name: Cyclin D:Cdk4/6 mediated phosphorylation of p130 (RBL2) and dissociation of phosphorylated p130 (RBL2) from DP1:E2F4/5 complex (Gallus gallus)


name: P(1),P(2)-bis(5'-adenosyl) diphosphate + H2O => 2 AMP + 2 H(+)


name: positive regulation of intrinsic apoptosis


name: G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Caenorhabditis elegans)


name: Activation of Protein Kinase C novel isoforms (Sus scrofa)


name: platelet activating factor receptor ligand


name: Loading and methylation of Sm proteins onto SMN Complexes (Mus musculus)


name: SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Bos taurus)


name: 5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Bos taurus)


name: KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate MeK10-histone H3 (Plasmodium falciparum)


name: (4Z)-tetradecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) <=> (2E,4Z)-tetradecadienoyl-CoA + reduced [electron-transfer flavoprotein]


name: SKI complexes with the Smad complex, suppressing BMP2 signalling (Gallus gallus)


name: (2R)-2-hydroperoxydodecanoate + H(+) = undecanal + CO2 + H2O


name: PIP3 recruits PDPK1 to the membrane (Mus musculus)


name: Formation of the inner ring of the 20S core particle of the 26S proteasome (Homo sapiens)


name: L-lactate dehydrogenase (cytochrome) activity


name: SCF-beta-TRCP binds p-7S-p100 in active NIK:p-S176,180-IKKA dimer:p-7S-p100:RELB (Drosophila melanogaster)


name: PDE12 cleaves 2'-5' oligoadenylates  (Bos taurus)


name: inhibition of acetylneuraminyl hydrolase activity


name: 5,6,7,8-tetrahydromethanopterin + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] <=> 5-methyl-5,6,7,8-tetrahydromethanopterin + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)


name: 7,8-dihydroneopterin 3'-triphosphate + H2O => 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H(+)


name: N(2)-(ADP-D-ribosyl)-dGMP + nicotinamide + H(+) => dGMP + NAD(+)


name: menaquinone-8 + L-aspartate => iminosuccinate + menaquinol-8


name: EXT1:EXT2 transfers GlcA to heparan (Sus scrofa)


name: 1D-myo-inositol 2-(L-cysteinylamino)-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA => mycothiol + CoA + H(+)


name: TBC1D3 associates with RAB5 (Drosophila melanogaster)


name: CXXC1 and WDR82 bind SET1A complex (Canis familiaris)


name: Formation of C4b:factor B complex (Gallus gallus)


name: poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends


name: a 3'-end uridylyl-uridine-RNA = a 3'-end 2',3'-cyclophospho-uridine-RNA + uridine


name: MOGAT1,2,3 transfer acyl group from acyl-CoA to 2-acylglycerol to form DAG (Drosophila melanogaster)


name: O-atom dealkylation of dextromethorphan (Dictyostelium discoideum)


name: cholate + L-serine => L-serocholate + H2O


name: tridecanal + CO2 + H2O => (2R)-2-hydroperoxytetradecanoate + H(+)


name: 7alpha-hydroxy-3,12-dioxo-5beta-cholanate + NADP(+) => dehydrocholate + NADPH + H(+)


name: cholate(in) + glutathione(in) + ATP + H2O => cholate(out) + glutathione(out) + ADP + phosphate + H(+)


name: phenol + FADH2 + O2 = catechol + FAD + H2O + H(+)


name: PIP3 binds to RhoA and activates it (Canis familiaris)


name: a neolactoside IV(3)-alpha-GalNAc,IV(2)-alpha-Fuc-nLc4Cer + H2O = a neolactoside IV(2)-alpha-Fuc-nLc4Cer + N-acetyl-alpha-D-galactosamine


name: keto-D-tagatose 6-phosphate <=> keto-D-fructose 6-phosphate


name: 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP <=> 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Bos taurus)


name: SAR1 Activation And Membrane Binding (Canis familiaris)


name: small conductance calcium-activated potassium channel inhibitor activity


name: 17-O-acetylnorajmaline + NADP(+) = (2R)-1,2-dihydrovomilenine + NADPH + 2 H(+)


name: hexanoyl-[ACP] + malonyl-[ACP] + H(+) => 3-oxooctanoyl-[ACP] + holo-[ACP] + CO2


name: lipid IVA 3-deoxy-D-manno-octulosonic acid transferase


name: CBX4 SUMOylates CBX4 in PRC1 with SUMO1 (Homo sapiens)


name: Caspase mediated cleavage of alpha-II-Fodrin (Mus musculus)


name: Nitric Oxide Synthase (NOS) produces Nitric Oxide (NO) (Bos taurus)


name: RGGT geranylgeranylates RAB proteins (Caenorhabditis elegans)


name: Displacement of SMUG1 glycosylase by APEX1 at the AP site (Mus musculus)


name: Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Bos taurus)


name: a 1,2-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine => a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine


name: Activation of CHEK1 at resected DNA DSBs (Canis familiaris)


name: HTRA2 binds NDUFA13 (GRIM-19) (Drosophila melanogaster)


name: ganglioside GD1a (18:1(4E)/18:0) + CMP + H(+) => ganglioside GM1 (d18:1(4E)/18:0) + CMP-N-acetyl-beta-neuraminate


name: 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + hexadecanoate + H(+)


name: (Z)-butanethial oxide => (E)-but-1-en-1-SO-peroxol


name: AAC1 imports a proton (Xenopus tropicalis)


name: UGT8 transfers Gal from UDP-Gal to CERA (Mus musculus)


name: Lamellar bodies bind the early cornified envelope (Bos taurus)


name: 8-oxo-dGTP + H2O <=> 8-oxo-dGMP + diphosphate + H(+)


name: Aquaporin-3 passively transports water out of cell (Bos taurus)


name: 2 nataloe emodin + reduced [NADPH--hemoprotein reductase] + O2 => cladofulvin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: alpha-D-mannose derivative + alpha-D-glucose 1-phosphate + H(+) => 6-(alpha-D-glucose-1-phospho)-alpha-D-mannosyl derivative + H2O


name: LONP1 binds mitochondrial matrix proteins (Mus musculus)


name: (3S)-hydroxy-(5Z-tetradecenoyl)-CoA + NAD(+) <=> 3-oxo-(5Z-tetradecenoyl)-CoA + NADH + H(+)


name: DHAP is converted to G3P by GPD1/GPD1L (Sus scrofa)


name: L-cysteine + L-glutamate + ATP <=> gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)


name: 3-phenylpropanal + AMP + diphosphate + NADP(+) => 3-phenylpropanoate + ATP + NADPH + H(+)


name: 5-hydroxy-4-(hydroxymethyl)-7-methoxy-6-methylphthalide + S-adenosyl-L-homocysteine + H(+) => 5,7-dihydroxy-4-(hydroxymethyl)-6-methylphthalide + S-adenosyl-L-methionine


name: beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphoenolpyruvate <=> 4,6-Me(COOH)C-beta-D-Man-(1->4)-beta-D-GlcA-(1->2)-alpha-D-Man-(1->3)-beta-D-Glc-(1->4)-alpha-D-Glc-di-trans,octa-cis-undecaprenyl diphosphate + phosphate


name: PIPOX oxidises PPCA to P6C (Canis familiaris)


name: methylarsonous acid + S-adenosyl-L-methionine => dimethylarsinate + S-adenosyl-L-homocysteine + 2 H(+)


name: PPP4C:PPP4R2 dephosphorylates RPA2 (Sus scrofa)


name: Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)


name: NOTCH1 PEST domain mutants bind HES1 promoter (Homo sapiens)


name: a ganglioside Ac-O-9-GT3 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine => a ganglioside Ac-O-9-GT2 (d18:1(4E)) + UDP + H(+)


name: VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Bos taurus)


name: prostaglandin H2 <=> (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde


name: EPOR binds EPOR agonists (Rattus norvegicus)


name: 1-O-(1Z-hexadecenyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoate + H(+)


name: dihydroxyacetone phosphate + glyceraldehyde 3-phosphate <=> fructose 1,6-bisphosphate (Gallus gallus)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycerol + phosphate


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Homo sapiens)


name: POM121 and NDC1 bind the Nup93 complex (Canis familiaris)


name: 2xPPCS ligates PPanK with Cys (Xenopus tropicalis)


name: a ganglioside SB1a (d18:1(4E)) + adenosine 3',5'-bisphosphate + H(+) => a ganglioside SM1b (d18:1(4E)) + 3'-phosphoadenylyl sulfate


name: D-ribulose 5-phosphate + ADP + H(+) => D-ribulose + ATP


name: Addition of the third nucleotide on the nascent HIV-1 transcript (Homo sapiens)


name: CA1:Zn2+,CA2:Zn2+ dehydrate HCO3- to CO2 (Sus scrofa)


name: tetracosanoyl-CoA + H2O <=> tetracosanoate + CoA + H(+)


name: FKBP1A binds sirolimus (Saccharomyces cerevisiae)


name: aldehydo-D-ribose 5-phosphate + L-lysyl-[protein] = N(6)-(5-O-phospho-D-ribulosyl)-L-lysyl-[protein] + H2O


name: N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + 4-methyl-2-oxopentanoate + malonyl-[ACP] + 2 H(+) = 5-methyl-3-oxohexanoyl-[ACP] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + 2 CO2


name: branched-chain 2-oxoacid:malonyl-[acyl-carrier protein] acyltransferase


name: a ganglioside GM2 + H2O <=> a ganglioside GA2 + N-acetylneuraminate


name: 3-hydroxypropanal + NAD(+) + H2O => 3-hydroxypropanoate + NADH + 2 H(+)


name: LARGE1,2 elongates matriglycan chain with GlcA (Bos taurus)


name: (2E)-geranyl diphosphate = (4S)-limonene + diphosphate


name: 1-hexadecanoyl-2-glutaroyl-sn-glycero-3-phosphocholine + H2O => glutarate + 1-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)


name: Activated NTRK3 binds SHC1 (Homo sapiens)


name: D-leucine + O2 + H2O <=> 4-methyl-2-oxopentanoate + H2O2 + NH4(+)


name: 5,6-dihydrouridine(47) in tRNA + NAD(+) <=> uridine(47) in tRNA + NADH + H(+)


name: (2E,6E)-farnesyl diphosphate + H2O = (5S,9S,10S)-drim-7-en-11-ol + diphosphate


name: Association between RAD9 and TopBP1 (Gallus gallus)


name: mRNA1 is translated to pp1ab (Homo sapiens)


name: SFTPD binds with itself to form SFTPD 12mer (Bos taurus)


name: AHCTF1 (ELYS) binds chromatin and Nup107-Nup160 complex (Homo sapiens)


name: Cleavage of uracil by TDG glycosylase (Canis familiaris)


name: S-methyl-5'-thioadenosine + H2O <=> 5-(methylsulfanyl)-D-ribose + adenine


name: pseudomonate C + ATP + CoA = pseudomonoyl-CoA C + AMP + diphosphate


name: NTPDase1 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)


name: Interaction of PECAM-1 and SHP-1 (Sus scrofa)


name: (9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2 <=> 11-hydroxy-(9Z,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: a (7Z,10Z,13Z,16Z)-docosatetraenoyl derivative + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = a (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl derivative + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: alpha-maltopentaose + phosphate => alpha-maltotetraose + alpha-D-glucose 1-phosphate


name: PGH2 is reduced to PGF2a by AKR1C3 (Rattus norvegicus)


name: 2-amino-4-oxopteridine-6-carbaldehyde + glycolaldehyde + H2O2 => D-erythro-neopterin + hnu + O2


name: Dissociation of phospho-Cdh1 from the APC/C complex (Danio rerio)


name: N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + H2O => N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + O2


name: Autophosphorylation of PDGF beta receptors (Sus scrofa)


name: octacosanoyl-CoA + 2 NADPH + 2 H(+) => octacosan-1-ol + 2 NADP(+) + CoA


name: Formation of ADAR2  homodimer (Sus scrofa)


name: Nuclear translocation of p38 MAPK (Caenorhabditis elegans)


name: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + ATP + CoA => (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + AMP + diphosphate


name: a 2-arylethylamine + acetyl-CoA <=> an N-acetyl-2-arylethylamine + CoA + H(+)


name: RGS proteins bind GNB5 and CCT/TRiC (Canis familiaris)


name: tRNA-specific adenosine deaminase activity


name: 3',5'-cyclic GMP(in) = 3',5'-cyclic GMP(out)


name: DVL1 is ubiquitinated by HECW1 (Canis familiaris)


name: decanal + NAD(+) + H2O <=> decanoate + NADH + 2 H(+)


name: CK2 phosphorylates condensin I subunits (Homo sapiens)


name: cholesterol + NADPH + O2 + H(+) = 7-dehydrocholesterol + NADP(+) + 2 H2O


name: 4-(3-methylbut-2-enyl)-L-tryptophan + S-adenosyl-L-methionine <=> 4-(3-methylbut-2-enyl)-L-abrine + S-adenosyl-L-homocysteine + H(+)


name: monacolin J + (S)-2-methylbutanoate + H(+) => lovastatin + H2O


name: N-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoate + H(+) => N-hexadecanoyl-1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O


name: Association of procollagen type XXVII (Homo sapiens)


name: a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + H2O <=> a 1-acyl-2-hexanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + phosphate


name: D-maltotetraono-1,5-lactone + H2O <=> D-maltotetraonate + H(+)


name: reduced [rubredoxin] + superoxide + 2 H(+) => oxidized [rubredoxin] + H2O2


name: raucaffrinoline + NADP(+) <=> perakine + NADPH + H(+)


name: (3R)-hydroxy-(13Z)-docosenoyl-CoA + NAD(+) = 3-oxo-(13Z)-docosenoyl-CoA + NADH + H(+)


name: 2-hydroxyglutarate + CoA + H(+) => propanoyl-CoA + glyoxylate + H2O


name: IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3:PI3K-regulatory subunits binds IRS1,IRS2 (Bos taurus)


