name: GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Homo sapiens)


name: Fibronectin degradation by ADAM8 (Caenorhabditis elegans)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Sus scrofa)


name: S-adenosylglutathione + cob(I)alamin-[alkylcobalamin reductase] + H(+) => apo-[alkylcobalamin reductase] + adenosylcob(III)alamin + glutathione


name: 3'-AMP(out) + phosphate(in) => 3'-AMP(in) + phosphate(out)


name: beta-alanine + pyruvate => 3-oxopropanoate + alanine (Homo sapiens)


name: JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Bos taurus)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Bos taurus)


name: SPINK5(490-624) binds KLK5 (Rattus norvegicus)


name: Binding of RRN3 to RNA Polymerase I (Dictyostelium discoideum)


name: K(+)(out) + ADP + phosphate + H(+) => K(+)(in) + ATP + H2O


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O => 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: Caspase mediated cleavage of HIP-55 (Canis familiaris)


name: B4GALTs transfer Gal to a branch of keratan (Sus scrofa)


name: p-S10 CDKN1B translocates to the cytosol (Sus scrofa)


name: p-PKR dimer phosphorylates eIF2-alpha (Homo sapiens)


name: L-asparaginyl-[protein] + H2O => L-aspartyl-[protein] + NH4(+)


name: Exocytosis of platelet dense granule content (Sus scrofa)


name: glutathione(out) + ADP + phosphate + H(+) => glutathione(in) + ATP + H2O


name: 11-beta-hydroxysteroid dehydrogenase (NADP+) activity


name: RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate


name: Activated FGFR3 phosphorylates FRS3 (Rattus norvegicus)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Rattus norvegicus)


name: ent-sandaracopimaradien-3beta-ol + reduced [NADPH--hemoprotein reductase] + O2 = oryzalexin E + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: genistein 7-O-beta-D-glucoside + H2O <=> genistein + beta-D-glucose


name: maleylacetate + NADPH + H(+) => 3-oxoadipate + NADP(+)


name: RRAGA,B exchanges GDP for GTP (Canis familiaris)


name: Interaction of DAP12 and NKp44 (Homo sapiens)


name: CA4:Zn2+ hydrates CO2 to HCO3- (Canis familiaris)


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Xenopus tropicalis)


name: ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA (Gallus gallus)


name: positive regulation of palmitaldehyde biosynthesis


name: RHAG transports NH4+ from cytosol to extracellular region (red blood cells) (Rattus norvegicus)


name: N(6)-[(S)-lactoyl]-L-lysyl-[protein] + H2O => (S)-lactate + L-lysyl-[protein]


name: CSF3 dimer:CSFR binds CSFR (Homo sapiens)


name: Release of activated MAD2 from kinetochores (Gallus gallus)


name: 2,4-diacetylphloroglucinol + H2O = 2-acetylphloroglucinol + acetate


name: neamine + UDP-alpha-D-glucose => 3''-deamino-3''-hydroxykanamycin B + UDP + H(+)


name: D-xylose(out) + 2 Na(+)(out) => D-xylose(in) + 2 Na(+)(in)


name: glycochenodeoxycholate(out) + 2 Na(+)(out) => glycochenodeoxycholate(in) + 2 Na(+)(in)


name: PI4P is dephosphorylated to PI by SYNJ at the plasma membrane (Mus musculus)


name: Opioid receptors bind opioid peptides (Danio rerio)


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Rattus norvegicus)


name: (E)-caffeoyl-CoA + putrescine <=> N-caffeoylputrescine + CoA + H(+)


name: Constitutive phosphorylation by GSK3 (Gallus gallus)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Homo sapiens)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Sus scrofa)


name: CHST4 transfers SO4(2-) from PAPS to Core 2 mucins (Gallus gallus)


name: 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NAD(+) + H2O => 4beta-formylmethyl-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADH + O2


name: Tenascins C, R, (X, N) bind fibronectin matrix (Homo sapiens)


name: aryl-CoA synthetase (ADP-forming) activity


name: N-methyltyramine + S-adenosyl-L-methionine = hordenine + S-adenosyl-L-homocysteine + H(+)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Schizosaccharomyces pombe)


name: o-orsellinate depside + H2O <=> 2 orsellinate + H(+)


name: CYP8B1 12-hydroxylates 4CHOL7a,24(S)DIOL (Danio rerio)


name: a ribonucleoside 5'-diphosphate + ADP => a ribonucleoside 5'-triphosphate + AMP


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Rattus norvegicus)


name: MITF-M-dependent ASAH1 expression (Homo sapiens)


name: poly((1,4)-alpha-glucosyl) glycogenin-2 + n orthophosphate => glycogenin-2 + n D-glucose 1-phosphate [PYGL] (Sus scrofa)


name: TRAF6 binds to p75NTR:NRIF (Canis familiaris)


name: S-(2-succinyl)-L-cysteinyl-[protein] => L-cysteinyl-[protein] + fumarate


name: Furin cleaves pro-protein S to protein S (Sus scrofa)


name: inhibition of methylbenzene metabolic process


name: SUMOylation of MDC1 with SUMO1 (Sus scrofa)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Xenopus tropicalis)


name: Cytosolic PHD2,3 hydroxylates proline residues on HIF1A (Rattus norvegicus)


name: D-glucuronate + NAD(+) + H2O => D-glucarate + NADH + 2 H(+)


name: novobiocic acid + S-adenosyl-L-homocysteine + H(+) => 8-desmethylnovobiocic acid + S-adenosyl-L-methionine


name: The receptor:G-protein complex releases GDP (Drosophila melanogaster)


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Rattus norvegicus)


name: Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)


name: Phosphorylated p130 (RBL2) binds SCF(Skp2):Cks1 complex (Gallus gallus)


name: ST3GAL3,4,6 transfer Neu5Ac to Type 2 chain to form Type 2 MSGG (Mus musculus)


name: RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc (Sus scrofa)


name: 11a-hydroxytigecycline + NADP(+) + H2O => tigecycline + NADPH + O2 + H(+)


name: (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactone => 9-cis-10'-apo-beta-carotenal + 2 O2


name: down regulation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Drosophila melanogaster)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Sus scrofa)


name: a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GM1b (d18:1(4E)) + CMP + H(+)


name: DNA polymerase alpha:primase binds at the origin (Caenorhabditis elegans)


name: PI4KB binds to ARF1/3:GTP at the Golgi membrane (Rattus norvegicus)


name: indoxyl sulfate(out) + a dicarboxylate(in) = indoxyl sulfate(in) + a dicarboxylate(out)


name: ent-cassa-12,15-diene + diphosphate => ent-copalyl diphosphate


name: 11-O-acetylcyathatriol + A => 11-O-acetylcyathin A3 + AH2


name: 4-hydroxylamino-2,6-dinitrotoluene + UDP-alpha-D-glucose => 4-hydroxylamino-2,6-dinitrotoluene-O-beta-D-glucoside + UDP + H(+)


name: AUF1 binds translation and heat shock proteins (Sus scrofa)


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + ATP + H2O <=> 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + ADP + phosphate + H(+)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Schizosaccharomyces pombe)


name: NFE2L2-dependent PGD gene expression (Homo sapiens)


name: activation of uridine diphosphoglucuronate-estriol 16-alpha-glucuronosyltransferase activity


name: Activated ATM phosphorylates ABL1 (Rattus norvegicus)


name: COMT transfers Met to DA to form 3MT (Rattus norvegicus)


name: 17alpha-estradiol + NAD(+) => estrone + NADH + H(+)


name: inhibition of membrane associated actin binding


name: C-ter TLR7 dimer binds HCQ (Xenopus tropicalis)


name: S100A1 binds TLR4:LY96 (Rattus norvegicus)


name: PPP5C dephosphorylates TP53BP1 (Sus scrofa)


name: D-mannonate + NAD(+) = keto-D-tagaturonate + NADH + H(+)


name: indole-3-carboxylate + H(+) <=> indole + CO2


name: 1-octadecanoyl-sn-glycero-3-phosphoethanolamine + 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + H(+) => 1-octadecanoyl-2-(15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: ganglioside GM1 (d18:1(4E)/18:0) + H2O <=> ganglioside GM2 (d18:1(4E)/18:0) + D-galactose


name: PDCL releases folded G-beta from TRiC/CCT (Mus musculus)


name: KDM6A, KDM6B, KDM7A demethylate Me2K28-histone H3 (Schizosaccharomyces pombe)


name: a ubiquinol + fumarate => a ubiquinone + succinate


name: (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + AH2 + 2-oxoglutarate + O2 + H(+) => (2S)-5,5-dimethylpiperidine-2-carboxylate + succinate + A + 2 CO2 + H2O


name: [(3R)-hydroxybutanoate](n) + H2O = [(3R)-hydroxybutanoate](n-4) + (3R)-hydroxybutanoate tetramer + H(+)


name: regulation of IRE1 signaling in response to endoplasmic reticulum stress


name: a ribonucleoside 5'-triphosphate + 2 H2O = a ribonucleoside 5'-phosphate + 2 phosphate + 2 H(+)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Danio rerio)


name: (2E,6E)-farnesyl diphosphate <=> (-)-beta-santalene + diphosphate


name: Activated MAPKs phosphorylate MAP2K1 (Danio rerio)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = cholesteryl (5Z,8Z,11Z)-eicosatrienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) (Sus scrofa)


name: LRP2 binds extracellular TCN2:RCbl (Canis familiaris)


name: SLC36A4 transports L-Trp from extracellular region to cytosol (Bos taurus)


name: methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP-beta-L-fucose => methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP + H(+)


name: CDK5 phosphorylates DARPP-32 on Thr75 (Xenopus tropicalis)


name: 8-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => dodecanoate + reduced [NADPH--hemoprotein reductase] + O2


name: M5 muscarinic acetylcholine receptor binding


name: regulation of systemic arterial blood pressure by norepinephrine


name: DCP1-DCP2 complex decaps mRNA (Gallus gallus)


name: PITRM1 proteolyzes mitochondrial targeting peptides (presequences) (Rattus norvegicus)


name: an N-acyl-D-mannosamine 6-phosphate + phosphoenolpyruvate + H2O => an N-acylneuraminate 9-phosphate + phosphate


name: PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Homo sapiens)


name: a quinol + NAD(+) + 4 H(+)(out) => a quinone + NADH + 5 H(+)(in)


name: a 5'-end CoA-ribonucleoside in mRNA + H2O <=> 3'-dephospho-CoA + a 5'-end phospho-ribonucleoside in mRNA + H(+)


name: Expression of ABCG8 regulated by NR1H2 or NR1H3 (Homo sapiens)


name: a ganglioside Ac-O-8-GD3 <=> a ganglioside Ac-O-9-GD3


name: 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+) => 1-O-alkyl-2-acyl-sn-glycerol + ATP


name: [thioredoxin]-disulfide + L-methionine + H2O <=> L-methionine (R)-S-oxide + [thioredoxin]-dithiol


name: squalene + 2 diphosphate + NADP(+) => 2 (2E,6E)-farnesyl diphosphate + NADPH + H(+)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Homo sapiens)


name: p-TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)


name: (3S,5S)-carbapenam-3-caboxylate + AMP + diphosphate + H(+) => (2S,5S)-5-carboxymethylproline + ATP


name: L-leucine(out) + chloride(out) + 2 Na(+)(out) <=> L-leucine(in) + chloride(in) + 2 Na(+)(in)


name: activation of phosphotyrosine histone phosphatase activity


name: 2-oxopentanoate + N(omega),N(omega)-dimethyl-L-arginine <=> 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-2-aminopentanoate


name: 7,8-dihydroneopterin 3'-phosphate = glycolaldehyde phosphate + 6-hydroxymethyl-7,8-dihydropterin


