name: Direct recruitment of PI3K to p-KIT (Sus scrofa)


name: MTHFD2, D2L oxidise 5,10-methylene-THF to 5,10-methenyl-THF (Xenopus tropicalis)


name: 2-oxopentanoate + L-kynurenine => L-2-aminopentanoate + kynurenate + H2O


name: Association of GABA B receptor with G protein beta-gamma subunits (Drosophila melanogaster)


name: an aliphatic amine + A + H2O => an aldehyde + AH2 + NH4(+)


name: THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)


name: RAB9 binds RHOBTB3, bringing late endosome-derived vesicles to the TGN (Mus musculus)


name: RHOC activates endoplasmic reticulum effectors (Sus scrofa)


name: hydrogencarbonate(out) + Na(+)(out) => hydrogencarbonate(in) + Na(+)(in)


name: CYP8B1 12-hydroxylates 4CHOL7aOLONE (Canis familiaris)


name: C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-tyrosine + ATP <=> C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-tyrosyl-[tubulin] + ADP + phosphate + H(+)


name: S-Farn-Me KRAS4B binds calmodulin (Homo sapiens)


name: TP53 stimulates PCBP4 expression (Homo sapiens)


name: ZNRF3 autoubiquitinates to promote its internalization (Xenopus tropicalis)


name: isoorientin + UDP + H(+) => luteolin + UDP-alpha-D-glucose


name: MPST transfers sulfur from sulfanegen to HCN to form HSCN (Canis familiaris)


name: GRK2 sequesters activated Gq (Rattus norvegicus)


name: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal + (11R)-carlactone


name: ATP12A:ATP4B exchanges K+ for H+ (Rattus norvegicus)


name: a penicillin + H2O <=> 6-aminopenicillanate + a carboxylate


name: Active ARF recruits coatomer (Saccharomyces cerevisiae)


name: Mitochondrial NUDT9 hydrolyses ADP-ribose to R5P and AMP (Rattus norvegicus)


name: an N-(2-hydroxyacyl)-beta-D-galactosyl-sphinganine + UDP + H(+) => an N-(2-hydroxyacyl)-sphinganine + UDP-alpha-D-galactose


name: RND3 binds GTP (Schizosaccharomyces pombe)


name: 3-methylbenzaldehyde + NAD(+) + H2O <=> 3-methylbenzoate + NADH + 2 H(+)


name: 2-hydroxy-4-methylpentanoate + O2 <=> 4-methyl-2-oxopentanoate + H2O2


name: kynurenine + O2 + NADPH + H+ => 3-hydroxykynurenine + NADP+ + H2O (Dictyostelium discoideum)


name: N-hexadecanoylethanolamine + H2O = ethanolamine + hexadecanoate


name: p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Canis familiaris)


name: 4-chloro-L-lysine + AH2 + O2 = L-2-amino-4-chloropent-4-enoate + formaldehyde + A + NH4(+) + H2O


name: SUMOylation of CREBBP with SUMO1 (Homo sapiens)


name: (Z,S)-cinerolone + (1R,3R)-pyrethroyl-CoA => cinerin II + CoA


name: (8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 A + 2 H2O => (8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 AH2


name: DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)


name: L-saccharopine + O2 + H2O => (S)-2-amino-6-oxohexanoate + L-glutamate + H2O2


name: fumagillol + NADP(+) => 5-dehydrofumagillol + NADPH + H(+)


name: The distal appendage proteins recruit TTBK2 (Mus musculus)


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Danio rerio)


name: bis(myo-inositol) 1,3'-phosphate + 2 GDP-alpha-D-mannose = 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + 2 GDP + 2 H(+)


name: pro-SFTPC translocates from ER membrane to multivesicle body (Mus musculus)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Rattus norvegicus)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Saccharomyces cerevisiae)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O


name: activation of hypoxia-inducible factor-1alpha signaling pathway


name: The retrograde IFT train dissociates (Sus scrofa)


name: JAK2-activated MAPKs phosphorylate YBX1 (Gallus gallus)


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Gallus gallus)


name: L-threonine(out) + H(+)(out) => L-threonine(in) + H(+)(in)


name: biotin + ATP + H(+) => biotinyl-5'-AMP + diphosphate


name: RAC1 GDIs block activation of RAC1 (Caenorhabditis elegans)


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Sus scrofa)


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Schizosaccharomyces pombe)


name: 2 L-tyrosyl-tRNA(Tyr) <=> cyclo(L-tyrosyl-L-tyrosyl) + 2 tRNA(Tyr)


name: KSPG is secreted from the cell (Xenopus tropicalis)


name: LIN7, CASK and APBA1 bind (Xenopus tropicalis)


name: 2xTRAP hydrolyzes FMN to RIB (Sus scrofa)


name: FUT2 transfers Fuc to LeX to form LeY (Xenopus tropicalis)


name: N-acetyl-L-cysteine + oxaloacetate + NAD(+) + H2O => N-acetyl-S-(2-succino)-L-cysteine + NADH + O2 + H(+)


name: but-3-ynal + NAD(+) + H2O => 3-butynoate + NADH + 2 H(+)


name: P4HB:4-Hyp collagen propeptides dissociates (Bos taurus)


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Rattus norvegicus)


name: activation of alkane biosynthetic process


name: Initial activation of proMMP13 by plasmin and trypsin (Xenopus tropicalis)


name: CARD8 binds CASP9(1-416) (Canis familiaris)


name: arsenate + AH2 + H(+) => arsenite + A + H2O


name: CANX dissociates from IL12A:EBI3 (Rattus norvegicus)


name: C1-Inh binds and inactivates C1r, C1s (Gallus gallus)


name: activation of nickel superoxide dismutase activity


name: 4-methylsulfanyl-2-oxobutanoate + L-kynurenine => kynurenate + L-methionine + H2O


name: L-tryptophan + dimethylallyl diphosphate = 7-(3-methylbut-2-enyl)-L-tryptophan + diphosphate


name: N-terminal L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-methionine = N-terminal N,N,N-trimethyl-L-seryl-L-prolyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: (13S)-hydroperoxy-(9Z,11E)-octadecadienoate + 2 glutathione <=> (13S)-hydroxy-(9Z,11E)-octadecadienoate + glutathione disulfide + H2O


name: 8,12-diethyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-methionine = 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-adenosyl-L-homocysteine + H(+)


name: (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside(in) + ATP + H2O => (4Z,15Z)-bilirubin IXalpha C8-beta-D-glucuronoside(out) + ADP + phosphate + H(+)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Sus scrofa)


name: 3-[(1-carboxyvinyl)-oxy]benzoate + S-adenosyl-L-methionine + H2O = 6-amino-6-deoxyfutalosine + hydrogencarbonate + L-methionine + H(+)


name: De novo formation of eIF2:GTP (Gallus gallus)


name: 2-acyl LPG is acylated to PG by LPGAT (Caenorhabditis elegans)


name: DLAT trimer transfers acetyl to CoA (Xenopus tropicalis)


name: eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity


name: gibberellin A25 + 3 succinate + 3 CO2 + H2O + H(+) => gibberellin A12 + 3 2-oxoglutarate + 3 O2


name: LGI1 binds ADAM22 and ADAM23 (Canis familiaris)


name: cholesterol + NADPH + O2 + H(+) <=> 25-hydroxycholesterol + NADP(+) + H2O


name: UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-glutamate => UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-oxoglutarate


name: 3-phenyllactate + NAD(+) => 3-phenylpyruvate + NADH + H(+)


name: beta-alanyl-tryptamine + AMP + diphosphate + H(+) => tryptamine + beta-alanine + ATP


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate => an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)


name: Covalent tyrosine kinase inhibitors bind and inactivate EGFR kinase domain mutant dimers resistant to non-covalent tyrosine kinase inhibitors (Homo sapiens)


name: NR3C1 ligands bind NR3C1 (in the HSP90 chaperone complex) (Canis familiaris)


name: Dephosphorylation of p107 (RBL1) by PP2A (Dictyostelium discoideum)


name: transmembrane receptor protein tyrosine kinase adaptor activity


name: B4GALT5/6 transfer Gal to GlcCer (Rattus norvegicus)


name: (S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)


name: FASL:FAS Receptor Trimer:FADD complex binds procaspase-10 (Sus scrofa)


name: 2'-dehydrokanamycin A + NADPH + H(+) <=> kanamycin A + NADP(+)


name: EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Homo sapiens)


name: N(5)-(L-ornithyl)-[N(5)-(L-ornithyl)]n-1 + n AMP + n diphosphate + n H(+) => n L-ornithine + n ATP + H2O


name: SLCO2A1 transports PGT substrates from extracellular region to cytosol (Canis familiaris)


name: a methylated nucleobase within DNA + 2-oxoglutarate + O2 => a nucleobase within DNA + formaldehyde + succinate + CO2


name: CDKN1B is phosphorylated in response to estrogen (Rattus norvegicus)


name: a macrocyclic archaeaol phospholipid + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+) => a 2,3-di-O-phytanyl-sn-glycerophospholipid + AH2 + 2 S-adenosyl-L-methionine


name: Light stimulates opsin receptors (Danio rerio)


name: CDK2 phosphorylates RBBP8 (Mus musculus)


name: lutein + O2 <=> (3R,6R)-hydroxy-alpha-ionone + (3R)-3-hydroxy-10'-apo-beta-carotenal


name: Inactivation of R-Ras by Sema4D-Plexin-B1 GAP activity (Canis familiaris)


name: negative regulation of penicillin biosynthetic process


name: 2 (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside = bilirubin IXalpha bis-beta-D-glucuronoside + (4Z,15Z)-bilirubin IXalpha


name: Increased Smooth Muscle Brain Derived Neurotropic Activity


name: Abortive initiation after formation of the first phosphodiester bond (Caenorhabditis elegans)


name: ATF5 and HSF1 trimer bind the HSPA9 gene (Homo sapiens)


name: Formation of the 43S pre-initiation complex (Saccharomyces cerevisiae)


name: Cytosolic CMs translocate to extracellular region (Mus musculus)


name: SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Bos taurus)


name: ERK1/2/5 activate RSK1/2/3 (Xenopus tropicalis)


name: NRPE dissociates to atRAL and PE (Homo sapiens)


name: (2R,3R)-2,3-dihydroxy-3-methylpentanoate => (S)-3-methyl-2-oxopentanoate + H2O


name: PSAP(195-273) dimer binds PE (Bos taurus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + an N-acylsphing-4-enine = an N-acylsphing-4-enine 1-phosphoethanolamine + 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol


name: medium-chain fatty acid omega-hydroxylase activity


name: a ganglioside GA2 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GM2 (d18:1(4E)) + CMP + H(+)


name: isopentenyl diphosphate + ADP => isopentenyl phosphate + ATP


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Drosophila melanogaster)


name: G alpha (z):RGS complex dissociates to give inactive G alpha (z) (Schizosaccharomyces pombe)


name: Phosphorylation of CARMA1 by PKC-theta (Mus musculus)


name: inhibition of Rho protein signal transduction


name: 3-(methylsulfanyl)acryloyl-CoA + H2O <=> 3-hydroxy-3-(methylsulfanyl)propanoyl-CoA


name: protein phosphatase type 1 activator activity


name: RCHY1 monoubiquitinates POLH (Xenopus tropicalis)


name: a quinone + D-glucose => D-glucono-1,5-lactone + a quinol


name: a 2-oxocarboxylate + L-asparagine <=> 2-oxosuccinamate + an L-alpha-amino acid


name: EXT1:EXT2 transfer GlcNAc to the heparan chain (Sus scrofa)


name: N-(dodecanoyl)-sphinganine + H2O = dodecanoate + sphinganine


name: negative regulation of DNA topoisomerase II


name: 1,3-di-(9Z-octadecenoyl)-glycerol + H2O => 3-(9Z-octadecenoyl)-sn-glycerol + (9Z)-octadecenoate + H(+)


name: PI3K catalyses the phosphorylation of PIP2 to PIP3 (Canis familiaris)


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Homo sapiens)


name: 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 (Rattus norvegicus)


name: SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) (Drosophila melanogaster)


name: Cleavage of NODAL proprotein (Homo sapiens)


name: Phosphorylated STAT1, STAT3 form dimers (Sus scrofa)


name: dodecanoyl-CoA + NAD(+) => (2E)-dodecenoyl-CoA + NADH + H(+)


name: Cytosolic CMs translocate to extracellular region (Homo sapiens)


name: (3R)-hydroxyoctadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O


name: 2xPPCS ligates PPanK with Cys (Rattus norvegicus)


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Rattus norvegicus)


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Caenorhabditis elegans)


