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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17609", "l": "HMG DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "HMG DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21068", "l": "SPARTIN", "d": [], "t": []}], "preferred_name": "SPARTIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21454:SF24", "l": "DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3", "d": [], "t": []}], "preferred_name": "DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24055:SF380", "l": "SERINE_THREONINE-PROTEIN KINASE NLK", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE NLK", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10196", "l": "SUGAR KINASE", "d": [], "t": []}], "preferred_name": "SUGAR KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF323", "l": "OLFACTORY RECEPTOR 2H1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 2H1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23403", "l": "TREHALASE", "d": [], "t": []}], "preferred_name": "TREHALASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21650", "l": "MEMBRALIN/KINETOCHORE PROTEIN NUF2", "d": [], "t": []}], "preferred_name": "MEMBRALIN/KINETOCHORE PROTEIN NUF2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3435", "l": "Cholinesterase family", "d": ["Cholinesterases may be classified as acetylcholinesterase (EC 3.1.1.7) and butyrylcholinesterase (EC 3.1.1.8) on the basis of differential specificity for acetylcholine and butyrylcholine hydrolysis. Several inhibitors have also been shown to be selective for one of the two enzymes. AChEs are primarily associated with nerve and muscle, typically with localization at synaptic contacts, while BChE is synthesized in the liver with substantial amounts appearing in serum."], "t": []}], "preferred_name": "Cholinesterase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3934", "l": "U2AF homology motif kinase family", "d": ["The U2AF Homology Motif Kinase 1 (UHMK1) is the only kinase that contains the U2AF homology motif, a common protein interaction domain among splicing factors. Through this motif, UHMK1 interacts with the splicing factors SF1 and SF3B1, known to participate in the 3' splice site recognition during the early steps of spliceosome assembly."], "t": []}], "preferred_name": "U2AF homology motif kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15001:SF8", "l": "BETA-DEFENSIN 121", "d": [], "t": []}], "preferred_name": "BETA-DEFENSIN 121", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11803:SF53", "l": "2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE", "d": [], "t": []}], "preferred_name": "2-IMINOBUTANOATE_2-IMINOPROPANOATE DEAMINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10269", "l": "GDNF RECEPTOR ALPHA", "d": [], "t": []}], "preferred_name": "GDNF RECEPTOR ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11259:SF4", "l": "RAS-RELATED GTP-BINDING PROTEIN B", "d": [], "t": []}], "preferred_name": "RAS-RELATED GTP-BINDING PROTEIN B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12893", "l": "GOLGI REASSEMBLY STACKING PROTEIN  GRASP", "d": [], "t": []}], "preferred_name": "GOLGI REASSEMBLY STACKING PROTEIN  GRASP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23031:SF5", "l": "RHOPHILIN-2-RELATED", "d": [], "t": []}], "preferred_name": "RHOPHILIN-2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46595:SF6", "l": "LARGE RIBOSOMAL SUBUNIT PROTEIN EL34", "d": [], "t": []}], "preferred_name": "LARGE RIBOSOMAL SUBUNIT PROTEIN EL34", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21642:SF4", "l": "CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN", "d": [], "t": []}], "preferred_name": "CEREBRAL CAVERNOUS MALFORMATIONS 2 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13169:SF0", "l": "UBIQUITIN-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "UBIQUITIN-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13398", "l": "GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2", "d": [], "t": []}], "preferred_name": "GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23268:SF31", "l": "T CELL RECEPTOR BETA VARIABLE 30", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA VARIABLE 30", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23268:SF40", "l": "T CELL RECEPTOR BETA VARIABLE 4-1", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA VARIABLE 4-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11630:SF75", "l": "MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "MINICHROMOSOME MAINTENANCE DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47992:SF150", "l": "PROTEIN PHOSPHATASE 1D", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44329:SF240", "l": "SERINE_THREONINE-PROTEIN KINASE B-RAF", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE B-RAF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1320", "l": "TTT complex", "d": ["In response to DNA damage, cells activate a complex signal transduction network called the DNA damage response (DDR).   TTI1 (Tel two-interacting protein 1) and TTI2 are highly conserved regulators of the DDR in mammals, protect cells from spontaneous DNA damage and are required for the establishment of the intra-S and G2/M checkpoints.    TTI1 and TTI2 exist in multiple complexes, including a 2-MDa complex with TEL2 (telomere maintenance 2), called the Triple T complex, and phosphoinositide-3-kinase-related protein kinases (PIKKs) such as ataxia telangiectasia-mutated (ATM). The components of the TTT complex are mutually dependent on each other, and act as critical regulators of PIKK abundance and checkpoint signaling."], "t": []}], "preferred_name": "TTT complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23036:SF108", "l": "GROWTH HORMONE RECEPTOR", "d": [], "t": []}], "preferred_name": "GROWTH HORMONE RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23039:SF3", "l": "NHS-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "NHS-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47536", "l": "C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A", "d": [], "t": []}], "preferred_name": "C-TYPE LECTIN DOMAIN FAMILY 5 MEMBER A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14389:SF14", "l": "SERINE PROTEASE FAM111A", "d": [], "t": []}], "preferred_name": "SERINE PROTEASE FAM111A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1927", "l": "Pepsinogens", "d": ["Pepsin is an endopeptidase that breaks down proteins into smaller peptides (that is, a protease). It is produced in the stomach and is one of the main digestive enzymes in the digestive systems of humans and many other animals, where it helps digest the proteins in food. Pepsin is an aspartic protease, using a catalytic aspartate in its active site.It is one of three principal proteases in the human digestive system, the other two being chymotrypsin and trypsin. During the process of digestion, these enzymes, each of which is specialized in severing links between particular types of amino acids, collaborate to break down dietary proteins into their components, i.e., peptides and amino acids, which can be readily absorbed by the small intestine. Pepsin is most efficient in cleaving peptide bonds between hydrophobic and preferably aromatic amino acids such as phenylalanine, tryptophan, and tyrosine. Pepsin's proenzyme, pepsinogen, is released by the chief cells in the stomach wall, and upon mixing with the hydrochloric acid of the gastric juice, pepsinogen activates to become pepsin."], "t": []}], "preferred_name": "Pepsinogens", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22168", "l": "TMEM26 PROTEIN", "d": [], "t": []}], "preferred_name": "TMEM26 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15380:SF2", "l": "CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 5", "d": [], "t": []}], "preferred_name": "CEROID-LIPOFUSCINOSIS NEURONAL PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16200:SF3", "l": "E3 UBIQUITIN-PROTEIN LIGASE ZNRF3", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE ZNRF3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46647", "l": "RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS", "d": [], "t": []}], "preferred_name": "RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48092:SF13", "l": "ANDROGEN RECEPTOR", "d": [], "t": []}], "preferred_name": "ANDROGEN RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22909", "l": "GOLGI INTEGRAL MEMBRANE PROTEIN 4", "d": [], "t": []}], "preferred_name": "GOLGI INTEGRAL MEMBRANE PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13303:SF0", "l": "PREFOLDIN SUBUNIT 2", "d": [], "t": []}], "preferred_name": "PREFOLDIN SUBUNIT 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24255:SF25", "l": "COMPLEMENT C1R SUBCOMPONENT", "d": [], "t": []}], "preferred_name": "COMPLEMENT C1R SUBCOMPONENT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15493:SF1", "l": "F-BOX ONLY PROTEIN 43", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 43", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24393:SF54", "l": "ZINC FINGER PROTEIN 580", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 580", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12002:SF74", "l": "CLAUDIN-15", "d": [], "t": []}], "preferred_name": "CLAUDIN-15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10682", "l": "POLY A  POLYMERASE", "d": [], "t": []}], "preferred_name": "POLY A  POLYMERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11675:SF68", "l": "N-ACETYLGALACTOSAMINYLTRANSFERASE 7", "d": [], "t": []}], "preferred_name": "N-ACETYLGALACTOSAMINYLTRANSFERASE 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21615:SF2", "l": "CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10687:SF6", "l": "SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 3", "d": [], "t": []}], "preferred_name": "SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43097", "l": "GLUTAMINE-TRNA LIGASE", "d": [], "t": []}], "preferred_name": "GLUTAMINE-TRNA LIGASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16093:SF4", "l": "INNATE IMMUNITY ACTIVATOR PROTEIN", "d": [], "t": []}], "preferred_name": "INNATE IMMUNITY ACTIVATOR PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11337:SF11", "l": "CD164 SIALOMUCIN-LIKE 2 PROTEIN", "d": [], "t": []}], "preferred_name": "CD164 SIALOMUCIN-LIKE 2 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42861:SF2", "l": "CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1", "d": [], "t": []}], "preferred_name": "CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2106", "l": "M49 metallopeptidase family", "d": [], "t": []}], "preferred_name": "M49 metallopeptidase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12902:SF7", "l": "ACTIN-BINDING PROTEIN WASF3", "d": [], "t": []}], "preferred_name": "ACTIN-BINDING PROTEIN WASF3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28557", "l": "PROTEIN SLX4IP", "d": [], "t": []}], "preferred_name": "PROTEIN SLX4IP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26454:SF8", "l": "OLFACTORY RECEPTOR 6C2", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 6C2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16290:SF5", "l": "MRNA-DECAPPING ENZYME 1B", "d": [], "t": []}], "preferred_name": "MRNA-DECAPPING ENZYME 1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:894", "l": "Astacins", "d": ["In molecular biology, the astacins are a family of metallopeptidases. These metallopeptidases belong to the MEROPS peptidase family M12, subfamily M12A (astacin family, clan MA(M)). The protein fold of the peptidase domain for members of this family resembles that of thermolysin, the type example for clan MA, and the predicted active site residues for members of this family and thermolysin occur in the motif HEXXH.   The astacin family of metalloendopeptidases (EC 3.4.24.21) encompasses a range of proteins found in hydra to humans, in mature and developmental systems. Their functions include activation of growth factors, degradation of polypeptides, and processing of extracellular proteins. The proteins are synthesised with N-terminal signal and pro-enzyme sequences, and many contain multiple domains C-terminal to the protease domain. They are either secreted from cells, or are associated with the plasma membrane.  The astacin molecule adopts a kidney shape, with a deep active-site cleft between its N- and C-terminal domains. The zinc ion, which lies at the bottom of the cleft, exhibits a unique penta-coordinated mode of binding, involving 3 histidine residues, a tyrosine and a water molecule (which is also bound to the carboxylate side chain of Glu93). The N-terminal domain comprises 2 alpha-helices and a 5-stranded beta-sheet. The overall topology of this domain is shared by the archetypal zinc-endopeptidase thermolysin. Astacin protease domains also share common features with serralysins, matrix metalloendopeptidases, and snake venom proteases; they cleave peptide bonds in polypeptides such as insulin B chain and bradykinin, and in proteins such as casein and gelatin; and they have arylamidase activity."], "t": []}], "preferred_name": "Astacins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43721:SF36", "l": "ELONGATION FACTOR TU, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ELONGATION FACTOR TU, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48018:SF189", "l": "OLFACTORY RECEPTOR 5T2", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 5T2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45623:SF20", "l": "CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7", "d": [], "t": []}], "preferred_name": "CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21040", "l": "BCDNA.GH04120", "d": [], "t": []}], "preferred_name": "BCDNA.GH04120", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15364:SF0", "l": "2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1", "d": [], "t": []}], "preferred_name": "2'-DEOXYNUCLEOSIDE 5'-PHOSPHATE N-HYDROLASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24136:SF14", "l": "ANKYRIN REPEAT AND SOCS BOX PROTEIN 11", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT AND SOCS BOX PROTEIN 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11492", "l": "NUCLEAR FACTOR I", "d": [], "t": []}], "preferred_name": "NUCLEAR FACTOR I", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:74", "l": "Zinc fingers CCHC-type", "d": ["This fold group is defined by two short β-strands connected by a turn (zinc knuckle) followed by a short helix or loop and resembles the classical Cys2His2 motif with a large portion of the helix and β-hairpin truncated."], "t": []}], "preferred_name": "Zinc fingers CCHC-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43655:SF9", "l": "AFG3-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "AFG3-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11845:SF13", "l": "5'-DEOXYNUCLEOTIDASE HDDC2", "d": [], "t": []}], "preferred_name": "5'-DEOXYNUCLEOTIDASE HDDC2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24409", "l": "ZINC FINGER PROTEIN 142", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 142", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24249:SF82", "l": "TRACE AMINE-ASSOCIATED RECEPTOR 3-RELATED", "d": [], "t": []}], "preferred_name": "TRACE AMINE-ASSOCIATED RECEPTOR 3-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12809:SF2", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17117:SF1", "l": "NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 3, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 3, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24270", "l": "LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED", "d": [], "t": []}], "preferred_name": "LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17416", "l": "SMALL MUSCULAR PROTEIN", "d": [], "t": []}], "preferred_name": "SMALL MUSCULAR PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11738:SF190", "l": "LEUKOCYTE-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR 2", "d": [], "t": []}], "preferred_name": "LEUKOCYTE-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24388:SF58", "l": "ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 4", "d": [], "t": []}], "preferred_name": "ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45906:SF4", "l": "ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1,3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1,3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48407:SF1", "l": "CRANIOFACIAL DEVELOPMENT PROTEIN 1", "d": [], "t": []}], "preferred_name": "CRANIOFACIAL DEVELOPMENT PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12669:SF5", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 3", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22446:SF3", "l": "M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "M-PHASE-SPECIFIC PLK1-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3662", "l": "Uridine-cytidine kinase family", "d": ["Uridine-cytidine kinase (UCK) is a pyrimidine ribonucleoside kinase that catalyzes the phosphorylation of uridine and cytidine to their monophosphate forms, UMP and CMP, respectively. This is the first step in the pyrimidine salvage pathway and is thought to be rate-limiting. There are three human genes that encode UCK activity [EC 2.7.1.48]."], "t": []}], "preferred_name": "Uridine-cytidine kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:461", "l": "Carboxylesterases", "d": ["In enzymology, a carboxylesterase or carboxylic-ester hydrolase ( EC 3.1.1.1 ) is an enzyme that catalyzes a chemical reaction of the form  a carboxylic ester + H 2O an alcohol + a carboxylate  Thus, the two substrates of this enzyme are carboxylic ester and H 2O, whereas its two products are alcohol and carboxylate."], "t": []}], "preferred_name": "Carboxylesterases", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10269:SF15", "l": "GDNF FAMILY RECEPTOR ALPHA-3", "d": [], "t": []}], "preferred_name": "GDNF FAMILY RECEPTOR ALPHA-3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14614:SF39", "l": "HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG", "d": [], "t": []}], "preferred_name": "HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3944", "l": "Pterin-4 alpha-carbinolamine dehydratases", "d": ["This group contains genes encoding pterin-4 alpha-carbinolamine dehydratase activity (EC 4.2.1.96). The PCBD1 and PCBD2 are paralogs and the encoded enzyme share 60% amino acid identity."], "t": []}], "preferred_name": "Pterin-4 alpha-carbinolamine dehydratases", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13183:SF0", "l": "AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1", "d": [], "t": []}], "preferred_name": "AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26450:SF175", "l": "OLFACTORY RECEPTOR 52E6", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 52E6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12396:SF5", "l": "METHYL-CPG-BINDING DOMAIN PROTEIN 2", "d": [], "t": []}], "preferred_name": "METHYL-CPG-BINDING DOMAIN PROTEIN 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24178:SF42", "l": "ANKYRIN REPEAT AND SOCS BOX PROTEIN 3", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT AND SOCS BOX PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47421", "l": "GS HOMEOBOX 2", "d": [], "t": []}], "preferred_name": "GS HOMEOBOX 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20383:SF10", "l": "RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 LIKE PROTEIN 1-RELATED", "d": [], "t": []}], "preferred_name": "RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 LIKE PROTEIN 1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45972", "l": "BTB_2 DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "BTB_2 DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:442", "l": "Alpha 1,4-glycosyltransferases", "d": [], "t": []}], "preferred_name": "Alpha 1,4-glycosyltransferases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13511", "l": "KXDL MOTIF-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "KXDL MOTIF-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15510:SF5", "l": "SPERM-ASSOCIATED ANTIGEN 8", "d": [], "t": []}], "preferred_name": "SPERM-ASSOCIATED ANTIGEN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24055:SF172", "l": "MITOGEN-ACTIVATED PROTEIN KINASE 9", "d": [], "t": []}], "preferred_name": "MITOGEN-ACTIVATED PROTEIN KINASE 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11573:SF6", "l": "RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT", "d": [], "t": []}], "preferred_name": "RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13222:SF1", "l": "RB1-INDUCIBLE COILED-COIL PROTEIN 1", "d": [], "t": []}], "preferred_name": "RB1-INDUCIBLE COILED-COIL PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16284:SF13", "l": "PROTEIN CDV3 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN CDV3 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15756:SF6", "l": "TRANSMEMBRANE PROTEIN 176A", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 176A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF0", "l": "OLFACTORY RECEPTOR 13D1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 13D1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31034", "l": "TRANSMEMBRANE PROTEIN 101", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 101", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11932:SF68", "l": "CULLIN-4A", "d": [], "t": []}], "preferred_name": "CULLIN-4A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23114:SF17", "l": "M7GPPPN-MRNA HYDROLASE", "d": [], "t": []}], "preferred_name": "M7GPPPN-MRNA HYDROLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21522", "l": "PROTON CHANNEL OTOP", "d": [], "t": []}], "preferred_name": "PROTON CHANNEL OTOP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:827", "l": "Extended synaptotagmins", "d": [], "t": []}], "preferred_name": "Extended synaptotagmins", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23430", "l": "HISTONE H2A", "d": [], "t": []}], "preferred_name": "HISTONE H2A", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24082:SF113", "l": "NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 1", "d": [], "t": []}], "preferred_name": "NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43539:SF23", "l": "FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46321", "l": "KIF1-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "KIF1-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10676:SF183", "l": "DYNEIN AXONEMAL HEAVY CHAIN 2", "d": [], "t": []}], "preferred_name": "DYNEIN AXONEMAL HEAVY CHAIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11584:SF332", "l": "MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5", "d": [], "t": []}], "preferred_name": "MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18861:SF1", "l": "ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1", "d": [], "t": []}], "preferred_name": "ELKS_RAB6-INTERACTING_CAST FAMILY MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15377:SF7", "l": "TRANSCRIPTION ELONGATION REGULATOR 1", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION ELONGATION REGULATOR 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10658:SF40", "l": "MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1", "d": [], "t": []}], "preferred_name": "MEMBRANE-ASSOCIATED PHOSPHATIDYLINOSITOL TRANSFER PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23061:SF12", "l": "DNA POLYMERASE ALPHA SUBUNIT B", "d": [], "t": []}], "preferred_name": "DNA POLYMERASE ALPHA SUBUNIT B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10501:SF84", "l": "U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B''", "d": [], "t": []}], "preferred_name": "U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B''", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21229:SF11", "l": "PROTEIN GPR108", "d": [], "t": []}], "preferred_name": "PROTEIN GPR108", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12484", "l": "B-LYMPHOCYTE ANTIGEN-RELATED", "d": [], "t": []}], "preferred_name": "B-LYMPHOCYTE ANTIGEN-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21091", "l": "METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED", "d": [], "t": []}], "preferred_name": "METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46600:SF11", "l": "THAP DOMAIN-CONTAINING PROTEIN 10", "d": [], "t": []}], "preferred_name": "THAP DOMAIN-CONTAINING PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37367", "l": "CHROMOSOME 4 OPEN READING FRAME 3", "d": [], "t": []}], "preferred_name": "CHROMOSOME 4 OPEN READING FRAME 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24261:SF12", "l": "HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "HEPATOCYTE GROWTH FACTOR-LIKE PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13800:SF9", "l": "TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 8", "d": [], "t": []}], "preferred_name": "TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY M MEMBER 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15493:SF8", "l": "F-BOX ONLY PROTEIN 5", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46389:SF4", "l": "CHROMOBOX PROTEIN HOMOLOG 6", "d": [], "t": []}], "preferred_name": "CHROMOBOX PROTEIN HOMOLOG 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13147:SF5", "l": "FOUR-JOINTED BOX PROTEIN 1", "d": [], "t": []}], "preferred_name": "FOUR-JOINTED BOX PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22883:SF270", "l": "PALMITOYLTRANSFERASE ZDHHC15", "d": [], "t": []}], "preferred_name": "PALMITOYLTRANSFERASE ZDHHC15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12411", "l": "CYSTEINE PROTEASE FAMILY C1-RELATED", "d": [], "t": []}], "preferred_name": "CYSTEINE PROTEASE FAMILY C1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21222:SF1", "l": "MIT DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "MIT DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24241:SF1", "l": "G-PROTEIN COUPLED RECEPTOR 22", "d": [], "t": []}], "preferred_name": "G-PROTEIN COUPLED RECEPTOR 22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16886:SF0", "l": "HYPOXIA-INDUCIBLE LIPID DROPLET-ASSOCIATED PROTEIN", "d": [], "t": []}], "preferred_name": "HYPOXIA-INDUCIBLE LIPID DROPLET-ASSOCIATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF34", "l": "CORTICOSTEROID-BINDING GLOBULIN", "d": [], "t": []}], "preferred_name": "CORTICOSTEROID-BINDING GLOBULIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:370", "l": "T cell receptors", "d": ["T cell receptors (TR) are antigen receptors of the T cells of the adaptive immune response, acquired by jawed vertebrates (or gnathostomata) more than 450 million years ago and found in all extant jawed vertebrate species from fishes to humans. TR are anchored in the membrane of a T cell as part of the signaling T cell receptor (TcR = TR+CD3). TR alpha/beta recognize processed antigens, which are presented as peptides by the highly polymorphic major histocompatibility (MH, in humans HLA for human leukocyte antigens) proteins, whereas TR gamma/delta recognize nonpeptidic antigens. TR are made of two chains, alpha and beta, or gamma and delta, encoded by genes located in four major loci: the TR alpha (TRA) at 14q11.2, TR beta (TRB) at 7q34, TR gamma (TRG) at 7p14 and TR delta (TRD) at 14q11.2. Genes outside of these major loci are orphons. There are four TR gene types, variable (V), diversity (D) (for TRB and TRD), joining (J) and constant (C) genes which contribute to the TR chain synthesis. The variable domain at the N-terminal end of each TR chain results from a V-(D)-J rearrangement whereas the remaining of the chain, or constant region, is encoded by a C gene. The combinatorial and junctional diversity creates a huge potential diversity of 1012 specific TR per individual, the limiting factor being only the number of T cells that an organism is genetically programmed to produce."], "t": []}], "preferred_name": "T cell receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46568", "l": "ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL", "d": [], "t": []}], "preferred_name": "ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46735:SF7", "l": "SORCIN", "d": [], "t": []}], "preferred_name": "SORCIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24026:SF32", "l": "CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 2", "d": [], "t": []}], "preferred_name": "CADHERIN EGF LAG SEVEN-PASS G-TYPE RECEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11592:SF127", "l": "EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE", "d": [], "t": []}], "preferred_name": "EPIDIDYMAL SECRETORY GLUTATHIONE PEROXIDASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24365:SF17", "l": "TOLL-LIKE RECEPTOR 2", "d": [], "t": []}], "preferred_name": "TOLL-LIKE RECEPTOR 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23064:SF29", "l": "PARVALBUMIN-LIKE EF-HAND-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "PARVALBUMIN-LIKE EF-HAND-CONTAINING PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF254", "l": "PROTOCADHERIN-11 X-LINKED-RELATED", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN-11 X-LINKED-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16515:SF63", "l": "PR DOMAIN ZINC FINGER PROTEIN 1", "d": [], "t": []}], "preferred_name": "PR DOMAIN ZINC FINGER PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12127:SF4", "l": "MUCOLIPIN-2", "d": [], "t": []}], "preferred_name": "MUCOLIPIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23277", "l": "NECTIN-RELATED", "d": [], "t": []}], "preferred_name": "NECTIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13627:SF31", "l": "RIBITOL 5-PHOSPHATE TRANSFERASE FKRP", "d": [], "t": []}], "preferred_name": "RIBITOL 5-PHOSPHATE TRANSFERASE FKRP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10405", "l": "SPINDLIN", "d": [], "t": []}], "preferred_name": "SPINDLIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12101:SF18", "l": "POPEYE DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "POPEYE DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46763:SF1", "l": "DYNEIN REGULATORY COMPLEX PROTEIN 8", "d": [], "t": []}], "preferred_name": "DYNEIN REGULATORY COMPLEX PROTEIN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11606:SF15", "l": "GLUTAMATE DEHYDROGENASE 2, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "GLUTAMATE DEHYDROGENASE 2, MITOCHONDRIAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24381:SF74", "l": "ZINC FINGER PROTEIN 69 HOMOLOG", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 69 HOMOLOG", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11509", "l": "GLYCOPROTEIN HORMONE ALPHA CHAIN", "d": [], "t": []}], "preferred_name": "GLYCOPROTEIN HORMONE ALPHA CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46360", "l": "DISKS LARGE HOMOLOG 5", "d": [], "t": []}], "preferred_name": "DISKS LARGE HOMOLOG 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28671:SF3", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 169", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 169", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46299:SF2", "l": "VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2", "d": [], "t": []}], "preferred_name": "VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5B2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:762", "l": "Sulfotransferases, cytosolic", "d": [], "t": []}], "preferred_name": "Sulfotransferases, cytosolic", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10545:SF63", "l": "SPERMIDINE_SPERMINE N(1)-ACETYLTRANSFERASE-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "SPERMIDINE_SPERMINE N(1)-ACETYLTRANSFERASE-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15937:SF3", "l": "TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44145:SF3", "l": "DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19854", "l": "TRANSDUCIN BETA-LIKE 3", "d": [], "t": []}], "preferred_name": "TRANSDUCIN BETA-LIKE 3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35970:SF1", "l": "SODIUM CHANNEL AND CLATHRIN LINKER 1", "d": [], "t": []}], "preferred_name": "SODIUM CHANNEL AND CLATHRIN LINKER 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21452", "l": "EXPORTIN-6", "d": [], "t": []}], "preferred_name": "EXPORTIN-6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39234", "l": "TRANSMEMBRANE PROTEIN 210", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 210", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11009:SF31", "l": "RHOMBOID DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "RHOMBOID DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10878:SF6", "l": "SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3", "d": [], "t": []}], "preferred_name": "SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10099:SF1", "l": "PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE", "d": [], "t": []}], "preferred_name": "PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16483:SF0", "l": "BRICHOS DOMAIN-CONTAINING PROTEIN 5", "d": [], "t": []}], "preferred_name": "BRICHOS DOMAIN-CONTAINING PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18887:SF2", "l": "GOLGIN SUBFAMILY B MEMBER 1", "d": [], "t": []}], "preferred_name": "GOLGIN SUBFAMILY B MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF247", "l": "PROTOCADHERIN-1", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10527:SF22", "l": "IMPORTIN-5", "d": [], "t": []}], "preferred_name": "IMPORTIN-5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15683:SF5", "l": "SAFB-LIKE TRANSCRIPTION MODULATOR", "d": [], "t": []}], "preferred_name": "SAFB-LIKE TRANSCRIPTION MODULATOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11533", "l": "PROTEASE M1 ZINC METALLOPROTEASE", "d": [], "t": []}], "preferred_name": "PROTEASE M1 ZINC METALLOPROTEASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24264", "l": "TRYPSIN-RELATED", "d": [], "t": []}], "preferred_name": "TRYPSIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48021:SF59", "l": "SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 6", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23113:SF167", "l": "RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1", "d": [], "t": []}], "preferred_name": "RAS-SPECIFIC GUANINE NUCLEOTIDE-RELEASING FACTOR RALGPS1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33505", "l": "ZGC:162634", "d": [], "t": []}], "preferred_name": "ZGC:162634", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22550:SF5", "l": "LEUCINE ZIPPER PROTEIN 4", "d": [], "t": []}], "preferred_name": "LEUCINE ZIPPER PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43648:SF1", "l": "ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "ELECTRON TRANSFER FLAVOPROTEIN BETA SUBUNIT LYSINE METHYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46490", "l": "C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED", "d": [], "t": []}], "preferred_name": "C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10697:SF1", "l": "MAMMALIAN EPENDYMIN-RELATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "MAMMALIAN EPENDYMIN-RELATED PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11988:SF28", "l": "HEPATIC LEUKEMIA FACTOR", "d": [], "t": []}], "preferred_name": "HEPATIC LEUKEMIA FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:145", "l": "Zinc fingers LYAR C2HC-type", "d": ["LYAR, which is known to be expressed abundantly in the testis, encodes a nucleolar protein that contain a LYAR-type C2HC zinc finger motif and three nuclear localization signals."], "t": []}], "preferred_name": "Zinc fingers LYAR C2HC-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13677", "l": "LD41638P", "d": [], "t": []}], "preferred_name": "LD41638P", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11034:SF17", "l": "PROTEIN NDRG2", "d": [], "t": []}], "preferred_name": "PROTEIN NDRG2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11630:SF42", "l": "DNA REPLICATION LICENSING FACTOR MCM5", "d": [], "t": []}], "preferred_name": "DNA REPLICATION LICENSING FACTOR MCM5", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23127:SF0", "l": "H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1", "d": [], "t": []}], "preferred_name": "H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14076:SF2", "l": "RECEPTOR ACTIVITY-MODIFYING PROTEIN 3", "d": [], "t": []}], "preferred_name": "RECEPTOR ACTIVITY-MODIFYING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13943:SF36", "l": "PHOSPHOLIPASE A AND ACYLTRANSFERASE 4", "d": [], "t": []}], "preferred_name": "PHOSPHOLIPASE A AND ACYLTRANSFERASE 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11214:SF153", "l": "UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1", "d": [], "t": []}], "preferred_name": "UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21255:SF27", "l": "DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2", "d": [], "t": []}], "preferred_name": "DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23188", "l": "RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG", "d": [], "t": []}], "preferred_name": "RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46562", "l": "SERINE/THREONINE-KINASE ULK4-LIKE PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "SERINE/THREONINE-KINASE ULK4-LIKE PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24350", "l": "SERINE/THREONINE-PROTEIN KINASE IAL-RELATED", "d": [], "t": []}], "preferred_name": "SERINE/THREONINE-PROTEIN KINASE IAL-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF320", "l": "SERPIN B3", "d": [], "t": []}], "preferred_name": "SERPIN B3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14360:SF11", "l": "MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20859:SF55", "l": "INTERFERON LAMBDA RECEPTOR 1", "d": [], "t": []}], "preferred_name": "INTERFERON LAMBDA RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31075:SF3", "l": "CENTROSOMAL PROTEIN OF 85 KDA", "d": [], "t": []}], "preferred_name": "CENTROSOMAL PROTEIN OF 85 KDA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11738:SF186", "l": "OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR", "d": [], "t": []}], "preferred_name": "OSTEOCLAST-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23287:SF16", "l": "TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10652:SF2", "l": "ADENYLYL CYCLASE-ASSOCIATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "ADENYLYL CYCLASE-ASSOCIATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16592:SF8", "l": "ASTROTACTIN-1", "d": [], "t": []}], "preferred_name": "ASTROTACTIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12360:SF1", "l": "NF-X1-TYPE ZINC FINGER PROTEIN NFXL1", "d": [], "t": []}], "preferred_name": "NF-X1-TYPE ZINC FINGER PROTEIN NFXL1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22420", "l": "PROTEIN FAM81A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM81A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15035:SF9", "l": "CORTICOLIBERIN", "d": [], "t": []}], "preferred_name": "CORTICOLIBERIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23235:SF56", "l": "KRUEPPEL-LIKE FACTOR 12", "d": [], "t": []}], "preferred_name": "KRUEPPEL-LIKE FACTOR 12", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35355:SF2", "l": "PROTEIN FAM229B", "d": [], "t": []}], "preferred_name": "PROTEIN FAM229B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48036:SF3", "l": "RNA-BINDING PROTEIN 23-RELATED", "d": [], "t": []}], "preferred_name": "RNA-BINDING PROTEIN 23-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10182", "l": "CALCIUM-BINDING PROTEIN 39-RELATED", "d": [], "t": []}], "preferred_name": "CALCIUM-BINDING PROTEIN 39-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21297:SF0", "l": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4", "d": [], "t": []}], "preferred_name": "DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10199:SF89", "l": "THROMBOSPONDIN-3", "d": [], "t": []}], "preferred_name": "THROMBOSPONDIN-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1282", "l": "Membrane associated progesterone receptor family", "d": [], "t": []}], "preferred_name": "Membrane associated progesterone receptor family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1639", "l": "Complement system regulators and receptors", "d": [], "t": []}], "preferred_name": "Complement system regulators and receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF20", "l": "ALPHA-2-ANTIPLASMIN", "d": [], "t": []}], "preferred_name": "ALPHA-2-ANTIPLASMIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14205", "l": "WD-REPEAT PROTEIN", "d": [], "t": []}], "preferred_name": "WD-REPEAT PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11933", "l": "TRNA  5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "TRNA  5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19139:SF39", "l": "LENS FIBER MAJOR INTRINSIC PROTEIN", "d": [], "t": []}], "preferred_name": "LENS FIBER MAJOR INTRINSIC PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1215", "l": "Transmembrane BAX inhibitor motif containing", "d": [], "t": []}], "preferred_name": "Transmembrane BAX inhibitor motif containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23503:SF22", "l": "SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 11", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12482:SF3", "l": "PROTEIN FAM135B", "d": [], "t": []}], "preferred_name": "PROTEIN FAM135B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46035", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 4", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11071:SF490", "l": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A", "d": [], "t": []}], "preferred_name": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:249", "l": "Transient receptor potential cation channels", "d": ["Transient receptor potential channels (TRP channels) are a group of ion channels located mostly on the plasma membrane of numerous human and animal cell types. There are about 28 TRP channels that share some structural similarity to each other. These are grouped into two broad groups: Group 1 includes TRPC ( 'C' for canonical), TRPV ('V' for vanilloid), TRPM ('M' for melastatin), TRPN, and TRPA. In group 2, there are TRPP ('P' for polycystic) and TRPML ('ML' for mucolipin). Many of these channels mediate a variety of sensations like the sensations of pain, hotness, warmth or coldness, different kinds of tastes, pressure, and vision. In the body, some TRP channels are thought to behave like microscopic thermometers and used in animals to sense hot or cold. Some TRP channels are activated by molecules found in spices like garlic ( allicin ), chilli pepper ( capsaicin ), wasabi ( allyl isothiocyanate ); others are activated by menthol, camphor, peppermint, and cooling agents; yet others are activated by molecules found in cannabis (i.e., THC, CBD and CBN ). Some act as sensors of osmotic pressure, volume, stretch, and vibration.  These ion channels are relatively non-selectively permeable to cations, including sodium, calcium and magnesium. TRP channels were initially discovered in trp -mutant strain of the fruit fly Drosophila. Later, TRP channels were found in vertebrates where they are ubiquitously expressed in many cell types and tissues. Most TRP channels are composed of 6 membrane -spanning helices with intracellular N- and C-termini. Mammalian TRP channels are activated and regulated by a wide variety of stimuli and are expressed throughout the body."], "t": []}], "preferred_name": "Transient receptor potential cation channels", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43818:SF8", "l": "GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1342", "l": "Death inducing signaling complex", "d": ["The death-inducing signaling complex or DISC is a multi-protein complex formed by members of the 'death receptor' family of apoptosis -inducing cellular receptors. A typical example is FasR, which forms the DISC upon trimerization as a result of its ligand ( FasL ) binding. The DISC is composed of the death receptor, FADD, and caspase 8. It transduces a downstream signal cascade resulting in apoptosis.  The Fas ligands, or cytotoxicity-dependent APO-1-associated proteins, physically associate with APO-1 (also known as the Fas receptor, or CD95), a tumor necrosis factor containing a functional death domain. This association leads to the formation of the DISC, thereby inducing apoptosis. The entire process is initiated when the cell registers the presence of CD95L, the cognate ligand for APO-1. Upon binding, the CAP proteins and procaspase-8 (composed of FLICE, MACH, and Mch5) bind to CD95 through death domain and death effector domain interactions. Procaspase-8 activation is thought to occur through a dimerization process with other procaspase-8 molecules, known as an induced proximity model.  The CAP proteins associate only with the oligomerized version of APO-1 when forming the complex. The CAP1 are CAP2 proteins are also known as FADD/MORT1, an adaptor molecule with a death domain. CAP4 is also called FLICE, a cysteine protease with two death effector domains. CAP3 is the prodomain of FLICE generated during proteolytic activation. Once the DISC assembles, it allows APO-1 signaling to occur, which triggers cell death. In order to do this, downstream targets such as FLICE must be activated. In its inactive state, FLICE's two death domains are thought to bind together and prevent its activation. Once APO-1 aggregates within the cytosol, it recruits FADD, CAP3, and FLICE to the receptor, where FLICE is modified into several active subunits, which have the ability to cleave a variety of substrates. This proteolytic activity then results in a cascade of caspase activation, and ultimately cell death. This apoptotic activity is critical for tissue homeostasis and immune function.  APO-1-mediated apoptosis can be inhibited by a variety of factors, including the viral caspase inhibitors CrmA and p35, as well as viral FLICE-inhibitory proteins known as v-FLIPs. When in the presence of APO-1, v-FLIPs preferentially bind and prevent procaspase-8 from being recruited; as such, apoptosis is stalled. Interestingly, humans have a homolog for v-FLIP known as c-FLIP, which occurs in two endogenous forms (c-FLIPL (long) and c-FLIPS (short)). These are similar in structure to procaspase-8, but lack the amino acids necessary for caspase-8 catalytic activity. It is thought that c-FLIP may be involved in modulating the immune system, as c-FLIPS is upregulated upon stimulation of the T cell receptor. Furthermore, as high expression of FLIP is known to promote tumor growth, these inhibitor molecules play a role in cancer proliferation.  The DISC has been implicated as a possible drug development target for various cancers, including leukemia, glioma, and colon cancer. In glioma cells, the effects of TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) have been shown to induce DISC-mediated apoptosis. Specifically, TRAIL works by activating two death receptors, DR4 and DR5; these bind to FADD, which then interacts with caspase-8 to assemble the DISC. Tumor cells show varying sensitivity to TRAIL modulated apoptosis, depending on the presence of the antiapoptotic FLIP proteins. Additionally, studies in leukemia have indicated that the histone deacetylase inhibitor LAQ824 increases apoptosis by decreasing the expression levels of the c-FLIPs. As such, these inhibitors are promising targets for anti-cancer therapy."], "t": []}], "preferred_name": "Death inducing signaling complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45976", "l": "ARMADILLO SEGMENT POLARITY PROTEIN", "d": [], "t": []}], "preferred_name": "ARMADILLO SEGMENT POLARITY PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1516", "l": "Spliceosomal P complex", "d": ["The spliceosomal P complex is a large stable splicing complex that forms after the spliceosomal <a href='https://www.genenames.org/data/genegroup/#!/group/1510'>C complex</a> but before mRNA release."], "t": []}], "preferred_name": "Spliceosomal P complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23123", "l": "PHD/F-BOX CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "PHD/F-BOX CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR38649:SF1", "l": "SPERMATOGENESIS-ASSOCIATED PROTEIN 33", "d": [], "t": []}], "preferred_name": "SPERMATOGENESIS-ASSOCIATED PROTEIN 33", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14233:SF12", "l": "SOLUTE CARRIER FAMILY 35 MEMBER F2", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 35 MEMBER F2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22990", "l": "F-BOX ONLY PROTEIN", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1759", "l": "MicroRNA MIR153 family", "d": [], "t": []}], "preferred_name": "MicroRNA MIR153 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10514:SF24", "l": "ANGIOTENSIN-CONVERTING ENZYME 2", "d": [], "t": []}], "preferred_name": "ANGIOTENSIN-CONVERTING ENZYME 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46269:SF4", "l": "OPTICIN", "d": [], "t": []}], "preferred_name": "OPTICIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37344:SF1", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 5", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23105:SF31", "l": "RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14102:SF12", "l": "CDNA SEQUENCE BC034090", "d": [], "t": []}], "preferred_name": "CDNA SEQUENCE BC034090", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10640", "l": "METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE", "d": [], "t": []}], "preferred_name": "METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24248:SF130", "l": "ALPHA-2B ADRENERGIC RECEPTOR", "d": [], "t": []}], "preferred_name": "ALPHA-2B ADRENERGIC RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11822", "l": "NADP-SPECIFIC ISOCITRATE DEHYDROGENASE", "d": [], "t": []}], "preferred_name": "NADP-SPECIFIC ISOCITRATE DEHYDROGENASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19848:SF0", "l": "NOTCHLESS PROTEIN HOMOLOG 1", "d": [], "t": []}], "preferred_name": "NOTCHLESS PROTEIN HOMOLOG 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10554:SF3", "l": "GAMMA-2-SYNTROPHIN", "d": [], "t": []}], "preferred_name": "GAMMA-2-SYNTROPHIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10627:SF70", "l": "ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31383", "l": "OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1", "d": [], "t": []}], "preferred_name": "OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22192:SF16", "l": "SPERIOLIN", "d": [], "t": []}], "preferred_name": "SPERIOLIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28605", "l": "CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)", "d": [], "t": []}], "preferred_name": "CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11202:SF19", "l": "SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46389", "l": "POLYCOMB GROUP PROTEIN PC", "d": [], "t": []}], "preferred_name": "POLYCOMB GROUP PROTEIN PC", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12213", "l": "CORRINOID ADENOSYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "CORRINOID ADENOSYLTRANSFERASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16983:SF1", "l": "PROSTATE STEM CELL ANTIGEN", "d": [], "t": []}], "preferred_name": "PROSTATE STEM CELL ANTIGEN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43078", "l": "UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED", "d": [], "t": []}], "preferred_name": "UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2025", "l": "3-hydroxyacyl-CoA dehydratase family", "d": [], "t": []}], "preferred_name": "3-hydroxyacyl-CoA dehydratase family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48034:SF17", "l": "RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER A1-RELATED", "d": [], "t": []}], "preferred_name": "RNA-BINDING MOTIF PROTEIN, Y CHROMOSOME, FAMILY 1 MEMBER A1-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15961:SF3", "l": "PROTEIN EURL HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN EURL HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13822:SF7", "l": "ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23254:SF15", "l": "POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1", "d": [], "t": []}], "preferred_name": "POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21409", "l": "HEMATOPOIETIC CELL SIGNAL TRANSDUCER", "d": [], "t": []}], "preferred_name": "HEMATOPOIETIC CELL SIGNAL TRANSDUCER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14060:SF2", "l": "T-CELL LEUKEMIA_LYMPHOMA PROTEIN 1B", "d": [], "t": []}], "preferred_name": "T-CELL LEUKEMIA_LYMPHOMA PROTEIN 1B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10217:SF530", "l": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1", "d": [], "t": []}], "preferred_name": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10302", "l": "SINGLE-STRANDED DNA-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "SINGLE-STRANDED DNA-BINDING PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13129:SF4", "l": "DDB1- AND CUL4-ASSOCIATED FACTOR 1", "d": [], "t": []}], "preferred_name": "DDB1- AND CUL4-ASSOCIATED FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35153:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 154", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 154", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20920:SF2", "l": "SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13768:SF12", "l": "BETA-SOLUBLE NSF ATTACHMENT PROTEIN", "d": [], "t": []}], "preferred_name": "BETA-SOLUBLE NSF ATTACHMENT PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45725:SF16", "l": "DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1", "d": [], "t": []}], "preferred_name": "DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14003:SF10", "l": "TRANSCRIPTIONAL REPRESSOR PROTEIN YY1", "d": [], "t": []}], "preferred_name": "TRANSCRIPTIONAL REPRESSOR PROTEIN YY1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24384:SF102", "l": "ZINC FINGER PROTEIN 141", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 141", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14741", "l": "S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED", "d": [], "t": []}], "preferred_name": "S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23157", "l": "GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43948:SF6", "l": "DNAJ HOMOLOG SUBFAMILY B MEMBER 6", "d": [], "t": []}], "preferred_name": "DNAJ HOMOLOG SUBFAMILY B MEMBER 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23359:SF59", "l": "ADENYLATE KINASE ISOENZYME 1", "d": [], "t": []}], "preferred_name": "ADENYLATE KINASE ISOENZYME 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22691:SF1", "l": "CENTROSOMAL PROTEIN CCDC61", "d": [], "t": []}], "preferred_name": "CENTROSOMAL PROTEIN CCDC61", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10489:SF671", "l": "C-X-C CHEMOKINE RECEPTOR TYPE 3", "d": [], "t": []}], "preferred_name": "C-X-C CHEMOKINE RECEPTOR TYPE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42884:SF7", "l": "PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5", "d": [], "t": []}], "preferred_name": "PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46330", "l": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B", "d": [], "t": []}], "preferred_name": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 10B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43416:SF18", "l": "DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12266", "l": "NA+/CA2+ K+ INDEPENDENT EXCHANGER", "d": [], "t": []}], "preferred_name": "NA+/CA2+ K+ INDEPENDENT EXCHANGER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31994", "l": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12112:SF11", "l": "PROTEIN PRUNE HOMOLOG 2", "d": [], "t": []}], "preferred_name": "PROTEIN PRUNE HOMOLOG 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13162", "l": "CCR4-NOT TRANSCRIPTION COMPLEX", "d": [], "t": []}], "preferred_name": "CCR4-NOT TRANSCRIPTION COMPLEX", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36689:SF1", "l": "POU CLASS 2 HOMEOBOX ASSOCIATING FACTOR 3", "d": [], "t": []}], "preferred_name": "POU CLASS 2 HOMEOBOX ASSOCIATING FACTOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44186:SF1", "l": "BARDET-BIEDL SYNDROME 4 PROTEIN", "d": [], "t": []}], "preferred_name": "BARDET-BIEDL SYNDROME 4 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19375:SF553", "l": "HEAT SHOCK 70 KDA PROTEIN 6-RELATED", "d": [], "t": []}], "preferred_name": "HEAT SHOCK 70 KDA PROTEIN 6-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46451", "l": "RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24340:SF72", "l": "HOMEOBOX PROTEIN NKX-2.6", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN NKX-2.6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:519", "l": "NKL subclass homeoboxes and pseudogenes", "d": [], "t": []}], "preferred_name": "NKL subclass homeoboxes and pseudogenes", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10908", "l": "SEROTONIN N-ACETYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "SEROTONIN N-ACETYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:757", "l": "SRY-box transcription factors", "d": ["SOX genes encode a family of transcription factors that bind to the minor groove in DNA, and belong to a super-family of genes characterized by a homologous sequence called the HMG-box (for high mobility group ). This HMG box is a DNA binding domain that is highly conserved throughout eukaryotic species. Homologues have been identified in insects, nematodes, amphibians, reptiles, birds and a range of mammals. However, HMG boxes can be very diverse in nature, with only a few amino acids being conserved between species.  