positive regulation of cytoskeleton organization


HNRPQ_HUMAN Heterogeneous nuclear ribonucleoprotein Q (sprot)


negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

biolink:BiologicalProcess biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssenceOrOccurrent


positive regulation of cytoplasmic translation


CRD-mediated mRNA stability complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:ThingWithTaxon biolink:PhysicalEssence biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssenceOrOccurrent


histone pre-mRNA 3'end processing complex


TPST1_HUMAN Protein-tyrosine sulfotransferase 1 (sprot)


biolink:MolecularActivity biolink:Occurrent biolink:OntologyClass biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssenceOrOccurrent


PRP17_HUMAN Pre-mRNA-processing factor 17 (sprot)


B4GT3_HUMAN Beta-1,4-galactosyltransferase 3 (sprot)


B4GT4_HUMAN Beta-1,4-galactosyltransferase 4 (sprot)


4EBP3_HUMAN Eukaryotic translation initiation factor 4E-binding protein 3 (sprot)


negative regulation of translational initiation


RNBP6_HUMAN Ran-binding protein 6 (sprot)


CRBL2_HUMAN cAMP-responsive element-binding protein-like 2 (sprot)


positive regulation of lipid biosynthetic process


TDRD6_HUMAN Tudor domain-containing protein 6 (sprot)


NEMF_HUMAN Ribosome quality control complex subunit NEMF (sprot)


ribosome-associated ubiquitin-dependent protein catabolic process


glial cell-derived neurotrophic factor receptor binding


CIDEA_HUMAN Cell death activator CIDE-A (sprot)


negative regulation of cytokine production


negative regulation of lipid catabolic process


GMDS_HUMAN GDP-mannose 4,6 dehydratase (sprot)


'de novo' GDP-L-fucose biosynthetic process


FOXD2_HUMAN Forkhead box protein D2 (sprot)


NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (sprot)


regulation of rhodopsin mediated signaling pathway


cyclin-dependent protein serine/threonine kinase activator activity


regulation of cyclin-dependent protein serine/threonine kinase activity


phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter


phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter


cyclin/CDK positive transcription elongation factor complex


regulation of stress-activated MAPK cascade


signal transduction by p53 class mediator

biolink:Pathway biolink:OntologyClass biolink:BiologicalProcess biolink:Occurrent biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssenceOrOccurrent


vascular endothelial growth factor receptor 2 binding


positive regulation of receptor internalization


mesenchymal to epithelial transition involved in metanephros morphogenesis


negative regulation of bone mineralization


negative regulation of monocyte chemotaxis


positive regulation of branching involved in ureteric bud morphogenesis


negative regulation of osteoclast proliferation


positive regulation of peptidyl-tyrosine autophosphorylation


negative regulation of bone mineralization involved in bone maturation


positive regulation of signaling receptor activity


BUB1B_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (sprot)


metaphase/anaphase transition of mitotic cell cycle


protein localization to chromosome, centromeric region


PLOD3_HUMAN Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (sprot)


IF4E2_HUMAN Eukaryotic translation initiation factor 4E type 2 (sprot)


miRNA-mediated gene silencing by inhibition of translation


ISK4_HUMAN Serine protease inhibitor Kazal-type 4 (sprot)


detection of triacyl bacterial lipopeptide


detection of diacyl bacterial lipopeptide


cellular response to diacyl bacterial lipopeptide


cellular response to triacyl bacterial lipopeptide


positive regulation of interleukin-18 production


toll-like receptor TLR6:TLR2 signaling pathway


cellular response to bacterial lipopeptide


Toll-like receptor 1-Toll-like receptor 2 protein complex


Toll-like receptor 2-Toll-like receptor 6 protein complex


GFRA3_HUMAN GDNF family receptor alpha-3 (sprot)


DIAP1_HUMAN Protein diaphanous homolog 1 (sprot)


regulation of release of sequestered calcium ion into cytosol


'de novo' post-translational protein folding


AP180_HUMAN Clathrin coat assembly protein AP180 (sprot)


regulation of clathrin-dependent endocytosis


EXOC3_HUMAN Exocyst complex component 3 (sprot)


UD19_HUMAN UDP-glucuronosyltransferase 1A9 (sprot)


PDE8A_HUMAN High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (sprot)


KLH41_HUMAN Kelch-like protein 41 (sprot)


LMX1B_HUMAN LIM homeobox transcription factor 1-beta (sprot)


FAIM3_HUMAN Fas apoptotic inhibitory molecule 3 (sprot)


MOT2_HUMAN Monocarboxylate transporter 2 (sprot)


pyruvate secondary active transmembrane transporter activity


lactate transmembrane transporter activity


RAD1_HUMAN Cell cycle checkpoint protein RAD1 (sprot)


meiotic recombination checkpoint signaling


REV3L_HUMAN DNA polymerase zeta catalytic subunit (sprot)


JAK2_HUMAN Tyrosine-protein kinase JAK2 (sprot)


positive regulation of SMAD protein signal transduction


enzyme-linked receptor protein signaling pathway


mineralocorticoid receptor signaling pathway


positive regulation of phosphoprotein phosphatase activity


positive regulation of natural killer cell proliferation


programmed cell death induced by symbiont


granulocyte-macrophage colony-stimulating factor signaling pathway


positive regulation of tyrosine phosphorylation of STAT protein


regulation of nitric oxide biosynthetic process


negative regulation of heart contraction


regulation of receptor signaling pathway via JAK-STAT


positive regulation of receptor signaling pathway via JAK-STAT


positive regulation of NK T cell proliferation


type II interferon-mediated signaling pathway


growth hormone receptor signaling pathway via JAK-STAT


positive regulation of growth hormone receptor signaling pathway


positive regulation of leukocyte proliferation


activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway


positive regulation of growth factor dependent skeletal muscle satellite cell proliferation


positive regulation of epithelial cell apoptotic process


regulation of postsynapse to nucleus signaling pathway


positive regulation of T-helper 17 type immune response


granulocyte macrophage colony-stimulating factor receptor complex


MAFK_HUMAN Transcription factor MafK (sprot)


cysteine-type endopeptidase inhibitor activity


ANM3_HUMAN Protein arginine N-methyltransferase 3 (sprot)


protein-arginine omega-N monomethyltransferase activity


protein-arginine omega-N asymmetric methyltransferase activity


peptidyl-arginine methylation, to asymmetrical-dimethyl arginine


negative regulation of retinoic acid biosynthetic process


PEX10_HUMAN Peroxisome biogenesis factor 10 (sprot)


IMA7_HUMAN Importin subunit alpha-7 (sprot)


entry of viral genome into host nucleus through nuclear pore complex via importin


SRPX2_HUMAN Sushi repeat-containing protein SRPX2 (sprot)


YPEL1_HUMAN Protein yippee-like 1 (sprot)


UGDH_HUMAN UDP-glucose 6-dehydrogenase (sprot)


chondroitin sulfate biosynthetic process


TPST2_HUMAN Protein-tyrosine sulfotransferase 2 (sprot)


ABCC9_HUMAN ATP-binding cassette sub-family C member 9 (sprot)


ATP-activated inward rectifier potassium channel activity


ATPase-coupled cation transmembrane transporter activity


regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


potassium ion import across plasma membrane


potassium ion-transporting ATPase complex


negative regulation of B cell receptor signaling pathway


presynaptic active zone cytoplasmic component


NCKX1_HUMAN Sodium/potassium/calcium exchanger 1 (sprot)


calcium, potassium:sodium antiporter activity


calcium ion import across plasma membrane


ICMT_HUMAN Protein-S-isoprenylcysteine O-methyltransferase (sprot)


protein C-terminal carboxyl O-methyltransferase activity


protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity


CC14B_HUMAN Dual specificity protein phosphatase CDC14B (sprot)


MAGC1_HUMAN Melanoma-associated antigen C1 (sprot)


PLPL9_HUMAN 85/88 kDa calcium-independent phospholipase A2 (sprot)


calcium-independent phospholipase A2 activity


urinary bladder smooth muscle contraction


platelet activating factor metabolic process


negative regulation of synaptic transmission, glutamatergic


positive regulation of protein kinase C signaling


regulation of store-operated calcium channel activity


EIF1B_HUMAN Eukaryotic translation initiation factor 1b (sprot)


HCN1_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (sprot)


intracellular cAMP-activated cation channel activity


intracellular cAMP-activated cation channel activity involved in regulation of presynaptic membrane potential


general adaptation syndrome, behavioral process


regulation of postsynaptic membrane potential


regulation of SA node cell action potential


GALR3_HUMAN Galanin receptor type 3 (sprot)


G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger


CYTIP_HUMAN Cytohesin-interacting protein (sprot)


HPGDS_HUMAN Hematopoietic prostaglandin D synthase (sprot)


negative regulation of male germ cell proliferation


DPM1_HUMAN Dolichol-phosphate mannosyltransferase subunit 1 (sprot)


dolichol-linked oligosaccharide biosynthetic process


protein N-linked glycosylation via asparagine


USO1_HUMAN General vesicular transport factor p115 (sprot)


regulation of cellular response to insulin stimulus


Z354A_HUMAN Zinc finger protein 354A (sprot)


FMO6_HUMAN Putative dimethylaniline monooxygenase [N-oxide-forming] 6 (sprot)


S19A2_HUMAN Thiamine transporter 1 (sprot)


folic acid transmembrane transporter activity


thiamine-containing compound metabolic process


RT14_HUMAN 28S ribosomal protein S14, mitochondrial (sprot)


TOM1_HUMAN Target of Myb1 membrane trafficking protein (sprot)


polyubiquitin modification-dependent protein binding


TBX19_HUMAN T-box transcription factor TBX19 (sprot)


PRA10_HUMAN PRAME family member 10 (sprot)


PRAM4_HUMAN PRAME family member 4 (sprot)


PRAM2_HUMAN PRAME family member 2 (sprot)


HNRC1_HUMAN Heterogeneous nuclear ribonucleoprotein C-like 1 (sprot)


PRA11_HUMAN PRAME family member 11 (sprot)


H2B1K_HUMAN Histone H2B type 1-K (sprot)


F262_HUMAN 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (sprot)


positive regulation of glucokinase activity


CCD22_HUMAN Coiled-coil domain-containing protein 22 (sprot)


PQBP1_HUMAN Polyglutamine-binding protein 1 (sprot)


positive regulation of type I interferon production


PAGE4_HUMAN P antigen family member 4 (sprot)


TI17B_HUMAN Mitochondrial import inner membrane translocase subunit Tim17-B (sprot)


PRAF2_HUMAN PRA1 family protein 2 (sprot)


DKC1_HUMAN H/ACA ribonucleoprotein complex subunit DKC1 (sprot)


enzyme-directed rRNA pseudouridine synthesis


positive regulation of establishment of protein localization to telomere


positive regulation of protein localization to Cajal body


regulation of telomerase RNA localization to Cajal body


positive regulation of telomerase RNA localization to Cajal body


CAC1F_HUMAN Voltage-dependent L-type calcium channel subunit alpha-1F (sprot)


IF2P_HUMAN Eukaryotic translation initiation factor 5B (sprot)


ZG16_HUMAN Zymogen granule membrane protein 16 (sprot)


TRI13_HUMAN E3 ubiquitin-protein ligase TRIM13 (sprot)


negative regulation of viral transcription


GAS7_HUMAN Growth arrest-specific protein 7 (sprot)


EDF1_HUMAN Endothelial differentiation-related factor 1 (sprot)


TFIID-class transcription factor complex binding


KIN17_HUMAN DNA/RNA-binding protein KIN17 (sprot)


