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This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals."], "t": []}, {"i": "UMLS:C1817866", "l": "IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor", "d": [], "t": []}], "preferred_name": "IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C2256213", "l": "inhibition of response to tumor cell", "d": [], "t": []}], "preferred_name": "inhibition of response to tumor cell", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0045792", "l": "negative regulation of cell size", "d": ["Any process that reduces cell size."], "t": []}], "preferred_name": "negative regulation of cell size", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1901613", "l": "negative regulation of terminal button organization", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization."], "t": []}], "preferred_name": "negative regulation of terminal button organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "68.151380672051147", "identifiers": [{"i": "GO:0002573", "l": "myeloid leukocyte differentiation", "d": ["The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage."], "t": []}, {"i": "UMLS:C1818687", "l": "myeloid leukocyte differentiation", "d": [], "t": []}], "preferred_name": "myeloid leukocyte differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.76525123142531", "identifiers": [{"i": "GO:1904429", "l": "regulation of t-circle formation", "d": ["Any process that modulates the frequency, rate or extent of t-circle formation."], "t": []}, {"i": "UMLS:C4236094", "l": "regulation of t-circle formation", "d": [], "t": []}], "preferred_name": "regulation of t-circle formation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C3826539", "l": "Human skin color", "d": [], "t": []}], "preferred_name": "Human skin color", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C0334176", "l": "Acinar development of breast", "d": [], "t": []}], "preferred_name": "Acinar development of breast", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0019545", "l": "arginine catabolic process to succinate", "d": ["The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate."], "t": []}, {"i": "UMLS:C1156709", "l": "arginine catabolic process to succinate", "d": [], "t": []}], "preferred_name": "arginine catabolic process to succinate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "77.385985069337295", "identifiers": [{"i": "GO:0006505", "l": "GPI anchor metabolic process", "d": ["The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. 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This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch."], "t": []}, {"i": "UMLS:C2245267", "l": "transcriptional attenuation by ribosome", "d": [], "t": []}], "preferred_name": "transcriptional attenuation by ribosome", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C3271203", "d": [], "t": []}], "preferred_name": "", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "95.435381742291767", "identifiers": [{"i": "GO:0051597", "l": "response to methylmercury", "d": ["Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus."], "t": []}, {"i": "UMLS:C1657130", "l": "response to methylmercury", "d": [], "t": []}], "preferred_name": "response to methylmercury", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "88.200632973717077", "identifiers": [{"i": "GO:0071918", "l": "urea transmembrane transport", "d": ["The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore."], "t": []}, {"i": "UMLS:C3156130", "l": "urea transmembrane transport", "d": [], "t": []}], "preferred_name": "urea transmembrane transport", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "87.185496466908774", "identifiers": [{"i": "GO:0051012", "l": "microtubule sliding", "d": ["The movement of one microtubule along another microtubule."], "t": []}, {"i": "UMLS:C1523037", "l": "microtubule sliding", "d": [], "t": []}], "preferred_name": "microtubule sliding", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C3544859", "l": "activation of macromitophagy", "d": [], "t": []}], "preferred_name": "activation of macromitophagy", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C2259804", "l": "inhibition by symbiont of host T-cell mediated immune response", "d": [], "t": []}], "preferred_name": "inhibition by symbiont of host T-cell mediated immune response", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C3893850", "l": "positive regulation of protein localization to cell tip", "d": [], "t": []}], "preferred_name": "positive regulation of protein localization to cell tip", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C4234833", "l": "inhibition of membrane depolarization", "d": [], "t": []}], "preferred_name": "inhibition of membrane depolarization", "taxa": []} 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"l": "nonadec-1-ene biosynthetic process", "d": [], "t": []}], "preferred_name": "nonadec-1-ene biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C5887021", "l": "inhibition of transcription from RNA polymerase II promoter", "d": [], "t": []}], "preferred_name": "inhibition of transcription from RNA polymerase II promoter", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "76.974266503700335", "identifiers": [{"i": "GO:0016126", "l": "sterol biosynthetic process", "d": ["The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule."], "t": []}, {"i": "UMLS:C1156542", "l": "Sterol Biosynthesis Pathway", "d": [], "t": []}], "preferred_name": "sterol biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0032828", "l": "positive regulation of natural killer cell 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Leading strand elongation proceeds in the same direction as the replication fork."], "t": []}, {"i": "UMLS:C1155656", "l": "leading strand elongation", "d": [], "t": []}], "preferred_name": "leading strand elongation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C1160178", "l": "sporocarp development", "d": [], "t": []}], "preferred_name": "sporocarp development", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C1827292", "l": "Abnormal frequency of defecation", "d": [], "t": []}], "preferred_name": "Abnormal frequency of defecation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C1752436", "l": "NK cell mediated cytolysis", "d": [], "t": []}], "preferred_name": "NK cell mediated cytolysis", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C5450806", "l": "positive regulation of interferon-gamma biosynthetic process", "d": [], "t": []}], "preferred_name": "positive regulation of interferon-gamma biosynthetic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C2370982", "l": "Speed of speech", "d": [], "t": []}], "preferred_name": "Speed