name: ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Sus scrofa)


name: EBP isomerizes ZYMSTNL to LTHSOL (Danio rerio)


name: SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Canis familiaris)


name: a 1-O-alkyl-sn-glycero-3-phosphate + ethanolamine + H(+) => a 1-O-alkyl-sn-glycero-3-phosphoethanolamine + H2O


name: regulation of ATP:citrate oxaloacetate-lyase [(pro-S)-CH2COO-rightacetyl-CoA] (ATP-dephosphorylating)


name: ESTG binds ESR2:chaperone complex (Rattus norvegicus)


name: mogroside IIE + UDP-alpha-D-glucose => mogroside IIIE + UDP + H(+)


name: sABO-A:Mn2+ transfers GalNAc to H antigen-sec to form A antigen-sec (Rattus norvegicus)


name: RAC1 GAPs stimulate RAC1 GTPase activity (Caenorhabditis elegans)


name: alpha-D-rhamnosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+) => GDP-alpha-D-rhamnose + N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate


name: Mevalonate is phosphorylated to mevalonate-5-phosphate (Caenorhabditis elegans)


name: C-ter TLR7 dimer binds HCQ (Gallus gallus)


name: N-acetyl-alpha-D-muramate 1-phosphate + ADP + H(+) => N-acetyl-D-muramate + ATP


name: FUNDC1 is phosphorylated by ULK1 at Ser17 (Saccharomyces cerevisiae)


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Rattus norvegicus)


name: L-amino acyl-L-threonyl-[protein] + ATP => (S,S)-2-(C-substituted-aminomethyl)-4-acyl-5-methyl-2-oxazoline-[protein] + ADP + phosphate + H(+)


name: STAP2 recruits STAT3 to PTK6 (Homo sapiens)


name: NANS converts ManNAc-6-P to Neu5Ac-9-P (Drosophila melanogaster)


name: L-threonyl-[protein] + GDP-beta-L-fucose <=> 3-O-(alpha-L-fucosyl)-L-threonyl-[protein] + GDP + H(+)


name: FOXO3 translocates from the mitochondrial matrix to the nucleus (Bos taurus)


name: TGFBR3_mem cleavage by MMPs (Mus musculus)


name: RPE dimers isomerise RU5P to XY5P (Dictyostelium discoideum)


name: 3-oxooctacosanyol-CoA + NADPH + H(+) <=> (3R)-hydroxyoctacosanoyl-CoA + NADP(+)


name: CYP4F22 20-hydroxylates TrXA3 (Xenopus tropicalis)


name: CCR2, CCR3 bind CCL13 (Rattus norvegicus)


name: GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Rattus norvegicus)


name: cGAS produces cyclic GMP-AMP (Homo sapiens)


name: Cleavage of S protein into S1:S2 (Homo sapiens)


name: hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Sus scrofa)


name: 2,3-di-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoyl-CoA <=> 1,2,3-tri-(9Z-octadecenoyl)-glycerol + CoA


name: Conformational change in gp120 of Env oligomer (Homo sapiens)


name: (3R)-hydroxydocosanoyl-CoA => (2E)-docosenoyl-CoA + H2O


name: mycophenolate + D-glucuronate + H(+) => mycophenolic acid O-acyl-beta-D-glucuronide + H2O


name: CDCA5 (Sororin) enables cohesion of sister centromeres (Homo sapiens)


name: UBC9 (UBE2I) SUMOylates RANGAP1 with SUMO, which targets RANGAP1 to RANBP2 (Schizosaccharomyces pombe)


name: GGCX gamma-carboxylates 3D-PROC(33-197) (pro-protein C light chain) (Rattus norvegicus)


name: maleate(in) + sulfate(out) = maleate(out) + sulfate(in)


name: Ubiquitination of IKBKG by TRAF6 (Mus musculus)


name: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-glucosamine = beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)


name: EPH receptors autophosphorylate (Drosophila melanogaster)


name: L-tryptophyl-5'-AMP + holo-[peptidyl-carrier protein] = L-tryptophyl-[peptidyl-carrier protein] + AMP


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Dictyostelium discoideum)


name: RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Bos taurus)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Mus musculus)


name: NME1,2 hexamers phosphorylate RBV-DP (Xenopus tropicalis)


name: [glutaredoxin]-dithiol + a hydroperoxide <=> [glutaredoxin]-disulfide + an alcohol + H2O


name: Exocytosis of secretory granule lumen proteins (Gallus gallus)


name: Dimerization of LIMK1 by Hsp90 (Gallus gallus)


name: 2 nitrate(out) + H(+)(out) <=> 2 nitrate(in) + H(+)(in)


name: G alpha (q) in G (q):RGS complex is inactivated (Danio rerio)


name: PLK1 phosphorylates BORA (Gallus gallus)


name: sugar transmembrane transporter activity


name: DLD dimer dehydrogenates dihydrolipoyl (Caenorhabditis elegans)


name: L-valine + NADP(+) + H2O => 3-methyl-2-oxobutanoate + NH4(+) + NADPH + H(+)


name: WLS:WNT complex is internalized for maturation into exosomes (Mus musculus)


name: COP9 and TOR1 deneddylate STON2 (Mus musculus)


name: RAN:GTP recruits nuclear envelope (NE) membranes (Rattus norvegicus)


name: uridine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methyluridine(32) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: SUMOylation of HDAC2 with SUMO1 (Sus scrofa)


name: Activated FGFR4:p-FRS binds GRB2:SOS1 (Drosophila melanogaster)


name: Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 (Canis familiaris)


name: acetyl-[citrate lyase ACP] + H2O => holo-[citrate lyase ACP] + acetate + H(+)


name: 6beta-hydroxycortisol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => cortisol + reduced [NADPH--hemoprotein reductase] + O2


name: 3-propylcatechol + NAD(+) + H2O => 2-propylphenol + NADH + O2 + H(+)


name: ethyl hexadecanoate + H2O = ethanol + hexadecanoate + H(+)


name: MCM4, MCM6 and MCM7 form a heterotrimer (Caenorhabditis elegans)


name: (11S,12R)-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2


name: acetyl-CoA + H2O => acetate + CoASH + H+ (Homo sapiens)


name: a medium-chain fatty acyl-CoA + 5 (S)-methylmalonyl-CoA + 5 malonyl-CoA + 22 NADPH + 32 H(+) => a mycoketide-CoA + 10 CO2 + 22 NADP(+) + 10 CoA + 11 H2O


name: (4S)-4-hydroxy-L-arginine => L-enduracididine + H2O


name: RHOG binds effectors at the plasma membrane (Drosophila melanogaster)


name: activation of protein K63-linked deubiquitination


name: ub-GLI is degraded by the proteasome (Xenopus tropicalis)


name: trimethylamine + NAD(+) + H2O <=> trimethylamine N-oxide + NADH + 2 H(+)


name: a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Canis familiaris)


name: USP19 deubiquitinates RNF123 (Rattus norvegicus)


name: prostaglandin F2alpha-CoA + H2O = prostaglandin F2alpha + CoA + H(+)


name: thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Bos taurus)


name: APC is K63-polyubiquitinated (Homo sapiens)


name: TP53 binds the ARID3A gene (Homo sapiens)


name: cytidine(34) in tRNA precursor + S-adenosyl-L-methionine <=> 5-methylcytidine(34) in tRNA precursor + S-adenosyl-L-homocysteine + H(+)


name: D-xylulose 5-phosphate + phosphate => D-xylulose 1,5-bisphosphate + H2O


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Saccharomyces cerevisiae)


name: 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: APOA1BP dimer epimerises R-NAD(P)HX to S-NAD(P)HX (Drosophila melanogaster)


name: Activated FGFR2 phosphorylates FRS2 (Drosophila melanogaster)


name: 5'-O-phosphonoadenylyl-(3'->5')-adenosine + H2O => 2 AMP + H(+)


name: 5-fluorocytidine + ATP => 5-fluorocytidine 5'-phosphate + ADP + H(+)


name: taurochenodeoxycholate(in) + glutathione(in) + ATP + H2O <=> taurochenodeoxycholate(out) + glutathione(out) + ADP + phosphate + H(+)


name: Caspase-mediated cleavage of Desmoglein 2 (Homo sapiens)


name: (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H(+) => (S)-2,3,4,5-tetrahydrodipicolinate + NADP(+) + H2O


name: 1,3-di-(9Z-octadecenoyl)-glycerol + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-(9Z-octadecenoyl)-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: PNPLA4 hydrolyzes TAG (Xenopus tropicalis)


name: Phosphorylated SPRY2 is ubiquitinated by CBL (Mus musculus)


name: VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Danio rerio)


name: Dissociation of Cdc20 from APC/C complex (Xenopus tropicalis)


name: Cipro:ALB dissociates (Xenopus tropicalis)


name: glycine betaine(in) + H(+)(in) <=> glycine betaine(out) + H(+)(out)


name: Release of GNB5:RGS dimers from CCT/TRiC (Homo sapiens)


name: MAGT1 transports Mg2+ from extracellular region to cytosol (Danio rerio)


name: Isomerization of GlcNAc6P to GlcNAc1P (Caenorhabditis elegans)


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Xenopus tropicalis)


name: gamma-L-glutamyl-hercynylcysteine S-oxide + H2O => S-(hercyn-2-yl)-L-cysteine S-oxide + L-glutamate


name: 2-oxosuccinamate + H2O2 + NH4(+) => D-asparagine + O2 + H2O


name: CDK1 phosphorylates condensin II subunit NCAPD3 (Rattus norvegicus)


name: PI(3,5)P2 is dephosphorylated to PI5P by MTM proteins at the late endosome membrane (Saccharomyces cerevisiae)


name: TCR complex interacts with peptide antigen-presenting MHC Class I (Sus scrofa)


name: PHF8 demethylates histone H4K20me1 (Plasmodium falciparum)


name: aromatic amino acid family biosynthetic process, shikimate pathway


name: CD28 homodimer binds B7-2 monomer (Bos taurus)


name: (2S)-liquiritigenin + reduced [NADPH--hemoprotein reductase] + O2 <=> (2R,3S)-2,4',7-trihydroxyisoflavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + 2 S-adenosyl-L-homocysteine => a 5'-end 5'-phospho-ribonucleoside-RNA + 2 S-adenosyl-L-methionine


name: trimethyluric acid monooxygenase activity


name: RAB:GTP recruits GBF1 to the Golgi membrane (Bos taurus)


name: GSK3B phosphorylates p-S73 MITF-M at residue S69 (Sus scrofa)


name: Complement factor I binds C4BP (Homo sapiens)


name: Binding of AP1 transcriptional activator complexes to CCND1 promoter (Homo sapiens)


name: gamma-L-glutamyl-butirosin B <=> butirosin B + 5-oxo-L-proline


name: dihydroxyacetone + ATP => dihydroxyacetone phosphate + ADP + H(+)


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Canis familiaris)


name: hydroxymalonate + NAD(+) => oxomalonate + NADH + H(+)


name: nonanoyl-CoA + FAD + H(+) = (2E)-nonenoyl-CoA + FADH2


name: MLCL is acylated to CL by HADH (IM) (Caenorhabditis elegans)


name: a 2-acylglycerol + H2O = glycerol + a fatty acid + H(+)


name: an R-cob(III)alamin(in) => an R-cob(III)alamin(out)


name: a 1-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)


name: a phenyl acetate + H2O = a phenol + acetate + H(+)


name: CHRM1,3,5 bind CHRM1,3,5 antagonists (Gallus gallus)


name: an N-(fatty acyl)-L-glutamine + H2O = L-glutamine + a fatty acid


name: an N-carbamoyl-L-alpha-amino acid + H2O + 2 H(+) <=> an L-alpha-amino acid + NH4(+) + CO2


name: GPX4-2 reduces 18(S)-HpEPE to 18(S)-HEPE (Rattus norvegicus)


name: Hydrolysis of PIP2 by PLCG (Homo sapiens)


name: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O => 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate


name: Association of procollagen type XVIII (Danio rerio)


name: MITF-M dimer binds SIRT1 promoter (Homo sapiens)


name: SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Bos taurus)


name: Excision of the abasic sugar phosphate (5'dRP) residue at the single strand break (Sus scrofa)


name: NNT dimer transfers proton from NADPH to NAD+ (Danio rerio)


name: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + 9-hydroxy-octadecanoate => 1,3-di-(9Z,12Z)-octadecadienoylglycerol + 9-(9Z,12Z-octadecadienoyloxy)-octadecanoate


name: activation of protein amino acid phosphorylation


name: Trafficking of GluR2-containing AMPA receptors to synapse (Sus scrofa)


name: RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Mus musculus)


name: NRF1:p-PPARGC1A, NRF2 bind the TFB2M promoter (Homo sapiens)


name: 1-octadecanoyl-sn-glycero-3-phosphocholine + acetyl-CoA <=> 1-octadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + CoA


name: 25(R) THCA-CoA is translocated from the cytosol to the peroxisome (Homo sapiens)


name: an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+) => a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O


name: [phosphate](n+1) + n H2O = (n+1) phosphate + n H(+)


name: 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + phosphate


name: Binding of the MCC complex to the APC/C complex (Drosophila melanogaster)


name: Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Mus musculus)


name: hexadecanamide + H2O = hexadecanoate + NH4(+)


name: 21-hydroxyprogesterone + 2 reduced [adrenodoxin] + O2 + 2 H(+) <=> 18-hydroxy-11-deoxycorticosterone + 2 oxidized [adrenodoxin] + H2O


name: Phosphorylation of Ribosomal protein S6 by activated S6K1 (Homo sapiens)