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+) => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H2O


name: Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)


name: SORD tetramer oxidizes xylitol to D-xylulose (Sus scrofa)


name: Delta(1)-dihydrotestosterone + A + H2O => 17beta-hydroxyandrostan-1,3-dione + AH2


name: SLC5A2 binds gliflozins (Rattus norvegicus)


name: hercynyl-SeGlcNAc selenoxide + AH2 => 2-acetamidoglucal + selenoneine + A + H2O


name: Exocytosis of platelet dense granule content (Xenopus tropicalis)


name: inhibition of bacterial catalase-peroxidase activity


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Canis familiaris)


name: a ganglioside Ac-O-8-GD3(d18:1(4E)) => a ganglioside Ac-O-9-GD3(d18:1(4E))


name: SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Sus scrofa)


name: L-alanyl-L-aspartate(out) + ATP + H2O <=> L-alanyl-L-aspartate(in) + ADP + phosphate + H(+)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Sus scrofa)


name: epitestosterone 17-sulfate(out) + 2 Na(+)(out) = epitestosterone 17-sulfate(in) + 2 Na(+)(in)


name: methanethiol + coenzyme M => methyl-coenzyme M + hydrogen sulfide + H(+)


name: di-trans,octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H(+)


name: SLC19A2/3 transport extracellular THMN to cytosol (Bos taurus)


name: 5,10-methylenetetrahydromethanopterin + NAD(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADH


name: 1,7-dimethylxanthine + NADPH + O2 + H(+) = 7-methylxanthine + formaldehyde + NADP(+) + H2O


name: (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + AH2 + 2-oxoglutarate + O2 + H(+) = (2S)-5,5-dimethylpiperidine-2-carboxylate + succinate + A + 2 CO2 + H2O


name: Release of 40S and 60S subunits from the 80S ribosome  (Danio rerio)


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Schizosaccharomyces pombe)


name: [DsrC protein]-dithiol + 2 a quinone + hydrogen sulfide + H(+) = [DsrC protein]-trisulfide + 2 a quinol


name: a uridine in 12S rRNA + S-adenosyl-L-methionine = a 5-methyluridine in 12S rRNA + S-adenosyl-L-homocysteine + H(+)


name: methyl (2E,6E)-farnesoate + reduced [NADPH--hemoprotein reductase] + O2 = juvenile hormone III + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: tetradecanoyl-CoA + malonyl-CoA + H(+) => 3-oxohexadecanoyl-CoA + CO2 + CoA


name: N,N-dimethylglycine + (6S)-5,6,7,8-tetrahydrofolate + O2 <=> sarcosine + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O2


name: perillyl aldehyde + NADH + H(+) => perillyl alcohol + NAD(+)


name: K63polyUb-RIPK1 is deubiquitinated (Bos taurus)


name: Defective CYP24A1 does not 24-hydroxylate CALTOL (Homo sapiens)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + di-trans,octa-cis-undecaprenyl diphosphate = an alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate


name: 17beta-estradiol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: retinol (vitamin A1) dehydrogenase activity


name: CERT1-2 complex binds ceramide (Homo sapiens)


name: Recruitment of STAT2 to p-IFNAR1 (Sus scrofa)


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Drosophila melanogaster)


name: (19E)-geissoschizine + reduced [NADPH--hemoprotein reductase] + O2 => rhazimal + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate = bonnadiene + diphosphate


name: β-blockers bind ADRB1,2,3 (Rattus norvegicus)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)


name: D-glucosamine 6-phosphate + NADP(+) => 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + 2 H(+)


name: MPI isomerises Fru6P to Man6P (Plasmodium falciparum)


name: RPE65 isomero-hydrolyses atREs to 11cROL (Mus musculus)


name: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + NADP(+) + H2O = 3-oxo-5,6-didehydrosuberyl-CoA + NADPH + 2 H(+)


name: RUNX1 binds the SOCS3 gene (Homo sapiens)


name: asc-C9-CoA + O2 <=> asc-DeltaC9-CoA + H2O2


name: 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol + 3'-phosphoadenylyl sulfate = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: SHP1 (PTPN6) binds JAK2 in the receptor complex (Homo sapiens)


name: deoxycholoyl-CoA + NAD(+) => 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NADH + H(+)


name: carnitine O-acetyltransferase II activity


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)


name: Defective SLC2A9 does not transport Fru, Glc, urate (Homo sapiens)


name: 19-(4-hydroxyphenyl)nonadecanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP => 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: Iodide is taken up by thyroid epithelial cells (Drosophila melanogaster)


name: (9Z,12Z,15Z)-hexadecatrienoyl-CoA + A + 2 H2O => (9Z,12Z)-hexadecadienoyl-CoA + AH2 + O2


name: 2,4-dienoyl-CoA reductase (NADPH) activity


name: 8-methylmenaquinone-6 + succinate = 8-methylmenaquinol-6 + fumarate


name: a beta-D-GalNAc-(1->4)-alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer + UDP + H(+) => a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine


name: a long-chain fatty aldehyde + 2 NADPH + O2 + H(+) => a long-chain alkane + formate + 2 NADP(+) + H2O


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)


name: sn-glycerol 3-phosphate + UDP-alpha-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + UDP + H(+)


name: PA is converted to CDP-DAG by CDS2 (Bos taurus)


name: CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Mus musculus)


name: TAS1R2:TAS1R3:sweet compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R2:TAS1R3:sweet compound, GNAT3:GTP, and GNB1,3:GNG13 (Homo sapiens)


name: 1-chloro-3-nitrobenzene + NADH + O2 <=> 4-chlorocatechol + nitrite + NAD(+)


name: Transport of MHC heterotrimer to ER exit site (Mus musculus)


name: 6,8-dihydroxypurine + O2 + H2O => urate + H2O2


name: lupanine + 2 Fe(III)-[cytochrome c] + H2O = 17-hydroxylupanine + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: "lupanine 17-hydroxylase (cytochrome c)"


name: taurodeoxycholate + 3'-phosphoadenylyl sulfate = 3alpha-sulfotaurodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: inhibition of protein-pyridoxal-5-phosphate linkage


name: FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors (Homo sapiens)


name: 3-deoxy-D-pentulosonic acid aldolase activity


name: pyruvate oxidase (CoA-acetylating) activity


name: Active MTORC1 binds the ULK1 complex (Gallus gallus)


name: a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol


name: 3-oxo-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADPH + H(+) = (3R)-hydroxy-(8Z,11Z,14Z,17Z,20Z,23Z)-hexacosahexaenoyl-CoA + NADP(+)


name: IC-asc-C7-CoA + O2 = IC-asc-DeltaC7-CoA + H2O2


name: tylactone + dTDP-alpha-D-mycaminose => 5-O-beta-D-mycaminosyltylactone + dTDP + H(+)


name: CEBPA binds CDK2 (Drosophila melanogaster)


name: glycyl-L-histidine + H2O => L-histidine + glycine


name: (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + NADP(+) => (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + NADPH + H(+)


name: a menaquinol + nitrate + 2 H(+)(in) = a menaquinone + nitrite + H2O + 2 H(+)(out)


name: NANP dephosphorylates Neu5Ac-9-P to Neu5Ac (Xenopus tropicalis)


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Xenopus tropicalis)


name: (1S,2R,4S)-borneol + NAD(+) <=> (1S,4S)-camphor + NADH + H(+)


name: delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside + UDP-alpha-D-glucose <=> delphinidin 3-O-(6''-O-malonyl)-beta-D-glucoside-3'-O-beta-D-glucoside + UDP


name: PCho and CTP are condensed to CDP-Cho by PCYT1 dimer (Drosophila melanogaster)


name: mevalonate transmembrane transporter activity


name: oxo-taxadiene-4alpha-ol + reduced [NADPH--hemoprotein reductase] + O2 = oxo-taxadiene-4alpha,9alpha-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: TBC1D16 accelerates GTP hydrolysis by RAB4A (Drosophila melanogaster)


name: molybdenum cofactor sulfurtransferase activity


name: PNPLA5 hydrolyzes TAG (Drosophila melanogaster)


name: HLCS biotinylates PC:Mn2+ (Canis familiaris)


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Rattus norvegicus)


name: MAP2K6 phosphorylates PIP4K2B (Xenopus tropicalis)


name: EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Rattus norvegicus)


name: Activated FGFR1:p-SHC1 binds GRB2:SOS1 (Canis familiaris)


name: Addition of nucleotides between position +11 and +30 (Homo sapiens)


name: PRDX1 overoxidizes (Drosophila melanogaster)


name: CYP27A1 27-hydroxylates 5β-CHOL3α,7α,24(s)-triol (Sus scrofa)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O <=> a 5'-end phospho-guanosine in mRNA + N(7)-methyl-GDP + 2 H(+)


name: (9Z,12Z,15Z)-octadecatrienoate + O2 = (11R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate


name: Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Xenopus tropicalis)


name: sulfate adenylyltransferase (ATP) activity


name: Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Homo sapiens)


name: Transfer of ubiquitin from E1 to E2 (Gallus gallus)


name: (S)-lactate + NAD(+) <=> pyruvate + NADH + H(+)


name: FLIP(L) and procaspase-8 form heterodimer (Mus musculus)


name: NEIL1 cleaves thymine glycol from damaged DNA (Canis familiaris)


name: L-phenylalanyl-L-phenylalanine(out) + H(+)(out) = L-phenylalanyl-L-phenylalanine(in) + H(+)(in)


name: NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Canis familiaris)


name: L-isoleucine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (1E,2S)-2-methylbutanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)


name: sCD163 binds MYH9 in T-cells (Homo sapiens)


name: 2'-deoxyuridine + 2-oxoglutarate + O2 => 2-deoxy-D-ribono-1,4-lactone + uracil + succinate + CO2


name: STARD10 binds LPCAT1 and PC (Sus scrofa)


name: p-S MAPK6,4 phosphorylate MAPKAPK5 (Sus scrofa)


name: 2-oxospirilloxanthin + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) = 2,2'-dioxospirilloxanthin + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O


name: 17beta-hydroxy-5beta-androst-1-en-3-one + NADP(+) => 17beta-hydroxyandrosta-1,4-dien-3-one + NADPH + H(+)


name: dalnigrein beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside + H2O = dalnigrein + beta-D-apiofuranosyl-(1->6)-D-glucopyranose + H(+)


name: 4 PBGs bind to form HMB (Xenopus tropicalis)


name: RAS GEFs promote RAS nucleotide exchange (Gallus gallus)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Danio rerio)


name: SLC7A1 (CAT-1)-mediated uptake of cationic amino acids (Bos taurus)


name: hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 7 (S)-methylmalonyl-CoA + 14 NADPH + 21 H(+) => C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 7 CO2 + 14 NADP(+) + 7 CoA + 7 H2O


name: (deoxy)nucleoside phosphate kinase activity, dTTP as phosphate donor


name: dTTP + a 2'-deoxyribonucleoside 5'-phosphate = a 2'-deoxyribonucleoside 5'-diphosphate + dTDP


name: a [peptide]-C-terminal (2S)-2-hydroxyglycine => a [peptide]-C-terminal amide + glyoxylate


name: dihydropyridine-sensitive calcium channel activity


name: heteropyrithiamine + 5-(2-hydroxyethyl)-4-methylthiazole => pyridine + thiamine


name: a menaquinone + succinate + 2 H(+)(out) <=> a menaquinol + fumarate + 2 H(+)(in)


name: FGFRL1 dimer binds FGFs (Canis familiaris)


name: an acyl-CoA + L-lysyl-[protein] => N(6)-acyl-L-lysyl-[protein] + CoA + H(+)


name: p-S-ITGA5:ITGB1 binds p-S373-GJA1 (Homo sapiens)


name: N-hexacosanoyl-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: a uridine in rRNA = a pseudouridine in rRNA


name: N-all-trans-retinylidenephosphatidylethanolamine(out) + ATP + H2O => N-all-trans-retinylidenephosphatidylethanolamine(in) + ADP + phosphate + H(+)


name: IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Gallus gallus)


name: TRPC3 gene transcription is stimulated by MECP2 (Homo sapiens)


name: Caspase-8 and FLIP(L) processing at TNFR signaling complex (Sus scrofa)


name: 2-oxo-2H-pyran-4,6-dicarboxylate + H2O = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(+)


name: SCD desaturates ST-CoA to OLE-CoA (Dictyostelium discoideum)


name: (4R)-hydroxysphinganine + octadecanoate => N-octadecanoyl-(4R)-hydroxysphinganine + H2O


name: oxidoreductase activity, acting on peroxide as acceptor


name: MRN complex binds shortened telomeres (Drosophila melanogaster)