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Sus scrofa)


name: hexacosanoyl-CoA + glycine <=> N-hexacosanoylglycine + CoA + H(+)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Drosophila melanogaster)


name: positive regulation of TNF-alpha-mediated signaling pathway


name: (2E)-octadecenoyl-[ACP] + NADPH + H(+) <=> octadecanoyl-[ACP] + NADP(+)


name: PI(4,5)P2 is dephosphorylated to PI4P by OCRL/INPP5E at the Golgi membrane (Rattus norvegicus)


name: TGFBR3 translocation to plasma membrane (Homo sapiens)


name: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+)


name: Dissociation of insulin from insulin receptor (Rattus norvegicus)


name: 3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP + H(+) => 3-O-(beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-galactose


name: UGT1A3 lactonizes ATV to ATVL (Gallus gallus)


name: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UMP => UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + di-trans,octa-cis-undecaprenyl phosphate


name: (S)-ureidoglycolate => urea + glyoxylate


name: IRAK2 is phosphorylated downstream of IRAK4 following IL1 receptor activation (Bos taurus)


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Xenopus tropicalis)


name: DLCL is acylated to MLCL by LCLAT1 (ER) (Canis familiaris)


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Bos taurus)


name: androst-4-ene-3,17-dione + NADPH + H(+) = 5alpha-androstan-3,17-dione + NADP(+)


name: 2-dehydro-3-deoxy-D-gluconate + H2O => D-gluconate


name: a ganglioside GA2 (d18:1(4E)) + H2O => N-acetyl-beta-D-galactosamine + a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E))


name: JMJD1C demethylates H3K9 mono- and di-methylation (Gallus gallus)


name: TXNIP binds reduced thioredoxin (Bos taurus)


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Canis familiaris)


name: Hydroperoxy reductase reduces 7(S),14(S)-diHp-DHA to 7-epi-MaR1 (Homo sapiens)


name: BPGM dimer isomerises 1,3BPG to 2,3BPG (Dictyostelium discoideum)


name: a 2,3-diacyl-sn-glycerol + an acyl-CoA <=> a triacyl-sn-glycerol + CoA


name: 5,7-dibromo-L-tryptophan + O2 => 5,7-dibromo-indole-3-carbonitrile + glycolate + H2O + H(+)


name: estrone + reduced [NADPH--hemoprotein reductase] + O2 <=> 2-hydroxyestrone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: ACVRL1 binds BMP9,BMP10 (Drosophila melanogaster)


name: octadecanoyl-[ACP] + NADP(+) => (2E)-octadecenoyl-[ACP] + NADPH + H(+)


name: hexadecanoyl-CoA + 2-oxoglutarate + O2 <=> 2-hydroxyhexadecanoyl-CoA + succinate + CO2


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP <=> 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-phosphate) + ADP + H(+)


name: (Z)-dehydrocyclopeptine + 2-oxoglutarate + O2 => (-)-cyclopenine + succinate + CO2


name: S1P hydrolyzes SREBP1A,1C,2 (Bos taurus)


name: beta-alanyl-tryptamine + holo-[peptidyl-carrier protein] + H(+) => beta-alanyl-[peptidyl-carrier protein] + tryptamine


name: pentanoate + ATP + CoA = pentanoyl-CoA + AMP + diphosphate


name: [aequorin]--dioxetanone = excited state-[aequorin] + CO2


name: L-glutamyl-L-arginyl-glycyl-L-methionyl-L-threonine(in) + Na(+)(in) => L-glutamyl-L-arginyl-glycyl-L-methionyl-L-threonine(out) + Na(+)(out)


name: 1-O-alkyl-2-acyl-sn-glycerol + ATP = 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: Release of p-STAT2:p-STAT1 dimer (Homo sapiens)


name: DKK promotes clathrin-dependent internalization of LRP6 (Rattus norvegicus)


name: Fgr may phosphorylate p38 MAPK (Sus scrofa)


name: KDM5A-D demethylate Me3K5-histone H3 (Homo sapiens)


name: Expression of Stress-70 protein, mitochondrial (Homo sapiens)


name: 3-methylbutanoyl-CoA + AMP + diphosphate => 3-methylbutanoate + ATP + CoA


name: Phosphorylation of Cdh1 by Cyclin B1:Cdc2 (Xenopus tropicalis)


name: FEN1 cleaves displaced ssDNA flaps during MMEJ (Drosophila melanogaster)


name: BESTs transport cytosolic Cl- to extracellular region (Rattus norvegicus)


name: chlorogenate + D-glucarate => 2-O-caffeoylglucarate + L-quinate


name: an N-(34-hydroxytetratriacontenoyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol <=> an N-(34-(9Z,12Z-octadecadienoyloxy)-tetratriacontenoyl)-sphing-4-enine + a diacylglycerol


name: SPTLC complexes transfer acyl-CoA onto serine (Rattus norvegicus)


name: N(6)-methyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-methionine <=> N(6),N(6)-dimethyl-L-lysyl(37)-[histone H3] + S-adenosyl-L-homocysteine + H(+)


name: Defective SLC4A4 does not cotransport Na+ with 3HCO3- (Homo sapiens)


name: Latent TGF-beta-1 is cleaved by FURIN (Sus scrofa)


name: Xaa-L-Pro dipeptide + H2O = an L-alpha-amino acid + L-proline


name: 3-deoxyglucosone + NAD(+) + H2O <=> 2-dehydro-3-deoxy-D-gluconate + NADH + 2 H(+)


name: adenosine + O2 => 5'-dehydroadenosine + H2O2


name: cAMP dissociates PKA, promoting GLI processing (Danio rerio)


name: transmembrane ascorbate ferrireductase activity


name: an R-cob(III)alamin(out) + ATP + H2O => an R-cob(III)alamin(in) + ADP + phosphate + H(+)


name: Auto-ubiquitination of TRAF6 (Mus musculus)


name: PPM1D dephosphorylates RUNX2 (Sus scrofa)


name: SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Sus scrofa)


name: Translocation of cytosolic ERBB4s80 to mitochondrial matrix (Drosophila melanogaster)


name: 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose => 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+)


name: SIRT4 transfers ADPRib to GLUD (Canis familiaris)


name: S-methyl-(E)-thiourocanate + H2O <=> S-methyl-thiohydantoin-5-propanoate


name: Phosphorylation of Cyclin B1 in the CRS domain (Mus musculus)


name: branched-chain 2-keto acid dehydrogenase activity


name: 2-methylfumaryl-CoA + succinate => mesaconate + succinyl-CoA


name: Translocation of PLC-gamma1 to PIP2 (Schizosaccharomyces pombe)


name: APBB1 and MAPK8 bind diphosphorylated H2AFX (Homo sapiens)


name: a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O = N-acetyl-D-galactosamine + L-threonyl-[protein]


name: FUK phosphorylates beta-Fuc to Fuc1P (Caenorhabditis elegans)


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Danio rerio)


name: ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Rattus norvegicus)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Mus musculus)


name: Interaction of Tie2 and Grb14 (Bos taurus)


name: oxidized [electron-transfer flavoprotein] + (9Z)-octadecenoyl-CoA + H(+) = (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: (-)-vetispiradiene + diphosphate => (2E,6E)-farnesyl diphosphate


name: trans-5-O-(4-coumaroyl)-D-quinate + reduced [NADPH--hemoprotein reductase] + O2 = 5-O-[(E)-caffeoyl]-D-quinate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: SPARC binds Collagen type I fibril, hydroxylapatite and Ca2+ (Mus musculus)


name: L-lysine + glyoxylate => 6-amino-2-oxohexanoate + glycine


name: Association of TFAM:mt promoter complex with POLRMT:TFB2M (Rattus norvegicus)


name: 2 reduced [2Fe-2S]-[ferredoxin] + Na(+)(in) + NAD(+) + H(+) => 2 oxidized [2Fe-2S]-[ferredoxin] + Na(+)(out) + NADH


name: acetoacetate + fumarate + H(+) => 4-fumarylacetoacetate + H2O


name: p-VAV family:PIP3 binds RAC1:GDP (Mus musculus)


name: GGCX gamma-carboxylates F7(21-466) (pro-factor VII) (Xenopus tropicalis)


name: cyclohexanone + NADP(+) => cyclohex-2-enone + NADPH + H(+)


name: Activated FGFR1 phosphorylates SHC1 (Caenorhabditis elegans)


name: a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-ribonucleotide in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleoside)-(2'-O-methyl-ribonucleotide) in mRNA + S-adenosyl-L-homocysteine + H(+)


name: 2 a menaquinone + 2 H2O(in) + n H(+)(out) => 2 a menaquinol + O2 + n H(+)(in)


name: 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphocholine + H2O => 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + choline + H(+)


name: dUMP(out) + CTP(in) => dUMP(in) + CTP(out)


name: NEK9 phosphorylates NEK6/NEK7 (Caenorhabditis elegans)


name: Vinyl chloride is oxidized to 2-Chloroethylene oxide (Homo sapiens)


name: SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Canis familiaris)


name: BCDX2 complex formation (Canis familiaris)


name: FOXO1,FOXO3,(FOXO4) bind FASLG gene promoter (Homo sapiens)


name: glutamine + H2O => glutamate + NH4+ (GLS) (Bos taurus)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Caenorhabditis elegans)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Drosophila melanogaster)


name: Activated MET binds GAB1 and GRB2 (Homo sapiens)


name: 1,2-dihexanoyl-sn-glycerol + (9Z)-octadecenoyl-CoA => 1,2-dihexanoyl-3-(9Z-octadecenoyl)-sn-glycerol + CoA


name: neamine + 5-phospho-alpha-D-ribose 1-diphosphate => 5''-phosphoribostamycin + diphosphate


name: ULK1 phosphorylates RIPK1 at S357 (Mus musculus)


name: Connexin 62 mediated neuronal gap junction communication (Danio rerio)


name: salicylate + acetate + H(+) => acetylsalicylate + H2O


name: an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O = an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)


name: Phosphorylation of ROBO1 by ABL kinase (Mus musculus)


name: pristanoyl-CoA + H2O <=> 2,6,10,14-tetramethylpentadecanoate + CoA + H(+)


name: N,N-dihydroxy-L-valine + H(+) <=> (E)-2-methylpropanal oxime + CO2 + H2O


name: methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity


name: GOT2 transaminates OA and L-Glu (Mus musculus)


name: maintenance of protein location in ER lumen


name: 7,9,10-trihydroxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + S-adenosyl-L-methionine <=> 9,10-dihydroxy-7-methoxy-3-(2-oxopropyl)-1H-benzo[g]isochromen-1-one + S-adenosyl-L-homocysteine + H(+)


name: REV1-Pol kappa complex formation (Gallus gallus)


name: glycochenodeoxycholate(in) + glutathione(in) + ATP + H2O <=> glycochenodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)


name: S100A8:S100A9 binds Zn2+ (Rattus norvegicus)


name: positive regulation of amyloid fibril formation


name: ASPA deacetylates NAASP to acetate and L-aspartate (Rattus norvegicus)


name: GABAB heterodimeric receptor binds GABA (Gallus gallus)


name: L-glutamyl-tRNA(Glu) + AMP + diphosphate => tRNA(Glu) + L-glutamate + ATP


name: PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Homo sapiens)


name: malonyl-CoA + NADPH + H(+) => 3-oxopropanoate + NADP(+) + CoA


name: HIPK2 phosphorylates RUNX1 and EP300 (Bos taurus)


name: WDR5 binds Me2sR3-replicative histone H3 (Saccharomyces cerevisiae)


name: parthenolide + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (+)-costunolide + reduced [NADPH--hemoprotein reductase] + O2


name: NEDD8 and UBD bind NUB1 and the 26S proteasome (Bos taurus)


name: chlorophyllide b + 2 NADP(+) + 3 H2O => chlorophyllide a + 2 NADPH + 2 O2 + 2 H(+)


name: Reduction of disulphide bonds in MHC II antigens (Danio rerio)


name: histone H3K9 trimethyltransferase activity


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Gallus gallus)


name: N-acetyltryptamine + CoA + H(+) => tryptamine + acetyl-CoA


name: N(tele)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine + H(+) => L-histidyl-[protein] + S-adenosyl-L-methionine


name: inhibition of tyrosine phosphorylation of JAK2 protein


name: PTPS is phosphorylated by cGMP-dependant protein kinase II (Bos taurus)


name: HSF1 trimer translocates to the nucleus (Drosophila melanogaster)


name: PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Canis familiaris)


name: (R)-lactate(in) + (S)-malate(out) => (R)-lactate(out) + (S)-malate(in)


