name: (3S)-3-isopropenyl-6-oxoheptanoate + H(+) => (4S,7S)-7-hydroxy-4-isopropenyl-7-methyloxepan-2-one


name: 3-aminopropanal + spermidine + H2O2 => spermine + O2 + H2O


name: IL19:IL20RA:p‑JAK1:IL20RB binds STAT3 (Mus musculus)


name: 5alpha-cholest-8-en-3-one + CO2 + NADH => 4alpha-carboxy-5alpha-cholest-8-ene-3beta-ol + NAD(+)


name: an N-acyl-1,2-diacyl-sn-glycero-3-phosphoethanolamine + H2O => N,1-diacyl-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: Decreased Midbrain Acetylcholine Activity


name: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + D-alanine + H2O => 2-methylserine + (6S)-5,6,7,8-tetrahydrofolate


name: SOS1-mediated nucleotide exchange of RAS (EGF:EGFR:SHC1:GRB2:SOS1) (Bos taurus)


name: ent-7alpha-hydroxykaur-16-en-19-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => ent-kaur-16-en-19-oate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: SCF-beta-TrCp1/2 ubiquitinates phosphorylated BORA (Homo sapiens)


name: SC5D desaturates LTHSOL to 7-dehydroCHOL (Danio rerio)


name: PARP1,PARP2 dimers bound to FEN1 and POLB autoPARylate (Canis familiaris)


name: Secretion and activation of the latent large complex of TGF-beta-1 (Gallus gallus)


name: a ganglioside GM1 + GDP-beta-L-fucose = a ganglioside Fuc-GM1 + GDP + H(+)


name: pro-SFTPB translocates from ER membrane to multivesicle body (Caenorhabditis elegans)


name: DIT and MIT combine to form triiodothyronine (Canis familiaris)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + ATP = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphate + ADP + H(+)


name: [(1->4)-6-phospho-alpha-D-glucosyl](n) + n ATP + n H2O <=> [(1->4)-3,6-bisphospho-alpha-D-glucosyl](n) + n AMP + n phosphate + 2n H(+)


name: (PP)2-IP4 is dephosphorylated to 5-PP-IP5 by NUDT(1) in the cytosol (Homo sapiens)


name: alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP => di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose


name: agmatine(out) + H(+)(in) => agmatine(in) + H(+)(out)


name: Formation of C-strand Okazaki fragments (Mus musculus)


name: PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane (Mus musculus)


name: AWAT2 transfers PALM to 11cROL forming 11cRPALM (Mus musculus)


name: acyltransferase activity, transferring groups other than amino-acyl groups


name: Peptide transfer from P-site tRNA to the A-site tRNA (Homo sapiens)


name: TICAM1 deficiency blocks TLR3 pathway (Homo sapiens)


name: P2RX4,7 binds itself to form trimeric non-selective cation channels (Homo sapiens)


name: PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Bos taurus)


name: D-dopa + O2 + H2O <=> 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+)


name: Hydroperoxyl enters the bacterium (Homo sapiens)


name: arsenate(in) + ATP + H2O => arsenate(out) + ADP + phosphate + H(+)


name: D-aspartyl-tRNA(Asp) + H2O => tRNA(Asp) + D-aspartate + H(+)


name: isocitrate + NADP+ => 2-oxoglutarate + CO2 + NADPH + H+ (Schizosaccharomyces pombe)


name: Removal of fibrillar collagen N-propeptides (Sus scrofa)


name: (S)-3-hydroxy-2-oxobutanoate + H2O2 + NH4(+) => D-threonine + O2 + H2O


name: a 3-acylpyruvate + H2O <=> a carboxylate + pyruvate + H(+)


name: Ubiquitinated DVL1 is degraded by the proteasome (Bos taurus)


name: CYP4F11 16-hydroxylates 3OH-PALM (Sus scrofa)


name: SREBP1A,2 binds the MVD promoter (Homo sapiens)


name: catechol + NADPH + H(+) => (1S,2S)-1,2-dihydrobenzene-1,2-diol + NADP(+)


name: 1,3,7-trimethyl-5-hydroxyisourate + NAD(+) + H2O => 1,3,7-trimethylurate + NADH + O2 + H(+)


name: coenzyme B + coenzyme M + fumarate => coenzyme M-coenzyme B heterodisulfide + succinate


name: (2E,6E)-farnesyl diphosphate = (1R,4R,5S)-acoradiene + diphosphate


name: SARS-CoV-2 nsp16 binds to U1 snRNA (Homo sapiens)


name: 7-cyano-7-carbaguanosine(15) in tRNA + L-lysine = 7-N-[(5S)-5-amino-5-carboxypentyl]formamidino-7-deazaguanosine(15) in tRNA


name: (4R)-4-hydroxy-2-oxoglutarate <=> glyoxylate + pyruvate


name: AMP + phosphate = alpha-D-ribose 1,5-bisphosphate + adenine


name: a pseudouridine in rRNA => a uridine in rRNA


name: a 5'-end NAD(+)-phospho-ribonucleoside in snoRNA + H2O = a 5'-end phospho-ribonucleoside in snoRNA + NAD(+) + H(+)


name: p-T774-PKN1 phosphorylates PPP1R14A (Canis familiaris)


name: ROBO signaling pathway involved in axon chemotaxis


name: L-lactate dehydrogenase (cytochrome) activity


name: ALD3A1 oxidises 4HPCP to CXPA (Bos taurus)


name: USP43 deISGylates ISG:K164,ISG:K168-PCNA (Sus scrofa)


name: sarcosine + (6S)-5,6,7,8-tetrahydrofolate + O2 <=> (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O2


name: 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + ATP + CoA = 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA + AMP + diphosphate


name: TGFBR3 binding to FGF2 (Xenopus tropicalis)


name: BAR domain proteins recruit dynamin (Gallus gallus)


name: a 2-hydroxy-3-methyl fatty acyl-CoA + succinate + CO2 => a 3-methyl fatty acyl-CoA + 2-oxoglutarate + O2


name: calcium ion transmembrane import into cytosol


name: L-leucine(out) + L-methionine(in) = L-leucine(in) + L-methionine(out)


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Rattus norvegicus)


name: L-phenylalanine(out) + chloride(out) + 2 Na(+)(out) => L-phenylalanine(in) + chloride(in) + 2 Na(+)(in)


name: TLE tetramers bind TCF/LEF at WNT promoters (Caenorhabditis elegans)


name: dTDP-4-dehydro-6-deoxy-alpha-D-glucose => dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O


name: a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H2O <=> a 5'-end dephospho-2'-deoxyribonucleoside-DNA + phosphate


name: 5,7-dibromo-indole-3-carbonitrile + 2,3,5-tribromoindole + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = aetokthonotoxin + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Mus musculus)


name: (S)-4,5-dihydroxypentane-2,3-dione + ATP => (2S)-2-hydroxy-3,4-dioxopentyl phosphate + ADP + H(+)


name: TIAM1 exchanges GTP for GDP on RAC1, activating it (Mus musculus)


name: (S)-2,3-epoxysqualene + H2O => dammarenediol-II


name: (2E)-eicosenoyl-CoA + NADPH + H(+) <=> eicosanoyl-CoA + NADP(+)


name: (Z)-1,2-dichloroethene + AH2 <=> chloroethene + chloride + A + H(+)


name: estrone 3-sulfate(out) + succinate(in) = estrone 3-sulfate(in) + succinate(out)


name: a cytidine(6-4)cytidine in DNA <=> a cytidine dimer in DNA + H(+)


name: activation of glucose catabolic process to lactate via pyruvate


name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA (Homo sapiens)


name: CCNB1:p-T160-CDK1 phosphorylates NUMA1 (Homo sapiens)


name: HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Drosophila melanogaster)


name: 3,6-anhydro-L-galactonate + NADH + 2 H(+) => 3,6-anhydro-alpha-L-galactopyranose + NAD(+) + H2O


name: Defective MPDU1 does not promote transfer of Man to N-glycan precursor (GlcNAc)2 (Man)7 (PP-Dol)1 by ALG12 (Homo sapiens)


name: MHC class II antigen processing (Sus scrofa)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1-O-(1Z)-alkenyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: shikimate + (E)-caffeate + H(+) => 5-O-[(E)-caffeoyl]-shikimate + H2O


name: a mannosylinositol-1-phospho-N-acyl-sphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) => an inositol phosphomannosylnositol-1-phospho-N-acylsphingoid base + a 1,2-diacyl-sn-glycerol


name: 4 porphobilinogen + H2O <=> hydroxymethylbilane + 4 NH4(+)


name: reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase activity


name: limonene 1,2-epoxide + NADP(+) + H2O => (4R)-limonene + NADPH + O2 + H(+)


name: 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O => (2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 + H(+)


name: a 1-acyl-2-[(3E)-hexadec-3-enoyl]-glycerolipid + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O => a 1-acyl-2-hexadecanoyl-glycerolipid + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: nitrate(out) + 2 Na(+)(out) <=> nitrate(in) + 2 Na(+)(in)


name: PNP catalyzes the conversion of hypoxanthine and (deoxy)ribose to (deoxy)inosine (Bos taurus)


name: 3 malonyl-CoA + acetyl-CoA + 2 H(+) <=> orsellinate + 3 CO2 + 4 CoA


name: 3-O-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => O(3)-{N-acetyl-beta-D-glucosaminyl-(1->2)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-alpha-D-mannosyl}-L-threonyl-[protein] + UDP + H(+)


name: Recruitment of Grb2 to pFAK:NCAM1 (Rattus norvegicus)


name: L-idonate + NAD(+) <=> 2-dehydro-L-idonate + NADH + H(+)


name: IAA-amino acid conjugate hydrolase activity


name: positive regulation of glucose catabolic process to lactate via pyruvate


name: IDS hydrolyses Heparan sulfate chain(5) (Danio rerio)


name: PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Mus musculus)


name: androst-4-ene-3,17-dione + acetate + NADP(+) + H2O => 17alpha-hydroxyprogesterone + NADPH + O2


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Canis familiaris)


name: prostaglandin F2alpha 1-glyceryl ester + H2O = prostaglandin F2alpha + glycerol + H(+)


name: imidazol-4-one + H2O <=> N-formimidoylglycine


name: pyruvate + CO2 => acetylenedicarboxylate + H2O + H(+)


name: Addition of nucleotides leads to transcript elongation (Mus musculus)


name: SREBP1A,1C,2 binds the HMGCS1 promoter (Homo sapiens)


name: tRNA(Asn) + L-asparagine + ATP <=> L-asparaginyl-tRNA(Asn) + AMP + diphosphate + H(+)


name: Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3 (Bos taurus)


name: regulation of acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]


name: dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + AH2 + O2 = dTDP-beta-L-evernitrose + A + H2O


name: (2E,6E)-farnesyl diphosphate => trichodiene + diphosphate


name: SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP (Rattus norvegicus)


name: PTEN undergoes monoubiquitination (Xenopus tropicalis)


name: Reactive Blue 5 + 2 H2O2 => 2,2'-disulfonyl azobenzene + 3-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]benzenesulfonate + phthalate + 2 H2O + 2 H(+)


name: ochratoxin B + ADP + phosphate + H(+) => 7-carboxymellein + L-phenylalanine + ATP


name: uridine(out) + 2 Na(+)(out) => uridine(in) + 2 Na(+)(in)


name: 2 3-(4-hydroxyphenyl)pyruvate + H(+) <=> (2S)-2-(4-hydoxybenzyl)-3-(4-hydroxyphenyl)-2-furonol carboxylate + H2O


name: CHEK2 phosphorylates TP53 (Xenopus tropicalis)


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Xenopus tropicalis)


name: Furin cleaves ANTXR2-bound pagA to yield pagA(197-794) (Homo sapiens)


name: Beta-galactosidases hydrolyse mobilized GM1 to mobilized GM2 (Bos taurus)


name: 1-O-(alk-1-enyl)-sn-glycero-3-phosphate + H2O = 1-O-(alk-1-enyl)-sn-glycerol + phosphate


name: Condensin II complex binds H4K20me1-containing nucleosomes (Plasmodium falciparum)


name: Interaction of PECAM-1 and SHP-1 (Sus scrofa)


name: L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine => 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-threonyl-[protein] + UDP + H(+)


name: (1R)-(1-hydroxyethyl)phosphonate + O2 => acetate + phosphate + 2 H(+)


name: AQP1 tetramer transports CO2 from extracellular region to cytosol (Drosophila melanogaster)


name: (S)-3-methyl-2-oxopentanoate + L-valine <=> 3-methyl-2-oxobutanoate + L-isoleucine