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Bos taurus)


name: PTP-RO interacts with p-c-Kit complex (Mus musculus)


name: ABHD6,12 hydrolyse 3AG (Saccharomyces cerevisiae)


name: (E)-sinapate + UDP-alpha-D-glucose = 4-O-(beta-D-glucosyl)-trans-sinapate + UDP + H(+)


name: L-asparaginyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 => (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + succinate + CO2


name: long-chain fatty acid--protein ligase activity


name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Mus musculus)


name: ICMT methylates S-Farn RAS proteins (Gallus gallus)


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Rattus norvegicus)


name: propanoate(out) + 2 Na(+)(out) <=> propanoate(in) + 2 Na(+)(in)


name: AMP + ATP = adenosine 3'-diphosphate,5'-phosphate + AMP + H(+)


name: 3-demethylubiquinol-7 + S-adenosyl-L-methionine <=> ubiquinol-7 + S-adenosyl-L-homocysteine + H(+)


name: medicarpin + H2O <=> 4'-methoxyisoflavan-2',4,7-triol


name: p-S295-PDE3B hydrolyses cAMP to AMP (Dictyostelium discoideum)


name: Phosphorylation of Platelet Sec-1 (Drosophila melanogaster)


name: 2-(acylamino)ethyl fatty acid + a monoacyl-sn-glycero-3-phosphocholine => an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Drosophila melanogaster)


name: MK2 phosphorylates BRF1 (Rattus norvegicus)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Canis familiaris)


name: [methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase


name: AFG3L2 degrades mitochondrial inner membrane proteins (Gallus gallus)


name: PLA1A hydrolyses PS to 2-acyl LPS (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 => (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: methotrexate(in) + ATP + H2O <=> methotrexate(out) + ADP + phosphate + H(+)


name: nonanal + NAD(+) + H2O => nonanoate + NADH + 2 H(+)


name: DOLK phosphorylates DCHOL to DOLP (Dictyostelium discoideum)


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1->4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)


name: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + NADH + H(+)


name: PG is hydrolyzed to 1-acyl LPG by PLA2[16] (Sus scrofa)


name: F- and N- BAR domain proteins bind the clathrin-coated pit (Bos taurus)


name: 3-ketohexacosanoyl-CoA + CoASH => tetracosanoyl-CoA + acetyl-CoA (Homo sapiens)


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Canis familiaris)


name: 3-aminobutan-2-ol + NADP(+) + H2O <=> acetoin + NH4(+) + NADPH + H(+)


name: hydrolase activity, acting on acid phosphorus-nitrogen bonds


name: beta-cubebene + diphosphate => (2E,6E)-farnesyl diphosphate


name: PNP trimer transforms RBV to T-CONH2 (Canis familiaris)


name: PANK4 hydrolyzes PPANT to pantetheine (Mus musculus)


name: NBR1 binds MAP1LC3B (Dictyostelium discoideum)


name: FXN:NFS1:ISD11:ISCU assembles 2Fe-2S iron-sulfur cluster (Xenopus tropicalis)


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + (9Z)-octadecenoyl-CoA => 1-(9Z,12Z,15Z-octadecatrienoyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: ATP-dependent release of CDT1 from the OCCM complex (Homo sapiens)


name: ADP(in) + phosphate(out) + H(+)(in) => ADP(out) + phosphate(in) + H(+)(out)


name: N-terminal N(alpha)-acetyl-L-methionyl-L-glutaminyl-[protein] + CoA + H(+) => N-terminal L-methionyl-L-glutaminyl-[protein] + acetyl-CoA


name: an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate <=> an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)


name: SLC5A6 transports vitamins from extracellular region to cytosol (Sus scrofa)


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + ATP => beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + ADP


name: RAC1 and CDC42 activate PAK3 (Homo sapiens)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 = N-(11,12-epoxy-5Z,8Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: pelargonidin 3-O-(6-O-[(E)-caffeoyl]-beta-D-glucoside) 5-O-beta-D-glucoside + malonyl-CoA = 4'''-demalonylsalvianin + CoA


name: activation of uridine diphosphoglucuronate-bilirubin glucuronoside glucuronosyltransferase activity


name: ACAA2 tetramer transfers acyl group from Ac-CoA to acyl-CoA forming 3OA-CoA and CoA-SH (Rattus norvegicus)


name: MDH2 dimer dehydrogenates MAL (Schizosaccharomyces pombe)


name: GAPDH tetramers reduce 1,3BPG to GA3P (Xenopus tropicalis)


name: XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Caenorhabditis elegans)


name: I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Drosophila melanogaster)


name: 19-(4-hydroxyphenyl)nonadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2 + H2O <=> (1-deoxy-D-fructos-1-yl)amine + glyoxylate + H2O2


name: a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 = a (8S,9R)-5-glyceryl-2'-deoxycytidine in DNA + glyoxylate + CO2


name: SALM2 associate with AMPA and NMDA receptors (Danio rerio)


name: 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-hexadecenoyl-CoA


name: SYK is a substrate for JAK1 (Mus musculus)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP + H(+) => a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine + UDP-alpha-D-galactose


name: (5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)


name: pelargonidin + UDP-alpha-D-glucose = pelargonidin 3-O-beta-D-glucoside + UDP


name: [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine => pyridinium-3,5-bisthiocarboxylate mononucleotide + [LarE protein]-dehydroalanine + H(+)


name: a sphingomyelin(in) + ATP + H2O = a sphingomyelin(out) + ADP + phosphate + H(+)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA => 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA


name: CYP3A4, CYP2B6 bind ritonavir (Bos taurus)


name: 7-epi-cylindrospermopsin + succinate + CO2 => 7-deoxycylindrospermopsin + 2-oxoglutarate + O2


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O <=> a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: 3-(2,3-dihydroxyphenyl)propanoate + NAD(+) + H2O => 3-(3-hydroxyphenyl)propanoate + NADH + O2 + H(+)


name: dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate


name: 10-oxooctadecanoate + NADH + H(+) = 10-hydroxyoctadecanoate + NAD(+)


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Dictyostelium discoideum)


name: (S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 <=> 2,4-dichlorophenol + pyruvate + succinate + CO2


name: Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Bos taurus)


name: oxidoreductase activity, acting on diphenols and related substances as donors


name: "Acting on diphenols and related substances as donors"


name: Autoglucosylation of GYG1 complexed with GYS1-a (Rattus norvegicus)


name: beta-alanine + CO2 => L-aspartate + H(+)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Sus scrofa)


name: 2-nitroimidazole + H2O = 1,3-dihydro-2H-imidazol-2-one + nitrite + H(+)


name: SULT1A1 dimer sulfonates NHABP (Danio rerio)


name: an N-acyl-D-glutamate + H2O <=> D-glutamate + a carboxylate


name: Binding of acetylcholine to highly calcium permeable acetylcholine receptors (Sus scrofa)


name: guanosine 3',5'-bis(diphosphate) + phosphate + H(+) => guanosine 3'-diphosphate 5'-triphosphate + H2O


name: tRNA(Sec) + L-serine + ATP = L-seryl-tRNA(Sec) + AMP + diphosphate + H(+)


name: L-galactono-1,4-lactone + H2O = L-galactonate + H(+)


name: NEU2 hydrolyzes Neu5Ac from glycoconjugates (Homo sapiens)


name: RHOD binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Homo sapiens)


name: an (E)-omega-(methylsulfanyl)-alkanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+) => an L-polyhomomethionine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2


name: C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Drosophila melanogaster)


name: NRXNs bind CASK:Protein 4.1 (Rattus norvegicus)


name: glyceraldehyde 3-phosphate:phosphate antiporter activity


name: a ceramide(in) + ATP + H2O => a ceramide(out) + ADP + phosphate + H(+)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + all-trans-retinol => all-trans-retinyl 9Z-octadecenoate + di-(9Z)-octadecenoylglycerol


name: PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Rattus norvegicus)


name: alpha,alpha-trehalose + phosphate <=> beta-D-glucose 1-phosphate + D-glucose


name: an (R)-2-haloacid + H2O => a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenamide + H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoate + NH4(+)


name: 10-hydroperoxy-(8E)-octadecenoate => (9Z)-octadecenoate + O2


name: PIAS2,3,4 SUMOylate RORA with SUMO1 (Caenorhabditis elegans)


name: Factor D cleaves C3b-bound Factor B (Homo sapiens)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate


name: HTRA2 binds NDUFA13 (GRIM-19) (Bos taurus)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Homo sapiens)


name: Active G alpha (q) binds RGS proteins (Sus scrofa)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: formate(out) + chloride(in) => formate(in) + chloride(out)


name: p-Y-STAT3 and p-STAT5 dissociates from IL15:IL15RA:IL2RB:p-JAK1:IL2RG:p-JAK3:p-Y-STAT3:p-STAT5 (Sus scrofa)


name: octadecan-1-ol + NADP(+) <=> octadecanal + NADPH + H(+)


name: an N-(acyl)-sphingosylphosphocholine(in) = an N-(acyl)-sphingosylphosphocholine(out)


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Gallus gallus)


name: JNK phosphorylates BIM, BAD and other targets (Bos taurus)


name: [eIF5A protein]-deoxyhypusine + AH2 + O2 <=> [eIF5A protein]-hypusine + A + H2O


name: Association of GABA B receptor with G protein beta-gamma subunits (Bos taurus)


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Drosophila melanogaster)


name: mTORC2 phosphorylates AKT1 on serine-473 (Homo sapiens)


name: CDK1:CCNB phosphorylates NEK9 (Gallus gallus)


name: beta-alanine + L-arginine <=> 3-guanidinopropanoate + L-ornithine


name: PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Mus musculus)


name: RUNX2:CBFB binds the ITGA5 gene promoter (Homo sapiens)


name: PRLR binds SCF beta-TrCP complex (Homo sapiens)


name: Adhesion of integrin αIIbβ3 to fibrin network (Sus scrofa)


name: LTBP4 binds TGF-Beta-1 (Rattus norvegicus)


name: (d)GMP or (d)IMP + H2O => (2'-deoxy)guanosine or (2'-deoxy)inosine + orthophosphate (NT5C2) (Xenopus tropicalis)


name: [(1->4)-beta-D-glucosyl](n+1) + GDP + H(+) => [(1->4)-beta-D-glucosyl](n) + GDP-alpha-D-glucose


name: NIK autophosphorylates on T559 (Mus musculus)


name: DHAP is converted to G3P by GPD1/GPD1L (Rattus norvegicus)


name: PC is hydrolyzed to PA and choline by PLD1/2 (Canis familiaris)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Rattus norvegicus)


name: Furin cleaves pro-factor IX to factor IX (Rattus norvegicus)


name: glutaryl-CoA + H2O => glutarate + CoA + H(+)


name: core promoter sequence-specific DNA binding


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Drosophila melanogaster)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Xenopus tropicalis)


name: G-protein alpha releases G-protein heterotrimer from PDCL  (Gallus gallus)


name: Cleavage of uracil by UNG glycosylase (Canis familiaris)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: 3',5'-nucleotide bisphosphate phosphatase activity


name: proteasome-nuclear membrane anchor activity


name: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O <=> 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + sulfate + H(+)