DIAP2_HUMAN Protein diaphanous homolog 2 (sprot)


SH21A_HUMAN SH2 domain-containing protein 1A (sprot)


natural killer cell mediated cytotoxicity


negative regulation of T cell receptor signaling pathway


MMP20_HUMAN Matrix metalloproteinase-20 (sprot)


G37L1_HUMAN G-protein coupled receptor 37-like 1 (sprot)


positive regulation of cerebellar granule cell precursor proliferation


negative regulation of astrocyte differentiation


DNJA2_HUMAN DnaJ homolog subfamily A member 2 (sprot)


BRD4_HUMAN Bromodomain-containing protein 4 (sprot)


RNA polymerase II CTD heptapeptide repeat kinase activity


RNA polymerase II C-terminal domain binding


regulation of Rho protein signal transduction


cell morphogenesis involved in neuron differentiation


maintenance of postsynaptic specialization structure


RAMP1_HUMAN Receptor activity-modifying protein 1 (sprot)


calcitonin gene-related peptide receptor activity


positive regulation of protein glycosylation


calcitonin gene-related peptide receptor signaling pathway


RAMP2_HUMAN Receptor activity-modifying protein 2 (sprot)


vascular associated smooth muscle cell development


adrenomedullin receptor signaling pathway


RAMP3_HUMAN Receptor activity-modifying protein 3 (sprot)


positive regulation of protein kinase A signaling


cross-receptor inhibition within G protein-coupled receptor heterodimer


G protein-coupled receptor signaling pathway involved in heart process


SHOX2_HUMAN Short stature homeobox protein 2 (sprot)


regulation of chondrocyte differentiation


positive regulation of skeletal muscle fiber development


cartilage development involved in endochondral bone morphogenesis


regulation of branching morphogenesis of a nerve


NSMA_HUMAN Sphingomyelin phosphodiesterase 2 (sprot)


TBL1X_HUMAN F-box-like/WD repeat-containing protein TBL1X (sprot)


B4GT2_HUMAN Beta-1,4-galactosyltransferase 2 (sprot)


antigen processing and presentation of exogenous peptide antigen via MHC class II


HUS1_HUMAN Checkpoint protein HUS1 (sprot)


PP1RB_HUMAN E3 ubiquitin-protein ligase PPP1R11 (sprot)


KCJ13_HUMAN Inward rectifier potassium channel 13 (sprot)


L-cystine transmembrane transporter activity


negative regulation of hydrogen peroxide biosynthetic process


positive regulation of mitochondrial membrane potential


regulation of melanin biosynthetic process


positive regulation of telomere maintenance


DNA strand resection involved in replication fork processing


release of sequestered calcium ion into cytosol by sarcoplasmic reticulum


negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway


inhibition of cysteine-type endopeptidase activity involved in apoptotic process


SCN2B_HUMAN Sodium channel subunit beta-2 (sprot)


voltage-gated sodium channel activity involved in cardiac muscle cell action potential


voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


membrane depolarization during cardiac muscle cell action potential


inorganic triphosphate phosphatase activity


FCG3B_HUMAN Low affinity immunoglobulin gamma Fc region receptor III-B (sprot)


LIRA1_HUMAN Leukocyte immunoglobulin-like receptor subfamily A member 1 (sprot)


LIRB3_HUMAN Leukocyte immunoglobulin-like receptor subfamily B member 3 (sprot)


LIRB5_HUMAN Leukocyte immunoglobulin-like receptor subfamily B member 5 (sprot)


ABCB7_HUMAN Iron-sulfur clusters transporter ABCB7, mitochondrial (sprot)


ABC-type iron-sulfur cluster transporter activity


positive regulation of heme biosynthetic process


iron-sulfur cluster export from the mitochondrion


positive regulation of iron-sulfur cluster assembly


MITF_HUMAN Microphthalmia-associated transcription factor (sprot)


regulation of osteoclast differentiation


positive regulation of DNA-templated transcription initiation


HSF2B_HUMAN Heat shock factor 2-binding protein (sprot)


double-strand break repair involved in meiotic recombination


KI21B_HUMAN Kinesin-like protein KIF21B (sprot)


PLCH2_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 (sprot)


SRGP2_HUMAN SLIT-ROBO Rho GTPase-activating protein 2 (sprot)


lamellipodium assembly involved in ameboidal cell migration


extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration


cerebellar granule cell precursor tangential migration


CAPON_HUMAN Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (sprot)


regulation of heart rate by chemical signal


positive regulation of nitric oxide mediated signal transduction


regulation of nitric-oxide synthase activity


regulation of ventricular cardiac muscle cell membrane repolarization


regulation of cardiac muscle cell action potential


postsynaptic actin cytoskeleton organization


regulation of high voltage-gated calcium channel activity


positive regulation of delayed rectifier potassium channel activity


regulation of calcium ion transmembrane transport via high voltage-gated calcium channel


positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization


positive regulation of peptidyl-cysteine S-nitrosylation


IGSF3_HUMAN Immunoglobulin superfamily member 3 (sprot)


AUXI_HUMAN Putative tyrosine-protein phosphatase auxilin (sprot)


extrinsic component of presynaptic endocytic zone membrane


XYLK_HUMAN Glycosaminoglycan xylosylkinase (sprot)


phosphotransferase activity, alcohol group as acceptor


DEN4B_HUMAN DENN domain-containing protein 4B (sprot)


regulation of Rab protein signal transduction


TMCC2_HUMAN Transmembrane and coiled-coil domains protein 2 (sprot)


amyloid precursor protein metabolic process


EFC14_HUMAN EF-hand calcium-binding domain-containing protein 14 (sprot)


FKTN_HUMAN Ribitol-5-phosphate transferase FKTN (sprot)


phosphotransferase activity, for other substituted phosphate groups


LRP3_HUMAN Low-density lipoprotein receptor-related protein 3 (sprot)


ADA23_HUMAN Disintegrin and metalloproteinase domain-containing protein 23 (sprot)


ADA11_HUMAN Disintegrin and metalloproteinase domain-containing protein 11 (sprot)


multicellular organismal response to stress


behavioral response to acetic acid induced pain


behavioral response to formalin induced pain


WDR1_HUMAN WD repeat-containing protein 1 (sprot)


regulation of actin filament depolymerization


establishment of planar polarity of follicular epithelium


non-canonical Wnt signaling pathway via JNK cascade


negative regulation of ectodermal cell fate specification


SLIT1_HUMAN Slit homolog 1 protein (sprot)


SLIT3_HUMAN Slit homolog 3 protein (sprot)


apoptotic process involved in luteolysis


MEGF6_HUMAN Multiple epidermal growth factor-like domains protein 6 (sprot)


LRP4_HUMAN Low-density lipoprotein receptor-related protein 4 (sprot)


synaptic assembly at neuromuscular junction


amyloid-beta clearance by cellular catabolic process


positive regulation of presynaptic membrane organization


positive regulation of skeletal muscle acetylcholine-gated channel clustering


AOC2_HUMAN Retina-specific copper amine oxidase (sprot)


tryptamine:oxygen oxidoreductase (deaminating) activity


phenethylamine:oxygen oxidoreductase (deaminating) activity


ATP9A_HUMAN Probable phospholipid-transporting ATPase IIA (sprot)


LDB3_HUMAN LIM domain-binding protein 3 (sprot)


N4BP1_HUMAN NEDD4-binding protein 1 (sprot)


ROCK2_HUMAN Rho-associated protein kinase 2 (sprot)


Rho-dependent protein serine/threonine kinase activity


positive regulation of cardiac muscle hypertrophy


positive regulation of centrosome duplication


positive regulation of connective tissue growth factor production


negative regulation of nitric oxide biosynthetic process


regulation of keratinocyte differentiation


negative regulation of biomineral tissue development


cellular response to testosterone stimulus


positive regulation of fibroblast growth factor production


regulation of angiotensin-activated signaling pathway


negative regulation of protein localization to lysosome


regulation of cellular response to hypoxia


positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process


positive regulation of protein localization to early endosome


positive regulation of amyloid precursor protein catabolic process


positive regulation of connective tissue replacement


MFA3L_HUMAN Microfibrillar-associated protein 3-like (sprot)


CLAP2_HUMAN CLIP-associating protein 2 (sprot)


microtubule organizing center organization


regulation of microtubule polymerization or depolymerization


positive regulation of extracellular matrix disassembly


negative regulation of wound healing, spreading of epidermal cells


positive regulation of basement membrane assembly involved in embryonic body morphogenesis


ZN623_HUMAN Zinc finger protein 623 (sprot)


PTCD1_HUMAN Pentatricopeptide repeat-containing protein 1, mitochondrial (sprot)


collateral sprouting in absence of injury


positive regulation of dendrite development


inositol 1,3,4,5 tetrakisphosphate binding


ZBED4_HUMAN Zinc finger BED domain-containing protein 4 (sprot)


DEPD5_HUMAN GATOR complex protein DEPDC5 (sprot)


cellular response to amino acid starvation


ATG13_HUMAN Autophagy-related protein 13 (sprot)


response to mitochondrial depolarisation


positive regulation of activated T cell proliferation


HIP1R_HUMAN Huntingtin-interacting protein 1-related protein (sprot)


negative regulation of actin filament polymerization


negative regulation of Arp2/3 complex-mediated actin nucleation


positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway


positive regulation of clathrin coat assembly


OBSL1_HUMAN Obscurin-like protein 1 (sprot)


BRE1B_HUMAN E3 ubiquitin-protein ligase BRE1B (sprot)


positive regulation of protein polyubiquitination


PHF2_HUMAN Lysine-specific demethylase PHF2 (sprot)


negative regulation of rDNA heterochromatin formation


ZC11A_HUMAN Zinc finger CCCH domain-containing protein 11A (sprot)


CLU_HUMAN Clustered mitochondria protein homolog (sprot)


RFIP3_HUMAN Rab11 family-interacting protein 3 (sprot)


negative regulation of adiponectin secretion


postsynaptic recycling endosome membrane


CAND2_HUMAN Cullin-associated NEDD8-dissociated protein 2 (sprot)


T22D2_HUMAN TSC22 domain family protein 2 (sprot)


SOCS5_HUMAN Suppressor of cytokine signaling 5 (sprot)


negative regulation of epidermal growth factor-activated receptor activity


negative regulation of T-helper 2 cell differentiation


negative regulation of monocyte chemotactic protein-1 production


vascular endothelial cell response to fluid shear stress


photoreceptor cell outer segment organization


KDM4A_HUMAN Lysine-specific demethylase 4A (sprot)


histone H3K36me2/H3K36me3 demethylase activity


DJC13_HUMAN DnaJ homolog subfamily C member 13 (sprot)


regulation of early endosome to recycling endosome transport


regulation of early endosome to late endosome transport


PHAR2_HUMAN Phosphatase and actin regulator 2 (sprot)


PP6R2_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 2 (sprot)


ATS4_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 4 (sprot)


CNOT3_HUMAN CCR4-NOT transcription complex subunit 3 (sprot)


CREST_HUMAN Calcium-responsive transactivator (sprot)


ANR17_HUMAN Ankyrin repeat domain-containing protein 17 (sprot)


positive regulation of MDA-5 signaling pathway


positive regulation of RIG-I signaling pathway


SIN3B_HUMAN Paired amphipathic helix protein Sin3b (sprot)


AT2C2_HUMAN Calcium-transporting ATPase type 2C member 2 (sprot)


