name: Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it (Bos taurus)


name: D-serine(out) + chloride(out) + 2 Na(+)(out) = D-serine(in) + chloride(in) + 2 Na(+)(in)


name: IL21 receptor STAT phosphorylation (Rattus norvegicus)


name: XPC binds RAD23 and CETN2 (Plasmodium falciparum)


name: bicarbonate:monoatomic anion antiporter activity


name: PGE2 is converted to PGF2a by CBR1 (Danio rerio)


name: RPA binds to the Flap (Drosophila melanogaster)


name: L-pipecolate + A => L-1-piperideine-6-carboxylate + AH2 + H(+)


name: a ganglioside GD3 (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT3 (d18:1(4E)) + CMP + H(+)


name: P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration


name: an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O => 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)


name: SYK binds the activated BCR (Rattus norvegicus)


name: 4-phospho-D-erythronate + NAD(+) => (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + NADH + H(+)


name: 3beta-hydroxy-5alpha-androstan-17-one + UDP-alpha-D-glucose = epiandrosterone 3-beta-D-glucoside + UDP + H(+)


name: Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2 (Mus musculus)


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Schizosaccharomyces pombe)


name: B-WICH recruits histone acetyltransferases (Canis familiaris)


name: PTPN3 dephosphorylates EPS15 (Caenorhabditis elegans)


name: AUF1 binds translation and heat shock proteins (Sus scrofa)


name: Activated TLR2/4:TIRAP interacts with BTK (Homo sapiens)


name: PAQR3 binds inactive RAFs (Xenopus tropicalis)


name: GLI2,3 are degraded by the proteasome (Xenopus tropicalis)


name: eIF2 activation (Saccharomyces cerevisiae)


name: p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Mus musculus)


name: anthranilate + malonyl-CoA <=> N-malonylanthranilate + CoA


name: L-aspartate + 2-oxoglutarate <=> oxaloacetate + L-glutamate


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 => (5Z,7Z,8Z,10E,14Z,17Z)-12-hydroperoxyeicosapentaenoate


name: SUMOylation of Histone H4 with SUMO1 (Bos taurus)


name: (2R)-hydroxyoctanoate + FAD + H(+) => 2-oxooctanoate + FADH2


name: propylamine + NAD(+) + H2O = propanal + NH4(+) + NADH + H(+)


name: DNAJC3 binds PKR (Drosophila melanogaster)


name: CYLD deubiquitinates NEMO (Canis familiaris)


name: RND1 binds effectors (Saccharomyces cerevisiae)


name: 2-(dihydroxymethyl)-5-formylfuran + O2 => 2-carboxy-5-formylfuran + H2O2 + H(+)


name: apo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + biotin + ATP => holo-[propionyl-CoA:carbon-dioxide ligase (ADP-forming)] + AMP + diphosphate + H(+)


name: kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity


name: FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)


name: ALOX15 dehydrogenates 17(R)-Hp-DHA to 17R(16)-epoxy-DHA (Homo sapiens)


name: a 3'-end 2'-deoxyribonucleotide-8-oxoguanine-DNA + H2O <=> 8-oxo-dGMP + a 3'-end 2'-deoxyribonucleotide-DNA + H(+)


name: HSP90:FKBP4:PTGES3 binds HSF1 trimer (Gallus gallus)


name: RAC2 binds effectors at the mitochondrial outer membrane (Rattus norvegicus)


name: oxaloacetate(in) + 3 Na(+)(in) => oxaloacetate(out) + 3 Na(+)(out)


name: Inner coat assembly and cargo binding (Caenorhabditis elegans)


name: Cleaved KMT2A dimers translocate to the nucleus (Homo sapiens)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Sus scrofa)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Gallus gallus)


name: NLRX1 inhibits MAVS-DDX58 interaction (Homo sapiens)


name: BCHE hydrolyzes ASA- (Xenopus tropicalis)


name: Prokineticin receptors bind prokineticin (Mus musculus)


name: a (2R,3R)-flavan-3-ol + 2 NAD(+) = an anthocyanidin with a 3-hydroxy group + 2 NADH + 2 H(+)


name: E-selectin binds E-selectin ligand (Danio rerio)


name: p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Drosophila melanogaster)


name: hexadecanoyl-CoA + H2O = S-hexadecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+)


name: 3-phenylpropanoate + NADH + O2 + H(+) = 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)


name: D-amino acid transmembrane transporter activity


name: methylmalonate + CoA + H(+) => (S)-methylmalonyl-CoA + H2O


name: cholesterol + PAPS => cholesterol sulfate + PAP (Rattus norvegicus)


name: Aquaporins passively transport glycerol into cells (Sus scrofa)


name: G alpha (13) activates Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (Rattus norvegicus)


name: ARSC hydrolyzes steroid sulfates (Rattus norvegicus)


name: Recruitment of Telomerase RNP to the Telomeric Chromosome End (Sus scrofa)


name: inhibition of C-C motif chemokine 20 production


name: Ubiquitination of stimulated EGFR (CBL:GRB2) (Canis familiaris)


name: eicosanoate + glycine => N-eicosanoylglycinate + H2O


name: L-isoleucine + 2-oxoglutarate + O2 <=> 3(1)-hydroxy-L-isoleucine + succinate + CO2


name: N(epsilon)-GMP-L-lysyl-[protein] + a 5'-end diphospho-(purine-ribonucleoside) in mRNA + 2 H(+) => a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + L-lysyl-[protein]


name: DIT and MIT combine to form triiodothyronine (Drosophila melanogaster)


name: COPI vesicle uncoating at the ER (Homo sapiens)


name: 4alpha-formyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycerol + phosphocholine + H(+)


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Canis familiaris)


name: (2R,5R)-isopulegone + NADP(+) => (6R)-isopiperitenone + NADPH + H(+)


name: POMC(138-176) binds MC2R (Rattus norvegicus)


name: The retrograde IFT train dissociates (Rattus norvegicus)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Homo sapiens)


name: FYN-mediated phosphorylation of GRIN2B (Homo sapiens)


name: all-trans-10'-apo-beta-carotenal + O2 <=> beta-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial


name: GSDMD forms ring‐shaped oligomers  (Rattus norvegicus)


name: (20S)-ginsenoside Rd + H2O => (20S)-ginsenoside Rg3 + D-glucose


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CMP + H(+) => 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + CDP-choline


name: RNF146 binds RibC-AXIN:TNKS complex (Mus musculus)


name: USP49 deubiquitinates H2B (Dictyostelium discoideum)


name: N-dodecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-dodecanoylethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: ethanol + acetyl-CoA <=> ethyl acetate + CoA


name: trihazone A + 2-oxoglutarate + O2 + H(+) <=> trihazone D + succinate + 2 CO2 + H2O


name: SRD5A3 reduces pPNOL to DCHOL (Saccharomyces cerevisiae)


name: L-cysteine + ATP + H(+) => L-cysteinyl-5'-AMP + diphosphate


name: L-aspartate(out) + ATP + H2O = L-aspartate(in) + ADP + phosphate + H(+)


name: PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Saccharomyces cerevisiae)


name: L-tyrosine + dimethylallyl diphosphate <=> 4-O-dimethylallyl-L-tyrosine + diphosphate


name: a ganglioside GM1 + N-acetylneuraminate => a ganglioside GD1a + H2O


name: GTP + ATP => guanosine 3'-diphosphate 5'-triphosphate + AMP


name: LIMK phosphorylates CFL1, inactivating it (Homo sapiens)


name: Formation of eIF2:GDP:eIF2B intermediate (Caenorhabditis elegans)


name: PYGB dimer, b form + 2 AMP <=> PYGB b dimer:AMP complex (Homo sapiens)


name: a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine => a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: protein C-terminal leucine carboxyl O-methyltransferase activity


name: pyrrole-2-carboxylate + H(+) => 1H-pyrrole + CO2


name: a (3E)-enoyl-CoA => a 4-saturated (2E)-enoyl-CoA


name: 2,7-dihydroxy-5-methyl-1-naphthoate + S-adenosyl-L-methionine = 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + S-adenosyl-L-homocysteine + H(+)


name: 2-heptyl-1-methoxy-4(1H)-quinolinone + S-adenosyl-L-homocysteine + H(+) => 2-heptyl-1-hydroxy-4(1H)-quinolinone + S-adenosyl-L-methionine


name: Furin cleaves pro-protein C to protein C (Danio rerio)


name: (Z)-gamma-bisabolene + diphosphate => (2E,6E)-farnesyl diphosphate


name: nitric oxide + L-tyrosine + reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) <=> 3-nitro-L-tyrosine + oxidized [2Fe-2S]-[ferredoxin] + H2O


name: positive regulation of D-erythro-sphingosine kinase activity


name: L-galactose(out) + H(+)(out) = L-galactose(in) + H(+)(in)


name: positive regulation of L-glutamate uptake


name: K63polyUb-RIPK1 is deubiquitinated (Danio rerio)


name: FASL binds FAS Receptor (Xenopus tropicalis)


name: BAD displaces tBID from BCL-2 sequestration (Xenopus tropicalis)


name: positive regulation of phospholipase A2 activity


name: Full-length TLR3/7/8/9 binds to UNC93B1 (Gallus gallus)


name: DPP4 binds DPP4 inhibitors (Gallus gallus)


name: USP25 deubiquitinates DDX58 (Sus scrofa)


name: 2-methylcholine + CO2 => carnitine + H(+)


name: down regulation of 17-OH steroid UDPGT activity


name: NADK2 dimer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)


name: D-erythronate + ATP = 4-phospho-D-erythronate + ADP + H(+)


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Canis familiaris)


name: RHOA:GTP:Mg2+ binds ROCK1,ROCK2 (Bos taurus)


name: 6-acetamido-2-oxohexanoate + NAD(+) + H2O => 5-acetamidopentanoate + CO2 + NADH + H(+)


name: Cleavage of the 3'-end of the Histone Pre-mRNA (Rattus norvegicus)


name: phylloquinone + [protein]-disulfide + H2O <=> 2,3-epoxyphylloquinone + [protein]-dithiol


name: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O <=> 2 ADP + 2 H(+)


name: a ganglioside Ac-O-7-GD2(d18:1(4E)) + CoA => a ganglioside GD2 (d18:1(4E)) + acetyl-CoA


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Canis familiaris)


name: "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters"


name: p107 (RBL1) in complex with E2F4:DP1/2 binds to cyclin E/A:CDK2 (Rattus norvegicus)


name: SRY and NR5A1 (SF1) bind SOX9 gene (Homo sapiens)


name: inhibition of estriol UDPglucuronosyltransferase activity


name: LILRs interact with MHC Class I (Homo sapiens)


name: L-histidine + L-cysteine + O2 = L-alanin-3-yl L-histidin-5-yl sulfoxide + H2O


name: Protein E forms a homopentamer (Homo sapiens)


name: Expression of interferon-beta (Homo sapiens)


name: bornane-2,6-dione + H2O <=> [(1S)-4-hydroxy-2,2,3-trimethylcyclopent-3-enyl]acetate + H(+)


name: negative regulation of interleukin-35 production


name: 2 a Fe(II)-siderophore + NADP(+) + H(+) = 2 a Fe(III)-siderophore + NADPH


name: arachidonic acid 11,12-epoxygenase activity


name: 2-formylbenzoate + pyruvate => (3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O


name: TYSND1 cleaves TYSND1 (Dictyostelium discoideum)


name: lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate (Homo sapiens)


name: 2 Co(II)-[trimethylamine-specific corrinoid protein] + AH2 + ATP + H2O => 2 Co(I)-[trimethylamine-specific corrinoid protein] + A + ADP + phosphate + 3 H(+)


name: type 1 vasoactive intestinal polypeptide receptor ligand


name: a long-chain (2E)-enoyl-CoA + H2O2 => a long-chain 2,3-saturated fatty acyl-CoA + O2


