name: [(3R)-hydroxybutanoate](n) + H2O <=> [(3R)-hydroxybutanoate](n-4) + (3R)-hydroxybutanoate tetramer + H(+)


name: TP53I3 oxidoreductase generates unstable semiquinones (Homo sapiens)


name: IDUA hydrolyses the unsulfated alpha-L-iduronosidic link in DS (Xenopus tropicalis)


name: N-terminal L-cysteinyl-[protein] + hexadecanoyl-CoA => N-terminal N-hexadecanoyl-L-cysteinyl-[protein] + CoA + H(+)


name: (-)-dehydrodiconiferyl acid carboxylate + a quinol + H(+) => (-)-dehydrodiconiferyl acid ketone + a quinone + H2O


name: hexadecanoyl-AMP + diphosphate => hexadecanoate + ATP + H(+)


name: (2E)-decenal + NADPH + H(+) => decanal + NADP(+)


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 <=> (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate


name: RHOU binds effectors at the plasma membrane (Drosophila melanogaster)


name: Interaction of Afadin with F-actin (Homo sapiens)


name: p-T68-CHEK2 dimerizes (Xenopus tropicalis)


name: deoxycholate + NAD(+) => 12alpha-hydroxy-3-oxo-5beta-cholan-24-oate + NADH + H(+)


name: a (2E)-enoyl-CoA + NADPH + H(+) <=> a 2,3-saturated acyl-CoA + NADP(+)


name: IL21 receptor JAK phosphorylation (Rattus norvegicus)


name: (6R)-5,10-methenyltetrahydrofolate + NADH => (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NAD(+)


name: (2R,4S)-ketoconazole(in) + ATP + H2O = (2R,4S)-ketoconazole(out) + ADP + phosphate + H(+)


name: 2 dimethylallyl diphosphate <=> (R)-lavandulyl diphosphate + diphosphate


name: 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoate + H(+) => 5,7-dihydroxy-4-methylphthalide + H2O


name: RUNX2 and SMAD1 complex binds the SMAD6 gene promoter (Homo sapiens)


name: IC-asc-C7-CoA + AMP + diphosphate => IC-asc-C7 + ATP + CoA


name: 2 H2 + 2 oxidized [2Fe-2S]-[ferredoxin] + NAD(+) => 2 reduced [2Fe-2S]-[ferredoxin] + NADH + 3 H(+)


name: PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Homo sapiens)


name: minus-end-directed microtubule motor activity


name: SPT5 subunit of Pol II binds the RNA triphosphatase (RTP) (Xenopus tropicalis)


name: silicate transmembrane transporter activity


name: ADP-alpha-D-glucose + D-glucose 6-phosphate = alpha,alpha-trehalose 6-phosphate + ADP + H(+)


name: Tenascins C, R, (X, N) bind fibronectin matrix (Danio rerio)


name: PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Homo sapiens)


name: PQLC2 transports L-Arg,L-His,L-Lys from lysosomal lumen to cytosol (Bos taurus)


name: ganglioside GT1b (d18:1(4E)/18:0) + H2O <=> ganglioside GD1b(d18:1(4E)/18:0) + N-acetylneuraminate


name: all-trans-zeaxanthin + O2 = (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal


name: tyrosine phosphorylation of Stat4 protein


name: GSK3B phosphorylates p-NFE2L2 (Rattus norvegicus)


name: inhibition of maltoheptaose metabolic process


name: Protein 3a forms a homotetramer (Homo sapiens)


name: EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Sus scrofa)


name: 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP => 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(out) + ADP + phosphate + H(+) => 7-O-[2-aminoethoxy(hydroxy)phosphoryl]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A(in) + ATP + H2O


name: N-acetyl-alpha-D-galactosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + GDP-alpha-D-mannose = alpha-D-mannosyl-(1->3)-N-acetyl-alpha-D-galctosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + GDP + H(+)


name: gibberellin A19 + 2-oxoglutarate + O2 = gibberellin A17 + succinate + CO2 + H(+)


name: spermidine + CO2 => carboxyspermidine + H(+)


name: dehydroepiandrosterone (DHEA) + PAPS => DHEA sulfate + PAP (Mus musculus)


name: ATG10 transfers ATG12 from ATG10 to ATG5 (Canis familiaris)


name: Defective BRCA2 does not translocate to the nucleus (Homo sapiens)


name: (3S)-3-aminobutanoyl-CoA + acetoacetate => (5S)-5-amino-3-oxohexanoate + acetyl-CoA


name: Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Danio rerio)


name: activation of apolipoprotein A-I-mediated signaling pathway


name: N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) + 3 H(+)(in) => N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) + 3 H(+)(out)


name: carbamoyl phosphate + ADP + H2O + H(+) => hydrogencarbonate + NH4(+) + ATP


name: IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)


name: EDTA + FMNH2 + O2 = ethylenediaminetriacetate + FMN + glyoxylate + H2O + 2 H(+)


name: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + reduced [NADPH--hemoprotein reductase] + O2 => N-(20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphing-4-enine + UDP + H(+) => a N-(2-hydroxyacyl)sphing-4-enine + UDP-alpha-D-galactose


name: IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Rattus norvegicus)


name: [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl-5-semialdehyde)-L-glutamate + phosphate + NADP(+) <=> [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + NADPH + H(+)


name: PTP-RO interacts with p-c-Kit complex (Sus scrofa)


name: (6E)-8-oxogeranial + NADH + H(+) => (6E)-8-hydroxygeranial + NAD(+)


name: NLRP4 and DTX4 associate with p-S172-TBK1 within STING:TBK1:IRF3 (Rattus norvegicus)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 = 13-hydroxy-(9Z,11E)-octadecadienoate + A + H2O


name: EGR-dependent NAB2 gene expression (Homo sapiens)


name: a ganglioside GD1a + acetyl-CoA <=> a ganglioside Ac-O-7-GD1a + CoA


name: UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate + ATP + H2O <=> UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + AMP + diphosphate + H(+)


name: METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1 (Mus musculus)


name: 2 9,10-phenanthrosemiquinone + NADP(+) => 2 9,10-phenanthroquinone + NADPH + H(+)


name: unsaturated fatty acid biosynthetic process


name: guanosine(26)/guanosine(27) in tRNA + 4 S-adenosyl-L-methionine <=> N(2)-dimethylguanosine(26)/N(2)-dimethylguanosine(27) in tRNA + 4 S-adenosyl-L-homocysteine + 4 H(+)


name: PDE3B hydrolyses cAMP to AMP (Saccharomyces cerevisiae)


name: guanosine(748) in 23S rRNA + S-adenosyl-L-methionine => N(1)-methylguanosine(748) in 23S rRNA + S-adenosyl-L-homocysteine + H(+)


name: GPR143 binds L-Dopa (Xenopus tropicalis)


name: Phosphorylation of PLC-gamma by p-BTK/p-SYK (Gallus gallus)


name: 2-deoxy-D-glucose 6-phosphate + NAD(+) => 2-deoxy-6-phospho-D-glucono-1,5-lactone + NADH + H(+)


name: ubiquinol-8(in) + nitrate(out) = ubiquinone-8(in) + nitrite(out) + H2O(out)


name: SMG6 hydrolyzes mRNA with premature termination codon (Drosophila melanogaster)


name: Translocation of RIAM to plasma membrane (Drosophila melanogaster)


name: 3-dehydro-2,22-dideoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H(+) => 3-dehydro-2-deoxyecdysone + 2 oxidized [adrenodoxin] + H2O


name: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + 4 AH2 => sn-3-O-phytanylglycerol 1-phosphate + 4 A


name: ilicicolin A epoxide + NADPH + O2 + H(+) => 16-hydroxy-ilicicolin A epoxide + NADP(+) + H2O


name: tetradecan-1-ol + NADP(+) <=> tetradecanal + NADPH + H(+)


name: Thrombin, ELANE cleave C5 (Gallus gallus)


name: 5-hydroxyindole acetaldehyde to 5-hydroxyindole acetic acid (Danio rerio)


name: D-glucosamine 6-phosphate + NADP(+) <=> 2-amino-2-deoxy-6-phospho-D-glucono-1,5-lactone + NADPH + 2 H(+)


name: (+)-artemisinic aldehyde + NADP(+) + H2O => (+)-artemisinate + NADPH + 2 H(+)


name: inhibition of antigen receptor-mediated signaling pathway


name: eIF3 and eIF1A bind to the 40S subunit (Rattus norvegicus)


name: 2alpha,19beta-dihydroxyisomotiol + reduced [NADPH--hemoprotein reductase] + O2 => 2alpha-hydroxyismotiol-19-one + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: 1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + H2O = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + (9Z)-octadecenoate + H(+)


name: Activated FGFR1:p-FRS phosphorylates PPTN11 (Drosophila melanogaster)


name: LC3 is cleaved by ATG4 (Plasmodium falciparum)


name: an N-alkylglycine + O2 + H2O => an alkylamine + glyoxylate + H2O2


name: Activation of GIRK/Kir3 Channels (Mus musculus)


name: 3-methylbenzyl alcohol + O2 => 3-methylbenzaldehyde + H2O2


name: inhibition of beta-D-lactosidase activity


name: MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) (Dictyostelium discoideum)


name: pyridoxine(out) + n H(+)(out) = pyridoxine(in) + n H(+)(in)


name: L-alanine(in) + H(+)(in) => L-alanine(out) + H(+)(out)


name: an alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-alpha-D-GalNAc derivative + UDP-alpha-D-galactose <=> an alpha-D-Gal-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->3)-alpha-D-GalNAc derivative + UDP + H(+)


name: D-ribose + NADP(+) + H2O = D-ribonate + NADPH + 2 H(+)


name: 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + CoA


name: (3R)-hydroxytetradecanoyl-CoA + NAD(+) => 3-oxotetradecanoyl-CoA + NADH + H(+)


name: glycerol + hexadecanoate + H(+) => 1-hexadecanoylglycerol + H2O


name: 1-octadecanoyl-sn-glycero-3-phosphate + CoA => sn-glycerol 3-phosphate + octadecanoyl-CoA


name: Methylthio-ribulose-P => Methylthio-ribose-P (Canis familiaris)


name: ACE:Zn2+ hydrolyzes AGT(25-33) (Angiotensin-(1-9)) to AGT(25-31) (Angiotensin-(1-7)) (Gallus gallus)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Bos taurus)


name: PLPP1 dephosphorylates extracellular sphingosine-1-phosphate (Schizosaccharomyces pombe)


name: 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-formyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + H(+)


name: fraxetin + reduced [NADPH--hemoprotein reductase] + O2 = sideretin (reduced form) + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: VLDLR:PCSK9 binds Clathrin-coated vesicles (Gallus gallus)


name: CORIN(802-1042) hydrolyses NPPA to form NPPA(124-151) (Homo sapiens)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Caenorhabditis elegans)


name: P2X7 mediates membrane pores that include pannexin-1 (Sus scrofa)


name: PC is hydrolyzed to 1-acyl LPC by PLB1 (Sus scrofa)


name: phenylacetyl-CoA + H2O = 2-phenylacetate + CoA + H(+)


name: methotrexate(in) + H(+)(in) <=> methotrexate(out) + H(+)(out)


name: p130Cas and C3G bind PDGFR bound Crk (Mus musculus)


name: fumigatonoid C + 2-oxoglutarate + O2 => novofumigatonin + succinate + CO2 + H2O


name: 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(in) + ATP + H2O = 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine(out) + ADP + phosphate + H(+)


name: 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + H2O => 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoate + H(+)


name: LTA4 is converted to EXA4 by ALOX15 (Sus scrofa)


name: tyramine + S-adenosyl-L-methionine <=> N-methyltyramine + S-adenosyl-L-homocysteine + H(+)


name: N6AMT1:TRMT112 transfers CH3 group from AdoMet to MMAIII (Dictyostelium discoideum)


name: GMDS dehydrates GDP-Man to GDP-DHDMan (Bos taurus)


name: 6alpha-hydroxy-28-nortyphasterol + reduced [NADPH--hemoprotein reductase] + O2 = 28-nortyphasterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: but-3-ynal + pyrroloquinoline quinol + H(+) = but-3-yn-1-ol + pyrroloquinoline quinone


name: O-phospho-L-seryl-[receptor-protein] + ADP + H(+) => L-seryl-[receptor-protein] + ATP


name: EPHX2 dimer hydrolyses 13(S),14(S)-epoxy-DHA to MaR2 (Rattus norvegicus)


name: nitrite(in) + H(+)(out) <=> nitrite(out) + H(+)(in)


name: PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Dictyostelium discoideum)


name: indole-3-acetyl-1D-myo-inositol + UDP-alpha-D-galactose => 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + UDP + H(+)


name: protein tyrosine kinase inhibitor activity


name: botE LC cleaves target cell SNAP25 (Homo sapiens)


name: 3-dehydro-L-gulonate + NAD(+) <=> 2,3-dioxo-L-gulonate + NADH + H(+)


name: PIAS1 SUMOylates L3MBTL2 with SUMO2 (Rattus norvegicus)


name: (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate <=> sulforaphane + sulfate