name: Association of procollagen type XVI (Homo sapiens)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Homo sapiens)


name: ORC6 binds KPNA1 or KPNA6 (Rattus norvegicus)


name: VENTX disrupts binding of CTNNB1 (beta-catenin) to TCF4 or LEF1 (Canis familiaris)


name: SOX17 binds the TET2 gene (Homo sapiens)


name: a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] => a thymidine in DNA + S-methyl-L-cysteinyl-[protein]


name: OCT2 mediates tubular secretion of organic cations in the kidney (Danio rerio)


name: Conjugation of SUMO1 to UBA2:SAE1 (Caenorhabditis elegans)


name: Formation of Classical C3 convertase (C4b:C2a complex) (Gallus gallus)


name: Autophosphorylation of insulin receptor (Sus scrofa)


name: TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Mus musculus)


name: 5a,11a-dehydrotetracycline + NADP(+) + H2O => anhydrotetracycline + NADPH + O2 + H(+)


name: a (R)-2-hydroxy fatty acid + O2 => a fatty acid + CO2 + H2O


name: mRNA8 is translated to protein 8 (Homo sapiens)


name: RDH5,RDH11 oxidise 11cROL to 11cRAL (Drosophila melanogaster)


name: inhibition of NF-kappaB transcription factor


name: PKM dephosphorylates PEP to PYR (Rattus norvegicus)


name: 6-deoxocastasterone + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 => castasterone + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> (-)-kolavenyl diphosphate


name: alpha-D-glucose + beta-D-glucose => alpha,alpha-trehalose + H2O


name: adenylate cyclase-inhibiting opioid receptor signaling pathway


name: structural constituent of collagen and cuticulin-based cuticle


name: 1,2-dichloroethane + H2O => 2-chloroethanol + chloride + H(+)


name: N(6)-hexadecanoyl-L-lysyl-[protein] + NAD(+) + H2O <=> 2''-O-hexadecanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: ursodeoxycholate + lithocholoyl-CoA <=> ursodeoxycholoyl-CoA + lithocholate


name: rutinose + (2S)-hesperetin => (2S)-hesperidin + H2O


name: delta-tocopherol + S-adenosyl-L-methionine => beta-tocopherol + S-adenosyl-L-homocysteine + H(+)


name: L-serine transmembrane transporter activity


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Homo sapiens)


name: orsellinaldehyde + A + 3 CO2 + 4 CoA + H2O => 3 malonyl-CoA + acetyl-CoA + AH2 + 3 H(+)


name: D-glyceraldehyde 3-phosphate + pyruvate + H(+) => 1-deoxy-D-xylulose 5-phosphate + CO2


name: UGT1A3 lactonizes 4-OH-ATV to 4-OH-ATVL (Rattus norvegicus)


name: Cdc45 associates with the pre-replicative complex at the origin (Saccharomyces cerevisiae)


name: p25-bound CDK5 phosphorylates CDC25B (Homo sapiens)


name: D-Arginine and D-Ornithine Metabolism Pathway


name: SHPRH binds monoUb-K164-PCNA, RAD6:RAD18, UBE2V2:Ub:UBE2N (Canis familiaris)


name: AKR1B1 reduces Glc to D-sorbitol (Mus musculus)


name: cytidine(49) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(49) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)


name: taurine(in) + H(+)(in) <=> taurine(out) + H(+)(out)


name: octadecanoyl-CoA + cholesterol = cholesteryl octadecanoate + CoA


name: GNAL exchanges GDP for GTP in odorant:Olfactory Receptor:GNAL:GDP:GNB1:GNG13 (Homo sapiens)


name: Formation of the Cleavage and Polyadenylation Complex (Rattus norvegicus)


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Xenopus tropicalis)


name: PE is converted to PS by PTDSS2 (Xenopus tropicalis)


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Drosophila melanogaster)


name: inhibition of protein phosphatase type 2B activity


name: regulation of cytochrome oxidase activity


name: 3-oxo-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADPH + H(+) <=> (3R)-hydroxy-(10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+)


name: p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Bos taurus)


name: 1,2-dioctanoyl-sn-glycero-3-diphosphate + H2O <=> 1,2-dioctanoyl-sn-glycero-3-phosphate + phosphate + H(+)


name: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O => a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)


name: Activation of Rap1 by cytosolic GEFs (Rattus norvegicus)


name: TP53 family members stimulate BAX transcription (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H2O = a 1-acyl-sn-glycero-3-phospho-L-serine + a fatty acid + H(+)


name: oxalate(in) + formate(out) => oxalate(out) + formate(in)


name: G-protein alpha subunit is inactivated (Caenorhabditis elegans)


name: Activated FGFR4:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)


name: pentanoate + ATP + NADPH + H(+) = pentanal + AMP + diphosphate + NADP(+)


name: SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Canis familiaris)


name: a sn-glycero-3-phosphodiester + H2O <=> an alcohol + sn-glycerol 3-phosphate + H(+)


name: mycobilin a + Fe(2+) + 3 A + 3 H2O => heme b + 3 AH2 + 3 O2 + 2 H(+)


name: SPZ dimer bound TL dimerises at the plasma membrane (Drosophila melanogaster)


name: beta-nicotinamide D-ribonucleotide + diphosphate => 5-phospho-alpha-D-ribose 1-diphosphate + nicotinamide + H(+)


name: positive regulation of maltohexaose transport


name: pseudaminate + CTP = CMP-pseudaminate + diphosphate


name: CYP2F1 dehydrogenates 3-methylindole (Sus scrofa)


name: 2 (E)-4-coumaroyl-CoA + spermidine <=> N(1),N(8)-bis(coumaroyl)-spermidine + 2 CoA + 2 H(+)


name: EP1 subtype prostaglandin E2 receptor binding


name: PP2A-B56 dephosphorylates centromeric cohesin (Rattus norvegicus)


name: E-cadherin degradation by ADAM10, ADAM15 (Homo sapiens)


name: acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity


name: common acute lymphoblastic leukemia antigen activity


name: 3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine <=> 3',4,7-trihydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: Cargo Recognition And Sorting (Bos taurus)


name: (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) <=> (2S)-2-acetolactate + NADPH + H(+)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + an acyl-CoA <=> 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + CoA


name: ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG (Rattus norvegicus)


name: oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor


name: Raf dimer inhibitors bind RAF heterodimers (Bos taurus)


name: positive regulation of phosphatidylserine biosynthetic process


name: chorismate + H2O = (3R,4R)-3,4-dihydroxy-3,4-dihydrobenzoate + pyruvate


name: Integrins alpha3beta1, alpha6beta4 bind laminin-332, 511, 521, (211, 221) (Mus musculus)


name: HTR1A binds HTR1A agonists (Danio rerio)


name: (+)-minovincinine + acetyl-CoA <=> (+)-echitovenine + CoA


name: activation of deadenylylation-independent decapping


name: activation of long-term synaptic potentiation


name: 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA


name: N,N-dimethyl-4-nitrosoaniline + a primary alcohol = 4-(hydroxylamino)-N,N-dimethylaniline + an aldehyde


name: HEXB cleaves the terminal GalNAc from DS (Drosophila melanogaster)


name: Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Drosophila melanogaster)


name: Binding of ATR-ATRIP to the RPA-ssDNA complex (Drosophila melanogaster)


name: asc-DeltaC9-CoA + H2O2 => asc-C9-CoA + O2


name: AKT phosphorylates FOXO transcription factors (Mus musculus)


name: fumarate + H2O <=> malate (Gallus gallus)


name: a 5-methyl-2'-deoxycytidine in DNA + L-ascorbate + O2 => a (8S,9R)-5-glyceryl-2'-deoxycytidine in DNA + glyoxylate + CO2


name: (3R)-hydroxy-(13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA + NADP(+) => (13Z,16Z,19Z,22Z)-3-oxooctacosatetraenoyl-CoA + NADPH + H(+)


name: 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 = eupatolide + oxidized [NADPH--hemoprotein reductase] + 2 H2O


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)


name: L-tyrosine + S-adenosyl-L-methionine + NADPH <=> 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + NADP(+)


name: CES1,CES2 hydrolyze ASA- to ST (Xenopus tropicalis)


name: Phosphorylation of HSF1 at Ser326 induces transactivation (Caenorhabditis elegans)


name: RNA(n) + a ribonucleoside 5'-diphosphate => RNA(n+1) + phosphate


name: NSL acetylates histone H4 (Homo sapiens)


name: OGG1beta translocates to mitochondria (Mus musculus)


name: Phosphorylated MOB1A proteins associate with LATS proteins (Sus scrofa)


name: DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Dictyostelium discoideum)


name: GLI2,3 are degraded by the proteasome (Dictyostelium discoideum)


name: bisanhydrobacterioruberin + 2 H2O => bacterioruberin


name: Defective GNS does not hydrolyse 6-sulfate from GlcNAc6S (Homo sapiens)


name: H2 + 8 oxidized [2Fe-2S]-[ferredoxin] + 2 NH4(+) + 16 ADP + 16 phosphate + 6 H(+) => N2 + 8 reduced [2Fe-2S]-[ferredoxin] + 16 ATP + 16 H2O


name: S-(9Z-hexadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => (9Z)-hexadecenoyl-CoA + H2O


name: DCXR tetramer reduces L-xylulose to xylitol (Drosophila melanogaster)


name: N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-alanine => N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-L-alanine + O2


name: serotonin(in) + n H(+)(out) = serotonin(out) + n H(+)(in)


name: 3-hydroxybutanoyl-CoA + NAD(+) => acetoacetyl-CoA + NADH + H(+)


name: Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A (Drosophila melanogaster)


name: N-(4-carboxy-4-oxobutanoyl)-L-ethylglycylglycine + H2O => N-(2-aminobutanoyl)glycine + 2-oxoglutarate


name: CYP39A1 7-hydroxylates 24OH-CHOL (Mus musculus)


name: Activation of Ca impermeable AMPA receptors (Mus musculus)


name: SEMA4D interacts with Plexin-B1:ErbB2 (Homo sapiens)


name: (24S)-hydroxycholesterol 24-sulfate + 3'-phosphoadenylyl sulfate => (24S)-hydroxycholesterol 3,24-disulfate + adenosine 3',5'-bisphosphate + H(+)


name: activation of DNA replication origin binding


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Bos taurus)


name: Autophosphorylation of LYN kinase (Mus musculus)


name: tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity


name: Calcineurin binds NFATC1,2,3 (Gallus gallus)


name: an acyl phosphate + H2O => a carboxylate + phosphate + H(+)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Bos taurus)


name: (2E)-13-methyltetradecenoyl-CoA + H2O => 3-hydroxyisopentadecanoyl-CoA


name: N-acetyl-alpha-neuraminate => 2-deoxy-2,3-dehydro-N-acetylneuraminate + H2O


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Canis familiaris)


name: prostaglandin A2 + glutathione = prostaglandin A2-S-(S)-glutathione


name: CLEC4D binds mycobacterial trehalose-6,6'-dimycolate (TDM) (Danio rerio)


name: Aquaporins passively transport water into cells (Caenorhabditis elegans)


name: a 1,1-dimethyl-3-phenylurea + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 1-methyl-3-phenylurea + formaldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: steviolmonoside + UDP-alpha-D-glucose <=> steviolbioside + UDP + H(+)


name: 1-(10Z-heptadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + CoA => 1-(10Z-heptadecenoyl)-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA


name: ADP-D-ribose + L-seryl-[protein] => O-(ADP-D-ribosyl)-L-seryl-[protein] + H2O


name: thiamine diphosphate + ADP => thiamine triphosphate + AMP


name: NUBPL transfers 4Fe-4S to NDUFV1, V2 (Dictyostelium discoideum)


name: Initiation of SAHF formation (Rattus norvegicus)


name: testosterone 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate => testosterone 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)


name: Dissociation of IRS-P from insulin receptor (Xenopus tropicalis)


name: EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Mus musculus)


name: DSCAM/DSCAML1 homodimerization (Bos taurus)


name: Ligation of newly synthesized repair patch to incised DNA in TC-NER (Schizosaccharomyces pombe)


name: (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde => prostaglandin H2


name: SCF-FBXL7 ubiquitinates AURKA (Bos taurus)


name: Tenascins C, R, (X, N) bind fibronectin matrix (Bos taurus)


name: diacetyl + NADH + H(+) => (S)-acetoin + NAD(+)


name: glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H(+) => (2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2


name: folate(out) + H(+)(out) => folate(in) + H(+)(in)


name: Autophosphorylation of PDGF alpha/beta receptors (Mus musculus)


name: activation of hepatocyte growth factor receptor signaling pathway


name: BLT receptors can bind LTB4 (Canis familiaris)


name: L-seryl-[peptidyl-carrier protein] + AMP => L-seryl-5'-AMP + holo-[peptidyl-carrier protein]


name: Degradation of ubiquitinated p27/p21 by the 26S proteasome (Drosophila melanogaster)


name: glycine + acetyl-CoA => (2S)-2-amino-3-oxobutanoate + CoA


name: 1'-[1,2-diacyl-sn-glycero-3-phospho]-3'-[2-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine


name: SORD tetramer oxidizes xylitol to D-xylulose (Drosophila melanogaster)


name: ALOX12 oxidises LTA4 to LXA4 (Sus scrofa)


name: N-(32-hydroxydotriacontenoyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol = an N-(32-(9Z,12Z-octadecadienoyloxy)-dotriacontenoyl)-sphing-4-enine + a diacylglycerol


name: kainate receptor binds glutamate (Canis familiaris)


name: SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 (Drosophila melanogaster)


name: type 5 metabotropic glutamate receptor ligand


name: PA is hydrolysed to 1-acyl LPA by PLA2[1] (Bos taurus)


