-tryptamine + AMP + diphosphate + H(+) => tryptamine + beta-alanine + ATP


name: menaquinol-13 + S-adenosyl-L-homocysteine + H(+) => 2-demethylmenaquinol-13 + S-adenosyl-L-methionine


name: 4-phosphooxy-L-aspartyl-tRNA(Asn) + NH4(+) => L-asparaginyl-tRNA(Asn) + phosphate + H(+)


name: 2-hydroxy-3-methoxy-estrone + S-adenosyl-L-homocysteine + H(+) => 2-hydroxyestrone + S-adenosyl-L-methionine


name: Translocation of activated BAD protein to mitochondria (Sus scrofa)


name: a 2,3-diacyl-sn-glycerol + a fatty acid + H(+) => a triacyl-sn-glycerol + H2O


name: N-ethylmaleimide + NADH + H(+) = N-ethylsuccinimide + NAD(+)


name: a tRNA with a 3' CC end + ATP <=> a tRNA with a 3' CCA end + diphosphate


name: PP5 dephosphorylates RAF1 S338 (Mus musculus)


name: Ag(+)(in) + ATP + H2O <=> Ag(+)(out) + ADP + phosphate + H(+)


name: p-T,Y MAPKs dimerize (Dictyostelium discoideum)


name: apigenin 4',7-dimethyl ether + reduced [NADPH--hemoprotein reductase] + O2 <=> ladanein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: DAG stimulates protein kinase C-delta (Caenorhabditis elegans)


name: CHEK2 phosphorylates BRCA1 (Mus musculus)


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Caenorhabditis elegans)


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 binds STAT3 and STAT5 (Sus scrofa)


name: (E)-alpha-bisabolene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: ACY3:Zn2+ dimer hydrolyses mercapturic acids (Xenopus tropicalis)


name: 2,4,6-trinitrotoluene + glutathione + AH2 = S-(2,4-dinitro-6-hydroxylaminotoluyl)glutathione + A + H2O


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Danio rerio)


name: AOX1 oxidises PXL to PDXate (Sus scrofa)


name: 2 putrescine <=> sym-homospermidine + NH4(+)


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Bos taurus)


name: down regulation of tyrosine phosphorylation of Stat7 protein


name: APSe is phosphorylated to PAPSe by PAPSS1,2 (Homo sapiens)


name: L-proline(in) + chloride(in) + 2 Na(+)(in) => L-proline(out) + chloride(out) + 2 Na(+)(out)


name: ST translocates from cytosol to mitochondrial matrix of hepatocytes (Homo sapiens)


name: Extracellular BTD hydrolyses BCTN (Danio rerio)


name: PANK4 hydrolyzes PPANT to pantetheine (Homo sapiens)


name: ATP4A:ATP4B binds PPIs (Canis familiaris)


name: (9Z,12Z)-octadecadienoate + ATP + CoA => (9Z,12Z)-octadecadienoyl-CoA + AMP + diphosphate


name: a jasmonyl-L-amino acid + reduced [NADPH--hemoprotein reductase] + O2 = a 12-hydroxyjasmonyl-L-alpha-amino acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Drosophila melanogaster)


name: PP2A mediated localization of RB1 protein in chromatin (Bos taurus)


name: P2Y4 receptor can bind to UTP (Mus musculus)


name: 3-oxo-(11Z)-hexadecenoyl-CoA + CO2 + CoA => (9Z)-tetradecenoyl-CoA + malonyl-CoA + H(+)


name: MAP1LC3B binds ATM dimer:Ub-p-PEX5:SQSTM1 (Mus musculus)


name: 12-(9Z-octadecenoyloxy)-octadecanoate + H2O <=> 12-hydroxyoctadecanoate + (9Z)-octadecenoate + H(+)


name: 3-dehydro-D-glucose 6-phosphate + L-glutamate <=> D-kanosamine 6-phosphate + 2-oxoglutarate


name: ferric-chelate reductase (NADH) activity


name: OPN (osteopontin) degradation by MMP3, MMP7 (Canis familiaris)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Mus musculus)


name: EDNRA, EDNRB bind non-selective ERAs (Gallus gallus)


name: FN3KRP phosphorylates PsiAm, RibAm (Mus musculus)


name: ANOs transport cytosolic Cl- to extracellular region (Bos taurus)


name: 3-(all-trans-heptaprenyl)benzene-1,2-diol + NADP(+) + H2O => 2-all-trans-heptaprenylphenol + NADPH + O2 + H(+)


name: activation of [phosphotyrosine]protein phosphatase activity


name: PELI1 ubiquitinates RIPK3 at K363 (Canis familiaris)


name: Expression of GBX2 in the neural plate border (Homo sapiens)


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Dictyostelium discoideum)


name: Beta-catenin translocates to the nucleus (Canis familiaris)


name: L-leucine + acetyl-CoA => N-acetyl-L-leucine + CoA + H(+)


name: IMP + H2O <=> hypoxanthine + D-ribose 5-phosphate


name: PXLP-K333-GADL1 decarboxylates acidic AAs (Homo sapiens)


name: LMAN family proteins bind glycosylated cargo (Canis familiaris)


name: GTP + AH2 + S-adenosyl-L-methionine <=> (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)


name: RHOD translocates to the mitochondrial outer membrane (Canis familiaris)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Dictyostelium discoideum)


name: SIRT4 cleaves lipoyl from DLAT (Drosophila melanogaster)


name: a 1,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine => a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Defective ALG8 does not add glucose to the N-glycan precursor (Homo sapiens)


name: 3,6-dichlorocatechol + O2 <=> (2E,4E)-2,5-dichloromuconate + H(+)


name: 3-O-{N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + 3'-phosphoadenylyl sulfate <=> 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: 3'-dehydrocarminate + H(+) <=> kermesate + 1,5-anhydro-D-erythro-hex-1-en-3-ulose


name: P2Y6 receptor can bind to UDP (Homo sapiens)


name: BTNL8 binds resting T cell surface (Gallus gallus)


name: (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => (5S)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Danio rerio)


name: 9alpha-copalyl diphosphate => syn-isopimara-7,15-diene + diphosphate


name: SEPT7 binds p-S189 MAPK6 and p-T182 MAPKAPK5 (Rattus norvegicus)


name: phytyl diphosphate + chlorophyllide a + H(+) => chlorophyll a + diphosphate


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + ADP + H(+) => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP


name: ISGylation of host protein filamin B (Caenorhabditis elegans)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Drosophila melanogaster)


name: PXLP-K280-SHMT2 tetramer transfers CH2OH group to Gly to form L-Ser (Plasmodium falciparum)


name: L-histidine(in) + chloride(in) + 2 Na(+)(in) => L-histidine(out) + chloride(out) + 2 Na(+)(out)


name: 1-O-methyl-8-hydroperoxy-20-hydroxy-(5Z,9E,11Z,14Z)-eicosatetraenoate => 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: L-threonyl-[protein] + octanoyl-CoA => O-octanoyl-L-threonyl-[protein] + CoA


name: Cohesin binds PDS5 and WAPAL (Gallus gallus)


name: YAP1 binds ZO-2 (TJP2) (Rattus norvegicus)


name: PRC1 SUMOylates CTBP1 with SUMO1 (Xenopus tropicalis)


name: 3-dimethylallyl-4-hydroxymandelate + O2 => 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O


name: NEIL3 recognizes and binds to spiroiminodihydantoin in telomeric DNA (Homo sapiens)


name: cis-aconitate(out) + citrate(in) => cis-aconitate(in) + citrate(out)


name: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate => D-erythrose 4-phosphate + phosphoenolpyruvate + H2O


name: down regulation of FAS ligand-Fas signaling pathway


name: Cleavage of ethenoadenine by MPG glycosylase (Canis familiaris)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Rattus norvegicus)


name: N,N-dimethyl-1,4-phenylenediamine + anthranilate + 2 NAD(+) <=> 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 NADH + 2 H(+)


name: (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose => glucoerucin + H2O


name: 2-methylcitrate => 2-methyl-cis-aconitate + H2O


name: PEX-19 docks ABCD1/D2/D3 to peroximal membrane (Sus scrofa)


name: Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Bos taurus)


name: 7alpha,12alpha-dihydroxy-3-oxo-5beta-cholan-24-oate + NADH + H(+) => isocholate + NAD(+)


name: L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2


name: RHOF binds effectors at the plasma membrane (Homo sapiens)


name: ASAP1 dimer binds membrane proteins (Homo sapiens)


name: RAS guanyl nucleotide exchange mediated by SOS1 bound to GRB2 in complex with phosphorylated ERBB4:ERBB2 heterodimers (Gallus gallus)


name: 2-cis-(+)-abscisic aldehyde + O2 + H2O => 2-cis-(+)-abscisate + H2O2 + H(+)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Schizosaccharomyces pombe)


name: Collagen type III degradation by MMP14 (Rattus norvegicus)


name: chloroeremomycin + dTDP + H(+) => chloroorienticin B + dTDP-beta-L-vancosamine


name: epitestosterone + NADPH + H(+) <=> 5beta-dihydroepitestosterone + NADP(+)


name: TGFBR2 phosphorylates TGFBR1 (Danio rerio)


name: phosphonate + NAD(+) + H2O <=> phosphate + NADH + H(+)


name: retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification


name: Cho transports from the extracellular space to the cytosol (Canis familiaris)


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Canis familiaris)


name: Nectin-2:Nectin 3 trans heterodimer interaction (Rattus norvegicus)


name: gamma-L-glutamyl-L-cysteine + beta-alanine + ATP <=> gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + phosphate + H(+)


name: RAC1 binds effectors at the ER membrane (Bos taurus)


name: (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF1A (Homo sapiens)


name: propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+)


name: USP8 deubiquitinates LRIG1 (Gallus gallus)


name: brevianamide F + 2 AMP + 2 diphosphate + 2 H(+) => L-proline + L-tryptophan + 2 ATP


name: D-loop extension by DNA polymerases (Homo sapiens)


name: B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda (Bos taurus)


name: P4HB:4-Hyp collagen propeptides dissociates (Mus musculus)


name: a thymidine in DNA + S-methyl-L-cysteinyl-[protein] => a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein]


name: 24,25-dihydrolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 32-hydroxy-24,25-dihydrolanosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA = 1-octanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: ASPA deacetylates NAASP to acetate and L-aspartate (Danio rerio)