name: PIAS1 binds p-STAT1 dimer (Gallus gallus)


name: Stalling of DNA replication fork and RPA binding (Bos taurus)


name: hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)


name: [4-(deca-1,8-diyl)-2,5-dioxo-2,5-dihydro-3-furanyl]acetate + 2 H2O => (4E,11E)-2-hydroxytrideca-4,11-dien-1,2,3-tricarboxylate + 2 H(+)


name: L-2,4-diaminobutanoate + acetyl-CoA <=> (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)


name: Phosphorylation of PKC-theta (Mus musculus)


name: Fibrillin microfibril assembly (Homo sapiens)


name: (6E)-8-hydroxygeranial + NADP(+) <=> (6E)-8-oxogeranial + NADPH + H(+)


name: hexadecanoyl-[ACP] + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => (4Z)-hexadecenoyl-[ACP] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O


name: hexanoyl-CoA + 3 malonyl-CoA + 3 H(+) = 3,5,7-trioxododecanoyl-CoA + 3 CO2 + 3 CoA


name: GLI2,3 are degraded by the proteasome (Dictyostelium discoideum)


name: SLCO2B1-3 transports BIL  from extracellular region (blood) to cytosol (hepatocyte) (Bos taurus)


name: MATK (CSK homologous kinase) binds phosphorylated ERBB2 (Gallus gallus)


name: PP2A-PPP2R2A dephosphorylates FOXM1 (Rattus norvegicus)


name: Nephrin binds NCK (Caenorhabditis elegans)


name: CX3 complex formation (Xenopus tropicalis)


name: GTP + AH2 + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + L-methionine + A + H(+)


name: (1R,2R,3S,8R,10R,11R,15S,16S)-3-(acetyloxy)-15-[(4R)-4-[(2S)-3,3-dimethyloxiran-2-yl]-1,4-dihydroxybutan-2-yl]-2,7,7,11,16-pentamethyl-5-oxo-6-oxatetracyclo[9.7.0.0(2,8).0(12,16)]octadec-12-en-10-yl acetate + reduced [NADPH--hemoprotein reductase] + O2 = (1R,2R,3S,8R,10R,11R,15S,16S)-3-(acetyloxy)-15-(1-hydroxy-4-oxobutan-2-yl)-2,7,7,11,16-pentamethyl-5-oxo-6-oxatetracyclo[9.7.0.0(2,8).0(12,16)]octadec-12-en-10-yl acetate + 2-methylpropanoate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)


name: p-Y753,Y759-PLCG2 hydrolyses PIP2 (Rattus norvegicus)


name: (2E,6E,10E)-geranylgeranyl diphosphate => (13E)-labda-7,13-dien-15-yl diphosphate


name: gamma-L-glutamyltyramine + [5-(aminomethyl)furan-3-yl]methyl diphosphate = (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate


name: N(6),N(6)-dimethyl-L-lysyl-[protein] + 2-oxoglutarate + O2 => N(6)-methyl-L-lysyl-[protein] + formaldehyde + succinate + CO2


name: a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O <=> 1-O-(1Z-alkenyl)-sn-glycerol + phosphoethanolamine + H(+)


name: octadecanoyl-AMP + holo-[(hydroxy)phthioceranic acid synthase] <=> octadecanoyl-[(hydroxy)phthioceranic acid synthase] + AMP + H(+)


name: protein phosphatase type 4 regulator activity


name: serotonin(out) + 2 H(+)(in) => serotonin(in) + 2 H(+)(out)


name: (7S)-marmesin + reduced [NADPH--hemoprotein reductase] + O2 <=> psoralen + acetone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: JMJD7 dimer hydroxlates a lysine residue of DRG1 (Canis familiaris)


name: dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H2O = 5-hydroxymethyl-dUMP + (6S)-5,6,7,8-tetrahydrofolate


name: (9Z)-tetradecenoyl-CoA + H2O => (9Z)-tetradecenoate + CoA + H(+)


name: PHF20 binds TP53 dimethylated on K370 and K382 (Xenopus tropicalis)


name: CPSF3 cleaves pre-mRNA at proximal 3'UTR PAS (Homo sapiens)


name: an archaeal dolichyl alpha-D-glucosyl phosphate + UDP-alpha-D-glucuronate = an archaeal dolichyl beta-D-glucuronosyl-(1->4)-alpha-D-glucosyl phosphate + UDP + H(+)


name: 2 Fe(II)-[leghemoglobin] + NADP(+) + H(+) => 2 Fe(III)-[leghemoglobin] + NADPH


name: 3beta-hydroxy-5alpha-androstan-11,17-dione + NADP(+) => 5alpha-androstan-3,11,17-trione + NADPH + H(+)


name: hydroquinone + UDP-alpha-D-glucose => hydroquinone O-beta-D-glucopyranoside + UDP + H(+)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Canis familiaris)


name: RNA(n) + UTP => RNA(n)-3'-uridine ribonucleotide + diphosphate


name: I(1,4)P2 is dephosphorylated to I4P by INPP1 in the cytosol (Mus musculus)


name: PRMT6 methylates histone H2A arginine-30 (H2AR29) (Danio rerio)


name: Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Mus musculus)


name: CTSL1 cleaves proHPSE (Xenopus tropicalis)


name: L-arginyl-[protein] + NAD(+) = ADP-riboxanated L-argininyl-[protein] + nicotinamide + NH4(+) + H(+)


name: D-fructose(out) + ATP + H2O <=> D-fructose(in) + ADP + phosphate + H(+)


name: (3S)-hydroxy-(9Z,12Z,15Z)-octadecatrienoyl-CoA + NAD(+) = 3-oxo-(9Z,12Z,15Z)-octadecatrienoyl-CoA + NADH + H(+)


name: Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Sus scrofa)


name: RAS guanyl-nucleotide exchange mediated by SOS1 in complex with GRB2 and p-Y349,350-SHC1:p-ERBB4 (Danio rerio)


name: Association of Cyclin A with the APC/C (Gallus gallus)


name: RHOQ translocates to the Golgi-associated vesicle membranes (Caenorhabditis elegans)


name: Activated FGFR4 binds PLCG1 (Sus scrofa)


name: 2 campesine B + reduced [NADPH--hemoprotein reductase] + O2 => campesine F + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: (+)-copalyl diphosphate <=> neoabietadiene + diphosphate


name: (S)-versiconol + NADP(+) <=> (2S-3S)-versiconal hemiacetal + NADPH + H(+)


name: cimicifugate K + CoA => (2R,3S)-piscidate + (E)-4-coumaroyl-CoA


name: WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Rattus norvegicus)


name: mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)


name: a 5'-end triphospho-(purine-ribonucleoside) in mRNA + GDP + H(+) => a 5'-end (5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + diphosphate


name: 2-methylbutanoyl-CoA + ethanol => ethyl 2-methylbutanoate + CoA


name: Spermidine  => N-acetylated spermidine (Rattus norvegicus)


name: DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Sus scrofa)


name: positive regulation of nu DNA polymerase activity


name: leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT1] (Danio rerio)


name: sphinga-(4E,8E)-dienine + hexadecanoyl-CoA => N-hexadecanoylsphinga-(4E,8E)-dienine + CoA + H(+)


name: PRC2 (EZH2) core complex methylates nucleosomes at CDH1 gene promoter (Rattus norvegicus)


name: L-histidyl-[ankyrin-repeat domain protein] + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-L-histidyl-[ankyrin-repeat domain protein] + succinate + CO2


name: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate + ATP = UDP-solosamine + ADP + phosphate + H(+)


name: (2R)-2-phosphoglycerate + ADP + H(+) => (R)-glycerate + ATP


name: a 2'-O-methylribonucleotide in RNA + S-adenosyl-L-homocysteine + H(+) => a ribonucleotide in RNA + S-adenosyl-L-methionine


name: 1-hexadecanoyl-2-(9-oxononanoyl)-sn-glycero-3-phosphocholine + NADPH + H(+) <=> 1-hexadecanoyl-2-(9-hydroxynonanoyl)-sn-glycero-3-phosphocholine + NADP(+)


name: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) => 5alpha-pregnane-3,20-dione + NADPH + H(+)


name: (S)-(-)-citronellol + NAD(+) => (S)-(-)-citronellal + NADH + H(+)


name: N-carbamoyl-L-aspartate + H(+) => L-5-carboxymethylhydantoin + H2O


name: beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-Gly)-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate + 2 glycyl-tRNA(Gly) = MurNAc-L-Ala-D-isoglutaminyl-L-Lys-(N(6)-tri-Gly)-D-Ala-D-Ala-diphospho-di-trans,octa-cis-undecaprenyl-GlcNAc + 2 tRNA(Gly) + 2 H(+)


name: Phosphorylation of Platelet Sec-1 (Gallus gallus)


name: androst-4-ene-3,17-dione + NADH + O2 + H(+) => 9alpha-hydroxy-androst-4-ene-3,17-dione + NAD(+) + H2O


name: L-prolyl-[protein] + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-prolyl-[protein] + succinate + CO2


name: a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H(+) <=> a 3-alkylbut-(2E)-enoyl-[ACP] + CO2


name: CASTOR1 homodimer binds L-arginine and dissociates from GATOR2 (Bos taurus)


name: VAV1 is a GEF for Rho/Rac family GTPases (Drosophila melanogaster)


name: (9Z,12Z)-octadecadienoate + O2 => (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate


name: maltose + H2O => 2 D-glucose (sucrase-isomaltase) (Rattus norvegicus)


name: ENPP7 hydrolyzes sphingomyelin (Sus scrofa)


name: PDE3B hydrolyses cAMP to AMP (Bos taurus)


name: phosphonoacetaldehyde + NAD(+) + H2O <=> phosphonoacetate + NADH + 2 H(+)


name: IL35 binds IL6ST:IL6ST receptor (Bos taurus)


name: pro-defensin alpha 5 is secreted (Homo sapiens)


name: a beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer(d18:1(4E)) + UDP-alpha-D-galactose = an isogloboside iGb3Cer (d18:1(4E)) + UDP + H(+)


name: DDAH1 hydrolyses ADMA to DMA and L-Cit (Mus musculus)


name: PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Mus musculus)


name: L-threonine(out) + L-alanine(in) = L-threonine(in) + L-alanine(out)


name: MUC20 binds MET and inhibits GRB2 binding (Canis familiaris)


name: an ultra-long-chain fatty acyl-CoA + a sphingoid base = an N-(ultra-long-chain-acyl)-sphingoid base + CoA + H(+)


name: HSPG2 (perlecan) binds alpha-dystroglycan (Caenorhabditis elegans)


name: NSDHL decarboxylates 4a-carboxy-5a-cholest-8-ene-3b-ol to 5a-cholest-8-en-3-one (Mus musculus)


name: SCUBE1, SCUBE3 oligomerize (Homo sapiens)


name: ARV1 transports CHOL from ER membrane to plasma membrane (Sus scrofa)


name: FUT1 transfers Fuc to Type 2 chains to form H antigen-RBC (Homo sapiens)


name: wogonin + UDP-alpha-D-glucuronate <=> wogonin 7-O-beta-D-glucuronate + UDP


name: cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication


name: RPE dimers isomerise RU5P to XY5P (Plasmodium falciparum)


name: 1-(9Z,12Z)-octadecadienoylglycerone 3-phosphate + hexadecanoate => 1-hexadecanoylglycerone 3-phosphate + (9Z,12Z)-octadecadienoate


name: D-alanyl-[D-alanyl-carrier protein] + 3 malonyl-CoA + 2 H(+) => (8R)-2,4-dihydroxy-8-methyl isoindolinone + holo-[D-alanyl-carrier protein] + 3 CO2 + 3 CoA + H2O


name: (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 <=> 11-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoate


name: pregnenolone sulfate(out) + n H(+)(out) => pregnenolone sulfate(in) + n H(+)(in)


name: biotinate sulfoxide + NADH + H(+) => biotin + NAD(+) + H2O


name: PDE6 hydrolyses cGMP to GMP (Bos taurus)


name: I(1,3,4,6)P4 is dephosphorylated to I(3,4,6)P3 by ITPK1 in the cytosol (Rattus norvegicus)


name: histamine + beta-alanine => carcinine + H2O


name: S-methylmercury-L-cysteine(out) + L-methionine(in) = S-methylmercury-L-cysteine(in) + L-methionine(out)


name: very long-chain fatty acid-CoA ligase activity


name: GBP1:GBP2:GBP3:GBP4 forms higher-order structures (Gallus gallus)


name: factor X -> factor Xa + factor X activation peptide (VIIIa:IXa catalyst) (Bos taurus)


name: Fibrillin-1 degradation by MMP3, CTSK, CTSL2 (Homo sapiens)


name: Increased Spinal Cord Nitric Oxide Activity


name: PTCH1 inhibits accumulation of SMO in the primary cilium in the absence of Hh signal (Gallus gallus)


name: Phosphorylated STATs are released (Bos taurus)


name: HEXB cleaves the terminal GalNAc from DS (Caenorhabditis elegans)


name: Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Xenopus tropicalis)


name: uracil(out) + H(+)(out) => uracil(in) + H(+)(in)


name: Progressive trimming of alpha-1,2-linked mannose residues from Man8GlcNAc2 to produce Man5GlcNAc2 (Sus scrofa)


name: 17alpha-estradiol + NADP(+) <=> estrone + NADPH + H(+)


name: Clathrin internalises EPH:EFN complexes (Gallus gallus)


name: activation of amyloid structure formation


name: p62:MEKK3 binds to TRAF6 (Canis familiaris)


name: 1-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA <=> 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA


name: HGSNAT oligomer acetylates Heparan sulfate chain(3) (Bos taurus)


name: 3,3'-diiodo-L-thyronine sulfate + iodide + A + H(+) = 3,3',5'-triiodo-L-thyronine sulfate + AH2


name: SUCLG1/A2 cleaves succinyl-CoA (Mus musculus)


name: (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + 2 NADP(+) => 6-pyruvoyl-5,6,7,8-tetrahydropterin + 2 NADPH + 2 H(+)