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Homo sapiens)


name: regulation of type II site-specific deoxyribonuclease activity


name: ursodeoxycholate + NAD(+) => 7-oxolithocholate + NADH + H(+)


name: (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate = 3-hydroxypropyl isothiocyanate + sulfate


name: D-glucuronate + ATP => 1-phospho-alpha-D-glucuronate + ADP + H(+)


name: (9Z)-octadecenoyl-CoA + AMP + diphosphate => (9Z)-octadecenoate + ATP + CoA


name: 1,2-di-(9Z)-octadecenoyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine => 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycerol


name: 3-oxoeicosanoyl-[ACP] + NADPH + H(+) <=> 3R-hydroxyeicosanoyl-[ACP] + NADP(+)


name: POLB excises the NEIL1,NEIL2-bound AP site (5'dRP) (Xenopus tropicalis)


name: pro-SFTPB translocates from ER membrane to multivesicle body (Sus scrofa)


name: Negative regulation of DDX58/IFIH1 signaling by RNF216 (Homo sapiens)


name: ADA catalyzes the deamination of (deoxy)adenosine (Bos taurus)


name: PDGF-AA clevage by Furin (Gallus gallus)


name: Autocleavage of ESPL1 (Separase) (Rattus norvegicus)


name: Arachidonate is oxidised to 12S-HpETE by ALOX12/15 (Dictyostelium discoideum)


name: 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP + H(+) => a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine


name: PHGDH tetramer dehydrogenates 3PG (Bos taurus)


name: UGT1A1 transfers GlcA from UDP-GlcA to BIL to form BMG (Homo sapiens)


name: 23S rRNA pseudouridine(746) synthase activity


name: THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)


name: Active LTK recruits GRB2:SOS1 (Mus musculus)


name: SPHK1 phosphorylates sphingosine in response to E2 stimulation (Mus musculus)


name: Exocytosis of azurophil granule lumen proteins (Bos taurus)


name: PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Schizosaccharomyces pombe)


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Sus scrofa)


name: Degradation of ubiquitinated SMAD2 (Drosophila melanogaster)


name: a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-seryl-[protein] + UDP + H(+)


name: a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-acyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: a beta-D-glucuronoside + H2O <=> D-glucuronate + an alcohol


name: IL17RA and IL17RB bind IL25 dimer (Homo sapiens)


name: 9alpha-copalyl diphosphate <=> (12E)-9alpha-labda-8(17),12,14-triene + diphosphate


name: SLC35D2 exchanges UDP-GlcNAc for UMP (Rattus norvegicus)


name: Disassembly of COPII coated vesicle (Rattus norvegicus)


name: 2-(prostaglandin G2)-sn-glycero-3-phosphocholine + AH2 = 2-(prostaglandin H2)-sn-glycero-3-phosphocholine + A + H2O


name: Truncated AMER1 mutants destabilize the destruction complex (Homo sapiens)


name: methylmalonate semialdehyde + NAD+ + CoA + H2O => propionyl-CoA + HCO3- + NADH + H+ (Caenorhabditis elegans)


name: pyridoxal 5'-phosphate + H2O2 => pyridoxine 5'-phosphate + O2


name: Interaction of Bcl10 to CARMA1 (Canis familiaris)


name: 3-bromo-4,5-dihydroxybenzoate + bromide + NADPH + O2 + 3 H(+) => 3,5-dibromobenzene-1,2-diol + CO2 + NADP(+) + 2 H2O


name: MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Canis familiaris)


name: Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Bos taurus)


name: stimulation of glucocorticoid catabolic process


name: Beta-catenin recruits SMARCA4 (Canis familiaris)


name: cAMP degradation by Phosphodiesterases (Bos taurus)


name: 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine <=> D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamate + H(+)


name: Caspase-8 and FLIP(L) processing at DISC (Canis familiaris)


name: MEMO1 binds RHOA:GTP:DIAPH1 (Sus scrofa)


name: iso-precytochalasin + NADPH + O2 + H(+) = cytochalasin Z16 + NADP(+) + H2O


name: L-phenylalanine(out) + chloride(out) + 2 Na(+)(out) = L-phenylalanine(in) + chloride(in) + 2 Na(+)(in)


name: positive regulation of ATF6-alpha UPR branch


name: LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) (Homo sapiens)


name: Neurolysin degrades neurotensin (Canis familiaris)


name: phycocyanobilin-L-cysteinyl(84)-[C-phycocyanin alpha-subunit] <=> apo-L-cysteinyl(84)-[C-phycocyanin alpha-subunit] + (2R,3E)-phycocyanobilin


name: KCNH2:KCNE transport K+ from cytosol to extracellular region (Mus musculus)


name: Dimeric TGF-beta-1 binds to the receptor (Gallus gallus)


name: ALG12 transfers Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 (Schizosaccharomyces pombe)


name: Cleaved KMT2A dimers translocate to the nucleus (Sus scrofa)


name: 5alpha-androst-1-ene-3,17-dione + A + H2O = 5alpha-androstan-1,3,17-trione + AH2


name: hexadecan-1-ol + NADP(+) => hexadecanal + NADPH + H(+)


name: (indol-3-yl)acetate + H(+) <=> skatole + CO2


name: [ADP-thiazole synthase]-L-cysteine + glycine + NAD(+) => [ADP-thiazole synthase]-dehydroalanine + ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + 3 H2O + 2 H(+)


name: PI3K produces PIP3 and other phosphatidyl inositides (Sus scrofa)


name: IL13 binds IL13RA:TYK2 (Rattus norvegicus)


name: 7alpha,25-dihydroxy-4-cholesten-3-one + NADH + H(+) => 7alpha,25-dihydroxycholesterol + NAD(+)


name: (9Z)-hexadecenoyl-CoA + cholesterol => cholesteryl (9Z)-hexadecenoate + CoA


name: L-hexahomomethionine + reduced [NADPH--hemoprotein reductase] + O2 <=> N-hydroxy-L-hexahomomethionine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: a 9-cis-epoxycarotenoid + O2 = a 12'-apo-carotenal + 2-cis,4-trans-xanthoxin


name: GPR31 is a receptor for 12(S)-HETE (Sus scrofa)


name: p60c-src protein tyrosine kinase activity


name: O-acetyl-L-serine + thiosulfate = S-sulfo-L-cysteine + acetate + H(+)


name: 8-oxo-dGMP + diphosphate + H(+) => 8-oxo-dGTP + H2O


name: 17-hydroxy-(9Z)-octadecenoate + UDP-alpha-D-glucose => (9Z)-17-hydroxyoctadec-9-enoate 17-O-beta-D-glucoside + UDP + H(+)


name: 4-hydroxy-N-methyltryptamine 4-phosphate + S-adenosyl-L-methionine => psilocybin + S-adenosyl-L-homocysteine + H(+)


name: p115-RhoGEF activation of RHOA (Bos taurus)


name: Cip/Kip CDK inhibitors bind CDK4/6:CCND complexes (Sus scrofa)


name: quillaic acid 28-beta-D-glucoside + UDP => quillate + UDP-alpha-D-glucose


name: Activated FGFR2 binds PLCG1 (Drosophila melanogaster)


name: Formation of caspase-1 p10/p20 dimer (Mus musculus)


name: 5beta-cholestan-3alpha, 7alpha-diol is translocated from the cytosol to the mitochondrial matrix (Homo sapiens)


name: Nsp3, nsp4, and nsp6 produce replicative organelles (Homo sapiens)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2 = (11S)-hydroperoxy-(4Z,7Z,9E,13Z,16Z,19Z)-docosahexaenoate


name: alpha-D-glucose 6-phosphate <=> D-fructose 6-phosphate (Saccharomyces cerevisiae)


name: Choloyl CoA reacts with glycine or taurine to form glycocholate or taurocholate (Canis familiaris)


name: UBA1 adenylates ubiquitin in the cytosol (Bos taurus)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Schizosaccharomyces pombe)


name: 2'-deoxyinosine + phosphate => dIMP + H2O


name: germacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2 <=> 8alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (+)-copalyl diphosphate + H2O = phyllocladan-16alpha-ol + diphosphate


name: PS is hydrolyzed to 1-acyl LPS by PLA2[15] (Drosophila melanogaster)


name: 3-methylbutanal + NAD(+) + H2O => 3-methylbutanoate + NADH + 2 H(+)


name: IL34 dimer:SDC1 binds CSF1R (Homo sapiens)


name: oxidized [rubredoxin] + H2O2 => reduced [rubredoxin] + superoxide + 2 H(+)


name: ALDH3A2-2 oxidizes pristanal to pristanate (Danio rerio)


name: aldehydo-D-ribose 5-phosphate = D-ribose 5-phosphate


name: tobramycin + carbamoyl adenylate => nebramycin 5' + AMP + H(+)


name: Formation of ORC(2-5) complex (Mus musculus)


name: (3R)-hydroxy-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + NADP(+) => 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + NADPH + H(+)


name: Caspase-mediated cleavage of occludin (Sus scrofa)


name: mRNP complex dissociates from cytosolic face of NPC (Drosophila melanogaster)


name: cytidine(out) + 2 Na(+)(out) = cytidine(in) + 2 Na(+)(in)


name: mogrol + UDP-alpha-D-glucose = mogroside IE + UDP + H(+)


name: Platelet-derived Growth Factor beta Receptor Inhibitors


name: RHOT1 binds effectors at the mitochondrial outer membrane (Dictyostelium discoideum)


name: Secretion of SOD3 (Saccharomyces cerevisiae)


name: quercetin + S-adenosyl-L-methionine <=> rhamnetin + S-adenosyl-L-homocysteine + H(+)


name: AFG3L2 degrades mitochondrial inner membrane proteins (Danio rerio)


name: PKA/PKG phosphorylate Rap1GAP2 (Homo sapiens)


name: CYB5A:heme reduces Asc.- to AscH- (Caenorhabditis elegans)


name: Interaction of SOS with GRB2 bound to FADK1 (Rattus norvegicus)


name: PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane (Sus scrofa)


name: RHOBTB3 binds interacting proteins at trans-Golgi network (Gallus gallus)


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Canis familiaris)


name: glycocholate(out) + n H(+)(out) = glycocholate(in) + n H(+)(in)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Drosophila melanogaster)


name: RUNX3 binds the NOTCH1 coactivator complex (Canis familiaris)


name: LGI1 binds ADAM22 and ADAM23 (Mus musculus)


name: heptyl sulfate + 2-oxoglutarate + O2 <=> heptanal + sulfate + succinate + CO2 + H(+)


name: neurotrophin TRK receptor signaling pathway


name: Interaction of PECAM-1 and SHP-1 (Mus musculus)


name: WIPIs bind PI3P (Drosophila melanogaster)


name: p-Y-STATs dissociate (Rattus norvegicus)


name: FMN(in) + AMP(out) => FMN(out) + AMP(in)


name: N(3)-methylcytidine(32) in tRNA(Ser) + S-adenosyl-L-homocysteine + H(+) => cytidine(32) in tRNA(Ser) + S-adenosyl-L-methionine


name: D-ribose 5-phosphate + ATP => 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) + adenosine 5'-monophosphate (Bos taurus)


name: DVL2 is phosphorylated after WNT5A binding to FZD (Homo sapiens)


name: Sulfhydrylation and ring cleavage of precursor Z (Homo sapiens)


name: SGMS1 transfers phosphocholine onto ceramide (Homo sapiens)


name: RFK:Mg2+ phosphorylates RIB (Canis familiaris)


name: mannitol 2-dehydrogenase (NADP+) activity


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + NAD(+) <=> 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + NADH + H(+)


name: WWTR1 (TAZ), TBX5, and PCAF form a complex (Sus scrofa)


name: SLC7A4 exchanges G6P for Pi across the ER membrane  (Caenorhabditis elegans)


name: inhibition of cytochrome oxidase activity


name: Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1 (Canis familiaris)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine <=> 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine


name: (+)-artemisinate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+) => (+)-artemisinic aldehyde + reduced [NADPH--hemoprotein reductase] + O2


name: cysteine-type endopeptidase activator activity involved in apoptotic process


name: octyl benzoate + CoA => octan-1-ol + benzoyl-CoA


name: biotin + ATP + CoA => biotinyl-CoA + AMP + diphosphate


name: N-acetylation of serotonin (Danio rerio)


name: a (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein] => a 2,3-saturated acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+)


name: STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Mus musculus)


name: L-arginyl-[protein] + methylglyoxal + L-cysteinyl-[protein] = N(5)-[4-(S-L-cysteinyl-[protein])-5-methyl-1H-imidazol-2-yl]-L-ornithinyl-[protein] + 2 H2O + H(+)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Rattus norvegicus)


name: N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol


name: 1-O-methyl-(9Z,12Z)-octadecadienoate + O2 <=> 1-O-methyl-(13S)-hydroperoxy-(9Z,11E)-octadecadienoate


name: ALOX5 binds ALOX5 inhibitors (Bos taurus)


name: D-sedoheptulose 7-phosphate => (R)-demethyl-4-deoxygadusol + phosphate + H2O + H(+)


name: a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GT1a (d18:1(4E)) + CMP + H(+)


name: Caspase-9 binds DCC:DIP13alpha complex (Mus musculus)


