name: Formation of the Spliceosomal B complex (Mus musculus)


name: carbovir + IMP => carbovir monophosphate + inosine (Xenopus tropicalis)


name: MCOLN1 transports Fe2+ from endosome lumen to cytosol (Danio rerio)


name: Integrin alpha5beta1 binds FN1 dimer (Sus scrofa)


name: Caspase-1 active tetramer formation (Xenopus tropicalis)


name: XIAP dissociates from ub-TLE (Rattus norvegicus)


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 22-hydroxy-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: NUBPL binds 4Fe-4S (Dictyostelium discoideum)


name: Release of 40S and 60S subunits from the 80S ribosome  (Canis familiaris)


name: a very long-chain fatty acyl-CoA + H2O => a very long-chain fatty acid + CoA + H(+)


name: PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Canis familiaris)


name: Association of procollagen type XXIV (Xenopus tropicalis)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Sus scrofa)


name: (E)-4-hydroxynon-2-enoate + H2O2 + H(+) => (E)-4-hydroxynon-2-enal + O2 + H2O


name: a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + S-adenosyl-L-homocysteine + H(+)


name: NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Caenorhabditis elegans)


name: 3-(2,4-dioxopentyl)-2,3,6,8,9-pentahydroxy-1-oxo-1,2,3,4-tetrahydroanthracene-2-carboxyl-[ACP] => 2-acetyl-3,4a,8,10,11,12a-hexahydroxy-1,4,4a,5,12,12a-hexahydrotetracene-1,12-dione + holo-[ACP] + H(+)


name: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate


name: (2R,3S)-3-isopropylmalate(in) + sulfate(out) = (2R,3S)-3-isopropylmalate(out) + sulfate(in)


name: a 2,3-saturated acyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> a (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: (4R)-limonene + A + H2O => (4R)-perillyl alcohol + AH2


name: M1 muscarinic acetylcholine receptor binding


name: ATP2B1-4 transport cytosolic Ca2+ to extracellular region (Drosophila melanogaster)


name: Cdc45 associates with the pre-replicative complex at the origin (Bos taurus)


name: 3,6-dichloropyridine-2,5-diol + FADH2 + O2 <=> 6-chloro-3-hydroxypyridine-2,5-dione + FAD + chloride + H2O + 2 H(+)


name: Exocytosis of azurophil granule lumen proteins (Sus scrofa)


name: (S)-3-Hydroxyhexadecanoyl-CoA+NAD => 3-Oxopalmitoyl-CoA+NADH+H (Bos taurus)


name: ERK5 translocates to the nucleus (Sus scrofa)


name: indole-3-carbaldehyde + O2 + H2O = indole-3-carboxylate + H2O2 + H(+)


name: PXLP-K314-GPT transaminates L-Ala to form PYR (Danio rerio)


name: N(6)-(1-hydroxy-2-oxoethyl)-L-lysyl-[protein] + H2O => glycolate + L-lysyl-[protein] + H(+)


name: (8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: JMJD7 dimer hydroxlates a lysine residue of DRG2 (Mus musculus)


name: Slo3 Potassium Transport (Drosophila melanogaster)


name: succinate semialdehyde + methylamine + H2O2 => 4-(methylamino)butanoate + O2 + H2O


name: GCH1 reduces GTP to dihydroneopterin triphosphate (Dictyostelium discoideum)


name: Translation of NOTCH2NLA mRNA (Homo sapiens)


name: Increased Sympathetic Histamine Activity


name: ORC6 binds KPNA1 or KPNA6 (Rattus norvegicus)


name: RHOC activates endoplasmic reticulum effectors (Rattus norvegicus)


name: [phosphate](n) + ADP <=> [phosphate](n+1) + AMP


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Canis familiaris)


name: hexanoyl-CoA + FAD + H(+) <=> (2E)-hexenoyl-CoA + FADH2


name: L-cysteinylglycine + L-glutamate => glutathione + H2O


name: Removal of fibrillar collagen C-propeptides (Bos taurus)


name: D-arabinono-1,5-lactone + NADH + H(+) => D-arabinose + NAD(+)


name: D-sorbitol + NADP(+) = D-glucose + NADPH + H(+)


name: RNASEL cleaves cellular ssRNA (Mus musculus)


name: NOSTRIN mediated translocation of eNOS from plasma membrane (Bos taurus)


name: deoxycholoyl-CoA + NAD(+) <=> 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NADH + H(+)


name: plastoquinol-9 + 9,9',15-tri-cis-zeta-carotene => plastoquinone-9 + 15,9'-di-cis-phytofluene


name: N(alpha)-methyl-L-tryptophan + S-adenosyl-L-methionine = N(alpha),N(alpha)-dimethyl-L-tryptophan + S-adenosyl-L-homocysteine + H(+)


name: mycophenolate + UDP-alpha-D-glucuronate <=> mycophenolate 7-O-beta-D-glucuronide + UDP + H(+)


name: 2-dehydro-3-deoxy-D-gluconate + H2O => D-mannonate


name: narbomycin + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 4 H(+) <=> novapikromycin + 4 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: p-Y701-STAT1 binds p-Y705-STAT3 (Caenorhabditis elegans)


name: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized 2[4Fe-4S]-[ferredoxin] => 6-hydroxynicotinate + reduced 2[4Fe-4S]-[ferredoxin] + 2 H(+)


name: MHC class II antigen processing (Homo sapiens)


name: indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] + CoA <=> (indol-3-yl)acetyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + CO2 + H(+)


name: 3-aminoavenalumate + nitrite + ATP = 3-diazoavenalumate + AMP + diphosphate + H2O


name: benzothialdehyde + H2O2 => benzylthiol + O2


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Danio rerio)


name: peniprequinolone + A <=> yaequinolone E + AH2


name: DAG1(30-653) and DAG1(654-895) translocate to the Golgi (Mus musculus)


name: MDH1 reduces OA (Drosophila melanogaster)


name: ARL2:GTP:ARL2BP translocates from cytosol to the mitochondrial matrix (Rattus norvegicus)


name: 2xTPK1:Mg2+ phosphorylates THMN (Rattus norvegicus)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO1 (Rattus norvegicus)


name: NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Bos taurus)


name: [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine => [protein]-L-isoaspartate + S-adenosyl-L-methionine


name: poly(hydroxyalkanoate) biosynthetic process from fatty acid


name: histone H4K8 deacetylase activity, hydrolytic mechanism


name: aristolene + diphosphate => (2E,6E)-farnesyl diphosphate


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate


name: Activated MAPKs phosphorylate MAP2K1 (Homo sapiens)


name: (2S)-2-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E)-2-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]


name: Autocatalytic phosphorylation of FGFR1b (Homo sapiens)


name: negative regulation of PMK1-MAPK signal transduction pathway


name: stimulation of antibacterial peptide biosynthetic process


name: activation of nitrogen cycle metabolic process


name: ASPA deacetylates NAASP to acetate and L-aspartate (Xenopus tropicalis)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Plasmodium falciparum)


name: DDAH1 hydrolyses ADMA to DMA and L-Cit (Sus scrofa)


name: ASAP1 stimulates GTPase activity of ARF4 (Gallus gallus)


name: RAC1 and CDC42 activate PAK1 (Canis familiaris)


name: L-phenylalanine(out) + L-serine(in) => L-phenylalanine(in) + L-serine(out)


name: Pb(2+)(in) + ATP + H2O => Pb(2+)(out) + ADP + phosphate + H(+)


name: 4-hydroxybutanoate + NAD(+) <=> succinate semialdehyde + NADH + H(+)


name: trihexanoylglycerol + H2O => 2,3-dihexanoyl-sn-glycerol + hexanoate + H(+)


name: dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + acetyl-CoA => dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + CoA + H(+)


name: thymine + A + H2O = 5-methylbarbiturate + AH2 + H(+)


name: CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Drosophila melanogaster)


name: Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Sus scrofa)


name: spermidine(out) + n H(+)(in) => spermidine(in) + n H(+)(out)


name: regulation of epidermal growth factor receptor signaling pathway involved in heart process


name: nonaprenyl pyrophosphate synthetase activity


name: AGRN binds Integrins alphaVbeta1 (Other beta1-containing integrins) (Homo sapiens)


name: L-lysine + NADP(+) + H2O <=> (S)-2-amino-6-oxohexanoate + NH4(+) + NADPH + H(+)


name: 'de novo' NAD biosynthetic process from tryptophan


name: Activation of Ca permeable AMPA receptors (Gallus gallus)


name: HHAT palmitoylates Hh N-terminal fragment (Sus scrofa)


name: guanidinoethyl methyl phosphate + ATP => N'-phosphoguanidinoethyl methylphosphate + ADP + H(+)


name: S-acetylphosphopantotheine + holo-[citrate lyase ACP] => acetyl-[citrate lyase ACP] + (R)-4'-phosphopantetheine


name: (d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Sus scrofa)


name: DHRS7B reduces GO3P to HXDG3P (Caenorhabditis elegans)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man7GlcNAc2 to produce Man5GlcNAc2 (Bos taurus)


name: PLC gamma 2-mediated PIP2 hydrolysis (Mus musculus)


name: campesine D + reduced [NADPH--hemoprotein reductase] + O2 = campesine G + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: 17-(4-hydroxyphenyl)heptadecanoyl-5'-AMP + holo-[(phenol)carboxyphthiodiolenone synthase] = 17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + H(+)


name: G-beta:G-gamma inhibits Adenylate cyclase (Danio rerio)


name: L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine


name: activation of (Na+ + K+)-activated ATPase activity


name: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose => an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: sucrose + H2O => glucose + fructose (Mus musculus)


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Dictyostelium discoideum)


name: a pseudouridine in RNA => a uridine in RNA


name: Ubiquitination of p130 (RBL2) by SCF (Skp2) (Dictyostelium discoideum)


name: glutathione(out) + ADP + phosphate + H(+) => glutathione(in) + ATP + H2O


name: SCF(SKP2) polyubiquitinates RUNX2 (Caenorhabditis elegans)


name: The UDP/CysLT (P2Y17) receptor can bind UTP (Mus musculus)


name: PIAS1 SUMOylates DDX5 with SUMO2 (Bos taurus)


name: CSKMT methylates Citrate Synthase (Bos taurus)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Xenopus tropicalis)


name: cAMP degradation by Phosphodiesterases (Danio rerio)


name: (R)-3-phenyllactate + FAD + H(+) <=> 3-phenylpyruvate + FADH2


name: (1->3)-alpha-D-glucosyl-[(1->6)-alpha-D-glucosyl](n) + D-fructose => [(1->6)-alpha-D-glucosyl](n) + sucrose


name: a (2S)-2-hydroxycarboxylate + O2 <=> a 2-oxocarboxylate + H2O2


name: LINC01139 facilitates PTK6 autophosphorylation (Mus musculus)


name: Collagen type VII degradation by MMP1,2,3 (Rattus norvegicus)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 = 17-hydroperoxy-(7Z,10Z,13Z,15E,19Z)-docosapentaenoate


name: D-alanine(in) + Na(+)(in) = D-alanine(out) + Na(+)(out)


name: 1-O-heptadecylglycerone 3-phosphate + hexadecanoate + H(+) => heptadecan-1-ol + 1-hexadecanoylglycerone 3-phosphate


name: ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Dictyostelium discoideum)


name: 1-beta-D-galactosyl-2,3-didodecanoyl-sn-glycerol + H2O = 1-beta-D-galactosyl-dodecanoyl-sn-glycerol + dodecanoate + H(+)


name: Arachidonate is epoxidated to 8,9-EET by CYP(5) (Mus musculus)


name: 2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H2O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + NH4(+) + CO2


name: RB1 recruits APC/C:Cdh1 complex to SKP2 (Bos taurus)


name: NFE2L2 binds CREBBP,EP300 (Caenorhabditis elegans)


name: Autophosphorylation of PDGF alpha receptors (Gallus gallus)


name: glutathione(in) + ADP + phosphate + H(+) => glutathione(out) + ATP + H2O


name: TFAP2C translocates to the nucleus (Xenopus tropicalis)


name: BTK binds BTK inhibitors (Canis familiaris)