name: SPOP-mediated degradation of CD274 by 26S Proteosome (Gallus gallus)


name: N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine + H(+) => L-lysyl-[histone] + S-adenosyl-L-methionine


name: HSP110s exchange ATP for ADP on HSP70s:ADP (Schizosaccharomyces pombe)


name: NTPDase1 hydrolyzes nucleoside diphosphates (Xenopus tropicalis)


name: PANK1/3 phosphorylate PanK (Xenopus tropicalis)


name: 2 3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + 2 O2 + H(+) <=> grixazone B + CO2 + 4 H2O


name: glycerol 2-phosphate(in) + ADP + phosphate + H(+) => glycerol 2-phosphate(out) + ATP + H2O


name: L-2-aminohexanoate + kynurenate + H2O => 2-oxohexanoate + L-kynurenine


name: AUF1(hnRNP D0) dimers bind AU-rich element in 3' UTR of mRNA (Danio rerio)


name: 1,3-dihexadecanoyl-2-(9Z-octadecenoyl)glycerol + H2O <=> 1,3-dihexadecanoylglycerol + (9Z)-octadecenoate + H(+)


name: ((1,6)-alpha-glucosyl)poly((1,4)-alpha-glucosyl)glycogenin => poly{(1,4)-alpha-glucosyl} glycogenin + alpha-D-glucose (Homo sapiens)


name: melibiose(in) + H(+)(in) => melibiose(out) + H(+)(out)


name: Mitochondrial uptake and processing of ALAS1 (Gallus gallus)


name: H2O2 oxidises ferrohemoglobin to MetHb (Sus scrofa)


name: SAR1 Activation And Membrane Binding (Drosophila melanogaster)


name: (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O


name: Cleaved fragments of DFF45 dissociate from  DFF40 (Canis familiaris)


name: (S)-3-hydroxyisobutanoyl-CoA + H2O <=> (S)-3-hydroxy-2-methylpropanoate + CoA + H(+)


name: STON2 binds SYT proteins (Caenorhabditis elegans)


name: APC/C:Cdh1-mediated degradation of Skp2 (Dictyostelium discoideum)


name: methylazoxymethanol + UDP-alpha-D-glucose <=> cycasin + UDP + H(+)


name: L-2-aminoadipate + ATP + NADPH + H(+) => (S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP(+)


name: De novo formation of eIF2:GTP (Caenorhabditis elegans)


name: pre-VLDL binds lipids to form VLDL (Rattus norvegicus)


name: Receptor-mediated uptake of HA (Sus scrofa)


name: NUDT18 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Xenopus tropicalis)


name: (9Z)-hexadecenoyl-CoA + sn-glycerol 3-phosphocholine = (9Z-hexadecenoyl)-sn-glycero-3-phosphocholine + CoA


name: HYKK phosphorylates 5HLYS (Xenopus tropicalis)


name: Interaction of Tie2 and Shc1 (Gallus gallus)


name: Butanoyl-CoA+FAD => Crotonoyl-CoA+FADH2 (Sus scrofa)


name: (3S)-3-methyl-L-phenylalanine + 2-oxoglutarate => (3S)-2-oxo-3-phenylbutanoate + L-glutamate


name: cytidine(34) in elongator tRNA(Met) + acetate + ATP = N(4)-acetylcytidine(34) in elongator tRNA(Met) + AMP + diphosphate


name: 3-oxo-triacontanoyl-CoA + NADPH + H(+) = (3R)-hydroxytriacontanoyl-CoA + NADP(+)


name: Interleukin-12 binds Interleukin-12 receptor (Homo sapiens)


name: an N,N,N-trimethylornithine lipid + 3 S-adenosyl-L-homocysteine + 3 H(+) => an N(2)-[(3R)-3-(2-saturated-acyloxy)acyl]-L-ornithine lipid + 3 S-adenosyl-L-methionine


name: (R)-mandelate + NAD(+) => phenylglyoxylate + NADH + H(+)


name: RAB43 hydrolyses GTP (Schizosaccharomyces pombe)


name: PXLP-K314-GPT transaminates PYR to form L-Ala (Canis familiaris)


name: Formation of HIF:CBP:p300 complex at promoters (Caenorhabditis elegans)


name: phosphatidylcholine phospholipase C activity


name: SARS-CoV-2 nsp9 binds to 7SL RNA (Homo sapiens)


name: 4alpha-hydroxymethylzymosterol + 2 Fe(III)-[cytochrome b5] + H2O => 4alpha-methylzymosterol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: NEIL3 cleaves spiroiminodihydantoin (Sus scrofa)


name: AGMO cleaves alkylglycerol into fatty aldehyde and glycerol (Mus musculus)


name: a ceramide(in) + ATP + H2O = a ceramide(out) + ADP + phosphate + H(+)


name: K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Gallus gallus)


name: PTPN22 dephosphorylates ZAP70 (Rattus norvegicus)


name: SIRT4 cleaves lipoyl from DLAT (Bos taurus)


name: SEC4C,D bind GOSR2 and STX5 (Xenopus tropicalis)


name: L-tyrosine + reduced [NADPH--hemoprotein reductase] + O2 = L-dopa + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (9Z,12Z)-octadecadienoyl-CoA + H2O => (9Z,12Z)-octadecadienoate + CoA + H(+)


name: GGCX gamma-carboxylates PROS1(25-676) (pro-protein S) (Bos taurus)


name: SENP1,2,5 proteolytically process SUMO1 (Dictyostelium discoideum)


name: P4 bind PGR (in the HSP90 chaperone complex) (Rattus norvegicus)


name: Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Xenopus tropicalis)


name: ABCB1,ABCC2 transport ATVs from cytosol to extracellular region (Sus scrofa)


name: a ganglioside SM1b (d18:1(4E)) + 3'-phosphoadenylyl sulfate => a ganglioside SB1a (d18:1(4E)) + adenosine 3',5'-bisphosphate + H(+)


name: TNF-alpha inhibitors bind to TNF(1-233) trimer (Mus musculus)


name: ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Mus musculus)


name: phosphorylation of 2'-Deoxythymidine to dTMP (Mus musculus)


name: (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate => (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O


name: Formation of ChAHP complex (Canis familiaris)


name: a ubiquinol = 2 e(-) + a ubiquinone + 2 H(+)


name: chlorohydroquinone + O2 <=> 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H(+)


name: Association of Emi1 with Cdh1 (Danio rerio)


name: Formation of the inner ring of the 20S thymoproteasome core particle (Dictyostelium discoideum)


name: NAGLU hydrolyses heparan chain(2) (Mus musculus)


name: IL18:IL18R1 binds IL18RAP (Mus musculus)


name: 5-PP-IP5 is dephosphorylated to IP6 by NUDT(1) in the cytosol (Danio rerio)


name: ASAH2 hydrolyzes ceramide (plasma membrane) (Bos taurus)


name: DT A:B binds HBEGF and CD9 on the target cell surface (Homo sapiens)


name: REST recruits the BHC complex (Caenorhabditis elegans)


name: PDE5A dimer binds PDE5A inhibitors (Homo sapiens)


name: SEC4C,D bind GOSR2 and STX5 (Caenorhabditis elegans)


name: (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H(+) => (S)-2,3,4,5-tetrahydrodipicolinate + NADP(+) + H2O


name: acetyl-CoA transmembrane transporter activity


name: TDO tetramer dioxygenates L-Trp to NFK (Canis familiaris)


name: GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Canis familiaris)


name: D-fructose + D-glucose => D-glucono-1,5-lactone + D-sorbitol


name: mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)


name: 2 3-(4-hydroxyphenyl)pyruvate + 2 ATP + H2O = (2S)-2-(4-hydoxybenzyl)-3-(4-hydroxyphenyl)-2-furonol carboxylate + 2 AMP + 2 diphosphate + H(+)


name: p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Gallus gallus)


name: a D-alpha-amino acid + NH4(+) + CO2 => an N-carbamoyl-D-amino acid + H2O + 2 H(+)


name: (2E)-geranyl diphosphate => limonene + diphosphate


name: PIP3 recruits AKT to the membrane (Saccharomyces cerevisiae)


name: ZnT5 transports zinc into the golgi apparatus (Schizosaccharomyces pombe)


name: VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Danio rerio)


name: testosterone + NADP(+) => androst-4-ene-3,17-dione + NADPH + H(+)


name: Organic Anion Transporting Polypeptide 1B3 Inhibitors


name: I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Danio rerio)


name: HSP90:FKBP4:PTGES3 binds HSF1 trimer (Rattus norvegicus)


name: Trimming of peptides in ER (Caenorhabditis elegans)


name: Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Mus musculus)


name: Active NIK phosphorylates IKKA dimer (Homo sapiens)


name: MIB2-mediated K63-ubiquitination of CD274 (Gallus gallus)


name: a steroid 1,3-dione + AH2 => a 1-hydroxy-3-oxo steroid + A


name: (3E)-3,4-didehydrorhodopin + AH2 => rhodopin + A


name: (5'S,6'R)-C-glycyluridine + O2 = uridine-5'-carboxamide + CO2 + H2O


name: Internalization of gap junction plaques (Canis familiaris)


name: tetradecan-1-ol + hexadecanoyl-CoA = tetradecyl hexadecanoate + CoA


name: plasmodiophorol B => (13S)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate


name: thermospermine + S-methyl-5'-thioadenosine + H(+) => S-adenosyl 3-(methylsulfanyl)propylamine + spermidine


name: (9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + malonyl-CoA + H(+) => 3-oxo-(11Z,14Z,17Z,20Z)-hexacosatetraenoyl-CoA + CO2 + CoA


name: Inactivation of Myt1 kinase (Drosophila melanogaster)


name: 1,2-dihexanoyl-3-octadecanoylglycerol + CoA => 1,2-dihexanoylglycerol + octadecanoyl-CoA


name: SRD5A3 reduces polyprenal to dolichal (Dictyostelium discoideum)


name: CCNK:CDK12 binds RNA Pol II at DNA repair genes (Gallus gallus)


name: hexadecanoyl-[(hydroxy)phthioceranic acid synthase] + 7 (S)-methylmalonyl-CoA + 14 NADPH + 21 H(+) => C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase] + 7 CO2 + 14 NADP(+) + 7 CoA + 7 H2O


name: WWTR1 (TAZ) binds ZO-1 (TJP1) (Rattus norvegicus)


name: Translocation of TRAF6 to CBM complex (Xenopus tropicalis)


name: STAT6, NFATC2 (NFAT1), and NICD1,2 bind the GATA3 gene and cause displacement of repressor complexes (PRC1, RBPJ:NCOR) by activator complexes (MLL1, RBPJ:NICD1,2) (Homo sapiens)


name: PI(3,4)P2 is dephosphorylated to PI4P by TPTE2 at the Golgi membrane (Mus musculus)


name: Activation of MMP9 intermediate form by MMPs (Rattus norvegicus)


name: all-trans-(4S)-hydroxyretinoate + reduced [NADPH--hemoprotein reductase] + O2 <=> all-trans-(4S,16)-dihydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: butyl propanoate + CoA => butan-1-ol + propanoyl-CoA


name: PFKFKB dimer dephosphorylates fructose 2,6-bisphosphate (Xenopus tropicalis)


name: desmethyl-dehydrogriseofulvin + oxidized [NADPH--hemoprotein reductase] + 2 H2O => griseophenone B + reduced [NADPH--hemoprotein reductase] + O2 + H(+)


name: 5beta-cholestane-3alpha,7alpha-diol + reduced [NADPH--hemoprotein reductase] + O2 <=> 5beta-cholestane-3alpha,7alpha,25-triol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: positive regulation of nitrogen cycle metabolic process


name: Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)


name: 1-O-methyl-(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatrienoate => 1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2


name: L-threonyl-[protein] + FAD = FMN-L-threonyl-[protein] + AMP + H(+)


name: Formation of active mTORC1 complex (Xenopus tropicalis)


name: p-S407,Y641-STAT6 is dimerized (Rattus norvegicus)


name: Keratin type I/type II heterodimers form tetramers (Gallus gallus)


name: cis-trans-nepetalactol => (S)-8-oxocitronellyl enol


name: H2 + a menaquinone + 2 H(+)(in) = a menaquinol + 2 H(+)(out)


name: PTGFR binds PTGFR agonists (Mus musculus)


name: RAS guanyl nucleotide exchange mediated by the p-6Y- ERBB2 ECD mutants:EGF:p-6Y-EGFR:p-SHC1:GRB2:SOS1 (Homo sapiens)


name: 1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA => 1,2-di-(9Z-octadecenoyl)-glycerol + CoA


name: Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-[N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine]2} + H2O + H(+) = Fe(III)-{N-(2,3-dihydroxybenzoyl)-L-seryl-N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine} + N-(C-5-[deoxy-beta-D-glucosyl]-2,3-dihydroxybenzoyl)-L-serine


name: a CDP-1,2-diacyl-sn-glycerol + 1D-myo-inositol 3-phosphate => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + CMP + H(+)


name: lutein + O2 = (3R,6R)-3-hydroxy-10'-apo-alpha-carotenal + (3R)-hydroxy-beta-ionone


name: terminolic acid 28-O-beta-D-glucoside + UDP-alpha-D-glucose = terminolic acid 28-O-[beta-D-glucosyl-(1->6)-beta-D-glucoside] + UDP + H(+)


name: Active PLC-gamma1 dissociates from EGFR (Mus musculus)


name: 2-oxobutanoate + acetyl-CoA + H2O <=> (R)-2-ethylmalate + CoA + H(+)


name: 20S,25-dihydroxycholecalciferol + 2 oxidized [adrenodoxin] + H2O => 20S-hydroxycholecalciferol + 2 reduced [adrenodoxin] + O2 + 2 H(+)


name: RAC1 and CDC42 activate PAK2 (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate => alpha-selinene + diphosphate


name: Recruitment of RNA Polymerase I:RRN3 to the 45S pre-rRNA gene (Bos taurus)


name: nitroglycerin + NADH <=> 1,3-dinitroglycerol + nitrite + NAD(+)


name: Phosphorylation of SLP-76 by p-SYK (Canis familiaris)