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Mus musculus)


name: beta-citrylglutamate(in) + ATP + H2O = beta-citrylglutamate(out) + ADP + phosphate + H(+)


name: 6alpha,8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate + reduced [NADPH--hemoprotein reductase] + O2


name: 2''-O-lipoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein] => N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NAD(+) + H2O


name: Latent TGF-beta-3 binds integrins (Caenorhabditis elegans)


name: (2S,4S)-4-hydroxy-4-methylglutamate + 8 malonyl-CoA + 3 S-adenosyl-L-methionine + ATP + 8 NADPH + 11 H(+) = (2S)-3-[(2S)-3,5-dioxo-4-[(2E,4R,6R,8E,10E,12E)-4,6,12-trimethyltetradeca-2,8,10,12-tetraenoyl]pyrrolidin-2-yl]-2-hydroxy-2-methylpropanoate + AMP + 3 S-adenosyl-L-homocysteine + 8 CO2 + diphosphate + 8 NADP(+) + 8 CoA + 6 H2O


name: 2-amino-5-chlorophenol + O2 = 2-amino-5-chloromuconate 6-semialdehyde


name: 1-tetradecanoyl-sn-glycero-3-phosphocholine <=> 1-tetradecanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: N,N',N'',N'''-tetraacetylchitotetraono-1,5-lactone + H2O = N,N',N'',N'''-tetraacetylchitotetraonate + H(+)


name: SGT1:HSP90 binds inactive NLRP3 (Rattus norvegicus)


name: Protesomal degradation of K48polyUb-TRAF3 (Sus scrofa)


name: 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA => 1-octanoyl-2-(9Z)-octadecenoyl-sn-glycerol + CoA


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Homo sapiens)


name: a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine <=> a 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP + H(+)


name: 2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O => propanoyl-CoA + hydrogencarbonate + NADH + H(+)


name: serine-type endopeptidase inhibitor activity


name: prostaglandin A2 + glutathione <=> prostaglandin A2-S-(S)-glutathione


name: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + 2 H2O => 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: cyclohexane-1-carbonyl-CoA + butanoate => cyclohexane-1-carboxylate + butanoyl-CoA


name: AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP (Mus musculus)


name: (1S,2S)-OPC-8 + ATP + CoA => OPC8-CoA + AMP + diphosphate


name: 2',3'-cUAMP + 2 diphosphate => UTP + ATP


name: prostaglandin D2-ethanolamide + NADPH + H(+) <=> 11beta-prostaglandin F2-ethanolamide + NADP(+)


name: lactose, galactose:hydrogen symporter activity


name: PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body (Homo sapiens)


name: glutamate biosynthesis, using glutamate synthase (NADPH)


name: 9-cis-retinal + reduced [NADPH--hemoprotein reductase] + O2 => 9-cis-retinoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: PSAP(195-273) dimer:PE binds and mobilizes ligands (Caenorhabditis elegans)


name: Sumoylation Regulation of Transcriptional Repression Pathway


name: mercaptopurine + S-adenosyl-L-methionine => 6-methylthiopurine + S-adenosyl-L-homocysteine + H(+)


name: MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Canis familiaris)


name: Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8) (Bos taurus)


name: Formation of collagen fibrils (Homo sapiens)


name: G-protein alpha subunit is inactivated (Xenopus tropicalis)


name: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + NAD(+) + H2O => 3-dehydroquinate + NH4(+) + NADH + H(+)


name: 3-methyl-1,2-didehydro-2,3-dihydrosqualene + S-adenosyl-L-methionine <=> 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene + S-adenosyl-L-homocysteine + H(+)


name: a (3R)-hydroxyacyl-[ACP] + L-ornithine <=> a lyso-ornithine lipid + holo-[ACP] + H(+)


name: ATP13A1 transports Mn2+ from cytosol to ER lumen (Caenorhabditis elegans)


name: CLEC4E binds alpha-mannan and trehalose-6-6'-dimycolate (Rattus norvegicus)


name: ATP7A transports cytosolic Cu2+ to extracellular region (Homo sapiens)


name: a ganglioside GD2 + UDP-alpha-D-galactose => a ganglioside GD1b + UDP + H(+)


name: RNA polymerase II CTD heptapeptide repeat S2 kinase activity


name: ST8SIA2,3,6 transfer Neu5Ac to terminal Gal of N-glycans (Rattus norvegicus)


name: 2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA + H2O = 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)


name: taurocholate(out) + glutarate(in) <=> taurocholate(in) + glutarate(out)


name: SLC6A18 transports Gly from extracellular region to cytosol (Danio rerio)


name: C4b binds to cell surface (Mus musculus)


name: TMP, (d)UMP, uridine 2' monophosphate, or uridine 3'-monophosphate + H2O => thymidine, deoxyuridine, or uridine + orthophosphate [NT5M] (Xenopus tropicalis)


name: I-Smad competes with R-Smad1/5/8 for type I receptor (Bos taurus)


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Caenorhabditis elegans)


name: FLIP(L) and procaspase-8 form heterodimer in TRAIL signaling (Homo sapiens)


name: thyroid hormone transmembrane transporter activity


name: ASIC3 channel blockers bind ASIC3 trimer (Rattus norvegicus)


name: 2xPDXK:2xZn2+ phosphorylates PXA (Sus scrofa)


name: HSBP1 oligomer binds ESRs (Drosophila melanogaster)


name: IL20 binds IL20RA:JAK1:IL20RB (Rattus norvegicus)


name: 2-dehydro-3-deoxy-D-gluconate + ATP => 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + H(+)


name: stimulation of antigen processing and presentation of peptide antigen


name: Formation of MCM2-7 complex (Plasmodium falciparum)


name: miR-17 microRNA binds VAPA mRNA (Homo sapiens)


name: PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Xenopus tropicalis)


name: (R)-benzoin + NADP(+) => benzil + NADPH + H(+)


name: 1,2-dioctanoyl-3-O-beta-D-galactosyl-sn-glycerol + H2O <=> 2-octanoyl-3-O-beta-D-galactosyl-sn-glycerol + octanoate + H(+)


name: cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Canis familiaris)


name: FMN(in) + CoA(out) => FMN(out) + CoA(in)


name: voltage-gated sodium channel activity involved in cardiac muscle cell action potential


name: AGRN binds Beta amyloid fibril via GAG chains (Drosophila melanogaster)


name: TRIM21 ubiquitinates SQSTM1 (Homo sapiens)


name: N-(4-aminobutyl)-3-aminopropanal + acrolein => spermine dialdehyde


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Drosophila melanogaster)


name: Recruitment of GRB2 to p-PTK2 (Bos taurus)


name: 2 GTP + H(+) <=> P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate


name: vitamin B6 transmembrane transporter activity


name: G alpha (z) in G alpha (z):RGS complex is inactivated (Caenorhabditis elegans)


name: CTP + formate + H(+) => dCTP + CO2 + H2O


name: glycolate(out) + (S)-malate(in) => glycolate(in) + (S)-malate(out)


name: D-arginine(out) + L-ornithine(in) => D-arginine(in) + L-ornithine(out)


name: dimethylallyl diphosphate + H2O = prenol + diphosphate


name: L-rhamnofuranose + NADP(+) <=> L-rhamnono-1,4-lactone + NADPH + H(+)


name: dimethylallyl diphosphate + L-glutamate => prekainate + diphosphate


name: FAR1 reduces PalmCoA to HXOL (Canis familiaris)


name: (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NADP(+) = 3-(4-hydroxyphenyl)pyruvate + NADPH + H(+)


name: COPII coat binds TRAPPCII and RAB1:GDP (Caenorhabditis elegans)


name: NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Xenopus tropicalis)


name: 1,2-dioctanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O <=> 2-octanoyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + octanoate + H(+)


name: N-(2,3-dihydroxytetracosanoyl)-(4R)-hydroxysphinganine + NADP(+) + H2O => N-(2-hydroxytetracosanoyl)-(4R)-hydroxysphinganine + NADPH + O2 + H(+)


name: (R)-2-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + NADH + H(+)


name: an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine + a (9Z,12Z)-octadecadienoyl-containing triacyl-sn-glycerol <=> an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine + a diacylglycerol


name: PIAS4 SUMOylates TOP2A with SUMO2,3 (Xenopus tropicalis)


name: KAT5 acetylates ATM at DNA DSBs (Rattus norvegicus)


name: DDX5 binds ESR1:estrogen:TFF1 gene promoter (Mus musculus)


name: Autophosphorylation of SRC (Caenorhabditis elegans)


name: SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Homo sapiens)


name: Arachidonate is hydroxylated to 18-HETE by CYP(1) (Sus scrofa)


name: Cytosolic ACOTs hydrolyse MCFA-CoA, LCFA-CoA (Xenopus tropicalis)


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Canis familiaris)


name: Insulin receptor de-phosphorylation (Canis familiaris)


name: Calmodulin activates Cam-PDE 1 (Drosophila melanogaster)


name: S-sulfanylglutathione + O2 + H2O => sulfite + glutathione + 2 H(+)


name: N(6)-octadecanoyl-L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] + CoA + H(+) => L-lysyl-/S-(2E,6E,10E)-geranylgeranyl-L-cysteinyl-[protein] + octadecanoyl-CoA


name: an aryl sulfate + H2O => a phenol + sulfate + H(+)


name: CDO binds promyogenic cadherins (Homo sapiens)


name: ATM phosphorylates DYRK2 (Drosophila melanogaster)


name: activation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands


name: ARMS is phosphorylated by active TrkA receptor (Rattus norvegicus)


name: 2-O-(beta-D-mannosyl-(1->2)-beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP + H(+) => 2-O-(beta-D-mannosyl)-bis(myo-inositol) 1,3'-phosphate + GDP-alpha-D-mannose


name: RANBP2 SUMOylates HDAC4 with SUMO1 (Homo sapiens)


name: MAPK6 is degraded by the 26S proteasome (Schizosaccharomyces pombe)


name: 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: 1-hexanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-hexanoyl-sn-glycero-3-phosphate + choline + H(+)


name: L-tryptophan + NADP(+) + H2O <=> indole-3-pyruvate + NH4(+) + NADPH + H(+)


name: D-glycero-beta-D-manno-heptose 1,7-bisphosphate + H2O => D-glycero-beta-D-manno-heptose 1-phosphate + phosphate


name: Active FLT3:p-Y-GRB10 binds PIK3R1 (Sus scrofa)


name: 4-nitrobenzaldehyde + NADPH + H(+) <=> 4-nitrobenzyl alcohol + NADP(+)


name: acetyl-CoA + CO2 + NADH => pyruvate + NAD(+) + CoA


name: BPI binds LPS on the bacterial surface (Xenopus tropicalis)


name: GPX4-2 reduces 18(R)-HpEPE to 18(R)-HEPE (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phosphocholine(in) + ATP + H2O => a 1,2-diacyl-sn-glycero-3-phosphocholine(out) + ADP + phosphate + H(+)


name: Loading of antigenic peptides on to class I MHC (Gallus gallus)


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Dictyostelium discoideum)


name: 2-(9Z-octadecenoyl)-glycerol + octanoyl-CoA <=> 1-octanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: 5alpha-pregnan-20beta-ol-3-one + NAD(+) = 5alpha-pregnane-3,20-dione + NADH + H(+)


name: Collagen type II degradation by MMP1,3,8,13,PRSS2 (Mus musculus)


name: sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycero-3-phosphate + choline + H(+)


name: (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-3-phospho-glycerate + H2O <=> (2R)-2-O-[alpha-D-mannopyranosyl-(1->2)-alpha-D-glucopyranosyl]-glycerate + phosphate


name: D-glyceraldehyde 3-phosphate + L-arginine => N(2)-(2-carboxyethyl)-L-arginine + phosphate + H(+)


name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Mus musculus)


name: PTPLs dehydrate VLC3HA-CoA to VLCTDA-CoA (Bos taurus)


name: VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8 (Gallus gallus)


name: (3Z)-hex-3-en-1-ol + benzoyl-CoA => (3Z)-hex-3-en-1-yl benzoate + CoA


name: acetaldehyde + NH4(+) + phosphate => phosphoethanolamine + H2O


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Mus musculus)


name: histone H3K9 trimethyltransferase activity


name: NCAM1 trans-homophilic interaction (Homo sapiens)


name: SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Rattus norvegicus)


name: FECH binds Fe2+ to PRIN9 to form heme (Schizosaccharomyces pombe)


name: N-acetyl-L-aspartate(in) + ATP + H2O <=> N-acetyl-L-aspartate(out) + ADP + phosphate + H(+)


name: (9Z)-hexadecenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine <=> 1-acyl-2-(9Z)-hexadecenoyl-sn-glycero-3-phosphocholine + CoA


name: misfolded CFTR is degraded by the 26S proteasome (Plasmodium falciparum)


name: 14-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate => (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + O2


name: Aquaporin-7 passively transports glycerol out of cell (Schizosaccharomyces pombe)


name: alectinib resistant ALK mutants don't bind alectinib (Homo sapiens)


name: oxidoreductase activity, oxidizing metal ions, oxygen as acceptor


name: Elastin cross-linking by lysyl oxidase (Mus musculus)


name: 3 ATP => 3',3',3'-c-tri-AMP + 3 diphosphate


name: Release of CSK from SRC (Canis familiaris)