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Drosophila melanogaster)


name: androsterone + NADPH + H(+) => 5alpha-androstane-3alpha,17beta-diol + NADP(+)


name: holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + S-adenosyl-L-methionine + 11 NADPH + 19 H(+) <=> dihydromonacolin L-[lovastatin nonaketide synthase] + S-adenosyl-L-homocysteine + 9 CO2 + 11 NADP(+) + 9 CoA + 6 H2O


name: pyridoxal + NADH + H(+) => pyridoxine + NAD(+)


name: HLCS biotinylates 6xMCCC1:6xMCCC2 (Homo sapiens)


name: MMADHC targets transport of cytosolic cob(II)alamin to mitochondria (Caenorhabditis elegans)


name: Exocytosis of Proactivator polypeptide (Danio rerio)


name: LIPs hydrolyze TG to DAG and LCFA (Saccharomyces cerevisiae)


name: Release of Cytochrome c from mitochondria (Rattus norvegicus)


name: 5-taurinomethyl-2-thiouridine(34) in tRNA + L-cysteinyl-[protein] + A + AMP + diphosphate + H(+) => 5-taurinomethyluridine(34) in tRNA + S-sulfanyl-L-cysteinyl-[protein] + AH2 + ATP


name: 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: inhibition of estriol UDPglucuronosyltransferase activity


name: stevioside glucosyltransferase activity (rebaudioside A forming)


name: Association of DNA-PKcs with Ku-bound ends of DNA double-strand breaks - synapsis (Dictyostelium discoideum)


name: ME2 tetramer decarboxylates MAL to PYR (Danio rerio)


name: positive regulation of polynucleotide 3'-phosphatase activity


name: D-serine(out) + H(+)(out) => D-serine(in) + H(+)(in)


name: PIAS4 SUMOylates HERC2 with SUMO1 (Gallus gallus)


name: MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Sus scrofa)


name: DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Rattus norvegicus)


name: ABO-A:Mn2+ transfers GalNAc to H antigen-RBC to form A antigen-RBC (Xenopus tropicalis)


name: Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Gallus gallus)


name: N-acetyl-alpha-D-hexosamine 1-phosphate + ADP + H(+) => N-acetyl-D-hexosamine + ATP


name: 1-naphthaldehyde + O2 + H2O => 1-naphthoate + H2O2 + H(+)


name: 2,2-dihydroxyspheroidene = spheroiden-2-one + H2O


name: MAN2B2 hydrolyses GlcNAc (Man)3 to GlcNAc:Man (Xenopus tropicalis)


name: ubiquinone-8 + NADH + 5 H(+)(in) => ubiquinol-8 + NAD(+) + 4 H(+)(out)


name: TGFBR3_mem cleavage by MMPs (Sus scrofa)


name: ajmalicine + reduced [NADPH--hemoprotein reductase] + O2 = dihydroserpentine + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Caenorhabditis elegans)


name: a ganglioside GM3 (d18:1(4E)) + N-acetylneuraminate => a ganglioside GD3 (d18:1(4E)) + H2O


name: Homodimerization of VEGF proteins (Danio rerio)


name: glyoxylate + NADP(+) + CoA = oxalyl-CoA + NADPH + H(+)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Sus scrofa)


name: (20S)-ginsenoside Rh2 + UDP-alpha-D-glucose => (20S)-ginsenoside F2 + UDP + H(+)


name: positive regulation of glucuronosyltransferase activity


name: Trimming of mannoses on the alpha1,6 arm by MAN2A1 (Drosophila melanogaster)


name: PXLP-K198-NFS1 transfers sulfur from cysteine onto MOCS3 (Homo sapiens)


name: dTTP + H2O <=> dTMP + diphosphate + H(+)


name: N-(tetradecanoyl)-sphinganine + CoA + H(+) => sphinganine + tetradecanoyl-CoA


name: beta-catenin/T-cell factor complex assembly


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate = 13-oxo-(9Z,11E)-octadecadienoate + H2O


name: [thioredoxin]-dithiol + ADP => dADP + [thioredoxin]-disulfide + H2O


name: dATP + pyruvate => dADP + phosphoenolpyruvate + H(+)


name: hydrogen sulfide + pyruvate + NH4(+) + H(+) => D-cysteine + H2O


name: Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) (Canis familiaris)


name: 5-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 5,20-dihydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: depalmitoylated eNOS translocates from plasma membrane (Schizosaccharomyces pombe)


name: 8-amino-8-demethylriboflavin + 2 S-adenosyl-L-methionine <=> roseoflavin + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => a 1,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine


name: 4-(3-methylbut-2-enyl)-L-tryptophan + diphosphate => L-tryptophan + dimethylallyl diphosphate


name: WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Canis familiaris)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Drosophila melanogaster)


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Mus musculus)


name: oxoglutarate dehydrogenase (NAD+) activity


name: L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP-L-glycero-beta-D-manno-heptose <=> L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP + H(+)


name: L-cysteinyl-5'-AMP + holo-[peptidyl-carrier protein] <=> L-cysteinyl-[peptidyl-carrier protein] + AMP + H(+)


name: dodecanoyl-[ACP] + malonyl-[ACP] + H(+) => 3-oxotetradecanoyl-[ACP] + holo-[ACP] + CO2


name: Defective CYP11B2 does not oxidise CORST (Homo sapiens)


name: CASP8 cleaves N4BP1 at D424, D490 (Danio rerio)


name: 9-cis-10'-apo-beta-carotenal + 2 O2 = (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactone


name: hapalindole U + chloride + 2-oxoglutarate + O2 + H(+) = hapalindole G + succinate + CO2 + H2O


name: SUMOylation of DNMT3B with SUMO1 (Rattus norvegicus)


name: a 3-oxo bile acid CoA + NADH + H(+) => a 3alpha-hydroxy bile acid CoA + NAD(+)


name: PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Saccharomyces cerevisiae)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Canis familiaris)


name: L-2-aminoadipate(in) + 2-oxoglutarate(out) => L-2-aminoadipate(out) + 2-oxoglutarate(in)


name: CL-LK binds carbohydrates on target cell surface (Gallus gallus)


name: phosphoenolpyruvate + GTP + H(+) <=> enolpyruvoyl-2-diphospho-5'-guanosine + diphosphate


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Rattus norvegicus)


name: inhibition of nonadec-1-ene metabolic process


name: N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6R)-10-formyltetrahydrofolate <=> N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + (6S)-5,6,7,8-tetrahydrofolate + H(+)


name: 3-(4-hydroxyphenyl)propionic acid methyl ether + S-adenosyl-L-homocysteine => phloretate + S-adenosyl-L-methionine


name: all-trans-nonaprenyl diphosphate + 4-hydroxybenzoate => 4-hydroxy-3-all-trans-nonaprenylbenzoate + diphosphate


name: cholesterol + reduced [NADPH--hemoprotein reductase] + O2 <=> 7alpha-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: cholate + ATP + CoA = choloyl-CoA + AMP + diphosphate


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Drosophila melanogaster)


name: O-demethylpuromycin + S-adenosyl-L-methionine <=> puromycin + S-adenosyl-L-homocysteine + H(+)


name: negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: SHC1 phosphorylation by ERBB2 heterodimers (Xenopus tropicalis)


name: DHCR24 reduces LAN to 24,25-dhLAN (Caenorhabditis elegans)


name: D-ribonate <=> 2-dehydro-3-deoxy-D-arabinonate + H2O


name: NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Rattus norvegicus)


name: taurodeoxycholate + H2O <=> deoxycholate + taurine


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + UDP + H(+) => 3-O-(N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine


name: an alcohol + methylamine + CO2 => an N-methyl carbamate ester + H2O + H(+)


name: a 5'-end guanosine-5'-diphospho-5'-(2'-deoxyribonucleoside)-DNA + H2O <=> a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + GMP + 2 H(+)


name: 3-phenyllactate + NADP(+) <=> 3-phenylpyruvate + NADPH + H(+)


name: adenosine 2',5'-bisphosphate + H2O = AMP + phosphate


name: Fibulin-1 and -2 bind fibronectin (Canis familiaris)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Caenorhabditis elegans)


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Homo sapiens)


name: Ubiquitination of stimulated EGFR (CBL) (Caenorhabditis elegans)


name: PSMC2 binds PSMC1 (Drosophila melanogaster)


name: RAC2 binds effectors at the phagocytic vesicle membrane (Gallus gallus)


name: plus-end directed microfilament motor activity


name: holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Mus musculus)


name: PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Mus musculus)


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Canis familiaris)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Homo sapiens)


name: ERBB2 promotes PTK6 autophosphorylation (Danio rerio)


name: LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Sus scrofa)


name: D-glucose 6-phosphate => 2-deoxy-L-scyllo-inosose + phosphate


name: Delta(1)-piperideine-2-carboxylate + NH4(+) + NADH + H(+) => L-lysine + NAD(+)


name: dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 3-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (6E)-8-hydroxygeranial + NADPH + H(+) => (6E)-8-hydroxygeraniol + NADP(+)


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide


name: POMGNT1 transfers GlcNAc from UDP-GlcNAc to Man-O-Ser-DAG1 (Bos taurus)


name: Phosphorylation of Cyclin A:Cdk2 at Tyr 15 (Canis familiaris)


name: Increased Cerebral Cortex Dynorphin Activity


name: positive regulation of hexokinase type I activity


name: APC/C:Cdh1-mediated degradation of Skp2 (Canis familiaris)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Canis familiaris)


name: USP7 deubiquitinates TP53 and counteracts MDM2 (Drosophila melanogaster)


name: Secretion of transmembrane collagens (Mus musculus)


name: CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Dictyostelium discoideum)


name: EHMT1:EHMT2 methylates IL6 promoter (Bos taurus)


name: 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-alpha-D-galactose => 3-O-(beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-L-Fuc)-L-threonyl-[EGF-like domain protein] + UDP + H(+)


name: MAT1A multimers transfer Ado from ATP to L-Met (Dictyostelium discoideum)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Danio rerio)


name: Some HSPGs are secreted to the plasma membrane (Xenopus tropicalis)


name: an aldehyde + NADP(+) + H2O = a carboxylate + NADPH + 2 H(+)


name: 4-hydroxy-6-(2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA => octadecanoyl-CoA + 3 malonyl-CoA + 3 H(+)


name: 1-heptadecanoyl-sn-glycero-3-phosphate + hexadecanoyl-CoA => 1-heptadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA


name: ERBB2 TMD/JMD mutants hetrodimerize (Homo sapiens)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Rattus norvegicus)


name: GLUT7 and GLUT11 transport glucose and fructose (Bos taurus)


name: Noradrenaline is converted to adrenaline (Mus musculus)


name: Caspase-6 translocates to the nucleus (Sus scrofa)


name: an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontadienoyl)-sphing-4-enine + a diacylglycerol => an N-(36-hydroxyhexatriacontadienoyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Drosophila melanogaster)


name: inhibition of alkane biosynthetic process


name: a monocarboxylate + NH4(+) => a monocarboxylic acid amide + H2O


name: 1,4-benzoquinone + nitrite + NADP(+) + H2O => 4-nitrophenol + NADPH + O2 + H(+)


name: (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + glutathione disulfide + H2O


name: NFE2L2-dependent TALDO1 gene expression (Homo sapiens)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Canis familiaris)


name: FN1 binds Collagen types I-V, VII (Bos taurus)


name: ABHD3 hydrolyses LPC(14:0) to 1AGPC (Canis familiaris)


name: 1-eicosanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => eicosanoyl-CoA + 2-(9Z-octadecenoyl)-glycerol


name: 2-hydroxy-3-methoxy-17beta-estradiol + S-adenosyl-L-homocysteine + H(+) => 2-hydroxy-17beta-estradiol + S-adenosyl-L-methionine


name: AURKA phosphorylates PHLDA1 (Sus scrofa)


name: SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Sus scrofa)


name: NEXT2 is cleaved to produce NICD2 (Homo sapiens)


name: 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate](n) + adenosine 3',5'-bisphosphate + H(+) => alpha-D-glucosaminyl-[heparan sulfate](n) + 3'-phosphoadenylyl sulfate


name: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate => UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate


name: PRKG is activated by binding to high levels of cGMP in the absence of WNT signaling (Homo sapiens)


name: AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Canis familiaris)


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)


name: Reactive oxygen species oxidize DNAJA1 (Plasmodium falciparum)


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Xenopus tropicalis)


name: Association of procollagen type XIX (Mus musculus)


name: STAMBPL1 is a deubiquitinase (Rattus norvegicus)


name: protein phosphatase 3 regulator activity


name: ANOs transport cytosolic Cl- to extracellular region (Xenopus tropicalis)


name: L-cysteine(out) + L-arginine(in) => L-cysteine(in) + L-arginine(out)


name: AOX1 oxidises PXL to PDXate (Xenopus tropicalis)


name: (R)-pantothenate + ADP + phosphate + H(+) => (R)-pantoate + beta-alanine + ATP