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+) => a CDP-1,2-diacyl-sn-glycerol + myo-inositol


name: Viral stem-loop 5'-UTR RNA does not bind IFIT1 (Homo sapiens)


name: (2E)-but-2-enoyl-AMP + holo-[ACP] <=> (2E)-butenoyl-[ACP] + AMP + H(+)


name: Expression of S-methyl-5'-thioadenosine phosphorylase (Homo sapiens)


name: sulcatone + NADPH + O2 + H(+) => 4-methylpent-3-en-1-yl acetate + NADP(+) + H2O


name: IL6 gene produces IL6 protein (Homo sapiens)


name: Connexin 62 mediated neuronal gap junction communication (Bos taurus)


name: O-methyl-L-tyrosine + anthranilate + S-adenosyl-L-methionine + 2 ATP => (-)-4'-methoxycyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H(+)


name: 3-hydroxybenzyl alcohol + benzoyl-CoA => 3-hydroxy-benzyl benzoate + CoA


name: HEXA cleaves the terminal GalNAc from DS (Dictyostelium discoideum)


name: odorant binds Odorant Receptor:GNAL:GDP:GNB1:GNGT1 (Canis familiaris)


name: MMP14:TIMP2 binds proMMP2 (Xenopus tropicalis)


name: a (3S)-3-hydroxyacyl-CoA + NAD(+) => a 3-oxoacyl-CoA + NADH + H(+)


name: a mycoketide-CoA + 10 CO2 + 22 NADP(+) + 10 CoA + 11 H2O => a medium-chain fatty acyl-CoA + 5 (S)-methylmalonyl-CoA + 5 malonyl-CoA + 22 NADPH + 32 H(+)


name: HSD17B3-like proteins reducde ANDST to TEST (Bos taurus)


name: SEPHS2 phosphorylates H2Se to form SELP (Dictyostelium discoideum)


name: G protein-coupled opioid receptor activity


name: an alkane-alpha,omega-diamine + acetyl-CoA => an N-acetylalkane-alpha,omega-diamine + CoA + H(+)


name: TP53 binds the BCL2L14 gene (Homo sapiens)


name: FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + GTP => a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + AMP + H(+)


name: 17-dehydrostemmadenine + H2O => (16R)-deshydroxymethyl-stemmadenine + formate


name: PTK6 phosphorylates KHDRBS1 (Bos taurus)


name: inhibition of FAS ligand-Fas signaling pathway


name: Binding of Gbeta/gamma to GIRK/Kir3 channels (Canis familiaris)


name: an N-acetyl-beta-D-galactosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine <=> an N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-beta-D-galactosaminyl derivative + UDP + H(+)


name: (+)-premalbrancheamide + bromide + FADH2 + O2 = (+)-isomalbrancheamide C + FAD + 2 H2O


name: nonadecanoate + ATP + CoA => nonadecanoyl-CoA + AMP + diphosphate


name: a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CoA => a 1-acyl-sn-glycero-3-phospho-L-serine + an acyl-CoA


name: cob(I)yrinic acid a,c-diamide adenosyltransferase activity


name: Transfer of ubiquitin from E1 to E2 (Rattus norvegicus)


name: oxaloacetate transmembrane transporter activity


name: 26S proteosome degrades ODC holoenzyme complex (Sus scrofa)


name: AADAT transaminates 3HKYN to xanthurenate (Schizosaccharomyces pombe)


name: a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine <=> a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine


name: [DNA-directed RNA polymerase] + ATP <=> phospho-[DNA-directed RNA polymerase] + ADP + H(+)


name: Light stimulates opsin receptors (Sus scrofa)


name: (2R)-3-phosphoglycerate + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+)


name: ornithine (cytosolic) + citrulline (mitochondrial) => ornithine (mitochondrial) + citrulline (cytosolic) (Rattus norvegicus)


name: 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphocholine + H2O <=> (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + sn-glycerol 3-phosphocholine + H(+)


name: Interaction of Tie2 and Ang4 (Mus musculus)


name: CDP-alpha-D-abequose + NADP(+) => CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H(+)


name: sphinganine(in) + ATP + H2O = sphinganine(out) + ADP + phosphate + H(+)


name: DLD dimer dehydrogenates dihydrolipoyl (Mus musculus)


name: Addition of a second glucose to the N-glycan precursor by ALG8 (Rattus norvegicus)


name: glutamine-alpha-keto acid transaminase activity


name: p-Y407-YAP1 translocates from the cytosol to the nucleoplasm (Caenorhabditis elegans)


name: Activated protein C:PROCR binds F2R (Sus scrofa)


name: 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + H2O => 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoate + H(+)


name: myricetin + UDP-beta-L-rhamnose <=> myricetin 3-O-alpha-L-rhamnoside + UDP + H(+)


name: gamma-L-glutamyl-L-glutamyl-[protein] + H2O => L-glutamyl-[protein] + L-glutamate


name: a 5'-end adenosine-5'-diphospho-5'-ribonucleotide-tRNA(His) + GTP <=> a 5'-end triphospho-guanosine-ribonucleotide-tRNA(His) + AMP + H(+)


name: 1,4-alpha-glucan is converted to glucanotrehalose (Mycobacterium tuberculosis)


name: ATXN3 family cleave Ub chains (Plasmodium falciparum)


name: 1-(9Z,12Z-octadecadienoyl)-glycerol + (9Z)-octadecenoyl-CoA => 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA


name: (+)-isomalbrancheamide D + FAD + 2 H2O => (+)-isomalbrancheamide B + bromide + FADH2 + O2


name: IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Bos taurus)


name: (+)-(E)-beta-caryophyllene + H2O => (+)-caryolan-1-ol


name: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O => a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate


name: negative regulation of ubiquitin protein ligase activity


name: Formation of NR-NCOR Corepressor Complex (Homo sapiens)


name: (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + O2 => (5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate


name: (2E,6E)-farnesyl diphosphate <=> (+)-aristolochene + diphosphate


name: 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+) => 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADPH


name: 9alpha-copalyl diphosphate = (12E)-9alpha-labda-8(17),12,14-triene + diphosphate


name: p130 (RBL2) associates with MuvB to form DREAM complex (Sus scrofa)


name: (3R)-hydroxy-(13Z,16Z,19Z,22Z)-octacosatetraenoyl-CoA <=> (2E,13Z,16Z,19Z,22Z)-octacosapentaenoyl-CoA + H2O


name: prekallikrein:kininogen binds cell surface receptors  (Sus scrofa)


name: RABGGTA and RABGGTB bind (Rattus norvegicus)


name: PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Homo sapiens)


name: Phospholipid phosphatase 6 hydrolyses Presqualene diphosphate to presqualene monophosphate (Sus scrofa)


name: p130 (RBL2) binds Cyclin E/A:CDK2 (Mus musculus)


name: phenylethanolamine + S-adenosyl-L-methionine = N-methylphenylethanolamine + S-adenosyl-L-homocysteine + H(+)


name: Acetylation of glucosamine 6-phosphate to GlcNAc6P (Schizosaccharomyces pombe)


name: GAR + 10-Formyl-THF => FGAR + THF (Bos taurus)


name: nitrate + a quinol <=> a quinone + nitrite + H2O


name: Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Canis familiaris)


name: PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)


name: Reinsertion of L1 into the plasma membrane (Homo sapiens)


name: GRB2:p-4S-SOS1:p-Y-IRS1,p-Y-IRS2 dissociates (Rattus norvegicus)


name: Furin cleaves pro-protein S to protein S (Mus musculus)


name: rifamycin SV + NADH + O2 => rifamycin SV para-naphthoquinone carboxamide + NAD(+) + H2O


name: Phosphorylation of LIN52 component of MuvB by DYRK1A (Danio rerio)


name: FOXO3 translocates from the mitochondrial matrix to the nucleus (Bos taurus)


name: a ganglioside Fuc-GM1 + UDP-alpha-D-galactose = a ganglioside Fuc(Gal)-GM1 + UDP + H(+)


name: 3-methylquinoline + A + H2O <=> 3-methylquinolin-2(1H)-one + AH2


name: Initial activation of proMMP3 (Danio rerio)


name: N(6),N(6),N(6)-trimethyl-L-lysine + 2-oxoglutarate + O2 <=> (3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + succinate + CO2


name: protodeoxyviolaceinate + NADPH + O2 + H(+) = deoxyviolaceinate + NADP(+) + H2O


name: guanine(out) + ATP + H2O <=> guanine(in) + ADP + phosphate + H(+)


name: NOX2 generates superoxide from oxygen (Rattus norvegicus)


name: N,N-dimethyl-1,4-phenylenediamine + aniline + 2 NADP(+) = 4-(dimethylamino)azobenzene + 2 NADPH + 2 H(+)


name: kainate(out) + ADP + phosphate + H(+) => kainate(in) + ATP + H2O


name: (2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) <=> 3-(3,4-dihydroxyphenyl)pyruvate + NADH + H(+)


name: quinoline + A + H2O = quinolin-2(1H)-one + AH2


name: ST3GAL5 transfers NeuNAc to ceramides (Bos taurus)


name: Activated TRAF6:p-IRAK2 interacts with TAK1 complex (Rattus norvegicus)


name: TRAIL receptor-4 binds TRAIL receptor-1 or TRAIL receptor-2 (Mus musculus)


name: S-hexadecanoyl-N-acetylcysteamine + H2O = N-acetylcysteamine + hexadecanoate + H(+)


name: GLUT1:ATP tetramer dissociates to GLUT1 tetramer and 4xATP (Canis familiaris)


name: an N-(acyl)-sphingosylphosphocholine(out) + ADP + phosphate + H(+) => an N-(acyl)-sphingosylphosphocholine(in) + ATP + H2O


name: Activated FGFR1 binds FLRT1,2,3 (Xenopus tropicalis)


name: MIB2 ubiquitinates CYLD at K338, K530 (Gallus gallus)


name: C2CD3 binds the mother centriole (Gallus gallus)


name: (2E,6E)-farnesyl diphosphate = delta-cadinene + diphosphate


name: OAT2 and OAT4 mediate transport of sulphate conjugates (Rattus norvegicus)


name: PHF8 demethylates histone H4K20me1 (Sus scrofa)


name: 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA <=> 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA


name: cholesterol + D-glucose => cholesteryl 3-beta-D-glucoside + H2O


name: asperaculane D + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+) => dauca-4,7-diene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2


name: PXLP-K278-PHYKPL tetramer hydrolyses 5PHL (Bos taurus)


name: (3R)-hydroxyoctacosanoyl-CoA + NAD(+) => 3-oxooctacosanyol-CoA + NADH + H(+)


name: Activated FMNL3 binds G-actin (Gallus gallus)


name: (+)-T-muurolol + diphosphate => (2E,6E)-farnesyl diphosphate + H2O


name: benzoyl-CoA + 3 malonyl-CoA + 2 H(+) <=> 2,4,6-trihydroxybenzophenone + 3 CO2 + 4 CoA


name: UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Bos taurus)


name: a 1-O-octadecyl-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) => a 1-O-(1Z-octadecenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: succinyl-CoA + acetate = succinate + acetyl-CoA


name: (S)-ureidoglycolate + NADP(+) = N-carbamoyl-2-oxoglycine + NADPH + H(+)


name: 3-hydroxy-L-kynurenine + pyruvate <=> 4-(2-amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-alanine


name: vanillin + L-alanine => vanillylamine + pyruvate


name: ALDH8A1 oxidises 9cRAL to 9cRA (Xenopus tropicalis)


name: 2,6,10,14-tetramethylpentadecanoate + ATP + CoA <=> pristanoyl-CoA + AMP + diphosphate


name: [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate => [glutamine synthetase]-L-tyrosine + ADP


name: SYK autophosphorylates at the activated BCR (Mus musculus)


name: PIAS2-1 SUMOylates PARK7 with SUMO1 (Schizosaccharomyces pombe)


name: inosine + phosphate => alpha-D-ribose 1-phosphate + hypoxanthine


name: (E)-4-coumaroyl alcohol + NADP(+) <=> (E)-4-coumaraldehyde + NADPH + H(+)


name: (8Z,11Z,14Z)-eicosatrienoate + O2 <=> 11-hydroperoxy-(8Z,12E,14Z)-eicosatrienoate


name: choline(in) + H(+)(in) => choline(out) + H(+)(out)


name: alpha-D-Man-(1->6)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc + D-mannose => alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc + H2O


name: anaerobic carbon-monoxide dehydrogenase activity


name: carbon-monoxide dehydrogenase (ferredoxin) activity


name: REG3A,REG3G binds bacterial peptidoglycan (Xenopus tropicalis)


name: HERC2 facilitates UBE2N:UBE2V2 binding to RNF8 (Rattus norvegicus)


name: a ganglioside Ac-O-9-GD1a (d18:1(4E)) + CMP + H(+) => CMP-N-acetyl-9-O-acetyl-beta-neuraminate + a ganglioside GM1 (d18:1(4E))


name: (d)ADP + ADP <=> (d)AMP + ATP (AK1) (Plasmodium falciparum)


name: 3-oxo-(13Z)-docosenoyl-CoA + CoA => (11Z)-eicosenoyl-CoA + acetyl-CoA


name: Platelet glycoprotein IV:ligand (CD36:ligand) is endocytosed (Mus musculus)


name: p-aminobenzoyl-glutamate uptake permease activity


name: apo-[BtrI ACP] + CoA <=> holo-[BtrI ACP] + adenosine 3',5'-bisphosphate + H(+)


name: PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Drosophila melanogaster)


name: L-histidine + O2 + H2O => 3-(imidazol-5-yl)pyruvate + H2O2 + NH4(+)


name: KSRP recruits RNA degradation activities (Canis familiaris)


name: ESR-associated SRC autophosphorylates (Homo sapiens)


name: XYLB phosphorylates D-xylulose (Saccharomyces cerevisiae)