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Rattus norvegicus)


name: 1-acyl LPG is acylated to PG by CRLS1 (IM) (Mus musculus)


name: NMT1/2 transfer MYS to GNAT1 (Sus scrofa)


name: 17-hydroperoxy-(7Z,10Z,13Z,15E,19Z)-docosapentaenoate => (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2


name: an (R)-2-alkyl-3-oxoalkanoate + NADPH + H(+) => a (2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP(+)


name: GLB1 hydrolyses linker chain(2) (Homo sapiens)


name: CYP11B2 18-hydroxylates CORST to 18HCORST (Canis familiaris)


name: ABCA7:Apo1A-mediated phospholipid efflux (Homo sapiens)


name: Ubiquitinated Cdc6 is degraded by the proteasome (Drosophila melanogaster)


name: Activated FGFR3 phosphorylates PLCG1 (Mus musculus)


name: 6-chloro-D-tryptophan + FAD + 2 H2O => D-tryptophan + FADH2 + chloride + O2


name: PGAM dimers isomerise 2PG to 3PG (Sus scrofa)


name: Addition of the third nucleotide on the nascent transcript (Dictyostelium discoideum)


name: AcK-NFE2L2 binds the ATF4 gene (Homo sapiens)


name: mitochondrial protein-transporting ATPase activity


name: 2 cob(II)inamide + reduced [electron-transfer flavoprotein] + 2 ATP <=> 2 adenosylcob(III)inamide + 2 triphosphate + oxidized [electron-transfer flavoprotein] + 3 H(+)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Schizosaccharomyces pombe)


name: RAB43:GTP binds USP8NL (Drosophila melanogaster)


name: an (11Z)-eicosenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a (8Z,11Z)-eicosadienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: 2,2-dihydroxyspheroidene + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => 2-hydroxyspheroidene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: pseudouridine(13) in tRNA => uridine(13) in tRNA


name: L-glutamine(out) + ATP + H2O <=> L-glutamine(in) + ADP + phosphate + H(+)


name: 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + H2O => 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + phosphate + H(+)


name: PAAP-A proteolyzes IGF:IGFBP4 (Gallus gallus)


name: WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Bos taurus)


name: menaquinol-8 + NADP(+) => menaquinone-8 + NADPH + H(+)


name: 1-O-22-methyltricosyl (9Z)-octadecenoate + CoA => 22-methyltricosan-1-ol + (9Z)-octadecenoyl-CoA


name: phosphorylated HSL dimer + FABP4 -> phosphorylated HSL dimer:FABP4 complex (Homo sapiens)


name: citrate(in) + 3 H(+)(in) <=> citrate(out) + 3 H(+)(out)


name: N(2)-succinyl-L-citrulline + phosphate + H(+) => N(2)-succinyl-L-ornithine + carbamoyl phosphate


name: [LarE protein]-L-cysteine + pyridinium-3-carboxylate-5-thiocarboxylate mononucleotide + ATP = pyridinium-3,5-bisthiocarboxylate mononucleotide + [LarE protein]-dehydroalanine + AMP + diphosphate + H(+)


name: 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H2O <=> sn-glycero-3-phospho-L-serine + hexadecanoate + H(+)


name: BIL dissociates from GSTA1, FABP1 (Danio rerio)


name: a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acyl-[ACP] => a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + holo-[ACP]


name: NTPDase3 hydrolyzes nucleoside diphosphates (Rattus norvegicus)


name: 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde => 2-oxepin-2(3H)-ylideneacetyl-CoA + H2O


name: PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Bos taurus)


name: IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Canis familiaris)


name: ESYT1:ESYT2:ESYT3 transport GPL from plasma membrane to ER membrane (Gallus gallus)


name: 5-aminomethyl-2-thiouridine(34) in tRNA + glyoxylate + AH2 => 5-carboxymethylaminomethyl-2-thiouridine(34) in tRNA + A + H2O


name: (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + malonyl-CoA + H(+) => 3-oxo-(17Z,20Z,23Z,26Z,29Z)-dotriacontapentaenoyl-CoA + CO2 + CoA


name: 6-deoxy-6-sulfo-D-glucono-1,5-lactone + H2O = 6-deoxy-6-sulfo-D-gluconate + H(+)


name: S-adenosyl-L-methionine + H(+) <=> S-adenosyl 3-(methylsulfanyl)propylamine + CO2


name: Expression of STAT5 upregulated genes (Homo sapiens)


name: 1-hydroxy-all-trans-1,2-dihydro-neurosporene + A => demethylspheroidene + AH2


name: (4-hydroxyphenyl)acetaldehyde + H2O2 + NH4(+) => tyramine + O2 + H2O


name: 11,12-EET is hydrolysed to 11,12-DHET by EPHX2 (Danio rerio)


name: Activation of GIRK/Kir3 Channels (Sus scrofa)


name: UGT1A3 lactonizes ATV to ATVL (Homo sapiens)


name: KCTD1 binds TFAP2 homo- and heterodimers (Bos taurus)


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Mus musculus)


name: CDP-DAG is converted to PGP by PGS1 (Homo sapiens)


name: a ganglioside GQ1c + CMP-N-acetyl-beta-neuraminate <=> a ganglioside GP1c + CMP + H(+)


name: daunorubicin + NADPH + H(+) <=> 13-dihydrodaunorubicin + NADP(+)


name: SLC31A1 transports Cu1+ from extracellular region to cytosol (Drosophila melanogaster)


name: Endocytosis of TRAM (TICAM2) (Bos taurus)


name: Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Dictyostelium discoideum)


name: 3-oxo-(11Z)-eicosenoyl-CoA + CoA => (9Z)-octadecenoyl-CoA + acetyl-CoA


name: IFN alpha/beta binds to IFNAR2 (Rattus norvegicus)


name: JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)


name: dGMP(out) + NAD(+)(in) => dGMP(in) + NAD(+)(out)


name: RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)


name: N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioyl-D-alanine + H2O = N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioate + D-alanine


name: Decreased Smooth Muscle Brain Derived Neurotropic Activity


name: an aldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O <=> a carboxylate + 2 reduced [2Fe-2S]-[ferredoxin] + 3 H(+)


name: CUBN:AMN binds CBLIF:RCbl (Drosophila melanogaster)


name: Arachidonate is oxidised to PGG2 by PTGS2 (Sus scrofa)


name: Transport of MHC II:Ii complex to plasma membrane (Homo sapiens)


name: regulation of membrane associated actin binding


name: SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Gallus gallus)


name: C-ter TLR7 dimer binds SARS-CoV-2 GU-rich ssRNA (Homo sapiens)


name: octyl benzoate + CoA => octan-1-ol + benzoyl-CoA


name: benzene + NADH + O2 + H(+) => cis-1,2-dihydrobenzene-1,2-diol + NAD(+)


name: HNF1B binds the IRX2 gene (Homo sapiens)


name: 2-O-(alpha-D-glucopyranosyl)glycerol + phosphate => alpha-D-glucose 1-phosphate + glycerol


name: Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)


name: 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O <=> 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoate + H(+)


name: Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)


name: 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: 17alpha-estradiol + UDP-alpha-D-glucuronate = 17alpha-estradiol 17-O-(beta-D-glucuronate) + UDP + H(+)


name: CSNK2-mediated phosphorylation of DVL (Danio rerio)


name: a 2'-deoxyribonucleoside 5'-phosphate + dGTP <=> a 2'-deoxyribonucleoside 5'-diphosphate + dGDP


name: PPARGC1A  gene expression is stimulated by EBF2 (Homo sapiens)


name: CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly (Saccharomyces cerevisiae)


name: Exocytosis of secretory granule membrane proteins (Plasmodium falciparum)


name: (11Z)-eicosenoate + ATP + CoA <=> (11Z)-eicosenoyl-CoA + AMP + diphosphate


name: FOLR2 transports FOLA from extracellular region to cytosol (Mus musculus)


name: Platelet Amyloid Precursor Protein Pathway


name: L-isoleucine(in) + L-phenylalanine(out) => L-isoleucine(out) + L-phenylalanine(in)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)


name: L3MBTL1 binds TP53 monomethylated on K382 (Sus scrofa)


name: ethylamine + glyoxylate + H2O2 => N-ethylglycine + O2 + H2O


name: phosphonoacetate + H2O = acetate + phosphate + H(+)


name: Factor H binds to membrane-associated C3b (Canis familiaris)


name: GSK3 phosphorylates p-GLI3 (Drosophila melanogaster)


name: NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)


name: (6S)-3,3-dimethylpiperidine-2,6-dicarboxylate + NAD(+) => (2S)-5,5-dimethyl-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADH + 2 H(+)


name: Importin-8 imports AGO2:miRNA into the nucleus (Gallus gallus)


name: diethyl 2-methyl-3-oxosuccinate reductase activity


name: Activated FGFR3:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Gallus gallus)


name: Peroxynitrite enters the bacterium (Homo sapiens)


name: MAP2K1 phosphorylates MAPK3 (Homo sapiens)


name: 1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate <=> 1,3-di-(10Z-heptadecenoyl)-glycerol + 9-(10Z-heptadecenoyloxy)-octadecanoate


name: N(6)-[(S)-lactoyl]-L-lysyl-[protein] + H2O = (S)-lactate + L-lysyl-[protein]


name: ZFP36 (TTP) recruits RNA degradation activities (Drosophila melanogaster)


name: zealexin A1 + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+) => (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + reduced [NADPH--hemoprotein reductase] + O2


name: holo-[compactin nonaketide synthase] + 9 malonyl-CoA + 11 NADPH + 20 H(+) = dihydro-ML-236C-[compactin nonaketide synthase] + 9 CO2 + 11 NADP(+) + 9 CoA + 6 H2O


name: GPER:Heterotrimeric G-protein Gs binds ESTG (Homo sapiens)


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Rattus norvegicus)


name: 5-hydroxypentan-2-amine + NAD(+) + H2O <=> 5-hydroxypentan-2-one + NH4(+) + NADH + H(+)


name: coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2


name: coproporphyrinogen III oxidase (coproporphyrin-forming)


name: 3alpha-hydroxy-5alpha-androstan-11,17-dione + NADPH + H(+) => 3alpha,17beta-dihydroxy-5alpha-androstan-11-one + NADP(+)


name: L-glutaminyl-[protein] + dopamine => 5-dopaminyl-L-glutamyl-[protein] + NH4(+)


name: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnose + H2O <=> 5-dehydro-4-deoxy-D-glucuronate + L-rhamnopyranose


name: 4-methylphenol + NAD(+) + H2O => toluene + NADH + O2 + H(+)


name: 5-phospho-alpha-D-ribose 1-diphosphate + 4-hydroxybenzoate + H(+) <=> 4-(beta-D-ribofuranosyl)phenol 5'-phosphate + CO2 + diphosphate


name: RABGGTA binds RABGGTB (Saccharomyces cerevisiae)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine => (9Z-octadecenoyl)-sn-glycero-3-phosphocholine + sn-glycero-3-phosphoethanolamine


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Saccharomyces cerevisiae)


name: (Z)-phenyl-N-(sulfonatooxy)methanimidothioate = phenylacetonitrile + sulfur + sulfate


name: aspartic protease activity involved in amyloid precursor protein breakdown


name: kallikrein:kininogen:cell surface receptor:factor XII -> kallikrein:kininogen:cell surface receptor + factor XIIa (kallikrein catalyst) (Sus scrofa)


name: alpha-D-glucose 6-phosphate + H2O = alpha-D-glucose + phosphate


name: RIPK3 binds STUB1 (Plasmodium falciparum)


name: positive regulation of caa3-type cytochrome c oxidase


name: (20S)-protopanaxatriol + UDP-alpha-D-glucose = (20S)-ginsenoside Rh1 + UDP + H(+)


name: Transport of the Mature Intronless Transcript Derived Histone mRNA:TAP:Aly/Ref Complex through the NPC (Sus scrofa)


name: guanosine(26)/guanosine(27) in tRNA + 4 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26)/N(2)-dimethylguanosine(27) in tRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)


name: Caspase-mediated cleavage of Lamin B1 (Xenopus tropicalis)


name: phosphorylation of 2'-Deoxythymidine to dTMP (Caenorhabditis elegans)


name: NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Canis familiaris)


name: nicotinate + S-adenosyl-L-methionine = methyl nicotinate + S-adenosyl-L-homocysteine


name: (1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) <=> catechol + NADPH + H(+)


name: 3-phenylpropanoate + NADH + O2 + H(+) => 3-(cis-5,6-dihydroxycyclohexa-1,3-dien-1-yl)propanoate + NAD(+)


name: beta-estradiol + PAPS => beta-estradiol 3-sulfate + PAP (Bos taurus)


name: SLC7A5:SLC3A2 transports neutral amino acids from extracellular region to cytosol (Rattus norvegicus)


name: acacetin + S-adenosyl-L-methionine <=> apigenin 4',7-dimethyl ether + S-adenosyl-L-homocysteine


name: Activated FGFR1 phosphorylates FRS3 (Bos taurus)


name: oxidoreductase activity, reducing metal ions, NAD or NADP as acceptor


name: L-tyrosine + ATP + NADPH + H(+) => L-tyrosinal + AMP + diphosphate + NADP(+)


name: 1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine <=> N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+)


name: Amination of uridine 5'-triphosphate (UTP) to form cytidine 5'-triphosphate (CTPS2) (Bos taurus)


name: 5S-HpETE is dehydrated to LTA4 by ALOX5 (Danio rerio)