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Homo sapiens)


name: ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link) (Danio rerio)


name: OPTN binds TBK1 within the activated TLR4 complex (Rattus norvegicus)


name: 3-oxoisoapionate 4-phosphate + H(+) = L-erythrulose 1-phosphate + CO2


name: N,N-dimethyl-1,4-phenylenediamine + anthranilate + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 NADH + 2 H(+)


name: (2R,3S)-piscidate + (E)-sinapoyl-CoA = cimicifugate J + CoA


name: Recruitment of SET1 methyltransferase complex (Drosophila melanogaster)


name: CTDNEP1:CNEP1R1 dephosphorylates LPIN (Bos taurus)


name: TNFSF11 binds TNFRSF11A, B (Homo sapiens)


name: CAMK2 binds MAP3K7 (Drosophila melanogaster)


name: Collagen type XXV ectomain shedding (Gallus gallus)


name: RNA demethylases demethylate N6-methyladenosine RNA (Rattus norvegicus)


name: Syk activation leads to SLP-76 activation (Xenopus tropicalis)


name: p-4Y-PLCG1 dissociates from activated FGFR3 (Bos taurus)


name: 4-methyl-cyclohexylamine + NADP(+) + H2O => 4-methylcyclohexanone + NH4(+) + NADPH + H(+)


name: UBF-1 Binds rDNA Promoter (Rattus norvegicus)


name: N-dodecanoyl-3-oxosphinganine + CoA + H(+) => 3-oxosphinganine + dodecanoyl-CoA


name: ent-kaur-16-en-19-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => ent-kaur-16-ene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Rattus norvegicus)


name: ADP + ADP <=> AMP + ATP [AK2] (Schizosaccharomyces pombe)


name: DLD dimer dehydrogenates dihydrolipoyl (Bos taurus)


name: RETN gene expression is stimulated by FOXO1 (Homo sapiens)


name: LIG1 binds POLB at long-patch BER site (Canis familiaris)


name: D-lysine + O2 + H2O <=> 6-amino-2-oxohexanoate + H2O2 + NH4(+)


name: UMP(out) + CMP-N-acetyl-beta-neuraminate(in) => UMP(in) + CMP-N-acetyl-beta-neuraminate(out)


name: cysteine-type endopeptidase activator activity


name: 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + phosphate + 2 H2O => 2 D-glyceraldehyde 3-phosphate


name: SHMT1 tetramer cleaves HTMLYS to yield TEABL and Gly (Plasmodium falciparum)


name: N(4)-acetylcytidine + ATP <=> N(4)-acetylcytidine 5'-phosphate + ADP + H(+)


name: a 5-hydroxymethyl-2'-deoxycytidine in DNA + 2-oxoglutarate + O2 <=> a 5-formyl-2'-deoxycytidine in DNA + succinate + CO2 + H2O


name: putrescine + 2-oxoglutarate => 4-aminobutanal + L-glutamate


name: FUCA1 hydrolyses NGP:1,6-GlcNAc (Caenorhabditis elegans)


name: Monoubiquitinated PTEN translocates to the nucleus (Homo sapiens)


name: USP13 deubiquitinates BECN1,USP10 (Sus scrofa)


name: Nucleotide exchange on RAB1 (Saccharomyces cerevisiae)


name: CDC42 translocates to the endoplasmic reticulum membrane (Sus scrofa)


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Homo sapiens)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + 3'-phosphoadenylyl sulfate => 1,2-diacyl-3-(3-O-sulfo-beta-D-galactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+)


name: Collagen type VII degradation by MMP1,2,3 (Caenorhabditis elegans)


name: ATPase-coupled monoatomic cation transmembrane transporter activity


name: MDC1 associates with gamma-H2AFX at nuclear foci (Rattus norvegicus)


name: 1,4-dihydroxy-6-naphthoate + all-trans-octaprenyl diphosphate + H(+) <=> 2-demethylmenaquinol-8 + CO2 + diphosphate


name: RHOA:GTP binds RHPN1 or RHPN2 (Bos taurus)


name: taurine + A + H2O <=> sulfoacetaldehyde + AH2 + NH4(+)


name: 5beta-scymnol + 3'-phosphoadenylyl sulfate => 5beta-scymnol sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Active calmodulin binds CAMK2 (Drosophila melanogaster)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Saccharomyces cerevisiae)


name: (+)-larreatricin + AH2 + O2 <=> (+)-3'-hydroxylarreatricin + A + H2O


name: Alpha-2A,alpha-2C Adrenergic Receptors bind adrenaline or noradrenaline (Mus musculus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H(+)


name: acetoacetyl-CoA+acetyl-CoA => HMG-CoA + CoASH (Sus scrofa)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Gallus gallus)


name: L-mannopyranose(in) + H(+)(in) => L-mannopyranose(out) + H(+)(out)


name: ALOX5 dehydrogenates 4(S)-Hp-17(R)-HDHA to 4S(5)-epoxy-17(R)-HDHA (Canis familiaris)


name: Conversion of C2 into C2a and C2b (Gallus gallus)


name: CBL-mediated ubiquitination of CIN85 (Mus musculus)


name: 4-sulfobenzoate + NADH + O2 <=> 3,4-dihydroxybenzoate + sulfite + NAD(+)


name: furfural + NAD(+) + H2O <=> 2-furoate + NADH + 2 H(+)


name: lipid IVA (E. coli) + a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine = lipid IVB (E. coli) + a 2-acyl-sn-glycero-3-phosphocholine


name: Phosphorylation of Chk1 by ATR (Gallus gallus)


name: 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+) => myo-inositol + S-adenosyl-L-methionine


name: SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Canis familiaris)


name: pyruvate + NADP(+) + CoA => acetyl-CoA + CO2 + NADPH


name: Formation of Activated Protein 1 (AP-1) complex. cFOS/c-JUN heterodimer.  (Rattus norvegicus)


name: CUL3:RBX1 ubiquitinates KEAP1 (Mus musculus)


name: umbelliferone + dimethylallyl diphosphate => osthenol + diphosphate


name: GDP-alpha-D-glucose + H2O => alpha-D-glucose 1-phosphate + GMP + 2 H(+)


name: Caspase-mediated cleavage of Acinus (Rattus norvegicus)


name: activation of monocluster bacterial-type ferredoxin


name: propane + NADH + O2 + H(+) => propan-2-ol + NAD(+) + H2O


name: MEMO1 binds RHOA:GTP:DIAPH1 (Drosophila melanogaster)


name: p-STAT1 and p-STAT3 dissociates from IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 (Canis familiaris)


name: mycinamicin III + S-adenosyl-L-methionine <=> mycinamicin IV + S-adenosyl-L-homocysteine + H(+)


name: adenylate cyclase-activating G protein-coupled receptor signaling pathway


name: cob(II)yrinate + L-glutamine + ATP + H2O <=> cob(II)yrinate c monoamide + L-glutamate + ADP + phosphate + H(+)


name: NEIL1,NEIL2 displace OGG1 from AP-dsDNA (Canis familiaris)


name: a percarboxylic acid + H2O <=> a carboxylate + H2O2 + H(+)


name: a beta-D-glucosylceramide(out) + ADP + phosphate + H(+) => a beta-D-glucosylceramide(in) + ATP + H2O


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Sus scrofa)


name: EGFR phosphorylates EPS15 (Drosophila melanogaster)


name: 2 Fe(2+) + H2O2 + 2 H2O => 2 iron(III) oxide-hydroxide + 6 H(+)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+) => beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-alpha-D-GalNAc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-beta-L-fucose


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Homo sapiens)


name: Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Xenopus tropicalis)


name: gramine + 2 S-adenosyl-L-homocysteine + 2 H(+) => 3-(aminomethyl)indole + 2 S-adenosyl-L-methionine


name: pyruvate(out) + Na(+)(out) <=> pyruvate(in) + Na(+)(in)


name: N-hexadecanoyl-serotonin + CoA + H(+) => serotonin + hexadecanoyl-CoA


name: a very long-chain fatty acid(in) + ATP + H2O => a very long-chain fatty acid(out) + ADP + phosphate + H(+)


name: HCO3- transport through ion channel (Bos taurus)


name: cyclohexan-1,2-dione + H2O => 6-oxohexanoate + H(+)


name: N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+) => L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Sus scrofa)


name: KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) (Homo sapiens)


name: PNPLA4 hydrolyzes retinyl palmitate (Canis familiaris)


name: 5-(9Z-octadecenoyloxy)-octadecanoate + H2O <=> 5-hydroxy-octadecanoate + (9Z)-octadecenoate + H(+)


name: CDP-choline + a 1,2-diacyl-sn-glycerol <=> a 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: ASP-3026- resistant ALK mutants don't bind ASP-3026 (Homo sapiens)


name: HNMT transfers CH3 group from AdoMet to Hist (Homo sapiens)


name: CYP1B1 4-hydroxylates EST17b (Homo sapiens)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Dictyostelium discoideum)


name: MAPK4,6 translocate to nucleus (Schizosaccharomyces pombe)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Mus musculus)


name: Defective LCT does not hydrolyze Lac (Homo sapiens)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Bos taurus)


name: MIB2 ubiquitinates CYLD at K338, K530 (Bos taurus)


name: kaempferol 3-O-beta-D-glucoside + H2O <=> kaempferol + beta-D-glucose


name: Recruitment of PLC-gamma1 to SLP-76 (Canis familiaris)


name: PTPN12 dephosphorylates ERBB2 on tyrosine Y1248 (Homo sapiens)


name: LFT binds to FT and DS (Drosophila melanogaster)


name: glutamate catabolic process to fumarate, using glutamate synthase (NADPH)


name: L-phenylalanine(out) + glycine(in) <=> L-phenylalanine(in) + glycine(out)


name: (2E)-geranial + NAD(+) + H2O = geranate + NADH + 2 H(+)


name: NPM1 binds TFAP2A homodimer (Canis familiaris)


name: testosterone + A => androst-4-ene-3,17-dione + AH2


name: an S-(2-hydroxyacyl)glutathione + H2O => a 2-hydroxy carboxylate + glutathione + H(+)


name: Activated protein C cleaves factor Va to factor Vi intermediate form (Danio rerio)


name: galactitol 1-phosphate(in) + L-histidyl-[protein] => galactitol(out) + N(pros)-phospho-L-histidyl-[protein]


name: 1,6-dihydroxyphenazine + NADPH + O2 <=> 1,6-dihydroxyphenazine N(5)-oxide + NADP(+) + H2O