name: SLC39A1-4 transports Zn2+ from extracellular region to cytosol (Dictyostelium discoideum)


name: Binding of newly synthesized MHC class I heavy chain (HC) with calnexin (Canis familiaris)


name: D-ribose 5-phosphate => alpha-D-ribose 1-phosphate


name: 16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + UDP + H(+) => 16alpha,17beta-estriol + UDP-alpha-D-glucuronate


name: high-affinity iron ion transmembrane transport


name: sodium-transporting ATPase activity, rotational mechanism


name: RIPK3 is cleaved by CASP8 (Mus musculus)


name: Synthesis of PIP3 from PIP2 by PI3K (Homo sapiens)


name: DENND1s exchange GTP for GDP on RAB35 (Xenopus tropicalis)


name: SLC2A5 transports fructose from extracellular region to cytosol (Dictyostelium discoideum)


name: 2-dehydro-3-deoxy-D-arabinonate + H2O => D-ribonate


name: 4alpha-methyl-5alpha-cholest-8-en-3-one + NADPH + H(+) = 4alpha-methyl-5alpha-cholest-8-en-3beta-ol + NADP(+)


name: Phosphorylated PER binds to CLK (Drosophila melanogaster)


name: (indol-3-yl)acetate + ATP + CoA => (indol-3-yl)acetyl-CoA + AMP + diphosphate


name: Phosphorylated GYS1 catalyzes the polyglucosylation of oligoGlc-GYG1 (Sus scrofa)


name: 3-oxo-(6Z)-hexadecenoyl-CoA + CoA <=> (4Z)-tetradecenoyl-CoA + acetyl-CoA


name: Formation of TSC1:TSC2 complex (Rattus norvegicus)


name: Fusogenic activation of gp41 (Homo sapiens)


name: Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Homo sapiens)


name: NOX4, NOX5 reduce O2 to O2.- (Canis familiaris)


name: 4-hydroxybenzoate + NADH + O2 + 2 H(+) => hydroquinone + CO2 + NAD(+) + H2O


name: Activation of Ca2+ activated Potassium channels with large conductance (Danio rerio)


name: Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Caenorhabditis elegans)


name: (2E,6Z)-octadecadienoyl-CoA + H2O = (3S)-hydroxy-(6Z)-octadecenoyl-CoA


name: 2 dopamine + O2 => 2 dopamine quinone + 2 H2O


name: GABRR pentamers:GABA transports extracellular Cl- to cytosol (Canis familiaris)


name: 2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Drosophila melanogaster)


name: 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + H2O <=> 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoate + H(+)


name: transforming growth factor beta receptor binding


name: Autocleavage of ESPL1 (Separase) (Sus scrofa)


name: an N(3)-acetyl-2-deoxystreptamine antibiotic + CoA + H(+) => a 2-deoxystreptamine antibiotic + acetyl-CoA


name: RHOA, RHOB, RHOC and RAC1 bind PKN1, PKN2 or PKN3 (Canis familiaris)


name: cob(I)alamin-[corrinoid adenosyltransferase] + ATP <=> apo-[corrinoid adenosyltransferase] + adenosylcob(III)alamin + triphosphate


name: 1,2,3-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + H2O <=> 1,2-di-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-glycerol + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H(+)


name: Fibrillin C-terminal processing (Sus scrofa)


name: LIAS synthesizes lipoyl-GCSH (Drosophila melanogaster)


name: prostaglandin G2 => (5Z,8Z,11Z,14Z)-eicosatetraenoate + 2 O2


name: PRKDC phosphorylates DCLRE1C at DNA DSBs (Homo sapiens)


name: SS18-containing ATPase complex binds SMARCC1 dimer:SMARCD1:SMARCE1:SMARCB1:ARID1:DPF1,2,3 (Sus scrofa)


name: RHOA:GTP translocates to the ER membrane (Bos taurus)


name: N,N,N-trimethylglycyl-CoA + H2O = glycine betaine + CoA + H(+)


name: hexadecanal + NADP(+) <=> (2E)-hexadecenal + NADPH + H(+)


name: RAC2 translocates to the mitochondrial membrane (Dictyostelium discoideum)


name: Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs (Homo sapiens)


name: NUDT15 hydrolyses 8-oxo-dGDP to 8-oxo-dGMP (Homo sapiens)


name: Fromation of the preholoimmunoproteasome (Caenorhabditis elegans)


name: Exocytosis of specific granule lumen proteins (Schizosaccharomyces pombe)


name: 5-formimidoyltetrahydrofolate + 2 H(+) = (6R)-5,10-methenyltetrahydrofolate + NH4(+)


name: (2,5-ethylene furandicarboxylate)(n) + 2 H2O => (2,5-ethylene furandicarboxylate)(n-1) + 2,5-dicarboxyfuran + ethylene glycol + 2 H(+)


name: RGGT binds the RAB-binding subunit (Homo sapiens)


name: Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Xenopus tropicalis)


name: gibberellin A15 + 2-oxoglutarate + O2 = gibberellin A24 + succinate + CO2 + H2O


name: (-)-menthyl beta-D-glucoside + UDP + H(+) => (-)-menthol + UDP-alpha-D-glucose


name: SFKs phosphorylate VAV2,3 (Rattus norvegicus)


name: 3,3',5-triiodo-L-thyronine(in) + L-glutamate(out) => 3,3',5-triiodo-L-thyronine(out) + L-glutamate(in)


name: 1-O-hexadecyl-sn-glycero-3-phosphocholine + H2O = 1-O-hexadecyl-sn-glycerol + phosphocholine + H(+)


name: RP2 binds ARL3:GTP:UNC119B (Rattus norvegicus)


name: MDM2 ubiquitinates JMY (Rattus norvegicus)


name: 6-carboxyhexanoyl-CoA + L-alanine + H(+) <=> (8S)-8-amino-7-oxononanoate + CO2 + CoA


name: ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Sus scrofa)


name: 3-oxooctanoyl-CoA + NADPH + H(+) => (3R)-hydroxyoctanoyl-CoA + NADP(+)


name: ATP-dependent topological DNA co-entrapment activity


name: IDH2 dimer decarboxylates isocitrate (Bos taurus)


name: MKRN1 polyubiquitinates PTEN (Dictyostelium discoideum)


name: presqualene diphosphate + H2O => presqualene phosphate + phosphate + H(+)


name: Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)


name: PEX19 binds class I peroxisomal membrane proteins (Dictyostelium discoideum)


name: (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + O2 <=> (2E,6Z,9Z,12Z,15Z)-octadecapentaenoyl-CoA + H2O2


name: Cholecystokinin receptors bind cholecystokinin (Rattus norvegicus)


name: SIRT5 desuccinylates CPS1 (Homo sapiens)


name: TBC1D2A accelerates GTP hydrolysis by RAB7 (Homo sapiens)


name: Caspase-mediated cleavage of Etk (Mus musculus)


name: leukotriene C4 + H2O = leukotriene D4 + L-glutamate


name: Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate


name: SESN1,2,3 bind AMPK (Drosophila melanogaster)


name: D-maltoheptaono-1,5-lactone + H2O <=> D-maltoheptaonate + H(+)


name: hexadecanoyl-[ACP] + sn-glycerol 3-phosphate <=> 1-hexadecanoyl-sn-glycero-3-phosphate + holo-[ACP]


name: FGFR3c binds to FGF (Drosophila melanogaster)


name: (2E,6E)-farnesyl diphosphate => sesquisabinene A + diphosphate


name: (2E,6E,10E)-geranylgeranyl diphosphate <=> delta-araneosene + diphosphate


name: asperterpenoid A + reduced [NADPH--hemoprotein reductase] + O2 <=> asperterpenoid C + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: IL6:IL6R binds IL6ST:JAK1,JAK2,(TYK2) (Danio rerio)


name: ULK1 phosphorylates AMBRA1:BECN1 complex (Sus scrofa)


name: IRE1 binds IRE1 forming dimer (Gallus gallus)


name: (E)-cinnamoyl-CoA + (R)-3-phenyllactate => (R)-3-phenyllactoyl-CoA + (E)-cinnamate


name: thiamine diphosphate phosphatase activity


name: thiamine diphosphate + H2O = thiamine phosphate + phosphate + H(+)


name: The proteasome degrades the alanine-tailed K48-polyUb nascent peptide bound to LTN1:NEMF:TCF25:VCP hexamer (Homo sapiens)


name: a 2-(omega-methylsulfanyl)alkylmalate <=> a 3-(omega-methylsulfanyl)alkylmalate


name: IMP + L-aspartate + GTP => N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)


name: SSBP1 binds the displaced parental H strand (Sus scrofa)


name: SLC30A8 transports Zn2+ from cytosol to secretory granule (Gallus gallus)


name: TRAF6 binding leads to IRAK1:TRAF6 release (Sus scrofa)


name: p-S26-ANXA2 binds integrin alpha5:beta1 at the plasma membrane (Gallus gallus)


name: (6S)-5-methyl-5,6,7,8-tetrahydrofolate(in) + H(+)(in) => (6S)-5-methyl-5,6,7,8-tetrahydrofolate(out) + H(+)(out)


name: a monoacylglycerol + phosphate => a monoacyl-sn-glycero-3-phosphate + H2O


name: (2E)-geranyl diphosphate => (-)-beta-phellandrene + diphosphate


name: 2xENPP1 hydrolyzes FAD to FMN (Caenorhabditis elegans)


name: IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Sus scrofa)


name: L-tyrosyl-[glycogenin] + UDP-alpha-D-glucose <=> alpha-D-glucosyl-L-tyrosyl-[glycogenin] + UDP + H(+)


name: 4-O-[di(2R)-glycerylphospho]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CDP-L-ribitol <=> 4-O-[(D-ribitylphospho)(n)-di{(2R)-glycerylphospho}]-N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + n CMP + n H(+)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Xenopus tropicalis)


name: 3,5-dimethyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + S-adenosyl-L-homocysteine + H(+) => 3-methyl-1-oxo-2-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1,5-dihydrobenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile + S-adenosyl-L-methionine


name: N-carbamoyl-L-alanine + H2O + 2 H(+) = L-alanine + NH4(+) + CO2


name: 2'-deoxyinosine + phosphate <=> 2-deoxy-alpha-D-ribose 1-phosphate + hypoxanthine


name: 3R-hydroxy-(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + NAD(+) => 3-oxo-(6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + NADH + H(+)


name: ATAC spliceosome mediated 3' splice site cleavage, exon ligation (Rattus norvegicus)


name: PP2A dephosphorylates KSR1 (Homo sapiens)


name: IRE1 dimer autophosphorylates (Xenopus tropicalis)


name: SLC35A3 exchanges UDP-GlcNAc for UMP (Caenorhabditis elegans)


name: (3S)-hydroxyoctanedioyl-CoA + NAD(+) => 3-oxooctanedioyl-CoA + NADH + H(+)


name: beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans-octa-cis-decaprenol + UDP-alpha-D-galactofuranose => beta-D-galactofuranosyl-(1->5)-beta-D-galactofuranosyl-(1->4)-alpha-L-rhamnosyl-(1->3)-N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octa-cis-decaprenol + UDP + H(+)


name: Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Saccharomyces cerevisiae)


name: KIBRA (WWC1) binds LATS proteins (Bos taurus)


name: XPO1:BACH1:Hemes are transported out of the nucleus (Mus musculus)


name: a 5'-end (5'-triphosphoguanosine)-adenosine in mRNA + diphosphate => a 5'-end diphospho-adenosine in mRNA + GTP + H(+)


name: 2-MAG and DAG are transacylated to TAG by PNPLA2/3 (Sus scrofa)


name: (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-dopa => (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + O2


name: Dimerization of PERK (Xenopus tropicalis)


name: tetradecanoyl-CoA + glycine <=> N-tetradecanoylglycine + CoA + H(+)


name: Activated FGFR2:p-SHC1:GRB2:SOS1 activates RAS nucleotide exchange (Rattus norvegicus)


name: BH3 only proteins associate with and inactivate anti-apoptotic BCL-XL (Sus scrofa)


name: okaramine A + 2-oxoglutarate + O2 => okaramine E + succinate + CO2


name: SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes (Caenorhabditis elegans)


name: CYP11B2 oxidises 11DCORST to CORST (Sus scrofa)


name: positive regulation of cholesterol sequestration


name: RAS proteins are depalmitoylated (Mus musculus)


name: N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 6A1,2B2) + H2O = N(4)-(alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + beta-D-mannose


name: SNAPs and NSF hexamer bind cis-SNARE at the TGN (Mus musculus)


name: GPVI stimulates PI3K beta, gamma (Rattus norvegicus)


name: an ultra-long-chain fatty acyl-CoA + 2 NADPH + 2 H(+) => an ultra long-chain primary fatty alcohol + 2 NADP(+) + CoA


name: phosphate + NAD(+) = ADP-alpha-D-ribose 1''-phosphate + nicotinamide + H(+)


name: SRXN1 reduces hyperoxidized PRDX1 dimer (Gallus gallus)


name: androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 => 19-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: (3S,5S)-3,5-diaminohexanoate + NAD(+) + H2O = (5S)-5-amino-3-oxohexanoate + NH4(+) + NADH + H(+)


name: NPAS4 binds CDK5R1 gene promoter (Homo sapiens)


name: GLUT1 (SLC2A1) tetramer transports Glc from extracellular region to cytosol (Gallus gallus)


name: (4R)-hydroxysphinganine 1-phosphate = (2R)-hydroxyhexadecanal + phosphoethanolamine


name: FRS2 binds to active TrkA receptor (Homo sapiens)


name: GGCX gamma-carboxylates 3D-F10(32-179) (pro-factor X light chain) (Rattus norvegicus)


name: (2E)-decenoyl-[ACP] + NADPH + H(+) <=> decanoyl-[ACP] + NADP(+)


name: SUMOylation of MKL1 with SUMO1 (Homo sapiens)


name: JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 (Homo sapiens)


name: TTYH1 transports cytosolic Cl- to extracellular region (Rattus norvegicus)


name: The PIDDosome activates CASP2 (Rattus norvegicus)


