name: Fc Epsilon Receptor I Signaling Pathway BioCarta


name: DMGDH:FAD oxidatively demethylates DMGLY to SARC (Homo sapiens)


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Caenorhabditis elegans)


name: corticotropin-releasing hormone receptor 2 binding


name: H2O2 oxidises ferrohemoglobin to MetHb (Sus scrofa)


name: long chain 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O <=> long chain acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+)


name: Formation of the 19S regulatory particle lid (Canis familiaris)


name: p38MAPK phosphorylates MSK1 (Dictyostelium discoideum)


name: Dissociation of Phospho-Nlp from the centrosome (Canis familiaris)


name: Relaxin receptor 2 binds relaxin 2 and INSL3 (Canis familiaris)


name: ALDH2 transforms GTN to NO (Saccharomyces cerevisiae)


name: (2S,3S)-3-methyl-L-aspartate = mesaconate + NH4(+)


name: 1-dodecanoyl-sn-glycerol 3-phosphate + choline + H(+) => 1-dodecanoyl-sn-glycero-3-phosphocholine + H2O


name: RPE65 isomero-hydrolyses atREs to 11cROL (Sus scrofa)


name: an N-(1,2-saturated acyl)sphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> an N-[(2'R)-hydroxyacyl]sphinganine + 2 Fe(III)-[cytochrome b5] + H2O


name: 7,4'-O-dimethylkaempferol + S-adenosyl-L-homocysteine + H(+) => kaempferide + S-adenosyl-L-methionine


name: ETFBKMT transfers 3xCH3 from 3xAdoMet to ETFB (Canis familiaris)


name: N-acetyl-demethyl-L-phosphinothricin + AH2 + 2 S-adenosyl-L-methionine => N-acetyl-L-phosphinothricin + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)


name: pyridoxine(in) + n H(+)(in) => pyridoxine(out) + n H(+)(out)


name: p-T816-PKN2 phosphorylates AKT1 on serine-308 (Mus musculus)


name: I(1,3,4,5,6)P5 transports from the nucleus to the cytosol (Homo sapiens)


name: Collagen type III degradation by MMP14 (Mus musculus)


name: NUDT1 hydrolyzes O6-methyl-dGTP to O6-methyl-dGMP (Sus scrofa)


name: ub-hydroxyPro-HIF-alpha:VHL:EloB,C:CUL2:RBX1 translocates from the nucleus to the cytosol (Caenorhabditis elegans)


name: Melanocortin receptors bind melanocortins (Gallus gallus)


name: (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one => (3S)-3-isopropenyl-6-oxoheptanoate + H(+)


name: (R)-4'-phospho-S-sulfopantetheine + H2O = (R)-S-sulfopantetheine + phosphate


name: IL10 positively regulates plasma membrane-associated inflammatory mediators (Homo sapiens)


name: phytol + a fatty acyl-CoA => a fatty acid phytyl ester + CoA


name: nicotinate(in) + 2 Na(+)(in) => nicotinate(out) + 2 Na(+)(out)


name: isopropylamine + L-glutamate + ATP = gamma-L-glutamyl-isopropylamide + ADP + phosphate + H(+)


name: (2Z,6Z)-farnesyl diphosphate => (1S,5S,6S)-alpha-bergamotene + diphosphate


name: a medium-chain 2,3-saturated fatty acyl-CoA + O2 <=> a medium-chain (2E)-enoyl-CoA + H2O2


name: regulation of non-canonical Wnt signaling pathway


name: XYLB phosphorylates D-xylulose (Mus musculus)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Canis familiaris)


name: a medium-chain (2E)-enoyl-CoA + H2O2 => a medium-chain 2,3-saturated fatty acyl-CoA + O2


name: TP53I3 oxidoreductase generates unstable semiquinones (Canis familiaris)


name: Interaction of particulate antigens with dendritic cell receptors (Homo sapiens)


name: ALDHs oxidise atRAL to atRA (Drosophila melanogaster)


name: (E)-4-hydroxyphenylacetaldehyde oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+) => L-tyrosine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2


name: ATXN3 family cleave Ub chains (Homo sapiens)


name: D-xylulose 1,5-bisphosphate + H2O = D-xylulose 5-phosphate + phosphate


name: UROD decarboxylates URO1 to COPRO1 (Dictyostelium discoideum)


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Schizosaccharomyces pombe)


name: a very-long-chain (3R)-3-hydroxyacyl-CoA = a very-long-chain (2E)-enoyl-CoA + H2O


name: STUB1 (CHIP) ubiquitinates SMAD3 (Bos taurus)


name: L-erythrulose 1-phosphate => dihydroxyacetone phosphate + formaldehyde


name: S,S-dimethyl-beta-propiothetin => acrylate + dimethyl sulfide + H(+)


name: cholate + FADH2 => deoxycholate + FAD + H2O + H(+)


name: p-Y407-YAP1 translocates from the cytosol to the nucleoplasm (Sus scrofa)


name: Caspase 3-mediated cleavage of PKC delta (Caenorhabditis elegans)


name: Proteasome degrades polyubiquitinated PTEN (Rattus norvegicus)


name: (-)-dehydrodiconiferyl acid + 2 a quinone + H2O => (-)-dehydrodiconiferyl acid carboxylate + 2 a quinol + H(+)


name: Phosphorylation of Cdc25C at Ser 216 by Chk1 (Caenorhabditis elegans)


name: IL34 dimer binds SDC1 (Xenopus tropicalis)


name: glycerol + a fatty acid + H(+) => a 2-acylglycerol + H2O


name: lipid A 4'-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol => lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+)


name: LPL hydrolyses TGs from mature CMs (Rattus norvegicus)


name: 1-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: blood-group substance beta-dependent galactosyltransferase activity


name: a 2-oxocarboxylate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA = an acyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)


name: negative regulation of guanyl-nucleotide exchange factor activity


name: regulation of ferricrocin biosynthetic process, peptide modification


name: Bombesin-like receptors bind bombesin homologues (Homo sapiens)


name: GRIN2A gene expression is stimulated by MECP2 (Homo sapiens)


name: ribostamycin + UDP-N-acetyl-alpha-D-glucosamine <=> 2'''-acetyl-6'''-hydroxyneomycin C + UDP + H(+)


name: RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Sus scrofa)


name: p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Bos taurus)


name: uridine(34) in tRNA + AH2 + O2 <=> 5-hydroxyuridine(34) in tRNA + A + H2O


name: PolyUb-Misfolded Proteins:HDAC6 bind dynein motor (Mus musculus)


name: positive regulation of polynucleotide adenylyltransferase activity


name: ZSWIM8 ubiquitinates ROBO3.1 (Homo sapiens)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus (Rattus norvegicus)


name: L-methionyl-L-phenylalanyl-L-methionine(out) + H(+)(out) = L-methionyl-L-phenylalanyl-L-methionine(in) + H(+)(in)


name: NADPH-dependent glycerin-3-phosphate dehydrogenase activity


name: P4HB:4-Hyp collagen propeptides dissociates (Canis familiaris)


name: NaS1 co-transports sulphate and a sodium ion (Homo sapiens)


name: arsenite + 2 Fe(III)-[cytochrome c] + H2O => arsenate + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Canis familiaris)


name: v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Mus musculus)


name: (2S)-naringenin + S-adenosyl-L-methionine => (2S)-naringenin 4'-methyl ether + S-adenosyl-L-homocysteine + H(+)


name: (3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O


name: MAF1 translocates to the nucleus (Caenorhabditis elegans)


name: DIMBOA beta-D-glucoside + S-adenosyl-L-homocysteine + H(+) => TRIBOA beta-D-glucoside + S-adenosyl-L-methionine


name: Dissociation of the P2Y purinoceptor 12:Gi complex (Sus scrofa)


name: (13Z)-docosenoyl-CoA + malonyl-CoA + H(+) = (15Z)-3-oxotetracosenoyl-CoA + CO2 + CoA


name: USP12, USP26 deubiquitinate AR (Mus musculus)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Schizosaccharomyces pombe)


name: Transport of VPU to Golgi apparatus (Homo sapiens)


name: Desaturation of alpha-linoleoyl-CoA to Stearidonoyl-CoA (Rattus norvegicus)


name: (2E,21Z,24Z,27Z,30Z)-hexatriacontapentaenoyl-CoA + NADPH + H(+) => (21Z,24Z,27Z,30Z)-hexatriacontatetraenoyl-CoA + NADP(+)


name: Interaction of integrin alphaVbeta3 with Tenascin (Canis familiaris)


name: NAGLU hydrolyses Heparan sulfate chain(4) (Dictyostelium discoideum)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)


name: SPI1 (PU.1), PML isoform 4, and EP300 bind the promoter of the CEBPE gene (Homo sapiens)


name: 2 cob(II)alamin + AH2 + 2 ATP <=> 2 adenosylcob(III)alamin + 2 triphosphate + A + 2 H(+)


name: glycerol-3-phosphate transmembrane transporter activity


name: HIPK2 phosphorylates MECP2 (Canis familiaris)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Bos taurus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Rattus norvegicus)


name: Activation of Talin (Xenopus tropicalis)


name: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O


name: (3S)-hydroxy-(9Z-octadecenoyl)-CoA + NAD(+) = 3-oxo-(9Z-octadecenoyl)-CoA + NADH + H(+)


name: Resumption of elongation after recovery from pausing (Rattus norvegicus)


name: sulfoacetyl-CoA + NADPH + H(+) => sulfoacetaldehyde + NADP(+) + CoA


name: cGMP binds CNG channel to form cGMP:CNG channel (Mus musculus)


name: beta-D-fructose + alpha-D-glucose => sucrose + H2O


name: chloroethene + AH2 => ethene + chloride + A + H(+)


name: sn-glycerol 3-phosphocholine + hexadecanoyl-CoA <=> hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: cyclohexanol + NAD(+) = cyclohexanone + NADH + H(+)


name: dAMP(in) + NAD(+)(out) = dAMP(out) + NAD(+)(in)


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Gallus gallus)


name: AJUBA binds centrosome-associated AURKA (Homo sapiens)


name: N-dodecanoylglycine + 2 L-ascorbate + O2 = N-dodecanoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O


name: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide


name: DBI, ACBD7 bind MCFA-CoA and LCFA-CoA (Rattus norvegicus)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Xenopus tropicalis)


name: Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Danio rerio)


name: Dissociation of  transcript with 5'-GMP from GT (Saccharomyces cerevisiae)


name: F protein binds NCL on host cell surface (Homo sapiens)


name: 4-phospho-D-erythronate + NAD(+) = dihydroxyacetone phosphate + CO2 + NADH


name: S-methyl-5-thio-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)ribulose 1-phosphate


name: [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + succinate + CO2 => [2-(trimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Canis familiaris)


name: (S)-methylmalonyl-CoA + H(+) <=> propanoyl-CoA + CO2


name: gypsogenate + UDP-alpha-D-glucose <=> gypsogenate 28-beta-D-glucoside + UDP