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Schizosaccharomyces pombe)


name: OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA (Xenopus tropicalis)


name: ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Rattus norvegicus)


name: CYP26A1,B1,C1 4-hydroxylate atRA (Xenopus tropicalis)


name: a 2'-deoxyguanosine in DNA + glyoxal = an N(2)-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA


name: oleanolate + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 => gypsogenate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: ADPRM hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)


name: L-methionine + H(+) => 3-(methylsulfanyl)propanamine + CO2


name: 4-guanidinobutanal + CO2 => 5-guanidino-2-oxopentanoate + H(+)


name: a plastoquinone + L-arginine + H2O => a plastoquinol + 5-guanidino-2-oxopentanoate + NH4(+)


name: an N-acyl-1-beta-D-(3-O-sulfo)-galactosyl-sphing-4-enine + H2O = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine + sulfate + H(+)


name: cortisone + NAD(+) <=> 17alpha-hydroxypregn-4-en-3,11,20-trione-21-al + NADH + H(+)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Gallus gallus)


name: Budding of COPII coated vesicle (Bos taurus)


name: MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin (Canis familiaris)


name: 3beta-hydroxy-5alpha-androstan-17-one + reduced [NADPH--hemoprotein reductase] + O2 => 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: RHOC activates endoplasmic reticulum effectors (Mus musculus)


name: PSMD9 binds PSMC3:PSMC6 (Dictyostelium discoideum)


name: Endonucleolytic RISC hydrolyzes target RNAs (Gallus gallus)


name: oligopeptide transmembrane transporter activity


name: Phosphorylation of beta and gamma subunits by LYN (Rattus norvegicus)


name: an oxoeicosatetraenoate + H2O => a hydroperoxyeicosatetraenoate


name: Aquaporin-1 passively transports water into cell (Drosophila melanogaster)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + phosphate


name: Calmodulin activates Cam-PDE 1 (Caenorhabditis elegans)


name: PSMG3 binds PSMG4 (Dictyostelium discoideum)


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Mus musculus)


name: L-glutamyl-[peptidyl-carrier protein] + AMP + H(+) => L-glutamyl-5'-AMP + holo-[peptidyl-carrier protein]


name: TYRP1 oxidises DHICA to IQCA (Bos taurus)


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP = 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+)


name: N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-lipoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Homo sapiens)


name: a thymidine(6-4)thymidine in DNA => a thymidine dimer in DNA


name: HSD17B4 dehydrogenates 3-hydroxyhexacosanoyl-CoA (Mus musculus)


name: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Drosophila melanogaster)


name: (20S)-ginsenoside C-K + UDP-alpha-D-glucose => (20S)-ginsenoside F2 + UDP + H(+)


name: abieta-7,13-dien-18-ol + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 <=> abieta-7,13-dien-18-oate + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+)


name: Importin-8 imports AGO2:miRNA into the nucleus (Homo sapiens)


name: a sterol + UDP-alpha-D-glucose => a sterol 3-beta-D-glucoside + UDP + H(+)


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Canis familiaris)


name: IL10 dimer:2xIL10RA1:JAK1 binds IL10RB:TYK2 (Sus scrofa)


name: SQR oxidizes sulfide to bound persulfide (Homo sapiens)


name: (2E)-triacontenoyl-CoA + NADPH + H(+) <=> triacontanoyl-CoA + NADP(+)


name: CCR4-NOT complex deadenylates mRNA (Bos taurus)


name: (2E,6E)-farnesyl diphosphate + H2O = 10-epi-gamma-eudesmol + diphosphate


name: Arachidonate is oxidised to 15S-HpETE by ALOX15/15B (Canis familiaris)


name: PTPS is phosphorylated by cGMP-dependant protein kinase II (Homo sapiens)


name: NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Homo sapiens)


name: p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Gallus gallus)


name: GRKs bind ADRB2:Catecholamine (Canis familiaris)


name: SHP1 and SHP2 dephosphorylate Y628 of IL3RB (Mus musculus)


name: L-phenylalanine(in) + L-methionine(out) => L-phenylalanine(out) + L-methionine(in)


name: apo-L-cysteinyl(84)-[allophycocyanin beta-subunit] + (2R,3E)-phycocyanobilin => phycocyanobilin-L-cysteinyl(84)-[allophycocyanin beta-subunit]


name: Nuclear CRY is degraded by the 26S proteasome (Drosophila melanogaster)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O


name: sinigrin + H2O = (Z)-N-(sulfonatooxy)prop-2-enimidothioate + D-glucose + H(+)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Canis familiaris)


name: dioscin + 3 H2O => diosgenin + 2 L-rhamnopyranose + D-glucose


name: argininosuccinate <=> fumarate + arginine (Rattus norvegicus)


name: activation of actin cross-linking activity


name: Degradation multiubiquitinated Cyclin A (Mus musculus)


name: HDAC8 deacetylates histones (Canis familiaris)


name: regulation of electron transfer flavoprotein


name: nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate


name: PANK4 hydrolyzes PPANT to pantetheine (Canis familiaris)


name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid (Homo sapiens)


name: PIAS1 SUMOylates SATB2 with SUMO3 (Sus scrofa)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)


name: beta-nicotinamide D-riboside + ATP => beta-nicotinamide D-ribonucleotide + ADP + H(+)


name: salicylaldehyde + NAD(+) + H2O => salicylate + NADH + 2 H(+)


name: UGT1A3 lactonizes 2-OH-ATV to 2-OH-ATVL (Sus scrofa)


name: SULT1A1 dimer sulfonates NHABP (Xenopus tropicalis)


name: an N-hydroxyarylamine + acetyl-CoA <=> an N-acetoxyarylamine + CoA


name: 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate <=> (-)-alpha-amorphene + diphosphate


name: PTPN12 dephosphorylates PDGFRB at Y1021 (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + ADP + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + ATP


name: (2S)-2-hydroxypentanenitrile => butanal + hydrogen cyanide


name: STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Mus musculus)


name: androst-4-ene-3,17-dione + NADPH + H(+) => testosterone + NADP(+)


name: pentan-3-one + NADP(+) => pent-1-en-3-one + NADPH + H(+)


name: NUAK1 phosphorylates TP53 (Homo sapiens)


name: ABHD4 hydrolyses NAPE (Drosophila melanogaster)


name: L-proline(out) + H(+)(out) => L-proline(in) + H(+)(in)


name: JMJD6 dimer hydroxylates lysine residues of U2AF2 (Xenopus tropicalis)


name: GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Mus musculus)


name: 2',3'-cyclophospho-CMP + H2O => cytidine 2'-phosphate + H(+)


name: Phosphorylation of MEF2 proteins by p38 (Bos taurus)


name: B4GAT1:GYLTL1B transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Bos taurus)


name: (S)-allantoin + H2O => allantoate + H(+)


name: Removal of fibrillar collagen C-propeptides (Sus scrofa)


name: Association of Acrosin Heavy and Light Chain (Bos taurus)


name: positive regulation of signal transduction in other organism


name: glyoxal + GMP = N(2)-(1-hydroxy-2-oxoethyl)-GMP


name: stimulation of B cell receptor signaling pathway


name: N2 + 12 reduced [2Fe-2S]-[ferredoxin] + 40 ATP + 40 H2O <=> 3 H2 + 12 oxidized [2Fe-2S]-[ferredoxin] + 2 NH4(+) + 40 ADP + 40 phosphate + 26 H(+)


name: LONP1 binds mitochondrial inner membrane proteins (Sus scrofa)


name: (S)-2-hydroxyglutarate(in) + (S)-malate(out) => (S)-2-hydroxyglutarate(out) + (S)-malate(in)


name: (2E)-13-methyltetradecenoyl-CoA + H2O => 3-hydroxyisopentadecanoyl-CoA


name: Carbonic anhydrase VI dehydrates bicarbonate to water and carbon dioxide (Canis familiaris)


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Mus musculus)


name: [pyruvate dehydrogenase (lipoamide)] phosphatase, intrinsic regulator activity


name: (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O <=> (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + L-glutamate


name: 1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)


name: bisphenol A + NADH + O2 + H(+) <=> 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD(+) + H2O


name: p-Y701-STAT1 dimer translocates from the cytosol to the nucleus (Rattus norvegicus)


name: Proteasome mediated degradation of Cyclin D1 (Xenopus tropicalis)


name: S-methyl-5-thio-alpha-D-ribose 1-phosphate <=> 5-(methylsulfanyl)ribulose 1-phosphate


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Schizosaccharomyces pombe)


name: ganoderate DM + reduced [NADPH--hemoprotein reductase] + O2 => hainanate A + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: L-tyrosine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 <=> (E)-4-hydroxyphenylacetaldehyde oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)


name: Condensin II complex binds H4K20me1-containing nucleosomes (Dictyostelium discoideum)


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Bos taurus)


name: SORD oxidizes D-sorbitol to Fru (Xenopus tropicalis)


name: Activation of alpha-linolenic acid to alpha-linolenoyl-CoA (Rattus norvegicus)


name: (2R,3R)-dihydroquercetin + reduced [NADPH--hemoprotein reductase] + O2 => (2R,3R)-dihydromyricetin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) => UDP-N-acetyl-alpha-D-glucosamine + diphosphate


name: p-SHC1 binds integrin alpha5beta1:fibronectin (Mus musculus)


name: D-mannitol 1-phosphate + H2O => D-mannitol + phosphate


name: 2 oxidized [2Fe-2S]-[ferredoxin] + NAD(+) + 2 NADPH => 2 reduced [2Fe-2S]-[ferredoxin] + NADH + 2 NADP(+) + H(+)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Mus musculus)


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + O-phospho-L-seryl-[protein] => O-diphospho-L-seryl-[protein] + 1D-myo-inositol hexakisphosphate


name: taurine(in) + chloride(in) + 2 Na(+)(in) => taurine(out) + chloride(out) + 2 Na(+)(out)


name: Exocytosis of azurophil granule lumen proteins (Caenorhabditis elegans)


name: ALOX5 oxidises 17(R)-HDHA to 7(S)-Hp-17(R)-HDHA (Canis familiaris)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Canis familiaris)


name: Glycine, Serine and Threonine Metabolism Pathway


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Canis familiaris)


name: F-actin capping protein is a heterodimer (Canis familiaris)


name: L-glutamyl-5'-AMP + holo-[peptidyl-carrier protein] => L-glutamyl-[peptidyl-carrier protein] + AMP + H(+)


name: Decreased Striated Muscle Aspartate Activity


name: PXLP-K56-SRR dimer isomerises L-Ser to D-Ser (Mus musculus)


name: emetine + S-adenosyl-L-homocysteine + H(+) => cephaeline + S-adenosyl-L-methionine


name: HYKK phosphorylates 5HLYS (Homo sapiens)


name: PGLYRP2 hydrolyzes bacterial peptidoglycan (Gallus gallus)


name: sABO-B:Mn2+ transfers Gal to H antigen-sec to form B antigen (Bos taurus)


name: Unwinding of DNA for the Nascent Transcript: Second Transition (Caenorhabditis elegans)


name: NOTCH1 PEST domain mutants stimulate HES5 transcription (Homo sapiens)


name: 2-hydroxy-3-oxopropanoate + pyruvate => 2-dehydro-3-deoxy-D-glucarate


name: USP21 deubiquitinates RIPK1,DDX58 (Drosophila melanogaster)


name: (2E)-5-methylhexenoyl-[ACP] + NADH + H(+) => 5-methylhexanoyl-[ACP] + NAD(+)


name: indole-3-carbaldehyde + O2 + H2O => indole-3-carboxylate + H2O2 + H(+)


name: cAMP degradation by Phosphodiesterases (Sus scrofa)


name: aminoacetaldehyde + 2 oxidized [4Fe-4S]-[ferredoxin] + H2O = 2 reduced [4Fe-4S]-[ferredoxin] + glycine + 3 H(+)


name: androstan-3alpha,17beta-diol + NAD(+) => 17beta-hydroxyandrostanone + NADH + H(+)


name: desmosterol + NADP(+) => 7-dehydrodesmosterol + NADPH + H(+)


name: G-beta:G-gamma inhibits Adenylate cyclase (Xenopus tropicalis)


name: (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FAD + 2 H2O => (5-chloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + FADH2 + chloride + O2


name: 1-nonadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Bos taurus)


name: hydrolase activity, hydrolyzing O-glycosyl compounds


name: Methylthio-ribose-P = Methylthio-ribulose-P (Homo sapiens)


name: L-lysyl-[protein] + O2 + H2O <=> (S)-2-amino-6-oxohexanoyl-[protein] + H2O2 + NH4(+)