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Caenorhabditis elegans)


name: proton-transporting ATPase activity, rotational mechanism


name: Association of the XRCC4:DNA ligase IV complex with the DNA-PK:DNA synaptic complex (Gallus gallus)


name: Collagen prolyl 3-hydroxylase converts 4-Hyp collagen to 3,4-Hyp collagen (Homo sapiens)


name: Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Drosophila melanogaster)


name: limit dextrin-glycogenin => ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl) glycogenin (Drosophila melanogaster)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + octadecanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-octadecanoyl-sn-glycerol + CoA


name: NIK autophosphorylates on T559 (Bos taurus)


name: Activated FGFR4 binds FRS2 (Gallus gallus)


name: EP3 receptor can bind PGE2 (Drosophila melanogaster)


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Rattus norvegicus)


name: apigenin 7-O-beta-D-glucoside + H2O => apigenin + beta-D-glucose


name: L-glutamate + NAD(+) + H2O = 2-oxoglutarate + NH4(+) + NADH + H(+)


name: (R)-3-(indol-3-yl)-2-oxobutanoate + S-adenosyl-L-homocysteine + H(+) => indole-3-pyruvate + S-adenosyl-L-methionine


name: dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)


name: a uridine in RNA + S-adenosyl-L-methionine <=> a 5-methyluridine in RNA + S-adenosyl-L-homocysteine + H(+)


name: 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H(+) => 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: 2-oxo-3-sulfanylpropanoate + [thioredoxin]-dithiol => [thioredoxin]-disulfide + hydrogen sulfide + pyruvate + H(+)


name: (14R,15R)-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate => (14S,15R)-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O


name: ADRB2 in ADRB2:GRK complex is phosphorylated (Gallus gallus)


name: SAICAR => AICAR + Fumarate (Saccharomyces cerevisiae)


name: deacetylcephalosporin C + succinate + CO2 => deacetoxycephalosporin C + 2-oxoglutarate + O2


name: CDKN1B gene expression is stimulated by FOXO1,FOXO3,FOXO4 (Homo sapiens)


name: ME2 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)


name: Nef Binds and activates the Src-family tyrosine kinase Lck (Homo sapiens)


name: 2 leukotriene A4 + O2 + 2 H2O = 2 lipoxin A4


name: Delta(1)-piperideine-2-carboxylate + H2O => 6-amino-2-oxohexanoate


name: RHOA:GTP binds ROCK, activating it (Canis familiaris)


name: pheophorbide a + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> red chlorophyll catabolite + 2 oxidized [2Fe-2S]-[ferredoxin]


name: hyocholate + UDP-alpha-D-glucuronate => hyocholate 6-O-(beta-D-glucuronate) + UDP + H(+)


name: prostaglandin E1(in) + ATP + H2O => prostaglandin E1(out) + ADP + phosphate + H(+)


name: 4-carboxycholesta-8(9),24-dien-3beta-ol is decarboxylated and oxidized to form cholesta-8(9),24-dien-3-one (zymosterone) (Dictyostelium discoideum)


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Homo sapiens)


name: Thyroxine is deiodinated to triiodothyronine (Sus scrofa)


name: CatSper Channel Mediated Calcium Transport (Canis familiaris)


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Plasmodium falciparum)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: L-lysyl-[protein] + 3 S-adenosyl-L-methionine => N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: (10E)-octadecenoate + H2O <=> 10-hydroxyoctadecanoate


name: 24,25-dihydrolanosterol + reduced [NADPH--hemoprotein reductase] + O2 => 32-hydroxy-24,25-dihydrolanosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: MAP2K2 binds MAPK1 (Dictyostelium discoideum)


name: [calmodulin]-L-lysine + S-adenosyl-L-methionine = [calmodulin]-N(6)-methyl-L-lysine + S-adenosyl-L-homocysteine + H(+)


name: 3,3',5-triiodo-L-thyronine(out) + L-glutamate(in) <=> 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out)


name: (1S,2S,4R)-endo-fenchol + diphosphate => (2E)-geranyl diphosphate + H2O


name: dihydrorhizobitoxine + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> rhizobitoxine + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: EGR2 (KROX20) activates HOXB2 expression (Homo sapiens)


name: Mig-2 recruits Migfilin to the cell-ECM adhesions (Drosophila melanogaster)


name: CTNNB1 T41 mutants aren't phosphorylated by GSK3beta (Homo sapiens)


name: glycolytic process via Entner-Doudoroff Pathway


name: COQ2 ligates all-E-10PrP2 to PHB (Danio rerio)


name: 22-oxodocosanoate + reduced [NADPH--hemoprotein reductase] + O2 <=> docosanedioate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: GGT dimers hydrolyse APAP-SG (Canis familiaris)


name: Release of E3 from polyubiquitinated substrate (Plasmodium falciparum)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)


name: squalene + 2 diphosphate + NAD(+) => 2 (2E,6E)-farnesyl diphosphate + NADH + H(+)


name: 4-pyridoxolactone + H2O = 4-pyridoxate + H(+)


name: abieta-7,13-dien-18-al + NAD(+) + H2O <=> abieta-7,13-dien-18-oate + NADH + 2 H(+)


name: 2',3'-cyclophospho-CMP + H2O = cytidine 2'-phosphate + H(+)


name: (2R)-2-O-(6-phospho-alpha-D-mannosyl)-glycerate(in) + L-histidyl-[protein] => (2R)-2-O-(alpha-D-mannosyl)-glycerate(out) + N(pros)-phospho-L-histidyl-[protein]


name: Conversion of C2 into C2a and C2b (Canis familiaris)


name: Competitive inhibition of translation initiation by ISGylated 4EHP (Drosophila melanogaster)


name: (2E)-geranial + NADH + H(+) => (2E)-geraniol + NAD(+)


name: nor-toralactone + S-adenosyl-L-methionine = toralactone + S-adenosyl-L-homocysteine + H(+)


name: 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(out) + glutarate(in) <=> 5alpha-androstane-3alpha,17beta-diol 3-O-(beta-D-glucuronate)(in) + glutarate(out)


name: tetradecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> (9Z)-tetradecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: PKC phosphorylates NCF1 (Saccharomyces cerevisiae)


name: 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA <=> 1,2-di-(9Z-octadecenoyl)-glycerol + CoA


name: mitochondrial RNA polymerase regulatory region sequence-specific DNA binding


name: positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator


name: regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity


name: (R)-epichlorohydrin + H2O <=> (R)-3-chloro-1,2-propanediol


name: sn-glycerol 3-phosphocholine + a fatty acid + H(+) => a 2-acyl-sn-glycero-3-phosphocholine + H2O


name: an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+) => a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O


name: PRLR is phosphorylated at Ser-349 (Xenopus tropicalis)


name: RHOBTB1 binds interacting proteins at the endosome membrane (Dictyostelium discoideum)


name: Cytosolic H2O2 decarboxylates PYR to acetate (Homo sapiens)


name: Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Xenopus tropicalis)


name: an N-(36-hydroxyhexatriacontadienoyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol = an N-(36-(9Z,12Z-octadecadienoyloxy)-hexatriacontadienoyl)-sphing-4-enine + a diacylglycerol


name: a ganglioside GD1b (d18:1(4E)) + H2O <=> a ganglioside GM1 (d18:1(4E)) + N-acetylneuraminate


name: 2''-O-octanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein] => N(6)-octanoyl-L-lysyl-[protein] + NAD(+) + H2O


name: Cis-Heterodimerization of nephrin and KIRREL (Mus musculus)


name: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose => 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose + H(+)


name: ROCK1,ROCK2 are activated (Rattus norvegicus)


name: UDP-2-acetamido-2-deoxy-alpha-D-glucuronate + NAD(+) = UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + NADH + H(+)


name: Thyrotropin is a heterodimer (Bos taurus)


name: a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + a fatty acid + H(+)


name: structural constituent of synapse-associated extracellular matrix


name: a 1-[(9Z,12Z)-octadecdienoyl]-2-acyl-glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> a 1-[(9Z,12Z,15Z)-octadectrienoyl]-2-acyl-glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: Collagen type VII binds integrin alpha2beta1 (Caenorhabditis elegans)


name: beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxy-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: GUSB tetramer hydrolyses (HA)2 (Homo sapiens)


name: C3 convertases spontaneously dissociate (Sus scrofa)


name: Isomerization of (2R)-pristanoyl-CoA to (2S)-pristanoyl-CoA (Danio rerio)


name: (E)-feruloylacetyl-CoA + (E)-4-coumaroyl-CoA + H2O => demethoxycurcumin + CO2 + 2 CoA


name: AMP(out) + phosphate(in) <=> AMP(in) + phosphate(out)


name: Class IV antihypertensives bind LTCC multimer (Rattus norvegicus)


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Drosophila melanogaster)


name: isorhamnetin + S-adenosyl-L-methionine = 3',4'-O-dimethylquercetin + S-adenosyl-L-homocysteine + 2 H(+)


name: Basigin binds Mannose-carrying cell recognition molecules (Rattus norvegicus)


name: a quinone + succinate = fumarate + a quinol


name: N(omega),N(omega)-dimethyl-L-arginine + pyruvate <=> 5-(3,3-dimethylguanidino)-2-oxopentanoate + L-alanine


name: ARL2:GTP bind PDE6D on KRAS4B (Sus scrofa)


name: (1S,4R)-isodihydrocarvone + NADPH + O2 + H(+) <=> (3S,6R)-6-isopropenyl-3-methyloxepan-2-one + NADP(+) + H2O


name: anthraniloyl-CoA + malonyl-CoA + H(+) <=> (2-aminobenzoyl)acetyl-CoA + CO2 + CoA