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Homo sapiens)


name: CDK4 in CCND1:CDK4:PRMT5:WDR77 phosphorylates WDR77 (Dictyostelium discoideum)


name: L-thyroxine(out) + an aromatic L-alpha-amino acid(in) => L-thyroxine(in) + an aromatic L-alpha-amino acid(out)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 2-[(5Z,8Z,11Z,14Z)-eicosatetraenoylamino]ethyl (9Z)-octadecenoate + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: syringate + (6S)-5,6,7,8-tetrahydrofolate <=> 3-O-methylgallate + (6S)-5-methyl-5,6,7,8-tetrahydrofolate


name: acylglycerone-phosphate reductase (NADP+) activity


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O <=> a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine


name: colnelenate + H2O => (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate


name: PI3K produces PIP3 and other phosphatidyl inositides (Homo sapiens)


name: UDP-alpha-D-galacturonate(in) + UMP(out) = UDP-alpha-D-galacturonate(out) + UMP(in)


name: L1-EGFR trans-heterodimerization (Xenopus tropicalis)


name: Guanine + H2O => Xanthine + NH4+ (Dictyostelium discoideum)


name: Inactive RAFs bind YWHAB (Xenopus tropicalis)


name: PRKCI phosphorylates ELF3 (Rattus norvegicus)


name: Phosphorylation of PIP2 to PIP3 by PI3K (Rattus norvegicus)


name: HM13 cleaves HMOX1 dimer (Gallus gallus)


name: Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA (Dictyostelium discoideum)


name: methylguanidine + H2O = urea + methylamine


name: 1-hexadecanoyl-sn-glycero-3-phosphate + NADP(+) = 1-hexadecanoylglycerone 3-phosphate + NADPH + H(+)


name: ADP-alpha-D-ribose 1'',2''-cyclic phosphate + H2O = ADP-alpha-D-ribose 1''-phosphate + H(+)


name: RHOQ GEFs activate RHOQ (Rattus norvegicus)


name: Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3  upon TLR7/8 or 9 activation (Bos taurus)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Rattus norvegicus)


name: triacetin + H2O => diacetylglycerol + acetate + H(+)


name: glycyl-L-glutamine(in) + H(+)(in) => glycyl-L-glutamine(out) + H(+)(out)


name: SLC25A10 mediates exchange of malate and phosphate (Sus scrofa)


name: 4alpha-formyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+) => 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: RPE dimers isomerise RU5P to XY5P (Danio rerio)


name: a beta-D-glucuronoside + alpha-D-glucose 1-phosphate => a 3-O-beta-D-glucosyl-beta-D-glucuronoside + phosphate


name: PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Canis familiaris)


name: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2


name: [Pyr1]apelin-13 + H2O => [Pyr1]apelin-12 + L-phenylalanine


name: methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + N-methyl-L-proline => Co(I)-[quaternary-amine-specific corrinoid protein] + L-proline betaine + H(+)


name: ATPase-coupled monoatomic cation transmembrane transporter activity


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Homo sapiens)


name: Activated human JNKs migrate to nucleoplasm (Mus musculus)


name: Activated FGFR4 binds PLCG1 (Mus musculus)


name: ALG13:ALG14 transfers GlcNAc from UDP-GlcNAc to GlcNAcDOLP (Mus musculus)


name: nitrilotriacetate + FMNH2 + O2 <=> aminodiacetate + FMN + glyoxylate + H2O


name: L-cystine(out) + ATP + H2O => L-cystine(in) + ADP + phosphate + H(+)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Sus scrofa)


name: p-S225-SPHK1 localizes to cytosol (Mus musculus)


name: CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Mus musculus)


name: Mg(2+)(out) + ATP + H2O => Mg(2+)(in) + ADP + phosphate + H(+)


name: (S)-styrene oxide + H2O = (S)-styrene glycol


name: (6Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate => 1-(9Z)-octadecenoyl-2-(6Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: SLC4A4 cotransports Na+ with 3HCO3- (Canis familiaris)


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Gallus gallus)


name: G-protein gated monoatomic cation channel activity


name: a ganglioside GD1b + acetyl-CoA = a ganglioside Ac-O-7-GD1b + CoA


name: SUMO-p-N protein dimer binds genomic RNA (Homo sapiens)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Drosophila melanogaster)


name: Syndecan-4:PI(4,5)P2 binds PKC alpha:DAG (Mus musculus)


name: Activation of RAC1 by VAV (Rattus norvegicus)


name: CYP3A4 monooxygenates ATV to 2-OH-ATV (Homo sapiens)


name: PEBP1 binds activated RAF1 (Gallus gallus)


name: D-serine(out) + H(+)(out) = D-serine(in) + H(+)(in)


name: ALOX5 oxidises 18(S)-HEPE to 5(S)-Hp-18(S)-HEPE (Dictyostelium discoideum)


name: a quinol + pyruvate => (R)-lactate + a quinone


name: Addition of N-acetyl-D-glucosamine to Dolichyl phosphate (Schizosaccharomyces pombe)


name: RhBG mediates ammonium influx into kidney collecting duct cells (Sus scrofa)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: hexadecanoyl-[ACP] + malonyl-[ACP] + H(+) => 3-oxooctadecanoyl-[ACP] + holo-[ACP] + CO2


name: a ganglioside GM3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine <=> a ganglioside GM2 (d18:1(4E)) + UDP + H(+)


name: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP(+) <=> a (3R)-2'-hydroxyisoflavanone + NADPH + H(+)


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Mus musculus)


name: fumarate + L-aspartate = iminosuccinate + succinate


name: D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)


name: TCR complex interacts with peptide antigen-presenting MHC Class I (Mus musculus)


name: gamma-secretase cleaves EPHB2 (Drosophila melanogaster)


name: ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Sus scrofa)


name: Fromation of the preholoimmunoproteasome (Bos taurus)


name: negative regulation of snoRNA metabolic process


name: 16alpha-hydroxy-beta-amyrin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2


name: Phosphorylated Cdc6 is exported from the nucleus (Plasmodium falciparum)


name: CYP4F8 19-hydroxylates PGH2 (Xenopus tropicalis)


name: inhibition of ribonucleic acid-dependent ribonucleic acid polymerase activity


name: 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + 2-oxoglutarate + O2 <=> 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + succinate + CO2


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + NADP(+) => (6R)-L-erythro-6,7-dihydrobiopterin + NADPH + H(+)


name: AKT-phosphorylated FOXO3 translocates to cytosol (Caenorhabditis elegans)


name: CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) (Mus musculus)


name: IL15 binds IL2RB:JAK1 and IL2RG:JAK3 (Sus scrofa)


name: HDAC8 deacetylates histones (Sus scrofa)


name: tetracosanoyl-CoA + hydrogencarbonate + ATP <=> 2-carboxytetracosanoyl-CoA + ADP + phosphate + H(+)


name: dGMP(in) + NAD(+)(out) => dGMP(out) + NAD(+)(in)


name: I(1,4,5)P3 is dephosphorylated to I(1,4)P2 by INPP5(4) in the cytosol (Canis familiaris)


name: SLC17A3-2 transports cytosolic urate to extracellular region (Bos taurus)


name: 1-docosanoylglycerol + H2O = docosanoate + glycerol + H(+)


name: BRAP binds RAS:GTP (Drosophila melanogaster)


name: PA is converted to CDP-DAG by CDS1 (Plasmodium falciparum)


name: RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex (Homo sapiens)


name: mycothiol + CoA + H(+) => 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA


name: a (2E,4E)-dienoyl-CoA + NADPH + H(+) => a 4,5-saturated-(3E)-enoyl-CoA + NADP(+)


name: bornane-2,6-dione + H2O = [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate + H(+)


name: BRD7 binds TP53 and EP300 (Drosophila melanogaster)


name: mRNA9 is translated to protein 9b (Homo sapiens)


name: (9Z,12Z)-octadecadienoate(out) + ATP(in) + CoA(in) + H(+)(out) = (9Z,12Z)-octadecadienoyl-CoA(in) + AMP(in) + diphosphate(in) + H(+)(in)


name: Dissociation of cytosolic HSF1:HSP90 complex (Saccharomyces cerevisiae)


name: 4-amino-L-phenylalanine + holo-[peptidyl-carrier protein] + ATP <=> 4-amino-L-phenylalanyl-[peptidyl-carrier protein] + AMP + diphosphate


name: D-mannose 6-phosphate + H2O => D-mannose + phosphate


name: L-alanine(in) + Na(+)(in) => L-alanine(out) + Na(+)(out)


name: Exocytosis of secretory granule lumen proteins (Caenorhabditis elegans)


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Canis familiaris)


name: CDP-D-glucose + diphosphate => alpha-D-glucose 1-phosphate + CTP + H(+)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Rattus norvegicus)


name: USP9X (FAM) deubiquitinates SMAD4 (Bos taurus)


name: PTK6 translocates to the nucleus (Sus scrofa)


name: dIMP + inosine <=> 2'-deoxyinosine + IMP


name: UBA1 adenylates ubiquitin in the nucleoplasm (Gallus gallus)


name: Activation of Ca impermeable AMPA receptors (Caenorhabditis elegans)


name: MAPK4,6 translocate to nucleus (Gallus gallus)


name: furfural + NAD(+) + H2O = 2-furoate + NADH + 2 H(+)


name: hancockiamide G + AMP + diphosphate => hancockiamide H + (E)-cinnamate + ATP


name: Phosphorylation of ZAP-70 by Lck (Sus scrofa)


name: 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: a primary linear alkyl sulfate ester + 2-oxoglutarate + O2 = an aldehyde + sulfate + succinate + CO2 + H(+)


name: Group 3 - Selective Cl- transport (Canis familiaris)


name: RNA demethylases demethylate N6-methyladenosine RNA (Mus musculus)


name: RAC2 GDIs block activation of RAC2 (Xenopus tropicalis)


name: (S)-carnitine + ATP + CoA => (S)-carnitinyl-CoA + ADP + phosphate


name: ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)


name: (3S)-citramalate(in) + sulfate(out) = (3S)-citramalate(out) + sulfate(in)


name: a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA


name: dodecanal + O2 + H2O = dodecanoate + H2O2 + H(+)


name: D-ribose 5-phosphate + 2'-deoxyadenosine 5'-triphosphate (dATP) => 5-Phospho-alpha-D-ribose 1-diphosphate (PRPP) + 2'-deoxyadenosine 5'-monophosphate (Schizosaccharomyces pombe)


name: glycyl-L-glutamine + H2O <=> L-glutamine + glycine


name: an aromatic aldehyde + AMP + diphosphate + NADP(+) => an aromatic carboxylate + ATP + NADPH + H(+)


name: FRK phosphorylates PTEN (Canis familiaris)


name: Transfer of GMP from the capping enzyme GT site to 5'-end of mRNA (Caenorhabditis elegans)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2 + H2O => 2-dehydro-D-glucose + glycine + H2O2


name: 2 sulochrin + O2 + 2 H(+) = 2 (2S)-bisdechlorogeodin + 2 H2O


name: ectocarpin A + H2O => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: endothelial differentiation G-protein coupled receptor ligand


name: prephenate + L-aspartate => L-arogenate + oxaloacetate


name: a medium-chain fatty acyl-[ACP] + AMP + H(+) => a medium-chain fatty acyl-AMP + holo-[ACP]


name: HIPK2 phosphorylates TP53 (Canis familiaris)


name: 2-methylpropanenitrile + reduced [NADPH--hemoprotein reductase] + O2 => 2-hydroxy-2-methylpropanenitrile + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA => (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + malonyl-CoA + H(+)


name: eicosanoyl-CoA + taurine <=> N-eicosanoyl-taurine + CoA + H(+)


name: Co-precorrin-5A + H2O = Co-precorrin-5B + acetaldehyde + H(+)


name: GALE:NAD+ dimer reversibly epimerises UDP-Gal to UDP-Glc (Caenorhabditis elegans)


name: Fibronectin degradation by CTSG (Mus musculus)


name: N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate => dimethylallyl diphosphate + AMP


name: IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Canis familiaris)


name: [DsrC protein]-disulfide + sulfite + H(+) => [DsrC protein]-S-sulfo-L-cysteine/L-cysteine


name: SOD3 catalyzes 2H+ + 2O2.- => O2 + H2O2 (extracellular) (Dictyostelium discoideum)


name: a globoside Gb3Cer + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside Gb4Cer + UDP + H(+)


name: D-maltose(out) + ATP + H2O => D-maltose(in) + ADP + phosphate + H(+)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Caenorhabditis elegans)


name: 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) <=> 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)


name: Caspase-mediated cleavage of Desmoplakin (Bos taurus)


name: POLK and POLZ cooperate in elongation of mispaired primer termini (Canis familiaris)


name: phosphinomethylisomalate => 2-(phosphinatomethylidene)butanedioate + H2O


name: eugenol + a carboxylate + NADP(+) = a coniferyl ester + NADPH


name: BRWD1 gene expression is repressed by STAT5 (Homo sapiens)


name: AFG3L2 binds mitochondrial inner membrane proteins (Schizosaccharomyces pombe)


name: an N-(2,3-dihydroxyhexacosanoyl)-(4R)-hydroxysphinganine + 2 Fe(III)-[cytochrome b5] + H2O = N-(2-hydroxyhexacosanyl)-(4R)-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: quercetin + S-adenosyl-L-methionine = isorhamnetin + S-adenosyl-L-homocysteine + H(+)


name: TBC1D7 binds the TSC1-TSC2 complex (Mus musculus)


name: RHOJ GEFs activate RHOJ (Rattus norvegicus)


name: KDM5A-D demethylate Me2K5-histone H3 (Saccharomyces cerevisiae)


name: G alpha (q) binds to Trio family RhoGEFs (Danio rerio)


name: L-aspartate 4-semialdehyde + L-glutamate => L-2,4-diaminobutanoate + 2-oxoglutarate


name: SESN1,2 binds L-leucine and dissociates from GATOR2 (Gallus gallus)


name: GTSE1 facilitates proteasome-mediated degradation of TP53 (Danio rerio)


name: (2E,6E)-farnesyl diphosphate + H2O <=> patchoulol + diphosphate


name: TRAF3 binds TICAM1:activated TLR4 complex (Rattus norvegicus)


name: 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + NH4(+) = D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + H2O + H(+)


name: 2,5-dihydroxybenzoate + H(+) <=> hydroquinone + CO2


name: PI3K associates with phosphorylated GAB2 (Rattus norvegicus)