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Rattus norvegicus)


name: PP6 dephosphorylates SEC24 (Homo sapiens)


name: Interaction of ISG15 with NEDD4 and inhibition of Ebola virus budding (Bos taurus)


name: ABCA12 transports lipids from cytosol to extracellular region (Canis familiaris)


name: 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine => 2-oxo-3-sulfanylpropanoate + L-kynurenine


name: BIL:ALB scavenges O2.- (Rattus norvegicus)


name: PLK1 hyperphosphorylates Condensin II complex (Plasmodium falciparum)


name: a cytidine in mRNA + S-adenosyl-L-methionine <=> a 5-methylcytidine in mRNA + S-adenosyl-L-homocysteine + H(+)


name: RNF152 polyubiquitinates RRAGA (Dictyostelium discoideum)


name: cadaverine + acetyl-CoA => N-acetylcadaverine + CoA + H(+)


name: protoaustinoid A + A => protoaustinoid B + AH2


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Caenorhabditis elegans)


name: NR1H3 gene transcription regulated by NR1H2,3 (Homo sapiens)


name: acetaldehyde + NAD(+) + CoA <=> acetyl-CoA + NADH + H(+)


name: Change of PKC theta conformation (Canis familiaris)


name: Gamma-carboxy pro-protein S transport from the endoplasmic reticulum to the Golgi apparatus (Canis familiaris)


name: Protein kinase C, alpha type phosphorylates MARCKS (Canis familiaris)


name: Oxidized DNAJA1 binds HSPA1A,B (HSP70) displacing HSF1 (Dictyostelium discoideum)


name: PDCL releases folded G-beta from TRiC/CCT (Xenopus tropicalis)


name: chorismate + NH4(+) => 4-amino-4-deoxychorismate + H2O


name: 3-(carbamoylamino)propanoate + H2O + 2 H(+) => beta-alanine + NH4(+) + CO2


name: RHOQ GAPs stimulate RHOQ GTPase activity (Bos taurus)


name: 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H(+) => 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+)


name: Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Canis familiaris)


name: Cysteine from cystathionine and vice versa (Mycobacterium tuberculosis)


name: (2R)-homocitrate = cis-homoaconitate + H2O


name: 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA => 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA


name: uPAR precursor + acyl-GPI -> uPAR-acyl-GPI + uPAR propeptide (Sus scrofa)


name: DMGLY translocates from cytosol to mitochondrial matrix (Homo sapiens)


name: MET phosphorylates PTK2 (Caenorhabditis elegans)


name: Formation of eIF2:GDP:eIF2B intermediate (Danio rerio)


name: isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Mus musculus)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Canis familiaris)


name: NID1 degradation by MMP19 (Canis familiaris)


name: 3-methyl-2-oxobutanoate + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O = 2-dehydropantoate + (6S)-5,6,7,8-tetrahydrofolate


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate (Xenopus tropicalis)


name: octan-1-ol + hexadecanoyl-CoA => octyl hexadecanoyl + CoA


name: beta-acoradiene + diphosphate => (2E,6E)-farnesyl diphosphate


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Danio rerio)


name: Association of DFF with alpha:beta importin (Sus scrofa)


name: PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Gallus gallus)


name: pyridoxamine 5'-phosphate + pyruvate => pyridoxal 5'-phosphate + L-alanine


name: CARKD dehydrates S-NAD(P)HX to NADPH (Bos taurus)


name: Formation of MSH2:MSH6 Complex (Mus musculus)


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Sus scrofa)


name: Degradation of TGF-beta receptor complex (Mus musculus)


name: PGRMC2:Hemes translocate to the nucleus (Canis familiaris)


name: bromide + formaldehyde + chloride + 2 H(+) => bromochloromethane + H2O


name: pregnan-21-al + NADPH + H(+) => pregnan-21-ol + NADP(+)


name: gardenin B + 2-oxoglutarate + O2 <=> nevadensin + formaldehyde + succinate + CO2 + H(+)


name: pseudopaline + NADP(+) + H2O = (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + 2-oxoglutarate + NADPH + H(+)


name: PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Schizosaccharomyces pombe)


name: IRE1 binds IRE1 forming dimer (Drosophila melanogaster)


name: L-arginine + NADH + O2 + H(+) => N(omega)-hydroxy-L-arginine + NAD(+) + H2O


name: eiF2alpha phosphorylation in response to endoplasmic reticulum stress


name: 9-cis-retinol + NADP(+) => 9-cis-retinal + NADPH + H(+)


name: preechinulin + diphosphate => cyclo(L-tryptophyl-L-alanyl) + dimethylallyl diphosphate


name: [(2->1)-beta-D-fructosyl](n) + sucrose <=> [(2->1)-beta-D-fructosyl](n+1) + D-glucose


name: (11Z)-3-oxoicosenoyl-CoA + NADPH + H(+) => (3R)-hydroxy-(11Z)-eicosenoyl-CoA + NADP(+)


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Gallus gallus)


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)


name: Second strand transfer by annealing complementary PBS sequences (Homo sapiens)


name: CRTAM binds to NECL2 (Rattus norvegicus)


name: dopamine + 3'-phosphoadenylyl sulfate = dopamine 3-O-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Expression of JAG1 during nephron development (Homo sapiens)


name: Beta-catenin recruits CBP/p300 (Bos taurus)


name: melibiose + H2O <=> D-galactose + D-glucose


name: Activation of RAC1 by VAV (Canis familiaris)


name: p-STAT5A, p-STAT5B dissociate from IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:p-STAT5A,p-STAT5B (Bos taurus)


name: daidzein + reduced [NADPH--hemoprotein reductase] + O2 = 2'-hydroxydaidzein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)


name: [thioredoxin]-disulfide + sulfite + adenosine 3',5'-bisphosphate + 2 H(+) => [thioredoxin]-dithiol + 3'-phosphoadenylyl sulfate


name: pyridoxal 5'-phosphate + H2O <=> pyridoxal + phosphate


name: CYP2D6 4-hydroxylates debrisoquine (Dictyostelium discoideum)


name: uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA


name: ISGylation of DDX58 (RIG-I) (Homo sapiens)


name: PI3P is dephosphorylated to PI by MTM proteins at the late endosome membrane (Canis familiaris)


name: L-serine + phosphate => O-phospho-L-serine + H2O


name: heptadecanoate + hnu + H(+) => hexadecane + CO2


name: (24S)-hydroxycholesterol 3-sulfate + adenosine 3',5'-bisphosphate + H(+) => (24S)-hydroxycholesterol + 3'-phosphoadenylyl sulfate


name: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> caffeine + S-adenosyl-L-homocysteine + H(+)


name: Ubiquitination of stimulated EGFR (CBL) (Danio rerio)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Caenorhabditis elegans)


name: NAGLU hydrolyses heparan chain(2) (Dictyostelium discoideum)


name: NCOA2(869-1464) binds KAT6A(1-1118) (Danio rerio)


name: 2alpha-hydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => taxusin + reduced [NADPH--hemoprotein reductase] + O2


name: L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)


name: PP2A-B56 dephosphorylates centromeric cohesin (Bos taurus)


name: MECP2 binds GPRIN1 gene promoter (Homo sapiens)


name: an N-(acyl)-sphingosylphosphoethanolamine = an N-(acyl)-sphingosyl-1,3-cyclic phosphate + ethanolamine


name: Phosphorylation of beta and gamma subunits by LYN (Bos taurus)


name: dCMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 5-methyldeoxycytidine 5'-phosphate + 7,8-dihydrofolate


name: a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine => a monoacyl-sn-glycero-3-phosphocholine + a 1,2-diacylglycerol


name: 3-hydroxybenzoate + ATP + NADPH + H(+) <=> 3-hydroxybenzaldehyde + AMP + diphosphate + NADP(+)


name: OSM binds LIFR:JAKs,OSMR:JAKs (Bos taurus)


name: (R)-dihydrolipoamide + NAD(+) => (R)-lipoamide + NADH + H(+)


name: N-(9Z,12Z,15Z)-octadecatrienoylglycine + 2 L-ascorbate + O2 => N-(9Z,12Z,15Z)-octadecatrienoyl-(2S)-hydroxyglycine + 2 monodehydro-L-ascorbate radical + H2O


name: Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3 (Homo sapiens)


name: sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and 6-alpha-D-glucosyltransferase


name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Homo sapiens)


name: L-lysyl(27)-[histone H3] + 2 formaldehyde + 2 succinate + 2 CO2 => N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 2-oxoglutarate + 2 O2


name: hydroxymalonate + (E)-sinapoyl-CoA <=> (E)-sinapoyltartronate + CoA


name: phenylacetyl-AMP + CoA => phenylacetyl-CoA + AMP + H(+)


name: N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-homocysteine + H(+) => N(6),N(6)-dimethyl-L-lysyl(20)-[histone H4] + S-adenosyl-L-methionine


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Sus scrofa)


name: 2'-N-hydroxynocardicin C + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => 2'-N,N-dihydroxynocardicin C + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: guanosine(34) in tRNA(Tyr) + queuine = queuosine(34) in tRNA(Tyr) + guanine


name: proton-transporting ATP synthase activity, rotational mechanism


name: ALDOB tetramer cleaves Fru-1-P to GA and DHAP (Xenopus tropicalis)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane (Danio rerio)


name: tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity


name: Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Sus scrofa)


name: CHRM4 binds CHRM4 antagonists (Mus musculus)


name: JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Bos taurus)


name: (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone B


name: PLK3 phosphorylates TP53 (Rattus norvegicus)


name: Cu(+)(in) + ATP + H2O = Cu(+)(out) + ADP + phosphate + H(+)


name: 3-hydroxy-3-methylhexanoate + L-glutamine => N(2)-(3-hydroxy-3-methylhexanoyl)-L-glutaminate + H2O


name: an N-acylglycine + CoA + H(+) => an acyl-CoA + glycine


name: Stalling of DNA replication fork and RPA binding (Canis familiaris)


name: CYP11A1 cleaves 20a,22b-DHCHOL (Danio rerio)


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Sus scrofa)


name: (E)-coniferyl acetate + NADPH => eugenol + acetate + NADP(+)


name: SCD5 desaturates ST-CoA to OLE-CoA (Dictyostelium discoideum)


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + NAD(+) <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADH


name: Type II receptor phosphorylates type I receptor (Canis familiaris)


name: N-acetyl-D-glucosamine 6-phosphate => aldehydo-N-acetyl-D-mannosamine 6-phosphate


name: HIF-alpha binds ARNT (HIF1-beta) forming HIF-alpha:ARNT (Bos taurus)


name: ERBB4 binds WWP1/ITCH ubiquitin ligases (Homo sapiens)


name: (E)-beta-farnesene + diphosphate => (2E,6E)-farnesyl diphosphate


name: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoate + H(+)


name: 4,4-dimethyl-8,14-cholestadien-3beta-ol + NADPH + H(+) => 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + NADP(+)


name: PP5 dephosphorylates RAF1 S338 (Bos taurus)


name: p-ERK phosphorylates WAVEs and ABI (Bos taurus)


name: SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Dictyostelium discoideum)


name: 2-methoxy-6-(all-trans-decaprenyl)phenol + CO2 => 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoate + H(+)


name: PDSS1,2 ligates FPP to IPPP (Rattus norvegicus)


name: coenzyme F430 + ADP + phosphate => 15,17(3)-seco-F430-17(3)-acid + ATP


name: PAK1 phosphorylates LIMK1 (Gallus gallus)


name: RHOF binds effectors at the plasma membrane (Danio rerio)


name: B-WICH recruits histone acetyltransferases (Mus musculus)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Sus scrofa)


name: Fibronectin degradation by MMP1, 3, 7, 12, 13, 19, CTSS (Xenopus tropicalis)


name: maltotriose + H2O => maltose + D-glucose (sucrase-isomaltase) (Sus scrofa)


name: PPM1K dephosphorylates p-BCKDH (Homo sapiens)


name: p-MAPK2/3 phosphorylates HSP27 (Sus scrofa)


name: MRN activates ATM (Saccharomyces cerevisiae)