name: Disassociation of CLIP from MHC II (Mus musculus)


name: 3-aminobutan-2-ol + NADP(+) + H2O <=> acetoin + NH4(+) + NADPH + H(+)


name: 10 malonyl-CoA + acetyl-CoA + 3 AH2 + 8 NADPH + 18 H(+) = cordypyrone A + 3 A + 10 CO2 + 8 NADP(+) + 11 CoA + 8 H2O


name: PIAS1 SUMOylates SP3 with SUMO1 (Danio rerio)


name: Arachidonate  is converted to 12-oxoETE by ALOX12 (Bos taurus)


name: SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (Caenorhabditis elegans)


name: 6-methylpretetramide + NADPH + O2 + 2 H(+) => 4-hydroxy-6-methylpretetramide + NADP(+) + H2O


name: NADPH oxidase 2 (NOX2) complex binds RAC1 (Mus musculus)


name: [LarE protein]-S-[1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridinium-3-carbonyl]-L-cysteine = pyridinium-3,5-bisthiocarboxylate mononucleotide + [LarE protein]-dehydroalanine + H(+)


name: eicosanoyl-CoA + 2 NADPH + 2 H(+) => eicosan-1-ol + 2 NADP(+) + CoA


name: RAD52 promotes single strand annealing at resected DNA DSBs (Gallus gallus)


name: histone H4K12 deacetylase activity, hydrolytic mechanism


name: 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine => 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol


name: 4-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholesten-7alpha, 12alpha-diol-3-one (Xenopus tropicalis)


name: Fe(III)-enterobactin(out) + ATP + H2O => Fe(III)-enterobactin(in) + ADP + phosphate + H(+)


name: (R)-dihydrolipoamide + acetyl-CoA = (R)-S(6)-acetyldihydrolipoamide + CoA


name: (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + malonyl-CoA + H(+) <=> 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA


name: regulation of butyryl-CoA catabolic process to butyrate


name: 1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG (Homo sapiens)


name: 2 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) = 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(3'-(9Z-octadecenoyl)-1'-sn-glycerol) + sn-glycero-3-phospho-(1'-sn-glycerol)


name: AKT phosphorylates FOXO3 downstream of FLT3  (Homo sapiens)


name: L-asparagine + H2O => L-aspartate + NH4(+)


name: E-cadherin degradation by MMP9, KLK7 (Bos taurus)


name: LPA-binding receptors bind LPA (Mus musculus)


name: CFTR transits to the plasma membrane (Plasmodium falciparum)


name: 2-methylhexanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> 2-methylhexenoyl-CoA + reduced [electron-transfer flavoprotein]


name: PDGF dimer binds two receptors simultaneously (Canis familiaris)


name: PEX19 binds class I peroxisomal membrane proteins (Sus scrofa)


name: 3-demethylubiquinol-9 + S-adenosyl-L-methionine <=> ubiquinol-9 + S-adenosyl-L-homocysteine + H(+)


name: ZFPM proteins bind GATA proteins (Bos taurus)


name: PE is converted to PS by PTDSS2 (Xenopus tropicalis)


name: (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADPH + H(+) <=> (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + NADP(+)


name: cAMP binds PKA tetramer (Schizosaccharomyces pombe)


name: 4-methyl-3-oxopentanoyl-[ACP] + NADPH + H(+) => (3R)-hydroxy-4-methylpentanoyl-[ACP] + NADP(+)


name: 4-nitrophenyl-3-ketovalidamine = 5D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + 4-nitroaniline


name: palmitoyl-CoA + DHAP => 1-palmitoylglycerone phosphate + CoASH (Xenopus tropicalis)


name: cholate(in) + glutathione(in) + ATP + H2O <=> cholate(out) + glutathione(out) + ADP + phosphate + H(+)


name: isopimara-7,15-diene + diphosphate => (+)-copalyl diphosphate


name: DLST transfers succinyl to CoA (Xenopus tropicalis)


name: Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Danio rerio)


name: RhoA is activated by nucleotide exchange and inhibits axonal growth (Sus scrofa)


name: demethylsuberosin + reduced [NADPH--hemoprotein reductase] + O2 <=> (7S)-marmesin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Disassembly of SR-BI-bound spherical HDL (Bos taurus)


name: PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)


name: RNA polymerase III general transcription initiation factor activity


name: Active MTORC1 binds the ULK1 complex (Homo sapiens)


name: inosine + O2 => 9-riburonosylhypoxanthine + H2O + H(+)


name: UTP + D-glucose 1-phosphate => pyrophosphate + UDP-glucose (Canis familiaris)


name: (R)-2-hydroxyglutaryl-CoA => (2E)-glutaconyl-CoA + H2O


name: (d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Drosophila melanogaster)


name: Envoplakin binds periplakin (Canis familiaris)


name: 4-chlorosalicylate + NADH + O2 + 2 H(+) => 4-chlorocatechol + CO2 + NAD(+) + H2O


name: TWNK (PEO1) unwinds double-stranded mitochondrial DNA at the replication fork (Canis familiaris)


name: RIPK3 phosphorylates MLKL (Homo sapiens)


name: CA4:Zn2+ dehydrates HCO3- to CO2 (Mus musculus)


name: Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Saccharomyces cerevisiae)


name: DHODH:FMN binds DHODH inhibitors (Bos taurus)


name: Kazrin binds periplakin (Xenopus tropicalis)


name: Latent TGF-beta-3 binds integrins (Drosophila melanogaster)


name: Deamination at C6 position of adenosine in Editosome (ADAR1) (Sus scrofa)


name: N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = N-hexadecanoylethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H(+)


name: 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+) => 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O2


name: ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Gallus gallus)


name: Stalling of DNA replication fork and RPA binding (Canis familiaris)


name: N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)


name: Beta-catenin recruits CBP/p300 (Xenopus tropicalis)


name: L-homoseryl-tRNA(Lys) + H2O => tRNA(Lys) + L-homoserine + H(+)


name: 2,3-epoxy-2,3-dihydrobenzoyl-CoA + 2 H2O <=> (3Z)-6-oxohex-3-enoyl-CoA + formate + H(+)


name: (2E,4E)-decadienoyl-CoA + NADPH + H(+) => (2E)-decenoyl-CoA + NADP(+)


name: Bile salts and acids dissociate from ALB (Rattus norvegicus)


name: Binding of acetylcholine to highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)


name: BRAP autoubiquitinates (Xenopus tropicalis)


name: NPC exports GCK1 from nucleus (Plasmodium falciparum)


name: PXLP-KYAT1 dimer transaminates L-KYN to KYNA (Dictyostelium discoideum)


name: ERBB2 promotes PTK6 autophosphorylation (Sus scrofa)


name: PLK1 phosphorylates FIRMM at S744 (Sus scrofa)


name: O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate


name: propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Rattus norvegicus)


name: GDP-alpha-D-mannose + H2O <=> D-mannose + GDP + H(+)


name: Activated AKT phosphorylates RUNX2 (Homo sapiens)


name: RAC1 GDIs block activation of RAC1 (Saccharomyces cerevisiae)


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphate + ethanolamine + H(+)


name: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H2O <=> 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+)


name: XRCC4:LIG4, NHEJ1 and POLL or POLM bind DNA DSBs in NHEJ (Danio rerio)


name: TIMM21 carries COX4, COX5A, COX6C to MT-CO1:MITRAC (Bos taurus)


name: malonyl-[ACP] + acetate => acetyl-[ACP] + malonate


name: Dopamine synaptic vesicle docking and priming (Rattus norvegicus)


name: (3S)-hydroxy-(11Z)-docosenoyl-CoA => (2E,11Z)-docosadienoyl-CoA + H2O


name: a ganglioside GT3 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GT2 + UDP + H(+)


name: GLUT1 tetramer binds 4xATP (Rattus norvegicus)


name: 3'-phosphoadenylyl sulfate(out) + adenosine 3',5'-bisphosphate(in) => 3'-phosphoadenylyl sulfate(in) + adenosine 3',5'-bisphosphate(out)


name: CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Bos taurus)


name: 1-O-hexadecyl-2-succinyl-sn-glycero-3-phosphocholine + H2O <=> 1-O-hexadecyl-sn-glycero-3-phosphocholine + succinate + H(+)


name: SARDH:FAD oxidatively demethylates SARC to Gly (Rattus norvegicus)


name: (2E,7Z)-hexadecadienoyl-CoA + H2O => (3R)-hydroxy-(7Z)-hexadecenoyl-CoA


name: PIAS1 SUMOylates SAFB with SUMO2,3 (Sus scrofa)


name: N-(2-hydroxyhexadecanoyl)-sphinganine + CoA + H(+) => 2-hydroxyhexadecanoyl-CoA + sphinganine


name: beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer + GDP + H(+) => a neolactoside nLc6Cer + GDP-beta-L-fucose


name: PIN1 binds phosphorylated PIP4K2B (Gallus gallus)


name: polyporic acid + 2 AMP + 2 diphosphate + H(+) => 2 3-phenylpyruvate + 2 ATP


name: TRPV4 tetramer binds CALM1:Ca2+ (calmodulin:Ca2+) (Homo sapiens)


name: ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Homo sapiens)


name: (2E)-octenedioyl-CoA + H2O2 => octanedioyl-CoA + O2


name: Synthesis of SARS-CoV-1 minus strand subgenomic mRNAs by template switching (Homo sapiens)


name: UVSSA:USP7 deubiquitinates ERCC6 (Canis familiaris)


name: 2,4,6-trinitrotoluene + 2 NADPH + 2 H(+) => 4-hydroxylamino-2,6-dinitrotoluene + 2 NADP(+) + H2O


name: AP-2 (TFAP2) transcription factors form homo- and heterodimers (Canis familiaris)


name: Transactivation of PMAIP1 (NOXA) by E2F1 (Homo sapiens)


name: (3S)-hydroxydecanoyl-CoA = (2E)-decenoyl-CoA + H2O


name: 5beta-pregnan-3,20-dione + NADPH + H(+) => 20alpha-hydroxy-5beta-pregnan-3-one + NADP(+)


name: (E)-coniferol + A = (E)-coniferaldehyde + AH2


name: N-methyl-4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-methionine <=> N-methylmescaline + S-adenosyl-L-homocysteine + H(+)


name: CD22 binds itself to form homo-oligomers (Rattus norvegicus)


name: L-cysteine(out) + Na(+)(out) + H(+)(in) = L-cysteine(in) + Na(+)(in) + H(+)(out)


name: GCL ligates L-Glu to L-Cys (Drosophila melanogaster)


name: L-cystine + O2 + H2O => (2R)-2-amino-2-carboxylatoethyl-disulfanyl-oxopropanoate + H2O2 + NH4(+)


name: DECR2 reduces a (2E,4E)-dienoyl-CoA to a 4,5-saturated-(3E)-enoyl-CoA  (Bos taurus)


name: negative regulation of protein modification by small protein conjugation or removal


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Xenopus tropicalis)


name: Cyclin E:CDK2-mediated phosphorylation of RB1 (Canis familiaris)


name: CLPXP binds mitochondrial matrix proteins (Bos taurus)


name: uridine(32) in tRNA = pseudouridine(32) in tRNA


name: Meglitinides bind ABCC8 (Drosophila melanogaster)


name: L-glutamyl-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+) => gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate + ATP


name: 2 N(omega)-hydroxy-L-arginine + NADH + 2 O2 <=> 2 L-citrulline + 2 nitric oxide + NAD(+) + 2 H2O + H(+)


name: abieta-7,13-dien-18-ol + reduced [NADPH--hemoprotein reductase] + O2 => abieta-7,13-dien-18,18-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Beta-catenin enhances association of IRF3 with CBP/p300  (Rattus norvegicus)


name: (15Z)-tetracosenoyl-CoA + O2 => (2E,15Z)-tetracosadienoyl-CoA + H2O2


name: D-xylotriono-1,5-lactone + H2O <=> D-xylotrionate + H(+)


name: Bitter compound binds bitter taste receptor (TAS2R) (Danio rerio)


name: an N-acyl-15-methylhexadecasphing-4-enine-1-phosphocholine + a 1,2-diacyl-sn-glycerol => an N-acyl-15-methylhexadecasphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: SLC2A9 transports Fru, Glc, urate (Saccharomyces cerevisiae)


name: a cytidine in mRNA + formaldehyde + succinate + CO2 => an N(3)-methylcytidine in mRNA + 2-oxoglutarate + O2


name: AFG3L2 binds mitochondrial matrix proteins (Homo sapiens)


name: rebaudioside A + UDP-alpha-D-glucose <=> rebaudioside D + UDP + H(+)


name: (2E,6E,10E)-geranylgeranyl diphosphate + H2O = (6E,10E)-geranyllinalool + diphosphate


name: Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Bos taurus)


name: chlorothalonil + H2O <=> 4-hydroxychlorothalonil + chloride + 2 H(+)


name: 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + ATP + CoA <=> 8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoyl-CoA + AMP + diphosphate


name: NIK autophosphorylates on T559 (Danio rerio)


name: spermidine:coumaroyl CoA N-acyltransferase activity


name: Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Canis familiaris)