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Danio rerio)


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Xenopus tropicalis)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Canis familiaris)


name: Phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 bind PI3K (Homo sapiens)


name: Addition of GlcNAc to Core 3 forms a Core 4 glycoprotein (Caenorhabditis elegans)


name: DSCAM/DSCAML1 homodimerization (Rattus norvegicus)


name: N-eicosanoylglycinate + H2O => eicosanoate + glycine


name: regulation of sphingolipid signaling pathway


name: Insertion of MHC II:Ii complex in to the plasma membrane (Bos taurus)


name: 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + S-adenosyl-L-methionine = 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + S-adenosyl-L-homocysteine + H(+)


name: a ganglioside GT1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b + CMP + H(+)


name: FAR2 reduces PalmCoA to HXOL (Canis familiaris)


name: Phosphorylation of L1 by ERK (Sus scrofa)


name: Addition of a second mannose to the N-glycan precursor by ALG2 (Mus musculus)


name: Recruitment of SYK to p-DAP12 (Gallus gallus)


name: FUT8 transfers fucosyl group from GDP-Fuc to GlcNAc of NGP (Danio rerio)


name: a carboxylic ester + H2O => an alcohol + a carboxylate + H(+)


name: CMP-N-acetyl-beta-neuraminate(out) + AMP(in) => CMP-N-acetyl-beta-neuraminate(in) + AMP(out)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Drosophila melanogaster)


name: Caspase-8 and FLIP(L) processing at TNFR signaling complex (Canis familiaris)


name: GMP + NADPH + 2 H(+) => IMP + NH4(+) + NADP(+)


name: (S)-scoulerine + reduced [NADPH--hemoprotein reductase] + O2 = (S)-cheilanthifoline + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Mus musculus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: D-arabinose 1-dehydrogenase (NAD+) activity


name: Receptors CCR3, 4 and 5 bind CCL5 ligand (Gallus gallus)


name: 7-oxoresolvin D2 + NADH + H(+) => resolvin D2 + NAD(+)


name: JAK2 transphosphorylates and is activated in response to Erythropoietin (Homo sapiens)


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Sus scrofa)


name: PARP1 ADP-ribosylates SMAD3 and SMAD4 (Drosophila melanogaster)


name: XPC binds RAD23 and CETN2 (Xenopus tropicalis)


name: Dephosphorylation of p130 (RBL2) by PP2A (Drosophila melanogaster)


name: L-pipecolate + malonyl-CoA + 3 NADPH + 5 H(+) = (1R,8aS)-octahydroindolizin-1-ol + CO2 + 3 NADP(+) + CoA + 2 H2O


name: a 1,2-diacyl-sn-glycero-3-phosphocholine + L-serine => a 1,2-diacyl-sn-glycero-3-phospho-L-serine + choline


name: alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Schizosaccharomyces pombe)


name: uracil + (deoxy)ribose 1-phosphate <=> (deoxy)uridine + orthophosphate [UPP] (Sus scrofa)


name: uridine-5'-carboxamide + CO2 + H2O => (5'S,6'R)-C-glycyluridine + O2


name: Inhibition of JAK kinase activity by SOCS1/3 (Homo sapiens)


name: a propanoate ester + H2O = an aliphatic alcohol + propanoate + H(+)


name: SLC6A3 binds DRIs (Plasmodium falciparum)


name: serotonin + octadecanoyl-CoA <=> N-octadecanoyl-serotonin + CoA + H(+)


name: ALDH3A2-2 oxidizes pristanal to pristanate (Homo sapiens)


name: Hemoglobin:Haptoglobin:CD163 is endocytosed (Rattus norvegicus)


name: 2,4,7,9-tetrahydroxy-6-methyl-8-(2-methylbut-3-en-2-yl)-1-oxo-1H-phenalen-3-ol + diphosphate => 2,3,4,7,9-pentahydroxy-6-methyl-1H-phenalen-1-one + dimethylallyl diphosphate


name: all-trans-phytofluene + A => all-trans-zeta-carotene + AH2


name: (1R,4R)-camphor + NADH + H(+) => (1R,2S,4R)-borneol + NAD(+)


name: [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-en-1-yl]acetate + ATP + CoA => [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + AMP + diphosphate


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Homo sapiens)


name: sulfate(out) + phosphate(in) + H(+)(in) = sulfate(in) + phosphate(out) + H(+)(out)


name: HSF1 acetylation at Lys80 (Rattus norvegicus)


name: carboxyspermidine + NADP(+) + H2O = L-aspartate 4-semialdehyde + putrescine + NADPH + H(+)


name: a 2-oxocarboxylate + H2O2 + NH4(+) => a D-alpha-amino acid + O2 + H2O


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Homo sapiens)


name: a (22S)-22-hydroxy C29-steroid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => a C29-steroid + reduced [NADPH--hemoprotein reductase] + O2


name: Kinesin-1 is a heterotetramer (Sus scrofa)


name: 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP <=> 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + phosphate + H(+)


name: methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP-beta-L-fucose <=> methyl 8-{[N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP + H(+)


name: NFKB1:RELA translocates from the cytosol to the nucleus (Gallus gallus)


name: HSBP1 binds HSF1 trimer (Drosophila melanogaster)


name: CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol (Sus scrofa)


name: C-3 sterol dehydrogenase (C-4 decarboxylase) activity


name: (20S)-protopanaxadiol + reduced [NADPH--hemoprotein reductase] + O2 => (20S)-protopanaxatriol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (2E,6E)-farnesyl diphosphate => alpha-humulene + diphosphate


name: RAC2 translocates to the ER membrane (Caenorhabditis elegans)


name: Elastin degradation by elastin-degrading extracellular proteinases (Homo sapiens)


name: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H2O


name: L-ornithine + NADH + O2 <=> N(5)-hydroxy-L-ornithine + NAD(+) + H2O


name: delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity


name: an omega-methyl-very-long-chain fatty acid + reduced [NADPH--hemoprotein reductase] + O2 => an omega-hydroxy-very-long-chain fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 1D-myo-inositol 2,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,5-triphosphate + phosphate


name: 3,3'-diiodo-L-thyronine + 3'-phosphoadenylyl sulfate = 3,3'-diiodo-L-thyronine sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Sus scrofa)


name: (2E,6E)-farnesyl diphosphate => (+)-aristolochene + diphosphate


name: FADH2-C4alpha-hydroperoxide + NAD(+) => FAD + NADH + O2 + 2 H(+)


name: Alpha-2A,alpha-2C Adrenergic Receptors activate Gi.Go heterotrimeric G proteins (Mus musculus)


name: Autophosphorylation of PAK (Rattus norvegicus)


name: p-S167-ESR1 activates expression of HTRA2 (OMI) (Homo sapiens)


name: 3-oxopropanoate + NAD(+) + CoA + H2O => hydrogencarbonate + acetyl-CoA + NADH + H(+)


name: insulin-like growth factor receptor ligand


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Danio rerio)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[15] (Danio rerio)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Danio rerio)


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Dictyostelium discoideum)


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Caenorhabditis elegans)


name: RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Sus scrofa)


name: (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA + NAD(+) => (S)-2-benzoylsuccinyl-CoA + NADH + H(+)


name: VAV2 is a GEF for Rho/Rac family kinases (Rattus norvegicus)


name: dodecanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> (2E)-dodecenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 2 a Fe(III)-siderophore + NADPH => 2 a Fe(II)-siderophore + NADP(+) + H(+)


name: SOAT1,2 transfer acyl group to CHOL forming CHEST (Gallus gallus)


name: (R)-glycerate + NAD(+) <=> 3-hydroxypyruvate + NADH + H(+)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) => (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin]


name: (2E,6E)-farnesyl diphosphate = (-)-delta-cadinene + diphosphate


name: RAN stimulates fusion of nuclear envelope (NE) membranes (Saccharomyces cerevisiae)


name: PC is exchanged with PI by PITPNB (Canis familiaris)


name: UDP(in) + ATP(out) => UDP(out) + ATP(in)


name: p52:RELB translocates from cytosol to nucleus (Drosophila melanogaster)


name: Polyubiquitination of substrate (Mus musculus)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Sus scrofa)


name: Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC (Sus scrofa)


name: stimulation of transforming growth factor-beta1 production


name: D-cellotriose + O2 = D-cellotriono-1,5-lactone + H2O2


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Sus scrofa)


name: FPGS-2 transforms THF to THFPG (Bos taurus)


name: Phosphorylation of ZAP-70 by Lck (Bos taurus)


name: regulation of phosphodiesterase I activity


name: 4-methyl-5-nitrocatechol + NADPH + O2 => 2-hydroxy-5-methylquinone + nitrite + NADP(+) + H2O + H(+)


name: IRAK4 binds to the activated TLR7 or 21 (Gallus gallus)


name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Xenopus tropicalis)


name: beta-citrylglutamate(in) + ATP + H2O => beta-citrylglutamate(out) + ADP + phosphate + H(+)


name: 4-aminobutanal + NADP(+) + H2O => 4-aminobutanoate + NADPH + 2 H(+)


name: intermembrane oxysterol transfer activity


name: Brevican degradation by MMP1, 2, 3, 7,8,10,13,19 (Xenopus tropicalis)


name: MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix (Drosophila melanogaster)


name: sn-glycero-3-phospho-1D-myo-inositol + a fatty acid + H(+) => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O


name: an alkanesulfonate + FMNH2 + O2 => an aldehyde + FMN + sulfite + H2O + 2 H(+)


name: Gonadotropin Releasing Hormone Receptor Agonists


name: MAT2B:MAT2A:K+:2Mg2+ transfers Ado from ATP to L-Met (Mus musculus)


name: YWHAE (14-3-3 epsilon) dimer binds phosphorylated WWTR1 (TAZ) (Gallus gallus)


name: SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Rattus norvegicus)


name: BRCA1 binds phosphorylated RBBP8 (Rattus norvegicus)


name: G protein-coupled olfactory receptor activity


name: DNA polymerase alpha:primase binds at the origin (Homo sapiens)


name: dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA (Drosophila melanogaster)


name: ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Xenopus tropicalis)


name: (2S)-carthamidin-4',7-dimethyl ether + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (2S)-naringenin 4',7-dimethyl ether + reduced [NADPH--hemoprotein reductase] + O2


name: adenylyl-molybdopterin + molybdate = Mo-molybdopterin + AMP + H(+)


name: GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Gallus gallus)


name: alpha-D-Gal-(1->6)-beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + H2O <=> beta-D-Man-(1->4)-beta-D-Man-(1->4)-D-Man + D-galactose


name: Latent TGF-beta-1 is cleaved by FURIN (Sus scrofa)


name: AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Rattus norvegicus)


name: Trans-homophilic interaction of PECAM-1 (Bos taurus)


name: THBS1 gene transcription is stimulated by the complex containing RUNX1, PRMT1 and GATA1 and inhibited by the complex of RUNX1, SIN3A and PRMT6 (Homo sapiens)


name: SUMOylation of TFAP2C with SUMO1 (Rattus norvegicus)