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Caenorhabditis elegans)


name: aromatic (S)-hydroxynitrile lyase activity


name: LCNs bind lipids (Drosophila melanogaster)


name: NR1H2,3 binds the CETP gene (Homo sapiens)


name: GPX3 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Gallus gallus)


name: NUDT12 hydrolyses NADH to NMNH (Canis familiaris)


name: p-Y694-STAT5A, p-STAT5B dimerizes (Gallus gallus)


name: NID1 degradation by MMP1, 9, 12, ELANE (Homo sapiens)


name: (S)-beta-macrocarpene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 <=> zealexin A1 + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Mus musculus)


name: abacavir [extracellular] => abacavir [cytosol] (Xenopus tropicalis)


name: 2 L-tyrosyl-tRNA(Tyr) <=> cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)


name: (11E)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> (5Z,11E)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: MGMT/hAGT mediated DNA Damage Reversal (Homo sapiens)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Homo sapiens)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Sus scrofa)


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Homo sapiens)


name: Phosphorylated STAT1, STAT3 form dimers (Canis familiaris)


name: Hydrolysis of PC to PA by PLD (Schizosaccharomyces pombe)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Sus scrofa)


name: iodide(in) + chloride(out) <=> iodide(out) + chloride(in)


name: low-affinity D-glucose:proton symporter activity


name: low-affinity glucose:proton symporter activity


name: 3alpha(S)-strictosidine + H2O => secologanin + tryptamine


name: kermesate + UDP-alpha-D-glucose <=> carminate + UDP + 2 H(+)


name: N(6)-acyl-L-lysyl-[protein] + NAD(+) + H2O => 2''-O-acyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: D-glycero-beta-D-manno-heptose 7-phosphate + ATP <=> D-glycero-beta-D-manno-heptose 1,7-bisphosphate + ADP + H(+)


name: 2 (E)-prop-1-en-1-SO-peroxol = thiosulfinate + H2O


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + hexadecanoate + H(+)


name: a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> a 1-[(6Z,9Z,12Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: IDS hydrolyses Heparan sulfate chain(5) (Drosophila melanogaster)


name: DMBT1 binds SFTPD 12mer, SFTPAs (Canis familiaris)


name: 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(out) + ADP + phosphate + H(+) => 5,7-dimethyl-2-methylamino-4-(3-pyridylmethyl)-1,3-benzothiazol-6-yl sulfate(in) + ATP + H2O


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + an N-acylsphing-4-enine = an N-acylsphing-4-enine-(1D-myo-inositol) + a 1,2-diacyl-sn-glycerol


name: PCK1 phosphorylates OA to yield PEP (Drosophila melanogaster)


name: CHUK, IKBKB phosphorylate CYLD at S418 (Drosophila melanogaster)


name: Ag(+)(in) + ATP + H2O = Ag(+)(out) + ADP + phosphate + H(+)


name: (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP


name: oxaloacetate + acetyl-CoA + ADP + phosphate <=> citrate + ATP + CoA


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Rattus norvegicus)


name: Calcineurin binds and dephosphorylates NFAT1 in response to WNT/Ca2+ signaling (Drosophila melanogaster)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Rattus norvegicus)


name: kaempferol + UDP-beta-L-rhamnose <=> kaempferol 3-O-alpha-L-rhamnoside + UDP + H(+)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Caenorhabditis elegans)


name: tetrahydrotyrosine + 3-phenylpyruvate => tetrahydro-4-hydroxyphenylpyruvate + L-phenylalanine


name: perillyl aldehyde + NADP(+) + H2O = perillate + NADPH + 2 H(+)


name: SLC29A3 transports nucleosides from cytosol to lysosomal lumen (Plasmodium falciparum)


name: L-tyrosine(in) + ADP + phosphate + H(+) => L-tyrosine(out) + ATP + H2O


name: PLA2s hydrolyze phospholipids at the Golgi membrane (Danio rerio)


name: (6E)-8-methylnon-6-enoyl-CoA + 4-hydroxy-3-methoxy-benzenemethanol <=> capsiate + CoA


name: Removal of RNA primer and dissociation of RPA and Dna2 (Mus musculus)


name: Phosphorylation of Syntaxin-4 (Rattus norvegicus)


name: MECR dimer reduces tdec2-CoA to DEC-CoA (Sus scrofa)


name: SOCS-1 and SOCS-3 binds to p-JAK2 (Canis familiaris)


name: 17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] => 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: CDC42 translocates to the endoplasmic reticulum membrane (Dictyostelium discoideum)


name: D-ribose 5-phosphate + AMP + 2 H(+) => ADP-D-ribose + H2O


name: FOXG1 binds FOXO:SMAD complexes (Danio rerio)


name: ANO1 transports cytosolic Cl- to extracellular region (Gallus gallus)


name: Activation of conventional Protein Kinase C (Mus musculus)


name: Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Xenopus tropicalis)


name: isomeliandiol + acetyl-CoA => 21-O-acetyl-isomeliandiol + CoA


name: D-glucono-1,5-lactone 6-phosphate + H2O => 6-phospho-D-gluconate (Schizosaccharomyces pombe)


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP => 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Homo sapiens)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + UMP + NADPH + H(+) => 5-methyl-UMP + (6S)-5,6,7,8-tetrahydrofolate + NADP(+)


name: dihydroxyacetone phosphate + acetyl-CoA = 3-hydroxy-2,4-dioxopentyl phosphate + CoA


name: TBK1 phosphorylation (Rattus norvegicus)


name: IL24 binds to IL22RA1:JAK1:IL20RB (Canis familiaris)


name: holo-[cytochrome c] = apo-[cytochrome c] + heme b


name: 2alpha-hydroxytaxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Homo sapiens)


name: urocanate + H2O => 4-imidazolone-5-propionate (Homo sapiens)


name: RBX1:CUL3 dissociates from forming autophagosome (Canis familiaris)


name: I1P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Dictyostelium discoideum)


name: a long-chain fatty acid + ATP + H(+) = a long-chain fatty acyl-AMP + diphosphate


name: myo-inositol + ATP = 1D-myo-inositol 3-phosphate + ADP + H(+)


name: D-serine(in) + L-alanine(out) => D-serine(out) + L-alanine(in)


name: UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-glutamate <=> UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-oxoglutarate


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Canis familiaris)


name: p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Bos taurus)


name: negative regulation of voltage-gated sodium channel activity


name: BTN3A1 and BTN1A1 binds periplakin (PPL) (Homo sapiens)


name: dapdiamide A + ADP + phosphate + H(+) => N(3)-fumaramoyl-(S)-2,3-diaminopropanoate + L-valine + ATP


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Gallus gallus)


name: Exocytosis of specific granule lumen proteins (Sus scrofa)


name: CSNK1A1 and ADRBK1 dissociate from p-SMO dimer (Homo sapiens)


name: androsterone 3alpha-sulfate(out) + 2 Na(+)(out) <=> androsterone 3alpha-sulfate(in) + 2 Na(+)(in)


name: KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Bos taurus)


name: Coumarin is 7-hydroxylated by CYP2A6 (Drosophila melanogaster)


name: butanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxybutanoyl-CoA + succinate + CO2


name: 5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al (Canis familiaris)


name: T1R1/T1R3 dimer is the umami taste receptor (Bos taurus)


name: Palmostatin B binds RAS depalmitoylases (Drosophila melanogaster)


name: 2 Fe(II)-[cytochrome b1] + CO2 + H(+) => 2 Fe(III)-[cytochrome b1] + formate


name: p-S MAPK6,4:p-T182 MAPKAPK5 translocate to the cytosol (Danio rerio)


name: isobutyryl-CoA + FAD => methacrylyl-CoA + FADH2 (Dictyostelium discoideum)


name: an N-(very-long-chain fatty acyl)-sphingoid base + CoA + H(+) => a very long-chain fatty acyl-CoA + a sphingoid base


name: [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] + AH2 => [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + L-cysteinyl-[cysteine desulfurase] + A + AMP + H(+)


name: a ganglioside GD1b (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside Gal-GD1b (d18:1(4E)) + UDP + H(+)


name: NNT dimer transfers proton from NADPH to NAD+ (Canis familiaris)


name: 9,12-cis-hexadecadienoic acid delta 15 desaturase activity


name: 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)


name: (R)-salsolinol + S-adenosyl-L-methionine => N-methyl-(R)-salsolinol + S-adenosyl-L-homocysteine + H(+)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Dictyostelium discoideum)


name: IL12 bound to IL12R internalises (Gallus gallus)


name: 2 hydroxylamine + 2 NAD(+) <=> hyponitrous acid + 2 NADH + 2 H(+)


name: stimulation of aldosterone metabolic process


name: beta-alanine(out) + n H(+)(in) => beta-alanine(in) + n H(+)(out)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Plasmodium falciparum)


name: (+-)-pavine + S-adenosyl-L-methionine = N-methylpavine + S-adenosyl-L-homocysteine + H(+)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine => a 5'-end (5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine


name: carbamoyl-phosphate synthase (ammonia) activity


name: Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Drosophila melanogaster)


name: coclaurine + S-adenosyl-L-homocysteine + H(+) => norcoclaurine + S-adenosyl-L-methionine


name: PAK1-3 phosphorylates VE-cadherin (Caenorhabditis elegans)


name: "gibberellin A4 carboxyl methyltransferase"


name: HLCS biotinylates ACACA:Mn2+ (Plasmodium falciparum)


name: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + NADPH + H(+)


name: negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator


name: a sphingoid base + ATP => a sphingoid 1-phosphate + ADP + H(+)


name: TNF-α:TNFR1 binds DENN/MADD (Canis familiaris)


name: Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Caenorhabditis elegans)


name: PDCL promotes formation of G-beta:G-gamma heterodimers (Mus musculus)


name: Exocytosis of azurophil granule lumen proteins (Canis familiaris)


name: Activated ERBB2 binds PTK6 (BRK) (Sus scrofa)


name: gluconapin + AH2 + O2 = progoitrin + A + H2O


name: quinolinate + 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) => nicotinate beta-D-ribonucleotide + CO2 + diphosphate


name: YWHAB (14-3-3 beta/alpha) dimer binds phosphorylated YAP1 (Caenorhabditis elegans)


name: phosphinate(out) + ATP + H2O => phosphinate(in) + ADP + phosphate + H(+)


name: SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: Apical transport of Cipro to extracellular space (Homo sapiens)


name: 2-dehydro-3-deoxy-D-gluconate + NH4(+) => 2-amino-2-deoxy-D-gluconate


name: PGH2 is isomerised to PGD2 by PTGDS (Bos taurus)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + AH2 + O2 => (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + A + 2 H2O


name: SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Mus musculus)


name: Cohesin binds PDS5 and WAPAL (Homo sapiens)


name: SLC2A1,3 transports DeHA from extracellular region to cytosol (Danio rerio)


name: cyanidin + UDP-alpha-D-glucose = cyanidin 3-O-beta-D-glucoside + UDP + H(+)


name: N-deacetylipecoside + H2O = secologanin + dopamine


name: MBTPS1 (S1P) cleaves CREB3L3 (Xenopus tropicalis)


name: glutathione + NADP(+) + CoA <=> CoA-glutathione + NADPH + H(+)