name: a 5'-end diphospho-guanosine in mRNA + N(epsilon)-GMP-L-lysyl-[protein] + 2 H(+) => a 5'-end (5'-triphosphoguanosine)-guanosine in mRNA + L-lysyl-[protein]


name: RNASEs bind bacterial phospholipids (Mus musculus)


name: N(alpha),N(alpha)-dimethyl-L-tryptophan + S-adenosyl-L-methionine <=> N(alpha),N(alpha),N(alpha)-trimethyl-L-tryptophan + S-adenosyl-L-homocysteine + H(+)


name: MRN complex binds DNA double strand breaks (Rattus norvegicus)


name: epothilone D + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => epothilone B + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: RNA Pol II initiates transcription from damaged DNA template (Schizosaccharomyces pombe)


name: Branching and elongation of mother and daughter filaments (Drosophila melanogaster)


name: an N(2)-(1-hydroxy-2-oxopropyl)-guanosine in RNA + H2O => a guanosine in RNA + lactate + H(+)


name: DPF1,2,3 binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1 (Sus scrofa)


name: 7-chlorotetracycline + FAD + 2 H2O + H(+) => tetracycline + FADH2 + chloride + O2


name: ADAMTS13 variant does not cleave VWF multimer (Homo sapiens)


name: IMP + L-Aspartate + GTP => Adenylosuccinate + GDP + Pi [ADSS] (Canis familiaris)


name: (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[protein] + H2O = (L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[protein] + L-glutamate


name: SLC8A1,2,3 exchange 3Na+ for Ca2+ (Gallus gallus)


name: L-aspartate 4-semialdehyde + propane-1,3-diamine + NADPH + H(+) => carboxynorspermidine + NADP(+) + H2O


name: AFG3L2 binds mitochondrial inner membrane proteins (Gallus gallus)


name: Insertion of correct bases opposite the lesion by POLH (Gallus gallus)


name: Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Mus musculus)


name: 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + GTP + H(+) => guanylylpyridinol + diphosphate


name: aralkylamine dehydrogenase (azurin) activity


name: NDST1-4 N-deacetylates GlcNAc residues in heparan (Caenorhabditis elegans)


name: PTGS2 dimer binds PTGS2 inhibitors (Danio rerio)


name: L-prolyl-[hypoxia-inducible factor alpha subunit] + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-prolyl-[hypoxia-inducible factor alpha subunit] + succinate + CO2


name: (9Z)-tetradecenoate + CoA + H(+) => (9Z)-tetradecenoyl-CoA + H2O


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Rattus norvegicus)


name: (2E)-hexadecenoyl-CoA + NADPH + H(+) => hexadecanoyl-CoA + NADP(+)


name: CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex (Bos taurus)


name: MADCAM1-1 binds Integrin alpha4beta7 (Mus musculus)


name: DSE converts GlcA to IdoA (Rattus norvegicus)


name: CGRP receptor can bind calcitonin gene-related peptides (Canis familiaris)


name: Fusion of late-endosome derived vesicles at the TGN (Homo sapiens)


name: AMT transfers NH2CH2 from GCSH:SAMDLL to THF (Caenorhabditis elegans)


name: Removal of fibrillar collagen N-propeptides (Sus scrofa)


name: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> a (9Z,11E,13Z)-octadeca-9,11,13-trienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: an (S)-2-haloacid + H2O <=> a (2S)-2-hydroxycarboxylate + a halide anion + H(+)


name: CSNK2-mediated phosphorylation of DVL (Drosophila melanogaster)


name: RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Gallus gallus)


name: Palmostatin B binds RAS depalmitoylases (Homo sapiens)


name: CYP2E1 monooxygenates APAP to NAPQI (Danio rerio)


name: tRNA(Lys) + L-homoserine + H(+) => L-homoseryl-tRNA(Lys) + H2O


name: DARC  is a non-specific receptor for many chemokines (Canis familiaris)


name: WLS binds WNT ligands in the Golgi (Bos taurus)


name: L-arabinitol + NADP(+) <=> L-arabinose + NADPH + H(+)


name: 1,2-ditetradecanoyl-sn-glycerol + ATP <=> 1,2-ditetradecanoyl-sn-glycero-3-phosphate + ADP + H(+)


name: TM7SF2 reduces 4,4-diMeCholesta-8,14-dien-3-ol to 4,4-diMe5-cholest-8-en-3-ol (Canis familiaris)


name: 5-methylsulfanyl-2,3-dioxopentyl phosphate = 2-hydroxy-5-methylsulfanyl-3-oxopent-1-enyl phosphate


name: p-Y705, S727 STAT3 dimer binds HIF1A gene (Homo sapiens)


name: (2E,5Z)-tetradecadienoyl-CoA + H2O => (3S)-hydroxy-(5Z-tetradecenoyl)-CoA


name: GTP + diphosphate + H(+) => guanosine 3'-diphosphate 5'-triphosphate + H2O


name: thrombin:antithrombin III:heparan sulfate -> thrombin:cleaved antithrombin III:heparan sulfate (Gallus gallus)


name: cholesterol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> a cholesterol ester + a 1-acyl-sn-glycero-3-phosphocholine


name: Expression of ESRRA (ERR1, ERRalpha) (Homo sapiens)


name: nitrate + a quinol => a quinone + nitrite + H2O


name: 2-oxo-3-sulfanylpropanoate + L-cysteinyl-[protein] <=> S-sulfanyl-L-cysteinyl-[protein] + pyruvate


name: SPAM1 randomly cleaves HA (Canis familiaris)


name: TRAIL binds TRAIL receptors (Danio rerio)


name: a nucleoside + phosphate => a nucleoside 5'-phosphate + H2O


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-octadecanoyl-sn-glycero-3-phosphocholine


name: Activated protein C:PROCR binds F2R (Gallus gallus)


name: Ubiquitinated TP53 translocates to the cytosol (Sus scrofa)


name: IP6 is dephosphorylated to I(1,2,4,5,6)P5 by MINPP1 in the ER lumen (Mus musculus)


name: NADH dehydrogenase (ubiquinone) (non-electrogenic) activity


name: a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)


name: SLC4A1 exchanges cytosolic Cl- for extracellular HCO3- (Drosophila melanogaster)


name: a ganglioside SM1a + 3'-phosphoadenylyl sulfate = a ganglioside SB1a + adenosine 3',5'-bisphosphate + H(+)


name: alpha,alpha-trehalose + H2O <=> alpha-D-glucose + beta-D-glucose


name: 9-hydroxy-octadecanoate + a triacylglycerol => 9-(acyloxy)-octadecanoate + a 2,3-diacyl-sn-glycerol


name: K(+)(in) + L-cysteine(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-cysteine(in) + 3 Na(+)(in) + H(+)(in)


name: a 3'-end ribonucleotide-RNA + a ribonucleoside 5'-phosphate + H(+) => a 3'-end ribonucleotidyl-ribonucleotide-RNA + H2O


name: (3S)-citramalyl-CoA => 3-methylfumaryl-CoA + H2O


name: Autophosphorylation of PDGF alpha/beta receptors (Mus musculus)


name: HRH1 binds HRH1 inverse agonists (Canis familiaris)


name: (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+) <=> 3-methylcatechol + NADH + H(+)


name: EGFR activates PLC-gamma1 by phosphorylation (Sus scrofa)


name: Bruton's Tyrosine Kinase Inhibitors [MoA]


name: 2 (4Z,15Z)-bilirubin IXalpha + O2 => 2 biliverdin IXalpha + 2 H2O


name: positive regulation of non-canonical Wnt signaling pathway


name: chenodeoxycholate + NAD(+) => 3-oxochenodeoxycholate + NADH + H(+)


name: ACAT1 tetramer acetylates IDH2 dimer (Sus scrofa)


name: (indol-3-yl)acetyl-CoA + AMP + H(+) => (indol-3-yl)acetyl-AMP + CoA


name: Nuclear DUSPs dephosphorylate MAPKs (Danio rerio)


name: I(1,4,5)P3 transports from the cytosol to the nucleus (Xenopus tropicalis)


name: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + H(+)


name: dihydroxyacetone phosphate + hexadecanoyl-CoA = 1-hexadecanoylglycerone 3-phosphate + CoA


name: 3-demethylubiquinol-10 + S-adenosyl-L-methionine = ubiquinol-10 + S-adenosyl-L-homocysteine + H(+)


name: PARVB/Affixin interacts with alpha PIX (Bos taurus)


name: (CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Danio rerio)


name: PRKAA2 regulated nuclear export of NFE2L2 (Bos taurus)


name: a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+) => a 1,2-diacyl-sn-glycerol + ATP


name: BH2 binding can lead to eNOS uncoupling (Dictyostelium discoideum)


name: MECOM (KMT8E), PRDM16 (KMT8F) methylate lysine-10 of replicative histone H3 (H3K9) (Homo sapiens)


name: 2-(methylsulfanyl)acetyl-CoA + butan-1-ol => butyl 2-(methylsulfanyl)acetate + CoA


name: (2E,4Z)-5-hydroxypenta-2,4-diene-1,2,5-tricarboxylate + NADH + 2 H(+) => 2-hydroxy-5-carboxymethylmuconate semialdehyde + NAD(+) + H2O


name: SLC2A2 tetramer transports Fru, Gal, Glc from cytosol to extracellular region (Bos taurus)


name: SLC7A8-mediated uptake of neutral amino acids (Rattus norvegicus)


name: Binding of AP1 transcriptional activator complexes to CCND1 promoter (Homo sapiens)


name: 5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Danio rerio)


name: Association of Nek2A with MCC:APC/C (Danio rerio)


name: 11cROL translocates from Muller cells to cone photoreceptor cells (Xenopus tropicalis)


name: N(6),N(6)-dimethyl-L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-homocysteine + 2 H(+) => L-lysyl(27)-[histone H3] + 2 S-adenosyl-L-methionine


name: beta-D-glucuronate + NAD(+) = D-glucaro-1,5-lactone + NADH + H(+)


name: inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels


name: regulation of SMAD protein nuclear translocation


name: an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate => an alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+)


name: TXNIP binds reduced thioredoxin (Bos taurus)


name: BMT2 (SAMTOR) binds S-adenosylmethionine and dissociates from KICSTOR:GATOR1 (Rattus norvegicus)


name: 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycerol + H2O => 2-octadecanoylglycerol + (9Z)-octadecenoate + H(+)


name: [(1->2)-beta-D-glucosyl](n) + phosphate => [(1->2)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate


name: GTSE1 binds microtubule lattice in interphase cells (Rattus norvegicus)


name: androst-4-ene-3,17-dione + NADPH + H(+) <=> 5beta-androstane-3,17-dione + NADP(+)


name: Cation influx mediated by TRPC3/6/7 (Caenorhabditis elegans)


name: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH4(+)


name: 3-hydroxy-2-methylpyridine-5-carboxylate + CO2 => 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+)


name: a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a monoacyl-sn-glycero-3-phosphocholine + a 1,3-diacyl-sn-glycerol


name: ERCC3-facilitated RNA Pol II backtracking in TC-NER (Canis familiaris)


name: sphinga-4E,14Z-dienine + octadecanoyl-CoA <=> N-octadecanoyl-sphinga-4E,14Z-dienine + CoA + H(+)


name: L-cysteate + phosphate => O-phospho-L-serine + sulfite + H(+)


name: 17beta-estradiol 17-O-(beta-D-glucuronate)(out) => 17beta-estradiol 17-O-(beta-D-glucuronate)(in)


name: a thiol + 3'-phosphoadenylyl sulfate => S-alkyl thiosulfate + adenosine 3',5'-bisphosphate + H(+)


name: GLB1 hydrolyses a glycosaminoglycan (Bos taurus)


name: down regulation of hexokinase type II activity


name: ADD1:ADD3 binds DMTN (Drosophila melanogaster)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Homo sapiens)


name: Sec is reduced to H2Se by PXLP-K259-SCLY dimer (Canis familiaris)


name: LDLR [endosome membrane] => LDLR [plasma membrane] (Homo sapiens)


name: proatranorin III + S-adenosyl-L-methionine = atranorin + S-adenosyl-L-homocysteine


name: PIAS1 SUMOylates DDX5 with SUMO2 (Homo sapiens)


name: glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Xenopus tropicalis)


name: 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: 2 adenosylcob(III)yrinate a,c-diamide + 2 triphosphate + oxidized [electron-transfer flavoprotein] + 3 H(+) => 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] + 2 ATP


name: fibrin multimer, crosslinked:tissue plasminogen activator (one-chain) + plasminogen activator inhibitor 1 -> fibrin multimer, crosslinked:tissue plasminogen activator (one-chain):plasminogen activator inhibitor 1 (Danio rerio)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-sn-glycero-2,3-cyclic phosphate + choline


name: Budding of connexon-containing transport vesicles from the Golgi (Bos taurus)


name: GDP-alpha-D-glucose + alpha-D-mannose 1-phosphate = alpha-D-glucose 1-phosphate + GDP-alpha-D-mannose


name: MYH9- and RNF213-ALK fusions are phosphorylated (Homo sapiens)


name: Lsm1-7 Complex binds deadenylated mRNA (Canis familiaris)


name: cortisol + 3'-phosphoadenylyl sulfate <=> cortisol 21-sulfate + adenosine 3',5'-bisphosphate + H(+)


name: Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA (Canis familiaris)


name: 7-oxocholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 oxidized [adrenodoxin] + H2O


name: (3E,5R)-5-carboxy-2-oxohept-3-enedioate + H(+) <=> (2Z,4Z)-2-hydroxyhepta-2,4-diene-1,7-dioate + CO2


name: HLCS biotinylates 6x(PCCA:PCCB) (Xenopus tropicalis)


name: 3-oxosphinganine + (9Z)-hexadecenoyl-CoA = N-(9Z-hexadecenoyl)-3-oxosphinganine + CoA + H(+)


name: a long-chain alcohol wax ester + CoA => a long chain fatty alcohol + a fatty acyl-CoA


name: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity


name: Association of procollagen type XXI (Drosophila melanogaster)