name: ER calcium channels open in response to activated PKA (Xenopus tropicalis)


name: UBE2I, HDAC7 SUMOylate PML with SUMO1 (Dictyostelium discoideum)


name: COQ7:COQ9 octamer hydroxylates DMQ10H2 (Homo sapiens)


name: RAF phosphorylates MAP2K dimer (Homo sapiens)


name: deamination of 2'-Deoxycytidine to 2'-Deoxyuridine (Bos taurus)


name: Acetylation of SMC3 subunit of chromosomal arm associated cohesin by ESCO1 or ESCO2 (Dictyostelium discoideum)


name: PTPRF, PTPRS, PTPRD bind Liprins (Rattus norvegicus)


name: Photolytic cleavage and thermal isomerization of 7-dehydroCHOL (Homo sapiens)


name: Phosphorylation of LIMK-1 by PAK (Xenopus tropicalis)


name: methyl-Co(III)-[glycine betaine-specific corrinoid protein] + coenzyme M = Co(I)-[glycine betaine-specific corrinoid protein] + methyl-coenzyme M + H(+)


name: [methyl-Co(III) glycine betaine-specific corrinoid protein]--coenzyme M methyltransferase


name: a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT1] (Mus musculus)


name: O-(5'-uridylyl)-L-seryl-[protein] + diphosphate => L-seryl-[protein] + UTP


name: a 3-O-[beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP + H(+) => a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-alpha-D-galactose


name: 15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 => 15,20-dihydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: trans-4-hydroxy-L-proline(out) + L-threonine(in) + Na(+)(out) <=> trans-4-hydroxy-L-proline(in) + L-threonine(out) + Na(+)(in)


name: CYP4A11 omega-hydroxylates DDCX (Bos taurus)


name: ARL6:GTP and the BBSome target cargo to the primary cilium (Bos taurus)


name: Interaction of IQGAP1 with nephrin (Homo sapiens)


name: POFUT2 transfers fucose to TSR domain-containing proteins (Bos taurus)


name: Chemokine Receptor Type 4 Interactions [MoA]


name: COASY transfers an adenylyl group from ATP to PPANT (Mus musculus)


name: crosslinked fibrin multimer:tissue plasminogen activator (two-chain):plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (two-chain) + plasmin (Danio rerio)


name: LIFR:JAKs bind gp130:JAKs:CNTFR (Canis familiaris)


name: 3-oxo-(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoA + CO2 + CoA => (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA + malonyl-CoA + H(+)


name: Glucosylation of collagen propeptide hydroxylysines (Sus scrofa)


name: activation of protein transport into mitochondrial outer membrane


name: I-SMAD competes with SMAD2/3 for type I receptor (TGFBR1) (Canis familiaris)


name: VEGF-C,D bind to VEGFR3 leading to receptor dimerization (Rattus norvegicus)


name: 1-hexadecanoyl-sn-glycero-3-phosphate + H2O => 1-hexadecanoyl-sn-glycerol + phosphate


name: p-Y705-STAT3 dimer, p-Y641-STAT6 dimer translocate to nucleus (Canis familiaris)


name: KMT2A (MLL) binds RUNX1 (Canis familiaris)


name: Pre-snRNA is elongated and capped with 7-methylguanosine (Dictyostelium discoideum)


name: p-4Y-PLCG1 dissociates from activated FGFR1 (Caenorhabditis elegans)


name: A1 and A3 receptors bind adenosine (Canis familiaris)


name: Cyclin E/A:Cdk2-mediated  phosphorylation of p27/p21 (Mus musculus)


name: UROD decarboxylates URO3 to COPRO3 (Schizosaccharomyces pombe)


name: salicylaldehyde + NAD(+) + H2O <=> salicylate + NADH + 2 H(+)


name: Polyubiquitinated TRAF6 binds the TAK1 complex (Canis familiaris)


name: MVB Vesicle Formation (Dictyostelium discoideum)


name: LTD4 is converted to LTE4 by DPEP1/2 (Drosophila melanogaster)


name: L-fuconate + H(+) => L-fucono-1,5-lactone + H2O


name: 2-hydroxyheptadecanoyl-CoA + succinate + CO2 => heptadecanoyl-CoA + 2-oxoglutarate + O2


name: Aldolase tetramer cleaves F1,6PP (Mus musculus)


name: nonanal + NADP(+) + H2O => nonanoate + NADPH + 2 H(+)


name: (E)-ferulate + H2O = 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoate


name: AKR1B1 reduces Glc to D-sorbitol (Schizosaccharomyces pombe)


name: 1-O-18-methylnonadecyl (9Z)-octadecenoate + CoA => 18-methylnonadecan-1-ol + (9Z)-octadecenoyl-CoA


name: Downregulation of c-Kit signaling by SOCS6 (Homo sapiens)


name: Translocation of ERBB4s80 to the nucleus (Sus scrofa)


name: negative regulation of calcium ion binding


name: Autocatalytic activation of MMP3 (Danio rerio)


name: ATPase-coupled polar amino acid-transporter activity


name: Cargo Recognition And Sorting (Bos taurus)


name: inhibition of tetrapyrrole metabolic process


name: (24S)-24,25-epoxycucurbitadienol + H2O = (24R)-24,25-dihydroxycucurbitadienol


name: FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Xenopus tropicalis)


name: 3-oxo-(7Z,10Z)-hexadecadienoyl-CoA + CoA = (5Z,8Z)-tetradecadienoyl-CoA + acetyl-CoA


name: inhibition of pentadecane metabolic process


name: p-S158,221-HuR binds mRNA (Homo sapiens)


name: MID1IP1 binds THRSP (Xenopus tropicalis)


name: a D-alpha-amino acid + A + H2O => a 2-oxocarboxylate + AH2 + NH4(+)


name: PXLP-K341-GPT2 transaminates PYR to form L-Ala (Homo sapiens)


name: S-sulfanyl-L-cysteinyl-[protein] + [thioredoxin]-dithiol <=> [thioredoxin]-disulfide + L-cysteinyl-[protein] + hydrogen sulfide + H(+)


name: RBKS phosphorylates ribose to R5P (Rattus norvegicus)


name: norbaeocystin + 2 S-adenosyl-L-methionine => psilocybin + 2 S-adenosyl-L-homocysteine + 2 H(+)


name: negative regulation of plasma lipoprotein oxidation


name: premithramycin B-lactone + H2O <=> mithramycin DK + CO2


name: PAPSS1,2 transfer SO4(2-) group to ATP to form APS (Saccharomyces cerevisiae)


name: dodecanoyl-CoA + malonyl-CoA + H(+) <=> 3-oxotetradecanoyl-CoA + CO2 + CoA


name: Association of HMGB1/HMGB2 with chromatin (Saccharomyces cerevisiae)


name: MLXIPL:MLX binds ACLY gene promoter (Homo sapiens)


name: Receptor CCR10 binds CCL27 and 28 ligands (Bos taurus)


name: a 12-hydroxyjasmonate + 3'-phosphoadenylyl sulfate => a 12-sulfojasmonate + adenosine 3',5'-bisphosphate + H(+)


name: Dissociation of Phospho-Nlp from the centrosome (Mus musculus)


name: Translocation of activated BAD protein to mitochondria (Canis familiaris)


name: (2E,6E)-farnesal + NADPH + H(+) => (2E,6E)-farnesol + NADP(+)


name: glutathione S,S-dioxide + H2O = sulfite + glutathione + H(+)


name: Formation of ORC(1-5) complex (Xenopus tropicalis)


name: trans-Golgi Network Vesicle Scission (Caenorhabditis elegans)


name: PPA1 hydrolyzes pyrophosphate to orthophosphate (Mus musculus)


name: Increased Cerebral Cortex Nerve Growth Factor Activity


name: ME1 tetramer decarboxylates OA to PYR (Homo sapiens)


name: Release of CSK from SRC (Rattus norvegicus)


name: positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity


name: sphing-4-enine(in) + ATP + H2O = sphing-4-enine(out) + ADP + phosphate + H(+)


name: FBXL21:CUL1:SKP1:RBX1 ubiquitinylates phosphorylated CRY1,2 (Homo sapiens)


name: dehydroabietadienol + NADPH + O2 + H(+) = dehydroabietadienal + NADP(+) + 2 H2O


name: 4-guanidinobutanoate + NADH + 2 H(+) => 4-guanidinobutanal + NAD(+) + H2O


name: para-aminobenzoic acid metabolic process


name: trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP-N-acetyl-alpha-D-glucosamine <=> O-(N-acetyl-alpha-D-glucosaminyl)-trans-4-hydroxy-L-prolyl-[Skp1 protein] + UDP + H(+)


name: GALK1 phosphorylates Gal to Gal1P (Bos taurus)


name: myricetin + UDP-beta-L-rhamnose = myricetin 3-O-alpha-L-rhamnoside + UDP + H(+)


name: 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Canis familiaris)


name: eicosanoyl-CoA + FAD + H(+) <=> (2E)-eicosenoyl-CoA + FADH2


name: CDC42 translocates to the endoplasmic reticulum membrane (Xenopus tropicalis)


name: Bile salts and acids dissociate from ALB (Mus musculus)


name: p-cumate + NADH + O2 + H(+) = (2R,3S)-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+)


name: xanthurenate(out) + a dicarboxylate(in) = xanthurenate(in) + a dicarboxylate(out)


name: AVPR2 bind desmopressin (Rattus norvegicus)


name: Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Gallus gallus)


name: sulcatol + NAD(+) <=> sulcatone + NADH + H(+)


name: CYB5Rs reduce MetHb to HbA (Homo sapiens)


name: DIAPH1 binds RHOA:GTP (Rattus norvegicus)


name: factor XII + β-amyloid fibril:Zn2+ -> factor XII:β-amyloid fibril:Zn2+ (Homo sapiens)


name: Initial resection of double-strand break ends (Rattus norvegicus)


name: SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol (Bos taurus)


name: 2 a 1-acyl-sn-glycerol => glycerol + a 1,2-diacyl-sn-glycerol


name: a 2'-deoxyguanosine in DNA + glyoxal <=> an N(2)-(1-hydroxy-2-oxoethyl)-2'-deoxyguanosine in DNA


name: PPO oxidises PPGEN9 to PRIN9 (Danio rerio)


name: prefumagillin + NADPH + 2 O2 => fumagillin + acetaldehyde + NADP(+) + H2O


name: indole + reduced [NADPH--hemoprotein reductase] + O2 = indolin-2-one + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: Arachidonate is hydroxylated to 20-HETE by CYP(3) (Mus musculus)


name: (2S)-2,6-bis[(3R)-3-isocyanobutanamido]hexan-1-ol + holo-[peptidyl-carrier protein] + 2 holo-[ACP] + 2 NADP(+) => L-lysyl-[peptidyl-carrier protein] + 2 (3R)-3-isocyanylbutanoyl-[ACP] + 2 NADPH


name: Dissociation of phosphoribosyl pyrophosphate amidotransferase tetramer (Danio rerio)


name: IK1 binds the PTCRA gene promoter (Homo sapiens)


name: SUMOylation of NPM1 with SUMO1 (Rattus norvegicus)


name: (1S,2S)-pseudoephedrine + NAD(+) = (S)-2-methylamino-1-phenylpropan-1-one + NADH + H(+)


name: RIF1 and PAX1IP bind TP53BP1 at DNA DSBs (Homo sapiens)


name: Rheb in the MTORC1 complex hydrolyses GTP (Homo sapiens)


name: CAND1 binds CRL4 E3 ubiquitin ligase in the nucleus (Xenopus tropicalis)


name: 6-oxocampestanol + reduced [NADPH--hemoprotein reductase] + O2 <=> cathasterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: TP53BP1 recruits DCLRE1C to ATM (Sus scrofa)


name: (5R)-5-phosphooxy-L-lysine + H2O <=> (S)-2-amino-6-oxohexanoate + NH4(+) + phosphate


name: L-olivosyl-oleandolide + S-adenosyl-L-methionine => L-oleandrosyl-oleandolide + S-adenosyl-L-homocysteine + H(+)


name: Recruitment of TRAF6 to CBM complex by binding to MALT1 (Homo sapiens)


name: Degradation of PCSK9:LDLR:Clathrin-coated vesicle (Sus scrofa)


name: ME1 tetramer decarboxylates MAL to PYR (Sus scrofa)


name: butane + NADH + O2 + H(+) <=> butan-1-ol + NAD(+) + H2O


name: 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Danio rerio)


name: Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Drosophila melanogaster)


name: MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG (Sus scrofa)


name: ACP6 hydrolyses MYS-LPA (Dictyostelium discoideum)


name: decanoyl-CoA + malonyl-[ACP] + H(+) => 3-oxododecanoyl-[ACP] + CO2 + CoA


name: Activation of TWIK-related K+ channel (TREK) (Gallus gallus)


name: oleanolate + reduced [NADPH--hemoprotein reductase] + O2 => echinocystate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: alcohol-forming fatty acyl-CoA reductase activity


name: CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Rattus norvegicus)


name: calcidiol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O => calciol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+)


name: 1,N(2)-ethenoguanine + O2 + H2O = 2-oxo-ethenoguanine + H2O2


name: PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Bos taurus)


name: Phosphorylation of BRCA1-A complex at multiple sites by ATM (Rattus norvegicus)


name: quercitrin + UDP-beta-L-rhamnose => quercetin 3,7-bis-O-alpha-L-rhamnoside + UDP + H(+)


name: N-acetyl-L-isoleucine + H2O = L-isoleucine + acetate


name: syringate + (6S)-5,6,7,8-tetrahydrofolate <=> 3-O-methylgallate + (6S)-5-methyl-5,6,7,8-tetrahydrofolate


name: (S)-Hydroxybutanoyl-CoA+NAD => Acetoacetyl-CoA+NADH+H (Sus scrofa)


name: Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Rattus norvegicus)


name: Phosphorylation of IKK-beta by TAK1 (Canis familiaris)


name: SARS-CoV-1 M protein interacts with TRAF3 (Homo sapiens)