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Gallus gallus)


name: 24,25-dihydrolanosterol + NADP(+) => lanosterol + NADPH + H(+)


name: histone H4K16 deacetylase activity, NAD-dependent


name: NAD-dependent histone H4K16 deacetylase activity


name: 3beta-hydroxyandrost-5-en-17-one + reduced [NADPH--hemoprotein reductase] + O2 <=> 3beta,7alpha-dihydroxyandrost-5-en-17-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (E)-cinnamoyl-CoA + H2O2 + CO2 => benzylmalonyl-CoA + O2 + H(+)


name: NR1H2,3 binds the APOD gene (Homo sapiens)


name: Kinesins move along microtubules consuming ATP (Drosophila melanogaster)


name: respiratory electron transport chain activity


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Homo sapiens)


name: N-terminal L-methionyl-L-aspartyl-[protein] + acetyl-CoA <=> N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein] + CoA + H(+)


name: dioctanoylglycerol + octanoate + H(+) => 1,2,3-trioctanoylglycerol + H2O


name: Necl-2:Nectin 3 trans heterodimer interaction (Danio rerio)


name: Glutamine transport from astrocytes (Sus scrofa)


name: TP53 binds STK11 and NUAK1 (Rattus norvegicus)


name: PDCL releases folded G-beta from TRiC/CCT (Homo sapiens)


name: Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Bos taurus)


name: sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec (Homo sapiens)


name: 26-oxolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 3beta-hydroxy-lanosta-8, 24-dien-26-oate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: Decreased Peripheral Nervous System Nitric Oxide Activity


name: DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid (Homo sapiens)


name: MAD2 converted  to an inhibitory state via interaction with Mad1 (Xenopus tropicalis)


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Sus scrofa)


name: solasodine + UDP-alpha-D-glucose => solasodine 3-beta-D-glucoside + UDP + H(+)


name: FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: SUMOylation of PIAS4 with SUMO1 (Danio rerio)


name: Translocation of PMAIP1 (NOXA) to mitochondria (Sus scrofa)


name: negative regulation of neuronal signal transduction


name: BLT receptors can bind LTB4 (Bos taurus)


name: N-tetradecanoylsphing-4-enine + H2O => tetradecanoate + sphing-4-enine


name: (2E,6E)-farnesyl diphosphate => (+)-alpha-barbatene + diphosphate


name: 2 L-arginine + 3 NADH + 4 O2 + H(+) => 2 L-citrulline + 2 nitric oxide + 3 NAD(+) + 4 H2O


name: L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-methionine => N(6),N(6),N(6)-trimethyl-L-lysyl(36)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: GALNS oligomer hydrolyses sulfate from Gal6S in keratan sulfate (Mus musculus)


name: Displacement of MUTYH glycosylase by APEX1 at the AP site (Sus scrofa)


name: substance P(1-7) + L-Phe-Gly-L-Leu-L-Met-NH2 => substance P + H2O


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+) = 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADPH


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + decanoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-decanoyl-sn-glycerol + CoA


name: glucuronate acceptor + UDP-alpha-D-glucuronate <=> acceptor beta-D-glucuronoside + UDP + H(+)


name: (5Z,8Z,11Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 => 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: L-gulono-1,4-lactone + H2O = L-gulonate + H(+)


name: p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Mus musculus)


name: 20-methylheneicosan-1-ol + 2 NADP(+) + CoA => 20-methylheneicosanoyl-CoA + 2 NADPH + 2 H(+)


name: RFC binding displaces Pol Alpha (Bos taurus)


name: negative regulation of phosphatidylglycerol biosynthetic process


name: Parenchymal atROL translocates to HSCs (Xenopus tropicalis)


name: I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus (Xenopus tropicalis)


name: a 2'-deoxyguanosine in single-stranded DNA + glyoxal + succinate + CO2 => a 1,N(2)-etheno-2'-deoxyguanosine in single-stranded DNA + 2-oxoglutarate + O2 + H2O


name: (8R,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O <=> (8S,9S)-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate


name: taxa-4,11-diene + reduced [NADPH--hemoprotein reductase] + O2 => taxa-4(20),11-dien-5alpha-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: p85 regulatory unit of PI3K binds p-6Y-SYK (Homo sapiens)


name: L-tyrosine + reduced [NADPH--hemoprotein reductase] + O2 = N-hydroxy-L-tyrosine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: CHSY1 transfers GlcA to chondroitin (Drosophila melanogaster)


name: Clathrin internalises EPH:EFN complexes (Caenorhabditis elegans)


name: (2E,6E)-farnesyl diphosphate <=> beta-bisabolene + diphosphate


name: LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Rattus norvegicus)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Bos taurus)


name: CCND1 binds RUNX3 and displaces EP300 (Caenorhabditis elegans)


name: (3R)-hydroxydocosanoyl-CoA + NADP(+) => 3-oxodocosanoyl-CoA + NADPH + H(+)


name: inosine(in) + H(+)(in) => inosine(out) + H(+)(out)


name: (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate + NAD(+) + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NADH + 2 H(+)


name: TP53 stimulates and ZNF420 inhibits TP53AIP1 expression (Homo sapiens)


name: Recruitment of TRAF6 to CBM complex by binding to MALT1 (Mus musculus)


name: TCR binds microbial lipid-based antigen via CD1 (Canis familiaris)


name: mescaline + S-adenosyl-L-methionine <=> N-methylmescaline + S-adenosyl-L-homocysteine + H(+)


name: L-arginine + O2 + H2O => 5-guanidino-2-oxopentanoate + H2O2 + NH4(+)


name: activation of phosphoprotein phosphatase activity


name: beta-D-glucosyl-(1<->1')-N-hexadecanoylsphing-4-enine + 25-substituted-cholesterol => 25-substituted-cholesteryl beta-D-glucoside + N-hexadecanoylsphing-4-enine


name: a ganglioside GD3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GD2 (d18:1(4E)) + UDP + H(+)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Drosophila melanogaster)


name: positive regulation of ATF6 signaling in response to endoplasmic reticulum stress


name: (3R)-hydroxyoctadeca-4,10-dienoyl-[ACP] + 5 A + 8 CO2 + 8 NADP(+) + 9 CoA + 7 H2O => holo-[ACP] + 8 malonyl-CoA + acetyl-CoA + 5 AH2 + 8 NADPH + 16 H(+)


name: LIG1 binds APEX1 and PCNA at SSB (Bos taurus)


name: Transport of the Mature intronless transcript derived mRNA:TAP:Aly/Ref Complex through the NPC (Homo sapiens)


name: Phosphorylation of PLCgamma by PDGFR (Mus musculus)


name: 4-hydroxy-3-(all-trans-octaprenyl)benzoate + H(+) <=> 2-all-trans-octaprenylphenol + CO2


name: Caspase-mediated cleavage of Z0-2 (Canis familiaris)


name: Collagen type XV restin release (Caenorhabditis elegans)


name: Phosphorylation of Cdh1 by Cyclin B1:Cdc2 (Drosophila melanogaster)


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Sus scrofa)


name: Myelin components can interact with p75NTR:NgR:LINGO1 (Canis familiaris)


name: a globoside NORint + UDP-alpha-D-galactose <=> a globoside NOR2 + UDP + H(+)


name: positive regulation of electron transfer activity


name: chloroorienticin B + dTDP-beta-L-vancosamine = chloroeremomycin + dTDP + H(+)


name: histo-blood group B transferase activity


name: 2-oxobutanoate + L-glutamine => 2-oxoglutaramate + (2S)-2-aminobutanoate


name: N-atom dealkylation of caffeine (Mus musculus)


name: ALB binds extracellular heme (Homo sapiens)


name: PTGIR binds PTGIR agonists (Mus musculus)


name: Formation of N-glucuronides (Rattus norvegicus)


name: hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides


name: Internalization of ubiquitinated FLT3 (Sus scrofa)


name: activation of phospholipase C activity by serotonin receptor signaling pathway


name: naphthalene + NADH + O2 + H(+) <=> (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+)


name: regulation of receptor tyrosine kinase autophosphorylation


name: 6-O-adenylylstreptidine + diphosphate => streptidine + ATP


name: beta-hydroxyisobutyrate + NAD+ <=> methylmalonyl semialdehyde + NADH + H+ (Rattus norvegicus)


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Mus musculus)


name: ITP(in) + UTP(out) => ITP(out) + UTP(in)


name: [ribosomal protein S23]-L-proline + 2-oxoglutarate + O2 = [ribosomal protein S23]-trans-3-hydroxy-L-proline + succinate + CO2


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-galactosamine <=> N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: SLC41A1,2 transport Mg2+ from extracellular region to cytosol (Gallus gallus)


name: Recruitment of  RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex (Xenopus tropicalis)


name: beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol = N-dodecanoylsphing-4-enine + cholesteryl 3-beta-D-glucoside


name: Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Xenopus tropicalis)


name: 2,3-dihydroxybenzoate + holo-[ACP] + ATP => 2,3-dihydroxybenzoyl-[ACP] + AMP + diphosphate


name: a steroid 1,3-dione + AH2 => a 1-hydroxy-3-oxo steroid + A


name: docosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 22-hydroxydocosanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: GLI proteins bind CDC73 (Rattus norvegicus)


name: (R)-lactate + NAD(+) = pyruvate + NADH + H(+)


name: Translocation of DFF to the nucleus (Rattus norvegicus)


name: SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Rattus norvegicus)


name: DOLK phosphorylates DCHOL to DOLP (Gallus gallus)


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Saccharomyces cerevisiae)


name: N-hexacosanoylsphinganine + NADPH + O2 + H(+) => N-(2-hydroxyhexacosanoyl)-sphinganine + NADP(+) + H2O


name: NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Bos taurus)


name: androsterone dehydrogenase (A-specific) activity


name: an aromatic primary alcohol + O2 => an aromatic aldehyde + H2O2


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: Phosphorylation of CBL (EGFR:GRB2:CBL) (Gallus gallus)


name: 4-hydroxy-17beta-estradiol + S-adenosyl-L-methionine <=> 4-methoxy-17beta-estradiol + S-adenosyl-L-homocysteine + H(+)


name: queuosine(34) in tRNA + guanine => guanosine(34) in tRNA + queuine


name: glycyldehydrophenylalanine + H2O => 2,3-didehydrophenylalanine + glycine


name: E-selectin binds E-selectin ligand (Xenopus tropicalis)


name: 1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Xenopus tropicalis)


name: AMP + NH4(+) => adenosine 5'-phosphoramidate + H2O


name: 4'''-demalonylsalvianin + malonyl-CoA = salvianin + CoA


name: "pelargonidin 3-O-(6-caffeoylglucoside) 5-O-(6-O-malonylglucoside) 4'''-malonyltransferase"


name: PIAS1,2-1 SUMOylates XRCC4 with SUMO1 (Bos taurus)


name: a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-alpha-D-galactose = a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+)


name: Decreased Striated Muscle Nitric Oxide Activity


name: (2-hydroxyphenyl)acetate + CO2 => 3-phenylpyruvate + O2


name: RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Bos taurus)


name: cyclic nucleotide-regulated small mechanosensitive ion channel


name: 5-formimidoyltetrahydrofolate + L-glutamate <=> N-formimidoyl-L-glutamate + (6S)-5,6,7,8-tetrahydrofolate


name: Activated FGFR3 phosphorylates FRS2 (Bos taurus)


name: hexadecanoate + NADH + 2 H(+) => hexadecanal + NAD(+) + H2O


name: a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + diphosphate => an all-trans-polyprenyl diphosphate + 4-hydroxybenzoate


