preferred_name: holo-[lovastatin nonaketide synthase] + 9 malonyl-CoA + S-adenosyl-L-methionine + 11 NADPH + 19 H(+) <=> dihydromonacolin L-[lovastatin nonaketide synthase] + S-adenosyl-L-homocysteine + 9 CO2 + 11 NADP(+) + 9 CoA + 6 H2O