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(out) + ADP + phosphate + H(+) => (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(in) + ATP + H2O


name: CDC42 GAPs stimulate CDC42 GTPase activity (Saccharomyces cerevisiae)


name: a 2,3-saturated acyl-CoA + NADP(+) <=> a 2,3-dehydroacyl-CoA + NADPH + H(+)


name: Dimerization of LIMK1 by Hsp90 (Gallus gallus)


name: all-trans-beta-carotene + O2 <=> beta-ionone + all-trans-10'-apo-beta-carotenal


name: Squalene is oxidized to its epoxide (Rattus norvegicus)


name: sucrose 6(F)-phosphate + UDP + H(+) => beta-D-fructose 6-phosphate + UDP-alpha-D-glucose


name: N(3)-1,2-dicarboxyethyl-diaminobutanoate => (2S,3R)-diaminobutanoate + fumarate


name: tRNA(Ala) + glycine + H(+) => glycyl-tRNA(Ala) + H2O


name: Activated FGFR3:p-FRS bind to PPTN11 (Homo sapiens)


name: p-PRKRA dimer binds PKR (Drosophila melanogaster)


name: MANBA hydrolyses GlcNAc:Man (Drosophila melanogaster)


name: PTPN1 and PTPN2 dephosphorylate MET (Xenopus tropicalis)


name: An anchoring protein, Endofin, recruits R-Smad1/5/8 (Homo sapiens)


name: ADH1A,1C,4 oxidise atROL to atRAL in vitro (Bos taurus)


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Canis familiaris)


name: apoTF:TFRC dimer translocates from endosome membrane to plasma membrane (Homo sapiens)


name: Phosphorylation of CARMA1 by PKC-theta (Sus scrofa)


name: inhibition of metalloendopeptidase activity involved in APP catabolic process


name: DLD dimer dehydrogenates dihydrolipoyl (Sus scrofa)


name: cholate + L-serine <=> L-serocholate + H2O


name: propanoate + acetyl-CoA = propanoyl-CoA + acetate


name: [protein]-dithiol + [thioredoxin]-disulfide = [protein]-disulfide + [thioredoxin]-dithiol


name: 3-dehydro-L-erythronate + ATP = 3-dehydro-4-O-phospho-L-erythronate + ADP + H(+)


name: RAB8A,10,13,14 exchange GDP for GTP (Homo sapiens)


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Plasmodium falciparum)


name: 7,8-dihydroneopterin <=> 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde


name: 3-oxododecanoate + CoA + H(+) => 3-oxododecanoyl-CoA + H2O


name: activation of 3-OH androgenic UDPGT activity


name: PLK1 hyperphosphorylates Condensin II complex (Rattus norvegicus)


name: 4xPALM-C-p-2S-ABCA1 tetramer binds APOA1 (Mus musculus)


name: ALDH2 transforms GTN to NO (Rattus norvegicus)


name: (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + O2 => (3R,6R)-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: Uncoupled eNOS favours the formation of superoxide (Rattus norvegicus)


name: Phosphorylation of MEK7 by MEKK1 (Rattus norvegicus)


name: cytidine(4447) in 28S rRNA + S-adenosyl-L-methionine => 5-methylcytidine(4447) in 28S rRNA + S-adenosyl-L-homocysteine + H(+)


name: 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA => 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoyl-CoA


name: CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Rattus norvegicus)


name: 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: Monoubiquitination of FANCD2:FANCI (Homo sapiens)


name: ALOX5 oxidises DPAn-3 to 7-HDPAn-3 (Bos taurus)


name: Initial binding of AP-2 and clathrin to PI(4,5)P2 (Mus musculus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the early endosome membrane (Dictyostelium discoideum)


name: an N-acyl-(4R)-4-hydroxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a (4R,8E)-4-hydroxysphingenine ceramide + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: CES1,CES2 hydrolyze ASA- to ST (Mus musculus)


name: RHOD binds effectors at the Golgi membrane (Sus scrofa)


name: regulation of deoxyribonucleate topoisomerase


name: AKR1B15 reduces EST17b to E1 (Drosophila melanogaster)


name: F8 variant does not bind von Willebrand factor (Homo sapiens)


name: N-hydroxy-L-aspartate + NADPH + O2 + H(+) = N,N-dihydroxy-L-aspartate + NADP(+) + H2O


name: CaMKII binds activated calmodulin (Homo sapiens)


name: GALT transfers UMP from UDP-Glc to Gal1P to form UDP-Gal (Drosophila melanogaster)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O => 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoate + H(+)


name: Casein kinase II phosphorylates PTEN (Saccharomyces cerevisiae)


name: a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+) => a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O


name: (Z)-3-aminoacrylate + H2O + H(+) = 3-oxopropanoate + NH4(+)


name: N-octadecanoylsphing-4-enine + H2O <=> sphing-4-enine + octadecanoate


name: Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4  (Rattus norvegicus)


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n-1) + 4-deoxy-6-O-methyl-L-threo-hex-4-enopyranuronate => [(1->4)-alpha-D-galacturonosyl methyl ester](n)


name: (2E,6E)-farnesyl diphosphate => (+)-(E)-beta-caryophyllene + diphosphate


name: tetradecanoate + H2O2 <=> (2S)-hydroxytetradecanoate + H2O


name: 6-hydroxy-L-homoarginine => guanidine + (S)-2-amino-6-oxohexanoate


name: N(omega),N(omega)-dimethyl-L-arginine(in) + L-lysine(out) <=> N(omega),N(omega)-dimethyl-L-arginine(out) + L-lysine(in)


name: all-trans-8'-apo-beta-carotenal + O2 = (2E,4E,6E)-2,6-dimethylocta-2,4,6-trienedial + all-trans-retinal


name: ent-kaur-16-en-19-oate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = ent-7alpha-hydroxykaur-16-en-19-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor


name: taurohyocholate(out) + 2 Na(+)(out) => taurohyocholate(in) + 2 Na(+)(in)


name: GLI3R binds the GLI1 promoter (Homo sapiens)


name: SHP2 dephosphorylates Tyr 992 on EGFR (Gallus gallus)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA <=> 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + CoA


name: RHOF GAPs stimulate RHOF GTPase activity (Rattus norvegicus)


name: HYAL1 hydrolyses Chondroitin chains (Danio rerio)


name: activation of butyryl-CoA catabolic process to butanol


name: RBP4:atROL binds TTR (Rattus norvegicus)


name: Interleukin-12 binds Interleukin-12 receptor (Bos taurus)


name: a very-long-chain (3R)-3-hydroxyacyl-CoA + NAD(+) => a very-long-chain 3-oxoacyl-CoA + NADH + H(+)


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Gallus gallus)


name: L-2,4-diaminobutanoate + acetyl-CoA = (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: PARG dePARylates PARP1,PARP2 (Gallus gallus)


name: DHNTP is dephosphorylated by PTPS to PTHP (Dictyostelium discoideum)


name: 11-O-acetylcyathin A3 + AH2 => 11-O-acetylcyathatriol + A


name: prostaglandin D2 + NADPH + H(+) => 11beta-prostaglandin F2 + NADP(+)


name: Translocation of YAP1 to the nucleus (Danio rerio)


name: POU5F1 (OCT4), NANOG bind the CDX2 promoter (Homo sapiens)


name: (-)-secoisolariciresinol + NADP(+) <=> (+)-lariciresinol + NADPH + H(+)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Drosophila melanogaster)


name: 3-oxododecanoyl-CoA + NADH + H(+) => (3R)-3-hydroxydodecanoyl-CoA + NAD(+)


name: guanosine(out) + H(+)(out) => guanosine(in) + H(+)(in)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Schizosaccharomyces pombe)


name: AcM-UBE2M transfers NEDD8 to CUL9:RBX1 (Homo sapiens)


name: PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body (Danio rerio)


name: (S)-N-methylcoclaurine + reduced [NADPH--hemoprotein reductase] + O2 <=> (S)-3'-hydroxy-N-methylcoclaurine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Homo sapiens)


name: 7-carboxy-7-deazaguanine + NH4(+) + ATP => 7-cyano-7-deazaguanine + ADP + phosphate + H2O + H(+)


name: demethyldeoxyspectinabilin + S-adenosyl-L-methionine <=> deoxyspectinabilin + S-adenosyl-L-homocysteine


name: CYP4F22 20-hydroxylates TrXA3 (Canis familiaris)


name: NAMPT transfers PRIB to NAM to form NAMN (Mus musculus)


name: FAD attaches to SDHA (Xenopus tropicalis)


name: a (2R)-2-hydroperoxy fatty acid + H(+) <=> a fatty aldehyde + CO2 + H2O


name: Conversion of glyoxylate to oxalate (Canis familiaris)


name: TPX2 binds AURKA at centrosomes (Gallus gallus)


name: D-serine(in) + L-glutamine(out) + Na(+)(out) <=> D-serine(out) + L-glutamine(in) + Na(+)(in)


name: 9alpha-copalyl diphosphate => 9beta-pimara-7,15-diene + diphosphate


name: 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O => 1D-myo-inositol hexakisphosphate + phosphate + H(+)


name: a 5'-end phospho-guanosine in mRNA + N(7)-methyl-GDP + 2 H(+) => a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O


name: dihydroserpentine + A <=> serpentine + AH2


name: AHCY:NAD+ tetramer hydrolyses AdoHcy (Sus scrofa)


name: E2F1 binds the PCNA gene promoter (Homo sapiens)


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Bos taurus)


name: HOXA3 chromatin is activated (Homo sapiens)


name: ANKLE2 binds VRK1,(VRK2) (Canis familiaris)


name: Coagulation factor VII activity | Platelet poor plasma | Coagulation


name: N(6)-(D-fructosyl)-L-lysine + ATP = N(6)-(6-phospho-D-fructosyl)-L-lysine + ADP + H(+)


name: gibberellin A4 + succinate + CO2 => gibberellin A9 + 2-oxoglutarate + O2


name: ALDH1L1 dehydrogenates 10-formyl-THFPG to THFPG (Bos taurus)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Sus scrofa)


name: 4-hydroxy-L-lysyl-[protein] + succinate + CO2 => L-lysyl-[protein] + 2-oxoglutarate + O2


name: 3,3',5-triiodo-L-thyronine(out) + L-glutamate(in) = 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out)


name: AP-1 transcription factor, JRA:KAY, is phosphorylated by phosphorylated BSK kinase (Drosophila melanogaster)


name: L-methionine + 2-oxoglutarate <=> 4-methylsulfanyl-2-oxobutanoate + L-glutamate


name: inhibition of microtubule severing activity


name: WIPIs bind PI3P (Schizosaccharomyces pombe)


name: TGFBR3_mem cleavage by MMPs (Danio rerio)


name: taurine + (5Z,8Z,11Z,14Z)-eicosatetraenoate => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-taurine + H2O


name: The acetyl group from acetyl-CoA is transferred to the NAT2 (Bos taurus)


name: FBP tetramers hydrolyze F1,6PP to Fru(6)P (Saccharomyces cerevisiae)


name: Recruitment of CBL to KIT (Drosophila melanogaster)


name: phosphonate(out) + ATP + H2O => phosphonate(in) + ADP + phosphate + H(+)


name: oxidized coenzyme F420-0 + GTP + L-glutamate => oxidized coenzyme F420-1 + GDP + phosphate + H(+)


name: Collagen type VIII degradation by MMP1 (Sus scrofa)


name: phospholipase C-activating G protein-coupled receptor signaling pathway


name: Translation of ROBO3.2 mRNA initiates NMD (Homo sapiens)


name: PCSK1 hydrolyzes acyl Proghrelin to acyl Ghrelin (Danio rerio)


name: LIG3-mediated DNA ligation via the single-nucleotide replacement pathway (Homo sapiens)


name: GRB2:SOS interacts with p-KIT (Canis familiaris)


name: N-eicosanoylglycinate + CoA + H(+) => eicosanoyl-CoA + glycine


name: N-acyl-15-methylhexadecasphinganine + H2O = 15-methylhexadecasphinganine + a carboxylate


name: HIRA and NPM2 assemble H3.3-containing nucleosomes on paternal DNA (Homo sapiens)


name: K(+)(out) + chloride(out) => K(+)(in) + chloride(in)