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Canis familiaris)


name: HSD17B13 binds lipid droplets (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine(out) => a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in)


name: L-tyrosyl-[protein] + NAD(+) = O-(ADP-D-ribosyl)-L-tyrosyl-[protein] + nicotinamide + H(+)


name: SLMB binds to and ubiquitinates phosphorylated CI (Drosophila melanogaster)


name: PIAS1 SUMOylates SP3 with SUMO1 (Sus scrofa)


name: peroxisome membrane class-2 targeting sequence binding


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Bos taurus)


name: [thioredoxin]-dithiol + GDP => dGDP + [thioredoxin]-disulfide + H2O


name: peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine


name: (S)-cis-N-methyltetrahydropalmatine + reduced [NADPH--hemoprotein reductase] + O2 = muramine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: ALG9 transfers Man to N-glycan precursor (GlcNAc)2 (Man)8 (PP-Dol)1 (Gallus gallus)


name: GluN1 (GRIN1) binds to NEFL at postsynaptic density (Homo sapiens)


name: D-tryptophan(in) + chloride(in) + 2 Na(+)(in) => D-tryptophan(out) + chloride(out) + 2 Na(+)(out)


name: L-pipecolate(out) + chloride(out) + 2 Na(+)(out) <=> L-pipecolate(in) + chloride(in) + 2 Na(+)(in)


name: UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Plasmodium falciparum)


name: botC:GT1b internalized from target cell plasma membrane to synaptic vesicle membrane (Homo sapiens)


name: ursodeoxycholoyl-CoA + lithocholate => ursodeoxycholate + lithocholoyl-CoA


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Caenorhabditis elegans)


name: negative regulation of homocysteine metabolic process


name: Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)


name: formaldehyde + H2O2 + NH4(+) => methylamine + O2 + H2O


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Schizosaccharomyces pombe)


name: 3-methyl-2-oxobutanoate + H2O => 2,3-dihydroxy-3-methylbutanoate


name: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate


name: DPP4(1-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Sus scrofa)


name: The Interleukin 1 receptor complex binds Tollip (Canis familiaris)


name: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: NGEF exchanges GTP for GDP on RHOA (Caenorhabditis elegans)


name: pppA(2'-5')pG + diphosphate => GTP + ATP


name: L-seryl-[protein] + dodecanoyl-CoA <=> O-dodecanoyl-L-seryl-[protein] + CoA


name: CBX4 (Pc2) SUMOylates CETN2 with SUMO2,3 (Sus scrofa)


name: acetoacetyl-CoA + acetyl-CoA + H2O = (3S)-hydroxy-3-methylglutaryl-CoA + CoA + H(+)


name: Fibrillin microfibril assembly (Dictyostelium discoideum)


name: Transfer of SUMO1 from E1 to UBE2I (UBC9) (Bos taurus)


name: Exchange of palmitoylcarnitine and carnitine across the inner mitochondrial membrane (Drosophila melanogaster)


name: p38 MAPK activation by VEGFR (Gallus gallus)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Caenorhabditis elegans)


name: a beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc4Cer(d18:1(4E)) + UDP + H(+)


name: 3-O-(N-acetyl-beta-D-glucosaminyl)-L-seryl-[protein] + H2O => N-acetyl-D-glucosamine + L-seryl-[protein]


name: anhydrotetracycline + NADPH + O2 + H(+) = 5a,11a-dehydrotetracycline + NADP(+) + H2O


name: a 1,2-diacyl-sn-glycero-3-phosphate + a 1-acyl-sn-glycero-3-phosphocholine => a 1-acyl-sn-glycero-3-phosphate + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + H2O + H(+) <=> Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + N-(2,3-dihydroxybenzoyl)-L-serine


name: 2-oxohexanoate + L-kynurenine = L-2-aminohexanoate + kynurenate + H2O


name: ERCC2-facilitated RNA Pol II backtracking in TC-NER (Saccharomyces cerevisiae)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O = 14betaH-scalarane-17alpha-19-diol


name: Translocation of p-STAT1:p-STAT1 dimer to nucleus (Canis familiaris)


name: DDX5 binds ESR1:estrogen:TFF1 gene promoter (Sus scrofa)


name: perillyl aldehyde + NADP(+) + H2O <=> perillate + NADPH + 2 H(+)


name: SSBP1 binds the displaced parental H strand (Homo sapiens)


name: GSTK1 dimer transfers GS from GSH to CDNB (Canis familiaris)


name: alpha-aminoadipoate semialdehyde + NAD+ => alpha-aminoadipate + NADH + H+ (Bos taurus)


name: Annealing of 3'-end of unwound transfer RNA primer with genomic RNA (Homo sapiens)


name: Translocation of RIAM to plasma membrane (Mus musculus)


name: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + H2O = 2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + UDP + H(+)


name: OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA (Homo sapiens)


name: HRH4 binds Hist (Drosophila melanogaster)


name: a sterol ester + H2O = a sterol + a fatty acid + H(+)


name: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O <=> 2 ADP + 2 H(+)


name: (3R)-1,4-thiomorpholine-3-carboxylate + NADP(+) = 3,4-dehydrothiomorpholine-3-carboxylate + NADPH + 2 H(+)


name: PAK binds RAC and bPIX (Caenorhabditis elegans)


name: 7-deoxyloganin + reduced [NADPH--hemoprotein reductase] + O2 <=> loganin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: an N-acylneuraminate 9-phosphate + H2O <=> an N-acylneuraminate + phosphate


name: NK13650 B + S-adenosyl-L-methionine => NK13650 D + S-adenosyl-L-homocysteine + H(+)


name: 6 malonyl-CoA + acetyl-CoA + 5 H(+) = 3,6,7,9-tetrahydroxy-3-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyran-1-one + 6 CO2 + 7 CoA + H2O


name: Beclin-1 complex translocates to the ER (Homo sapiens)


name: gamma-L-glutamyl-butirosin B <=> butirosin B + 5-oxo-L-proline


name: D-maltose + H2O = alpha-D-glucose + D-glucose


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O => 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+)


name: noradrenaline + acetyl-CoA => N-acetylnoradrenaline + CoA + H(+)


name: CARMA1 recruits MALT1 and BCL10 forming CBM Complex (Mus musculus)


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Sus scrofa)


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-glycerol <=> 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: a phenol + 3'-phosphoadenylyl sulfate = an aryl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + ATP + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + ADP + phosphate + H(+)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Xenopus tropicalis)


name: O-methyl-L-tyrosine + anthranilate + S-adenosyl-L-methionine + 2 ATP => (-)-4'-methoxycyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H(+)


name: eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Rattus norvegicus)


name: Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Gallus gallus)


name: 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H2O = alpha-D-mannose derivative + alpha-D-glucose 1-phosphate + H(+)


name: NCOA2(869-1464) binds KAT6A(1-1118) (Canis familiaris)


name: IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Sus scrofa)


name: sarcosine(out) + H(+)(out) => sarcosine(in) + H(+)(in)


name: WNT ligands traffic to the Golgi (Homo sapiens)


name: (4S)-4-hydroxy-2-oxoglutarate <=> glyoxylate + pyruvate


name: ROS oxidize thioredoxin and activate MAP3K5 (Saccharomyces cerevisiae)


name: 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O = methanol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)


name: 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Canis familiaris)


name: L-methionyl-[protein] + S-adenosyl-L-methionine => S-methyl-L-methionyl-[protein] + S-adenosyl-L-homocysteine


name: 2xPNPO:2xFMN oxidizes PXAP to PXLP (Mus musculus)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Canis familiaris)


name: p-T182 MAPKAPK5 phosphorylates FOXO1 (Bos taurus)


name: L-cystine(in) + ADP + phosphate + H(+) => L-cystine(out) + ATP + H2O


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Sus scrofa)


name: RAC2 translocates to the mitochondrial membrane (Drosophila melanogaster)


name: AKT phosphorylates CREB1 (Caenorhabditis elegans)


name: (2Z,6E)-farnesyl diphosphate = (-)-alpha-cedrene + diphosphate


name: STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Bos taurus)


name: TFAP2A homodimer binds the TGFA gene promoter (Homo sapiens)


name: MBTPS2 (S2P) cleaves ATF6B (ATF6-beta) (Sus scrofa)


name: formate acetyltransferase-glycine dihydroflavodoxin:S-adenosyl-L-methionine oxidoreductase (S-adenosyl-L-methionine cleaving) activity


name: Formation of hydroxyallysine by LOX (Canis familiaris)


name: dUMP(in) + CTP(out) <=> dUMP(out) + CTP(in)


name: C3a receptor binds anaphylatoxin C3a (Canis familiaris)


name: SARS-CoV-1 9b recruits ITCH to MAVS  (Homo sapiens)


name: PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)


name: NF-kappa-B complex is transported from cytosol to nucleus (Bos taurus)


name: cholesterol + NADPH + O2 + H(+) => 7-dehydrocholesterol + NADP(+) + 2 H2O


name: hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O => sulfite + 6 reduced [2Fe-2S]-[ferredoxin] + 7 H(+)


name: D-glyceraldehyde 3-phosphate + orthophosphate + NAD+ <=> 1,3-bisphospho-D-glycerate + NADH + H+ (Homo sapiens)


name: MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Danio rerio)


name: STARD7 transports Q10 to plasma membrane (Mus musculus)


name: 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate => 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + formate + ATP


name: "[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase"


name: RHOC activates endoplasmic reticulum effectors (Homo sapiens)


name: ERBB4s80:TAB2:NCOR1 complex translocates to the nucleus (Homo sapiens)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Schizosaccharomyces pombe)


name: nigerone + NADP(+) + 2 H2O => 2 rubrofusarin B + NADPH + O2 + 3 H(+)


name: L-adenosylselenomethionine + phosphate + diphosphate => L-selenomethionine + ATP + H2O


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Xenopus tropicalis)


name: LGI4 binds ADAM22,23,11 (Canis familiaris)


name: Release of SMAC (DIABLO) from mitochondria (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> germacrene C + diphosphate


name: (3R)-hydroxyoctanoyl-[ACP] + NADP(+) => 3-oxooctanoyl-[ACP] + NADPH + H(+)


name: a 3-oxo-Delta(4)-steroid => a 3-oxo-Delta(5)-steroid


name: Spherical HDL binds membrane-associated free cholesterol and phospholipids (Mus musculus)


name: hexanoyl-CoA + 3 malonyl-CoA + 3 H(+) => 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: Cross-linking of FCGRIA with IgG-coated Ag (Bos taurus)


name: DPEP hydrolyses MCTR2 to MCTR3 (Homo sapiens)


name: N-methyl-2-methylpropanamine + NAD(+) + H2O <=> 2-methylpropanal + methylamine + NADH + H(+)


name: Loading of GABA into clathrin sculpted GABA transport vesicle lumen (Gallus gallus)


name: The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus (Drosophila melanogaster)


name: Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)


name: 2 Co(II)-[methylamine-specific corrinoid protein] + AH2 + ATP + H2O = 2 Co(I)-[methylamine-specific corrinoid protein] + A + ADP + phosphate + 3 H(+)


name: 2-dehydro-3-deoxy-D-arabinonate + NAD(+) = 5-hydroxy-2,4-dioxopentanoate + NADH + H(+)