name: oxidoreductase activity, acting on other nitrogenous compounds as donors, other acceptors


name: 5-methylcytidine(72) in tRNA + S-adenosyl-L-homocysteine + H(+) => cytidine(72) in tRNA + S-adenosyl-L-methionine


name: 2 5'-dehydroinosine + O2 <=> 2 9-riburonosylhypoxanthine + 2 H(+)


name: 4,8-dihydroxycasbene + reduced [NADPH--hemoprotein reductase] + O2 => 4,5,8-trihydroxycasbene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Mus musculus)


name: ATM phosphorylates DYRK2 (Schizosaccharomyces pombe)


name: CDK and DDK associate with the Mcm10:pre-replicative complex (Sus scrofa)


name: NTRK3 phosphorylates SHC1 (Homo sapiens)


name: N-terminal L-arginyl-[protein] + L-leucyl-tRNA(Leu) = N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu) + H(+)


name: EP300 is recruited to MYC and BCL2 genes (Xenopus tropicalis)


name: ubiquinone-8 + (S)-malate <=> ubiquinol-8 + oxaloacetate


name: L-proline(out) + Na(+)(out) => L-proline(in) + Na(+)(in)


name: 3-hydroxyoctadecanoate + reduced [NADPH--hemoprotein reductase] + O2 => 3,18-dihydroxyoctadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Translocation of ERBB4s80 to the nucleus (Danio rerio)


name: (2E)-butenoyl-[ACP] + AMP + diphosphate => (2E)-2-butenoate + holo-[ACP] + ATP


name: Active p38 MAPK phosphorylates MAPKAPK2 or 3 (Mus musculus)


name: ALKBH8 methylates 5-carboxymethyluridine-34 in tRNA(Arg) and tRNA(Glu) yielding 5-methoxycarbonylmethyluridine-34 (Homo sapiens)


name: Active FLT3 binds to SOCS6 (Canis familiaris)


name: 1-tetradecanoylglycerol + H2O <=> tetradecanoate + glycerol + H(+)


name: 3 a ubiquinol(in) + nitrite(out) + 2 H(+)(out) <=> 3 a ubiquinone(in) + NH4(+)(out) + 2 H2O(out)


name: NTP Binds Active Site of RNA Polymerase II (Homo sapiens)


name: hyodeoxycholate + UDP-alpha-D-glucuronate => hyodeoxycholate 6-O-(beta-D-glucuronate) + UDP + H(+)


name: 2-oxobutanoate + L-phenylalanine <=> (2S)-2-aminobutanoate + 3-phenylpyruvate


name: PTPN4 gene expression is stimulated by MECP2 (Homo sapiens)


name: SMC5-SMC6 Complex SUMOylates Cohesin with SUMO1 (Sus scrofa)


name: L-threonyl-[protein] + UTP => uridylyl-L-threonyl-[protein] + diphosphate


name: Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Xenopus tropicalis)


name: 3-dehydro-6alpha-hydroxy-28-norteasterone + reduced [NADPH--hemoprotein reductase] + O2 = 6-dehydro-28-norteasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: N-(aminomethyl)urea + H2O <=> N-(hydroxymethyl)urea + NH4(+)


name: hydrolase activity, acting on acid phosphorus-nitrogen bonds


name: RAB5 GEFs exchange GTP for GDP on RAB5 (Caenorhabditis elegans)


name: mucilage biosynthetic process involved in seed coat development


name: 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ADP => 1D-myo-inositol hexakisphosphate + ATP


name: ZFPM proteins bind GATA proteins (Homo sapiens)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Xenopus tropicalis)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: SUMOylation of XPC with SUMO1 (Schizosaccharomyces pombe)


name: (S)-2-amino-6-oxohexanoyl-[protein] + (7R,8S)-8-amino-7-(carboxyamino)nonanoate + NADH + 3 H(+) => N(6)-[(2S,3R)-2-amino-8-carboxyoctan-3-yl]-L-lysyl-[protein] + CO2 + NAD(+) + H2O


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = a 2-acyl-sn-glycero-3-phospho-L-serine + 1-O-acyl-N-(acetyl)-sphing-4-enine


name: COQ6 hydroxylates DHB (Drosophila melanogaster)


name: PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Bos taurus)


name: PPP3 complex dephosphorylates DARPP-32 on Thr34 (Homo sapiens)


name: NPAS4 represses INS gene expression (Homo sapiens)


name: beta-catenin is replaced by repression complexes at the promoter (Mus musculus)


name: 3-lyso-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + 1-(9Z-octadecenoyl)-sn-glycerol <=> 3-(9Z-octadecenoyl)-sn-glycero-1-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + glycerol


name: 1,2-di-(9Z-octadecenoyl)-glycerol + H2O <=> 2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H(+)


name: Co(I)-[methylated-thiol-specific corrinoid protein] + methanethiol <=> methyl-Co(III)-[methylated-thiol-specific corrinoid protein] + hydrogen sulfide


name: NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Bos taurus)


name: steviolmonoside + UDP-alpha-D-glucose => rubusoside + UDP


name: regulation of membrane associated actin binding


name: inosine in double-stranded RNA + NH4(+) => adenosine in double-stranded RNA + H2O + H(+)


name: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2 => isochorismate + 2-oxoglutarate + H(+)


name: RHOD translocates to the Golgi membrane (Sus scrofa)


name: CK2 phosphorylates condensin I subunits (Drosophila melanogaster)


name: MRN complex bound to shortened telomeres recruits ATM (Canis familiaris)


name: mTORC1 phosphorylates MAF1 (Mus musculus)


name: PDPK1 (PDK1) phosphorylates PKN2 on threonine-816 (Saccharomyces cerevisiae)


name: 1,2-didecanoylglycerol + H2O => decanoylglycerol + decanoate + H(+)


name: 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + H2O = 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + a fatty acid + H(+)


name: pyrazinamide + H2O <=> pyrazine-2-carboxylate + NH4(+)


name: USP13 deubiquitinates BECN1,USP10 (Schizosaccharomyces pombe)


name: 3',3',3'-c-tri-AMP + 3 diphosphate => 3 ATP


name: (9Z)-octadecenoyl-CoA + A + 2 H2O => octadecanoyl-CoA + AH2 + O2


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (Mus musculus)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)


name: all-trans-5,6-epoxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2


name: NEIL1,NEIL2 recruits POLB to incised AP site (Mus musculus)


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Caenorhabditis elegans)


name: 2,3-dihydroxybenzenesulfonate + NH4(+) + NAD(+) => 2-aminobenzenesulfonate + NADH + O2 + 2 H(+)


name: Release of GABA at the synapse (Sus scrofa)


name: TFAP2B homodimer binds YEATS4 (Canis familiaris)


name: all-trans-4-hydroxyretinol + NAD(+) <=> all-trans-4-hydroxyretinal + NADH + H(+)


name: PTPN11 dephosphorylates RUNX1 (Homo sapiens)


name: serotonin + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA <=> N-[(5Z,8Z,11Z,14Z)-eicosatetraenoyl]-serotonin + CoA + H(+)


name: Activated FGFR4:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Caenorhabditis elegans)


name: TRIBOA beta-D-glucoside + S-adenosyl-L-methionine <=> DIMBOA beta-D-glucoside + S-adenosyl-L-homocysteine + H(+)


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Xenopus tropicalis)


name: Formation of NR-MED1 Coactivator Complex (Canis familiaris)


name: protochlorophyllide b + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O => protochlorophyllide a + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 5 H(+)


name: CYP19A1 binds Aromatase inhibitors (Drosophila melanogaster)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Gallus gallus)


name: ASPA deacetylates NAASP to acetate and L-aspartate (Mus musculus)


name: ATM phosphorylates TP53BP1 at DNA DSBs (Homo sapiens)


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Saccharomyces cerevisiae)


name: G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Sus scrofa)


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Saccharomyces cerevisiae)


name: Monoubiquitinated PTEN translocates to the nucleus (Dictyostelium discoideum)


name: Activated FGFR4 binds FRS2 (Canis familiaris)


name: (20S)-ginsenoside Rd + UDP + H(+) => (20S)-ginsenoside F2 + UDP-alpha-D-glucose


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) <=> a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out)


name: 4-hydroxy-3-methoxy-5-(all-trans-octaprenyl)benzoate + H(+) => 2-methoxy-6-(all-trans-octaprenyl)phenol + CO2


name: L-cystine(out) + L-aspartate(in) => L-cystine(in) + L-aspartate(out)


name: 7alpha-hydroxycholesterol is oxidized and isomerized to 4-cholesten-7alpha-ol-3-one (Danio rerio)


name: MBTPS1,2 cleaves CREB3L3 to CREB3L3(1-?) and CREB3L3(?-461) (Homo sapiens)


name: N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA => N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA


name: [(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate + NADP(+) = [4-(6-methylheptanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate + NADPH + H(+)


name: Proto-Oncogene Tyrosine-Protein Kinase ROS1 Inhibitors [MoA]


name: AURKB phosphorylates TP53 (Drosophila melanogaster)


name: ANGPTL8 binds ANGPTL3 (Canis familiaris)


name: SARM binds viral dsRNA:TLR3:TICAM1 (Homo sapiens)


name: Dimethyl fumarate modifies Cys191 in GSDMD (Sus scrofa)


name: negative regulation of citrulline biosynthetic process


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Caenorhabditis elegans)


name: L,L-cystathionine + phosphate => O-phospho-L-homoserine + L-cysteine


name: Co(I)-[methanol-specific corrinoid protein] + methanol + H(+) <=> methyl-Co(III)-[methanol-specific corrinoid protein] + H2O


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Canis familiaris)


name: cetraxate + benzyl alcohol + H(+) => benzyl cetraxate + H2O


name: N-acetyl-D-galactosamine 6-phosphate + H2O = D-galactosamine 6-phosphate + acetate


name: NOX2 generates superoxide anion from oxygen (Bos taurus)


name: naphthalene-1,3,6,8-tetrol + 5 CO2 + 5 CoA + H2O => 5 malonyl-CoA + 5 H(+)


name: 1-O-octadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: 3-(2,3-dihydroxyphenyl)propanoate + NAD(+) + H2O => 3-(2-hydroxyphenyl)propanoate + NADH + O2 + H(+)


name: L-phenylalanine + acetyl-CoA <=> N-acetyl-L-phenylalanine + CoA + H(+)


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Xenopus tropicalis)


name: 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 <=> 2-glyceryl-prostaglandin G2


name: pyrophosphate + H2O => 2 orthophosphate [mitochondrial] (Sus scrofa)


name: alpha-D-glucose 1-phosphate => alpha-D-glucose 6-phosphate


name: Phosphorylation and inactivation of eEF2K by activated S6K1 (Canis familiaris)


name: (indol-3-yl)acetyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+) => indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA


name: S-methyl-(E)-thiourocanate + H2O = S-methyl-thiohydantoin-5-propanoate


name: octan-1-ol + NAD(+) = octanal + NADH + H(+)


name: (3R)-3-hydroxy-4-oxobutanoate + NAD(+) + H2O = (R)-malate + NADH + 2 H(+)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Rattus norvegicus)


name: N-acetyl-alpha-D-muramate 1-phosphate + UDP + H(+) = UDP-N-acetyl-alpha-D-muramate + phosphate