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Drosophila melanogaster)


name: a 12-oxojasmonyl-L-alpha-amino acid + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => a 12-hydroxyjasmonyl-L-alpha-amino acid + reduced [NADPH--hemoprotein reductase] + O2


name: lipopolysaccharide glucosyltransferase I activity


name: SORD tetramer oxidizes xylitol to D-xylulose (Homo sapiens)


name: p-AKT2 phosphorylates Myosin 5A (Homo sapiens)


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)


name: HEXA cleaves the terminal GalNAc from keratan sulfate (Rattus norvegicus)


name: ROS,RNS oxidize ACO2:4Fe-4S (Saccharomyces cerevisiae)


name: castasterone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => 6alpha-hydroxycastasterone + reduced [NADPH--hemoprotein reductase] + O2


name: 4-methyl-5-oxo-octanedioyl-CoA + acetyl-CoA => 6-methyl-3,7-dioxodecanedioyl-CoA + CoA


name: Nectin-1:Nectin-4 trans heterodimer formation (Gallus gallus)


name: KIR3DL1 interacting with HLA Bw4 (Homo sapiens)


name: a ganglioside GD2 (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD2(d18:1(4E)) + CoA


name: Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Gallus gallus)


name: monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity


name: KLK5 cleaves and activates KLK8 (Bos taurus)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (XIIa catalyst) (Homo sapiens)


name: LTCC multimer transports Ca2+ from extracellular region to cytosol (Mus musculus)


name: UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Caenorhabditis elegans)


name: TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Bos taurus)


name: Phosphorylation of MEF2 proteins by p38 (Gallus gallus)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+) => 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP


name: bHEXA,bHEXS hydrolyze GM2A:SM2 (Homo sapiens)


name: UGT1A4 transfers GlcA from UDP-GlcA to BIL to form BMG (Bos taurus)


name: SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Danio rerio)


name: NTHL1 D239Y does not cleave thymine glycol (Tg) (Homo sapiens)


name: PIAS1,3,4 SUMOylate MTA1 with SUMO2,3 (Gallus gallus)


name: ambiguine A + diphosphate => hapalindole G + dimethylallyl diphosphate


name: XDH dehydrogenates hypoxanthine to form xanthine (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1-acyl-sn-glycero-3-phosphocholine = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: XPO1 binds p-S69,73 MITF-M (Canis familiaris)


name: Association of INK4 family proteins with CDK4/6 (Gallus gallus)


name: Interaction of APS and p-KIT (Rattus norvegicus)


name: ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)


name: SFKs phosphorylates RAF1 on Y340,Y341 (Rattus norvegicus)


name: TSTA3 dimer reduces GDP-KDGal to GDP-Fuc (Caenorhabditis elegans)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Bos taurus)


name: Relaxin receptor 2 binds relaxin 2 and INSL3 (Mus musculus)


name: activation of p-phenylphenol glucuronyltransferase activity


name: all-trans-hexaprenol + ATP = all-trans-hexaprenyl phosphate + ADP + H(+)


name: lipid A disaccharide (E. coli) + ATP <=> lipid IVA (E. coli) + ADP + H(+)


name: a globoside Gb3Cer (d18:1(4E)) + UDP-alpha-D-galactose => a globoside GalGb3Cer (d18:1(4E)) + UDP + H(+)


name: ANOs transport cytosolic Cl- to extracellular region (Schizosaccharomyces pombe)


name: D-glucurono-3,6-lactone + H2O = D-glucuronate + H(+)


name: beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-D-Glc + an N-acyl-sphingoid base => a ganglioside GM1 + H2O


name: (2Z,6Z)-farnesyl diphosphate <=> alpha-humulene + diphosphate


name: 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 => 2 L-citrulline + 2 nitric oxide + NAD(+) + 2 H2O + H(+)


name: Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Sus scrofa)


name: (11E)-octadecenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> (5Z,11E)-octadecadienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: ERCC8:DDB1:CUL4:RBX1 ubiquitinates ERCC6 and RNA Pol II (Gallus gallus)


name: Necl-1:Nectin 3 trans heterodimer interaction (Sus scrofa)


name: L-threo-7,8-dihydrobiopterin + NADP(+) <=> sepiapterin + NADPH + H(+)


name: 22-methyltricosan-1-ol + (9Z)-octadecenoyl-CoA <=> 1-O-22-methyltricosyl (9Z)-octadecenoate + CoA


name: L-lysyl(36)-[histone H3] + S-adenosyl-L-methionine <=> N(6)-methyl-L-lysyl(36)-[histone H3] + S-adenosyl-L-homocysteine + H(+)


name: 4-hydroxybenzoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => benzoate + reduced [NADPH--hemoprotein reductase] + O2


name: 2-methylbutan-1-ol + butanoyl-CoA = 2-methylbutyl butanoate + CoA


name: L-arginyl-L-alpha-amino acid(in) => L-arginyl-L-alpha-amino acid(out)


name: CREBBP binds FOXO1 (Caenorhabditis elegans)


name: 2-dehydro-3-deoxy-L-fuconate + H2O => L-fuconate


name: LTC4 is exported from the cytosol by ABCC1 (Saccharomyces cerevisiae)


name: adenosine(9) in tRNA + S-adenosyl-L-methionine <=> N(1)-methyladenosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)


name: testosterone dehydrogenase (NAD+) activity


name: inhibition of o-orsellinic acid biosynthetic process


name: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2-methylpropanoyl-CoA => N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CoA


name: MAPK12 phosphorylates PTPN3 (Mus musculus)


name: HSD11B2,HSD11B1 dimer oxidise CORT to COR (Homo sapiens)


name: 1,8-cineole + reduced [NADPH--hemoprotein reductase] + O2 <=> 2-exo-hydroxy-1,8-cineole + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: N-acetyl-D-muramate 6-phosphate + H2O <=> N-acetyl-D-muramate + phosphate


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1,2-dihexadecanoyl-sn-glycerol + phosphocholine + H(+)


name: CTLH E3 ligase ubiquitinates PKM-1 (Xenopus tropicalis)


name: epidermal growth factor receptor binding


name: N,N'-diacetylchitobiono-1,5-lactone + H2O <=> N,N'-diacetylchitobionate + H(+)


name: HSD17B1 hydrogenates E1 to EST17b (Schizosaccharomyces pombe)


name: 1-octadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + H2O = 1-octadecanoyl-sn-glycero-3-phosphocholine + octanoate + H(+)


name: daidzein + UDP-alpha-D-glucose = daidzein 7-O-beta-D-glucoside + UDP


name: TPI1 isomerizes GA3P to DHAP (Bos taurus)


name: L-cystine(out) + H(+)(out) <=> L-cystine(in) + H(+)(in)


name: naphthalene-1,2-diol + CO2 + NADP(+) + H2O => 1-hydroxy-2-naphthoate + NADPH + O2 + 2 H(+)


name: ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine


name: tauro-beta-muricholate(out) + 2 Na(+)(out) => tauro-beta-muricholate(in) + 2 Na(+)(in)


name: Binding of ADAR1 homodimer to dsRNA duplex (Homo sapiens)


name: a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl-(1<->6)-D-myo-inositol] + GDP-alpha-D-mannose => a 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+)


name: STAT3 binds activated MET receptor (Bos taurus)


name: pre-VLDL translocates from RER membrane to SER lumen (Canis familiaris)


name: Integrin alphaIIb beta3 activation (Caenorhabditis elegans)


name: a ganglioside GD1a + CMP + H(+) => a ganglioside GM1 + CMP-N-acetyl-beta-neuraminate


name: (3R)-hydroxyhexadecanoyl-CoA + NAD(+) <=> 3-oxohexadecanoyl-CoA + NADH + H(+)


name: NUDT16 hydrolyses IDP to IMP (Danio rerio)


name: Ubiquitin-dependent degradation of the SMAD complex terminates TGF-beta signaling (Sus scrofa)


name: Interaction of Bcl10 to CARMA1 (Gallus gallus)


name: ABCC1,ABCG2 transport C18-S1P to extracellular region (Dictyostelium discoideum)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Sus scrofa)


name: Cleavage of Procaspase‑9 to caspase‑9 (Bos taurus)


name: (R)-mevalonate + ATP <=> (R)-3-phosphomevalonate + ADP + H(+)


name: phosphonoacetaldehyde + NH4(+) => (1R)-(2-amino-1-hydroxyethyl)phosphonate


name: AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Bos taurus)


name: 3-hydroxypristanoyl-CoA + NAD+ => 3-ketoxypristanoyl-CoA + NADH + H+ (Drosophila melanogaster)


name: L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-methionine => N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: HSP90:FKBP4:PTGES3 binds HSF1 trimer (Bos taurus)


name: Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz (Sus scrofa)


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Xenopus tropicalis)


name: ITGA4:ITGB1 binds natalizumab (Xenopus tropicalis)


name: Dehalogenation of carbon tetrachloride to form a free radical (Bos taurus)


name: S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Sus scrofa)


name: SALL4 recruits NuRD to PTEN gene (Mus musculus)


name: Formation of cap binding complex (CBC) (Caenorhabditis elegans)


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)


name: 1-deoxy-D-xylulose + ATP <=> 1-deoxy-D-xylulose 5-phosphate + ADP + H(+)


name: p-5Y-RET complexes bind GRB2 (Gallus gallus)


name: COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Dictyostelium discoideum)


name: inhibition of N-acylneuraminate glycohydrolase activity


name: MPI isomerises Fru6P to Man6P (Mus musculus)


name: TNF-alpha inhibitors bind to TNF(1-233) trimer (Xenopus tropicalis)


name: POMP binds the 20S core particle outer ring (Sus scrofa)


name: (1R,3R)-chrysanthemal + NADP(+) + H2O = (1R,3R)-chrysanthemate + NADPH + 2 H(+)


name: prenol + diphosphate => dimethylallyl diphosphate + H2O


name: a beta-D-glucuronoside + H2O => D-glucuronate + an alcohol


name: trans-2,3-dehydropristanoyl-CoA + H2O => 3-hydroxypristanoyl-CoA (Rattus norvegicus)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Sus scrofa)


name: Interaction of Csk with PAG (Canis familiaris)


name: mycophenolate + UDP-alpha-D-glucuronate = mycophenolic acid O-acyl-beta-D-glucuronide + UDP


name: a 1-acyl-sn-glycerol + ATP = a 1-acyl-sn-glycero-3-phosphate + ADP + H(+)


name: HTN5, (HTN1, HTN3) binds fungal SSA1/SSA2 (Homo sapiens)


name: NEDD8 binds CUL1 (in SKP1:CUL1:FXBL5) (Mus musculus)


name: ING2 recruits EP300 to TP53 (Drosophila melanogaster)


name: Inhibition of integrin activation by sequestering PIP5KIgamma (Sus scrofa)