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Plasmodium falciparum)


name: 1-butanoyl-2-(9Z-octadecenoyl)-glycerol + CoA => 2-(9Z-octadecenoyl)-glycerol + butanoyl-CoA


name: All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Homo sapiens)


name: G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Canis familiaris)


name: (3R)-hydroxyhexanoyl-[ACP] = (2E)-hexenoyl-[ACP] + H2O


name: MUS81 binds EME1, EME2 (Xenopus tropicalis)


name: PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Schizosaccharomyces pombe)


name: nonan-1-ol + hexadecanoyl-CoA = nonyl hexadecanoate + CoA


name: AMBRA1 binds DYNLL1,DYNLL2 (Homo sapiens)


name: VEGF-activated neuropilin signaling pathway involved in axon guidance


name: DHODH:FMN oxidises (S)-DHO to orotate (Plasmodium falciparum)


name: L-rhamnono-1,4-lactone + NADH + H(+) => L-rhamnofuranose + NAD(+)


name: (2S)-hesperidin + H2O <=> rutinose + (2S)-hesperetin


name: Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Rattus norvegicus)


name: Fusion of COPII vesicle with Golgi complex (Mus musculus)


name: mycophenolate + UDP-alpha-D-glucuronate <=> mycophenolate 7-O-beta-D-glucuronide + UDP + H(+)


name: PKR binds activating host RNA (Xenopus tropicalis)


name: miR-205 microRNA binds PTEN mRNA (Homo sapiens)


name: IDH2 dimer decarboxylates isocitrate (Sus scrofa)


name: 1,2-didecanoyl-sn-glycero-3-phosphocholine + H2O => 1,2-didecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: (E)-cinnamoyl-CoA + NADPH + H(+) => (E)-cinnamaldehyde + NADP(+) + CoA


name: pyruvate + NH4(+) => 2-iminopropanoate + H2O


name: indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose <=> (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + UDP + H(+)


name: Activated NTRK3 binds SRC (Gallus gallus)


name: Formation of HIF:CBP:p300 complex at promoters (Sus scrofa)


name: 1D-myo-inositol 1,2,3,4,5-pentakisphosphate + ATP = 3-diphospho-1D-myo-inositol 1,2,4,5-tetrakisphosphate + ADP


name: androst-4-ene-3,17-dione + acetate + NADP(+) + H2O => 17alpha-hydroxyprogesterone + NADPH + O2


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-CRKL:RAPGEF1:phospho-SHC1 binds GRB2:VAV1 (Sus scrofa)


name: N-terminal L-(Asp/Glu)3-[protein] + acetyl-CoA => N-terminal N-acetyl-L-(Asp/Glu)3-[protein] + CoA + H(+)


name: regulation of chaperonin ATPase activity


name: E2F1/2/3 stimulates EZH2 transcription (Homo sapiens)


name: butanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein]


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Sus scrofa)


name: Cohesin binding to decondensed chromatin is facilitated by NIPBL:MAU2 (Rattus norvegicus)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Homo sapiens)


name: ZC3H12A binds CDH19 gene promoter (Homo sapiens)


name: Docking of Mature Histone mRNA complex:TAP at the NPC (Gallus gallus)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Mus musculus)


name: preaustinoid A1 + 2-oxoglutarate + O2 <=> preaustinoid A2 + succinate + CO2 + H2O


name: 2-(prostaglandin G2)-sn-glycero-3-phosphoethanolamine => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 2 O2


name: (2E,6E)-farnesyl diphosphate = alpha-humulene + diphosphate


name: (2E)-geranyl diphosphate = beta-pinene + diphosphate


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Rattus norvegicus)


name: Recruitment of GRB2:SOS to p-5Y-LAT (Sus scrofa)


name: sBAFF,sAPRIL binds TACI,BCMA (Homo sapiens)


name: G or G analog binds C-ter TLR7 dimer (Sus scrofa)


name: gentamicin C + acetyl-CoA <=> N(3)-acetylgentamycin C + CoA + H(+)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Homo sapiens)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose <=> a 1,2-diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + UDP + H(+)


name: TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Caenorhabditis elegans)


name: NAD(+) => ADP-1-deoxy-1,O(4)-didehydro-D-ribose + nicotinamide


name: Activation of Ca-permeable Kainate receptors (Gallus gallus)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Drosophila melanogaster)


name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Sus scrofa)


name: arogenate dehydrogenase [NAD(P)+] activity


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Dictyostelium discoideum)


name: a 2-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine => a 2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine


name: Exocytosis of specific granule membrane proteins (Mus musculus)


name: 9,9',15-tri-cis-zeta-carotene + a plastoquinol => 15,9'-di-cis-phytofluene + a plastoquinone


name: Phosphorylation of APC component of the destruction complex (Sus scrofa)


name: chrysophanol + H2O => chrysophanol-9-anthrone + O2


name: MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)


name: (9Z,12Z)-octadecadienoate + O2 = 13-hydroperoxy-(9Z,11E)-octadecadienoate


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Plasmodium falciparum)


name: G alpha-olf:GTP binds to Gi alpha1:GTP:adenylate cyclase complex (Canis familiaris)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Danio rerio)


name: Recruitment of VAV and BTK to p-SLP-76 (Canis familiaris)


name: a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] => S-methyl-L-cysteinyl-[protein] + a 2'-deoxyguanosine in DNA


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Gallus gallus)


name: alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ (GLUD1,2) (Danio rerio)


name: ATG12 binds ATG7 dimer (Drosophila melanogaster)


name: sucrose 6(G)-phosphate(in) + L-histidyl-[protein] => N(pros)-phospho-L-histidyl-[protein](out) + sucrose


name: SLC26A3,6 exchange Cl- for HCO3- (Gallus gallus)


name: sucrose + H2O => beta-D-fructose + alpha-D-glucose


name: HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP (Homo sapiens)


name: NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Schizosaccharomyces pombe)


name: MAP2Ks and MAPKs bind to the activated RAF complex (Gallus gallus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Caenorhabditis elegans)


name: alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A (E. coli) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + a 1,2-diacyl-sn-glycerol


name: kainate(in) + ATP + H2O => kainate(out) + ADP + phosphate + H(+)


name: I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Bos taurus)


name: (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Xenopus tropicalis)


name: bis(myo-inositol) 1,3'-phosphate + 2 GDP-alpha-D-mannose <=> 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + 2 GDP + 2 H(+)


name: dihydroxyacetone phosphate <=> D-glyceraldehyde 3-phosphate (Caenorhabditis elegans)


name: a 3'-hydroxyflavone + S-adenosyl-L-methionine => a 3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: type 1 parathyroid hormone receptor ligand


name: SUCLG1/A2 cleaves succinyl-CoA (Drosophila melanogaster)


name: beta-catenin destruction complex assembly


name: UGT2B7,2B17,1A3 glucuronidates PRED metabolites (Bos taurus)


name: RUNX1:CBFB binds the LIFR gene promoter (Homo sapiens)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole => 12-epi-hapalindole U


name: chenodeoxycholoyl-24-O-(beta-D-glucuronate) + UDP => chenodeoxycholate + UDP-alpha-D-glucuronate


name: octadecanoate + O2 <=> (2R)-2-hydroperoxyoctadecanoate


name: ergosterol + UDP-alpha-D-glucose = ergosteryl 3-beta-D-glucoside + UDP + H(+)


name: Ni(II)-pyridinium-3,5-bisthiocarboxylate mononucleotide => pyridinium-3,5-bisthiocarboxylate mononucleotide + Ni(2+)


name: (7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (2E,6E)-farnesyl diphosphate = (S,S)-drim-8-en-11-yl diphosphate


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + L-serine => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoserine + ethanolamine


name: CDP-2,3-bis-O-(phytanyl)-sn-glycerol + L-serine => 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine + CMP + H(+)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Mus musculus)


name: AK4 phosphorylates (d)NMPs to (d)NDPs (Rattus norvegicus)


name: deoxyviolacein + CO2 + H2O => deoxyviolaceinate + O2 + H(+)


name: sulfite + UDP-alpha-D-glucose + H(+) => UDP-alpha-D-6-sulfoquinovose + H2O


name: activation of oligonucleate 5'-nucleotidohydrolase activity


name: L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate


name: PG and CDP-DAG are converted to CL by CRLS1 (Schizosaccharomyces pombe)


name: 3 ATP = 2',3',3'-c-tri-AMP + 3 diphosphate


name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (Mus musculus)


name: RHOA GEFs activate RHOA (Caenorhabditis elegans)


name: 3-oxosphinganine + eicosanoyl-CoA => N-eicosanoyl-3-oxosphinganine + CoA + H(+)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycerol + phosphoethanolamine + H(+)


name: CAD hexamer transforms CAP to N-carb-L-Asp (Plasmodium falciparum)


name: a hydroperoxyeicosatetraenoate <=> an oxoeicosatetraenoate + H2O


name: Ub-unfolded protein:(GlcNAc)2 (Man)9-5 translocates from ERQC to cytosol (Rattus norvegicus)


name: PM20D1 hydrolyzes oleoyl-phe (Xenopus tropicalis)


name: UMPS dimer transfers phosphoribosyl group to ORO to form OMP (Mus musculus)


name: ME1 tetramer decarboxylates MAL to PYR (Bos taurus)


name: (2E,6E)-farnesyl diphosphate => alpha-zingiberene + diphosphate


name: UGT1A3 lactonizes ATV to ATVL (Bos taurus)


name: Formation of MCM2-7 complex (Danio rerio)


name: RHAG transports CO2 from cytosol to extracellular region (Gallus gallus)


name: 23S rRNA (guanine(748)-N(1))-methyltransferase activity


name: E2F6:TFDP1:EPC1 binds the PRC2 complex (Rattus norvegicus)


name: MRN and RBBP8 resect DNA DSBs in MMEJ (Schizosaccharomyces pombe)


name: adenosine 3',5'-bisphosphate(in) + ADP(out) = adenosine 3',5'-bisphosphate(out) + ADP(in)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: F inhibitors bind F on RSV virion (Homo sapiens)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (13E)-labda-7,13-dien-15-yl diphosphate


name: VKORC1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone) (Drosophila melanogaster)


name: JMJD6 demethylates Me2R3-histone H3 (Sus scrofa)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-(acyl)-lipid IVA + a fatty acyl-[ACP] <=> an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + holo-[ACP]


name: RNA Pol II initiates transcription from damaged DNA template (Rattus norvegicus)


name: decanal + NADP(+) = (2E)-decenal + NADPH + H(+)


name: (20S)-protopanaxadiol + UDP-alpha-D-glucose <=> (20S)-ginsenoside Rh2 + UDP + H(+)


name: PG and CDP-DAG are converted to CL by CRLS1 (Homo sapiens)


name: 4,4-dihydroxy-all-trans-beta-carotene = echinenone + H2O


name: 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-xylose <=> 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + UDP + H(+)


name: Collagen type VIII degradation by MMP1 (Rattus norvegicus)


name: SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Gallus gallus)


name: N(alpha)-methyl-L-tryptophan + S-adenosyl-L-homocysteine + H(+) => L-tryptophan + S-adenosyl-L-methionine


name: 2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ (Gallus gallus)


name: 1-hexadecanoyl-2-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: p-S207 KARS displaces HINT1 (Drosophila melanogaster)


name: taurine + 2-oxoglutarate + O2 = aminoacetaldehyde + sulfite + succinate + CO2 + H(+)


name: Autocatalytic activation of MMP1 (Homo sapiens)