name: cyclohexanone + NADPH + O2 + H(+) = hexano-6-lactone + NADP(+) + H2O


name: acetyl-CoA + CO2 + NADPH => pyruvate + NADP(+) + CoA


name: 2-octadecanoyl-sn-glycero-3-phosphocholine + 1-nonadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-nonadecanoyl-sn-glycero-3-phosphocholine


name: MBL binds to repetitive carbohydrate structures on the surfaces of viruses, bacteria, fungi, and protozoa (Bos taurus)


name: SKI complexes with the Smad complex, suppressing BMP2 signalling (Bos taurus)


name: anthranilate + S-adenosyl-L-methionine => O-methyl anthranilate + S-adenosyl-L-homocysteine


name: MANBA hydrolyses GlcNAc:Man (Danio rerio)


name: N-methylputrescine + O2 + H2O <=> 4-methylaminobutanal + H2O2 + NH4(+)


name: GTP loading by Rheb (Caenorhabditis elegans)


name: (-)-casbene + reduced [NADPH--hemoprotein reductase] + O2 = 8-hydroxycasbene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: phycourobilin-L-cysteinyl(84)-[R-phycocyanin alpha-subunit] = apo-L-cysteinyl(84)-[R-phycocyanin alpha-subunit] + (2R,3E)-phycoerythrobilin


name: "R-phycocyanin alpha-cysteine-84 phycourobilin lyase/isomerase"


name: RHOC binds effectors at the plasma membrane (Canis familiaris)


name: O(6)-methyl-dGMP + diphosphate + H(+) => O(6)-methyl-dGTP + H2O


name: 5-methyl-phenazine-1-carboxylate + NADH + O2 + 2 H(+) = pyocyanin + CO2 + NAD(+) + H2O


name: (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O => 2-oxopent-4-enoate + formate + H(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H(+)


name: DEK binds TFAP2A homodimers (Sus scrofa)


name: Interaction of beta-2-microglobulin (B2M) chain with  class I HC (Rattus norvegicus)


name: methylenetetrahydrofolate reductase NADPH activity


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Bos taurus)


name: RNF41 ubiquitinates activated ERBB3 (Danio rerio)


name: CP110 and CEP97 dissociate from the centriole (Rattus norvegicus)


name: esculetin + S-adenosyl-L-methionine <=> isoscopoletin + S-adenosyl-L-homocysteine + H(+)


name: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA <=> 3-oxopristanoyl-CoA + CoA


name: SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) (Rattus norvegicus)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Bos taurus)


name: Reduction of disulphide bonds in MHC II antigens (Caenorhabditis elegans)


name: PNKP hydrolyzes the terminal 3'Pi at the NEIL1,NEIL2-generated single strand break (SSB) (Dictyostelium discoideum)


name: 17beta-hydroxy-3,19-dioxo-5alpha-androstanone + reduced [NADPH--hemoprotein reductase] + O2 => 17beta-hydroxy-3-oxo-19-nor-5alpha-androst-1-ene + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: SLC27A1,4,6 transport LCFAs from extracellular region to cytosol (Saccharomyces cerevisiae)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)


name: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: 3-oxosphinganine + dodecanoyl-CoA <=> N-dodecanoyl-3-oxosphinganine + CoA + H(+)


name: NLRX1 inhibits MAVS-DDX58 interaction (Gallus gallus)


name: Coagulation factor V activated | Platelet poor plasma | Coagulation


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Homo sapiens)


name: NAD(P)+ transhydrogenase (Si-specific) activity


name: positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process


name: MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Drosophila melanogaster)


name: choloyl-CoA + H2O = S-choloyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: DHCR24 reduces ZYMOL to ZYMSTNL (Canis familiaris)


name: Transport of SEC22B, TAP and PLC from ER to ERGIC (Homo sapiens)


name: Dermatan sulfate can be further sulfated on position 2 of iduronate (Drosophila melanogaster)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-sn-glycerol + phosphate


name: Recruitment of GRB2:SOS to p-10Y-NTAL (Gallus gallus)


name: gibberellin A44,2-oxoglutarate:oxygen oxidoreductase activity


name: 7,8-dihydroneopterin 3'-triphosphate => 7,8-dihydromonapterin 3'-triphosphate


name: 4,5-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO2


name: Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Xenopus tropicalis)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Danio rerio)


name: 4-hydroxy-6-(16-hydroxy-2-oxohexadecyl)pyran-2-one + 3 CO2 + 4 CoA => 15-hydroxypentadecanoyl-CoA + 3 malonyl-CoA + 3 H(+)


name: FAD(out) + NAD(+)(in) => FAD(in) + NAD(+)(out)


name: Unwinding of DNA for the Nascent Transcript: Second Transition (Drosophila melanogaster)


name: glycocholate + L-histidine <=> L-histidocholate + glycine


name: 22-oxodocosanoate + reduced [NADPH--hemoprotein reductase] + O2 = docosanedioate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: cholesterol side-chain-cleaving enzyme activity


name: NPAS4 binds ARNT (Caenorhabditis elegans)


name: 7(1)-hydroxychlorophyllide a + NADP(+) => chlorophyllide b + NADPH + H(+)


name: 6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate => D-fructose 6-phosphate + (2S)-3-sulfolactaldehyde


name: 5-acetamidopentanoate + H2O = 5-aminopentanoate + acetate


name: alpha-pinene oxide => (Z)-2-methyl-5-isopropylhexa-2,5-dienal


name: PRDX1 overoxidizes (Saccharomyces cerevisiae)


name: MST1 dimer:MST1R dimer binds MST1R dimer (Canis familiaris)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Caenorhabditis elegans)


name: Tachykinin receptor 3 (NK3) binds to neurokinin B (Mus musculus)


name: MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Schizosaccharomyces pombe)


name: 3-(2-methylsulfanyl)ethylmalate => 2-(2-methylsulfanyl)ethylmaleate + H2O


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Gallus gallus)


name: Activated protein C:PROCR binds F2R (Bos taurus)


name: a 3-oxo-Delta(4)-steroid + AH2 => a 3-oxo-5beta-steroid + A


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Gallus gallus)


name: CYP2W1 oxidises INDOL (Drosophila melanogaster)


name: ALOX5 oxidises 15R-HETE to 15epi-LXA4/B4 (Rattus norvegicus)


name: (2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one + H2O = (2R,4S)-2-methyltetrahydrofuran-2,3,3,4-tetrol


name: 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + NADP(+) + H2O => 1-hydroxylimonen-2-one + NADPH + O2 + H(+)


name: 2 L-arginine + 3 NADH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NAD(+) + 4 H2O


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O => a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acid + H(+)


name: 1-acyl LPA is acylated to PA by AGPAT5 (OM) (Bos taurus)


name: thymine(out) + Na(+)(out) => thymine(in) + Na(+)(in)


name: MSH2:MSH3 binds insertion/deletion loop of 2 bases or more (Mus musculus)


name: Increased Sympathetic Epinephrine Activity


name: acetoacetyl-CoA + L-isoleucine + ATP => tenuazonic acid + AMP + diphosphate + CoA + 2 H(+)


name: regulation of methylenetetrahydrofolate reductase activity


name: folate + NADPH + H(+) => 7,8-dihydrofolate + NADP(+)


name: 25-hydroxycholest-1,4-dien-3-one + AH2 => cholest-1,4-dien-3-one + A + H2O


name: KSRP binds AU-rich element in 3' UTR of mRNA (Canis familiaris)


name: ISGylation of host protein filamin B (Mus musculus)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Drosophila melanogaster)


name: 3-methylbutanoyl-CoA + H2O => 3-methylbutanoate + CoA + H(+)


name: 7alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA = 3-oxochol-4,6-dien-24-oyl-CoA + H2O


name: Addition of galactose to Core 6 glycoprotein (Danio rerio)


name: USP17 deubiquitinates SUDS3 (Drosophila melanogaster)


name: 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 2-oxoglutarate + 2 O2 <=> 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 succinate + 2 CO2 + H2O


name: Phosphorylation of TEC kinases by p-SYK (Homo sapiens)


name: plaunotol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (2E,6E,10E)-geranylgeraniol + reduced [NADPH--hemoprotein reductase] + O2


name: (+)-kolavenyl diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: SEC4C,D bind GOSR2 and STX5 (Drosophila melanogaster)


name: Phosphorylation of pPTK2 by SRC (Rattus norvegicus)


name: trans-Golgi Network Lysosomal Vesicle Scission (Sus scrofa)


name: Addition of the first mannose to the N-glycan precursor by ALG1 (Dictyostelium discoideum)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: N(omega)-hydroxy-L-arginine + NAD(+) + H2O => L-arginine + NADH + O2 + H(+)


name: (S)-2-hydroxymethylglutarate <=> 2-methyleneglutarate + H2O


name: Phosphorylation of PIP2 to PIP3 by PI3K (Drosophila melanogaster)


name: terpentedienyl diphosphate => terpentetriene + diphosphate


name: atRAL is reduced to atROL (Mus musculus)


name: Activated TP receptor binds G-protein  G13 (Gallus gallus)


name: vanillate + NADH + O2 + H(+) => 3,4-dihydroxybenzoate + formaldehyde + NAD(+) + H2O


name: FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)


name: beta-cryptoxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> (5R,6S)-5,6-epoxi-beta-cryptoxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: Interaction of invariant chain trimer and MHC II alpha beta dimer (Rattus norvegicus)


name: a fatty acyl-[ACP] + a 1-acyl-sn-glycero-3-phosphate = a 1,2-diacyl-sn-glycero-3-phosphate + holo-[ACP]


name: Arachidonate is hydroxylated to 17-HETE by CYP(1) (Rattus norvegicus)


name: Activation of TAK1 complex bound to activated TLR4 complex (Canis familiaris)


name: 3,5-dioxohexanoate + H(+) => triacetate lactone + H2O


name: LDH tetramer reduces PYR to LACT (Danio rerio)


name: USP7 deubiquitinates monoubiquitinated PTEN (Drosophila melanogaster)


name: (9Z,12Z)-octadecadienoate + ATP + CoA <=> (9Z,12Z)-octadecadienoyl-CoA + AMP + diphosphate


name: The keratan chain can be capped by N-acetylneuraminic acid (Homo sapiens)


name: organelle ATP synthesis coupled electron transport


name: glutamate catabolic process via mesaconate and citramalate


name: N-(9Z-octadecenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside => beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4E-enine + cholesterol


name: an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) <=> an alpha-D-mannosyl-6-(1D-myo-inositol phospho)-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol


name: MRN complex bound to shortened telomeres recruits ATM (Schizosaccharomyces pombe)


name: Acireductone is created (Rattus norvegicus)


name: 2,2'-iminodipropanoate + NAD(+) + H2O <=> L-alanine + pyruvate + NADH + H(+)


name: Association of procollagen type III (Sus scrofa)


name: all-trans-zeta-carotene + A = all-trans-neurosporene + AH2


name: CYP2R1 25-hydroxylates VD3 to 25(OH)D (Sus scrofa)


name: Interleukin-16 is secreted (Xenopus tropicalis)


name: RAC2 binds effectors at the plasma membrane (Gallus gallus)