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Sus scrofa)


name: myo-inosose-5 + NADH + H(+) => myo-inositol + NAD(+)


name: negative regulation of nitrogen compound metabolic process


name: a chlorophyll + H2O <=> a chlorophyllide + phytol + H(+)


name: PI3P is dephosphorylated to PI by MTM1:MTMR12 (Homo sapiens)


name: Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Gallus gallus)


name: holo-[mycolipanoate synthase] + a long-chain fatty acyl-CoA + 3 (S)-methylmalonyl-CoA + 6 NADPH + 9 H(+) <=> long-chain mycolipanoyl-[mycolipanoate synthase] + 3 CO2 + 6 NADP(+) + 4 CoA + 3 H2O


name: p-5Y-RET complexes bind GRB2 (Rattus norvegicus)


name: S-(4-hydroxy-3-methylbutan-2-yl)-L-cysteine = 2-methyl-3-sulfanylbutan-1-ol + 2-aminoprop-2-enoate


name: CARKD dehydrates S-NAD(P)HX to NADPH (Dictyostelium discoideum)


name: PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Dictyostelium discoideum)


name: SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Bos taurus)


name: RAS GEFs promote RAS nucleotide exchange (Sus scrofa)


name: a 1-acylglycerone 3-phosphate + hexadecanoate => 1-hexadecanoylglycerone 3-phosphate + a long-chain fatty acid


name: Formation of the SCF-FBXL7 complex (Gallus gallus)


name: 1-hexadecanoyl-2-butanoyl-sn-glycero-3-phosphocholine + H2O = butanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: type I site-specific deoxyribonuclease activity


name: cholestanol + reduced [NADPH--hemoprotein reductase] + O2 => (24S)-hydroxycholestanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 2-thiocytidine + ATP = 2-thiocytidine 5'-phosphate + ADP + H(+)


name: MVD decarboxylates MVA5PP to IPPP (Homo sapiens)


name: L-ribulose 5-phosphate + H2O = L-ribulose + phosphate


name: MITF-M dimer, SOX10, pS133 CREB1 and CTNNB1:LEF1 bind the DCT promoter (Homo sapiens)


name: 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoserine + H2O => 1-octadecanoyl-sn-glycero-3-phosphoserine + (9Z,12Z)-octadecadienoate + H(+)


name: N-terminal N(alpha)-acetyl-L-cysteinyl-L-aspartyl-[protein] + H2O => N-terminal L-aspartyl-[protein] + N-acetyl-L-cysteine


name: Formation of tri-heterotetramers of GluN1 (GRIN1), GluN2B (GRIN2B) and GluN3B (GRIN3B) (Homo sapiens)


name: Caspase-mediated cleavage of GAS2 (Canis familiaris)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Gallus gallus)


name: L-alanylglycine(out) + ATP + H2O = L-alanylglycine(in) + ADP + phosphate + H(+)


name: Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme (Bos taurus)


name: positive regulation of peptidyl-tyrosine autophosphorylation


name: HDAC10 deacetylates histone (Saccharomyces cerevisiae)


name: GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Gallus gallus)


name: Sulfido conjugates translocate from cytosol to extracellular region (Homo sapiens)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Caenorhabditis elegans)


name: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside 3-phosphate + H2O <=> 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + phosphate


name: activation of cutin biosynthetic process


name: activation of diacylglycerol:ATP kinase activity


name: quinolin-2-ol + NADH + O2 + H(+) => quinoline-2,8-diol + NAD(+) + H2O


name: [(2->1)-beta-D-fructosyl](n) + sucrose = [(2->1)-beta-D-fructosyl](n+1) + D-glucose


name: N-terminal L-methionyl-L-seryl-[protein] + acetyl-CoA <=> N-terminal N(alpha)-acetyl-L-methionyl-L-seryl-[protein] + CoA + H(+)


name: 4-hydroxy-L-threonine = glycolaldehyde + glycine


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Caenorhabditis elegans)


name: (2R)-2-phosphoglycerate <=> phosphoenolpyruvate + H2O


name: Formation of MSH1:PMS2 Complex (Saccharomyces cerevisiae)


name: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A44 + succinate + CO2


name: 11-demethylbrucine + S-adenosyl-L-methionine => brucine + S-adenosyl-L-homocysteine + H(+)


name: galactarate + (E)-feruloyl-CoA => 2-O-[(E)-feruloyl]-D-galactarate + CoA


name: Luteinizing hormone receptor can bind LH (Danio rerio)


name: WICH phosphorylates H2AFX on Y142 (Rattus norvegicus)


name: 1-hexadecanoyl-2-pentanoyl-sn-glycero-3-phosphocholine + H2O <=> pentanoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: triuret + H2O = 1-carboxybiuret + NH4(+)


name: 4alpha-carboxyzymosterol + 6 Fe(III)-[cytochrome b5] + 4 H2O => 4alpha-methylzymosterol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+)


name: peniprequinolone + A = yaequinolone E + AH2


name: (4aR,7S)-2-(adenosyl(5')diphospho(5)ribosyl)-7-amino-4-carbamoyl-4a,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-7-carboxylate + S-methyl-5'-thioadenosine + 2 H(+) => S-adenosyl-L-methionine + NAD(+)


name: adenylyl-molybdopterin + tungstate = W-molybdopterin cofactor + AMP + H(+)


name: 3-oxooctadecanoyl-[ACP] + holo-[ACP] + CO2 => hexadecanoyl-[ACP] + malonyl-[ACP] + H(+)


name: ALDHs oxidise atRAL to atRA (Homo sapiens)


name: Formation of BRCA1-A complex at DNA DSBs (Rattus norvegicus)


name: glycolate(in) + H(+)(in) <=> glycolate(out) + H(+)(out)


name: 7-deoxycylindrospermopsin + 2-oxoglutarate + O2 => cylindrospermopsin + succinate + CO2


name: N-(15Z-tetracosenoyl)sphing-4-enine-1-phosphocholine + H2O = N-(15Z-tetracosenoyl)-sphing-4-enine + phosphocholine + H(+)


name: a 1,N(2)-etheno-2'-deoxyguanosine in double-stranded DNA + 2-oxoglutarate + O2 + H2O <=> a 2'-deoxyguanosine in double-stranded DNA + glyoxal + succinate + CO2


name: p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2 (Xenopus tropicalis)


name: sphing-4-enine 1-phosphate(in) => sphing-4-enine 1-phosphate(out)


name: D-aspartate(out) + K(+)(in) + 3 Na(+)(out) + H(+)(out) = D-aspartate(in) + K(+)(out) + 3 Na(+)(in) + H(+)(in)


name: 4-imidazolone-5-propionate + H2O => N-formiminoglutamate (Caenorhabditis elegans)


name: gap junction channel activity involved in atrial cardiomyocyte-AV node cell electrical coupling


name: ULK complex translocates to the ER (Xenopus tropicalis)


name: UDP-N-acetyl-6-(alpha-D-galactose-1-phospho)-alpha-D-glucosamine + UMP + H(+) => UDP-N-acetyl-alpha-D-glucosamine + UDP-alpha-D-galactose


name: L-tryptophyl-[peptidyl-carrier protein] + AMP + diphosphate => holo-[peptidyl-carrier protein] + L-tryptophan + ATP


name: CYB5A:heme reduces Asc.- to AscH- (Saccharomyces cerevisiae)


name: 2-hydroxyethylphosphonate + NAD(+) => phosphonoacetaldehyde + NADH + H(+)


name: 9-cis-retinal + NAD(+) + H2O => 9-cis-retinoate + NADH + 2 H(+)


name: POMT1:POMT2 transfers Man from Dol-P-Man to DAG1(30-653) (Bos taurus)


name: DLST transfers succinyl to CoA (Schizosaccharomyces pombe)


name: EGFR binds EPS15, EPN1, EPS15L1 (Caenorhabditis elegans)


name: Activated FGFR4 phosphorylates SHC1 (Canis familiaris)


name: ULK1 phosphorylates Beclin-1 (Dictyostelium discoideum)


name: Exocytosis of platelet dense granule content (Drosophila melanogaster)


name: (S)-1-hydroxy-N-methylcanadine + reduced [NADPH--hemoprotein reductase] + O2 = (13S,14R)-1,13-dihydroxy-N-methylcanadine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: butanoyl-CoA + hydrogencarbonate + ATP <=> (2R)-ethylmalonyl-CoA + ADP + phosphate + H(+)


name: (S,S)-tartrate(out) + sulfate(in) => (S,S)-tartrate(in) + sulfate(out)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Rattus norvegicus)


name: p-S13-FUNDC1 is dephosphorylated by PGAM5 (Danio rerio)


name: 1-O-tetradecyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-tetradecyl-sn-glycero-3-phosphocholine + acetate + H(+)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 => (8R)-hydroperoxy-(9E,11Z,14Z)-eicosatrienoate


name: Oligomerization of CARMA1 (Gallus gallus)


name: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-alpha-D-galactose => beta-D-Gal-(1->4)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + UDP + H(+)


name: PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)


name: 7(1)-hydroxychlorophyllide a + NADPH + O2 + H(+) = chlorophyllide b + NADP(+) + 2 H2O


name: 2-oxobutanoate + NAD(+) + CoA <=> propanoyl-CoA + CO2 + NADH


name: (2R,3S)-homoisocitrate + NAD(+) = 2-oxoadipate + CO2 + NADH


name: CDH11 associates with catenins (Mus musculus)


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Canis familiaris)


name: QPRT transfers PRIB to QUIN to form NAMN (Bos taurus)


name: N-acetyl-alpha-D-glucosaminyl-1-diphospho-trans,octa-cis-decaprenol + dTDP-beta-L-rhamnose = alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + dTDP + H(+)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the nucleus (Caenorhabditis elegans)


name: HSPG2 (perlecan) degradation by MMP14, MMP15 (Drosophila melanogaster)


name: L-asparagine + O2 + H2O => 2-oxosuccinamate + H2O2 + NH4(+)


name: TRAF6 is K63 poly-ubiquitinated (Dictyostelium discoideum)


name: (1S,5S)-carveol + NAD(+) = (S)-carvone + NADH + H(+)


name: HS3STs sulfate GlcN at C3 in heparan sulfate (Danio rerio)


name: activation of asperfuranone biosynthetic process


name: C-terminal L-alpha-aminoacyl-L-glutamyl-[tubulin] + H2O <=> C-terminal L-alpha-aminoacyl-[tubulin] + L-glutamate


name: MHC class I protein binding, via lateral surface


name: SQSTM1 oligomerizes (Drosophila melanogaster)


name: (R)-5-phosphomevalonate = (2E)-3-methyl-5-phosphooxypent-2-enoate + H2O


name: glutarate(in) + 2-oxoglutarate(out) <=> glutarate(out) + 2-oxoglutarate(in)


name: MKL1 translocates from cytosol to the nucleus (Canis familiaris)


name: 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H(+)


name: 9-hydroxy-octadecanoate + octadecanoate + H(+) => 9-octadecanoyloxy-octadecanoate + H2O


name: GLYAT-like proteins transfer glycine to ST-CoA to form SUA (Rattus norvegicus)


name: spermidine + O2 + H2O = 4-aminobutanal + propane-1,3-diamine + H2O2


name: Connection of adjacent cells through calcium-dependent trans-dimerization of cadherin (Bos taurus)


name: Dissociation of the SPINK5:KLK5 complex at low pH (Homo sapiens)


name: a 2-hydroxy carboxylate + O2 => a 2-oxocarboxylate + H2O2


name: [(1->6)-alpha-D-glucosyl](n) + sucrose = (1->3)-alpha-D-glucosyl-[(1->6)-alpha-D-glucosyl](n) + D-fructose


name: decarboxy 3-dehydropresphingofungin + CO2 => 3-oxopresphingofungin + 2 H(+)


name: pravastatin(in) + ATP + H2O = pravastatin(out) + ADP + phosphate + H(+)


name: (19E)-geissoschizine + reduced [NADPH--hemoprotein reductase] + O2 => 3,17-didehydrostemmadenine + oxidized [NADPH--hemoprotein reductase] + 2 H2O


name: protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine


name: 3-maleylpyruvate + H2O => maleate + pyruvate + H(+)


name: 2-demethylmenaquinol-8 + dimethyl sulfoxide => 2-demethylmenaquinone-8 + dimethyl sulfide + H2O


name: Receptor CCR11 binds CCL19, CCL21 & CCL25 (Homo sapiens)


name: all-trans-retinol--[retinol-binding protein] + a 1,2-diacyl-sn-glycero-3-phosphocholine => apo--[retinol-binding protein] + an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine


name: all-trans-retinol + 2 reduced [adrenodoxin] + O2 + 2 H(+) <=> all-trans-4-hydroxyretinol + 2 oxidized [adrenodoxin] + H2O


name: Photons induce isomerisation of 11c-retinyl to at-retinyl (Sus scrofa)


name: CHEK2 is recruited to DNA DSBs (Rattus norvegicus)


name: 7-acetyl-epi-neemfruitin B + AH2 + H2O = (1S,3bR,4R,5aR,9aR,9bR,11aS)-1-[(4R)-5-[(2S)-3,3-dimethyloxiran-2-yl]-1,4-dihydroxybutan-2-yl]-3b,6,6,9a,11a-pentamethyl-7-oxo-1H,2H,3bH,4H,5H,5aH,6H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-4-yl acetate + acetate + A + H(+)


name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Schizosaccharomyces pombe)


name: RISC binds inexactly matching target RNAs (Bos taurus)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Caenorhabditis elegans)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Canis familiaris)


name: L-alanyl-L-histidine + H2O <=> L-histidine + L-alanine


name: (3R)-3-hydroxy-2,3-dihydrotabersonine + A => (3R)-1,2-didehydro-3-hydroxy-2,3-dihydrotabersonine + AH2


name: Prostaglandin E synthase isomerizes PGH2 to PGE2 (Homo sapiens)


name: a 2,3-saturated fatty acid + H2O2 => a 3-hydroxy fatty acid + H2O


name: Mitogen-Activated Protein Kinase Kinase Inhibitors [MoA]


name: HAO1 tetramer oxidizes glycolate to glyoxylate (Mus musculus)


name: beta-L-arabinofuranosyl-(1->2)-beta-L-arabinofuranose + H2O => 2 beta-L-arabinofuranose


name: an L-alpha-amino acid + cholate => an N-choloyl-L-alpha-amino acid + H2O


name: FLT3 mutants:GRB2 bind GAB2 (Homo sapiens)