DNJB6_HUMAN DnaJ homolog subfamily B member 6 (sprot)


syncytiotrophoblast cell differentiation involved in labyrinthine layer development


negative regulation of inclusion body assembly


glucuronate catabolic process to xylulose 5-phosphate


PX11A_HUMAN Peroxisomal membrane protein 11A (sprot)


LRP5_HUMAN Low-density lipoprotein receptor-related protein 5 (sprot)


coreceptor activity involved in Wnt signaling pathway


coreceptor activity involved in canonical Wnt signaling pathway


cell-cell signaling involved in mammary gland development


negative regulation of protein serine/threonine kinase activity


apoptotic process involved in blood vessel morphogenesis


NPIB7_HUMAN Nuclear pore complex-interacting protein family member B7 (sprot)


TM127_HUMAN Transmembrane protein 127 (sprot)


COQ9_HUMAN Ubiquinone biosynthesis protein COQ9, mitochondrial (sprot)


NDUS7_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (sprot)


oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor


SIM24_HUMAN Small integral membrane protein 24 (sprot)


Z780A_HUMAN Zinc finger protein 780A (sprot)


GA45B_HUMAN Growth arrest and DNA damage-inducible protein GADD45 beta (sprot)


intracellular protein transmembrane transport


NDUS2_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (sprot)


mitochondrial ATP synthesis coupled electron transport


calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules


UDB11_HUMAN UDP-glucuronosyltransferase 2B11 (sprot)


GLRA3_HUMAN Glycine receptor subunit alpha-3 (sprot)


extracellularly glycine-gated chloride channel activity


glycine-gated chloride ion channel activity


ZPR1_HUMAN Zinc finger protein ZPR1 (sprot)


positive regulation of transcription involved in G1/S transition of mitotic cell cycle


negative regulation of motor neuron apoptotic process


UBP12_HUMAN Ubiquitin carboxyl-terminal hydrolase 12 (sprot)


DUS11_HUMAN RNA/RNP complex-1-interacting phosphatase (sprot)


NIPS2_HUMAN Protein NipSnap homolog 2 (sprot)


positive regulation of high voltage-gated calcium channel activity


LRRN2_HUMAN Leucine-rich repeat neuronal protein 2 (sprot)


HMMR_HUMAN Hyaluronan mediated motility receptor (sprot)


TBX10_HUMAN T-box transcription factor TBX10 (sprot)


regulation of dendritic spine development


dense core granule cytoskeletal transport


CILP1_HUMAN Cartilage intermediate layer protein 1 (sprot)


negative regulation of insulin-like growth factor receptor signaling pathway


negative regulation of SMAD protein signal transduction


PDCD6_HUMAN Programmed cell death protein 6 (sprot)


vascular endothelial growth factor receptor-2 signaling pathway


positive regulation of protein monoubiquitination


LX12B_HUMAN Arachidonate 12-lipoxygenase, 12R-type (sprot)


oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen


GCYB2_HUMAN Guanylate cyclase soluble subunit beta-2 (sprot)


FKBP6_HUMAN Inactive peptidyl-prolyl cis-trans isomerase FKBP6 (sprot)


DNA methylation involved in gamete generation


ZN253_HUMAN Zinc finger protein 253 (sprot)


TBCA_HUMAN Tubulin-specific chaperone A (sprot)


VATG1_HUMAN V-type proton ATPase subunit G 1 (sprot)


cellular response to increased oxygen levels


vacuolar proton-transporting V-type ATPase, V1 domain


VPS4B_HUMAN Vacuolar protein sorting-associated protein 4B (sprot)


endosome to lysosome transport via multivesicular body sorting pathway


late endosome to lysosome transport via multivesicular body sorting pathway


ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway


positive regulation of centriole elongation


MPU1_HUMAN Mannose-P-dolichol utilization defect 1 protein (sprot)


ENTP6_HUMAN Ectonucleoside triphosphate diphosphohydrolase 6 (sprot)


nucleoside diphosphate phosphatase activity


ENTP3_HUMAN Ectonucleoside triphosphate diphosphohydrolase 3 (sprot)


ENTP5_HUMAN Nucleoside diphosphate phosphatase ENTPD5 (sprot)


PROP1_HUMAN Homeobox protein prophet of Pit-1 (sprot)


somatotropin secreting cell differentiation


ZN217_HUMAN Zinc finger protein 217 (sprot)


BCAS1_HUMAN Breast carcinoma-amplified sequence 1 (sprot)


PITX3_HUMAN Pituitary homeobox 3 (sprot)


response to methamphetamine hydrochloride


positive regulation of cell proliferation in midbrain


cellular response to glial cell derived neurotrophic factor


TP4A3_HUMAN Protein tyrosine phosphatase type IVA 3 (sprot)


prenylated protein tyrosine phosphatase activity


positive regulation of establishment of protein localization


regulation of diacylglycerol biosynthetic process


H2AY_HUMAN Core histone macro-H2A.1 (sprot)


positive regulation of maintenance of mitotic sister chromatid cohesion


epigenetic regulation of gene expression


establishment of protein localization to chromatin


negative regulation of transcription of nucleolar large rRNA by RNA polymerase I


negative regulation of cell cycle G2/M phase transition


regulation of response to oxidative stress


positive regulation of endodermal cell differentiation


negative regulation of protein localization to chromosome, telomeric region


positive regulation of cytoplasmic translational initiation


ZN737_HUMAN Zinc finger protein 737 (sprot)


NCOR1_HUMAN Nuclear receptor corepressor 1 (sprot)


negative regulation of fatty acid metabolic process


VAMP4_HUMAN Vesicle-associated membrane protein 4 (sprot)


NDUS6_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (sprot)


PEX14_HUMAN Peroxisomal membrane protein PEX14 (sprot)


protein import into peroxisome matrix, docking


protein import into peroxisome matrix, translocation


protein import into peroxisome matrix, substrate release


TRIM3_HUMAN Tripartite motif-containing protein 3 (sprot)


ULK1_HUMAN Serine/threonine-protein kinase ULK1 (sprot)


positive regulation of autophagosome assembly


extrinsic component of omegasome membrane


extrinsic component of phagophore assembly site membrane


TULP3_HUMAN Tubby-related protein 3 (sprot)


intraciliary transport particle A binding


negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning


smoothened signaling pathway involved in dorsal/ventral neural tube patterning


negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning


LAT3_HUMAN Large neutral amino acids transporter small subunit 3 (sprot)


negative regulation of amino acid transport


L-valine transmembrane transporter activity


amino acid transmembrane transporter activity


neutral L-amino acid transmembrane transporter activity


L-isoleucine transmembrane transporter activity


L-leucine transmembrane transporter activity


GPR32_HUMAN Probable G-protein coupled receptor 32 (sprot)


CISY_HUMAN Citrate synthase, mitochondrial (sprot)


SPAG7_HUMAN Sperm-associated antigen 7 (sprot)


RM33_HUMAN 39S ribosomal protein L33, mitochondrial (sprot)


SC22B_HUMAN Vesicle-trafficking protein SEC22b (sprot)


DEAF1_HUMAN Deformed epidermal autoregulatory factor 1 homolog (sprot)


regulation of mammary gland epithelial cell proliferation


PR40A_HUMAN Pre-mRNA-processing factor 40 homolog A (sprot)


HYPM_HUMAN Huntingtin-interacting protein M (sprot)


TACC1_HUMAN Transforming acidic coiled-coil-containing protein 1 (sprot)


peroxisome proliferator activated receptor binding


nuclear thyroid hormone receptor binding


NDK6_HUMAN Nucleoside diphosphate kinase 6 (sprot)


DPOLQ_HUMAN DNA polymerase theta (sprot)


double-strand break repair via alternative nonhomologous end joining


CDC45_HUMAN Cell division control protein 45 homolog (sprot)


DNA unwinding involved in DNA replication


GGYF1_HUMAN GRB10-interacting GYF protein 1 (sprot)


MSPD3_HUMAN Motile sperm domain-containing protein 3 (sprot)


FBX24_HUMAN F-box only protein 24 (sprot)


LRCH4_HUMAN Leucine-rich repeat and calponin homology domain-containing protein 4 (sprot)


protein insertion into mitochondrial outer membrane


VP26A_HUMAN Vacuolar protein sorting-associated protein 26A (sprot)


ZN254_HUMAN Zinc finger protein 254 (sprot)


NDUB1_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (sprot)


MPPB_HUMAN Mitochondrial-processing peptidase subunit beta (sprot)


protein processing involved in protein targeting to mitochondrion


mitochondrial calcium ion transmembrane transport


mitochondrial processing peptidase complex


MAF_HUMAN Transcription factor Maf (sprot)


SAP30_HUMAN Histone deacetylase complex subunit SAP30 (sprot)


modulation by host of symbiont transcription


MED24_HUMAN Mediator of RNA polymerase II transcription subunit 24 (sprot)


KTNA1_HUMAN Katanin p60 ATPase-containing subunit A1 (sprot)


RDH16_HUMAN Retinol dehydrogenase 16 (sprot)


PAGE1_HUMAN P antigen family member 1 (sprot)


ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 (sprot)


mRNA splicing, via endonucleolytic cleavage and ligation


mRNA cleavage involved in mRNA processing


positive regulation of endoplasmic reticulum unfolded protein response


E2F6_HUMAN Transcription factor E2F6 (sprot)


CRLF1_HUMAN Cytokine receptor-like factor 1 (sprot)


ciliary neurotrophic factor receptor binding


Z324A_HUMAN Zinc finger protein 324A (sprot)


NR1I2_HUMAN Nuclear receptor subfamily 1 group I member 2 (sprot)


LGR5_HUMAN Leucine-rich repeat-containing G-protein coupled receptor 5 (sprot)


FRAT2_HUMAN GSK-3-binding protein FRAT2 (sprot)


beta-catenin destruction complex disassembly


PSIP1_HUMAN PC4 and SFRS1-interacting protein (sprot)


negative regulation of cholesterol biosynthetic process


TAD2A_HUMAN Transcriptional adapter 2-alpha (sprot)


SUPT3_HUMAN Transcription initiation protein SPT3 homolog (sprot)


coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway


NDUS3_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (sprot)


CAH11_HUMAN Carbonic anhydrase-related protein 11 (sprot)


SRS10_HUMAN Serine/arginine-rich splicing factor 10 (sprot)


regulation of mRNA splicing, via spliceosome


DNA replication preinitiation complex assembly


negative regulation of DNA-templated DNA replication


CLN5_HUMAN Ceroid-lipofuscinosis neuronal protein 5 (sprot)


HSBP1_HUMAN Heat shock factor-binding protein 1 (sprot)


TNR21_HUMAN Tumor necrosis factor receptor superfamily member 21 (sprot)


negative regulation of interleukin-5 production


negative regulation of T cell proliferation


ECI2_HUMAN Enoyl-CoA delta isomerase 2 (sprot)


KHDR3_HUMAN KH domain-containing, RNA-binding, signal transduction-associated protein 3 (sprot)


TADA3_HUMAN Transcriptional adapter 3 (sprot)


TAF5L_HUMAN TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (sprot)


regulation of somatic stem cell population maintenance


BAF_HUMAN Barrier-to-autointegration factor (sprot)


negative regulation of protein ADP-ribosylation


SF3B1_HUMAN Splicing factor 3B subunit 1 (sprot)


CSDE1_HUMAN Cold shock domain-containing protein E1 (sprot)


nuclear-transcribed mRNA catabolic process, no-go decay


ZN821_HUMAN Zinc finger protein 821 (sprot)


cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration


radial glia guided migration of Purkinje cell


radial glia-guided pyramidal neuron migration


WBP4_HUMAN WW domain-binding protein 4 (sprot)