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Rattus norvegicus)


name: nitrate(in) + 2 Na(+)(in) => nitrate(out) + 2 Na(+)(out)


name: sucrose 6(F)-phosphate + H2O = beta-D-fructose + beta-D-glucose 6-phosphate


name: pyridoxal 5'-phosphate + H2O2 + NH4(+) => pyridoxamine 5'-phosphate + O2 + H2O


name: a sterol ester + H2O <=> a sterol + a fatty acid + H(+)


name: (2R)-2-phosphoglycerate + ATP <=> (2R)-2,3-bisphosphoglycerate + ADP + H(+)


name: 16S rRNA (guanine(1207)-N(2))-methyltransferase activity


name: pentan-3-one + NADP(+) <=> pent-1-en-3-one + NADPH + H(+)


name: 1-O-(9Z-octadecenyl)-glycerol + (9Z)-octadecenoyl-CoA = 1-O-(9Z-octadecyl)-3-(9Z-octadecenoyl)-glycerol + CoA


name: SOS binds Grb2 bound to pFAK:NCAM1 (Bos taurus)


name: (2E,6E)-farnesyl diphosphate => alpha-cadinene + diphosphate


name: (R)-piperazine-2-carboxamide + H2O => (R)-piperazine-2-carboxylate + NH4(+)


name: SHP2 binds to the active receptor (Bos taurus)


name: 27-hydroxysterol binds ESR1, ESR2 (Sus scrofa)


name: PKC-delta is activated (Dictyostelium discoideum)


name: 1-propanol + acetyl-CoA = propyl acetate + CoA


name: L-aspartate + NH4(+) + ATP => L-asparagine + ADP + phosphate + H(+)


name: Active ARF recruits coatomer to the Golgi (Saccharomyces cerevisiae)


name: deoxycholate + NADP(+) = 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NADPH + H(+)


name: CAK-mediated phosphorylation of Cyclin E:Cdk2 (Drosophila melanogaster)


name: ATF7IP:SETDB1 binds SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin (Rattus norvegicus)


name: (S)-reticuline + reduced [NADPH--hemoprotein reductase] + O2 => 1,2-dehydroreticuline + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: atRAL(membrane) diffuses to atRAL(cytosol) (Homo sapiens)


name: a plastoquinone + an L-alpha-amino acid + H2O <=> a plastoquinol + a 2-oxocarboxylate + NH4(+)


name: MTMR4 binds phosphorylated SMAD2/3 (Canis familiaris)


name: RLBP1:11cRAL dissociates (Drosophila melanogaster)


name: Increased Striated Muscle Dynorphin Activity


name: IL4:IL4R:JAK2 binds IL2RG:JAK3 (Bos taurus)


name: positive regulation of Taq DNA polymerase


name: Surface deployment of platelet alpha granule membrane components (Xenopus tropicalis)


name: HSPA8:Substrate binds LAMP2a (Homo sapiens)


name: Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Canis familiaris)


name: 2 reduced [2Fe-2S]-[putidaredoxin] + (1R,4R)-camphor + O2 + 2 H(+) <=> (1R,4R,5R)-5-hydroxycamphor + 2 oxidized [2Fe-2S]-[putidaredoxin] + H2O


name: pexidartinib-resistant FLT3 mutants don't bind pexidartinib (Homo sapiens)


name: guanosine(46) in tRNA + S-adenosyl-L-methionine <=> N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine


name: Rap1 sequesters Raf1 to inhibit ERK cascade (Caenorhabditis elegans)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)


name: Transphosphorylation of pLIMK1 (Gallus gallus)


name: pentanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxoheptanoyl-[ACP] + CO2 + CoA


name: 1,2-di-(9Z-octadecenoyl)-sn-glycerol + hexadecanoyl-CoA => 1,2-di-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + CoA


name: Ubiquitinated RNF41 binds P-USP8 (Homo sapiens)


name: (2E)-3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)prop-2-enoate + NAD(+) => (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + NADH + H(+)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + (9Z,12Z)-octadecadienoyl-CoA <=> 1-O-hexadecyl-2-acetyl-3-(9Z,12Z)-octadecadienoyl-sn-glycerol + CoA


name: ADP and Pi bind to ATPase (Rattus norvegicus)


name: CEBPB and phospho-STAT3 bind the promoter of the MYC gene (Homo sapiens)


name: CDP(in) + UTP(out) => CDP(out) + UTP(in)


name: nicotinate beta-D-ribonucleotide + phenol = phenyl 5-phospho-alpha-D-ribofuranoside + nicotinate + H(+)


name: DAG is hydrolyzed to 2-MAG by PNPLA2/3 (Sus scrofa)


name: Decreased Smooth Muscle Epinephrine Activity


name: PROT mediates L-proline uptake (Rattus norvegicus)


name: 3-(4-hydroxyphenyl)pyruvate + CO2 + NADH => prephenate + NAD(+)


name: a N(6)-methylcarbamoyl-2'-deoxyadenosine in DNA + A + CoA + 2 H2O + H(+) => a 2'-deoxyadenosine in DNA + acetyl-CoA + AH2 + NH4(+) + O2


name: (R)-mandelate + NAD(+) => phenylglyoxylate + NADH + H(+)


name: adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine <=> 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine


name: (S)-(2E,6E,10E)-epoxygeranylgeranyl-triacetate lactone + A + H2O => (2E,6E,10E)-geranylgeranyl-triacetate lactone + AH2 + O2


name: 24-methylidenelophenol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> 4alpha-hydroxymethyl-ergosta-7,24(24(1))-dien-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: dihydrophloroglucinol + H2O => (S)-3-hydroxy-5-oxohexanoate


name: DOCK180:ELMO binds CRK (Xenopus tropicalis)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Mus musculus)


name: PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by cytosolic PLC[2] at the plasma membrane (Schizosaccharomyces pombe)


name: L-fucono-1,5-lactone + NADPH + H(+) => beta-L-fucose + NADP(+)


name: HDAC4 SUMOylates NR1H2 (LXRbeta) with SUMO2,3 (Rattus norvegicus)


name: WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Rattus norvegicus)


name: REV1 inserts dCMP opposite to AP sites in DNA (Canis familiaris)


name: prostaglandin E1(in) + ATP + H2O => prostaglandin E1(out) + ADP + phosphate + H(+)


name: Increased Enteric Nervous System Brain Derived Neurotropic Activity


name: down regulation of protein phosphatase 2 activity


name: Transphosphorylation of pLIMK1 (Sus scrofa)


name: (2R,4S)-ketoconazole(in) + ATP + H2O = (2R,4S)-ketoconazole(out) + ADP + phosphate + H(+)


name: succinate semialdehyde + NADPH + H(+) => 4-hydroxybutanoate + NADP(+)


name: 2 oxidized [amicyanin] + methylamine + H2O <=> 2 reduced [amicyanin] + formaldehyde + NH4(+) + 2 H(+)


name: nitric oxide dioxygenase NAD(P)H activity


name: PE is hydrolyzed to 2-acyl LPE by PLA2G4C (Danio rerio)


name: di-trans,nona-cis-dodecaprenyl phosphate + UDP-alpha-D-galacturonate <=> beta-D-galacturonosyl di-trans,nona-cis-dodecaprenyl phosphate + UDP


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Gallus gallus)


name: Activated ATM phosphorylates ABL1 (Bos taurus)


name: TRPC1 translocates calcium from the extracellular region to the cytosol (Drosophila melanogaster)


name: Autocatalytic activation of MMP7 (Gallus gallus)


name: IL34 dimer binds SDC1 (Xenopus tropicalis)


name: I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Homo sapiens)


name: PICALM binds R-SNAREs (Caenorhabditis elegans)


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Danio rerio)


name: 4-methyl-2-oxopentanoate + NAD(+) + CoA <=> 3-methylbutanoyl-CoA + CO2 + NADH


name: Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Gallus gallus)


name: L-phenylalanyl-L-histidine + angiotensin-(1-7) => angiotensin-(1-9) + H2O


name: 2alpha-hydroxytaxusin + reduced [NADPH--hemoprotein reductase] + O2 => 2alpha,7beta-dihydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Defective MUTYH mutants do not bind adenine mispaired with 8-oxoguanine (Homo sapiens)


name: Formation of AT-AC C complex (Rattus norvegicus)


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Canis familiaris)


name: D-glycero-D-manno-heptose 1,7-bisphosphate + H2O = D-glycero-D-manno-heptose 1-phosphate + phosphate


name: 3,6-anhydro-alpha-L-galactopyranose + NADP(+) + H2O = 3,6-anhydro-L-galactonate + NADPH + 2 H(+)


name: Serum albumin binds 2-lysophosphatidylcholine (Mus musculus)


name: MPST transfers sulfur from 3MPYR to HCN to form HSCN (Dictyostelium discoideum)


name: malonyl-CoA + AMP + diphosphate => malonate + ATP + CoA


name: Reactive oxygen species oxidize DNAJA1 (Plasmodium falciparum)


name: sitosterol + NADPH + O2 + H(+) => stigmasterol + NADP(+) + 2 H2O


name: RAC3 binds effectors at the plasma membrane (Caenorhabditis elegans)


name: p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 (Bos taurus)


name: urea + spermidine => N(1)-(3-aminopropyl)agmatine + H2O


name: PE is hydrolyzed to 1-acyl LPE by PLA2[16] (Homo sapiens)


name: 4-methylcyclohexanone + NH4(+) + NADPH + H(+) => 4-methyl-cyclohexylamine + NADP(+) + H2O


name: RNA Polymerase III Termination and release of transcribed RNA (Homo sapiens)


name: Conversion of Glycerol to Glycerol-3-phosphate (Xenopus tropicalis)


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O => 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Homo sapiens)


name: SLC2A9 transports Fru, Glc, urate (Drosophila melanogaster)


name: Recruitment of GRB2 to p-PTK2 (Sus scrofa)


name: gibberellin A12 aldehyde + A + H2O = gibberellin A12 + AH2 + H(+)


name: Cleavage of cytosine glycol by NTHL1 glycosylase (Caenorhabditis elegans)


name: 3-chloro-D-alanine <=> 2-aminoprop-2-enoate + chloride + H(+)


name: an (8Z,11Z,14Z)-icosatrienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Binding of TFIIE to the growing preinitiation complex (Saccharomyces cerevisiae)


name: D-maltotriono-1,5-lactone + H2O => D-maltotrionate + H(+)


name: SLC25A32 transports THF from cytosol to mitochondrial matrix (Dictyostelium discoideum)


name: positive regulation of ATP citrate synthase activity


name: an acyl-CoA(out) + ATP + H2O => an acyl-CoA(in) + ADP + phosphate + H(+)


name: xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate (Caenorhabditis elegans)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Canis familiaris)


name: ATR phosphorylates RPA2 (Caenorhabditis elegans)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Caenorhabditis elegans)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 => 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: phosphoethanolamine + 3 S-adenosyl-L-methionine <=> phosphocholine + 3 S-adenosyl-L-homocysteine + 3 H(+)


name: ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Homo sapiens)


name: Dynamin is recruited to the gap junction plaque (Homo sapiens)


name: α1-agonists bind ADRA1A,B,D (Danio rerio)


name: novobiocin(in) + H(+)(out) <=> novobiocin(out) + H(+)(in)


name: (3R)-hydroxydocosanoyl-CoA + NAD(+) <=> 3-oxodocosanoyl-CoA + NADH + H(+)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Drosophila melanogaster)


name: 6,6-kestotetraose + beta-D-glucose => 6-kestotriose + sucrose


name: acetylcholine(out) + 2 H(+)(in) = acetylcholine(in) + 2 H(+)(out)


name: AP-1 stimulates transcription of IGFBP7 (Homo sapiens)


name: LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST (Caenorhabditis elegans)


name: PDE6D binds S-Farn-Me KRAS4B:CALM:4 Ca2+ (Rattus norvegicus)


name: SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Homo sapiens)


name: cyclo-acetoacetyl-L-tryptophan + dimethylallyl diphosphate <=> beta-cyclopiazonate + diphosphate


name: a long-chain fatty acid(in) => a long-chain fatty acid(out)


name: (S)-malate + a quinone <=> a quinol + oxaloacetate


name: Excision of 8-oxoguanine by OGG1 glycosylase (Saccharomyces cerevisiae)


name: 7-O-methylcoclaurine + S-adenosyl-L-homocysteine + H(+) => isococlaurine + S-adenosyl-L-methionine


name: (S)-2,3-dihydrodipicolinate + 2 H2O + H(+) => L-aspartate 4-semialdehyde + pyruvate


name: N-hexacosenoylsphinganine + CoA + H(+) => hexacosenoyl-CoA + sphinganine


name: DAG and Ca+2 bind to PKC and tether it to membrane (Homo sapiens)


name: CaMKK autophosphorylates in the cytosol (Rattus norvegicus)


name: phenol + NADH + O2 + H(+) => hydroquinone + NAD(+) + H2O


name: XDH dehydrogenates xanthine to form urate (Caenorhabditis elegans)


name: misfolded CFTR is degraded by the 26S proteasome (Mus musculus)


name: C1-Inh binds and inactivates C1r, C1s (Rattus norvegicus)


name: (6R)-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) => 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H(+)


name: beta-D-fructose 1,6-bisphosphate => D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate


name: (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O <=> (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA


name: 3-phenylpropanoate + S-adenosyl-L-methionine <=> 3-phenylpropanoic acid methyl ester + S-adenosyl-L-homocysteine


name: 2-hydroxyisobutanoyl-CoA + L-lysyl-[protein] => N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + CoA + H(+)


name: STAMBPL1 is a deubiquitinase (Drosophila melanogaster)


name: BH2 binding can lead to eNOS uncoupling (Mus musculus)


name: ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Schizosaccharomyces pombe)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C3) (Drosophila melanogaster)


name: IL20:IL20RA:JAK1:IL20RB binds JAK2,JAK3 (Rattus norvegicus)


name: SAR1 Activation And Membrane Binding (Bos taurus)


name: type 2 cysteinyl leukotriene receptor ligand


name: (4R,7R)-4-isopropenyl-7-methyloxepan-2-one + NADP(+) + H2O => (1R,4R)-dihydrocarvone + NADPH + O2 + H(+)


name: 13,14-dihydro-15-oxo-PGF2alpha + NADP(+) => 15-oxoprostaglandin F2alpha + NADPH + H(+)


name: 2,6-dimethylheptanoyl-CoA + H2O => 2,6-dimethylheptanoate + CoA + H(+)


name: 26Sproteasome degrades K48polyUb-NIK (Gallus gallus)


name: EPM2A dimer dephosphorylates phosphoglycogen-GYG1 (Mus musculus)


name: a ganglioside GD1a (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside GalNAc-GD1a (d18:1(4E)) + UDP + H(+)


name: NAD(+) => cyclic ADP-beta-D-ribose + nicotinamide + H(+)


name: (3R)-3-isopropenyl-6-oxoheptanoate + NADP(+) + H2O => (1S,4R)-1-hydroxylimonen-2-one + NADPH + O2