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Mus musculus)


name: Spontaneous hydrolysis of C3 thioester (Xenopus tropicalis)


name: UDP-alpha-D-galactose(out) + CMP(in) => UDP-alpha-D-galactose(in) + CMP(out)


name: Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines (Canis familiaris)


name: factor IXa associates with cell membrane (Sus scrofa)


name: methyl 8-{[alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate + GDP-beta-L-fucose => methyl 8-{[alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc]oxy}nonanoate + GDP + H(+)


name: Uncoupled eNOS favours the formation of superoxide (Drosophila melanogaster)


name: CCS transfers Cu to SOD1 and oxidizes cysteine residues in SOD1 (Drosophila melanogaster)


name: octadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (9Z)-octadecenoyl-[ACP] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: all-trans-4,4'-diapophytofluene + FAD + H(+) => all-trans-4,4'-diapo-zeta-carotene + FADH2


name: N(6)-D-ribulosyl-L-lysyl-[protein] + phosphate => N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] + H2O


name: GM-CSF receptor alpha subunit binds GM-CSF (Sus scrofa)


name: NR1H4 binds DCA, CDCA, LCHA (Drosophila melanogaster)


name: PRKN ubiquitinates MOM substrates (Danio rerio)


name: 1-acyl LPI is acylated to PI by MBOAT7 (Drosophila melanogaster)


name: POMP binds the 20S core particle outer ring (Drosophila melanogaster)


name: Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Saccharomyces cerevisiae)


name: 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O <=> 1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + N-hexadecanoylethanolamine + H(+)


name: a beta-D-galactoside + CMP-N-acetyl-beta-neuraminate <=> an N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H(+)


name: beta-nicotinamide D-riboside + H2O = D-ribose + nicotinamide + H(+)


name: SUMOylation of NFKBIA with SUMO1 (Gallus gallus)


name: (5R,7aS)-5-hydroxy-7a-methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + NAD(+) => (7aS)-7a-methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-carboxyl-CoA + NADH + H(+)


name: CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Xenopus tropicalis)


name: butan-2-one + hydrogen cyanide => 2-hydroxy-2-methylbutanenitrile


name: S100A8:S100A9 binds TLR4:LY96 (Mus musculus)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)


name: N-acetyl-D-glutamate + CoA + H(+) => D-glutamate + acetyl-CoA


name: uroporphyrinogen I + 4 H(+) <=> coproporphyrinogen I + 4 CO2


name: a primary amine + S-adenosyl-L-methionine => a methylated primary amine + S-adenosyl-L-homocysteine + H(+)


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Homo sapiens)


name: TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III (Rattus norvegicus)


name: N-terminal peptidyl-proline dimethylation involved in translation


name: (5Z,8Z,11Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 19-hydroxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: demethoxycurcumin synthase activity from feruloylacetyl-CoA


name: activation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning


name: generation of precursor metabolites and energy


name: VEGF-A,C,D bind to VEGFR2 leading to receptor dimerization (Bos taurus)


name: an alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+) => a beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose


name: glycine + O2 => glyoxylate + H2O2 + NH4+ (Homo sapiens)


name: (R,R)-chrysanthemol + NAD(+) = (1R,3R)-chrysanthemal + NADH + H(+)


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-RNA + a ribonucleoside 5'-triphosphate => a 5'-end NTP-ribonucleotide-RNA + AMP + H(+)


name: NaDC1 co-transports dicarboxylic acids and a sodium ion (Caenorhabditis elegans)


name: phytyl diphosphate + chlorophyllide a + H(+) <=> chlorophyll a + diphosphate


name: D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)


name: IRF1 binds the promoters of Interferon alpha and beta (Homo sapiens)


name: 3,3',5-triiodo-L-thyronine(out) + L-tryptophan(in) = 3,3',5-triiodo-L-thyronine(in) + L-tryptophan(out)


name: genistein + reduced [NADPH--hemoprotein reductase] + O2 <=> 2'-hydroxygenistein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: NEDD4 binds ERBB4jmAcyt1s80 dimer (Canis familiaris)


name: N-(dodecanoyl)-sphinganine + H2O => dodecanoate + sphinganine


name: 2-methoxy-6-(all-trans-heptaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine => 5-methoxy-2-methyl-3-(all-trans-heptaprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)


name: Oxytocin receptor bind oxytocin (Canis familiaris)


name: Interaction between two DNA-PK:DNA complexes at opposing ends of DNA DSB (Gallus gallus)


name: Co-precorrin-7 + S-adenosyl-L-methionine <=> Co-precorrin-8X + S-adenosyl-L-homocysteine + H(+)


name: Co-precorrin-6B + S-adenosyl-L-methionine => Co-precorrin-7 + S-adenosyl-L-homocysteine + CO2


name: DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Bos taurus)


name: L-lysyl-tRNA(Lys) + a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) => a 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-lysyl)-sn-glycerol + tRNA(Lys)


name: glyceollin I + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => (6aS,11aS)-4-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced [NADPH--hemoprotein reductase] + O2


name: 19-hydroxy-11-deoxycorticosterone + 2 reduced [adrenodoxin] + O2 + 2 H(+) <=> 19-oxo-11-deoxycorticosterone + 2 oxidized [adrenodoxin] + 2 H2O


name: Thrombin-activated PARs binds G-protein Gq (Sus scrofa)


name: AVPR1A,2 bind AVPR antagonists (Danio rerio)


name: CYP3A4,5 oxidise AFB1 to AFXBO (Rattus norvegicus)


name: Formation of HIF:CBP:p300 complex at promoters (Gallus gallus)


name: (+)-valencene + diphosphate => (2E,6E)-farnesyl diphosphate


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Homo sapiens)


name: Phosphorylation of beta and gamma subunits by LYN (Sus scrofa)


name: a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine => an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP


name: carbon disulfide + H2O = carbonyl sulfide + hydrogen sulfide + H(+)


name: N-acetyl-D-glucosamine + GTP <=> N-acetyl-D-glucosamine 6-phosphate + GDP + H(+)


name: Duplex miRNA is loaded into Argonaute (Rattus norvegicus)


name: L-cysteine + L-glutamate + ATP <=> gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)


name: N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine + H(+) => L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine


name: 3-O-alpha-D-glucosyl-L-rhamnose + phosphate => beta-D-glucose 1-phosphate + L-rhamnopyranose


name: Src activation following P2Y purinoceptor activation (Homo sapiens)


name: Methylation of GMP-cap by RNA Methyltransferase (Dictyostelium discoideum)


name: alpha-linked polysaccharide catabolism to maltopentaose


name: TBC1D14 binds RAB11 and ULK1 (Caenorhabditis elegans)


name: oxalate(in) + formate(out) = oxalate(out) + formate(in)


name: Importin-8 imports AGO2:miRNA into the nucleus (Homo sapiens)


name: 2-hexadecanoylglycerol + H2O <=> glycerol + hexadecanoate + H(+)


name: coenzyme M-coenzyme B heterodisulfide + succinate => coenzyme B + coenzyme M + fumarate


name: NAD(+) <=> ADP-1-deoxy-1,O(4)-didehydro-D-ribose + nicotinamide


name: (2E)-geranyl diphosphate = alpha-thujene + diphosphate


name: Phosphorylation of 4E-BP1 by activated mTORC1 (Danio rerio)


name: a ganglioside GA2 (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GA1 (d18:1(4E)) + UDP + H(+)


name: Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Bos taurus)


name: L-tyrosine transmembrane transporter activity


name: (d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Rattus norvegicus)


name: estrone + 3'-phosphoadenylyl sulfate = estrone 3-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: RHOA binds effectors at the ER membrane (Gallus gallus)


name: a reduced flavin + NAD(+) = an oxidized flavin + NADH + 2 H(+)


name: Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation<br> (Canis familiaris)


name: SUMOylation of Histone H4 with SUMO3 (Dictyostelium discoideum)


name: GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Mus musculus)


name: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate


name: 2-phenylethylamine + A + H2O = 2-phenylacetaldehyde + AH2 + NH4(+)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Bos taurus)


name: KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Homo sapiens)


name: glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine = glycin-2-yl radical-[formate C-acetyltransferase] + semiquinone [flavodoxin] + 5'-deoxyadenosine + L-methionine + H(+)


name: DLAT trimer transfers acetyl to CoA (Rattus norvegicus)


name: SALMs 1-3 bind to PSD-95 family members (Sus scrofa)


name: L-seryl-[protein] + tetradecanoyl-CoA <=> O-tetradecanoyl-L-seryl-[protein] + CoA


name: N-hexadecanoylsphing-4-enine + ATP <=> N-(hexadecanoyl)-sphing-4-enine-1-phosphate + ADP + H(+)


name: regulation of phosphodiesterase I activity


name: USP19 binds HIF1A,BIRC2,BIRC3 (Bos taurus)


name: thiocyanate + 2 Fe(III)-[cytochrome c] + H2O = cyanate + sulfur + 2 Fe(II)-[cytochrome c] + 2 H(+)


name: dammarenediol-II + reduced [NADPH--hemoprotein reductase] + O2 = (20S)-protopanaxadiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: O-sinapoylcholine + H2O <=> (E)-sinapate + choline + H(+)


name: RAC3 GAPs stimulate RAC3 GTPase activity (Mus musculus)


name: a ganglioside GD1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GT1a (d18:1(4E)) + CMP + H(+)


name: thiamine diphosphate + ADP <=> thiamine triphosphate + AMP


name: 3-methylundecanoyl-CoA + 2 malonyl-CoA + 2 H(+) => 4-hydroxy-6-(2-methyldecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: histamine + L-glutamate + ATP => N(alpha)-gamma-L-glutamylhistamine + ADP + phosphate + H(+)


name: ATPase-coupled potassium transmembrane transporter activity


name: 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+) => 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein]


name: a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine => a 1-O-alkyl-2-acetyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: chrysobactin transmembrane transporter activity


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA => 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: ATG16L1 complex transfers LC3 from ATG3 to PE (Dictyostelium discoideum)


name: streptothricin D + acetyl-CoA <=> N(beta)-acetylstreptothricin D + CoA + H(+)


name: Aquaporins passively transport glycerol out of cells (Xenopus tropicalis)


name: 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+) => a 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O


name: 3,4-dihydroxyphenylacetyl-CoA + H2O = 3,4-dihydroxyphenylacetate + CoA + H(+)


name: tobramycin + carbamoyl phosphate + ATP + H2O <=> nebramycin 5' + AMP + phosphate + diphosphate + H(+)


name: D-iditol + NAD(+) => keto-D-sorbose + NADH + H(+)


name: regulation of potassium:proton exchanging ATPase activity


name: dopamine + S-adenosyl-L-methionine = 4-methoxytyramine + S-adenosyl-L-homocysteine + H(+)


name: methylmalonyl-CoA + octadecanoyl-CoA + malonyl-CoA + 2 H(+) <=> 4-hydroxy-5-methyl-6-heptadecylpyran-2-one + 2 CO2 + 3 CoA


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Mus musculus)


name: Conversion of glyoxylate to oxalate (Rattus norvegicus)


name: GRK1,4,7 phosphorylate MII to p-MII (Sus scrofa)


name: O-(5'-adenylyl)-L-tyrosyl-[protein] + ATP => O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein] + diphosphate


name: Insertion of correct bases opposite the lesion by POLH (Mus musculus)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Rattus norvegicus)


name: The keratan chain can be capped by N-acetylneuraminic acid (Homo sapiens)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains (Gallus gallus)


name: MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Bos taurus)


name: a 2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine => a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: ME1 tetramer decarboxylates OA to PYR (Canis familiaris)


name: Proteolytic processing of SLIT (Homo sapiens)


name: CAK-mediated phosphorylation of Cyclin A:Cdk2 (Bos taurus)


name: CYP3A4 can N-demethylate loperamide (Sus scrofa)