Sox genes are defined as containing the HMG box of a gene involved in sex determination called SRY, which resides on the Y-chromosome (Sox stands for Sry-related HMG box). There are 20 SOX genes present in humans and mice, and 8 present in Drosophila. Almost all Sox genes show at least 50% amino acid similarity with the HMG box in Sry. The family is divided into subgroups according to homology within the HMG domain and other structural motifs, as well as according to functional assays."], "t": []}], "preferred_name": "SRY-box transcription factors", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13976:SF60", "l": "HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H", "d": [], "t": []}], "preferred_name": "HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16291", "l": "NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3", "d": [], "t": []}], "preferred_name": "NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3531", "l": "Epsin family", "d": ["Epsins are a family of endocytic adaptor proteins composed of 3 paralogs: EPN1, EPN2 and EPN3. Epsins are known to be involved in the first steps of endocytosis in particular there is evidence that they have a specific role in cargo selection and coat assembly. From a structural perspective, epsins share a similar protein structure. They possess an epsin N-terminal homology (ENTH) domain necessary to bind PtdIns(4,5)P2 at the PM, two or three ubiquitin interacting motifs (UIMs) known to bind to ubiquitinated cargoes, and the aspartate-proline-tryptophan (DPW) and asparagine-proline-phenylalanine (NPF) motifs that interact with the clathrin machinery. Since the protein structure of the three isoforms is similar, redundant functions have been observed in endocytosis, regulation of the actin cytoskeleton during clathrin-mediated endocytosis, and development."], "t": []}], "preferred_name": "Epsin family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11188", "l": "ARRESTIN DOMAIN CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "ARRESTIN DOMAIN CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46876:SF1", "l": "LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11", "d": [], "t": []}], "preferred_name": "LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10423", "l": "INSULIN-LIKE 3", "d": [], "t": []}], "preferred_name": "INSULIN-LIKE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12138:SF152", "l": "C2H2-TYPE DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "C2H2-TYPE DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23099:SF0", "l": "GERM CELL NUCLEAR ACIDIC PROTEIN", "d": [], "t": []}], "preferred_name": "GERM CELL NUCLEAR ACIDIC PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22765:SF30", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF128", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF128", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11767:SF52", "l": "G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4", "d": [], "t": []}], "preferred_name": "G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46131:SF5", "l": "SOLUTE CARRIER FAMILY 25 MEMBER 53", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 25 MEMBER 53", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16431", "l": "NEUROGENIC PROTEIN MASTERMIND", "d": [], "t": []}], "preferred_name": "NEUROGENIC PROTEIN MASTERMIND", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15478:SF5", "l": "PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 3", "d": [], "t": []}], "preferred_name": "PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19325:SF545", "l": "COMPLEMENT RECEPTOR TYPE 1", "d": [], "t": []}], "preferred_name": "COMPLEMENT RECEPTOR TYPE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31943:SF17", "l": "INTERFERON LAMBDA-4", "d": [], "t": []}], "preferred_name": "INTERFERON LAMBDA-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46059:SF3", "l": "BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2", "d": [], "t": []}], "preferred_name": "BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15706:SF10", "l": "NADPH OXIDASE ORGANIZER 1", "d": [], "t": []}], "preferred_name": "NADPH OXIDASE ORGANIZER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11267:SF116", "l": "T-BOX TRANSCRIPTION FACTOR TBX22", "d": [], "t": []}], "preferred_name": "T-BOX TRANSCRIPTION FACTOR TBX22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24381:SF344", "l": "ZINC FINGER PROTEIN 79", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 79", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:73", "l": "Zinc fingers CCCH-type", "d": ["Zinc finger proteins are generally thought of as DNA-binding transcription factors. However, certain classes of zinc finger proteins, such as CCCH zinc finger proteins, often function as RNA-binding proteins and regulate RNA metabolism. CCCH zinc finger proteins are characterized by one or more CCCH zinc finger domains containing three cysteines and a histidine. Although the functions of most CCCH zinc finger proteins remain obscure, emerging evidence suggests that some CCCH zinc finger proteins are involved in a broad range of biological processes that are associated with immune responses, including cytokine production, immune cell activation, immune homeostasis and antiviral innate immunity, as well as in regulation of cell differentiation and cancer cell growth."], "t": []}], "preferred_name": "Zinc fingers CCCH-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11895:SF153", "l": "GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46789", "l": "FORKHEAD BOX PROTEIN R1", "d": [], "t": []}], "preferred_name": "FORKHEAD BOX PROTEIN R1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21727:SF0", "l": "MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47134", "l": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A", "d": [], "t": []}], "preferred_name": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:928", "l": "VPS9 domain containing", "d": [], "t": []}], "preferred_name": "VPS9 domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10129:SF25", "l": "TRANSCRIPTION FACTOR MAFF", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR MAFF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11038", "l": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23239:SF105", "l": "KERATIN, TYPE I CYTOSKELETAL 16", "d": [], "t": []}], "preferred_name": "KERATIN, TYPE I CYTOSKELETAL 16", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12431", "l": "SORTING NEXIN 17 AND 27", "d": [], "t": []}], "preferred_name": "SORTING NEXIN 17 AND 27", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47656:SF1", "l": "HOMEOBOX PROTEIN MIXL1", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN MIXL1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2125", "l": "Zinc fingers PCLO-type", "d": ["Piccolo zinc fingers were found to interact with the dual prenylated rab3A and VAMP2/Synaptobrevin II receptor PRA1. There are eight conserved cysteines in Piccolo-type zinc fingers, suggesting that they coordinate two zinc ligands."], "t": []}], "preferred_name": "Zinc fingers PCLO-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13218:SF18", "l": "TATA-BOX-BINDING PROTEIN-ASSOCIATED FACTOR 11-LIKE PROTEIN 10-RELATED", "d": [], "t": []}], "preferred_name": "TATA-BOX-BINDING PROTEIN-ASSOCIATED FACTOR 11-LIKE PROTEIN 10-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46377:SF1", "l": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 19", "d": [], "t": []}], "preferred_name": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31183", "l": "TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "TRICHOPLEIN KERATIN FILAMENT-BINDING PROTEIN FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46404:SF1", "l": "DNA POLYMERASE IOTA", "d": [], "t": []}], "preferred_name": "DNA POLYMERASE IOTA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12608:SF1", "l": "TRANSMEMBRANE PROTEIN 165", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 165", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10762:SF2", "l": "2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2", "d": [], "t": []}], "preferred_name": "2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19302:SF14", "l": "GAMMA-TUBULIN COMPLEX COMPONENT 3", "d": [], "t": []}], "preferred_name": "GAMMA-TUBULIN COMPLEX COMPONENT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45775:SF4", "l": "GTP-BINDING PROTEIN GEM", "d": [], "t": []}], "preferred_name": "GTP-BINDING PROTEIN GEM", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14024:SF9", "l": "PERILIPIN-5", "d": [], "t": []}], "preferred_name": "PERILIPIN-5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3501", "l": "HOOK related protein family", "d": ["Hook-related proteins (HkRP) like Girdin (CCDC88A), DAPLE (CCDC88C), and Gipie (CCDC88B) are actin-binding proteins, implicated in actin organization and in cell motility."], "t": []}], "preferred_name": "HOOK related protein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19290:SF171", "l": "NEUROGENIN-2", "d": [], "t": []}], "preferred_name": "NEUROGENIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26454:SF17", "l": "OLFACTORY RECEPTOR 6C70", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 6C70", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48092:SF7", "l": "STEROID HORMONE RECEPTOR ERR2", "d": [], "t": []}], "preferred_name": "STEROID HORMONE RECEPTOR ERR2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11346:SF15", "l": "PLACENTAL PROTEIN 13-LIKE", "d": [], "t": []}], "preferred_name": "PLACENTAL PROTEIN 13-LIKE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24034:SF96", "l": "EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2", "d": [], "t": []}], "preferred_name": "EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32222", "l": "CENTROMERE PROTEIN U", "d": [], "t": []}], "preferred_name": "CENTROMERE PROTEIN U", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16234:SF5", "l": "AFG2-INTERACTING RIBOSOME MATURATION FACTOR", "d": [], "t": []}], "preferred_name": "AFG2-INTERACTING RIBOSOME MATURATION FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18843", "l": "TORSIN-1A-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "TORSIN-1A-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21454", "l": "DPH3 HOMOLOG-RELATED", "d": [], "t": []}], "preferred_name": "DPH3 HOMOLOG-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12974:SF30", "l": "TERMINAL NUCLEOTIDYLTRANSFERASE 5D", "d": [], "t": []}], "preferred_name": "TERMINAL NUCLEOTIDYLTRANSFERASE 5D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13589", "l": "CREB-REGULATED TRANSCRIPTION COACTIVATOR", "d": [], "t": []}], "preferred_name": "CREB-REGULATED TRANSCRIPTION COACTIVATOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22911", "l": "ACYL-MALONYL CONDENSING ENZYME-RELATED", "d": [], "t": []}], "preferred_name": "ACYL-MALONYL CONDENSING ENZYME-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12103:SF38", "l": "5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1082", "l": "Bisphosphoglycerate phosphatases", "d": ["In enzymology, a bisphosphoglycerate phosphatase ( EC 3.1.3.13 ) is an enzyme that catalyzes the chemical reaction  2,3-bisphospho-D-glycerate + H 2 O 3-phospho-D-glycerate + phosphate  Thus, the two substrates of this enzyme are 2,3-bisphospho-D-glycerate and H 2 O, whereas its two products are 3-phospho-D-glycerate and phosphate."], "t": []}], "preferred_name": "Bisphosphoglycerate phosphatases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10858:SF9", "l": "DEOXYRIBONUCLEASE-2-ALPHA", "d": [], "t": []}], "preferred_name": "DEOXYRIBONUCLEASE-2-ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11994", "l": "60S RIBOSOMAL PROTEIN L11-RELATED", "d": [], "t": []}], "preferred_name": "60S RIBOSOMAL PROTEIN L11-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1993", "l": "Long non-coding RNAs with FAM root symbol", "d": ["Homologous long non-coding RNA genes may be named together using the root symbol FAM# for 'family with sequence similarity'. Note that this root symbol is also used for protein coding families - this gene groups shows only the non-coding genes named with the FAM# root."], "t": []}], "preferred_name": "Long non-coding RNAs with FAM root symbol", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10507", "l": "CDC45-RELATED PROTEIN", "d": [], "t": []}], "preferred_name": "CDC45-RELATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15282", "l": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3", "d": [], "t": []}], "preferred_name": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 1, 3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28682:SF1", "l": "INHIBITORY SYNAPTIC FACTOR 2A", "d": [], "t": []}], "preferred_name": "INHIBITORY SYNAPTIC FACTOR 2A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24356:SF170", "l": "PROTEIN KINASE C ZETA TYPE", "d": [], "t": []}], "preferred_name": "PROTEIN KINASE C ZETA TYPE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17378:SF1", "l": "SECRETIN", "d": [], "t": []}], "preferred_name": "SECRETIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14963", "l": "RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED", "d": [], "t": []}], "preferred_name": "RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22406:SF2", "l": "SLAIN MOTIF-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "SLAIN MOTIF-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10845:SF160", "l": "REGULATOR OF G-PROTEIN SIGNALING 21", "d": [], "t": []}], "preferred_name": "REGULATOR OF G-PROTEIN SIGNALING 21", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23266:SF238", "l": "IMMUNOGLOBULIN HEAVY VARIABLE 4-34", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN HEAVY VARIABLE 4-34", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23233:SF46", "l": "SAL-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "SAL-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11890:SF18", "l": "LYMPHOCYTE ACTIVATION GENE 3 PROTEIN", "d": [], "t": []}], "preferred_name": "LYMPHOCYTE ACTIVATION GENE 3 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24192:SF1", "l": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 40", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 40", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24247:SF20", "l": "5-HYDROXYTRYPTAMINE RECEPTOR 1A", "d": [], "t": []}], "preferred_name": "5-HYDROXYTRYPTAMINE RECEPTOR 1A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18806", "l": "RBM25 PROTEIN", "d": [], "t": []}], "preferred_name": "RBM25 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22882:SF3", "l": "SYNPHILIN-1", "d": [], "t": []}], "preferred_name": "SYNPHILIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3465", "l": "Retrotransposon derived ASPRV1", "d": ["ASPRV1 is one of the human genes that have been domesticated from retrotransposons during vertebrate evolution. The protein expressed from this gene was defined as a retrovirus Gag-like protein as — besides its enzymatic domain — it contains a domain that is homologous to that of the Gag structural domain of the canonical retroviral polyprotein. The evolutionary origin was demonstrated by the homology between its Gag-like and protease domains and those of the retrovirus/retrotransposon proteins."], "t": []}], "preferred_name": "Retrotransposon derived ASPRV1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47899", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 171", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 171", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19957:SF212", "l": "T-SNARE DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "T-SNARE DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16265", "l": "PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "PTB-CONTAINING, CUBILIN AND LRP1-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10794:SF60", "l": "PROTEIN ABHD1", "d": [], "t": []}], "preferred_name": "PROTEIN ABHD1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11188:SF172", "l": "ARRESTIN DOMAIN-CONTAINING PROTEIN 5", "d": [], "t": []}], "preferred_name": "ARRESTIN DOMAIN-CONTAINING PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15696", "l": "SMG-7  SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7", "d": [], "t": []}], "preferred_name": "SMG-7  SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:542", "l": "Receptor ligands", "d": [], "t": []}], "preferred_name": "Receptor ligands", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13208", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15427:SF3", "l": "MULTIMERIN-1", "d": [], "t": []}], "preferred_name": "MULTIMERIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14112:SF26", "l": "PROTEIN SSX1", "d": [], "t": []}], "preferred_name": "PROTEIN SSX1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21530:SF7", "l": "TRAB DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "TRAB DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24418:SF245", "l": "TYROSINE-PROTEIN KINASE HCK", "d": [], "t": []}], "preferred_name": "TYROSINE-PROTEIN KINASE HCK", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14119:SF3", "l": "ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13383", "l": "RIBONUCLEASE H2 SUBUNIT B", "d": [], "t": []}], "preferred_name": "RIBONUCLEASE H2 SUBUNIT B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10071:SF23", "l": "TRANSCRIPTION FACTOR GATA-6", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR GATA-6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17695:SF11", "l": "SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG", "d": [], "t": []}], "preferred_name": "SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45747:SF1", "l": "HISTONE-LYSINE N-METHYLTRANSFERASE EZH1", "d": [], "t": []}], "preferred_name": "HISTONE-LYSINE N-METHYLTRANSFERASE EZH1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12021:SF20", "l": "THYMOSIN BETA-4", "d": [], "t": []}], "preferred_name": "THYMOSIN BETA-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31481:SF0", "l": "RELT-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "RELT-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22776:SF29", "l": "CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4", "d": [], "t": []}], "preferred_name": "CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24103:SF696", "l": "E3 UBIQUITIN-PROTEIN LIGASE TRIM41", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE TRIM41", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12713:SF5", "l": "V-TYPE PROTON ATPASE SUBUNIT G 3", "d": [], "t": []}], "preferred_name": "V-TYPE PROTON ATPASE SUBUNIT G 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28581", "l": "CONSORTIN", "d": [], "t": []}], "preferred_name": "CONSORTIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15605:SF2", "l": "KINESIN-ASSOCIATED PROTEIN 3", "d": [], "t": []}], "preferred_name": "KINESIN-ASSOCIATED PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11993", "l": "NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14057:SF34", "l": "ONE CUT DOMAIN FAMILY MEMBER 3", "d": [], "t": []}], "preferred_name": "ONE CUT DOMAIN FAMILY MEMBER 3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3507", "l": "MCU complex subunits", "d": ["The mitochondrial calcium uniporter channel exists as a channel composed of a total of 4 MCU subunits and up to 4 SMDT1 subunits. In some cases, the dominant-negative MCU paralog, MCUB, replaces MCU subunits within the complex. The channel is gated by dimers of MICU1/2 or, in some tissues, dimers of MICU1/3. The accessory subunit MCUR1 also binds to and regulates the channel. Two uniporter channels can dimerize, and the function of these dimers is regulated by interactions between the MICU2 subunit associated with each channel."], "t": []}], "preferred_name": "MCU complex subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11157:SF118", "l": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7", "d": [], "t": []}], "preferred_name": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2226", "l": "NHERF family PDZ scaffold proteins", "d": [], "t": []}], "preferred_name": "NHERF family PDZ scaffold proteins", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24046", "l": "SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING", "d": [], "t": []}], "preferred_name": "SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21128", "l": "FETAL AND ADULT TESTIS-EXPRESSED TRANSCRIPT PROTEIN", "d": [], "t": []}], "preferred_name": "FETAL AND ADULT TESTIS-EXPRESSED TRANSCRIPT PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35453", "l": "PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "PROSTATE ANDROGEN-REGULATED MUCIN-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28603", "l": "TRANSMEMBRANE PROTEIN 243", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 243", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10166:SF25", "l": "VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-3", "d": [], "t": []}], "preferred_name": "VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14907:SF3", "l": "SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10462:SF33", "l": "ALPHA-1,3-GALACTOSYLTRANSFERASE 2", "d": [], "t": []}], "preferred_name": "ALPHA-1,3-GALACTOSYLTRANSFERASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12138", "l": "PRIMATE-EXPANDED PROTEIN FAMILY", "d": [], "t": []}], "preferred_name": "PRIMATE-EXPANDED PROTEIN FAMILY", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24211", "l": "LIM DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "LIM DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22574:SF6", "l": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 2", "d": [], "t": []}], "preferred_name": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11568:SF2", "l": "HEPATOCYTE NUCLEAR FACTOR 1-BETA", "d": [], "t": []}], "preferred_name": "HEPATOCYTE NUCLEAR FACTOR 1-BETA", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23086:SF46", "l": "PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46789:SF2", "l": "FORKHEAD BOX PROTEIN R2", "d": [], "t": []}], "preferred_name": "FORKHEAD BOX PROTEIN R2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45656:SF3", "l": "CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10605:SF53", "l": "BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 2", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11852", "l": "PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE", "d": [], "t": []}], "preferred_name": "PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24418:SF269", "l": "TYROSINE-PROTEIN KINASE STYK1", "d": [], "t": []}], "preferred_name": "TYROSINE-PROTEIN KINASE STYK1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12125:SF13", "l": "F-BOX ONLY PROTEIN 44", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 44", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23206:SF1", "l": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 17", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12944", "l": "SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN", "d": [], "t": []}], "preferred_name": "SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12011:SF455", "l": "ADHESION G PROTEIN-COUPLED RECEPTOR E3", "d": [], "t": []}], "preferred_name": "ADHESION G PROTEIN-COUPLED RECEPTOR E3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47079:SF1", "l": "REGULATOR OF G-PROTEIN SIGNALING PROTEIN-LIKE", "d": [], "t": []}], "preferred_name": "REGULATOR OF G-PROTEIN SIGNALING PROTEIN-LIKE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13498", "l": "SPERM ASSOCIATED ANTIGEN 7", "d": [], "t": []}], "preferred_name": "SPERM ASSOCIATED ANTIGEN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15561:SF0", "l": "DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9", "d": [], "t": []}], "preferred_name": "DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24270:SF24", "l": "LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45771:SF9", "l": "HOMEOBOX PROTEIN HOX-C4", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN HOX-C4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13748", "l": "COBW-RELATED", "d": [], "t": []}], "preferred_name": "COBW-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18934:SF95", "l": "ATP-DEPENDENT RNA HELICASE DHX15", "d": [], "t": []}], "preferred_name": "ATP-DEPENDENT RNA HELICASE DHX15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45656", "l": "PROTEIN CBR-CLEC-78", "d": [], "t": []}], "preferred_name": "PROTEIN CBR-CLEC-78", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28492", "l": "HYPOTHETICAL PROTEIN LOC691921", "d": [], "t": []}], "preferred_name": "HYPOTHETICAL PROTEIN LOC691921", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23280:SF17", "l": "BAND 4.1-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "BAND 4.1-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14499:SF4", "l": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD18", "d": [], "t": []}], "preferred_name": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47135:SF1", "l": "FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7", "d": [], "t": []}], "preferred_name": "FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11985:SF29", "l": "GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24099:SF7", "l": "CARDIOMYOPATHY-ASSOCIATED PROTEIN 5", "d": [], "t": []}], "preferred_name": "CARDIOMYOPATHY-ASSOCIATED PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14819:SF5", "l": "INTERFERON-INDUCED VERY LARGE GTPASE 1", "d": [], "t": []}], "preferred_name": "INTERFERON-INDUCED VERY LARGE GTPASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10288:SF166", "l": "POLY(RC)-BINDING PROTEIN 4", "d": [], "t": []}], "preferred_name": "POLY(RC)-BINDING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10554:SF8", "l": "BETA-2-SYNTROPHIN", "d": [], "t": []}], "preferred_name": "BETA-2-SYNTROPHIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45745:SF3", "l": "PHOSPHOPENTOMUTASE", "d": [], "t": []}], "preferred_name": "PHOSPHOPENTOMUTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1695", "l": "SWC tripartite complex", "d": [], "t": []}], "preferred_name": "SWC tripartite complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1133", "l": "Arylamine N-acetyltransferases", "d": ["In enzymology, an arylamine N-acetyltransferase ( EC 2.3.1.5 ) is an enzyme that catalyzes the chemical reaction  acetyl-CoA + an arylamine CoA + an N-acetylarylamine  Thus, the two substrates of this enzyme are acetyl-CoA and arylamine, whereas its two products are CoA and N-acetylarylamine.  This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:arylamine N-acetyltransferase. Other names in common use include arylamine acetylase, beta-naphthylamine N-acetyltransferase, 4-aminobiphenyl N-acetyltransferase, acetyl CoA-arylamine N-acetyltransferase, 2-naphthylamine N-acetyltransferase, arylamine acetyltransferase, indoleamine N-acetyltransferase, N-acetyltransferase, p-aminosalicylate N-acetyltransferase, serotonin acetyltransferase, and serotonin N-acetyltransferase."], "t": []}], "preferred_name": "Arylamine N-acetyltransferases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44566", "l": "TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN", "d": [], "t": []}], "preferred_name": "TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36129", "l": "ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED", "d": [], "t": []}], "preferred_name": "ORGANIC SOLUTE TRANSPORTER SUBUNIT BETA-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR40386", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 26", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 26", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46032:SF4", "l": "CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2", "d": [], "t": []}], "preferred_name": "CMP-N-ACETYLNEURAMINATE-BETA-GALACTOSAMIDE-ALPHA-2,3-SIALYLTRANSFERASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12587:SF5", "l": "LIPRIN-ALPHA-4", "d": [], "t": []}], "preferred_name": "LIPRIN-ALPHA-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47522:SF2", "l": "PROTEIN SALVADOR HOMOLOG 1", "d": [], "t": []}], "preferred_name": "PROTEIN SALVADOR HOMOLOG 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12472:SF0", "l": "RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT", "d": [], "t": []}], "preferred_name": "RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46569:SF1", "l": "E3 UBIQUITIN-PROTEIN LIGASE RFWD3-RELATED", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RFWD3-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46491", "l": "CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG", "d": [], "t": []}], "preferred_name": "CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10218:SF329", "l": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(Q) SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43066:SF16", "l": "RHOMBOID DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "RHOMBOID DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14275:SF0", "l": "LIPID DROPLET ASSEMBLY FACTOR 1", "d": [], "t": []}], "preferred_name": "LIPID DROPLET ASSEMBLY FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24388:SF42", "l": "ZINC FINGER PROTEIN SNAI2", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN SNAI2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45965:SF4", "l": "INACTIVE RHOMBOID PROTEIN 1", "d": [], "t": []}], "preferred_name": "INACTIVE RHOMBOID PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11532", "l": "PROTEASE M14 CARBOXYPEPTIDASE", "d": [], "t": []}], "preferred_name": "PROTEASE M14 CARBOXYPEPTIDASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2136", "l": "NUAK family kinases", "d": [], "t": []}], "preferred_name": "NUAK family kinases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2317", "l": "Neurexophilin domain containing", "d": [], "t": []}], "preferred_name": "Neurexophilin domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13617", "l": "PROTEIN ABHD18", "d": [], "t": []}], "preferred_name": "PROTEIN ABHD18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12791:SF37", "l": "BET1-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "BET1-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31697:SF2", "l": "INTEGRATOR COMPLEX SUBUNIT 5", "d": [], "t": []}], "preferred_name": "INTEGRATOR COMPLEX SUBUNIT 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21064:SF1", "l": "HYDROXYLYSINE KINASE", "d": [], "t": []}], "preferred_name": "HYDROXYLYSINE KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35451:SF1", "l": "NEUROPEPTIDE-LIKE PROTEIN C4ORF48", "d": [], "t": []}], "preferred_name": "NEUROPEPTIDE-LIKE PROTEIN C4ORF48", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3902", "l": "Purine rich element binding protein family", "d": ["The Pur proteins are an ancient family of sequence-specific single-stranded nucleic acid-binding proteins. They bind a G-rich element in either single- or double-stranded nucleic acids and are capable of displacing the complementary C-rich strand. In humans Pur proteins are critical for myeloid cell development, muscle development, and brain development, including trafficking of mRNA to neuronal dendrites. Pur family members have been implicated in diseases as diverse as cancer, premature aging, and fragile-X syndrome."], "t": []}], "preferred_name": "Purine rich element binding protein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11348:SF7", "l": "CCN FAMILY MEMBER 2", "d": [], "t": []}], "preferred_name": "CCN FAMILY MEMBER 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10015:SF336", "l": "HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED", "d": [], "t": []}], "preferred_name": "HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14938:SF2", "l": "HCLS1-ASSOCIATED PROTEIN X-1", "d": [], "t": []}], "preferred_name": "HCLS1-ASSOCIATED PROTEIN X-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15832:SF1", "l": "HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3", "d": [], "t": []}], "preferred_name": "HETEROCHROMATIN PROTEIN 1-BINDING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46840:SF1", "l": "ARMADILLO REPEAT-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "ARMADILLO REPEAT-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1717", "l": "MicroRNA MIR148/152 family", "d": ["In molecular biology, miR-148 is a microRNA whose expression has been demonstrated in human (MI0000253), mouse (MI0000550), rat (MI0000616) and zebrafish (MI0002015). miR-148 has also been predicted in chicken (MI0001189).  These predicted hairpin precursor sequence are related to those of miR-152, which has been expressed in mouse (MI0000174) and is predicted in human (MI0000462).The hairpin precursors (represented here) are predicted based on base pairing and cross-species conservation; their extents are not known. In this case, the mature sequence is excised from the 3' arm of the hairpin."], "t": []}], "preferred_name": "MicroRNA MIR148/152 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31733", "l": "RIBONUCLEASE KAPPA", "d": [], "t": []}], "preferred_name": "RIBONUCLEASE KAPPA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:161", "l": "Ligand gated ion channels", "d": ["Ligand-gated ion channels (LGICs) are a group of transmembrane ion channel proteins which open to allow ions such as Na +, K +, Ca 2+, or Cl - to pass through the membrane in response to the binding of a chemical messenger (i.e. a ligand ), such as a neurotransmitter.  These proteins are typically composed of at least two different domains: a transmembrane domain which includes the ion pore, and an extracellular domain which includes the ligand binding location (an allosteric binding site). This modularity has enabled a 'divide and conquer' approach to finding the structure of the proteins (crystallising each domain separately). The function of such receptors located at synapses is to convert the chemical signal of presynaptically released neurotransmitter directly and very quickly into a postsynaptic electrical signal. Many LGICs are additionally modulated by allosteric ligands, by channel blockers, ions, or the membrane potential. LGICs are classified into three superfamilies which lack evolutionary relationship: Cys-loop receptors, Ionotropic glutamate receptors and ATP-gated channels."], "t": []}], "preferred_name": "Ligand gated ion channels", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19957:SF124", "l": "SYNTAXIN-8", "d": [], "t": []}], "preferred_name": "SYNTAXIN-8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13890", "l": "RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46102", "l": "AXIN", "d": [], "t": []}], "preferred_name": "AXIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF142", "l": "ZINC FINGER PROTEIN 546", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 546", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48083:SF35", "l": "ACYL-COA DEHYDROGENASE FAMILY MEMBER 10", "d": [], "t": []}], "preferred_name": "ACYL-COA DEHYDROGENASE FAMILY MEMBER 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10584", "l": "SUGAR KINASE", "d": [], "t": []}], "preferred_name": "SUGAR KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47231", "l": "UPF0722 PROTEIN C11ORF88", "d": [], "t": []}], "preferred_name": "UPF0722 PROTEIN C11ORF88", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23405", "l": "MAINTENANCE OF KILLER 16  MAK16  PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "MAINTENANCE OF KILLER 16  MAK16  PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16106:SF3", "l": "CHROMOSOME 4 OPEN READING FRAME 19", "d": [], "t": []}], "preferred_name": "CHROMOSOME 4 OPEN READING FRAME 19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11932:SF174", "l": "CULLIN-2", "d": [], "t": []}], "preferred_name": "CULLIN-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10259", "l": "THIOPURINE S-METHYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "THIOPURINE S-METHYLTRANSFERASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37367:SF1", "l": "CHROMOSOME 4 OPEN READING FRAME 3", "d": [], "t": []}], "preferred_name": "CHROMOSOME 4 OPEN READING FRAME 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24064", "l": "SOLUTE CARRIER FAMILY 22 MEMBER", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 22 MEMBER", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11740", "l": "CASEIN KINASE II SUBUNIT BETA", "d": [], "t": []}], "preferred_name": "CASEIN KINASE II SUBUNIT BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46756:SF7", "l": "GAS2-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "GAS2-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23350:SF0", "l": "PEROXISOME BIOGENESIS FACTOR 10", "d": [], "t": []}], "preferred_name": "PEROXISOME BIOGENESIS FACTOR 10", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12920:SF3", "l": "RING1 AND YY1-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "RING1 AND YY1-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15344:SF15", "l": "CDC42 EFFECTOR PROTEIN 5", "d": [], "t": []}], "preferred_name": "CDC42 EFFECTOR PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10155:SF5", "l": "SUPPRESSOR OF CYTOKINE SIGNALING 7", "d": [], "t": []}], "preferred_name": "SUPPRESSOR OF CYTOKINE SIGNALING 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21294:SF8", "l": "ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA", "d": [], "t": []}], "preferred_name": "ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46049:SF5", "l": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3", "d": [], "t": []}], "preferred_name": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF274", "l": "PLASMA SERINE PROTEASE INHIBITOR", "d": [], "t": []}], "preferred_name": "PLASMA SERINE PROTEASE INHIBITOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42985:SF10", "l": "SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1", "d": [], "t": []}], "preferred_name": "SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45921", "l": "IP01054P", "d": [], "t": []}], "preferred_name": "IP01054P", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13856:SF31", "l": "TOM1-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "TOM1-LIKE PROTEIN 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24393:SF69", "l": "HISTONE-LYSINE N-METHYLTRANSFERASE MECOM", "d": [], "t": []}], "preferred_name": "HISTONE-LYSINE N-METHYLTRANSFERASE MECOM", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1763", "l": "MicroRNA MIR216 family", "d": [], "t": []}], "preferred_name": "MicroRNA MIR216 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46025:SF2", "l": "XYLOSYLTRANSFERASE 1", "d": [], "t": []}], "preferred_name": "XYLOSYLTRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11848:SF29", "l": "INHIBIN BETA B CHAIN", "d": [], "t": []}], "preferred_name": "INHIBIN BETA B CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12002:SF17", "l": "CLAUDIN-20", "d": [], "t": []}], "preferred_name": "CLAUDIN-20", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12490", "l": "GSK3B-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "GSK3B-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15215:SF2", "l": "PROTEIN THEMIS2", "d": [], "t": []}], "preferred_name": "PROTEIN THEMIS2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3621", "l": "Protein prenyltransferases", "d": ["Protein prenylation is a post-translational modification controlling the localization, activity, and protein-protein interactions of small GTPases, including the Ras superfamily. This covalent attachment of either a farnesyl (15 carbon) or a geranylgeranyl (20 carbon) isoprenoid group is catalyzed by four prenyltransferases, namely farnesyltransferase (FTase), geranylgeranyltransferase type I (GGTase-I), Rab geranylgeranyltransferase (GGTase-II), and geranylgeranyltransferase type III (GGTase-III)."], "t": []}], "preferred_name": "Protein prenyltransferases", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28664", "l": "TIGHT JUNCTION-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "TIGHT JUNCTION-ASSOCIATED PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11886:SF2", "l": "DYNEIN AXONEMAL LIGHT CHAIN 4", "d": [], "t": []}], "preferred_name": "DYNEIN AXONEMAL LIGHT CHAIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13563:SF13", "l": "TRNA METHYLTRANSFERASE 10 HOMOLOG A", "d": [], "t": []}], "preferred_name": "TRNA METHYLTRANSFERASE 10 HOMOLOG A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46582:SF1", "l": "ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18", "d": [], "t": []}], "preferred_name": "ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2142", "l": "Serine hydroxymethyltransferase family", "d": [], "t": []}], "preferred_name": "Serine hydroxymethyltransferase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23284", "l": "PROLACTIN REGULATORY ELEMENT BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "PROLACTIN REGULATORY ELEMENT BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46263:SF1", "l": "ARMADILLO REPEAT-CONTAINING PROTEIN 7", "d": [], "t": []}], "preferred_name": "ARMADILLO REPEAT-CONTAINING PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24416:SF130", "l": "FIBROBLAST GROWTH FACTOR RECEPTOR 2", "d": [], "t": []}], "preferred_name": "FIBROBLAST GROWTH FACTOR RECEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32008:SF2", "l": "MATURIN", "d": [], "t": []}], "preferred_name": "MATURIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14659:SF1", "l": "ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34", "d": [], "t": []}], "preferred_name": "ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18952:SF91", "l": "CARBONIC ANHYDRASE-RELATED PROTEIN 10", "d": [], "t": []}], "preferred_name": "CARBONIC ANHYDRASE-RELATED PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37880", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 54", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 54", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11118", "l": "RNA-SPLICING LIGASE RTCB HOMOLOG", "d": [], "t": []}], "preferred_name": "RNA-SPLICING LIGASE RTCB HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2050", "l": "Adducin family", "d": [], "t": []}], "preferred_name": "Adducin family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16356", "l": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11442:SF42", "l": "HEMOGLOBIN SUBUNIT BETA", "d": [], "t": []}], "preferred_name": "HEMOGLOBIN SUBUNIT BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1016", "l": "Cytochrome P450 family 46", "d": [], "t": []}], "preferred_name": "Cytochrome P450 family 46", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12570:SF1", "l": "MAGNESIUM TRANSPORTER NIPA2", "d": [], "t": []}], "preferred_name": "MAGNESIUM TRANSPORTER NIPA2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24230:SF51", "l": "LEUKOTRIENE B4 RECEPTOR 1", "d": [], "t": []}], "preferred_name": "LEUKOTRIENE B4 RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1240", "l": "Tubulin polymerization promoting proteins", "d": [], "t": []}], "preferred_name": "Tubulin polymerization promoting proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12463", "l": "OXYGENASE-RELATED", "d": [], "t": []}], "preferred_name": "OXYGENASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20870", "l": "BARDET-BIEDL SYNDROME 1 PROTEIN", "d": [], "t": []}], "preferred_name": "BARDET-BIEDL SYNDROME 1 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47083:SF1", "l": "TESTIS-EXPRESSED PROTEIN 11", "d": [], "t": []}], "preferred_name": "TESTIS-EXPRESSED PROTEIN 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21637:SF1", "l": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD20", "d": [], "t": []}], "preferred_name": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD20", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22625:SF35", "l": "PLEXIN-A1", "d": [], "t": []}], "preferred_name": "PLEXIN-A1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12713:SF12", "l": "V-TYPE PROTON ATPASE SUBUNIT G 1", "d": [], "t": []}], "preferred_name": "V-TYPE PROTON ATPASE SUBUNIT G 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23044", "l": "3'-5' EXONUCLEASE ERI1-RELATED", "d": [], "t": []}], "preferred_name": "3'-5' EXONUCLEASE ERI1-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11818:SF101", "l": "GAMMA-CRYSTALLIN B", "d": [], "t": []}], "preferred_name": "GAMMA-CRYSTALLIN B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13935:SF66", "l": "ACHAETE-SCUTE HOMOLOG 1", "d": [], "t": []}], "preferred_name": "ACHAETE-SCUTE HOMOLOG 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43981", "l": "ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10551", "l": "FASCIN", "d": [], "t": []}], "preferred_name": "FASCIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24223:SF241", "l": "MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:785", "l": "Ubiquitin protein ligase E3 component n-recognins", "d": [], "t": []}], "preferred_name": "Ubiquitin protein ligase E3 component n-recognins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24184", "l": "SI:CH211-189E2.2", "d": [], "t": []}], "preferred_name": "SI:CH211-189E2.2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10048:SF35", "l": "PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31901:SF9", "l": "GH3 DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "GH3 DOMAIN-CONTAINING PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12151", "l": "ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11567:SF202", "l": "LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6", "d": [], "t": []}], "preferred_name": "LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12645", "l": "ALR/ERV", "d": [], "t": []}], "preferred_name": "ALR/ERV", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39235:SF1", "l": "PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22639", "l": "GAG-RELATED PROTEIN", "d": [], "t": []}], "preferred_name": "GAG-RELATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47401", "l": "INTERLEUKIN-4", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11467:SF14", "l": "TESTIS-SPECIFIC H1 HISTONE", "d": [], "t": []}], "preferred_name": "TESTIS-SPECIFIC H1 HISTONE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11010:SF107", "l": "DIPEPTIDYL PEPTIDASE 2", "d": [], "t": []}], "preferred_name": "DIPEPTIDYL PEPTIDASE 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12775:SF0", "l": "REPLICATION TERMINATION FACTOR 2", "d": [], "t": []}], "preferred_name": "REPLICATION TERMINATION FACTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11588:SF4", "l": "TUBULIN DELTA CHAIN", "d": [], "t": []}], "preferred_name": "TUBULIN DELTA CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39233:SF1", "l": "FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 10", "d": [], "t": []}], "preferred_name": "FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28641:SF1", "l": "MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15359:SF5", "l": "PURKINJE CELL PROTEIN 4-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "PURKINJE CELL PROTEIN 4-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:282", "l": "Glutamate receptors", "d": ["Glutamate receptors are synaptic receptors located primarily on the membranes of neuronal cells. Glutamate (glutamic acid) is abundant in the human body, but particularly in the nervous system and especially prominent in the human brain where it is the body's most prominent neurotransmitter, the brain's main excitatory neurotransmitter, and also the precursor for GABA, the brain's main inhibitory neurotransmitter. Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation.  Glutamate receptors are implicated in a number of neurological conditions. Their central role in excitotoxicity and prevalence in the central nervous system has been linked or speculated to be linked to many neurodegenerative diseases, and several other conditions have been further linked to glutamate receptor gene mutations or receptor autoantigen /antibody activity."], "t": []}], "preferred_name": "Glutamate receptors", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23086:SF22", "l": "PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 BETA", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11528:SF87", "l": "HEAT SHOCK PROTEIN HSP 90-ALPHA", "d": [], "t": []}], "preferred_name": "HEAT SHOCK PROTEIN HSP 90-ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13261", "l": "BRCA2 AND CDKN1A INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "BRCA2 AND CDKN1A INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23058", "l": "PEROXISOMAL MEMBRANE PROTEIN PEX14", "d": [], "t": []}], "preferred_name": "PEROXISOMAL MEMBRANE PROTEIN PEX14", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10740:SF1", "l": "PROTRANSFORMING GROWTH FACTOR ALPHA", "d": [], "t": []}], "preferred_name": "PROTRANSFORMING GROWTH FACTOR ALPHA", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12707", "l": "PINN", "d": [], "t": []}], "preferred_name": "PINN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11588:SF113", "l": "TUBULIN ALPHA-3D CHAIN", "d": [], "t": []}], "preferred_name": "TUBULIN ALPHA-3D CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10625:SF23", "l": "HISTONE DEACETYLASE 11", "d": [], "t": []}], "preferred_name": "HISTONE DEACETYLASE 11", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:889", "l": "T cell receptor beta", "d": [], "t": []}], "preferred_name": "T cell receptor beta", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21255:SF19", "l": "DYNEIN LIGHT CHAIN TCTEX-TYPE 1", "d": [], "t": []}], "preferred_name": "DYNEIN LIGHT CHAIN TCTEX-TYPE 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23058:SF0", "l": "PEROXISOMAL MEMBRANE PROTEIN PEX14", "d": [], "t": []}], "preferred_name": "PEROXISOMAL MEMBRANE PROTEIN PEX14", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13455:SF3", "l": "TRANSCRIPTIONAL REPRESSOR P66-ALPHA", "d": [], "t": []}], "preferred_name": "TRANSCRIPTIONAL REPRESSOR P66-ALPHA", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31036:SF0", "l": "FANCD2 OPPOSITE STRAND PROTEIN", "d": [], "t": []}], "preferred_name": "FANCD2 OPPOSITE STRAND PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10183:SF381", "l": "CALPAIN-6", "d": [], "t": []}], "preferred_name": "CALPAIN-6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11599", "l": "PROTEASOME SUBUNIT ALPHA/BETA", "d": [], "t": []}], "preferred_name": "PROTEASOME SUBUNIT ALPHA/BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21502:SF6", "l": "RILP-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "RILP-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2022", "l": "Oxoglutarate dehydrogenase complex subunits", "d": [], "t": []}], "preferred_name": "Oxoglutarate dehydrogenase complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19375:SF379", "l": "HEAT SHOCK COGNATE 71 KDA PROTEIN", "d": [], "t": []}], "preferred_name": "HEAT SHOCK COGNATE 71 KDA PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46170", "l": "GATOR COMPLEX PROTEIN WDR59", "d": [], "t": []}], "preferred_name": "GATOR COMPLEX PROTEIN WDR59", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF315", "l": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-1", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13124", "l": "39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED", "d": [], "t": []}], "preferred_name": "39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36477", "l": "TRANSMEMBRANE PROTEIN 225", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 225", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3725", "l": "Muscleblind like splicing regulator family", "d": ["As RNA-binding proteins, MBNL family members interact with pre-mRNAs through evolutionarily conserved tandem zinc finger domains and play critical roles in various RNA metabolic processes, including alternative splicing, mRNA stability, trafficking, regulation of subcellular localization, and alternative polyadenylation. Dysregulation of MBNL proteins can lead to severe consequences. Initially, research primarily associated MBNL proteins with myotonic dystrophy. However, subsequent studies have revealed their involvement in a broad spectrum of physiological and pathological processes, such as embryonic tissue differentiation and circulatory disorders."], "t": []}], "preferred_name": "Muscleblind like splicing regulator family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15337", "l": "ANTERIOR GRADIENT PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "ANTERIOR GRADIENT PROTEIN-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14202:SF0", "l": "RNA-BINDING PROTEIN RO60", "d": [], "t": []}], "preferred_name": "RNA-BINDING PROTEIN RO60", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2141", "l": "Bridge-like lipid transfer protein family", "d": ["Bridge-like lipid transporter proteins are key regulators of intraorganellar lipid trafficking. The BLTP proteins form physical bridges that span the gap between a donor and a receiver organelle and are are formed by multiple repeats of one motif: a repeating beta groove (RBG), which forms an extremely long semi-open tube with a hydrophobic interior."], "t": []}], "preferred_name": "Bridge-like lipid transfer protein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15256", "l": "INTEGRAL MEMBRANE PROTEIN DGCR2/IDD", "d": [], "t": []}], "preferred_name": "INTEGRAL MEMBRANE PROTEIN DGCR2/IDD", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43205:SF5", "l": "PROSTAGLANDIN REDUCTASE 2", "d": [], "t": []}], "preferred_name": "PROSTAGLANDIN REDUCTASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13555", "l": "C2H2 ZINC FINGER CGI-62-RELATED", "d": [], "t": []}], "preferred_name": "C2H2 ZINC FINGER CGI-62-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23249:SF15", "l": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4", "d": [], "t": []}], "preferred_name": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12176:SF80", "l": "EEF1A LYSINE METHYLTRANSFERASE 4", "d": [], "t": []}], "preferred_name": "EEF1A LYSINE METHYLTRANSFERASE 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15592:SF1", "l": "ZINC FINGER PROTEIN 638", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 638", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23247:SF2", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 34", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 34", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18861:SF3", "l": "ERC PROTEIN 2", "d": [], "t": []}], "preferred_name": "ERC PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3429", "l": "Hexokinase family", "d": ["Hexokinases phosphorylate a variety of hexose sugars, although their preferred substrate is glucose. GCK has a single hexokinase domain while the other family members have two hexokinase domains but only HK2 has been shown to have two active sites."], "t": []}], "preferred_name": "Hexokinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24373:SF285", "l": "INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT", "d": [], "t": []}], "preferred_name": "INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN COMPLEX ACID LABILE SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF425", "l": "ZINC FINGER PROTEIN 483", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 483", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34436", "l": "CENTROMERE PROTEIN M", "d": [], "t": []}], "preferred_name": "CENTROMERE PROTEIN M", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12141", "l": "ARFAPTIN-RELATED", "d": [], "t": []}], "preferred_name": "ARFAPTIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19282:SF470", "l": "TETRASPANIN-17", "d": [], "t": []}], "preferred_name": "TETRASPANIN-17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11630:SF73", "l": "DNA REPLICATION LICENSING FACTOR MCM6", "d": [], "t": []}], "preferred_name": "DNA REPLICATION LICENSING FACTOR MCM6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34649", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 99", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23239:SF165", "l": "IF ROD DOMAIN-CONTAINING PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "IF ROD DOMAIN-CONTAINING PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20921:SF0", "l": "TRANSMEMBRANE PROTEIN 222", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 222", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15379:SF2", "l": "CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1", "d": [], "t": []}], "preferred_name": "CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46165:SF2", "l": "SET AND MYND DOMAIN-CONTAINING PROTEIN 4", "d": [], "t": []}], "preferred_name": "SET AND MYND DOMAIN-CONTAINING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16074:SF4", "l": "BARDET-BIEDL SYNDROME 7 PROTEIN", "d": [], "t": []}], "preferred_name": "BARDET-BIEDL SYNDROME 7 PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23268:SF123", "l": "T CELL RECEPTOR BETA VARIABLE 5-8", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA VARIABLE 5-8", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45646", "l": "SERINE/THREONINE-PROTEIN KINASE DOA-RELATED", "d": [], "t": []}], "preferred_name": "SERINE/THREONINE-PROTEIN KINASE DOA-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12137:SF4", "l": "CARBOHYDRATE SULFOTRANSFERASE 12", "d": [], "t": []}], "preferred_name": "CARBOHYDRATE SULFOTRANSFERASE 12", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28601", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 24", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 24", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11534:SF4", "l": "MYOGENIC FACTOR 6", "d": [], "t": []}], "preferred_name": "MYOGENIC FACTOR 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46386:SF12", "l": "NUCLEAR AUTOANTIGEN SP-100", "d": [], "t": []}], "preferred_name": "NUCLEAR AUTOANTIGEN SP-100", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR38003:SF1", "l": "THYMIC STROMAL LYMPHOPOIETIN", "d": [], "t": []}], "preferred_name": "THYMIC STROMAL LYMPHOPOIETIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11818:SF11", "l": "BETA-CRYSTALLIN B2", "d": [], "t": []}], "preferred_name": "BETA-CRYSTALLIN B2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19290:SF99", "l": "TRANSCRIPTION FACTOR ATOH7", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR ATOH7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22891:SF3", "l": "PROTEIN ARGONAUTE-3", "d": [], "t": []}], "preferred_name": "PROTEIN ARGONAUTE-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11732:SF391", "l": "1,5-ANHYDRO-D-FRUCTOSE REDUCTASE", "d": [], "t": []}], "preferred_name": "1,5-ANHYDRO-D-FRUCTOSE REDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:904", "l": "Membrane associated guanylate kinases", "d": ["The membrane-associated guanylate kinases (MAGUK) are a superfamily of proteins. The MAGUKs are defined by their inclusion of PDZ, SH3 and GUK domains, although many of them also contain regions homologous of CaMKII, WW and L27 domains. The GUK domain that they have is structurally very similar to that of the guanylate kinases, however it is known to be catalytically inactive as the P-Loop which binds ATP is absent. It is thought that the MAGUKs have subfunctionalized the GUK domain for their own purposes, primarily based on its ability to form protein-protein interactions with cytoskeleton proteins, microtubule / actin based machinery and molecules involved in signal transduction.  The PDZ domain which are contained in the MAGUKs in varying numbers. PDZ domains are short peptide binding sequences commonly found at the C-terminus of interacting proteins. Copies within each of the family members often have different binding partners, due to amino acid differences between the copies. The SH3 domain is again a protein-protein interaction domain. Its family generally bind to PXXP sites, but in MAGUKs it is known to bind to other sites as well. One of the most well known features is that it can form an intramolecular bond with the GUK domain, creating what is known as a GUK-SH3 'closed' state."], "t": []}], "preferred_name": "Membrane associated guanylate kinases", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35670", "l": "TRANSMEMBRANE PROTEIN 81", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 81", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21355:SF0", "l": "G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2", "d": [], "t": []}], "preferred_name": "G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34651", "l": "SIMILAR TO ENSANGP00000021391", "d": [], "t": []}], "preferred_name": "SIMILAR TO ENSANGP00000021391", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF48", "l": "GLIA-DERIVED NEXIN", "d": [], "t": []}], "preferred_name": "GLIA-DERIVED NEXIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10925:SF5", "l": "RNA CYTIDINE ACETYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "RNA CYTIDINE ACETYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24381:SF111", "l": "ZINC FINGER PROTEIN 80", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 80", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16803", "l": "HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR GAMMA-SUBUNIT", "d": [], "t": []}], "preferred_name": "HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR GAMMA-SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12035:SF106", "l": "SIALIC ACID-BINDING IG-LIKE LECTIN 8", "d": [], "t": []}], "preferred_name": "SIALIC ACID-BINDING IG-LIKE LECTIN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46027", "l": "PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR", "d": [], "t": []}], "preferred_name": "PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17250", "l": "NEGATIVE ELONGATION FACTOR E", "d": [], "t": []}], "preferred_name": "NEGATIVE ELONGATION FACTOR E", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16955", "l": "METASTASIS-SUPPRESSOR KISS-1", "d": [], "t": []}], "preferred_name": "METASTASIS-SUPPRESSOR KISS-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13003:SF2", "l": "NUCLEAR PORE COMPLEX PROTEIN NUP107", "d": [], "t": []}], "preferred_name": "NUCLEAR PORE COMPLEX PROTEIN NUP107", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12920:SF2", "l": "YY1-ASSOCIATED FACTOR 2", "d": [], "t": []}], "preferred_name": "YY1-ASSOCIATED FACTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43684:SF1", "l": "ENOYL-COA DELTA ISOMERASE 2", "d": [], "t": []}], "preferred_name": "ENOYL-COA DELTA ISOMERASE 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12750:SF11", "l": "INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 1", "d": [], "t": []}], "preferred_name": "INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46526", "l": "CHORDIN", "d": [], "t": []}], "preferred_name": "CHORDIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11675:SF10", "l": "POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 11", "d": [], "t": []}], "preferred_name": "POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13151:SF2", "l": "COREPRESSOR INTERACTING WITH RBPJ 1", "d": [], "t": []}], "preferred_name": "COREPRESSOR INTERACTING WITH RBPJ 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21436:SF2", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 142", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 142", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13008:SF7", "l": "MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN", "d": [], "t": []}], "preferred_name": "MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22826:SF117", "l": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B-RELATED", "d": [], "t": []}], "preferred_name": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34929", "l": "ZGC:153157", "d": [], "t": []}], "preferred_name": "ZGC:153157", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11360:SF25", "l": "MONOCARBOXYLATE TRANSPORTER 2", "d": [], "t": []}], "preferred_name": "MONOCARBOXYLATE TRANSPORTER 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36135", "l": "FIBROUS SHEATH CABYR-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "FIBROUS SHEATH CABYR-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF477", "l": "IMMUNOGLOBULIN KAPPA VARIABLE 2D-26", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN KAPPA VARIABLE 2D-26", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16504:SF5", "l": "5'(3')-DEOXYRIBONUCLEOTIDASE, CYTOSOLIC TYPE", "d": [], "t": []}], "preferred_name": "5'(3')-DEOXYRIBONUCLEOTIDASE, CYTOSOLIC TYPE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1003", "l": "Cytochrome P450 family 4", "d": [], "t": []}], "preferred_name": "Cytochrome P450 family 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10738:SF0", "l": "PROTEIN ARGININE N-METHYLTRANSFERASE 5", "d": [], "t": []}], "preferred_name": "PROTEIN ARGININE N-METHYLTRANSFERASE 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF108", "l": "PROTOCADHERIN GAMMA-A1", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN GAMMA-A1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13100:SF10", "l": "CELL GROWTH-REGULATING NUCLEOLAR PROTEIN", "d": [], "t": []}], "preferred_name": "CELL GROWTH-REGULATING NUCLEOLAR PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12761", "l": "HERMANSKY-PUDLAK SYNDROME PROTEIN 1", "d": [], "t": []}], "preferred_name": "HERMANSKY-PUDLAK SYNDROME PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33958:SF1", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10824:SF17", "l": "ACYL-COENZYME A THIOESTERASE 6", "d": [], "t": []}], "preferred_name": "ACYL-COENZYME A THIOESTERASE 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11733", "l": "ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED", "d": [], "t": []}], "preferred_name": "ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1312", "l": "Classical arrestins", "d": [], "t": []}], "preferred_name": "Classical arrestins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31051:SF1", "l": "PROTEASOME ASSEMBLY CHAPERONE 3", "d": [], "t": []}], "preferred_name": "PROTEASOME ASSEMBLY CHAPERONE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10060", "l": "TATD FAMILY DEOXYRIBONUCLEASE", "d": [], "t": []}], "preferred_name": "TATD FAMILY DEOXYRIBONUCLEASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23411:SF34", "l": "T CELL RECEPTOR BETA CONSTANT 1", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA CONSTANT 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45931:SF2", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF6", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14453", "l": "PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11551:SF14", "l": "INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 6", "d": [], "t": []}], "preferred_name": "INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37345:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 107", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 107", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11958:SF20", "l": "NEUTRAL AMINO ACID TRANSPORTER A", "d": [], "t": []}], "preferred_name": "NEUTRAL AMINO ACID TRANSPORTER A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45677:SF5", "l": "GLUTAMATE DECARBOXYLASE 1", "d": [], "t": []}], "preferred_name": "GLUTAMATE DECARBOXYLASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10942", "l": "LEISHMANOLYSIN-LIKE PEPTIDASE", "d": [], "t": []}], "preferred_name": "LEISHMANOLYSIN-LIKE PEPTIDASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF78", "l": "OLFACTORY RECEPTOR 2T27-RELATED", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 2T27-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46059:SF2", "l": "BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1", "d": [], "t": []}], "preferred_name": "BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF173", "l": "OLFACTORY RECEPTOR 2T11", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 2T11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:851", "l": "Piwi-interacting RNA clusters", "d": ["Piwi-interacting RNA (piRNA) is the largest class of small non-coding RNA molecules expressed in animal cells. piRNAs form RNA-protein complexes through interactions with piwi proteins. These piRNA complexes have been linked to both epigenetic and post-transcriptional gene silencing of retrotransposons and other genetic elements in germ line cells, particularly those in spermatogenesis. They are distinct from microRNA (miRNA) in size (26-31 nt rather than 21-24 nt), lack of sequence conservation, and increased complexity.   It remains unclear how piRNAs are generated, but potential methods have been suggested, and it is certain their biogenesis pathway is distinct from miRNA and siRNA, while rasiRNAs are a piRNA subspecies."], "t": []}], "preferred_name": "Piwi-interacting RNA clusters", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1960", "l": "Coat protein complex II", "d": [], "t": []}], "preferred_name": "Coat protein complex II", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46262", "l": "FORKHEAD BOX PROTEIN BINIOU", "d": [], "t": []}], "preferred_name": "FORKHEAD BOX PROTEIN BINIOU", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2020", "l": "Type II transmembrane serine proteases", "d": [], "t": []}], "preferred_name": "Type II transmembrane serine proteases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14134", "l": "E3 UBIQUITIN-PROTEIN LIGASE RAD18", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RAD18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:981", "l": "Dynein regulatory complex", "d": [], "t": []}], "preferred_name": "Dynein regulatory complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13422:SF18", "l": "SIN3-HDAC COMPLEX-ASSOCIATED FACTOR", "d": [], "t": []}], "preferred_name": "SIN3-HDAC COMPLEX-ASSOCIATED FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24412:SF491", "l": "KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12", "d": [], "t": []}], "preferred_name": "KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 12", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45881", "l": "CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED", "d": [], "t": []}], "preferred_name": "CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45804:SF4", "l": "HOMEOBOX PROTEIN HOX-D13", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN HOX-D13", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10807:SF69", "l": "MYOTUBULARIN", "d": [], "t": []}], "preferred_name": "MYOTUBULARIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11157:SF19", "l": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1", "d": [], "t": []}], "preferred_name": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12700:SF17", "l": "ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13326", "l": "TRNA PSEUDOURIDINE SYNTHASE D", "d": [], "t": []}], "preferred_name": "TRNA PSEUDOURIDINE SYNTHASE D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12550:SF41", "l": "HEPATOMA-DERIVED GROWTH FACTOR", "d": [], "t": []}], "preferred_name": "HEPATOMA-DERIVED GROWTH FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31054:SF6", "l": "ZYGOTE ARREST PROTEIN 1", "d": [], "t": []}], "preferred_name": "ZYGOTE ARREST PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10019", "l": "SNF5", "d": [], "t": []}], "preferred_name": "SNF5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43382:SF2", "l": "BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF22", "l": "ZINC FINGER PROTEIN 317", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 317", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33590", "l": "GLUTENIN, HIGH MOLECULAR WEIGHT SUBUNIT PW212-RELATED PROTEIN", "d": [], "t": []}], "preferred_name": "GLUTENIN, HIGH MOLECULAR WEIGHT SUBUNIT PW212-RELATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43201", "l": "ACYL-COA SYNTHETASE", "d": [], "t": []}], "preferred_name": "ACYL-COA SYNTHETASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14307", "l": "C6ORF47 FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "C6ORF47 FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11736:SF60", "l": "MELANOMA-ASSOCIATED ANTIGEN 3-RELATED", "d": [], "t": []}], "preferred_name": "MELANOMA-ASSOCIATED ANTIGEN 3-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12301:SF8", "l": "STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5", "d": [], "t": []}], "preferred_name": "STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36131", "l": "KERATIN-ASSOCIATED PROTEIN 8-1", "d": [], "t": []}], "preferred_name": "KERATIN-ASSOCIATED PROTEIN 8-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10652:SF1", "l": "ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "ADENYLYL CYCLASE-ASSOCIATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46272", "l": "G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21493", "l": "CGI-141-RELATED/LIPASE CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "CGI-141-RELATED/LIPASE CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23226:SF151", "l": "ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5C", "d": [], "t": []}], "preferred_name": "ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28621:SF1", "l": "SELENOPROTEIN S", "d": [], "t": []}], "preferred_name": "SELENOPROTEIN S", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11471:SF33", "l": "TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6", "d": [], "t": []}], "preferred_name": "TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10745:SF0", "l": "GLYCINE--TRNA LIGASE", "d": [], "t": []}], "preferred_name": "GLYCINE--TRNA LIGASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16089:SF24", "l": "MITOTIC DEACETYLASE-ASSOCIATED SANT DOMAIN PROTEIN", "d": [], "t": []}], "preferred_name": "MITOTIC DEACETYLASE-ASSOCIATED SANT DOMAIN PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20856:SF8", "l": "DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2", "d": [], "t": []}], "preferred_name": "DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31626:SF1", "l": "PROTEIN FAM171A1", "d": [], "t": []}], "preferred_name": "PROTEIN FAM171A1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12411:SF270", "l": "TUBULOINTERSTITIAL NEPHRITIS ANTIGEN-LIKE", "d": [], "t": []}], "preferred_name": "TUBULOINTERSTITIAL NEPHRITIS ANTIGEN-LIKE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23245:SF36", "l": "TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22574:SF13", "l": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 1B", "d": [], "t": []}], "preferred_name": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43127:SF2", "l": "DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2", "d": [], "t": []}], "preferred_name": "DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15627:SF14", "l": "PROTEIN YIPF3", "d": [], "t": []}], "preferred_name": "PROTEIN YIPF3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16477", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 106", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 106", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10075:SF107", "l": "BASIGIN", "d": [], "t": []}], "preferred_name": "BASIGIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1306", "l": "SIN3 histone deacetylase complex subunits", "d": ["Mammalian genomes encode two homologs of SIN3 (SIN3A/B), which associate individually with HDAC1 and HDAC2, RBBP4 and RBBP7, SDS3, and the SIN3-associated proteins SAP18 and SAP30 to form the core SIN3 complex. Different studies have identified additional interaction partners including MeCP2 (methyl-CpG-binding protein), RBP1 (RB-binding protein), BRMS1 (breast cancer metastasis suppressor), ING1/2 (inhibitor of growth), SAP25, SAP130, and SAP180, as well as the histone demethylase RBP2/KDM5A (Hayakawa and Nakayama, 2011 and Kadamb et al., 2013)."], "t": []}], "preferred_name": "SIN3 histone deacetylase complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26452:SF253", "l": "OLFACTORY RECEPTOR 10Q1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 10Q1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15555:SF0", "l": "ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43172:SF1", "l": "ADENYLOSUCCINATE LYASE", "d": [], "t": []}], "preferred_name": "ADENYLOSUCCINATE LYASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21580:SF19", "l": "OUTER DENSE FIBER PROTEIN 3B", "d": [], "t": []}], "preferred_name": "OUTER DENSE FIBER PROTEIN 3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1857", "l": "Tim17 family", "d": [], "t": []}], "preferred_name": "Tim17 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11070:SF30", "l": "F-BOX DNA HELICASE 1", "d": [], "t": []}], "preferred_name": "F-BOX DNA HELICASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11780", "l": "NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1  NDUFV1", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1  NDUFV1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12010", "l": "40S RIBOSOMAL PROTEIN S29", "d": [], "t": []}], "preferred_name": "40S RIBOSOMAL PROTEIN S29", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:853", "l": "RNAs, Ro60-associated Y", "d": ["Y RNAs are small non-coding RNAs. They are components of the Ro60 ribonucleoprotein particle which is a target of autoimmune antibodies in patients with systemic lupus erythematosus."], "t": []}], "preferred_name": "RNAs, Ro60-associated Y", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:640", "l": "Mitochondrial complex I: NADH:ubiquinone oxidoreductase subunits", "d": ["Complex I ( EC 1.6.5.3 ) (also referred to as NADH:ubiquinone oxidoreductase or, especially in the context of the human protein, NADH dehydrogenase (ubiquinone) ) is an enzyme of the respiratory chains of myriad organisms from bacteria to humans. It catalyzes the transfer of electrons from NADH to coenzyme Q10 (CoQ10) and, in eukaryotes, it is located in the inner mitochondrial membrane. It is one of the 'entry enzymes' of oxidative phosphorylation in the mitochondria."], "t": []}], "preferred_name": "Mitochondrial complex I: NADH:ubiquinone oxidoreductase subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11814:SF55", "l": "SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER", "d": [], "t": []}], "preferred_name": "SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19331:SF477", "l": "T-CELL DIFFERENTIATION ANTIGEN CD6", "d": [], "t": []}], "preferred_name": "T-CELL DIFFERENTIATION ANTIGEN CD6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13382", "l": "MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:223", "l": "Bradykinin receptors", "d": ["The bradykinin receptor family is a group of G-protein coupled receptors whose principal ligand is the protein bradykinin.  