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Caenorhabditis elegans)


name: 3-phenylsuccinyl-CoA + succinate => phenylsuccinate + succinyl-CoA


name: prostaglandin D2 => prostaglandin J2 + H2O


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Homo sapiens)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Dictyostelium discoideum)


name: an N-(34-hydroxytetratriacontadienoyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol = an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontadienoyl)-sphing-4-enine + a diacylglycerol


name: glycine + ATP + H(+) = glycyl-5'-AMP + diphosphate


name: alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP-alpha-D-mannose = [alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n+1)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + 2 GDP + 2 H(+)


name: 12-hydroxydihydrochelirubine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => dihydrochelirubine + reduced [NADPH--hemoprotein reductase] + O2


name: 3,3'-diiodothyronine + PAPS => 3,3'-diiodothyronine 4-sulfate + PAP (Homo sapiens)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Drosophila melanogaster)


name: Importin-8 binds AGO2:miRNA (Rattus norvegicus)


name: alcohol dehydrogenase (cytochrome c) activity


name: galactose catabolic process via UDP-galactose


name: 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+) => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O


name: L-alanyl-L-glutamate(out) + H(+)(out) = L-alanyl-L-glutamate(in) + H(+)(in)


name: 4 2-aminophenol + 3 O2 = 2 2-aminophenoxazin-3-one + 6 H2O


name: RUNX1 and GATA1 bind the promoter of the ITGA2B gene (Homo sapiens)


name: isoquinoline + A + H2O <=> isoquinolin-1(2H)-one + AH2


name: an omega-oxo fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = a dicarboxylate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->8)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Mus musculus)


name: BSG:MCTs cotransport LACT, H+ from extracellular region to cytosol (Bos taurus)


name: Collagen type II binds integrin alpha10beta1 (Sus scrofa)


name: HP1 alpha binds Histone H3K9(me)3 (Rattus norvegicus)


name: Autophosphorylation of PAK1 (Caenorhabditis elegans)


name: N-terminal N,N-dimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-methionine <=> N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + S-adenosyl-L-homocysteine + H(+)


name: (+)-premalbrancheamide + bromide + FAD + 2 H(+) = (+)-isomalbrancheamide C + FADH2


name: Acireductone is oxidized to MOB (Mus musculus)


name: BLT receptors can bind LTB4 (Rattus norvegicus)


name: B4GAT1:GYLTL1B transfers GlcA from UDP-GlcA to Xyl-GlcA (Xenopus tropicalis)


name: 3-phosphonopyruvate + H(+) = phosphonoacetaldehyde + CO2


name: 3-methoxy-4',5-dihydroxy-trans-stilbene + S-adenosyl-L-methionine => pterostilbene + S-adenosyl-L-homocysteine + H(+)


name: p-Y701-STAT1, p-Y705-STAT3, p-Y649-STAT5 dissociates from IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:p-Y705-STAT3 (Sus scrofa)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Gallus gallus)


name: an N-methylornithine lipid + S-adenosyl-L-methionine => an N,N-dimethylornithine lipid + S-adenosyl-L-homocysteine + H(+)


name: a ribonucleoside + phosphate => a ribonucleoside 5'-phosphate + H2O


name: DELE1(143-515) is released into the cytosol (Sus scrofa)


name: spermine + L-glutamate + ATP => gamma-L-glutamylspermine + ADP + phosphate + H(+)


name: plasminogen:histidine-rich glycoprotein -> plasmin + histidine-rich glycoprotein (uPA [two-chain] catalyst) (Bos taurus)


name: SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Mus musculus)


name: 12-hexadecanoyloxy-octadecanoate + H2O = 12-hydroxyoctadecanoate + hexadecanoate + H(+)


name: O-ureido-D-serine + ATP + H2O + H(+) = D-cycloserine + NH4(+) + ADP + phosphate + CO2


name: L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-methionine <=> N(6)-methyl-L-lysyl(8)-[histone H2AZ] + S-adenosyl-L-homocysteine + H(+)


name: MET bound PI3K generates PIP3 (Homo sapiens)


name: 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH => 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NAD(+)


name: 17-beta-ketosteroid reductase (NADPH) activity


name: abacavir [extracellular] => abacavir [cytosol] (Gallus gallus)


name: ARL2:GTP bind PDE6D on KRAS4B (Canis familiaris)


name: (Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 <=> (-)-4'-methoxycyclopenine + succinate + CO2


name: L-threonyl-[myosin light chain] + ATP => O-phospho-L-threonyl-[myosin light chain] + ADP + H(+)


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Danio rerio)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Xenopus tropicalis)


name: N-acetyl-L-cysteine + A + H2O => N-acetyl-S-hydroxy-L-cysteine + AH2


name: 4-(hydroxyamino)quinoline N-oxide + 2 NADP(+) + H2O = 4-nitroquinoline N-oxide + 2 NADPH + 2 H(+)


name: (2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Dictyostelium discoideum)


name: Increased Parasympathetic Glutamate Activity


name: FUT3 transfers Fuc to Type 1 chains to form LeA (Sus scrofa)


name: L-lyxonate = 2-dehydro-3-deoxy-L-arabinonate + H2O


name: I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus (Canis familiaris)


name: dehydroepiandrosterone 3-sulfate(in) + butanoate(out) => dehydroepiandrosterone 3-sulfate(out) + butanoate(in)


name: androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (3Z)-hex-3-en-1-ol + acetyl-CoA <=> (3Z)-hex-3-en-1-yl acetate + CoA


name: (9Z)-hexadecenoate + 9-hydroxy-octadecanoate + H(+) => 9-(9Z-hexadecenoyloxy)-octadecanoate + H2O


name: GTP-dependent polynucleotide 5'-hydroxyl-kinase activity


name: dTDP-alpha-D-forosamine + S-adenosyl-L-homocysteine + H(+) => dTDP-4-(methylamino)-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose + S-adenosyl-L-methionine


name: 4-nitrobenzaldehyde + H2O2 => 4-nitrobenzyl alcohol + O2


name: phosphonoacetate + H2O => acetate + phosphate + H(+)


name: Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)


name: 3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)


name: IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Mus musculus)


name: SLC25A18,22 import L-Glu, H+ (Rattus norvegicus)


name: GDP-D-glucose + (2R)-3-phosphoglycerate = (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)


name: TRAF6 binds to p75NTR:NRIF (Homo sapiens)


name: blood platelet-activating factor acetyltransferase activity


name: at-retinyl is hydrolysed from p-MII:SAG to release atRAL (Sus scrofa)


name: (3R)-3-hydroxydecanoyl-CoA + NAD(+) = 3-oxodecanoyl-CoA + NADH + H(+)


name: formate + ATP + H(+) <=> dATP + CO2 + H2O


name: holo-[mycocerosate synthase] + a long-chain fatty acid + ATP <=> a long-chain fatty acyl-[mycocerosate synthase] + AMP + diphosphate


name: Mature NOTCH heterodimer traffics to the plasma membrane (Sus scrofa)


name: 6alpha-hydroxytyphasterol + reduced [NADPH--hemoprotein reductase] + O2 => typhasterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: BMX phosphorylates RUFY1 (Rattus norvegicus)


name: dTDP-beta-L-daunosamine + epsilon-rhodomycinone = rhodomycin D + dTDP + H(+)


name: cholesteryl (9Z-octadecenoate)(in) = cholesteryl (9Z-octadecenoate)(out)


name: dideacetyl astellolide B + acetyl-CoA = 14-deacetyl astellolide B + CoA


name: D-maltose + ATP => alpha-maltose 1-phosphate + ADP + H(+)


name: L-lysyl-tRNA(Lys) + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) <=> a 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys)


name: negative regulation of protein phosphorylation


name: STING recruits TBK1 and STAT6 (Homo sapiens)


name: SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling (Mus musculus)


name: Neuraminidase (NA) synthesis (Homo sapiens)


name: (2S)-naringenin + UDP-alpha-D-glucose <=> (2S)-naringenin 7-O-beta-D-glucoside + UDP + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: (5R)-5-O-(beta-D-galactosyl)-5-hydroxy-L-lysyl-[collagen] + D-glucose => (5R)-5-O-[alpha-D-glucosyl-(1->2)-beta-D-galactosyl]-5-hydroxy-L-lysyl-[collagen] + H2O


name: GDP-alpha-D-glucose + D-glucose 6-phosphate <=> alpha,alpha-trehalose 6-phosphate + GDP + H(+)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Canis familiaris)


name: GEFs activate RhoA,B,C (Xenopus tropicalis)


name: spermine dialdehyde => N-(4-aminobutyl)-3-aminopropanal + acrolein


name: chondroitin beta-D-glucuronate + n 3'-phosphoadenylyl sulfate = chondroitin 4'-sulfate + n adenosine 3',5'-bisphosphate + n H(+)


name: thiamine(out) + ATP + H2O <=> thiamine(in) + ADP + phosphate + H(+)


name: 6 reduced [adrenodoxin] + cholesterol + 3 O2 + 6 H(+) = 4-methylpentanal + pregnenolone + 6 oxidized [adrenodoxin] + 4 H2O


name: 4-hydroxy-4-methyl-2-oxoglutarate => 2 pyruvate


name: Adenylate cyclase increases the GTPase activity of Gi alpha (Dictyostelium discoideum)


name: (2S)-2-acetolactate + H(+) = (R)-acetoin + CO2


name: 7-oxolithocholate + NADPH + H(+) <=> ursodeoxycholate + NADP(+)


name: 3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + CTP = CMP-beta-3-deoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonate + diphosphate


name: EPM2A dimer binds PPP1R3C:phosphoglycogen-GYG2 complex (Homo sapiens)


name: Binding of SLBP to Replication-Dependent Histone Pre-mRNA (Caenorhabditis elegans)


name: N-deacetylisoipecoside + H2O = N-deacetylisoipecoside aglycone + D-glucose


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Sus scrofa)


name: 4 norrubrofusarin + O2 <=> 2 ustilaginoidin A + 2 H2O


name: L-glutamyl-[protein] + ADP-D-ribose + H(+) => 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + H2O


name: testosterone dehydrogenase (NAD+) activity


name: Defective SLC12A3 does not cotransport Cl-, Na+ from extracellular region to cytosol (Homo sapiens)


name: SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Danio rerio)


name: SHPRH polyubiquitinates monoubiquitinated PCNA (Gallus gallus)


name: DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA  (Rattus norvegicus)


name: beta-ketoacyl-acyl-carrier-protein synthase III activity


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Canis familiaris)


name: beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) (Xenopus tropicalis)


name: NOTCH precursor cleaved to form mature NOTCH (Xenopus tropicalis)


name: Trehalose-6-phosphate is hydrolyzed to trehalose (Mycobacterium tuberculosis)


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Caenorhabditis elegans)


name: 2-heptyl-4(1H)-quinolone + H2O => 1-(2-aminophenyl)decane-1,3-dione


name: MITF-M-dependent ATP6V0E1 gene expression (Homo sapiens)


name: UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Danio rerio)


name: (R)-canadine + 2 NADP(+) => berberine + 2 NADPH + H(+)


name: sphinganine + ATP = sphinganine 1-phosphate + ADP + H(+)


name: serotonin + acetate => N-acetylserotonin + H2O


name: asnovolin A + 2-oxoglutarate + 2 O2 = fumigatonoid A + succinate + CO2


name: protoporphyrin IX + 3 a menaquinol => protoporphyrinogen IX + 3 a menaquinone


name: 2-aminomalonate semialdehyde + H(+) <=> aminoacetaldehyde + CO2


name: Vamp2 associated secretory vesicle to plasma membrane transport (Drosophila melanogaster)


name: L-arginine + O2 + H2O => 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: RNase H-mediated degradation of the template strand (Homo sapiens)


name: a D-guloside + NAD(+) = a 3-dehydro-D-guloside + NADH + H(+)


name: positive regulation of protein-containing complex disassembly


name: Active LTK phosphorylates IRS1 (Gallus gallus)


name: GSK3B phosphorylates p-NFE2L2 (Canis familiaris)


name: PGE2 is converted to PGF2a by CBR1 (Rattus norvegicus)


name: histone H3K27me2/H3K27me3 demethylase activity


name: dehydroepiandrosterone 3-sulfate(in) + glutarate(out) => dehydroepiandrosterone 3-sulfate(out) + glutarate(in)


name: Thrombin-activated PARs activate G12/13 (Canis familiaris)


name: Gq activation by TP receptor (Rattus norvegicus)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Rattus norvegicus)


name: hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Homo sapiens)


name: CDP(in) + CTP(out) <=> CDP(out) + CTP(in)


name: SMO translocates to the cilium (Homo sapiens)


name: 2',3'-cGAMP(in) + ATP + H2O => 2',3'-cGAMP(out) + ADP + phosphate + H(+)


name: Translocation of PDK1 to Plasma membrane (Caenorhabditis elegans)


name: Association of Ku heterodimer with ends of DNA double-strand break (Mus musculus)


name: (R)-noradrenaline + S-adenosyl-L-methionine <=> (R)-normetanephrine + S-adenosyl-L-homocysteine + H(+)


name: inhibition of mucopeptide glucohydrolase activity


name: SUMF2 binds SUMF1, inhibiting SUMF1-mediated activation of arylsulfatases (Gallus gallus)