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Homo sapiens)


name: (1S,4R)-2-(C-substituted-aminomethyl)-4-acyl-2-thiazoline-[protein] + O2 <=> (S)-2-(C-substituted-aminomethyl)-4-acyl-1,3-thiazole-[protein] + H2O2


name: L-asparagine(out) + chloride(out) + 2 Na(+)(out) <=> L-asparagine(in) + chloride(in) + 2 Na(+)(in)


name: ZDHCC8 transfers PALM from PALM-CoA to ABCA1 tetramer (Homo sapiens)


name: L-asparagine + glycine => glycyl-L-asparagine + H2O


name: Autophagosome maturation (Schizosaccharomyces pombe)


name: HNP1-4 are stored in primary neutrophil granules (Homo sapiens)


name: (2R)-3-sulfopropanediol + 2 NAD(+) + H2O => (2R)-3-sulfolactate + 2 NADH + 3 H(+)


name: Tyrosine phosphorylation of PRLR (Homo sapiens)


name: positive regulation of receptor activity in another organism


name: 1-deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) activity


name: AKT1 E17K mutant phosphorylates caspase-9 (Homo sapiens)


name: DYSF, CAV3 and TRIM72 bind (Homo sapiens)


name: an N-aryl-1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine + H2O => an N-aryl-1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)


name: dolabradiene + reduced [NADPH--hemoprotein reductase] + O2 <=> 15,16-epoxydolabrene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (10S)-hydroxy-(12Z)-octadecenoate => (9Z,12Z)-octadecadienoate + H2O


name: VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Caenorhabditis elegans)


name: (E)-sinapoyl-AMP + CoA <=> (E)-sinapoyl-CoA + AMP + H(+)


name: 7-carboxymellein + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+) => 7-methylmellein + 3 reduced [NADPH--hemoprotein reductase] + 3 O2


name: 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate + NAD(+) + H2O <=> 3-dehydroquinate + NH4(+) + NADH + H(+)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Rattus norvegicus)


name: butanoate + ATP + NADPH + H(+) <=> butanal + AMP + diphosphate + NADP(+)


name: ELOVL3,6,7 elongate PALM-CoA and Mal-CoA to 3OOD-CoA (Dictyostelium discoideum)


name: NEDD8-UBA3:NAE1 binds a second NEDD8 (Rattus norvegicus)


name: Recruitment of CBL to KIT (Homo sapiens)


name: menaquinol-4 + diphosphate => menadiol + (2E,6E,10E)-geranylgeranyl diphosphate


name: "Kdo2-lipid A phosphoethanolamine 7''-transferase"


name: (2S,9S)-annullatin H + 2 A <=> (2S,9S)-annullatin D + 2 AH2


name: 1-naphthaldehyde + O2 + H2O <=> 1-naphthoate + H2O2 + H(+)


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Homo sapiens)


name: NEIL3 D132V does not cleave 5-guanidinohydantoin (Gh) (Homo sapiens)


name: tetradecanoyl-CoA + acetyl-CoA <=> 3-oxohexadecanoyl-CoA + CoA


name: Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Sus scrofa)


name: Phosphorylation of SHC1 by ERBB4 homodimers (Mus musculus)


name: Ac-PTGS2 dimer oxidises DHA to 17(R)-Hp-DHA (Canis familiaris)


name: taurine + A + H2O = sulfoacetaldehyde + AH2 + NH4(+)


name: laricitrin + S-adenosyl-L-homocysteine + H(+) => myricetin + S-adenosyl-L-methionine


name: (E,E)-piperate + ATP + CoA = (E,E)-piperoyl-CoA + AMP + diphosphate


name: activation of 5-methyltetrahydrofolate:NADP(+) oxidoreductase activity


name: 4-(gamma-L-glutamylamino)butanal + NADP(+) + H2O <=> 4-(gamma-L-glutamylamino)butanoate + NADPH + 2 H(+)


name: SMG6 hydrolyzes mRNA with premature termination codon (Bos taurus)


name: RAC2 binds effectors at the ER membrane (Rattus norvegicus)


name: N-octadecanoylsphing-4-enine + D-galactose => beta-D-galactosyl-(1<->1')-N-octadecanoylsphing-4-enine + H2O


name: (3S)-hydroxyeicosanoyl-CoA => (2E)-eicosenoyl-CoA + H2O


name: a 1-O-(9Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a 1-O-(1Z,9Z-octadecadienyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: Monoiodinated tyrosine can be deiodinated (Danio rerio)


name: POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Sus scrofa)


name: PP2A-PP2R5C dephosphorylates MDM2 (Bos taurus)


name: CR1 binds C3bBb/C4bC2a (Canis familiaris)


name: (3S)-citramalyl-CoA <=> 3-methylfumaryl-CoA + H2O


name: NR3C2 binds fludrocortisone (Plasmodium falciparum)


name: HRH3 binds pitosilant (Caenorhabditis elegans)


name: MDM2 ubiquitinates phosphorylated MDM4 (Rattus norvegicus)


name: ENPEP:Zn2+ hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8) (Drosophila melanogaster)


name: hexan-3-one + NADPH + O2 + H(+) = ethyl butanoate + NADP(+) + H2O


name: activation of adenosylcobalamin-dependent ribonucleotide reductase activity


name: 5-hydroxyisourate + H2O <=> 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)


name: Hemes bind to BACH1:MAFK (Canis familiaris)


name: (2E,6E,10E,14E)-geranylfarnesol + H2O => (17E)-cheilanthenediol


name: β1-agonists bind ADRB1 (Rattus norvegicus)


name: Sequestration of BAD protein by 14-3-3 (Homo sapiens)


name: MARC1,MARC2 reduce N-hydroxylated compounds (Drosophila melanogaster)


name: (2E,6E)-farnesoate + S-adenosyl-L-methionine => methyl (2E,6E)-farnesoate + S-adenosyl-L-homocysteine


name: 1-(9Z-octadecenoyl)-sn-glycerol + phosphocholine + H(+) => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O


name: endothelial nitric-oxide synthase biosynthetic process


name: Activated NOD2 oligomerizes (Canis familiaris)


name: PIAS1 SUMOylates NR2C1 (TR2) (Homo sapiens)


name: Expression of GLI1 is repressed by GLI3R in the absence of Hh signaling (Homo sapiens)


name: SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Rattus norvegicus)


name: Mature HBEGF binds to EGFR, triggering dimerisation and autophosphorylation of the receptor (Rattus norvegicus)


name: fibroblast growth factor receptor signaling pathway involved in type I programmed cell death


name: cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Rattus norvegicus)


name: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose (Homo sapiens)


name: chlorophyllide a + H2O + H(+) <=> 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d + methanol + CO2


name: Parkin transfers Ub to misfolded proteins (Drosophila melanogaster)


name: N-(2-methylpropyl)hydroxylamine + FAD + H2O + 2 H(+) => 2-methylpropan-1-amine + FADH2 + O2


name: SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Plasmodium falciparum)


name: 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ (Canis familiaris)


name: Increased Immunologically Active Biogenic Amine Activity


name: Integrin alpha6beta1 binds laminin-322, 512, 521, 211, 221, 411 (Homo sapiens)


name: prestrychnine + H(+) = isostrychnine + CO2 + H2O


name: MITF-M dimer binds the TBX2 gene (Homo sapiens)


name: L-phenylalanine + (9Z)-octadecenoate => N-(9Z-octadecenoyl)-L-phenylalanine + H2O


name: (-)-4'-desmethyl-deoxypodophyllotoxin + reduced [NADPH--hemoprotein reductase] + O2 = 4'-demethylepipodophyllotoxin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: L-lysine + 2-oxoglutarate + NADPH + H(+) => L-saccharopine + NADP(+) + H2O


name: (15S)-hydroperoxy-(11Z,13E)-eicosadienoate + 2 glutathione => (15S)-hydroxy-(11Z,13E)-eicosadienoate + glutathione disulfide + H2O


name: (5S)-hydroperoxy-(18R)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate + AH2 = resolvin E2 + A + H2O


name: Transphosphorylation of pLIMK1 (Bos taurus)


name: p-S225-SPHK1 localizes to cytosol (Drosophila melanogaster)


name: 2,5-dioxopentanoate + NAD(+) + H2O => 2-oxoglutarate + NADH + 2 H(+)


name: beta-L-fucose 1-phosphate + GTP + H(+) = GDP-beta-L-fucose + diphosphate


name: bHEXA hydrolyzes GM2A:GM2 to GM2A:GM3 (Sus scrofa)


name: 2-hydroxyspirilloxanthin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 2,2-dihydroxyspirilloxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: all-trans-heptaprenyl diphosphate + 4-hydroxybenzoate <=> 4-hydroxy-3-(all-trans-heptaprenyl)benzoate + diphosphate


name: L-Glutamate binds GRM4 (mGluR4) (Homo sapiens)


name: glycine + 2 S-adenosyl-L-methionine => N,N-dimethylglycine + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: PAK1-3 dimer disassociates (Caenorhabditis elegans)


name: Initial activation of proMMP7 by trypsin (Danio rerio)


name: negative regulation of netrin-activated signaling pathway


name: 1,2,3-tri-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O <=> 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)


name: ABCC1 transports cytosolic RCbl to extracellular region (Drosophila melanogaster)


name: 1D-myo-inositol 2,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,5-triphosphate + phosphate


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Canis familiaris)


name: CDC42 and PIP2 bind WASL, activating it (Caenorhabditis elegans)


name: stimulation of protein phosphatase type 2A activity


name: CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Mus musculus)


name: a (2S)-2-hydroxycarboxylate + NAD(+) => a 2-oxocarboxylate + NADH + H(+)


name: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + (7,8-dihydropterin-6-yl)methyl diphosphate => N-[(7,8-dihydropterin-6-yl)methyl]-4-(beta-D-ribofuranosyl)aniline 5'-phosphate + diphosphate


name: DVL2 binds phosphorylated WWTR1 (TAZ) (Rattus norvegicus)


name: MAPK4,6 translocate to nucleus (Rattus norvegicus)


name: (2S)-2-amino-4-deoxychorismate + L-glutamine + H2O <=> 4-amino-4-deoxychorismate + L-glutamate + NH4(+)


name: Plk1-mediated phosphorylation of Nlp (Homo sapiens)


name: bisdemethoxycurcumin + CO2 + 2 CoA => (4-coumaroyl)acetyl-CoA + 4-coumaroyl-CoA + H2O


name: TFIIH binds GG-NER site to form a verification complex (Xenopus tropicalis)


name: 18-hydroxy-(9R,10S)-epoxy-octadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (9R,10S)-epoxy-octadecanoate + reduced [NADPH--hemoprotein reductase] + O2


name: Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Danio rerio)