name: CLCN1/2/KA/KB transport cytosolic Cl- to extracellular region (Homo sapiens)


name: regulation of proteolysis within lysosome


name: IKBKG subunit of IKK complex binds polyubiquinated RIP1 (Homo sapiens)


name: p-EPHB phosphorylates SDC2 (Drosophila melanogaster)


name: gibberellin A4 + succinate + CO2 => gibberellin A9 + 2-oxoglutarate + O2


name: Formation of AT-AC B Complex (Caenorhabditis elegans)


name: L-proline(out) + ATP + H2O <=> L-proline(in) + ADP + phosphate + H(+)


name: (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) = 4-[(E)-2-isocyanoethenyl]phenol + succinate + 2 CO2 + H2O


name: LPAAT3 acylates lysophosphatidylcholine to yield phosphatidylcholine (Rattus norvegicus)


name: 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate => 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate


name: Receptor CCR7 binds CCL19 and 21 ligands (Gallus gallus)


name: cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Mus musculus)


name: (3R)-hydroxyoctanoyl-CoA + NADP(+) = 3-oxooctanoyl-CoA + NADPH + H(+)


name: L-arabinitol + NAD(+) <=> L-ribulose + NADH + H(+)


name: zolasartan + UDP-alpha-D-glucuronate = zolarsartan O-beta-D-glucuronoside + UDP


name: ADP(out) + phosphate(in) + H(+)(out) = ADP(in) + phosphate(out) + H(+)(in)


name: B4GAT1:LARGE transfers Xyl from UDP-Xyl to GlcA-Xyl-GlcA (Danio rerio)


name: Decreased Peripheral Nervous System Glutamate Activity


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)


name: CYPs hydroxylate DHA to 14(R)-HDHA (Caenorhabditis elegans)


name: (2S)-2-isopropylmalate(out) + sulfate(in) => (2S)-2-isopropylmalate(in) + sulfate(out)


name: Molybdenum ion transfer onto molybdopterin (Bos taurus)


name: a monoacyl-sn-glycero-3-phosphocholine + H2O => a monoacylglycerol + phosphocholine + H(+)


name: oxidoreductase activity, acting on other substrates


name: p62 binds ubiquitinated mitochondrial substrates (Canis familiaris)


name: intracellular ligand-gated calcium channel activity


name: MASTL phosphorylates ENSA (Schizosaccharomyces pombe)


name: TCR binds self-lipid-based antigen via CD1 (Rattus norvegicus)


name: cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid


name: phosphocholine + H2O <=> choline + phosphate


name: N-hexacosanoylsphinganine + NADPH + O2 + H(+) = N-(2-hydroxyhexacosanoyl)-sphinganine + NADP(+) + H2O


name: ABCA12 transports lipids from cytosol to extracellular region (Bos taurus)


name: CDC7 gene expression is repressed by the PRC1L4 complex (Homo sapiens)


name: RRAGA,B hydrolyzes GTP (Xenopus tropicalis)


name: a glycerophospholipid + a 1,2-diacylglycerol = a 1-acyl-sn-glycero-3-phospholipid + a triacylglycerol


name: ent-sandaracopimaradien-3beta-ol + reduced [NADPH--hemoprotein reductase] + O2 => oryzalexin E + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O => 2,5,6-triamino-4-hydroxypyrimidine + D-ribose 5-phosphate


name: a sphingoid 1-phosphate + H2O => a sphingoid base + phosphate


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Bos taurus)


name: Increased Cerebral Cortex Serotonin Activity


name: phosphonoacetaldehyde + H2O = acetaldehyde + phosphate + H(+)


name: TPI1 isomerizes GA3P to DHAP (Dictyostelium discoideum)


name: 10R-hydroperoxy-(6Z,8E,12Z)-octadecatrienoate => (6Z,9Z,12Z)-octadecatrienoate + O2


name: Increased Autonomic Nervous System Aspartate Activity


name: malonyl-CoA + S-adenosyl-L-methionine <=> malonyl-CoA methyl ester + S-adenosyl-L-homocysteine


name: phthalate + NADH + 2 H(+) => 2-formylbenzoate + NAD(+) + H2O


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-L-ribitol => 4-O-[1-D-ribitylphospho-(2R)-1-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: mogroside V + UDP + H(+) => siamenoside I + UDP-alpha-D-glucose


name: L-alanyl-L-aspartate + H2O <=> L-aspartate + L-alanine


name: S-(2-aminoethyl)-L-cysteine + NAD(+) + H2O = S-(acetaldehyde)-L-cysteine + NH4(+) + NADH + H(+)


name: MAP2K1 phosphorylates MAPK3 (Danio rerio)


name: UDP-2-acetamido-3-dehydro-2-deoxy-alpha-D-glucopyranose + L-glutamate => UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate


name: The ligand trap binds the ligand BMP2, blocking BMP signalling (Rattus norvegicus)


name: 7,8-dihydromethanopterin + NADPH + H(+) => 5,6,7,8-tetrahydromethanopterin + NADP(+)


name: beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose <=> beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + GDP + H(+)


name: The COG tethering complex interacts with numerous SNAREs at the Golgi membrane (Canis familiaris)


name: an alkanesulfonate + FMNH2 + O2 = an aldehyde + FMN + sulfite + H2O + 2 H(+)


name: a D-hexose + ATP => a D-hexose 6-phosphate + ADP + H(+)


name: L-glutamate + NAD(+) + H2O <=> 2-oxoglutarate + NH4(+) + NADH + H(+)


name: 9-cis-beta-carotene + O2 => 9-cis-10'-apo-beta-carotenal + beta-ionone


name: PYCR2 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Saccharomyces cerevisiae)


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Xenopus tropicalis)


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Saccharomyces cerevisiae)


name: positive regulation of selenocysteine insertion sequence binding


name: beta-himachalene + diphosphate => (2E,6E)-farnesyl diphosphate


name: negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria


name: PI(3,5)P2 transports from the late endosome membrane to the Golgi membrane (Homo sapiens)


name: Formation of RAD52 heptameric ring structure complexes (Gallus gallus)


name: MT-MMPs are sorted to the plasma membrane (Xenopus tropicalis)


name: activation of 17-methylnonadec-1-ene biosynthetic process


name: SMURF2 binds SMAD2 (Drosophila melanogaster)


name: Dissociation of RAS:RAF complex (Gallus gallus)


name: a ubiquinol + 2 H(+)(out) => H2 + a ubiquinone + 2 H(+)(in)


name: 2,5-dichlorocyclohexa-2,5-dien-1,4-diol + NAD(+) <=> 2,5-dichlorohydroquinone + NADH + H(+)


name: N-benzoylglycine(in) + a dicarboxylate(out) => N-benzoylglycine(out) + a dicarboxylate(in)


name: Autophosphorylation of insulin receptor (Gallus gallus)


name: FADH2-C4alpha-hydroperoxide + rifampicin + NADPH = rifampicin hemiaminal + FADH2 + NADP(+) + H2O + H(+)


name: tryptamine + reduced [NADPH--hemoprotein reductase] + O2 => serotonin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (S,S)-drim-8-en-11-yl diphosphate + H2O = (S,S)-drim-8-en-11-yl phosphate + phosphate + H(+)


name: SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Gallus gallus)


name: guaiacol + reduced [NADH--hemoprotein reductase] + O2 = oxidized [NADH--hemoprotein reductase] + catechol + formaldehyde + H2O + H(+)


name: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + NADH + 2 H(+) => 5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NAD(+) + H2O


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Canis familiaris)


name: (13E)-labda-7,13-dien-15-yl diphosphate = labda-7,13(16),14-triene + diphosphate


name: sarcosine + 2 S-adenosyl-L-methionine = glycine betaine + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: a long-chain fatty acid + ATP + H(+) <=> a long-chain fatty acyl-AMP + diphosphate


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Homo sapiens)


name: 1,3,7-trimethylurate + NADH + O2 + H(+) = 1,3,7-trimethyl-5-hydroxyisourate + NAD(+) + H2O


name: a 3'-end 2'-deoxyribonucleotide-DNA + phosphate => a 3'end (2'-deoxyribonucleotide 3'-phosphate)-DNA + H2O


name: (S)-2-amino-6-oxohexanoate => L-1-piperideine-6-carboxylate + H2O + H(+)


name: L-cysteinyl-[peptidyl-carrier protein] + AMP + H(+) => L-cysteinyl-5'-AMP + holo-[peptidyl-carrier protein]


name: Formation of active mTORC1 complex (Gallus gallus)


name: p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Canis familiaris)


name: activation of adenylate cyclase activity by serotonin receptor signalling pathway


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Dictyostelium discoideum)


name: ADRM1:26S proteaseome binds UCHL5 (Caenorhabditis elegans)


name: USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Schizosaccharomyces pombe)


name: glutarate(in) + succinate(out) => glutarate(out) + succinate(in)


name: positive regulation of protein depolymerization


name: uracil + NADH + H(+) => 5,6-dihydrouracil + NAD(+)


name: Formation of Cyclin B:Cdc2 complexes (Gallus gallus)


name: benzoyl-CoA + AMP + H(+) => benzoyl-AMP + CoA


name: all-trans-antheraxanthin + L-ascorbate = all-trans-zeaxanthin + L-dehydroascorbate + H2O


name: an N-(fatty acyl)-L-serine + H2O = L-serine + a fatty acid


name: 5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Rattus norvegicus)


name: YWHAE dimer binds phosphorylated DENND1 proteins (Drosophila melanogaster)


name: PGA2 is isomerised to PGC2 (Homo sapiens)


name: BTK in G alpha (12)-BTK complex is activated (Drosophila melanogaster)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Caenorhabditis elegans)


name: GBF1 recruits ARF:GDP to the ERGIC (Rattus norvegicus)


name: 7beta-hydroxycholesterol(in) + ATP + H2O => 7beta-hydroxycholesterol(out) + ADP + phosphate + H(+)


name: dTDP-alpha-D-glucose + diphosphate => dTTP + alpha-D-glucose 1-phosphate + H(+)


name: TRAF6 oligomer autoubiquitinates (Homo sapiens)


name: cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine <=> 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: deacetoxyvindoline + 2-oxoglutarate + O2 => 4-O-deacetylvindoline + succinate + CO2


name: quercitrin + UDP + H(+) => UDP-beta-L-rhamnose + quercetin


name: N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine


name: D-cellotetraono-1,5-lactone + H2O = D-cellotetraonate + H(+)


name: molybdate(out) + ATP + H2O <=> molybdate(in) + ADP + phosphate + H(+)


name: KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Rattus norvegicus)


name: tetracosanoyl-CoA + hydrogencarbonate + ATP = 2-carboxytetracosanoyl-CoA + ADP + phosphate + H(+)


name: p-Y389,400-RUFY1 binds PI3P (Drosophila melanogaster)


name: (3R)-hydroxy-(15Z)-tetracosenoyl-CoA + NADP(+) => (15Z)-3-oxotetracosenoyl-CoA + NADPH + H(+)


name: holo-[ACP] + acetyl-CoA <=> acetyl-[ACP] + CoA


name: all-trans-zeaxanthin + O2 <=> (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal


name: (R)-lactate(in) + citrate(out) <=> (R)-lactate(out) + citrate(in)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Sus scrofa)


name: GCHFR binds to GCH1 and negatively regulates its activity (Bos taurus)


name: FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Gallus gallus)


name: 2-methyl-L-serine = L-alanine + formaldehyde


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Drosophila melanogaster)


name: Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Homo sapiens)


name: eNoSC deacetylates histone H3 (Rattus norvegicus)


name: SULT1A3,4 dimers sulfate DA to DAOS (Mus musculus)


name: Caspase-8 activates BID by cleavage (Mus musculus)


name: 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde => 7,8-dihydroneopterin


name: (R)-5-methyl-tetronate + o-quinone methide = peniphenone D


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)


name: a 4'-hydroxyisoflavone + S-adenosyl-L-methionine = a 4'-methoxyisoflavone + S-adenosyl-L-homocysteine + H(+)


name: 3-oxopristanoyl-CoA + CoA => 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA


name: DNMT3B:DNMT3L binds chromatin (Homo sapiens)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Gallus gallus)


name: (9Z)-octadecen-1-ol + 2 NADP(+) + CoA => (9Z)-octadecenoyl-CoA + 2 NADPH + 2 H(+)


name: C-ter TLR7 dimer binds HCQ (Canis familiaris)


name: active transmembrane transporter activity


name: AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD (Homo sapiens)


name: C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Mus musculus)


name: Laminin-511 degradation by MMP14 (Homo sapiens)


name: FUT4,5,9,(10,11) transfer Fuc to Type 2 chains to form LeX (Caenorhabditis elegans)


name: Budding of connexon-containing transport vesicles from the Golgi (Sus scrofa)


name: an omega-methyl-long-chain fatty acid + reduced [NADPH--hemoprotein reductase] + O2 => an omega-hydroxy-long-chain fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 5-phospho-alpha-D-ribose 1-diphosphate + ATP => 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate


name: AFG3L2 degrades mitochondrial inner membrane proteins (Sus scrofa)


name: Proteolytic degradation of ubiquitinated-Cdc25A (Rattus norvegicus)


name: (1S)-3-methyl-cyclohexylamine + NADP(+) + H2O = 3-methylcyclohexanone + NH4(+) + NADPH + H(+)