SKAP2_HUMAN Src kinase-associated phosphoprotein 2 (sprot)


JERKY_HUMAN Jerky protein homolog (sprot)


PRKRA_HUMAN Interferon-inducible double-stranded RNA-dependent protein kinase activator A (sprot)


RF1M_HUMAN Peptide chain release factor 1, mitochondrial (sprot)


RPC9_HUMAN DNA-directed RNA polymerase III subunit RPC9 (sprot)


collagen binding involved in cell-matrix adhesion


LRP6_HUMAN Low-density lipoprotein receptor-related protein 6 (sprot)


low-density lipoprotein particle receptor activity


negative regulation of smooth muscle cell apoptotic process


canonical Wnt signaling pathway involved in neural crest cell differentiation


Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation


KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 (sprot)


positive regulation of CREB transcription factor activity


MED6_HUMAN Mediator of RNA polymerase II transcription subunit 6 (sprot)


MYCB2_HUMAN E3 ubiquitin-protein ligase MYCBP2 (sprot)


FOXH1_HUMAN Forkhead box protein H1 (sprot)


ventricular trabecula myocardium morphogenesis


embryonic heart tube anterior/posterior pattern specification


nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry


PGRP1_HUMAN Peptidoglycan recognition protein 1 (sprot)


negative regulation of natural killer cell differentiation involved in immune response


biological process involved in interaction with host


CLC3A_HUMAN C-type lectin domain family 3 member A (sprot)


KBL_HUMAN 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (sprot)


SPAG6_HUMAN Sperm-associated antigen 6 (sprot)


GCM2_HUMAN Chorion-specific transcription factor GCMb (sprot)


UBP2_HUMAN Ubiquitin carboxyl-terminal hydrolase 2 (sprot)


LYPA1_HUMAN Acyl-protein thioesterase 1 (sprot)


negative regulation of Golgi to plasma membrane protein transport


LFTY1_HUMAN Left-right determination factor 1 (sprot)


ERAL1_HUMAN GTPase Era, mitochondrial (sprot)


DEDD_HUMAN Death effector domain-containing protein (sprot)


PRDM1_HUMAN PR domain zinc finger protein 1 (sprot)


regulation of natural killer cell differentiation


regulation of extrathymic T cell differentiation


REM1_HUMAN GTP-binding protein REM 1 (sprot)


negative regulation of high voltage-gated calcium channel activity


positive regulation of transforming growth factor beta1 production


positive regulation of collagen biosynthetic process


positive regulation of platelet-derived growth factor production


negative regulation of RNA biosynthetic process


CTAG2_HUMAN Cancer/testis antigen 2 (sprot)


U520_HUMAN U5 small nuclear ribonucleoprotein 200 kDa helicase (sprot)


cis assembly of pre-catalytic spliceosome


spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)


MTU1_HUMAN Mitochondrial tRNA-specific 2-thiouridylase 1 (sprot)


negative regulation of phosphoprotein phosphatase activity


OFD1_HUMAN Centriole and centriolar satellite protein OFD1 (sprot)


KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 (sprot)


RFPL1_HUMAN Ret finger protein-like 1 (sprot)


positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis


RFPL2_HUMAN Ret finger protein-like 2 (sprot)


RFPL3_HUMAN Ret finger protein-like 3 (sprot)


SURF6_HUMAN Surfeit locus protein 6 (sprot)


PPM1B_HUMAN Protein phosphatase 1B (sprot)


negative regulation of interferon-beta production


ADAP1_HUMAN Arf-GAP with dual PH domain-containing protein 1 (sprot)


KRA58_HUMAN Keratin-associated protein 5-8 (sprot)


structural constituent of skin epidermis


UTP20_HUMAN Small subunit processome component 20 homolog (sprot)


endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


NU155_HUMAN Nuclear pore complex protein Nup155 (sprot)


atrial cardiac muscle cell action potential


SCRG1_HUMAN Scrapie-responsive protein 1 (sprot)


CXB3_HUMAN Gap junction beta-3 protein (sprot)


GPX5_HUMAN Epididymal secretory glutathione peroxidase (sprot)


STK16_HUMAN Serine/threonine-protein kinase 16 (sprot)


WDHD1_HUMAN WD repeat and HMG-box DNA-binding protein 1 (sprot)


CRTAP_HUMAN Cartilage-associated protein (sprot)


negative regulation of post-translational protein modification


S2512_HUMAN Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (sprot)


3-sulfino-L-alanine: proton, glutamate antiporter activity


aspartate:glutamate, proton antiporter activity


acidic amino acid transmembrane transporter activity


aspartate family amino acid metabolic process


positive regulation of glucose metabolic process


negative regulation of glucose catabolic process to lactate via pyruvate


positive regulation of ATP biosynthetic process


P3C2G_HUMAN Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (sprot)


phosphatidylinositol phosphate kinase activity


S22A3_HUMAN Solute carrier family 22 member 3 (sprot)


B3GL1_HUMAN UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 (sprot)


TRPA1_HUMAN Transient receptor potential cation channel subfamily A member 1 (sprot)


temperature-gated cation channel activity


detection of mechanical stimulus involved in sensory perception of pain


detection of chemical stimulus involved in sensory perception of pain


TCEA3_HUMAN Transcription elongation factor A protein 3 (sprot)


RA51D_HUMAN DNA repair protein RAD51 homolog 4 (sprot)


negative regulation of dopamine receptor signaling pathway


cellular response to electrical stimulus


RHBL1_HUMAN Rhomboid-related protein 1 (sprot)


proton-transporting V-type ATPase complex


vacuolar proton-transporting V-type ATPase, V0 domain


vacuolar proton-transporting V-type ATPase complex


GRAP2_HUMAN GRB2-related adapter protein 2 (sprot)


RNH2A_HUMAN Ribonuclease H2 subunit A (sprot)


CD123_HUMAN Cell division cycle protein 123 homolog (sprot)


eukaryotic translation initiation factor 2 complex assembly


UDB17_HUMAN UDP-glucuronosyltransferase 2B17 (sprot)


ZMY10_HUMAN Zinc finger MYND domain-containing protein 10 (sprot)


positive regulation of motile cilium assembly


PR15A_HUMAN Protein phosphatase 1 regulatory subunit 15A (sprot)


positive regulation of translational initiation in response to stress


negative regulation of protein dephosphorylation


regulation of translational initiation by eIF2 alpha dephosphorylation


protein localization to endoplasmic reticulum


positive regulation of peptidyl-serine dephosphorylation


negative regulation of PERK-mediated unfolded protein response


positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation


BCAR3_HUMAN Breast cancer anti-estrogen resistance protein 3 (sprot)


POP7_HUMAN Ribonuclease P protein subunit p20 (sprot)


RPP40_HUMAN Ribonuclease P protein subunit p40 (sprot)


ZN189_HUMAN Zinc finger protein 189 (sprot)


EIF3G_HUMAN Eukaryotic translation initiation factor 3 subunit G (sprot)


EIF3J_HUMAN Eukaryotic translation initiation factor 3 subunit J (sprot)


CBR3_HUMAN Carbonyl reductase [NADPH] 3 (sprot)


CNMD_HUMAN Leukocyte cell-derived chemotaxin 1 (sprot)


PSD10_HUMAN 26S proteasome non-ATPase regulatory subunit 10 (sprot)


CIB2_HUMAN Calcium and integrin-binding family member 2 (sprot)


KLF7_HUMAN Krueppel-like factor 7 (sprot)


regulation of epidermal cell differentiation


negative regulation of insulin secretion involved in cellular response to glucose stimulus


negative regulation of adipose tissue development


AP1G2_HUMAN AP-1 complex subunit gamma-like 2 (sprot)


FACE1_HUMAN CAAX prenyl protease 1 homolog (sprot)


ventricular cardiac muscle tissue development


regulation of DNA damage response, signal transduction by p53 class mediator


regulation of stress-activated protein kinase signaling cascade


response to DNA damage checkpoint signaling


regulation of mitotic cell cycle DNA replication


regulation of histone H4-K16 acetylation


regulation of termination of RNA polymerase I transcription


cholesterol biosynthetic process via desmosterol


cholesterol biosynthetic process via lathosterol


PPR37_HUMAN Protein phosphatase 1 regulatory subunit 37 (sprot)


TPC6A_HUMAN Trafficking protein particle complex subunit 6A (sprot)


CEAM4_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 4 (sprot)


IDHC_HUMAN Isocitrate dehydrogenase [NADP] cytoplasmic (sprot)


isocitrate dehydrogenase (NADP+) activity


regulation of phospholipid catabolic process


regulation of phospholipid biosynthetic process


GATB_HUMAN Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial (sprot)


SCO1_HUMAN Protein SCO1 homolog, mitochondrial (sprot)


RBBP9_HUMAN Serine hydrolase RBBP9 (sprot)


STAM2_HUMAN Signal transducing adapter molecule 2 (sprot)


TNF13_HUMAN Tumor necrosis factor ligand superfamily member 13 (sprot)


positive regulation of isotype switching to IgA isotypes


AL1L1_HUMAN Cytosolic 10-formyltetrahydrofolate dehydrogenase (sprot)


hydroxymethyl-, formyl- and related transferase activity


TUSC2_HUMAN Tumor suppressor candidate 2 (sprot)


neutrophil-mediated killing of gram-negative bacterium


ST1C4_HUMAN Sulfotransferase 1C4 (sprot)


GABR2_HUMAN Gamma-aminobutyric acid type B receptor subunit 2 (sprot)


G protein-coupled GABA receptor activity


G protein-coupled receptor heterodimeric complex


MMP23_HUMAN Matrix metalloproteinase-23 (sprot)


RASF9_HUMAN Ras association domain-containing protein 9 (sprot)


trans-Golgi network transport vesicle membrane


DGAT1_HUMAN Diacylglycerol O-acyltransferase 1 (sprot)


very-low-density lipoprotein particle assembly


long-chain fatty-acyl-CoA metabolic process


SOAT2_HUMAN Sterol O-acyltransferase 2 (sprot)


macrophage derived foam cell differentiation


low-density lipoprotein particle clearance


cyclin-dependent protein serine/threonine kinase activity


phosphorylation of RNA polymerase II C-terminal domain


positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues


DHRS3_HUMAN Short-chain dehydrogenase/reductase 3 (sprot)


DGKI_HUMAN Diacylglycerol kinase iota (sprot)


PAK3_HUMAN Serine/threonine-protein kinase PAK 3 (sprot)


positive regulation of fibroblast migration


cellular response to organic cyclic compound


positive regulation of DNA biosynthetic process


PRAF3_HUMAN PRA1 family protein 3 (sprot)


negative regulation of L-glutamate import across plasma membrane


negative regulation of mitochondrial membrane potential


neuron death in response to oxidative stress


L-glutamate import across plasma membrane


RGS9_HUMAN Regulator of G-protein signaling 9 (sprot)


SERF1_HUMAN Small EDRK-rich factor 1 (sprot)


monocyte activation involved in immune response


macrophage activation involved in immune response


PIAS1_HUMAN E3 SUMO-protein ligase PIAS1 (sprot)


positive regulation of protein sumoylation


PIAS2_HUMAN E3 SUMO-protein ligase PIAS2 (sprot)


SPF27_HUMAN Pre-mRNA-splicing factor SPF27 (sprot)


BODG_HUMAN Gamma-butyrobetaine dioxygenase (sprot)


DNJC8_HUMAN DnaJ homolog subfamily C member 8 (sprot)


SPF30_HUMAN Survival of motor neuron-related-splicing factor 30 (sprot)