name: an (E)-{[(2R,3S,4R,5R)-2,3,4,5-tetrahydroxyoxan-2-yl]methylidene}amine + H2O + H(+) => an aliphatic amine + 2-dehydro-D-glucose


name: N-methylpavine + S-adenosyl-L-homocysteine + H(+) => (+-)-pavine + S-adenosyl-L-methionine


name: Type B histone acetlytransferase complex acetylates histone H4 (Rattus norvegicus)


name: UDP-alpha-D-6-sulfoquinovose + a 1,2-diacyl-sn-glycerol = a 6-sulfo-alpha-D-quinovosyldiacylglycerol + UDP + H(+)


name: 2-acetyl-3,4a,8,10,11,12a-hexahydroxy-1,4,4a,5,12,12a-hexahydrotetracene-1,12-dione + S-adenosyl-L-methionine => TAN-1612 + S-adenosyl-L-homocysteine + H(+)


name: N-(beta-D-glucosyl)nicotinate + UDP => nicotinate + UDP-alpha-D-glucose


name: Translocation of tetracosahexaenoyl-CoA to peroxisomes (Mus musculus)


name: D-erythritol 1-phosphate + NADP(+) <=> D-erythrulose 1-phosphate + NADPH + H(+)


name: (2E,6E)-farnesyl phosphate + H2O <=> (2E,6E)-farnesol + phosphate


name: Formation of AT-AC B Complex (Rattus norvegicus)


name: LTA4H:Zn2+ hydrolyses 5S,6S-epoxy-18(S)-HEPE to 18(S)-RvE1 (Caenorhabditis elegans)


name: LONP1 degrades mitochondrial matrix proteins (Rattus norvegicus)


name: (S)-cis-N-methylcanadine + reduced [NADPH--hemoprotein reductase] + O2 = allocryptopine + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+) => 3-methylcatechol + NADH + H(+)


name: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2


name: ATPase-coupled phosphate ion transmembrane transporter activity


name: TAK1 is activated within the TAK1 complex (Sus scrofa)


name: inhibition of RNA nucleotidyltransferase (RNA-directed) activity


name: 2-acyl LPI is acylated to PI by MBOAT7 (Schizosaccharomyces pombe)


name: HTRA1 hydrolyzes ACAN (Aggrecan) (Rattus norvegicus)


name: ACSM2B-like proteins transform ST to ST-CoA (Homo sapiens)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (thioredoxin) (Bos taurus)


name: Translocation of PLC-gamma1 to PIP2 (Bos taurus)


name: 8-methyl-3-oxononanoyl-[ACP] + dihydroxyacetone phosphate <=> [4-(6-methylheptanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate + holo-[ACP] + H2O


name: eicosanoate + holo-[(phenol)carboxyphthiodiolenone synthase] + ATP => icosanoyl-[(phenol)carboxyphthiodiolenone synthase] + AMP + diphosphate


name: Arachidonate is oxidised to 5S-HpETE by ALOX5 (Mus musculus)


name: (11R)-dihydroartemisinic aldehyde + NADP(+) <=> (+)-artemisinic aldehyde + NADPH + H(+)


name: acetate(out) + 2 Na(+)(out) <=> acetate(in) + 2 Na(+)(in)


name: D-galactose + alpha-D-glucose 1-phosphate => beta-D-glucosyl-(1->4)-D-galactose + phosphate


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 FADH2 + 2 chloride + 2 O2 = (4,5-dichloro-1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 FAD + 4 H2O


name: rebaudioside B glucosyltransferase activity


name: (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 => 13,14-epoxy-(4Z,7Z,10Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: erythritol + ATP <=> D-erythritol 1-phosphate + ADP + H(+)


name: (E)-non-2-enal + NAD(+) + H2O <=> (E)-non-2-enoate + NADH + 2 H(+)


name: caffeine + a ubiquinone + H2O => 1,3,7-trimethylurate + a ubiquinol


name: Proton-coupled histidine and di-peptide cotransport (Homo sapiens)


name: a lyso-ornithine lipid + a fatty acyl-[ACP] <=> an N(2)-[(3R)-3-(acyloxy)acyl]-L-ornithine lipid + holo-[ACP]


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Mus musculus)


name: 19-oxo-androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 => estrone + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3 (Rattus norvegicus)


name: a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-glucosamine <=> beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-ceramide + UDP + H(+)


name: histidine => urocanate + NH4+ (Rattus norvegicus)


name: peptide mating pheromone maturation involved in positive regulation of conjugation with cellular fusion


name: L-glutamate + succinate => N-succinyl-L-glutamate + H2O


name: Activation of Rap1 by membrane-associated GEFs (Drosophila melanogaster)


name: [(1->2)-beta-D-mannosyl](n) + GDP-alpha-D-mannose => [(1->2)-beta-D-mannosyl](n+1) + GDP + H(+)


name: Internalization of ubiquitinated FLT3 (Xenopus tropicalis)


name: (+)-sesamin monocatechol + (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) => (+)-sesamin dicatechol + (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n)


name: Phosphorylation of WWTR1 (TAZ) by LATS1 (Danio rerio)


name: PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Homo sapiens)


name: 1-tetradecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O => 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + tetradecanoate + H(+)


name: notoamide E + NADPH + O2 + H(+) => notoamide D + NADP(+) + H2O


name: 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + ATP + CoA = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoyl-CoA + AMP + diphosphate


name: 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate (Gallus gallus)


name: NQO2:FAD dimer reduces quinones to hydroquinones (Xenopus tropicalis)


name: L-phenylalanine + CO2 + H2O => L-arogenate + H(+)


name: MME:Zn2+ (Neprilysin) hydrolyses AGT(25-33) (Angiotensin-(1-9)) to AGT(25-31) (Angiotensin-(1-7) (Xenopus tropicalis)


name: naphthalene-1,2,4,8-tetrol => juglone + H2O


name: Phosphorylated GPNMB recruits PTK6 and LRRK2 in the presence of LINC01139 (Homo sapiens)


name: The high affinity receptor complex binds to G-protein (Gallus gallus)


name: C2orf47:AFG3L2 binds the transit peptide of SMDT1 (Caenorhabditis elegans)


name: PtdIns(4,5)P2 binds WASP, N-WASP (Homo sapiens)


name: (2R)-2-hydroperoxyoctadecanoate + H(+) = heptadecanal + CO2 + H2O


name: Potassium voltage-gated channels close in reponse to PKA (Drosophila melanogaster)


name: RUNX1 binds PRC1 complexes (Xenopus tropicalis)


name: Dopamine is oxidised to noradrenaline (Drosophila melanogaster)


name: low-affinity sulfate:proton symporter activity


name: leukotriene B4 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-leukotriene B4 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PARP1 or PARP2 binds DDB2 at GG-NER site (Xenopus tropicalis)


name: amino acid catabolic process to alcohol via Ehrlich pathway


name: Receptor CCR7 binds CCL19 and 21 ligands (Rattus norvegicus)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Schizosaccharomyces pombe)


name: MIA3 binds procollagen VII (Homo sapiens)


name: an aldehyde + a quinone + H2O => a quinol + a carboxylate + H(+)


name: [N-acetyl-alpha-D-neuraminosyl-(2->8)](n+1) + CMP + H(+) => [N-acetyl-alpha-D-neuraminosyl-(2->8)](n) + CMP-N-acetyl-beta-neuraminate


name: octanal + 2 Fe(III)-[cytochrome c] + H2O => octanoate + 2 Fe(II)-[cytochrome c] + 3 H(+)


name: 5-hydroxy-3-[(3aS,4S,5R,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA => 3-[(3aS,4S,5R,7aS)-5-hydroxy-7a-methyl-1-oxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate


name: 7-carboxyadenylyl-7-carbaguanine + diphosphate => 7-carboxy-7-carbaguanine + ATP + H(+)


name: Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Homo sapiens)


name: SRD5A3 reduces polyprenal to dolichal (Canis familiaris)


name: IDH2 dimer decarboxylates isocitrate (Caenorhabditis elegans)


name: RANBP2 SUMOylates CDCA8 (Borealin) and PIAS3 SUMOylates AURKB (Aurora-B) (Rattus norvegicus)


name: LPPG:FO 2-phospho-L-lactate transferase activity


name: 1/3-PP-IP5 transports from the cytosol to the nucleus (Canis familiaris)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-1D-myo-inositol + H2O <=> 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-1D-myo-inositol + (9Z)-octadecenoate + H(+)


name: 3-deoxy-alpha-D-manno-oct-2-ulosonate + phosphate => 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + H2O


name: ATPase-coupled L-arginine transmembrane transporter activity


name: PCNA:POLD,POLE:RPA:RFC and FEN1 bind APEX1 (Canis familiaris)


name: N(6)-acetyl-N(6)-hydroxy-L-lysine + citrate + ATP = N(2)-citryl-N(6)-acetyl-N(6)-hydroxy-L-lysine + AMP + diphosphate + H(+)


name: ACOX2:FAD, ACOXL:FAD oxidise (2S)-pristanoyl-CoA to trans-2,3-dehydropristanoyl-CoA (Rattus norvegicus)


name: N-acetylation of serotonin (Mus musculus)


name: RhoGTPase GEF's recruited to DCC (Bos taurus)


name: Hemoglobin A binds O2, releasing H+ and CO2 (Bos taurus)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Dictyostelium discoideum)


name: N-methyl-L-alanine + NADP(+) + H2O = methylamine + pyruvate + NADPH + H(+)


name: pentanoyl-CoA + glyoxylate + H2O <=> 3-propylmalate + CoA + H(+)


name: GPR161 promotes cAMP production in a G alpha(s)-dependent manner (Danio rerio)


name: AXL autophosphorylates on Y779 and Y821 (Canis familiaris)


name: 4-deoxy-4-formamido-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + H2O = 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + formate


name: 2-methylpropanoyl phosphate + ADP => 2-methylpropanoate + ATP


name: voriconazole(in) + ATP + H2O = voriconazole(out) + ADP + phosphate + H(+)


name: TXNRD2 catalyzes the reduction of TXN2 by NADPH (Rattus norvegicus)


name: 6-geranylgeranyl-2-methylbenzene-1,4-diol + S-adenosyl-L-methionine = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)


name: all-trans-nonaprenyl diphosphate + 5 diphosphate => 5 isopentenyl diphosphate + (2E,6E,10E)-geranylgeranyl diphosphate


name: AcK-NFE2L2 and MAFK bind the GSTA1 gene (Homo sapiens)


name: crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasmin (Canis familiaris)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Mus musculus)


name: Relaxin 3 receptor 1 binds relaxin 3 (Mus musculus)


name: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine + H+ (Rattus norvegicus)


name: zeatin + UDP-alpha-D-xylose = O-beta-D-xylosylzeatin + UDP + H(+)


name: 2-hydroxyestrone + UDP-alpha-D-glucuronate => 2-hydroxyestrone 3-O-(beta-D-glucuronate) + UDP + H(+)


name: NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)


name: PI3K gain of function mutants phosphorylate PIP2 to PIP3 (Homo sapiens)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Mus musculus)


name: GSDME expression mediated by TP53, TP63 (Homo sapiens)


name: Formation of 4Fe-4S cluster on ISCA1:ISCA2 (Xenopus tropicalis)


name: ELOVL7 elongates ICS-CoA and Mal-CoA to 3ODC-CoA (Xenopus tropicalis)


name: Benzene is hydroxylated to phenol (Sus scrofa)


name: 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CMP + H(+)


name: ACVRL1 binds BMP9,BMP10 (Rattus norvegicus)


name: 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) => 3-dehydro-4alpha-methylzymosterol + CO2 + NADPH


name: ABL phosphorylates WAVEs (Xenopus tropicalis)


name: a (2S)-flavan-4-one + 2-oxoglutarate + O2 = a (2R,3R)-dihydroflavonol + succinate + CO2


name: factor XII + prekallikrein:kininogen:cell surface receptor -> prekallikrein:kininogen:cell surface receptor:factor XII (Rattus norvegicus)


name: SRC family kinases phosphorylate ERBB2 (Sus scrofa)


name: SCF(beta-TrCP) ubiquitinates p-GLI3 (Drosophila melanogaster)


name: SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Sus scrofa)


name: MeSeO2H is reduced to MeSeOH by TXNRD1 (Caenorhabditis elegans)


name: activation of class I ribonucleotide reductase activity


name: Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Rattus norvegicus)


name: 4beta-carboxy-4alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP(+) = 3-dehydro-4alpha-methylzymosterol + CO2 + NADPH


name: N-methyl-D-dopa + O2 <=> (3R)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2


name: 5-methyl-CMP + diphosphate + H(+) => 5-methyl-CTP + H2O


name: an N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine <=> an N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP + H(+)


name: extracellular matrix structural constituent conferring tensile strength


name: an N-(acyl)-sphingosylphosphocholine(in) + ATP + H2O => an N-(acyl)-sphingosylphosphocholine(out) + ADP + phosphate + H(+)