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Mus musculus)


name: Activation of EPACs by cAMP (Mus musculus)


name: 1-O-[(E)-feruloyl]-beta-D-glucose + UDP => (E)-ferulate + UDP-alpha-D-glucose


name: TP53 binds the CASP6 gene (Homo sapiens)


name: PTPN1 and PTPN2 dephosphorylate MET (Sus scrofa)


name: hexacosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) => (2E)-hexacosenoyl-CoA + reduced [electron-transfer flavoprotein]


name: 3-oxo-(5Z-tetradecenoyl)-CoA + NADH + H(+) => (3S)-hydroxy-(5Z-tetradecenoyl)-CoA + NAD(+)


name: factor V -> factor Va + factor V activation peptide (Mus musculus)


name: (2E,6E)-farnesyl diphosphate => alpha-guaiene + diphosphate


name: short-chain fatty acyl-CoA dehydrogenase activity


name: N-acetyltyramine + CoA + H(+) => tyramine + acetyl-CoA


name: ALK fusions phosphorylate PLCG1 (Homo sapiens)


name: ATP2A1-3 transport cytosolic Ca2+ to dense tubular network lumen (Caenorhabditis elegans)


name: nitrilotriacetate + FMNH2 + O2 => aminodiacetate + FMN + glyoxylate + H2O


name: activation of iron-sulfur-molybdenum cofactor assembly


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Canis familiaris)


name: EGR1 binds to the EGR1 promoter (Homo sapiens)


name: Thiosulfate can transfer its sulfur atom to glutathione (Sus scrofa)


name: SEMA4D interacts with Plexin-B1:Met (Caenorhabditis elegans)


name: catechol + CO2 => 2,3-dihydroxybenzoate + H(+)


name: queuosine(34) in tRNA(Tyr) + UDP-alpha-D-galactose => O-5''-beta-D-galactosylqueuosine(34) in tRNA(Tyr) + UDP + H(+)


name: glucokinase [nucleoplasm] => glucokinase [cytosol] (Caenorhabditis elegans)


name: MARK3 phosphorylates KSR1 (Canis familiaris)


name: precorrin-1 + S-adenosyl-L-methionine => precorrin-2 + S-adenosyl-L-homocysteine


name: a 3-oxo-fatty acyl-CoA + NADPH + H(+) <=> a 3-hydroxy-fatty acyl-CoA + NADP(+)


name: nsp10:nsp14 binds to ExoN inhibitors (Homo sapiens)


name: CDH11 associates with catenins (Gallus gallus)


name: ALDH8A1 oxidises 9cRAL to 9cRA (Mus musculus)


name: SLC38A9 binds Ragulator:Rag dimers (Rattus norvegicus)


name: PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA (Mus musculus)


name: deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Sus scrofa)


name: N(6)-methyladenosine(1832) in 18S rRNA + S-adenosyl-L-homocysteine + H(+) => adenosine(1832) in 18S rRNA + S-adenosyl-L-methionine


name: BTN2A1 binds DC-SIGN (Xenopus tropicalis)


name: SLC17A5 cotransports Neu5Ac, H+ from lysosomal lumen to cytosol (Xenopus tropicalis)


name: a beta-D-glucosylceramide(in) <=> a beta-D-glucosylceramide(out)


name: PTTG1 (Securin) sequesters ESPL1 (Separase) (Sus scrofa)


name: SLP-76 stimulates PLC gamma 2 (Rattus norvegicus)


name: Activated FGFR1 binds SHC1 (Rattus norvegicus)


name: (3R)-3-hydroxybutanoyl-CoA + NADP(+) => acetoacetyl-CoA + NADPH + H(+)


name: 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + NADH + H(+) => 12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD(+)


name: O-beta-D-xylosylzeatin + UDP + H(+) => zeatin + UDP-alpha-D-xylose


name: P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Rattus norvegicus)


name: 20-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2


name: trans-4-coumaroylshikimate + CoA => shikimate + 4-coumaroyl-CoA


name: DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)


name: Trans-autophosphorylation of EGFRvIII mutant dimers (Homo sapiens)


name: octanoyl-CoA + H2O = octanoate + CoA + H(+)


name: PDGFR mutants bind type I TKIs (Homo sapiens)


name: RTC completes synthesis of the minus strand genomic RNA complement (Homo sapiens)


name: Beta-catenin migrates to the nucleus (Drosophila melanogaster)


name: 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA (Mus musculus)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII (Canis familiaris)


name: GPR183 binds 7alpha,25-dihydroxycholesterol (Canis familiaris)


name: 5,6-dihydrouridine(17) in tRNA + NADP(+) <=> uridine(17) in tRNA + NADPH + H(+)


name: multicatalytic endopeptidase complex activity


name: UCHL1, UCHL3 cleave ubiquitin adducts (Dictyostelium discoideum)


name: 2-deoxy-L-scyllo-inosose + phosphate => D-glucose 6-phosphate


name: regulation of aspartic-type peptidase activity


name: Integrin alphaMbeta2 (MAC1) binds JAM3 (Canis familiaris)


name: MAPK1-dependent phosphorylation of MITF-M (Saccharomyces cerevisiae)


name: 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate => 2 5-dehydro-4-deoxy-D-glucuronate


name: minor histocompatibility antigen activity


name: JAK2-activated MAPKs phosphorylate YBX1 (Danio rerio)


name: all-trans-18-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => all-trans-retinoate + reduced [NADPH--hemoprotein reductase] + O2


name: UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose (Danio rerio)


name: CHRM4 binds CHRM4 antagonists (Drosophila melanogaster)


name: 5-oxohexanoate + H(+) => cyclohexane-1,3-dione + H2O


name: G alpha (12/13) auto-inactivates by hydrolysing GTP to GDP (Dictyostelium discoideum)


name: an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + CoA => an anthocyanidin 3-O-beta-D-glucoside + malonyl-CoA


name: 3-deacetyl-3-(1-hydroxyethyl)bacteriochlorophyllide a + NAD(+) = bacteriochlorophyllide a + NADH + H(+)


name: inhibition of intracellular signal transduction


name: Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Homo sapiens)


name: Nociceptin receptor binds to nociceptin (Homo sapiens)


name: Phosphorylation of Smooth Muscle Myosin Light Chains (Bos taurus)


name: PAH:Fe2+ tetramer hydroxylates L-Phe to L-Tyr (Dictyostelium discoideum)


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate


name: HERC2 and PIAS4 are recruited to DNA DSBs (Drosophila melanogaster)


name: beta-casomorphin-7 + H2O => beta-casomorphin-6 + L-isoleucine


name: 3'-dehydromaltose + H2O <=> 3-dehydro-D-glucose + D-glucose


name: DHFR dimer binds DHFR inhibitors (Dictyostelium discoideum)


name: (d)NTP + ADP <=> (d)NDP + ATP (NME4) (Plasmodium falciparum)


name: Recruitment of DNA2 endonuclease to the C strand (Homo sapiens)


name: L-cysteine + ATP + H(+) <=> L-cysteinyl-5'-AMP + diphosphate


name: fusoxypene A + diphosphate => (2E,6E,10E,14E)-geranylfarnesyl diphosphate


name: pentanoate + an aliphatic alcohol + H(+) => pentanoate ester + H2O


name: PARP1 binds SMAD2/3:SMAD4 heterotrimer (Rattus norvegicus)


name: YWHAB dimer dissociates from KSR1:MARK3 (Caenorhabditis elegans)


name: 2-sulfamoylacetate + holo-[peptidyl-carrier protein] + ATP <=> 2-sulfamoylacetyl-[peptidyl-carrier protein] + AMP + diphosphate


name: Binding of ADAR2 homodimer to dsRNA duplex (Mus musculus)


name: SUMOylation of DNMT3B with SUMO1 (Mus musculus)


name: G alpha (q) auto-inactivates by hydrolysing GTP to GDP (Sus scrofa)


name: (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + tetradecanoyl-[ACP] => ((9Z)-hexadecenoyl-tetradecanoyl)-(Kdo)2-lipid A + holo-[ACP]


name: TYRP1 oxidises DHICA to IQCA (Danio rerio)


name: an (E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amine + H2O2 + H(+) => an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + O2


name: 2-phenylacetaldehyde + hydrogen cyanide = (2S)-2-hydroxy-3-phenylpropanenitrile


name: Interaction of other tyrosine kinases with p-KIT (Rattus norvegicus)


name: 11-hydroxyferruginol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = carnosate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: COMP binds collagen, fibronectin, aggrecan and matrilins (Danio rerio)


name: PAK1-3 dimer disassociates (Drosophila melanogaster)


name: DLD dimer dehydrogenates dihydrolipoyl (Mus musculus)


name: Cleavage of ethenoadenine by MPG glycosylase (Rattus norvegicus)


name: GLB1 hydrolyzes SapB/C:LacCer (Canis familiaris)


name: apigenin + reduced [NADPH--hemoprotein reductase] + O2 = luteolin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Recruitment of PAK to the membrane by binding active RAC1 (Drosophila melanogaster)


name: Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation  (Sus scrofa)


name: HSD17B3,12 hydrogenates 3OOD-CoA to 3HODC-CoA (Danio rerio)


name: 5-methylcytidine(50) in tRNA + S-adenosyl-L-homocysteine + H(+) => cytidine(50) in tRNA + S-adenosyl-L-methionine


name: a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O <=> a 5'-end phospho-ribonucleoside in mRNA + NAD(+) + H(+)


name: D-glyceraldehyde + ATP <=> D-glyceraldehyde 3-phosphate + ADP + H(+)


name: (2E)-3-methyl-5-phosphooxypent-2-enoate + H(+) => isopentenyl phosphate + CO2


name: L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2


name: a 2-oxocarboxylate + H2O2 + NH4(+) => an L-alpha-amino acid + O2 + H2O


name: geranylgeranyl diphosphate + 3 NADPH + 3 H(+) => phytyl diphosphate + 3 NADP(+)


name: 3,3'-diiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) <=> 3,3'-diiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)


name: Dissociation of Arf1:GDP, AP-1 Clathrin coated nonameric complex (Rattus norvegicus)


name: reduced coenzyme F420:quinone oxidoreductase activity


name: Autophosphorylation of PKC-theta (Mus musculus)


name: geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate


name: Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Gallus gallus)


name: Formation of P-TEFb complex (Saccharomyces cerevisiae)


name: Factor IIa inhibitors (peptide) binds IIa (Mus musculus)


name: S-disulfanyl-L-cysteinyl-[SoxY protein] + 6 Fe(III)-[cytochrome c] + 3 H2O = S-sulfosulfanyl-L-cysteinyl-[SoxY protein] + 6 Fe(II)-[cytochrome c] + 7 H(+)


name: ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Canis familiaris)


name: IRAK1 induces oligomerisation of TRAF6 (Sus scrofa)


name: ATM dimer:p-PEX5 ubiquitinates to form ATM dimer:Ub-p-PEX5 (Rattus norvegicus)


name: PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate (Xenopus tropicalis)


name: L-cysteine + ATP + H(+) = L-cysteinyl-5'-AMP + diphosphate


name: 1,3-di-(9Z)-octadecenoyl-2-hexadecanoylglycerol + H2O = 2-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)


name: pyrazinamide + H2O => pyrazine-2-carboxylate + NH4(+)


name: CTNS cotransports CySS-, H+ from lysosomal lumen to cytosol (Dictyostelium discoideum)


name: p-ULK1 phosphorylates DENND3 (Schizosaccharomyces pombe)


name: Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA (Danio rerio)


name: 5,6-dihydrouridine(20) in tRNA + NADP(+) = uridine(20) in tRNA + NADPH + H(+)


name: PAK1-3 autophosphorylates (Homo sapiens)


name: L-erythro-biopterin + 2 NADPH + 2 H(+) => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP(+)


name: GNE phosphorylates ManNAc to ManNAc-6-P (Bos taurus)


name: CREBBP acetylates HINT1 dimer (Gallus gallus)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Bos taurus)


name: UBA1 conjugates ubiquitin to nuclear E2 enzymes (Homo sapiens)


name: adenylosuccinate => adenosine 5'-monophosphate + fumarate (Bos taurus)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Sus scrofa)


name: [eIF5A protein]-L-lysine + [deoxyhypusine synthase]-N-(4-aminobutylidene)-L-lysine <=> [deoxyhypusine synthase]-L-lysine + [eIF5A protein]-N-(4-aminobutylidene)-L-lysine


name: 1-hexadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol => (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Frataxin transfers Fe2+ to ACO2 (Schizosaccharomyces pombe)