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ATP = [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + ADP


name: "[amino-group carrier protein]-L-glutamate 6-kinase"


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Xenopus tropicalis)


name: D-glucose 6-phosphate + ADP + H(+) => D-glucose + ATP


name: L-lysine + NADP(+) <=> L-1-piperideine-6-carboxylate + NH4(+) + NADPH + 2 H(+)


name: butanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxybutanoyl-CoA + succinate + CO2


name: SGTA binds mislocalized membrane protein (Rattus norvegicus)


name: PETA and CTP are condensed to CDP-ETA by PCY2 (Plasmodium falciparum)


name: cholesteryl (9Z,12Z)-octadecadienoate + CoA => (9Z,12Z)-octadecadienoyl-CoA + cholesterol


name: down regulation of methylenetetrahydrofolate (reduced riboflavin adenine dinucleotide) reductase activity


name: O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H2O <=> L-selenocysteinyl-tRNA(Sec) + 2 phosphate


name: p-IRF7:p-IRF7 translocates to the nucleus (Bos taurus)


name: propanoyl-CoA + NAD(+) => acryloyl-CoA + NADH + H(+)


name: CSF3R binds CSF3 dimer (Canis familiaris)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Xenopus tropicalis)


name: 5 malonyl-CoA + 4 H(+) => 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + 5 CoA + H2O


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: guanine nucleotide transmembrane transporter activity


name: Activated NOD2 oligomerizes (Dictyostelium discoideum)


name: N-terminal N-formyl-L-methionyl-[peptide] + H2O => N-terminal L-methionyl-[peptide] + formate


name: p-STAT3 dimerizes (Dictyostelium discoideum)


name: Pol II elongation complex moves on the template as transcript elongates (Homo sapiens)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Homo sapiens)


name: 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+) => 1,2-di-(9Z-octadecenoyl)-glycerol + H2O


name: PTPN3 binds p-T183,Y185 MAPK12 (Canis familiaris)


name: 6 Fe(II)-[cytochrome c] + nitrite + 8 H(+) => 6 Fe(III)-[cytochrome c] + NH4(+) + 2 H2O


name: acetylcholine + CoA => choline + acetyl-CoA


name: ALOX5 dehydrogenates 4(S)-Hp-17(S)-HDHA to 4S(5)-epoxy-17(S)-HDHA (Xenopus tropicalis)


name: TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Rattus norvegicus)


name: (E)-alk-1-en-1-SO-peroxol = (Z)-alkanethial oxide


name: negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process


name: ALOX15 dehydrogenates 17(S)-Hp-DHA to 16S,17S-epoxy-DHA (Sus scrofa)


name: N-benzyloxycarbonyl-L-leucine + H2O + H(+) => benzyl alcohol + L-leucine + CO2


name: Loading of acetylcholine in synaptic vesicles (Drosophila melanogaster)


name: LIG1 binds POLB at long-patch BER site (Sus scrofa)


name: B3GALT6 transfers Gal to the tetrasaccharide linker (Caenorhabditis elegans)


name: 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 (Dictyostelium discoideum)


name: propionate 3-nitronate + O2 + H2O = 3-oxopropanoate + nitrite + H2O2 + H(+)


name: Phosphorylation of INFAR1 by TYK2 (Gallus gallus)


name: 1-(9Z,12Z-octadecadienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 1-(9Z,12Z,15Z-octadecatrienoyl)-2-acyl-sn-glycero-3-phosphocholine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Homo sapiens)


name: PTPN1 (PTP1B) dephosphorylates tyrosine-24 of ANXA2 (Annexin-2) (Homo sapiens)


name: xanthosine + NH4(+) => guanosine + H2O + H(+)


name: 16alpha-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => progesterone + reduced [NADPH--hemoprotein reductase] + O2


name: (R)-carnitinyl-CoA => crotonobetainyl-CoA + H2O


name: Caspase 3-mediated cleavage of DFF45 (117) (Canis familiaris)


name: spermine(in) + n H(+)(out) <=> spermine(out) + n H(+)(in)


name: SHC1 binds P-ERBB4 isoform dimers (Bos taurus)


name: Transcytosis and dissociation of botE:NTNHA (Homo sapiens)


name: FUT3 transfers L-fucose to Gal1,3GlcNAc (Bos taurus)


name: RELN:VLDLR:DAB1 binds SH3KBP1 (Homo sapiens)


name: TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains  (Rattus norvegicus)


name: methylamine dehydrogenase (amicyanin) activity


name: HMGCLL1:Mg2+ cleaves bHMG-CoA to Ac-CoA and ACA (Sus scrofa)


name: activation of exo-alpha-sialidase activity


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Danio rerio)


name: Demethylase KDM4C binds KLK2 and KLK3 promoters (Rattus norvegicus)


name: GP1b-IX-V binds 14-3-3-zeta (Rattus norvegicus)


name: [isocitrate dehydrogenase (NADP+)] kinase activity


name: I(1,4,5)P3 binds ITPR3 tetramer (Canis familiaris)


name: "With an iron-sulfur protein as acceptor"


name: NR1H2,3 binds the CETP gene (Homo sapiens)


name: Fibrillin microfibril assembly (Mus musculus)


name: negative regulation of macrophage colony-stimulating factor signaling pathway


name: TP53 binds POU4F1 (Drosophila melanogaster)


name: 2Fe-2S is inserted in UQCRFS1 (Schizosaccharomyces pombe)


name: phytyl phosphate + CTP => phytyl diphosphate + CDP


name: N-octadecanoyl-L-phenylalanine + H2O => octadecanoate + L-phenylalanine


name: FN3KRP phosphorylates PsiAm, RibAm (Caenorhabditis elegans)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Canis familiaris)


name: 2 a 1-acyl-sn-glycero-3-phosphocholine <=> sn-glycerol 3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: PML, TRIM27, PIAS1,2-1 SUMOylate MDM2 with SUMO1 (Rattus norvegicus)


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Saccharomyces cerevisiae)


name: 2xTPK1:Mg2+ phosphorylates THMN (Bos taurus)


name: CysS248-MPST:TXN2 dissociates (Homo sapiens)


name: P4HB:4-Hyp collagen propeptides dissociates (Canis familiaris)


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + NADP(+) => (2E,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADPH + H(+)


name: piceatannol + O2 <=> 3,5-dihydroxybenzaldehyde + 3,4-dihydroxybenzaldehyde


name: precorrin-5 + S-adenosyl-L-methionine + H2O = precorrin-6A + acetate + S-adenosyl-L-homocysteine + 2 H(+)


name: 3,4-dihydroxybenzoate + O2 => 4-carboxy-2-hydroxy-cis,cis-muconate 6-semialdehyde + H(+)


name: all-trans-retinol + hexadecanoyl-CoA <=> all-trans-retinyl hexadecanoate + CoA


name: 4-hydroxyphenylacetate + NADH + O2 + H(+) => homogentisate + NAD(+) + H2O


name: (6Z)-octadecenamide + H2O <=> (6Z)-octadecenoate + NH4(+)


name: tryprostatin B + NADPH + O2 + H(+) <=> demethoxyfumitremorgin C + NADP(+) + 2 H2O


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Gallus gallus)


name: structural constituent of presynaptic active zone


name: 3-phenylpropanoate + ATP + NADPH + H(+) <=> 3-phenylpropanal + AMP + diphosphate + NADP(+)


name: I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus (Sus scrofa)


name: all-trans-4-hydroxyretinoate + UDP-alpha-D-glucuronate = all-trans-4-hydroxy-4-O-(beta-D-glucuronide)-retinoate + UDP + H(+)


name: NRAMP1 transports divalent metal ions across phagosomal membranes of macrophages (Rattus norvegicus)


name: STAT4 binds IL12RB2:IL12RB2 (Gallus gallus)


name: D-arabinose 5-phosphate + phosphoenolpyruvate + H2O => 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate


name: Dissociation of insulin from insulin receptor (Homo sapiens)


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Canis familiaris)


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Rattus norvegicus)


name: formate(in) + chloride(out) <=> formate(out) + chloride(in)


name: glyoxylate(in) + sulfate(out) = glyoxylate(out) + sulfate(in)


name: Phosphorylation of nephrin by FYN (Bos taurus)


name: ASIC3 channel blockers bind ASIC3 trimer (Drosophila melanogaster)


name: Formation of ORC(1-5) complex (Canis familiaris)


name: Arachidonate is oxidised to PGG2 by PTGS1 (Bos taurus)


name: (2E)-dodecenoyl-CoA + NADH + H(+) <=> dodecanoyl-CoA + NAD(+)


name: INF-gamma induced phosphorylation of L13a (Homo sapiens)


name: 2'-deoxyadenosine + H2O + H(+) <=> 2'-deoxyinosine + NH4(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine => a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine


name: carbonyl sulfide + H2O = hydrogen sulfide + CO2 + H(+)


name: SLX1A:SLX4 binds MUS81:EME1,(MUS81:EME2) (Sus scrofa)


name: LRP2 binds extracellular TCN2:RCbl (Mus musculus)


name: ERK1/2/5 activate RSK1/2/3 (Mus musculus)


name: indole-3-acetyl-1D-myo-inositol + UDP-beta-L-arabinopyranose <=> (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + UDP + H(+)


name: selenite(out) + Zn(2+)(out) + hydrogencarbonate(out) = selenite(in) + Zn(2+)(in) + hydrogencarbonate(in)


name: SRC-1 phosphorylates SHB (Canis familiaris)


name: Nuclear VBC complex ubiquitinylates HIF-alpha (Rattus norvegicus)


name: 1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid => a 1-acylglycerone 3-phosphate + hexadecanoate


name: a tetracycline + NADPH + O2 + H(+) => an 11a-hydroxytetracycline + NADP(+) + H2O


name: cytidine 5'-({hydroxy[(S)-2-hydroxypropyl]phosphonoyl}phosphate) + H2O <=> (S)-2-hydroxypropylphosphonate + CMP + H(+)


name: (3R)-beta-leucine + NAD(+) + H2O => 4-methyl-3-oxopentanoate + NH4(+) + NADH + H(+)


name: Defective RPIA does not isomerize R5P to RU5P (Homo sapiens)


name: GSK3 phosphorylates p-GLI3 (Homo sapiens)


name: POLG in the replisome polymerizes the L strand (Bos taurus)


name: (R)-lactaldehyde + NAD(+) => methylglyoxal + NADH + H(+)


name: 4-nitrocatechol + NAD(+) + H2O => 4-nitrophenol + NADH + O2 + H(+)


name: carbamate + ATP => carbamoyl phosphate + ADP


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Xenopus tropicalis)


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated


name: "With 2-oxoglutarate as one donor, and the other dehydrogenated"


name: (+)-malbrancheamide + FADH2 => (+)-isomalbrancheamide B + FAD + chloride + 2 H(+)


name: Classical Complement Pathway Inhibitors [MoA]


name: (2E,6E)-farnesyl diphosphate <=> beta-acoradiene + diphosphate


name: 2'-O-methylcytidine(34) in tRNA + S-adenosyl-L-homocysteine + H(+) => cytidine(34) in tRNA + S-adenosyl-L-methionine


name: VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Mus musculus)


name: negative regulation of o-orsellinic acid biosynthetic process


name: an 11beta-hydroxysteroid + NADP(+) <=> an 11-oxosteroid + NADPH + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) => a CDP-1,2-diacyl-sn-glycerol + diphosphate


name: (+)-5-epi-aristolochene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 <=> capsidiol + 2 oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)


name: Disulfiram covalently modifies Cys191 in GSDMD (Rattus norvegicus)