There are two Bradykinin receptors: the B 1 receptor and the B 2 receptor."], "t": []}], "preferred_name": "Bradykinin receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12806:SF1", "l": "VACUOLAR-SORTING PROTEIN SNF8", "d": [], "t": []}], "preferred_name": "VACUOLAR-SORTING PROTEIN SNF8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15736", "l": "PROTEIN FAM131B-RELATED", "d": [], "t": []}], "preferred_name": "PROTEIN FAM131B-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15152:SF0", "l": "CD70 ANTIGEN", "d": [], "t": []}], "preferred_name": "CD70 ANTIGEN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22808:SF20", "l": "RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2", "d": [], "t": []}], "preferred_name": "RNA CYTOSINE C(5)-METHYLTRANSFERASE NSUN2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23311", "l": "HEAT SHOCK REGULATED 2", "d": [], "t": []}], "preferred_name": "HEAT SHOCK REGULATED 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31408:SF2", "l": "PROTEIN SPO16 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN SPO16 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12360", "l": "NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1  NFX1", "d": [], "t": []}], "preferred_name": "NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1  NFX1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21676", "l": "PROTEIN STUM", "d": [], "t": []}], "preferred_name": "PROTEIN STUM", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12832:SF14", "l": "T-COMPLEX PROTEIN 11 HOMOLOG", "d": [], "t": []}], "preferred_name": "T-COMPLEX PROTEIN 11 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31796:SF4", "l": "SUZ DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "SUZ DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24343:SF76", "l": "TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1", "d": [], "t": []}], "preferred_name": "TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31547:SF1", "l": "MULTIVESICULAR BODY SUBUNIT 12B", "d": [], "t": []}], "preferred_name": "MULTIVESICULAR BODY SUBUNIT 12B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24073:SF839", "l": "RAS-RELATED PROTEIN RAB-38", "d": [], "t": []}], "preferred_name": "RAS-RELATED PROTEIN RAB-38", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10109:SF0", "l": "MATRIX GLA PROTEIN", "d": [], "t": []}], "preferred_name": "MATRIX GLA PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10649:SF9", "l": "ARYL HYDROCARBON RECEPTOR", "d": [], "t": []}], "preferred_name": "ARYL HYDROCARBON RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13388:SF4", "l": "TRANSMEMBRANE PROTEIN 132C", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 132C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13743:SF111", "l": "NEUROBEACHIN-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "NEUROBEACHIN-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43429", "l": "PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING", "d": [], "t": []}], "preferred_name": "PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43109:SF2", "l": "NUCLEOSIDE DIPHOSPHATE KINASE 7", "d": [], "t": []}], "preferred_name": "NUCLEOSIDE DIPHOSPHATE KINASE 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14060:SF8", "l": "PROTEIN P13 MTCP-1", "d": [], "t": []}], "preferred_name": "PROTEIN P13 MTCP-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46843", "l": "BTB/POZ DOMAIN-CONTAINING PROTEIN 16", "d": [], "t": []}], "preferred_name": "BTB/POZ DOMAIN-CONTAINING PROTEIN 16", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43899", "l": "RH59310P", "d": [], "t": []}], "preferred_name": "RH59310P", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12489", "l": "LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3470", "l": "PiggyBac transposable element derived family", "d": ["Most mammalian genomes contain decayed piggyBac transposons. They ceased their activity due to several mutations or rearrangements. The human genome contains at least five domesticated piggyBac genes, designated from PGBD1 to PGBD5. On the one hand, PGBD1 and PGBD2 were probably present in the common ancestor of mammals, while PGBD3 and PGBD4 are restricted to primates. On the other hand, PGBD5, the only sequences interrupted by multiple introns, are not only orthologous in mammals and fish but also in lamprey and lancelet suggesting an ancient domestication event about 525 Ma before cephalocordates and vertebrates split from urochordates."], "t": []}], "preferred_name": "PiggyBac transposable element derived family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14386", "l": "PROTEIN FAM204A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM204A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22467:SF4", "l": "PROTEIN PBMUCL2", "d": [], "t": []}], "preferred_name": "PROTEIN PBMUCL2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11202:SF1", "l": "PROTEIN ENABLED HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN ENABLED HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43450:SF1", "l": "ASPARTATE--TRNA LIGASE, CYTOPLASMIC", "d": [], "t": []}], "preferred_name": "ASPARTATE--TRNA LIGASE, CYTOPLASMIC", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31019:SF1", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 14", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 14", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24376:SF232", "l": "ZINC FINGER PROTEIN 227", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 227", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31965:SF1", "l": "TRANSMEMBRANE PROTEIN 42", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 42", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14609:SF1", "l": "ORC UBIQUITIN LIGASE 1", "d": [], "t": []}], "preferred_name": "ORC UBIQUITIN LIGASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23327:SF4", "l": "LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1", "d": [], "t": []}], "preferred_name": "LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47980:SF22", "l": "RAS-RELATED PROTEIN RAB-3B", "d": [], "t": []}], "preferred_name": "RAS-RELATED PROTEIN RAB-3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31592", "l": "TRANSMEMBRANE PROTEIN 192", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 192", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46377", "l": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 19", "d": [], "t": []}], "preferred_name": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21101", "l": "RESISTIN", "d": [], "t": []}], "preferred_name": "RESISTIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48491", "l": "INTERLEUKIN-5", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24025:SF3", "l": "DESMOGLEIN-3", "d": [], "t": []}], "preferred_name": "DESMOGLEIN-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10807:SF66", "l": "MYOTUBULARIN-RELATED PROTEIN 3", "d": [], "t": []}], "preferred_name": "MYOTUBULARIN-RELATED PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1339", "l": "Checkpoint clamp complex", "d": [], "t": []}], "preferred_name": "Checkpoint clamp complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23102", "l": "CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED", "d": [], "t": []}], "preferred_name": "CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24280", "l": "CYTOCHROME P450 20A1", "d": [], "t": []}], "preferred_name": "CYTOCHROME P450 20A1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10201:SF143", "l": "MATRILYSIN", "d": [], "t": []}], "preferred_name": "MATRILYSIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22803:SF104", "l": "MACROPHAGE MANNOSE RECEPTOR 1", "d": [], "t": []}], "preferred_name": "MACROPHAGE MANNOSE RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21664", "l": "CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66", "d": [], "t": []}], "preferred_name": "CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48043:SF140", "l": "UDP-GLUCURONOSYLTRANSFERASE 2A1", "d": [], "t": []}], "preferred_name": "UDP-GLUCURONOSYLTRANSFERASE 2A1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11909:SF156", "l": "CASEIN KINASE I ISOFORM GAMMA-1", "d": [], "t": []}], "preferred_name": "CASEIN KINASE I ISOFORM GAMMA-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45742:SF5", "l": "COMPLEMENT COMPONENT C8 BETA CHAIN", "d": [], "t": []}], "preferred_name": "COMPLEMENT COMPONENT C8 BETA CHAIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28529", "l": "DNA REPAIR PROTEIN SWI5 HOMOLOG", "d": [], "t": []}], "preferred_name": "DNA REPAIR PROTEIN SWI5 HOMOLOG", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11690:SF128", "l": "ACID-SENSING ION CHANNEL 2", "d": [], "t": []}], "preferred_name": "ACID-SENSING ION CHANNEL 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21520", "l": "GLUTAMATE-RICH PROTEIN 2", "d": [], "t": []}], "preferred_name": "GLUTAMATE-RICH PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3657", "l": "Shu complex", "d": [], "t": []}], "preferred_name": "Shu complex", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF1000", "l": "ZINC FINGER PROTEIN 302", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 302", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11274:SF0", "l": "GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB", "d": [], "t": []}], "preferred_name": "GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24329:SF359", "l": "ALX HOMEOBOX PROTEIN 1", "d": [], "t": []}], "preferred_name": "ALX HOMEOBOX PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10545", "l": "DIAMINE N-ACETYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "DIAMINE N-ACETYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14971:SF2", "l": "VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1", "d": [], "t": []}], "preferred_name": "VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10075:SF45", "l": "CONTACTIN-6", "d": [], "t": []}], "preferred_name": "CONTACTIN-6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32086", "l": "FANCONI ANEMIA GROUP D2 PROTEIN", "d": [], "t": []}], "preferred_name": "FANCONI ANEMIA GROUP D2 PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10131:SF76", "l": "TNF RECEPTOR-ASSOCIATED FACTOR 3", "d": [], "t": []}], "preferred_name": "TNF RECEPTOR-ASSOCIATED FACTOR 3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15394", "l": "SERINE HYDROLASE RBBP9", "d": [], "t": []}], "preferred_name": "SERINE HYDROLASE RBBP9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1701", "l": "MicroRNA MIR29 family", "d": [], "t": []}], "preferred_name": "MicroRNA MIR29 family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22969:SF14", "l": "SERINE_THREONINE-PROTEIN KINASE TBK1", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE TBK1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12019:SF24", "l": "LAMINA-ASSOCIATED POLYPEPTIDE 2, ISOFORM ALPHA", "d": [], "t": []}], "preferred_name": "LAMINA-ASSOCIATED POLYPEPTIDE 2, ISOFORM ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22698", "l": "PDZ DOMAIN-CONTAINING PROTEIN 9", "d": [], "t": []}], "preferred_name": "PDZ DOMAIN-CONTAINING PROTEIN 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3463", "l": "NALCN channel complex subunits", "d": ["NALCN regulates the resting membrane potential by mediating the Na+ leak current in neurons, and it functions as a channelosome in complex with NALF1, UNC79, and UNC80. Dysfunction of the NALCN channelosome causes a broad range of neurological and developmental diseases called NALCN channelopathies in humans."], "t": []}], "preferred_name": "NALCN channel complex subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11863:SF225", "l": "METHYLSTEROL MONOOXYGENASE 1", "d": [], "t": []}], "preferred_name": "METHYLSTEROL MONOOXYGENASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13236:SF0", "l": "CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1", "d": [], "t": []}], "preferred_name": "CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35820", "l": "SPERM MITOCHONDRIAL-ASSOCIATED CYSTEINE-RICH PROTEIN", "d": [], "t": []}], "preferred_name": "SPERM MITOCHONDRIAL-ASSOCIATED CYSTEINE-RICH PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14776", "l": "CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24416:SF276", "l": "ALK TYROSINE KINASE RECEPTOR", "d": [], "t": []}], "preferred_name": "ALK TYROSINE KINASE RECEPTOR", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20968", "l": "ILGF DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "ILGF DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46161:SF1", "l": "NUCLEOSIDE DIPHOSPHATE KINASE HOMOLOG 5", "d": [], "t": []}], "preferred_name": "NUCLEOSIDE DIPHOSPHATE KINASE HOMOLOG 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15343", "l": "CD7", "d": [], "t": []}], "preferred_name": "CD7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23233", "l": "SAL-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "SAL-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11955:SF59", "l": "RETINOL-BINDING PROTEIN 2", "d": [], "t": []}], "preferred_name": "RETINOL-BINDING PROTEIN 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15207:SF1", "l": "GASDERMIN-E", "d": [], "t": []}], "preferred_name": "GASDERMIN-E", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43028:SF3", "l": "INOSITOL POLYPHOSPHATE 1-PHOSPHATASE", "d": [], "t": []}], "preferred_name": "INOSITOL POLYPHOSPHATE 1-PHOSPHATASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22115", "l": "C3ORF6 PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "C3ORF6 PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45892", "l": "AMINOACYLASE-1", "d": [], "t": []}], "preferred_name": "AMINOACYLASE-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18945:SF889", "l": "NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-10", "d": [], "t": []}], "preferred_name": "NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2297", "l": "Integrase like retrotransposon derived", "d": ["All genes in this group contain domains that are homologous to retroviral integrase proteins."], "t": []}], "preferred_name": "Integrase like retrotransposon derived", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17149", "l": "NUCLEAR PROTEIN 1 AND 2", "d": [], "t": []}], "preferred_name": "NUCLEAR PROTEIN 1 AND 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10845:SF147", "l": "REGULATOR OF G-PROTEIN SIGNALING 8", "d": [], "t": []}], "preferred_name": "REGULATOR OF G-PROTEIN SIGNALING 8", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43160", "l": "ACONITATE HYDRATASE B", "d": [], "t": []}], "preferred_name": "ACONITATE HYDRATASE B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48164:SF1", "l": "DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4", "d": [], "t": []}], "preferred_name": "DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12970:SF1", "l": "PROTEASOME ASSEMBLY CHAPERONE 2", "d": [], "t": []}], "preferred_name": "PROTEASOME ASSEMBLY CHAPERONE 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11927", "l": "GALACTOSIDE 2-L-FUCOSYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "GALACTOSIDE 2-L-FUCOSYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10534:SF2", "l": "PYRIDOXAL KINASE", "d": [], "t": []}], "preferred_name": "PYRIDOXAL KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47772", "l": "ZINC FINGER PROTEIN 200", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 200", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24073:SF343", "l": "RAS-RELATED PROTEIN RAB-6B", "d": [], "t": []}], "preferred_name": "RAS-RELATED PROTEIN RAB-6B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18916:SF44", "l": "CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1", "d": [], "t": []}], "preferred_name": "CAP-GLY DOMAIN-CONTAINING LINKER PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15298:SF9", "l": "GLYCINE N-ACYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "GLYCINE N-ACYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31543:SF0", "l": "DYNEIN REGULATORY COMPLEX SUBUNIT 4", "d": [], "t": []}], "preferred_name": "DYNEIN REGULATORY COMPLEX SUBUNIT 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24083:SF98", "l": "NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1", "d": [], "t": []}], "preferred_name": "NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10241:SF22", "l": "SYNTAXIN-BINDING PROTEIN 5", "d": [], "t": []}], "preferred_name": "SYNTAXIN-BINDING PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12352", "l": "SECRETED MODULAR CALCIUM-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "SECRETED MODULAR CALCIUM-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10464:SF6", "l": "UREA TRANSPORTER 2", "d": [], "t": []}], "preferred_name": "UREA TRANSPORTER 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12025", "l": "VASCULAR ENDOTHELIAL GROWTH FACTOR", "d": [], "t": []}], "preferred_name": "VASCULAR ENDOTHELIAL GROWTH FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13723:SF140", "l": "A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 16", "d": [], "t": []}], "preferred_name": "A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 16", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11568:SF4", "l": "HEPATOCYTE NUCLEAR FACTOR 1-ALPHA", "d": [], "t": []}], "preferred_name": "HEPATOCYTE NUCLEAR FACTOR 1-ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1644", "l": "PTK2 family tyrosine kinases", "d": [], "t": []}], "preferred_name": "PTK2 family tyrosine kinases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20859:SF51", "l": "INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-2", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-22 RECEPTOR SUBUNIT ALPHA-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31569:SF0", "l": "ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46933", "l": "MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "MYB/SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13445", "l": "TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4", "d": [], "t": []}], "preferred_name": "TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24225:SF5", "l": "G-PROTEIN COUPLED RECEPTOR 33-RELATED", "d": [], "t": []}], "preferred_name": "G-PROTEIN COUPLED RECEPTOR 33-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11258:SF4", "l": "2'-5'-OLIGOADENYLATE SYNTHASE 3", "d": [], "t": []}], "preferred_name": "2'-5'-OLIGOADENYLATE SYNTHASE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15922", "l": "NEUROBLASTOMA-AMPLIFIED SEQUENCE", "d": [], "t": []}], "preferred_name": "NEUROBLASTOMA-AMPLIFIED SEQUENCE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11918", "l": "RADICAL SAM PROTEINS", "d": [], "t": []}], "preferred_name": "RADICAL SAM PROTEINS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13037", "l": "FORMIN", "d": [], "t": []}], "preferred_name": "FORMIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28309", "l": "REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10098:SF108", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 28", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 28", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF375", "l": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-27", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-27", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21224", "l": "INTEGRATOR COMPLEX SUBUNIT 1", "d": [], "t": []}], "preferred_name": "INTEGRATOR COMPLEX SUBUNIT 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24119:SF0", "l": "ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6", "d": [], "t": []}], "preferred_name": "ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15139:SF0", "l": "TUBULIN-SPECIFIC CHAPERONE C", "d": [], "t": []}], "preferred_name": "TUBULIN-SPECIFIC CHAPERONE C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15964", "l": "APOLIPOPROTEIN B48 RECEPTOR", "d": [], "t": []}], "preferred_name": "APOLIPOPROTEIN B48 RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2028", "l": "Dynein 1 complex subunits", "d": ["Cytoplasmic dynein-1 is a major microtubule-based motor critical for cell division. Dynein is essential for the formation and positioning of the mitotic spindle as well as the transport of various cargos in the cell."], "t": []}], "preferred_name": "Dynein 1 complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3509", "l": "Protein kinase A family", "d": ["Protein kinase A (PKA) is composed of two regulatory (R) subunits forming a dimer, and two catalytic (C) subunits bound to the R subunits. Five different established or putative C subunit encoding genes have been identified in the human genome; PRKACA, PRKACB, PRKX, PRKY, and PRKACG. The PKA C subunit encoded by PRKACA was the first PK for which the 3D structure was solved and it has been extensively studied. Several structure-function-relationships encoded by PRKACA have proved to be conserved features of protein kinases (PKs) in general. The conserved catalytic core consists of an N-terminal lobe, called the small lobe or N-lobe, comprising mainly β-strands and a single α-helix. Located C-terminally is the large lobe or C-lobe, consisting mostly of α-helices. Between the small and large lobes is the active site cleft which binds an ATP molecule and two divalent cations. These cations are essential in the process of transferring the γ-phosphate of ATP to Ser or Thr residues on PKA substrates. The N- and C-terminal parts of PKs outside of the conserved catalytic core are termed the N- and C-tail, respectively. In the AGC subfamily of PKs, which includes PKA, the C-tail shares conserved features important for AGC kinase functioning, including a docking site for the AGC kinase activator PDK1. In contrast, the N-tail is highly variable even among the different PKA C subunits."], "t": []}], "preferred_name": "Protein kinase A family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10796:SF36", "l": "PATCHED DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "PATCHED DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1813", "l": "ELMO domain containing", "d": [], "t": []}], "preferred_name": "ELMO domain containing", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22576", "l": "MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE", "d": [], "t": []}], "preferred_name": "MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19443", "l": "HEXOKINASE", "d": [], "t": []}], "preferred_name": "HEXOKINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11738:SF189", "l": "IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN SUBTYPE DOMAIN-CONTAINING PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11157:SF125", "l": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6", "d": [], "t": []}], "preferred_name": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15746", "l": "RAB11-RELATED", "d": [], "t": []}], "preferred_name": "RAB11-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24242:SF90", "l": "OLFACTORY RECEPTOR 11H6", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 11H6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45635", "l": "ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED", "d": [], "t": []}], "preferred_name": "ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44427:SF1", "l": "CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1", "d": [], "t": []}], "preferred_name": "CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12653", "l": "NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3804", "l": "Hyaluronan and proteoglycan link protein family", "d": ["Hyaluronan and proteoglycan link proteins are a family of extracellular glycoproteins that help stabilize the extracellular matrix (ECM) by linking hyaluronan (HA) to Hyalectan proteoglycans (Lecticans) family members: aggrecan, versican, brevican, and neurocan."], "t": []}], "preferred_name": "Hyaluronan and proteoglycan link protein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1250", "l": "Gla domain containing", "d": [], "t": []}], "preferred_name": "Gla domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48082", "l": "ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10696", "l": "GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED", "d": [], "t": []}], "preferred_name": "GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19367:SF48", "l": "T CELL RECEPTOR ALPHA VARIABLE 9-2", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR ALPHA VARIABLE 9-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR40386:SF1", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 26", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 26", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24365:SF261", "l": "TOLL-LIKE RECEPTOR 1", "d": [], "t": []}], "preferred_name": "TOLL-LIKE RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22791:SF14", "l": "RING FINGER PROTEIN 227", "d": [], "t": []}], "preferred_name": "RING FINGER PROTEIN 227", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31699", "l": "NUDIX T16 FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "NUDIX T16 FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3770", "l": "Unc-51 like kinase family", "d": ["Serine–threonine protein kinases of the Unc-51 like kinase (ULK) family are found across eukaryotic species, with the best-characterized members found in metazoans and plants. In mammals the family has four active kinases (ULK1, ULK2, ULK3, and STK36 (Fused homolog) and one pseudokinase (ULK4). The active kinases function in multiple well-studied biological processes: ULK1 and ULK2 act in autophagy pathways in starvation responses, ULK3 is a regulator of the sonic hedgehog signaling pathway, and Fused kinase was first identified in Drosophila as a kinase of the Hedgehog (Hh) signaling pathway. Studies in the flagellated protist Leishmania mexicana show the pseudokinase ULK4 is a positive regulator of STK36 in a pathway required for stable assembly of motile cilia."], "t": []}], "preferred_name": "Unc-51 like kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23077:SF171", "l": "NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE", "d": [], "t": []}], "preferred_name": "NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11419", "l": "INTERFERON GAMMA", "d": [], "t": []}], "preferred_name": "INTERFERON GAMMA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22730:SF6", "l": "PROMININ-2", "d": [], "t": []}], "preferred_name": "PROMININ-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11801:SF18", "l": "SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA_BETA", "d": [], "t": []}], "preferred_name": "SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 1-ALPHA_BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10199", "l": "THROMBOSPONDIN", "d": [], "t": []}], "preferred_name": "THROMBOSPONDIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23253:SF10", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45883", "l": "HSC70-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "HSC70-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15586", "l": "LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1", "d": [], "t": []}], "preferred_name": "LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1471", "l": "Tetraspan junctional complex superfamily", "d": [], "t": []}], "preferred_name": "Tetraspan junctional complex superfamily", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19346:SF2", "l": "SOLUTE CARRIER FAMILY 35 MEMBER F4", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 35 MEMBER F4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15724:SF0", "l": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47646:SF1", "l": "PDZ DOMAIN-CONTAINING PROTEIN MAGIX", "d": [], "t": []}], "preferred_name": "PDZ DOMAIN-CONTAINING PROTEIN MAGIX", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10134", "l": "CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23338:SF16", "l": "U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4", "d": [], "t": []}], "preferred_name": "U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21574", "l": "CENTROSOMAL PROTEIN OF 120 KDA", "d": [], "t": []}], "preferred_name": "CENTROSOMAL PROTEIN OF 120 KDA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13202", "l": "MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT", "d": [], "t": []}], "preferred_name": "MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13059", "l": "HMG-BOX TRANSCRIPTION FACTOR BBX", "d": [], "t": []}], "preferred_name": "HMG-BOX TRANSCRIPTION FACTOR BBX", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14572:SF1", "l": "PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "PANCREATIC PROGENITOR CELL DIFFERENTIATION AND PROLIFERATION FACTOR-LIKE PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14650", "l": "PROLYL HYDROXYLASE-RELATED", "d": [], "t": []}], "preferred_name": "PROLYL HYDROXYLASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44170:SF50", "l": "ROUNDABOUT HOMOLOG 2", "d": [], "t": []}], "preferred_name": "ROUNDABOUT HOMOLOG 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10370:SF0", "l": "ERYTHROPOIETIN", "d": [], "t": []}], "preferred_name": "ERYTHROPOIETIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43550:SF3", "l": "3-KETODIHYDROSPHINGOSINE REDUCTASE", "d": [], "t": []}], "preferred_name": "3-KETODIHYDROSPHINGOSINE REDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11673:SF25", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1-LIKE", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1-LIKE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3367", "l": "7BS protein histidine methyltransferases", "d": [], "t": []}], "preferred_name": "7BS protein histidine methyltransferases", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2159", "l": "Solute carrier family 6", "d": [], "t": []}], "preferred_name": "Solute carrier family 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12411:SF929", "l": "CATHEPSIN Z", "d": [], "t": []}], "preferred_name": "CATHEPSIN Z", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22461:SF2", "l": "SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18921:SF2", "l": "THYROID RECEPTOR-INTERACTING PROTEIN 11", "d": [], "t": []}], "preferred_name": "THYROID RECEPTOR-INTERACTING PROTEIN 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31353", "l": "FAM98", "d": [], "t": []}], "preferred_name": "FAM98", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11581:SF7", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN ES4, Y ISOFORM 2", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN ES4, Y ISOFORM 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31199", "l": "ARPIN", "d": [], "t": []}], "preferred_name": "ARPIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23226:SF306", "l": "ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5B", "d": [], "t": []}], "preferred_name": "ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN 5B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12374:SF20", "l": "TRANSCRIPTIONAL ADAPTER 2-ALPHA", "d": [], "t": []}], "preferred_name": "TRANSCRIPTIONAL ADAPTER 2-ALPHA", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10502:SF18", "l": "ANNEXIN A2-RELATED", "d": [], "t": []}], "preferred_name": "ANNEXIN A2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16002:SF5", "l": "TRANSMEMBRANE PROTEIN 248", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 248", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11153:SF14", "l": "SIDEROFLEXIN-2", "d": [], "t": []}], "preferred_name": "SIDEROFLEXIN-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28680:SF1", "l": "CENTROMERE PROTEIN X", "d": [], "t": []}], "preferred_name": "CENTROMERE PROTEIN X", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3865", "l": "Muscle associated receptor tyrosine kinase family", "d": [], "t": []}], "preferred_name": "Muscle associated receptor tyrosine kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14076", "l": "RECEPTOR ACTIVITY MODIFYING PROTEIN  RAMP", "d": [], "t": []}], "preferred_name": "RECEPTOR ACTIVITY MODIFYING PROTEIN  RAMP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR38537:SF7", "l": "FILAMIN-B", "d": [], "t": []}], "preferred_name": "FILAMIN-B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10176", "l": "GLYCOGEN SYNTHASE", "d": [], "t": []}], "preferred_name": "GLYCOGEN SYNTHASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:952", "l": "SNAP complex", "d": [], "t": []}], "preferred_name": "SNAP complex", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48427:SF1", "l": "PROLINE-RICH PROTEIN 9", "d": [], "t": []}], "preferred_name": "PROLINE-RICH PROTEIN 9", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14334:SF2", "l": "B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN BETA CHAIN", "d": [], "t": []}], "preferred_name": "B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN BETA CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43602:SF1", "l": "ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21142", "l": "SARCOGLYCANS", "d": [], "t": []}], "preferred_name": "SARCOGLYCANS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12474:SF3", "l": "SESTRIN-1", "d": [], "t": []}], "preferred_name": "SESTRIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23087", "l": "NONHISTONE CHROMOSOMAL PROTEIN HMG", "d": [], "t": []}], "preferred_name": "NONHISTONE CHROMOSOMAL PROTEIN HMG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19924", "l": "UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33517:SF3", "l": "PROTEIN FAM170A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM170A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18966:SF38", "l": "GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2", "d": [], "t": []}], "preferred_name": "GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13174", "l": "D-GLUCURONYL C5-EPIMERASE", "d": [], "t": []}], "preferred_name": "D-GLUCURONYL C5-EPIMERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12247:SF128", "l": "SEX COMB ON MIDLEG-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "SEX COMB ON MIDLEG-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12659", "l": "RHO-TYPE GTPASE ACTIVATING PROTEIN", "d": [], "t": []}], "preferred_name": "RHO-TYPE GTPASE ACTIVATING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10779", "l": "DYNEIN LIGHT CHAIN ROADBLOCK", "d": [], "t": []}], "preferred_name": "DYNEIN LIGHT CHAIN ROADBLOCK", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19143:SF263", "l": "FIBRINOGEN-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "FIBRINOGEN-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16263:SF4", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 38", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 38", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13449:SF2", "l": "PROTEIN WNTLESS HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN WNTLESS HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47415:SF2", "l": "PROTEIN FAM47C-RELATED", "d": [], "t": []}], "preferred_name": "PROTEIN FAM47C-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12830", "l": "ANAPHASE-PROMOTING COMPLEX SUBUNIT 5", "d": [], "t": []}], "preferred_name": "ANAPHASE-PROMOTING COMPLEX SUBUNIT 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10424:SF68", "l": "ENDOGENOUS RETROVIRUS GROUP 3 MEMBER 1 ENV POLYPROTEIN", "d": [], "t": []}], "preferred_name": "ENDOGENOUS RETROVIRUS GROUP 3 MEMBER 1 ENV POLYPROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12881", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11632", "l": "SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT", "d": [], "t": []}], "preferred_name": "SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10656:SF8", "l": "INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR-INTERACTING PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21257", "l": "DELTA(14)-STEROL REDUCTASE", "d": [], "t": []}], "preferred_name": "DELTA(14)-STEROL REDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15075:SF5", "l": "ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A", "d": [], "t": []}], "preferred_name": "ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19433:SF52", "l": "T CELL RECEPTOR ALPHA VARIABLE 21", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR ALPHA VARIABLE 21", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17920:SF3", "l": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12035:SF111", "l": "SIALIC ACID-BINDING IG-LIKE LECTIN 7", "d": [], "t": []}], "preferred_name": "SIALIC ACID-BINDING IG-LIKE LECTIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10082:SF15", "l": "INTEGRIN BETA-2", "d": [], "t": []}], "preferred_name": "INTEGRIN BETA-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47110:SF2", "l": "UROPLAKIN-1B", "d": [], "t": []}], "preferred_name": "UROPLAKIN-1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11214:SF23", "l": "N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3", "d": [], "t": []}], "preferred_name": "N-ACETYLLACTOSAMINIDE BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE 3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23306:SF17", "l": "TUMOR SUSCEPTIBILITY GENE 101 PROTEIN", "d": [], "t": []}], "preferred_name": "TUMOR SUSCEPTIBILITY GENE 101 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12268", "l": "E3 UBIQUITIN-PROTEIN LIGASE KCMF1", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE KCMF1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10050:SF51", "l": "PROTEIN O-MANNOSYL-TRANSFERASE 1", "d": [], "t": []}], "preferred_name": "PROTEIN O-MANNOSYL-TRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37359", "l": "TRANSMEMBRANE PROTEIN 253", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 253", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11860:SF101", "l": "CMRF35-LIKE MOLECULE 1", "d": [], "t": []}], "preferred_name": "CMRF35-LIKE MOLECULE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13633", "l": "MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47634", "l": "PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12612:SF4", "l": "NTF2-RELATED EXPORT PROTEIN 1", "d": [], "t": []}], "preferred_name": "NTF2-RELATED EXPORT PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21183", "l": "RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED", "d": [], "t": []}], "preferred_name": "RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13237", "l": "SOMETHING ABOUT SILENCING PROTEIN 10-RELATED", "d": [], "t": []}], "preferred_name": "SOMETHING ABOUT SILENCING PROTEIN 10-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19237:SF21", "l": "NUCLEOBINDIN-1", "d": [], "t": []}], "preferred_name": "NUCLEOBINDIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2069", "l": "Retinoic acid receptors", "d": [], "t": []}], "preferred_name": "Retinoic acid receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11481:SF12", "l": "HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11706:SF40", "l": "NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2", "d": [], "t": []}], "preferred_name": "NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23322", "l": "FAS-ASSOCIATED PROTEIN", "d": [], "t": []}], "preferred_name": "FAS-ASSOCIATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46260:SF1", "l": "KELCH DOMAIN-CONTAINING PROTEIN 8A", "d": [], "t": []}], "preferred_name": "KELCH DOMAIN-CONTAINING PROTEIN 8A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15299:SF3", "l": "HERV-H LTR-ASSOCIATING PROTEIN 1", "d": [], "t": []}], "preferred_name": "HERV-H LTR-ASSOCIATING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11523:SF47", "l": "SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3", "d": [], "t": []}], "preferred_name": "SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10510:SF15", "l": "CYTOCHROME C OXIDASE SUBUNIT 7A2, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "CYTOCHROME C OXIDASE SUBUNIT 7A2, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19877:SF1", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14112:SF8", "l": "PROTEIN SSX4", "d": [], "t": []}], "preferred_name": "PROTEIN SSX4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46794:SF2", "l": "AMELOGENIN, X ISOFORM", "d": [], "t": []}], "preferred_name": "AMELOGENIN, X ISOFORM", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14343:SF3", "l": "SIMILAR TO PREDICTED GENE ICRFP703B1614Q5.5", "d": [], "t": []}], "preferred_name": "SIMILAR TO PREDICTED GENE ICRFP703B1614Q5.5", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12497:SF0", "l": "TAFAZZIN", "d": [], "t": []}], "preferred_name": "TAFAZZIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12083", "l": "BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31977", "l": "UPF0696 PROTEIN C11ORF68", "d": [], "t": []}], "preferred_name": "UPF0696 PROTEIN C11ORF68", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11199", "l": "STROMAL ANTIGEN", "d": [], "t": []}], "preferred_name": "STROMAL ANTIGEN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13832:SF533", "l": "TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24343:SF133", "l": "NUAK FAMILY SNF1-LIKE KINASE 2", "d": [], "t": []}], "preferred_name": "NUAK FAMILY SNF1-LIKE KINASE 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12121:SF27", "l": "PROTEIN ANGEL HOMOLOG 2", "d": [], "t": []}], "preferred_name": "PROTEIN ANGEL HOMOLOG 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24200:SF6", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 69", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 69", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461", "l": "SERINE PROTEASE INHIBITOR, SERPIN", "d": [], "t": []}], "preferred_name": "SERINE PROTEASE INHIBITOR, SERPIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1419", "l": "m6A methyltransferase complex", "d": ["N6-methyladenosine modification in mRNA influences mRNA splicing, export, localization, translation, and stability. The m6A writer complex is located in the nuclear speckle, and catalyses the transfer of methyl groups from S-adenosylmethionine (SAM) to the specific adenines on the target RNAs. METTL3 and METTL14 are the catalytic subunits in this complex."], "t": []}], "preferred_name": "m6A methyltransferase complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10822:SF25", "l": "GLYPICAN-4", "d": [], "t": []}], "preferred_name": "GLYPICAN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11937:SF175", "l": "ACTIN-RELATED PROTEIN 3", "d": [], "t": []}], "preferred_name": "ACTIN-RELATED PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37341:SF1", "l": "PROTEIN INCA1", "d": [], "t": []}], "preferred_name": "PROTEIN INCA1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45616:SF31", "l": "KERATIN, TYPE II CYTOSKELETAL 73", "d": [], "t": []}], "preferred_name": "KERATIN, TYPE II CYTOSKELETAL 73", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22779", "l": "SD17342P", "d": [], "t": []}], "preferred_name": "SD17342P", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10036:SF24", "l": "CD59 GLYCOPROTEIN", "d": [], "t": []}], "preferred_name": "CD59 GLYCOPROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15004", "l": "GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11394", "l": "TASTE RECEPTOR TYPE 2", "d": [], "t": []}], "preferred_name": "TASTE RECEPTOR TYPE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23152", "l": "2-OXOGLUTARATE DEHYDROGENASE", "d": [], "t": []}], "preferred_name": "2-OXOGLUTARATE DEHYDROGENASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11749:SF19", "l": "RIBULOSE-PHOSPHATE 3-EPIMERASE-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "RIBULOSE-PHOSPHATE 3-EPIMERASE-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1398", "l": "Methyltransferase families", "d": ["Please note, there are overlaps between the methyltransferase 'sorted by structure' and 'sorted by function' groupings. All methyltransferase group members are represented in the structural hierarchy."], "t": []}], "preferred_name": "Methyltransferase families", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14699:SF1", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 21B", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 21B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43205", "l": "PROSTAGLANDIN REDUCTASE", "d": [], "t": []}], "preferred_name": "PROSTAGLANDIN REDUCTASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39412", "l": "TESTIS-EXPRESSED PROTEIN 46", "d": [], "t": []}], "preferred_name": "TESTIS-EXPRESSED PROTEIN 46", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31120:SF8", "l": "METALLOPROTEASE TIKI2", "d": [], "t": []}], "preferred_name": "METALLOPROTEASE TIKI2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36134:SF1", "l": "TRANSMEMBRANE PROTEIN C16ORF54", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN C16ORF54", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15507:SF18", "l": "ZINC FINGER PROTEIN RLF", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN RLF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24381:SF76", "l": "ZINC FINGER PROTEIN 891", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 891", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10067:SF6", "l": "PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23149:SF27", "l": "PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1", "d": [], "t": []}], "preferred_name": "PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15462:SF17", "l": "INACTIVE SERINE PROTEASE 35", "d": [], "t": []}], "preferred_name": "INACTIVE SERINE PROTEASE 35", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10338:SF115", "l": "INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3", "d": [], "t": []}], "preferred_name": "INTER-ALPHA-TRYPSIN INHIBITOR HEAVY CHAIN H3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR38500", "l": "SURFACTANT-ASSOCIATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "SURFACTANT-ASSOCIATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23349:SF5", "l": "BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR SCLERAXIS", "d": [], "t": []}], "preferred_name": "BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR SCLERAXIS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3512", "l": "HUSH complex", "d": ["Mediates epigenetic repression, responsible for position-effect variegation of integrated transgenes in human cells. Recruited to genomic loci rich in H3K9me3, where subsequent recruitment of the histone methyltransferase SETDB1 (Q15047) is required for further H3K9me3 deposition to maintain transcriptional silencing. Acts with MORC2 (Q9Y6X9) to repress LINE-1 class I transposable elements."], "t": []}], "preferred_name": "HUSH complex", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18934:SF213", "l": "3'-5' RNA HELICASE YTHDC2", "d": [], "t": []}], "preferred_name": "3'-5' RNA HELICASE YTHDC2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15076:SF15", "l": "CD99 ANTIGEN", "d": [], "t": []}], "preferred_name": "CD99 ANTIGEN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1269", "l": "Nucleotide excision repair", "d": [], "t": []}], "preferred_name": "Nucleotide excision repair", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45973:SF2", "l": "CENTROSOMAL PROTEIN OF 97 KDA", "d": [], "t": []}], "preferred_name": "CENTROSOMAL PROTEIN OF 97 KDA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16255:SF1", "l": "REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG", "d": [], "t": []}], "preferred_name": "REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23073", "l": "26S PROTEASOME REGULATORY SUBUNIT", "d": [], "t": []}], "preferred_name": "26S PROTEASOME REGULATORY SUBUNIT", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34994", "l": "PROTEIN FAM25A-RELATED", "d": [], "t": []}], "preferred_name": "PROTEIN FAM25A-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48021:SF18", "l": "SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 8", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 8", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15739", "l": "ZINC FINGER PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24384:SF211", "l": "ZINC FINGER PROTEIN 138-RELATED", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 138-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11596:SF74", "l": "ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME", "d": [], "t": []}], "preferred_name": "ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC ISOZYME", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10204", "l": "NAD P H OXIDOREDUCTASE-RELATED", "d": [], "t": []}], "preferred_name": "NAD P H OXIDOREDUCTASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12900:SF4", "l": "CHECKPOINT PROTEIN HUS1", "d": [], "t": []}], "preferred_name": "CHECKPOINT PROTEIN HUS1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13113", "l": "ECSIT  EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS", "d": [], "t": []}], "preferred_name": "ECSIT  EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:405", "l": "Apolipoproteins", "d": ["Protein or apolipoprotein associated with High-Density Lipoproteins (HDL), a class of proteins involved in lipid (cholesterol, phospholipids and triacylglycerol) metabolism in the body fluids. HDL are formed in the liver and are involved in reverse cholesterol transport, the transport of cholesterol from peripherical tissues to the liver. Apolipoproteins are proteins which are specifically associated with lipoproteins, which is not the case for all the proteins associated with HDL or with the other lipoprotein classes."], "t": []}], "preferred_name": "Apolipoproteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19237:SF22", "l": "NUCLEOBINDIN-2", "d": [], "t": []}], "preferred_name": "NUCLEOBINDIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12901", "l": "SPERM PROTEIN HOMOLOG", "d": [], "t": []}], "preferred_name": "SPERM PROTEIN HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11662:SF29", "l": "VESICULAR GLUTAMATE TRANSPORTER 1", "d": [], "t": []}], "preferred_name": "VESICULAR GLUTAMATE TRANSPORTER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11027", "l": "APOLIPOPROTEIN A-II", "d": [], "t": []}], "preferred_name": "APOLIPOPROTEIN A-II", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11036:SF11", "l": "SEMAPHORIN-6C", "d": [], "t": []}], "preferred_name": "SEMAPHORIN-6C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47010", "l": "CYSTATIN-8-RELATED", "d": [], "t": []}], "preferred_name": "CYSTATIN-8-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19303:SF11", "l": "JERKY PROTEIN HOMOLOG", "d": [], "t": []}], "preferred_name": "JERKY PROTEIN HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31831", "l": "HYPOTHETICAL PROTEIN LOC689065", "d": [], "t": []}], "preferred_name": "HYPOTHETICAL PROTEIN LOC689065", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11223", "l": "EXPORTIN 1/5", "d": [], "t": []}], "preferred_name": "EXPORTIN 1/5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20916:SF26", "l": "CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "CYSTEINE-RICH PROTEIN 2-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34768:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 89", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 89", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3659", "l": "Pyruvate kinase family", "d": ["In human, two distinct genes encode PK enzymes [EC:2.7.1.40] pyruvate kinase M (PKM) and pyruvate kinase L/R (PKLR). The PKM gene encodes for PK-M1 (muscle) and PK-M2 (fetal) isoenzymes by alternative splicing. PKLR codes for both the PK-L (Liver-type) and PK-R (Red Blood Cells-Type) isoenzymes using two alternative promoters."], "t": []}], "preferred_name": "Pyruvate kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24072:SF21", "l": "RHO-RELATED GTP-BINDING PROTEIN RHON", "d": [], "t": []}], "preferred_name": "RHO-RELATED GTP-BINDING PROTEIN RHON", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3624", "l": "Rab geranylgeranyltransferase subunits", "d": ["Rab proteins comprise a family of small GTPases that serve a regulatory role in vesicular membrane traffic. Geranylgeranylation of these proteins on C-terminal cysteine motifs is crucial for their membrane association and function. This post-translational modification is catalysed by rab geranylgeranyl transferase (Rab-GGTase), a multisubunit enzyme consisting of a catalytic heterodimer of alpha and beta subunits and a substrate binding subunit encoded CHM or CHML (also known as REP-1 and REP-2)."], "t": []}], "preferred_name": "Rab geranylgeranyltransferase subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11036:SF39", "l": "SEMAPHORIN-5B", "d": [], "t": []}], "preferred_name": "SEMAPHORIN-5B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46674:SF1", "l": "INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6", "d": [], "t": []}], "preferred_name": "INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:588", "l": "Histocompatibility complex", "d": ["The major histocompatibility complex ( MHC ) is a set of cell surface molecules encoded by a large gene family in all vertebrates. MHC molecules mediate interactions of leukocytes, also called white blood cells (WBCs), which are immune cells, with other leukocytes or body cells. MHC determines compatibility of donors for organ transplant as well as one's susceptibility to an autoimmune disease via crossreacting immunization."], "t": []}], "preferred_name": "Histocompatibility complex", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47615:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 158", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 158", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11616:SF105", "l": "SODIUM-DEPENDENT SEROTONIN TRANSPORTER", "d": [], "t": []}], "preferred_name": "SODIUM-DEPENDENT SEROTONIN TRANSPORTER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35975", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 11A", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 11A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15444", "l": "SECRETED PHOSPHOPROTEIN 24", "d": [], "t": []}], "preferred_name": "SECRETED PHOSPHOPROTEIN 24", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14198:SF18", "l": "TRANSMEMBRANE 4 L6 FAMILY MEMBER 1", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE 4 L6 FAMILY MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23084", "l": "PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23316:SF11", "l": "IMPORTIN SUBUNIT ALPHA-8", "d": [], "t": []}], "preferred_name": "IMPORTIN SUBUNIT ALPHA-8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12752:SF4", "l": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7", "d": [], "t": []}], "preferred_name": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 7", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15532:SF3", "l": "DERMATAN-SULFATE EPIMERASE", "d": [], "t": []}], "preferred_name": "DERMATAN-SULFATE EPIMERASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23319:SF3", "l": "PROTEIN ASTER-B", "d": [], "t": []}], "preferred_name": "PROTEIN ASTER-B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24020:SF23", "l": "VITRIN", "d": [], "t": []}], "preferred_name": "VITRIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12290:SF10", "l": "PROTEIN CORNICHON HOMOLOG 1", "d": [], "t": []}], "preferred_name": "PROTEIN CORNICHON HOMOLOG 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31586:SF2", "l": "CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19964", "l": "MULTIPLE PDZ DOMAIN PROTEIN", "d": [], "t": []}], "preferred_name": "MULTIPLE PDZ DOMAIN PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14186:SF16", "l": "INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-LIKE 1", "d": [], "t": []}], "preferred_name": "INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-LIKE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11348:SF8", "l": "CCN FAMILY MEMBER 3", "d": [], "t": []}], "preferred_name": "CCN FAMILY MEMBER 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46727", "l": "E3 SUMO-PROTEIN LIGASE CBX4", "d": [], "t": []}], "preferred_name": "E3 SUMO-PROTEIN LIGASE CBX4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13619", "l": "PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23430:SF378", "l": "HISTONE H2A TYPE 1-J", "d": [], "t": []}], "preferred_name": "HISTONE H2A TYPE 1-J", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43128:SF9", "l": "L-LACTATE DEHYDROGENASE A-LIKE 6A", "d": [], "t": []}], "preferred_name": "L-LACTATE DEHYDROGENASE A-LIKE 6A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19932", "l": "WD REPEAT AND HMG-BOX DNA BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "WD REPEAT AND HMG-BOX DNA BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48001:SF69", "l": "OLFACTORY RECEPTOR 1F12P-RELATED", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 1F12P-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11348:SF18", "l": "CCN FAMILY MEMBER 1", "d": [], "t": []}], "preferred_name": "CCN FAMILY MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47115:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 183", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 183", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47641:SF1", "l": "GOLGI-ASSOCIATED OLFACTORY SIGNALING REGULATOR", "d": [], "t": []}], "preferred_name": "GOLGI-ASSOCIATED OLFACTORY SIGNALING REGULATOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16026", "l": "CARTILAGE ACIDIC PROTEIN 1", "d": [], "t": []}], "preferred_name": "CARTILAGE ACIDIC PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12801:SF82", "l": "RNA EXONUCLEASE 5", "d": [], "t": []}], "preferred_name": "RNA EXONUCLEASE 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13019:SF23", "l": "GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG C", "d": [], "t": []}], "preferred_name": "GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13071", "l": "MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10281:SF23", "l": "MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 1", "d": [], "t": []}], "preferred_name": "MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10132", "l": "ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14139:SF3", "l": "CALSYNTENIN-2", "d": [], "t": []}], "preferred_name": "CALSYNTENIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24416:SF134", "l": "INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1", "d": [], "t": []}], "preferred_name": "INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15653:SF1", "l": "STRIATIN-4", "d": [], "t": []}], "preferred_name": "STRIATIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46875", "l": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5", "d": [], "t": []}], "preferred_name": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45589", "l": "WD REPEAT DOMAIN 62, ISOFORM G", "d": [], "t": []}], "preferred_name": "WD REPEAT DOMAIN 62, ISOFORM G", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42808:SF3", "l": "HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11309:SF45", "l": "SECRETED FRIZZLED-RELATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "SECRETED FRIZZLED-RELATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23215:SF0", "l": "BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207", "d": [], "t": []}], "preferred_name": "BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24399", "l": "ZINC FINGER AND BTB DOMAIN-CONTAINING", "d": [], "t": []}], "preferred_name": "ZINC FINGER AND BTB DOMAIN-CONTAINING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11242:SF14", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 9C", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 9C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13707:SF30", "l": "SUCCINYL-COA:3-KETOACID COENZYME A TRANSFERASE 1, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "SUCCINYL-COA:3-KETOACID COENZYME A TRANSFERASE 1, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22881:SF12", "l": "BROMODOMAIN-CONTAINING PROTEIN 7", "d": [], "t": []}], "preferred_name": "BROMODOMAIN-CONTAINING PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13078", "l": "PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED", "d": [], "t": []}], "preferred_name": "PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47046:SF1", "l": "SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 1, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12611:SF3", "l": "PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA", "d": [], "t": []}], "preferred_name": "PURINE-RICH ELEMENT-BINDING PROTEIN GAMMA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10844", "l": "CAVEOLIN", "d": [], "t": []}], "preferred_name": "CAVEOLIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23226", "l": "ZINC FINGER AND SCAN DOMAIN-CONTAINING", "d": [], "t": []}], "preferred_name": "ZINC FINGER AND SCAN DOMAIN-CONTAINING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10340", "l": "SPHINGOMYELIN PHOSPHODIESTERASE", "d": [], "t": []}], "preferred_name": "SPHINGOMYELIN PHOSPHODIESTERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45627:SF11", "l": "ADENYLATE CYCLASE TYPE 6", "d": [], "t": []}], "preferred_name": "ADENYLATE CYCLASE TYPE 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46536", "l": "ARL14 EFFECTOR PROTEIN", "d": [], "t": []}], "preferred_name": "ARL14 EFFECTOR PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47509:SF1", "l": "RIKEN CDNA 4933402N03 GENE", "d": [], "t": []}], "preferred_name": "RIKEN CDNA 4933402N03 GENE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10780:SF20", "l": "MITOCHONDRIAL CARRIER HOMOLOG 2", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL CARRIER HOMOLOG 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:967", "l": "Cystatins, type 3", "d": [], "t": []}], "preferred_name": "Cystatins, type 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46252:SF4", "l": "BRORIN", "d": [], "t": []}], "preferred_name": "BRORIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10362:SF7", "l": "HISTIDINE AMMONIA-LYASE", "d": [], "t": []}], "preferred_name": "HISTIDINE AMMONIA-LYASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37154", "l": "MITOREGULIN", "d": [], "t": []}], "preferred_name": "MITOREGULIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1745", "l": "General transcription factor IIH complex subunits", "d": ["Transcription factor II Human (Transcription Factor II H; TFIIH) is an important protein complex, having roles in transcription of various protein-coding genes and DNA nucleotide excision repair (NER) pathways. TFIIH first came to light in 1989 when general transcription factor-δ or basic transcription factor 2 was characterized as an indispensable transcription factor in vitro. This factor was also isolated from yeast and finally named as TFIIH in 1992.TFIIH consists of ten subunits, 7 of which (ERCC2/XPD, ERCC3/XPB, GTF2H1/p62, GTF2H4/p52, GTF2H2/p44, GTF2H3/p34 and GTF2H5/TTDA) form the core complex. The cyclin activating kinase-subcomplex (CDK7, MAT1, and cyclin H) is linked to the core via the XPD protein Two of the subunits, ERCC2/XPD and ERCC3/XPB, have helicase and ATPase activities and help create the transcription bubble. In a test tube these subunits are only required for transcription if the DNA template is not already denatured or if it is supercoiled.  