name: (19E)-geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + NADPH


name: Phosphorylated TAK1 leaves activated TLR receptor complex (Bos taurus)


name: Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5B at the plasma membrane (Xenopus tropicalis)


name: eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Sus scrofa)


name: Removal of siRNA passenger strand (Caenorhabditis elegans)


name: (S)-oxalosuccinate + H(+) = 2-oxoglutarate + CO2


name: FXI + kininogen -> FXI:kininogen (Xenopus tropicalis)


name: 4-methylcholesta-8(9),24-dien-3beta-ol is oxidized to 4-carboxycholesta-8(9),24-dien-3beta-ol (Homo sapiens)


name: CDP-D-glucose => CDP-4-dehydro-6-deoxy-D-glucose + H2O


name: (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(in) + ATP + H2O => (4Z,15Z)-bilirubin IXalpha C8,C12-beta-D-bisglucuronoside(out) + ADP + phosphate + H(+)


name: Adenylate cyclase converts ATP into cyclic AMP (Drosophila melanogaster)


name: 3 malonyl-CoA + acetyl-CoA + 2 H(+) <=> orsellinate + 3 CO2 + 4 CoA


name: a dicarboxylate + NADH + 2 H(+) => an omega-oxo fatty acid + NAD(+) + H2O


name: africanol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: L-methionine = 2-aminobut-2-enoate + methanethiol


name: WG, FZ and ARR bind to each other (Drosophila melanogaster)


name: a 1,2-diacyl-sn-glycerol(in) = a 1,2-diacyl-sn-glycerol(out)


name: carbamoyl phosphate + L-aspartate => N-carbamoyl-L-aspartate + phosphate + H(+)


name: SUMOylation of HDAC1 with SUMO1 (Bos taurus)


name: (S)-methylmalonyl-CoA + Na(+)(in) + H(+)(out) => propanoyl-CoA + Na(+)(out) + CO2


name: prostaglandin E1(in) + 2 (S)-lactate(out) => prostaglandin E1(out) + 2 (S)-lactate(in)


name: spermine + O2 + H2O = 3-aminopropanal + spermidine + H2O2


name: SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Danio rerio)


name: glutamine + H2O => glutamate + NH4+ (GLS) (Drosophila melanogaster)


name: I(1,3,4,5,6)P5 transports from the nucleus to the cytosol (Canis familiaris)


name: Active LTK recruits GRB2:SOS1 (Mus musculus)


name: Acireductone is oxidized to MOB (Homo sapiens)


name: a (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => an (8Z,11Z,14Z,17Z)-eicosatetraenoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: KAT5 acetylates ATM at shortened telomeres (Sus scrofa)


name: inositol hexakisphosphate kinase activity


name: MAPDA hydrolyzes N6-methyl-dAMP to dIMP and methylamine (Xenopus tropicalis)


name: PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Bos taurus)


name: MIB2 ubiquitinates CFLAR  (Mus musculus)


name: 4-deoxy-Delta(4)-beta-D-GlcpA2S-(1->3)-beta-D-GalpNAc + H2O <=> 5-dehydro-4-deoxy-2-O-sulfo-D-glucuronate + N-acetyl-beta-D-galactosamine


name: SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Bos taurus)


name: 4-cholesten-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-7alpha,24(S)-diol-3-one (Drosophila melanogaster)


name: Ubiquitinated DVL1 is degraded by the proteasome (Mus musculus)


name: aspartic acid methylthiotransferase activity


name: propanoyl-CoA + hydrogencarbonate + ATP = (S)-methylmalonyl-CoA + ADP + phosphate + H(+)


name: TP53 in complex with EP300, PRMT1 and CARM1 binds the GADD45A promoter (Homo sapiens)


name: PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)


name: vitamin B6 transmembrane transporter activity


name: K63polyUb-IRAK1 dissociates (Mus musculus)


name: Interaction of integrin alpha9beta1 with Tenascin-C (Homo sapiens)


name: cyclopolic acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 5-hydroxy-4-(hydroxymethyl)-7-methoxy-6-methylphthalide + reduced [NADPH--hemoprotein reductase] + O2


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + O2 = (2E,5Z,8Z,11Z,14Z,17Z)-eicosahexaenoyl-CoA + H2O2


name: 26Sproteasome degrades K48polyUb-NIK (Xenopus tropicalis)


name: an L-alpha-amino acid + acetyl-CoA => an N-acetyl-L-alpha-amino acid + CoA + H(+)


name: L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+) => tRNA(Trp) + L-tryptophan + ATP


name: Phospho-Chico: Activated DINR binds p60:Dp110 (Drosophila melanogaster)


name: Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) (Xenopus tropicalis)


name: sn-glycerol 1-phosphate + all-trans-heptaprenyl diphosphate => 3-heptaprenyl-sn-glycero-1-phosphate + diphosphate


name: Pro-HNP1-4 are cleaved to biologically active defensin (Homo sapiens)


name: FPRL2 receptor binds a wide range of ligands (Danio rerio)


name: CYSLT2 binds LTC4,LTD4,LTE4 (Rattus norvegicus)


name: Caspase-mediated cleavage of Lamin A (Sus scrofa)


name: 26S proteasome processes p-7S-p100:RELB to form p52:RELB (Rattus norvegicus)


name: 3-hydroxy-3-methylglutarate + malonyl-CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + malonate


name: cyclohexanone + A => cyclohex-2-enone + AH2


name: 4-hydroxybenzoate + phosphate + H(+) = phenyl phosphate + CO2 + H2O


name: NADPH transfers electrons to FDXR (Mus musculus)


name: OXCT dimers transfer CoA from SUCC-CoA to ACA, forming ACA-CoA (Rattus norvegicus)


name: PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Homo sapiens)


name: 6 malonyl-CoA + acetyl-CoA + 6 H(+) = nor-toralactone + 6 CO2 + 7 CoA + 2 H2O


name: a 1-acyl-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-acyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA


name: Formation of Cyclin A:Cdk2 complexes (Homo sapiens)


name: type I inositol-polyphosphate phosphatase activity


name: B4GALTs transfer Gal to the keratan chain (Bos taurus)


name: Trimerization of HSF1 in the nucleus (Bos taurus)


name: Alpha-defensin dimers multimerize to form a pore complex (Rattus norvegicus)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine <=> 1-O-acyl-N-(acetyl)-sphing-4-enine + 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)


name: N,N-dimethylglycine(in) + Na(+)(in) => N,N-dimethylglycine(out) + Na(+)(out)


name: 3-isopropylcatechol + NAD(+) + H2O => 2-isopropylphenol + NADH + O2 + H(+)


name: Prolactin receptor ligands bind the prolactin receptor (Mus musculus)


name: apigenin 7-O-beta-D-glucoside + UDP + H(+) => apigenin + UDP-alpha-D-glucose


name: 4-hydroxy-6-methylpretetramide + NADPH + O2 <=> 4-dedimethylamino-4-oxo-anhydrotetracycline + NADP(+) + H2O


name: M mRNA is translated into protein M (Homo sapiens)


name: 3-amino-2,3-dideoxy-scyllo-inosose + NADPH + H(+) => 2-deoxy-scyllo-inosamine + NADP(+)


name: Ca2+ influx into the post-synaptic cell (Gallus gallus)


name: histone H3K18 deacetylase activity, NAD-dependent


name: 2-octanone + NADPH + H(+) <=> (2R)-octan-2-ol + NADP(+)


name: (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)


name: activation of mucopeptide N-acetylmuramoylhydrolase activity


name: activation of raffinose biosynthetic process


name: regulation of NFAT protein import into nucleus


name: Release of Cytochrome c from mitochondria (Canis familiaris)


name: Endosomal TLRs pass through the Golgi (Danio rerio)


name: Mn(2+)(in) + ATP + H2O = Mn(2+)(out) + ADP + phosphate + H(+)


name: tetracosanoyl-CoA + taurine <=> N-tetracosanoyl-taurine + CoA + H(+)


name: 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus (Homo sapiens)


name: PGD decarboxylates 6-phospho-D-gluconate (Danio rerio)


name: WWOX binds ERBB4s80 (Drosophila melanogaster)


name: Crk binds to the active PDGF receptor (Rattus norvegicus)


name: VRAC heteromer transports I-, Cl- from cytosol to extracellular region (Drosophila melanogaster)


name: PBRM1-containing ATPase complex binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1:ARID2:BRD&:PHF10 (Bos taurus)


name: 5-hydroxyanthranilate + (E)-4-coumaroyl-CoA = avenanthramide A + CoA


name: 4-phospho-D-erythronate + NADH + 2 H(+) => D-erythrose 4-phosphate + NAD(+) + H2O


name: TBXAS1 isomerises PGH2 to TXA2 (Mus musculus)


name: Oxidized DNAJA1 binds HSPA1A,B (HSP70) displacing HSF1 (Mus musculus)


name: p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Danio rerio)


name: 4alpha-methylzymosterol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxyzymosterol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: phenanthrene-9,10-diol + NADP(+) => 9,10-phenanthroquinone + NADPH + H(+)


name: NNMT transfers CH3 from SAM to NAM to form MNA (Canis familiaris)


name: AH2 + NH4(+) + O2 = hydroxylamine + A + H2O + H(+)


name: a 1,2-diacylglycerol + H2O = a 1-acylglycerol + a fatty acid + H(+)


name: eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate <=> 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA


name: OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1 (Mus musculus)


name: 6-methylsalicylate + H(+) = 3-methylphenol + CO2


name: WNTs are secreted in exosomes (Sus scrofa)


name: (2S)-4-acetamido-2-aminobutanoate = L-ectoine + H2O


name: Src activation following P2Y purinoceptor activation (Gallus gallus)


name: RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Drosophila melanogaster)


name: RBFOX3 (NeuN) gene expression is stimulated by NPAS4 (Homo sapiens)


name: (2R,3R,5S,6R)-6-(methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + methylcob(III)alamin + S-adenosyl-L-methionine <=> (2R,3R,5S,6R)-6-(ethyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + cob(III)alamin + 5'-deoxyadenosine + L-methionine


name: ABCG2 transports Cipro from intestinal cell to extracellular space (Caenorhabditis elegans)


name: SPAM1 Binds Hyaluronic Acid (Xenopus tropicalis)


name: ent-kaur-16-ene + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) = ent-kaur-16-en-19-oate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O


name: N6AMT2 transfers 3xCH3 from 3xAdoMet to EEF1A (Caenorhabditis elegans)


name: Activation of proMMP10 (Xenopus tropicalis)


name: LC3 de-lipidation by ATG4 (Mus musculus)


name: 3-hexadecanoyl-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine <=> 1-(9Z)-octadecenoyl-3-hexadecanoyl-sn-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: 2-amino-4,7-dihydroxypteridine + chemical entity => 2-amino-4-hydroxypteridine + O2


name: negative regulation of syringal lignin biosynthetic process


name: MLXIPL:MLX binds PKLR gene promoter (Homo sapiens)


name: cob(II)yrinate a,c diamide + apo-[corrinoid adenosyltransferase] => cob(II)yrinate a,c diamide-[corrinoid adenosyltransferase]


name: a beta-D-Gal-(1<->1')-ceramide + 3'-phosphoadenylyl sulfate <=> 1-(3-O-sulfo-beta-D-galactosyl)-ceramide + adenosine 3',5'-bisphosphate + H(+)


name: CANX dissociates from IL12A:EBI3 (Canis familiaris)


name: The UDP/CysLT (P2Y17) receptor can bind UTP (Gallus gallus)


name: L-glutamyl-tRNA(Glu) + L-arginyl-tRNA(Arg) = cyclo(L-arginyl-L-glutamyl) + tRNA(Glu) + tRNA(Arg) + 2 H(+)


name: AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it (Drosophila melanogaster)


name: chloroethene + reduced [NADPH--hemoprotein reductase] + O2 <=> chloroethylene oxide + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 4 semiviriditoxin + O2 = 2 (M)-viriditoxin + 2 H2O


name: 3' incision by ERCC5 (XPG) in TC-NER (Danio rerio)


name: (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + H2O = (-)-geosmin + acetone