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> 4alpha-hydroxymethyl-4beta-methylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O


name: eburicol + S-adenosyl-L-methionine <=> (24Z)-ethylidenelanosterol + S-adenosyl-L-homocysteine + H(+)


name: 1-deoxy-3-dehydrosphinganine + CO2 + CoA => hexadecanoyl-CoA + L-alanine + H(+)


name: 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol => 4-O-[(D-ribitylphospho)(n)-D-ribitylphospho-(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)


name: serotonin(in) + 2 H(+)(out) = serotonin(out) + 2 H(+)(in)


name: TCR binds self-lipid-based antigen via CD1 (Homo sapiens)


name: Formation of the closed pre-initiation complex (Rattus norvegicus)


name: resolvin D1 + NAD(+) = 17-oxoresolvin D1 + NADH + H(+)


name: (S)-nicotine + reduced [NADPH--hemoprotein reductase] + O2 <=> (S)-nornicotine + formaldehyde + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Bos taurus)


name: RABGGTA binds RABGGTB (Schizosaccharomyces pombe)


name: Nuclear transport of pChREBP (Thr 666) protein (Canis familiaris)


name: PAKs autophosphorylate (Drosophila melanogaster)


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine => 1,3,3'-tri-O-methyl-4alpha-mannobiose + S-adenosyl-L-homocysteine + H(+)


name: DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA  (Bos taurus)


name: RAB31 GEFs exchange GTP for GDP on RAB31 (Mus musculus)


name: CNIH1 binds TFGA and AREG precursors (Sus scrofa)


name: (2E,6E,10E)-geranylgeranyl diphosphate = variediene + diphosphate


name: PXLP-K259-GOT1 transaminates 2-OG and L-Asp (Bos taurus)


name: 15k-LXA4 is reduced to dhk-LXA4 by PTGR1 (Homo sapiens)


name: 3-(3,4-dichlorophenyl)-1-methylurea + formaldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => diuron + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Plasmodium falciparum)


name: TRAM:TLR4:LY96:LPS:CD14 recruits TRIF (TICAM1) (Mus musculus)


name: Association of INK4 family proteins with CDK4/6 (Canis familiaris)


name: COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Rattus norvegicus)


name: 9-cis-retinal + NADH + H(+) => 9-cis-retinol + NAD(+)


name: tyramine + L-glutamate + ATP => gamma-L-glutamyltyramine + ADP + phosphate + H(+)


name: rhaponticin + malonyl-CoA => 6-O-malonyl-rhaponticin + CoA


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Danio rerio)


name: 3-demethylubiquinol-6 + S-adenosyl-L-methionine <=> ubiquinol-6 + S-adenosyl-L-homocysteine + H(+)


name: SLCO3A1 isoform 1 has abroad substrate specificity (Bos taurus)


name: chenodeoxycholate + NAD(+) => 7-oxolithocholate + NADH + H(+)


name: L-fucose + an alcohol => an alpha-L-fucoside + H2O


name: N(6)-(3-O-phospho-D-psicosyl)-L-lysyl-[protein] + ADP + H(+) => N(6)-(D-psicosyl)-L-lysyl-[protein] + ATP


name: [DsbA protein]-dithiol + a quinone <=> [DsbA protein]-disulfide + a quinol


name: BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Mus musculus)


name: MRN complex binds CDK2 and RBBP8 (Mus musculus)


name: 3-dehydrolevoglucosan + NADH + H(+) => levoglucosan + NAD(+)


name: ARBB recruits GPCRs into clathrin-coated pits (Rattus norvegicus)


name: butan-1-ol + NADP(+) <=> butanal + NADPH + H(+)


name: (2E,6E)-farnesyl diphosphate + H2O = (1S,6S,7R)-sesquipiperitol + diphosphate


name: Caspase-mediated cleavage of farnesyltransferase/geranyl- geranyltransferase subunit alpha  (Danio rerio)


name: DHFR dimer reduces FOLA to DHF (Rattus norvegicus)


name: IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Gallus gallus)


name: 4-chloro-L-threonyl-[peptidyl-carrier protein] + succinate + CO2 + H2O => L-threonyl-[peptidyl-carrier protein] + chloride + 2-oxoglutarate + O2 + H(+)


name: 2-all-trans-nonaprenylphenol + NADPH + O2 + H(+) <=> 3-(all-trans-nonaprenyl)benzene-1,2-diol + NADP(+) + H2O


name: a flavanone => a (E)-2'-hydroxy-chalcone


name: sungeidine A + sulfate + H(+) => sulfosungeidine F


name: butanoyl-CoA + NADP(+) = (2E)-butenoyl-CoA + NADPH + H(+)


name: The complex of RUNX1 and YAP1 binds the ITCH gene promoter (Homo sapiens)


name: SALMs1-3 bind each other in cis interactions (Danio rerio)


name: PGAM5 dodecamer dephosphorylates p-S336-ME1 (Sus scrofa)


name: 2-deoxy-D-glucose 6-phosphate + NADP(+) => 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + H(+)


name: DHFR dimer reduces FOLA to DHF (Bos taurus)


name: Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)


name: Molybdenum ion transfer onto molybdopterin (Mus musculus)


name: (2E)-octenoyl-[ACP] + NADH + H(+) => octanoyl-[ACP] + NAD(+)


name: activation of high-potential iron-sulfur carrier


name: SOD1 catalyzes 2H+ + O2.- => O2 + H2O2 (mitochondrial intermembrane space) (Canis familiaris)


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Bos taurus)


name: (12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(N(6),2'-O-dimethyladenosine) in mRNA + S-adenosyl-L-homocysteine + H(+) => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyladenosine) in mRNA + S-adenosyl-L-methionine


name: tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 13-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: alpha-muurolene + diphosphate => (2E,6E)-farnesyl diphosphate


name: aldehydo-N-acetyl-D-mannosamine + ATP => aldehydo-N-acetyl-D-mannosamine 6-phosphate + ADP + H(+)


name: SLC38A9 binds Ragulator:Rag dimers (Xenopus tropicalis)


name: GGCX gamma-carboxylates BGLAP(24-100) (pro-osteocalcin) (Canis familiaris)


name: TFAP2B homodimer binds YEATS4 (Caenorhabditis elegans)


name: The Ligand:GPCR:Gi complex dissociates (Gallus gallus)


name: Full activation of MMP1 (Canis familiaris)


name: 18-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose => (9Z)-18-hydroxyoctadec-9-enoate 18-O-beta-D-glucoside + UDP + H(+)


name: nerol + diphosphate => neryl diphosphate + H2O


name: Exocytosis of platelet alpha granule contents (Mus musculus)


name: RNF146 ubiquitinates ADP-ribosylated AXIN (Bos taurus)


name: USP12, USP26 deubiquitinate AR (Bos taurus)


name: neamine + 5-phospho-alpha-D-ribose 1-diphosphate => 5''-phosphoribostamycin + diphosphate


name: Dephosphorylation of p-STAT1 dimer by nuclear isoform of TCPTP (Drosophila melanogaster)


name: ubiquinone-8 + (S)-malate => ubiquinol-8 + oxaloacetate


name: a bacteriochlorophyllide c + S-adenosyl-L-methionine + H2O = a 7(1)-hydroxybacteriochlorophyllide c + 5'-deoxyadenosine + L-methionine + H(+)


name: Release of platelet secretory granule components (Sus scrofa)


name: RUNX2 and RB1 bind the BGLAP gene promoter (Homo sapiens)


name: DCC interaction with Ezrin (Mus musculus)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Rattus norvegicus)


name: VEGFA,B,PLGF bind to VEGFR1 leading to receptor dimerization (Rattus norvegicus)


name: STUB1 ubiquitinates RIPK3 at K55, K363 (Rattus norvegicus)


name: an aliphatic primary amide = an aliphatic nitrile + H2O


name: N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+) => N(6)-D-ribulosyl-L-lysyl-[protein] + ATP


name: (E)-non-2-enal + NAD(+) + H2O <=> (E)-non-2-enoate + NADH + 2 H(+)


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Sus scrofa)


name: beta-alanine + pyruvate + NADH + H(+) => (R)-beta-alanopine + NAD(+) + H2O


name: SEMA4D interacts with Plexin-B1:Met (Bos taurus)


name: VKORC1 inhibitors binds VKORC1 dimer (Xenopus tropicalis)


name: GTSE1 binds microtubule lattice in interphase cells (Canis familiaris)


name: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine => 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine + H(+)


name: D-xylose(in) + H(+)(in) = D-xylose(out) + H(+)(out)


name: L-erythrulose 1-phosphate = D-erythrulose 4-phosphate


name: staphylopine + NADP(+) + H2O = (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + pyruvate + NADPH + H(+)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Plasmodium falciparum)


name: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose


name: isopentadecanoyl-CoA + NADP(+) => (2E)-13-methyltetradecenoyl-CoA + NADPH + H(+)


name: "benzil reductase [(S)-benzoin forming]"


name: glycyl-L-glutamine(in) + ADP + phosphate + H(+) => glycyl-L-glutamine(out) + ATP + H2O


name: p-BRAF and RAF fusion dimers bind MAP2Ks and MAPKs (Homo sapiens)


name: 9beta-pimara-7,15-diene + diphosphate => 9alpha-copalyl diphosphate


name: SMAD1:SMAD4 trimer binds ZNF423 (Homo sapiens)


name: 4-amino-4-deoxychorismate <=> 4-aminobenzoate + pyruvate + H(+)


name: Activated FGFR1:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: ROS oxidize thioredoxin (Drosophila melanogaster)


name: Axonal transport of NGF:Trk complexes (Homo sapiens)


name: GLUT2 (SLC2A2) transports Glc from cytosol to extracellular region (Caenorhabditis elegans)


name: MUT isomerises L-MM-CoA to SUCC-CoA (Rattus norvegicus)


name: a neolactoside nLc4Cer + GDP-beta-L-fucose <=> a neolactoside III(3)-alpha-Fuc-nLc4Cer + GDP + H(+)


name: Association of procollagen type I (Sus scrofa)


name: Translocation of YAP1 to the nucleus (Caenorhabditis elegans)


name: CMBL hydrolyses OM to OLMS (Danio rerio)


name: RCHY1 monoubiquitinates POLH (Bos taurus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 <=> (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: 3-oxooctanoyl-[ACP] + NADPH + H(+) => (3R)-hydroxyoctanoyl-[ACP] + NADP(+)


name: WLS is endocytosed to the early endosome (Drosophila melanogaster)


name: F-actin capping protein is a heterodimer (Xenopus tropicalis)


name: 17-O-acetylajmaline + H2O = ajmaline + acetate + H(+)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: apo-[cytochrome c] + heme b => holo-[cytochrome c]


name: 1-hydroxy-4-methylpentan-2-one + NH4(+) + NADH + H(+) => (S)-leucinol + NAD(+) + H2O


name: 6'-oxoparomamine + L-glutamate => neamine + 2-oxoglutarate


name: (9Z)-hexadecenamide + H2O = (9Z)-hexadecenoate + NH4(+)


name: H2O2 oxidises ferrohemoglobin to MetHb (Danio rerio)


name: Vanin hydrolyses pantetheine to PanK, 2AET (Sus scrofa)


name: CHIT1 hydrolyses CHIT to 3xADGP (Danio rerio)


name: POLD,POLE binds deISGylated PCNA after TLS (Drosophila melanogaster)


name: LAIR2 binds collagen (Rattus norvegicus)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O => 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA


name: tetracosanoate + glycerol + H(+) => 1-tetracosanoylglycerol + H2O


name: Nuclear translocation of p38 MAPK (Gallus gallus)


name: (2E,6E,10E,14E)-geranylfarnesyl diphosphate <=> beta-geranylfarnesene + diphosphate


name: ALDH1L2 dehydrogenates 10-formyl-THFPG to THFPG (Caenorhabditis elegans)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Danio rerio)


name: 9alpha-copalyl diphosphate <=> stemar-13-ene + diphosphate


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Rattus norvegicus)


name: Phosphorylation of UBF-1:rDNA Promoter (Sus scrofa)


name: (24S)-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 <=> 24S,25-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Zinc is an agonist of GPR39 (Bos taurus)


name: PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Caenorhabditis elegans)


name: adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine => N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine + H(+)


name: RHOB binds effectors at the plasma membrane (Homo sapiens)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + UDP + H(+) => an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-N-acetyl-alpha-D-galactosamine


name: PIAS4 SUMOylates RNF168 with SUMO1 (Caenorhabditis elegans)


name: a 1,N(2)-etheno-2'-deoxyguanosine in double-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyguanosine in double-stranded DNA + glyoxal + succinate + CO2