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Homo sapiens)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Canis familiaris)


name: C dimer localizes to nucleus (Homo sapiens)


name: positive regulation of cytochrome oxidase activity


name: glucose dehydrogenase (acceptor) activity


name: Ubiquitin-dependent degradation of the Smad complex terminates BMP2 signalling (Homo sapiens)


name: Elongation Of The Telomeric Chromosome End (Gallus gallus)


name: ABCB11 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)


name: Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Gallus gallus)


name: ARSA removes sulfate from SM3 (Bos taurus)


name: Proteasomal cleavage of partially digested antigen (immunoproteasome catalyst) (Mus musculus)


name: SLC4A1 exchanges cytosolic HCO3- for extracellular Cl- (Drosophila melanogaster)


name: 2xENPP1 hydrolyzes FAD to FMN (Xenopus tropicalis)


name: Association of RAD52 with the RPA complex at resected DNA DSBs (Danio rerio)


name: D-galacturonate + ATP <=> 1-phospho-alpha-D-galacturonate + ADP + H(+)


name: G6PD multimers dehydrogenate G6P (Homo sapiens)


name: SUMO-p-N protein dimer binds genomic RNA (Homo sapiens)


name: 1-O-octadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => 1-(1Z-octadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: (2Z,6E)-farnesyl diphosphate => (E)-alpha-bisabolene + diphosphate


name: Translocation of BIM to mitochondria (Canis familiaris)


name: (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde + H(+) <=> 2-aminomuconate 6-semialdehyde + CO2


name: (1S,4S)-4-[(4-hydroxyphenyl)methyl]-2,5-diazaspiro[bicyclo[3.2.1]octane-6,1'-cyclohexan]-4'-one + S-adenosyl-L-methionine <=> (1S,4S)-4-[(4-methoxyphenyl)methyl]-2,5-diazaspiro[bicyclo[3.2.1]octane-6,1'-cyclohexan]-4'-one + S-adenosyl-L-homocysteine + H(+)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O <=> 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + octadecanoate + H(+)


name: Formation of the PA28-alpha-beta-20S proteasome (Danio rerio)


name: BOD1L1 binds SET1A complex (Mus musculus)


name: PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Saccharomyces cerevisiae)


name: BIL:ALB scavenges O2.- (Xenopus tropicalis)


name: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA (THCA-CoA) is hydrated to (24R, 25R) 3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA (Mus musculus)


name: EHMT1:EHMT2 complex binds E2F6.com-1 core (Drosophila melanogaster)


name: GDIs block activation of RHOA (Gallus gallus)


name: tardioxopiperazine A + dimethylallyl diphosphate <=> echinulin + diphosphate


name: acid sphingomyelin phosphodiesterase activity


name: beta-D-galactosyl-(1<->1')-N-octadecanoylsphing-4-enine + H2O = N-octadecanoylsphing-4-enine + D-galactose


name: 1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-2-acetyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate => 2 5-dehydro-4-deoxy-D-glucuronate


name: 4,4-dimethyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-8-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O


name: (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H2O + H(+) => (2S,6S)-2,6-diaminopimelate + 2-oxoglutarate


name: 9-cis-4-hydroxyretinoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-cis-4-oxoretinoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: PAK1 phosphorylates myosin phosphatase (Gallus gallus)


name: Recognition and binding of the HIV-1 mRNA cap by the cap-binding complex (Homo sapiens)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Saccharomyces cerevisiae)


name: Formation of the CF I complex (Canis familiaris)


name: SLCO4C1 mediates the transport of digoxin (Caenorhabditis elegans)


name: EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:phospho-GAB1 binds PI3K (Sus scrofa)


name: MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Homo sapiens)


name: 2 3-amino-1,5-dihydropyridine-2,6-dione + O2 => indigoidine + 2 H2O


name: MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Xenopus tropicalis)


name: ATP-dependent release of CDT1 from the OCCM complex (Homo sapiens)


name: Decreased Sympathetic Histamine Activity


name: Keratin filament formation (Xenopus tropicalis)


name: ubiquinol-8 + S-adenosyl-L-homocysteine + H(+) => 3-demethylubiquinol-8 + S-adenosyl-L-methionine


name: PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Canis familiaris)


name: PRMT1 arginine-methylates RUNX1 (Mus musculus)


name: Increased Cerebral Cortex Enkephalin Activity


name: (E)-cinnamate + NADPH + O2 + H(+) <=> trans-2-coumarate + NADP(+) + H2O


name: MTMR12 binds MTMR2 (Caenorhabditis elegans)


name: PI3P is dephosphorylated to PI by MTM proteins at the early endosome membrane (Drosophila melanogaster)


name: Glycine, Serine and Threonine Metabolism Pathway


name: IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 (Gallus gallus)


name: all-trans-4-hydroxy-13,14-dihydroretinoate + reduced [NADPH--hemoprotein reductase] + O2 <=> all-trans-4-oxo-13,14-dihydroretinoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: thromboxane B2 + NAD(+) = 11-dehydro-thromboxane B2 + NADH + H(+)


name: coproporphyrinogen III(out) + ADP + phosphate + H(+) => coproporphyrinogen III(in) + ATP + H2O


name: ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Homo sapiens)


name: Dual-specific AKAPs bind type I and II PKA regulatory subunits (Schizosaccharomyces pombe)


name: MET bound PI3K generates PIP3 (Homo sapiens)


name: p-T,Y MAPKs dimerize (Rattus norvegicus)


name: 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Mus musculus)


name: GAA hydrolyzes lysosomal glycogen (Rattus norvegicus)


name: SLC35D2 mediates the antiport of GDP-mannose in exchange for GMP (Rattus norvegicus)


name: (S)-3-(indol-3-ylmethyl)-6,7,8,8a-tetrahydropyrrolo[1,2-a]pyrazin-1-one + A + H(+) <=> 1-hydroxy-3-(indol-3-ylmethyl)-6H,7H,8H-5lambda(5)-pyrrolo[1,2-a]pyrazine + AH2


name: (2E,6E,10E)-geranylgeranyl diphosphate => phomopsene + diphosphate


name: CBL ubiquitinates FRS2 and FGFR1 (Drosophila melanogaster)


name: cellulose synthase (UDP-forming) activity


name: STAT4 binds to IL12RB2 in Interleukin-12 receptor complex (Sus scrofa)


name: ADRB2:GRK complex dissociates to Phosphorylated ADRB2 (Bos taurus)


name: RUNX3 binds TEADs and YAP1 (Caenorhabditis elegans)


name: Addition of nucleotides between position +11 and +30 (Homo sapiens)


name: NUDT19 hydrolyses acyl-CoA to 3',5'-ADP and acyl-PPANT (Canis familiaris)


name: (E)-sinapoyl actetate + CoA => (E)-sinapyl alcohol + acetyl-CoA


name: Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Caenorhabditis elegans)


name: RAB3IP stimulates nucleotide exchange on RAB8A (Sus scrofa)


name: down regulation of coenzyme Q8 biosynthesis


name: p-Y753,Y759-PLCG2 translocates from cytosol to plasma membrane (Dictyostelium discoideum)


name: ALOX12:Fe2+ oxidises DPAn-3 to 14(S)-Hp-DPAn-3 (Sus scrofa)


name: BAP1 disrupts the BRCA1:BARD1 heterodimer (Dictyostelium discoideum)


name: Activated protein C:PROCR binds F2R (Mus musculus)


name: a ganglioside Ac-O-7-GD1b => a ganglioside Ac-O-8-GD1b


name: XP-C binds to RAD23B forming a heterodimer (Gallus gallus)


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Dictyostelium discoideum)


name: cis-SNARE binds SNAPs and NSF hexamer at the TGN (Saccharomyces cerevisiae)


name: L-ribulose 5-phosphate = L-xylulose 5-phosphate


name: GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Mus musculus)


name: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + NADH + H(+)


name: 2 a ubiquinol + O2 = 2 a ubiquinone + 2 H2O


name: p-Y705-STAT3 dissociates from IL6 receptor (Mus musculus)


name: (2Z,6E)-farnesyl diphosphate => gamma-cadinene + diphosphate


name: 5beta-pregnan-3alpha,11beta,17alpha,20beta,21-pentol + NAD(+) = tetrahydrocortisol + NADH + H(+)


name: questin hydroquinone + NADP(+) => questin + NADPH + 2 H(+)


name: 3-dehydroshikimate <=> 3,4-dihydroxybenzoate + H2O


name: TRMT11:TRMT112 methylates guanosine-10 in tRNA (Homo sapiens)


name: [DsrC protein]-S-sulfanyl-L-cysteine/L-cysteine + 2 A + 3 H2O => [DsrC protein]-dithiol + sulfite + 2 AH2 + 2 H(+)


name: propan-2-ol:coenzyme F420 oxidoreductase activity


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Xenopus tropicalis)


name: factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) (Rattus norvegicus)


name: abacavir + 2 NAD+ => abacavir 5'-carboxylate + 2 NADH + 2 H+ (Gallus gallus)


name: Adenylate cyclase converts ATP into cyclic AMP (Gallus gallus)


name: ACOT2,9,THEM4,5 hydrolyse MCFA-CoA, LCFA-CoA (Mus musculus)


name: pseudouridine(65) in tRNA => uridine(65) in tRNA


name: CYP2E1 monooxygenates APAP to NAPQI (Mus musculus)


name: testosterone + reduced [NADPH--hemoprotein reductase] + O2 => 15alpha,17beta-dihydroxyandrost-4-en-3-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a ganglioside GD2 (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD2(d18:1(4E)) + CoA


name: abscisic acid transmembrane transporter activity


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Canis familiaris)


name: Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)


name: Branching and elongation of mother and daughter filaments (Saccharomyces cerevisiae)


name: (Z)-alkanethial oxide => (E)-alk-1-en-1-SO-peroxol


name: a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H(+) => a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine


name: RHOD translocates to the Golgi membrane (Homo sapiens)


name: a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + ethanolamine => a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + choline


name: nitroxyl + 2 Fe(II)-[cytochrome c] + O2 + H(+) <=> 2 Fe(III)-[cytochrome c] + nitrite + H2O


name: STARD7 transports Q10 to plasma membrane (Canis familiaris)


name: dimethylsulfonioacetate + L-homocysteine = (methylsulfanyl)acetate + L-methionine + H(+)


name: pelargonidin 3-O-(6-O-[(E)-caffeoyl]-beta-D-glucoside) 5-O-beta-D-glucoside + malonyl-CoA <=> 4'''-demalonylsalvianin + CoA


name: (22R)-hydroxycholesterol + 2 reduced [adrenodoxin] + O2 + 2 H(+) = (20R,22R)-20,22-dihydroxycholesterol + 2 oxidized [adrenodoxin] + H2O


name: Active LTK binds GRB2:TNK2 (Homo sapiens)


name: Monoubiquitinated N-myristoyl GAG polyprotein is targeted to the late endosomal vesicle membrane by the ESCRT-I complex (Homo sapiens)


name: XPO1 (CRM1) binds to BACH1:Hemes (Rattus norvegicus)


name: heptan-2-one + hydrogen cyanide => (2S)-2-hydroxy-2-methylheptanenitrile


name: Activated FGFR3:p-FRS bind to PPTN11 (Canis familiaris)


name: dGTP + H2O => 2'-deoxyguanosine + triphosphate + H(+)


name: 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate)(in) + ATP + H2O => 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)


name: rifampicin ortho-naphthoquinone carboxamide <=> rifampicin para-naphthoquinone carboxamide


name: (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-methionine = N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline + S-adenosyl-L-homocysteine + H(+)


name: Sodium Taurocholate Co-transporting Polypeptide Inhibitors


name: LCAT + discoidal HDL <=> LCAT:discoidal HDL complex (Sus scrofa)


name: Xaa-L-Pro dipeptide + H2O => an L-alpha-amino acid + L-proline


name: dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Homo sapiens)