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Rattus norvegicus)


name: JMJD6 demethylates Me2sR4-HIST1H4 (Drosophila melanogaster)


name: a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O => a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: E2 enzyme UBE2N:UBE2V1 binds ubiquitin (Homo sapiens)


name: VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Sus scrofa)


name: 2 a 1-acyl-sn-glycero-3-phosphocholine => sn-glycerol 3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: EXO1 excises single strand DNA surrounding a U:G mismatch (Sus scrofa)


name: SLC4A1,2,3 exchanges HCO3- for Cl- (Drosophila melanogaster)


name: a D-glucoside + NAD(+) => a 3-dehydro-D-glucoside + NADH + H(+)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(S)-HDHA to RvD1 or RvD2 (Drosophila melanogaster)


name: LIPs hydrolyze TG to DAG and LCFA (Gallus gallus)


name: EGFR non-clathrin mediated endocytosis (Rattus norvegicus)


name: Co-repressor complex dissociates from the transcription unit of the ABCA1 gene  (Canis familiaris)


name: TYSND1 cleaves TYSND1 (Dictyostelium discoideum)


name: (2S)-naringenin + reduced [NADPH--hemoprotein reductase] + O2 => (2S)-2-hydroxynaringenin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: propanoate(out) + dehydroepiandrosterone 3-sulfate(in) => propanoate(in) + dehydroepiandrosterone 3-sulfate(out)


name: NNT dimer transfers proton from NADPH to NAD+ (Caenorhabditis elegans)


name: PI3P is dephosphorylated to PI by MTMR9-bound MTMR8 or MTMR6 at the plasma membrane (Danio rerio)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1,2-di-(9Z-octadecenoyl)-sn-glycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O <=> 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + choline + H(+)


name: GBP1:GTP binds LPS on the bacterial surface (Bos taurus)


name: dibenzothiophene desulfurization enzyme B


name: 25-hydroxyvitamin D3 sulfate(out) + n H(+)(out) = 25-hydroxyvitamin D3 sulfate(in) + n H(+)(in)


name: 3-hydroxypropanal + NADP(+) + H2O <=> 3-hydroxypropanoate + NADPH + 2 H(+)


name: BH2 binding can lead to eNOS uncoupling (Homo sapiens)


name: N(tele)-phospho-L-histidyl-[protein] + H2O <=> L-histidyl-[protein] + phosphate


name: preaustinoid A1 + 2-oxoglutarate + O2 = preaustinoid A2 + succinate + CO2 + H2O


name: ALDH3B2 oxidises HXAL to PALM (Drosophila melanogaster)


name: ganglioside biosynthetic process via lactosylceramide


name: Phosphoinositide 3-Kinase delta Inhibitors [MoA]


name: CUL5 mediates ubiquitination of ERBB2 (Bos taurus)


name: Somatostatin receptors bind somatostatin and cortistatin (Gallus gallus)


name: N(2')-acetylgentamicin C1a + CoA + H(+) => gentamicin C1a + acetyl-CoA


name: NS1 dimer is ubiquitinated (Homo sapiens)


name: dihydroprecondylocarpine acetate + NADPH => (+)-vincadifformine + acetate + NADP(+)


name: BAR domain proteins recruit dynamin (Sus scrofa)


name: ALAS condenses SUCC-CoA and Gly to form dALA (Drosophila melanogaster)


name: (S)-(2E,6E,10E)-epoxygeranylgeranyl-triacetate lactone = sartorypyrone D


name: TTYH2/3 transport cytosolic Cl- to extracellular region (Mus musculus)


name: (+)-epi-isozizaene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (5R)-albaflavenol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: [sulfur-carrier protein]-C-terminal-Gly-aminoethanethioate + AMP + diphosphate => [sulfur-carrier protein]-C-terminal Gly-Gly + hydrogen sulfide + ATP


name: PIP3 recruits AKT to the membrane (Danio rerio)


name: MUL1 ubiquitinates UBXN7 (Drosophila melanogaster)


name: MRRF binds 55S ribosome:mRNA:tRNA (Gallus gallus)


name: 5-dodecanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => dodecane + reduced [NADPH--hemoprotein reductase] + O2


name: activation of selenium-glutathione peroxidase activity


name: 1-propanol + acetyl-CoA = propyl acetate + CoA


name: PLA1A hydrolyses PS to 2-acyl LPS (Mus musculus)


name: positive regulation of adenosylcobalamin-dependent ribonucleotide reductase activity


name: p-S295-PDE3B hydrolyses cAMP to AMP (Mus musculus)


name: Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine]2 + H2O + H(+) => Fe(III)-[N-(2,3-dihydroxybenzoyl)-L-serine] + N-(2,3-dihydroxybenzoyl)-L-serine


name: MARK3 phosphorylates KSR1 (Caenorhabditis elegans)


name: a 14alpha-methyl steroid + 6 reduced [2Fe-2S]-[ferredoxin] + 3 O2 + 5 H(+) => a Delta(14) steroid + formate + 6 oxidized [2Fe-2S]-[ferredoxin] + 4 H2O


name: dATP + H2O <=> 2'-deoxyadenosine + triphosphate + H(+)


name: 2 Fe(II)-[leghemoglobin] + NAD(+) + H(+) => 2 Fe(III)-[leghemoglobin] + NADH


name: Hydrolysis of PIP2 by PLCG (Drosophila melanogaster)


name: Dual mechanism MAPK inhibitors bind MAPKs (Homo sapiens)


name: G3P is acylated to 1-acyl LPA by AGPAT6 (Xenopus tropicalis)


name: SPPL2a/b cleaves TNF(1-76) (Xenopus tropicalis)


name: DAG is metabolized by DAGL to 2-AG (Homo sapiens)


name: CBL ubiquitinates Sprouty (Rattus norvegicus)


name: xanthosine transmembrane transporter activity


name: (S)-2,3-diaminopropanoate + citrate + ATP <=> 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + AMP + diphosphate


name: LC3 de-lipidation by ATG4 (Drosophila melanogaster)


name: KDM6B binds iron (Dictyostelium discoideum)


name: L-threonyl-tRNA(Ile) + H2O => tRNA(Ile) + L-threonine


name: 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + phosphate


name: HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Gallus gallus)


name: Cleavage of p-STK4 (p-MST1) by caspase 3 (Gallus gallus)


name: NFKB1:RELA translocates from the cytosol to the nucleus (Rattus norvegicus)


name: questinol + S-adenosyl-L-homocysteine + 2 H(+) => omega-hydroxyemodin + S-adenosyl-L-methionine


name: Internalization of ubiquitinated FLT3 (Sus scrofa)


name: N,N-dihydroxy-L-hexahomomethionine + H(+) <=> (E)-9-(methylsulfanyl)nonanal oxime + CO2 + H2O


name: Core CPA complex binds capped pre-mRNA (Drosophila melanogaster)


name: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP <=> 8-desmethylnovobiocic acid + AMP + diphosphate


name: L-fuconate => 2-dehydro-3-deoxy-L-fuconate + H2O


name: 8-oxo-GMP + diphosphate + H(+) => 8-oxo-GTP + H2O


name: erythrodiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => beta-amyrin + reduced [NADPH--hemoprotein reductase] + O2


name: PI(3,5)P2 transports from the early endosome membrane to the Golgi membrane (Homo sapiens)


name: SUMOylation of UBE2I with SUMO1 (Bos taurus)


name: HMGCS1 condenses Ac-CoA and ACA-CoA to form bHMG-CoA (Dictyostelium discoideum)


name: PTK6 phosphorylates BCAR1 (Mus musculus)


name: LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Danio rerio)


name: Inactivation of APC/C via CDC20 sequestration (Homo sapiens)


name: AMP + ATP <=> ADP + ADP [AK2] (Canis familiaris)


name: [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + NADPH + H(+) => [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + phosphate + NADP(+)


name: Some HSPGs are secreted to the plasma membrane (Canis familiaris)


name: Extracellular KSPG translocates to the lysosome for degradation (Drosophila melanogaster)


name: Rap1 signal termination by Rap1GAPs (Drosophila melanogaster)


name: an N-acylsphing-4-enine 1-phosphate + H2O <=> an N-acylsphing-4-enine + phosphate


name: SLC25A1 may exchange mitochondrial PEP for cytosolic anion (Bos taurus)


name: [(1->4)-alpha-D-galacturonosyl methyl ester](n) + n H2O <=> [(1->4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)


name: (2E,9Z)-hexadecadienoyl-CoA + H2O => (3S)-hydroxy-(9Z-hexadecenoyl)-CoA


name: HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)


name: a beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminyl derivative + CMP + H(+)


name: TRADD:TRAF2:RIP1 binds FADD (Bos taurus)


name: Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Drosophila melanogaster)


name: Autoproteolytic cleavage of Hh precursors (Mus musculus)


name: RhCG mediates ammonium influx into kidney collecting duct cells (Mus musculus)


name: sulfite(in) + sulfate(out) => sulfite(out) + sulfate(in)


name: oxidized [electron-transfer flavoprotein] + (9Z)-octadecenoyl-CoA + H(+) => (2E,9Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: lipid A 1,4'-bis(2-aminoethyl diphosphate) (E. coli) + a 1,2-diacyl-sn-glycerol => lipid A hexaacyl 1-(2-aminoethyl diphosphate) (E. coli) + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+)


name: dimethyl sulfide + NADH + O2 + H(+) <=> methanethiol + formaldehyde + NAD(+) + H2O


name: beta-D-glucose + acetyl-CoA <=> 6-O-acetyl-beta-D-glucose + CoA


name: 3-oxo-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + NADPH + H(+) => (3R)-hydroxy-(13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + NADP(+)


name: 7-oxocholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) <=> (25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 oxidized [adrenodoxin] + H2O


name: 3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-methionine <=> 3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)


name: RUNX1 binds SIN3A,(SIN3B) co-repressor (Bos taurus)


name: 10-hydroxy-(11E)-octadecenoate => (9Z,11E)-octadecadienoate + H2O


name: GRHL family transcription factors dimerize (Bos taurus)


name: a 3-acylpyruvate + H2O => a carboxylate + pyruvate + H(+)


name: IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Canis familiaris)


name: (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H(+) => 2-dehydro-3-deoxy-D-gluconate + NADP(+)


name: an N-acyl-aromatic L-alpha-amino acid + H2O => an aromatic L-alpha-amino acid + a carboxylate


name: GSSeSG is reduced to GSSeH and GSH by GSR (Homo sapiens)


name: L-alanyl-L-leucine + H2O = L-leucine + L-alanine


name: 8-demethyl-8-alpha-L-rhamnosyl-tetracenomycin C + dTDP + H(+) => 8-demethyltetracenomycin C + dTDP-beta-L-rhamnose


name: L-aspartate 4-semialdehyde + reduced 2[4Fe-4S]-[ferredoxin] + hydrogen sulfide + 3 H(+) <=> oxidized 2[4Fe-4S]-[ferredoxin] + L-homocysteine + H2O


name: PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Danio rerio)


name: GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P (Caenorhabditis elegans)


name: NANP dephosphorylates Neu5Ac-9-P to Neu5Ac (Bos taurus)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Mus musculus)


name: 5-hydroxymethylfurfural + O2 <=> 2,5-diformylfuran + H2O2


name: (E)-anol + acetate + NADP(+) <=> (E)-coumaryl acetate + NADPH


name: positive regulation of neurotrophin TRK receptor signaling pathway


name: PTGS2 dimer oxidises DPAn-3 to 13(R)-HDPAn-3 (Bos taurus)


name: MAOB inhibitors bind MAOB:FAD (Bos taurus)


name: propanoyl-CoA + glyoxylate + H2O => 2-hydroxyglutarate + CoA + H(+)


name: GALNT3 transfers GalNAc to FGF23 (Drosophila melanogaster)


name: NFE2L2 dependent ABCC1 expression (Homo sapiens)


name: NSF and SNAPs bind cis-SNARE at the ER membrane (Homo sapiens)


name: AP4 transports APP from trans-Golgi network to endosome lumen (Plasmodium falciparum)


name: CALCA(83-119) binds CALCA antibodies (Sus scrofa)


name: Ionotropic Glutamate Receptor Interactions


name: nicotinate + NADP(+) = NAADP(+) + nicotinamide


name: TMEM55B translocates to the nucleus (Rattus norvegicus)


name: C3(H2O):Factor Bb cleaves C3 to C3b and C3a (Danio rerio)


name: MIOX oxidises Ins to GlcA (Mus musculus)


name: CASP5 cleaves IL1B at D27 (Homo sapiens)


name: GMP + 2 phosphate + 2 H(+) => GTP + 2 H2O


name: Rab5-mediated recruitment of class III PI3K to TLR9 (Sus scrofa)


name: octadecanoate + ATP + H(+) = octadecanoyl-AMP + diphosphate


name: 7-deoxycylindrospermopsin + 2-oxoglutarate + O2 = cylindrospermopsin + succinate + CO2


name: Catalysing the translocation carbohydrates and their derivatives


name: p-STAT4 dissociates from IL12RB2:IL12RB2 receptor (Gallus gallus)


name: Loading of claspin onto DNA during replication origin firing (Drosophila melanogaster)


name: DCAKD phosphorylates DP-CoA (Plasmodium falciparum)


name: glycero-2-phosphocholine + H2O = phosphocholine + glycerol + H(+)


name: a 1-acyl-sn-glycero-3-phosphocholine(in) + Na(+)(in) <=> a 1-acyl-sn-glycero-3-phosphocholine(out) + Na(+)(out)


name: Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Homo sapiens)