name: N-acetyl-D-glucosamine + CTP = N-acetyl-D-glucosamine 6-phosphate + CDP + H(+)


name: NCOA1 recruits EP300 to TGFA promoter (Rattus norvegicus)


name: a fatty acid + ATP + H(+) = a fatty acyl-AMP + diphosphate


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + ATP <=> 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+)


name: IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Mus musculus)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Sus scrofa)


name: Formation of PPARG:RXRA heterodimer (ARF6 complex) (Rattus norvegicus)


name: jasmonate + 2-oxoglutarate + O2 <=> (1R,2R)-12-hydroxyjasmonate + succinate + CO2


name: (R)-6-hydroxynicotine + O2 = 6-hydroxy-N-methylmyosmine + H2O2


name: tigogenin 3-O-beta-D-glucopyranoside + UDP + H(+) => tigogenin + UDP-alpha-D-glucose


name: SLC35C1 transport UDP-Fuc from cytosol to Golgi lumen (Rattus norvegicus)


name: Interaction of DAP12 and TREM2 (Mus musculus)


name: SOS-mediated nucleotide exchange of RAS downstream of mutant PDGFR receptors (Homo sapiens)


name: SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Mus musculus)


name: glycylglycyl-L-isoleucine(out) + H(+)(out) <=> glycylglycyl-L-isoleucine(in) + H(+)(in)


name: Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Bos taurus)


name: DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Saccharomyces cerevisiae)


name: hexanoyl-CoA + AMP + diphosphate => hexanoate + ATP + CoA


name: PIAS1,4 SUMOylate CASP8AP2 with SUMO1 (Homo sapiens)


name: 1-O-hexadecyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)


name: 3-(2-methylsulfanyl)ethylmalate => 2-(2-methylsulfanyl)ethylmaleate + H2O


name: RBX1:CUL3 dissociates from forming autophagosome (Mus musculus)


name: (2S)-ethylmalonyl-CoA + H(+) = butanoyl-CoA + CO2


name: hydrogen sulfide + formaldehyde + H2O2 + H(+) => methanethiol + O2 + H2O


name: MTA is cleaved and phosphorylated (Danio rerio)


name: 3-(methylsulfanyl)propanoyl-CoA + butan-1-ol => butyl 3-(methylsulfanyl)propanoate + CoA


name: Activated FGFR1:p-FRS:GRB2:SOS1 activates RAS nucleotide exchange (Mus musculus)


name: GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Rattus norvegicus)


name: RHOA binds effectors at the plasma membrane (Danio rerio)


name: hexadecan-1-ol + octadecanoyl-CoA = hexadecanyl octadecanoate + CoA


name: SUMOylation of TOP2B with SUMO1 (Caenorhabditis elegans)


name: an aromatic L-alpha-amino acid(in) + 3,3',5-triiodo-L-thyronine(out) <=> an aromatic L-alpha-amino acid(out) + 3,3',5-triiodo-L-thyronine(in)


name: itaconate(in) + 3 Na(+)(in) => itaconate(out) + 3 Na(+)(out)


name: high-affinity D-glucose:proton symporter activity


name: high-affinity glucose:proton symporter activity


name: Translocation of p27 to the nucleoplasm (Danio rerio)


name: PAFAH2 hydrolyses PAF to lyso-PAF and acetate (Sus scrofa)


name: positive regulation of receptor recycling


name: M6PR transports activated ARSA to the lysosome (Sus scrofa)


name: 26-hydroxylanosterol + reduced [NADPH--hemoprotein reductase] + O2 => 26-oxolanosterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: Aquaporin-1 passively transports water into cell (Mus musculus)


name: NRP-2 associates with VEGFR1 forming complexes on  cell surface (Gallus gallus)


name: I(1,3,4,5,6)P5 is dephosphorylated to I(1,4,5,6)P4 by MINPP1 in the ER lumen (Mus musculus)


name: down regulation of amyloid structure formation


name: Formation of the Flap Intermediate on the C-strand (Canis familiaris)


name: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2


name: BTG2 binds CCR4-NOT complex (Dictyostelium discoideum)


name: gibberellin A9 + S-adenosyl-L-methionine = O-methyl gibberellin A9 + S-adenosyl-L-homocysteine


name: (2E)-geranyl diphosphate <=> (4R)-limonene + diphosphate


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-O-hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + sn-glycerol 3-phosphocholine


name: NLRC5 binds IKBKB and CHUK (Rattus norvegicus)


name: Antizyme inhibitor binds to OAZ and stablizes ODC complex (Canis familiaris)


name: Increased Peripheral Nervous System Nerve Growth Factor Activity


name: N-(8'-oxogeranyl)-L-glutamate + reduced [NADPH--hemoprotein reductase] + O2 <=> N-(7'-carboxy-7'-demethylgeranyl)-L-glutamate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: PEX7 binds cargo proteins containing PTS2 (Drosophila melanogaster)


name: o-quinone methide + ethanol = hydroxyclavatol ethyl ether


name: N,N-dimethyl-1,4-phenylenediamine + anthranilate + 2 NAD(+) => 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 NADH + 2 H(+)


name: AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG (Bos taurus)


name: N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O => N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoate + H(+)


name: Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Mus musculus)


name: ent-copalyl diphosphate => ent-(12E)-labda-8(17),12,14-triene + diphosphate


name: Binding of acetylcholine to highly sodium permeable postsynaptic acetylcholine receptors (Rattus norvegicus)


name: Activation of Ca2+ activated Potassium channels with small conductance (Caenorhabditis elegans)


name: Glucagon binds to Glucagon receptor (Bos taurus)


name: PIAS1 SUMOylates THRB with SUMO1 (Sus scrofa)


name: (R)-4-phosphopantoate + beta-alanine + ATP => (R)-4'-phosphopantothenate + AMP + diphosphate + H(+)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Mus musculus)


name: 3-(2-hydroxyphenyl)propanoate + NADH + O2 + H(+) = 3-(2,3-dihydroxyphenyl)propanoate + NAD(+) + H2O


name: 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: 1/3 PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Drosophila melanogaster)


name: urea + 2 H2O + H(+) <=> hydrogencarbonate + 2 NH4(+)


name: Corticosteroids bind to CBG in blood (Drosophila melanogaster)


name: ATXN3 family cleave Ub chains (Xenopus tropicalis)


name: GSTK1 dimer transfers GS from GSH to CDNB (Caenorhabditis elegans)


name: a beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H(+)


name: melanin-concentrating hormone receptor binding


name: 7,8-dihydroxykynurenate + NADH + H(+) => 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+)


name: ACLY tetramer transforms CIT to Ac-CoA (Xenopus tropicalis)


name: IL17RD binds p-2S MAP2Ks and MAPKs (Bos taurus)


name: JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)


name: PLK2 phosphorylates NPM1 (Canis familiaris)


name: ergosteryl ester + H2O => ergosterol + a carboxylate + H(+)


name: Prostate-specific Antigen proteolyzes IGF:IGFBP3:ALS  (Homo sapiens)


name: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate


name: 2alpha-hydroxyl, 4beta-carboxyl motiol + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = polytolypin + 4 oxidized [NADPH--hemoprotein reductase] + 5 H2O + 5 H(+)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Homo sapiens)


name: an alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP-alpha-D-mannose = an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + GDP + H(+)


name: ganglioside GM2 (d18:1(4E)/18:0) + CMP + H(+) => ganglioside GA2 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate


name: (2E,6E)-farnesyl diphosphate + H2O <=> (-)-alpha-acorenol + diphosphate


name: CD36 (FAT) translocates palmitate from the extracellular region to the cytosol (Caenorhabditis elegans)


name: Gamma-carboxy pro-factor IX transport from the endoplasmic reticulum to the Golgi apparatus (Sus scrofa)


name: 3,8-divinyl protochlorophyllide a + NADPH + H(+) => protochlorophyllide a + NADP(+)


name: ILK interacts with beta-1 integrin (Bos taurus)


name: PM20D1 transforms oleoyl-phe from oleate and phe (Sus scrofa)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Bos taurus)


name: phosphinate(out) + ATP + H2O = phosphinate(in) + ADP + phosphate + H(+)


name: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA => 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O


name: PAK1 autophosphorylates (Xenopus tropicalis)


name: XDH dehydrogenates xanthine to form urate (Canis familiaris)


name: Cleavage of Intronless Pre-mRNA at 3'-end (Gallus gallus)


name: TRPV4 tetramer binds CALM1:Ca2+ (calmodulin:Ca2+) (Canis familiaris)


name: L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+)


name: 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O (Mus musculus)


name: ST3GAL1-6 transfer Neu5Ac to terminal Gal (alpha-2,3 link) (Canis familiaris)


name: Secreted CD14 binds LPS (Canis familiaris)


name: Activated FGFR4:p-SHC1 binds GRB2:SOS1 (Gallus gallus)


name: DPP4 binds DPP4 inhibitors (Caenorhabditis elegans)


name: Association of procollagen type XVIII (Sus scrofa)


name: D-ribulose + ATP <=> D-ribulose 5-phosphate + ADP + H(+)


name: Phosphorylation of Platelet Sec-1 (Schizosaccharomyces pombe)


name: Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B (Sus scrofa)


name: POLZ elongates POLI-incorporated dNMP (Drosophila melanogaster)


name: PDE6 hydrolyses cGMP to GMP (Mus musculus)


name: 1-hexadecanoylglycerol + (9Z)-octadecenoyl-CoA => 1-hexadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine <=> a 3-O-{[alpha-Neu5Ac-(2->3)]-beta-D-GalNAc-(1->4)-beta-D-Gal-(1->3)-[alpha-Neu5Ac-(2->6)]-alpha-D-GalNAc}-L-threonyl-[protein] + UDP + H(+)


name: RIPK3 phosphorylates MLKL (Rattus norvegicus)


name: MDH2 dimer dehydrogenates MAL (Bos taurus)


name: MigFilin associates with Filamin and F-actin (Drosophila melanogaster)


name: a ganglioside Gal-GD1b (d18:1(4E)) + UDP-alpha-D-galactose => a ganglioside GalGal-GD1b (d18:1(4E)) + UDP + H(+)


name: lipid A hexaacyl 1-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) <=> lipid A 1,4'-bis(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol


name: 4-hydroxy-6-(13-hydroxy-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA => 12-hydroxyoctadecanoyl-CoA + 3 malonyl-CoA + 3 H(+)


name: GNRHR binds GNRHR peptide agonists (Drosophila melanogaster)


name: anthraniloyl-CoA + 2 NADPH + O2 + 2 H(+) = 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 NADP(+) + H2O


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+) => 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH


name: PIAS4 SUMOylates PARP1 with SUMO2,3 (Xenopus tropicalis)


name: deoxyviolacein + CO2 + NAD(+) + 2 H2O => protodeoxyviolaceinate + NADH + 2 O2 + 2 H(+)


name: Pregn-5-ene-3,20-dione isomerizes to progesterone (Danio rerio)


name: (E)-caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+)


name: (E)-ferulate + UDP-alpha-D-glucuronate = (E)-4-O-(beta-D-glucuronosyl)-ferulate + UDP + H(+)


name: SLC2A6,8,10,12 transport Glc from extracellular region to cytosol (Canis familiaris)


name: p-4Y-SIRPA:CD47:SKAP2 binds FYB (Mus musculus)


name: anthranilate + ATP + H(+) = 2-aminobenzoyl-AMP + diphosphate


name: positive regulation of co-chaperone activity


name: CHOL translocates from cytosol to mitochondrial intermembrane space (Homo sapiens)


name: Caspase-mediated cleavage of E-Cadherin (Drosophila melanogaster)


name: POLL or POLM extends aligned DNA DSB ends to fill gaps (Canis familiaris)


name: di-trans,nona-cis-dodecaprenyl diphosphate + 9 diphosphate => (2Z,6E)-farnesyl diphosphate + 9 isopentenyl diphosphate


name: RNA Polymerase III Abortive Initiation At Type 2 Open Promoters (Homo sapiens)


name: Histone H2A is dubiquitinated by the PR-DUB complex (Rattus norvegicus)


name: xylitol + NADP(+) => D-xylose + NADPH + H(+)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Drosophila melanogaster)


name: PIAS4 SUMOylates VHL with SUMO1 (Gallus gallus)


name: androstan-3alpha,17beta-diol + NAD(+) <=> 17beta-hydroxyandrostanone + NADH + H(+)


name: [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + NADPH + H(+) => [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + phosphate + NADP(+)


name: GAL3ST1 transfers sulfate to GalCer,LacCer (Sus scrofa)


name: IL21 receptor JAK phosphorylation (Homo sapiens)