Two other TFIIH subunits, CDK7 and cyclin H, phosphorylate serine amino acids on the RNA polymerase II C-terminal domain and possibly other proteins involved in the cell cycle. Next to a vital function in transcription initiation, TFIIH is also involved in nucleotide excision repair."], "t": []}], "preferred_name": "General transcription factor IIH complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1507", "l": "Spliceosomal B complex", "d": ["The spliceosomal B complex is an intermediate complex in the assembly of a spliceosome.    The <a href='/data/genegroup/#!/group/1504' target='_blank'>spliceosomal A complex</a> associates with the U4/U6.U5 tri-snRNP to generate the B complex. The B complex remains catalytically inactive until it undergoes extensive compositional and conformational rearrangements, including the dissociation of U1 and U4, resulting in the formation of the <a href='https://www.genenames.org/data/genegroup/#!/group/1508'>Bact complex</a>. This is converted into a catalytically active spliceosome (designated B*) by the action of the RNA helicase DHX16. The B* complex catalyses the first step of splicing, generating the cleaved 5' exon and intron-3' exon lariat intermediates and forming the <a href='https://www.genenames.org/data/genegroup/#!/group/1510'>C complex</a>."], "t": []}], "preferred_name": "Spliceosomal B complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1528", "l": "Ribosomal 45S rRNA genes outside of clusters", "d": ["These 45S pre-ribosomal RNA genes, and the 18S, 28S and 5.8S rRNA which may be processed from each 45S rRNA shown below, are found outside of the 13p12, 14p12, 15p12, 21p12 and 22p12 rRNA clusters that are the sites of rRNA transcription in the nucleolus. Therefore it is not certain whether these genes would be transcribed into functional rRNA molecules. To denote this, each gene symbol has the letter 'N' before its numerical identifier."], "t": []}], "preferred_name": "Ribosomal 45S rRNA genes outside of clusters", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22654", "l": "G PROTEIN PATHWAY SUPPRESSOR 2", "d": [], "t": []}], "preferred_name": "G PROTEIN PATHWAY SUPPRESSOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46218", "l": "LASP", "d": [], "t": []}], "preferred_name": "LASP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF460", "l": "IMMUNOGLOBULIN KAPPA VARIABLE 1D-16", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN KAPPA VARIABLE 1D-16", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23324:SF41", "l": "SEC14-LIKE PROTEIN 6-RELATED", "d": [], "t": []}], "preferred_name": "SEC14-LIKE PROTEIN 6-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16209:SF3", "l": "PROLINE-RICH PROTEIN 7", "d": [], "t": []}], "preferred_name": "PROLINE-RICH PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1845", "l": "GAGE family", "d": [], "t": []}], "preferred_name": "GAGE family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13906:SF16", "l": "LYSOPHOSPHOLIPID ACYLTRANSFERASE 7", "d": [], "t": []}], "preferred_name": "LYSOPHOSPHOLIPID ACYLTRANSFERASE 7", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34930", "l": "GEO05313P1", "d": [], "t": []}], "preferred_name": "GEO05313P1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18863", "l": "TSEC-2-RELATED", "d": [], "t": []}], "preferred_name": "TSEC-2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10704:SF36", "l": "CARBOHYDRATE SULFOTRANSFERASE 1", "d": [], "t": []}], "preferred_name": "CARBOHYDRATE SULFOTRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11683:SF11", "l": "MYELIN PROTEOLIPID PROTEIN", "d": [], "t": []}], "preferred_name": "MYELIN PROTEOLIPID PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45857:SF3", "l": "FORMIN-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "FORMIN-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13544", "l": "SELENOPROTEIN T", "d": [], "t": []}], "preferred_name": "SELENOPROTEIN T", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14027", "l": "RNA POLYMERASE-ASSOCIATED PROTEIN CTR9", "d": [], "t": []}], "preferred_name": "RNA POLYMERASE-ASSOCIATED PROTEIN CTR9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF853", "l": "ZINC FINGER PROTEIN 888", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 888", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15361", "l": "RAD51/NUKS-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "RAD51/NUKS-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35084", "l": "TCF3 FUSION PARTNER", "d": [], "t": []}], "preferred_name": "TCF3 FUSION PARTNER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15090:SF0", "l": "SEQUESTOSOME-1", "d": [], "t": []}], "preferred_name": "SEQUESTOSOME-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR38650:SF1", "l": "KITA-KYUSHU LUNG CANCER ANTIGEN 1", "d": [], "t": []}], "preferred_name": "KITA-KYUSHU LUNG CANCER ANTIGEN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18820:SF1", "l": "PROTEIN LEG1 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN LEG1 HOMOLOG", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21964", "l": "BREAST CANCER METASTASIS-SUPPRESSOR 1", "d": [], "t": []}], "preferred_name": "BREAST CANCER METASTASIS-SUPPRESSOR 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16566", "l": "APOLIPOPROTEIN C-II", "d": [], "t": []}], "preferred_name": "APOLIPOPROTEIN C-II", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47051:SF1", "l": "NESTIN", "d": [], "t": []}], "preferred_name": "NESTIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17097:SF0", "l": "NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C1, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C1, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10166", "l": "VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED", "d": [], "t": []}], "preferred_name": "VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24323:SF3", "l": "VISUAL SYSTEM HOMEOBOX 1", "d": [], "t": []}], "preferred_name": "VISUAL SYSTEM HOMEOBOX 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23343", "l": "ZONA PELLUCIDA SPERM-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "ZONA PELLUCIDA SPERM-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18884:SF71", "l": "SEPTIN-4", "d": [], "t": []}], "preferred_name": "SEPTIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14167:SF28", "l": "SH3 DOMAIN-CONTAINING PROTEIN 21", "d": [], "t": []}], "preferred_name": "SH3 DOMAIN-CONTAINING PROTEIN 21", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43690:SF18", "l": "INSULIN-DEGRADING ENZYME-RELATED", "d": [], "t": []}], "preferred_name": "INSULIN-DEGRADING ENZYME-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10812:SF13", "l": "TRANSCRIPTION FACTOR AP-2-EPSILON", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR AP-2-EPSILON", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12346:SF2", "l": "PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A", "d": [], "t": []}], "preferred_name": "PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47966:SF42", "l": "CATHEPSIN D", "d": [], "t": []}], "preferred_name": "CATHEPSIN D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15893:SF0", "l": "LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M", "d": [], "t": []}], "preferred_name": "LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12974:SF25", "l": "TERMINAL NUCLEOTIDYLTRANSFERASE 5A", "d": [], "t": []}], "preferred_name": "TERMINAL NUCLEOTIDYLTRANSFERASE 5A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10352:SF10", "l": "CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN TIA1", "d": [], "t": []}], "preferred_name": "CYTOTOXIC GRANULE ASSOCIATED RNA BINDING PROTEIN TIA1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3886", "l": "GRB10 interacting GYF protein family", "d": [], "t": []}], "preferred_name": "GRB10 interacting GYF protein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12675:SF3", "l": "MUSCLEBLIND-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "MUSCLEBLIND-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24023:SF539", "l": "COLLAGEN ALPHA-2(V) CHAIN", "d": [], "t": []}], "preferred_name": "COLLAGEN ALPHA-2(V) CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF98", "l": "PROTOCADHERIN BETA-18-RELATED", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN BETA-18-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11950:SF43", "l": "RUNT-RELATED TRANSCRIPTION FACTOR 3", "d": [], "t": []}], "preferred_name": "RUNT-RELATED TRANSCRIPTION FACTOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23040", "l": "FAMILY NOT NAMED", "d": [], "t": []}], "preferred_name": "FAMILY NOT NAMED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16308", "l": "UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER", "d": [], "t": []}], "preferred_name": "UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32343", "l": "SERINE/ARGININE-RICH SPLICING FACTOR", "d": [], "t": []}], "preferred_name": "SERINE/ARGININE-RICH SPLICING FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33768:SF5", "l": "SPERM AXONEMAL MAINTENANCE PROTEIN CFAP97D1", "d": [], "t": []}], "preferred_name": "SPERM AXONEMAL MAINTENANCE PROTEIN CFAP97D1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15653", "l": "STRIATIN", "d": [], "t": []}], "preferred_name": "STRIATIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11523:SF10", "l": "SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1", "d": [], "t": []}], "preferred_name": "SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32001:SF1", "l": "KERATINOCYTE-ASSOCIATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "KERATINOCYTE-ASSOCIATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23262:SF71", "l": "KERATIN-ASSOCIATED PROTEIN 4-5", "d": [], "t": []}], "preferred_name": "KERATIN-ASSOCIATED PROTEIN 4-5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23280:SF15", "l": "BAND 4.1-LIKE PROTEIN 5", "d": [], "t": []}], "preferred_name": "BAND 4.1-LIKE PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48018:SF28", "l": "OLFACTORY RECEPTOR 8K3", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 8K3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24373:SF130", "l": "LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 3", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT AND IMMUNOGLOBULIN-LIKE DOMAIN-CONTAINING NOGO RECEPTOR-INTERACTING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11834:SF2", "l": "TRANSCRIPTIONAL ENHANCER FACTOR TEF-3", "d": [], "t": []}], "preferred_name": "TRANSCRIPTIONAL ENHANCER FACTOR TEF-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35818", "l": "C1ORF189", "d": [], "t": []}], "preferred_name": "C1ORF189", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21462:SF4", "l": "CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1", "d": [], "t": []}], "preferred_name": "CELL SURFACE GLYCOPROTEIN CD200 RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13555:SF67", "l": "ZINC FINGER PROTEIN 474", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 474", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46212", "l": "PEFLIN", "d": [], "t": []}], "preferred_name": "PEFLIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1194", "l": "Mannosidases alpha class 2", "d": ["Glycoside hydrolases of family 38 are Class II α-mannosidases. They range in breadth of specificity from the Golgi α-mannosidase (2A1), which has a dual specificity for α-1,6 and α-1,3-linked mannoses, to the lysosomal mannosidases, which have either broad (2B1 cleaves α1,2, α1,3 and α1,6 linkages) or narrow specificities (2B2 is specific for α-1,6). There have been GH38 mannosidases identified in a number of different localizations, classed into subfamilies with different substrate specificities and biochemical properties, and, presumably, different physiological roles. The Golgi enzyme is identified as 2A1 (Class 2, A for Golgi, enzyme 1). Lysosomal GH38 mannosidases are indicated by 'B' (2B1, 2B2) and those likely existing in the cytoplasm by 'C'."], "t": []}], "preferred_name": "Mannosidases alpha class 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1485", "l": "U3 small nucleolar ribonucleoprotein", "d": [], "t": []}], "preferred_name": "U3 small nucleolar ribonucleoprotein", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12129:SF15", "l": "URONYL 2-SULFOTRANSFERASE", "d": [], "t": []}], "preferred_name": "URONYL 2-SULFOTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14889", "l": "RCG36411", "d": [], "t": []}], "preferred_name": "RCG36411", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22722:SF11", "l": "LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11489", "l": "40S RIBOSOMAL PROTEIN SA", "d": [], "t": []}], "preferred_name": "40S RIBOSOMAL PROTEIN SA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11736:SF157", "l": "MELANOMA-ASSOCIATED ANTIGEN B10", "d": [], "t": []}], "preferred_name": "MELANOMA-ASSOCIATED ANTIGEN B10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12505", "l": "PHD FINGER TRANSCRIPTION FACTOR", "d": [], "t": []}], "preferred_name": "PHD FINGER TRANSCRIPTION FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23167:SF52", "l": "SMOOTHELIN", "d": [], "t": []}], "preferred_name": "SMOOTHELIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19278", "l": "OROTATE PHOSPHORIBOSYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "OROTATE PHOSPHORIBOSYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10527:SF6", "l": "IMPORTIN-4", "d": [], "t": []}], "preferred_name": "IMPORTIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13527:SF0", "l": "SAYSVFN DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "SAYSVFN DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:239", "l": "Neuromedin U receptors", "d": ["The neuromedin U receptors are two G-protein coupled receptors which bind the neuropeptide hormones neuromedin U and neuromedin S. There are two subtypes of the neuromedin U receptor, each encoded by a separate gene ( NMUR1, NMUR2 )."], "t": []}], "preferred_name": "Neuromedin U receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18867", "l": "RAD50", "d": [], "t": []}], "preferred_name": "RAD50", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21646:SF40", "l": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22", "d": [], "t": []}], "preferred_name": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15617:SF1", "l": "TRANSCRIPTION FACTOR GIBBIN", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR GIBBIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46879:SF1", "l": "SUSHI DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "SUSHI DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14710", "l": "GEM-ASSOCIATED PROTEIN 6", "d": [], "t": []}], "preferred_name": "GEM-ASSOCIATED PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15681", "l": "MAD2L1-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "MAD2L1-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1588", "l": "PI4KA lipid kinase complex", "d": ["The first step in PM phosphoinositide synthesis is the conversion of phosphatidylinositol (PI) to PI4P, the precursor of PI(4,5)P2 and PI(3,4,5)P3 This conversion is catalyzed by the PI4KIIIα complex."], "t": []}], "preferred_name": "PI4KA lipid kinase complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43999", "l": "DNAJ HOMOLOG SUBFAMILY C MEMBER 2", "d": [], "t": []}], "preferred_name": "DNAJ HOMOLOG SUBFAMILY C MEMBER 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43671:SF92", "l": "SERINE_THREONINE-PROTEIN KINASE NEK10", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE NEK10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31617", "l": "TRANSMEMBRANE PROTEIN 171", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 171", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10342:SF274", "l": "ARYLSULFATASE B", "d": [], "t": []}], "preferred_name": "ARYLSULFATASE B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11683", "l": "MYELIN PROTEOLIPID", "d": [], "t": []}], "preferred_name": "MYELIN PROTEOLIPID", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10845:SF184", "l": "REGULATOR OF G-PROTEIN SIGNALING 4", "d": [], "t": []}], "preferred_name": "REGULATOR OF G-PROTEIN SIGNALING 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24369", "l": "ANTIGEN BSP, PUTATIVE-RELATED", "d": [], "t": []}], "preferred_name": "ANTIGEN BSP, PUTATIVE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15597:SF45", "l": "RNA BINDING PROTEIN FOX-1 HOMOLOG 1", "d": [], "t": []}], "preferred_name": "RNA BINDING PROTEIN FOX-1 HOMOLOG 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14889:SF3", "l": "TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME", "d": [], "t": []}], "preferred_name": "TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10438", "l": "THIOREDOXIN", "d": [], "t": []}], "preferred_name": "THIOREDOXIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12027:SF86", "l": "PROTEIN WNT-2", "d": [], "t": []}], "preferred_name": "PROTEIN WNT-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24067:SF148", "l": "UBIQUITIN-CONJUGATING ENZYME E2 R2", "d": [], "t": []}], "preferred_name": "UBIQUITIN-CONJUGATING ENZYME E2 R2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12790:SF0", "l": "RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED", "d": [], "t": []}], "preferred_name": "RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46750:SF1", "l": "KUNITZ-TYPE PROTEASE INHIBITOR 1", "d": [], "t": []}], "preferred_name": "KUNITZ-TYPE PROTEASE INHIBITOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46224", "l": "ANKYRIN REPEAT FAMILY PROTEIN", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT FAMILY PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23266:SF367", "l": "IMMUNOGLOBULIN KAPPA CONSTANT", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN KAPPA CONSTANT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11850:SF205", "l": "HOMEOBOX PROTEIN TGIF2LX-RELATED", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN TGIF2LX-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11595", "l": "EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13556", "l": "TRANSCRIPTIONAL ADAPTER 3-RELATED", "d": [], "t": []}], "preferred_name": "TRANSCRIPTIONAL ADAPTER 3-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1539", "l": "p120 catenin family", "d": [], "t": []}], "preferred_name": "p120 catenin family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11662", "l": "SOLUTE CARRIER FAMILY 17", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10476:SF17", "l": "CHARGED MULTIVESICULAR BODY PROTEIN 1A", "d": [], "t": []}], "preferred_name": "CHARGED MULTIVESICULAR BODY PROTEIN 1A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3719", "l": "DOP1 leucine zipper like protein family", "d": ["The DOP1 family encode large proteins with leucine zipper like domains that are conserved from yeast to human. DOP1 proteins act in multiple cellular processes that involve membrane trafficking. Dysregulation of DOP1 family proteins is linked to developmental defects during gastrulation, as well as to neurological conditions and diseases like Down syndrome and Peters anomaly."], "t": []}], "preferred_name": "DOP1 leucine zipper like protein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23200:SF48", "l": "METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22739:SF20", "l": "ACTIN-BINDING RHO-ACTIVATING PROTEIN", "d": [], "t": []}], "preferred_name": "ACTIN-BINDING RHO-ACTIVATING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24006:SF711", "l": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 29", "d": [], "t": []}], "preferred_name": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 29", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23317:SF71", "l": "DEDICATOR OF CYTOKINESIS PROTEIN 10", "d": [], "t": []}], "preferred_name": "DEDICATOR OF CYTOKINESIS PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15468:SF7", "l": "SCIELLIN", "d": [], "t": []}], "preferred_name": "SCIELLIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24235:SF10", "l": "NEUROPEPTIDE Y RECEPTOR TYPE 5", "d": [], "t": []}], "preferred_name": "NEUROPEPTIDE Y RECEPTOR TYPE 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14555", "l": "MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN  MOBP -RELATED", "d": [], "t": []}], "preferred_name": "MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN  MOBP -RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43355:SF2", "l": "FLAVIN REDUCTASE (NADPH)", "d": [], "t": []}], "preferred_name": "FLAVIN REDUCTASE (NADPH)", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11552", "l": "GLUCOSE-METHANOL-CHOLINE  GMC  OXIDOREDUCTASE", "d": [], "t": []}], "preferred_name": "GLUCOSE-METHANOL-CHOLINE  GMC  OXIDOREDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21646:SF29", "l": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 11", "d": [], "t": []}], "preferred_name": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19282:SF25", "l": "UROPLAKIN-1A", "d": [], "t": []}], "preferred_name": "UROPLAKIN-1A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12138:SF149", "l": "SUBFAMILY NOT NAMED", "d": [], "t": []}], "preferred_name": "SUBFAMILY NOT NAMED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24399:SF8", "l": "ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17", "d": [], "t": []}], "preferred_name": "ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 17", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46877:SF11", "l": "EPHRIN TYPE-B RECEPTOR 2", "d": [], "t": []}], "preferred_name": "EPHRIN TYPE-B RECEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1331", "l": "WASH complex", "d": ["This is an actin-regulating complex that is recruited to endosomes by interactions with the retromer complex and plays a role in endosomal sorting."], "t": []}], "preferred_name": "WASH complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10794:SF39", "l": "PROTEIN ABHD15", "d": [], "t": []}], "preferred_name": "PROTEIN ABHD15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10602", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21444:SF16", "l": "RECEPTOR FOR RETINOL UPTAKE STRA6", "d": [], "t": []}], "preferred_name": "RECEPTOR FOR RETINOL UPTAKE STRA6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46939:SF1", "l": "ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14165:SF3", "l": "MAJOR VAULT PROTEIN", "d": [], "t": []}], "preferred_name": "MAJOR VAULT PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19862:SF14", "l": "WD REPEAT-CONTAINING PROTEIN 48", "d": [], "t": []}], "preferred_name": "WD REPEAT-CONTAINING PROTEIN 48", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24243:SF45", "l": "GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR", "d": [], "t": []}], "preferred_name": "GASTRIN_CHOLECYSTOKININ TYPE B RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13170:SF16", "l": "PROTEIN O-GLCNACASE", "d": [], "t": []}], "preferred_name": "PROTEIN O-GLCNACASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23088", "l": "NITRILASE-RELATED", "d": [], "t": []}], "preferred_name": "NITRILASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10199:SF92", "l": "THROMBOSPONDIN-4", "d": [], "t": []}], "preferred_name": "THROMBOSPONDIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15963", "l": "GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10909:SF352", "l": "ACYL-COENZYME A OXIDASE-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "ACYL-COENZYME A OXIDASE-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3522", "l": "Pre-mRNA processing factor kinase PRP4K family", "d": ["PRP4K is the sole member of a CMGC kinase subfamily."], "t": []}], "preferred_name": "Pre-mRNA processing factor kinase PRP4K family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35256:SF1", "l": "EXPRESSED SEQUENCE AI429214", "d": [], "t": []}], "preferred_name": "EXPRESSED SEQUENCE AI429214", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11799:SF16", "l": "SERUM PARAOXONASE_ARYLESTERASE 1", "d": [], "t": []}], "preferred_name": "SERUM PARAOXONASE_ARYLESTERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:617", "l": "Kelch like", "d": ["Kelch proteins (and Kelch-like proteins) are a widespread group of proteins that contain multiple Kelch motifs. The kelch domain generally occurs as a set of five to seven kelch repeats that form a beta-propeller tertiary structure. Kelch-repeat beta-propellers are generally involved in protein-protein interactions, though the large diversity of domain architectures and limited sequence identity between kelch motifs make characterisation of the kelch superfamily difficult."], "t": []}], "preferred_name": "Kelch like", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10978", "l": "SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT", "d": [], "t": []}], "preferred_name": "SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:10", "l": "Vanin family", "d": [], "t": []}], "preferred_name": "Vanin family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21373", "l": "GLUCOSE REPRESSIBLE PROTEIN MAK10", "d": [], "t": []}], "preferred_name": "GLUCOSE REPRESSIBLE PROTEIN MAK10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13120:SF0", "l": "PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A", "d": [], "t": []}], "preferred_name": "PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13976:SF33", "l": "HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H2", "d": [], "t": []}], "preferred_name": "HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24115:SF744", "l": "KINESIN-LIKE PROTEIN KIF3B", "d": [], "t": []}], "preferred_name": "KINESIN-LIKE PROTEIN KIF3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3420", "l": "NIMA related kinase family", "d": ["The NIMA family of serine/threonine kinases is a diverse group of protein kinases implicated in a wide variety of cellular processes, including cilia regulation, microtubule dynamics, mitotic processes, cell growth, and DNA damage response."], "t": []}], "preferred_name": "NIMA related kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10322", "l": "DNA POLYMERASE CATALYTIC SUBUNIT", "d": [], "t": []}], "preferred_name": "DNA POLYMERASE CATALYTIC SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10797:SF79", "l": "CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7", "d": [], "t": []}], "preferred_name": "CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10621", "l": "UV EXCISION REPAIR PROTEIN RAD23", "d": [], "t": []}], "preferred_name": "UV EXCISION REPAIR PROTEIN RAD23", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11915", "l": "SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN", "d": [], "t": []}], "preferred_name": "SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23339:SF77", "l": "DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14A", "d": [], "t": []}], "preferred_name": "DUAL SPECIFICITY PROTEIN PHOSPHATASE CDC14A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37882:SF1", "l": "CHROMOSOME 2 OPEN READING FRAME 74", "d": [], "t": []}], "preferred_name": "CHROMOSOME 2 OPEN READING FRAME 74", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15740:SF2", "l": "ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN 2", "d": [], "t": []}], "preferred_name": "ACTIVITY-DEPENDENT NEUROPROTECTOR HOMEOBOX PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10824:SF16", "l": "ACYL-COENZYME A THIOESTERASE 1-RELATED", "d": [], "t": []}], "preferred_name": "ACYL-COENZYME A THIOESTERASE 1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46384:SF1", "l": "MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19944:SF43", "l": "HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN", "d": [], "t": []}], "preferred_name": "HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11437:SF20", "l": "INACTIVE RIBONUCLEASE-LIKE PROTEIN 12-RELATED", "d": [], "t": []}], "preferred_name": "INACTIVE RIBONUCLEASE-LIKE PROTEIN 12-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12874:SF29", "l": "F-BOX ONLY PROTEIN 9", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22607:SF4", "l": "CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "CYCLIN-DEPENDENT KINASE 2-ASSOCIATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3427", "l": "Cupredoxin superfamily", "d": [], "t": []}], "preferred_name": "Cupredoxin superfamily", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46269:SF3", "l": "EPIPHYCAN", "d": [], "t": []}], "preferred_name": "EPIPHYCAN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10288:SF158", "l": "INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3", "d": [], "t": []}], "preferred_name": "INSULIN-LIKE GROWTH FACTOR 2 MRNA-BINDING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16277:SF6", "l": "CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4", "d": [], "t": []}], "preferred_name": "CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45627:SF1", "l": "ADENYLATE CYCLASE TYPE 8", "d": [], "t": []}], "preferred_name": "ADENYLATE CYCLASE TYPE 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2293", "l": "Proteins encoded by multiple genes", "d": ["This group lists protein coding genes that encode a protein that is identical to that encoded by another gene or genes. The list was constructed from a set of UniProt accessions that are associated with multiple genes. The list is limited to genes on the current reference assembly and excludes proteins encoded by read-through transcripts. Genes that encode the same protein share root symbols. Note the H3C root is associated with two different proteins - one encoded by a cluster of genes on 6p22.1 and the other by a cluster of three genes on 1q21.2 (H3C13-15)."], "t": []}], "preferred_name": "Proteins encoded by multiple genes", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36132:SF1", "l": "TRANSMEMBRANE PROTEIN 221", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 221", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21502", "l": "ZINC FINGER PROTEIN DZIP1", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN DZIP1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF11", "l": "PROTOCADHERIN-15", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN-15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13869:SF7", "l": "MYELIN PROTEIN P0", "d": [], "t": []}], "preferred_name": "MYELIN PROTEIN P0", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14021:SF15", "l": "IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB", "d": [], "t": []}], "preferred_name": "IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24103:SF46", "l": "E3 UBIQUITIN-PROTEIN LIGASE TRIM21", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE TRIM21", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23050:SF417", "l": "CALMODULIN-LIKE PROTEIN 6", "d": [], "t": []}], "preferred_name": "CALMODULIN-LIKE PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11349:SF54", "l": "NUCLEOSIDE DIPHOSPHATE KINASE 3", "d": [], "t": []}], "preferred_name": "NUCLEOSIDE DIPHOSPHATE KINASE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46759:SF1", "l": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 72", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13340", "l": "GATA ZINC FINGER DOMAIN-CONTAINING", "d": [], "t": []}], "preferred_name": "GATA ZINC FINGER DOMAIN-CONTAINING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45842:SF5", "l": "LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:84", "l": "Zinc fingers matrin-type", "d": ["Genes encoding proteins that contain U1-type zinc finger domains, a family of C2H2-type zinc fingers present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins."], "t": []}], "preferred_name": "Zinc fingers matrin-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23108", "l": "METHYLTRANSFERASE-RELATED", "d": [], "t": []}], "preferred_name": "METHYLTRANSFERASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22948:SF75", "l": "A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13964:SF25", "l": "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A", "d": [], "t": []}], "preferred_name": "AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 5A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22968:SF26", "l": "SERINE_THREONINE-PROTEIN KINASE D3", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE D3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18884:SF67", "l": "SEPTIN-2", "d": [], "t": []}], "preferred_name": "SEPTIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11528:SF78", "l": "HEAT SHOCK PROTEIN HSP 90-BETA 2-RELATED", "d": [], "t": []}], "preferred_name": "HEAT SHOCK PROTEIN HSP 90-BETA 2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10605:SF45", "l": "BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 4", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23262:SF227", "l": "KERATIN-ASSOCIATED PROTEIN 10-7", "d": [], "t": []}], "preferred_name": "KERATIN-ASSOCIATED PROTEIN 10-7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15349:SF0", "l": "ENDOTHELIAL PROTEIN C RECEPTOR", "d": [], "t": []}], "preferred_name": "ENDOTHELIAL PROTEIN C RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34446:SF4", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 10", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17613:SF10", "l": "TESTIS-SPECIFIC PROTEIN TEX28", "d": [], "t": []}], "preferred_name": "TESTIS-SPECIFIC PROTEIN TEX28", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:943", "l": "Dynactin subunits", "d": ["Dynactin or Dynein activator complex is a multi-subunit protein found in eukaryotic cells that aids in bidirectional intracellular transport by binding to dynein and kinesin-2 and linking them to the organelle or vesicle to be transported."], "t": []}], "preferred_name": "Dynactin subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12702:SF3", "l": "EXOCYST COMPLEX COMPONENT 6B", "d": [], "t": []}], "preferred_name": "EXOCYST COMPLEX COMPONENT 6B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12668:SF11", "l": "TRANSMEMBRANE PROTEIN 14A", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 14A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11736", "l": "MELANOMA-ASSOCIATED ANTIGEN  MAGE ANTIGEN", "d": [], "t": []}], "preferred_name": "MELANOMA-ASSOCIATED ANTIGEN  MAGE ANTIGEN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21563:SF3", "l": "ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12107", "l": "VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT", "d": [], "t": []}], "preferred_name": "VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44974:SF1", "l": "V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:530", "l": "CERS class homeoboxes", "d": [], "t": []}], "preferred_name": "CERS class homeoboxes", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31981:SF1", "l": "GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN", "d": [], "t": []}], "preferred_name": "GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1226", "l": "LY6/PLAUR domain containing", "d": [], "t": []}], "preferred_name": "LY6/PLAUR domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43599", "l": "MULTIFUNCTIONAL PROTEIN ADE2", "d": [], "t": []}], "preferred_name": "MULTIFUNCTIONAL PROTEIN ADE2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10353:SF10", "l": "KLOTHO", "d": [], "t": []}], "preferred_name": "KLOTHO", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1950", "l": "Heterogeneous nuclear ribonucleoproteins", "d": ["Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein present in the cell nucleus during gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA). The presence of the proteins bound to a pre-mRNA molecule serves as a signal that the pre-mRNA is not yet fully processed and therefore not ready for export to the cytoplasm. Since most mature RNA is exported from the nucleus relatively quickly, most RNA-binding protein in the nucleus exist as heterogeneous ribonucleoprotein particles. After splicing has occurred, the proteins remain bound to spliced introns and target them for degradation.  hnRNPs are also integral to the 40s subunit of the ribosome and therefore important for the translation of mRNA in the cytoplasm. However, hnRNPs also have their own nuclear localization sequences (NLS) and are therefore found mainly in the nucleus. Though it is known that a few hnRNPs shuttle between the cytoplasm and nucleus, immunofluorescence microscopy with hnRNP-specific antibodies shows nucleoplasmic localization of these proteins with little staining in the nucleolus or cytoplasm. This is likely because of its major role in binding to newly transcribed RNAs. High-resolution immunoelectron microscopy has shown that hnRNPs localize predominantly to the border regions of chromatin, where it has access to these nascent RNAs.The proteins involved in the hnRNP complexes are collectively known as heterogeneous ribonucleoproteins. They include protein K and polypyrimidine tract-binding protein (PTB), which is regulated by phosphorylation catalyzed by protein kinase A and is responsible for suppressing RNA splicing at a particular exon by blocking access of the spliceosome to the polypyrimidine tract. hnRNPs are also responsible for strengthening and inhibiting splice sites by making such sites more or less accessible to the spliceosome. Cooperative interactions between attached hnRNPs may encourage certain splicing combinations while inhibiting others."], "t": []}], "preferred_name": "Heterogeneous nuclear ribonucleoproteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13936:SF2", "l": "PROFILIN-3", "d": [], "t": []}], "preferred_name": "PROFILIN-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28641", "l": "FAMILY NOT NAMED", "d": [], "t": []}], "preferred_name": "FAMILY NOT NAMED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37153:SF1", "l": "HYPOTHETICAL LOC292874", "d": [], "t": []}], "preferred_name": "HYPOTHETICAL LOC292874", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1412", "l": "Envelope ERV derived genes", "d": ["Intact envelope genes have been shown to be transcribed in several healthy tissues, and the conservation in an otherwise degenerated ERV locus has led to speculations about a likely beneficial role for the host. These include (i) protecting the fetus due to immunomodulatory properties via an immunosuppressive domain located in the TM subunit of the envelope, (ii) preventing present-day retroviral infections by inhibiting cell entry of related exogenous retroviruses that use a common surface receptor, a process called receptor interference in which the receptor-binding-domain of SU blocks the receptor, or (iii) being used as triggers to provide cell-cell fusion in which the fusion machinery of TM is activated by binding of SU to a cellular receptor."], "t": []}], "preferred_name": "Envelope ERV derived genes", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19367:SF21", "l": "T CELL RECEPTOR ALPHA VARIABLE 8-2", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR ALPHA VARIABLE 8-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF407", "l": "ZINC FINGER PROTEIN 93", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 93", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3533", "l": "Choline kinase family", "d": ["Choline kinases catalyse the conversion of choline to phosphocholine, which is further converted to cytidine diphosphate-coline (CDP-choline) in the biosynthesis of phosphatidylcholine (PC). PC is a major constituent of the phospholipid bilayer which constitutes the eukaryotic cell membrane, and regulates cell signal transduction. Functional choline kinase exists as a dimer, and can form homodimers or heterodimers with differential dynamics dependent on the tissue type. CHKA homodimers display higher enzymatic activity than CHKB homodimers and CHKA/B heterodimers with tissues differing in their relative expression of the varying isoforms."], "t": []}], "preferred_name": "Choline kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24226", "l": "G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1", "d": [], "t": []}], "preferred_name": "G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21569:SF1", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN US9M", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN US9M", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10352", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11477:SF1", "l": "TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION ELONGATION FACTOR A PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22939:SF127", "l": "SERINE PROTEASE HTRA2, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "SERINE PROTEASE HTRA2, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1443", "l": "M20 metallopeptidases", "d": ["These genes encode zinc dependent metallopeptidases that require cocatalytic metal ions."], "t": []}], "preferred_name": "M20 metallopeptidases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10800", "l": "PULMONARY SURFACTANT-ASSOCIATED PROTEIN C", "d": [], "t": []}], "preferred_name": "PULMONARY SURFACTANT-ASSOCIATED PROTEIN C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11453:SF20", "l": "ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 4", "d": [], "t": []}], "preferred_name": "ELECTROGENIC SODIUM BICARBONATE COTRANSPORTER 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11636:SF81", "l": "POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3", "d": [], "t": []}], "preferred_name": "POU DOMAIN, CLASS 2, TRANSCRIPTION FACTOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15138", "l": "TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23430:SF56", "l": "HISTONE H2A TYPE 1-D", "d": [], "t": []}], "preferred_name": "HISTONE H2A TYPE 1-D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45659:SF11", "l": "HOMEOBOX PROTEIN HOX-B7", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN HOX-B7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19441:SF97", "l": "WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 3", "d": [], "t": []}], "preferred_name": "WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15821:SF0", "l": "TRANSCRIPTIONAL ACTIVATOR MN1", "d": [], "t": []}], "preferred_name": "TRANSCRIPTIONAL ACTIVATOR MN1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:489", "l": "Coiled-coil-helix-coiled-coil-helix domain containing proteins", "d": [], "t": []}], "preferred_name": "Coiled-coil-helix-coiled-coil-helix domain containing proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10218:SF359", "l": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1", "d": [], "t": []}], "preferred_name": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22980", "l": "CORTISTATIN", "d": [], "t": []}], "preferred_name": "CORTISTATIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12609", "l": "MICROTUBULE ASSOCIATED PROTEIN XMAP215", "d": [], "t": []}], "preferred_name": "MICROTUBULE ASSOCIATED PROTEIN XMAP215", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22957:SF27", "l": "TBC1 DOMAIN FAMILY MEMBER 13", "d": [], "t": []}], "preferred_name": "TBC1 DOMAIN FAMILY MEMBER 13", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46792:SF2", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 80", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 80", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12474:SF2", "l": "SESTRIN-2", "d": [], "t": []}], "preferred_name": "SESTRIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10746", "l": "50S RIBOSOMAL PROTEIN L4", "d": [], "t": []}], "preferred_name": "50S RIBOSOMAL PROTEIN L4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23288:SF8", "l": "RNA POLYMERASE II ELONGATION FACTOR ELL2", "d": [], "t": []}], "preferred_name": "RNA POLYMERASE II ELONGATION FACTOR ELL2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13110", "l": "U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3", "d": [], "t": []}], "preferred_name": "U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15574:SF42", "l": "DDB1- AND CUL4-ASSOCIATED FACTOR 8-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "DDB1- AND CUL4-ASSOCIATED FACTOR 8-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19143:SF31", "l": "ANGIOPOIETIN-4", "d": [], "t": []}], "preferred_name": "ANGIOPOIETIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12939:SF5", "l": "ZETA-SARCOGLYCAN", "d": [], "t": []}], "preferred_name": "ZETA-SARCOGLYCAN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22461:SF1", "l": "SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31690", "l": "FUCOSE MUTAROTASE", "d": [], "t": []}], "preferred_name": "FUCOSE MUTAROTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15044", "l": "NEUROPEPTIDE FF", "d": [], "t": []}], "preferred_name": "NEUROPEPTIDE FF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13104:SF0", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13809", "l": "GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT", "d": [], "t": []}], "preferred_name": "GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21041:SF6", "l": "DC-STAMP DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "DC-STAMP DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13723:SF144", "l": "ADAMTS-LIKE PROTEIN 4", "d": [], "t": []}], "preferred_name": "ADAMTS-LIKE PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45619:SF8", "l": "SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1864", "l": "MicroRNA MIR1289 family", "d": [], "t": []}], "preferred_name": "MicroRNA MIR1289 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39223:SF1", "l": "RIKEN CDNA 1700029H14 GENE", "d": [], "t": []}], "preferred_name": "RIKEN CDNA 1700029H14 GENE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3771", "l": "STE11 kinase family", "d": [], "t": []}], "preferred_name": "STE11 kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12184:SF1", "l": "UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1", "d": [], "t": []}], "preferred_name": "UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19443:SF10", "l": "HEXOKINASE-1", "d": [], "t": []}], "preferred_name": "HEXOKINASE-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23035", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46079:SF3", "l": "FERM DOMAIN-CONTAINING PROTEIN 4A", "d": [], "t": []}], "preferred_name": "FERM DOMAIN-CONTAINING PROTEIN 4A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46568:SF1", "l": "ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL", "d": [], "t": []}], "preferred_name": "ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12764", "l": "WD REPEAT DOMAIN-RELATED", "d": [], "t": []}], "preferred_name": "WD REPEAT DOMAIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14187:SF46", "l": "HEAT SHOCK 70 KDA PROTEIN 12A", "d": [], "t": []}], "preferred_name": "HEAT SHOCK 70 KDA PROTEIN 12A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24062:SF174", "l": "VOMERONASAL TYPE-1 RECEPTOR 5", "d": [], "t": []}], "preferred_name": "VOMERONASAL TYPE-1 RECEPTOR 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:158", "l": "WWC family", "d": [], "t": []}], "preferred_name": "WWC family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46685:SF1", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN US15M", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN US15M", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10336:SF33", "l": "1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-3", "d": [], "t": []}], "preferred_name": "1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23268:SF115", "l": "T CELL RECEPTOR BETA VARIABLE 10-3", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA VARIABLE 10-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13421", "l": "SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3", "d": [], "t": []}], "preferred_name": "SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12478", "l": "DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4", "d": [], "t": []}], "preferred_name": "DNA-DAMAGE-INDUCIBLE TRANSCRIPT 4 PROTEIN DDIT4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1641", "l": "C1q domain containing", "d": [], "t": []}], "preferred_name": "C1q domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:580", "l": "GTPases, IMAP", "d": [], "t": []}], "preferred_name": "GTPases, IMAP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14167:SF68", "l": "DREBRIN-LIKE PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "DREBRIN-LIKE PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21254", "l": "C2 DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "C2 DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10110:SF87", "l": "SODIUM_HYDROGEN EXCHANGER 10", "d": [], "t": []}], "preferred_name": "SODIUM_HYDROGEN EXCHANGER 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44899:SF4", "l": "SERINE_THREONINE-PROTEIN KINASE NEK1", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE NEK1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21207:SF2", "l": "PARKIN COREGULATED GENE PROTEIN", "d": [], "t": []}], "preferred_name": "PARKIN COREGULATED GENE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24404:SF28", "l": "ZINC FINGER PROTEIN EOS", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN EOS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21325:SF52", "l": "PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED", "d": [], "t": []}], "preferred_name": "PHOSPHOLIPASE B1, MEMBRANE-ASSOCIATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46109", "l": "PROTEIN LIN-28", "d": [], "t": []}], "preferred_name": "PROTEIN LIN-28", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10937:SF10", "l": "GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2", "d": [], "t": []}], "preferred_name": "GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19331:SF441", "l": "SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130", "d": [], "t": []}], "preferred_name": "SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24070:SF245", "l": "RAS-RELATED PROTEIN R-RAS", "d": [], "t": []}], "preferred_name": "RAS-RELATED PROTEIN R-RAS", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15075:SF6", "l": "ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B", "d": [], "t": []}], "preferred_name": "ALPHA-1,6-MANNOSYLGLYCOPROTEIN 6-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11640", "l": "NEPHRIN", "d": [], "t": []}], "preferred_name": "NEPHRIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11274", "l": "RAD25/XP-B DNA REPAIR HELICASE", "d": [], "t": []}], "preferred_name": "RAD25/XP-B DNA REPAIR HELICASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF518", "l": "IMMUNOGLOBULIN KAPPA VARIABLE 2-29", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN KAPPA VARIABLE 2-29", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46007", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48039:SF5", "l": "RNA-BINDING PROTEIN 28", "d": [], "t": []}], "preferred_name": "RNA-BINDING PROTEIN 28", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11243:SF25", "l": "GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7", "d": [], "t": []}], "preferred_name": "GROWTH FACTOR RECEPTOR-BOUND PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24229:SF4", "l": "CHEMERIN-LIKE RECEPTOR 2", "d": [], "t": []}], "preferred_name": "CHEMERIN-LIKE RECEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33663:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 177", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 177", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23285", "l": "RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24214:SF6", "l": "PDZ AND LIM DOMAIN PROTEIN 4", "d": [], "t": []}], "preferred_name": "PDZ AND LIM DOMAIN PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14234:SF20", "l": "PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR-ASSOCIATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12864:SF3", "l": "GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG", "d": [], "t": []}], "preferred_name": "GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46841:SF3", "l": "OX-2 MEMBRANE GLYCOPROTEIN", "d": [], "t": []}], "preferred_name": "OX-2 MEMBRANE GLYCOPROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12867", "l": "GLYCOSYL TRANSFERASE-RELATED", "d": [], "t": []}], "preferred_name": "GLYCOSYL TRANSFERASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31844:SF1", "l": "PROTEIN FAM168A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM168A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20648:SF13", "l": "ELONGIN-C", "d": [], "t": []}], "preferred_name": "ELONGIN-C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10934", "l": "60S RIBOSOMAL PROTEIN L18", "d": [], "t": []}], "preferred_name": "60S RIBOSOMAL PROTEIN L18", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1938", "l": "H3 histones", "d": ["Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. The term 'Histone H3' alone is purposely ambiguous in that it does not distinguish between sequence variants or modification state. Histone H3 is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes."], "t": []}], "preferred_name": "H3 histones", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF483", "l": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-25", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11245:SF2", "l": "STANNIOCALCIN-2", "d": [], "t": []}], "preferred_name": "STANNIOCALCIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15454:SF47", "l": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 23", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11081", "l": "FLAP ENDONUCLEASE FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "FLAP ENDONUCLEASE FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11814:SF17", "l": "SOLUTE CARRIER FAMILY 26 MEMBER 9", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 26 MEMBER 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46957:SF7", "l": "USHERIN", "d": [], "t": []}], "preferred_name": "USHERIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16932:SF36", "l": "INTERFERON ALPHA-INDUCIBLE PROTEIN 27-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "INTERFERON ALPHA-INDUCIBLE PROTEIN 27-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1503", "l": "U5 small nuclear ribonucleoprotein", "d": ["The U5 snRNP complex is involved in pre-mRNA splicing events. Of the six U5 snRNP-specific proteins, three are NTPases. DDX23 and SNRNP200 are members of the DEXD/H box family and EFTUD2 is the sole GTPase identified in the spliceosome to date. The NTPases of the U5 snRNP are involved in the critical switch in which U1 is replaced by U6 at the 5 prime splice site."], "t": []}], "preferred_name": "U5 small nuclear ribonucleoprotein", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24391:SF26", "l": "HISTONE H4 TRANSCRIPTION FACTOR", "d": [], "t": []}], "preferred_name": "HISTONE H4 TRANSCRIPTION FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16223", "l": "TRANSCRIPTION FACTOR BHLH83-RELATED", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR BHLH83-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22950:SF188", "l": "PROTON-COUPLED AMINO ACID TRANSPORTER 1", "d": [], "t": []}], "preferred_name": "PROTON-COUPLED AMINO ACID TRANSPORTER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21258:SF44", "l": "DOCKING PROTEIN 4", "d": [], "t": []}], "preferred_name": "DOCKING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10157:SF31", "l": "DBH-LIKE MONOOXYGENASE PROTEIN 2-RELATED", "d": [], "t": []}], "preferred_name": "DBH-LIKE MONOOXYGENASE PROTEIN 2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24034:SF49", "l": "LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 2", "d": [], "t": []}], "preferred_name": "LATENT-TRANSFORMING GROWTH FACTOR BETA-BINDING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20886:SF8", "l": "VANG-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "VANG-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13375", "l": "FMS INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "FMS INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12840", "l": "NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16515", "l": "PR DOMAIN ZINC FINGER PROTEIN", "d": [], "t": []}], "preferred_name": "PR DOMAIN ZINC FINGER PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16070:SF2", "l": "PROTEIN FAM222A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM222A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11256:SF46", "l": "INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1", "d": [], "t": []}], "preferred_name": "INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19282:SF471", "l": "CD63 ANTIGEN", "d": [], "t": []}], "preferred_name": "CD63 ANTIGEN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11771", "l": "LIPOXYGENASE", "d": [], "t": []}], "preferred_name": "LIPOXYGENASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15453:SF8", "l": "TUMOR SUPPRESSOR CANDIDATE 2", "d": [], "t": []}], "preferred_name": "TUMOR SUPPRESSOR CANDIDATE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24383:SF10", "l": "ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44", "d": [], "t": []}], "preferred_name": "ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10257:SF80", "l": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT EPSILON ISOFORM", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23129:SF3", "l": "FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 1", "d": [], "t": []}], "preferred_name": "FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11346:SF26", "l": "GALECTIN-3", "d": [], "t": []}], "preferred_name": "GALECTIN-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13771", "l": "INTERCELLULAR ADHESION MOLECULE", "d": [], "t": []}], "preferred_name": "INTERCELLULAR ADHESION MOLECULE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12170", "l": "MACROPHAGE ERYTHROBLAST ATTACHER-RELATED", "d": [], "t": []}], "preferred_name": "MACROPHAGE ERYTHROBLAST ATTACHER-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11533:SF294", "l": "THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME", "d": [], "t": []}], "preferred_name": "THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32289", "l": "PROTEIN FAM167A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM167A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31437:SF1", "l": "PROTEIN SREK1IP1", "d": [], "t": []}], "preferred_name": "PROTEIN SREK1IP1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26450:SF168", "l": "OLFACTORY RECEPTOR 51A2-RELATED", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 51A2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1090", "l": "Atypical chemokine receptors", "d": [], "t": []}], "preferred_name": "Atypical chemokine receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23382:SF3", "l": "MALATE DEHYDROGENASE, CYTOPLASMIC", "d": [], "t": []}], "preferred_name": "MALATE DEHYDROGENASE, CYTOPLASMIC", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3346", "l": "Zinc fingers ZNF750 C2HC-type", "d": ["ZNF750 is a transcription factor that controls epithelial homeostasis by inhibiting progenitor genes while inducing differentiation genes (<a href='https://pubmed.ncbi.nlm.nih.gov/25228645/'>PMID: 25228645</a>). Proteins containing this domain also include proline-rich protein 35. Its function is not clear."], "t": []}], "preferred_name": "Zinc fingers ZNF750 C2HC-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43880:SF2", "l": "ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH7", "d": [], "t": []}], "preferred_name": "ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22770:SF47", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF216", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF216", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31943", "l": "INTERLEUKIN-28 AND 29", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-28 AND 29", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23095:SF49", "l": "PARANEOPLASTIC ANTIGEN MA6F", "d": [], "t": []}], "preferred_name": "PARANEOPLASTIC ANTIGEN MA6F", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31107", "l": "APOPTOGENIC PROTEIN 1, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "APOPTOGENIC PROTEIN 1, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42921", "l": "ACETOACETYL-COA SYNTHETASE", "d": [], "t": []}], "preferred_name": "ACETOACETYL-COA SYNTHETASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16458", "l": "GLYCINE N-METHYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "GLYCINE N-METHYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48002:SF146", "l": "OLFACTORY RECEPTOR 4X2", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 4X2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22529", "l": "EPITHELIAL-STROMAL INTERACTION PROTEIN 1", "d": [], "t": []}], "preferred_name": "EPITHELIAL-STROMAL INTERACTION PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12064:SF26", "l": "METAL TRANSPORTER CNNM4", "d": [], "t": []}], "preferred_name": "METAL TRANSPORTER CNNM4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12940:SF0", "l": "SPLICING FACTOR ESS-2 HOMOLOG", "d": [], "t": []}], "preferred_name": "SPLICING FACTOR ESS-2 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24068:SF135", "l": "UBIQUITIN-CONJUGATING ENZYME E2 J2", "d": [], "t": []}], "preferred_name": "UBIQUITIN-CONJUGATING ENZYME E2 J2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14069:SF0", "l": "FILENSIN", "d": [], "t": []}], "preferred_name": "FILENSIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28652", "l": "TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26452:SF180", "l": "OLFACTORY RECEPTOR 14C36", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 14C36", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1540", "l": "Catenins", "d": [], "t": []}], "preferred_name": "Catenins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23093:SF17", "l": "GLUTAMATE-RICH PROTEIN 6B", "d": [], "t": []}], "preferred_name": "GLUTAMATE-RICH PROTEIN 6B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22574:SF12", "l": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5B", "d": [], "t": []}], "preferred_name": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19957:SF29", "l": "SYNTAXIN-19", "d": [], "t": []}], "preferred_name": "SYNTAXIN-19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44414:SF1", "l": "PROTEIN NEDD1", "d": [], "t": []}], "preferred_name": "PROTEIN NEDD1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13336:SF2", "l": "OCIA DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "OCIA DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15126", "l": "SH3-BINDING", "d": [], "t": []}], "preferred_name": "SH3-BINDING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45736", "l": "ZINC FINGER MYM-TYPE PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER MYM-TYPE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45850:SF4", "l": "SORTING NEXIN-6", "d": [], "t": []}], "preferred_name": "SORTING NEXIN-6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16675:SF155", "l": "T-CELL SURFACE GLYCOPROTEIN CD1C", "d": [], "t": []}], "preferred_name": "T-CELL SURFACE GLYCOPROTEIN CD1C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15157", "l": "UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN", "d": [], "t": []}], "preferred_name": "UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11267:SF104", "l": "T-BOX TRANSCRIPTION FACTOR TBX1", "d": [], "t": []}], "preferred_name": "T-BOX TRANSCRIPTION FACTOR TBX1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16840:SF3", "l": "GROWTH ARREST-SPECIFIC PROTEIN 1", "d": [], "t": []}], "preferred_name": "GROWTH ARREST-SPECIFIC PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48023", "l": "D-XYLOSE-PROTON SYMPORTER-LIKE 2", "d": [], "t": []}], "preferred_name": "D-XYLOSE-PROTON SYMPORTER-LIKE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21422:SF9", "l": "RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT", "d": [], "t": []}], "preferred_name": "RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15317:SF1", "l": "T-CELL SURFACE PROTEIN TACTILE", "d": [], "t": []}], "preferred_name": "T-CELL SURFACE PROTEIN TACTILE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48106:SF18", "l": "QUINONE OXIDOREDUCTASE PIG3", "d": [], "t": []}], "preferred_name": "QUINONE OXIDOREDUCTASE PIG3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28436", "l": "MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM5 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23266:SF377", "l": "NON-FUNCTIONAL IMMUNOGLOBULIN HEAVY VARIABLE 7-81-RELATED", "d": [], "t": []}], "preferred_name": "NON-FUNCTIONAL IMMUNOGLOBULIN HEAVY VARIABLE 7-81-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12391", "l": "ARP2/3 COMPLEX 21 KD SUBUNIT", "d": [], "t": []}], "preferred_name": "ARP2/3 COMPLEX 21 KD SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44215:SF1", "l": "WD REPEAT-CONTAINING PROTEIN 75", "d": [], "t": []}], "preferred_name": "WD REPEAT-CONTAINING PROTEIN 75", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13026:SF1", "l": "RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG A", "d": [], "t": []}], "preferred_name": "RIBOSOMAL RNA PROCESSING PROTEIN 1 HOMOLOG A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24082:SF231", "l": "NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3", "d": [], "t": []}], "preferred_name": "NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3794", "l": "Ataxin 3 family", "d": ["ATXN3 AND ATXN3L contain an N-terminal catalytic Josephin domain and two or three UIM motifs. Expansions of a polyglutamine tract in ATXN3 are associated with Spinocerebellar ataxia 3; ATXN3L also has a polyglutamine tract but unlike ATXN3 it does not appear to expand."], "t": []}], "preferred_name": "Ataxin 3 family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13196:SF22", "l": "DENN DOMAIN-CONTAINING PROTEIN 1A", "d": [], "t": []}], "preferred_name": "DENN DOMAIN-CONTAINING PROTEIN 1A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12845:SF3", "l": "RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 