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Saccharomyces cerevisiae)


name: Interaction of PECAM-1 and SHIP (Bos taurus)


name: (2E,6E)-farnesyl diphosphate <=> (-)-7-epi-alpha-selinene + diphosphate


name: Formation of VAF (virus-activated factor) complex (Bos taurus)


name: a 5'-end triphospho-(purine-ribonucleoside) in mRNA + H2O => a 5'-end diphospho-(purine-ribonucleoside) in mRNA + phosphate + H(+)


name: diphosphoric monoester hydrolase activity


name: prephenate + L-glutamate => L-arogenate + 2-oxoglutarate


name: 25(S) DHCA-CoA is dehydrogenated to 25(S) 3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA (Mus musculus)


name: N-hydroxylation of 4-aminobiphenyl (Homo sapiens)


name: Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome (Homo sapiens)


name: Phospho-Chico: Activated DINR binds p60:Dp110 (Drosophila melanogaster)


name: ANKH transports PPi from cytosol to extracellular region (Canis familiaris)


name: PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Sus scrofa)


name: cytoskeleton-nuclear membrane anchor activity


name: 2-deoxy-D-ribose 5-phosphate <=> D-glyceraldehyde 3-phosphate + acetaldehyde


name: Association of procollagen type IV (Homo sapiens)


name: L-proline + NAD(+) <=> 1-pyrroline-2-carboxylate + NADH + H(+)


name: 2 2-aminophenol + A + O2 = 2-aminophenoxazin-3-one + AH2 + 2 H2O


name: 1-tetradecanoyl-sn-glycerol 3-phosphate + H2O = 1-tetradecanoyl-sn-glycerol + phosphate


name: IGF1R phosphorylates SHC1 (Xenopus tropicalis)


name: an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol


name: 11-cis-retinol + a fatty acyl-CoA = 11-cis-retinyl ester + CoA


name: (20S)-ginsenoside Rb1 + 2 H2O <=> (20S)-ginsenoside Rg3 + 2 D-glucose


name: glyoxylate + L-aspartate => oxaloacetate + glycine


name: Recruitment of Grb2 to pFAK:NCAM1 (Caenorhabditis elegans)


name: HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Caenorhabditis elegans)


name: D-mannitol + NADP(+) <=> D-fructose + NADPH + H(+)


name: 3-oxo-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADPH + H(+) <=> (3R)-hydroxy-(19Z,22Z,25Z,28Z,31Z)-tetratriacontapentaenoyl-CoA + NADP(+)


name: CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Homo sapiens)


name: SULT1A1 dimer sulfonates NHABP (Xenopus tropicalis)


name: Phosphorylation of Platelet Sec-1 (Rattus norvegicus)


name: (2E,6E)-farnesyl diphosphate => aristolene + diphosphate


name: 3-oxo-(13Z)-eicosenoyl-CoA + CO2 + CoA => (11Z)-octadecenoyl-CoA + malonyl-CoA + H(+)


name: HMOX1 dimer, HMOX2 cleave heme (Xenopus tropicalis)


name: N,1-diacyl-sn-glycero-3-phosphoethanolamine + H2O => an N-acylethanolamine + a 1-acyl-sn-glycero-3-phosphate + H(+)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Bos taurus)


name: L-asparaginyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-asparaginyl-[ankyrin-repeat domain protein] + succinate + CO2


name: BRCA1 binds phosphorylated RBBP8 (Gallus gallus)


name: APC/C:Cdh1-mediated degradation of Skp2 (Dictyostelium discoideum)


name: a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA <=> 1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphoethanolamine + CoA


name: Decreased Muscular System Epinephrine Activity


name: mTORC1 binds RHEB:GTP (Xenopus tropicalis)


name: 1-tetradecanoylglycerol + (9Z)-octadecenoyl-CoA => 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + H2O <=> 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + octadecanoate + H(+)


name: hexadecanoyl-CoA + H2O => hexadecanoate + CoA + H(+)


name: a 2'-deoxyribonucleoside 5'-triphosphate + pyruvate <=> a 2'-deoxyribonucleoside 5'-diphosphate + phosphoenolpyruvate + H(+)


name: 3 H2 + 12 oxidized [2Fe-2S]-[ferredoxin] + 2 NH4(+) + 40 ADP + 40 phosphate + 26 H(+) => N2 + 12 reduced [2Fe-2S]-[ferredoxin] + 40 ATP + 40 H2O


name: 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate => sn-glycerol 1-phosphate + all-trans-heptaprenyl diphosphate


name: a monocarboxylate + NH4(+) => a monocarboxylic acid amide + H2O


name: Interaction of Tie2 and p85 of PI3K (Bos taurus)


name: beta-alanyl-L-ornithine + H2O <=> beta-alanine + L-ornithine


name: a (7S)-7-hydroxy-C2-C8-saturated long-chain fatty acyl-[ACP] + oxidized [flavodoxin] + H2O + H(+) => a C2-C8-saturated long-chain fatty acyl-[ACP] + reduced [flavodoxin] + O2


name: PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Drosophila melanogaster)


name: Formation of di-heterotetramers of GluN1 (GRIN1) and GluN3A (GRIN3A) (Homo sapiens)


name: Activated FGFR3:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Danio rerio)


name: 3-hydroxypyruvate + H2O2 + NH4(+) => L-serine + O2 + H2O


name: Proteasomal cleavage of substrate (Schizosaccharomyces pombe)


name: dopamine + S-adenosyl-L-methionine <=> 3-methoxytyramine + S-adenosyl-L-homocysteine + H(+)


name: activation of calcineurin-NFAT signaling cascade


name: 2-acyl LPC is acylated to PC by LPCAT (Danio rerio)


name: chorismate = 3-[(1-carboxyvinyl)-oxy]benzoate + H2O


name: positive regulation of lipid biosynthesis


name: ADP-ribosyl-[dinitrogen reductase] hydrolase activity


name: adenosine(in) + H(+)(in) = adenosine(out) + H(+)(out)


name: TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus (Rattus norvegicus)


name: ESTG binds ESR2:chaperone complex (Danio rerio)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Sus scrofa)


name: luciferyl sulfate + adenosine 3',5'-bisphosphate + H(+) => coelenterazine h + 3'-phosphoadenylyl sulfate


name: 9-(acyloxy)-octadecanoate + a 2-acylglycerol => 9-hydroxy-octadecanoate + a 1,2-diacyl-sn-glycerol


name: ethene + L-dehydroascorbate + hydrogen cyanide + CO2 + 2 H2O => 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2


name: 2',3'-cyclophospho-AMP + H2O <=> adenosine 2'-phosphate + H(+)


name: GRIN2B gene expression is inhibited by MECP2 (Homo sapiens)


name: N,N-dimethyl-cadaverine + 2,6,9-trimethyl-13-oxatetracyclo[6.3.1.1(6,9).0(1,5)]tridecane carbocation => pre-flavunoidine + H(+)


name: isomaltose + H2O => 2 D-glucose (sucrase-isomaltase) (Gallus gallus)


name: RANKL,sRANKL trimer binds RANK (Gallus gallus)


name: Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Mus musculus)


name: N-benzoylglycine + CoA + H(+) => benzoyl-CoA + glycine


name: D-ribulose 5-phosphate => D-xylulose 5-phosphate


name: MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG (Canis familiaris)


name: activation of hedgehog signaling pathway involved in dorsal/ventral neural tube patterning


name: MAOB inhibitors bind MAOB:FAD (Homo sapiens)


name: protein-phosphocysteine-glucose phosphotransferase system transporter activity


name: ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 (Homo sapiens)


name: Loading of PCNA - Sliding Clamp Formation (Mus musculus)


name: genistein + UDP-alpha-D-glucose <=> genistein 7-O-beta-D-glucoside + UDP + H(+)


name: Dopamine synaptic vesicle docking and priming (Mus musculus)


name: cortisol + acetyl-CoA <=> cortisol 21-acetate + CoA


name: protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Bos taurus)


name: 2,2',3-trihydroxydiphenyl ether + O2 + H(+) = 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate


name: O-phospho-L-threonyl-[protein] + H2O => L-threonyl-[protein] + phosphate


name: HTR1A binds HTR1A antagonists (Canis familiaris)


name: MARK3 phosphorylates MITF-M on S173 (Drosophila melanogaster)


name: WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Rattus norvegicus)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Canis familiaris)


name: 2xPDKX:2xZn2+ phosphorylates PDX (Saccharomyces cerevisiae)


name: PALM-C100-CKAP4 transports SFTPAs from extracellular region to lamellar body (Mus musculus)


name: phosphocholine + CTP + H(+) = CDP-choline + diphosphate


name: a 1,N(6)-etheno-2'-deoxyadenosine in double-stranded DNA + 2-oxoglutarate + O2 + H2O => a 2'-deoxyadenosine in double-stranded DNA + glyoxal + succinate + CO2


name: Cholesterol is hydroxylated to 25-hydroxycholesterol (Saccharomyces cerevisiae)


name: TGFBR3 binding to GIPC1 (Rattus norvegicus)


name: Calcium Influx through Voltage-gated Calcium Channels (Drosophila melanogaster)


name: Ca permeable AMPA receptor ligand binding (Sus scrofa)


name: CETP-mediated lipid exchange: LDL gains cholesterol ester (Gallus gallus)


name: spherical HDL and SR-BI receptor form a complex at the cell surface (Sus scrofa)


name: Regulation of KIF23 (MKLP1) by phosphorylation (Mus musculus)


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Rattus norvegicus)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 => 16(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a flavonol 3-O-beta-D-glucoside + malonyl-CoA => a flavonol 3-O-(6-O-malonyl-beta-D-glucoside) + CoA


name: a short-chain fatty aldehyde + NAD(+) + H2O => a short-chain fatty acid + NADH + 2 H(+)


name: cyclohexane-1-carboxylate + succinyl-CoA <=> cyclohexane-1-carbonyl-CoA + succinate


name: an (S)-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-methionine => an (S)-cis-N-methyl-7,8,13,14-tetrahydroprotoberberine + S-adenosyl-L-homocysteine


name: SLC45A3 transports Glc from extracellular region to cytosol (Gallus gallus)


name: activation of DNA catabolic process during apoptosis


name: 4-cholesten-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,24(S)-triol-3-one (Homo sapiens)


name: IRE1 binds IRE1 forming dimer (Canis familiaris)


name: HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Rattus norvegicus)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Plasmodium falciparum)


name: Addition of a bifurcating GlcNAc to the N-glycan by MGAT3 (Drosophila melanogaster)


name: Heterodimerization of CEACAMs (Homo sapiens)


name: TMED2:TMED10 tetramer binds GPI anchored proteins (Bos taurus)


name: LC3:ATG7 dimer binds ATG3 (Mus musculus)


name: RAB43 hydrolyses GTP (Schizosaccharomyces pombe)


name: 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate


name: CERT1-2 releases its bound ceramide into the membrane of the Golgi apparatus (Caenorhabditis elegans)


name: nocardicin C + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = 2'-N-hydroxynocardicin C + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: CDP-Cho and DAG are converted to PC by CHPT1 at the Golgi membrane (Saccharomyces cerevisiae)


name: Ubiquitination of DLL/JAG ligands upon binding to NOTCH1 HD+PEST domain mutants (Homo sapiens)


name: all-trans-beta-carotene + O2 = 2 all-trans-retinal


name: KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Sus scrofa)


name: Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol (Homo sapiens)


name: PTPN11 is phosphorylated (Xenopus tropicalis)


name: a thiol + S-adenosyl-L-methionine <=> a methyl thioether + S-adenosyl-L-homocysteine + H(+)


name: 9H-carbazole + NADH + O2 + H(+) => 2'-aminobiphenyl-2,3-diol + NAD(+)


name: (2S,4R)-ketoconazole(in) + ATP + H2O <=> (2S,4R)-ketoconazole(out) + ADP + phosphate + H(+)


name: [DsbA protein]-disulfide + [DsbB protein]-dithiol => [DsbB protein]-disulfide + [DsbA protein]-dithiol


name: 15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity


name: L-alaninol + L-glutamate => gamma-L-glutamyl-L-alaninol + H2O


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Saccharomyces cerevisiae)


name: CYP3A4 monooxygenates ATV to 4-OH-ATV (Danio rerio)


name: Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Drosophila melanogaster)


name: 1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Sus scrofa)


name: PLG(20-810) binds anti-fibrinolytics (Rattus norvegicus)


name: (S)-2-amino-6-oxohexanoate + L-glutamate + NADH + H(+) => L-saccharopine + NAD(+) + H2O


name: AK6 phosphorylates (d)NMPs to (d)NDPs (Dictyostelium discoideum)


name: Removal of RNA primer and dissociation of RPA and Dna2 (Homo sapiens)


name: Estrogen-responsive KDM4B gene expression (Homo sapiens)


name: NMDAR binds PSD-95 subfamily members (Homo sapiens)


name: pyridoxine 5'-phosphate + O2 = pyridoxal 5'-phosphate + H2O2


name: protodeoxyviolaceinate + NADH + 2 O2 + 2 H(+) = proviolacein + CO2 + NAD(+) + 2 H2O


name: Retromer associates with WLS (Canis familiaris)


name: 3,5-dichlorocatechol + NADP(+) + H2O => 2,4-dichlorophenol + NADPH + O2 + H(+)


name: BPI binds LPS on the bacterial surface (Dictyostelium discoideum)


name: PAK1-3 autophosphorylates (Gallus gallus)


name: ATPase-coupled monoatomic cation transmembrane transporter activity


name: TNF-α:TNFR1 binds DENN/MADD (Mus musculus)


name: CDP-D-ribose + diphosphate => D-ribose 5-phosphate + CTP + H(+)


name: pentanoyl-CoA + O2 <=> (2E)-pentenoyl-CoA + H2O2


name: inhibition of cytokinin oxidase activity


name: all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity


name: NLRP3 activation by small molecules (Mus musculus)


name: alpha,alpha-trehalose 6-phosphate + a ribonucleoside 5'-diphosphate + H(+) => a ribonucleoside 5'-diphosphate-alpha-D-glucose + D-glucose 6-phosphate


name: Phosphorylated MAPKs translocate into the nucleus (Bos taurus)


name: SUMOylation of NCOA1 with SUMO1 (Mus musculus)


name: p62 recruits an atypical PKC (Mus musculus)


name: 2,4-dimethylbenzyl alcohol + O2 => 2,4-dimethylbenzaldehyde + H2O2


name: PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Rattus norvegicus)


name: TDO tetramer dioxygenates L-Trp to NFK (Mus musculus)


name: 2-hydroxyethane-1-sulfonate = acetaldehyde + sulfite + H(+)


name: cholate + ATP + CoA = choloyl-CoA + AMP + diphosphate


name: ACE2(18-805):Zn2+ hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9) (Canis familiaris)


name: 5-methylcytidine(72) in tRNA(Cys) + S-adenosyl-L-homocysteine + H(+) => cytidine(72) in tRNA(Cys) + S-adenosyl-L-methionine


name: 3-dehydrocarnityl-CoA + CoA <=> N,N,N-trimethylglycyl-CoA + acetyl-CoA


name: ACE2 is glycosylated to glycosylated-ACE2 (Homo sapiens)


name: Association of procollagen type XX (Gallus gallus)


name: AGRN binds Beta amyloid fibril via GAG chains (Canis familiaris)


name: Expression of TBX5 in cardiogenesis (Homo sapiens)


name: BP180 interacts intracellularly with plectin and integrin beta4 (Homo sapiens)


name: 2'-deoxymugineate + 2-oxoglutarate + O2 = mugineate + succinate + CO2


name: 4-terpineol + diphosphate => (2E)-geranyl diphosphate + H2O


name: ISGylation of DDX58 (RIG-I) (Sus scrofa)


name: a di-trans,poly-cis-polyprenol + NADP(+) <=> a di-trans,poly-cis-polyprenal + NADPH + H(+)


name: Phosphorylation of CRMPs by Cdk5 (Sus scrofa)


name: dodecanoyl-CoA + O2 => (2E)-dodecenoyl-CoA + H2O2


name: anthranilate + NADPH + O2 + 2 H(+) = 2,3-dihydroxybenzoate + NH4(+) + NADP(+)


name: N(6),N(6)-dimethyl-L-lysyl-[citrate synthase] + S-adenosyl-L-homocysteine + H(+) => N(6)-methyl-L-lysyl-[citrate synthase] + S-adenosyl-L-methionine