name: (S)-2-amino-6-oxohexanoate + H2O2 + NH4(+) => L-lysine + O2 + H2O


name: L-histidyl-L-proline diketopiperazine(in) = L-histidyl-L-proline diketopiperazine(out)


name: an inositol phosphomannosylnositol-1-phospho-N-acylsphingoid base + a 1,2-diacyl-sn-glycerol => a mannosylinositol-1-phospho-N-acyl-sphingoid base + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)


name: isoxazolin-5-one + O-acetyl-L-serine = 3-(5-oxoisoxazolin-4-yl)-L-alanine + acetate + H(+)


name: p-PKR dimer phosphorylates PTPN2 (Sus scrofa)


name: DIBOA beta-D-glucoside + H2O = DIBOA + D-glucose


name: O-propanoyl-(R)-carnitine(out) + (R)-carnitine(in) => O-propanoyl-(R)-carnitine(in) + (R)-carnitine(out)


name: prephenate + H(+) = 3-[(4R)-4-hydroxycyclohexa-1,5-dien-1-yl]-2-oxopropanoate + CO2


name: Proteasome-dependent degradation of ubiquitinated CDH1 (Danio rerio)


name: S-hydroxy-L-cysteinyl-[peroxiredoxin] + [protein]-disulfide + ADP + phosphate => S-hydroxy-S-oxy-L-cysteinyl-[peroxiredoxin] + [protein]-dithiol + ATP


name: CA1:Zn2+,CA2:Zn2+ hydrate CO2 to HCO3- (Danio rerio)


name: OPTN binds CASP8 (Drosophila melanogaster)


name: Binding of GRB2:GAB1 complex to p-EGFRvIII mutant (Homo sapiens)


name: DPH5 transfers four methyl groups from AdoMet to aminocarboxypropyl EEF2 (Bos taurus)


name: MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Mus musculus)


name: ferrioxamine uptake transmembrane transporter activity


name: Arachidonate is epoxidated to 8,9-EET by CYP(5) (Canis familiaris)


name: SARDH:FAD oxidatively demethylates SARC to Gly (Bos taurus)


name: 1-O-alkyl-3-acylglycerol + an acyl-CoA <=> 1-O-alkyl-2,3-diacylglycerol + CoA


name: Phosphorylated MKK3/MKK6 migrates to nucleus (Caenorhabditis elegans)


name: 2-dehydro-3-deoxy-D-gluconate <=> D-glyceraldehyde + pyruvate


name: a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine


name: IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Mus musculus)


name: a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)


name: arginine + H2O => ornithine + urea [ARG2] (Homo sapiens)


name: HSD11B2 dehydrogenates PREDL to PREDN (Bos taurus)


name: SALL4 recruits NuRD to PTEN gene (Danio rerio)


name: STING binds TRIM32 or TRIM56  (Mus musculus)


name: XDH dehydrogenates xanthine to form urate (Drosophila melanogaster)


name: N(6)-acyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]


name: ROCK1,2 bind ROCKi (Caenorhabditis elegans)


name: medium-chain fatty acid-CoA ligase activity


name: 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADH + O2 + H(+) <=> 4beta-hydroxymethyl-4alpha-methylzymosterol + NAD(+) + H2O


name: Ubiquitination of Emi1 by SCF-beta-TrCP (Mus musculus)


name: N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + O2 <=> N-(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoyl-glycine


name: D-glucose 6-phosphate + H2O => D-glucose + phosphate


name: positive regulation of ubiquitin-dependent protein catabolic process


name: Transport of N-glycosylated CD274 to Golgi (Mus musculus)


name: ATP binds G-protein beta associated TRiC/CCT (Rattus norvegicus)


name: (indol-3-yl)acetyl-AMP + CoA <=> (indol-3-yl)acetyl-CoA + AMP + H(+)


name: Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Rattus norvegicus)


name: CARM1 methylates arginine-18 (H3R17) of histone H3 (Homo sapiens)


name: 3-hydroxy-4-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) <=> methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + 3,4-dihydroxybenzoate


name: SLC2A5 transports fructose from extracellular region to cytosol (Caenorhabditis elegans)


name: 3-geranyl-3-[(Z)-2-isocyanoethenyl]-1H-indole <=> 12-epi-hapalindole U


name: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)


name: Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Bos taurus)


name: Activated FGFR2:p-SHC1 binds GRB2:SOS1 (Drosophila melanogaster)


name: D-galactose 6-phosphate + NAD(+) => 6-phospho-D-galactono-1,5-lactone + NADH + H(+)


name: (S)-3-Hydroxytetradecanoyl-CoA+NAD => 3-Oxotetradecanoyl-CoA+NADH+H (Danio rerio)


name: L-valine(out) + ATP + H2O = L-valine(in) + ADP + phosphate + H(+)


name: Hydrolysis of choloyl-CoA to cholate and CoASH (Canis familiaris)


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Sus scrofa)


name: CRAT transfers ISB to CAR (Drosophila melanogaster)


name: cholesterol dehydrogenase (NAD+) activity


name: 3-dehydro-L-gulonate + H(+) => L-xylulose + CO2


name: 16alpha,17beta-estriol 3-O-(beta-D-glucuronate)(in) + ATP + H2O = 16alpha,17beta-estriol 3-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)


name: 2 reduced [4Fe-4S]-[ferredoxin] + NADP(+) + H(+) => 2 oxidized [4Fe-4S]-[ferredoxin] + NADPH


name: 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+) => a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O


name: a very-long-chain 3-oxoacyl-CoA + NADH + H(+) => a very-long-chain (3R)-3-hydroxyacyl-CoA + NAD(+)


name: a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O => a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: tert-butyl hydroperoxide + 2 glutathione = tert-butanol + glutathione disulfide + H2O


name: (1S,3R,5S)-sabinol + NADP(+) + H2O => (1R,5R)-sabinene + NADPH + O2 + H(+)


name: 6-phospho-N-acetyl-beta-D-muramate-(1->4)-N-acetyl-D-glucosamine + H2O => N-acetyl-D-muramate 6-phosphate + N-acetyl-D-glucosamine


name: down regulation of PERK signaling in response to endoplasmic reticulum stress


name: (9Z)-octadecenoyl-CoA + H2O = (9Z)-octadecenoate + CoA + H(+)


name: SLC5A6 transports vitamins from extracellular region to cytosol (Sus scrofa)


name: ABO-B:Mn2+ transfers Gal to H antigen-RBC to form B antigen-RBC (Xenopus tropicalis)


name: (2E,6E,10E)-geranylgeranyl diphosphate = (-)-cyatha-3,12-diene + diphosphate


name: GMP(in) + NAD(+)(out) <=> GMP(out) + NAD(+)(in)


name: negative regulation of fumigaclavine C biosynthetic process


name: p-PKR dimer phosphorylates ILF3:ILF2 (Canis familiaris)


name: COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Mus musculus)


name: The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Mus musculus)


name: DAG and Ca+2 bind to PKC and tether it to membrane (Gallus gallus)


name: keto-L-fructose + NADH + H(+) => L-glucitol + NAD(+)


name: PI3K binds membrane-associated estrogen receptors (Danio rerio)


name: inhibition of protein catabolic process in the vacuole


name: methylglyoxal + acetoacetate + H(+) = 3-hydroxyhexane-2,5-dione + CO2


name: 11-hydroxycucurbitadienol + reduced [NADPH--hemoprotein reductase] + O2 <=> 11-oxocucurbitadienol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: Dopamine is oxidised to noradrenaline (Mus musculus)


name: 4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Xenopus tropicalis)


name: ERBB3 binds neuregulins (Canis familiaris)


name: O-[5'-(adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein] + ATP = O-[5'-(adenylyl-(5'->3')-adenylyl-(5'->3')-adenylyl)]-L-tyrosyl-[protein] + diphosphate


name: PEX5S,L binds cargo proteins containing PTS1 (Homo sapiens)


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Bos taurus)


name: ALOX5 dehydrogenates 7,17-diHp-DPAn-3 to 7,8-epoxy,17-HDPAn-3 (Homo sapiens)


name: TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex (Homo sapiens)


name: SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Gallus gallus)


name: dihydrorhizobitoxine + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => rhizobitoxine + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: p-PKR dimer phosphorylates TP53 tetramer (Xenopus tropicalis)


name: Diiodinated tyrosine can be deiodinated (Drosophila melanogaster)


name: DNA polymerases delta, epsilon or kappa bind the GG-NER site (Danio rerio)


name: CLCN7:OSTM1 exchanges Cl- for H+ (Xenopus tropicalis)


name: Ca permeable AMPA receptor ligand binding (Gallus gallus)


name: decanoate ester + H2O => decanoate + an aliphatic alcohol + H(+)


name: tetradecane + reduced [NADPH--hemoprotein reductase] + O2 = 7-tetradecanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Orexin 2 receptor can bind orexin-B neuropeptide (Sus scrofa)


name: Displacement of TDG glycosylase by APEX1 at the AP site (Drosophila melanogaster)


name: ALOX15 oxidises DPAn-6 to 17(S)-HDPAn-6 and 10(S),17(S)-diHDPAn-6 (Canis familiaris)


name: sulfate(out) + phosphate(in) + H(+)(in) => sulfate(in) + phosphate(out) + H(+)(out)


name: Dissociation of phosphorylated 4EBP1 from eIF4E (Gallus gallus)


name: BRAP binds RAS:GTP (Drosophila melanogaster)


name: ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Bos taurus)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Schizosaccharomyces pombe)


name: TRPA1 tetramer binds TRPA1 antagonists (Danio rerio)


name: S-(9Z-octadecenoyl)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => (9Z)-octadecenoyl-CoA + H2O


name: L-fucose(in) + H(+)(in) <=> L-fucose(out) + H(+)(out)


name: 2 a menaquinol + O2 + n H(+)(in) => 2 a menaquinone + 2 H2O(in) + n H(+)(out)


name: Thrombin, ELANE cleave C5 (Canis familiaris)


name: GDIs block activation of RHOB (Sus scrofa)


name: 2xPPCS ligates PPanK with Cys (Danio rerio)


name: SULT1A3,4 dimers sulfate DA to DAOS (Canis familiaris)


name: 19-oxo-androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 = estrone + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: 1-hexadecanoyl-2-(8Z,11Z,14Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol <=> cholesteryl (8Z,11Z,14Z)-eicosatrienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: (9Z,12Z,15Z)-octadecatrienamide + H2O <=> (9Z,12Z,15Z)-octadecatrienoate + NH4(+)


name: 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine


name: Phosphorylation of Cdh1 by Cyclin B1:Cdc2 (Drosophila melanogaster)


name: HGD dioxygenates homogentisate (Drosophila melanogaster)


name: (3S)-hydroxytetradecanoyl-CoA + NAD(+) <=> 3-oxotetradecanoyl-CoA + NADH + H(+)


name: D-fructose 6-phosphate + D-erythrose 4-phosphate  <=>  sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate (Rattus norvegicus)


name: isophthalate + ATP + CoA = isophthalyl-CoA + AMP + diphosphate


name: pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate (Drosophila melanogaster)


name: Arachidonate is hydroxylated to 20-HETE by CYP(3) (Bos taurus)


name: (4Z,7Z,10Z)-hexadecatrienoyl-CoA + O2 = (2E,4Z,7Z,10Z)-hexadecatetraenoyl-CoA + H2O2