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA => 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA


name: SENP1,2,5 proteolytically process SUMO1 (Sus scrofa)


name: PYCR1 decamer reduces (S)-1-pyrroline-5-carboxylate to L-Pro (Mus musculus)


name: MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Xenopus tropicalis)


name: misspliced mutants of LRP5 support enhanced beta-catenin-dependent signaling (Homo sapiens)


name: 1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-(9Z-octadecenoyl)-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: pheophorbide a(out) + ADP + phosphate + H(+) => pheophorbide a(in) + ATP + H2O


name: positive regulation of catalytic activity


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + CDP-choline => 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CMP + H(+)


name: CYP3A7 can 6beta-hydroxylate testosterone (Homo sapiens)


name: TRAF3:NIK binds TRAF2:cIAP1/2 (Canis familiaris)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: nitrite(in) + H(+)(out) = nitrite(out) + H(+)(in)


name: BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 (Sus scrofa)


name: (2E,4E,6E)-octa-2,4,6-trienyl-[ACP] + 4 malonyl-CoA + AH2 + 3 H(+) <=> 2,4-dihydroxy-6-[(3E,5E,7E)-2-oxonona-3,5,7-trienyl]benzaldehyde + holo-[ACP] + A + 4 CO2 + 4 CoA + H2O


name: N-formimidoyl-L-glutamate + H2O <=> N-formyl-L-glutamate + NH4(+)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA => 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + CoA


name: K(+)(out) + L-cysteine(in) + 3 Na(+)(in) + H(+)(in) => K(+)(in) + L-cysteine(out) + 3 Na(+)(out) + H(+)(out)


name: a 1,2-diacyl-sn-glycero-3-phosphate + H2O <=> a 1,2-diacyl-sn-glycerol + phosphate


name: pentyl sulfate + 2-oxoglutarate + O2 => pentanal + sulfate + succinate + CO2 + H(+)


name: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate => UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate


name: a 2-acylglycerol + H2O <=> glycerol + a fatty acid + H(+)


name: WLS dissociates from retromer (Caenorhabditis elegans)


name: PKC phosphorylates sphingosine kinase 1 (Schizosaccharomyces pombe)


name: SARS-CoV-1 dsRNA intermediates bind DDX58 (Homo sapiens)


name: a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(out) = a beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine(in)


name: an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + H2O => an alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + acetate


name: 9alpha-copalyl diphosphate = stemar-13-ene + diphosphate


name: PE is converted to PS by PTDSS2 (Sus scrofa)


name: ABC-type fatty-acyl-CoA transporter activity


name: aldosterone hemiacetal + UDP-alpha-D-glucuronate <=> aldosterone hemiacetal 18-beta-glucuronide + UDP + H(+)


name: CHEK2 phosphorylates BRCA1 (Canis familiaris)


name: MMP2, MMP9 cleave SCUBE3 (Canis familiaris)


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Canis familiaris)


name: 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP => 4-CDP-2-C-methyl-D-erythritol 2-phosphate


name: histo-blood substance beta-dependent galactosyltransferase activity


name: 9beta-pimara-7,15-diene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 9beta-pimara-7,15-dien-19-oate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)


name: a 2-(omega-methylsulfanyl)alkylmalate => a 3-(omega-methylsulfanyl)alkylmalate


name: KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Bos taurus)


name: N-hydroxy-2-acetylaminofluorene + PAPS => 2-acetylaminofluorene-N-sulfate + PAP (Sus scrofa)


name: GUSB tetramer hydrolyzes GlcA-β1,3-GlcNAc (Danio rerio)


name: The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Drosophila melanogaster)


name: pyridoxine + ATP = pyridoxine 5'-phosphate + ADP + H(+)


name: N-acetyl-alpha-D-muramate 1-phosphate + UDP + H(+) <=> UDP-N-acetyl-alpha-D-muramate + phosphate


name: (3R)-3-hydroxy-10'-apo-beta-carotenal + O2 => 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial + (3R)-hydroxy-beta-ionone


name: 12-hydroxyoctadecanoyl-CoA + 3 malonyl-CoA + 3 H(+) <=> 4-hydroxy-6-(13-hydroxy-2-oxononadecyl)pyran-2-one + 3 CO2 + 4 CoA


name: 4beta-methylzymosterol-4alpha-carbaldehyde + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 4beta-methylzymosterol-4alpha-carboxylate + 2 Fe(III)-[cytochrome b5] + H2O


name: GAPDH tetramers reduce 1,3BPG to GA3P (Drosophila melanogaster)


name: 1/3-PP-IP5 transports from the cytosol to the nucleus (Mus musculus)


name: 14-3-3 proteins bind AKT-phosphorylated FOXO3 (Danio rerio)


name: Formation of RAD52 heptameric ring structure complexes (Danio rerio)


name: apo-UQCRFS1 binds LYRM7 (Xenopus tropicalis)


name: (2E)-dodecenoyl-CoA + H2O => (3S)-3-hydroxydodecanoyl-CoA


name: GST dimers cleave AZA to 6MP (Gallus gallus)


name: Mcm4,6,7 trimer forms and associates with the replication fork (Mus musculus)


name: L-glutamate 5-semialdehyde + acetyl-CoA <=> N-acetyl-L-glutamate 5-semialdehyde + CoA + H(+)


name: UDP-alpha-D-galactose(in) + AMP(out) => UDP-alpha-D-galactose(out) + AMP(in)


name: PHF6 binds SWI/SNF complexes (Sus scrofa)


name: Decreased Peripheral Nervous System GABA Activity


name: USP8 deubiquitinates STAM2:HGS (Xenopus tropicalis)


name: p-S585-IL3RB binds 14-3-3 proteins (Bos taurus)


name: SUMOylation of XPC with SUMO1 (Homo sapiens)


name: (Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 => (-)-4'-methoxycyclopenine + succinate + CO2


name: lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Rattus norvegicus)


name: 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine


name: sulfosungeidine E => sungeidine B + sulfate + H(+)


name: 5-dehydroepisterol + NADP(+) + 2 H2O => ergosta-5,7-dien-3betabeta-ol + NADPH + O2 + H(+)


name: ethyl benzoate + CoA => ethanol + benzoyl-CoA


name: EXA4 is converted to EXC4 by LTC4S (Sus scrofa)


name: PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Homo sapiens)


name: neurotransmitter receptor regulator activity


name: [(1->4)-alpha-D-galacturonosyl](n) + H2O = alpha-D-galacturonate + [(1->4)-alpha-D-galacturonosyl](n-1)


name: DNA 5-methylcytosine dioxygenase activity


name: GSK3B phosphorylates CD274 (Gallus gallus)


name: PMEPA1 sequesters phosphorylated SMAD2/3 (Homo sapiens)


name: Fringe-modified Pre-NOTCH is cleaved by FURIN (Homo sapiens)


name: soyasapogenol E + UDP-alpha-D-glucuronate <=> soyasapogenol E 3-O-beta-D-glucuronate + UDP + H(+)


name: GTP-bound RAC1 and CDC42 bind IQGAPs (Rattus norvegicus)


name: (1R,6R)-6-hydroxy-2-succinyl-cyclohexa-2,4-diene-1-carboxylate <=> 2-succinylbenzoate + H2O


name: 6-hydroxy-N-methylmyosmine + H2O2 => (S)-6-hydroxynicotine + O2


name: fumitremorgin B + 2-oxoglutarate + AH2 + 2 O2 <=> verruculogen + succinate + A + CO2 + H2O


name: ATP Hydrolysis By Myosin (Rattus norvegicus)


name: hexadecyl (9Z)-hexadecenoate + CoA => hexadecan-1-ol + (9Z)-hexadecenoyl-CoA


name: Cleavage of dihydrouracil by NTHL1 glycosylase (Gallus gallus)


name: SLCO1A2 transports Cipro(1+) into the cytosol (Sus scrofa)


name: USP7 deubiquitinates MDM2 (Homo sapiens)


name: Myeloperoxidase (MPO) catalyzes oxidation of nitrite to nitrogen dioxide (Rattus norvegicus)


name: 7alpha-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 => (24S)-7alpha-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA <=> 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: glycine betaine(out) + Na(+)(out) = glycine betaine(in) + Na(+)(in)


name: Mo-molybdopterin + AMP + 2 H(+) => adenylyl MoO2(OH)-molybdopterin cofactor + H2O


name: ALOX12:Fe2+ oxidises DHA to 14(S)-Hp-DHA (Homo sapiens)


name: EXO1 excises single strand DNA surrounding a U:G mismatch (Bos taurus)


name: TXLNA (IL14) binds syntaxin3 (Danio rerio)


name: 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + 2 H(+) => 3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O


name: PDE3B hydrolyses cAMP to AMP (Mus musculus)


name: PDE5A dimer binds PDE5A inhibitors (Rattus norvegicus)


name: Myristoylation of tBID by NMT1 (Danio rerio)


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 15,20-dihydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: tauronorcholate(in) + 2 Na(+)(in) => tauronorcholate(out) + 2 Na(+)(out)


name: a 2-oxocarboxylate + a quinol + NH4(+) => a D-alpha-amino acid + a quinone + H2O


name: DOCK7 activates RAC1 (Rattus norvegicus)


name: SLC44A1 and SLC44A2 transport Cho from cytosol to mitochondrial matrix (Mus musculus)


name: NEU4 hydrolyses Neu5Ac from glycoconjugates (Sus scrofa)


name: PGM2L1:Mg2+ phosphorylates G6P to G1,6BP (Drosophila melanogaster)


name: dihydro-ML-236C carboxylate + reduced [NADPH--hemoprotein reductase] + O2 <=> ML-236C carboxylate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Danio rerio)


name: RHOF GAPs stimulate RHOF GTPase activity (Gallus gallus)


name: NRPE condenses with atRAL to form A2PE (Homo sapiens)


name: heme b + 5 AH2 + 4 O2 + 2 H(+) => beta-staphylobilin + Fe(2+) + formaldehyde + 5 A + 4 H2O


name: CYSLTR1 binds LTC4,LTD4,LTE4 (Rattus norvegicus)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Xenopus tropicalis)


name: FNTA:PGGT1B geranylgeranylates GBP5 (Dictyostelium discoideum)


name: ATR Kinase is recruited to unsynapsed regions (Homo sapiens)


name: vincristine(out) + ADP + phosphate + H(+) => vincristine(in) + ATP + H2O


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Homo sapiens)


name: trimethylamine N-oxide + menaquinol-8 + H(+) => trimethylamine + menaquinone-8 + H2O


name: RHOBTB1 binds GTP (Dictyostelium discoideum)


name: Elongation of pre-rRNA transcript (Gallus gallus)


name: NaS1 co-transports sulphate and a sodium ion (Xenopus tropicalis)


name: (25R)-3beta-hydroxycholest-5-en-7-one-26-al + 2 oxidized [adrenodoxin] + 2 H2O => (25R)-3beta,26-dihydroxycholest-5-en-7-one + 2 reduced [adrenodoxin] + O2 + 2 H(+)


name: Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)


name: Neuropeptide S receptor binds neuropeptide S (Sus scrofa)


name: 4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NADP(+) = 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADPH + H(+)


name: cis-1,2-dithiane-4,5-diol + hydrogen sulfide + sulfite + 2 H(+) => dithioerythritol + thiosulfate


name: Association of procollagen type XVII (Bos taurus)


name: Activated FGFR1 binds FRS2 (Mus musculus)


name: 4-O-[(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CDP-glycerol <=> 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + CMP + H(+)


name: Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2 (Mus musculus)


name: Cholest-5-ene-3beta,7alpha,27-triol is oxidized and isomerized to 4-cholesten-7alpha,27-diol-3-one (Drosophila melanogaster)


name: class D G protein coupled receptor activity


name: [(1->4)-N-acetyl-beta-D-glucosaminyl](n-2) + N,N'-diacetylchitobiose => [(1->4)-N-acetyl-beta-D-glucosaminyl](n) + H2O


name: ATF6 (ATF6-alpha) translocates from the endoplasmic reticulum to the Golgi (Bos taurus)


name: RNF20:RNF40 monoubiquitinates Histone H2B (Rattus norvegicus)


name: PCSK9 binds PCSK9 inhibitors (Sus scrofa)


name: L-histidyl-[ribosomal protein uL15] + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-histidyl-[ribosomal protein uL15] + succinate + CO2


name: Activated NFκB complex binds IL6 gene promoter (Homo sapiens)


name: SMAC (DIABLO) binds XIAP (Gallus gallus)


name: PEX19:class I PMP binds PEX3 (Gallus gallus)


name: PCSK5 mediates dissociation of 2 x LPL from GPIHBP1:HSPG:LPL dimer (Bos taurus)


name: Regulation of KIF20A (MKL2) by phosphorylation (Drosophila melanogaster)


name: diosgenin + UDP-alpha-D-glucose = diosgenin 3-O-beta-D-glucoside + UDP + H(+)


name: N-methyl-D-dopa + O2 = (3R)-7,8-dihydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate + H2O2


name: UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) activity


name: 4-nitrobenzoyl-CoA + 6 (S)-methylmalonyl-CoA + malonyl-CoA + 6 NADPH + 12 H(+) = demethyldeoxyspectinabilin + 7 CO2 + 6 NADP(+) + 8 CoA + 5 H2O


name: spectinabilin polyketide synthase system


name: hydroxymethylphosphonate + O2 <=> formate + phosphate + 2 H(+)