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 = N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: N-terminal N(alpha)-acetyl-L-methionyl-L-seryl-[protein] + CoA + H(+) => N-terminal L-methionyl-L-seryl-[protein] + acetyl-CoA


name: activation of brain-derived neurotrophic factor receptor signaling pathway


name: BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Sus scrofa)


name: (9Z,12Z)-octadecadienoyl-CoA + 2 NADPH + 2 H(+) <=> (9Z,12Z)-octadecadien-1-ol + 2 NADP(+) + CoA


name: 1-O-methyl-20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 => 1-O-methyl-12-hydroperoxy-20-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: alpha-D-galacturonosyl-[(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n) + UDP-beta-L-rhamnose => [(1->2)-alpha-L-rhamnosyl-(1->4)-alpha-D-galacturonosyl](n+1) + UDP + H(+)


name: PARVB interacts with Alpha-actinin (Mus musculus)


name: acetoacetate + acetyl-CoA => (3S)-3-hydroxy-3-methylglutaryl-CoA


name: SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Homo sapiens)


name: 11cROL binds to RLBP1 to form RLBP1:11cROL (Dictyostelium discoideum)


name: PIAS1,2-1 SUMOylate HIC1 with SUMO1 (Homo sapiens)


name: pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Schizosaccharomyces pombe)


name: a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + adenosine 3',5'-bisphosphate + H(+) => a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + 3'-phosphoadenylyl sulfate


name: GLI3R translocates to the nucleus (Sus scrofa)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Sus scrofa)


name: malonate + ATP + CoA <=> malonyl-CoA + AMP + diphosphate


name: MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Canis familiaris)


name: phorbol 12,13-dibutanoate + H2O <=> phorbol 13-butanoate + butanoate + H(+)


name: a uridine in rRNA <=> a pseudouridine in rRNA


name: Translocation of STAT1 dimer to nucleus (Danio rerio)


name: KW2449-resistant FLT3 mutants don't bind KW2449 (Homo sapiens)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O <=> 1,3-dihexadecanoylglycerol + (9Z)-octadecenoate + H(+)


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Mus musculus)


name: (+)-7-isojasmonate + L-isoleucine => L-isoleucine-(+)-7-isojasmonate + H2O


name: cytidine + phosphate => cytidine 2'-phosphate + H2O


name: TXNIP binds reduced thioredoxin (Schizosaccharomyces pombe)


name: L-galactonate = 2-dehydro-3-deoxy-L-galactonate + H2O


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Drosophila melanogaster)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)


name: RUNX2:CBFB:p-Y-YAP1 binds the BGLAP gene promoter (Homo sapiens)


name: RHOQ GAPs stimulate RHOQ GTPase activity (Homo sapiens)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Mus musculus)


name: tricetin + S-adenosyl-L-methionine = 3'-O-methyltricetin + S-adenosyl-L-homocysteine + H(+)


name: shikimate(in) + H(+)(in) = shikimate(out) + H(+)(out)


name: Interaction of PECAM-1 and SHIP (Mus musculus)


name: gramine + 2 S-adenosyl-L-homocysteine + 2 H(+) => 3-(aminomethyl)indole + 2 S-adenosyl-L-methionine


name: xanthogalenol + S-adenosyl-L-methionine => 4'-O-methylxanthohumol + S-adenosyl-L-homocysteine + H(+)


name: Formation of the CTF18-RFC(7s) complex (Gallus gallus)


name: q-dihydrobiopterin + NADH + H+ => tetrahydrobiopterin + NAD+ (Xenopus tropicalis)


name: (1S,8aS)-octahydroindolizin-1-ol + CO2 + 3 NADP(+) + CoA + 2 H2O => L-pipecolate + malonyl-CoA + 3 NADPH + 5 H(+)


name: WNTs are secreted in exosomes (Gallus gallus)


name: Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10) (Bos taurus)


name: an L-alpha-amino acid + holo-[ACP] + ATP <=> an L-alpha-aminoacyl-[ACP] + AMP + diphosphate


name: Formation of RAD50:MRE11 complex (Homo sapiens)


name: chenodeoxycholate + D-glucose => beta-D-glucosyl-(1->3)-O-chenodeoxycholate + H2O


name: GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Canis familiaris)


name: PTGS1 dimer binds PTGS1 Inhibitors (Rattus norvegicus)


name: (2E)-tetracosenoyl-CoA + NADH + H(+) <=> tetracosanoyl-CoA + NAD(+)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: adenosine 5'-tetraphosphate + H2O => phosphate + ATP + H(+)


name: activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin (Mus musculus)


name: CYP17A1 cleaves 17aHPREG to DHA (Homo sapiens)


name: D2D3,4 bind to DA (Drosophila melanogaster)


name: 2 L-cysteine => L-lanthionine + hydrogen sulfide + H(+)


name: HAS1,2,3 mediate the polymerization of HA (Rattus norvegicus)


name: Degradation of multiubiquitinated cell cycle proteins (Homo sapiens)


name: 3-oxalomalate => oxaloacetate + glyoxylate


name: limonene-1,2-diol + NAD(+) = 1-hydroxylimonen-2-one + NADH + H(+)


name: stigmasterol + UDP-alpha-D-glucose => stigmasteryl 3-beta-D-glucoside + UDP + H(+)


name: Cathelicidin LL-37 binds to bacterial cell wall (Sus scrofa)


name: 20oh-LTB4 is oxidised to 20cho-LTB4 by CYP4F2/4F3 (Sus scrofa)


name: chorismate + NH4(+) <=> 4-amino-4-deoxychorismate + H2O


name: 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H(+) <=> 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)


name: ganglioside GA1 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate <=> ganglioside GM1 (d18:1(4E)/18:0) + CMP + H(+)


name: apo-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit] + (2R,3E)-phycocyanobilin => phycoviolobilin-L-cysteinyl(84)-[phycoerythrocyanin alpha-subunit]


name: an N-fatty-acyl-L-alpha-amino acid + H2O = an L-alpha-amino acid + a fatty acid


name: C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Canis familiaris)


name: positive regulation of transforming growth factor beta production


name: alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + H2O => alpha-D-ribose 1,5-bisphosphate + H(+)


name: N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+)


name: Dephosphorylation of CK2-modified condensin I (Plasmodium falciparum)


name: nonane-4,6-dione + H2O <=> pentan-2-one + butanoate + H(+)


name: 1-butyrylglycerol + H2O = butanoate + glycerol + H(+)


name: P2Y6 receptor can bind to UDP (Mus musculus)


name: (2S)-naringenin 4'-methyl ether + S-adenosyl-L-homocysteine + H(+) => (2S)-naringenin + S-adenosyl-L-methionine


name: 16-hydroxyhexadecanoate + NAD(+) = 16-oxohexadecanoate + NADH + H(+)


name: 3-beta-hydroxy-4-beta-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating) activity


name: ALOX12 oxidises LTA4 to LXA4 (Homo sapiens)


name: CREBBP acetylates HINT1 dimer (Mus musculus)


name: FGFR2b binds to FGF (Caenorhabditis elegans)


name: positive regulation of tatiopterin biosynthetic process


name: Trace amine-associated receptors can bind trace amines (Xenopus tropicalis)


name: O-sinapoylcholine + H2O = (E)-sinapate + choline + H(+)


name: PRDX1,2,5 catalyze TXN reduced + H2O2 => TXN oxidized + 2H2O (Plasmodium falciparum)


name: eicosanoyl-CoA + taurine = N-eicosanoyl-taurine + CoA + H(+)


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Rattus norvegicus)


name: a 5'-end diphospho-adenosine in mRNA + phosphate + H(+) => a 5'-end triphospho-adenosine in mRNA + H2O


name: p-AMPK:AMP binds the ULK complex (Canis familiaris)


name: Activation of STAT5a/b by JAK2 (Homo sapiens)


name: Active IRS recruits PI3K to the plasma membrane and activates it (Xenopus tropicalis)


name: a short-chain 3-oxoacyl-CoA + CoA => a short-chain fatty acyl-CoA + acetyl-CoA


name: CYP2A13 oxidises AFM1 to AFM1E (Drosophila melanogaster)


name: 3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-methionine = 4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)


name: RIPK1 is cleaved by CASP8:FLIP(L) (Sus scrofa)


name: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O


name: ACLY tetramer binds ETC-1002-CoA (Sus scrofa)


name: Phosphorylation of p-KIT on Y900 by Src kinases (Homo sapiens)


name: NUDT1 hydrolyses 8-oxo-dATP to 8-oxo-dAMP (Mus musculus)


name: an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine => all-trans-retinol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: PG is hydrolyzed to 1-acyl LPG by PLA2G4B (IM) (Homo sapiens)


name: (11R)-carlactonoate + S-adenosyl-L-methionine <=> (11R)-methyl carlactonoate + S-adenosyl-L-homocysteine


name: a 2-arylethylamine + acetyl-CoA => an N-acetyl-2-arylethylamine + CoA + H(+)


name: beta-amyrin + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 <=> oleanolate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: Formation of NR-MED1 Coactivator Complex (Sus scrofa)


name: glycochenodeoxycholate(out) + ADP + phosphate + H(+) => glycochenodeoxycholate(in) + ATP + H2O


name: p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Gallus gallus)


name: Phosphorylation of L1 by ERK (Dictyostelium discoideum)


name: RHOD translocates to the Golgi membrane (Gallus gallus)


name: Equilibrative transport (export) of adenosine and biogenic amines by solute carrier family 29 (nucleoside transporters), member 4 (Rattus norvegicus)


name: (5R)-5-phosphooxy-L-lysine + GDP + H(+) => (5R)-5-hydroxy-L-lysine + GTP


name: beta-muricholate + deoxycholoyl-CoA => beta-muricholoyl-CoA + deoxycholate


name: dihydromonacolin L carboxylate + reduced [NADPH--hemoprotein reductase] + O2 <=> monacolin L carboxylate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: loading of Serotonin in synaptic vesicles (Rattus norvegicus)


name: JAK1 binds IL4R in IL13-bound IL13R type II (Gallus gallus)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phosphate + choline + H(+)


name: Active FLT3 binds to CBL (Canis familiaris)


name: guanosine(2251) in 23S rRNA + S-adenosyl-L-methionine <=> 2'-O-methylguanosine(2251) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)


name: RDH12 reduces atRAL to atROL (Canis familiaris)


name: guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: negative regulation of lipid kinase activity


name: DHTKD1 dimer decarboxylates 2-OA (Xenopus tropicalis)


name: Formation of DRIP coactivator complex (Bos taurus)