RAD17_HUMAN Cell cycle checkpoint protein RAD17 (sprot)


mitotic intra-S DNA damage checkpoint signaling


ATP5H_HUMAN ATP synthase subunit d, mitochondrial (sprot)


proton-transporting ATP synthase activity, rotational mechanism


proton motive force-driven ATP synthesis


mitochondrial proton-transporting ATP synthase complex


LYZL6_HUMAN Lysozyme-like protein 6 (sprot)


CABYR_HUMAN Calcium-binding tyrosine phosphorylation-regulated protein (sprot)


epithelial cilium movement involved in extracellular fluid movement


DNJB5_HUMAN DnaJ homolog subfamily B member 5 (sprot)


regulation of toll-like receptor 4 signaling pathway


positive regulation of synaptic transmission, dopaminergic


positive regulation of heterotypic cell-cell adhesion


positive regulation of toll-like receptor 3 signaling pathway


positive regulation of skeletal muscle tissue development


positive regulation of cell-cell adhesion mediated by cadherin


CDKA2_HUMAN Cyclin-dependent kinase 2-associated protein 2 (sprot)


regulation of microtubule cytoskeleton organization


TRIO_HUMAN Triple functional domain protein (sprot)


transmembrane receptor protein tyrosine phosphatase signaling pathway


postsynaptic modulation of chemical synaptic transmission


ATP5L_HUMAN ATP synthase subunit g, mitochondrial (sprot)


AKAP3_HUMAN A-kinase anchor protein 3 (sprot)


MPDZ_HUMAN Multiple PDZ domain protein (sprot)


SNPC5_HUMAN snRNA-activating protein complex subunit 5 (sprot)


RNA polymerase III general transcription initiation factor activity


transcription initiation at RNA polymerase III promoter


snRNA transcription by RNA polymerase III


SASH3_HUMAN SAM and SH3 domain-containing protein 3 (sprot)


CD4-positive, alpha-beta T cell differentiation


homeostasis of number of cells within a tissue


OR2B3_HUMAN Putative olfactory receptor 2B3 (sprot)


OR2J3_HUMAN Olfactory receptor 2J3 (sprot)


OR2J2_HUMAN Olfactory receptor 2J2 (sprot)


regulation of the force of heart contraction


negative regulation of cardiac muscle hypertrophy


protein maturation by iron-sulfur cluster transfer


KT33A_HUMAN Keratin, type I cuticular Ha3-I (sprot)


KRT34_HUMAN Keratin, type I cuticular Ha4 (sprot)


KRT36_HUMAN Keratin, type I cuticular Ha6 (sprot)


KRT37_HUMAN Keratin, type I cuticular Ha7 (sprot)


KRT38_HUMAN Keratin, type I cuticular Ha8 (sprot)


RL1D1_HUMAN Ribosomal L1 domain-containing protein 1 (sprot)


negative regulation of programmed cell death


negative regulation of response to endoplasmic reticulum stress


negative regulation of ATF6-mediated unfolded protein response


negative regulation of type B pancreatic cell apoptotic process


CLPX_HUMAN ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (sprot)


proteolysis involved in protein catabolic process


NCTR1_HUMAN Natural cytotoxicity triggering receptor 1 (sprot)


regulation of natural killer cell mediated cytotoxicity


CDKL5_HUMAN Cyclin-dependent kinase-like 5 (sprot)


ERIT1_HUMAN Putative uncharacterized protein encoded by ERC2-IT1 (sprot)


NEUL1_HUMAN E3 ubiquitin-protein ligase NEURL1 (sprot)


translation factor activity, non-nucleic acid binding


positive regulation of long-term neuronal synaptic plasticity


positive regulation of synapse maturation


S14L2_HUMAN SEC14-like protein 2 (sprot)


regulation of store-operated calcium entry


ERG24_HUMAN Delta(14)-sterol reductase TM7SF2 (sprot)


RNF8_HUMAN E3 ubiquitin-protein ligase RNF8 (sprot)


regulation of neurotransmitter secretion


CIAO1_HUMAN Probable cytosolic iron-sulfur protein assembly protein CIAO1 (sprot)


PDE5A_HUMAN cGMP-specific 3',5'-cyclic phosphodiesterase (sprot)


regulation of nitric oxide mediated signal transduction


negative regulation of cardiac muscle contraction


positive regulation of oocyte development


DFFB_HUMAN DNA fragmentation factor subunit beta (sprot)


ZFAN5_HUMAN AN1-type zinc finger protein 5 (sprot)


RGS20_HUMAN Regulator of G-protein signaling 20 (sprot)


S22A5_HUMAN Solute carrier family 22 member 5 (sprot)


carnitine transmembrane transporter activity


positive regulation of intestinal epithelial structure maintenance


sodium-dependent organic cation transport


PDE9A_HUMAN High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (sprot)


bicarbonate transmembrane transporter activity


FGF18_HUMAN Fibroblast growth factor 18 (sprot)


SRP72_HUMAN Signal recognition particle subunit SRP72 (sprot)


signal recognition particle, endoplasmic reticulum targeting


OR7C1_HUMAN Olfactory receptor 7C1 (sprot)


OR7AA_HUMAN Olfactory receptor 7A10 (sprot)


DXO_HUMAN Decapping and exoribonuclease protein (sprot)


RNA NAD-cap (NAD-forming) hydrolase activity


TRPM2_HUMAN Transient receptor potential cation channel subfamily M member 2 (sprot)


manganese ion transmembrane transporter activity


calcium-mediated signaling using intracellular calcium source


cellular response to purine-containing compound


cellular response to temperature stimulus


DDAH1_HUMAN N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (sprot)


regulation of systemic arterial blood pressure


nitric oxide mediated signal transduction


negative regulation of cellular response to hypoxia


RECQ4_HUMAN ATP-dependent DNA helicase Q4 (sprot)


RECQ5_HUMAN ATP-dependent DNA helicase Q5 (sprot)


replication-born double-strand break repair via sister chromatid exchange


RMP_HUMAN Unconventional prefoldin RPB5 interactor 1 (sprot)


negative regulation of phosphatase activity


B3GA3_HUMAN Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 (sprot)


chondroitin sulfate proteoglycan biosynthetic process


dermatan sulfate proteoglycan biosynthetic process


ST17B_HUMAN Serine/threonine-protein kinase 17B (sprot)


ECM2_HUMAN Extracellular matrix protein 2 (sprot)


LY6H_HUMAN Lymphocyte antigen 6H (sprot)


negative regulation of signaling receptor activity


MTA2_HUMAN Metastasis-associated protein MTA2 (sprot)


DPM2_HUMAN Dolichol phosphate-mannose biosynthesis regulatory protein (sprot)


ammonium transmembrane transporter activity


hydrogen peroxide transmembrane transport


UBP1_HUMAN Ubiquitin carboxyl-terminal hydrolase 1 (sprot)


positive regulation of error-prone translesion synthesis


AL1A2_HUMAN Retinal dehydrogenase 2 (sprot)


3-chloroallyl aldehyde dehydrogenase activity


9-cis-retinoic acid biosynthetic process


retinoic acid receptor signaling pathway involved in somitogenesis


regulation of vascular endothelial cell proliferation


STK10_HUMAN Serine/threonine-protein kinase 10 (sprot)


ACL6B_HUMAN Actin-like protein 6B (sprot)


KPCD3_HUMAN Serine/threonine-protein kinase D3 (sprot)


calcium-dependent protein kinase C activity


GFPT2_HUMAN Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (sprot)


glutamine-fructose-6-phosphate transaminase (isomerizing) activity


RGS11_HUMAN Regulator of G-protein signaling 11 (sprot)


TPPP_HUMAN Tubulin polymerization-promoting protein (sprot)


positive regulation of protein polymerization


microtubule nucleation by microtubule organizing center


negative regulation of tubulin deacetylation


BAIP3_HUMAN BAI1-associated protein 3 (sprot)


positive regulation of neurotransmitter secretion


regulation of dense core granule exocytosis


SLIT2_HUMAN Slit homolog 2 protein (sprot)


negative regulation of leukocyte chemotaxis


negative regulation of lamellipodium assembly


negative regulation of smooth muscle cell migration


chemorepulsion involved in postnatal olfactory bulb interneuron migration


corticospinal neuron axon guidance through spinal cord


negative regulation of small GTPase mediated signal transduction


negative regulation of smooth muscle cell chemotaxis


negative regulation of mononuclear cell migration


negative regulation of neutrophil chemotaxis


negative regulation of retinal ganglion cell axon guidance


ATG12_HUMAN Ubiquitin-like protein ATG12 (sprot)


positive regulation of viral translation


LTN1_HUMAN E3 ubiquitin-protein ligase listerin (sprot)


AT10B_HUMAN Phospholipid-transporting ATPase VB (sprot)


TOM70_HUMAN Mitochondrial import receptor subunit TOM70 (sprot)


mitochondrion targeting sequence binding


protein import into mitochondrial matrix


negative regulation of cell growth involved in cardiac muscle cell development


mitochondrial outer membrane translocase complex


PKHG5_HUMAN Pleckstrin homology domain-containing family G member 5 (sprot)


MYO1D_HUMAN Unconventional myosin-Id (sprot)


early endosome to recycling endosome transport


TOX4_HUMAN TOX high mobility group box family member 4 (sprot)


RHBT1_HUMAN Rho-related BTB domain-containing protein 1 (sprot)


MICA2_HUMAN [F-actin]-monooxygenase MICAL2 (sprot)


SC24D_HUMAN Protein transport protein Sec24D (sprot)


ST65G_HUMAN STAGA complex 65 subunit gamma (sprot)


maintenance of protein location in nucleus


FCSD2_HUMAN F-BAR and double SH3 domains protein 2 (sprot)


positive regulation of Arp2/3 complex-mediated actin nucleation


UFL1_HUMAN E3 UFM1-protein ligase 1 (sprot)


regulation of intracellular estrogen receptor signaling pathway


positive regulation of glial cell proliferation


negative regulation of IRE1-mediated unfolded protein response


SRBS2_HUMAN Sorbin and SH3 domain-containing protein 2 (sprot)


cell growth involved in cardiac muscle cell development


TMCC1_HUMAN Transmembrane and coiled-coil domains protein 1 (sprot)


endoplasmic reticulum-endosome membrane contact site


PHF14_HUMAN PHD finger protein 14 (sprot)


mesenchymal cell proliferation involved in lung development


negative regulation of mesenchymal cell proliferation


negative regulation of platelet-derived growth factor receptor-alpha signaling pathway


SASH1_HUMAN SAM and SH3 domain-containing protein 1 (sprot)


positive regulation of lipopolysaccharide-mediated signaling pathway


regulation of protein K63-linked ubiquitination


regulation of protein autoubiquitination


osmolarity-sensing cation channel activity


FARP2_HUMAN FERM, ARHGEF and pleckstrin domain-containing protein 2 (sprot)


UBXN7_HUMAN UBX domain-containing protein 7 (sprot)


KLH18_HUMAN Kelch-like protein 18 (sprot)


positive regulation of mitotic cell cycle phase transition


ZN432_HUMAN Zinc finger protein 432 (sprot)


LRIG2_HUMAN Leucine-rich repeats and immunoglobulin-like domains protein 2 (sprot)


regulation of platelet-derived growth factor receptor signaling pathway


negative regulation of membrane protein ectodomain proteolysis


TOX_HUMAN Thymocyte selection-associated high mobility group box protein TOX (sprot)


CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment


positive regulation of natural killer cell differentiation


CD4-positive, alpha-beta T cell lineage commitment


CD8-positive, alpha-beta T cell lineage commitment


positive regulation of DNA demethylation


SUN1_HUMAN SUN domain-containing protein 1 (sprot)


cytoskeleton-nuclear membrane anchor activity


nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration


meiotic attachment of telomere to nuclear envelope


nuclear matrix anchoring at nuclear membrane


meiotic nuclear membrane microtubule tethering complex


PLPHP_HUMAN Pyridoxal phosphate homeostasis protein (sprot)


PRP6_HUMAN Pre-mRNA-processing factor 6 (sprot)


DKK1_HUMAN Dickkopf-related protein 1 (sprot)


cell morphogenesis involved in differentiation


negative regulation of mesodermal cell fate specification


regulation of endodermal cell fate specification


positive regulation of Wnt signaling pathway, calcium modulating pathway


regulation of synaptic transmission, glutamatergic


positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway


Wnt signaling pathway involved in somitogenesis


negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment


positive regulation of tau-protein kinase activity


regulation of dopaminergic neuron differentiation


negative regulation of Wnt-Frizzled-LRP5/6 complex assembly


positive regulation of midbrain dopaminergic neuron differentiation


negative regulation of presynapse assembly


positive regulation of Wnt signaling pathway, planar cell polarity pathway


AGRL1_HUMAN Adhesion G protein-coupled receptor L1 (sprot)


ABCA8_HUMAN ABC-type organic anion transporter ABCA8 (sprot)


positive regulation of cholesterol efflux


PCF11_HUMAN Pre-mRNA cleavage complex 2 protein Pcf11 (sprot)


NFAT5_HUMAN Nuclear factor of activated T-cells 5 (sprot)


regulation of calcineurin-NFAT signaling cascade


positive regulation of leukocyte adhesion to vascular endothelial cell


ENDD1_HUMAN Endonuclease domain-containing 1 protein (sprot)


CDK14_HUMAN Cyclin-dependent kinase 14 (sprot)


cyclin-dependent protein kinase holoenzyme complex


cytoplasmic cyclin-dependent protein kinase holoenzyme complex


GLCE_HUMAN D-glucuronyl C5-epimerase (sprot)


GLSK_HUMAN Glutaminase kidney isoform, mitochondrial (sprot)


HAUS5_HUMAN HAUS augmin-like complex subunit 5 (sprot)


ABLM3_HUMAN Actin-binding LIM protein 3 (sprot)


SLIK3_HUMAN SLIT and NTRK-like protein 3 (sprot)


neurotransmitter-gated ion channel clustering


gephyrin clustering involved in postsynaptic density assembly


RNF37_HUMAN RING finger protein 37 (sprot)


FBX21_HUMAN F-box only protein 21 (sprot)


KDM4B_HUMAN Lysine-specific demethylase 4B (sprot)


RHBT3_HUMAN Rho-related BTB domain-containing protein 3 (sprot)


SO2B1_HUMAN Solute carrier organic anion transporter family member 2B1 (sprot)


sodium-independent organic anion transmembrane transporter activity


sodium-independent organic anion transport


UBP19_HUMAN Ubiquitin carboxyl-terminal hydrolase 19 (sprot)


negative regulation of skeletal muscle tissue development


positive regulation of cell cycle process


WDR47_HUMAN WD repeat-containing protein 47 (sprot)


cerebral cortex radial glia-guided migration


detection of hot stimulus involved in thermoception


TRI37_HUMAN E3 ubiquitin-protein ligase TRIM37 (sprot)


negative regulation of centriole replication


AP2A2_HUMAN AP-2 complex subunit alpha-2 (sprot)


postsynaptic neurotransmitter receptor internalization


SC31A_HUMAN Protein transport protein Sec31A (sprot)


COPII-coated ER to Golgi transport vesicle


CMTA2_HUMAN Calmodulin-binding transcription activator 2 (sprot)


neurotransmitter receptor transport to postsynaptic membrane


CE152_HUMAN Centrosomal protein of 152 kDa (sprot)


ARHGF_HUMAN Rho guanine nucleotide exchange factor 15 (sprot)


negative regulation of synapse maturation


SLIK5_HUMAN SLIT and NTRK-like protein 5 (sprot)


cyclin-dependent protein serine/threonine kinase inhibitor activity


positive regulation of signal transduction by p53 class mediator


SOX30_HUMAN Transcription factor SOX-30 (sprot)


OR2F2_HUMAN Olfactory receptor 2F2 (sprot)


OR6B1_HUMAN Olfactory receptor 6B1 (sprot)


O4F21_HUMAN Olfactory receptor 4F21 (sprot)


UPP2_HUMAN Uridine phosphorylase 2 (sprot)


OR2A4_HUMAN Olfactory receptor 2A4 (sprot)


ZO3_HUMAN Tight junction protein ZO-3 (sprot)


INMT_HUMAN Indolethylamine N-methyltransferase (sprot)


DIRA1_HUMAN GTP-binding protein Di-Ras1 (sprot)


RPP14_HUMAN Ribonuclease P protein subunit p14 (sprot)


CCNB2_HUMAN G2/mitotic-specific cyclin-B2 (sprot)


KCNK2_HUMAN Potassium channel subfamily K member 2 (sprot)


outward rectifier potassium channel activity


positive regulation of cellular response to hypoxia


UBR5_HUMAN E3 ubiquitin-protein ligase UBR5 (sprot)


negative regulation of histone H2A K63-linked ubiquitination


negative regulation of double-strand break repair


REC8_HUMAN Meiotic recombination protein REC8 homolog (sprot)


FSBP_HUMAN Fibrinogen silencer-binding protein (sprot)


ALX3_HUMAN Homeobox protein aristaless-like 3 (sprot)


AGFG2_HUMAN Arf-GAP domain and FG repeat-containing protein 2 (sprot)


NKX22_HUMAN Homeobox protein Nkx-2.2 (sprot)


spinal cord motor neuron differentiation


spinal cord oligodendrocyte cell fate specification


ventral spinal cord interneuron fate determination


SCAF4_HUMAN SR-related and CTD-associated factor 4 (sprot)


RNA polymerase II C-terminal domain phosphoserine binding


negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled


ZN202_HUMAN Zinc finger protein 202 (sprot)


S1PR2_HUMAN Sphingosine 1-phosphate receptor 2 (sprot)


negative regulation of excitatory postsynaptic potential


negative regulation of vascular associated smooth muscle cell proliferation


NDUB6_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (sprot)


protein localization to phagophore assembly site


negative regulation of smooth muscle cell proliferation


DUS14_HUMAN Dual specificity protein phosphatase 14 (sprot)


MAP kinase tyrosine/serine/threonine phosphatase activity


TNF15_HUMAN Tumor necrosis factor ligand superfamily member 15 (sprot)


RIMB1_HUMAN Peripheral-type benzodiazepine receptor-associated protein 1 (sprot)


ARK73_HUMAN Aflatoxin B1 aldehyde reductase member 3 (sprot)


UBE4B_HUMAN Ubiquitin conjugation factor E4 B (sprot)


granzyme-mediated apoptotic signaling pathway


ZFPL1_HUMAN Zinc finger protein-like 1 (sprot)


ELP1_HUMAN Elongator complex protein 1 (sprot)


UBL3_HUMAN Ubiquitin-like protein 3 (sprot)


GBRAP_HUMAN Gamma-aminobutyric acid receptor-associated protein (sprot)


positive regulation of protein K48-linked ubiquitination


NDUA3_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (sprot)


NDUB4_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (sprot)


NDUB8_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (sprot)


CDRT1_HUMAN F-box and WD repeat domain containing protein 10B (sprot)


GAAS1_HUMAN Uncharacterized protein GAS8-AS1 (sprot)


NDUB2_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (sprot)


CAC1H_HUMAN Voltage-dependent T-type calcium channel subunit alpha-1H (sprot)


NDUA7_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (sprot)


VAMP5_HUMAN Vesicle-associated membrane protein 5 (sprot)


UNC5C_HUMAN Netrin receptor UNC5C (sprot)


netrin receptor activity involved in chemorepulsion


OAZ2_HUMAN Ornithine decarboxylase antizyme 2 (sprot)


ornithine decarboxylase inhibitor activity


negative regulation of polyamine transmembrane transport


CSPG5_HUMAN Chondroitin sulfate proteoglycan 5 (sprot)


endoplasmic reticulum tubular network organization


endoplasmic reticulum tubular network formation


KLHL2_HUMAN Kelch-like protein 2 (sprot)


RCBT2_HUMAN RCC1 and BTB domain-containing protein 2 (sprot)


ZN205_HUMAN Zinc finger protein 205 (sprot)


positive regulation of hydrogen peroxide biosynthetic process


LETM1_HUMAN Mitochondrial proton/calcium exchanger protein (sprot)


negative regulation of mitochondrial calcium ion concentration


regulation of cellular hyperosmotic salinity response


regulation of synaptic membrane adhesion


negative regulation of sprouting angiogenesis


STBD1_HUMAN Starch-binding domain-containing protein 1 (sprot)


LERL1_HUMAN Leptin receptor overlapping transcript-like 1 (sprot)


ZRAB2_HUMAN Zinc finger Ran-binding domain-containing protein 2 (sprot)


positive regulation of histamine secretion by mast cell


OR5F1_HUMAN Olfactory receptor 5F1 (sprot)


OR6A2_HUMAN Olfactory receptor 6A2 (sprot)


VENTX_HUMAN Homeobox protein VENTX (sprot)


KI20A_HUMAN Kinesin-like protein KIF20A (sprot)


LRAT_HUMAN Lecithin retinol acyltransferase (sprot)


lecithin:11-cis retinol acyltransferase activity


SPDEF_HUMAN SAM pointed domain-containing Ets transcription factor (sprot)


negative regulation of cell fate commitment


positive regulation of cell fate commitment


KIF4A_HUMAN Chromosome-associated kinesin KIF4A (sprot)


MBD4_HUMAN Methyl-CpG-binding domain protein 4 (sprot)


pyrimidine-specific mismatch base pair DNA N-glycosylase activity


MTMR5_HUMAN Myotubularin-related protein 5 (sprot)


GOSR1_HUMAN Golgi SNAP receptor complex member 1 (sprot)


KAT7_HUMAN Histone acetyltransferase KAT7 (sprot)


histone H4K16 acetyltransferase activity


histone H3K14 acetyltransferase activity


histone H3K23 acetyltransferase activity


stress-activated protein kinase signaling cascade


DNA replication-dependent chromatin disassembly


histone H3-K14 acetyltransferase complex


MRP6_HUMAN ATP-binding cassette sub-family C member 6 (sprot)


I18RA_HUMAN Interleukin-18 receptor accessory protein (sprot)


GA45G_HUMAN Growth arrest and DNA damage-inducible protein GADD45 gamma (sprot)


UCP5_HUMAN Brain mitochondrial carrier protein 1 (sprot)


KCNH1_HUMAN Potassium voltage-gated channel subfamily H member 1 (sprot)


delayed rectifier potassium channel activity


ATE1_HUMAN Arginyl-tRNA--protein transferase 1 (sprot)


PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (sprot)


negative regulation of steroid hormone biosynthetic process


5HT3B_HUMAN 5-hydroxytryptamine receptor 3B (sprot)


GRP1_HUMAN RAS guanyl-releasing protein 1 (sprot)


inflammatory response to antigenic stimulus


positive regulation of granulocyte macrophage colony-stimulating factor production