16", "d": [], "t": []}], "preferred_name": "RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 16", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF271", "l": "OLFACTORY RECEPTOR 2V1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 2V1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23023:SF81", "l": "DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 6-RELATED", "d": [], "t": []}], "preferred_name": "DIMETHYLANILINE MONOOXYGENASE [N-OXIDE-FORMING] 6-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28598", "l": "STAGA COMPLEX 65 SUBUNIT GAMMA", "d": [], "t": []}], "preferred_name": "STAGA COMPLEX 65 SUBUNIT GAMMA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12027:SF101", "l": "PROTEIN WNT-4", "d": [], "t": []}], "preferred_name": "PROTEIN WNT-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15478:SF4", "l": "PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 1", "d": [], "t": []}], "preferred_name": "PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY A MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3558", "l": "D-lactate dehydrogenase family", "d": ["Lactate exists in the human body as two optical isomers: L-lactate and D-lactate. L-lactate is produced from pyruvate during anaerobic glycolysis and present in blood at concentrations 100 times greater than D-lactate. D-lactate is acquired exogenously by consumption of foods, by metabolism of chemicals such as propylene glycol, by intestinal bacteria production, or endogenously by methylglyoxal metabolism—a toxic product that is converted to D-lactate. Different classes of lactate dehydrogenase act on the different isomers. LDHD is specific for D-lactate metabolism."], "t": []}], "preferred_name": "D-lactate dehydrogenase family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14611:SF6", "l": "TECTONIC-2", "d": [], "t": []}], "preferred_name": "TECTONIC-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1971", "l": "Shroom family", "d": [], "t": []}], "preferred_name": "Shroom family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13568", "l": "FAM11A, B PROTEIN", "d": [], "t": []}], "preferred_name": "FAM11A, B PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10091", "l": "ALDOSE-1-EPIMERASE", "d": [], "t": []}], "preferred_name": "ALDOSE-1-EPIMERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11558", "l": "SPERMIDINE/SPERMINE SYNTHASE", "d": [], "t": []}], "preferred_name": "SPERMIDINE/SPERMINE SYNTHASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18966:SF364", "l": "GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B", "d": [], "t": []}], "preferred_name": "GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15011", "l": "APOLIPOPROTEIN F", "d": [], "t": []}], "preferred_name": "APOLIPOPROTEIN F", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24334:SF2", "l": "HOMEOBOX PROTEIN GBX-1", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN GBX-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24253:SF103", "l": "TRANSMEMBRANE PROTEASE SERINE 7", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEASE SERINE 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24037", "l": "HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1", "d": [], "t": []}], "preferred_name": "HEART DEVELOPMENT PROTEIN WITH EGF-LIKE DOMAINS 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11469", "l": "GLUCOSE-6-PHOSPHATE ISOMERASE", "d": [], "t": []}], "preferred_name": "GLUCOSE-6-PHOSPHATE ISOMERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11953", "l": "EXOSOME COMPLEX COMPONENT", "d": [], "t": []}], "preferred_name": "EXOSOME COMPLEX COMPONENT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15402", "l": "TRANSCRIPTION FACTOR-LIKE 5 PROTEIN", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR-LIKE 5 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11440", "l": "LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED", "d": [], "t": []}], "preferred_name": "LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23239", "l": "INTERMEDIATE FILAMENT", "d": [], "t": []}], "preferred_name": "INTERMEDIATE FILAMENT", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18945:SF401", "l": "NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4", "d": [], "t": []}], "preferred_name": "NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24347:SF197", "l": "CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1", "d": [], "t": []}], "preferred_name": "CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:354", "l": "Immunoglobulin lambda (IGL) orphons", "d": ["These are IGL genes that are found outside of the 22q11.2 IGL locus and therefore cannot form part of an immunoglobulin-encoding gene."], "t": []}], "preferred_name": "Immunoglobulin lambda (IGL) orphons", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23504:SF31", "l": "MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10", "d": [], "t": []}], "preferred_name": "MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12092", "l": "PLECKSTRIN", "d": [], "t": []}], "preferred_name": "PLECKSTRIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45616:SF3", "l": "KERATIN, TYPE II CYTOSKELETAL 4", "d": [], "t": []}], "preferred_name": "KERATIN, TYPE II CYTOSKELETAL 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45975", "l": "NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF", "d": [], "t": []}], "preferred_name": "NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45783:SF6", "l": "KINESIN LIGHT CHAIN 4", "d": [], "t": []}], "preferred_name": "KINESIN LIGHT CHAIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31539", "l": "CENTROSOMAL PROTEIN OF 19K CEP19", "d": [], "t": []}], "preferred_name": "CENTROSOMAL PROTEIN OF 19K CEP19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24006:SF687", "l": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10", "d": [], "t": []}], "preferred_name": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21642", "l": "CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG", "d": [], "t": []}], "preferred_name": "CEREBRAL CAVERNOUS MALFORMATIONS PROTEIN 2 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10806:SF36", "l": "SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11A", "d": [], "t": []}], "preferred_name": "SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21600:SF83", "l": "PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16915", "l": "IMMEDIATE EARLY RESPONSE 3", "d": [], "t": []}], "preferred_name": "IMMEDIATE EARLY RESPONSE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11515", "l": "GLYCOPROTEIN HORMONE BETA CHAIN", "d": [], "t": []}], "preferred_name": "GLYCOPROTEIN HORMONE BETA CHAIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:415", "l": "V-type ATPase subunits", "d": ["Vacuolar-type H +-ATPase ( V-ATPase ) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms. V-ATPases acidify a wide array of intracellular organelles and pump protons across the plasma membranes of numerous cell types. V-ATPases couple the energy of ATP hydrolysis to proton transport across intracellular and plasma membranes of eukaryotic cells."], "t": []}], "preferred_name": "V-type ATPase subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10041:SF5", "l": "LEUCINE-RICH COLIPASE-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH COLIPASE-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14580:SF0", "l": "MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24118:SF37", "l": "NF-KAPPA-B INHIBITOR EPSILON", "d": [], "t": []}], "preferred_name": "NF-KAPPA-B INHIBITOR EPSILON", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45638:SF8", "l": "CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-3", "d": [], "t": []}], "preferred_name": "CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:769", "l": "Tetratricopeptide repeat domain containing", "d": [], "t": []}], "preferred_name": "Tetratricopeptide repeat domain containing", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3835", "l": "Cap 'n' collar bZIP transcription factors", "d": ["In mammals, the cap 'n' collar (CNC) family of transcription factors comprises six proteins: NFE, NFE2L1, NFE2L2, NFE2L3, BACH1 and BACH2. All six proteins share a common CNC sequence adjacent to a DNA binding domain. CNC proteins bind a common DNA motif termed the antioxidant response element (ARE). Mammalian CNC transcription factors cannot regulate gene expression as monomers. Canonically, these proteins heterodimerize with small MAF transcription factors (MAFF, MAFK, and MAFG) to regulate transcription."], "t": []}], "preferred_name": "Cap 'n' collar bZIP transcription factors", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18914:SF21", "l": "CATENIN ALPHA-3", "d": [], "t": []}], "preferred_name": "CATENIN ALPHA-3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16208:SF1", "l": "SYNTAPHILIN", "d": [], "t": []}], "preferred_name": "SYNTAPHILIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31698:SF5", "l": "LYSOZYME G-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "LYSOZYME G-LIKE PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24064:SF432", "l": "SOLUTE CARRIER FAMILY 22 MEMBER 2", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 22 MEMBER 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12822", "l": "PROTEIN YIPF", "d": [], "t": []}], "preferred_name": "PROTEIN YIPF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12241:SF91", "l": "TUBULIN POLYGLUTAMYLASE TTLL13", "d": [], "t": []}], "preferred_name": "TUBULIN POLYGLUTAMYLASE TTLL13", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19232:SF1", "l": "CEREBELLAR DEGENERATION-RELATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "CEREBELLAR DEGENERATION-RELATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12848", "l": "REGULATORY-ASSOCIATED PROTEIN OF MTOR", "d": [], "t": []}], "preferred_name": "REGULATORY-ASSOCIATED PROTEIN OF MTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45905:SF3", "l": "ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3", "d": [], "t": []}], "preferred_name": "ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46303:SF3", "l": "CHORDIN-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "CHORDIN-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37365:SF1", "l": "TESTIS-EXPRESSED PROTEIN 44", "d": [], "t": []}], "preferred_name": "TESTIS-EXPRESSED PROTEIN 44", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12035:SF138", "l": "SIALIC ACID-BINDING IG-LIKE LECTIN 9", "d": [], "t": []}], "preferred_name": "SIALIC ACID-BINDING IG-LIKE LECTIN 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47979:SF73", "l": "RAS-RELATED PROTEIN RAB-4A", "d": [], "t": []}], "preferred_name": "RAS-RELATED PROTEIN RAB-4A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23349:SF70", "l": "TWIST-RELATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "TWIST-RELATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21178", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13723:SF197", "l": "A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 19", "d": [], "t": []}], "preferred_name": "A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10137:SF5", "l": "V-TYPE PROTON ATPASE SUBUNIT C 1", "d": [], "t": []}], "preferred_name": "V-TYPE PROTON ATPASE SUBUNIT C 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17488", "l": "NUCLEAR TRANSITION PROTEIN 2", "d": [], "t": []}], "preferred_name": "NUCLEAR TRANSITION PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15054", "l": "HISTIDINE-RICH CALCIUM-BINDING PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "HISTIDINE-RICH CALCIUM-BINDING PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3872", "l": "Egl-9 family hypoxia inducible factors", "d": ["The mammalian EGLN family contains three paralagous genes (EGLN1, EGLN2, and EGLN3) encoding prolyl hydroxylase isoforms that mediate the oxygen-dependent targeting of the transcription factor hypoxia inducible factor alpha to the proteosome."], "t": []}], "preferred_name": "Egl-9 family hypoxia inducible factors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11430:SF79", "l": "EPIDIDYMAL-SPECIFIC LIPOCALIN-10", "d": [], "t": []}], "preferred_name": "EPIDIDYMAL-SPECIFIC LIPOCALIN-10", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24416:SF106", "l": "INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR", "d": [], "t": []}], "preferred_name": "INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1121", "l": "Eukaryotic translation initiation factor 3", "d": [], "t": []}], "preferred_name": "Eukaryotic translation initiation factor 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28556:SF3", "l": "TRANSMEMBRANE PROTEIN 106A", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 106A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24403:SF82", "l": "ZINC FINGER-CONTAINING UBIQUITIN PEPTIDASE 1", "d": [], "t": []}], "preferred_name": "ZINC FINGER-CONTAINING UBIQUITIN PEPTIDASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47013:SF1", "l": "SPLICING FACTOR, ARGININE_SERINE-RICH 19", "d": [], "t": []}], "preferred_name": "SPLICING FACTOR, ARGININE_SERINE-RICH 19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19305:SF5", "l": "SYNAPTOSOMAL-ASSOCIATED PROTEIN 25", "d": [], "t": []}], "preferred_name": "SYNAPTOSOMAL-ASSOCIATED PROTEIN 25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13439", "l": "CT120 PROTEIN", "d": [], "t": []}], "preferred_name": "CT120 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2263", "l": "Small MAF bZIP transcription factor family", "d": [], "t": []}], "preferred_name": "Small MAF bZIP transcription factor family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12137:SF2", "l": "CARBOHYDRATE SULFOTRANSFERASE 10", "d": [], "t": []}], "preferred_name": "CARBOHYDRATE SULFOTRANSFERASE 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10555", "l": "SORTING NEXIN", "d": [], "t": []}], "preferred_name": "SORTING NEXIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46025:SF1", "l": "XYLOSYLTRANSFERASE 2", "d": [], "t": []}], "preferred_name": "XYLOSYLTRANSFERASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12566:SF9", "l": "CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28554", "l": "39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24092:SF50", "l": "PHOSPHOLIPID-TRANSPORTING ATPASE IIB-RELATED", "d": [], "t": []}], "preferred_name": "PHOSPHOLIPID-TRANSPORTING ATPASE IIB-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24291", "l": "CYTOCHROME P450 FAMILY 4", "d": [], "t": []}], "preferred_name": "CYTOCHROME P450 FAMILY 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14972:SF7", "l": "PROTEIN FAM117A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM117A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13105:SF22", "l": "MYELOID LEUKEMIA FACTOR 1", "d": [], "t": []}], "preferred_name": "MYELOID LEUKEMIA FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10217:SF468", "l": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 6", "d": [], "t": []}], "preferred_name": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11733:SF133", "l": "PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX", "d": [], "t": []}], "preferred_name": "PHOSPHATE-REGULATING NEUTRAL ENDOPEPTIDASE PHEX", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36296:SF1", "l": "CHROMOSOME 2 OPEN READING FRAME 80", "d": [], "t": []}], "preferred_name": "CHROMOSOME 2 OPEN READING FRAME 80", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13872:SF43", "l": "DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A", "d": [], "t": []}], "preferred_name": "DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12952:SF0", "l": "PROTEIN SYS1 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN SYS1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21330", "l": "E3 SUMO-PROTEIN LIGASE NSE2", "d": [], "t": []}], "preferred_name": "E3 SUMO-PROTEIN LIGASE NSE2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13152", "l": "TFIIH, POLYPEPTIDE 4", "d": [], "t": []}], "preferred_name": "TFIIH, POLYPEPTIDE 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31931", "l": "PROTEIN CHURCHILL", "d": [], "t": []}], "preferred_name": "PROTEIN CHURCHILL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32005:SF1", "l": "TRANSMEMBRANE PROTEIN 178B", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 178B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3371", "l": "DNA/RNA methyltransferases", "d": [], "t": []}], "preferred_name": "DNA/RNA methyltransferases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:630", "l": "Leukocyte immunoglobulin like receptors", "d": ["The leukocyte immunoglobulin-like receptors (LILR) are a family of receptors possessing extracellular immunoglobulin domains. They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. The human genes encoding these receptors are found in a gene cluster at chromosomal region 19q13.4."], "t": []}], "preferred_name": "Leukocyte immunoglobulin like receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:562", "l": "Gamma-aminobutyric acid (GABA) receptors", "d": ["The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory neurotransmitter in the vertebrate central nervous system. There are two classes of GABA receptors: GABA A and GABA B.  GABA A receptors are ligand-gated ion channels (also known as ionotropic receptors), whereas GABA B receptors are G protein-coupled receptors (also known as metabotropic receptors )."], "t": []}], "preferred_name": "Gamma-aminobutyric acid (GABA) receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22652", "l": "NUCLEOPORIN NUP43", "d": [], "t": []}], "preferred_name": "NUCLEOPORIN NUP43", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12247:SF77", "l": "SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1", "d": [], "t": []}], "preferred_name": "SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21481:SF0", "l": "PROTEIN CLEC16A", "d": [], "t": []}], "preferred_name": "PROTEIN CLEC16A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12566:SF7", "l": "CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3", "d": [], "t": []}], "preferred_name": "CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23239:SF97", "l": "KERATIN, TYPE I CUTICULAR HA1", "d": [], "t": []}], "preferred_name": "KERATIN, TYPE I CUTICULAR HA1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45639:SF3", "l": "HYPOXIA UP-REGULATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "HYPOXIA UP-REGULATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45960:SF5", "l": "GRB2-ASSOCIATED-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "GRB2-ASSOCIATED-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1026", "l": "MutS homologs", "d": ["Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse effects of damage to the genome. It involves the correction of mismatched base pairs that have been missed by the proofreading element ( Klenow fragment ) of the DNA polymerase complex. The post-replicative Mismatch Repair System (MMRS) of Escherichia coli involves MutS (Mutator S), MutL and MutH proteins, and acts to correct point mutations or small insertion/deletion loops produced during DNA replication. MutS and MutL are involved in preventing recombination between partially homologous DNA sequences. The assembly of MMRS is initiated by MutS, which recognizes and binds to mispaired nucleotides and allows further action of MutL and MutH to eliminate a portion of newly synthesized DNA strand containing the mispaired base. MutS can also collaborate with methyltransferases in the repair of O(6)-methylguanine damage, which would otherwise pair with thymine during replication to create an O(6)mG:T mismatch. MutS exists as a dimer, where the two monomers have different conformations and form a heterodimer at the structural level. Only one monomer recognises the mismatch specifically and has ADP bound. Non-specific major groove DNA-binding domains from both monomers embrace the DNA in a clamp-like structure. Mismatch binding induces ATP uptake and a conformational change in the MutS protein, resulting in a clamp that translocates on DNA.  MutS is a modular protein with a complex structure, and is composed of:  N-terminal mismatch-recognition domain, which is similar in structure to tRNA endonuclease.  Connector domain, which is similar in structure to Holliday junction resolvase ruvC.  Core domain, which is composed of two separate subdomains that join together to form a helical bundle; from within the core domain, two helices act as levers that extend towards (but do not touch) the DNA.  Clamp domain, which is inserted between the two subdomains of the core domain at the top of the lever helices; the clamp domain has a beta-sheet structure.  ATPase domain (connected to the core domain), which has a classical Walker A motif.  HTH (helix-turn-helix) domain, which is involved in dimer contacts.   Homologues of MutS have been found in many species including eukaryotes (MSH 1, 2, 3, 4, 5, and 6 proteins), archaea and bacteria, and together these proteins have been grouped into the MutS family. Although many of these proteins have similar activities to the E. coli MutS, there is significant diversity of function among the MutS family members. This diversity is even seen within species, where many species encode multiple MutS homologues with distinct functions. Inter-species homologues may have arisen through frequent ancient horizontal gene transfer of MutS (and MutL) from bacteria to archaea and eukaryotes via endosymbiotic ancestors of mitochondria and chloroplasts.   ."], "t": []}], "preferred_name": "MutS homologs", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17920", "l": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13723:SF147", "l": "ADAMTS-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "ADAMTS-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14491:SF2", "l": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45937", "l": "ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12232:SF3", "l": "SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48001:SF43", "l": "OLFACTORY RECEPTOR 1N1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 1N1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16056:SF2", "l": "TESTIS-EXPRESSED PROTEIN 10", "d": [], "t": []}], "preferred_name": "TESTIS-EXPRESSED PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15505:SF1", "l": "BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG", "d": [], "t": []}], "preferred_name": "BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46314:SF2", "l": "SOLUTE CARRIER FAMILY 25 MEMBER 44", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 25 MEMBER 44", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46940:SF1", "l": "NKAP DOMAIN CONTAINING 1", "d": [], "t": []}], "preferred_name": "NKAP DOMAIN CONTAINING 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10185", "l": "PHOSPHOLIPASE D - RELATED", "d": [], "t": []}], "preferred_name": "PHOSPHOLIPASE D - RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11247:SF8", "l": "PALMITOYL-PROTEIN THIOESTERASE 1", "d": [], "t": []}], "preferred_name": "PALMITOYL-PROTEIN THIOESTERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15025:SF6", "l": "VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-6 SUBUNIT", "d": [], "t": []}], "preferred_name": "VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-6 SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11537:SF265", "l": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 2", "d": [], "t": []}], "preferred_name": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13085:SF3", "l": "SIGNAL PEPTIDASE COMPLEX SUBUNIT 2", "d": [], "t": []}], "preferred_name": "SIGNAL PEPTIDASE COMPLEX SUBUNIT 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45884:SF3", "l": "N-ACETYLTRANSFERASE ESCO2", "d": [], "t": []}], "preferred_name": "N-ACETYLTRANSFERASE ESCO2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21082", "l": "PROTEIN INTURNED", "d": [], "t": []}], "preferred_name": "PROTEIN INTURNED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13084", "l": "T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED", "d": [], "t": []}], "preferred_name": "T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11814:SF11", "l": "TESTIS ANION TRANSPORTER 1", "d": [], "t": []}], "preferred_name": "TESTIS ANION TRANSPORTER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24232:SF20", "l": "PROTEINASE-ACTIVATED RECEPTOR 1", "d": [], "t": []}], "preferred_name": "PROTEINASE-ACTIVATED RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32026:SF10", "l": "METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED", "d": [], "t": []}], "preferred_name": "METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10569:SF2", "l": "GLYCOGEN DEBRANCHING ENZYME", "d": [], "t": []}], "preferred_name": "GLYCOGEN DEBRANCHING ENZYME", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31021", "l": "ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1", "d": [], "t": []}], "preferred_name": "ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45664:SF13", "l": "HOMEOBOX PROTEIN HOX-A3", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN HOX-A3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:305", "l": "Aquaporins", "d": ["Aquaporins are integral membrane proteins from a larger family of major intrinsic proteins (MIP) that form pores in the membrane of biological cells.  Genetic defects involving aquaporin genes have been associated with several human diseases. The 2003 Nobel Prize in Chemistry was awarded jointly to Peter Agre for the discovery of aquaporins, and Roderick MacKinnon for his work on the structure and mechanism of potassium channels. The plasma membranes of a variety of different animal and plant cells contain aquaporins through which water can flow more rapidly inside the cell than by diffusing through the phospholipid bilayer."], "t": []}], "preferred_name": "Aquaporins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF161", "l": "SERPIN B13", "d": [], "t": []}], "preferred_name": "SERPIN B13", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21032:SF0", "l": "G PATCH DOMAIN-CONTAINING PROTEIN 11", "d": [], "t": []}], "preferred_name": "G PATCH DOMAIN-CONTAINING PROTEIN 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13554", "l": "26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED", "d": [], "t": []}], "preferred_name": "26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13238:SF0", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12126", "l": "NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:912", "l": "Adhesion G protein-coupled receptors, subfamily B", "d": [], "t": []}], "preferred_name": "Adhesion G protein-coupled receptors, subfamily B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22619", "l": "ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6", "d": [], "t": []}], "preferred_name": "ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45781:SF2", "l": "TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 4", "d": [], "t": []}], "preferred_name": "TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12563:SF17", "l": "DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10104:SF17", "l": "STATHMIN-3", "d": [], "t": []}], "preferred_name": "STATHMIN-3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10628:SF22", "l": "SIALIDASE-4", "d": [], "t": []}], "preferred_name": "SIALIDASE-4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10799:SF819", "l": "GLOBAL TRANSCRIPTION ACTIVATOR SNF2L1-RELATED", "d": [], "t": []}], "preferred_name": "GLOBAL TRANSCRIPTION ACTIVATOR SNF2L1-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23026:SF90", "l": "IODOTYROSINE DEIODINASE 1", "d": [], "t": []}], "preferred_name": "IODOTYROSINE DEIODINASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31883:SF1", "l": "PROTEIN FRG2-LIKE-2", "d": [], "t": []}], "preferred_name": "PROTEIN FRG2-LIKE-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11778:SF23", "l": "SERINE--TRNA LIGASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "SERINE--TRNA LIGASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43725", "l": "UDP-GLUCOSE 4-EPIMERASE", "d": [], "t": []}], "preferred_name": "UDP-GLUCOSE 4-EPIMERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16983:SF12", "l": "GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED HIGH DENSITY LIPOPROTEIN-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18956:SF6", "l": "HYALURONAN MEDIATED MOTILITY RECEPTOR", "d": [], "t": []}], "preferred_name": "HYALURONAN MEDIATED MOTILITY RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14401:SF6", "l": "CENTROMERE PROTEIN K", "d": [], "t": []}], "preferred_name": "CENTROMERE PROTEIN K", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15116:SF15", "l": "DNA-BINDING PROTEIN SATB2", "d": [], "t": []}], "preferred_name": "DNA-BINDING PROTEIN SATB2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1501", "l": "U2 small nuclear ribonucleoprotein", "d": ["The U2 snRNP complex is involved in pre-mRNA splicing events. U2 snRNP plays a role in the recognition of the 3 prime splice site and the branch site in introns."], "t": []}], "preferred_name": "U2 small nuclear ribonucleoprotein", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1430", "l": "G protein subunits beta", "d": ["Guanine nucleotide binding proteins (G proteins) are membrane-associated, heterotrimeric proteins composed of three subunits: alpha, beta and gamma. This entry consists of the G protein beta subunit, which assumes a barrel-shaped beta-propeller structure containing WD-40 repeats preceded by an N-terminal alpha helix. The beta subunit forms a stable dimer with the gamma subunit. The alpha subunit only contacts the beta subunit in the dimer, lying on the opposite face from the gamma subunit."], "t": []}], "preferred_name": "G protein subunits beta", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21610:SF9", "l": "VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8", "d": [], "t": []}], "preferred_name": "VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16083:SF39", "l": "E3 UBIQUITIN-PROTEIN LIGASE LRSAM1", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE LRSAM1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26451:SF233", "l": "OLFACTORY RECEPTOR 4E1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 4E1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14972:SF3", "l": "GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN", "d": [], "t": []}], "preferred_name": "GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23036:SF96", "l": "INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-31 RECEPTOR SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19855", "l": "WD40 REPEAT PROTEIN 12, 37", "d": [], "t": []}], "preferred_name": "WD40 REPEAT PROTEIN 12, 37", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20859:SF54", "l": "INTERFERON ALPHA_BETA RECEPTOR 1", "d": [], "t": []}], "preferred_name": "INTERFERON ALPHA_BETA RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43684:SF5", "l": "CHROMODOMAIN Y-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "CHROMODOMAIN Y-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15703:SF3", "l": "GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1", "d": [], "t": []}], "preferred_name": "GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10551:SF1", "l": "FASCIN-3", "d": [], "t": []}], "preferred_name": "FASCIN-3", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12800", "l": "CDC37-RELATED", "d": [], "t": []}], "preferred_name": "CDC37-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10558:SF2", "l": "SOMATOSTATIN", "d": [], "t": []}], "preferred_name": "SOMATOSTATIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11035:SF16", "l": "VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4", "d": [], "t": []}], "preferred_name": "VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12910", "l": "NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24388:SF69", "l": "ZINC FINGER PROTEIN PLAG1", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN PLAG1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46987", "l": "NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15741", "l": "BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR", "d": [], "t": []}], "preferred_name": "BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11037:SF13", "l": "UPSTREAM-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "UPSTREAM-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18947:SF31", "l": "PROTEIN DAPLE", "d": [], "t": []}], "preferred_name": "PROTEIN DAPLE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48431", "l": "TRANSMEMBRANE PROTEIN 250", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 250", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18919:SF156", "l": "ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15741:SF25", "l": "MAX-LIKE PROTEIN X", "d": [], "t": []}], "preferred_name": "MAX-LIKE PROTEIN X", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12015:SF73", "l": "C-C MOTIF CHEMOKINE 26", "d": [], "t": []}], "preferred_name": "C-C MOTIF CHEMOKINE 26", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10865:SF5", "l": "METASTASIS-ASSOCIATED PROTEIN MTA1", "d": [], "t": []}], "preferred_name": "METASTASIS-ASSOCIATED PROTEIN MTA1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47904:SF1", "l": "NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3", "d": [], "t": []}], "preferred_name": "NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19432", "l": "SUGAR TRANSPORTER", "d": [], "t": []}], "preferred_name": "SUGAR TRANSPORTER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16253:SF0", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 22", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46436", "l": "CENTROSOMAL PROTEIN OF 76 KDA", "d": [], "t": []}], "preferred_name": "CENTROSOMAL PROTEIN OF 76 KDA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10361:SF29", "l": "SODIUM_BILE ACID COTRANSPORTER 5", "d": [], "t": []}], "preferred_name": "SODIUM_BILE ACID COTRANSPORTER 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16551:SF4", "l": "AGOUTI-RELATED PROTEIN", "d": [], "t": []}], "preferred_name": "AGOUTI-RELATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12441:SF10", "l": "ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12050:SF3", "l": "LEPTIN RECEPTOR GENE-RELATED PROTEIN", "d": [], "t": []}], "preferred_name": "LEPTIN RECEPTOR GENE-RELATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10073:SF54", "l": "PMS1 PROTEIN HOMOLOG 1", "d": [], "t": []}], "preferred_name": "PMS1 PROTEIN HOMOLOG 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43788:SF6", "l": "DNA HELICASE B", "d": [], "t": []}], "preferred_name": "DNA HELICASE B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11071:SF11", "l": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C", "d": [], "t": []}], "preferred_name": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13624:SF4", "l": "TRANSMEMBRANE PROTEIN 161A", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 161A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35156:SF1", "l": "TESTIS-EXPRESSED PROTEIN 52", "d": [], "t": []}], "preferred_name": "TESTIS-EXPRESSED PROTEIN 52", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10438:SF107", "l": "THIOREDOXIN DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "THIOREDOXIN DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF735", "l": "OLFACTORY RECEPTOR 10J6-RELATED", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 10J6-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1439", "l": "M13 metallopeptidases", "d": ["These genes encode zinc dependent metallopeptidases in which two of the zinc ligands are histidines in a 'HEXXH' motif."], "t": []}], "preferred_name": "M13 metallopeptidases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13369:SF0", "l": "GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12466", "l": "CDC73 DOMAIN PROTEIN", "d": [], "t": []}], "preferred_name": "CDC73 DOMAIN PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10276", "l": "CORE-BINDING FACTOR, BETA SUBUNIT", "d": [], "t": []}], "preferred_name": "CORE-BINDING FACTOR, BETA SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24413:SF97", "l": "SPECKLE-TYPE POZ PROTEIN", "d": [], "t": []}], "preferred_name": "SPECKLE-TYPE POZ PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:85", "l": "Zinc fingers MIZ-type", "d": ["In molecular biology the MIZ-type zinc finger domain is a zinc finger-containing protein with homology to the yeast protein, Nfi-1. Miz1 is a sequence specific DNA binding protein that can function as a positive-acting transcription factor. Miz1 binds to the homeobox protein Msx2, enhancing the specific DNA-binding ability of Msx2. Other proteins containing this domain include the human pias family (protein inhibitor of activated STAT protein). The name MIZ is derived from M sx- i nteracting- z inc finger. The crystal structure of S. cerevisiae sumo e3 ligase siz1 containing this domain has been solved."], "t": []}], "preferred_name": "Zinc fingers MIZ-type", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47395", "l": "BPI FOLD-CONTAINING FAMILY B MEMBER 1", "d": [], "t": []}], "preferred_name": "BPI FOLD-CONTAINING FAMILY B MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14817", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 15", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:676", "l": "Pellino E3 ubiquitin protein ligases", "d": [], "t": []}], "preferred_name": "Pellino E3 ubiquitin protein ligases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24332:SF16", "l": "HOMEOBOX PROTEIN CDX-1", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN CDX-1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12385:SF13", "l": "CHOLINE TRANSPORTER-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "CHOLINE TRANSPORTER-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF470", "l": "IMMUNOGLOBULIN LAMBDA VARIABLE 1-51", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN LAMBDA VARIABLE 1-51", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:457", "l": "BRICHOS domain containing", "d": ["The BRICHOS family consists of a variety of proteins linked to major diseases, each containing a 100 amino acid BRICHOS domain that is thought to have a chaperone function."], "t": []}], "preferred_name": "BRICHOS domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10127", "l": "DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING", "d": [], "t": []}], "preferred_name": "DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46805:SF1", "l": "FORKHEAD BOX PROTEIN J1", "d": [], "t": []}], "preferred_name": "FORKHEAD BOX PROTEIN J1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16423:SF7", "l": "NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2", "d": [], "t": []}], "preferred_name": "NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43015", "l": "D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31804:SF3", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16193:SF0", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 27", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 27", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47086", "l": "BTB DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "BTB DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24056:SF177", "l": "CYCLIN-DEPENDENT KINASE-LIKE 3", "d": [], "t": []}], "preferred_name": "CYCLIN-DEPENDENT KINASE-LIKE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11610:SF2", "l": "HEPATIC TRIACYLGLYCEROL LIPASE", "d": [], "t": []}], "preferred_name": "HEPATIC TRIACYLGLYCEROL LIPASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16083:SF8", "l": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10533:SF5", "l": "PRO-NEUROPEPTIDE Y", "d": [], "t": []}], "preferred_name": "PRO-NEUROPEPTIDE Y", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18945:SF393", "l": "GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4", "d": [], "t": []}], "preferred_name": "GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11848:SF232", "l": "LEFT-RIGHT DETERMINATION FACTOR 2", "d": [], "t": []}], "preferred_name": "LEFT-RIGHT DETERMINATION FACTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44340", "l": "DNAJ HOMOLOG SUBFAMILY C MEMBER 10", "d": [], "t": []}], "preferred_name": "DNAJ HOMOLOG SUBFAMILY C MEMBER 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:752", "l": "Solute carrier families", "d": ["The solute carrier (SLC) group of membrane transport proteins include over 400 members organized into 66 families. Most members of the SLC group are located in the cell membrane."], "t": []}], "preferred_name": "Solute carrier families", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20883", "l": "PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1", "d": [], "t": []}], "preferred_name": "PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3715", "l": "Drebrin family", "d": ["Drebrin and drebrin like (often called actin-binding protein 1, ABP1) encode multidomain proteins that includes an actin-depolymerising factor homology (ADF-H) domain in their N-terminus. They interact with actin filaments and regulate the activities of other proteins during various actin-dependent processes."], "t": []}], "preferred_name": "Drebrin family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13429:SF11", "l": "FERM DOMAIN-CONTAINING PROTEIN 6", "d": [], "t": []}], "preferred_name": "FERM DOMAIN-CONTAINING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24068", "l": "UBIQUITIN-CONJUGATING ENZYME E2", "d": [], "t": []}], "preferred_name": "UBIQUITIN-CONJUGATING ENZYME E2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46723", "l": "LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15936", "l": "GUANINE NUCLEOTIDE-BINDING PROTEIN G I /G S /G O  GAMMA-13 SUBUNIT", "d": [], "t": []}], "preferred_name": "GUANINE NUCLEOTIDE-BINDING PROTEIN G I /G S /G O  GAMMA-13 SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1854", "l": "Iron-sulfur assembly components", "d": [], "t": []}], "preferred_name": "Iron-sulfur assembly components", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11467:SF182", "l": "HISTONE H1.0", "d": [], "t": []}], "preferred_name": "HISTONE H1.0", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17613:SF8", "l": "TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE AND COILED-COIL DOMAIN PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23182:SF3", "l": "BREAKPOINT CLUSTER REGION PROTEIN", "d": [], "t": []}], "preferred_name": "BREAKPOINT CLUSTER REGION PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14319:SF6", "l": "TRANSMEMBRANE PROTEIN 8B", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 8B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15706", "l": "SH3 MULTIPLE DOMAIN", "d": [], "t": []}], "preferred_name": "SH3 MULTIPLE DOMAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15276", "l": "H4 D10S170  PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "H4 D10S170  PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28498:SF1", "l": "ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7", "d": [], "t": []}], "preferred_name": "ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:589", "l": "Immunoglobulin superfamily domain containing", "d": ["The immunoglobulin superfamily (IgSF) is a large group of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared structural features with immunoglobulins (also known as antibodies); they all possess a domain known as an immunoglobulin domain or fold. Members of the IgSF include cell surface antigen receptors, co-receptors and co-stimulatory molecules of the immune system, molecules involved in antigen presentation to lymphocytes, cell adhesion molecules, certain cytokine receptors and intracellular muscle proteins. They are commonly associated with roles in the immune system."], "t": []}], "preferred_name": "Immunoglobulin superfamily domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1851", "l": "CSAG family", "d": [], "t": []}], "preferred_name": "CSAG family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3765", "l": "Mitogen-activated protein kinase 3 and 1 (ERK1/2) family", "d": ["The evolutionarily conserved kinases MAPK1 and MAPK3, also known as ERK2 and ERK1 respectively, constituye one of the four subfamilies of conventional MAPKs. Activation of each group of conventional MAPKs depends on a set of two upstream, evolutionarily conserved, sequentially acting kinases. MAPK1/3 are activated by growth factors, ligands for heterotrimeric G protein-coupled receptors (GPCRs), cytokines, osmotic stress, microtubule disorganization, and in response to insulin. Their main initiating kinases (MAP3Ks) are members of the RAF family, which include serine/threonine-protein kinases ARAF, BRAF and RAF1 (CRAF), and are often activated as a result of their interaction with active GTP-bound RAS proteins. Once activated, RAF kinases phosphorylate and activate components of the MAP2K module, such as MAP2K1 (MEK1) and MAP2K2 (MEK2), which in turn activate MAPK1 and MAPK3 through phosphorylation of both tyrosine and threonine residues present in a conserved tripeptide motif (Thr-Glu-Tyr) within their activation loop. Through the phosphorylation of their targets, MAPK1 and MAPK3 are involved in a wide variety of cellular processes including proliferation, inflammation, and cellular metabolism."], "t": []}], "preferred_name": "Mitogen-activated protein kinase 3 and 1 (ERK1/2) family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43311:SF2", "l": "GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED", "d": [], "t": []}], "preferred_name": "GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10182:SF11", "l": "CALCIUM-BINDING PROTEIN 39", "d": [], "t": []}], "preferred_name": "CALCIUM-BINDING PROTEIN 39", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47278", "l": "GLUTATHIONE HYDROLASE 6", "d": [], "t": []}], "preferred_name": "GLUTATHIONE HYDROLASE 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23335:SF9", "l": "CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2", "d": [], "t": []}], "preferred_name": "CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46232:SF2", "l": "SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1", "d": [], "t": []}], "preferred_name": "SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35826", "l": "PROTEIN ATP6V1FNB-LIKE", "d": [], "t": []}], "preferred_name": "PROTEIN ATP6V1FNB-LIKE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46071", "l": "ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16515:SF22", "l": "HISTONE-LYSINE N-METHYLTRANSFERASE PRDM6-RELATED", "d": [], "t": []}], "preferred_name": "HISTONE-LYSINE N-METHYLTRANSFERASE PRDM6-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24343:SF181", "l": "SNF-RELATED SERINE_THREONINE-PROTEIN KINASE", "d": [], "t": []}], "preferred_name": "SNF-RELATED SERINE_THREONINE-PROTEIN KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43721:SF3", "l": "GTP-BINDING PROTEIN 2", "d": [], "t": []}], "preferred_name": "GTP-BINDING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1171", "l": "SCF complex", "d": ["Skp, Cullin, F-box containing complex (or SCF complex ) is a multi-protein E3 ubiquitin ligase complex catalyzing the ubiquitination of proteins destined for proteasomal degradation. It has important roles in the ubiquitination of proteins involved in the cell cycle and also marks various other cellular proteins for destruction.   Core Components  SCF contains three core subunits, and a number of less critical components:   F-box protein ( e.g. Cdc4 ) â€' Contributes to the specificity of SCF by aggregating to target proteins independently of the complex and then binding to the Skp1 component, thus allowing the protein to be brought into proximity with the functional E2 protein. The F-box is also essential in regulating SCF activity during the course of the cell-cycle. SCF levels are thought to remain constant throughout the cell-cycle. Instead, F-box affinity for protein substrates is regulated through cdk/cyclin mediated phosphorylation of target proteins.   Skp1 â€' Skp1 is a bridging protein and forms part of the horseshoe-shaped complex in tandem with cullin (cul1). Skp1 is essential in the recognition and binding of the F-box.   Cullin ( CUL1 ) â€' CUL1 forms the major structural scaffold of the SCF complex and links the skp1 domain with the Rbx1 domain.   RBX1 â€' Rbx1 contains a small zinc-binding domain called the RING Finger, to which the E2-ubiquitin conjugate binds, allowing the transferral of the ubiquitin to a lysine residue on the target protein.   SCF and Cell Cycle Regulation  Progression through the cell cycle in eukaryotes is regulated through synthesisdephosphorylation of cell-cycle-regulating proteins. Two ubiquitin ligases are crucial in the cell cycle. The anaphase-promoting complex or cyclosome ( APC/C ) controls the metaphase â€' anaphase transition when bound to its substrate-specific activating subunit Cdc20 : this complex ubiquitinylates the separase -inhibiting protein securin, paving the way for separase to break cohesin and thus separate the sister chromatids at the centromere. APC/C with another activating subunit, Cdh1, is active in G1 phase and controls levels of the mitosis-regulating B-type cyclins.  SCF controls the transitions between G1/S and G2/M phases. Two F-box-protein-bound SCF complexes (SCF- Skp2 and SCF- β-TrCP ), are most well studied among over 70 F-box proteins identified in humans. SCF-Skp2 mainly ubiquitinates and degrades cyclin-dependent kinase inhibitors (CKIs) such as p27 and p21 as well as the G1-/S-specific cyclin E, in vivo and in vitro. Therefore, SCF-Skp2 promotes cell-cycle progression and cell growth. On the other hand, SCF-βTrCP promotes proteolysis of Emi1, an APC/C-Cdh1 inhibitor, and Wee1, a Cdk1 inhibitor, in early mitosis via phosphorylation at their degron (the amino acid motif DSGXXS, where X can be any amino acid) by kinases such as Polo-like kinase 1 (Plk1) and Cdk1â€'cyclin B. SCF-βTrCP and APC/C control each other to regulate timely progression through the cell cycle. Lists of substrates of SCF-Skp2 and -βTrCP are still growing.  SCF and Plant Hormone Signaling  In plants, the plant hormone auxin stimulates binding of SCF-TIR1 to the AUX/IAA repressor and then the degradation of the repressor, resulting in the activation of auxin-responsive genes. The TIR1 F-box protein acts as an auxin receptor and directly links reception of auxin to degradation of the Aux/IAA proteins. TIR1 (Transport Inhibitor Response 1) belongs to AFBs (Auxin Signaling F-box proteins).   In plants, the plant hormone Jasmonate allows binding between SCF-COI1 to the JAZ transcription factor. Degradation of the JAZ transcription factor allows for the transcription of the jasmonate responsive genes."], "t": []}], "preferred_name": "SCF complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1762", "l": "MicroRNA MIR365 family", "d": [], "t": []}], "preferred_name": "MicroRNA MIR365 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10075:SF52", "l": "NEXILIN", "d": [], "t": []}], "preferred_name": "NEXILIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:557", "l": "F-boxes", "d": ["F-box proteins are proteins containing at least one F-box domain. The first identified F-box protein is one of three components of the SCF complex, which mediates ubiquitination of proteins targeted for degradation by the proteasome. F-box proteins have also been associated with cellular functions such as signal transduction and regulation of the cell cycle. In plants, many F-box proteins are represented in gene networks broadly regulated by microRNA -mediated gene silencing via RNA interference. In human cells, in high-iron condition, two iron atoms stabilise the F-Box FBXL5 and then the complex mediates the ubiquitination of IRP2.  The F-box domain is a protein structural motif of about 50 amino acids that mediates protein–protein interactions. It was first identified in cyclin F. The F-box motif interacts directly with the SCF protein Skp1, and F-box domains commonly exist in proteins in concert with other protein–protein interaction motifs such as leucine-rich repeats and WD repeats, which are thought to mediate interactions with SCF substrates."], "t": []}], "preferred_name": "F-boxes", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45671", "l": "SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10270:SF216", "l": "TRANSCRIPTION FACTOR SOX-17", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR SOX-17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11716:SF8", "l": "GROUP IIF SECRETORY PHOSPHOLIPASE A2", "d": [], "t": []}], "preferred_name": "GROUP IIF SECRETORY PHOSPHOLIPASE A2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18945:SF764", "l": "5-HYDROXYTRYPTAMINE RECEPTOR 3E", "d": [], "t": []}], "preferred_name": "5-HYDROXYTRYPTAMINE RECEPTOR 3E", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24213:SF6", "l": "ACTIN-BINDING LIM PROTEIN 2", "d": [], "t": []}], "preferred_name": "ACTIN-BINDING LIM PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43161:SF9", "l": "SORBITOL DEHYDROGENASE", "d": [], "t": []}], "preferred_name": "SORBITOL DEHYDROGENASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24376:SF84", "l": "ZINC FINGER PROTEIN 521", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 521", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48050:SF12", "l": "UDP-GLUCURONOSYLTRANSFERASE 1A3-RELATED", "d": [], "t": []}], "preferred_name": "UDP-GLUCURONOSYLTRANSFERASE 1A3-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15377", "l": "TRANSCRIPTION ELONGATION REGULATOR 1", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION ELONGATION REGULATOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12307:SF7", "l": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48015:SF23", "l": "SERINE_THREONINE-PROTEIN KINASE 3", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10219:SF90", "l": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8", "d": [], "t": []}], "preferred_name": "PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15233", "l": "MITOCHONDRIAL PROTEOLIPID", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL PROTEOLIPID", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24388:SF100", "l": "ZINC FINGER PROTEIN 423", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 423", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23169:SF26", "l": "DESMOPLAKIN", "d": [], "t": []}], "preferred_name": "DESMOPLAKIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43191:SF2", "l": "RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24215", "l": "RHO-GTPASE-ACTIVATING PROTEIN LRG1", "d": [], "t": []}], "preferred_name": "RHO-GTPASE-ACTIVATING PROTEIN LRG1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13483:SF11", "l": "ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12963", "l": "THYROID RECEPTOR INTERACTING PROTEIN RELATED", "d": [], "t": []}], "preferred_name": "THYROID RECEPTOR INTERACTING PROTEIN RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3714", "l": "Glia maturation factor family", "d": ["Glia Maturation Factor (GMF) was first identified as a factor in brain extracts that could induce the differentiation of cultured glioblasts, gliomas, and neuroblastoma cells. Thus, GMF was studied for decades as a signaling factor controlling brain cell differentiation and function. GMF is now established as a regulator of the actin cytoskeleton with a unique role in remodeling actin network architecture. Conserved from yeast to mammals, GMF (encoded in human by the paralogs GMFB and GMFG) is a member of the ADF-H family of actin regulatory proteins. GMF does not bind actin, but does bind the Arp2/3 complex with high affinity. Through this association, GMF catalyzes the debranching of actin filament networks and inhibits actin nucleation by Arp2/3 complex."], "t": []}], "preferred_name": "Glia maturation factor family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11614:SF87", "l": "MONOGLYCERIDE LIPASE", "d": [], "t": []}], "preferred_name": "MONOGLYCERIDE LIPASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10201:SF270", "l": "STROMELYSIN-2", "d": [], "t": []}], "preferred_name": "STROMELYSIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22923:SF70", "l": "COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 6", "d": [], "t": []}], "preferred_name": "COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35022:SF28", "l": "PROTEIN KPLCE", "d": [], "t": []}], "preferred_name": "PROTEIN KPLCE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23159:SF17", "l": "ROOTLETIN", "d": [], "t": []}], "preferred_name": "ROOTLETIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12814", "l": "RNA-BINDING PROTEIN NOB1", "d": [], "t": []}], "preferred_name": "RNA-BINDING PROTEIN NOB1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45787:SF5", "l": "LIM DOMAIN TRANSCRIPTION FACTOR LMO4", "d": [], "t": []}], "preferred_name": "LIM DOMAIN TRANSCRIPTION FACTOR LMO4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11903:SF18", "l": "COLLAGEN TRIPLE HELIX REPEAT-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "COLLAGEN TRIPLE HELIX REPEAT-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16134:SF2", "l": "F-BOX_LRR-REPEAT PROTEIN 21-RELATED", "d": [], "t": []}], "preferred_name": "F-BOX_LRR-REPEAT PROTEIN 21-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31940:SF2", "l": "SMALL KINETOCHORE-ASSOCIATED PROTEIN", "d": [], "t": []}], "preferred_name": "SMALL KINETOCHORE-ASSOCIATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:76", "l": "Zinc fingers DHHC-type", "d": [], "t": []}], "preferred_name": "Zinc fingers DHHC-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11232", "l": "PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11738:SF192", "l": "KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR-LIKE PROTEIN KIR3DX1-RELATED", "d": [], "t": []}], "preferred_name": "KILLER CELL IMMUNOGLOBULIN-LIKE RECEPTOR-LIKE PROTEIN KIR3DX1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10901:SF12", "l": "LEIOMODIN-2", "d": [], "t": []}], "preferred_name": "LEIOMODIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1682", "l": "Metaxins", "d": [], "t": []}], "preferred_name": "Metaxins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21583", "l": "ELYS PROTEIN", "d": [], "t": []}], "preferred_name": "ELYS PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14383", "l": "SWAP-70 RECOMBINASE", "d": [], "t": []}], "preferred_name": "SWAP-70 RECOMBINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22948:SF4", "l": "TUDOR DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "TUDOR DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14359:SF6", "l": "PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE", "d": [], "t": []}], "preferred_name": "PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15663", "l": "COMM DOMAIN-CONTAINING PROTEIN 9", "d": [], "t": []}], "preferred_name": "COMM DOMAIN-CONTAINING PROTEIN 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11492:SF4", "l": "NUCLEAR FACTOR 1 B-TYPE", "d": [], "t": []}], "preferred_name": "NUCLEAR FACTOR 1 B-TYPE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15590", "l": "CX9C MOTIF-CONTAINING PROTEIN 4", "d": [], "t": []}], "preferred_name": "CX9C MOTIF-CONTAINING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16675:SF268", "l": "UL16-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "UL16-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1562", "l": "NSP adaptor proteins", "d": [], "t": []}], "preferred_name": "NSP adaptor proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22710:SF2", "l": "X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "X-RAY RADIATION RESISTANCE-ASSOCIATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14002:SF24", "l": "ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24208:SF96", "l": "LIM HOMEOBOX TRANSCRIPTION FACTOR 1-BETA", "d": [], "t": []}], "preferred_name": "LIM HOMEOBOX TRANSCRIPTION FACTOR 1-BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28584:SF3", "l": "PROTEIN FAM228B", "d": [], "t": []}], "preferred_name": "PROTEIN FAM228B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22906", "l": "PROPERDIN", "d": [], "t": []}], "preferred_name": "PROPERDIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47537:SF2", "l": "CUBILIN", "d": [], "t": []}], "preferred_name": "CUBILIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3421", "l": "CMGC kinase families", "d": [], "t": []}], "preferred_name": "CMGC kinase families", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12011:SF216", "l": "ADHESION G-PROTEIN COUPLED RECEPTOR D1", "d": [], "t": []}], "preferred_name": "ADHESION G-PROTEIN COUPLED RECEPTOR D1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24073:SF285", "l": "RAS-RELATED PROTEIN RAB-18", "d": [], "t": []}], "preferred_name": "RAS-RELATED PROTEIN RAB-18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15268", "l": "THRAP3/BCLAF1", "d": [], "t": []}], "preferred_name": "THRAP3/BCLAF1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10766:SF111", "l": "TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23334:SF69", "l": "CCAAT_ENHANCER-BINDING PROTEIN GAMMA", "d": [], "t": []}], "preferred_name": "CCAAT_ENHANCER-BINDING PROTEIN GAMMA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45939", "l": "PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED", "d": [], "t": []}], "preferred_name": "PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43289:SF14", "l": "LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE", "d": [], "t": []}], "preferred_name": "LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18945:SF385", "l": "NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4", "d": [], "t": []}], "preferred_name": "NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12315:SF0", "l": "7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME", "d": [], "t": []}], "preferred_name": "7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12281:SF6", "l": "DCN1-LIKE PROTEIN 5", "d": [], "t": []}], "preferred_name": "DCN1-LIKE PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28643", "l": "SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG", "d": [], "t": []}], "preferred_name": "SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11210:SF1", "l": "ANAPHASE-PROMOTING COMPLEX SUBUNIT 11", "d": [], "t": []}], "preferred_name": "ANAPHASE-PROMOTING COMPLEX SUBUNIT 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46075", "l": "CHIMERIN FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "CHIMERIN FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22597", "l": "POLYCOMB GROUP PROTEIN", "d": [], "t": []}], "preferred_name": "POLYCOMB GROUP PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:407", "l": "Arachidonate lipoxygenases", "d": ["Lipoxygenases ( EC 1.13.11.