name: p-STAT3 dimerizes (Drosophila melanogaster)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Sus scrofa)


name: ALOX5 oxidises 5(S)-Hp-18(R)-HEPE to 5S,6S-epoxy-18(R)-HEPE (Xenopus tropicalis)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA <=> a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Gallus gallus)


name: a 5'-hydroxy-3'-methoxyflavone + S-adenosyl-L-methionine => a 3',5'-dimethoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: PRKCI phosphorylates NFE2L2 (Bos taurus)


name: (3R)-hydroxyoctanoyl-CoA + NADP(+) <=> 3-oxooctanoyl-CoA + NADPH + H(+)


name: SYVN1 ubiquitinates Hh C-terminal fragments (Homo sapiens)


name: 3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-methionine => N-methyl-3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Canis familiaris)


name: activation of beta-galactosidase activity


name: p-AMPK:AMP binds the ULK complex (Caenorhabditis elegans)


name: neurotensin(1-11) + L-isoleucyl-L-leucine => neurotensin + H2O


name: 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Saccharomyces cerevisiae)


name: Association of Nek2A with MCC:APC/C (Canis familiaris)


name: mevastatin + H2O <=> compactin diol lactone + (S)-2-methylbutanoate + H(+)


name: SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Bos taurus)


name: PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Saccharomyces cerevisiae)


name: luteolin 7-O-beta-D-glucuronide + UDP + H(+) => luteolin + UDP-alpha-D-glucuronate


name: 3-ethylmalate + CoA + H(+) => butanoyl-CoA + glyoxylate + H2O


name: (2E,6E)-farnesyl diphosphate = (1R,4R,5S)-acoradiene + diphosphate


name: SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Homo sapiens)


name: MAF1 translocates to the nucleus (Bos taurus)


name: MAP2Ks and MAPKs bind to the activated RAF complex (Sus scrofa)


name: AAC1 imports a proton (Dictyostelium discoideum)


name: 16alpha,17beta-estriol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+) => 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate


name: chorismate => 3-[(1-carboxyvinyl)-oxy]benzoate + H2O


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Bos taurus)


name: BRISC complex deubiquitinates NLRP3 (Xenopus tropicalis)


name: (3R)-hydroxytetracosanoyl-CoA + NADP(+) => 3-oxotetracosanoyl-CoA + NADPH + H(+)


name: N-hexadecanoylsphinga-(4E,8Z)-dienine + CoA + H(+) => sphinga-(4E,8Z)-dienine + hexadecanoyl-CoA


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 9-hydroperoxy-(5Z,7E,11Z,14Z)-eicosatetraenoate


name: (3R)-5-guanidino-3-methyl-2-oxopentanoate + L-aspartate => (3R)-3-methyl-L-arginine + oxaloacetate


name: all-trans-(3S,3'S)-astaxanthin + 2 A + 3 H2O => all-trans-adonixanthin + 2 AH2 + 2 O2


name: SUMOylation of PCNA with SUMO1 (Gallus gallus)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Danio rerio)


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Canis familiaris)


name: CYP2W1 oxidises INDOL (Caenorhabditis elegans)


name: OCT1 transports organic cations into hepatic cells (Caenorhabditis elegans)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Danio rerio)


name: cAMP binds PKA tetramer (Canis familiaris)


name: RasGRP interacts with DAG and Ca2+ (Homo sapiens)


name: urate(in) + n chloride(out) => urate(out) + n chloride(in)


name: SULT1A1 dimer sulfonates PARA to PARA-SO4 (Xenopus tropicalis)


name: 2-oxosuberate + CO2 + NADH => (2R,3S)-iso(homo)3citrate + NAD(+)


name: SOAT1,2 transfer acyl group to CHOL forming CHEST (Homo sapiens)


name: catechol + CO2 + NAD(+) + H2O => salicylate + NADH + O2 + 2 H(+)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: DLGAP5 gene transcription is stimulated by NOTCH3 (Homo sapiens)


name: juvenile hormone III + H2O = juvenile hormone III carboxylate + methanol + H(+)


name: TCN1 binds correnoids in the circulation (Homo sapiens)


name: positive regulation of prolactin signaling pathway


name: MLCL is acylated to CL by HADH (IM) (Drosophila melanogaster)


name: CHST10 transfers SO4(2-) from PAPS to GlcA-LacN on NCAM1 (Sus scrofa)


name: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine <=> 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + S-adenosyl-L-homocysteine + H(+)


name: SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Rattus norvegicus)


name: 3beta-hydroxy-5alpha-androstan-17-one + NADP(+) <=> 5alpha-androstan-3,17-dione + NADPH + H(+)


name: 3,7,11,15-tetramethylhexadecanoate + ATP + CoA <=> phytanoyl-CoA + AMP + diphosphate


name: CTLH E3 ligase ubiquitinates LDHA (Bos taurus)


name: 20beta-dihydrocortisone + NADP(+) => cortisone + NADPH + H(+)


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Rattus norvegicus)


name: 5-methylcytidine(48) in tRNA + S-adenosyl-L-homocysteine + H(+) => cytidine(48) in tRNA + S-adenosyl-L-methionine


name: 3-oxo-5beta-cholan-24-oate + NADH + H(+) = isolithocholate + NAD(+)


name: 7beta-hydroxy-3,12-dioxo-5beta-cholan-24-oate + NADP(+) <=> dehydrocholate + NADPH + H(+)


name: trans-Golgi Network Derived Vesicle Uncoating (Rattus norvegicus)


name: MTA is cleaved and phosphorylated (Homo sapiens)


name: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Rattus norvegicus)


name: 11cRAL binds to opsin to form 11c-retinyl:RHO (Mus musculus)


name: 5-dehydroepisterol + NADPH + O2 + H(+) => ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP(+) + 2 H2O


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP + H(+) => a 1,2-diacyl-sn-glycerol + UDP-alpha-D-galactose


name: PTK6 phosphorylates ARHGAP35 (Xenopus tropicalis)


name: MON1:CCZ1 exchanges GTP for GDP on RAB7 (Saccharomyces cerevisiae)


name: N-terminal L-leucyl-[protein] + acetyl-CoA <=> N-terminal N(alpha)-acetyl-L-leucyl-[protein] + CoA + H(+)


name: N-terminal N(alpha)-acetyl-L-cysteinyl-L-aspartyl-[protein] + H2O = N-terminal L-aspartyl-[protein] + N-acetyl-L-cysteine


name: (3R)-hydroxyeicosanoyl-CoA + NAD(+) <=> 3-oxoeicosanoyl-CoA + NADH + H(+)


name: S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] => glyoxal + L-cysteinyl-[protein]


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + AMP + diphosphate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ATP + CoA


name: AURKA phosphorylates PHLDA1 (Bos taurus)


name: methylenediurea + 2 H2O + 2 H(+) <=> N-(hydroxymethyl)urea + 2 NH4(+) + CO2


name: phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Rattus norvegicus)


name: salicylate + ATP + CoA => 2-hydroxybenzoyl-CoA + AMP + diphosphate


name: SUMOylation of TOP1 with SUMO1 (Danio rerio)


name: MAPK-dependent phosphorylation of KARS (Sus scrofa)


name: ethanolamine + O2 + H2O => glycolaldehyde + H2O2 + NH4(+)


name: (9Z)-octadecenoyl-CoA + H2O => (9Z)-octadecenoate + CoA + H(+)


name: 3-chlorocatechol + O2 <=> (2E,4Z)-2-chloromuconate + 2 H(+)


name: a neolactoside IV(4)-beta-GalNAc-IV(3)-alpha-NeuGc-nLc4Cer + UDP + H(+) => a neolactoside IV(3)-alpha-NeuGc-nLc4Cer + UDP-N-acetyl-alpha-D-galactosamine


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA


name: AKT-phosphorylated FOXO1,FOXO3,FOXO4 translocate to the cytosol (Homo sapiens)


name: Beta-galactosidases hydrolyze GM2A:GA1 to GM2A:GA2 (Mus musculus)


name: 3'-dehydromaltose + H2O = 3-dehydro-D-glucose + D-glucose


name: adenosine 5'-phosphoramidate + sulfate + 2 H(+) => adenosine 5'-phosphosulfate + NH4(+)


name: 3-aminobutan-2-ol + NADP(+) + H2O => acetoin + NH4(+) + NADPH + H(+)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Gallus gallus)


name: positive regulation of 5,10-methylenetetrahydrofolate reductase (FADH(2)) activity


name: gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + phosphate + H(+) => gamma-L-glutamyl-L-cysteine + beta-alanine + ATP


name: MT-MMPs are sorted to the plasma membrane (Rattus norvegicus)


name: (S)-indan-1-ol + NAD(+) <=> indan-1-one + NADH + H(+)


name: (6aS,11aS)-3,6a,9-trihydroxypterocarpan + dimethylallyl diphosphate <=> (6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + diphosphate


name: LIPC dimer hydrolyses TAG to DAG and FA (Xenopus tropicalis)


name: N-dodecanoyl-(4R)-hydroxysphinganine + H2O = (4R)-hydroxysphinganine + dodecanoate


name: passive transmembrane transporter activity


name: type III intermediate filament associated protein


name: stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential


name: (2E,11Z)-eicosadienoyl-CoA + NADPH + H(+) = (11Z)-eicosenoyl-CoA + NADP(+)


name: glycine + L-glutamate => glycyl-L-glutamate + H2O


name: [(1->2)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->2)-beta-D-glucosyl](n+1) + UDP + H(+)


name: ProGIP translocates from the ER Lumen to secretory granules (Gallus gallus)


name: a ganglioside GM1b (d18:1(4E)) + CMP + H(+) => a ganglioside GA1 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: glycine betaine + S-adenosyl-L-homocysteine + H(+) => N,N-dimethylglycine + S-adenosyl-L-methionine


name: a quinone + sulfite + H2O <=> a quinol + sulfate


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Xenopus tropicalis)


name: NEU1 hydrolyses Neu5Ac from glycoconjugates (Canis familiaris)


name: HDAC1:2-containing complex deacetylate histones (Drosophila melanogaster)


name: oxaloacetate(in) + sulfate(out) => oxaloacetate(out) + sulfate(in)


name: 1D-myo-inositol 1,4,5-trisphosphate + phosphate => 1D-myo-inositol 1,4,5,6-tetrakisphosphate + H2O


name: 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADH + H(+) => (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+)


name: TYW1:FMN:4Fe-4S  transforms 1-methylguanosine yielding yW-187 (4-demethylwyosine) at nucleotide 37 of tRNA(Phe) (Homo sapiens)


name: Calmodulin dissociates KRAS4B from the plasma membrane (Sus scrofa)


name: CR1 binds C3bBb/C4bC2a (Canis familiaris)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Danio rerio)


name: RAC1 translocates to the endoplasmic reticulum membrane (Mus musculus)


name: dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + reduced [flavodoxin] <=> dTDP-4-dehydro-2,3,6-trideoxy-alpha-D-hexopyranose + oxidized [flavodoxin] + H2O + H(+)


name: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate


name: stimulation of tissue kallikrein-kinin cascade


name: bHEXA,bHEXB hydrolyze GM2A:GA2 to GM2A:LacCer (Homo sapiens)


name: (9Z,12Z)-octadecadienoyl-CoA + H2O => S-(9Z,12Z-octadecadienoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: 5-hydroxy-L-tryptophan + (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + O2


name: PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) (Sus scrofa)


name: (-)-bursehernin + reduced [NADPH--hemoprotein reductase] + O2 = (-)-5'-demethylyatein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (E)-prop-1-en-1-SO-peroxol = (Z)-propanethial S-oxide