name: PS moves from ER to lysosome (Homo sapiens)


name: ATP4A:ATP4B binds PPIs (Canis familiaris)


name: SLC43A1 (LAT3)-mediated uptake of large neutral amino acids (Sus scrofa)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Drosophila melanogaster)


name: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + H2O + H(+) = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + NH4(+)


name: PPT2 hydrolyses PALMCoA to PALM (Dictyostelium discoideum)


name: PEX7 binds cargo proteins containing PTS2 (Mus musculus)


name: 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + H(+) => 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + L-cysteine + ATP


name: Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 (Mus musculus)


name: p-S225-SPHK1 localizes to cytosol (Dictyostelium discoideum)


name: CBL binds and ubiquitinates phosphorylated Sprouty (Canis familiaris)


name: TFPIα + FV intermediate + PROS1 => TFPIα:FV intermediate:PROS1 (Gallus gallus)


name: all-trans-beta-carotene + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => beta-cryptoxanthin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: intermembrane glycolipid transfer activity


name: L-cysteinyl-tRNA(Cys) + AMP + diphosphate => tRNA(Cys) + L-cysteine + ATP


name: gamma-lactone-2-keto[5.5.5.5]fenestrane + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+) => silphinene-15-oate + 2 reduced [NADPH--hemoprotein reductase] + 2 O2


name: lovastatin carboxylate + holo-[2-methylbutanoate polyketide synthase] => monacolin J carboxylate + (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase]


name: SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Caenorhabditis elegans)


name: Stalled 55S mitochondrial ribosome is dissociated to yield 28S subunit and 39S subunit:mRNA:peptidyl-tRNA:tRNA (Bos taurus)


name: beta-D-gentiobiosyl crocetin + UDP-alpha-D-glucose <=> beta-D-gentiobiosyl beta-D-glucosyl crocetin + UDP


name: glutamine family amino acid catabolic process


name: positive regulation of maltoheptaose metabolic process


name: an N-acylethanolamine + sn-glycerol 3-phosphate + H(+) => N-acyl-sn-glycero-3-phosphoethanolamine + H2O


name: Formation of the BBSome (Caenorhabditis elegans)


name: activation of tyrosine phosphorylation of Stat2 protein


name: LONP1 binds mitochondrial inner membrane proteins (Danio rerio)


name: (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + O2 = (2E,4Z,7Z,10Z,13Z,16Z)-docosahexaenoyl-CoA + H2O2


name: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + NADH + H(+)


name: coproporphyrin I(out) + ADP + phosphate + H(+) => coproporphyrin I(in) + ATP + H2O


name: D-mannose(out) + n Na(+)(out) = D-mannose(in) + n Na(+)(in)


name: (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate => (9Z,12Z)-octadecadienoate + O2


name: lipid A-core heptosyltransferase activity


name: 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Bos taurus)


name: an N(6)-methyladenosine in mRNA + S-adenosyl-L-homocysteine + H(+) => an adenosine in mRNA + S-adenosyl-L-methionine


name: Polyubiquitinated RUNX3 translocates to the cytosol (Bos taurus)


name: holo-[BtrI ACP] + adenosine 3',5'-bisphosphate + H(+) => apo-[BtrI ACP] + CoA


name: D-maltose(out) + N(pros)-phospho-L-histidyl-[protein] <=> alpha-maltose 6'-phosphate(in) + L-histidyl-[protein]


name: PDGF binds to extracellular matrix proteins (Mus musculus)


name: D-erythrose 4-phosphate + D-xylulose 5-phosphate = beta-D-fructose 6-phosphate + D-glyceraldehyde 3-phosphate


name: butanoate(out) + Na(+)(out) <=> butanoate(in) + Na(+)(in)


name: DeHA hydrolyses to threonate and oxalate (Homo sapiens)


name: lactose + an N-acyl-sphingoid base => a beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide + H2O


name: 2'-O-methylguanosine(1145) in 16S rRNA + S-adenosyl-L-homocysteine + H(+) => guanosine(1145) in 16S rRNA + S-adenosyl-L-methionine


name: (2E,6E)-farnesyl diphosphate + H2O <=> patchoulol + diphosphate


name: Increased Cerebral Cortex Serotonin Activity


name: lipid A + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + H(+) <=> lipid A 4'-(2-aminoethyl diphosphate) + a 1,2-diacyl-sn-glycerol


name: choline biosynthetic process via N-monomethylethanolamine


name: 11-deoxycortisol + 2 reduced [adrenodoxin] + O2 + 2 H(+) => cortisol + 2 oxidized [adrenodoxin] + H2O


name: calcitriol + UDP-alpha-D-glucuronate <=> calcitriol 25-O-(beta-D-glucuronide) + UDP + H(+)


name: I(1,3,4,5)P4 is dephosphorylated to I(1,3,4)P3 by INPP5[3]/ITPK1 in the cytosol (Canis familiaris)


name: TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4  (Canis familiaris)


name: 1,6-dihydroxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-methionine = 1-hydroxy-6-methoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-homocysteine


name: hydrocaffeoyl-CoA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 NAD(+) <=> (E)-caffeoyl-CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 NADH


name: sulfate assimilation via adenylyl sulfate reduction


name: ASRGL1 hydrolyses aspartame to L-Asp, L-Phe, MeOH (Danio rerio)


name: PLK3 phosphorylates CDC25A (Mus musculus)


name: histamine + S-adenosyl-L-methionine <=> N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+)


name: EP300 acetylates histone H2A, H2B, H3, H4 (Drosophila melanogaster)


name: RTC binds SARS-CoV-1 genomic RNA complement (minus strand) (Homo sapiens)


name: KDM8:Fe2+ hydroxylates an arginine residue of RCCD1 (Xenopus tropicalis)


name: 2,4-dimethylbenzyl alcohol + O2 <=> 2,4-dimethylbenzaldehyde + H2O2


name: 1,2-dihexanoyl-sn-glycerol + (9Z)-octadecenoyl-CoA => 1,2-dihexanoyl-3-(9Z-octadecenoyl)-sn-glycerol + CoA


name: LONP1 binds mitochondrial matrix proteins (Schizosaccharomyces pombe)


name: Acetylation of SMC3 subunit of centromeric chromatin associated cohesin by ESCO1 or ESCO2 (Gallus gallus)


name: GLUT3 (SLC2A3) tetramer transports Glc from extracellular region to cytosol (Caenorhabditis elegans)


name: (glutathione)4[2Fe(III)-2S] cluster(in) + ATP + H2O => (glutathione)4[2Fe(III)-2S] cluster(out) + ADP + phosphate + H(+)


name: HSD17B4 hydrates trans-2,3-dehydrohexacosanoyl-CoA (Dictyostelium discoideum)


name: UDP-2-acetamido-2-deoxy-alpha-D-glucuronate + H(+) = UDP-N-acetyl-alpha-D-xylosamine + CO2


name: COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Danio rerio)


name: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + NADPH + H(+)


name: E-selectin binds E-selectin ligand (Mus musculus)


name: A1 and A3 receptors bind adenosine (Drosophila melanogaster)


name: 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CoA <=> (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + acetyl-CoA


name: L-thyroxine(out) + L-glutamate(in) => L-thyroxine(in) + L-glutamate(out)


name: PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane (Homo sapiens)


name: p-STAT3 dissociates from IL24:IL22RA1:p‑JAK1:IL20RB:p‑STAT3 (Homo sapiens)


name: plasminogen activation in another organism


name: STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Rattus norvegicus)


name: 3-methylmalate + CoA + H(+) => propanoyl-CoA + glyoxylate + H2O


name: dinoflagellate luciferin + O2 = oxidized dinoflagellate luciferin + hnu + H2O + H(+)


name: 2,5-dihydroxybenzoate + H(+) => hydroquinone + CO2


name: Chromokinesins form dimers (Gallus gallus)


name: 6-kestotriose + sucrose = 6,6-kestotetraose + beta-D-glucose


name: (R)-octopamine = (4-hydroxyphenyl)acetaldehyde + NH4(+)


name: 4alpha-methyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) => 4alpha-carboxy-5alpha-cholest-7-en-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O


name: PTGS2 dimer oxidises DHA to 13-HDHA (Danio rerio)


name: MAP2K2 phosphorylates MAPK1 (Rattus norvegicus)


name: RFC dissociates after sliding clamp formation on the C-strand of the telomere (Bos taurus)


name: CREB3L3 translocates from the endoplasmic reticulum membrane to the Golgi membrane (Homo sapiens)


name: ZnT5 transports zinc into secretory granules in pancreatic beta cells (Schizosaccharomyces pombe)


name: (3R)-hydroxybutanoate trimer + H2O => (3R)-hydroxybutanoate dimer + (R)-3-hydroxybutanoate + H(+)


name: ST3GAL3 transfers Neu5Ac to Type 1 chain to form Type 1 MSGG (Mus musculus)


name: down regulation of janus kinase 3 activity


name: ADPGK:Mg2+ phosphorylates Glc to G6P (Xenopus tropicalis)


name: methylenetetrahydrofolate reductase (ferredoxin) activity


name: thiamine triphosphate + AMP => thiamine diphosphate + ADP


name: (E)-4-coumarate + UDP-alpha-D-glucose => 1-O-[(E)-4-coumaroyl]-beta-D-glucose + UDP


name: AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine (Homo sapiens)


name: NAT8L transfers acetyl group from Ac-CoA to L-Asp, forming NAASP (Mus musculus)


name: Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Drosophila melanogaster)


name: p-2S-SMAD2,3:SMAD4:RBL1:E2F4,5:DP1,2 binds MYC gene promoter (Homo sapiens)


name: Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer (Mus musculus)


name: SMURF2 monoubiquitinates SMAD3 (Xenopus tropicalis)


name: (3S)-3-[2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-4-methylidenecyclohexan-1-one + reduced [NADPH--hemoprotein reductase] + O2 <=> 5-dehydro-6-demethoxyfumagillol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: SLC7A8-mediated uptake of neutral amino acids (Mus musculus)


name: 3-iodo-L-tyrosine + iodide + NADP(+) <=> 3,5-diiodo-L-tyrosine + NADPH + H(+)


name: 4-isopropylphenol + 3'-phosphoadenylyl sulfate <=> 4-isopropylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)


name: (S)-2-hydroxymethylglutarate => 2-methyleneglutarate + H2O


name: non-kinase phorbol ester receptor activity


name: SLCO2B1 has a narrow substrate specificity (Homo sapiens)


name: Digestion of triacylglycerols by extracellular CEL (bile salt-dependent lipase) (Mus musculus)


name: PLK1 phosphorylates NUDC (Drosophila melanogaster)


name: NEK11 phosphorylates CDC25A (Mus musculus)


name: ent-sandaracopimara-8(14),15-diene + reduced [NADPH--hemoprotein reductase] + O2 => ent-sandaracopimaradien-3beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: G alpha (q) in G (q):RGS complex is inactivated (Bos taurus)


name: 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + H2O => sn-glycero-3-phospho-L-serine + hexadecanoate + H(+)


name: sulfate(out) + succinate(in) <=> sulfate(in) + succinate(out)


name: prothrombin -> activated thrombin (factor IIa) + thrombin activation peptide (Xa catalyst) (Homo sapiens)


name: PTPN1 and PTPN2 dephosphorylate MET (Rattus norvegicus)


name: ABCG2 transports Cipro from hepatic cell to extracellular space (Dictyostelium discoideum)


name: 2-(thiiran-2-yl)acetonitrile + sulfate => (Z)-N-(sulfonatooxy)prop-2-enimidothioate


name: (E)-ferulate + UDP-alpha-D-glucose => 1-O-[(E)-feruloyl]-beta-D-glucose + UDP


name: a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O => a 2-acyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+)


name: methylarsonous acid + S-adenosyl-L-methionine <=> dimethylarsinate + S-adenosyl-L-homocysteine + 2 H(+)


name: CYP19A1 hydroxylates TEST to EST17b (Sus scrofa)


name: erythromycin C + S-adenosyl-L-methionine <=> erythromycin A + S-adenosyl-L-homocysteine + H(+)


name: (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2


name: Expression of superoxide dismutase 2 (Homo sapiens)


name: a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine <=> an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine + a 1,3-diacylglycerol


name: Condensin II complex binds H4K20me1-containing nucleosomes (Bos taurus)


name: N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + 3'-phosphoadenylyl sulfate <=> an N(4)-{6-O-sulfo-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L--asparaginyl-[protein] + adenosine 3',5'-bisphosphate + H(+)


name: beta-D-glucose 6-phosphate => alpha-D-glucose 6-phosphate


name: BCO2:Fe2+ cleaves betaC to APO10al and bION (Drosophila melanogaster)


name: urate(in) + ATP + H2O <=> urate(out) + ADP + phosphate + H(+)


name: resolvin E1 + NAD(+) <=> 18-oxo-resolvin E1 + NADH + H(+)


name: Fusion and Release of SARS-CoV-1 Nucleocapsid (Homo sapiens)


name: methylthiol:coenzyme M methyltransferase activity


name: 55S ribosome:MTRF1 hydrolyzes peptidyl-tRNA bond and GTP is hydrolyzed (Rattus norvegicus)


name: positive regulation of response to propan-1-ol


name: citrate(out) + 2 Na(+)(out) = citrate(in) + 2 Na(+)(in)


name: D-glyceraldehyde + NADP(+) + H2O => (R)-glycerate + NADPH + 2 H(+)


name: Recognition and Binding of Core Promoter Elements by TFIID (Drosophila melanogaster)


name: D-threo-isocitrate + NADP(+) <=> 2-oxoglutarate + CO2 + NADPH


name: L-dopa + O2 + H2O + H(+) <=> 3,4-dihydroxyphenylacetaldehyde + H2O2 + NH4(+) + CO2


name: hydroxyacetone + NADP(+) = methylglyoxal + NADPH + H(+)


name: N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + AMP + diphosphate + H(+) => L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphate + ATP


name: ATP2B4 binds to NOS1, inhibiting it (Rattus norvegicus)


name: ANOs transport cytosolic Cl- to extracellular region (Rattus norvegicus)


name: dodecanoyl-CoA + sn-glycerol 3-phosphate => 1-dodecanoyl-sn-glycerol 3-phosphate + CoA


name: an N-carbamoyl-L-alpha-amino acid + H2O + 2 H(+) <=> an L-alpha-amino acid + NH4(+) + CO2


name: NRP-1 forms a ternary complex with VEGF165 and VEGFR1 (Homo sapiens)


name: SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Homo sapiens)


name: a globoside MSGG + CMP-N-acetyl-beta-neuraminate => a globoside DSGG + CMP + H(+)


name: MAF1 translocates to the nucleus (Mus musculus)


name: 1,2-di-(9Z-hexadecenoyl)-sn-glycerol + CDP-ethanolamine <=> 1,2-di-(9Z-hexadecenoyl)-sn-glycero-3-phosphoethanolamine + CMP + H(+)