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Saccharomyces cerevisiae)


name: SMAC binds XIAP:Caspase-7 (Mus musculus)


name: PDE3A inhibitors bind PDE3A (Canis familiaris)


name: (2E,6E)-farnesyl diphosphate <=> (S,S)-drim-8-en-11-yl diphosphate


name: kaempferol + UDP-beta-L-rhamnose = kaempferol 3-O-alpha-L-rhamnoside + UDP + H(+)


name: a 2'-deoxyadenosine in DNA + acetyl-CoA + AH2 + NH4(+) + O2 = a N(6)-methylcarbamoyl-2'-deoxyadenosine in DNA + A + CoA + 2 H2O + H(+)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Xenopus tropicalis)


name: docosanoyl-[(phenol)carboxyphthiodiolenone synthase] + 2 (S)-methylmalonyl-CoA + 3 malonyl-CoA + 5 NADPH + 10 H(+) = C34-carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone synthase] + 5 CO2 + 5 NADP(+) + 5 CoA + 2 H2O


name: a gentamycin + GTP => a gentamycin 2''-phosphate + GDP + H(+)


name: sn-glycerol 3-phosphate + NADP(+) <=> dihydroxyacetone phosphate + NADPH + H(+)


name: ergothioneine + pyruvate + A + NH4(+) => S-(hercyn-2-yl)-L-cysteine S-oxide + AH2 + H(+)


name: CLPXP binds mitochondrial matrix proteins (Drosophila melanogaster)


name: PKC-delta translocates to plasma membrane (Sus scrofa)


name: an alpha-D-mannosyl-(1<->6)-1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP + H(+) => a 1D-myo-inositol-1-phospho-N-[(R)-2-hydroxy-very-long-chain fatty acyl]-(R)-4-hydroxysphingoid base + GDP-alpha-D-mannose


name: Digestion of linear starch (amylose) by extracellular amylase (Bos taurus)


name: 4-(2,4-dichlorophenoxy)butanoate + L-glutamine + ATP => 4-(2,4-dichlorophenoxy)butanoyl-L-glutamine + AMP + diphosphate + H(+)


name: 5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Drosophila melanogaster)


name: (E)-hept-2-enal + NAD(+) + H2O => (E)-hept-2-enoate + NADH + 2 H(+)


name: L-tryptophan(out) + L-aspartate(in) => L-tryptophan(in) + L-aspartate(out)


name: Phosphorylation and release of IRF3/IRF7 (Homo sapiens)


name: 3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-methionine => 4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)


name: 6-amino-6-deoxyfutalosine + H2O = dehypoxanthine futalosine + adenine


name: (R)-acetoin + NAD(+) => diacetyl + NADH + H(+)


name: a fatty acid + NADH + 2 H(+) => a fatty aldehyde + NAD(+) + H2O


name: PLC-activating rhodopsin mediated signaling pathway


name: galactitol + NAD(+) => D-galactose + NADH + H(+)


name: NEIL1 cleaves FapyA from damaged DNA (Rattus norvegicus)


name: acetoacetyl-CoA + CoA <=> 2 acetyl-CoA (Dictyostelium discoideum)


name: STRAP stabilizes interaction of activated TGF-beta receptor complex with SMAD7 (Drosophila melanogaster)


name: ACE:Zn2+ hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7) (Drosophila melanogaster)


name: 4-amino-4-deoxychorismate => 4-aminobenzoate + pyruvate + H(+)


name: phosphonate + NAD(+) + H2O = phosphate + NADH + H(+)


name: 2-oxoglutarate(in) + H(+)(in) => 2-oxoglutarate(out) + H(+)(out)


name: CYP8B1 12-hydroxylates 4CHOL7aOLONE (Rattus norvegicus)


name: calcitriol + 2 oxidized [adrenodoxin] + H2O => alfacalcidol + 2 reduced [adrenodoxin] + O2 + 2 H(+)


name: PhosphoChREBP (Thr 653) is exported to cytosol (Drosophila melanogaster)


name: Phosphorylated KHDRBS1 translocates to the cytosol (Sus scrofa)


name: NUDT1 hydrolyzes N6-methyl-dATP to N6-methyl-dAMP (Danio rerio)


name: negative regulation of protein bioavailability


name: dodecanal + NADP(+) = (2E)-dodecenal + NADPH + H(+)


name: TP53 binds the CDKN1A promoter (Homo sapiens)


name: YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Canis familiaris)


name: F2R:ARRB1 binds MAPKs, SRC-1 (Homo sapiens)


name: Integrin alpha4beta1 binds JAM2:JAM3 (Xenopus tropicalis)


name: eIF2:GTP is hydrolyzed, eIFs are released  (Homo sapiens)


name: D-mannose 6-phosphate + H2O => D-mannose + phosphate


name: DNA polymerase epsilon binds at the origin (Homo sapiens)


name: histone kinase activity (H2A.x-S139 specific)


name: 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + phosphoenolpyruvate + H2O = N,N-diacetyllegionaminate + phosphate


name: (3R)-hydroxy-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + NADP(+) => 3-oxo-(15Z,18Z,21Z,24Z)-triacontatetraenoyl-CoA + NADPH + H(+)


name: adenylate cyclase inhibiting G protein-coupled glutamate receptor activity


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O = a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine


name: SGT1:HSP90 binds inactive NLRP3 (Xenopus tropicalis)


name: TBC1D20 stimulates GTPase activity of RAB1, resulting in hydrolysis of GTP (Homo sapiens)


name: NPAS4 binds RBFOX3 (NeuN) gene promoter (Homo sapiens)


name: 12R-HpETE is reduced to 12R-HETE by GPX1/2/4 (Canis familiaris)


name: Activation of ATP sensitive Potassium channels in neuroendocrine cells (Xenopus tropicalis)


name: 2xPPCS ligates PPanK with Cys (Bos taurus)


name: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + H(+)


name: Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Caenorhabditis elegans)


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Homo sapiens)


name: N-acetyl-S-(2-succino)-L-cysteine = N-acetyl-L-cysteine + fumarate


name: ACO1:4Fe-4S isomerises CIT to ISCIT (Homo sapiens)


name: glyoxylate + alanine => glycine + pyruvate [peroxisome] (Bos taurus)


name: MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG (Caenorhabditis elegans)


name: Mitofusins trans-interact linking mitochondria prior to fusion (Schizosaccharomyces pombe)


name: 5beta-cholestane-3alpha,7alpha,12alpha-triol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol + 2 oxidized [adrenodoxin] + H2O


name: D-maltose + acetyl-CoA => 1-O-acetylmaltose + CoA


name: Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Rattus norvegicus)


name: quercetin + S-adenosyl-L-methionine = rhamnetin + S-adenosyl-L-homocysteine + H(+)


name: Activation of TAK1 complex bound to activated TLR4 complex (Canis familiaris)


name: 6-phospho-D-gluconate + NADP+ => D-ribulose 5-phosphate + CO2 + NADPH + H+ (Canis familiaris)


name: FAAH hydrolyses AEA to AA and ETA (Bos taurus)


name: RNF41 binds neuregulin-activated ERBB3 (Bos taurus)


name: hypotaurine + NADPH + O2 + H(+) = taurine + NADP(+) + H2O


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + H2O => a 2,3-saturated aldehyde + sn-glycerol 3-phosphocholine


name: Autophosphorylation and activation of CAMK2 (Bos taurus)


name: bilirubin monoglucuronide glucuronyltransferase activity


name: PIAS4 SUMOylates PPARA with SUMO1 (Mus musculus)


name: DBI, ACBD7 bind MCFA-CoA and LCFA-CoA (Schizosaccharomyces pombe)


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H(+) => Fe(III)-di(C-5-deoxy-beta-D-glucosyl)-enterobactin + H2O


name: dTMP + H2O = 2-deoxy-D-ribose 5-phosphate + thymine


name: NOSTRIN mediated translocation of eNOS from plasma membrane (Danio rerio)


name: Reactive oxygen species oxidize DNAJA1 (Schizosaccharomyces pombe)


name: ERKs are inactivated by protein phosphatase 2A (Bos taurus)


name: Homodimerization  of DFF40 (Canis familiaris)


name: N-terminal peptidyl-amino acid deamination to pyruvic acid


name: 4-hydroxy-L-proline(out) + chloride(out) + 2 Na(+)(out) <=> 4-hydroxy-L-proline(in) + chloride(in) + 2 Na(+)(in)


name: dodecanoyl-CoA + (R)-carnitine = O-dodecanoyl-R-carnitine + CoA


name: octanal + NADP(+) <=> (2E)-octenal + NADPH + H(+)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Plasmodium falciparum)


name: N-(tetracosanoyl)-sphing-4-enine-1-phosphocholine + H2O = N-tetracosanoyl-sphing-4-enine + phosphocholine + H(+)


name: TPMT transfers CH3 from AdoMet to 6MP (Rattus norvegicus)


name: LIPA hydrolyses sterol esters to sterols and fatty acids (Canis familiaris)


name: di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-galactose <=> alpha-D-galactosyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA => a 1-acyl-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA


name: 1-(9Z-octadecenoyl)-3-(9Z,12Z-octadecadienoyl)-glycerol + CoA => 1-(9Z,12Z-octadecadienoyl)-glycerol + (9Z)-octadecenoyl-CoA


name: Phosphorylation of STAT1 by JAK kinases (Danio rerio)


name: L-methionyl-[protein] + S-adenosyl-L-methionine = S-methyl-L-methionyl-[protein] + S-adenosyl-L-homocysteine


name: quercetin + UDP-alpha-D-glucose <=> quercetin 3-O-beta-D-glucoside + UDP + H(+)


name: D-arabinose 5-phosphate => glycolaldehyde + D-glyceraldehyde 3-phosphate


name: NR1H2 or NR1H3, NRIP1 bind the SREBF1 gene (Homo sapiens)


name: NSF ATPase activity dissociates cis-SNARE at the ER (Mus musculus)


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Bos taurus)


name: beta-D-galacturonosyl di-trans,nona-cis-dodecaprenyl phosphate + UDP => di-trans,nona-cis-dodecaprenyl phosphate + UDP-alpha-D-galacturonate


name: D-glucuronate(out) + H(+)(out) = D-glucuronate(in) + H(+)(in)


name: Internalization of gap junction plaques (Gallus gallus)


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Mus musculus)


name: DOCK180:ELMO binds CRK (Canis familiaris)


name: Latent TGF-beta-1 is cleaved by FURIN (Drosophila melanogaster)


name: benzoate + reduced [NADPH--hemoprotein reductase] + O2 => 4-hydroxybenzoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Transfer of Ub from E2 to substrate and release of E2 (Dictyostelium discoideum)


name: a sphingoid base + octadecanoyl-CoA = an N-octadecanoyl-sphingoid base + CoA + H(+)


name: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + NADH + H(+)


name: dimethyl sulfoxide(in) <=> dimethyl sulfoxide(out)


name: PIAS1 SUMOylates DDX5 with SUMO2 (Bos taurus)


name: LXA4 is oxidised to 15k-LXA4 by HPGD (Danio rerio)


name: BIRC(cIAP1/2) ubiquitinates RIPK1 (Canis familiaris)


name: (2E)-but-2-enoyl-AMP + holo-[ACP] => (2E)-butenoyl-[ACP] + AMP + H(+)


name: [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O => [thyroglobulin]-L-tyrosine + iodide + H2O2 + H(+)


name: USP44 deubiquitinates CDC20 (Homo sapiens)


name: 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine + H(+) => 3,5-dimethoxyphenol + S-adenosyl-L-methionine


name: GLYCTK phosphorylates DGA to 3PDGA (Bos taurus)


name: 3,4-dihydroxybenzoate + bromide + NADPH + O2 + 2 H(+) = 3-bromo-4,5-dihydroxybenzoate + NADP(+) + 2 H2O


name: KIR3DL1 interacting with HLA Bw4 (Bos taurus)


name: 3-phosphoshikimate + ADP + H(+) => shikimate + ATP


name: N-(2-methylpropyl)hydroxylamine + FMN + H2O + 2 H(+) => 2-methylpropan-1-amine + FMNH2 + O2


name: a 3-acylpyruvate + H2O => a carboxylate + pyruvate + H(+)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Bos taurus)


name: CES3 hydrolyses CHEST to CHOL and LCFA(-) (Sus scrofa)


name: allocholate + lithocholoyl-CoA <=> allocholoyl-CoA + lithocholate


name: ROK phosphorylates SQH (Drosophila melanogaster)


name: positive regulation of proteolysis involved in protein catabolic process


name: ARL6:GTP and the BBSome bind ciliary cargo (Gallus gallus)


name: dodecanedioate + ATP + CoA = dodecanedioyl-CoA + AMP + diphosphate


name: ATXN3 family cleave Ub chains (Plasmodium falciparum)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Drosophila melanogaster)


name: 3-methylbutanal + NADP(+) + H2O => 3-methylbutanoate + NADPH + 2 H(+)


name: cob(I)yrinic acid a,c-diamide adenosyltransferase activity


name: glycine + 2 A <=> hydrogen cyanide + 2 AH2 + CO2


name: triphosphate + ADP + H(+) => diphosphate + ATP


name: TBC1D7 binds the TSC1-TSC2 complex (Drosophila melanogaster)


name: Reactive oxygen species oxidize DNAJA1 (Homo sapiens)


name: NUDT14 hydrolyses UDP-Glc to G1P and UMP (Drosophila melanogaster)


name: 2'-hydroxyformononetin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => formononetin + reduced [NADPH--hemoprotein reductase] + O2


name: SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) (Caenorhabditis elegans)


name: MAPKs phosphorylate PP2A (Rattus norvegicus)


name: Activated TLR5/TLR15 homodimer recruits MyD88 adaptor (Gallus gallus)