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Mus musculus)


name: L-cysteine + L-arginine => N-amidino-L-cysteine + L-ornithine


name: NEIL3 resolves abasic site-induced ICLs (Homo sapiens)


name: (25R)-3beta-hydroxycholest-5-en-7-one-26-oate + 2 oxidized [adrenodoxin] + H2O => (25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 reduced [adrenodoxin] + O2 + H(+)


name: 3-deoxyglucosone + L-lysyl-[protein] + phosphate => N(6)-(3-O-phospho-D-fructosyl)-L-lysyl-[protein] + H2O


name: 12-hydroxyoctadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 12,18-dihydroxyoctadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (E)-4-coumarate + H(+) => 4-vinylphenol + CO2


name: 2-methylbutyl hexanoate + CoA => 2-methylbutan-1-ol + hexanoyl-CoA


name: uridine(20) in tRNA + NADPH + H(+) => 5,6-dihydrouridine(20) in tRNA + NADP(+)


name: 7'-O-demethylcephaeline + S-adenosyl-L-methionine => cephaeline + S-adenosyl-L-homocysteine + H(+)


name: D-ribose + NADPH + H(+) => ribitol + NADP(+)


name: Hypochlorous acid (HOCL) reacts with Lys-monochloramine (Homo sapiens)


name: SLC6A4 binds TCAs and SSRIs (Danio rerio)


name: [(4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)-cyclohex-1-en-1-yl]methanol + reduced [NADPH--hemoprotein reductase] + O2 <=> (4S)-4-(5,5-dimethylcyclohex-1-en-1-yl)cyclohex-1-ene-1-carbaldehyde + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Homo sapiens)


name: activation of poly(A) synthetase activity


name: PHGDH tetramer dehydrogenates 3PG (Bos taurus)


name: Binding of ADAR2 homodimer to dsRNA duplex (Bos taurus)


name: 2 L-cysteine = S-sulfanyl-L-cysteine + L-alanine


name: Surface deployment of platelet dense granule membrane components (Homo sapiens)


name: reduced folate transmembrane transporter activity


name: 4-hydroxylamino-2,6-dinitrotoluene + 2 NADPH + 2 H(+) <=> 2,4-dihydroxylamino-6-nitrotoluene + 2 NADP(+) + H2O


name: UDP-N-acetyl-alpha-D-glucosamine + H2O <=> N-acetyl-alpha-D-glucosamine 1-phosphate + UMP + 2 H(+)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)


name: D-phenylalanyl-tRNA(Phe) + H2O <=> D-phenylalanine + tRNA(Phe) + H(+)


name: 4'-thymidylylamikacin + diphosphate => amikacin + dTTP


name: an L-N,N-dihydroxypolyhomomethionine + H(+) => an (E)-omega-(methylsulfanyl)-alkanal oxime + CO2 + H2O


name: DNA ligase I ligates single stranded nick in double stranded DNA (Canis familiaris)


name: 27-hydroxysterol binds ESR1, ESR2 (Gallus gallus)


name: KSRP binds AU-rich element in 3' UTR of mRNA (Sus scrofa)


name: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA => (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O


name: a 3'-end 2'-deoxyribonucleotide-3'-diphospho-5'-guanosine-DNA + H2O = a 3'-end 2'-deoxyribonucleotide 3'-phosphate-DNA + GMP + 2 H(+)


name: G mRNA is translated into membrane-bound G protein (Homo sapiens)


name: Activated TrkA receptor internalizes to endosomes (Danio rerio)


name: HTRA2 degrades APP (Amyloid-beta precursor protein) (Bos taurus)


name: RHOT2 binds effectors at the mitochondrial outer membrane (Caenorhabditis elegans)


name: Polyubiquitination of substrate (Gallus gallus)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + 2 oxidized [2Fe-2S]-[ferredoxin] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)


name: IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Bos taurus)


name: Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Danio rerio)


name: activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the  phospho-IkB (Gallus gallus)


name: CANX dissociates from IL12A:EBI3 (Rattus norvegicus)


name: 4-hydroxy-2-oxobutanal + L-lysyl-[protein] + phosphate => N(6)-(3-O-phospho-D-erythrulosyl)-L-lysyl-[protein] + H2O


name: Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Bos taurus)


name: Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Sus scrofa)


name: negative regulation of protein polyglycylation


name: N-benzoylglycine + CoA + H(+) => benzoyl-CoA + glycine


name: 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA (Homo sapiens)


name: GLYAT-like proteins transfer glycine to phenylacetyl-CoA (Sus scrofa)


name: Collagen type IV degradation by MMP2,3,4,9,10,12 (Rattus norvegicus)


name: SLC38A9 binds Ragulator:Rag dimers (Sus scrofa)


name: (2E,6E,10E)-geranylgeranyl diphosphate = tsukubadiene + diphosphate


name: Nef Binds and activates the Src-family tyrosine kinase Hck (Homo sapiens)


name: Phosphorylated SHC1 recruits GRB2:GAB2 (Sus scrofa)


name: histone H1K75 acetyltransferase activity


name: aklavinone + NADPH + O2 + H(+) => epsilon-rhodomycinone + NADP(+) + H2O


name: a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)


name: cis-Golgi cis-SNARE binds NSF and SNAPs (Canis familiaris)


name: PLC-gamma1 hydrolyses PIP2 (Canis familiaris)


name: PIAS1,2-1 SUMOylate NR5A2 with SUMO1 (Mus musculus)


name: 3-(methylsulfanyl)propanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> 3-(methylsulfanyl)acryloyl-CoA + reduced [electron-transfer flavoprotein]


name: UDP-4-deoxy-4-formamido-beta-L-arabinose + (6S)-5,6,7,8-tetrahydrofolate + H(+) => UDP-4-amino-4-deoxy-beta-L-arabinose + (6R)-10-formyltetrahydrofolate


name: glutamine + H2O => glutamate + NH4+ (GLS) (Danio rerio)


name: PDGFRs bind type II TKI (Drosophila melanogaster)


name: (6E)-8-oxogeraniol + NAD(+) <=> (6E)-8-oxogeranial + NADH + H(+)


name: PGM2:Mg2+ isomerises R1P to R5P (Saccharomyces cerevisiae)


name: 3-methylxanthine + NADPH + O2 + H(+) => xanthine + formaldehyde + NADP(+) + H2O


name: luteolin + S-adenosyl-L-methionine = luteolin 7-methyl ether + S-adenosyl-L-homocysteine + H(+)


name: misfolded CFTR is degraded by the 26S proteasome (Bos taurus)


name: voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential


name: p-Y705-STAT3, p-Y641-STAT6 dimerise (Dictyostelium discoideum)


name: SLCO2B1 has a narrow substrate specificity (Gallus gallus)


name: Factor B binds to surface-associated C3b (Mus musculus)


name: (2R,3R)-dihydrokaempferol + 2-oxoglutarate + O2 <=> kaempferol + succinate + CO2 + H2O + H(+)


name: (S)-selective hydroxynitrile lyase activity


name: Phosphorylation of Cx43 by c-src (Homo sapiens)


name: L-tryptophyl-tRNA(Trp) + L-arginyl-tRNA(Arg) => cyclo(L-arginyl-L-tryptophyl) + tRNA(Trp) + tRNA(Arg) + H(+)


name: SEMA6D binds to PLXNA1:TREM2:DAP12 (Canis familiaris)


name: cytidine(48) in tRNA precursor + S-adenosyl-L-methionine => 5-methylcytidine(48) in tRNA precursor + S-adenosyl-L-homocysteine + H(+)


name: 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + (2S)-2-aminobutanoate => 3-hydroxy-L-kynurenine + 2-oxobutanoate


name: Complement factor H binds to C3b (Gallus gallus)


name: indole-3-ethanol + NAD(+) => indole-3-acetaldehyde + NADH + H(+)


name: (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA (Bos taurus)


name: FXa mimetic binds SERPINC1:SERPINC1 activators (Homo sapiens)


name: EDNRA, EDNRB bind non-selective ERAs (Gallus gallus)


name: PLK1 phosphorylates FIRRM at S43 (Mus musculus)


name: (2E,6E)-farnesyl diphosphate <=> (1R,2R)-delta-elemene + diphosphate


name: PTGIS, CYP8A1 isomerise PGH2 to PGI2 (Danio rerio)


name: 1,2,3-tripropanoylglycerol + H2O <=> dipropanoylglycerol + propanoate + H(+)


name: LC3:ATG7 dimer binds ATG3 (Dictyostelium discoideum)


name: JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Canis familiaris)


name: 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(in) + ATP + H2O => 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine(out) + ADP + phosphate + H(+)


name: MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Xenopus tropicalis)


name: (9Z)-hexadecenoate + reduced [NADPH--hemoprotein reductase] + O2 <=> (9Z)-16-hydroxyhexadec-9-enoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a fatty acyl-[ACP] + a 1-acyl-sn-glycero-3-phosphate = a 1,2-diacyl-sn-glycero-3-phosphate + holo-[ACP]


name: positive regulation of transforming growth factor beta2 production


name: (S)-3-Hydroxyhexadecanoyl-CoA+NAD => 3-Oxopalmitoyl-CoA+NADH+H (Caenorhabditis elegans)


name: (E)-non-2-en-1-ol + NADP(+) = (E)-non-2-enal + NADPH + H(+)


name: propanoyl-CoA + L-methionine = N-propanoyl-L-methioninate + CoA + H(+)


name: N-terminal L-glutaminyl-[peptide] = N-terminal 5-oxo-L-prolyl-[peptide] + NH4(+)


name: an aliphatic sulfonate + 4 oxidized [4Fe-4S]-[ferredoxin] + 2 H2O = 4 reduced [4Fe-4S]-[ferredoxin] + a carboxylate + sulfite + 6 H(+)


name: (E,E)-piperate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+) => (E,E)-feruperate + reduced [NADPH--hemoprotein reductase] + O2


name: (S)-reticuline + O2 => (S)-scoulerine + H2O2 + H(+)


name: FLIP(L) and procaspase-8 form heterodimer in FasL/CD95 signaling (Canis familiaris)


name: factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Xenopus tropicalis)


name: DHFR dimer reduces FOLA to DHF (Sus scrofa)


name: STUB1 ubiquitinates RIPK3 at K55, K363 (Canis familiaris)


name: a D-alpha-amino acid + A + H2O <=> a 2-oxocarboxylate + AH2 + NH4(+)


name: sphinganine + hexadecanoate <=> N-hexadecanoylsphinganine + H2O


name: Dermatan sulfate can be further sulfated on position 2 of iduronate (Mus musculus)


name: 1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA => 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA


name: (S)-eriodictyol + S-adenosyl-L-methionine <=> (S)-homoeriodictyol + S-adenosyl-L-homocysteine + H(+)


name: PTPN11 binds p-Y759-IL6ST (Mus musculus)


name: (2E,15Z,18Z,21Z,24Z,27Z)-triacontahexaenoyl-CoA + NADPH + H(+) = (15Z,18Z,21Z,24Z,27Z)-triacontapentaenoyl-CoA + NADP(+)


name: hp-IRAK1,hp-IRAK4 bind Pellino1,2,3 (Sus scrofa)


name: (3S)-citramalate(in) + sulfate(out) <=> (3S)-citramalate(out) + sulfate(in)


name: CCNA:CDK1 phosphorylates HJURP (Sus scrofa)


name: Arachidonate is hydroxylated to 19-HETE by CYP(2) (Drosophila melanogaster)


name: UVSSA:USP7 deubiquitinates ERCC6 (Gallus gallus)


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Gallus gallus)


name: DNA polymerase delta polymerizes DNA across single stranded gap (Bos taurus)


name: Accessory proteins are recruited to the maturing virion (Homo sapiens)


name: Formation of p-STAT1 homodimer (Danio rerio)


name: (R)-acetoin + NAD(+) => diacetyl + NADH + H(+)


name: IDO2 dioxygenates L-Trp to NFK (Canis familiaris)


name: berkeleyone B + 2-oxoglutarate + O2 => berkeleydione + succinate + CO2 + H2O


name: 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+) => 1-(5-phospho-beta-D-ribosyl)-ATP + H2O


name: ATG10 transfers ATG12 from ATG7 to ATG10 (Homo sapiens)


name: thiosulfate(in) + sulfate(out) <=> thiosulfate(out) + sulfate(in)


name: Renin hydrolyzes Angiotensinogen to AGT(25-34) (Angiotensin-(1-10)) (Bos taurus)


name: gamma-terpinene + diphosphate => (2E)-geranyl diphosphate


name: (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O => (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate


name: itaconyl-CoA + succinate => itaconate + succinyl-CoA


name: PC carboxylates PYR to OA (Xenopus tropicalis)


name: With a quinone or similar compound as acceptor


name: L-tyrosine transmembrane transporter activity


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Sus scrofa)


name: biliverdin IXbeta + NADPH + H(+) => bilirubin IXbeta + NADP(+)


name: C-terminal Hh fragments are bound by lectins (Bos taurus)


name: ALDH4A1 converts 1PYR-3OH-5COOH to 4-OH-L-glutamate (Mus musculus)


name: nitrate(in) + nitrite(out) <=> nitrate(out) + nitrite(in)


name: 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Gallus gallus)


name: KDM6B demethylates H3K27me3 on p16INK4A promoter (Dictyostelium discoideum)


name: Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Gallus gallus)


name: AGK:Mg2+ phosphorylates MAG, DAG (Homo sapiens)


name: HATs and coactivators are recruited to the CTSD gene (Sus scrofa)


name: ATG5:ATG12 binds ATG16L2 (Xenopus tropicalis)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Homo sapiens)


name: PC is hydrolysed to 2-acyl LPC by PLA2[7] (Sus scrofa)


name: 7-dehydrocholesterol + NADPH + H(+) => cholesterol + NADP(+)


name: rRNA (uridine) methyltransferase activity


name: 7-O-methylvitexin 2''-O-beta-L-rhamnoside + S-adenosyl-L-homocysteine + H(+) => vitexin 2''-O-beta-L-rhamnoside + S-adenosyl-L-methionine


name: S-hexadecanoyl-L-cysteinyl-[protein] + H2O => L-cysteinyl-[protein] + hexadecanoate + H(+)


name: B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda (Mus musculus)


name: ALOX5 oxidises 17(R)-HDHA to 4(S)-Hp-17(R)-HDHA (Dictyostelium discoideum)