name: inhibition of activation of JAK2 kinase activity


name: octanoate + NADPH + 2 H(+) => octanal + NADP(+) + H2O


name: ATF6B (ATF6-beta) translocates from the cytosol to the nucleus (Canis familiaris)


name: 2-oxoglutarate + NADP(+) + CoA = succinyl-CoA + CO2 + NADPH


name: triphosphate + H2O = phosphate + diphosphate


name: D-mannose(out) + H(+)(out) = D-mannose(in) + H(+)(in)


name: PTGS2 dimer binds PTGS2 inhibitors (Rattus norvegicus)


name: taxa-4(20),11-dien-5alpha-ol + reduced [NADPH--hemoprotein reductase] + O2 => taxa-4(20),11-dien-5alpha,13alpha-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: eicosanoyl-CoA + 2 malonyl-CoA + 2 H(+) => 4-hydroxy-6-nonadecylpyran-2-one + 2 CO2 + 3 CoA


name: CIDEA:CIDEC binds lipid droplets (Canis familiaris)


name: gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling


name: 1,2-diacyl-glycerol + acyl-CoA => triacylglycerol + CoASH [DGAT2] (Mus musculus)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Gallus gallus)


name: NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Schizosaccharomyces pombe)


name: Secreted ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)


name: cyclo(L-arginyl-(Z)-dehydro-3,4-dihydroxytyrosyl) + A + H2O => cyclo(L-arginyl-L-dehydrotyrosyl) + AH2 + O2


name: MTRR reduces cob(II)alamin to meCbl (Canis familiaris)


name: Connexin 45/Connexin 36 mediated neuronal gap junction communication (Xenopus tropicalis)


name: 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in) => 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out)


name: Adenylate cyclase converts ATP into cyclic AMP (Gallus gallus)


name: AKT1 phosphorylates eNOS (Rattus norvegicus)


name: S-adenosyl 3-(methylsulfanyl)propylamine + propane-1,3-diamine = norspermidine + S-methyl-5'-thioadenosine + H(+)


name: dihydrochanoclavine-I aldehyde = 6,8-dimethyl-6,7-didehydroergoline + H2O


name: MAN2C1 hydrolyses GlcNAc (Man)9 to GlcNAc (Man)5 (Rattus norvegicus)


name: a 16alpha-hydroxysteroid = a 16beta-hydroxysteroid


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Homo sapiens)


name: RBP3 regulates atROL taken up by Muller cells (Mus musculus)


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Bos taurus)


name: a long-chain fatty acyl-CoA + acetyl-CoA => a long-chain 3-oxo-fatty acyl-CoA + CoA


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Homo sapiens)


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA <=> 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-D-myo-inositol + CoA


name: 3-phenylpyruvate + L-kynurenine => kynurenate + L-phenylalanine + H2O


name: an aldehyde + 2 Fe(III)-[cytochrome c] + H2O = a carboxylate + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: 3',5'-cyclic GMP(out) + ADP + phosphate + H(+) => 3',5'-cyclic GMP(in) + ATP + H2O


name: (1S,2S,4R)-endo-fenchol + NAD(+) => (1S,4R)-fenchone + NADH + H(+)


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 => 1-O-methyl-(9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: PKC autophosphorylates (Caenorhabditis elegans)


name: bromide + 4-hydroxybenzoate + NADPH + O2 + 2 H(+) => 3-bromo-4-hydroxybenzoate + NADP(+) + 2 H2O


name: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)


name: typhasterol + reduced [NADPH--hemoprotein reductase] + O2 => 7-oxatyphasterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: cob(II)yrinate a,c diamide + apo-[corrinoid adenosyltransferase] => cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase]


name: CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane (Rattus norvegicus)


name: inhibition of CTP:diacylglycerol kinase activity


name: prostaglandin E1(in) => prostaglandin E1(out)


name: guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine (Mus musculus)


name: HEXA cleaves the terminal GalNAc from small HA fragments (Canis familiaris)


name: N-acetyl-D-muramate 6-phosphate + H2O => N-acetyl-D-glucosamine 6-phosphate + (R)-lactate


name: Dehalogenation of carbon tetrachloride to form a free radical (Mus musculus)


name: 4a-hydroxytetrahydrobiopterin => q-dihydrobiopterin + H2O (Xenopus tropicalis)


name: RNF144A polyubiquitinates PRKDC (Gallus gallus)


name: (1R,3R)-chrysanthemal + NAD(+) + H2O = (1R,3R)-chrysanthemate + NADH + 2 H(+)


name: hydroxypyruvate reductase (NADPH) activity


name: octan-1-ol + NADP(+) = octanal + NADPH + H(+)


name: Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Drosophila melanogaster)


name: DNA 5'-adenosine monophosphate hydrolase activity


name: biotin(in) + ATP + H2O <=> biotin(out) + ADP + phosphate + H(+)


name: 3,5-dihydroxybenzaldehyde + 4-hydroxybenzaldehyde => trans-resveratrol + O2


name: cAMP degradation by Phosphodiesterases (Mus musculus)


name: GDP-D-glucose + (2R)-3-phosphoglycerate <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + GDP + H(+)


name: (R)-mevaldate + NADH + H(+) => (R)-mevalonate + NAD(+)


name: ursocholate + NADP(+) <=> 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADPH + H(+)


name: CDKN1A gene expression is synergistically activated by RUNX3, SMAD3 and SMAD4 (Homo sapiens)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = 1,2-dihexadecanoyl-sn-glycerol + phosphoethanolamine + H(+)


name: soppiline B + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 <=> soppiline C + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: cell surface bile acid receptor signaling pathway


name: Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Homo sapiens)


name: HTR1A binds HTR1A antagonists (Caenorhabditis elegans)


name: an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate => an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)


name: FDPS dimer transfers IPPP to GPP (Caenorhabditis elegans)


name: PIP3 recruits AKT to the membrane (Schizosaccharomyces pombe)


name: chenodeoxycholoyl-CoA + glycine = glycochenodeoxycholate + CoA + H(+)


name: SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Canis familiaris)


name: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP + H(+)


name: CD200 binds to CD200R (Rattus norvegicus)


name: PLK1 phosphorylates NUDC (Caenorhabditis elegans)


name: sn-glycerol 3-phosphate + an acyl-CoA => a 1-acyl-sn-glycero-3-phosphate + CoA


name: 1-eicosanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA <=> 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA


name: SUMOylation of ING2 with SUMO1 (Danio rerio)


name: Ragulator binds Rag dimers (Canis familiaris)


name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Canis familiaris)


name: a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + 2 S-adenosyl-L-homocysteine => a 5'-end 5'-phospho-ribonucleoside-RNA + 2 S-adenosyl-L-methionine


name: Phosphorylation of IL2RB Y338, Y392 or Y510 enables STAT recruitment (Sus scrofa)


name: [aequorin] + 3 Ca(2+) => [aequorin]--dioxetanone


name: Potassium voltage-gated channels close in reponse to PKA (Rattus norvegicus)


name: D-glucuronate(out) + H(+)(out) => D-glucuronate(in) + H(+)(in)


name: Polyubiquitinated RUNX3 is degraded by the proteasome (Drosophila melanogaster)


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3A (GRIN3A) (Xenopus tropicalis)


name: a 5'-end triphospho-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + GDP + H(+) <=> a 5'-end (5'-triphosphoguanosine)-adenylyl-adenylyl-cytidylyl-adenosine in mRNA + diphosphate


name: a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-guanosine in mRNA + H2O <=> a 5'-end phospho-guanosine in mRNA + N(2),N(2),N(7)-trimethyl-GDP + 2 H(+)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Saccharomyces cerevisiae)


name: DAG kinase produces phosphatidic acid from DAG (Dictyostelium discoideum)


name: Formation of Cyclin A:Cdc2 complexes (Xenopus tropicalis)


name: N(1)-acetylspermidine + 3-aminopropanal + H2O2 => N(1)-acetylspermine + O2 + H2O


name: SCF-FBXL7 ubiquitinates AURKA (Mus musculus)


name: Exocytosis of ficolin-rich granule lumen proteins (Dictyostelium discoideum)


name: D-ribose 5-phosphate + ATP <=> alpha-D-ribose 1,5-bisphosphate + ADP + H(+)


name: GDP-6-deoxy-alpha-D-talose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)


name: Autophosphorylation of PDGF beta receptors (Canis familiaris)


name: all-trans-zeaxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = all-trans-antheraxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: tetradecanoate + ATP + CoA => tetradecanoyl-CoA + AMP + diphosphate


name: (S)-malate + NADP(+) <=> pyruvate + CO2 + NADPH


name: taurine(out) + chloride(out) + 2 Na(+)(out) = taurine(in) + chloride(in) + 2 Na(+)(in)


name: MYLIP dimer ubiquitinates VLDLR on Lys-839 (Bos taurus)


name: phosphinomethylmalate => 2-(phosphinatomethylidene)butanedioate + H2O


name: tRNA(n) + a ribonucleoside 5'-diphosphate => tRNA(n+1) + phosphate


name: UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Mus musculus)


name: 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 8,12-diethyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-homocysteine + H(+)


name: (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + O2 <=> (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole-[protein] + H2O2


name: positive regulation of interleukin-17-mediated signaling pathway


name: 2-acyl LPG is acylated to PG by LPGAT (Dictyostelium discoideum)


name: N-formimidoyl-L-glutamate + H2O => N-formyl-L-glutamate + NH4(+)


name: PDE3A hydrolyses cAMP to AMP (Gallus gallus)


name: Recruitment of p190RhoGEF to p-FAK (Homo sapiens)


name: PNPLA4 hydrolyzes TAG (Rattus norvegicus)


name: β1,2-agonists bind ADRB1,2 (Mus musculus)


name: (E)-cinnamoyl-CoA + 3 malonyl-CoA + 3 H(+) <=> (E)-pinosylvin + 4 CO2 + 4 CoA


name: (2E,6E)-farnesyl diphosphate + H2O => (-)-alpha-acorenol + diphosphate


name: 3-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine


name: (2R)-3-phosphoglycerate + UDP-alpha-D-glucose <=> (2R)-2-O-(alpha-D-glucopyranosyl)-3-phospho-glycerate + UDP + H(+)


name: Dephosphorylation of Gab1 by SHP2 (Gallus gallus)


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Rattus norvegicus)


name: GNMT tetramer transfers methyl group from AdoMet to Gly to form AdoHyc and SARC (Drosophila melanogaster)


name: (9Z,12Z,15Z)-octadecatrienoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-(9Z-octadecaenoyl)-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + CoA


name: 1,2-dichloroethane + H2O <=> 2-chloroethanol + chloride + H(+)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Mus musculus)


name: CaMKK autophosphorylates in the cytosol (Rattus norvegicus)


name: Phosphorylated BLNK (SLP65, in Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1) binds BTK, PLCG2, VAV1, NCK1 (Canis familiaris)


name: 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: muscarinic acetylcholine receptor ligand


name: SALL4 binds the SALL4 promoter (Homo sapiens)


name: 16alpha,17alpha-dihydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 6beta,16alpha,17alpha-trihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: thiosulfate(out) + ATP + H2O <=> thiosulfate(in) + ADP + phosphate + H(+)


name: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate + 2 H(+)


name: HNF1B binds the IRX1 gene (Homo sapiens)


name: vasoactive intestinal polypeptide receptor activity


name: Beta-catenin recruits CDC73 and LEO1 (Gallus gallus)


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + D-serine + H2O = alpha-(hydroxymethyl)serine + (6S)-5,6,7,8-tetrahydrofolate