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Homo sapiens)


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Canis familiaris)


name: ATF5 translocates from the cytosol to the mitochondrial matrix (Homo sapiens)


name: ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Bos taurus)


name: decanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxododecanoyl-[ACP] + CO2 + CoA


name: (2E)-octadecenoyl-CoA + H2O2 => octadecanoyl-CoA + O2


name: hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> (14E)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: D-ribono-1,4-lactone + NADH + H(+) <=> D-ribose + NAD(+)


name: 2-phenylethylamine + A + H2O => 2-phenylacetaldehyde + AH2 + NH4(+)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + Na(+)(out) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + Na(+)(in)


name: IL12B translocates from the cytosol to the extracellular region (Rattus norvegicus)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Bos taurus)


name: Phosphorylated Cdc6 is exported from the nucleus (Schizosaccharomyces pombe)


name: cyclohexanone + A => cyclohex-2-enone + AH2


name: DNA polymerase processivity factor activity


name: 2-oxobutanoate + NH4(+) => (2S)-2-amino-3-butenoate + H2O


name: N-terminal L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-methionine <=> N-terminal N,N-dimethyl-L-prolyl-L-prolyl-L-lysyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: GRB2:SOS1 complex binds to EGF:EGFR complex (Danio rerio)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Bos taurus)


name: Phenol can form a sulfate conjugate (Canis familiaris)


name: (2E,4E)-2,4-dichloromuconate + H(+) => 2-(2,4-dichloro-5-oxo-2,5-dihydrofuryl)acetate


name: activation of tetrapyrrole catabolic process


name: ATP binds G-protein beta associated TRiC/CCT (Canis familiaris)


name: activation of aa3-type cytochrome c oxidase


name: MRN complex bound to shortened telomeres recruits ATM (Gallus gallus)


name: docosanoyl-CoA + O2 <=> (2E)-docosenoyl-CoA + H2O2


name: Engulfment of particulate antigen into phagocytic vesicle (Homo sapiens)


name: dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA (Sus scrofa)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Xenopus tropicalis)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Bos taurus)


name: NF-kappa-B inhibitor binds NF-kappa-B complex (Mus musculus)


name: S-adenosyl 3-(methylsulfanyl)propylamine + agmatine = N(1)-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine + H(+)


name: NSF ATPase activity dissociates cis-SNARE at cis-Golgi (Homo sapiens)


name: 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity


name: 2-amino-2-deoxy-D-gluconate(out) + N(pros)-phospho-L-histidyl-[protein] => 2-amino-2-deoxy-D-gluconate 6-phosphate(in) + L-histidyl-[protein]


name: 2-isopropylmaleate + H2O <=> (2S)-2-isopropylmalate


name: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+)


name: all-trans-zeaxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => beta-cryptoxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: aspulvinone E + 2 dimethylallyl diphosphate <=> aspulvinone H + 2 diphosphate


name: Disassociation of PLC-gamma1 from SLP-76 (Canis familiaris)


name: ricinine + 2 H2O <=> 4-methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxylate + NH4(+)


name: chanoclavine-I aldehyde + NADH + H(+) => chanoclavine-I + NAD(+)


name: (1E,2S)-2-methylbutanal oxime <=> (1Z,2S)-2-methylbutanal oxime


name: 9alpha,11alpha-methylene thromboxane A2 + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-9alpha,11alpha-methylene thromboxane A2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: dauca-4,7-diene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Translocation of Cyclin B1:phospho-Cdc2 to the cytoplasm (Danio rerio)


name: 2 Fe(III)-[cytochrome c550] + an aliphatic amine + H2O <=> 2 Fe(II)-[cytochrome c550] + an aldehyde + NH4(+) + 2 H(+)


name: Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Danio rerio)


name: 2-formylbenzoate dehydrogenase (NAD+) activity


name: CYSLTR1 binds CYSLTR1 antagonists (Drosophila melanogaster)


name: 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Saccharomyces cerevisiae)


name: dGDP + [thioredoxin]-disulfide + H2O <=> [thioredoxin]-dithiol + GDP


name: phylloquinol + [protein]-disulfide = phylloquinone + [protein]-dithiol


name: MLCL is hydrolyzed to DLCL by PLA2G4A (IM) (Schizosaccharomyces pombe)


name: AFG3L2 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: ASPA deacetylates NAASP to acetate and L-aspartate (Rattus norvegicus)


name: trans-aconitate(in) + citrate(out) = trans-aconitate(out) + citrate(in)


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Sus scrofa)


name: beta-myrcene + reduced [NADPH--hemoprotein reductase] + O2 <=> (4R)-ipsdienol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Saccharomyces cerevisiae)


name: a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+) => 2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA


name: Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize (Homo sapiens)


name: chondroitin sulphate proteoglycan activity


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Danio rerio)


name: creatinine + H2O + H(+) => N-methylhydantoin + NH4(+)


name: Binding of Grb10 to the insulin receptor (Sus scrofa)


name: NQO2:FAD dimer reduces quinones to hydroquinones (Rattus norvegicus)


name: PI(3,5)P2 is dephosphorylated to PI3P by FIG4 at the late endosome membrane (Sus scrofa)


name: (-)-coronaridine + reduced [NADPH--hemoprotein reductase] + O2 <=> (-)-10-hydroxycoronaridine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Tranport of L-Glutamate (mitochondrial matrix) to cytosol (Homo sapiens)


name: Engulfed CpG DNA binds to endosomal C-ter TLR9 (Bos taurus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Gallus gallus)


name: RHOD GAPs stimulate RHOD GTPase activity (Schizosaccharomyces pombe)


name: calcium-independent cell adhesion molecule activity


name: ABC-type oligopeptide transporter activity


name: glutamic phenylpyruvic aminotransferase activity


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: Phosphorylation of CREB1 by ribosomal protein S6 kinases (RSKs) (Gallus gallus)


name: pentadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate => 1-(9Z)-octadecenoyl-2-pentadecanoyl-sn-glycero-3-phosphate + CoA


name: Cleavage of uracil by TDG glycosylase (Canis familiaris)


name: GRK1,4,7 phosphorylate MII to p-MII (Gallus gallus)


name: Translocation of active Cdc25C to the nucleus (Sus scrofa)


name: IL36:IL1RL2 binds IL1RAP-1 (Xenopus tropicalis)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Mus musculus)


name: octanedioyl-CoA + H2O <=> octanedioate + CoA + H(+)


name: SREBP1A,2 binds the PMVK promoter (Homo sapiens)


name: dodecanoyl-CoA + taurine = N-dodecanoyl-taurine + CoA + H(+)


name: (6E)-8-hydroxygeranial + NADP(+) <=> (6E)-8-oxogeranial + NADPH + H(+)


name: inhibition of receptor tyrosine kinase autophosphorylation


name: positive regulation of cell wall integrity MAPK cascade


name: D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Homo sapiens)


name: ALDH1B1 tetramer oxidises CH3CHO to CH3COOH (Mus musculus)


name: STAT1 and STAT3 dimers translocate to the nucleus (Gallus gallus)


name: NR3C2 binds fludrocortisone (Xenopus tropicalis)


name: PXLP-K278-ETNPPL tetramer hydrolyses PETA (Xenopus tropicalis)


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Homo sapiens)


name: 4-pyridoxolactone + NADH + H(+) => pyridoxal + NAD(+)


name: deacetoxyvindoline + S-adenosyl-L-homocysteine + H(+) => (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine


name: (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + O2 <=> (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate + H2O2


name: (2E)-geranyl diphosphate = camphene + diphosphate


name: (3R)-hydroxy-(16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA = (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + H2O


name: Release of p-STAT2:p-STAT1 dimer (Mus musculus)


name: HSD17B3-like proteins reducde ANDST to TEST (Danio rerio)


name: NTPDase3 hydrolyzes nucleoside triphosphates (Mus musculus)


name: Transfer of ubiquitin from E1 to E2 (Mus musculus)


name: PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Bos taurus)


name: L-methionyl-[protein] + a quinone + H2O => L-methionyl-(S)-S-oxide-[protein] + a quinol


name: Phospho R-SMAD(SMAD2/3):CO-SMAD(SMAD4):FOXO3 binds FoxO3a-binding elements (Caenorhabditis elegans)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Schizosaccharomyces pombe)


name: STING binds c-di-GMP (Drosophila melanogaster)


name: 3,3'-diiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) => 3,3'-diiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: (indol-3-yl)butanoate + L-glutamine + ATP = (indol-3-yl)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: 1-dehydro-L-sorbose + AH2 => L-sorbopyranose + A


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by PTEN in the cytosol (Danio rerio)


name: L-dehydroascorbate + 2 glutathione => glutathione disulfide + L-ascorbate


name: ERKs are inactivated by protein phosphatase 2A (Saccharomyces cerevisiae)


name: MGLL gene expression is stimulated by PPARG:RXRA:MLL4,(MLL3)-ASCOM complex (Homo sapiens)


name: FA anion diffuses laterally to UCP (Xenopus tropicalis)


name: M2 mRNA is translated into protein M2-1 (Homo sapiens)


name: activation of stress-activated protein kinase signaling pathway


name: PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Rattus norvegicus)


name: (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+) => (S)-scoulerine + S-adenosyl-L-methionine


name: p-EFNB binds GRB4 (Drosophila melanogaster)


name: 19-hydroxytestosterone + reduced [NADPH--hemoprotein reductase] + O2 <=> 19-oxotestosterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: SLC29A1 transports RBV from cytosol to extracellular region (Homo sapiens)


name: KDM1A, KDM1B demethylate MeK5-histone H3 (Saccharomyces cerevisiae)


name: The p75NTR C-terminal fragment enters endosomes (Danio rerio)


name: adenosine(58) in tRNA + S-adenosyl-L-methionine => N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: validoxylamine A + 2-oxoglutarate + O2 => validoxylamine B + succinate + CO2 + H(+)


name: activation of mitochondrial electron transport, NADH to ubiquinone


name: p-MAPKAPK3 phosphorylates BMI1 (Danio rerio)


name: CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)


name: PYGM dimer, b form + 2 AMP <=> PYGM b dimer:AMP complex (Xenopus tropicalis)


name: 10-oxooctadecanoate + NADH + H(+) => 10-hydroxyoctadecanoate + NAD(+)


name: Cleavage of 5-hydroxyluracil by UNG glycosylase (Canis familiaris)


name: Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Sus scrofa)


name: (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H(+) => 2-dehydro-3-deoxy-D-gluconate + NADP(+)


name: apo-[BtrI ACP] + CoA = holo-[BtrI ACP] + adenosine 3',5'-bisphosphate + H(+)


name: p-S407,Y641-STAT6 is dimerized (Xenopus tropicalis)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O => a 1-acyl-sn-glycero-3-phosphate + ethanolamine + H(+)


name: Cho is phosphorylated to PCho by CHK dimer (Danio rerio)


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O <=> 1-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoate + H(+)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O