- ) are a family of iron -containing enzymes that catalyse the dioxygenation of polyunsaturated fatty acids in lipids containing a cis,cis-1,4- pentadiene structure. It catalyses the following reaction:   fatty acid + O 2 = fatty acid hydroperoxide   Lipoxygenases are found in plants, animals and fungi. Products of lipoxygenases are involved in diverse cell functions."], "t": []}], "preferred_name": "Arachidonate lipoxygenases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13636", "l": "TRANSMEMBRANE PROTEIN 258", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 258", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46019:SF4", "l": "BPI FOLD-CONTAINING FAMILY B MEMBER 4", "d": [], "t": []}], "preferred_name": "BPI FOLD-CONTAINING FAMILY B MEMBER 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16103:SF0", "l": "TRANSMEMBRANE PROTEIN 140", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 140", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46693", "l": "ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15", "d": [], "t": []}], "preferred_name": "ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31915:SF4", "l": "CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23285:SF5", "l": "RNA-BINDING PROTEIN MEX3B", "d": [], "t": []}], "preferred_name": "RNA-BINDING PROTEIN MEX3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16057", "l": "WINS1, 2 PROTEIN", "d": [], "t": []}], "preferred_name": "WINS1, 2 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3515", "l": "SAND domain containing", "d": ["The SAND domain is a conserved sequence motif found in a number of nuclear proteins, including the Sp100 family and NUDR (HGNC note - 'NUDR' is an alias and this gene has the approved symbol <a href='https://genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:14677'>DEAF1</a>). These are thought to play important roles in chromatin-dependent transcriptional regulation and are linked to many diseases. We have determined the three-dimensional (3D) structure of the SAND domain from Sp100b. The structure represents a novel alpha/beta fold, in which a conserved KDWK sequence motif is found within an alpha-helical, positively charged surface patch."], "t": []}], "preferred_name": "SAND domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42861:SF18", "l": "SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 2", "d": [], "t": []}], "preferred_name": "SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19359:SF150", "l": "CYTOCHROME B5", "d": [], "t": []}], "preferred_name": "CYTOCHROME B5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR40389", "l": "ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "ENDOGENOUS RETROVIRUS GROUP K MEMBER 24 GAG POLYPROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:106", "l": "Y-box binding proteins", "d": [], "t": []}], "preferred_name": "Y-box binding proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22959", "l": "PYM PROTEIN", "d": [], "t": []}], "preferred_name": "PYM PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10443:SF14", "l": "DIPEPTIDASE 3", "d": [], "t": []}], "preferred_name": "DIPEPTIDASE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31634", "l": "BLOC-1-RELATED COMPLEX SUBUNIT 5", "d": [], "t": []}], "preferred_name": "BLOC-1-RELATED COMPLEX SUBUNIT 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44337:SF6", "l": "CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19", "d": [], "t": []}], "preferred_name": "CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24229:SF7", "l": "MU-TYPE OPIOID RECEPTOR", "d": [], "t": []}], "preferred_name": "MU-TYPE OPIOID RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45806:SF1", "l": "SYNAPTOBREVIN HOMOLOG YKT6", "d": [], "t": []}], "preferred_name": "SYNAPTOBREVIN HOMOLOG YKT6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12620:SF33", "l": "U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR 35 KDA SUBUNIT-RELATED PROTEIN 1-RELATED", "d": [], "t": []}], "preferred_name": "U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR 35 KDA SUBUNIT-RELATED PROTEIN 1-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10410", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45928:SF3", "l": "SOLUTE CARRIER FAMILY 25 MEMBER 34", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 25 MEMBER 34", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13602", "l": "UPF0488 PROTEIN C8ORF33", "d": [], "t": []}], "preferred_name": "UPF0488 PROTEIN C8ORF33", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20844", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15712:SF8", "l": "ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 3", "d": [], "t": []}], "preferred_name": "ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11089", "l": "GTP-BINDING PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "GTP-BINDING PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15180:SF1", "l": "GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1", "d": [], "t": []}], "preferred_name": "GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21435", "l": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15256:SF6", "l": "INTEGRAL MEMBRANE PROTEIN DGCR2_IDD", "d": [], "t": []}], "preferred_name": "INTEGRAL MEMBRANE PROTEIN DGCR2_IDD", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24412:SF75", "l": "KELCH-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "KELCH-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32315", "l": "ADENINE PHOSPHORIBOSYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "ADENINE PHOSPHORIBOSYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36291:SF1", "l": "UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "UBAP1-MVB12-ASSOCIATED (UMA)-DOMAIN CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33442:SF1", "l": "TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE", "d": [], "t": []}], "preferred_name": "TRANS-3-HYDROXY-L-PROLINE DEHYDRATASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23205", "l": "SPLICING FACTOR 3A SUBUNIT 2", "d": [], "t": []}], "preferred_name": "SPLICING FACTOR 3A SUBUNIT 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12751:SF5", "l": "PHOSPHATASE AND ACTIN REGULATOR 2", "d": [], "t": []}], "preferred_name": "PHOSPHATASE AND ACTIN REGULATOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3666", "l": "Vasohibin family", "d": ["Vasohibins (VASH1 and VASH2) were originally identified as angiogenesis regulators. They have since been shown to act as SVBP-dependent tubulin detyrosinating enzymes."], "t": []}], "preferred_name": "Vasohibin family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35088:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 178", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 178", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3514", "l": "Membrane Attack complex", "d": ["The complement membrane attack complex (MAC) is classically known as a cytolytic effector of innate and adaptive immunity that forms pores in the plasma membrane of pathogens or targeted cells, leading to osmolysis."], "t": []}], "preferred_name": "Membrane Attack complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28448:SF1", "l": "UPF0728 PROTEIN C10ORF53", "d": [], "t": []}], "preferred_name": "UPF0728 PROTEIN C10ORF53", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16504", "l": "5'(3')-DEOXYRIBONUCLEOTIDASE", "d": [], "t": []}], "preferred_name": "5'(3')-DEOXYRIBONUCLEOTIDASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12329:SF2", "l": "BAG FAMILY MOLECULAR CHAPERONE REGULATOR 5", "d": [], "t": []}], "preferred_name": "BAG FAMILY MOLECULAR CHAPERONE REGULATOR 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46552:SF1", "l": "NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13615", "l": "GLYCOSYLTRANSFERASE-LIKE 1", "d": [], "t": []}], "preferred_name": "GLYCOSYLTRANSFERASE-LIKE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46227:SF4", "l": "GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2", "d": [], "t": []}], "preferred_name": "GLUTAMATE RECEPTOR-INTERACTING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12173:SF3", "l": "NEURTURIN", "d": [], "t": []}], "preferred_name": "NEURTURIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46016:SF2", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF125", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF125", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34439", "l": "CENTROBIN", "d": [], "t": []}], "preferred_name": "CENTROBIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10543:SF57", "l": "RETINOID ISOMEROHYDROLASE", "d": [], "t": []}], "preferred_name": "RETINOID ISOMEROHYDROLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11599:SF185", "l": "PROTEASOME SUBUNIT BETA TYPE-3", "d": [], "t": []}], "preferred_name": "PROTEASOME SUBUNIT BETA TYPE-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR38496:SF1", "l": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45776:SF4", "l": "MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR", "d": [], "t": []}], "preferred_name": "MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24416:SF49", "l": "VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3", "d": [], "t": []}], "preferred_name": "VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19282:SF249", "l": "TETRASPANIN-18", "d": [], "t": []}], "preferred_name": "TETRASPANIN-18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13064:SF2", "l": "TRANSMEMBRANE PROTEIN 9B", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 9B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13211:SF0", "l": "TELOMERASE CAJAL BODY PROTEIN 1", "d": [], "t": []}], "preferred_name": "TELOMERASE CAJAL BODY PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23262:SF244", "l": "KERATIN-ASSOCIATED PROTEIN 4-3", "d": [], "t": []}], "preferred_name": "KERATIN-ASSOCIATED PROTEIN 4-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24223:SF173", "l": "ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9", "d": [], "t": []}], "preferred_name": "ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10340:SF25", "l": "ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B", "d": [], "t": []}], "preferred_name": "ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16056", "l": "REGULATOR OF MICROTUBULE DYNAMICS PROTEIN", "d": [], "t": []}], "preferred_name": "REGULATOR OF MICROTUBULE DYNAMICS PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23042:SF52", "l": "BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "BASIC HELIX-LOOP-HELIX ARNT-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45865", "l": "E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14725", "l": "RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED", "d": [], "t": []}], "preferred_name": "RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17601:SF1", "l": "RAFTLIN-2", "d": [], "t": []}], "preferred_name": "RAFTLIN-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45752:SF23", "l": "VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8A", "d": [], "t": []}], "preferred_name": "VOLUME-REGULATED ANION CHANNEL SUBUNIT LRRC8A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13808", "l": "CBP/P300-RELATED", "d": [], "t": []}], "preferred_name": "CBP/P300-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10730:SF28", "l": "PROCOLLAGEN GALACTOSYLTRANSFERASE 1", "d": [], "t": []}], "preferred_name": "PROCOLLAGEN GALACTOSYLTRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19321", "l": "PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED", "d": [], "t": []}], "preferred_name": "PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11347:SF115", "l": "ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "ROD CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12149:SF9", "l": "FRUCTOSAMINE-3-KINASE", "d": [], "t": []}], "preferred_name": "FRUCTOSAMINE-3-KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24384:SF233", "l": "ZINC FINGER PROTEIN 331", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 331", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28656:SF1", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 153", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 153", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46785:SF1", "l": "VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B", "d": [], "t": []}], "preferred_name": "VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11782:SF33", "l": "ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2", "d": [], "t": []}], "preferred_name": "ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45632", "l": "LD33804P", "d": [], "t": []}], "preferred_name": "LD33804P", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2039", "l": "Myosin light chains, class 1", "d": [], "t": []}], "preferred_name": "Myosin light chains, class 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:994", "l": "Pyrin domain containing", "d": ["A pyrin domain is a protein domain and a subclass of protein motif known as the death fold; it allows a pyrin domain containing protein to interact with other proteins that contain a pyrin domain. It is also known as a PYD or PAAD/DAPIN domain, and is distantly evolutionarily related to the Death domain family of protein domains.[1][2][3]Proteins containing a pyrin domain are frequently involved in biological processes called inflammation and apoptosis.[4][5] Proteins that possess a pyrin domain include intracellular microbial sensors called NOD-like receptors, and proteins associated with their function, such as PYCARD and certain fish caspases."], "t": []}], "preferred_name": "Pyrin domain containing", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47316", "l": "FORKHEAD BOX PROTEIN H1", "d": [], "t": []}], "preferred_name": "FORKHEAD BOX PROTEIN H1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12951:SF5", "l": "PROTEIN UNC-119 HOMOLOG A", "d": [], "t": []}], "preferred_name": "PROTEIN UNC-119 HOMOLOG A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22774:SF15", "l": "BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3A", "d": [], "t": []}], "preferred_name": "BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 3A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12085:SF3", "l": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15268:SF4", "l": "BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1", "d": [], "t": []}], "preferred_name": "BCL-2-ASSOCIATED TRANSCRIPTION FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11453:SF127", "l": "SOLUTE CARRIER FAMILY 4 MEMBER 11", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 4 MEMBER 11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12856:SF0", "l": "GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1", "d": [], "t": []}], "preferred_name": "GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15351:SF4", "l": "ERLIN-2", "d": [], "t": []}], "preferred_name": "ERLIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23302:SF4", "l": "TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE CHANNEL-LIKE PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15564:SF2", "l": "BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3", "d": [], "t": []}], "preferred_name": "BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10910:SF106", "l": "ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32014", "l": "BCL-2-MODIFYING FACTOR", "d": [], "t": []}], "preferred_name": "BCL-2-MODIFYING FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3910", "l": "SERF domain containing", "d": ["All members of this group encode a Small EDRK-rich factor-like, N-terminal domain (InterPro IPR007513)."], "t": []}], "preferred_name": "SERF domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11157:SF16", "l": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 2", "d": [], "t": []}], "preferred_name": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10653:SF5", "l": "F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1", "d": [], "t": []}], "preferred_name": "F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11431:SF30", "l": "FERRITIN, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "FERRITIN, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31932", "l": "TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 1", "d": [], "t": []}], "preferred_name": "TUBULIN POLYGLUTAMYLASE COMPLEX SUBUNIT 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24219", "l": "LIM DOMAIN-CONTAINING PROTEIN JUB", "d": [], "t": []}], "preferred_name": "LIM DOMAIN-CONTAINING PROTEIN JUB", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46770:SF1", "l": "HOMEOBOX PROTEIN ORTHOPEDIA", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN ORTHOPEDIA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18934:SF119", "l": "ATP-DEPENDENT RNA HELICASE A", "d": [], "t": []}], "preferred_name": "ATP-DEPENDENT RNA HELICASE A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13144", "l": "TEX261 PROTEIN", "d": [], "t": []}], "preferred_name": "TEX261 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31542", "l": "39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10878:SF5", "l": "SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED", "d": [], "t": []}], "preferred_name": "SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43213", "l": "BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37333", "l": "LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH SINGLE-PASS MEMBRANE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23248:SF25", "l": "PHOSPHOLIPID SCRAMBLASE FAMILY MEMBER 5", "d": [], "t": []}], "preferred_name": "PHOSPHOLIPID SCRAMBLASE FAMILY MEMBER 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11006:SF51", "l": "HISTONE-ARGININE METHYLTRANSFERASE CARM1", "d": [], "t": []}], "preferred_name": "HISTONE-ARGININE METHYLTRANSFERASE CARM1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46149:SF1", "l": "GTP-BINDING PROTEIN RHES", "d": [], "t": []}], "preferred_name": "GTP-BINDING PROTEIN RHES", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13044:SF2", "l": "CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4", "d": [], "t": []}], "preferred_name": "CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15074", "l": "METHYL-CPG-BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "METHYL-CPG-BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10459:SF66", "l": "PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3", "d": [], "t": []}], "preferred_name": "PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12062:SF14", "l": "ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE C", "d": [], "t": []}], "preferred_name": "ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1248", "l": "PAR bZIP family", "d": ["PARbZip proteins represent a subfamily of circadian transcription factors belonging to the bZip family. They are transcriptionally controlled by the circadian molecular oscillator and are suspected to accomplish output functions of the clock. In turn, PARbZip proteins control expression of genes coding for enzymes involved in metabolism, but also expression of transcription factors which control the expression of these enzymes."], "t": []}], "preferred_name": "PAR bZIP family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15679:SF8", "l": "PCNA-ASSOCIATED FACTOR", "d": [], "t": []}], "preferred_name": "PCNA-ASSOCIATED FACTOR", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12787", "l": "RIBOSOMAL RNA-PROCESSING PROTEIN 8", "d": [], "t": []}], "preferred_name": "RIBOSOMAL RNA-PROCESSING PROTEIN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13354", "l": "ROUND SPERMATID BASIC PROTEIN 1", "d": [], "t": []}], "preferred_name": "ROUND SPERMATID BASIC PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11347:SF135", "l": "CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4C", "d": [], "t": []}], "preferred_name": "CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13043:SF1", "l": "EXOCYST COMPLEX COMPONENT 2", "d": [], "t": []}], "preferred_name": "EXOCYST COMPLEX COMPONENT 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36464:SF1", "l": "PROTEIN BEAN1", "d": [], "t": []}], "preferred_name": "PROTEIN BEAN1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39231:SF1", "l": "HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25", "d": [], "t": []}], "preferred_name": "HISTONE DEACETYLASE COMPLEX SUBUNIT SAP25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22903", "l": "PLEKHH PROTEIN", "d": [], "t": []}], "preferred_name": "PLEKHH PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24082", "l": "NUCLEAR HORMONE RECEPTOR", "d": [], "t": []}], "preferred_name": "NUCLEAR HORMONE RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19846", "l": "WD40 REPEAT PROTEIN", "d": [], "t": []}], "preferred_name": "WD40 REPEAT PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46332:SF1", "l": "ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "ASPARTATE BETA-HYDROXYLASE DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45742:SF2", "l": "COMPLEMENT COMPONENT C7", "d": [], "t": []}], "preferred_name": "COMPLEMENT COMPONENT C7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19338:SF6", "l": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8 A", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8 A", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11803", "l": "2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA", "d": [], "t": []}], "preferred_name": "2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11771:SF5", "l": "POLYUNSATURATED FATTY ACID 5-LIPOXYGENASE", "d": [], "t": []}], "preferred_name": "POLYUNSATURATED FATTY ACID 5-LIPOXYGENASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12749", "l": "EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1", "d": [], "t": []}], "preferred_name": "EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12151:SF4", "l": "PROTEIN SCO1 HOMOLOG, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "PROTEIN SCO1 HOMOLOG, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44793", "l": "MATRIX REMODELING-ASSOCIATED PROTEIN 8", "d": [], "t": []}], "preferred_name": "MATRIX REMODELING-ASSOCIATED PROTEIN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11042:SF183", "l": "MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE", "d": [], "t": []}], "preferred_name": "MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12771:SF8", "l": "ENGULFMENT AND CELL MOTILITY PROTEIN 2", "d": [], "t": []}], "preferred_name": "ENGULFMENT AND CELL MOTILITY PROTEIN 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15012:SF35", "l": "PROTEIN SHROOM4", "d": [], "t": []}], "preferred_name": "PROTEIN SHROOM4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23187", "l": "FLJ44216 PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "FLJ44216 PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46002:SF1", "l": "CALCINEURIN B HOMOLOGOUS PROTEIN 1", "d": [], "t": []}], "preferred_name": "CALCINEURIN B HOMOLOGOUS PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11860:SF103", "l": "CMRF35-LIKE MOLECULE 7", "d": [], "t": []}], "preferred_name": "CMRF35-LIKE MOLECULE 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13634:SF0", "l": "RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG", "d": [], "t": []}], "preferred_name": "RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16230:SF4", "l": "BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 4", "d": [], "t": []}], "preferred_name": "BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13105:SF4", "l": "MYELOID LEUKEMIA FACTOR 2", "d": [], "t": []}], "preferred_name": "MYELOID LEUKEMIA FACTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12069:SF0", "l": "DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5", "d": [], "t": []}], "preferred_name": "DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15298:SF7", "l": "GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10283:SF62", "l": "NA(+)_DICARBOXYLATE COTRANSPORTER 3", "d": [], "t": []}], "preferred_name": "NA(+)_DICARBOXYLATE COTRANSPORTER 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1382", "l": "45S pre-ribosomal RNAs", "d": ["The sequences coding for ribosomal RNAs are present as rDNA repeating units, designated RNR1 through RNR5, in the p12 region of chromosomes 13, 14, 15, 21 and 22. A 45S rRNA which serves as the precursor for the 18S, 5.8S and 28S rRNA, is transcribed from each rDNA unit by RNA polymerase I. The number of rDNA repeating units varies between individuals and from chromosome to chromosome, although usually 30 to 40 repeats are found on each chromosome. [Note that the clusters are extremely difficult to sequence and are therefore not represented on the reference genome assembly. Each gene symbol below is representative of one 45S pre-ribosomal RNA repeat unit per repeat cluster]"], "t": []}], "preferred_name": "45S pre-ribosomal RNAs", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13491", "l": "ZCCHC10 PROTEIN", "d": [], "t": []}], "preferred_name": "ZCCHC10 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1325", "l": "Synapsins", "d": ["The synapsins are a family of proteins that have long been implicated in the regulation of neurotransmitter release at synapses. Specifically, they are thought to be involved in regulating the number of synaptic vesicles available for release via exocytosis at any one time. Synapsins are present in invertebrates and vertebrates and are somewhat homologous across evaluated vertebrates.  Current studies suggest the following hypothesis for the role of synapsin: synapsins bind synaptic vesicles to components of the cytoskeleton which prevents them from migrating to the presynaptic membrane and releasing neurotransmitter. During an action potential, synapsins are phosphorylated by PKA (cAMP dependent protein kinase), releasing the synaptic vesicles and allowing them to move to the membrane and release their neurotransmitter.  Gene knockout studies in mice (where the mouse is unable to produce synapsin) have had some surprising results. Mice lacking all three synapsins are prone to seizures, and experience learning defects. These results suggest that while synapsins are not essential for synaptic function, they do serve an important modulatory role. Conversely, studies using transgenic mice in which neuronal signaling is abolished in specific circuitries showed that synaptic activity regulates, but is not essential to maintain, the expression of these proteins."], "t": []}], "preferred_name": "Synapsins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46465", "l": "LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG", "d": [], "t": []}], "preferred_name": "LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22765:SF345", "l": "RING FINGER PROTEIN 215", "d": [], "t": []}], "preferred_name": "RING FINGER PROTEIN 215", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12751:SF6", "l": "PHOSPHATASE AND ACTIN REGULATOR 1", "d": [], "t": []}], "preferred_name": "PHOSPHATASE AND ACTIN REGULATOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12345", "l": "SYNTENIN RELATED", "d": [], "t": []}], "preferred_name": "SYNTENIN RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11937:SF168", "l": "BETA-ACTIN-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "BETA-ACTIN-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11690:SF18", "l": "AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA", "d": [], "t": []}], "preferred_name": "AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14952:SF12", "l": "ROPPORIN-1B", "d": [], "t": []}], "preferred_name": "ROPPORIN-1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24412:SF475", "l": "KELCH-LIKE PROTEIN 17", "d": [], "t": []}], "preferred_name": "KELCH-LIKE PROTEIN 17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14865", "l": "CST COMPLEX SUBUNIT CTC1", "d": [], "t": []}], "preferred_name": "CST COMPLEX SUBUNIT CTC1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24233:SF0", "l": "P2Y PURINOCEPTOR 12", "d": [], "t": []}], "preferred_name": "P2Y PURINOCEPTOR 12", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13723:SF169", "l": "ADAMTS-LIKE PROTEIN 3", "d": [], "t": []}], "preferred_name": "ADAMTS-LIKE PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1065", "l": "Insulin like growth factor binding proteins", "d": [], "t": []}], "preferred_name": "Insulin like growth factor binding proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23235:SF77", "l": "KRUEPPEL-LIKE FACTOR 7", "d": [], "t": []}], "preferred_name": "KRUEPPEL-LIKE FACTOR 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14095:SF3", "l": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43243:SF17", "l": "CATIONIC AMINO ACID TRANSPORTER-RELATED", "d": [], "t": []}], "preferred_name": "CATIONIC AMINO ACID TRANSPORTER-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23348:SF41", "l": "NEUROBLAST DIFFERENTIATION-ASSOCIATED PROTEIN AHNAK", "d": [], "t": []}], "preferred_name": "NEUROBLAST DIFFERENTIATION-ASSOCIATED PROTEIN AHNAK", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16294:SF5", "l": "DYSBINDIN", "d": [], "t": []}], "preferred_name": "DYSBINDIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36468", "l": "SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "SPERMATOGENESIS-ASSOCIATED PROTEIN 19, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28630:SF29", "l": "PROSTAMIDE_PROSTAGLANDIN F SYNTHASE", "d": [], "t": []}], "preferred_name": "PROSTAMIDE_PROSTAGLANDIN F SYNTHASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10240", "l": "ALPHA-S1-CASEIN", "d": [], "t": []}], "preferred_name": "ALPHA-S1-CASEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11771:SF184", "l": "HYDROPEROXIDE ISOMERASE ALOXE3", "d": [], "t": []}], "preferred_name": "HYDROPEROXIDE ISOMERASE ALOXE3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10890:SF27", "l": "CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED", "d": [], "t": []}], "preferred_name": "CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21646:SF15", "l": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 44", "d": [], "t": []}], "preferred_name": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 44", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37355", "l": "PLACENTA-SPECIFIC PROTEIN 9", "d": [], "t": []}], "preferred_name": "PLACENTA-SPECIFIC PROTEIN 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11782:SF31", "l": "ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 8", "d": [], "t": []}], "preferred_name": "ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10984:SF36", "l": "ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1", "d": [], "t": []}], "preferred_name": "ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47671", "l": "PLECKSTRIN DOMAIN-CONTAINING FAMILY G MEMBER 6", "d": [], "t": []}], "preferred_name": "PLECKSTRIN DOMAIN-CONTAINING FAMILY G MEMBER 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11571:SF257", "l": "GLUTATHIONE S-TRANSFERASE A3", "d": [], "t": []}], "preferred_name": "GLUTATHIONE S-TRANSFERASE A3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15708:SF8", "l": "PROTEIN MTSS 2", "d": [], "t": []}], "preferred_name": "PROTEIN MTSS 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23426:SF26", "l": "ADRENODOXIN, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ADRENODOXIN, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31291", "l": "ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO", "d": [], "t": []}], "preferred_name": "ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE FTO", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48207:SF3", "l": "SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE", "d": [], "t": []}], "preferred_name": "SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46320:SF1", "l": "GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1", "d": [], "t": []}], "preferred_name": "GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44656:SF7", "l": "DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12", "d": [], "t": []}], "preferred_name": "DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24064:SF217", "l": "SOLUTE CARRIER FAMILY 22 MEMBER 25", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 22 MEMBER 25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13048:SF2", "l": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3", "d": [], "t": []}], "preferred_name": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26450", "l": "OLFACTORY RECEPTOR 56B1-RELATED", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 56B1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13809:SF1", "l": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-11", "d": [], "t": []}], "preferred_name": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28511", "l": "ENDONUCLEASE V", "d": [], "t": []}], "preferred_name": "ENDONUCLEASE V", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46858", "l": "OS05G0521000 PROTEIN", "d": [], "t": []}], "preferred_name": "OS05G0521000 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22804:SF11", "l": "HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 4", "d": [], "t": []}], "preferred_name": "HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11941:SF27", "l": "ETHYLMALONYL-COA DECARBOXYLASE", "d": [], "t": []}], "preferred_name": "ETHYLMALONYL-COA DECARBOXYLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11849:SF31", "l": "ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF", "d": [], "t": []}], "preferred_name": "ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15420", "l": "UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN", "d": [], "t": []}], "preferred_name": "UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14136", "l": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9", "d": [], "t": []}], "preferred_name": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10300", "l": "CALCIPRESSIN", "d": [], "t": []}], "preferred_name": "CALCIPRESSIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21243:SF15", "l": "PROTEIN SCAI", "d": [], "t": []}], "preferred_name": "PROTEIN SCAI", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15566:SF6", "l": "POM121-LIKE PROTEIN 1-RELATED", "d": [], "t": []}], "preferred_name": "POM121-LIKE PROTEIN 1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37343:SF1", "l": "PROLINE-RICH PROTEIN 32", "d": [], "t": []}], "preferred_name": "PROLINE-RICH PROTEIN 32", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22829", "l": "DEP DOMAIN PROTEIN", "d": [], "t": []}], "preferred_name": "DEP DOMAIN PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12101", "l": "POPEYE DOMAIN CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "POPEYE DOMAIN CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24339:SF29", "l": "GS HOMEOBOX 1", "d": [], "t": []}], "preferred_name": "GS HOMEOBOX 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15710:SF21", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF126", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF126", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11092", "l": "SUGAR NUCLEOTIDE EPIMERASE RELATED", "d": [], "t": []}], "preferred_name": "SUGAR NUCLEOTIDE EPIMERASE RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:483", "l": "Chemokine ligands", "d": ["Chemokines (Greek -kinos, movement) are a family of small cytokines, or signaling proteins secreted by cells. Their name is derived from their ability to induce directed chemotaxis in nearby responsive cells; they are chemo tactic cyto kines. Proteins are classified as chemokines according to shared structural characteristics such as small size (they are all approximately 8-10 kilodaltons in size), and the presence of four cysteine residues in conserved locations that are key to forming their 3-dimensional shape. However, these proteins have historically been known under several other names including the SIS family of cytokines, SIG family of cytokines, SCY family of cytokines, Platelet factor-4 superfamily or intercrines. Some chemokines are considered pro- inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria, but none have been described for other invertebrates.  Chemokines have been classified into four main subfamilies : CXC, CC, CX3C and XC. All of these proteins exert their biological effects by interacting with G protein -linked transmembrane receptors called chemokine receptors, that are selectively found on the surfaces of their target cells."], "t": []}], "preferred_name": "Chemokine ligands", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10159:SF388", "l": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 9", "d": [], "t": []}], "preferred_name": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24383:SF13", "l": "FLT3-INTERACTING ZINC FINGER PROTEIN 1", "d": [], "t": []}], "preferred_name": "FLT3-INTERACTING ZINC FINGER PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23266:SF389", "l": "IMMUNOGLOBULIN HEAVY VARIABLE 2-70-RELATED", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN HEAVY VARIABLE 2-70-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37864:SF1", "l": "SIMILAR TO AVLV472", "d": [], "t": []}], "preferred_name": "SIMILAR TO AVLV472", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2215", "l": "Solute carrier family 66", "d": [], "t": []}], "preferred_name": "Solute carrier family 66", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF359", "l": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-22", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN LAMBDA VARIABLE 3-22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11071:SF408", "l": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11538", "l": "PHENYLALANYL-TRNA SYNTHETASE", "d": [], "t": []}], "preferred_name": "PHENYLALANYL-TRNA SYNTHETASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10516:SF301", "l": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED", "d": [], "t": []}], "preferred_name": "PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:624", "l": "KLF transcription factors", "d": ["The Kruppel-like family of transcription factors (KLFs) are a set of zinc finger DNA-binding proteins that regulate gene expression."], "t": []}], "preferred_name": "KLF transcription factors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12804:SF0", "l": "SIGNAL PEPTIDASE COMPLEX SUBUNIT 3", "d": [], "t": []}], "preferred_name": "SIGNAL PEPTIDASE COMPLEX SUBUNIT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23107", "l": "SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN", "d": [], "t": []}], "preferred_name": "SYNOVIAL SARCOMA ASSOCIATED SS18 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11822:SF28", "l": "ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC", "d": [], "t": []}], "preferred_name": "ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36982", "l": "CLCA DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "CLCA DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24304:SF1", "l": "CYTOCHROME P450 7A1", "d": [], "t": []}], "preferred_name": "CYTOCHROME P450 7A1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10270:SF113", "l": "TRANSCRIPTION FACTOR SOX-11", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR SOX-11", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11759:SF3", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN US11M", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN US11M", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15002:SF0", "l": "RIBOSOMAL BIOGENESIS PROTEIN LAS1L", "d": [], "t": []}], "preferred_name": "RIBOSOMAL BIOGENESIS PROTEIN LAS1L", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15417:SF5", "l": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3648", "l": "Microprocessor complex", "d": [], "t": []}], "preferred_name": "Microprocessor complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2154", "l": "Solute carrier family 1", "d": [], "t": []}], "preferred_name": "Solute carrier family 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44029:SF1", "l": "DNAJ HOMOLOG SUBFAMILY C MEMBER 21", "d": [], "t": []}], "preferred_name": "DNAJ HOMOLOG SUBFAMILY C MEMBER 21", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1040", "l": "Ragulator complex", "d": [], "t": []}], "preferred_name": "Ragulator complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45679:SF6", "l": "ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14058", "l": "AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B", "d": [], "t": []}], "preferred_name": "AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32035", "l": "AURORA KINASE A-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "AURORA KINASE A-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13886:SF3", "l": "C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3", "d": [], "t": []}], "preferred_name": "C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23320:SF130", "l": "TRANSMEMBRANE PROTEIN 212", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 212", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24214:SF7", "l": "PDZ AND LIM DOMAIN PROTEIN 3", "d": [], "t": []}], "preferred_name": "PDZ AND LIM DOMAIN PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16046:SF11", "l": "PROTEIN FAM178B", "d": [], "t": []}], "preferred_name": "PROTEIN FAM178B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13091:SF0", "l": "NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8", "d": [], "t": []}], "preferred_name": "NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10378:SF7", "l": "LIM DOMAIN-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "LIM DOMAIN-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12113:SF10", "l": "DICKKOPF-RELATED PROTEIN 4", "d": [], "t": []}], "preferred_name": "DICKKOPF-RELATED PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11010:SF38", "l": "LYSOSOMAL PRO-X CARBOXYPEPTIDASE", "d": [], "t": []}], "preferred_name": "LYSOSOMAL PRO-X CARBOXYPEPTIDASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:553", "l": "Fatty acid desaturases", "d": ["A fatty acid desaturase is an enzyme that removes two hydrogen atoms from a fatty acid, creating a carbon /carbon double bond."], "t": []}], "preferred_name": "Fatty acid desaturases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44427:SF25", "l": "CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 7", "d": [], "t": []}], "preferred_name": "CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47969", "l": "CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED", "d": [], "t": []}], "preferred_name": "CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11388:SF142", "l": "SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11972:SF60", "l": "CYTOCHROME B-245 HEAVY CHAIN", "d": [], "t": []}], "preferred_name": "CYTOCHROME B-245 HEAVY CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47500:SF2", "l": "EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21017:SF23", "l": "PROTEIN NIPSNAP HOMOLOG 3A", "d": [], "t": []}], "preferred_name": "PROTEIN NIPSNAP HOMOLOG 3A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF166", "l": "SERPIN B8", "d": [], "t": []}], "preferred_name": "SERPIN B8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16140:SF2", "l": "NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 HOMOLOG A", "d": [], "t": []}], "preferred_name": "NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 HOMOLOG A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11211:SF13", "l": "IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1", "d": [], "t": []}], "preferred_name": "IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43084", "l": "PERSULFIDE DIOXYGENASE ETHE1", "d": [], "t": []}], "preferred_name": "PERSULFIDE DIOXYGENASE ETHE1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10286:SF49", "l": "INORGANIC PYROPHOSPHATASE 2, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "INORGANIC PYROPHOSPHATASE 2, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23268:SF91", "l": "T CELL RECEPTOR BETA VARIABLE 12-5", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA VARIABLE 12-5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24088:SF2", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN US17M", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN US17M", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19818:SF167", "l": "ZINC FINGER PROTEIN ZIC 4", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN ZIC 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11241:SF11", "l": "DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14978:SF4", "l": "BETA-CATENIN-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "BETA-CATENIN-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10663:SF388", "l": "GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1", "d": [], "t": []}], "preferred_name": "GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12630:SF6", "l": "N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA", "d": [], "t": []}], "preferred_name": "N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37873:SF1", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 33", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 33", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2258", "l": "Flavoproteins", "d": ["Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin. These proteins are involved in a wide array of biological processes, including removal of radicals contributing to oxidative stress, photosynthesis, and DNA repair. The flavoproteins are some of the most-studied families of enzymes.  Flavoproteins have either FMN (flavin mononucleotide) or FAD (flavin adenine dinucleotide) as a prosthetic group or as a cofactor. The flavin is generally tightly bound (as in adrenodoxin reductase, wherein the FAD is buried deeply). About 5-10% of flavoproteins have a covalently linked FAD. Based on the available structural data, FAD-binding sites can be divided into more than 200 different types.90 flavoproteins are encoded in the human genome; about 84% require FAD and around 16% require FMN, whereas 5 proteins require both. Flavoproteins are mainly located in the mitochondria. Of all flavoproteins, 90% perform redox reactions and the other 10% are transferases, lyases, isomerases, ligases."], "t": []}], "preferred_name": "Flavoproteins", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10159:SF109", "l": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 2", "d": [], "t": []}], "preferred_name": "DUAL SPECIFICITY PROTEIN PHOSPHATASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:822", "l": "Synaptotagmin like tandem C2 proteins", "d": ["This family contains proteins with tandem C-terminal cytoplasmic C2 domains that are similar to those found in synaptotagmins, but the N-terminal parts of the proteins differ from the synaptotagmin family."], "t": []}], "preferred_name": "Synaptotagmin like tandem C2 proteins", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23352:SF2", "l": "NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1", "d": [], "t": []}], "preferred_name": "NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45975:SF2", "l": "NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF", "d": [], "t": []}], "preferred_name": "NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23359", "l": "NUCLEOTIDE KINASE", "d": [], "t": []}], "preferred_name": "NUCLEOTIDE KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1742", "l": "MicroRNA MIR33 family", "d": ["miR-33 is a family of microRNA precursors, which are processed by the Dicer enzyme to give mature microRNAs. miR-33 is found in several animal species, including humans. In some species there is a single member of this family which gives the mature product mir-33. In humans there are two members of this family called mir-33a and mir-33b, which are located in intronic regions within two protein-coding genes for Sterol regulatory element-binding proteins (SREBP-2 and SREBP-1) respectively."], "t": []}], "preferred_name": "MicroRNA MIR33 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45691:SF3", "l": "PROTEIN DIAPHANOUS HOMOLOG 2", "d": [], "t": []}], "preferred_name": "PROTEIN DIAPHANOUS HOMOLOG 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31921:SF1", "l": "PROTEIN DPCD", "d": [], "t": []}], "preferred_name": "PROTEIN DPCD", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24031:SF292", "l": "ATP-DEPENDENT RNA HELICASE DDX54", "d": [], "t": []}], "preferred_name": "ATP-DEPENDENT RNA HELICASE DDX54", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24023:SF1071", "l": "COLLAGEN ALPHA-1(VII) CHAIN", "d": [], "t": []}], "preferred_name": "COLLAGEN ALPHA-1(VII) CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2070", "l": "Thyroid hormone receptors", "d": [], "t": []}], "preferred_name": "Thyroid hormone receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11254:SF66", "l": "E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE ITCHY HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13067:SF2", "l": "CASPASE-ACTIVATED DNASE", "d": [], "t": []}], "preferred_name": "CASPASE-ACTIVATED DNASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32546:SF7", "l": "G-PROTEIN COUPLED RECEPTOR 179-RELATED", "d": [], "t": []}], "preferred_name": "G-PROTEIN COUPLED RECEPTOR 179-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12497", "l": "TAZ PROTEIN  TAFAZZIN", "d": [], "t": []}], "preferred_name": "TAZ PROTEIN  TAFAZZIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13316", "l": "ZINC FINGER, CCHC DOMAIN CONTAINING 8", "d": [], "t": []}], "preferred_name": "ZINC FINGER, CCHC DOMAIN CONTAINING 8", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15083:SF0", "l": "NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6", "d": [], "t": []}], "preferred_name": "NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10309:SF0", "l": "MANNOSE-6-PHOSPHATE ISOMERASE", "d": [], "t": []}], "preferred_name": "MANNOSE-6-PHOSPHATE ISOMERASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23089", "l": "HISTIDINE TRIAD  HIT  PROTEIN", "d": [], "t": []}], "preferred_name": "HISTIDINE TRIAD  HIT  PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:218", "l": "Chemerin receptors", "d": [], "t": []}], "preferred_name": "Chemerin receptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46712", "l": "PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13465:SF2", "l": "PHAGOSOME ASSEMBLY FACTOR 1", "d": [], "t": []}], "preferred_name": "PHAGOSOME ASSEMBLY FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22624:SF35", "l": "CYSTEINE PROTEASE ATG4A", "d": [], "t": []}], "preferred_name": "CYSTEINE PROTEASE ATG4A", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14964", "l": "NUCLEAR RECEPTOR BINDING FACTOR 2", "d": [], "t": []}], "preferred_name": "NUCLEAR RECEPTOR BINDING FACTOR 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14369:SF0", "l": "SURFEIT LOCUS PROTEIN 6", "d": [], "t": []}], "preferred_name": "SURFEIT LOCUS PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14392:SF3", "l": "PROTEIN NIBAN 1", "d": [], "t": []}], "preferred_name": "PROTEIN NIBAN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17045:SF7", "l": "CBP_P300-INTERACTING TRANSACTIVATOR 2", "d": [], "t": []}], "preferred_name": "CBP_P300-INTERACTING TRANSACTIVATOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3660", "l": "Tubulin alpha family", "d": ["Alpha-tubulins are globular GTP-binding proteins that, together with beta-tubulins, form the alpha/beta-tubulin heterodimer, the fundamental building block of microtubules in eukaryotic cells. Unlike beta-tubulin, alpha-tubulin binds GTP non-exchangeably."], "t": []}], "preferred_name": "Tubulin alpha family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23344:SF13", "l": "GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 4", "d": [], "t": []}], "preferred_name": "GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15407:SF28", "l": "RIBITOL-5-PHOSPHATE TRANSFERASE FKTN", "d": [], "t": []}], "preferred_name": "RIBITOL-5-PHOSPHATE TRANSFERASE FKTN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47385:SF20", "l": "TRANSGELIN-2", "d": [], "t": []}], "preferred_name": "TRANSGELIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24171:SF8", "l": "BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1", "d": [], "t": []}], "preferred_name": "BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15506:SF2", "l": "MAJOR PRION PROTEIN", "d": [], "t": []}], "preferred_name": "MAJOR PRION PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24027:SF78", "l": "CADHERIN-LIKE PROTEIN 26", "d": [], "t": []}], "preferred_name": "CADHERIN-LIKE PROTEIN 26", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16112:SF18", "l": "METHYL-CPG-BINDING DOMAIN PROTEIN 5", "d": [], "t": []}], "preferred_name": "METHYL-CPG-BINDING DOMAIN PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13186:SF0", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12299", "l": "HYALURONIC ACID-BINDING PROTEIN 4", "d": [], "t": []}], "preferred_name": "HYALURONIC ACID-BINDING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10792:SF44", "l": "LARGE RIBOSOMAL SUBUNIT PROTEIN EL24", "d": [], "t": []}], "preferred_name": "LARGE RIBOSOMAL SUBUNIT PROTEIN EL24", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15813", "l": "SORTING NEXIN-22 AND 24", "d": [], "t": []}], "preferred_name": "SORTING NEXIN-22 AND 24", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23065", "l": "PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1", "d": [], "t": []}], "preferred_name": "PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31774:SF14", "l": "PROTEIN SHISA-8", "d": [], "t": []}], "preferred_name": "PROTEIN SHISA-8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11787:SF12", "l": "RAB PROTEINS GERANYLGERANYLTRANSFERASE COMPONENT A 1", "d": [], "t": []}], "preferred_name": "RAB PROTEINS GERANYLGERANYLTRANSFERASE COMPONENT A 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23167:SF3", "l": "CYTOSPIN-B", "d": [], "t": []}], "preferred_name": "CYTOSPIN-B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34256", "l": "UPF0561 PROTEIN C2ORF68", "d": [], "t": []}], "preferred_name": "UPF0561 PROTEIN C2ORF68", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3792", "l": "Ataxin 1 family", "d": ["ATXN1 (ataxin 1) and ATXN1L (ataxin 1 like) are paralogous genes encoding nuclear proteins that function primarily as transcriptional regulators within multiprotein chromatin complexes. Their molecular functions are best understood through shared interaction partners (especially CIC) and genetic studies showing partial redundancy. Expansions of a polyglutamine tract in ATXN1 are associated with Spinocerebellar ataxia 1."], "t": []}], "preferred_name": "Ataxin 1 family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14025:SF20", "l": "FANCONI ANEMIA GROUP M PROTEIN", "d": [], "t": []}], "preferred_name": "FANCONI ANEMIA GROUP M PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46822", "l": "COILED-COIL ALPHA-HELICAL ROD PROTEIN 1", "d": [], "t": []}], "preferred_name": "COILED-COIL ALPHA-HELICAL ROD PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3740", "l": "Translocon associated protein complex subunits", "d": ["The TRAP complex regulates glycosylation for a subset of ER-translated proteins under conditions of ER stress."], "t": []}], "preferred_name": "Translocon associated protein complex subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42884:SF16", "l": "PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 4", "d": [], "t": []}], "preferred_name": "PROPROTEIN CONVERTASE SUBTILISIN_KEXIN TYPE 4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12651:SF1", "l": "26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9", "d": [], "t": []}], "preferred_name": "26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26452:SF315", "l": "OLFACTORY RECEPTOR 5AR1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 5AR1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24314:SF20", "l": "STEROL CARRIER PROTEIN 2", "d": [], "t": []}], "preferred_name": "STEROL CARRIER PROTEIN 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31302:SF0", "l": "TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN WITH METALLOPHOSPHOESTERASE DOMAIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32094", "l": "FANCONI ANEMIA GROUP E PROTEIN", "d": [], "t": []}], "preferred_name": "FANCONI ANEMIA GROUP E PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42985:SF2", "l": "SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER", "d": [], "t": []}], "preferred_name": "SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44791", "l": "TELOMERASE PROTEIN COMPONENT 1 TEP1", "d": [], "t": []}], "preferred_name": "TELOMERASE PROTEIN COMPONENT 1 TEP1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2217", "l": "Dispatched RND transporter family", "d": [], "t": []}], "preferred_name": "Dispatched RND transporter family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45822:SF5", "l": "FREE FATTY ACID RECEPTOR 2", "d": [], "t": []}], "preferred_name": "FREE FATTY ACID RECEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11589", "l": "NERVE GROWTH FACTOR  NGF -RELATED", "d": [], "t": []}], "preferred_name": "NERVE GROWTH FACTOR  NGF -RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:452", "l": "Biogenesis of lysosomal organelles complex 1 subunits", "d": ["BLOC-1 or biogenesis of lysosome-related organelles complex 1 is a ubiquitously expressed multisubunit protein complex. BLOC-1 is required for normal biogenesis of specialized organelles of the endosomal -lysosomal system, such as melanosomes and platelet dense granules."], "t": []}], "preferred_name": "Biogenesis of lysosomal organelles complex 1 subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31078", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 300", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24264:SF46", "l": "COAGULATION FACTOR XII", "d": [], "t": []}], "preferred_name": "COAGULATION FACTOR XII", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23127", "l": "CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5", "d": [], "t": []}], "preferred_name": "CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11935", "l": "BETA LACTAMASE DOMAIN", "d": [], "t": []}], "preferred_name": "BETA LACTAMASE DOMAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11570", "l": "S-ADENOSYLMETHIONINE DECARBOXYLASE", "d": [], "t": []}], "preferred_name": "S-ADENOSYLMETHIONINE DECARBOXYLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15995:SF1", "l": "PROTEIN ZWILCH HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN ZWILCH HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21545:SF10", "l": "LIGAND-DEPENDENT NUCLEAR RECEPTOR COREPRESSOR-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "LIGAND-DEPENDENT NUCLEAR RECEPTOR COREPRESSOR-LIKE PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24025:SF0", "l": "DESMOCOLLIN-2", "d": [], "t": []}], "preferred_name": "DESMOCOLLIN-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23095:SF20", "l": "PARANEOPLASTIC ANTIGEN MA6E", "d": [], "t": []}], "preferred_name": "PARANEOPLASTIC ANTIGEN MA6E", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23093", "l": "SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20", "d": [], "t": []}], "preferred_name": "SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23430:SF42", "l": "HISTONE H2A TYPE 2-A", "d": [], "t": []}], "preferred_name": "HISTONE H2A TYPE 2-A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1407", "l": "Myocardin family", "d": [], "t": []}], "preferred_name": "Myocardin family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21683:SF8", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 42", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 42", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11036:SF16", "l": "SEMAPHORIN-4C", "d": [], "t": []}], "preferred_name": "SEMAPHORIN-4C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24379:SF75", "l": "VASCULAR ENDOTHELIAL ZINC FINGER 1", "d": [], "t": []}], "preferred_name": "VASCULAR ENDOTHELIAL ZINC FINGER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10266:SF3", "l": "CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3679", "l": "ZNF804 family", "d": ["These three paralogs all have a C2H2 zinc finger and a small beta-sheet domain but only GPATCH8 has a GPATCH domain."], "t": []}], "preferred_name": "ZNF804 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21389", "l": "P53 INDUCED PROTEIN", "d": [], "t": []}], "preferred_name": "P53 INDUCED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14200", "l": "CYTOCHROME C OXIDASE POLYPEPTIDE", "d": [], "t": []}], "preferred_name": "CYTOCHROME C OXIDASE POLYPEPTIDE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11055:SF17", "l": "BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10339", "l": "ADP-RIBOSYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "ADP-RIBOSYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24384:SF181", "l": "ZINC FINGER PROTEIN 253", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 253", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15082", "l": "NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13011", "l": "TFIIF-ALPHA", "d": [], "t": []}], "preferred_name": "TFIIF-ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43856", "l": "CARDIOLIPIN HYDROLASE", "d": [], "t": []}], "preferred_name": "CARDIOLIPIN HYDROLASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:637", "l": "MAX dimerization proteins", "d": [], "t": []}], "preferred_name": "MAX dimerization proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12307", "l": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10706:SF130", "l": "F-BOX ONLY PROTEIN 31", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 31", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3938", "l": "STE-unique family", "d": [], "t": []}], "preferred_name": "STE-unique family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14758:SF4", "l": "PROTEIN FAM110A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM110A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35973", "l": "MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE", "d": [], "t": []}], "preferred_name": "MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3793", "l": "Ataxin 2 family", "d": ["ATXN2 and ATXN2L are paralogs that encode proteins contain Lsm and LsmAD domains for binding to RNA, and a PAM2 motif for interaction with PABP. Expansions of a polygluatamine tract in ATXN2 cause spinocerebellar ataxia 2 (SCA2). The polygluatamine tract is not found in ATXN2L.  