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Sus scrofa)


name: CALHM1:CALHM3 transports ATP from the cytosol to the extracellular region (Homo sapiens)


name: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds


name: 3-dehydro-4alpha-methylzymosterol + NADPH + H(+) => 4alpha-methylzymosterol + NADP(+)


name: RNA polymerase II C-terminal domain binding


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O => (6E,10E)-geranyllinalool + diphosphate


name: 5,6-dihydrouracil + NAD(+) = uracil + NADH + H(+)


name: succinate + CoASH + ATP <=> succinylCoA + ADP + Pi (Gallus gallus)


name: variecolorin G + diphosphate => neoechinulin A + dimethylallyl diphosphate


name: Growing HA is extruded from the cell by ABCC5 (Homo sapiens)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine <=> 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine


name: 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity


name: SEMA4D interacts with CD45 (Drosophila melanogaster)


name: Formation of HIF:CBP:p300 complex at promoters (Rattus norvegicus)


name: glutarate + ATP + CoA => glutaryl-CoA + ADP + phosphate


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Homo sapiens)


name: Pregnenolone translocates from the mitochondrial matrix to the cytosol (Homo sapiens)


name: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen (Mus musculus)


name: GOPC promotes translocation of CFTR to lysosomes (Sus scrofa)


name: FNTB inhibitors bind FNTA:FNTB (Saccharomyces cerevisiae)


name: STAT1,STAT3,STAT6 phosphorylation (Gallus gallus)


name: ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Canis familiaris)


name: CDC42:GTP binds PAK2 (Xenopus tropicalis)


name: UDP-alpha-D-xylose(in) + UMP(out) <=> UDP-alpha-D-xylose(out) + UMP(in)


name: SREBP1A,1C,2 translocates to the nucleus (Bos taurus)


name: Aggresome dissociates from dynein and microtubule (Mus musculus)


name: Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Homo sapiens)


name: UNC119B binds myristoylated proteins (Danio rerio)


name: Phosphorylation of Cx43 by c-src (Sus scrofa)


name: a sphingoid 1-phosphate => a fatty aldehyde + phosphoethanolamine


name: 2xRANK binds RANKL,sRANKL trimer:RANK (Gallus gallus)


name: (S)-methylmalonyl-CoA + Na(+)(in) + H(+)(out) = propanoyl-CoA + Na(+)(out) + CO2


name: alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Xenopus tropicalis)


name: 2,4-dinitrotoluene + NADH + O2 = 4-methyl-5-nitrocatechol + nitrite + NAD(+)


name: Recruitment of GRB2:SOS1 to phosphorylated SHC1 in complex with phosphorylated ERBB4 homodimers (Canis familiaris)


name: 14-3-3epsilon attentuates NADE-related apoptosis (Sus scrofa)


name: ethyl 3-oxohexanoate + NADPH + H(+) => ethyl (S)-3-hydroxyhexanoate + NADP(+)


name: high affinity ferric uptake transmembrane transporter activity


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Bos taurus)


name: gamma-L-glutamyl-butirosin B + holo-[BtrI ACP] + H(+) => 4-(gamma-L-glutamylamino)-(2S)-2-hydroxybutanoyl-[BtrI ACP] + ribostamycin


name: Beta-catenin translocates to the nucleus (Danio rerio)


name: Procollagen lysyl hydroxylases convert collagen lysines to 5-hydroxylysines (Caenorhabditis elegans)


name: FOXO3 translocates from the mitochondrial matrix to the nucleus (Gallus gallus)


name: Phosphorylation of LIMK-1 by PAK (Bos taurus)


name: ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Xenopus tropicalis)


name: Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 1 (Homo sapiens)


name: D-loop extension by DNA polymerases (Sus scrofa)


name: PPT1 hydrolyses palmitoylated proteins (Homo sapiens)


name: a 1-O-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H(+) => 1-O-alkyl-2-acyl-sn-glycerol + CDP-ethanolamine


name: a 1-(1,2-saturated alkyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2


name: Increased Central Nervous System Epinephrine Activity


name: 1,2-di-(9Z,12Z-octadecadienoyl)-3-beta-D-galactosyl-sn-glycerol + UDP + H(+) => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + UDP-alpha-D-galactose


name: 3-oxo-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADPH + H(+) <=> (3R)-hydroxy-(17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + NADP(+)


name: 2-phenylacetaldehyde + CO2 => 3-phenylpyruvate + H(+)


name: "3,8-divinyl protochlorophyllide a 8-vinyl-reductase (ferredoxin)"


name: dUTP + 2 H2O <=> dUMP + 2 phosphate + 2 H(+)


name: LIG1 binds APEX1 and PCNA at SSB (Homo sapiens)


name: N-(9Z-octadecenoyl)-sphing-4-enine + UDP-alpha-D-xylose = beta-D-xylosyl-(1<->1')-N-(9Z-octadecenoyl)-sphing-4-enine + UDP + H(+)


name: a 2,3-bis-O-phytanyl-sn-glycerol 1-phospholipid + 8 A => a 2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phospholipid + 8 AH2


name: positive regulation of chaperone activity


name: Serotonin loaded synaptic vesicle docking and priming (Homo sapiens)


name: Activated FGFR3 binds FRS2 (Homo sapiens)


name: 2-sulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: CBL ubiquitinates FRS2 and FGFR2 (Gallus gallus)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Rattus norvegicus)


name: histidine => urocanate + NH4+ (Homo sapiens)


name: TSPO:BZRAP1 transports CHOL from outer mitochondrial membrane to inner mitochondrial membrane (Homo sapiens)


name: MMAB adenosylates cob(I)alamin (Rattus norvegicus)


name: 2-[(E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amino]acetate + H2O2 + H(+) => N-(1-deoxy-beta-D-fructopyranos-1-yl)glycine + O2


name: Activation of Rap1 by cytosolic GEFs (Mus musculus)


name: RAP1A exchanges GDP for GTP (Saccharomyces cerevisiae)


name: GAT1-3 mediate Na+/Cl- dependent GABA transport (Drosophila melanogaster)


name: 2-thiocytidine 5'-phosphate + ADP + H(+) => 2-thiocytidine + ATP


name: Phosphorylation of RAF (Rattus norvegicus)


name: Protein kinase C, alpha type phosphorylates MARCKS (Homo sapiens)


name: Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA (Rattus norvegicus)


name: 25(S) THCA-CoA is dehydrogenated to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) (Bos taurus)


name: PAK1 phosphorylates LIMK1 (Gallus gallus)


name: L-aspartate(89)-[ribosomal protein uS12]-hydrogen + [sulfur carrier]-SH + S-adenosyl-L-methionine = L-aspartate(89)-[ribosomal protein uS12]-methanesulfate + [sulfur carrier]-H + S-adenosyl-L-homocysteine + H(+)


name: RAB43 hydrolyses GTP (Schizosaccharomyces pombe)


name: CDC42 binds effectors at the ER membrane (Homo sapiens)


name: a 12-hydroxyjasmonate + 3'-phosphoadenylyl sulfate => a 12-sulfojasmonate + adenosine 3',5'-bisphosphate + H(+)


name: The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Rattus norvegicus)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O => 1-O-(1Z-alkenyl)-sn-glycerol + phosphoethanolamine + H(+)


name: p-Y705-STAT3 dissociates from  IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:p-Y705-STAT3 (Gallus gallus)


name: HSP90:FKBP4:PTGES3 binds HSF1 trimer (Gallus gallus)


name: GLI3R translocates to the nucleus (Sus scrofa)


name: a 3-oxoacyl-CoA + NADH + H(+) => a (3R)-3-hydroxyacyl-CoA + NAD(+)


name: 6-deoxycathasterone + reduced [NADPH--hemoprotein reductase] + O2 = (22S,24R)-22-hydroxy-5alpha-ergostan-3-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: 1,2-dihexadecanoyl-sn-glycero-3-CDP + myo-inositol <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)


name: benzaldehyde + AMP + diphosphate + NADP(+) => benzoate + ATP + NADPH + H(+)


name: ASIC trimers bind H+ (Caenorhabditis elegans)


name: (1R,2S,4R)-neodihydrocarveol + NAD(+) => (1R,4R)-dihydrocarvone + NADH + H(+)


name: p-PKR dimer phosphorylates DHX9 (Bos taurus)


name: Proteasome mediated degradation of Cyclin D1 (Gallus gallus)


name: RHOB:GTP recruits DIAPH1 or DIAPH3 to endosomes (Caenorhabditis elegans)


name: IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Canis familiaris)


name: L-glutamate + ADP + phosphate + H(+) => 5-oxo-L-proline + ATP + 2 H2O


name: PRKN ubiquitinates MOM substrates (Homo sapiens)


name: tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity


name: aculene B + holo-[peptidyl-carrier protein] => aculene D + L-prolyl-[peptidyl-carrier protein]


name: L-ectoine(out) + ATP + H2O => L-ectoine(in) + ADP + phosphate + H(+)


name: NuRD complex binds SUMO2-6K-TRIM28:KRAB-ZNF:retroelement (Homo sapiens)


name: p-T182 MAPKAPK5 binds DNAJB1 (Rattus norvegicus)


name: Integrator complex processes the 3' end of snRNA (Homo sapiens)


name: Active G alpha (q) binds RGS proteins (Drosophila melanogaster)


name: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H(+)


name: AKT interacts and phosphorylates Cot (Homo sapiens)


name: 1,2-dioctanoyl-3-O-beta-D-galactosyl-sn-glycerol + H2O = 2-octanoyl-3-O-beta-D-galactosyl-sn-glycerol + octanoate + H(+)


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Xenopus tropicalis)


name: 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA => a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA


name: an aliphatic sulfonate + 4 oxidized [4Fe-4S]-[ferredoxin] + 2 H2O <=> 4 reduced [4Fe-4S]-[ferredoxin] + a carboxylate + sulfite + 6 H(+)


name: O-acetyl-(R)-carnitine + CoA => (R)-carnitine + acetyl-CoA


name: peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine


name: PXLP-SGPL1 cleaves sphingoid-1-phosphates (Drosophila melanogaster)


name: Activated MET recruits GRB2-1:SOS1 (Homo sapiens)


name: corticosterone + NAD(+) <=> 11-dehydrocorticosterone + NADH + H(+)


name: negative regulation of caspase activation


name: Formation of the preholothymoproteasome (Homo sapiens)


name: alpha-D-glucose 6-phosphate + H2O => alpha-D-glucose + phosphate


name: MMACHC dealkylates RCbl (Rattus norvegicus)


name: Hh-dependent expression of GLI1 gene (Homo sapiens)


name: PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Xenopus tropicalis)


name: [phosphate](n+1) + UDP => [phosphate](n) + UTP


name: 3-oxo-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADPH + H(+) => (3R)-hydroxy-(12Z,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADP(+)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Canis familiaris)


name: Phosphorylation of cPLA2 by ERK-2 (Mus musculus)


name: KIR3DL1 interacting with HLA Bw4 (Rattus norvegicus)


name: L-cystine(out) + H(+)(out) = L-cystine(in) + H(+)(in)


name: WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Caenorhabditis elegans)


name: 4-hydroxynonanal + NADP(+) = (E)-4-hydroxynon-2-enal + NADPH + H(+)


name: Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2 (Homo sapiens)


name: acetaldehyde + NAD+ => acetate + NADH + H+ [mitochondrial] (Mus musculus)


name: S-farn Me-HRAS, -NRAS and -KRAS4A are palmitoylated (Sus scrofa)


name: Formation of Elongin complex (Homo sapiens)


name: PHF20 binds TP53 dimethylated on K370 and K382 (Sus scrofa)


name: EPHX1 hydrates BaP4,5O to BaP4,5-DHD (Drosophila melanogaster)


name: Factor H binds to membrane-associated C3b (Canis familiaris)


name: p-Y705-STAT3,p-Y641-STAT6 dissociate (Sus scrofa)


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Homo sapiens)


name: (2E,6E)-farnesol + NADP(+) = (2E,6E)-farnesal + NADPH + H(+)


name: (2S)-3-sulfolactaldehyde + NAD(+) + H2O <=> (2S)-3-sulfolactate + NADH + 2 H(+)


name: O-succinyl-L-homoserine + hydrogen sulfide <=> L-homocysteine + succinate


name: acetate + malonyl-CoA => malonate + acetyl-CoA


name: ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)


name: zinc efflux active transmembrane transporter activity


name: Recruitment of clathrin coated vesicle by Ii (Rattus norvegicus)


name: C3a receptor binds anaphylatoxin C3a (Xenopus tropicalis)


name: Auto-ubiquitination of TRAF3 within activated TLR3 complex (Homo sapiens)


name: 6 malonyl-CoA + NADH + 5 NADPH + 12 H(+) => (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + 6 CO2 + NAD(+) + 5 NADP(+) + 6 CoA + 4 H2O