name: (2R,3R)-dihydrokaempferol + reduced [NADPH--hemoprotein reductase] + O2 = (2R,3R)-dihydroquercetin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a 2'-deoxyribonucleoside + a ribonucleoside 5'-phosphate = a ribonucleoside + a 2'-deoxyribonucleoside 5'-phosphate


name: Displacement of OGG1 glycosylase by APEX1 at the AP site (Bos taurus)


name: Activated FGFR4 phosphorylates PPTN11 (Gallus gallus)


name: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + acetyl-CoA = UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altrose + CoA + H(+)


name: Receptor CXC1 binds to the ligands lymphotactin and cytokine SCM-1 beta (Rattus norvegicus)


name: positive regulation of 5'-exonuclease activity


name: alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ <=> alpha-methylacetoacetyl-CoA + NADH + H+ (Canis familiaris)


name: 2-oxopent-4-enoate + salicylate => 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O


name: SeMet is converted to AdoSeMet by MAT (Rattus norvegicus)


name: glutamine + H2O => glutamate + NH4+ (GLS) (Homo sapiens)


name: carbon-oxygen lyase activity, acting on phosphates


name: (2S)-naringenin 4',7-dimethyl ether + reduced [NADPH--hemoprotein reductase] + O2 => (2S)-carthamidin-4',7-dimethyl ether + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Interaction of Csk with PAG (Homo sapiens)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+) => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 => 8,9-epoxy-(5Z,11Z,14Z,17Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: G alpha (z) inhibits adenylate cyclase (Bos taurus)


name: methylphosphonate + ATP => alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine


name: MAPK3-3 or MAPK1 phosphorylate GORASP2 (Sus scrofa)


name: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + NADH + H(+)


name: PCMT1 transfers CH3 from AdoMet to isoAsp to form MetAsp (Drosophila melanogaster)


name: IDS hydrolyses dermatan sulfate (Chebi:63517 chain) (Drosophila melanogaster)


name: SLC7A10-mediated uptake of small neutral amino acids (Xenopus tropicalis)


name: CMP-N-acetyl-beta-neuraminate(in) + CMP(out) <=> CMP-N-acetyl-beta-neuraminate(out) + CMP(in)


name: Collagen type IV sulfilimine cross-linking by peroxidasin (Homo sapiens)


name: PPM1K dephosphorylates p-BCKDH (Canis familiaris)


name: Truncated Alpha-1-Microglobulin binds heme (Xenopus tropicalis)


name: Digestion of cholesterol esters by extracellular CEL (bile salt-dependent lipase) (Gallus gallus)


name: ABCA5 transports CHOL from lysosomal lumen to cytosol (Bos taurus)


name: 2-aminoprop-2-enoate + sulfite + H(+) => L-cysteate


name: METAP1/2 demethylates GNAT1 (Xenopus tropicalis)


name: SUMOylation of NFKBIA with SUMO1 (Gallus gallus)


name: CYCS:APAF1 binds procaspase-9 (Mus musculus)


name: ubiquitin ligase complex scaffold activity


name: (17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + CO2 + CoA


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Rattus norvegicus)


name: PDCD1 binds PDCD1 inhibitors (Bos taurus)


name: Tankyrase ADP-ribosylates AXIN (Bos taurus)


name: Constitutive phosphorylation of FLT3 mutants (Homo sapiens)


name: RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Homo sapiens)


name: STARD7 transports Q10 to plasma membrane (Rattus norvegicus)


name: SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Danio rerio)


name: MGST trimers transfer GS from GSH to AFXBO and AFNBO (Mus musculus)


name: inhibition of protein O-linked glycosylation


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Bos taurus)


name: p-KIT mutants:GRB2:SOS catalyzes nucleotide exchange on RAS (Homo sapiens)


name: an N-acyl-aromatic L-alpha-amino acid + H2O <=> an aromatic L-alpha-amino acid + a carboxylate


name: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2


name: RELN:VLDLR:DAB1 binds SH3KBP1 (Homo sapiens)


name: Formation of the 43S pre-initiation complex (Caenorhabditis elegans)


name: (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMNH2 + O2 => N-acetyl-S-hydroxy-L-cysteine + benzaldehyde + FMN + H2O + H(+)


name: NR3C2 binds fludrocortisone (Sus scrofa)


name: Duplex siRNA is loaded into Argonaute (Canis familiaris)


name: TRIM33 monoubiquitinates SMAD4 (Bos taurus)


name: Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Sus scrofa)


name: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + H(+)


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Canis familiaris)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Gallus gallus)


name: pyridoxal + phosphate => pyridoxal 5'-phosphate + H2O


name: 3'-dephospho-CoA + ATP <=> ADP + CoA + H(+)


name: geranylgeranyl diphosphate + L-cysteinyl-[protein] <=> S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate


name: candesartan + UDP-alpha-D-glucuronate = candesartan O-beta-D-glucuronoside + UDP


name: Fibrillin C-terminal processing (Homo sapiens)


name: oxidoreductase activity, acting on CH or CH2 groups


name: protoheme IX farnesyltransferase activity


name: PMEPA1 sequesters unphosphorylated SMAD2/3 (Bos taurus)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Danio rerio)


name: L-arginyl-[methyl-coenzyme M reductase] + AH2 + 2 S-adenosyl-L-methionine => (5S)-C-methyl-L-arginyl-[methyl-coenzyme M reductase] + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)


name: RHAG transports CO2 from extracellular region to cytosol (Bos taurus)


name: PDPK1 phosphorylates SGK1 (Mus musculus)


name: L-cysteine(in) + Na(+)(in) => L-cysteine(out) + Na(+)(out)


name: Autophosphorylation of PTK2 at Y397 (Rattus norvegicus)


name: 4-O-{[(2R)-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP-alpha-D-glucose => 4-O-{[(2R)-2-alpha-D-glucosyl-1-glycerylphospho](n)-(2R)-1-glycerylphospho}-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl undecaprenyl diphosphate + n UDP + n H(+)


name: Translocation of DFF to the nucleus (Xenopus tropicalis)


name: beta-NGF dimer binds to TrkA receptor (Bos taurus)


name: CDK1 phosphorylates VCPIP1 (Gallus gallus)


name: 2 5'-dehydroinosine + 2 H2O => 2 inosine + O2


name: ADAMTS13 variant does not cleave VWF multimer (Homo sapiens)


name: 5alpha-cholesta-7,24-dien-3beta-ol + NADPH + O2 + H(+) <=> 7-dehydrodesmosterol + NADP(+) + 2 H2O


name: Activated FGFR2 phosphorylates SHC1 (Canis familiaris)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Dictyostelium discoideum)


name: L-glutamyl-tRNA(Gln) + ATP => 5-phosphooxy-L-glutamyl-tRNA(Gln) + ADP


name: AKRs reduce RBP2:atRAL to RBP2:atROL (Mus musculus)


name: cis-aconitate(in) + citrate(out) => cis-aconitate(out) + citrate(in)


name: GAR + 10-Formyl-THF => FGAR + THF (Drosophila melanogaster)


name: ent-kaur-16-ene + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) => ent-kaur-16-en-19-oate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O


name: 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O => 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + N-hexadecanoylethanolamine + H(+)


name: dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + acetyl-CoA <=> dTDP-4-acetamido-4,6-dideoxy-alpha-D-glucose + CoA + H(+)


name: intramembrane cleavage of ERAD substrate


name: HTR1A binds HTR1A agonists (Rattus norvegicus)


name: Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2 (Danio rerio)


name: a CMP-N-acyl-beta-neuraminate + H2O = an N-acylneuraminate + CMP + H(+)


name: FADH2-C4alpha-hydroperoxide + rifampicin + NADH <=> rifampicin hemiaminal + FADH2 + NAD(+) + H2O + H(+)


name: thiosulfate(out) + 3 Na(+)(out) <=> thiosulfate(in) + 3 Na(+)(in)


name: RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter (Homo sapiens)


name: L-valine(in) + ADP + phosphate + H(+) => L-valine(out) + ATP + H2O


name: G-proteins dissociate from plasma-membrane estrogen receptors (Bos taurus)


name: LONP1 degrades mitochondrial matrix proteins (Saccharomyces cerevisiae)


name: a 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA


name: ACSF2 ligates CoA-SH to MCFA (Mus musculus)


name: Arachidonate is epoxidated to 8,9-EET by CYP(5) (Danio rerio)


name: GDP-alpha-D-mannose + H2O => alpha-D-mannose 1-phosphate + GMP + 2 H(+)


name: 3,3',5-triiodo-L-thyronine + 3'-phosphoadenylyl sulfate => 3,3',5-triiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Homo sapiens)


name: NUDT15 hydrolyses 8-oxo-dGTP to 8-oxo-dGMP (Homo sapiens)


name: PLC beta-mediated PIP2 hydrolysis (Homo sapiens)


name: Movement of clathrin coated vesicles into early endosome (Bos taurus)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Rattus norvegicus)


name: hydroxylamine + 4 Fe(III)-[cytochrome c] + H2O <=> 4 Fe(II)-[cytochrome c] + nitrite + 5 H(+)


name: 6-deoxoteasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 <=> teasterone + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)


name: nascent chylomicron [endoplasmic reticulum lumen] => nascent chylomicron [extracellular] (Sus scrofa)


name: streptothricin F + H2O => streptothricin F acid


name: propanoate + ATP => propanoyl phosphate + ADP


name: (E)-hex-2-en-1-ol + NADP(+) => (E)-hex-2-enal + NADPH + H(+)


name: 10-deoxymethymycin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => neomethymycin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine (Xenopus tropicalis)


name: (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA (Dictyostelium discoideum)


name: STARD10 transports PC from ER membrane to lamellar body membrane (Homo sapiens)


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Saccharomyces cerevisiae)


name: (3R)-3-hydroxybutanoyl-CoA + [(3R)-hydroxybutanoate](n) = [(3R)-hydroxybutanoate](n+1) + CoA


name: Ubiquitination of phospho-p27/p21 (Xenopus tropicalis)


name: (20S)-ginsenoside Rg3 + D-glucose => (20S)-ginsenoside Rd + H2O


name: trichloro-p-hydroquinone reductive dehalogenase activity


name: DLD dimer dehydrogenates dihydrolipoyl (Drosophila melanogaster)


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Homo sapiens)


name: [amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate + 2-oxoglutarate => [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + L-glutamate


name: SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Rattus norvegicus)


name: 1,2-dioctanoyl-sn-glycero-3-phosphocholine + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phosphate + choline + H(+)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Mus musculus)


name: inosine(in) + H(+)(out) => inosine(out) + H(+)(in)


name: MKRN1 polyubiquitinates PTEN (Canis familiaris)


name: acrolein + putrescine => N-(4-aminobutyl)-3-aminopropanal


name: dihydro-ML-236C-[compactin nonaketide synthase] + H2O <=> holo-[compactin nonaketide synthase] + dihydro-ML-236C carboxylate + H(+)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Bos taurus)


name: Heparin cofactor 2 (SERPIND1) binds activated thrombin (factor IIa) (Mus musculus)


name: apo-[methylmalonyl-CoA:pyruvate carboxytransferase] + biotin + ATP = holo-[methylmalonyl-CoA:pyruvate carboxytransferase] + AMP + diphosphate + H(+)


name: Potassium voltage-gated channels close in reponse to PKA (Mus musculus)


name: SGK1 phosphorylates MDM2 (Gallus gallus)


name: d-4,5 unsaturated beta-glucuronyl hydrolase activity


name: 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+) => 2,3-dihydroxybenzoate + O2