TNKS1_HUMAN Poly [ADP-ribose] polymerase tankyrase-1 (sprot)


regulation of telomere maintenance via telomerase


negative regulation of telomere maintenance via telomere lengthening


negative regulation of telomeric DNA binding


negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric


CCDB1_HUMAN Cyclin-D1-binding protein 1 (sprot)


LYPD3_HUMAN Ly6/PLAUR domain-containing protein 3 (sprot)


KCNK5_HUMAN Potassium channel subfamily K member 5 (sprot)


potassium ion export across plasma membrane


VAPB_HUMAN Vesicle-associated membrane protein-associated protein B/C (sprot)


RASL1_HUMAN RasGAP-activating-like protein 1 (sprot)


SNAPN_HUMAN SNARE-associated protein Snapin (sprot)


synaptic vesicle fusion to presynaptic active zone membrane


positive regulation of late endosome to lysosome transport


MPZL1_HUMAN Myelin protein zero-like protein 1 (sprot)


NDUC2_HUMAN NADH dehydrogenase [ubiquinone] 1 subunit C2 (sprot)


negative regulation of necrotic cell death


NDUAA_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (sprot)


FKBP9_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP9 (sprot)


CELF2_HUMAN CUGBP Elav-like family member 2 (sprot)


PAPS2_HUMAN Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (sprot)


ABCBB_HUMAN Bile salt export pump (sprot)


bile acid transmembrane transporter activity


canalicular bile acid transmembrane transporter activity


carbohydrate transmembrane transporter activity


positive regulation of bile acid secretion


regulation of bile acid metabolic process


SIX3_HUMAN Homeobox protein SIX3 (sprot)


forebrain dorsal/ventral pattern formation


regulation of cell cycle phase transition


regulation of neural precursor cell proliferation


SMC2_HUMAN Structural maintenance of chromosomes protein 2 (sprot)


positive regulation of chromosome segregation


positive regulation of chromosome condensation


ATG7_HUMAN Ubiquitin-like modifier-activating enzyme ATG7 (sprot)


TACC2_HUMAN Transforming acidic coiled-coil-containing protein 2 (sprot)


TRI16_HUMAN Tripartite motif-containing protein 16 (sprot)


positive regulation of retinoic acid receptor signaling pathway


SYFM_HUMAN Phenylalanine--tRNA ligase, mitochondrial (sprot)


ZBT7A_HUMAN Zinc finger and BTB domain-containing protein 7A (sprot)


double-strand break repair via classical nonhomologous end joining


regulation of transcription regulatory region DNA binding


OR2C1_HUMAN Olfactory receptor 2C1 (sprot)


LYPA2_HUMAN Acyl-protein thioesterase 2 (sprot)


ARI2_HUMAN E3 ubiquitin-protein ligase ARIH2 (sprot)


CXB5_HUMAN Gap junction beta-5 protein (sprot)


TFIP8_HUMAN Tumor necrosis factor alpha-induced protein 8 (sprot)


M3K6_HUMAN Mitogen-activated protein kinase kinase kinase 6 (sprot)


CCN6_HUMAN Cellular communication network factor 6 (sprot)


regulation of reactive oxygen species biosynthetic process


GDF11_HUMAN Growth/differentiation factor 11 (sprot)


spinal cord anterior/posterior patterning


negative regulation of amacrine cell differentiation


SLU7_HUMAN Pre-mRNA-splicing factor SLU7 (sprot)


second spliceosomal transesterification activity


BMP10_HUMAN Bone morphogenetic protein 10 (sprot)


receptor serine/threonine kinase binding


atrial cardiac muscle tissue morphogenesis


positive regulation of cardiac muscle cell proliferation


positive regulation of sarcomere organization


regulation of cardiac muscle hypertrophy in response to stress


positive regulation of cell proliferation involved in heart morphogenesis


AGM1_HUMAN Phosphoacetylglucosamine mutase (sprot)


GCNT3_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (sprot)


MOCS3_HUMAN Adenylyltransferase and sulfurtransferase MOCS3 (sprot)


Mo-molybdopterin cofactor biosynthetic process


molybdopterin cofactor metabolic process


PKHA9_HUMAN Putative protein PLEKHA9 (sprot)


RPGF3_HUMAN Rap guanine nucleotide exchange factor 3 (sprot)


negative regulation of syncytium formation by plasma membrane fusion


positive regulation of protein export from nucleus


positive regulation of syncytium formation by plasma membrane fusion


CD2B2_HUMAN CD2 antigen cytoplasmic tail-binding protein 2 (sprot)


MED26_HUMAN Mediator of RNA polymerase II transcription subunit 26 (sprot)


ZFYV9_HUMAN Zinc finger FYVE domain-containing protein 9 (sprot)


CNIH1_HUMAN Protein cornichon homolog 1 (sprot)


TNF6B_HUMAN Tumor necrosis factor receptor superfamily member 6B (sprot)


ZIC2_HUMAN Zinc finger protein ZIC 2 (sprot)


SOX14_HUMAN Transcription factor SOX-14 (sprot)


DEXI_HUMAN Dexamethasone-induced protein (sprot)


PIGN_HUMAN GPI ethanolamine phosphate transferase 1 (sprot)


preassembly of GPI anchor in ER membrane


BAG4_HUMAN BAG family molecular chaperone regulator 4 (sprot)


negative regulation of protein targeting to mitochondrion


AHSA1_HUMAN Activator of 90 kDa heat shock protein ATPase homolog 1 (sprot)


NPT2B_HUMAN Sodium-dependent phosphate transport protein 2B (sprot)


high-density lipoprotein particle remodeling


high-density lipoprotein particle assembly


high-density lipoprotein particle clearance


negative regulation of plasma lipoprotein oxidation


discoidal high-density lipoprotein particle


spherical high-density lipoprotein particle


LCA5L_HUMAN Lebercilin-like protein (sprot)


ATS2_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 2 (sprot)


CXB6_HUMAN Gap junction beta-6 protein (sprot)


gap junction channel activity involved in cell communication by electrical coupling


cell communication by electrical coupling


gap junction-mediated intercellular transport


PARN_HUMAN Poly(A)-specific ribonuclease PARN (sprot)


polyadenylation-dependent snoRNA 3'-end processing


TGDS_HUMAN dTDP-D-glucose 4,6-dehydratase (sprot)


PSMG1_HUMAN Proteasome assembly chaperone 1 (sprot)


cerebellar granule cell precursor proliferation


LARG1_HUMAN Xylosyl- and glucuronyltransferase LARGE1 (sprot)


FMNL1_HUMAN Formin-like protein 1 (sprot)


SGPL1_HUMAN Sphingosine-1-phosphate lyase 1 (sprot)


SIX6_HUMAN Homeobox protein SIX6 (sprot)


CNEP1_HUMAN CTD nuclear envelope phosphatase 1 (sprot)


positive regulation of triglyceride biosynthetic process


ABCA1_HUMAN Phospholipid-transporting ATPase ABCA1 (sprot)


negative regulation of macrophage derived foam cell differentiation


negative regulation of cholesterol storage


apolipoprotein A-I-mediated signaling pathway


regulation of high-density lipoprotein particle assembly


positive regulation of high-density lipoprotein particle assembly


NSA2_HUMAN Ribosome biogenesis protein NSA2 homolog (sprot)


G6PE_HUMAN GDH/6PGL endoplasmic bifunctional protein (sprot)


glucose 1-dehydrogenase (NADP+) activity


glucose 1-dehydrogenase [NAD(P)] activity


pentose-phosphate shunt, oxidative branch


regulation of cortisol biosynthetic process


SC24A_HUMAN Protein transport protein Sec24A (sprot)


SC24B_HUMAN Protein transport protein Sec24B (sprot)


regulation of establishment of planar polarity involved in neural tube closure


regulation of cargo loading into COPII-coated vesicle


AGRL2_HUMAN Adhesion G protein-coupled receptor L2 (sprot)


positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway


VNN2_HUMAN Pantetheine hydrolase VNN2 (sprot)


NPTXR_HUMAN Neuronal pentraxin receptor (sprot)


CBX6_HUMAN Chromobox protein homolog 6 (sprot)


PRAM1_HUMAN PRAME family member 1 (sprot)


PRA12_HUMAN PRAME family member 12 (sprot)


GTR10_HUMAN Solute carrier family 2, facilitated glucose transporter member 10 (sprot)


negative regulation of integrin-mediated signaling pathway


negative regulation of connective tissue growth factor production


negative regulation of proteoglycan biosynthetic process


positive regulation of proteoglycan biosynthetic process


dehydroascorbic acid transmembrane transporter activity


D-glucose transmembrane transporter activity


TYDP2_HUMAN Tyrosyl-DNA phosphodiesterase 2 (sprot)


CA105_HUMAN Uncharacterized protein C1orf105 (sprot)


SFT2B_HUMAN Vesicle transport protein SFT2B (sprot)


MPC2_HUMAN Mitochondrial pyruvate carrier 2 (sprot)


mitochondrial pyruvate transmembrane transport


inner mitochondrial membrane protein complex


MET18_HUMAN Histidine protein methyltransferase 1 homolog (sprot)


ETHE1_HUMAN Persulfide dioxygenase ETHE1, mitochondrial (sprot)


ACSL3_HUMAN Fatty acid CoA ligase Acsl3 (sprot)


medium-chain fatty acid-CoA ligase activity


positive regulation of Golgi to plasma membrane protein transport


positive regulation of phosphatidylcholine biosynthetic process


KLF8_HUMAN Krueppel-like factor 8 (sprot)


RPA1_HUMAN DNA-directed RNA polymerase I subunit RPA1 (sprot)


negative regulation of protein localization to nucleolus


YETS4_HUMAN YEATS domain-containing protein 4 (sprot)


regulation of double-strand break repair


DUS4L_HUMAN tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like (sprot)


ADCY5_HUMAN Adenylate cyclase type 5 (sprot)


G protein-coupled adenosine receptor signaling pathway


adenylate cyclase-inhibiting dopamine receptor signaling pathway


regulation of insulin secretion involved in cellular response to glucose stimulus


ZBT11_HUMAN Zinc finger and BTB domain-containing protein 11 (sprot)


CNOT4_HUMAN CCR4-NOT transcription complex subunit 4 (sprot)


regulation of megakaryocyte differentiation


STABP_HUMAN STAM-binding protein (sprot)


negative regulation of hippocampal neuron apoptotic process


FSTL3_HUMAN Follistatin-related protein 3 (sprot)


negative regulation of activin receptor signaling pathway


negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway


CPSF4_HUMAN Cleavage and polyadenylation specificity factor subunit 4 (sprot)


NFAC1_HUMAN Nuclear factor of activated T-cells, cytoplasmic 1 (sprot)


mitogen-activated protein kinase p38 binding


negative regulation of vascular associated smooth muscle cell differentiation


DIRA3_HUMAN GTP-binding protein Di-Ras3 (sprot)


regulation of gene expression by genomic imprinting


NTR2_HUMAN Neurotensin receptor type 2 (sprot)


VATG2_HUMAN V-type proton ATPase subunit G 2 (sprot)


ASML_HUMAN Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein (sprot)


ECEL1_HUMAN Endothelin-converting enzyme-like 1 (sprot)


CDS2_HUMAN Phosphatidate cytidylyltransferase 2 (sprot)


EYA4_HUMAN Eyes absent homolog 4 (sprot)


K2C75_HUMAN Keratin, type II cytoskeletal 75 (sprot)


CEP43_HUMAN Centrosomal protein 43 (sprot)


protein tyrosine kinase inhibitor activity


negative regulation of protein tyrosine kinase activity


PPR3D_HUMAN Protein phosphatase 1 regulatory subunit 3D (sprot)


regulation of glycogen catabolic process


BRD1_HUMAN Bromodomain-containing protein 1 (sprot)