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Bos taurus)


name: PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Homo sapiens)


name: 1-O-hexadecyl-2-acetyl-sn-glycerol + tetradecanoyl-CoA = 1-O-hexadecyl-2-acetyl-3-tetradecanoyl-sn-glycerol + CoA


name: RAC3 GDIs block activation of RAC3 (Dictyostelium discoideum)


name: 2,3-dinitrotoluene + NADH + O2 => 4-methyl-3-nitrocatechol + nitrite + NAD(+) + H(+)


name: P2Y5 receptor can bind to LPA (Rattus norvegicus)


name: STAP2 recruits STAT3 to PTK6 (Mus musculus)


name: DLST transfers succinyl to CoA (Homo sapiens)


name: MSH2:MSH6:ATP bound to U:G mismatch binds MLH1:PMS2 (Dictyostelium discoideum)


name: L-serine 2-dehydrogenase (NAD+) activity


name: PAK1-3 phosphorylates VE-cadherin (Sus scrofa)


name: PPO oxidises PPGEN9 to PRIN9 (Schizosaccharomyces pombe)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate <=> 9-(9Z-octadecenoyloxy)-octadecanoate + 1,3-di-(9Z-octadecenoyl)-glycerol


name: a 2-O-(alpha-D-mannosyl)-6-O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + CoA => a 2,6-O-bis(alpha-D-mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + an acyl-CoA


name: beta-cyclopiazonate + diphosphate => cyclo-acetoacetyl-L-tryptophan + dimethylallyl diphosphate


name: PTK6 phosphorylates KHDRBS1 (Mus musculus)


name: Phosphorylation of NBS1 by ATM (Gallus gallus)


name: Release of Cytochrome c from mitochondria (Sus scrofa)


name: erythromycin D + S-adenosyl-L-methionine = erythromycin B + S-adenosyl-L-homocysteine + H(+)


name: L-alanyl-L-glutamine + ADP + phosphate + H(+) => L-glutamine + L-alanine + ATP


name: ADP + ATP + H(+) => P(1),P(4)-bis(5'-adenosyl) tetraphosphate + phosphate


name: CHST8 transfers SO4(2-) from PAPS to glyco-Lutropin (Mus musculus)


name: a 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP-alpha-D-galactose => a 3-O-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc}-L-threonyl-[protein] + UDP + H(+)


name: HDAC1:2-containing complex binds HDAC2 Inhibitors (Saccharomyces cerevisiae)


name: tetracosanoate + ATP + CoA = tetracosanoyl-CoA + AMP + diphosphate


name: IL13:IL13RA:TYK2 binds IL4R:JAK2 (Homo sapiens)


name: D-phenylalanine + O2 + H2O <=> 3-phenylpyruvate + H2O2 + NH4(+)


name: 3-methyl-2-oxobutanoate + NAD(+) + CoA <=> 2-methylpropanoyl-CoA + CO2 + NADH


name: MAPK1,(MAPK3) phosphorylates NPAS4 (Homo sapiens)


name: Active RNA Pol II complex transcribes lesion-containing DNA template (Sus scrofa)


name: (9Z,12Z)-octadecadienoate + AH2 + O2 <=> (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O


name: EGFR phosphorylates EPS15 (Homo sapiens)


name: negative regulation of hemoglobin biosynthetic process


name: Formation of MSH2:MSH3 Complex (Bos taurus)


name: 5-O-[(E)-caffeoyl]-shikimate + H2O <=> shikimate + (E)-caffeate + H(+)


name: a 2,3-saturated acyl-[ACP] + NAD(+) => a (2E)-enoyl-[ACP] + NADH + H(+)


name: SLC31A1 transports Cu1+ from extracellular region to cytosol (Bos taurus)


name: Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Sus scrofa)


name: L-valine(out) + L-alanine(in) = L-valine(in) + L-alanine(out)


name: RNA polymerase III general transcription initiation factor activity


name: Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)


name: p-CD19:VAV binds PI3K and GRB2 (Mus musculus)


name: FAM20B phosphorylates Xyl moiety (Sus scrofa)


name: Phosphorylation of MEK4 by MEKK1 (Mus musculus)


name: Recruitment of U7 snRNP:ZFP100 complex to the SLBP Bound Pre-mRNA (Drosophila melanogaster)


name: XPC:RAD23:CETN2 and UV-DDB bind distorted dsDNA site (Danio rerio)


name: p-4Y-SIRPA:CD47 binds SKAP2 (Gallus gallus)


name: nitrous oxide + NADP(+) + H2O => 2 nitric oxide + NADPH + H(+)


name: Keratin filaments bind cell-cell adhesion complexes (Xenopus tropicalis)


name: CYP4F8 19-hydroxylates PGH2 (Mus musculus)


name: S1PR1 binds S1PR1 agonists (Mus musculus)


name: Exocytosis of secretory granule lumen proteins (Sus scrofa)


name: 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oate + ATP + CoA = 3-hydroxy-9-oxo-9,10-seco-chola-1,3,5-trien-22-oyl-CoA + AMP + diphosphate


name: 4-hydroxyphenylacetate + NADPH + O2 + H(+) <=> homogentisate + NADP(+) + H2O


name: carboxyphosphate + ADP => hydrogencarbonate + ATP


name: AKR1A1 reduces D-glucuronate to L-gulonate (Homo sapiens)


name: MARK4 binds ODF2 in the centriole (Rattus norvegicus)


name: CES1 trimer hydrolyses ACEI pro-drugs to ACEIs (Drosophila melanogaster)


name: ATM phosphorylates RBBP8 (Rattus norvegicus)


name: MST1R autophosphorylates (Gallus gallus)


name: Disassociation of Telomerase RNP and the Chromosome End (Mus musculus)


name: 2,4-dihydroxy 5,6-dimethylbenzaldehyde + AMP + diphosphate + NADP(+) => 5-methylorsellinate + ATP + NADPH + H(+)


name: 2-demethylmenaquinol-12 + S-adenosyl-L-methionine = menaquinol-12 + S-adenosyl-L-homocysteine + H(+)


name: mycinamicin III + S-adenosyl-L-methionine = mycinamicin IV + S-adenosyl-L-homocysteine + H(+)


name: P-type divalent copper transporter activity


name: Superoxide and nitric oxide react to form peroxynitrite in mitochondria (Homo sapiens)


name: UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Rattus norvegicus)


name: NME1:NME3 heterohexamer phosphorylates NDPs to NTPs (Homo sapiens)


name: (-)-10-hydroxycoronaridine + S-adenosyl-L-methionine <=> (-)-voacangine + S-adenosyl-L-homocysteine + H(+)


name: 2 Fe(III)-[cytochrome c2] + dimethyl sulfide + H2O => 2 Fe(II)-[cytochrome c2] + dimethyl sulfoxide + 2 H(+)


name: 2 (3R)-3-isocyanylbutanoyl-[ACP] + L-lysine + ATP + 2 NADPH => (2S)-2,6-bis[(3R)-3-isocyanobutanamido]hexan-1-ol + 2 holo-[ACP] + AMP + diphosphate + 2 NADP(+)


name: TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Caenorhabditis elegans)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Xenopus tropicalis)


name: 6-deoxocastasterone + reduced [NADPH--hemoprotein reductase] + O2 => 6alpha-hydroxycastasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: EXO1 excises single strand DNA surrounding a U:G mismatch (Dictyostelium discoideum)


name: Furin cleaves pro-factor VII to factor VII (Canis familiaris)


name: (-)-minovincinine + acetyl-CoA => (-)-echitovenine + CoA


name: PSPH:Mg2+ dimer dephosphorylates O-P-Ser (Drosophila melanogaster)


name: MITF-M-dependent CCNB1 gene expression (Homo sapiens)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Drosophila melanogaster)


name: 16alpha,17beta-estriol 3-O-(beta-D-glucuronate)(in) + ATP + H2O => 16alpha,17beta-estriol 3-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)


name: alpha-D-Glc-(1->3)-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP-L-glycero-beta-D-manno-heptose <=> alpha-D-Glc-(1->3)-[L-alpha-D-Hep-(1->7)]-L-alpha-D-Hep-(1->3)-4-O-PO3(2-)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)


name: a medium-chain 2,3-saturated fatty acyl-CoA + O2 <=> a medium-chain (2E)-enoyl-CoA + H2O2


name: (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + malonyl-CoA + H(+) => (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + CoA


name: CPT1B transfers PALM to CAR (Mus musculus)


name: Sustained activation of SRC kinase by SHP2 (Homo sapiens)


name: Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Saccharomyces cerevisiae)


name: positive regulation of calcium-mediated signaling


name: Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Homo sapiens)


name: uracil + FMNH2 + NADH + O2 <=> (Z)-3-ureidoacrylate + FMN + NAD(+) + H2O + H(+)


name: (E)-feruloyl-CoA + 2-oxoglutarate + O2 => (E)-6-hydroxyferuloyl-CoA + succinate + CO2


name: fenbendazole + reduced [NADPH--hemoprotein reductase] + O2 = fenbendazole S-oxide + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Dictyostelium discoideum)


name: (E,E)-feruperate + reduced [NADPH--hemoprotein reductase] + O2 <=> (E,E)-piperate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: (4aR,7S)-2-(adenosyl(5')diphospho(5)ribosyl)-7-amino-4-carbamoyl-4a,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-7-carboxylate + 2-oxoglutarate + O2 <=> (4aR,6S,7R)-2-(adenosyl(5')diphospho(5)ribosyl)-6-hydroxy-7-amino-4-carbamoyl-4a,5,6,7-tetrahydro-2H-cyclopenta[c]pyridine-7-carboxylate + succinate + CO2


name: alpha-methylacetoacetyl-CoA + CoA => propionyl-CoA + acetyl-CoA (Rattus norvegicus)


name: an N-(1,2 saturated very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) <=> an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base + 2 Fe(III)-[cytochrome b5] + H2O


name: TGFB1,TGFB2 bind TGFBR3 (Canis familiaris)


name: Recruitment of dystrophin, dystrobrevin and syntrophin proteins to the DGC (Mus musculus)


name: RISC binds inexactly matching target RNAs (Sus scrofa)


name: UXS1 tetramer decarboxylates UDP-glucuronate to UDP-xylose (Rattus norvegicus)


name: an alpha-D-Kdo-(2->4)-alpha-D-Kdo-(2->6)-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate => an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + di-trans,octa-cis-undecaprenyl diphosphate


name: GLI:SUFU translocates to the ciliary tip in response to Hh signaling (Danio rerio)


name: PKCdelta phosphorylates HuR (Mus musculus)


name: HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)


name: D-proline(in) + H(+)(in) => D-proline(out) + H(+)(out)


name: N-(15Z-tetracosenoyl)-sphing-4-enine + cholesteryl 3-beta-D-glucoside => beta-D-glucosyl-(1<->1')-N-(15Z-tetracosenoyl)-sphing-4-enine + cholesterol


name: 1D-myo-inositol hexakisphosphate + H2O => 1D-myo-inositol 1,2,3,5,6-pentakisphosphate + phosphate


name: (R)-cembrene A + diphosphate => (2E,6E,10E)-geranylgeranyl diphosphate


name: sCD163 binds MYH9 in T-cells (Homo sapiens)