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Canis familiaris)


name: Ethylene is oxidized to Ethylene oxide by CYP1A1 (Homo sapiens)


name: CBLIF binds RCbl (Drosophila melanogaster)


name: HLCS biotinylates ACACB (Drosophila melanogaster)


name: CBR3 reduces DOX to DOXOL (Rattus norvegicus)


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Plasmodium falciparum)


name: Activated type I receptor phosphorylates R-Smad1/5/8 directly (Bos taurus)


name: 15-deoxy-Delta(12,14)-prostaglandin J2 + glutathione = 15-deoxy-Delta(12,14)-prostaglandin J2-S-(R)-glutathione


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Danio rerio)


name: BRCA1 forms a heterodimer with BARD1 (Sus scrofa)


name: a 2'-deoxyguanosine in DNA + methylglyoxal => an N(2)-(1-hydroxy-2-oxopropyl)-2'-deoxyguanosine in DNA


name: G alpha (12) binds BTK (Canis familiaris)


name: a medium-chain (2E)-enoyl-CoA + H2O2 => a medium-chain 2,3-saturated fatty acyl-CoA + O2


name: factor X -> factor Xa + factor X activation peptide (TF:F7 catalyst) (Canis familiaris)


name: SPOP:CUL3:RBX1 ubiquitinates GLI2,3 (Gallus gallus)


name: RAB13 GEFs exchange GTP for GDP on RAB13 (Bos taurus)


name: Translocation of PMAIP1 (NOXA) to mitochondria (Gallus gallus)


name: ACSF3 ligates CoA-SH to VLCFA (Bos taurus)


name: N(omega)-hydroxy-L-arginine + NAD(+) + H2O => L-arginine + NADH + O2 + H(+)


name: Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Homo sapiens)


name: an N-acylethanolamine + H2O <=> ethanolamine + a fatty acid


name: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate <=> D-erythrose 4-phosphate + D-fructose 6-phosphate (Caenorhabditis elegans)


name: 5beta-pregnan-3,20-dione + NADPH + H(+) => 3beta-hydroxy-5beta-pregnane-20-one + NADP(+)


name: Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA (Caenorhabditis elegans)


name: 11-hydroxy-(9Z,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2


name: 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine


name: Doubly neddylated UBA3:NAE1 binds AcM-UBE2F (Bos taurus)


name: HLA-A specific activating MHC class I receptor activity


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Canis familiaris)


name: PI3K alpha, beta, gamma convert PIP2 to PIP3 (Xenopus tropicalis)


name: activation of tissue kallikrein-kinin cascade


name: SMURF1/2 are recruited to the DVL2:PARD6A complex (Canis familiaris)


name: alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose => alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose


name: metalloendoprotease activity involved in APP catabolic process


name: positive regulation of cholesterol transport


name: CDH11 forms heterotypic trans dimer with CDH24 (Homo sapiens)


name: Autocatalytic phosphorylation of FGFR3 cysteine mutants (Homo sapiens)


name: BCL2L11 gene expression is stimulated by FOXO1,FOXO3,(FOXO4) and NF-Y (Homo sapiens)


name: N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Bos taurus)


name: cholesterol + reduced [NADPH--hemoprotein reductase] + O2 => (22R)-hydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: A4GALT transfers galactose to LacCer (Mus musculus)


name: EP300 acetylates histone H2A, H2B, H3, H4 (Bos taurus)


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Xenopus tropicalis)


name: D-cysteine + H2O => hydrogen sulfide + pyruvate + NH4(+) + H(+)


name: L-thyroxine(out) + L-glutamate(in) => L-thyroxine(in) + L-glutamate(out)


name: Increased Muscular System Gastrin Activity


name: PHF8 demethylates MeK21-histone H4 (Mus musculus)


name: Activated human JNKs migrate to nucleoplasm (Mus musculus)


name: E1 mediated ubiquitin activation (Danio rerio)


name: maltotriose + H2O => maltose + D-glucose (maltase-glucoamylase) (Gallus gallus)


name: sphing-4-enine 1-phosphate(in) <=> sphing-4-enine 1-phosphate(out)


name: [phosphatase 2A protein]-C-terminal L-leucine methyl ester + H2O = [phosphatase 2A protein]-C-terminal L-leucine + methanol + H(+)


name: marinolate C + ATP + CoA = marinoloyl-CoA C + AMP + diphosphate


name: Phosphorylation of Cyclin E:CDK2 complexes by WEE1 (Mus musculus)


name: oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT1] (Drosophila melanogaster)


name: cyclohexane-1-carbonyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) => cyclohex-1-ene-1-carbonyl-CoA + reduced [electron-transfer flavoprotein]


name: POLZ extends translesion synthesis (Gallus gallus)


name: HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Homo sapiens)


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + acetyl-CoA => 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: Interaction of DAP12 and KIR2DS4 (Homo sapiens)


name: activation of ubiquitin protein ligase activity


name: Expression of 7-Dehydrocholesterol Reductase (DHCR7) (Homo sapiens)


name: a ganglioside GT1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1c (d18:1(4E)) + CMP + H(+)


name: Decreased Striated Muscle Substance P Activity


name: (indol-3-yl)acetate(out) + a dicarboxylate(in) <=> (indol-3-yl)acetate(in) + a dicarboxylate(out)


name: syringetin + S-adenosyl-L-methionine => 3,3',5'-O-trimethylmyricetin + S-adenosyl-L-homocysteine + H(+)


name: TP53BP1 recruits DCLRE1C to ATM (Gallus gallus)


name: [CysO sulfur-carrier protein]-Gly-NH-CH2-C(O)-S-L-Cys + H2O = [CysO sulfur-carrier protein]-C-terminal Gly-Gly + L-cysteine + H(+)


name: "[CysO sulfur-carrier protein]-S-L-cysteine hydrolase"


name: (3R,6R)-6-hydroxy-3-isopropenylheptanoate + H(+) => (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + H2O


name: a very long-chain fatty acyl-CoA + a sphingoid base <=> an N-(very-long-chain fatty acyl)-sphingoid base + CoA + H(+)


name: Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Mus musculus)


name: lactate + H+ [cytosol] <=> lactate + H+ [extracellular] (Gallus gallus)


name: Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA (Homo sapiens)


name: TTPA transports alpha-TOH from lysosomal membrane to plasma membrane (Mus musculus)


name: 5,6-EET is hydrolysed to 5,6-DHET by EPHX2 (Plasmodium falciparum)


name: pyridoxamine + ATP <=> pyridoxamine 5'-phosphate + ADP + H(+)


name: [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity


name: 2-chloro-4-nitrotoluene + NADH + O2 => 3-chloro-4-methylcatechol + nitrite + NAD(+)


name: Nuclear PHD1,3 hydroxylates proline residues on HIF3A (Xenopus tropicalis)


name: BET translocates from mitochondrial matrix to cytosol (Homo sapiens)


name: Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Homo sapiens)


name: Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)


name: 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD(+) <=> 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H(+)


name: 2-aminopentan-1-ol + NAD(+) + H2O => 1-hydroxypentan-2-one + NH4(+) + NADH + H(+)


name: UROD decarboxylates URO3 to COPRO3 (Bos taurus)


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde <=> quinolinate + H2O + H(+)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Caenorhabditis elegans)


name: Gq activation by TP receptor (Danio rerio)


name: Translocation of PMAIP1 (NOXA) to mitochondria (Homo sapiens)


name: hydroxymalonate + (E)-sinapoyl-CoA = (E)-sinapoyltartronate + CoA


name: ADRB2:Catecholamine binds ARRB1, ARRB2 (Canis familiaris)


name: ubiquinol-10 + NAD(+) => ubiquinone-10 + NADH + H(+)


name: TAT deaminates tyrosine (Drosophila melanogaster)


name: 2-methyl-3-oxobutanoyl-CoA + NADH + H(+) => (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+)


name: (9Z,12Z,15Z)-octadecatrienamide + H2O = (9Z,12Z,15Z)-octadecatrienoate + NH4(+)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Canis familiaris)


name: progesterone + reduced [NADPH--hemoprotein reductase] + O2 => 6beta-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: ABCB1 transports PREDN,PREDL out of kidney cells (Homo sapiens)


name: L-tyrosinal + AMP + diphosphate + NADP(+) => L-tyrosine + ATP + NADPH + H(+)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Canis familiaris)


name: D-ribose 5-phosphate + uracil <=> psi-UMP + H2O


name: DCC interaction with Netrin-1 (Danio rerio)


name: prostaglandin F2alpha + NADP(+) = 15-oxoprostaglandin F2alpha + NADPH + H(+)


name: tert-butyl hydroperoxide + [thioredoxin]-dithiol <=> tert-butanol + [thioredoxin]-disulfide + H2O


name: stimulation of fibroblast growth factor receptor signaling pathway


name: extrinsic apoptotic signaling pathway in presence of ligand


name: L-leucine(out) + L-aspartate(in) => L-leucine(in) + L-aspartate(out)


name: 3 hydrogencarbonate(in) + Na(+)(in) => 3 hydrogencarbonate(out) + Na(+)(out)


name: Trans-autophosphorylation of ERBB4 homodimers (Canis familiaris)


name: 5-fluorouridine + ATP = 5-fluorouridine 5'-phosphate + ADP + H(+)


name: ZFP36L2 binds CNOT6L of CCR4-CNOT complex and an AU-rich element in mRNA (Homo sapiens)


name: a 3-(omega-methylsulfanyl)alkylmalate => a 2-(omega-methylsulfanyl)alkylmaleate + H2O


name: N-acetyl-S-benzyl-L-cysteine + FMNH2 + O2 <=> (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMN + H2O + H(+)


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Xenopus tropicalis)


name: 6-tuliposide B = tulipalin B + D-glucose


name: PTGS1,2 dimers bind PTGS Inhibitors (Homo sapiens)


name: a 12-hydroxyjasmonyl-L-alpha-amino acid + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 <=> a 12-hydroxy-12-oxojasmonyl-L-alpha-amino acid + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 3 H(+)


name: TIMM9:TIMM10 transfers proteins to TIMM22 (Homo sapiens)


name: KAT2B,EP300 acetylate FOXO3 under oxidative stress (Mus musculus)


name: Two NPFF receptors can bind neuropeptide FF (Sus scrofa)


name: uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Mus musculus)


name: Carbonic anhydrase hydrates carbon dioxide (mitochondria) (Danio rerio)


name: O-nonanoyl-L-seryl-[protein] + CoA => nonanoyl-CoA + L-seryl-[protein]


name: Surface deployment of platelet alpha granule membrane components (Schizosaccharomyces pombe)


name: NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras (Drosophila melanogaster)


name: AMP + phosphate <=> alpha-D-ribose 1,5-bisphosphate + adenine


name: Autocatalytic activation of proMMP2 (Xenopus tropicalis)


name: L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(27)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: cyclo(L-arginyl-(Z)-dehydro-3,4-dihydroxytyrosyl) + O-acetyl-L-homoserine <=> cyclo(L-arginyl-(Z)-dehydro-4-O-homoseryl-tyrosyl) + acetate + H(+)


name: DL/DIF dimer binds to TUB and phosphorylated PLL in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)


name: (2E)-tetradecenedioyl-CoA + H2O2 => tetradecanedioyl-CoA + O2


name: SMOX-3 oxidises SPN to SPM (Xenopus tropicalis)


name: 1-octadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + H2O => 1-octadecanoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)


name: ADPRHL2 hydrolyses poly(ADP-ribose) (Sus scrofa)


name: Ubiquitinated RNF41 binds P-USP8 (Gallus gallus)


name: L-galactonate => 2-dehydro-3-deoxy-L-galactonate + H2O


name: (2E)-decenoyl-CoA + NADP(+) = (2E,4Z)-decadienoyl-CoA + NADPH + H(+)


name: KSRP recruits RNA degradation activities (Homo sapiens)


name: eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate => 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA


name: activation of glucocorticoid catabolic process


name: apo-Transferrin dissociates from the receptor complex (Mus musculus)


name: thymidine or deoxyuridine + orthophosphate <=> thymine or uracil + 2-deoxy-D-ribose 1-phosphate [TYMP] (Mus musculus)


name: ADP + phosphate + 5 H(+)(out) => ATP + H2O + 4 H(+)(in)


name: malonyl-[ACP] + S-adenosyl-L-methionine <=> malonyl-[ACP] methyl ester + S-adenosyl-L-homocysteine


name: N(6)-dimethylallyladenine + S-adenosyl-L-methionine => discadenine + S-methyl-5'-thioadenosine + H(+)


name: SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Homo sapiens)


name: acetyl phosphate + sulfite + H(+) => sulfoacetaldehyde + phosphate


name: an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)


name: Transfer of electrons through the succinate dehydrogenase complex (Homo sapiens)


name: GLI3R binds the PTCH1 promoter (Homo sapiens)