name: urea + beta-alanine => 3-guanidinopropanoate + H2O


name: 1-O-(trans-sinapoyl)-beta-D-glucose + choline <=> O-sinapoylcholine + D-glucose


name: 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 <=> 2 L-citrulline + 2 nitric oxide + NAD(+) + 2 H2O + H(+)


name: (R)-malate + NAD(+) => pyruvate + CO2 + NADH


name: MHC Class I interacts with CD160 (Canis familiaris)


name: preaustinoid A2 + 2-oxoglutarate + O2 = preaustinoid A3 + succinate + CO2 + H2O


name: (E)-4-coumarate + H2O = 3-hydroxy-3-(4-hydroxyphenyl)propanoate


name: 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-(N-9Z-octadecenoyl)-ethanolamine + H2O => 1-O-(1Z-octadecenyl)-sn-glycero-3-phosphate + N-(9Z-octadecenoyl) ethanolamine + H(+)


name: 6-deoxotyphasterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 3-epi-6-deoxocathasterone + reduced [NADPH--hemoprotein reductase] + O2


name: BAR domain proteins recruit dynamin (Drosophila melanogaster)


name: a fatty acyl-CoA + H2O <=> a fatty acid + CoA + H(+)


name: CO binds to Cytochrome c oxidase (Drosophila melanogaster)


name: Single mechanism MAPK inhibitors bind phosphorylated MAPK (Sus scrofa)


name: L-5-[2-(methysulfanyl)ethyl]hydantoin + H2O = N-carbamoyl-L-methionine + H(+)


name: pyridoxine 5'-phosphate + H2O <=> pyridoxine + phosphate


name: 3-phosphooxypyruvate + L-glutamate => O-phospho-L-serine + 2-oxoglutarate


name: (-)-alpha-cedrene + diphosphate => (2Z,6Z)-farnesyl diphosphate


name: furfural + hydrogen cyanide <=> (2R)-2-(furan-2-yl)-2-hydroxyacetonitrile


name: (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + NADH + H(+)


name: N-tetradecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-tetradecanoylethanolamine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: "endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase"


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + reduced [NADPH--hemoprotein reductase] + O2 <=> 1-[(9R,10S)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)


name: AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: heptanedioate + ATP + CoA <=> 6-carboxyhexanoyl-CoA + AMP + diphosphate


name: 2,4,6-trinitrotoluene + 2 NADH + 2 H(+) = 2-hydroxylamino-4,6-dinitrotoluene + 2 NAD(+) + H2O


name: a Delta(14) steroid + formate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+) => a 14alpha-methyl steroid + 3 reduced [NADPH--hemoprotein reductase] + 3 O2


name: 2-methoxy-6-(all-trans-octaprenyl)phenol + prephenate + A + H(+) => 2-methoxy-6-(all-trans-octaprenyl)benzene-1,4-diol + 3-phenylpyruvate + AH2 + CO2


name: (E)-phenylacetaldehyde oxime + reduced [NADPH--hemoprotein reductase] + O2 = 1-aci-nitro-2-(phenyl)ethane + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: phosphonoacetate + H2O = acetate + phosphate + H(+)


name: (8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate <=> 8,9-epoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O


name: 1,2-didodecanoyl-3-beta-D-galactosyl-sn-glycerol + H2O <=> dodecanoyl-3-beta-D-galactosyl-sn-glycerol + dodecanoate + H(+)


name: type 2 proteinase activated receptor binding


name: protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Saccharomyces cerevisiae)


name: Activated FGFR1 binds PLCG1 (Canis familiaris)


name: 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA => (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + a 1-acyl-sn-glycero-3-phosphocholine


name: PP2A-PP2R5C dephosphorylates MDM2 (Homo sapiens)


name: phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate (Homo sapiens)


name: 3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)


name: CHEK1 phosphorylates RAD51 (Caenorhabditis elegans)


name: prop-2-ynal + pyrroloquinoline quinol + H(+) <=> prop-2-yn-1-ol + pyrroloquinoline quinone


name: Deubiquitination of RNF41 by P-USP8 (Homo sapiens)


name: a 2-oxocarboxylate + NADH + H(+) => a (2R)-2-hydroxycarboxylate + NAD(+)


name: SLC31A1 transports Cu2+ from extracellular region to cytosol (Caenorhabditis elegans)


name: CyP60 chaperones Basigin (Drosophila melanogaster)


name: AURKB phosphorylates DIAPH2-2 at kinetochores (Sus scrofa)


name: 16alpha,17beta-estriol + UDP-alpha-D-glucuronate <=> 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + UDP + H(+)


name: TLR9 processing at neutral pH (Canis familiaris)


name: SDK2 homophillic interaction (Bos taurus)


name: L-alanyl-L-leucine(out) + ATP + H2O = L-alanyl-L-leucine(in) + ADP + phosphate + H(+)


name: SQSTM1 binds ATM dimer:Ub-p-PEX5 (Sus scrofa)


name: D-glucuronate + H2O + H(+) => myo-inositol + O2


name: Nucleotide exchange on RAB1 (Sus scrofa)


name: (3R)-hydroxytetradecanoyl-[ACP] <=> (2E)-tetradecenoyl-[ACP] + H2O


name: active ion transmembrane transporter activity


name: 4-prenylphlormethylbutanophenone + dimethylallyl diphosphate <=> deoxyadlupulone + diphosphate


name: extracellular matrix structural constituent


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Gallus gallus)


name: Internalization of MHC II:Ii clathrin coated vesicle (Mus musculus)


name: Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Drosophila melanogaster)


name: Relocalization of nuclearly localized phospho-(T286):cyclin D1:Cdk4 to cytoplasm (Rattus norvegicus)


name: a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + H(+) = a 2-(all-trans-polyprenyl)phenol + CO2


name: FAHD1 dimer hydrolyses OA to PYR (Sus scrofa)


name: ATM phosphorylates WHSC1 (Dictyostelium discoideum)


name: MET dimers autophosphorylate (Gallus gallus)


name: anthraniloyl-CoA + 2 NADH + O2 + 2 H(+) => 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 NAD(+) + H2O


name: 2-oxobutanoate + L-tyrosine = (2S)-2-aminobutanoate + 3-(4-hydroxyphenyl)pyruvate


name: USP16,USP21 deubiquitinate Histone H2A (Homo sapiens)


name: N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2


name: neurotensin-(1-12) + L-leucine => neurotensin + H2O


name: Proteasome mediated degradation of COP1 (Dictyostelium discoideum)


name: 2-methylpentadecanal + formyl-CoA => 2-hydroxy-3-methylhexadecanoyl-CoA


name: Conversion of Glycerol to Glycerol-3-phosphate (Rattus norvegicus)


name: ESR1:ESTG:PGR:P4 bind pioneer factors and coactivators (Sus scrofa)


name: 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoate + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + catechol + H(+)


name: 3-ketopristanoyl-CoA + CoASH => 4,8,12-trimethyltridecanoyl-CoA + propionyl-CoA (Bos taurus)


name: Activation of p38 MAPK (Dictyostelium discoideum)


name: DPP4(1-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP) (Sus scrofa)


name: a ganglioside GD1a + H2O => a ganglioside GM1 + N-acetylneuraminate


name: negative regulation of vitamin D receptor signaling pathway


name: Release of GABA at the synapse (Canis familiaris)


name: SFTPD 12mer translocates from ER membrane to extracellular region (Mus musculus)


name: Interaction of SHP-1 or SHP-2 with phospho PD-1 (Bos taurus)


name: CHOL translocates from cytosol to mitochondrial intermembrane space (Danio rerio)


name: p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS (Drosophila melanogaster)


name: N-(2-hydroxytetracosanoyl)-sphinganine + CoA + H(+) => 2-hydroxytetracosanoyl-CoA + sphinganine


name: Ca impermeable AMPA receptor ligand binding (Caenorhabditis elegans)


name: PIAS1,4 SUMOylates BRCA1 with SUMO1 (Homo sapiens)


name: calcium-dependent protein serine/threonine phosphatase, intrinsic regulator activity


name: PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Drosophila melanogaster)


name: CUL1, SKP1, FBXL5 bind (Canis familiaris)


name: L-histidyl-L-proline diketopiperazine(in) => L-histidyl-L-proline diketopiperazine(out)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Epoxide hydrolase hydrolyses 16(S),17(S)-epoxy-DPAn-3 to PD1n-3DPA or PD2n-3DPA (Homo sapiens)


name: osmolarity-sensing monoatomic cation channel activity


name: SWI/SNF chromatin remodelling complex enhances MEP50:PRMT5 methyltransferase activity (Canis familiaris)


name: NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Xenopus tropicalis)


name: 5-hydroxykynurenamine + CO2 <=> 5-hydroxy-L-kynurenine + H(+)


name: cytidine 5'-diphosphoramidate + ATP = cytidine 3'-phospho-5'-diphosphoramidate + ADP + H(+)


name: MDM2 polyubiquitinates RUNX3 (Sus scrofa)


name: PI3P is dephosphorylated to PI by SYNJ/MTMs at the plasma membrane (Homo sapiens)


name: dodecan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,4-dodecanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Oxidative damage to the AP site (Canis familiaris)


name: a 1-acylglycerone 3-phosphate + CoA => dihydroxyacetone phosphate + an acyl-CoA


name: positive regulation of gastric H+/K(+) ATPase activity


name: Fibronectin degradation by CTSG (Bos taurus)


name: DDX41 ubiquitination by TRIM21 (Canis familiaris)


name: fraxetin + reduced [NADPH--hemoprotein reductase] + O2 => sideretin (reduced form) + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate => O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: HLA-C specific inhibitory MHC class I receptor activity


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Xenopus tropicalis)


name: PKA phosphorylates RET:GDNF:GFRA dimer (Bos taurus)


name: acetyl-CoA(in) + AMP(out) => acetyl-CoA(out) + AMP(in)


name: p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Danio rerio)


name: CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO (Bos taurus)


name: RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)


name: LIG3 ligates NEIL1,NEIL2-generated single strand break (Sus scrofa)


name: 14-hydroperoxy-(7Z,10Z,12E,16Z,19Z)-docosapentaenoate => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2


name: L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP + H(+) => L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP-L-glycero-beta-D-manno-heptose


name: 5alpha-ergosta-7,22-diene-3beta,5-diol => ergosterol + H2O


name: TPMT transfers CH3 from AdoMet to 6MP (Bos taurus)


name: N(6),N(6)-dimethyl-L-lysyl-[protein] + 2-oxoglutarate + O2 => N(6)-methyl-L-lysyl-[protein] + formaldehyde + succinate + CO2


name: Enolase dimers (ENO1,2,3) convert PEP to 2PG (Rattus norvegicus)


name: MAPK4,6 translocate to nucleus (Dictyostelium discoideum)


name: 2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + H2O + H(+) = 5-amino-6-(5-phospho-D-ribitylamino)uracil + NH4(+)


name: The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Homo sapiens)


name: L-phenylalanyl-L-phenylalanine(out) + H(+)(out) => L-phenylalanyl-L-phenylalanine(in) + H(+)(in)


name: PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)


name: a ribonucleoside 5'-triphosphate + H2O => a ribonucleoside 5'-diphosphate + phosphate + H(+)


name: 8-hydroxycopalyl diphosphate + H2O => sclareol + diphosphate


name: ZNRF3 autoubiquitinates to promote its internalization (Mus musculus)


name: Spermine  => N-acetylated spermine (Dictyostelium discoideum)


name: PSMG1:PSMG2 dimer binds the 20S core particle outer ring (Gallus gallus)


name: (R)-2-methylimino-1-phenylpropan-1-ol + NADH + 2 H(+) => (1R,2S)-ephedrine + NAD(+)


name: SLC12A4,5,6,7 cotransport K+, Cl- from cytosol to extracellular region (Canis familiaris)


name: MTTP lipidates APOB-100, forming a pre-VLDL (Bos taurus)


name: 5beta-dihydroepitestosterone + NADP(+) => epitestosterone + NADPH + H(+)


name: S-dodecanoyl-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => dodecanoyl-CoA + H2O


name: N-hexadecanoylethanolamine + H2O => ethanolamine + hexadecanoate


name: Translocation of ERBB4s80:YAP1 complex to the nucleus (Rattus norvegicus)


name: 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + H2O <=> a 2-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoate + H(+)


name: TP receptor can bind thromboxane (Drosophila melanogaster)


name: RIC1:RGP1 recruits RAB6:GDP to the TGN (Caenorhabditis elegans)


name: valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)


name: a flavanone + reduced [NADPH--hemoprotein reductase] + O2 <=> a 2-hydroxyflavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 4-hydroxycasbene + reduced [NADPH--hemoprotein reductase] + O2 <=> 4,8-dihydroxycasbene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: MAF1 translocates to the nucleus (Plasmodium falciparum)