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)


name: juglone-sensitive cis-trans proline isomerase activity


name: apo-Transferrin dissociates from the receptor complex (Gallus gallus)


name: Formation of the inner ring of the 20S thymoproteasome core particle (Homo sapiens)


name: PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O (Danio rerio)


name: carnosine(out) + 2 H(+)(out) = carnosine(in) + 2 H(+)(in)


name: aldehyde reductase (NADPH-dependent) activity


name: 5-fluorouridine + ATP <=> 5-fluorouridine 5'-phosphate + ADP + H(+)


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Caenorhabditis elegans)


name: (2E)-geranyl diphosphate + H2O <=> (S)-alpha-terpineol + diphosphate


name: L-seryl-[protein] + GDP-beta-L-fucose <=> 3-O-(alpha-L-fucosyl)-L-seryl-[protein] + GDP + H(+)


name: a 1-acyl-2-(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA => a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA


name: E-selectin binds E-selectin ligand (Caenorhabditis elegans)


name: Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex  (Sus scrofa)


name: Formation of GINS complex (Dictyostelium discoideum)


name: a (2S,3R)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 NADPH + 2 H(+)


name: (S)-2-hydroxypropyl-coenzyme M + NAD(+) <=> 2-oxopropyl-coenzyme M + NADH + H(+)


name: 3-dehydro-6-deoxo-28-norteasterone + reduced [NADPH--hemoprotein reductase] + O2 => 3-dehydro-6alpha-hydroxy-28-norteasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+)


name: iodomethane + S-adenosyl-L-homocysteine => iodide + S-adenosyl-L-methionine


name: RAP1A exchanges GDP for GTP (Saccharomyces cerevisiae)


name: (R)-carnitinamide + H2O => (R)-carnitine + NH4(+)


name: NPM1-ALK- and STAT3-dependent ICOS gene expression (Homo sapiens)


name: cholest-4-en-3-one + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (25R)-3-oxocholest-4-en-26-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: oxalate transmembrane transporter activity


name: (11R)-carlactone + reduced [NADPH--hemoprotein reductase] + O2 => (11R)-19-hydroxycarlactone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: cGMP dissociates from CNG channels (Sus scrofa)


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Xenopus tropicalis)


name: octyl acetate + CoA => octan-1-ol + acetyl-CoA


name: inhibition of FeMoco biosynthetic process


name: 3-(4-hydroxyphenyl)pyruvate + L-kynurenine => kynurenate + L-tyrosine + H2O


name: POLD,POLE binds deISGylated PCNA after TLS (Dictyostelium discoideum)


name: PYCR3 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Dictyostelium discoideum)


name: 3 reduced coenzyme F420-(gamma-L-Glu)(n) + sulfite => 3 oxidized coenzyme F420-(gamma-L-Glu)(n) + hydrogen sulfide + 3 H2O + 2 H(+)


name: D-galactonate(out) + H(+)(out) => D-galactonate(in) + H(+)(in)


name: PLD6 dimer hydrolyses cardiolipin to PA and PG (Rattus norvegicus)


name: Decreased Striated Muscle Endorphin Activity


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Mus musculus)


name: Caspase-mediated cleavage of Tau (Drosophila melanogaster)


name: 4-hydroxyestrone + NH4(+) + O2 = pyridinestrone carboxylate + 2 H2O + 2 H(+)


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-9Z-octadecenoyl)-ethanolamine + H2O <=> 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + N-(9Z-octadecenoyl) ethanolamine + H(+)


name: hexan-1-ol + hexanoyl-CoA <=> hexyl hexanoate + CoA


name: copper, zinc superoxide dismutase activity


name: Activated FGFR2:p-FRS bind to PPTN11 (Canis familiaris)


name: Association of MRE11 with RAD50 (Gallus gallus)


name: losartan + UDP-alpha-D-glucuronate => losartan-1-N-beta-D-glucuronide + UDP


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Xenopus tropicalis)


name: UTP + NH4(+) + ATP = CTP + ADP + phosphate + 2 H(+)


name: TRAF2,6 ubiquitinates NLRC5 (Bos taurus)


name: O-acetyl-(R)-carnitine + CoA => (R)-carnitine + acetyl-CoA


name: (2E,4E)-2,4-dichloromuconate + 2 H(+) => 3,5-dichlorocatechol + O2


name: pseudooxynicotine + 2 Fe(III)-[cytochrome c] + H2O = 4-oxo-4-(pyridin-3-yl)butanal + methylamine + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: GFI1 gene expression is enhanced by CEBPA (Homo sapiens)


name: peonidin + UDP-alpha-D-glucose = peonidin 3-O-beta-D-glucoside + UDP


name: malonamoyl-[OxyC ACP] + 8 malonyl-CoA + 8 H(+) <=> 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC ACP] + 8 CO2 + 8 CoA


name: TNF-α:TNFR1:NSMAF binds GNB2L1 (Homo sapiens)


name: endothelium-derived relaxation factor-forming enzyme activity


name: (3R,4S,5R)-3,4,5,6-tetrahydroxy-2-oxohexanoate => D-glyceraldehyde + 3-hydroxypyruvate


name: vanillin + L-alanine = vanillylamine + pyruvate


name: an N-(acyl)-sphingosylphosphoethanolamine => an N-(acyl)-sphingosyl-1,3-cyclic phosphate + ethanolamine


name: Complement factor H binds to surface-bound C3b (Gallus gallus)


name: p-6Y-VEGFR2 binds FYN (Xenopus tropicalis)


name: N-(D-erythrulosyl)-cadaverine + ATP <=> N-(3-O-phospho-D-erythrulosyl)-cadaverine + ADP + H(+)


name: 2 reduced [2Fe-2S]-[ferredoxin] + NAD(+) + 3 H(+)(in) = 2 oxidized [2Fe-2S]-[ferredoxin] + NADH + 2 H(+)(out)


name: CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) (Xenopus tropicalis)


name: CCND1 recruits HDAC4 to RUNX3 (Homo sapiens)


name: Dopa is oxidized to dopaquinone by TYR (Rattus norvegicus)


name: L-histidine + 2-oxoglutarate => 3-(imidazol-5-yl)pyruvate + L-glutamate


name: 4-aminobenzoate + all-trans-hexaprenyl diphosphate <=> 4-amino-3-(all-trans-hexaprenyl)benzoate + diphosphate


name: Binding of IRS to insulin receptor (Rattus norvegicus)


name: PGH2 is isomerised to PGD2 by PTGDS (Sus scrofa)


name: p-STAT1, p-Y-STAT2, p-STAT3, p-STAT4, p-STAT5 dissociates from IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:p-STAT1,p-STAT2,p-STAT3,p-STAT4,p-STAT5 (Homo sapiens)


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 = 1-O-methyl-(9R)-hydroperoxy-(10E,12Z)-octadecadienoate


name: glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity


name: ACSS3 ligates CoA to CH3COO- (Dictyostelium discoideum)


name: FOXG1 binds FOXO:SMAD complexes (Sus scrofa)


name: a triacylglycerol + CoA => a 1,2-diacylglycerol + a fatty acyl-CoA


name: The COG complex binds RABs at the Golgi membrane (Homo sapiens)


name: 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA => 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: K+-independent Li+/Ca2+ exchanger transport (Sus scrofa)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Schizosaccharomyces pombe)


name: (15Z)-tetracosenoyl-CoA + NADP(+) => (2E,15Z)-tetracosadienoyl-CoA + NADPH + H(+)


name: Diacylgycerol activates Protein kinase C, alpha type (Gallus gallus)


name: (2E,6E)-farnesal + NAD(+) + H2O = (2E,6E)-farnesoate + NADH + 2 H(+)


name: CYP4V2 omega-hydroxylates DHA to HDoHE (Homo sapiens)


name: malonyl-[ACP] + hexadecanoyl-CoA + H(+) = 3-oxooctadecanoyl-[ACP] + CO2 + CoA


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Caenorhabditis elegans)


name: (R)-glycerate + NAD(+) <=> 3-hydroxypyruvate + NADH + H(+)


name: 4-chlorobenzoyl-CoA + H2O => 4-hydroxybenzoyl-CoA + chloride + H(+)


name: (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+) <=> 3-[(E)-2-isocyanovinyl]indole + succinate + 2 CO2 + H2O


name: FGFR4 binds to FGF (Drosophila melanogaster)


name: WLS binds WNT ligands in the Golgi (Caenorhabditis elegans)


name: Interaction of SIGLEC14/15/16 and DAP12 (Rattus norvegicus)


name: I3P is dephosphorylated to Ins by IMPA1/2 in the cytosol (Xenopus tropicalis)


name: NRXNs bind CASK:Protein 4.1 (Caenorhabditis elegans)


name: ATP hydrolysis by HSP70 (Xenopus tropicalis)


name: ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Sus scrofa)


name: CYP24A1 24-hydroxylates CTL (Mus musculus)


name: inositol diphosphate tetrakisphosphate diphosphatase activity


name: 5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Saccharomyces cerevisiae)


name: heptanedioate(in) + 2-oxoglutarate(out) => heptanedioate(out) + 2-oxoglutarate(in)


name: ENPP6 hydrolyzes lysophosphatidylcholine (Homo sapiens)


name: TRADD:TRAF2:RIP1:FADD binds pro-caspase 8   (Homo sapiens)


name: L-aspartate(in) + L-glutamate(out) + H(+)(out) => L-aspartate(out) + L-glutamate(in) + H(+)(in)


name: 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H2O <=> sn-glycero-3-phospho-L-serine + hexadecanoate + H(+)


name: GDP-alpha-D-perosamine + 2-oxoglutarate = GDP-4-dehydro-alpha-D-rhamnose + L-glutamate


name: 4-methyl-2-oxopentanoate + glycine => L-leucine + glyoxylate


name: (5R)-5-hydroxy-L-lysyl-[collagen] + succinate + CO2 => L-lysyl-[collagen] + 2-oxoglutarate + O2


name: DDX41 binds bacterial c-di-AMP, c-di-GMP   (Drosophila melanogaster)


name: Melanocortin receptors bind melanocortins (Mus musculus)


name: Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Rattus norvegicus)


name: cholesterol + PAPS => cholesterol sulfate + PAP (Sus scrofa)


name: USP8 deubiquitinates LRIG1 (Homo sapiens)


name: cyclohexanone + NADPH + O2 + H(+) => hexano-6-lactone + NADP(+) + H2O


name: 2,4,6-trinitrotoluene + NADPH <=> 4-methyl-1,3,5-trinitrocyclohexa-2,4-dien-1-ide + NADP(+)


name: a 3',5'-dimethoxyflavone + S-adenosyl-L-homocysteine + H(+) => a 5'-hydroxy-3'-methoxyflavone + S-adenosyl-L-methionine


name: Phosphorylation of L1 by ERK (Drosophila melanogaster)


name: pre-sodorifen diphosphate => sodorifen + diphosphate


name: 1,2-dihexadecanoyl-sn-glycerol + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: SCF-FBXL7 ubiquitinates AURKA (Dictyostelium discoideum)


name: factor VII -> factor VIIa (Rattus norvegicus)


name: N-acyl-1-deoxysphing-14Z-enine + 2 Fe(III)-[cytochrome b5] + 2 H2O => N-acyl-1-deoxysphinganine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: (E)-ferulate + NADH + H(+) => dihydroferulate + NAD(+)


name: a (2E)-enoyl fatty acid + holo-[ACP] + ATP = a (2E)-enoyl-[ACP] + AMP + diphosphate


name: 1-seleno-beta-D-galactose + UDP + phosphate + H(+) => selenophosphate + UDP-alpha-D-galactose + H2O


name: MADCAM1-1 binds Integrin alpha4beta7 (Rattus norvegicus)


name: DLAT trimer transfers acetyl to CoA (Schizosaccharomyces pombe)


name: RANBP2 SUMOylates PML with SUMO1 (Sus scrofa)


name: 3-dehydro-L-gulonate 6-phosphate + H(+) => L-xylulose 5-phosphate + CO2


name: [ribosomal protein uS12]-(3S)-3-hydroxy-L-proline + 2-oxoglutarate + O2 <=> [ribosomal protein uS12]-(3S)-3,4-dihydroxy-L-proline + succinate + CO2


name: Endocytosis of TLR4:LY96:LPS:CD14 (Gallus gallus)


name: Dissociation of cytosolic HSF1:HSP90 complex (Mus musculus)


name: CBL ubiquitinates PI3K (Xenopus tropicalis)


name: L-ornithine + O2 + H2O <=> 5-amino-2-oxopentanoate + H2O2 + NH4(+)


name: L-methionyl-L-alanine + H2O = L-alanine + L-methionine


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus (Sus scrofa)


name: guanosine(46) in tRNA + S-adenosyl-L-methionine => N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine