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoserine + ethanolamine


name: TAX1BP1:A20 inhibit TBK1/IKKi K63-polyubiquitination (Rattus norvegicus)


name: CYP21A2 oxidises 17HPROG (Canis familiaris)


name: 2xTPK1:Mg2+ phosphorylates THMN (Sus scrofa)


name: Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Caenorhabditis elegans)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Homo sapiens)


name: Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex (Gallus gallus)


name: enterobactin(in) + H(+)(out) => enterobactin(out) + H(+)(in)


name: 2'-deamino-2'-hydroxyneamine + 2-oxoglutarate = 2'-deamino-2'-hydroxy-6'-dehydroparomamine + L-glutamate


name: 1D-myo-inositol 3-phosphate => D-glucose 6-phosphate


name: FABP5:atRA translocates from cytosol to nucleoplasm (Homo sapiens)


name: Spermine  => N-acetylated spermine (Drosophila melanogaster)


name: Gi activation by P2Y purinoceptor 12 (Sus scrofa)


name: glycine(in) + H(+)(in) = glycine(out) + H(+)(out)


name: bis(beta-D-glucosyl) crocetin + UDP-alpha-D-glucose => beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP + H(+)


name: Furin cleaves pro-GAS6 to GAS6 (Bos taurus)


name: amidinoproclavaminate + H2O <=> proclavaminate + urea


name: (13R)-hydroxy-(9Z,11E)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2


name: DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Caenorhabditis elegans)


name: (S)-lactate + oxaloacetate <=> (S)-malate + pyruvate


name: DARC  is a non-specific receptor for many chemokines (Canis familiaris)


name: CYP2F1 dehydrogenates 3-methylindole (Danio rerio)


name: oxidized coenzyme F420-(gamma-L-Glu)(n) + H2 + H(+) = reduced coenzyme F420-(gamma-L-Glu)(n)


name: PSIP1 binds MLL1 and MEN1 (Drosophila melanogaster)


name: 1-tetracosanoylglycerol + H2O = tetracosanoate + glycerol + H(+)


name: nitroxyl + 2 Fe(II)-[cytochrome c] + 2 H(+) => hydroxylamine + 2 Fe(III)-[cytochrome c]


name: Non-covalent tyrosine kinase inhibitors bind and inactivate sensitive ligand-responsive EGFR cancer mutants (Homo sapiens)


name: oxalate + succinyl-CoA = oxalyl-CoA + succinate


name: alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity


name: starch (bacterial glycogen) synthase activity


name: Activation of Ca2+ activated Potassium channels with small conductance (Danio rerio)


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Caenorhabditis elegans)


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Caenorhabditis elegans)


name: Formation of CD8:Nef:AP-2 Complex:v-ATPase Complex (Homo sapiens)


name: MDC1 associates with gamma-H2AFX at nuclear foci (Mus musculus)


name: ATR phosphorylates RPA2 (Rattus norvegicus)


name: UDP-alpha-D-glucose + H2O => alpha-D-glucose 1-phosphate + UMP + 2 H(+)


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Canis familiaris)


name: N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + ADP = N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + AMP + H(+)


name: asperterpenoid C + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => asperterpenoid A + reduced [NADPH--hemoprotein reductase] + O2


name: methane + NADPH + O2 + H(+) => methanol + NADP(+) + H2O


name: PDK isozymes phosphorylate PDHC subunit E1 (Mus musculus)


name: Activation of Ca permeable AMPA receptors (Rattus norvegicus)


name: hydrazine + 4 Fe(III)-[cytochrome c] => N2 + 4 Fe(II)-[cytochrome c] + 4 H(+)


name: (R)-2-O-sulfolactate + H2O = (R)-lactate + sulfate + H(+)


name: deoxycholate + glycine => glycodeoxycholate + H2O


name: a 3'-end 2'-deoxyribonucleotide-DNA + phosphate => a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H2O


name: cGMP dissociates from CNG channels (Canis familiaris)


name: CNDP2:2Mn2+ dimer hydrolyses CysGly (Homo sapiens)


name: 3''-deamino-3''-oxonicotianamine + L-glutamate => nicotianamine + 2-oxoglutarate


name: low voltage-dependent potassium channel auxiliary protein activity


name: ATG12 forms a thioester bond with ATG7 dimer (Homo sapiens)


name: ACLY tetramer transforms CIT to Ac-CoA (Caenorhabditis elegans)


name: heptanedioate(in) + 2-oxoglutarate(out) => heptanedioate(out) + 2-oxoglutarate(in)


name: vitamin B6 transmembrane transporter activity


name: a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-adenosine in mRNA + S-adenosyl-L-homocysteine


name: GUSB tetramer hydrolyses GlcA-β1,3-GlcNAc (Canis familiaris)


name: Increased Midbrain Brain Derived Neurotropic Activity


name: HMG CoA => acetoacetic acid + acetyl CoA (Dictyostelium discoideum)


name: (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate => (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2


name: Formation of collagen fibres (Rattus norvegicus)


name: SLC43A2 (LAT4)-mediated uptake of large neutral amino acids (Sus scrofa)


name: SARS-CoV-1 8b binds NLRP3 (Homo sapiens)


name: 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine => 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: Surface deployment of platelet alpha granule membrane components (Saccharomyces cerevisiae)


name: a 3-(acyloxy)acyl derivative of bacterial toxin + H2O <=> a 3-hydroxyacyl derivative of bacterial toxin + a fatty acid + H(+)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-2,3-cyclic phosphate + ethanolamine


name: Displacement of NTHL1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Rattus norvegicus)


name: (S)-phenylacetylcarbinol + NAD(+) <=> 1-phenyl-1,2-propanedione + NADH + H(+)


name: Liganded Gs-activating GPCR acts as a GEF for Gs (Homo sapiens)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Bos taurus)


name: activation of sulfate assimilation, phosphoadenylyl sulfate reduction by an oxidoreductase, acting on sulfur group of donors, NAD or NADP as acceptor


name: N-hexadecanoylsphinganine + beta-D-galactose => beta-D-galactosyl-(1<->1')-N-hexadecanoylsphinganine + H2O


name: down regulation of electron carrier, chlorophyll electron transport system


name: NEDD4L ubiquitinates SMAD2/3 (Bos taurus)


name: (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(1'-sn-glycerol) + (9Z)-octadecenoate + H(+) => (S,S)-2-(9Z-octadecenoyl)-sn-glycero-1-phospho-(2'-(9Z-octadecenoyl)-1'-sn-glycerol) + H2O


name: GTP <=> cyclic pyranopterin phosphate + diphosphate


name: ADORA2A,B bind Ade-Rib (Xenopus tropicalis)


name: Nonendonucleolytic RISC binds exactly matching target RNAs (Rattus norvegicus)


name: activation of xylose catabolic process to ethanol


name: 3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+)


name: an N-acylsphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol => an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Interaction of PECAM-1 and PLC gamma1 (Gallus gallus)


name: (3S)-citramalyl-CoA => pyruvate + acetyl-CoA


name: Loading of dopamine into synaptic veiscles (Gallus gallus)


name: L-lysine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-lysine + succinate + CO2


name: p-S225-SPHK1 localizes to cytosol (Saccharomyces cerevisiae)


name: heme b + 2 CO2 + 4 H2O => Fe-coproporphyrin III + 2 H2O2 + 2 H(+)


name: ARF4:GTP binds VxPx-motifs of membrane proteins (Drosophila melanogaster)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Mus musculus)


name: Aquaporin-4 passively transports water out of cell (Xenopus tropicalis)


name: 3-demethylubiquinol-8 + S-adenosyl-L-methionine = ubiquinol-8 + S-adenosyl-L-homocysteine + H(+)


name: (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + sarcosine + oxidized [electron-transfer flavoprotein] + H(+) = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + reduced [electron-transfer flavoprotein] + glycine


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O


name: 6-phospho-2-dehydro-D-gluconate + ADP + H(+) => 2-dehydro-D-gluconate + ATP


name: Defective NAGLU does not hydrolyse Heparan sulfate chain(4) (Homo sapiens)


name: TNF-α:TNFR1:NSMAF:GNB2L1 associates with SMPD2,3 (Sus scrofa)


name: N-hexadecanoylethanolamine + H2O => ethanolamine + hexadecanoate


name: dTTP + alpha-D-glucose 1-phosphate + H(+) => dTDP-alpha-D-glucose + diphosphate


name: Activation of TRESK (Drosophila melanogaster)


name: 2-(glutathion-S-yl)-2-(1H-indol-3-yl)acetonitrile + H2O <=> 2-(glycyl-L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + L-glutamate


name: peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine


name: propane-1,3-diol + NADP(+) = 3-hydroxypropanal + NADPH + H(+)


name: Pregn-5-ene-3,20-dione isomerizes to progesterone (Homo sapiens)


name: Interaction of Tie2 with Ang1 (Bos taurus)


name: LTA4H:Zn2+ hydrolyses 4S(5)-epoxy-17(S)-HDHA to RvD3 or RvD4 (Xenopus tropicalis)


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)


name: PITPNM1,2,3 exchange PI for PA (Canis familiaris)


name: a 5'-end phospho-ribonucleoside in snoRNA + NAD(+) + H(+) => a 5'-end NAD(+)-phospho-ribonucleoside in snoRNA + H2O


name: 2-oxoheptanedioate + CO2 + NADH => (2R,3S)-iso(homo)2citrate + NAD(+)


name: (14R,15S)-dihydroperoxy-(5Z,8Z,10E,12E)-eicosatetraenoate => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2


name: MECP2 binds RBFOX1 gene promoter (Homo sapiens)


name: IMPDH tetramers binds IMPDH inhibitors (Schizosaccharomyces pombe)


name: GPR31 is a receptor for 12(S)-HETE (Homo sapiens)


name: estrone 3-sulfate(out) <=> estrone 3-sulfate(in)


name: a flavonol + succinate + CO2 + H2O => a (2R,3R)-dihydroflavonol + 2-oxoglutarate + O2


name: HCCS inserts heme into cytochrome c (Saccharomyces cerevisiae)


name: JAK1,TYK2 phosphorylate JAK1,TYK2 (Canis familiaris)


name: Autophosphorylation of PKC-theta (Mus musculus)


name: Activated FGFR1:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Xenopus tropicalis)


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Sus scrofa)


name: activated MAPK3/MAPK6 migrates to nucleus (Gallus gallus)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)


name: single-organism carbohydrate catabolic process


name: GDNF,NRTN bind RET:GFRA1,GFRA2 (Sus scrofa)


name: tBID binds to inactive BAX protein (Rattus norvegicus)


name: didemethylasterriquinone D + dimethylallyl diphosphate = asterriquinone C1 + diphosphate


name: KLF5 gene expression is enhanced by CEBPA (Homo sapiens)


name: NR1H2,3 binds the EEPD1 gene (Homo sapiens)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Drosophila melanogaster)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-alanine + O2 = N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-alanine


name: SMAD7 binds to SMURF2 (Rattus norvegicus)


name: 3-oxopropanoate + H(+) <=> acetaldehyde + CO2


name: 2 4-coumaroyl-CoA + malonyl-CoA + H2O + H(+) = bisdemethoxycurcumin + 2 CO2 + 3 CoA


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA => 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + CoA


name: alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + dTDP-beta-L-rhamnose <=> alpha-L-rhamnosyl-(1->3)-alpha-D-galactosyl-1-diphospho-di-trans,octa-cis-undecaprenol + dTDP + H(+)


name: a 1-O-alkyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA <=> a 1-alkyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+)


name: USP7 deubiquitinates MDM2 (Rattus norvegicus)


name: (2E,6E)-omega-hydroxy-farnesyl diphosphate + NADP(+) + H2O => (2E,6E)-farnesyl diphosphate + NADPH + O2 + H(+)