name: guaiacol + S-adenosyl-L-methionine => veratrole + S-adenosyl-L-homocysteine + H(+)


name: SPIDR binds BLM:TOP3A:RMI1:RMI2 (Bos taurus)


name: (2E)-geraniol + acetyl-CoA <=> (2E)-geranyl acetate + CoA


name: Newly Formed Phosphodiester Bond Stabilized and PPi Released (Danio rerio)


name: AMBRA1 binds DYNLL1,DYNLL2 (Danio rerio)


name: ALK mutants:p-3Y SHC binds GRB2 (Homo sapiens)


name: PGLS hydrolyzes D-glucono-1,5-lactone 6-phosphate (Caenorhabditis elegans)


name: (2R,9S)-annullatin H + A <=> (2R)-annullatin F + AH2


name: Hyperpolarization-activated Cyclic Nucleotide-gated Channel Antagonists


name: ZFP36 (Tristetraproline, TTP) binds AU-rich elements in 3' UTR of target mRNAs (Homo sapiens)


name: I(1,3,4,5)P4 transports from the cytosol to the nucleus (Drosophila melanogaster)


name: LTA4H:Zn2+ hydrolyses 7S(8)-epoxy-17(R)-HDHA to AT-RvD1 or AT-RvD2 (Bos taurus)


name: pentachlorophenol + NADPH + O2 + H(+) <=> 2,3,5,6-tetrachloro-1,4-benzoquinone + chloride + NADP(+) + H2O


name: Xaa-L-Pro dipeptide + H2O = an L-alpha-amino acid + L-proline


name: CREB3L2 translocates from the cytosol to the nucleus (Homo sapiens)


name: 2-hexadecanoylglycerol + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine => 1-(9Z)-octadecenoyl-2-hexadecanoylglycerol + (9Z-octadecenoyl)-sn-glycero-3-phosphocholine


name: (2E)-eicosenoyl-CoA + NADH + H(+) = eicosanoyl-CoA + NAD(+)


name: Initial resection of double-strand break ends (Bos taurus)


name: Formation of neural BAF (nBAF) (Homo sapiens)


name: The phagophore extends from the PIP3-enriched structure (Saccharomyces cerevisiae)


name: ISGylation of DDX58 (RIG-I) (Rattus norvegicus)


name: RHOJ GAPs stimulate RHOJ GTPase activity (Caenorhabditis elegans)


name: a 2'-deoxyuridine in single-stranded DNA + H2O = a 2'-deoxyribose 5'-monophosphate in single-stranded DNA + uracil


name: p-Y-IRS1,p-Y-IRS2 bind PI3K (Rattus norvegicus)


name: NUMB:ITCH ubiquitinates GLI1 (Rattus norvegicus)


name: N-decanoyl-(2S)-hydroxyglycine = decanamide + glyoxylate


name: BTK in G alpha (12)-BTK complex is activated (Bos taurus)


name: an N-(1-deoxy-beta-D-fructopyranos-1-yl)amine + O2 + H2O <=> (1-deoxy-D-fructos-1-yl)amine + an aldehyde + H2O2


name: Trypsin cleaves REG3A or REG3G to generate REG3A,G(38-175) (Gallus gallus)


name: 16beta,17beta-estriol + UDP-alpha-D-glucuronate = 16beta,17beta-estriol 3-O-(beta-D-glucuronate) + UDP + H(+)


name: SULT dimers sulfate APAP to APAP-SO3 (Gallus gallus)


name: PTCH is internalized (Rattus norvegicus)


name: GLUT4 (SLC2A4) tetramer transports Glc from extracellular region to cytosol (Rattus norvegicus)


name: CD151 interacts with BP180 and the integrin alpha 6 subunit (Sus scrofa)


name: Desaturation of tetracosatetraenoyl-CoA to tetracosapentaenoyl-CoA (Canis familiaris)


name: (R)-4'-phosphopantetheine + adenosine 3',5'-bisphosphate + 2 H(+) => CoA + H2O


name: phosphocholine + CMP + 2 H(+) => CDP-choline + H2O


name: (3R)-hydroxytriacontanoyl-CoA + NAD(+) <=> 3-oxo-triacontanoyl-CoA + NADH + H(+)


name: acetoacetyl-CoA + L-isoleucine + ATP => tenuazonic acid + AMP + diphosphate + CoA + 2 H(+)


name: 2'-deoxyinosine + phosphate = 2-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine


name: D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate   <=> xylulose 5-phosphate + D-erythrose 4-phosphate (Xenopus tropicalis)


name: FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Plasmodium falciparum)


name: cholesta-5,7-dien-3beta,24S-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => 7-dehydrocholesterol + reduced [NADPH--hemoprotein reductase] + O2


name: MTA2-NuRD complex deacetylates TP53 (Danio rerio)


name: a 3-demethylubiquinol + NAD(+) => a 3-demethylubiquinone + NADH + 2 H(+)


name: trimethylsulfonium + S-adenosyl-L-homocysteine => dimethyl sulfide + S-adenosyl-L-methionine


name: (4R)-hydroxysphinganine + hexadecanoyl-CoA <=> N-hexadecanoyl-(4R)-hydroxysphinganine + CoA + H(+)


name: (2E)-eicosenoyl-CoA + reduced [electron-transfer flavoprotein] => eicosanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+)


name: USP43 binds ISG:K164,ISG:K168-PCNA (Mus musculus)


name: SORD oxidizes D-sorbitol to Fru (Saccharomyces cerevisiae)


name: nucleoside triphosphate diphosphatase activity


name: ALK fusion proteins bind PLCG1 (Homo sapiens)


name: abscisate(in) + ATP + H2O => abscisate(out) + ADP + phosphate + H(+)


name: adenosine(37) in tRNA(Ala) + H2O + H(+) => inosine(37) in tRNA(Ala) + NH4(+)


name: lactose(out) + H(+)(in) => lactose(in) + H(+)(out)


name: Auto-ubiquitination of TRAF6 (Rattus norvegicus)


name: Active ALK phosphorylates JAK3 (Homo sapiens)


name: abscisate(out) + ADP + phosphate + H(+) => abscisate(in) + ATP + H2O


name: thymidine + phosphate => 2-deoxy-alpha-D-ribose 1-phosphate + thymine


name: SLC35A1 exchanges CMP-Neu5Ac for CMP (Danio rerio)


name: Ubiquitinated SMAD4 translocates from the nucleus to the cytosol (Drosophila melanogaster)


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + ATP = beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-O-P-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + ADP


name: Abortive initiation after formation of the first phosphodiester bond (Danio rerio)


name: dihydrosanguinarine + NADP(+) <=> sanguinarine + NADPH


name: 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C (Homo sapiens)


name: dihydroprecondylocarpine acetate (enamine form) = dehydrosecodine + acetate + H(+)


name: quercetin 3-O-beta-D-glucoside + UDP-alpha-D-glucose => quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP + H(+)


name: RAS intrinsic GTPase activity hydrolyzes GTP to GDP (Dictyostelium discoideum)


name: The p75NTR:NgR:MDGI complex reduces RHOA-GDI activity, displacing RHOA (Homo sapiens)


name: Neuromedin-U receptors bind neuromedins U, S (Bos taurus)


name: a N-[omega-(9R,10R)-epoxy-13-oxo-(11E)-octadecenoyloxy]acyl-beta-D-glucosyl-(1<->1)-sphing-4E-enine + NADH + H(+) => a N-[omega-(9R,10R)-epoxy-(13R)-hydroxy-(11E)-octadecenoyloxy]acyl-beta-D-glucosyl-(1<->1)-sphing-4E-enine + NAD(+)


name: 3-methylbut-2-enoyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] <=> 3-methyl-(2E)-glutaconyl-CoA + N(6)-biotinyl-L-lysyl-[protein]


name: activation of PERK signaling in response to endoplasmic reticulum stress


name: K63polyUb-cIAP1,2 ubiquitinates TRAF3 (Bos taurus)


name: mRNA9 is translated to Nucleoprotein (Homo sapiens)


name: 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + L-serine = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoserine + ethanolamine


name: 3-(4-hydroxyphenyl)pyruvate + CO2 + NADPH => prephenate + NADP(+)


name: protein quality control for misfolded or incompletely synthesized proteins


name: ent-isokaurene + reduced [NADPH--hemoprotein reductase] + O2 => ent-isokauren-2beta-ol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: 3-phosphoshikimate + phosphoenolpyruvate => 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate


name: Activated FGFR4 binds PLCG1 (Drosophila melanogaster)


name: L-Glutamate loading of synaptic vesicle (Caenorhabditis elegans)


name: ATG12 forms a thioester bond with ATG7 dimer (Dictyostelium discoideum)


name: Brevican degradation by ADAMTS4, ADAMTS5 (Sus scrofa)


name: SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) (Drosophila melanogaster)


name: CX3 complex binds D-loop structures (Bos taurus)


name: IMP + H2O + NAD+ => XMP + NADH + H+ [IMPDH1,2] (Rattus norvegicus)


name: CD200 binds to CD200R (Xenopus tropicalis)


name: PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Plasmodium falciparum)


name: glutathione disulfide + hydrogen sulfide + H(+) => S-sulfanylglutathione + glutathione


name: 3beta-hydroxy-5alpha-androstan-17-one + NADPH + H(+) = 5alpha-androstane-3beta,17beta-diol + NADP(+)


name: PTP1B binds the GH receptor complex (Homo sapiens)


name: mogroside IIIE + UDP-alpha-D-glucose => mogroside IV + UDP + H(+)


name: CYP3A4 monooxygenates ATVL to 4-OH-ATVL (Bos taurus)


name: 17beta-estradiol + reduced [NADPH--hemoprotein reductase] + O2 => 7alpha-hydroxy-17beta-estradiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)


name: NF-kappaB translocates from the cytosol to the nucleus (Rattus norvegicus)


name: L,L-cystathionine + phosphate => O-phospho-L-homoserine + L-cysteine


name: N-carbamoyl-L-methionine + H2O + 2 H(+) = L-methionine + NH4(+) + CO2


name: 17-hydroxy-(9Z,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2


name: N(4)-acetylcytosine + H2O = cytosine + acetate + H(+)


name: sucrose 6(F)-phosphate + H2O => sucrose + phosphate


name: PTPN22 dissociates from CSK (Canis familiaris)


name: PGG2 is reduced to PGH2 by PTGS2 (Canis familiaris)


name: EPS15 and HGS bind ubiquitinated MET (Canis familiaris)


name: glycolate(out) + (S)-malate(in) => glycolate(in) + (S)-malate(out)


name: (E)-1,3-pentadiene + CO2 => (E,E)-sorbate + H(+)


name: aminoacetaldehyde + CO2 => 2-aminomalonate semialdehyde + H(+)


name: Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)


name: 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + NH4(+) => 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(2-hydroxyethyl)-2-methylpyridinium + H2O + H(+)


name: DPF2, PHF10 bind SMARCC1:SMARCC2 dimer:SMARD1:ARID1A (Mus musculus)


name: PVR:PVRL3 trans heterodimer interaction (Danio rerio)


name: arginine + H2O => ornithine + urea [ARG1] (Rattus norvegicus)


name: PI(4,5)P2, PI(3,4)P2 and PI(3,4,5)P3 are dephosphorylated to PI5P, PI3P and PI(3,4)P by INPP5F at the endosome membrane (Rattus norvegicus)


name: 2-glutaroyl-sn-glycero-3-phosphocholine + hexadecanoate + H(+) => 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O


name: NMRK1 phosphorylates NR to yield NMN (Rattus norvegicus)


name: UBA1 conjugates ubiquitin to UBA1 in the cytosol (Danio rerio)


name: IP receptor can bind prostacyclin (Rattus norvegicus)


name: HMGCR dimer reduces bHMG-CoA to MVA (Bos taurus)


name: ATP13A2 transports cations from cytosol to lysosomal lumen (Sus scrofa)


name: N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(out) + n H(+)(out) <=> N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine(in) + n H(+)(in)


name: SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Gallus gallus)


name: 2 N-(3-carboxypropanoyl)-N-hydroxycadaverine + ATP <=> bisucaberin B + AMP + diphosphate + H(+)


name: LC3 binds the autophagosome membrane Atg5-Atg12 complex (Caenorhabditis elegans)


name: 5S-HpETE is dehydrated to LTA4 by ALOX5 (Bos taurus)


name: SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Bos taurus)


name: creatine + ATP => phosphocreatine + ADP [CK octamer] (Sus scrofa)


name: MTMR4 dephosphorylates SMAD2/3 (Mus musculus)


name: CHRM2,4 bind acetylcholine (Mus musculus)


name: Binding of TFIIE to the growing preinitiation complex (Schizosaccharomyces pombe)


name: (R)-5-diphosphomevalonate + H2O = (R)-5-phosphomevalonate + phosphate + H(+)


name: myo-inositol + NAD(+) = myo-inosose-5 + NADH + H(+)


name: pyrrolizixenacetamide + H2O <=> 3-amino-5,6,7,7a-tetrahydro-1H-pyrrolizin-1-one + acetate + H(+)


name: IL35 binds IL12RB2:IL12RB2 receptor (Homo sapiens)