name: dehydroprobetaenone I + AH2 <=> probetaenone I + A


name: RAB3IP stimulates nucleotide exchange on RAB8A (Danio rerio)


name: UMP(out) + UDP-alpha-D-glucuronate(in) = UMP(in) + UDP-alpha-D-glucuronate(out)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + H2O => 1-octadecanoyl-sn-glycerol + (9Z,12Z)-octadecadienoate + H(+)


name: RHOQ positively regulates trafficking of GOPC:CFTR to the plasma membrane (Homo sapiens)


name: an N(5)-acyl-L-ornithine ester + H2O => an N(5)-acyl-L-ornithine + an alcohol + H(+)


name: methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside + H2O => methyl beta-D-galactoside + L-fucose


name: SPP1 (osteopontin) binds CD44 (Sus scrofa)


name: ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG (Canis familiaris)


name: arginine + H2O => ornithine + urea [ARG1] (Bos taurus)


name: (3R)-hydroxy-(15Z)-tetracosenoyl-CoA + NADP(+) => 3-oxo-(15Z)-tetracosenoyl-CoA + NADPH + H(+)


name: HTN1,HTN3 or HTN5 binds the bacterial anionic surface  (Bos taurus)


name: PTPN11 binds p-7Y-RUNX1 (Rattus norvegicus)


name: SEMA6D binds to PLXNA1:TREM2:DAP12 (Homo sapiens)


name: 5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al (Rattus norvegicus)


name: Aquaporins passively transport glycerol into cells (Bos taurus)


name: 4-epi-eremophilene-2beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 4-epi-eremophilene + reduced [NADPH--hemoprotein reductase] + O2


name: a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)


name: progesterone + reduced [NADPH--hemoprotein reductase] + O2 => 6beta-hydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Methylthio-ribulose-P => Methylthio-ribose-P (Homo sapiens)


name: 2 (2R)-bisdechlorogeodin + 2 H2O => 2 sulochrin + O2 + 2 H(+)


name: NME6 phosphorylates (d)NDPs to (d)NTPs (Homo sapiens)


name: ALOX5 dehydrogenates 7(S)-Hp-17(S)-HDHA to 7S(8)-epoxy-17S-HDHA (Xenopus tropicalis)


name: TP53 stimulates TIGAR expression (Homo sapiens)


name: L-tyrosyl-[protein] + ADP-D-ribose => O-(ADP-D-ribosyl)-L-tyrosyl-[protein] + H2O


name: FABP5 dissociates from RXRA:PPARD:atRA (Gallus gallus)


name: a ganglioside GM2 + H2O = a ganglioside GA2 + N-acetylneuraminate


name: PCho is dephosphorylated to Cho by PHOSPHO1 (Canis familiaris)


name: 6-hydroxynicotinate + O2 + H2O => 2,6-dihydroxynicotinate + H2O2


name: BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Mus musculus)


name: WNT5A binds FZD4 (Caenorhabditis elegans)


name: calcium-activated cation channel activity


name: TRPM4 transports Na+ from the extracellular region to the cytosol (Homo sapiens)


name: decanoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 10-hydroxydecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: PA is hydrolysed to 1-acyl LPA by PLA2G2A (Sus scrofa)


name: SMPD1 converts sphingomyelin to ceramide (Homo sapiens)


name: Persulfide sulfur is dioxygenated (Mus musculus)


name: N-acetylglycyl-tRNA(Gly) + H2O <=> N-acetylglycine + tRNA(Gly) + H(+)


name: MLPH/MYRIP bind GGC-RAB27A and MYO5A (Bos taurus)


name: N-(1-deoxy-beta-D-fructopyranos-1-yl)-L-phenylalanine + O2 + H2O => 2-dehydro-D-glucose + L-phenylalanine + H2O2


name: kojibiose + H2O = alpha-D-glucose + D-glucose


name: 4-sulfomuconolactone + H2O = maleylacetate + sulfite + 2 H(+)


name: 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + hexadecanoate + H(+) => 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + H2O


name: brain-derived neurotrophic factor receptor activity


name: motiol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 => 4beta-carboxyl motiol + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: (2E,6E)-farnesyl diphosphate => (1R,4R,5S)-(-)-guaia-6,10(14)-diene + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)


name: L-glycero-L-galacto-octuluronate-1-phosphate <=> aldehydo-L-arabinuronate + dihydroxyacetone phosphate


name: 8'-apo-beta-carotenol + O2 <=> 14'-apo-beta-carotenal + (3E,5E)-7-hydroxy-6-methylhepta-3,5-dienal


name: RHOA binds effectors at the plasma membrane (Schizosaccharomyces pombe)


name: CRY is phosphorylated by SGG (Drosophila melanogaster)


name: (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 => (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O


name: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + NADH + H(+)


name: Transfer of Ub from E2 to substrate and release of E2 (Sus scrofa)


name: SAMD8 transfers phosphatidyl from PE onto C16DH CER (Homo sapiens)


name: Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Mus musculus)


name: ABC-type phytochelatin transporter activity


name: PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Plasmodium falciparum)


name: thymidine(out) + Na(+)(out) = thymidine(in) + Na(+)(in)


name: Translocation of coproporphyrinogen III from the cytosol to the mitochondrial intermembrane space (Gallus gallus)


name: 4-hydroxyphenylacetate + FADH2 + O2 <=> 3,4-dihydroxyphenylacetate + FAD + H2O + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate = cycloaraneosene + diphosphate


name: FTMT 24mer oxidises 4Fe2+ to 4Fe(3+)O(OH) (Rattus norvegicus)


name: Nuclear translocation of p38 MAPK (Rattus norvegicus)


name: (2-methylphenoxy)acetate + 2-oxoglutarate + O2 <=> 2-hydroxytoluene + glyoxylate + succinate + CO2


name: N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2] + nicotinamide + H(+) => diphthamide-[translation elongation factor 2] + NAD(+)


name: SLC35B4 mediates the transport of UDP-N-acetylglucosamine into the Golgi lumen (Caenorhabditis elegans)


name: (2E)-docosenoyl-CoA + H2O => (3R)-hydroxydocosanoyl-CoA


name: a ganglioside GT1b (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate => a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)


name: Oligomerization of Bcl10 (Gallus gallus)


name: 13-cis-retinal + NADPH + H(+) => 13-cis-retinol + NADP(+)


name: ILK interacts with beta-1 integrin (Mus musculus)


name: Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol (Canis familiaris)


name: Inactive G alpha (12/13) reassociates with G beta:gamma (Canis familiaris)


name: UBIA1D prenylates menadione to form MK4 (vitamin K hydroquinone) (Mus musculus)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Xenopus tropicalis)


name: DPP4(39-766) hydrolyzes Glucagon-like Peptide-1 (GLP-1) (Canis familiaris)


name: carbovir monophosphate + ATP => carbovir diphosphate + ADP (Homo sapiens)


name: a 5'-end (5'-methylphospho)-ribonucleoside-RNA + S-adenosyl-L-methionine <=> a 5'-end (5'-bismethylphospho)-ribonucleoside-RNA + S-adenosyl-L-homocysteine


name: (E)-8-(methylsulfanyl)octanal oxime + CO2 + H2O => N,N-dihydroxy-L-pentahomomethionine + H(+)


name: xanthurenate + L-alanine + H2O => 3-hydroxy-L-kynurenine + pyruvate


name: 3-phenylpropanoate + ATP + NADPH + H(+) <=> 3-phenylpropanal + AMP + diphosphate + NADP(+)


name: (+)-kolavelool + S-adenosyl-L-methionine <=> (+)-O-methylkolavelool + S-adenosyl-L-homocysteine + H(+)


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Danio rerio)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O <=> 1D-myo-inositol 1-phosphate + a 1,2-diacyl-sn-glycerol + H(+)


name: a 2,3-saturated acyl-CoA + A <=> a 2,3-dehydroacyl-CoA + AH2


name: PI3P is dephosphorylated to PI by MTMR2:SBF1 (Dictyostelium discoideum)


name: Direct recruitment of PI3K to p-KIT (Homo sapiens)


name: (10Z,13Z,16Z,19Z)-docosatetraenoyl-CoA + malonyl-CoA + H(+) <=> 3-oxo-(12Z,15Z,18Z,21Z)-tetracosatetraenoyl-CoA + CO2 + CoA


name: phosphorylated GLI proteins bind SPOP:CUL3:RBX1 (Danio rerio)


name: 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + H2O = a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoate + H(+)


name: 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol <=> 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+)


name: IL4I1:FAD oxidises L-Phe to kPPV (Homo sapiens)


name: cya and lef bind to pagA(197-794):ANTXR1 oligomer (Homo sapiens)


name: DLST transfers succinyl to CoA (Danio rerio)


name: 5-dehydro-D-fructose + AH2 => keto-L-sorbose + A


name: ZnT8 transports zinc into the Golgi apparatus (Mus musculus)


name: D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate<=> xylulose 5-phosphate+ribose 5-phosphate  (Drosophila melanogaster)


name: (E)-anol + acetate + NADP(+) => (E)-coumaryl acetate + NADPH


name: deoxycholoyl-CoA + ursodeoxycholate => ursodeoxycholoyl-CoA + deoxycholate


name: 10-deoxysarpagine + reduced [NADPH--hemoprotein reductase] + O2 <=> sarpagine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 19beta-hydroxyisomotiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => isomotiol + reduced [NADPH--hemoprotein reductase] + O2


name: ATF2 acetylates histone H2B, H4 (Drosophila melanogaster)


name: Tropoelastin associates with microfibrils (Rattus norvegicus)


name: 12-hydroxyoctadecanoate + reduced [NADPH--hemoprotein reductase] + O2 => 12,18-dihydroxyoctadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: sphinga-4E,14Z-dienine + octadecanoyl-CoA => N-octadecanoyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: 2Fe-2S is inserted in UQCRFS1 (Homo sapiens)


name: L-lysyl-[alpha-tubulin] + acetate => N(6)-acetyl-L-lysyl-[alpha-tubulin] + H2O


name: Reduction of isocaproaldehyde to 4-methylpentan-1-ol (Dictyostelium discoideum)


name: p-CBL:GRB2 binds p-FRS2:activated FGFR1 (Sus scrofa)


name: p-T816-PKN2 phosphorylates AKT1 on serine-308 (Saccharomyces cerevisiae)


name: EXT1:EXT2 transfers GlcNAc to the heparan chain (Canis familiaris)


name: mogroside IV + UDP-alpha-D-glucose <=> mogroside V + UDP + H(+)


name: ent-copalyl diphosphate = ent-trachylobane + diphosphate


name: 3''-dehydroorientin => 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin


name: L-tyrosyl-[protein] + bromide + H2O2 + H(+) = 3-bromo-L-tyrosyl-[protein] + 2 H2O


name: Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Danio rerio)


name: MyD88 oligomerization within the complex of activated TLR:MyD88 (Homo sapiens)


name: negative regulation of nucleotide biosynthetic process


name: Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants (Homo sapiens)


name: Maturation of the canonical 20S core particle (Rattus norvegicus)


name: D-aspartate(in) + sulfate(out) <=> D-aspartate(out) + sulfate(in)


name: propanoate + ATP + CoA <=> propanoyl-CoA + ADP + phosphate


name: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine


name: an N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-N-acetyl-beta-D-muramyl derivative + H2O = an N-acetyl-beta-D-glucosaminyl-(1->4)-1,6-anhydro-beta-D-muramyl derivative + acetate


name: brassicasterol + UDP-alpha-D-glucose => brassicasterol 3-beta-D-glucoside + UDP + H(+)


name: Relaxin receptor 2 binds relaxin 2 and INSL3 (Danio rerio)


name: Ubiquitinated Orc1 enters the cytosol (Caenorhabditis elegans)


name: p-PKR dimer phosphorylates MKK6 (Danio rerio)


name: GDIs block activation of RHOG (Danio rerio)


name: Collagen type VII binds integrin alpha2beta1 (Rattus norvegicus)


name: PSMD9 binds PSMC3:PSMC6 (Drosophila melanogaster)


name: I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol (Danio rerio)


name: MSRA reduces L-methyl-(S)-S-oxide to L-Methionine (Sus scrofa)


name: Activation of proMMP8 (Canis familiaris)


name: N(2)-acetyl-L-ornithine + carbamoyl phosphate => N(2)-acetyl-L-citrulline + phosphate + H(+)


name: beta-hydroxyisobutyryl-CoA + H2O => beta-hydroxyisobutyrate + CoA (Bos taurus)


name: Interaction of PIN1 with p-IRF3 (Mus musculus)


name: 4-hydroxyeicosasphinganine 1-phosphate <=> 2-hydroxyoctadecanal + phosphoethanolamine


name: 2 reduced [cytochrome P450] + NAD(+) + H(+) => 2 oxidized [cytochrome P450] + NADH