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Rattus norvegicus)


name: prostaglandin F2alpha(out) + 2 (S)-lactate(in) = prostaglandin F2alpha(in) + 2 (S)-lactate(out)


name: DLD dimer dehydrogenates dihydrolipoyl (Caenorhabditis elegans)


name: GTSE1 binds microtubule lattice in interphase cells (Xenopus tropicalis)


name: benzoate + ATP + NADPH + H(+) = benzaldehyde + AMP + diphosphate + NADP(+)


name: PDE6 hydrolyses cGMP to GMP (Homo sapiens)


name: GABR heteropentamers:GABA transport Cl- from extracellular region to cytosol (Gallus gallus)


name: positive regulation of glucagon-like peptide receptor 1 activity in another organism


name: alpha-Kdo-(2->6)-lipid IVA (E. coli) + ATP => 4-O-phospho-alpha-Kdo-(2->6)-lipid IVA (E. coli) + ADP + H(+)


name: MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Canis familiaris)


name: GALNT3 transfers GalNAc to FGF23 (Drosophila melanogaster)


name: an N-acyl-D-amino acid + H2O => a D-alpha-amino acid + a carboxylate


name: D-methylmalonyl-CoA <=> L-methylmalonyl-CoA (Homo sapiens)


name: p-STAT3 dissociates from IL20:IL20RA:JAK1:IL20RB:p-Y1007,Y1008-JAK2,p-JAK3 (Gallus gallus)


name: SLC26A11 transports SO4(2-) from extracellular region to cytosol (Dictyostelium discoideum)


name: Association of LBP with LPS (Mus musculus)


name: [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n) + n D-aspartate + n ATP = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + n ADP + n phosphate + n H(+)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Canis familiaris)


name: meso-2,6-diaminoheptanedioate + H(+) = L-lysine + CO2


name: beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP-alpha-D-galactofuranose = [beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->6)]14-beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnopyranosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + 28 UDP + 28 H(+)


name: BACE1(46-501) translocates from Golgi lumen to plasma membrane (Homo sapiens)


name: 4-phospho-D-erythronate + NAD(+) = dihydroxyacetone phosphate + CO2 + NADH


name: a wax ester + H2O = a long chain fatty alcohol + a long-chain fatty acid + H(+)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + L-serine + H(+)


name: 2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)


name: dihydrosanguinarine + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxydihydrosanguinarine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Reduction of 2-trans-4-cis-decadienoyl-CoA to form 3-trans-decenoyl-CoA (Bos taurus)


name: Abortive termination of elongation after arrest (Homo sapiens)


name: RHOG binds effectors at the plasma membrane (Xenopus tropicalis)


name: Transport of MHC II:Ii complex to plasma membrane (Rattus norvegicus)


name: NLK mRNA translation controlled by miR-92b (Homo sapiens)


name: histo-blood group P(k) UDP-galactose activity


name: D-xylobiose + O2 => D-xylobiono-1,5-lactone + H2O2


name: PGH2 is reduced to PGF2a by AKR1C3 (Saccharomyces cerevisiae)


name: 3-(3-methylsulfanyl)propylmalate <=> 2-(2-methylsulfanyl)propylmaleate + H2O


name: (3S)-3-hydroxyadipyl-CoA => (E)-2,3-didehydroadipoyl-CoA + H2O


name: (2R,9Z)-2-hydroperoxyoctadecenoate => (9Z)-octadecenoate + O2


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA <=> 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA


name: Elastin degradation by MMP14 (Rattus norvegicus)


name: D-sorbitol + NADP(+) => D-glucose + NADPH + H(+)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Bos taurus)


name: holo-[peptidyl-carrier protein] + L-alanine + ATP => L-alanyl-[peptidyl-carrier protein] + AMP + diphosphate


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Mus musculus)


name: C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Canis familiaris)


name: CD28 bound PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: succinate-CoA ligase (ADP-forming) activity


name: apoTF:TFRC dimer translocates from endosome membrane to plasma membrane (Bos taurus)


name: abacavir monophosphate + H2O => carbovir monophosphate + cyclopropylamine (Mus musculus)


name: 2 (3R)-3-isocyanylbutanoyl-[ACP] + L-lysine + ATP + 2 NADPH <=> (2S)-2,6-bis[(3R)-3-isocyanobutanamido]hexan-1-ol + 2 holo-[ACP] + AMP + diphosphate + 2 NADP(+)


name: a 1,2-diacyl-sn-glycerol + UDP-alpha-D-glucose => a 1,2-diacyl-3-O-(beta-D-glucopyranosyl)-sn-glycerol + UDP + H(+)


name: PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Xenopus tropicalis)


name: cytidine(out) + 2 Na(+)(out) <=> cytidine(in) + 2 Na(+)(in)


name: a neolactoside IV(3)-alpha-NeuNAc,III(3)-alpha-Fuc-nLc4Cer(d18:1(4E)) + GDP + H(+) => a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + GDP-beta-L-fucose


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoyl-CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA


name: HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Sus scrofa)


name: Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Rattus norvegicus)


name: N-(2-hydroxytetracosanoyl)-(4R)-hydroxysphinganine + NADP(+) + H2O => N-tetracosanoyl-(4R)-hydroxysphinganine + NADPH + O2 + H(+)


name: SFTPB dimer,C translocate from multivesicle body to lamellar body (Gallus gallus)


name: prostaglandin F2alpha(out) + glutarate(in) => prostaglandin F2alpha(in) + glutarate(out)


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Xenopus tropicalis)


name: 1-octadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + H2O => hexanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: eburicol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 <=> 14-demethyleburicol + formate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Caenorhabditis elegans)


name: positive regulation of sarcinapterin biosynthetic process


name: docosanoyl-CoA + acetyl-CoA => 3-oxotetracosanoyl-CoA + CoA


name: L-histidine + S-adenosyl-L-methionine = (2S)-2-amino-4-{[(1S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + S-methyl-5'-thioadenosine + H(+)


name: 3,4-dihydroxybenzoate + NADH + 2 H(+) => 3,4-dihydroxybenzaldehyde + NAD(+) + H2O


name: AcK-NFE2L2 binds the AREG gene (Homo sapiens)


name: (+)-copalyl diphosphate = abieta-7,13-diene + diphosphate


name: 5-methylcytidine(40) in tRNA precursor + S-adenosyl-L-homocysteine + H(+) => cytidine(40) in tRNA precursor + S-adenosyl-L-methionine


name: dTDP-beta-L-vancosamine + devancoaminyl-vancomycin => vancomycin + dTDP + H(+)


name: Hemoglobin:Haptoglobin:CD163 is endocytosed (Danio rerio)


name: RAB3IP and RAB8A bind to the ciliary targeting complex (Caenorhabditis elegans)


name: cyathin A3 + acetyl-CoA = 11-O-acetylcyathin A3 + CoA


name: 2-oxopentanoate + L-kynurenine = L-2-aminopentanoate + kynurenate + H2O


name: D-gluconate + ATP => 6-phospho-D-gluconate + ADP + H(+)


name: 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA) (Sus scrofa)


name: nucleobase:monoatomic cation symporter activity


name: VEGFA-165 dimer binds VEGFR2 dimer (Homo sapiens)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Dictyostelium discoideum)


name: MOBP gene expression is inhibited by MECP2 (Homo sapiens)


name: cellulose catabolism by endo-processive cellulases


name: Ubiquitinated AXIN is degraded by the proteasome (Canis familiaris)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + ATP


name: NSF and SNAPs bind the cis-SNARE at the Golgi (Mus musculus)


name: 1-hexadecanoyl-2-(9Z)-octadecenoyl-3-octadecanoyl-sn-glycerol + H2O <=> 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + octadecanoate + H(+)


name: CARM1 methylates arginine-27 of histone H3 (H3R26) (Bos taurus)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Xenopus tropicalis)


name: KDM1A, KDM1B demethylate Me2K5-histone H3 (Rattus norvegicus)


name: (R)-4'-phosphopantetheine sulfonate + H2O <=> (R)-pantetheine sulfonate + phosphate


name: D-glycero-alpha-D-manno-heptose 1,7-bisphosphate + H2O = D-glycero-alpha-D-manno-heptose 1-phosphate + phosphate


name: GSTs transfer GSH to NAPQI to form APAP-SG (Dictyostelium discoideum)


name: 5-aminomethyl-dUMP in DNA + acetyl-CoA = 5-acetylaminomethyl-dUMP in DNA + CoA + H(+)


name: (7R,8S)-7,8-diammoniononanoate + CO2 => (7R,8S)-8-amino-7-(carboxyamino)nonanoate + 2 H(+)


name: Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9) (Bos taurus)


name: KIF7 is recruited to the ciliary tip through interaction with axonemal microtubules (Dictyostelium discoideum)


name: a 5'-end triphospho-(purine-ribonucleoside) in mRNA + GDP + H(+) = a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + diphosphate


name: Phosphorylation of Cdc25A at Ser-123 by Chk1 (Sus scrofa)


name: N(1)-acetylspermine + H2O = spermine + acetate


name: positive regulation of L-glutamate import


name: carbamoyl phosphate + ornithine => citrulline + orthophosphate (Bos taurus)


name: (2E)-hexadecenoyl-CoA + H2O => (3R)-hydroxyhexadecanoyl-CoA


name: 5-carboxy-1-(5-O-phospho-beta-D-ribofuranosyl)pyridinium-3-carbonyl adenylate + [LarE protein]-L-cysteine <=> [LarE protein]-S-[5-carboxy-1-(5-O-phosphono-beta-D-ribofuranosyl)pyridinium-3-carbonyl]-L-cysteine + AMP + H(+)


name: Beta-defensins 4A and 103 bind CCR2 (Canis familiaris)


name: L-isoleucine(in) + Na(+)(in) <=> L-isoleucine(out) + Na(+)(out)


name: SLC9B1/C2 exchange Na+ for H+ (Bos taurus)


name: umbelliferone + dimethylallyl diphosphate = demethylsuberosin + diphosphate


name: COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex (Bos taurus)


name: FH tetramer hydrates fumarate to L-malate (Bos taurus)


name: (3S)-hydroxyoctadecanoyl-CoA <=> (2E)-octadecenoyl-CoA + H2O


name: L-threonyl-[rhodopsin] + ATP = O-phospho-L-threonyl-[rhodopsin] + ADP + H(+)


name: (3S)-hydroxydecanedioyl-CoA + NAD(+) => 3-oxodecanedioyl-CoA + NADH + H(+)


name: CDC42 GEFs activate CDC42 (Dictyostelium discoideum)


name: PHLPP dephosphorylates S473 in AKT (Mus musculus)


name: Autophosphorylation of ALK fusions (Homo sapiens)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Bos taurus)


name: AKT phosphorylates MKRN1 (Dictyostelium discoideum)