name: a 2'-deoxyuridine in double-stranded DNA + NH4(+) => a 2'-deoxycytidine in double-stranded DNA + H2O + H(+)


name: 2-demethylmenaquinol-7 + CO2 + diphosphate => all-trans-heptaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate + H(+)


name: 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O => D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate


name: GNB1,3:GNG13:PLCB2:Ca2+ hydrolyzes PI(4,5)P2 to I(1,4,5)P3 and DAG (Homo sapiens)


name: 3 (R)-3-phenyllactate + (R)-lactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022C + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)


name: N(omega),N(omega)-dimethyl-L-arginine(in) + L-lysine(out) <=> N(omega),N(omega)-dimethyl-L-arginine(out) + L-lysine(in)


name: obsolete serine-type Pro-X carboxypeptidase activity


name: UDP-alpha-D-glucuronate + H2O => D-glucuronate + UDP + H(+)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-(4R)-hydroxysphinganine + H2O <=> (4R)-hydroxysphinganine + (5Z,8Z,11Z,14Z)-eicosatetraenoate


name: 4-methyl-2-oxopentanoate(in) + H(+)(in) => 4-methyl-2-oxopentanoate(out) + H(+)(out)


name: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) => 5-amino-6-(D-ribitylamino)uracil + riboflavin


name: LTA trimer binds TNFRSF1A,1B,14 (Rattus norvegicus)


name: glycodeoxycholate + 3'-phosphoadenylyl sulfate = 3alpha-sulfoglycodeoxycholate + adenosine 3',5'-bisphosphate + H(+)


name: CSF3 dimer (GCSF dimer) binds CSF3R:JAK1:LYN (Homo sapiens)


name: alpha-D-Gal-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+) => N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose


name: Li(+)(out) + 2 hydrogencarbonate(out) + chloride(in) => Li(+)(in) + 2 hydrogencarbonate(in) + chloride(out)


name: levoglucosan + NAD(+) <=> 3-dehydrolevoglucosan + NADH + H(+)


name: Gbeta:gamma recruits PI3K gamma (Mus musculus)


name: p-4Y-PLCG1 dissociates from activated FGFR2 (Rattus norvegicus)


name: NEXT2 is cleaved to produce NICD2 (Homo sapiens)


name: 6-acetamido-2-oxohexanoate + NAD(+) + H2O <=> 5-acetamidopentanoate + CO2 + NADH + H(+)


name: p-IRF7:p-IRF7 translocates to the nucleus (Gallus gallus)


name: Initial activation of proMMP7 by trypsin (Canis familiaris)


name: SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling (Bos taurus)


name: AMP + diphosphate => 5-phospho-alpha-D-ribose 1-diphosphate + adenine


name: ethylamine + NAD(+) + H2O = acetaldehyde + NH4(+) + NADH + H(+)


name: SQSTM1 oligomerizes (Caenorhabditis elegans)


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Mus musculus)


name: MET phosphorylates SHC1-2 (Homo sapiens)


name: Activation of linoleic acid to linoleoyl-CoA (Xenopus tropicalis)


name: Assembly of EGFR complex in clathrin-coated vesicles (Gallus gallus)


name: cholesteryl (9Z,12Z)-octadecadienoate(in) <=> cholesteryl (9Z,12Z)-octadecadienoate(out)


name: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine <=> 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: (2E,6E)-farnesyl diphosphate <=> beta-maaliene + diphosphate


name: (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(in) + ATP + H2O <=> (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside(out) + ADP + phosphate + H(+)


name: DAG activation of TRPC channels (Rattus norvegicus)


name: B4GALTs transfer Gal to the keratan chain (Canis familiaris)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Gallus gallus)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Sus scrofa)


name: kynurenate + AH2 + O2 <=> 7,8-dihydro-7,8-dihydroxykynurenate + A


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Rattus norvegicus)


name: D-allose 6-phosphate + ADP + H(+) => D-allose + ATP


name: dihydroouabain + 2 Fe(III)-[cytochrome c] => ouabain + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + 3-methyl-2-oxobutanoate + H(+) => N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] + CO2


name: CARM1 methylates arginine-18 (H3R17) of histone H3 (Mus musculus)


name: Recruitment of AP-2 complex and clathrin (Mus musculus)


name: fumitremorgin A + diphosphate => verruculogen + dimethylallyl diphosphate


name: cAMP degradation by Phosphodiesterases (Caenorhabditis elegans)


name: 3-oxo-5beta-cholan-24-oate + NADPH + H(+) => lithocholate + NADP(+)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Bos taurus)


name: IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Bos taurus)


name: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + NADH + H(+)


name: ZnT5 transports zinc into the golgi apparatus (Homo sapiens)


name: taurocholate(out) + 2-oxoglutarate(in) => taurocholate(in) + 2-oxoglutarate(out)


name: DENND3 exchanges GTP for GDP on RAB12 (Homo sapiens)


name: IDS hydrolyses Heparan sulfate chain(5) (Drosophila melanogaster)


name: CYP2A13 oxidises AFM1 to AFM1E (Dictyostelium discoideum)


name: ATM:PEX5 translocates from cytosol to peroxisomal membrane (Drosophila melanogaster)


name: 8-oxoguanine + H2O + H(+) => urate + NH4(+)


name: Translocation of PLC-gamma1 to PIP2 (Bos taurus)


name: a globoside NOR1 + UDP-N-acetyl-alpha-D-galactosamine <=> a globoside NORint + UDP + H(+)


name: PIAS3 SUMOylates RELA with SUMO3 (Mus musculus)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Caenorhabditis elegans)


name: activation of metalloendoprotease activity involved in APP catabolic process


name: Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Homo sapiens)


name: ORC1 binds to H4K20me2 (Plasmodium falciparum)


name: Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Danio rerio)


name: Bitter compound binds bitter taste receptor (TAS2R) (Canis familiaris)


name: dTDP-beta-L-evernosamine + 2 NADPH + 2 O2 + H(+) = dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + 2 NADP(+) + 3 H2O


name: regulation of cbb3-type cytochrome c oxidase


name: epothilone D + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) <=> epothilone B + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: CASTOR1 in CASTOR1:CASTOR2 binds L-arginine and dissociates from GATOR2 (Rattus norvegicus)


name: Factor B binds to surface-associated C3b (Mus musculus)


name: apigenin + UDP-alpha-D-glucose = isovitexin + UDP + H(+)


name: 2'-deoxyuridine(in) + H(+)(in) = 2'-deoxyuridine(out) + H(+)(out)


name: 2-cis-(+)-abscisate + UDP-alpha-D-glucose => beta-D-glucopyranosyl cis-(+)-abscisate + UDP


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Caenorhabditis elegans)


name: (11R,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O => (11S,12S)-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate


name: RHOD binds effectors at the mitochondrial outer membrane (Bos taurus)


name: (R)-2-hydroxyhexadecanoate + O2 => pentadecanoate + CO2 + H2O


name: L-tryptophyl-[protein] + (2E,6E)-farnesyl diphosphate <=> (2S,3R)-3-farnesyl-2,3-dihydro-2,N(alpha)-cyclo-L-tryptophyl-[protein] + diphosphate


name: (S)-2-amino-6-oxoheptanedioate + NH4(+) + NADPH + H(+) => meso-2,6-diaminoheptanedioate + NADP(+) + H2O


name: SLCO1A2 transports Cipro(1+) into the cytosol (Drosophila melanogaster)


name: HPN heterodimer cleaves pro-HGF to form HGF dimer (Canis familiaris)


name: (2E,6E,10E)-geranylgeranyl diphosphate = casbene + diphosphate


name: Trimerization of HSF1 in the nucleus (Homo sapiens)


name: Interaction of IRF9 with p-STAT2:p-STAT1 (Xenopus tropicalis)


name: positive regulation of DNA helicase activity


name: The complex of RUNX3, SMAD3 and SMAD4 binds the CDKN1A gene promoter (Homo sapiens)


name: (9Z)-octadecenoate + O2 <=> (8E,10S)-10-hydroperoxy-octadeca-8-enoate


name: ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 (Danio rerio)


name: D-galactonate <=> 2-dehydro-3-deoxy-D-galactonate + H2O


name: 1-octadecanoyl-2-(9,10-epoxyoctadecanoyl)-sn-glycero-3-phospho-L-serine + H2O = 9,10-epoxyoctadecanoate + 1-octadecanoyl-sn-glycero-3-phosphoserine + H(+)


name: 3-demethylubiquinol-8 + S-adenosyl-L-methionine <=> ubiquinol-8 + S-adenosyl-L-homocysteine + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O <=> phosphoethanolamine + a 1,2-diacyl-sn-glycerol + H(+)


name: 12S-HpETE is reduced to 12S-HETE by GPX1/2/4 (Sus scrofa)


name: 6'''-deamino-6'''-hydroxyneomycin C + O2 => 6'''-deamino-6'''-oxoneomycin C + H2O2


name: SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Drosophila melanogaster)


name: 4-nitrobenzaldehyde + NAD(+) + H2O => 4-nitrobenzoate + NADH + 2 H(+)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Sus scrofa)


name: (R)-reticuline + NADP(+) => 1,2-dehydroreticuline + NADPH + H(+)


name: (2S,4R)-bornyl diphosphate => (2E)-geranyl diphosphate


name: 3,3'-di-O-methyl-4alpha-mannobiose + S-adenosyl-L-methionine = 1,3,3'-tri-O-methyl-4alpha-mannobiose + S-adenosyl-L-homocysteine + H(+)


name: Arachidonate is hydroxylated to 16-HETE by CYP(1) (Canis familiaris)


name: ULK1 phosphorylates ATG13 and RB1CC1 (Mus musculus)


name: HDHD1:Mg2+ dephosphorylates PURIDP (Schizosaccharomyces pombe)


name: (9Z,12Z)-octadecadienoate + H2O = (12Z)-10-hydroxyoctadecenoate


name: KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Saccharomyces cerevisiae)


name: Decreased Sympathetic Serotonin Activity


name: negative regulation of protein adenylylation


name: deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Bos taurus)


name: Defective HK1 does not phosphorylate Glc to form G6P (Homo sapiens)


name: Ubiquitination of phospho-p27/p21 (Bos taurus)


name: phloretin + H2O <=> phloretate + 1,3,5-trihydroxybenzene + H(+)


name: (deoxy)cytidine + H2O => (deoxy)uridine + NH4+ (CDA) (Canis familiaris)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate => 1,2-dioctanoyl-sn-glycero-3-phospho-(1-D-myo-inositol-4-phosphate) + H2O


name: xanthogalenol + S-adenosyl-L-methionine <=> 4'-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)


name: a 4-saturated-(3S)-3-hydroxyacyl-CoA <=> a (3E)-enoyl-CoA + H2O


name: Connexin 45/Connexin 36 mediated neuronal gap junction communication (Canis familiaris)


name: butachlor + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = butyl formate + N-(2,6-diethylphenyl)-2-chloroacetamide + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Schizosaccharomyces pombe)


name: D-glyceraldehyde 3-phosphate + ADP + H(+) => D-glyceraldehyde + ATP


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Homo sapiens)


name: mating-type alpha-factor pheromone receptor activity


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Danio rerio)


name: ANO1 inhibitors bind ANO1 (Dictyostelium discoideum)


name: dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 => (11R)-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: L-homoserine + NADP(+) = L-aspartate 4-semialdehyde + NADPH + H(+)


name: SLC25A19 transports ThDP from cytosol to mitochondrial matrix (Caenorhabditis elegans)


name: PTK6 phosphorylates KHDRBS1 (Sus scrofa)


name: urate(out) + n chloride(in) <=> urate(in) + n chloride(out)


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Mus musculus)


name: SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Mus musculus)


name: 2'-deoxyadenosine(in) + H(+)(in) => 2'-deoxyadenosine(out) + H(+)(out)


name: (12E)-9alpha-labda-8(17),12,14-triene + diphosphate => 9alpha-copalyl diphosphate


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Saccharomyces cerevisiae)


name: PITPNM1,2,3 exchange PI for PA (Sus scrofa)


name: (1S,2R,4S)-neodihydrocarveol + NAD(+) <=> (1S,4S)-dihydrocarvone + NADH + H(+)


name: HCMV Formation of Final Envelopment Complex (Homo sapiens)


name: activation of tyrosine phosphorylation of Stat6 protein


name: a ganglioside GT1b + H2O = a ganglioside GD1b + N-acetylneuraminate


name: beta-alanine(out) + n H(+)(in) = beta-alanine(in) + n H(+)(out)


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Gallus gallus)


name: "Linked to the hydrolysis of diphosphate"