ATXN2 protein is involved in mRNA degradation, stability, and translation by modulating the PABP protein, 3′ untranslated regions, and stress granule and P-body formation. ATXN2L is involved in stress granule and RNA metabolism."], "t": []}], "preferred_name": "Ataxin 2 family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12598:SF0", "l": "COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG", "d": [], "t": []}], "preferred_name": "COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF278", "l": "IMMUNOGLOBULIN KAPPA VARIABLE 2-30-RELATED", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN KAPPA VARIABLE 2-30-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23086:SF21", "l": "PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE TYPE-2 ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18962:SF0", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 39", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 39", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1841", "l": "LGI family", "d": [], "t": []}], "preferred_name": "LGI family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16877", "l": "HEPCIDIN", "d": [], "t": []}], "preferred_name": "HEPCIDIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13388:SF9", "l": "TRANSMEMBRANE PROTEIN 132A", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 132A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46511", "l": "MORN REPEAT-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "MORN REPEAT-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22937", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF165", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF165", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22574:SF5", "l": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5A", "d": [], "t": []}], "preferred_name": "GOLGI-ASSOCIATED RAB2 INTERACTOR PROTEIN 5A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3671", "l": "UBR4 complex", "d": [], "t": []}], "preferred_name": "UBR4 complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22118:SF14", "l": "DYNEIN AXONEMAL ASSEMBLY FACTOR 3", "d": [], "t": []}], "preferred_name": "DYNEIN AXONEMAL ASSEMBLY FACTOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15363", "l": "POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1", "d": [], "t": []}], "preferred_name": "POU DOMAIN CLASS 2-ASSOCIATING FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10383:SF16", "l": "SERINE INCORPORATOR 5", "d": [], "t": []}], "preferred_name": "SERINE INCORPORATOR 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10559", "l": "TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR", "d": [], "t": []}], "preferred_name": "TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21686:SF12", "l": "DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2", "d": [], "t": []}], "preferred_name": "DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13131", "l": "CYSTINOSIN", "d": [], "t": []}], "preferred_name": "CYSTINOSIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12300", "l": "HVA22-LIKE PROTEINS", "d": [], "t": []}], "preferred_name": "HVA22-LIKE PROTEINS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23086", "l": "PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12411:SF16", "l": "CATHEPSIN B", "d": [], "t": []}], "preferred_name": "CATHEPSIN B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3676", "l": "Receptor interacting serine/threonine kinase family", "d": [], "t": []}], "preferred_name": "Receptor interacting serine/threonine kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12387:SF1", "l": "26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8", "d": [], "t": []}], "preferred_name": "26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14499:SF20", "l": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD19", "d": [], "t": []}], "preferred_name": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46874:SF1", "l": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6", "d": [], "t": []}], "preferred_name": "TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45897", "l": "HIGH-AFFINITY CHOLINE TRANSPORTER 1", "d": [], "t": []}], "preferred_name": "HIGH-AFFINITY CHOLINE TRANSPORTER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14402:SF18", "l": "RECEPTOR-TRANSPORTING PROTEIN 2", "d": [], "t": []}], "preferred_name": "RECEPTOR-TRANSPORTING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47056:SF1", "l": "RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39", "d": [], "t": []}], "preferred_name": "RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 39", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13720:SF40", "l": "WD REPEAT-CONTAINING PROTEIN 54", "d": [], "t": []}], "preferred_name": "WD REPEAT-CONTAINING PROTEIN 54", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22684:SF0", "l": "RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25", "d": [], "t": []}], "preferred_name": "RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11716:SF5", "l": "INACTIVE GROUP IIC SECRETORY PHOSPHOLIPASE A2-RELATED", "d": [], "t": []}], "preferred_name": "INACTIVE GROUP IIC SECRETORY PHOSPHOLIPASE A2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15045", "l": "FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42152:SF1", "l": "PROTEIN GDF5-AS1, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "PROTEIN GDF5-AS1, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45726", "l": "LEUKOTRIENE A-4 HYDROLASE", "d": [], "t": []}], "preferred_name": "LEUKOTRIENE A-4 HYDROLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31186", "l": "MODULATOR OF SMOOTHENED PROTEIN", "d": [], "t": []}], "preferred_name": "MODULATOR OF SMOOTHENED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24093:SF377", "l": "PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2", "d": [], "t": []}], "preferred_name": "PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF277", "l": "ZINC FINGER PROTEIN 461", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 461", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11157:SF68", "l": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 3", "d": [], "t": []}], "preferred_name": "ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24253", "l": "TRANSMEMBRANE PROTEASE SERINE", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEASE SERINE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15341:SF3", "l": "NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D", "d": [], "t": []}], "preferred_name": "NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22961:SF17", "l": "TRIBBLES HOMOLOG 1", "d": [], "t": []}], "preferred_name": "TRIBBLES HOMOLOG 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11670:SF32", "l": "CYTOPLASMIC ACONITATE HYDRATASE", "d": [], "t": []}], "preferred_name": "CYTOPLASMIC ACONITATE HYDRATASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33895:SF3", "l": "HUMANIN-LIKE 10", "d": [], "t": []}], "preferred_name": "HUMANIN-LIKE 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17616", "l": "YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10075:SF63", "l": "CONTACTIN-4", "d": [], "t": []}], "preferred_name": "CONTACTIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10962:SF4", "l": "INTEGRAL MEMBRANE PROTEIN 2B", "d": [], "t": []}], "preferred_name": "INTEGRAL MEMBRANE PROTEIN 2B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36864:SF1", "l": "CANCER-ASSOCIATED GENE 1 PROTEIN", "d": [], "t": []}], "preferred_name": "CANCER-ASSOCIATED GENE 1 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16056:SF18", "l": "REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 3", "d": [], "t": []}], "preferred_name": "REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48001:SF107", "l": "OLFACTORY RECEPTOR 7D2", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 7D2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1514", "l": "Calcium voltage-gated channel auxiliary alpha2delta subunits", "d": ["Voltage-dependent calcium channels ( VDCCs ) are a group of voltage-gated ion channels found in the membrane of excitable cells ( e.g., muscle, glial cells, neurons, etc.) with a permeability to the calcium ion Ca 2+. These channels are slightly permeable to sodium ions, so they are also called Ca 2+ -Na + channels, but their permeability to calcium is about 1000-fold greater than to sodium under normal physiological conditions. At physiologic or resting membrane potential, VDCCs are normally closed. They are activated ( i.e., opened) at depolarized membrane potentials and this is the source of the 'voltage-dependent' epithet. The concentration of calcium (Ca 2+ ions) is normally several thousand times higher outside of the cell than inside. Activation of particular VDCCs allows Ca 2+ to rush into the cell, which, depending on the cell type, results in activation of calcium-sensitive potassium channels, muscular contraction, excitation of neurons, up-regulation of gene expression, or release of hormones or neurotransmitters. VDCCs have been immunolocalized in the zona glomerulosa of normal and hyperplastic human adrenal, as well as in aldosterone -producing adenomas (APA), and in the latter T-type VDCCs correlated with plasma aldosterone levels of patients. Excessive activation of VDCCs is a major component of excitotoxicity, as severely elevated levels of intracellular calcium activates enzymes which, at high enough levels, can degrade essential cellular structures."], "t": []}], "preferred_name": "Calcium voltage-gated channel auxiliary alpha2delta subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10741", "l": "TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X", "d": [], "t": []}], "preferred_name": "TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26452", "l": "OLFACTORY RECEPTOR", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12329:SF12", "l": "BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3", "d": [], "t": []}], "preferred_name": "BAG FAMILY MOLECULAR CHAPERONE REGULATOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1750", "l": "General transcription factor IIF complex subunits", "d": ["Transcription factor IIF (TFIIF) is one of several general transcription factors that make up the RNA polymerase II preinitiation complex.Transcription factor IIF is encoded by the GTF2F1, GTF2F2, and GTF2F2L genes.TFIIF binds to RNA Polymerase II when the enzyme is already unbound to any other transcription factor, thus avoiding it from contacting DNA outside the promoter. Furthermore, TFIIF stabilizes the RNA polymerase II while it's contacting TBP and TFIIB."], "t": []}], "preferred_name": "General transcription factor IIF complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF102", "l": "OLFACTORY RECEPTOR 2L13", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 2L13", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12015:SF110", "l": "C-C MOTIF CHEMOKINE 14", "d": [], "t": []}], "preferred_name": "C-C MOTIF CHEMOKINE 14", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11352", "l": "PROLIFERATING CELL NUCLEAR ANTIGEN", "d": [], "t": []}], "preferred_name": "PROLIFERATING CELL NUCLEAR ANTIGEN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12834", "l": "SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN", "d": [], "t": []}], "preferred_name": "SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26450:SF58", "l": "OLFACTORY RECEPTOR 52W1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 52W1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24093", "l": "CATION TRANSPORTING ATPASE", "d": [], "t": []}], "preferred_name": "CATION TRANSPORTING ATPASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2101", "l": "Cleavage factor Im complex subunits", "d": [], "t": []}], "preferred_name": "Cleavage factor Im complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13486", "l": "TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17600", "l": "MESODERM DEVELOPMENT CANDIDATE 2", "d": [], "t": []}], "preferred_name": "MESODERM DEVELOPMENT CANDIDATE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24092:SF78", "l": "PHOSPHOLIPID-TRANSPORTING ATPASE IK", "d": [], "t": []}], "preferred_name": "PHOSPHOLIPID-TRANSPORTING ATPASE IK", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45700:SF3", "l": "UBIQUITIN-PROTEIN LIGASE E3B", "d": [], "t": []}], "preferred_name": "UBIQUITIN-PROTEIN LIGASE E3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37875:SF1", "l": "CHROMOSOME 3 OPEN READING FRAME 22", "d": [], "t": []}], "preferred_name": "CHROMOSOME 3 OPEN READING FRAME 22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23037:SF27", "l": "INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-7 RECEPTOR SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13274", "l": "MITOCHONDRIAL RIBOSOMAL PROTEIN S25", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL RIBOSOMAL PROTEIN S25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13809:SF19", "l": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-8", "d": [], "t": []}], "preferred_name": "GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(O) SUBUNIT GAMMA-8", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14407", "l": "HERMANSKY-PUDLAK SYNDROME 4 PROTEIN  LIGHT-EAR PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "HERMANSKY-PUDLAK SYNDROME 4 PROTEIN  LIGHT-EAR PROTEIN-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1044", "l": "EYA transcriptional coactivator and phosphatases", "d": [], "t": []}], "preferred_name": "EYA transcriptional coactivator and phosphatases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24240:SF15", "l": "RHODOPSIN", "d": [], "t": []}], "preferred_name": "RHODOPSIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13604", "l": "DC12-RELATED", "d": [], "t": []}], "preferred_name": "DC12-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10151:SF79", "l": "BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4", "d": [], "t": []}], "preferred_name": "BIS(5'-ADENOSYL)-TRIPHOSPHATASE ENPP4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3390", "l": "Zinc fingers UBZ3 CCHH-type", "d": ["The UBZ domain adopts a classical C2H2 zinc-finger structure characterized by a β-β-α fold; there are 4 different types of UBZ zinc finger with this group representing the CCHH-type zinc finger found in polymerase eta."], "t": []}], "preferred_name": "Zinc fingers UBZ3 CCHH-type", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46485:SF3", "l": "DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 1", "d": [], "t": []}], "preferred_name": "DUAL SPECIFICITY TESTIS-SPECIFIC PROTEIN KINASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47765:SF2", "l": "EXONUCLEASE MUT-7 HOMOLOG", "d": [], "t": []}], "preferred_name": "EXONUCLEASE MUT-7 HOMOLOG", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22762:SF162", "l": "NEUTRAL ALPHA-GLUCOSIDASE AB", "d": [], "t": []}], "preferred_name": "NEUTRAL ALPHA-GLUCOSIDASE AB", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14633", "l": "LITTLE ELONGATION COMPLEX SUBUNIT 2", "d": [], "t": []}], "preferred_name": "LITTLE ELONGATION COMPLEX SUBUNIT 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15720:SF13", "l": "PROTEIN GREB1", "d": [], "t": []}], "preferred_name": "PROTEIN GREB1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46531:SF1", "l": "ZINC TRANSPORTER 6", "d": [], "t": []}], "preferred_name": "ZINC TRANSPORTER 6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13948:SF21", "l": "RNA-BINDING PROTEIN 5", "d": [], "t": []}], "preferred_name": "RNA-BINDING PROTEIN 5", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42799:SF2", "l": "MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL PEPTIDE METHIONINE SULFOXIDE REDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16130:SF2", "l": "LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1", "d": [], "t": []}], "preferred_name": "LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15608:SF0", "l": "HIV TAT-SPECIFIC FACTOR 1", "d": [], "t": []}], "preferred_name": "HIV TAT-SPECIFIC FACTOR 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18829:SF0", "l": "PROTEIN YAE1 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN YAE1 HOMOLOG", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11011:SF119", "l": "FATTY ACYL-COA REDUCTASE 1", "d": [], "t": []}], "preferred_name": "FATTY ACYL-COA REDUCTASE 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45931", "l": "SI:CH211-59O9.10", "d": [], "t": []}], "preferred_name": "SI:CH211-59O9.10", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23299:SF58", "l": "METALLOTHIONEIN 1H-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "METALLOTHIONEIN 1H-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10217:SF380", "l": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 8", "d": [], "t": []}], "preferred_name": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 8", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10747:SF36", "l": "TRANSCRIPTION FACTOR COE4", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR COE4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23290:SF0", "l": "RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5", "d": [], "t": []}], "preferred_name": "RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21713:SF2", "l": "NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-2", "d": [], "t": []}], "preferred_name": "NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48425:SF1", "l": "KERATIN-ASSOCIATED PROTEIN 2-1", "d": [], "t": []}], "preferred_name": "KERATIN-ASSOCIATED PROTEIN 2-1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11239:SF14", "l": "DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12", "d": [], "t": []}], "preferred_name": "DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13453", "l": "KAT8 REGULATORY NSL COMPLEX SUBUNIT 2", "d": [], "t": []}], "preferred_name": "KAT8 REGULATORY NSL COMPLEX SUBUNIT 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR41404", "l": "SHIELDIN COMPLEX SUBUNIT 3", "d": [], "t": []}], "preferred_name": "SHIELDIN COMPLEX SUBUNIT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13153", "l": "CGTHBA PROTEIN  -14 GENE PROTEIN", "d": [], "t": []}], "preferred_name": "CGTHBA PROTEIN  -14 GENE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11645:SF61", "l": "PYRROLINE-5-CARBOXYLATE REDUCTASE 2", "d": [], "t": []}], "preferred_name": "PYRROLINE-5-CARBOXYLATE REDUCTASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF286", "l": "PROTOCADHERIN BETA-11", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN BETA-11", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17537:SF3", "l": "PROTEIN TOB2", "d": [], "t": []}], "preferred_name": "PROTEIN TOB2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11787:SF3", "l": "RAB GDP DISSOCIATION INHIBITOR ALPHA", "d": [], "t": []}], "preferred_name": "RAB GDP DISSOCIATION INHIBITOR ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24238:SF57", "l": "G-PROTEIN COUPLED RECEPTOR 83", "d": [], "t": []}], "preferred_name": "G-PROTEIN COUPLED RECEPTOR 83", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10336:SF36", "l": "1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4", "d": [], "t": []}], "preferred_name": "1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16453:SF9", "l": "GATOR COMPLEX PROTEIN MIOS", "d": [], "t": []}], "preferred_name": "GATOR COMPLEX PROTEIN MIOS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24247:SF207", "l": "MUSCARINIC ACETYLCHOLINE RECEPTOR M2", "d": [], "t": []}], "preferred_name": "MUSCARINIC ACETYLCHOLINE RECEPTOR M2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10918:SF4", "l": "HOMER PROTEIN HOMOLOG 3", "d": [], "t": []}], "preferred_name": "HOMER PROTEIN HOMOLOG 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24381", "l": "ZINC FINGER PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19842", "l": "G BETA-LIKE PROTEIN GBL", "d": [], "t": []}], "preferred_name": "G BETA-LIKE PROTEIN GBL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11486:SF41", "l": "FIBROBLAST GROWTH FACTOR 22", "d": [], "t": []}], "preferred_name": "FIBROBLAST GROWTH FACTOR 22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33721:SF1", "l": "TRANSMEMBRANE PROTEIN 255A", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 255A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22599:SF56", "l": "MOB-LIKE PROTEIN PHOCEIN", "d": [], "t": []}], "preferred_name": "MOB-LIKE PROTEIN PHOCEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46297", "l": "ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43795:SF17", "l": "1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12623", "l": "NGFI-A BINDING PROTEIN", "d": [], "t": []}], "preferred_name": "NGFI-A BINDING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48118", "l": "SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3", "d": [], "t": []}], "preferred_name": "SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11610:SF13", "l": "ENDOTHELIAL LIPASE", "d": [], "t": []}], "preferred_name": "ENDOTHELIAL LIPASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11510", "l": "MYO-INOSITOL-1 PHOSPHATE SYNTHASE", "d": [], "t": []}], "preferred_name": "MYO-INOSITOL-1 PHOSPHATE SYNTHASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR37354:SF1", "l": "CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1", "d": [], "t": []}], "preferred_name": "CHROMOSOME ALIGNMENT-MAINTAINING PHOSPHOPROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11353", "l": "CHAPERONIN", "d": [], "t": []}], "preferred_name": "CHAPERONIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36982:SF3", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 22", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 22", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13345:SF13", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47065", "l": "EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9", "d": [], "t": []}], "preferred_name": "EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44321", "l": "TRANSDUCIN BETA-LIKE PROTEIN 2", "d": [], "t": []}], "preferred_name": "TRANSDUCIN BETA-LIKE PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47193", "l": "CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "CATION CHANNEL SPERM-ASSOCIATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15896:SF7", "l": "PROTEIN GOLM2", "d": [], "t": []}], "preferred_name": "PROTEIN GOLM2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15607", "l": "SYNAPTONEMAL COMPLEX PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "SYNAPTONEMAL COMPLEX PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47004", "l": "F-BOX ONLY PROTEIN 24", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 24", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31180:SF2", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 107", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1051", "l": "Nucleoporins", "d": ["The nucleoporins are a family of proteins which are the constituent building blocks of the nuclear pore complex (NPC). The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the cell nucleus and the cytoplasm. Nuclear pores in turn allow the transport of water-soluble molecules across the nuclear envelope. Nucleoporins, a family of around 30 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nucleoporin 62 is the most abundant member of this family. Nucleoporins are able to transport molecules across the nuclear envelope at a very high rate. A single NPC is able to transport 60,000 protein molecules across the nuclear envelope every minute."], "t": []}], "preferred_name": "Nucleoporins", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11984:SF33", "l": "GAP JUNCTION ALPHA-1 PROTEIN", "d": [], "t": []}], "preferred_name": "GAP JUNCTION ALPHA-1 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45027:SF4", "l": "GLUTATHIONE HYDROLASE LIGHT CHAIN 1", "d": [], "t": []}], "preferred_name": "GLUTATHIONE HYDROLASE LIGHT CHAIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31466", "l": "GENE 5591-RELATED", "d": [], "t": []}], "preferred_name": "GENE 5591-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12289:SF76", "l": "FAILED AXON CONNECTIONS HOMOLOG", "d": [], "t": []}], "preferred_name": "FAILED AXON CONNECTIONS HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24086", "l": "NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A", "d": [], "t": []}], "preferred_name": "NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47980:SF42", "l": "RAS-RELATED PROTEIN RAB-13", "d": [], "t": []}], "preferred_name": "RAS-RELATED PROTEIN RAB-13", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24083", "l": "NUCLEAR HORMONE RECEPTOR", "d": [], "t": []}], "preferred_name": "NUCLEAR HORMONE RECEPTOR", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46143", "l": "CALPAIN-7", "d": [], "t": []}], "preferred_name": "CALPAIN-7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43880:SF11", "l": "ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH1B", "d": [], "t": []}], "preferred_name": "ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1116", "l": "ESCRT-I", "d": [], "t": []}], "preferred_name": "ESCRT-I", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24183:SF1", "l": "FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1", "d": [], "t": []}], "preferred_name": "FIBRONECTIN TYPE 3 AND ANKYRIN REPEAT DOMAINS PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12829:SF4", "l": "N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4", "d": [], "t": []}], "preferred_name": "N(6)-ADENINE-SPECIFIC METHYLTRANSFERASE METTL4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46820", "l": "HISTONE-LYSINE N-METHYLTRANSFERASE SETD7", "d": [], "t": []}], "preferred_name": "HISTONE-LYSINE N-METHYLTRANSFERASE SETD7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13395:SF6", "l": "SISTER CHROMATID COHESION PROTEIN DCC1", "d": [], "t": []}], "preferred_name": "SISTER CHROMATID COHESION PROTEIN DCC1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10885:SF1", "l": "ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE 2", "d": [], "t": []}], "preferred_name": "ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23351:SF13", "l": "BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3", "d": [], "t": []}], "preferred_name": "BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48415", "l": "GENE 525-RELATED", "d": [], "t": []}], "preferred_name": "GENE 525-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12019", "l": "LAMINA-ASSOCIATED POLYPEPTIDE  THYMOPOIETIN", "d": [], "t": []}], "preferred_name": "LAMINA-ASSOCIATED POLYPEPTIDE  THYMOPOIETIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11630:SF47", "l": "DNA HELICASE MCM8", "d": [], "t": []}], "preferred_name": "DNA HELICASE MCM8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13793:SF85", "l": "PEREGRIN", "d": [], "t": []}], "preferred_name": "PEREGRIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13173", "l": "WW DOMAIN BINDING PROTEIN 4", "d": [], "t": []}], "preferred_name": "WW DOMAIN BINDING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11871:SF1", "l": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 55 KDA REGULATORY SUBUNIT B BETA ISOFORM", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46479:SF1", "l": "BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2", "d": [], "t": []}], "preferred_name": "BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46481:SF4", "l": "ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4", "d": [], "t": []}], "preferred_name": "ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31296:SF1", "l": "MITOCHONDRIAL PROTEIN C2ORF69", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL PROTEIN C2ORF69", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44252", "l": "D-ERYTHRULOSE REDUCTASE", "d": [], "t": []}], "preferred_name": "D-ERYTHRULOSE REDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11601", "l": "CYSTEINE DESULFURYLASE FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "CYSTEINE DESULFURYLASE FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23101", "l": "RAB GDP/GTP EXCHANGE FACTOR", "d": [], "t": []}], "preferred_name": "RAB GDP/GTP EXCHANGE FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1985", "l": "Nuclear factor I family", "d": [], "t": []}], "preferred_name": "Nuclear factor I family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24390:SF43", "l": "ZINC FINGER PROTEIN 710", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 710", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21477", "l": "ZGC:172139", "d": [], "t": []}], "preferred_name": "ZGC:172139", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46453:SF4", "l": "PHD FINGER PROTEIN 24", "d": [], "t": []}], "preferred_name": "PHD FINGER PROTEIN 24", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10938", "l": "TRANSLATION INITIATION FACTOR IF-3", "d": [], "t": []}], "preferred_name": "TRANSLATION INITIATION FACTOR IF-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13091", "l": "AMPLIFIED IN BREAST CANCER 2-RELATED", "d": [], "t": []}], "preferred_name": "AMPLIFIED IN BREAST CANCER 2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32315:SF3", "l": "ADENINE PHOSPHORIBOSYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "ADENINE PHOSPHORIBOSYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11178", "l": "IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED", "d": [], "t": []}], "preferred_name": "IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24381:SF361", "l": "ZINC FINGER PROTEIN 77", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 77", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10841:SF20", "l": "SYNAPSIN-2", "d": [], "t": []}], "preferred_name": "SYNAPSIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3784", "l": "Thymosin beta family", "d": ["The Thymosin betas are a family of highly conserved polar 5 kDa peptides originally thought to be thymic hormones. Thymosin beta 4 as well as other members of this ubiquitous peptide family were identified as the main intracellular G-actin sequestering peptides, being present in high concentrations in almost every cell. Thymosins betas bind monomeric actin in a 1:1 complex and act as actin buffers, preventing polymerization into actin filaments but supplying a pool of actin monomers when the cell needs filaments."], "t": []}], "preferred_name": "Thymosin beta family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11792:SF15", "l": "S-ARRESTIN", "d": [], "t": []}], "preferred_name": "S-ARRESTIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24123:SF135", "l": "ANKYRIN REPEAT AND SOCS BOX PROTEIN 4", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT AND SOCS BOX PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15909:SF0", "l": "LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M", "d": [], "t": []}], "preferred_name": "LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:449", "l": "UDP-N-acetylglucosaminyltransferase subunits", "d": [], "t": []}], "preferred_name": "UDP-N-acetylglucosaminyltransferase subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:403", "l": "Ankyrin repeat domain containing", "d": ["Protein containing at least one ANK repeat, a conserved domain of approximately 33 amino acids, that was originally identified in ankyrin. It has been described as an L-shaped structure consisting of a beta-hairpin and two alpha-helices. Many ankyrin repeat regions are known to function as protein-protein interaction domains."], "t": []}], "preferred_name": "Ankyrin repeat domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23255", "l": "TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II", "d": [], "t": []}], "preferred_name": "TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44566:SF1", "l": "WD REPEAT-CONTAINING PROTEIN 25", "d": [], "t": []}], "preferred_name": "WD REPEAT-CONTAINING PROTEIN 25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16717:SF2", "l": "CYTOCHROME C OXIDASE SUBUNIT 8C, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "CYTOCHROME C OXIDASE SUBUNIT 8C, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23325", "l": "SERUM RESPONSE FACTOR-BINDING", "d": [], "t": []}], "preferred_name": "SERUM RESPONSE FACTOR-BINDING", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45993:SF4", "l": "B-CELL LYMPHOMA_LEUKEMIA 11B", "d": [], "t": []}], "preferred_name": "B-CELL LYMPHOMA_LEUKEMIA 11B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21580", "l": "SHIPPO-1-RELATED", "d": [], "t": []}], "preferred_name": "SHIPPO-1-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14678", "l": "PROLINE-RICH PROTEIN 35-RELATED", "d": [], "t": []}], "preferred_name": "PROLINE-RICH PROTEIN 35-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF661", "l": "ZINC FINGER PROTEIN 211", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 211", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19290:SF88", "l": "NEUROGENIC DIFFERENTIATION FACTOR 1", "d": [], "t": []}], "preferred_name": "NEUROGENIC DIFFERENTIATION FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10131:SF131", "l": "TNF RECEPTOR-ASSOCIATED FACTOR 6", "d": [], "t": []}], "preferred_name": "TNF RECEPTOR-ASSOCIATED FACTOR 6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17204", "l": "PRE-MRNA PROCESSING PROTEIN PRP39-RELATED", "d": [], "t": []}], "preferred_name": "PRE-MRNA PROCESSING PROTEIN PRP39-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48014:SF20", "l": "STE20-RELATED KINASE ADAPTER PROTEIN ALPHA", "d": [], "t": []}], "preferred_name": "STE20-RELATED KINASE ADAPTER PROTEIN ALPHA", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16124", "l": "MIS18-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "MIS18-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11360:SF119", "l": "MONOCARBOXYLATE TRANSPORTER 10", "d": [], "t": []}], "preferred_name": "MONOCARBOXYLATE TRANSPORTER 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24350:SF4", "l": "AURORA KINASE B", "d": [], "t": []}], "preferred_name": "AURORA KINASE B", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:777", "l": "Tropomyosins", "d": ["Tropomyosins are a large family of integral components of actin filaments that play a critical role in regulating the function of actin filaments in both muscle and nonmuscle cells. These proteins consist of rod-shaped coiled-coil hetero- or homo-dimers that lie along the α-helical groove of most actin filaments. Interaction occurs along the length of the actin filament, with dimers aligning in a head-to-tail fashion."], "t": []}], "preferred_name": "Tropomyosins", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:960", "l": "Origin recognition complex", "d": ["In molecular biology, ORC or origin recognition complex is a multi-subunit DNA binding complex (6 subunits) that binds in all eukaryotes in an ATP-dependent manner to origins of replication. The subunits of this complex are encoded by the ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6 genes. ORC is a central component for eukaryotic DNA replication, and binds chromatin at replication origins throughout the cell cycle. ORC directs DNA replication throughout the genome and is required for its initiation. ORC bound at replication origins serves as the foundation for assembly of the pre-replication complex (pre-RC), which includes Cdc6, Tah11 (aka Cdt1), and the Mcm2 - Mcm7 complex. Pre-RC assembly during G1 is required for replication licensing of chromosomes prior to DNA synthesis during S phase. Cell cycle -regulated phosphorylation of Orc2, Orc6, Cdc6, and MCM by the cyclin -dependent protein kinase Cdc28 regulates initiation of DNA replication, including blocking reinitiation in G2 / M phase.   In yeast, ORC also plays a role in the establishment of silencing at the mating-type loci Hidden MAT Left (HML) and Hidden MAT Right (HMR). ORC participates in the assembly of transcriptionally silent chromatin at HML and HMR by recruiting the Sir1 silencing protein to the HML and HMR silencers. Both Orc1 and Orc5 bind ATP, though only Orc1 has ATPase activity. The binding of ATP by Orc1 is required for ORC binding to DNA and is essential for cell viability. The ATPase activity of Orc1 is involved in formation of the pre-RC. ATP binding by Orc5 is crucial for the stability of ORC as a whole. Only the Orc1-5 subunits are required for origin binding; Orc6 is essential for maintenance of pre-RCs once formed. Interactions within ORC suggest that Orc2-3-6 may form a core complex."], "t": []}], "preferred_name": "Origin recognition complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19862", "l": "WD REPEAT-CONTAINING PROTEIN 48", "d": [], "t": []}], "preferred_name": "WD REPEAT-CONTAINING PROTEIN 48", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24006", "l": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE", "d": [], "t": []}], "preferred_name": "UBIQUITIN CARBOXYL-TERMINAL HYDROLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1604", "l": "BAF complex subunits", "d": [], "t": []}], "preferred_name": "BAF complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43329:SF81", "l": "SERINE HYDROLASE-LIKE PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "SERINE HYDROLASE-LIKE PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24377:SF244", "l": "ZINC FINGER PROTEIN 623", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 623", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14947", "l": "ZINC FINGER PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10985:SF15", "l": "TRANSCRIPTION FACTOR HES-2", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR HES-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43134", "l": "SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34035", "l": "TESTIS-EXPRESSED PROTEIN 47", "d": [], "t": []}], "preferred_name": "TESTIS-EXPRESSED PROTEIN 47", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18839", "l": "MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14499:SF65", "l": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD1", "d": [], "t": []}], "preferred_name": "BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45859:SF1", "l": "TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA", "d": [], "t": []}], "preferred_name": "TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13664:SF0", "l": "BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR", "d": [], "t": []}], "preferred_name": "BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1970", "l": "CREB3 transcription factor family", "d": [], "t": []}], "preferred_name": "CREB3 transcription factor family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44177:SF1", "l": "TETRATRICOPEPTIDE REPEAT PROTEIN 8", "d": [], "t": []}], "preferred_name": "TETRATRICOPEPTIDE REPEAT PROTEIN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12452:SF0", "l": "THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17", "d": [], "t": []}], "preferred_name": "THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10605:SF7", "l": "HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3B1", "d": [], "t": []}], "preferred_name": "HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 3B1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24340:SF31", "l": "HOMEOBOX PROTEIN NKX-6.1", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN NKX-6.1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21569", "l": "RIBOSOMAL PROTEIN S9", "d": [], "t": []}], "preferred_name": "RIBOSOMAL PROTEIN S9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15710:SF160", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF181", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF181", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13440:SF8", "l": "BLOC-1-RELATED COMPLEX SUBUNIT 6", "d": [], "t": []}], "preferred_name": "BLOC-1-RELATED COMPLEX SUBUNIT 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10947", "l": "PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47", "d": [], "t": []}], "preferred_name": "PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28593:SF1", "l": "METEORIN-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "METEORIN-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23266", "l": "IMMUNOGLOBULIN HEAVY CHAIN", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN HEAVY CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13359:SF2", "l": "LARGE RIBOSOMAL SUBUNIT PROTEIN ML40", "d": [], "t": []}], "preferred_name": "LARGE RIBOSOMAL SUBUNIT PROTEIN ML40", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22760:SF2", "l": "ALPHA-1,2-MANNOSYLTRANSFERASE ALG9", "d": [], "t": []}], "preferred_name": "ALPHA-1,2-MANNOSYLTRANSFERASE ALG9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24373:SF263", "l": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 29", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13140:SF369", "l": "UNCONVENTIONAL MYOSIN-VIIA", "d": [], "t": []}], "preferred_name": "UNCONVENTIONAL MYOSIN-VIIA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:81", "l": "Zinc fingers FYVE-type", "d": ["The FYVE zinc finger is named after four proteins that it has been found in: Fab1, YOTB/ZK632.12, Vac1, and EEA1. The FYVE finger has been shown to bind two zinc ions. The FYVE finger has eight potential zinc coordinating cysteine positions. Many members of this family also include two histidines in a motif R+HHC+XCG, where + represents a charged residue and X any residue. FYVE-type domains are divided into two known classes: FYVE domains that specifically bind to phosphatidylinositol 3-phosphate in lipid bilayers and FYVE-related domains of undetermined function."], "t": []}], "preferred_name": "Zinc fingers FYVE-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13289", "l": "PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22957:SF168", "l": "TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "TBC DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12722:SF2", "l": "PROTEIN FAM50A", "d": [], "t": []}], "preferred_name": "PROTEIN FAM50A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10035", "l": "T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN", "d": [], "t": []}], "preferred_name": "T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43884:SF11", "l": "VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "VERY LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28668", "l": "TRANSMEMBRANE PROTEIN 234", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 234", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24274:SF1", "l": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161", "d": [], "t": []}], "preferred_name": "CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 161", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15060:SF0", "l": "INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-15 RECEPTOR SUBUNIT ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3551", "l": "MAPK interacting serine/threonine kinase family", "d": [], "t": []}], "preferred_name": "MAPK interacting serine/threonine kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11537:SF126", "l": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 4", "d": [], "t": []}], "preferred_name": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:813", "l": "Protein tyrosine phosphatases receptor type", "d": [], "t": []}], "preferred_name": "Protein tyrosine phosphatases receptor type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14385", "l": "CXC CHEMOKINE LIGAND", "d": [], "t": []}], "preferred_name": "CXC CHEMOKINE LIGAND", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:485", "l": "Lysine demethylases", "d": [], "t": []}], "preferred_name": "Lysine demethylases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14604:SF5", "l": "F-BOX_WD REPEAT-CONTAINING PROTEIN 1A", "d": [], "t": []}], "preferred_name": "F-BOX_WD REPEAT-CONTAINING PROTEIN 1A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12395:SF9", "l": "DECAPPING AND EXORIBONUCLEASE PROTEIN", "d": [], "t": []}], "preferred_name": "DECAPPING AND EXORIBONUCLEASE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24345:SF43", "l": "INACTIVE SERINE_THREONINE-PROTEIN KINASE PLK5", "d": [], "t": []}], "preferred_name": "INACTIVE SERINE_THREONINE-PROTEIN KINASE PLK5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12228:SF8", "l": "TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 7-LIKE", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 7-LIKE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16231:SF5", "l": "COMM DOMAIN-CONTAINING PROTEIN 6", "d": [], "t": []}], "preferred_name": "COMM DOMAIN-CONTAINING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19957", "l": "SYNTAXIN", "d": [], "t": []}], "preferred_name": "SYNTAXIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11829:SF204", "l": "FORKHEAD BOX PROTEIN L1", "d": [], "t": []}], "preferred_name": "FORKHEAD BOX PROTEIN L1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15205:SF2", "l": "DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "DEATH EFFECTOR DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:584", "l": "DNAJ (HSP40) heat shock proteins", "d": ["In molecular biology, chaperone DnaJ, also known as Hsp40 (heat shock protein 40 kD), is a molecular chaperone protein. It is expressed in a wide variety of organisms from bacteria to humans."], "t": []}], "preferred_name": "DNAJ (HSP40) heat shock proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3870", "l": "BICD family cargo adaptors", "d": [], "t": []}], "preferred_name": "BICD family cargo adaptors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11595:SF60", "l": "ELONGATION FACTOR 1-BETA", "d": [], "t": []}], "preferred_name": "ELONGATION FACTOR 1-BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13413:SF0", "l": "YLP MOTIF-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "YLP MOTIF-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48015:SF17", "l": "SERINE_THREONINE-PROTEIN KINASE PAK 4", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE PAK 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47735:SF11", "l": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3", "d": [], "t": []}], "preferred_name": "POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15583:SF14", "l": "INTERLEUKIN-17 RECEPTOR D", "d": [], "t": []}], "preferred_name": "INTERLEUKIN-17 RECEPTOR D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24110:SF3", "l": "CENTROSOMAL PROTEIN OF 78 KDA", "d": [], "t": []}], "preferred_name": "CENTROSOMAL PROTEIN OF 78 KDA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14226:SF26", "l": "PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6", "d": [], "t": []}], "preferred_name": "PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3415", "l": "PIM kinase family", "d": ["The Pim kinases are a family of constitutively active serine/threonine kinases, widely associated with cell survival, proliferation, and migration."], "t": []}], "preferred_name": "PIM kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11742:SF40", "l": "MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB", "d": [], "t": []}], "preferred_name": "MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE IB", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15868", "l": "SIMILAR TO RIKEN CDNA 6430571L13 GENE, SIMILAR TO G20 PROTEIN", "d": [], "t": []}], "preferred_name": "SIMILAR TO RIKEN CDNA 6430571L13 GENE, SIMILAR TO G20 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43128:SF10", "l": "L-LACTATE DEHYDROGENASE A CHAIN", "d": [], "t": []}], "preferred_name": "L-LACTATE DEHYDROGENASE A CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12469", "l": "PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28622:SF1", "l": "SMALL INTEGRAL MEMBRANE PROTEIN 7", "d": [], "t": []}], "preferred_name": "SMALL INTEGRAL MEMBRANE PROTEIN 7", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11022", "l": "PEPTIDOGLYCAN RECOGNITION PROTEIN", "d": [], "t": []}], "preferred_name": "PEPTIDOGLYCAN RECOGNITION PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3601", "l": "N-Ank proteins", "d": ["N-Ank proteins are characterised by an N-Ank module (N-terminal amphipathic helix followed by ankyrin repeats) and coiled-coil domains. Despite the low sequence conservation between different N-Ank superfamily members, several have been shown to be share the ability to bind and shape membranes. The amphipathic helix is required for membrane binding while the ankyrin repeats sense membrane curverture. Coiled-coil domains allow for self-assembly."], "t": []}], "preferred_name": "N-Ank proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10464", "l": "UREA TRANSPORTER", "d": [], "t": []}], "preferred_name": "UREA TRANSPORTER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12864:SF54", "l": "SPRY DOMAIN-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "SPRY DOMAIN-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12015:SF92", "l": "FRACTALKINE", "d": [], "t": []}], "preferred_name": "FRACTALKINE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15224:SF1", "l": "NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5", "d": [], "t": []}], "preferred_name": "NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1675", "l": "Adaptor related protein complex 5", "d": [], "t": []}], "preferred_name": "Adaptor related protein complex 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21531:SF0", "l": "PROTEIN LTV1 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN LTV1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12021:SF11", "l": "THYMOSIN BETA-15A-RELATED", "d": [], "t": []}], "preferred_name": "THYMOSIN BETA-15A-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23341:SF4", "l": "HIGH MOBILITY GROUP PROTEIN HMGI-C", "d": [], "t": []}], "preferred_name": "HIGH MOBILITY GROUP PROTEIN HMGI-C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17615:SF7", "l": "PROTEIN ENTREP3", "d": [], "t": []}], "preferred_name": "PROTEIN ENTREP3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11394:SF139", "l": "TASTE RECEPTOR TYPE 2 MEMBER 19-RELATED", "d": [], "t": []}], "preferred_name": "TASTE RECEPTOR TYPE 2 MEMBER 19-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12665:SF12", "l": "ORM1-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "ORM1-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14241:SF3", "l": "INTERFERON-INDUCED PROTEIN 44", "d": [], "t": []}], "preferred_name": "INTERFERON-INDUCED PROTEIN 44", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15069:SF1", "l": "PROTEASOME ASSEMBLY CHAPERONE 1", "d": [], "t": []}], "preferred_name": "PROTEASOME ASSEMBLY CHAPERONE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11743:SF13", "l": "VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1", "d": [], "t": []}], "preferred_name": "VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46048:SF6", "l": "HYDROXYCARBOXYLIC ACID RECEPTOR 2", "d": [], "t": []}], "preferred_name": "HYDROXYCARBOXYLIC ACID RECEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19332:SF1", "l": "PEROXISOMAL MEMBRANE PROTEIN PEX13", "d": [], "t": []}], "preferred_name": "PEROXISOMAL MEMBRANE PROTEIN PEX13", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:816", "l": "Chitinases", "d": ["Chitinases (EC 3.2.1.14, chitodextrinase, 1,4-beta-poly-N-acetylglucosaminidase, poly-beta-glucosaminidase, beta-1,4-poly-N-acetyl glucosamidinase, poly glycanohydrolase, (1->4)-2-acetamido-2-deoxy-beta-D-glucan glycanohydrolase) are hydrolytic enzymes that break down glycosidic bonds in chitin.   As chitin is a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods), chitinases are generally found in organisms that either need to reshape their own chitin or dissolve and digest the chitin of fungi or animals."], "t": []}], "preferred_name": "Chitinases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF90", "l": "PROTOCADHERIN BETA-5", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN BETA-5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10784:SF0", "l": "EUKARYOTIC TRANSLATION INITIATION FACTOR 6", "d": [], "t": []}], "preferred_name": "EUKARYOTIC TRANSLATION INITIATION FACTOR 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43201:SF5", "l": "MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10104:SF18", "l": "STATHMIN-2", "d": [], "t": []}], "preferred_name": "STATHMIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24210:SF10", "l": "LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 2", "d": [], "t": []}], "preferred_name": "LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22939", "l": "SERINE PROTEASE FAMILY S1C HTRA-RELATED", "d": [], "t": []}], "preferred_name": "SERINE PROTEASE FAMILY S1C HTRA-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2276", "l": "Solute carrier family 68", "d": [], "t": []}], "preferred_name": "Solute carrier family 68", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14060", "l": "PROTEIN P13 MTCP-1", "d": [], "t": []}], "preferred_name": "PROTEIN P13 MTCP-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10694", "l": "LYSINE-SPECIFIC DEMETHYLASE", "d": [], "t": []}], "preferred_name": "LYSINE-SPECIFIC DEMETHYLASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF27", "l": "SERPIN H1", "d": [], "t": []}], "preferred_name": "SERPIN H1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45857:SF2", "l": "FORMIN-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "FORMIN-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11202:SF11", "l": "SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24012:SF742", "l": "RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 3", "d": [], "t": []}], "preferred_name": "RNA-BINDING MOTIF, SINGLE-STRANDED-INTERACTING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13793", "l": "PHD FINGER PROTEINS", "d": [], "t": []}], "preferred_name": "PHD FINGER PROTEINS", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13048", "l": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3", "d": [], "t": []}], "preferred_name": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23426", "l": "FERREDOXIN/ADRENODOXIN", "d": [], "t": []}], "preferred_name": "FERREDOXIN/ADRENODOXIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1868", "l": "MicroRNA MIR3179 family", "d": [], "t": []}], "preferred_name": "MicroRNA MIR3179 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12988", "l": "SPHINGOMYELIN PHOSPHODIESTERASE 4", "d": [], "t": []}], "preferred_name": "SPHINGOMYELIN PHOSPHODIESTERASE 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1373", "l": "Hedgehog signaling molecule family", "d": [], "t": []}], "preferred_name": "Hedgehog signaling molecule family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR42757:SF22", "l": "LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN", "d": [], "t": []}], "preferred_name": "LIMBIC SYSTEM-ASSOCIATED MEMBRANE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12461:SF43", "l": "HSPB1-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "HSPB1-ASSOCIATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1045", "l": "HAD Asp-based non-protein phosphatases", "d": [], "t": []}], "preferred_name": "HAD Asp-based non-protein phosphatases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23049", "l": "MYOSIN REGULATORY LIGHT CHAIN 2", "d": [], "t": []}], "preferred_name": "MYOSIN REGULATORY LIGHT CHAIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24103:SF397", "l": "E3 UBIQUITIN-PROTEIN LIGASE TRIM17", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE TRIM17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45752:SF37", "l": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3828", "l": "Signal transducer and activator of transcription family", "d": ["All the STAT transcription factors share similar N-terminal, coiled-coil, DNA-binding, linker, SH2, and transactivation domains. In general, activated JAKs phosphorylate the conserved tyrosine residue of one STAT monomer, which then binds to the SH2 domain of another monomer, driving a conformational change that enables STATs to translocate into the nucleus to initiate the transcription of target genes."], "t": []}], "preferred_name": "Signal transducer and activator of transcription family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21008:SF0", "l": "S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1", "d": [], "t": []}], "preferred_name": "S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13454:SF11", "l": "PROTEIN MCM10 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN MCM10 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:831", "l": "Phosphatidylinositol 3-kinase family", "d": ["Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the [HGNC] official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.  PI3Ks are a family of related intracellular signal transducer enzymes capable of phosphorylating the 3 position hydroxyl group of the inositol ring of phosphatidylinositol (PtdIns). The pathway, with oncogene PIK3CA and tumor suppressor PTEN, is implicated in insensitivity of cancer tumors to insulin and IGF1, in calorie restriction."], "t": []}], "preferred_name": "Phosphatidylinositol 3-kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1767", "l": "MicroRNA MIR95 family", "d": [], "t": []}], "preferred_name": "MicroRNA MIR95 family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1336", "l": "BRCA1 C complex", "d": ["BRCA1 forms a complex with RBBP8 and MRN (MRE11/RAD50/NBN) in a cell cycle-dependent manner during S and G2 phase of the cell cycle through the BRCT domains of BRCA1 binding to phosphorylated S327, a CDK phosphorylation site of RBBP8 in a phospho-SPxF motif. The <a href='http://www.genenames.org/data/genegroup/#!/group/1344'>MRN complex</a> also has other functions not related to its role in the BRCA1 C complex.  RBBP8 is required for DNA end resection at the initial step of homologous recombination (HR) dependent DSB repair CTIP promotes DNA end resection by interacting and stimulating the nuclease activity of the MRN complex. The complex formation of BRCA1-RBBP8-MRN is important for facilitating DSB resection to generate single-stranded DNA that is needed for HR-mediated DSB repair."], "t": []}], "preferred_name": "BRCA1 C complex", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11158:SF22", "l": "PRELI DOMAIN CONTAINING PROTEIN 3B", "d": [], "t": []}], "preferred_name": "PRELI DOMAIN CONTAINING PROTEIN 3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45903:SF1", "l": "GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13072", "l": "DYNACTIN 6", "d": [], "t": []}], "preferred_name": "DYNACTIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22175:SF1", "l": "SMALL ACIDIC PROTEIN", "d": [], "t": []}], "preferred_name": "SMALL ACIDIC PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3645", "l": "Natriuretic peptides", "d": ["The natriuretic peptides are a family of structurally related peptides which share a common, 17-membered, internal disulfide ring. Three major subtypes (A-, B-, and C-type natriuretic peptides) exist, and each is present in various tissues in multiple N- and C-terminally extended or shortened forms."], "t": []}], "preferred_name": "Natriuretic peptides", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14677:SF13", "l": "AN1-TYPE ZINC FINGER PROTEIN 2B", "d": [], "t": []}], "preferred_name": "AN1-TYPE ZINC FINGER PROTEIN 2B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23412:SF14", "l": "STEREOCILIN-RELATED", "d": [], "t": []}], "preferred_name": "STEREOCILIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF454", "l": "IMMUNOGLOBULIN LAMBDA VARIABLE 1-40-RELATED", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN LAMBDA VARIABLE 1-40-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45964:SF8", "l": "SIALATE:O-SULFOTRANSFERASE 1", "d": [], "t": []}], "preferred_name": "SIALATE:O-SULFOTRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11955:SF56", "l": "RETINOL-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "RETINOL-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1442", "l": "M24 metallopeptidase family", "d": ["The exopeptidases in this family require cocatalytic ions of cobalt or manganese."], "t": []}], "preferred_name": "M24 metallopeptidase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11932:SF173", "l": "CULLIN-1", "d": [], "t": []}], "preferred_name": "CULLIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12636", "l": "NEP1/MRA1", "d": [], "t": []}], "preferred_name": "NEP1/MRA1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46571:SF1", "l": "SORTING NEXIN-8", "d": [], "t": []}], "preferred_name": "SORTING NEXIN-8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24247:SF34", "l": "5-HYDROXYTRYPTAMINE RECEPTOR 1F", "d": [], "t": []}], "preferred_name": "5-HYDROXYTRYPTAMINE RECEPTOR 1F", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19879:SF7", "l": "PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1", "d": [], "t": []}], "preferred_name": "PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19441:SF16", "l": "PROTEIN WFDC9", "d": [], "t": []}], "preferred_name": "PROTEIN WFDC9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF491", "l": "IMMUNOGLOBULIN LAMBDA VARIABLE 2-18-RELATED", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN LAMBDA VARIABLE 2-18-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48015:SF39", "l": "TRAF2 AND NCK-INTERACTING PROTEIN KINASE", "d": [], "t": []}], "preferred_name": "TRAF2 AND NCK-INTERACTING PROTEIN KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48002:SF108", "l": "OLFACTORY RECEPTOR 4D9", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 4D9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22710", "l": "X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1  XRRA1", "d": [], "t": []}], "preferred_name": "X-RAY RADIATION RESISTANCE ASSOCIATED PROTEIN 1  XRRA1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22791:SF28", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF186", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF186", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46237", "l": "CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46350:SF3", "l": "RAS-LIKE PROTEIN FAMILY MEMBER 10A", "d": [], "t": []}], "preferred_name": "RAS-LIKE PROTEIN FAMILY MEMBER 10A", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12832:SF21", "l": "T-COMPLEX PROTEIN 11 X-LINKED PROTEIN 1-RELATED", "d": [], "t": []}], "preferred_name": "T-COMPLEX PROTEIN 11 X-LINKED PROTEIN 1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11827:SF46", "l": "SOLUTE CARRIER FAMILY 12 MEMBER 4", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 12 MEMBER 4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46881", "l": "PALMDELPHIN", "d": [], "t": []}], "preferred_name": "PALMDELPHIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14224:SF28", "l": "PRAME FAMILY MEMBER 10-RELATED", "d": [], "t": []}], "preferred_name": "PRAME FAMILY MEMBER 10-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23050:SF427", "l": "CALMODULIN-3", "d": [], "t": []}], "preferred_name": "CALMODULIN-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10517:SF15", "l": "FOLATE RECEPTOR ALPHA", "d": [], "t": []}], "preferred_name": "FOLATE RECEPTOR ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10489:SF611", "l": "C-C CHEMOKINE RECEPTOR TYPE 6", "d": [], "t": []}], "preferred_name": "C-C CHEMOKINE RECEPTOR TYPE 6", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1190", "l": "SNF2 related family", "d": ["Snf2-family proteins are so-called owing to the presence of a domain that is homologous to the helicase-like ATPase domain of the Saccharomyces cerevisiae Snf2 protein. This domain, the Snf2 domain, consists of two tandem RecA-like folds and contains seven conserved helicase-related sequence motifs that classify it as part of the Superfamily 2 (SF2) grouping of helicase-like proteins."], "t": []}], "preferred_name": "SNF2 related family", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10822", "l": "GLYPICAN", "d": [], "t": []}], "preferred_name": "GLYPICAN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10082:SF28", "l": "INTEGRIN BETA-1", "d": [], "t": []}], "preferred_name": "INTEGRIN BETA-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10046:SF24", "l": "LON PROTEASE HOMOLOG 2, PEROXISOMAL", "d": [], "t": []}], "preferred_name": "LON PROTEASE HOMOLOG 2, PEROXISOMAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11278:SF5", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN ES7", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN ES7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24376:SF130", "l": "ZINC FINGER PROTEIN 384", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 384", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32022:SF10", "l": "D-GLUTAMATE CYCLASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "D-GLUTAMATE CYCLASE, MITOCHONDRIAL", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11442:SF8", "l": "HEMOGLOBIN SUBUNIT MU", "d": [], "t": []}], "preferred_name": "HEMOGLOBIN SUBUNIT MU", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16675:SF154", "l": "MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE A-RELATED", "d": [], "t": []}], "preferred_name": "MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE A-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2176", "l": "Solute carrier family 25", "d": [], "t": []}], "preferred_name": "Solute carrier family 25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10882", "l": "DIPHTHINE SYNTHASE", "d": [], "t": []}], "preferred_name": "DIPHTHINE SYNTHASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24543:SF320", "l": "COAGULATION FACTOR VIII", "d": [], "t": []}], "preferred_name": "COAGULATION FACTOR VIII", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3706", "l": "TTK protein kinase family", "d": ["TTK, a central component of the mitotic spindle assembly checkpoint, is classed as a dual-specificity kinase as it can phosphorylate serine, threonine, and tyrosine residues but thus far, no biologically relevant substrate is known to be phosphorylated on tyrosine by TTK."], "t": []}], "preferred_name": "TTK protein kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14024:SF25", "l": "PERILIPIN-2", "d": [], "t": []}], "preferred_name": "PERILIPIN-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31333:SF3", "l": "PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3B", "d": [], "t": []}], "preferred_name": "PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1491", "l": "Cilia and flagella associated", "d": [], "t": []}], "preferred_name": "Cilia and flagella associated", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23349:SF63", "l": "FER3-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "FER3-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44269:SF1", "l": "DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7", "d": [], "t": []}], "preferred_name": "DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22957:SF360", "l": "TBC1 DOMAIN FAMILY MEMBER 17", "d": [], "t": []}], "preferred_name": "TBC1 DOMAIN FAMILY MEMBER 17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22923:SF118", "l": "COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4", "d": [], "t": []}], "preferred_name": "COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:926", "l": "Rhomboid family", "d": ["The rhomboid proteases are a family of enzymes that exist in almost all species. They are proteases : they cut the polypeptide chain of other proteins. This proteolytic cleavage is irreversible in cells, and an important type of cellular regulation. Although proteases are one of the earliest and best studied class of enzyme, rhomboids belong to a much more recently discovered type: the intramembrane proteases. What is unique about intramembrane proteases is that their active sites are buried in the lipid bilayer of cell membranes, and they cleave other transmembrane proteins within their transmembrane domains. About 30% of all proteins have transmembrane domains, and their regulated processing often has major biological consequences. Accordingly, rhomboids regulate many important cellular processes, and may be involved in a wide range of human diseases."], "t": []}], "preferred_name": "Rhomboid family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12153", "l": "SELENOPROTEIN O", "d": [], "t": []}], "preferred_name": "SELENOPROTEIN O", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10980:SF8", "l": "RHO GDP-DISSOCIATION INHIBITOR 3", "d": [], "t": []}], "preferred_name": "RHO GDP-DISSOCIATION INHIBITOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31020:SF1", "l": "TRANSMEMBRANE PROTEIN 174", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 174", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14728", "l": "PROTEIN AURORA BOREALIS", "d": [], "t": []}], "preferred_name": "PROTEIN AURORA BOREALIS", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:990", "l": "Histone deacetylases, class II", "d": [], "t": []}], "preferred_name": "Histone deacetylases, class II", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39235", "l": "PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y", "d": [], "t": []}], "preferred_name": "PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Y", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15497:SF1", "l": "3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE", "d": [], "t": []}], "preferred_name": "3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14503:SF4", "l": "LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M", "d": [], "t": []}], "preferred_name": "LARGE RIBOSOMAL SUBUNIT PROTEIN BL34M", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13321", "l": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18", "d": [], "t": []}], "preferred_name": "MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47966:SF72", "l": "GASTRICSIN", "d": [], "t": []}], "preferred_name": "GASTRICSIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3945", "l": "Microseminoprotein family", "d": [], "t": []}], "preferred_name": "Microseminoprotein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22960", "l": "MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A", "d": [], "t": []}], "preferred_name": "MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19290:SF96", "l": "OLIGODENDROCYTE TRANSCRIPTION FACTOR 3", "d": [], "t": []}], "preferred_name": "OLIGODENDROCYTE TRANSCRIPTION FACTOR 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39158", "l": "OS08G0560600 PROTEIN", "d": [], "t": []}], "preferred_name": "OS08G0560600 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR38493:SF1", "l": "SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "SFI1 SPINDLE BODY DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13743:SF115", "l": "NEUROBEACHIN-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "NEUROBEACHIN-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10271:SF4", "l": "INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 2", "d": [], "t": []}], "preferred_name": "INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47394:SF1", "l": "SMALL CELL ADHESION GLYCOPROTEIN", "d": [], "t": []}], "preferred_name": "SMALL CELL ADHESION GLYCOPROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13335", "l": "TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1", "d": [], "t": []}], "preferred_name": "TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11654", "l": "OLIGOPEPTIDE TRANSPORTER-RELATED", "d": [], "t": []}], "preferred_name": "OLIGOPEPTIDE TRANSPORTER-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14949:SF53", "l": "VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11567:SF25", "l": "PROTEIN FRA10AC1", "d": [], "t": []}], "preferred_name": "PROTEIN FRA10AC1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12604", "l": "KU AUTOANTIGEN DNA HELICASE", "d": [], "t": []}], "preferred_name": "KU AUTOANTIGEN DNA HELICASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10653:SF6", "l": "F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-3", "d": [], "t": []}], "preferred_name": "F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10485", "l": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13968:SF21", "l": "RNA-BINDING RALY-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "RNA-BINDING RALY-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23167:SF43", "l": "EH DOMAIN-BINDING PROTEIN 1", "d": [], "t": []}], "preferred_name": "EH DOMAIN-BINDING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:746", "l": "Solute carrier family 56, sideroflexins", "d": [], "t": []}], "preferred_name": "Solute carrier family 56, sideroflexins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12420", "l": "PHD FINGER PROTEIN", "d": [], "t": []}], "preferred_name": "PHD FINGER PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10671:SF30", "l": "CLAUDIN DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "CLAUDIN DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21580:SF21", "l": "O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2", "d": [], "t": []}], "preferred_name": "O(6)-METHYLGUANINE-INDUCED APOPTOSIS 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15012", "l": "APICAL PROTEIN/SHROOM-RELATED", "d": [], "t": []}], "preferred_name": "APICAL PROTEIN/SHROOM-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:772", "l": "Trafficking protein particle complex subunits", "d": [], "t": []}], "preferred_name": "Trafficking protein particle complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28676:SF2", "l": "ALK AND LTK LIGAND 2", "d": [], "t": []}], "preferred_name": "ALK AND LTK LIGAND 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21682", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 149", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 149", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11927:SF4", "l": "GALACTOSIDE ALPHA-(1,2)-FUCOSYLTRANSFERASE 1", "d": [], "t": []}], "preferred_name": "GALACTOSIDE ALPHA-(1,2)-FUCOSYLTRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14932:SF1", "l": "RAB-LIKE PROTEIN 6", "d": [], "t": []}], "preferred_name": "RAB-LIKE PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11486:SF20", "l": "FIBROBLAST GROWTH FACTOR 7", "d": [], "t": []}], "preferred_name": "FIBROBLAST GROWTH FACTOR 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF472", "l": "IMMUNOGLOBULIN KAPPA VARIABLE 3-20-RELATED", "d": [], "t": []}], "preferred_name": "IMMUNOGLOBULIN KAPPA VARIABLE 3-20-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34651:SF1", "l": "SIMILAR TO ENSANGP00000021391", "d": [], "t": []}], "preferred_name": "SIMILAR TO ENSANGP00000021391", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR33690", "l": "DUF4605 DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "DUF4605 DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11097:SF8", "l": "EXOSOME COMPLEX COMPONENT RRP42", "d": [], "t": []}], "preferred_name": "EXOSOME COMPLEX COMPONENT RRP42", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23354", "l": "NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED", "d": [], "t": []}], "preferred_name": "NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12442", "l": "DYNEIN INTERMEDIATE CHAIN", "d": [], "t": []}], "preferred_name": "DYNEIN INTERMEDIATE CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13944", "l": "AGAP007712-PA", "d": [], "t": []}], "preferred_name": "AGAP007712-PA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24278:SF20", "l": "VITAMIN K-DEPENDENT PROTEIN Z", "d": [], "t": []}], "preferred_name": "VITAMIN K-DEPENDENT PROTEIN Z", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF71", "l": "PROTOCADHERIN BETA-16", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN BETA-16", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11841:SF1", "l": "REELIN", "d": [], "t": []}], "preferred_name": "REELIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45782:SF4", "l": "MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31883:SF7", "l": "PROTEIN FRG2-RELATED", "d": [], "t": []}], "preferred_name": "PROTEIN FRG2-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14879:SF3", "l": "E3 UBIQUITIN-PROTEIN LIGASE RNF34", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE RNF34", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23233:SF51", "l": "SAL-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "SAL-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48099", "l": "C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED", "d": [], "t": []}], "preferred_name": "C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11946:SF109", "l": "VALINE--TRNA LIGASE", "d": [], "t": []}], "preferred_name": "VALINE--TRNA LIGASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45620:SF27", "l": "PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR", "d": [], "t": []}], "preferred_name": "PARATHYROID HORMONE_PARATHYROID HORMONE-RELATED PEPTIDE RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23171:SF2", "l": "MYOCARDIAL ZONULA ADHERENS PROTEIN", "d": [], "t": []}], "preferred_name": "MYOCARDIAL ZONULA ADHERENS PROTEIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21007", "l": "LIVER EXPRESSED ANTIMICROBIAL PEPTIDE 2", "d": [], "t": []}], "preferred_name": "LIVER EXPRESSED ANTIMICROBIAL PEPTIDE 2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21206:SF0", "l": "DNA REPLICATION COMPLEX GINS PROTEIN SLD5", "d": [], "t": []}], "preferred_name": "DNA REPLICATION COMPLEX GINS PROTEIN SLD5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR25464:SF3", "l": "E3 UBIQUITIN-PROTEIN LIGASE TRIM32", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE TRIM32", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16079:SF4", "l": "E3 UBIQUITIN-PROTEIN LIGASE CHFR", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE CHFR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1259", "l": "SNAG transcriptional repressors", "d": [], "t": []}], "preferred_name": "SNAG transcriptional repressors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31344", "l": "NUCLEAR PORE COMPLEX PROTEIN NUP205", "d": [], "t": []}], "preferred_name": "NUCLEAR PORE COMPLEX PROTEIN NUP205", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36683", "l": "CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1", "d": [], "t": []}], "preferred_name": "CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22747:SF14", "l": "NUCLEOPLASMIN-2", "d": [], "t": []}], "preferred_name": "NUCLEOPLASMIN-2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31716", "l": "PROTEIN FMC1 HOMOLOG", "d": [], "t": []}], "preferred_name": "PROTEIN FMC1 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13168", "l": "ASSOCIATE OF C-MYC  AMY-1", "d": [], "t": []}], "preferred_name": "ASSOCIATE OF C-MYC  AMY-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11055", "l": "BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16222:SF26", "l": "ADP-RIBOSYLHYDROLASE ARH1", "d": [], "t": []}], "preferred_name": "ADP-RIBOSYLHYDROLASE ARH1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23069:SF5", "l": "ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B", "d": [], "t": []}], "preferred_name": "ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45925", "l": "ZINC FINGER PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10454:SF26", "l": "CASPASE-10", "d": [], "t": []}], "preferred_name": "CASPASE-10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11373", "l": "DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE", "d": [], "t": []}], "preferred_name": "DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24072:SF99", "l": "RHO-RELATED GTP-BINDING PROTEIN RHOF", "d": [], "t": []}], "preferred_name": "RHO-RELATED GTP-BINDING PROTEIN RHOF", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22749", "l": "RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10075:SF55", "l": "CONTACTIN-2", "d": [], "t": []}], "preferred_name": "CONTACTIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11596:SF81", "l": "ALKALINE PHOSPHATASE, GERM CELL TYPE", "d": [], "t": []}], "preferred_name": "ALKALINE PHOSPHATASE, GERM CELL TYPE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:475", "l": "Non-coding RNAs", "d": ["A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The term small RNA (sRNA) is often used for short bacterial ncRNAs. The DNA sequence from which a non-coding RNA is transcribed is often called an RNA gene.  Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNA (tRNA) and ribosomal RNA (rRNA), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown, however recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional."], "t": []}], "preferred_name": "Non-coding RNAs", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44252:SF2", "l": "L-XYLULOSE REDUCTASE", "d": [], "t": []}], "preferred_name": "L-XYLULOSE REDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10725:SF78", "l": "DNA TRANSPOSASE THAP9", "d": [], "t": []}], "preferred_name": "DNA TRANSPOSASE THAP9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR39415", "l": "PROLINE-RICH PROTEIN 27", "d": [], "t": []}], "preferred_name": "PROLINE-RICH PROTEIN 27", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24347:SF440", "l": "CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1B", "d": [], "t": []}], "preferred_name": "CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23266:SF359", "l": "IG-LIKE DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "IG-LIKE DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR32379", "l": "GUANIDINOACETATE N-METHYLTRANSFERASE", "d": [], "t": []}], "preferred_name": "GUANIDINOACETATE N-METHYLTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24340:SF20", "l": "HOMEOBOX PROTEIN NKX-6.3", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN NKX-6.3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24332", "l": "HOMEOBOX PROTEIN CDX", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN CDX", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13479", "l": "30S RIBOSOMAL PROTEIN S18", "d": [], "t": []}], "preferred_name": "30S RIBOSOMAL PROTEIN S18", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23095:SF43", "l": "PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8C", "d": [], "t": []}], "preferred_name": "PARANEOPLASTIC ANTIGEN-LIKE PROTEIN 8C", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17503:SF0", "l": "SYNCOLLIN", "d": [], "t": []}], "preferred_name": "SYNCOLLIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13843:SF6", "l": "MICROTUBULE-ASSOCIATED PROTEIN 1A", "d": [], "t": []}], "preferred_name": "MICROTUBULE-ASSOCIATED PROTEIN 1A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1693", "l": "Macro domain containing", "d": [], "t": []}], "preferred_name": "Macro domain containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14463:SF5", "l": "LIPASE MATURATION FACTOR 2", "d": [], "t": []}], "preferred_name": "LIPASE MATURATION FACTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11085:SF12", "l": "NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6", "d": [], "t": []}], "preferred_name": "NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11843:SF19", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN ES12", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN ES12", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45710:SF15", "l": "C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER B", "d": [], "t": []}], "preferred_name": "C-TYPE LECTIN DOMAIN FAMILY 2 MEMBER B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10057", "l": "PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR", "d": [], "t": []}], "preferred_name": "PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24329:SF301", "l": "PAIRED MESODERM HOMEOBOX PROTEIN 2B", "d": [], "t": []}], "preferred_name": "PAIRED MESODERM HOMEOBOX PROTEIN 2B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:428", "l": "Glycosyltransferase family 2", "d": [], "t": []}], "preferred_name": "Glycosyltransferase family 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13360", "l": "ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1", "d": [], "t": []}], "preferred_name": "ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1098", "l": "Myosin heavy chains, class II", "d": ["Myosin-II isoforms are the major contractile proteins in muscle and also play several crucial roles in non-muscle contractility. Myosin-II molecules contain two motor domains and assemble into bipolar filaments."], "t": []}], "preferred_name": "Myosin heavy chains, class II", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22904:SF517", "l": "STRESS-INDUCED-PHOSPHOPROTEIN 1", "d": [], "t": []}], "preferred_name": "STRESS-INDUCED-PHOSPHOPROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36526:SF1", "l": "TRANSMEMBRANE PROTEIN 154", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE PROTEIN 154", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43570:SF9", "l": "ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2", "d": [], "t": []}], "preferred_name": "ALDEHYDE DEHYDROGENASE FAMILY 3 MEMBER A2", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43104:SF2", "l": "L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13966:SF19", "l": "NUCLEASE EXOG, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "NUCLEASE EXOG, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1899", "l": "WNK lysine deficient protein kinases", "d": [], "t": []}], "preferred_name": "WNK lysine deficient protein kinases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24364:SF17", "l": "TROPHOBLAST GLYCOPROTEIN", "d": [], "t": []}], "preferred_name": "TROPHOBLAST GLYCOPROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44080", "l": "E3 UBIQUITIN-PROTEIN LIGASE COP1", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE COP1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46392:SF1", "l": "DUAL SERINE_THREONINE AND TYROSINE PROTEIN KINASE", "d": [], "t": []}], "preferred_name": "DUAL SERINE_THREONINE AND TYROSINE PROTEIN KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15123:SF5", "l": "SECRETED AND TRANSMEMBRANE PROTEIN 1", "d": [], "t": []}], "preferred_name": "SECRETED AND TRANSMEMBRANE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47095", "l": "RING FINGER PROTEIN 222", "d": [], "t": []}], "preferred_name": "RING FINGER PROTEIN 222", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19331:SF22", "l": "DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN", "d": [], "t": []}], "preferred_name": "DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3830", "l": "Oligodendrocyte transcription factor family", "d": [], "t": []}], "preferred_name": "Oligodendrocyte transcription factor family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43798:SF5", "l": "MONOACYLGLYCEROL LIPASE ABHD6", "d": [], "t": []}], "preferred_name": "MONOACYLGLYCEROL LIPASE ABHD6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14107", "l": "WD REPEAT PROTEIN", "d": [], "t": []}], "preferred_name": "WD REPEAT PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3416", "l": "FET protein family", "d": ["Members of the FET protein family, consisting of FUS, EWSR1, and TAF15, bind to RNA and contribute to the control of transcription, RNA processing, and the cytoplasmic fates of messenger RNAs in metazoa. FET proteins can also bind DNA, which may be important in transcription and DNA damage responses. FET proteins are of medical interest because chromosomal rearrangements of their genes promote various sarcomas and because point mutations in FUS or TAF15 can cause neurodegenerative diseases such as amyotrophic lateral sclerosis and frontotemporal lobar dementia."], "t": []}], "preferred_name": "FET protein family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45799:SF1", "l": "RETICULON-4", "d": [], "t": []}], "preferred_name": "RETICULON-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26453:SF235", "l": "OLFACTORY RECEPTOR 2V2", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 2V2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10201:SF138", "l": "MATRIX METALLOPROTEINASE-24", "d": [], "t": []}], "preferred_name": "MATRIX METALLOPROTEINASE-24", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19972:SF15", "l": "SECRETAGOGIN", "d": [], "t": []}], "preferred_name": "SECRETAGOGIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14753", "l": "F-BOX ONLY PROTEIN 38", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 38", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20852", "l": "GLUTAMINE SYNTHETASE", "d": [], "t": []}], "preferred_name": "GLUTAMINE SYNTHETASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24271:SF62", "l": "KALLIKREIN-8", "d": [], "t": []}], "preferred_name": "KALLIKREIN-8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR25466", "l": "T-LYMPHOCYTE ACTIVATION ANTIGEN", "d": [], "t": []}], "preferred_name": "T-LYMPHOCYTE ACTIVATION ANTIGEN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35976", "l": "IQ DOMAIN-CONTAINING PROTEIN J", "d": [], "t": []}], "preferred_name": "IQ DOMAIN-CONTAINING PROTEIN J", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10819", "l": "PHOSPHOTRIESTERASE-RELATED", "d": [], "t": []}], "preferred_name": "PHOSPHOTRIESTERASE-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24356:SF171", "l": "RAC-ALPHA SERINE_THREONINE-PROTEIN KINASE", "d": [], "t": []}], "preferred_name": "RAC-ALPHA SERINE_THREONINE-PROTEIN KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12937", "l": "VACUOLAR PROTEIN SORTING 28, ISOFORM 2  VPS28", "d": [], "t": []}], "preferred_name": "VACUOLAR PROTEIN SORTING 28, ISOFORM 2  VPS28", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:602", "l": "Interleukin receptors", "d": ["An interleukin receptor is a cytokine receptor for interleukins."], "t": []}], "preferred_name": "Interleukin receptors", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10652", "l": "ADENYLYL CYCLASE-ASSOCIATED PROTEIN", "d": [], "t": []}], "preferred_name": "ADENYLYL CYCLASE-ASSOCIATED PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23346", "l": "TRANSLATIONAL ACTIVATOR GCN1-RELATED", "d": [], "t": []}], "preferred_name": "TRANSLATIONAL ACTIVATOR GCN1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22705", "l": "ZINC FINGER, ZZ DOMAIN CONTAINING 3", "d": [], "t": []}], "preferred_name": "ZINC FINGER, ZZ DOMAIN CONTAINING 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22884:SF473", "l": "HISTONE-LYSINE N-METHYLTRANSFERASE NSD3", "d": [], "t": []}], "preferred_name": "HISTONE-LYSINE N-METHYLTRANSFERASE NSD3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24390:SF260", "l": "ZINC FINGER PROTEIN 383-RELATED", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 383-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24379:SF68", "l": "ZINC FINGER PROTEIN 443", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 443", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47769", "l": "WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8", "d": [], "t": []}], "preferred_name": "WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR17985", "l": "SER/THR-RICH PROTEIN T10 IN DGCR REGION", "d": [], "t": []}], "preferred_name": "SER/THR-RICH PROTEIN T10 IN DGCR REGION", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13302", "l": "CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3", "d": [], "t": []}], "preferred_name": "CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22802:SF14", "l": "C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K", "d": [], "t": []}], "preferred_name": "C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:2261", "l": "Ceramide synthases", "d": [], "t": []}], "preferred_name": "Ceramide synthases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11700:SF37", "l": "SMALL RIBOSOMAL SUBUNIT PROTEIN US10", "d": [], "t": []}], "preferred_name": "SMALL RIBOSOMAL SUBUNIT PROTEIN US10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45682", "l": "AGAP008228-PA", "d": [], "t": []}], "preferred_name": "AGAP008228-PA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23214:SF1", "l": "NEUROFILAMENT HEAVY POLYPEPTIDE", "d": [], "t": []}], "preferred_name": "NEUROFILAMENT HEAVY POLYPEPTIDE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1489", "l": "LHFPL tetraspan proteins", "d": [], "t": []}], "preferred_name": "LHFPL tetraspan proteins", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34766:SF1", "l": "UPF0449 PROTEIN C19ORF25", "d": [], "t": []}], "preferred_name": "UPF0449 PROTEIN C19ORF25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22611", "l": "PROTEIN NAKED CUTICLE", "d": [], "t": []}], "preferred_name": "PROTEIN NAKED CUTICLE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF40", "l": "PROTOCADHERIN-19", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN-19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11461:SF30", "l": "HEPARIN COFACTOR 2", "d": [], "t": []}], "preferred_name": "HEPARIN COFACTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31043", "l": "NEPHROCYSTIN-4", "d": [], "t": []}], "preferred_name": "NEPHROCYSTIN-4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21634", "l": "RE13835P", "d": [], "t": []}], "preferred_name": "RE13835P", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16073", "l": "DCR DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "DCR DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3457", "l": "Dihydrofolate reductase family", "d": ["Dihydrofolate reductase (DHFR) activity is an important enzymatic function that resides within the one carbon metabolism (OCM) pathway. Its central role in cellular metabolism in support of cell division and proliferation has made DHFR an attractive and successful drug target. Methotrexate is a direct inhibitor of DHFR. There are two human genes capable of encoding dihydrofolate reductase: intron-containing DHFR and a retrogene, DHFR2, which shares 92% amino acid sequence identity with DHFR. Although DHFR2 is transcribed, targeted proteomics analysis found only a low abundance of translated protein in human embryonic heart and no evidence of DHFR2 protein in adult cells. DHFR2 functionality may lie at the RNA level."], "t": []}], "preferred_name": "Dihydrofolate reductase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48099:SF7", "l": "BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE 2, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE 2, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11742", "l": "MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED", "d": [], "t": []}], "preferred_name": "MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21017:SF11", "l": "PROTEIN NIPSNAP HOMOLOG 1", "d": [], "t": []}], "preferred_name": "PROTEIN NIPSNAP HOMOLOG 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12817:SF2", "l": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6A", "d": [], "t": []}], "preferred_name": "TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14742:SF0", "l": "RIBONUCLEASE P PROTEIN SUBUNIT P21", "d": [], "t": []}], "preferred_name": "RIBONUCLEASE P PROTEIN SUBUNIT P21", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22776:SF25", "l": "CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 6", "d": [], "t": []}], "preferred_name": "CKLF-LIKE MARVEL TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24103:SF637", "l": "TRIPARTITE MOTIF-CONTAINING PROTEIN 49-RELATED", "d": [], "t": []}], "preferred_name": "TRIPARTITE MOTIF-CONTAINING PROTEIN 49-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11571:SF123", "l": "GLUTATHIONE S-TRANSFERASE A4", "d": [], "t": []}], "preferred_name": "GLUTATHIONE S-TRANSFERASE A4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19303:SF18", "l": "TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4", "d": [], "t": []}], "preferred_name": "TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46985:SF2", "l": "APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD", "d": [], "t": []}], "preferred_name": "APOPTOSIS-ASSOCIATED SPECK-LIKE PROTEIN CONTAINING A CARD", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10270:SF313", "l": "TRANSCRIPTION FACTOR SOX-21", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR SOX-21", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10137:SF4", "l": "V-TYPE PROTON ATPASE SUBUNIT C 2", "d": [], "t": []}], "preferred_name": "V-TYPE PROTON ATPASE SUBUNIT C 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11955:SF89", "l": "FATTY ACID-BINDING PROTEIN, INTESTINAL", "d": [], "t": []}], "preferred_name": "FATTY ACID-BINDING PROTEIN, INTESTINAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23359:SF105", "l": "ADENYLATE KINASE 7", "d": [], "t": []}], "preferred_name": "ADENYLATE KINASE 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15016", "l": "BREAST CARCINOMA-AMPLIFIED SEQUENCE 1", "d": [], "t": []}], "preferred_name": "BREAST CARCINOMA-AMPLIFIED SEQUENCE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15836", "l": "PERIPHILIN 1", "d": [], "t": []}], "preferred_name": "PERIPHILIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13691", "l": "RIBOSOMAL PROTEIN L2", "d": [], "t": []}], "preferred_name": "RIBOSOMAL PROTEIN L2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45134:SF23", "l": "SUBFAMILY NOT NAMED", "d": [], "t": []}], "preferred_name": "SUBFAMILY NOT NAMED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43730:SF1", "l": "BETA-MANNOSIDASE", "d": [], "t": []}], "preferred_name": "BETA-MANNOSIDASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11793:SF10", "l": "TRANSCRIPTION FACTOR 4", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14942:SF0", "l": "U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN", "d": [], "t": []}], "preferred_name": "U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35673", "l": "UPF0500 PROTEIN C1ORF216", "d": [], "t": []}], "preferred_name": "UPF0500 PROTEIN C1ORF216", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22809", "l": "METHYLTRANSFERASE-RELATED", "d": [], "t": []}], "preferred_name": "METHYLTRANSFERASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11675:SF28", "l": "POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9", "d": [], "t": []}], "preferred_name": "POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15603:SF1", "l": "METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1", "d": [], "t": []}], "preferred_name": "METASTASIS-ASSOCIATED IN COLON CANCER PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10125:SF4", "l": "P2X PURINOCEPTOR 2", "d": [], "t": []}], "preferred_name": "P2X PURINOCEPTOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24301:SF2", "l": "THROMBOXANE-A SYNTHASE", "d": [], "t": []}], "preferred_name": "THROMBOXANE-A SYNTHASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1032", "l": "Cullins", "d": ["Cullins are a family of hydrophobic proteins providing a scaffold for ubiquitin ligases (E3). All eukaryotes appear to have cullins. They combine with RING proteins to form Cullin-RING ubiquitin ligases (CRLs) that are highly diverse and play a role in myriad cellular processes.   The human genome contains eight cullin genes  CUL1, part of SCF complex  CUL2, part of ECS complex ( Elongin C - CUL2 - SOCS-box )  CUL3, part of CUL3-BTB complex  CUL4A  CUL4B  CUL5  CUL7  CUL9, also known as PARC  There is also a more distant member called ANAPC2 (or APC2), part of the Anaphase-promoting complex.  CUL1, 2, 3, 4A, 4B, 5 and 7 each form part of a multi-subunit ubiquitin complex.  Cullin-RING ubiquitin ligases (CRLs), such as Cul1 (SCF) play an essential role in targeting proteins for ubiquitin-mediated destruction; as such, they are diverse in terms of composition and function, regulating many different processes from glucose sensing and DNA replication to limb patterning and circadian rhythms. The catalytic core of CRLs consists of a RING protein and a cullin family member. For Cul1, the C-terminal cullin-homology domain binds the RING protein. The RING protein appears to function as a docking site for ubiquitin-conjugating enzymes (E2s). Other proteins contain a cullin-homology domain, such as CUL9, also known as p53 cytoplasmic anchor PARC, and the ANAPC2 subunit of the anaphase-promoting complex/cyclosome; both CUL9 and ANAPC2 have ubiquitin ligase activity. The N-terminal region of cullins is more variable, and is used to interact with specific adaptor proteins.   With the exception of ANAPC2, each member of the cullin family is modified by Nedd8 and several cullins function in Ubiquitin-dependent proteolysis, a process in which the 26S proteasome recognises and subsequently degrades a target protein tagged with K48-linked poly-ubiquitin chains. Nedd8CUL1-F-box protein) E3 Ub ligase complex in Saccharomyces cerevisiae (Baker's yeast), and Nedd8 modification has now emerged as a regulatory pathway of fundamental importance for cell cycle control and for embryogenesis in metazoans. The only identified Nedd8 substrates are cullins. Neddylation results in covalent conjugation of a Nedd8 moiety onto a conserved cullin lysine residue."], "t": []}], "preferred_name": "Cullins", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24169:SF18", "l": "TRANSCRIPTION FACTOR RELB", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION FACTOR RELB", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11211:SF11", "l": "IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-6", "d": [], "t": []}], "preferred_name": "IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX-6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43294:SF1", "l": "POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2", "d": [], "t": []}], "preferred_name": "POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46576:SF1", "l": "BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN", "d": [], "t": []}], "preferred_name": "BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23267:SF452", "l": "IG-LIKE DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "IG-LIKE DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24173:SF78", "l": "PROTEIN FEM-1 HOMOLOG B", "d": [], "t": []}], "preferred_name": "PROTEIN FEM-1 HOMOLOG B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24406:SF6", "l": "ZINC FINGER X-CHROMOSOMAL PROTEIN", "d": [], "t": []}], "preferred_name": "ZINC FINGER X-CHROMOSOMAL PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23404", "l": "MOLYBDOPTERIN SYNTHASE RELATED", "d": [], "t": []}], "preferred_name": "MOLYBDOPTERIN SYNTHASE RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12876:SF28", "l": "PROTEIN KHNYN", "d": [], "t": []}], "preferred_name": "PROTEIN KHNYN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21213", "l": "GEO09665P1-RELATED", "d": [], "t": []}], "preferred_name": "GEO09665P1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14699", "l": "STI2 PROTEIN-RELATED", "d": [], "t": []}], "preferred_name": "STI2 PROTEIN-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45915", "l": "TRANSCRIPTION INTERMEDIARY FACTOR", "d": [], "t": []}], "preferred_name": "TRANSCRIPTION INTERMEDIARY FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24068:SF330", "l": "UBIQUITIN-CONJUGATING ENZYME E2 D2", "d": [], "t": []}], "preferred_name": "UBIQUITIN-CONJUGATING ENZYME E2 D2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19051:SF34", "l": "KERATIN-ASSOCIATED PROTEIN 27-1", "d": [], "t": []}], "preferred_name": "KERATIN-ASSOCIATED PROTEIN 27-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11229", "l": "50S RIBOSOMAL PROTEIN L3", "d": [], "t": []}], "preferred_name": "50S RIBOSOMAL PROTEIN L3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR36868", "l": "NUTRITIONALLY-REGULATED ADIPOSE AND CARDIAC ENRICHED PROTEIN HOMOLOG", "d": [], "t": []}], "preferred_name": "NUTRITIONALLY-REGULATED ADIPOSE AND CARDIAC ENRICHED PROTEIN HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22904", "l": "TPR REPEAT CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "TPR REPEAT CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19282:SF44", "l": "CD82 ANTIGEN", "d": [], "t": []}], "preferred_name": "CD82 ANTIGEN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12616", "l": "VACUOLAR PROTEIN SORTING VPS41", "d": [], "t": []}], "preferred_name": "VACUOLAR PROTEIN SORTING VPS41", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46523", "l": "DCTP PYROPHOSPHATASE 1", "d": [], "t": []}], "preferred_name": "DCTP PYROPHOSPHATASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3777", "l": "VRK serine/threonine kinase family", "d": [], "t": []}], "preferred_name": "VRK serine/threonine kinase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24082:SF42", "l": "THYROID HORMONE RECEPTOR ALPHA", "d": [], "t": []}], "preferred_name": "THYROID HORMONE RECEPTOR ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47415", "l": "PROTEIN FAM47B", "d": [], "t": []}], "preferred_name": "PROTEIN FAM47B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43788:SF8", "l": "DNA-BINDING PROTEIN SMUBP-2", "d": [], "t": []}], "preferred_name": "DNA-BINDING PROTEIN SMUBP-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11081:SF8", "l": "EXONUCLEASE 1", "d": [], "t": []}], "preferred_name": "EXONUCLEASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16483:SF2", "l": "GASTROKINE-3", "d": [], "t": []}], "preferred_name": "GASTROKINE-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10153:SF41", "l": "INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4", "d": [], "t": []}], "preferred_name": "INTERMEDIATE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16803:SF0", "l": "HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA", "d": [], "t": []}], "preferred_name": "HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT GAMMA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31254:SF1", "l": "TEKTIN BUNDLE-INTERACTING PROTEIN 1", "d": [], "t": []}], "preferred_name": "TEKTIN BUNDLE-INTERACTING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16231", "l": "COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14897:SF5", "l": "WD REPEAT AND COILED-COIL-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "WD REPEAT AND COILED-COIL-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24060:SF23", "l": "METABOTROPIC GLUTAMATE RECEPTOR 4", "d": [], "t": []}], "preferred_name": "METABOTROPIC GLUTAMATE RECEPTOR 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10663:SF314", "l": "IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "IQ MOTIF AND SEC7 DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12289:SF30", "l": "METAXIN-3", "d": [], "t": []}], "preferred_name": "METAXIN-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21026", "l": "39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "39S RIBOSOMAL PROTEIN L32, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24014", "l": "2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13866:SF17", "l": "TESTICAN-1", "d": [], "t": []}], "preferred_name": "TESTICAN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14084:SF0", "l": "KYNURENINASE", "d": [], "t": []}], "preferred_name": "KYNURENINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20922:SF13", "l": "DNL-TYPE ZINC FINGER PROTEIN", "d": [], "t": []}], "preferred_name": "DNL-TYPE ZINC FINGER PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45890:SF1", "l": "AARF DOMAIN CONTAINING KINASE 2", "d": [], "t": []}], "preferred_name": "AARF DOMAIN CONTAINING KINASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:136", "l": "Zinc fingers CXXC-type", "d": ["This domain contains eight conserved cysteine residues that bind to two zinc ions. The CXXC domain is found in a variety of chromatin-associated proteins. This domain binds to non-methylated CpG dinucleotides. The domain is characterised by two CGXCXXC repeats. The RecQ helicase has a single repeat that also binds to zinc, but this has not been included in this family. The DNA binding interface has been identified by NMR."], "t": []}], "preferred_name": "Zinc fingers CXXC-type", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31554", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 184", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 184", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45774:SF5", "l": "BTB_POZ DOMAIN-CONTAINING PROTEIN 6", "d": [], "t": []}], "preferred_name": "BTB_POZ DOMAIN-CONTAINING PROTEIN 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15727", "l": "RING FINGER PROTEIN 214", "d": [], "t": []}], "preferred_name": "RING FINGER PROTEIN 214", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11724:SF1", "l": "LEPTIN", "d": [], "t": []}], "preferred_name": "LEPTIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR20952", "l": "ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN", "d": [], "t": []}], "preferred_name": "ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19957:SF36", "l": "SYNTAXIN-2", "d": [], "t": []}], "preferred_name": "SYNTAXIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14948:SF1", "l": "TRAFFICKING REGULATOR OF GLUT4 1", "d": [], "t": []}], "preferred_name": "TRAFFICKING REGULATOR OF GLUT4 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:755", "l": "Sp transcription factors", "d": [], "t": []}], "preferred_name": "Sp transcription factors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13220:SF12", "l": "CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3-RELATED", "d": [], "t": []}], "preferred_name": "CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 3-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14199", "l": "NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "NEUROBLASTOMA BREAKPOINT FAMILY MEMBER 6-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11040:SF221", "l": "ZINC TRANSPORTER ZIP3", "d": [], "t": []}], "preferred_name": "ZINC TRANSPORTER ZIP3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31393", "l": "C5ORF31", "d": [], "t": []}], "preferred_name": "C5ORF31", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46294:SF1", "l": "HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2", "d": [], "t": []}], "preferred_name": "HOMEOBOX EVEN-SKIPPED HOMOLOG PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23089:SF45", "l": "ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1", "d": [], "t": []}], "preferred_name": "ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10845:SF277", "l": "REGULATOR OF G-PROTEIN SIGNALING 20", "d": [], "t": []}], "preferred_name": "REGULATOR OF G-PROTEIN SIGNALING 20", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28642:SF1", "l": "MEIOSIS 1 ARREST PROTEIN", "d": [], "t": []}], "preferred_name": "MEIOSIS 1 ARREST PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18964:SF149", "l": "BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE", "d": [], "t": []}], "preferred_name": "BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15976:SF14", "l": "CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1", "d": [], "t": []}], "preferred_name": "CONSTITUTIVE COACTIVATOR OF PPAR-GAMMA-LIKE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45885", "l": "CELL DIVISION CYCLE 5-LIKE PROTEIN", "d": [], "t": []}], "preferred_name": "CELL DIVISION CYCLE 5-LIKE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12170:SF6", "l": "E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5B", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN TRANSFERASE RMND5B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10556:SF37", "l": "3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2", "d": [], "t": []}], "preferred_name": "3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15680", "l": "RIBOSOMAL PROTEIN L19", "d": [], "t": []}], "preferred_name": "RIBOSOMAL PROTEIN L19", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18860:SF7", "l": "14-3-3 PROTEIN ZETA_DELTA", "d": [], "t": []}], "preferred_name": "14-3-3 PROTEIN ZETA_DELTA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24300:SF400", "l": "CYTOCHROME P450 2C9", "d": [], "t": []}], "preferred_name": "CYTOCHROME P450 2C9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24104", "l": "E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22848:SF2", "l": "WD40 REPEAT-CONTAINING PROTEIN SMU1", "d": [], "t": []}], "preferred_name": "WD40 REPEAT-CONTAINING PROTEIN SMU1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11005", "l": "LYSOSOMAL ACID LIPASE-RELATED", "d": [], "t": []}], "preferred_name": "LYSOSOMAL ACID LIPASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45617:SF7", "l": "TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33", "d": [], "t": []}], "preferred_name": "TRANSFORMING GROWTH FACTOR BETA ACTIVATOR LRRC33", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12839", "l": "NONSENSE-MEDIATED MRNA DECAY PROTEIN 2  UP-FRAMESHIFT SUPPRESSOR 2", "d": [], "t": []}], "preferred_name": "NONSENSE-MEDIATED MRNA DECAY PROTEIN 2  UP-FRAMESHIFT SUPPRESSOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45973:SF30", "l": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 42", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 42", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11482:SF4", "l": "ANTIZYME INHIBITOR 2", "d": [], "t": []}], "preferred_name": "ANTIZYME INHIBITOR 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46489", "l": "STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "STEROIDOGENIC ACUTE REGULATORY PROTEIN, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22736:SF2", "l": "COILED-COIL DOMAIN-CONTAINING PROTEIN 66", "d": [], "t": []}], "preferred_name": "COILED-COIL DOMAIN-CONTAINING PROTEIN 66", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3776", "l": "MAP4K family (GCK-I subfamily)", "d": ["The mitogen-activated kinase kinase kinase kinases (MAP4Ks) are split across two subfamilies. The GCK-I subfamily of Ste20 kinases comprises four MAP4Ks that activate the JNK/SAPK pathway."], "t": []}], "preferred_name": "MAP4K family (GCK-I subfamily)", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48018:SF13", "l": "OLFACTORY RECEPTOR 8K5", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 8K5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11773:SF1", "l": "GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24147:SF59", "l": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 18B", "d": [], "t": []}], "preferred_name": "ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 18B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48099:SF1", "l": "C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC", "d": [], "t": []}], "preferred_name": "C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR44984:SF1", "l": "SERINE_THREONINE-PROTEIN KINASE NEK3", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE NEK3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13123:SF8", "l": "F-BOX ONLY PROTEIN 25", "d": [], "t": []}], "preferred_name": "F-BOX ONLY PROTEIN 25", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21250", "l": "PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG", "d": [], "t": []}], "preferred_name": "PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23232:SF67", "l": "ZINC FINGER PROTEIN 738", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 738", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46615", "l": "ARYLSULFATASE K", "d": [], "t": []}], "preferred_name": "ARYLSULFATASE K", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3626", "l": "Spectrin repeat containing", "d": ["The spectrin superfamily of proteins function to connect cytoskeletal elements to each other, the cell membrane, and the nucleus. The signature domain is the spectrin repeat, a 106–122-amino-acid segment comprising three α-helices. α-actinin is considered to be the ancestral protein and functions to cross-link actin filaments. It then evolved to generate spectrin and dystrophin that function to link the actin cytoskeleton to the cell membrane, as well as the spectraplakins and plakins that link cytoskeletal elements to each other and to junctional complexes. A final class comprises the nesprins, which are able to bind to the nuclear membrane."], "t": []}], "preferred_name": "Spectrin repeat containing", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23065:SF18", "l": "PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3", "d": [], "t": []}], "preferred_name": "PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24381:SF434", "l": "ZINC FINGER PROTEIN 436", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 436", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21021", "l": "GAF/PUTATIVE CYTOSKELETAL PROTEIN", "d": [], "t": []}], "preferred_name": "GAF/PUTATIVE CYTOSKELETAL PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15104", "l": "DIHYDROPTERIDINE REDUCTASE", "d": [], "t": []}], "preferred_name": "DIHYDROPTERIDINE REDUCTASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24115:SF445", "l": "KINESIN-LIKE PROTEIN KIF7", "d": [], "t": []}], "preferred_name": "KINESIN-LIKE PROTEIN KIF7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45721:SF2", "l": "LAMIN-B2", "d": [], "t": []}], "preferred_name": "LAMIN-B2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46877:SF16", "l": "EPHRIN TYPE-A RECEPTOR 10", "d": [], "t": []}], "preferred_name": "EPHRIN TYPE-A RECEPTOR 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22776:SF9", "l": "PLASMOLIPIN", "d": [], "t": []}], "preferred_name": "PLASMOLIPIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24072:SF100", "l": "RHO-RELATED GTP-BINDING PROTEIN RHOC", "d": [], "t": []}], "preferred_name": "RHO-RELATED GTP-BINDING PROTEIN RHOC", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22237:SF1", "l": "APC MEMBRANE RECRUITMENT PROTEIN 2", "d": [], "t": []}], "preferred_name": "APC MEMBRANE RECRUITMENT PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:570", "l": "Proteoglycans", "d": ["Protein containing one or more covalently linked and usually sulfated glycosaminoglycans, (e.g., chondroitin sulfate, dermatan sulfate, heparan sulfate, heparin, keratan sulfate). Glycosaminoglycans are polysaccharides made of repeating disaccharides (usually 40-100 times), which consist of uronic acid (or galactose) and hexosamines. Aggrecan, for example, is the major component in articular cartilage."], "t": []}], "preferred_name": "Proteoglycans", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11846:SF2", "l": "ADENYLOSUCCINATE SYNTHETASE ISOZYME 1", "d": [], "t": []}], "preferred_name": "ADENYLOSUCCINATE SYNTHETASE ISOZYME 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23222:SF1", "l": "PROHIBITIN-2", "d": [], "t": []}], "preferred_name": "PROHIBITIN-2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31367:SF0", "l": "CYTOSOLIC 5'-NUCLEOTIDASE 1B", "d": [], "t": []}], "preferred_name": "CYTOSOLIC 5'-NUCLEOTIDASE 1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15672", "l": "CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR18860:SF28", "l": "14-3-3 PROTEIN BETA_ALPHA", "d": [], "t": []}], "preferred_name": "14-3-3 PROTEIN BETA_ALPHA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10540:SF8", "l": "COP9 SIGNALOSOME COMPLEX SUBUNIT 6", "d": [], "t": []}], "preferred_name": "COP9 SIGNALOSOME COMPLEX SUBUNIT 6", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:828", "l": "Ferlin family", "d": [], "t": []}], "preferred_name": "Ferlin family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15157:SF5", "l": "UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN", "d": [], "t": []}], "preferred_name": "UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:445", "l": "Oligosaccharyltransferase complex subunits", "d": ["Oligosaccharyltransferase or OST ( EC 2.4.1.119 ) is a membrane protein complex that transfers a 14- sugar oligosaccharide from dolichol to nascent protein. It is a type of glycosyltransferase. The sugar Glc 3Man 9GlcNAc 2 (where Glc= Glucose, Man= Mannose, and GlcNAc= N-acetylglucosamine ) is attached to an asparagine (Asn) residue in the sequence Asn-X- Ser or Asn-X- Thr where X is any amino acid except proline. This sequence is called a glycosylation sequon. The reaction catalyzed by OST is the central step in the N -linked glycosylation pathway."], "t": []}], "preferred_name": "Oligosaccharyltransferase complex subunits", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24085:SF1", "l": "NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1", "d": [], "t": []}], "preferred_name": "NUCLEAR RECEPTOR SUBFAMILY 4 GROUP A MEMBER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46698", "l": "CROSSVEINLESS 2", "d": [], "t": []}], "preferred_name": "CROSSVEINLESS 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21568:SF0", "l": "TRNA PSEUDOURIDINE SYNTHASE PUS10", "d": [], "t": []}], "preferred_name": "TRNA PSEUDOURIDINE SYNTHASE PUS10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13620", "l": "3-5 EXONUCLEASE", "d": [], "t": []}], "preferred_name": "3-5 EXONUCLEASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46186:SF1", "l": "CYSTATIN-D", "d": [], "t": []}], "preferred_name": "CYSTATIN-D", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR31164", "l": "RAD52 MOTIF-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "RAD52 MOTIF-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28620", "l": "CENTROMERE PROTEIN V", "d": [], "t": []}], "preferred_name": "CENTROMERE PROTEIN V", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23268:SF42", "l": "T CELL RECEPTOR BETA VARIABLE 10-1-RELATED", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA VARIABLE 10-1-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12566", "l": "CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN  CPEB", "d": [], "t": []}], "preferred_name": "CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN  CPEB", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10615:SF73", "l": "HISTONE ACETYLTRANSFERASE KAT6B", "d": [], "t": []}], "preferred_name": "HISTONE ACETYLTRANSFERASE KAT6B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:986", "l": "Desumoylating isopeptidases", "d": [], "t": []}], "preferred_name": "Desumoylating isopeptidases", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12436:SF38", "l": "SAC3 DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "SAC3 DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15860:SF2", "l": "RING FINGER AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "RING FINGER AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24028:SF46", "l": "PROTOCADHERIN-8", "d": [], "t": []}], "preferred_name": "PROTOCADHERIN-8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13094:SF1", "l": "NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10", "d": [], "t": []}], "preferred_name": "NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1729", "l": "Ribosome biogenesis factors", "d": [], "t": []}], "preferred_name": "Ribosome biogenesis factors", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46780:SF23", "l": "PROTEIN EVA-1 HOMOLOG A", "d": [], "t": []}], "preferred_name": "PROTEIN EVA-1 HOMOLOG A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24383:SF14", "l": "ZINC FINGER PROTEIN 579", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 579", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24369:SF170", "l": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3", "d": [], "t": []}], "preferred_name": "LEUCINE-RICH REPEAT-CONTAINING PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24264:SF42", "l": "TISSUE-TYPE PLASMINOGEN ACTIVATOR", "d": [], "t": []}], "preferred_name": "TISSUE-TYPE PLASMINOGEN ACTIVATOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23268:SF86", "l": "T CELL RECEPTOR BETA VARIABLE 6-8-RELATED", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR BETA VARIABLE 6-8-RELATED", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22306", "l": "CHROMOSOME 7 OPEN READING FRAME 50", "d": [], "t": []}], "preferred_name": "CHROMOSOME 7 OPEN READING FRAME 50", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14689", "l": "PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13273", "l": "ANAMORSIN", "d": [], "t": []}], "preferred_name": "ANAMORSIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35068", "l": "BEN DOMAIN-CONTAINING PROTEIN 7", "d": [], "t": []}], "preferred_name": "BEN DOMAIN-CONTAINING PROTEIN 7", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11494", "l": "CYTOTOXIC T-LYMPHOCYTE PROTEIN", "d": [], "t": []}], "preferred_name": "CYTOTOXIC T-LYMPHOCYTE PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3579", "l": "Piezo type mechanosensitive ion channel components", "d": ["Piezos are the largest known pore-forming multimeric (individual subunits arranged as trimers) ion channels, with each subunit composed of ∼2,500 amino acids and containing 30–40 potential transmembrane domains. Mechanical activation of the channel results in influx of sodium and calcium, which can lead to the propagation of electrical signals and initiate intracellular secondary messenger pathways. Vertebrates have two Piezo genes, PIEZO1 and PIEZO2, and the resulting proteins share ∼50% identity at the amino acid level. It is likely that they evolved to take on specialized roles in the particular tissues in which they are expressed: PIEZO1 is expressed mainly in non-neuronal cells, whereas PIEZO2 is expressed in sensory neurons and in some specialized mechanosensory structures."], "t": []}], "preferred_name": "Piezo type mechanosensitive ion channel components", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22906:SF43", "l": "PROPERDIN", "d": [], "t": []}], "preferred_name": "PROPERDIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46046", "l": "PEPTIDYLPROLYL ISOMERASE", "d": [], "t": []}], "preferred_name": "PEPTIDYLPROLYL ISOMERASE", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22406", "l": "NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM", "d": [], "t": []}], "preferred_name": "NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR28457:SF3", "l": "CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1", "d": [], "t": []}], "preferred_name": "CILIARY-ASSOCIATED CALCIUM-BINDING COILED-COIL PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46470", "l": "N-ACYLNEURAMINATE-9-PHOSPHATASE", "d": [], "t": []}], "preferred_name": "N-ACYLNEURAMINATE-9-PHOSPHATASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10628:SF25", "l": "SIALIDASE-1", "d": [], "t": []}], "preferred_name": "SIALIDASE-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15818", "l": "G PATCH AND KOW-CONTAINING", "d": [], "t": []}], "preferred_name": "G PATCH AND KOW-CONTAINING", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14428", "l": "NUCLEOLAR COMPLEX PROTEIN 3", "d": [], "t": []}], "preferred_name": "NUCLEOLAR COMPLEX PROTEIN 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22791", "l": "RING-TYPE DOMAIN-CONTAINING PROTEIN", "d": [], "t": []}], "preferred_name": "RING-TYPE DOMAIN-CONTAINING PROTEIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24023:SF845", "l": "COLLAGEN ALPHA-1(XXII) CHAIN", "d": [], "t": []}], "preferred_name": "COLLAGEN ALPHA-1(XXII) CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10267:SF0", "l": "DNA POLYMERASE SUBUNIT GAMMA-1", "d": [], "t": []}], "preferred_name": "DNA POLYMERASE SUBUNIT GAMMA-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12821", "l": "BYSTIN", "d": [], "t": []}], "preferred_name": "BYSTIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13233:SF0", "l": "MICROSPHERULE PROTEIN 1", "d": [], "t": []}], "preferred_name": "MICROSPHERULE PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10210", "l": "RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER", "d": [], "t": []}], "preferred_name": "RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10689", "l": "MICROSOMAL GLUTATHIONE S-TRANSFERASE 1", "d": [], "t": []}], "preferred_name": "MICROSOMAL GLUTATHIONE S-TRANSFERASE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21013", "l": "ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR", "d": [], "t": []}], "preferred_name": "ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12113:SF12", "l": "DICKKOPF-RELATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "DICKKOPF-RELATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14928:SF6", "l": "ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7B", "d": [], "t": []}], "preferred_name": "ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 7B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46691", "l": "HIGH MOBILITY GROUP B PROTEIN 9", "d": [], "t": []}], "preferred_name": "HIGH MOBILITY GROUP B PROTEIN 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10663", "l": "GUANYL-NUCLEOTIDE EXCHANGE FACTOR", "d": [], "t": []}], "preferred_name": "GUANYL-NUCLEOTIDE EXCHANGE FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24340:SF28", "l": "HOMEOBOX PROTEIN NKX-2.5", "d": [], "t": []}], "preferred_name": "HOMEOBOX PROTEIN NKX-2.5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3441", "l": "Prostaglandin-endoperoxide synthase family", "d": ["Prostaglandin-endoperoxide synthases catalyze the committed step in prostaglandin synthesis and act both as a cyclooxygenases and peroxidases."], "t": []}], "preferred_name": "Prostaglandin-endoperoxide synthase family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15564:SF7", "l": "BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 1", "d": [], "t": []}], "preferred_name": "BMP_RETINOIC ACID-INDUCIBLE NEURAL-SPECIFIC PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11073", "l": "CALRETICULIN AND CALNEXIN", "d": [], "t": []}], "preferred_name": "CALRETICULIN AND CALNEXIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR34491:SF144", "l": "CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1", "d": [], "t": []}], "preferred_name": "CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24235:SF20", "l": "NEUROPEPTIDE Y RECEPTOR TYPE 2", "d": [], "t": []}], "preferred_name": "NEUROPEPTIDE Y RECEPTOR TYPE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR35971:SF4", "l": "OBSCURIN", "d": [], "t": []}], "preferred_name": "OBSCURIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24039:SF22", "l": "FIBRILLIN-1", "d": [], "t": []}], "preferred_name": "FIBRILLIN-1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43636:SF2", "l": "ELONGATION FACTOR G, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ELONGATION FACTOR G, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12839:SF7", "l": "REGULATOR OF NONSENSE TRANSCRIPTS 2", "d": [], "t": []}], "preferred_name": "REGULATOR OF NONSENSE TRANSCRIPTS 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15337:SF1", "l": "ANTERIOR GRADIENT PROTEIN 2 HOMOLOG", "d": [], "t": []}], "preferred_name": "ANTERIOR GRADIENT PROTEIN 2 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22911:SF6", "l": "SOLUTE CARRIER FAMILY 35 MEMBER G1", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 35 MEMBER G1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45618:SF8", "l": "MITOCHONDRIAL UNCOUPLING PROTEIN 4", "d": [], "t": []}], "preferred_name": "MITOCHONDRIAL UNCOUPLING PROTEIN 4", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11736:SF163", "l": "NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 3 HOMOLOG", "d": [], "t": []}], "preferred_name": "NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 3 HOMOLOG", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16983:SF13", "l": "LYMPHOCYTE ANTIGEN 6E", "d": [], "t": []}], "preferred_name": "LYMPHOCYTE ANTIGEN 6E", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46276", "l": "E3 UBIQUITIN-PROTEIN LIGASE UBR5", "d": [], "t": []}], "preferred_name": "E3 UBIQUITIN-PROTEIN LIGASE UBR5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR45998:SF2", "l": "SERINE_THREONINE-PROTEIN KINASE 16", "d": [], "t": []}], "preferred_name": "SERINE_THREONINE-PROTEIN KINASE 16", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR48002:SF53", "l": "OLFACTORY RECEPTOR 4C15", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 4C15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11740:SF0", "l": "CASEIN KINASE II SUBUNIT BETA", "d": [], "t": []}], "preferred_name": "CASEIN KINASE II SUBUNIT BETA", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10728:SF13", "l": "CYTOSOLIC PHOSPHOLIPASE A2", "d": [], "t": []}], "preferred_name": "CYTOSOLIC PHOSPHOLIPASE A2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10901:SF3", "l": "LEIOMODIN-3", "d": [], "t": []}], "preferred_name": "LEIOMODIN-3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR15417:SF2", "l": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B", "d": [], "t": []}], "preferred_name": "PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 1B", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:3649", "l": "Branched chain alpha-keto acid dehydrogenase complex subunits", "d": ["Leucine, isoleucine, and valine are collectively known as branched chain amino acids (BCAAs). Muscular proteins are dominantly built with BCAAs, which make up 20% to 25% of all amino acids in dietary proteins and play primary roles in muscular function. <a href='https://genenames.org/data/genegroup/#!/group/3518'>BCAT aminotransferases</a> transfer the amino group of BCAAs to 2-ketoglutarate, which results in corresponding branched chain 2-keto acids (BCKAs) and glutamate. BCKDH performs an oxidative decarboxylation of BCKAs, which produces their coenzyme A-conjugates and NADH."], "t": []}], "preferred_name": "Branched chain alpha-keto acid dehydrogenase complex subunits", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR21328", "l": "POLY  ADP-RIBOSE  POLYMERASE FAMILY, MEMBER  PARP", "d": [], "t": []}], "preferred_name": "POLY  ADP-RIBOSE  POLYMERASE FAMILY, MEMBER  PARP", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23340:SF2", "l": "SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 2", "d": [], "t": []}], "preferred_name": "SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24225:SF49", "l": "CHEMERIN-LIKE RECEPTOR 1", "d": [], "t": []}], "preferred_name": "CHEMERIN-LIKE RECEPTOR 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24058:SF53", "l": "HOMEODOMAIN-INTERACTING PROTEIN KINASE 2", "d": [], "t": []}], "preferred_name": "HOMEODOMAIN-INTERACTING PROTEIN KINASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11647:SF56", "l": "DIHYDROPYRIMIDINASE-RELATED PROTEIN 2", "d": [], "t": []}], "preferred_name": "DIHYDROPYRIMIDINASE-RELATED PROTEIN 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11213:SF5", "l": "VIP PEPTIDES", "d": [], "t": []}], "preferred_name": "VIP PEPTIDES", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11639:SF146", "l": "PROTEIN S100-A7A", "d": [], "t": []}], "preferred_name": "PROTEIN S100-A7A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR47595", "l": "HEAT SHOCK 70 KDA PROTEIN 14", "d": [], "t": []}], "preferred_name": "HEAT SHOCK 70 KDA PROTEIN 14", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24023:SF866", "l": "COLLAGEN ALPHA-3(IX) CHAIN", "d": [], "t": []}], "preferred_name": "COLLAGEN ALPHA-3(IX) CHAIN", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR43605:SF8", "l": "ACYL-COENZYME A SYNTHETASE ACSM4, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "ACYL-COENZYME A SYNTHETASE ACSM4, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19256:SF44", "l": "T CELL RECEPTOR GAMMA VARIABLE 9", "d": [], "t": []}], "preferred_name": "T CELL RECEPTOR GAMMA VARIABLE 9", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24064:SF34", "l": "SOLUTE CARRIER FAMILY 22 MEMBER 20", "d": [], "t": []}], "preferred_name": "SOLUTE CARRIER FAMILY 22 MEMBER 20", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26452:SF165", "l": "OLFACTORY RECEPTOR 10W1", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 10W1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR14463", "l": "LIPASE MATURATION FACTOR", "d": [], "t": []}], "preferred_name": "LIPASE MATURATION FACTOR", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24404:SF1", "l": "ZINC FINGER PROTEIN 821", "d": [], "t": []}], "preferred_name": "ZINC FINGER PROTEIN 821", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22811:SF41", "l": "TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 5", "d": [], "t": []}], "preferred_name": "TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 5", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24232:SF25", "l": "P2Y PURINOCEPTOR 8", "d": [], "t": []}], "preferred_name": "P2Y PURINOCEPTOR 8", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR46097", "l": "G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP", "d": [], "t": []}], "preferred_name": "G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10912:SF4", "l": "ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE 2", "d": [], "t": []}], "preferred_name": "ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE 2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13602:SF2", "l": "UPF0488 PROTEIN C8ORF33", "d": [], "t": []}], "preferred_name": "UPF0488 PROTEIN C8ORF33", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24068:SF393", "l": "UBIQUITIN-CONJUGATING ENZYME E2 S", "d": [], "t": []}], "preferred_name": "UBIQUITIN-CONJUGATING ENZYME E2 S", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1257", "l": "Jun transcription factor family", "d": [], "t": []}], "preferred_name": "Jun transcription factor family", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR16001:SF6", "l": "ECTO-NOX DISULFIDE-THIOL EXCHANGER 1", "d": [], "t": []}], "preferred_name": "ECTO-NOX DISULFIDE-THIOL EXCHANGER 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11751", "l": "ALANINE AMINOTRANSFERASE", "d": [], "t": []}], "preferred_name": "ALANINE AMINOTRANSFERASE", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "HGNC.FAMILY:1487", "l": "CAP and C-type lectin domain containing", "d": [], "t": []}], "preferred_name": "CAP and C-type lectin domain containing", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR13720:SF22", "l": "ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1", "d": [], "t": []}], "preferred_name": "ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10110:SF59", "l": "SODIUM_HYDROGEN EXCHANGER 1", "d": [], "t": []}], "preferred_name": "SODIUM_HYDROGEN EXCHANGER 1", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12317:SF36", "l": "2-ACYLGLYCEROL O-ACYLTRANSFERASE 3", "d": [], "t": []}], "preferred_name": "2-ACYLGLYCEROL O-ACYLTRANSFERASE 3", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR19944:SF50", "l": "HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM ALPHA CHAIN", "d": [], "t": []}], "preferred_name": "HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DM ALPHA CHAIN", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10755", "l": "COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL", "d": [], "t": []}], "preferred_name": "COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24024", "l": "PULMONARY SURFACTANT-ASSOCIATED PROTEIN A", "d": [], "t": []}], "preferred_name": "PULMONARY SURFACTANT-ASSOCIATED PROTEIN A", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24168:SF19", "l": "KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1", "d": [], "t": []}], "preferred_name": "KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR22624", "l": "CYSTEINE PROTEASE ATG4", "d": [], "t": []}], "preferred_name": "CYSTEINE PROTEASE ATG4", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR24103:SF312", "l": "TRIPARTITE MOTIF-CONTAINING PROTEIN 75", "d": [], "t": []}], "preferred_name": "TRIPARTITE MOTIF-CONTAINING PROTEIN 75", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR26452:SF135", "l": "OLFACTORY RECEPTOR 5H15", "d": [], "t": []}], "preferred_name": "OLFACTORY RECEPTOR 5H15", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR10489:SF916", "l": "C-X-C CHEMOKINE RECEPTOR TYPE 1", "d": [], "t": []}], "preferred_name": "C-X-C CHEMOKINE RECEPTOR TYPE 1", "taxa": []}
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{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR12413:SF2", "l": "DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED", "d": [], "t": []}], "preferred_name": "DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE-RELATED", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR23239:SF155", "l": "KERATIN, TYPE I CUTICULAR HA2", "d": [], "t": []}], "preferred_name": "KERATIN, TYPE I CUTICULAR HA2", "taxa": []}
{"type": "biolink:GeneFamily", "ic": null, "identifiers": [{"i": "PANTHER.FAMILY:PTHR11058:SF9", "l": "NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3", "d": [], "t": []}], "preferred_name": "NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 3", "taxa": []}