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O => (-)-geosmin + acetone


name: trehalose transmembrane transporter activity


name: (3R)-hydroxy-(11Z)-eicosenoyl-CoA => (2E,11Z)-eicosadienoyl-CoA + H2O


name: an all-trans-retinyl ester + CoA => all-trans-retinol + an acyl-CoA


name: rebaudioside A + UDP-alpha-D-glucose <=> rebaudioside D + UDP + H(+)


name: mitochondrial light strand promoter sense binding


name: PIAS3 SUMOylates MITF with SUMO1 (Caenorhabditis elegans)


name: LTC4 is exported from the cytosol by ABCC1 (Dictyostelium discoideum)


name: F-actin capping protein is a heterodimer (Dictyostelium discoideum)


name: Active LTK receptor phosphorylates SHC1 (Mus musculus)


name: N-methylhexanamide + H2O => hexanoate + methylamine


name: (2E,16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontaheptaenoyl-CoA + NADPH + H(+) => (16Z,19Z,22Z,25Z,28Z,31Z)-tetratriacontahexaenoyl-CoA + NADP(+)


name: AUF1 binds translation and heat shock proteins (Bos taurus)


name: I(1,3,4,6)P4 is dephosphorylated to I(1,3,4)P3 by ITPK1 in the cytosol (Dictyostelium discoideum)


name: (2S)-2-amino-3-methylbutan-1-ol + NAD(+) + H2O => 1-hydroxy-3-methylbutan-2-one + NH4(+) + NADH + H(+)


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Drosophila melanogaster)


name: (9Z)-octadecenoate + O2 = (8R)-hydroperoxy-(9Z)-octadecenoate


name: a 2-acyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + a fatty acid + H(+)


name: Rb(+)(in) + 2 hydrogencarbonate(in) + chloride(out) = Rb(+)(out) + 2 hydrogencarbonate(out) + chloride(in)


name: adenosine + 2 O2 + H2O => 9-riburonosyladenine + 2 H2O2 + H(+)


name: Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2) (Rattus norvegicus)


name: bradykinin + H2O => L-Phe-L-Arg + bradykinin(1-7)


name: oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor


name: "With an iron-sulfur protein as acceptor"


name: resolvin D2 + NAD(+) => 16-oxoresolvin D2 + NADH + H(+)


name: Activated MAPK phosphorylates RAF1 (Gallus gallus)


name: glycochenodeoxycholate(in) + glutathione(in) + ATP + H2O = glycochenodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)


name: itaconate + glutaryl-CoA => itaconyl-CoA + glutarate


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Plasmodium falciparum)


name: Export of peptide loaded MHC class I complex to PM (Rattus norvegicus)


name: VAV2 is a GEF for Rho/Rac family kinases (Homo sapiens)


name: an N-acyl-1-beta-D-glucosyl-15-methylhexadecasphing-4-enine + H2O => an N-acyl-15-methylhexadecasphing-4-enine + D-glucose


name: Cholest-5-ene-3beta,7alpha,24(S)-triol is oxidized and isomerized to 4-cholesten-7alpha,24(S)-diol-3-one (Rattus norvegicus)


name: 1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate <=> 5-phospho-alpha-D-ribose 1-diphosphate + ATP


name: 11-deoxycortisol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = cortisol + 2 oxidized [adrenodoxin] + H2O


name: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O


name: Defective DHDDS does not elongate E,E-FPP (Homo sapiens)


name: trans,octa-cis-decaprenyl phosphate + 5-phospho-alpha-D-ribose 1-diphosphate + H(+) => trans,octa-cis-decaprenylphospho-beta-D-ribofuranose 5-phosphate + diphosphate


name: testosterone + reduced [NADPH--hemoprotein reductase] + O2 <=> 6beta,17beta-dihydroxyandrost-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: S-(1-hydroxy-2-oxoethyl)-L-cysteinyl-[protein] + H2O = glycolate + L-cysteinyl-[protein] + H(+)


name: apigenin 7-O-(6-O-malonyl-beta-D-glucoside) + CoA => apigenin 7-O-beta-D-glucoside + malonyl-CoA


name: N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate => 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (7,8-dihydropterin-6-yl)methyl diphosphate


name: ADP + ADP <=> AMP + ATP [AK2] (Bos taurus)


name: Activated FGFR4 phosphorylates PPTN11 (Sus scrofa)


name: P-type transmembrane transporter activity


name: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADPH + O2 + H(+) <=> 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP(+) + H2O


name: (S)-3-hydroxyglutaryl-CoA <=> (2E)-glutaconyl-CoA + H2O


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Dictyostelium discoideum)


name: down regulation of copper electron carrier


name: FUT3,5,6,7 transfers Fuc to Type 2 MSGG to form sLeX (Canis familiaris)


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Schizosaccharomyces pombe)


name: L-homoarginine(in) + L-ornithine(out) = L-homoarginine(out) + L-ornithine(in)


name: biphenyl-2,2',3-triol + NADH + O2 + H(+) <=> biphenyl-2,2',3,3'-tetraol + NAD(+) + H2O


name: PPM1D dephosphorylates RUNX2 (Mus musculus)


name: RHOQ binds effectors at the plasma membrane (Dictyostelium discoideum)


name: p-IRF7:p-IRF7 translocates to the nucleus (Sus scrofa)


name: glutaryl-CoA + A = (2E)-glutaconyl-CoA + AH2


name: IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Rattus norvegicus)


name: Cleavage of Procaspase-7 by the apoptosome (Rattus norvegicus)


name: SLC22A13 transports NCA from extracellular region to cytosol (Drosophila melanogaster)


name: factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst) (Sus scrofa)


name: Free APC/C phosphorylated by Cyclin B:Cdc2 (Sus scrofa)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Bos taurus)


name: HSF1 trimer translocates to the nucleus (Saccharomyces cerevisiae)


name: Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Dictyostelium discoideum)


name: ROS,RNS oxidize ACO2:4Fe-4S (Caenorhabditis elegans)


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Danio rerio)


name: positive regulation of estrone UDPglucuronosyltransferase activity


name: CBX4 SUMOylates BMI1 in PRC1 with SUMO1 (Bos taurus)


name: 2-methyl-1,3,5-trinitrocyclohex-2-en-1-ide + NADP(+) => 4-methyl-1,3,5-trinitrocyclohexa-2,4-dien-1-ide + NADPH + H(+)


name: Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex (Dictyostelium discoideum)


name: ent-kaur-16-ene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 => ent-kaur-16-en-19-oate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: ACLY tetramer transforms CIT to Ac-CoA (Bos taurus)


name: positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway


name: ecgonine methyl ester + benzoyl-CoA => cocaine + CoA


name: (3S)-hydroxy-(5Z-tetradecenoyl)-CoA => (2E,5Z)-tetradecadienoyl-CoA + H2O


name: SERINC3,5,(1,2,4) transport L-Ser from cytosol to plasma membrane (Sus scrofa)


name: melibiose(in) + H(+)(in) = melibiose(out) + H(+)(out)


name: TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Xenopus tropicalis)


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Drosophila melanogaster)


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol => (1S,4aS)-1,4a-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalene + acetone


name: transmembrane receptor protein serine/threonine kinase ligand binding


name: 4-acetoxyphenol + H2O <=> hydroquinone + acetate + H(+)


name: Translocation of active Cdc25C to the nucleus (Dictyostelium discoideum)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Canis familiaris)


name: 9-cis-10'-apo-beta-carotenal cleavage oxygenase activity


name: (S)-2-amino-6-oxohexanoate + NH4(+) + NADH + H(+) => L-lysine + NAD(+) + H2O


name: ladanein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => apigenin 4',7-dimethyl ether + reduced [NADPH--hemoprotein reductase] + O2


name: lactate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+) <=> 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate + 2 NADH


name: SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Sus scrofa)


name: NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Canis familiaris)


name: NAPRT1 dimer transfers PRIB to NCA to form NAMN (Plasmodium falciparum)


name: 7,8-dihydrofolate + dTMP => dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate


name: Transfer of LPS onto TLR4 (Mus musculus)


name: COQ2 ligates all-E-10PrP2 to PHB (Dictyostelium discoideum)


name: Ubiquitinated geminin is degraded by the proteasome (Homo sapiens)


name: a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-homocysteine + H(+) => a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + S-adenosyl-L-methionine


name: [(3R)-hydroxybutanoate](n) + H2O <=> [(3R)-hydroxybutanoate](n-1) + (R)-3-hydroxybutanoate + H(+)


name: ST8SIA1-6 transfer Neu5Ac to terminal Neu5Ac residues (Bos taurus)


name: methyl tertiary butyl ether 3-monooxygenase activity


name: N,N-dimethylglycine(out) + Na(+)(out) <=> N,N-dimethylglycine(in) + Na(+)(in)


name: p-PKR dimer phosphorylates SNCA (Mus musculus)


name: NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP (Bos taurus)


name: Maturation of the preholospermatoproteasome (Homo sapiens)


name: 2-oxoheptanedioate + acetyl-CoA + H2O <=> (R)-trihomocitrate + CoA + H(+)


name: an alpha-D-mannosylinositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = an inositol-1-phospho-D-mannosyl-alpha-1->6-inositol-1-phospho-N-(2-hydroxyacyl)-4R-hydroxysphingoid base + a 1,2-diacyl-sn-glycerol


name: (E)-4-coumaraldehyde + NADP(+) + CoA => (E)-4-coumaroyl-CoA + NADPH + H(+)


name: Ubiquitinated Orc1 is degraded by the proteasome (Canis familiaris)


name: p190RhoGAP binds Plexin-B1 (Rattus norvegicus)


name: a di-trans,poly-cis-dolichol + NAD(+) => a di-trans,poly-cis-dolichal + NADH + H(+)


name: (17Z,20Z,23Z,26Z)-dotriacontatetraenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(19Z,22Z,25Z,28Z)-tetratriacontatetraenoyl-CoA + CO2 + CoA


name: AWAT2 transfers PALM from PALM-CoA to atROL, forming atR-PALM (Homo sapiens)


name: p-Y705-STAT3 dimer translocates from cytosol to nucleoplasm (Homo sapiens)


name: N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + H2O = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein]


name: SUMOylation of HIPK2 with SUMO1 (Caenorhabditis elegans)


name: RNF34 or RFFL ubiquitinates phosphorylated TP53 (Drosophila melanogaster)


name: DRD2 antagonist drugs bind to DRD2 (Sus scrofa)


name: CBCAP complex binds 7-methylguanosine cap of snRNA (Drosophila melanogaster)


name: 1-deoxy-D-xylulose 5-phosphate + methanethiol + A => S-methyl-1-thio-D-xylulose 5-phosphate + AH2


name: SL (surrogate light chain) binds IgH to form pre-BCR (Rattus norvegicus)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Homo sapiens)


name: (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)


name: Recruitment of POLB to the AP site (Homo sapiens)


name: Phosphorylated SHC1 recruits SHIP (Rattus norvegicus)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA => 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA


name: thiamine triphosphate phosphatase activity


name: AKT3 phosphorylates TBX3 (Rattus norvegicus)


name: D-arabinose + NADP(+) <=> D-arabinono-1,5-lactone + NADPH + H(+)


name: (2E,6E)-farnesyl diphosphate = guaia-4,6-diene + diphosphate


name: VAV3 is a GEF for Rho/Rac family kinases (Canis familiaris)


name: 2-methyl-3-oxopropanoate + L-glutamate => (S)-3-amino-2-methylpropanoate + 2-oxoglutarate