name: lathosterol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 7-dehydrocholesterol + 2 Fe(III)-[cytochrome b5] + 2 H2O


name: GRB2-1:SOS1 binds p-Y-SHC (Mus musculus)


name: methane biosynthetic process from 3-(methylthio)propionic acid


name: Phosphorylation of Cyclin A:Cdk2 at Tyr 15 (Canis familiaris)


name: 5-hydroxymethyluracil DNA N-glycosylase activity


name: 3 S-adenosyl-L-methionine = nicotianamine + 3 S-methyl-5'-thioadenosine + 3 H(+)


name: RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin) (Mus musculus)


name: epitestosterone 17-O-(beta-D-glucuronate)(in) + ATP + H2O = epitestosterone 17-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)


name: L-homocysteine + ATP => L-homocysteine thiolactone + AMP + diphosphate


name: Defective OPN1SW does not bind 11cRAL (Homo sapiens)


name: Ficolin-2 binds to molecular patterns on the target cell surface  (Mus musculus)


name: bisanhydrobacterioruberin + H2O => monoanhydrobacterioruberin


name: FABP5:atRA translocates from cytosol to nucleoplasm (Drosophila melanogaster)


name: Co-sirohydrochlorin + 2 H(+) = sirohydrochlorin + Co(2+)


name: (R)-4'-phosphopantetheine + H2O <=> (R)-pantetheine + phosphate


name: lochnericine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+) => (-)-tabersonine + reduced [NADPH--hemoprotein reductase] + O2


name: ANO6 exposes PS, PE on the platelet membrane (Xenopus tropicalis)


name: 2-deoxy-D-glucose + ATP => 2-deoxy-D-glucose 6-phosphate + ADP + H(+)


name: Thiosulfate can transfer its sulfur atom to glutathione (Sus scrofa)


name: RBBP6 activates CPSF complex (Danio rerio)


name: oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor


name: CUL3:RBX1 ubiquitinates KEAP1 (Canis familiaris)


name: inositol phosphorylceramide glucuronosyltransferase activity


name: SARS-CoV-2 S binds SFTPD 12mer (Homo sapiens)


name: 5-O-(1-carboxyvinyl)-3-phosphoshikimate <=> chorismate + phosphate


name: Inactivation of PLC beta (Gallus gallus)


name: a 3-alkylbut-(2E)-enoyl-[ACP] + CO2 => a 4-carboxy-3-alkylbut-(2E)-enoyl-[ACP] + H(+)


name: TGFBR2 recruits TGFBR1 (Rattus norvegicus)


name: (2E,13Z,16Z,19Z,22Z,25Z)-octacosahexaenoyl-CoA + NADPH + H(+) = (13Z,16Z,19Z,22Z,25Z)-octacosapentaenoyl-CoA + NADP(+)


name: 1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate => 9-(9Z-octadecenoyloxy)-octadecanoate + 1,3-di-(9Z-octadecenoyl)-glycerol


name: riboflavin + NADH + 2 H(+) => reduced riboflavin + NAD(+)


name: oxalate(out) + sulfate(in) => oxalate(in) + sulfate(out)


name: positive regulation of glucose catabolic process to lactate via pyruvate


name: Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Homo sapiens)


name: DCXR tetramer reduces L-xylulose to xylitol (Caenorhabditis elegans)


name: Estrogen-independent phosphorylation of ESR1 S118 by MAPK1 and MAPK3 (Homo sapiens)


name: N(omega),N(omega)-dimethyl-L-arginine + glyoxylate => 5-(3,3-dimethylguanidino)-2-oxopentanoate + glycine


name: glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ (GLUD1,2) (Rattus norvegicus)


name: glutaredoxin (oxidized) + glutathione (reduced) => glutaredoxin (reduced) + glutathione (oxidized) (Danio rerio)


name: all-trans-4-oxoretinal + NADH + H(+) => all-trans-4-oxoretinol + NAD(+)


name: 2-oxo-3-sulfanylpropanoate + glycine => L-cysteine + glyoxylate


name: a 2'-deoxyribonucleoside 5'-phosphate + dTTP => a 2'-deoxyribonucleoside 5'-diphosphate + dTDP


name: an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UDP-N-acetyl-alpha-D-glucosamine = an N,N'-diacetylchitobiosyl-diphospho-di-trans,poly-cis-dolichol + UDP + H(+)


name: 2-dehydro-3-deoxy-L-arabinonate => glycolaldehyde + pyruvate


name: chromatin-nuclear membrane anchor activity


name: Ferritin Complex oxidises 4Fe2+ to Fe(3+)O(OH) (Bos taurus)


name: Endonucleolytic RISC hydrolyzes target RNAs (Rattus norvegicus)


name: NMRK1 phosphorylates NAR to yield NAMN (Xenopus tropicalis)


name: Association of Emi1 with Cdc20 (Xenopus tropicalis)


name: 2-methylpropanal + NH4(+) + NADH + H(+) => 2-methylpropan-1-amine + NAD(+) + H2O


name: 16S rRNA (guanine(966)-N(2))-methyltransferase activity


name: Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Homo sapiens)


name: PSD-95 binds NMDA receptor (Rattus norvegicus)


name: IL19 binds IL20RA:JAK1:IL20RB (Homo sapiens)


name: TNF:TNFR1 binds TRADD, TRAF2 and RIPK1 (Homo sapiens)


name: SEMA4D interacts with Plexin-B1:ErbB2 (Caenorhabditis elegans)


name: Mitochondrial recruitment of Drp1 (Drosophila melanogaster)


name: Phosphorylation of NTAL by p-SYK/Lyn (Rattus norvegicus)


name: xylitol + NAD(+) <=> D-xylulose + NADH + H(+)


name: CCNA:CDK1 phosphorylates HJURP (Mus musculus)


name: 17-beta-hydroxysteroid dehydrogenase (NAD+) activity


name: 3-O-(beta-D-glucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose => 3-O-[alpha-D-xylosyl-(1->3)-beta-D-glucosyl]-L-seryl-[EGF-like domain protein] + UDP + H(+)


name: 15S-HpETE is reduced to 15S-HETE by GPX1/2/4 (Homo sapiens)


name: ACO2 isomerizes citrate (Dictyostelium discoideum)


name: GLYAT-like proteins transfer glycine to aminobenzoyl-CoA (Canis familiaris)


name: Sulfate is exported to the cytosol in exchange for dicarboxylate (Dictyostelium discoideum)


name: Hydron translocation linked to the hydrolysis of diphosphate


name: Autocatalytic activation of proMMP13 (Sus scrofa)


name: Caspase-3 cleaves pro-interleukin-16 (Canis familiaris)


name: RhBG mediates ammonium effflux out of kidney collecting duct cells (Danio rerio)


name: L-cysteinyl-[NO transferase protein] + N(omega)-hydroxy-L-arginine + O2 => S-nitroso-L-cysteinyl-[NO transferase protein] + L-citrulline + H2O + H(+)


name: E-cadherin degradation by MMP3, MMP7 and plasmin (Homo sapiens)


name: PNPLA4 hydrolyzes retinyl palmitate (Xenopus tropicalis)


name: Activation of RAC1 by VAV (Drosophila melanogaster)


name: 4,4-dimethylcholesta-8(9),14,24-trien-3beta-ol is reduced to 4,4-dimethylcholesta-8(9),24-dien-3beta-ol [LBR] (Dictyostelium discoideum)


name: trans,octa-cis-decaprenylphospho-beta-D-arabinofuranose + NAD(+) = trans,octa-cis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + NADH + H(+)


name: Interaction of PECAM-1 and SHP-2 (Homo sapiens)


name: N-terminal L-cysteinyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-cysteinyl-[protein] + CoA + H(+)


name: (R)-lactate + a quinone => a quinol + pyruvate


name: chlorohydroquinone + 2 glutathione <=> hydroquinone + glutathione disulfide + chloride + H(+)


name: 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus (Bos taurus)


name: Caspase-1 active tetramer formation (Bos taurus)


name: IDS hydrolyses Heparan sulfate chain(5) (Rattus norvegicus)


name: N(alpha)-methyl-L-tryptophan + S-adenosyl-L-homocysteine + H(+) => L-tryptophan + S-adenosyl-L-methionine


name: UDP/CysLT receptor can bind cysteinyl leukotrienes (Homo sapiens)


name: L-cysteinyl-[protein] + an acyl-CoA => an S-acyl-L-cysteinyl-[protein] + CoA


name: 9-hydroxy-octadecanoate + a 1,2-diacyl-sn-glycerol = 9-(acyloxy)-octadecanoate + a 2-acylglycerol


name: SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Danio rerio)


name: (E)-4-oxonon-2-en-1-ol + NADP(+) <=> (E)-4-oxonon-2-enal + NADPH + H(+)


name: (+)-piperitol + reduced [NADPH--hemoprotein reductase] + O2 => (+)-sesamin + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)


name: beta-D-fructose 1,6-bisphosphate + H2O <=> beta-D-fructose 6-phosphate + phosphate


name: RAC1 and CDC42 activate PAK1 (Mus musculus)


name: Nephrin dimer:KIRREL binds FYN (Rattus norvegicus)


name: hexyl acetate + CoA => hexan-1-ol + acetyl-CoA


name: SCF(beta-TrCP) ubiquitinates p-GLI1 (Rattus norvegicus)


name: taurine + hexadecanoyl-CoA <=> N-hexadecanoyl-taurine + CoA + H(+)


name: Activation of PAKs by RAC1 and CDC42 (Dictyostelium discoideum)


name: Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Canis familiaris)


name: Formation of the Spliceosomal C complex containing intron lariat (Caenorhabditis elegans)


name: PRC2 recruits DNA methyltransferases (Homo sapiens)


name: Translocation of Cdc25B to the cytoplasm (Dictyostelium discoideum)


name: TGFBR2 phosphorylates TGFBR1 (Sus scrofa)


name: 2 glutathione + O2 <=> glutathione disulfide + H2O2


name: Rv3364c binds cathepsin G (Homo sapiens)


name: GEFs activate RhoA,B,C (Caenorhabditis elegans)


name: L-methionine(out) + chloride(out) + 2 Na(+)(out) <=> L-methionine(in) + chloride(in) + 2 Na(+)(in)


name: coproporphyrin III(out) + ADP + phosphate + H(+) => coproporphyrin III(in) + ATP + H2O


name: N-terminal L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester + hexadecanoyl-CoA <=> N-terminal N-hexadecanoyl-L-cysteinyl-[protein]-C-terminal glycyl cholesterol ester + CoA + H(+)


name: metoxuron + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) => 3-(3-chloro-4-methoxylphenyl)-1-methylurea + formaldehyde + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O


name: Canstatin binds integrins alphaVbeta3, alphaVbeta5 (Rattus norvegicus)


name: 4-hydroxybenzyl alcohol + 2 oxidized [azurin] => 2 reduced [azurin] + 4-hydroxybenzaldehyde + 2 H(+)


name: 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Rattus norvegicus)


name: 20-methylheneicosan-1-ol + (9Z)-octadecenoyl-CoA = 1-O-20-methylheneicosyl (9Z)-octadecenoate + CoA


name: DAG and Ca+2 bind to PKC and tether it to membrane (Saccharomyces cerevisiae)


name: β-blockers bind ADRB1,2,3 (Homo sapiens)


name: (R)-glycerate + NADP(+) => 3-hydroxypyruvate + NADPH + H(+)


name: HRH1 binds HRH1 inverse agonists (Homo sapiens)


name: 3-hydroxypropanoate + ATP + CoA = 3-hydroxypropanoyl-CoA + ADP + phosphate


name: SHMT1 tetramer transfers hydroxymethyl group to THFPG to form 5,10-methylene-THFPG (Canis familiaris)


name: Thrombin-activated PARs:G12/13 (active) dissociate (Mus musculus)


name: 7-oxolithocholate + NADPH + H(+) => chenodeoxycholate + NADP(+)


name: Fibrillin-1 degradation by MMP14 (Caenorhabditis elegans)


name: Formation of cap binding complex (CBC) (Xenopus tropicalis)


name: miltiradiene + diphosphate => (+)-copalyl diphosphate


name: Chloride ion and N-acyl group react to chloramide (Homo sapiens)


name: NAGLU hydrolyses Heparan sulfate chain(4) (Canis familiaris)


name: 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + reduced [NADPH--hemoprotein reductase] + O2 => 1-[(9S,10R)-epoxy-octadecanoyl]-sn-glycero-3-phosphocholine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)


name: GGT dimers hydrolyse APAP-SG (Rattus norvegicus)


name: CDKN1B is phosphorylated in response to estrogen (Sus scrofa)


name: A + NH4(+) + H2O = hydroxylamine + AH2 + H(+)


name: GLYCTK phosphorylates DGA to 3PDGA (Homo sapiens)


name: Association of Emi1 with Cdh1 (Canis familiaris)


name: NDUF subunits bind to form the FP subcomplex (Homo sapiens)


name: dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Rattus norvegicus)


name: LIPG dimer hydrolyzes HDL-associated TAG to DAG and LCFA (Canis familiaris)


name: BDH2 dehydrogenates 3HBA (Rattus norvegicus)


name: C5AR1 binds C5AR1 antagonist (Bos taurus)


name: PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Rattus norvegicus)


name: DNMT3A binds Me2sR4-HIST1H4 (Mus musculus)


name: TBK1 is phosphorylated within TBK1:OPTN:Ub-mitochondrial proteins (Sus scrofa)


name: Integrin alphaIIb beta3 activation (Caenorhabditis elegans)


name: 1,4-alpha-glucan branching enzyme activity


name: GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NH4(+) => 2-GDP-(2S,3S,6R)-3-hydroxy-5-imino-6-methyloxane + H2O


name: a ribonucleoside 5'-triphosphate + formate + H(+) = a 2'-deoxyribonucleoside 5'-triphosphate + CO2 + H2O


name: IKKB phosphorylates SNAP23 (Homo sapiens)


name: (E)-sinapate + choline + H(+) => O-sinapoylcholine + H2O


name: Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol (Homo sapiens)