of speech", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "75.54482030309893", "identifiers": [{"i": "GO:0033262", "l": "regulation of nuclear cell cycle DNA replication", "d": ["Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle."], "t": []}], "preferred_name": "regulation of nuclear cell cycle DNA replication", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "92.76525123142531", "identifiers": [{"i": "GO:0044733", "l": "envenomation resulting in modulation of acid-sensing ion channel activity in another organism", "d": ["A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism."], "t": []}], "preferred_name": "envenomation resulting in modulation of acid-sensing ion channel activity in another organism", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "30.533586567254265", "identifiers": [{"i": "GO:0051301", "l": "cell division", "d": ["The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells."], "t": []}, {"i": "UMLS:C0007590", "l": "Cell division", "d": [], "t": []}], "preferred_name": "cell division", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C2246140", "l": "activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "d": [], "t": []}], "preferred_name": "activation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "84.836666367283215", "identifiers": [{"i": "GO:1902101", "l": "positive regulation of metaphase/anaphase transition of cell cycle", "d": ["Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle."], "t": []}], "preferred_name": "positive regulation of metaphase/anaphase transition of cell cycle", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1900522", "l": "negative regulation of response to amylopectin", "d": ["Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin."], "t": []}], "preferred_name": "negative regulation of response to amylopectin", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0031388", "l": "organic acid phosphorylation", "d": ["The process of introducing one or more phosphate groups into an organic acid."], "t": []}, {"i": "UMLS:C1622047", "l": "organic acid phosphorylation", "d": [], "t": []}], "preferred_name": "organic acid phosphorylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C0232625", "l": "Intestino-intestinal inhibitory reflex", "d": [], "t": []}], "preferred_name": "Intestino-intestinal inhibitory reflex", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "90.87076348458352", "identifiers": [{"i": "GO:0010405", "l": "arabinogalactan protein metabolic process", "d": ["The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures."], "t": []}, {"i": "UMLS:C2265535", "l": "arabinogalactan protein metabolic process", "d": [], "t": []}], "preferred_name": "arabinogalactan protein metabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0016031", "l": "tRNA import into mitochondrion", "d": ["The process in which a tRNA is transported from the cytosol into the mitochondrial matrix."], "t": []}], "preferred_name": "tRNA import into mitochondrion", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "85.53050246285062", "identifiers": [{"i": "GO:1905047", "l": "mitotic spindle pole body organization", "d": ["A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body."], "t": []}, {"i": "UMLS:C4235507", "l": "mitotic spindle pole body organization", "d": [], "t": []}], "preferred_name": "mitotic spindle pole body organization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C3158464", "d": [], "t": []}], "preferred_name": "", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C5165769", "l": "Glucose tolerance | Serum or Plasma | Chemistry - challenge", "d": [], "t": []}], "preferred_name": "Glucose tolerance | Serum or Plasma | Chemistry - challenge", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1904874", "l": "positive regulation of telomerase RNA localization to Cajal body", "d": ["Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body."], "t": []}], "preferred_name": "positive regulation of telomerase RNA localization to Cajal body", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C2265389", "l": "stimulation of trichoblast fate", "d": [], "t": []}], "preferred_name": "stimulation of trichoblast fate", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0106040", "l": "regulation of GABA-A receptor activity", "d": ["Any process that modulates the frequency, rate or extent of GABA-A receptor activity."], "t": []}, {"i": "UMLS:C4690668", "l": "regulation of GABA-A receptor activity", "d": [], "t": []}], "preferred_name": "regulation of GABA-A receptor activity", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C2613366", "l": "negative regulation of gene expression via chromosomal CpG island methylation", "d": [], "t": []}], "preferred_name": "negative regulation of gene expression via chromosomal CpG island methylation", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "86.306145226875287", "identifiers": [{"i": "GO:0045734", "l": "regulation of acetate catabolic process", "d": ["Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid."], "t": []}, {"i": "UMLS:C1158133", "l": "regulation of acetate catabolic process", "d": [], "t": []}], "preferred_name": "regulation of acetate catabolic process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:1902237", "l": "positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "d": ["Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway."], "t": []}], "preferred_name": "positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": null, "identifiers": [{"i": "UMLS:C0234410", "l": "Physiologic disinhibition", "d": [], "t": []}], "preferred_name": "Physiologic disinhibition", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0051290", "l": "protein heterotetramerization", "d": ["The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical."], "t": []}, {"i": "UMLS:C1655260", "l": "protein heterotetramerization", "d": [], "t": []}], "preferred_name": "protein heterotetramerization", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0039527", "l": "symbiont-mediated suppression of host TRAF-mediated signal transduction", "d": ["A process in which a symbiont interferes with, inhibits or disrupts a TRAF-mediated signal transduction pathway in the host organism. 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A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence."], "t": []}, {"i": "UMLS:C0031845", "l": "Physiological Processes", "d": [], "t": []}], "preferred_name": "biological process", "taxa": []} {"type": "biolink:BiologicalProcess", "ic": "100", "identifiers": [{"i": "GO:0060577", "l": "pulmonary vein morphogenesis", "d": ["The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. 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