name: PLC-gamma1 hydrolyses PIP2 (Canis familiaris)


name: SHP-1 and SHP-2 bind pBTLA (Canis familiaris)


name: FECH binds Fe2+ to PRIN9 to form heme (Homo sapiens)


name: O-propanoyl-(R)-carnitine(out) + Na(+)(out) <=> O-propanoyl-(R)-carnitine(in) + Na(+)(in)


name: RHOF GAPs stimulate RHOF GTPase activity (Caenorhabditis elegans)


name: saccharopine + NAD+ + H2O => alpha-aminoadipic semialdehyde + glutamate + NADH + H+ (Xenopus tropicalis)


name: KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer (Danio rerio)


name: all-trans-octaprenyl phosphate + ADP + H(+) => all-trans-octaprenol + ATP


name: ZNRF3 ubiquitinates FZD to promote its downregulation (Gallus gallus)


name: 3-hydroxyanthranilate + S-adenosyl-L-methionine => 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+)


name: inhibition of ceramide glucosidase activity


name: (2S)-2-hydroxy-3,4-dioxopentyl phosphate <=> 3-hydroxy-2,4-dioxopentyl phosphate


name: Hemagglutinin (HA) protein synthesis (Homo sapiens)


name: Loading of antigenic peptides (Xenopus tropicalis)


name: 3-dehydro-4-O-phospho-D-erythronate + H(+) <=> dihydroxyacetone phosphate + CO2


name: Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Bos taurus)


name: deoxylimononate D-ring-lactone + H(+) => deoxylimonoate + H2O


name: CBX3 and PRC1.6 associate with E2F6.com-1 (Homo sapiens)


name: SDBH (soluble dopamine beta-monooxygenase)


name: tellurite(in) + Na(+)(in) = tellurite(out) + Na(+)(out)


name: (2E)-butenoyl-CoA + (R)-carnitine = O-(2E)-butenoyl-(R)-carnitine + CoA


name: ARFGAP, cargo, vSNARES and p24 proteins bind COPI vesicles at Golgi (Sus scrofa)


name: glycerol + a fatty acid + H(+) => a monoacylglycerol + H2O


name: 3-(all-trans-decaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = 2-methoxy-6-(all-trans-decaprenyl)phenol + S-adenosyl-L-homocysteine + H(+)


name: decarboxylation-driven active transmembrane transporter activity


name: Putrescine + dc-Adenosyl methionine  => Spermidine + 5'-methylthioadenosine (Mus musculus)


name: 1-O-hexadecyl-sn-glycero-3-phosphoethanolamine + acetate + H(+) => 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine + H2O


name: beta-D-glucosyl-N-dodecanoylsphing-4-enine + cholesterol => N-dodecanoylsphing-4-enine + cholesteryl 3-beta-D-glucoside


name: Phosphorylated Orc1 is ubiquitinated while still associated with chromatin (Dictyostelium discoideum)


name: intracellular nucleoside transmembrane transporter activity


name: AVPR1A,2 bind AVPR antagonists (Homo sapiens)


name: Exocytosis of platelet alpha granule contents (Schizosaccharomyces pombe)


name: paromamine + UDP-alpha-D-glucose = 3''-deamino-3''-hydroxykanamycin C + UDP + H(+)


name: methylamine dehydrogenase (amicyanin) activity


name: Phosphorylation of STAT1 at Ser727 (Danio rerio)


name: BIRC2/3 (cIAP1/2) is autoubiquitinated (Mus musculus)


name: APC/C:Cdh1-mediated degradation of Skp2 (Bos taurus)


name: Retromer recycles WLS to the Golgi (Saccharomyces cerevisiae)


name: ESTG binds ESR2:chaperone complex (Bos taurus)


name: a ganglioside Ac-O-8-GD2 <=> a ganglioside Ac-O-9-GD2


name: Loading of PCNA - Sliding Clamp Formation on the C-strand of the telomere (Mus musculus)


name: Adenylate Kinase 3 is a GTP-AMP phosphotransferase (Saccharomyces cerevisiae)


name: PSMD14 cleaves K63-linked ubiquitin (Dictyostelium discoideum)


name: p62 binds ubiquitinated mitochondrial substrates (Sus scrofa)


name: nonanoate + 1-octadecanoyl-sn-glycero-3-phosphocholine + H(+) => 1-octadecanoyl-2-nonanoyl-sn-glycero-3-phosphocholine + H2O


name: MAPKAPK5 phosphorylates TP53 (Mus musculus)


name: minocycline(in) + H(+)(out) => minocycline(out) + H(+)(in)


name: BTN1A1 binds xanthine oxidoreductase (XDH) (Bos taurus)


name: an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + H2O => 3-methylcytosine + a 2'-deoxyribose 5'-monophosphate in double-stranded DNA + H(+)


name: Integrin alphaLbeta2 (LFA-1) binds F11R (JAM-A) (Mus musculus)


name: WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Sus scrofa)


name: SHC1 phosphorylation by phosphorylated EGFR (Rattus norvegicus)


name: VCP-NPL4-UFD1 AAA ATPase complex assembly


name: 2-hydroxyoctanoate + O2 = 2-oxooctanoate + H2O2


name: 1D-myo-inositol 4,5-bisphosphate + phosphate => 1D-myo-inositol 1,4,5-trisphosphate + H2O


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Bos taurus)


name: Caspase-8 activates BID by cleavage (Danio rerio)


name: 14-3-3-zeta binds Raf1 (Drosophila melanogaster)


name: ERGIC-to-Golgi vesicles bind dynein:dynactin  (Sus scrofa)


name: L-gulono-1,4-lactone + O2 => L-xylo-hex-3-ulonolactone + H2O2


name: questin + NADPH + O2 <=> demethylsulochrin + NADP(+)


name: Increased Cardiac Muscle Acetylcholine Activity


name: (S,S)-butane-2,3-diol + NAD(+) => (S)-acetoin + NADH + H(+)


name: stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential


name: Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases (Drosophila melanogaster)


name: Activated FGFR1 binds PLCG1 (Xenopus tropicalis)


name: The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)


name: octadecanamide + H2O = octadecanoate + NH4(+)


name: 3-oxosphinganine + NADPH + H(+) => sphinganine + NADP(+)


name: 1-decanoylglycerol + (9Z)-octadecenoyl-CoA <=> 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA


name: 11-cis-retinyl hexadecanoate + CoA => 11-cis-retinol + hexadecanoyl-CoA


name: Increased Autonomic Nervous System Brain Derived Neurotropic Activity


name: N(pros)-phospho-L-histidyl-[protein] + L-ascorbate(out) => L-ascorbate 6-phosphate(in) + L-histidyl-[protein]


name: 12-methyltridecanoyl-CoA + 2 malonyl-CoA + 2 H(+) = 4-hydroxy-6-(11-methyldodecyl)-pyran-2-one + 2 CO2 + 3 CoA


name: PIAS1 SUMOylates SATB1 with SUMO1 (Caenorhabditis elegans)


name: adenosylcob(III)inamide + ADP + phosphate + H(+) => (R)-1-aminopropan-2-ol + adenosylcob(III)yrate + ATP


name: 1-(ergostan-3beta-yl)-L-aspartate + H2O <=> ergosterol + L-aspartate + H(+)


name: D-serine transmembrane transporter activity


name: AHR:TCDD:2xHSP90AB1:AIP:PTGES3 dissociates (Sus scrofa)


name: UBE2I (UBC9), PIAS1 SUMOylate FOXL2 with SUMO1 (Saccharomyces cerevisiae)


name: long-chain fatty acid omega-hydroxylase activity


name: 1-(9Z-octadecenoyl)-2-(7Z,10Z,13Z,16Z,19Z-docosapentaenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O => 2-(7Z,10Z,13Z,16Z,19Z-docosapentaenoyl)-sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)


name: D-xylono-1,5-lactone + H2O2 => D-xylose + O2


name: CRHR2-2 binds CRH,UCN,UCN2,UCN3 (Homo sapiens)


name: Autocatalytic activation of proMMP2 (Homo sapiens)


name: KDM5A-D demethylate Me2K5-histone H3 (Mus musculus)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Sus scrofa)


name: AKR1A1 reduces D-glucuronate to L-gulonate (Mus musculus)


name: 5S-HpETE is reduced to 5S-HETE by GPX1/2/4 (Homo sapiens)


name: oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor


name: Class III (KCNA5) antiarrhythmics bind KCNA5 tetramers (Drosophila melanogaster)


name: a (2S,3R)-flavan-3-ol + 2 NADP(+) => an anthocyanidin with a 3-hydroxy group + 2 NADPH + 2 H(+)


name: SREBP1A,1C,2 translocates to the nucleus (Xenopus tropicalis)


name: DHRS7B reduces GO3P to HXDG3P (Mus musculus)


name: MPP cleaves targeting peptide (presequence) of inner membrane precursors (Homo sapiens)


name: KCNK dimers transport K+ from cytosol to extracellular region (Bos taurus)


name: a medium-chain fatty acid + CoA + H(+) => a medium-chain fatty acyl-CoA + H2O


name: (1S,2R,4S)-borneol + NAD(+) => (1S,4S)-camphor + NADH + H(+)


name: RAB:GTP recruits GBF1 to the Golgi membrane (Plasmodium falciparum)


name: Liganded G12/13-activating GPCR acts as a GEF for G12/13 (Sus scrofa)


name: octadecanoyl-CoA + FAD + H(+) = (2E)-octadecenoyl-CoA + FADH2


name: 17beta-hydroxy-5alpha-androstan-3-one + NADP(+) = 5alpha-androstan-3,17-dione + NADPH + H(+)


name: aldehydo-D-glucose 6-phosphate + L-lysyl-[protein] = N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein] + H2O


name: N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine + H(+) => adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine


name: UDP-alpha-D-xylose(in) + UDP-alpha-D-glucuronate(out) = UDP-alpha-D-xylose(out) + UDP-alpha-D-glucuronate(in)


name: 3-oxoisoapionate 4-phosphate + H2O <=> (2R)-3-phosphoglycerate + glycolate + H(+)


name: CES1 trimer.CES2 hydrolyse COCN to BEG (Canis familiaris)


name: Activated protein C cleaves Factor Va intermediate form for Factor Va (Gallus gallus)


name: PIP3 recruits PDK1 and AKT to the membrane (Dictyostelium discoideum)


name: (9Z)-tetradecenoyl-CoA + (R)-carnitine => O-(9Z)-tetradecenoyl-(R)-carnitine + CoA


name: Trans-autophosphorylation of ERBB2 heterodimers (Bos taurus)


name: HMGB1 release from cells (Xenopus tropicalis)


name: Ubiquitinated IkB is degraded (Sus scrofa)


name: iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide


name: (3Z)-hex-3-en-1-ol + acetyl-CoA = (3Z)-hex-3-en-1-yl acetate + CoA


name: RIOX1:Fe2+ hydroxylates a histidine residue of RPL8 (Dictyostelium discoideum)


name: N-acetyl-D-glucosamine 6-phosphate = aldehydo-N-acetyl-D-mannosamine 6-phosphate


name: Defective PAPSS2 does not transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)


name: a ganglioside GD1a + acetyl-CoA = a ganglioside Ac-O-7-GD1a + CoA


name: 4-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2


name: inosine(out) + Na(+)(out) = inosine(in) + Na(+)(in)


name: N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + H2O <=> 2-hydroxy-2-methylpropanoate + L-lysyl-[protein]


name: a ganglioside GQ1c (d18:1(4E)) + CMP + H(+) => a ganglioside GT1c (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate


name: STUB1 ubiquitinates RIPK1 at K571, K604, K627 (Canis familiaris)


name: enterobactin(in) + H(+)(out) = enterobactin(out) + H(+)(in)


name: 3beta,7alpha-dihydroxy-5alpha-androstan-17-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 3beta-hydroxy-5alpha-androstan-17-one + reduced [NADPH--hemoprotein reductase] + O2


name: N-(1H-1,3-benzodiazol-2-yl)carbamate + H(+) = 2-aminobenzimidazole + CO2


name: 2-phenylethylamine + pyruvate = 2-phenylacetaldehyde + L-alanine


name: OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Xenopus tropicalis)


name: Activated thrombin (factor IIa) cleaves F2R (PAR1), activating it (Sus scrofa)


name: NFE2L2 translocates from cytosol to nucleoplasm (Danio rerio)


name: dapdiamide C + ADP + phosphate + H(+) => N(3)-fumaramoyl-(S)-2,3-diaminopropanoate + L-leucine + ATP