name: pro-beta-NGF homodimer transits to the golgi apparatus (Homo sapiens)


name: Activated NOD oligomer recruites RIP2 (RICK) (Bos taurus)


name: (11Z)-eicosenoyl-CoA + O2 <=> (2E,11Z)-eicosadienoyl-CoA + H2O2


name: (1R,2R)-3-chlorocyclohexa-3,5-diene-1,2-diol + NAD(+) => chlorobenzene + NADH + O2 + H(+)


name: L-isoleucine + 2-oxoglutarate + O2 => 3(1)-hydroxy-L-isoleucine + succinate + CO2


name: activation of ergot alkaloid biosynthetic process


name: a 5'-hydroxy-3'-methoxyflavone + S-adenosyl-L-methionine = a 3',5'-dimethoxyflavone + S-adenosyl-L-homocysteine + H(+)


name: emodin + H2O + H(+) => emodin anthrone + O2


name: Stalled 55S mitochondrial ribosome is dissociated to yield 28S subunit and 39S subunit:mRNA:peptidyl-tRNA:tRNA (Homo sapiens)


name: complement receptor mediated signaling pathway


name: L-arginine + glycine = guanidinoacetate + L-ornithine


name: 2-hydroxydocosanoate + 2 Fe(III)-[cytochrome b5] + H2O => docosanoate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+)


name: L-threonyl-[protein] + FAD <=> FMN-L-threonyl-[protein] + AMP + H(+)


name: RNF5 and RNF185 ubiquitinate misfolded CFTR (Homo sapiens)


name: (7R)-7-(5-carboxy-5-oxopentanamido)deacetylcephalosporanate + D-glutamate => cephalosporin C + 2-oxoglutarate


name: a di-trans,poly-cis-dolichal + NADH + H(+) => a di-trans,poly-cis-dolichol + NAD(+)


name: aldehydo-N-acetyl-D-mannosamine + ATP => aldehydo-N-acetyl-D-mannosamine 6-phosphate + ADP + H(+)


name: 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 2-oxoglutarate + 2 O2 <=> 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 succinate + 2 CO2 + H2O


name: (2E)-triacontenoyl-CoA + NADPH + H(+) <=> triacontanoyl-CoA + NADP(+)


name: LTA4H:Zn2+ hydrolyses 16S,17S-epoxy-DHA to (N)PD1 (Saccharomyces cerevisiae)


name: WNT:FZD complex promotes G-protein nucleotide exchange (Canis familiaris)


name: SMPD1 hydrolyzes SPHM (Xenopus tropicalis)


name: Collagen type III degradation by MMP14 (Rattus norvegicus)


name: [phosphate](n-1) + D-glucose 6-phosphate + H(+) => [phosphate](n) + D-glucose


name: (R)-3,5-bisphosphomevalonate + H(+) = isopentenyl phosphate + CO2 + phosphate


name: Activation of JAK kinases (Canis familiaris)


name: ub-GLI is degraded by the proteasome (Sus scrofa)


name: SLC33A1 transports Ac-CoA from cytosol to Golgi lumen (Saccharomyces cerevisiae)


name: L-methionine salvage from methylthioadenosine


name: 1-hexadecanoyl-2-(5Z,8Z,11Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol => cholesteryl (5Z,8Z,11Z)-eicosatrienoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine


name: Kinetochore capture of astral microtubules (Sus scrofa)


name: pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)


name: glutathionylspermidine + ADP + phosphate + H(+) => spermidine + glutathione + ATP


name: ULK1 phosphorylates RIPK1 at S357 (Gallus gallus)


name: AKR1A1 oxidises BaPtDHD to BaP-7,8-dione (Mus musculus)


name: (-)-4'-methoxycyclopeptine + 2-oxoglutarate + O2 => (Z)-4'-methoxydehydrocyclopeptine + succinate + CO2 + H2O


name: STAT1 binds HEY1 gene promoter (Homo sapiens)


name: (2E)-geranyl diphosphate + H2O => sabinene hydrate + diphosphate


name: (3R)-hydroxyeicosanoyl-CoA + NAD(+) = 3-oxoeicosanoyl-CoA + NADH + H(+)


name: octanal + NADP(+) <=> (2E)-octenal + NADPH + H(+)


name: Dual mechanism MAP2K inhibitors bind MAP2Ks (Drosophila melanogaster)


name: Activated FGFR3 phosphorylates SHC1 (Xenopus tropicalis)


name: isochenodeoxycholate + NADP(+) => 3-oxochenodeoxycholate + NADPH + H(+)


name: LTA4H:Zn2+ hydrolyses 17R(16)-epoxy-DHA to AT-(N)PD1 (Canis familiaris)


name: 5-hydroxykynurenamine + CO2 => 5-hydroxy-L-kynurenine + H(+)


name: The geminin component of geminin:Cdt1 complexes is ubiquitinated, releasing Cdt1 (Canis familiaris)


name: 6-hydroxy-L-homoarginine + succinate + CO2 => L-homoarginine + 2-oxoglutarate + O2


name: RAB5 and GAPVD1 bind AP-2 (Canis familiaris)


name: B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda (Bos taurus)


name: nucleoside diphosphate phosphatase activity


name: LIG1 bound to POLB ligates SSB (Danio rerio)


name: (3S)-hydroxy-(6Z)-dodecenoyl-CoA + NAD(+) = 3-oxo-(6Z)-dodecenoyl-CoA + NADH + H(+)


name: protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity


name: Mg-protoporphyrin IX 13-monomethyl ester + S-adenosyl-L-methionine + H2O => Mg-13(1)-hydroxyprotoporphyrin 13-monomethyl ester + 5'-deoxyadenosine + L-methionine + H(+)


name: 7beta-hydroxy-3,12-dioxo-5beta-cholan-24-oate + NADP(+) => dehydrocholate + NADPH + H(+)


name: N(pros)-methyl-L-histidyl-[protein] + S-adenosyl-L-homocysteine + H(+) => L-histidyl-[protein] + S-adenosyl-L-methionine


name: ARL2:GTP:ARL2BP binds SLC25A4 (Sus scrofa)


name: CDKN1B is phosphorylated in response to estrogen (Mus musculus)


name: fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP (Gallus gallus)


name: DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Bos taurus)


name: N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlaNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,2) + H2O => N(4)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 7A1,2,3B2) + beta-D-mannose


name: 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA


name: anthraniloyl-CoA + 2 NADH + O2 + 2 H(+) <=> 2-amino-5-oxocyclohex-1-enecarbonyl-CoA + 2 NAD(+) + H2O


name: phosphatidylinositol-4,5-bisphosphate phospholipase C activity


name: Met-tRNAi binds to eIF2:GTP to form the ternary complex (Rattus norvegicus)


name: xylitol + NAD(+) => D-xylose + NADH + H(+)


name: YAP1 binds ZO-2 (TJP2) (Rattus norvegicus)


name: Activated IKK phosphorylates I-kappaB (Sus scrofa)


name: NOX2 generates superoxide anion from oxygen (Canis familiaris)


name: Dab2 is recruited to the junctional plaques (Sus scrofa)


name: FAD(in) + adenosine 3',5'-bisphosphate(out) = FAD(out) + adenosine 3',5'-bisphosphate(in)


name: PTPRJ dephosphorylates MET (Homo sapiens)


name: 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA => 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA


name: CARM1 methylates arginine-27 of histone H3 (H3R26) (Danio rerio)


name: Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Homo sapiens)


name: 2 [thyroglobulin]-3,5-diiodo-L-tyrosine + H2O2 => [thyroglobulin]-L-thyroxine + [thyroglobulin]-dehydroalanine + 2 H2O


name: 3-oxochol-4-en-22-oate + NADH + O2 + H(+) = 9alpha-hydroxy-3-oxochol-4-en-22-oate + NAD(+) + H2O


name: VxPx-containing ciliary membrane proteins are delivered to the ciliary membrane (Gallus gallus)


name: dehydroepiandrosterone 3-sulfate(in) => dehydroepiandrosterone 3-sulfate(out)


name: Ub-RibC-AXIN is degraded by the proteasome (Bos taurus)


name: a flavonol 3-O-beta-D-glucoside + H2O <=> a flavonol + D-glucose


name: isochorismate + L-glutamate + ATP <=> isochorismoyl-L-glutamate + AMP + diphosphate + H(+)


name: IL12 bound to IL12R internalises (Homo sapiens)


name: urate(in) + Na(+)(out) = urate(out) + Na(+)(in)


name: dGTP + glycolate + H(+) => N(2)-(1-hydroxy-2-oxoethyl)-dGTP + H2O


name: lanosterol + an acyl-CoA <=> lanosteryl ester + CoA


name: Processing of SCF isoform 1 (Homo sapiens)


name: TRIM27 polyubiquitinates PTEN (Homo sapiens)


name: 1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Plasmodium falciparum)


name: chloride + S-adenosyl-L-methionine = 5'-chloro-5'-deoxyadenosine + L-methionine


name: New CENPA-containing nucleosomes are deposited at the centromere (Xenopus tropicalis)


name: NEMF binds 60S ribosomal subunit:peptidyl-tRNA with nascent peptide (Homo sapiens)


name: Defective AMN does not transport GIF:Cbl (Homo sapiens)


name: SRF:MKL1 stimulate ITGB1 expression while SCAI inhibits it (Homo sapiens)


name: 4-amino-5-aminomethyl-2-methylpyrimidine + H2O => 4-amino-5-hydroxymethyl-2-methylpyrimidine + NH4(+)


name: CLCN4/5/6 exchange Cl- for H+ (Canis familiaris)


name: L-alanyl-L-histidine + H2O <=> L-histidine + L-alanine


name: RCC1 stimulates GDP to GTP exchange on RAN (Schizosaccharomyces pombe)


name: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA => 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA


name: RAC1 and CDC42 activate PAK2 (Mus musculus)


name: beta-D-galactose + D-glucose => lactose + H2O


name: MT-CO2 mRNA is translated (Homo sapiens)


name: RAB3GAP1:RAB3GAP2 recruits RAB18:GCDP to ER (Homo sapiens)


name: (2E,11Z)-octadecadienoyl-CoA + NADPH + H(+) = (11Z)-octadecenoyl-CoA + NADP(+)


name: 7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA => 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine


name: Gly-3-P+FAD->DHAP+FADH2 (catalyzed by mitochondrial Gly-Phos dehydrogenase) (Dictyostelium discoideum)


name: tricarballylate + FAD + H(+) <=> cis-aconitate + FADH2


name: Phosphorylation of L1 by CK-II (Caenorhabditis elegans)


name: MLKL binds PDCD6IP and SDCBP (Sus scrofa)


name: quinolin-8-ol + NADPH + O2 <=> 8-hydroxyquinoline N-oxide + NADP(+) + H2O


name: 4alpha-methyl-5alpha-cholest-8-en-3-one + CO2 + NADH => 4alpha-carboxy-4beta-methyl-5alpha-cholest-8-en-3beta-ol + NAD(+)


name: 4-hydroxylamino-2,6-dinitrotoluene + UDP-alpha-D-glucose <=> 4-hydroxylamino-2,6-dinitrotoluene-3C-beta-D-glucoside + UDP + H(+)


name: LYZ binds bacterial peptidoglycan (Xenopus tropicalis)


name: a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP


name: pseudouridine + ATP = psi-UMP + ADP + H(+)


name: (R)-piperazine-2-carboxamide + H2O <=> (R)-piperazine-2-carboxylate + NH4(+)


name: (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(15S)-hydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate


name: pre-replicative complex assembly involved in cell cycle DNA replication


name: DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)


name: riboflavin + alpha-D-glucose 1-phosphate => FMN + D-glucose


name: 3',4',7-trihydroxyisoflavone + S-adenosyl-L-methionine = 7,4'-dihydroxy-3'-methoxyisoflavone-7-olate + S-adenosyl-L-homocysteine + H(+)


name: Activated FGFR4 phosphorylates FRS3 (Gallus gallus)


name: BDNF gene expression is stimulated by NPAS4:ARNT2 (Homo sapiens)


name: 3-O-{alpha-L-Rha-(1->3)-[beta-D-Gal-(1->2)]-beta-D-GlcA}-quillaic acid beta-D-Xyl-(1->3)-beta-D-Xyl-(1->4)-alpha-L-Rha-(1->2)-beta-D-Fuc ester + UDP + H(+) => 3-O-{alpha-L-Rha-(1->3)-[beta-D-Gal-(1->2)]-beta-D-GlcA}-quillaic acid beta-D-Xyl-(1->4)-alpha-L-Rha-(1->2)-beta-D-Fuc ester + UDP-alpha-D-xylose


name: ethanol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1,2-diacyl-sn-glycero-3-phosphoethanol + choline


name: Phosphorylated ERBB2 heterodimers bind MEMO1 (Gallus gallus)


name: PITPNM1,2,3 exchange PI for PA (Schizosaccharomyces pombe)


name: KCNK dimers transport K+ from cytosol to extracellular region (Xenopus tropicalis)


name: 25-hydroxy 3-oxocholestane + AH2 => 3-oxocholestane + A + H2O


name: (R)-mevalonate + ATP = (R)-3-phosphomevalonate + ADP + H(+)


name: (3S)-hydroxy-(6Z,9Z)-dodecadienoyl-CoA + NAD(+) = 3-oxo-(6Z,9Z)-dodecadienoyl-CoA + NADH + H(+)


name: 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA => 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA


name: FDXR transfers electrons to FDX1,2 (FDX1L) (Bos taurus)


name: Deubiquitinated PTEN translocates to the cytosol (Homo sapiens)


name: ESR1:ESTG:P-TEFb recruited to paused RNA polymerase II on MYB gene (Bos taurus)


name: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate


name: MICAL1 produces NADP+, H2O2 (Xenopus tropicalis)


name: Superoxide reduces cytochrome c (Homo sapiens)


name: UDP(out) + ATP(in) <=> UDP(in) + ATP(out)


name: beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) (Canis familiaris)