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Mus musculus)


name: ATM dimer:PEX5 phosphorylates PEX5 (Canis familiaris)


name: Increased Spinal Cord Serotonin Activity


name: Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Homo sapiens)


name: alpha,alpha-trehalose(out) + ATP + H2O = alpha,alpha-trehalose(in) + ADP + phosphate + H(+)


name: Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Sus scrofa)


name: a (22S)-22-hydroxy C29-steroid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => a C29-steroid + reduced [NADPH--hemoprotein reductase] + O2


name: a triacyl-sn-glycerol + H2O <=> a 2,3-diacyl-sn-glycerol + a fatty acid + H(+)


name: HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1 (Mus musculus)


name: carbon disulfide + H2O <=> carbonyl sulfide + hydrogen sulfide + H(+)


name: Exocytosis of platelet alpha granule contents (Plasmodium falciparum)


name: Methylthio-ribulose-P = Methylthio-ribose-P (Xenopus tropicalis)


name: Activation of Edited Kainate receptors (Homo sapiens)


name: a 3'-end 3'-phospho-ribonucleotide-RNA + GTP => a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + GMP + diphosphate


name: licodione + S-adenosyl-L-methionine => 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+)


name: Formation of clathrin coated vesicle (Rattus norvegicus)


name: cholesteryl (7Z)-octadecenoate + CoA => (7Z)-octadecenoyl-CoA + cholesterol


name: sphinganine + (9Z)-octadecenoyl-CoA <=> N-(9Z-octadecenoyl)-sphinganine + CoA + H(+)


name: a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O => an acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acid + H(+)


name: AKR1B1 reduces Glc to D-sorbitol (Bos taurus)


name: WLS dissociates from retromer (Rattus norvegicus)


name: prostaglandin G1 + AH2 => prostaglandin H1 + A + H2O


name: glycocholate + an L-alpha-amino acid = an N-choloyl-L-alpha-amino acid + glycine


name: PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Homo sapiens)


name: tetradecan-1-ol + 1-hexadecanoylglycerone 3-phosphate = 1-O-tetradecylglycerone 3-phosphate + hexadecanoate + H(+)


name: cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Mus musculus)


name: gypsogenin + reduced [NADPH--hemoprotein reductase] + O2 <=> gypsogenate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: balenine + H2O => N(tele)-methyl-L-histidine + beta-alanine


name: Formation of the RBBP5:ASH2L heterodimer (Drosophila melanogaster)


name: GRB2:SOS1 binds to phosphorylated SHC1 in complex with EGFR (Bos taurus)


name: NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) (Homo sapiens)


name: amidinoproclavaminate + H2O => proclavaminate + urea


name: succinyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+) => 2 oxidized [2Fe-2S]-[ferredoxin] + 2-oxoglutarate + CoA


name: BMP2 binds to the receptor complex (Sus scrofa)


name: p-EPHB phosphorylates SDC2 (Danio rerio)


name: PLK1 binds phosphorylated condensin II complex (Bos taurus)


name: Binding of GPVI:Fc Epsilon R1 gamma receptor complex with collagen (Xenopus tropicalis)


name: prostaglandin E1(out) + 2 (S)-lactate(in) = prostaglandin E1(in) + 2 (S)-lactate(out)


name: umbelliferone + (2E)-geranyl diphosphate => 8-geranylumbelliferone + diphosphate


name: ligand-gated monoatomic cation channel activity


name: antimonite secondary active transmembrane transporter activity


name: Activated PKC-alpha  activate MMP3 (Rattus norvegicus)


name: 17-dehydrostemmadenine + NADP(+) <=> 3,17-didehydrostemmadenine + NADPH


name: 3-hydroxyanthranilate + O2 => 2-amino-3-carboxymuconate semialdehyde (Danio rerio)


name: (S)-lactaldehyde + NADP(+) => methylglyoxal + NADPH + H(+)


name: (2Z,4E)-2,3,5-trichloromuconate + H(+) => 3,4,6-trichlorocatechol + O2


name: an adenosine in tRNA + formaldehyde + succinate + CO2 => an N(1)-methyladenosine in tRNA + 2-oxoglutarate + O2


name: CD28 homodimer binds B7-2 monomer (Homo sapiens)


name: PLK1 phosphorylates FIRRM at S43 (Danio rerio)


name: L-kynurenine + oxaloacetate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + H2O => 1-O-hexadecyl-sn-glycero-3-phosphate + acetate + H(+)


name: ATG12 binds ATG7 dimer (Xenopus tropicalis)


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Xenopus tropicalis)


name: SIRT4 transfers ADPRib to GLUD (Sus scrofa)


name: Active LTK phosphorylates IRS1 (Homo sapiens)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Danio rerio)


name: Methylation of GMP-cap by RNA Methyltransferase (Mus musculus)


name: VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3 (Canis familiaris)


name: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen


name: N-acetylneuraminate + acetate + H(+) => N-acetyl-4-O-acetylneuraminate + H2O


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Homo sapiens)


name: Regeneration of eEF1A:GTP by eEF1B activity (Mus musculus)


name: 3,4-dihydroxyphenylacetaldehyde + NAD(+) + H2O <=> 3,4-dihydroxyphenylacetate + NADH + 2 H(+)


name: 2-(prostaglandin H2)-sn-glycero-3-phosphocholine = 2-(prostaglandin E2)-sn-glycero-3-phosphocholine


name: Hemes:LY96 activates TLR4 (Mus musculus)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,4,5)P3 by MINPP1 in the ER lumen (Danio rerio)


name: "Acting on single donors with incorporation of molecular oxygen (oxygenases). The oxygen incorporated need not be derived from O2"


name: activation of aldosterone biosynthetic process


name: HSPG2 (perlecan) degradation by MMP14, MMP15 (Homo sapiens)


name: PTPN3 dephosphorylates EPS15 (Bos taurus)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Sus scrofa)


name: piceatannol + S-adenosyl-L-methionine <=> rhapontigenin + S-adenosyl-L-homocysteine + H(+)


name: Endorepellin binds alpha2beta1 integrin (Caenorhabditis elegans)


name: ganglioside Gal-(Fuc)-GA1 + UDP-N-acetyl-alpha-D-galactosamine => ganglioside GalNAcGal-(Fuc)-GA1 + UDP + H(+)


name: CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)


name: an N-methyl-L-amino acid + O2 + H2O <=> an L-alpha-amino acid + formaldehyde + H2O2


name: L-dopa + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => L-tyrosine + reduced [NADPH--hemoprotein reductase] + O2


name: 4-aminobutanoate(out) + chloride(out) + 3 Na(+)(out) => 4-aminobutanoate(in) + chloride(in) + 3 Na(+)(in)


name: Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Plasmodium falciparum)


name: MLCL is acylated to CL by LCLAT1 (ER) (Xenopus tropicalis)


name: SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Mus musculus)


name: IL21 receptor STAT binding (Mus musculus)


name: RBX1:CUL3 dissociates from forming autophagosome (Drosophila melanogaster)


name: NT5C2 tetramer phosphorylates RBV (Gallus gallus)


name: beta-D-Glc-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+) => N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-glucose


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA => 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA


name: MT-MMPs are sorted to the plasma membrane (Sus scrofa)


name: acrolein + NAD(+) + H2O => acrylate + NADH + 2 H(+)


name: N-tetradecanoylethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+) => N-tetradecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH + H(+)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 => 21-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 1D-myo-inositol 1-phosphate + an N-acyl-sphingoid base + H(+) => an inositol-1-phosphoceramide + H2O


name: Recruitment of XPA and release of CAK  (Homo sapiens)


name: PLG(20-810) binds anti-fibrinolytics (Sus scrofa)


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Sus scrofa)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Canis familiaris)


name: RABGGTA and RABGGTB bind (Rattus norvegicus)


name: (3R)-citramalyl-CoA => pyruvate + acetyl-CoA


name: positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II


name: pentadecanoate + ATP + CoA = pentadecanoyl-CoA + AMP + diphosphate


name: Activated human JNKs migrate to nucleoplasm (Danio rerio)


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Gallus gallus)


name: Neuromedin-U receptors bind neuromedins U, S (Rattus norvegicus)


name: Fibrillin-1 binds integrins (Bos taurus)


name: Clustering of Integrin alphaIIb beta3 complexes (Rattus norvegicus)


name: SRC1-1 binds SH2D2A and is recruited to VEGFR2 (Rattus norvegicus)


name: CCNK binds CDK12 (Saccharomyces cerevisiae)


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Caenorhabditis elegans)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Danio rerio)


name: AMPK (complex) phosphorylates ULK1 (complex) (Schizosaccharomyces pombe)


name: FAD(in) + AMP(out) <=> FAD(out) + AMP(in)


name: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate => 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+)


name: OAS2 produces oligoadenylates (Homo sapiens)


name: SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) (Canis familiaris)


name: PSMC2 binds PSMC1 (Dictyostelium discoideum)


name: oxalyl-CoA + formate => formyl-CoA + oxalate


name: B3GALNT2 transfers GalNAc to GlcNAc-Man-DAG1 (Danio rerio)


name: hexadecanoyl-AMP + holo-[ACP] => hexadecanoyl-[ACP] + AMP + H(+)


name: a 1-acyl-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA => 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: methanol + NAD(+) => formaldehyde + NADH + H(+)


name: Activation of HCN channels (Xenopus tropicalis)


name: 3-oxooctadecanoyl-CoA + NADPH + H(+) = (3R)-hydroxyoctadecanoyl-CoA + NADP(+)


name: catechol + S-adenosyl-L-methionine <=> guaiacol + S-adenosyl-L-homocysteine + H(+)


name: 3-oxopresphingofungin + holo-[ACP] + CO2 => aminomalonate + (3R)-hydroxyoctadeca-4,10-dienoyl-[ACP]


name: L-tryptophan + S-adenosyl-L-methionine = 2-methyl-L-tryptophan + S-adenosyl-L-homocysteine + H(+)


name: a 2,3-saturated meromycolyl-[ACP] + NAD(+) = a trans-Delta(2)-meromycolyl-[ACP] + NADH + H(+)


name: "meromycolic acid enoyl-[acyl-carrier-protein] reductase"


name: geranylgeranyl diphosphate = fusicocca-2,10(14)-diene + diphosphate


name: Fe(III)-enterobactin(out) + ATP + H2O = Fe(III)-enterobactin(in) + ADP + phosphate + H(+)


name: "ABC-type ferric enterobactin transporter"


name: Formation of the inner ring of the 20S immunoproteasome core particle (Bos taurus)


name: OAT2 and OAT4 mediate transport of sulphate conjugates (Drosophila melanogaster)


name: 5-(9Z-hexadecenoyloxy)-octadecanoate + H2O => 5-hydroxy-octadecanoate + (9Z)-hexadecenoate + H(+)


name: RNA polymerase II CTD heptapeptide repeat Y1 kinase activity


name: N-tetracosanoylsphinganine-(1D-myo-inositol) + GDP-alpha-D-mannose => mannosyl-alpha-1->6-inositol phospho-N-tetracosanoylsphinganine + GDP + H(+)


name: 3-methoxy-5-methylphenol + S-adenosyl-L-methionine <=> 3,5-dimethoxytoluene + S-adenosyl-L-homocysteine + H(+)


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Sus scrofa)


name: negative regulation of nucleotide catabolic process


name: EGF-TM7 receptors bind chondroitin sulphate (Sus scrofa)


name: NOTCH3 gene transcription (Homo sapiens)


name: DHFR gene expression is stimulated by E2F1 (Homo sapiens)


name: D-ribono-1,4-lactone + NADH + H(+) <=> D-ribose + NAD(+)


name: leukotriene B4 + reduced [NADPH--hemoprotein reductase] + O2 <=> 18-hydroxy-leukotriene B4 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: [(1->4)-alpha-D-glucosyl](n) + sucrose => [(1->4)-alpha-D-glucosyl](n+1) + D-fructose


name: miltiradiene + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 => 11-oxomiltiradiene + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + 2 H(+)


name: NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Mus musculus)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME4) (Saccharomyces cerevisiae)


name: Chondroitin 4-sulfate (C4S) can be further sulfated on position 6 by CHST15 (Homo sapiens)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Drosophila melanogaster)


name: ent-isokaurene + reduced [NADPH--hemoprotein reductase] + O2 <=> ent-isokauren-2beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Nuclear DUSPs dephosphorylate MAPKs (Danio rerio)


name: 3-dehydro-4alpha-methylzymosterol + NADPH + H(+) <=> 4alpha-methylzymosterol + NADP(+)


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Bos taurus)


name: FMO1:FAD N-oxidises TAM (Canis familiaris)


name: Gamma-secretase cleaves YBX1:NOTCH3 (Rattus norvegicus)


name: a ganglioside GM1 + H2O => a ganglioside GA1 + N-acetylneuraminate


name: WNT ligands traffic to the plasma membrane (Gallus gallus)


name: 2 reduced [2Fe-2S]-[ferredoxin] + 2 CO2 + NADH + H(+) => 2 formate + 2 oxidized [2Fe-2S]-[ferredoxin] + NAD(+)


name: G alpha (q) in G (q):RGS complex is inactivated (Dictyostelium discoideum)


name: HIF-alpha translocates from cytosol to nucleus (Sus scrofa)


name: ACAT2 condenses 2 Ac-CoA to form ACA-CoA (Saccharomyces cerevisiae)


name: Transfer of Fe-S clusters to SDHB (Sus scrofa)


name: GDP-alpha-D-rhamnose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate => alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: levopimaradienol + NADPH + O2 + H(+) <=> levopimaradienal + NADP(+) + 2 H2O


name: Release of Cytochrome c from mitochondria (Sus scrofa)


name: PPM1E dephosphorylates CAMK4 (Homo sapiens)


name: L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol => L-methionyl-[protein] + [thioredoxin]-disulfide + H2O


name: "RING-type E3 ubiquitin transferase (cysteine targeting)"


name: ent-kaur-16-ene + reduced [NADPH--hemoprotein reductase] + O2 => ent-kaur-16-en-19-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Gbeta:gamma activation of PLC beta (Bos taurus)


name: Formation of dehydro-lysinonorleucine cross-links (Caenorhabditis elegans)


name: prostaglandin H1 + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxyprostaglandin H1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Dermatan-sulfate epimerase (DSE) converts chondroitin sulfate (CS) to dermatan sulfate (DS) (Bos taurus)


name: HK1 phosphorylates Mannose to Man6P (Homo sapiens)


name: Interleukin-23 binds interleukin-23 receptor (Canis familiaris)


name: PAK1 phosphorylates FLNA (Rattus norvegicus)


name: Collagen type XII degradation by MMP12 (Gallus gallus)


name: Caspase-8 activates BID by cleavage (Homo sapiens)


name: (2-aminoethyl)phosphonate + 2-oxoglutarate + O2 => (1R)-(2-amino-1-hydroxyethyl)phosphonate + succinate + CO2


name: RNA endonuclease activity, producing 3'-phosphomonoesters


name: CDK2 phosphorylates TP53 (Canis familiaris)


name: OAT2 and OAT4 mediate transport of sulphate conjugates (Homo sapiens)


name: SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Homo sapiens)


name: The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Canis familiaris)


name: Allergen dependent IgE bound FCERI aggregation (Bos taurus)


name: hancockiamide B + reduced [NADPH--hemoprotein reductase] + O2 <=> hancockiamide C + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: a 2-deoxy-alpha-D-glucoside + H2O <=> 2-deoxy-D-glucose + an alcohol


name: 30-hydroxy-11-oxo-beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2 <=> glycyrrhetaldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: PCSK9 binds PCSK9 inhibitors (Gallus gallus)


name: passive transmembrane transporter activity


name: Formation of ORC(1-6) complex (Rattus norvegicus)


name: positive regulation of macrophage inflammatory protein production


name: SGK phosphorylates SRF (Schizosaccharomyces pombe)


name: oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor


name: phosphate(in) + ATP(out) + 2 H(+)(out) <=> phosphate(out) + ATP(in) + 2 H(+)(in)


name: 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + hydrogencarbonate + ATP = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate + 2 H(+)


name: Association of procollagen type XXIII (Bos taurus)


name: 20-oxo-5-O-beta-D-mycaminosyltylonolide + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 5-O-beta-D-mycaminosyltylonolide + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: dethiobiotin transmembrane transporter activity


name: IQGAPs bind F-actin, which is inhibited by calmodulin (Danio rerio)


name: Inactivation of Myt1 kinase (Rattus norvegicus)


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Plasmodium falciparum)


name: a ganglioside Gal-GD1b (d18:1(4E)) + GDP-beta-L-fucose => a ganglioside Gal(Fuc)-GD1b (d18:1(4E)) + GDP + H(+)


name: BRWD1 binds AcK(9,14,18,79)-p(S10,T11)-histone H3 (Homo sapiens)


name: PalmS-ESRs:CAVs translocate to plasma membrane (Sus scrofa)


name: 7-oxocholesterol + NADPH + H(+) = 7alpha-hydroxycholesterol + NADP(+)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine => 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Increased Spinal Cord Nerve Growth Factor Activity


name: prostaglandin F2alpha(in) + 2-oxoglutarate(out) => prostaglandin F2alpha(out) + 2-oxoglutarate(in)


name: IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)


name: Dissociation of the Gi alpha:G olf complex (Sus scrofa)


name: PTK6 phosphorylates KHDRBS2 (Xenopus tropicalis)


name: L-idonate(in) + H(+)(in) => L-idonate(out) + H(+)(out)


name: L-proline(in) + Na(+)(in) => L-proline(out) + Na(+)(out)


name: LUM (lumican) binds integrin alpha2beta1 (Xenopus tropicalis)


name: (3E)-2-oxohex-3-enedioate + H(+) <=> 2-oxopent-4-enoate + CO2


name: sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential


name: (3R)-hydroxy-(14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontahexaenoyl-CoA <=> (2E,14Z,17Z,20Z,23Z,26Z,29Z)-dotriacontaheptaenoyl-CoA + H2O


name: beta-D-glucosyl-(1->3)-O-lithocholate + H2O => lithocholate + D-glucose


name: RAC2 binds effectors at the ER membrane (Homo sapiens)


name: regulation of high-potential iron-sulfur carrier


name: L-asparagine(in) + L-glutamine(out) + Na(+)(out) <=> L-asparagine(out) + L-glutamine(in) + Na(+)(in)


name: S-(hercyn-2-yl)-L-cysteine S-oxide + AH2 + H(+) = ergothioneine + pyruvate + A + NH4(+)


name: AFG3L2 binds mitochondrial matrix proteins (Gallus gallus)


name: (S)-3-methyl-2-oxopentanoate + NAD(+) + CoA = 2-methylbutanoyl-CoA + CO2 + NADH


name: Digestion of linear starch (amylose) by extracellular amylase (Rattus norvegicus)


name: NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Canis familiaris)


name: alpha-isomaltosyl-(1->4)-D-maltotriose + D-maltotriose => 2 D-maltotetraose


name: SLC25A1 exchanges CIT and MAL (Drosophila melanogaster)


name: YME1L1 proteolyzes unassembled proSMDT1 (Canis familiaris)


name: IL24:IL22RA1:p-JAK1:IL20RB binds STAT3 (Rattus norvegicus)


name: (2E)-geraniol + ATP = (2E)-geranyl phosphate + ADP + H(+)


name: 7(1)-hydroxychlorophyllide a + NADPH + O2 + H(+) => chlorophyllide b + NADP(+) + 2 H2O


name: 3-hydroxy-2-methylpyridine-5-carboxylate + NADH + O2 => 2-(acetamidomethylene)succinate + NAD(+)


name: MAPKs phosphorylate ETS1 and ETS2 (Gallus gallus)


name: nitrate transmembrane transporter activity


name: Cleavage of ERBB4m80 by gamma-scretase complex (Gallus gallus)


name: guanine + 5-phospho-alpha-D-ribose 1-diphosphate => GMP + diphosphate


name: positive regulation of interleukin-17-mediated signaling pathway


name: Beta-defensins are secreted (Sus scrofa)


name: 1-phenylpropylamine + pyruvate = 1-phenylpropan-1-one + L-alanine


name: HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer (Caenorhabditis elegans)


name: 1-acyl LPC is acylated to PC by LPCAT (Canis familiaris)


name: dTDP-4-amino-4,6-dideoxy-alpha-D-galactose + 2-oxoglutarate => dTDP-4-dehydro-6-deoxy-alpha-D-glucose + L-glutamate


name: 5-dehydro-D-gluconate + NADP(+) = 2,5-didehydro-D-gluconate + NADPH + H(+)


name: Furin cleaves pro-factor VII to factor VII (Bos taurus)


name: 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) => 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: FMN(in) + CoA(out) <=> FMN(out) + CoA(in)


name: (10Z,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADP(+) => (2E,10Z,13Z,16Z,19Z,22Z,25Z)-octacosaheptaenoyl-CoA + NADPH + H(+)


name: (2E,11Z,14Z,17Z)-eicosatetraenoyl-CoA + H2O => (3R)-hydroxy-(11Z,14Z,17Z)-eicosatrienoyl-CoA


name: holo-[peptidyl-carrier protein] + glycine + ATP <=> glycyl-[peptidyl-carrier protein] + AMP + diphosphate


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Rattus norvegicus)


name: (1R,4S)-camphene + diphosphate => (2E)-geranyl diphosphate


name: PCSK9:LDLR bind to Clathrin (Mus musculus)


name: Activation of proMMP11 by FURIN (Caenorhabditis elegans)


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Xenopus tropicalis)


name: trichloroethene + chloride + A + H(+) => tetrachloroethene + AH2


name: nickel cation transmembrane transporter activity


name: Parathyroid hormone receptor can bind parathyroid hormone (Bos taurus)


name: GSTO1 dimer reduces methylarsonate to methylarsonite (Homo sapiens)


name: an N-(1,2 saturated very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(III)-[cytochrome b5] + H2O


name: 7(1)-hydroxychlorophyll a + NAD(+) = chlorophyll b + NADH + H(+)


name: isopentenyl diphosphate biosynthetic process, mevalonate pathway


name: an aldehyde + glycerol => a 1-(1-hydroxyalkyl)-sn-glycerol


name: MBTPS1 (S1P) cleaves CREB3 (Gallus gallus)


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) => 4,5-dihydroxyphthalate + NADH + H(+)


name: DSPGs are secreted (Drosophila melanogaster)


name: Ral-GDS binds to Ras-GTP (Rattus norvegicus)


name: L-proline + NAD(+) => (S)-1-pyrroline-5-carboxylate + NADH + 2 H(+)


name: 2-oxohexanoate + L-kynurenine => L-2-aminohexanoate + kynurenate + H2O


name: FOXO1,FOXO3,FOXO4 bind IGFBP1 gene promoter (Homo sapiens)


name: 1-hexadecanoyl-2-(5-oxopentanoyl)-sn-glycero-3-phosphocholine + H2O = 5-oxopentanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: alpha-methylacetoacetyl-CoA + NADH + H+ <=> alpha-methyl-beta-hydroxybutyryl-CoA + NAD+ (Caenorhabditis elegans)


name: CDK6 binds RUNX1 (Drosophila melanogaster)


name: an S-substituted L-cysteine + acetate => an N-acetyl-L-cysteine-S-conjugate + H2O


name: CYB5R3:FAD reduces CYB5A:ferriheme to CYB5A:heme (Drosophila melanogaster)


name: MKRN1 polyubiquitinates PTEN (Caenorhabditis elegans)


name: ent-8alpha-hydroxylabd-13-en-15-yl diphosphate => ent-13-epi-manoyl oxide + diphosphate


name: inhibitory killer cell immunoglobulin-like receptor signaling pathway


name: L3MBTL1 binds TP53 monomethylated on K382 (Rattus norvegicus)


name: CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Canis familiaris)


name: The SMAD2/3:SMAD4 complex transfers to the nucleus (Drosophila melanogaster)


name: diisopropyl fluorophosphate + H2O = diisopropyl phosphate + fluoride + 2 H(+)


name: regulation of tyrosine phosphorylation of Stat6 protein


name: 8-oxo-GDP + H2O => 8-oxo-GMP + phosphate + H(+)


name: JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Homo sapiens)


name: glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Mus musculus)


name: Digestion of monoacylglycerols by extracellular CEL (bile salt-dependent lipase) (Xenopus tropicalis)


name: a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine => a 1,2-diacyl-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)


name: PAQR3 binds inactive RAFs (Rattus norvegicus)


name: alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-Glc + GDP + H(+) => alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-D-Glc + GDP-beta-L-fucose


name: 3'-deoxy-3',4'-didehydro-UTP + 5'-deoxyadenosine + L-methionine + A + H2O + H(+) => UTP + AH2 + S-adenosyl-L-methionine


name: 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA


name: Activation of PAKs by RAC1 and CDC42 (Caenorhabditis elegans)


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + di-trans,octa-cis-undecaprenyl diphosphate <=> an alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Drosophila melanogaster)


name: N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + CO2 + NADP(+) + H2O => (S)-2-amino-6-oxohexanoyl-[protein] + (7R,8S)-8-amino-7-(carboxyamino)nonanoate + NADPH + 3 H(+)


name: L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl-[ribulose-1,5-bisphosphate carboxylase] + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: Translocation of CaN:CaM:NFAT to nucleus (Xenopus tropicalis)


name: PLG(20-810) binds aprotinin (Canis familiaris)