MOZ/MORF histone acetyltransferase complex


APBB3_HUMAN Amyloid-beta A4 precursor protein-binding family B member 3 (sprot)


RPP29_HUMAN Ribonuclease P protein subunit p29 (sprot)


LY86_HUMAN Lymphocyte antigen 86 (sprot)


HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 (sprot)


CXL14_HUMAN C-X-C motif chemokine 14 (sprot)


RAB3D_HUMAN Ras-related protein Rab-3D (sprot)


positive regulation of regulated secretory pathway


ERR2_HUMAN Steroid hormone receptor ERR2 (sprot)


positive regulation of transcription involved in G2/M transition of mitotic cell cycle


SNP29_HUMAN Synaptosomal-associated protein 29 (sprot)


CRTAM_HUMAN Cytotoxic and regulatory T-cell molecule (sprot)


positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target


lymphocyte migration into lymphoid organs


regulation of CD8-positive, alpha-beta T cell activation


PM2P2_HUMAN Putative postmeiotic segregation increased 2-like protein 2 (sprot)


OXSR1_HUMAN Serine/threonine-protein kinase OSR1 (sprot)


chemokine (C-X-C motif) ligand 12 signaling pathway


GGPPS_HUMAN Geranylgeranyl pyrophosphate synthase (sprot)


geranyl diphosphate biosynthetic process


geranylgeranyl diphosphate biosynthetic process


farnesyl diphosphate biosynthetic process


FGF19_HUMAN Fibroblast growth factor 19 (sprot)


negative regulation of bile acid biosynthetic process


maternal process involved in parturition


RAB36_HUMAN Ras-related protein Rab-36 (sprot)


HS74L_HUMAN Heat shock 70 kDa protein 4L (sprot)


PTBP3_HUMAN Polypyrimidine tract-binding protein 3 (sprot)


TBCD8_HUMAN TBC1 domain family member 8 (sprot)


positive regulation of cellular defense response


negative regulation of macrophage proliferation


negative regulation of immunoglobulin production


positive regulation of immunoglobulin production


negative regulation of leukocyte migration


negative regulation of T-helper 1 type immune response


positive regulation of type 2 immune response


positive regulation of interleukin-5 production


positive regulation of MHC class I biosynthetic process


STR3N_HUMAN STARD3 N-terminal-like protein (sprot)


vesicle tethering to endoplasmic reticulum


LSM8_HUMAN U6 snRNA-associated Sm-like protein LSm8 (sprot)


ZN682_HUMAN Zinc finger protein 682 (sprot)


AP2A1_HUMAN AP-2 complex subunit alpha-1 (sprot)


negative regulation of hyaluronan biosynthetic process


clathrin coat of trans-Golgi network vesicle


DDX58_HUMAN Antiviral innate immune response receptor RIG-I (sprot)


positive regulation of myeloid dendritic cell cytokine production


regulation of type III interferon production


positive regulation of response to cytokine stimulus


ZMYM6_HUMAN Zinc finger MYM-type protein 6 (sprot)


STAU1_HUMAN Double-stranded RNA-binding protein Staufen homolog 1 (sprot)


positive regulation by virus of viral protein levels in host cell


GPR75_HUMAN Probable G-protein coupled receptor 75 (sprot)


TTC4_HUMAN Tetratricopeptide repeat protein 4 (sprot)


NDST3_HUMAN Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (sprot)


[heparan sulfate]-glucosamine N-sulfotransferase activity


heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process


TM50A_HUMAN Transmembrane protein 50A (sprot)


CAVN2_HUMAN Caveolae-associated protein 2 (sprot)


growth plate cartilage chondrocyte proliferation


sequestering of BMP in extracellular matrix


negative regulation of mesoderm development


BAG2_HUMAN BAG family molecular chaperone regulator 2 (sprot)


adenyl-nucleotide exchange factor activity


positive regulation of protein processing


negative regulation of ubiquitin protein ligase activity


BAG3_HUMAN BAG family molecular chaperone regulator 3 (sprot)


negative regulation of striated muscle cell apoptotic process


negative regulation of transcription from RNA polymerase II promoter in response to stress


M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 (sprot)


positive regulation of ARF protein signal transduction


positive regulation of focal adhesion disassembly


DCMC_HUMAN Malonyl-CoA decarboxylase, mitochondrial (sprot)


positive regulation of fatty acid oxidation


QORL1_HUMAN Quinone oxidoreductase-like protein 1 (sprot)


AIFM1_HUMAN Apoptosis-inducing factor 1, mitochondrial (sprot)


oxidoreductase activity, acting on NAD(P)H


mitochondrial respiratory chain complex assembly


protein import into mitochondrial intermembrane space


positive regulation of necroptotic process


cellular response to oxygen-glucose deprivation


xenobiotic transport across blood-nerve barrier


establishment of endothelial intestinal barrier


CLIC3_HUMAN Chloride intracellular channel protein 3 (sprot)


EMAL2_HUMAN Echinoderm microtubule-associated protein-like 2 (sprot)


negative regulation of microtubule polymerization


LATS1_HUMAN Serine/threonine-protein kinase LATS1 (sprot)


regulation of ubiquitin-dependent protein catabolic process


GNA14_HUMAN Guanine nucleotide-binding protein subunit alpha-14 (sprot)


GLP2R_HUMAN Glucagon-like peptide 2 receptor (sprot)


ANGL1_HUMAN Angiopoietin-related protein 1 (sprot)


GUC1C_HUMAN Guanylyl cyclase-activating protein 3 (sprot)


UCP4_HUMAN Mitochondrial uncoupling protein 4 (sprot)


NUD14_HUMAN Uridine diphosphate glucose pyrophosphatase NUDT14 (sprot)


regulation of calcium ion transmembrane transport


BPNT1_HUMAN 3'(2'),5'-bisphosphate nucleotidase 1 (sprot)


SNAI1_HUMAN Zinc finger protein SNAI1 (sprot)


negative regulation of cell differentiation involved in embryonic placenta development


FADS2_HUMAN Acyl-CoA 6-desaturase (sprot)


DDAH2_HUMAN N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (sprot)


G6B_HUMAN Megakaryocyte and platelet inhibitory receptor G6b (sprot)


LY66C_HUMAN Lymphocyte antigen 6 complex locus protein G6c (sprot)


LY66D_HUMAN Lymphocyte antigen 6 complex locus protein G6d (sprot)


ABHGA_HUMAN Phosphatidylserine lipase ABHD16A (sprot)


GPAN1_HUMAN G patch domain and ankyrin repeat-containing protein 1 (sprot)


CF047_HUMAN Uncharacterized protein C6orf47 (sprot)


FRITZ_HUMAN WD repeat-containing and planar cell polarity effector protein fritz homolog (sprot)


TXD12_HUMAN Thioredoxin domain-containing protein 12 (sprot)


protein-disulfide reductase (glutathione) activity


DLGP3_HUMAN Disks large-associated protein 3 (sprot)


positive regulation of smooth muscle cell differentiation


regulation of vascular associated smooth muscle cell dedifferentiation


TRUB2_HUMAN Pseudouridylate synthase TRUB2, mitochondrial (sprot)


positive regulation of mitochondrial translation


ECD_HUMAN Protein ecdysoneless homolog (sprot)


MOT3_HUMAN Monocarboxylate transporter 3 (sprot)


OR2H2_HUMAN Olfactory receptor 2H2 (sprot)


TTLL1_HUMAN Polyglutamylase complex subunit TTLL1 (sprot)


immune response in nasopharyngeal-associated lymphoid tissue


cerebellar Purkinje cell differentiation


negative regulation of flagellated sperm motility


SYF2_HUMAN Pre-mRNA-splicing factor SYF2 (sprot)


CBX7_HUMAN Chromobox protein homolog 7 (sprot)


developmental process involved in reproduction


TGM3L_HUMAN Protein-glutamine gamma-glutamyltransferase 6 (sprot)


TBX18_HUMAN T-box transcription factor TBX18 (sprot)


negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation


EOMES_HUMAN Eomesodermin homolog (sprot)


CD8-positive, alpha-beta T cell differentiation involved in immune response


cell differentiation involved in embryonic placenta development


mesodermal to mesenchymal transition involved in gastrulation


NCTR2_HUMAN Natural cytotoxicity triggering receptor 2 (sprot)


TBX6_HUMAN T-box transcription factor TBX6 (sprot)


negative regulation of neuron maturation


somite rostral/caudal axis specification


ONEC2_HUMAN One cut domain family member 2 (sprot)


peripheral nervous system neuron development


positive regulation of mesenchymal stem cell migration


folic acid-containing compound metabolic process


histidine catabolic process to glutamate and formamide


histidine catabolic process to glutamate and formate


ITGBL_HUMAN Integrin beta-like protein 1 (sprot)


FBLN4_HUMAN EGF-containing fibulin-like extracellular matrix protein 2 (sprot)


aorta smooth muscle tissue morphogenesis


regulation of collagen fibril organization


positive regulation of collagen fibril organization


positive regulation of aortic smooth muscle cell differentiation


positive regulation of smooth muscle cell-matrix adhesion


SG1D1_HUMAN Secretoglobin family 1D member 1 (sprot)


SG1D2_HUMAN Secretoglobin family 1D member 2 (sprot)


LGI1_HUMAN Leucine-rich glioma-inactivated protein 1 (sprot)


positive regulation of synaptic transmission


activating MHC class I receptor activity


positive regulation of natural killer cell cytokine production


positive regulation of natural killer cell mediated immune response to tumor cell


negative regulation of CD4-positive, alpha-beta T cell costimulation


negative regulation of adaptive immune memory response


positive regulation of endothelial cell apoptotic process


BMP15_HUMAN Bone morphogenetic protein 15 (sprot)


IGSF6_HUMAN Immunoglobulin superfamily member 6 (sprot)


S1PR4_HUMAN Sphingosine 1-phosphate receptor 4 (sprot)


RECK_HUMAN Reversion-inducing cysteine-rich protein with Kazal motifs (sprot)


regulation of establishment of blood-brain barrier


negative regulation of metalloendopeptidase activity


MBD3_HUMAN Methyl-CpG-binding domain protein 3 (sprot)


DNA methylation-dependent heterochromatin formation


TOP3B_HUMAN DNA topoisomerase 3-beta-1 (sprot)


DNA topoisomerase type I (single strand cut, ATP-independent) activity


DNA topoisomerase III-beta-TDRD3 complex


TCL1B_HUMAN T-cell leukemia/lymphoma protein 1B (sprot)


NUDT3_HUMAN Diphosphoinositol polyphosphate phosphohydrolase 1 (sprot)


inositol diphosphate tetrakisphosphate diphosphatase activity


inositol diphosphate pentakisphosphate diphosphatase activity


diadenosine polyphosphate catabolic process


diphosphoinositol polyphosphate catabolic process


F107A_HUMAN Actin-associated protein FAM107A (sprot)


CH25H_HUMAN Cholesterol 25-hydroxylase (sprot)


negative regulation of fusion of virus membrane with host plasma membrane


AGR2_HUMAN Anterior gradient protein 2 homolog (sprot)


positive regulation of developmental growth


positive regulation of PERK-mediated unfolded protein response


DRC4_HUMAN Dynein regulatory complex subunit 4 (sprot)


cilium movement involved in cell motility


positive regulation of protein localization to cilium


APCL_HUMAN Adenomatous polyposis coli protein 2 (sprot)


I18BP_HUMAN Interleukin-18-binding protein (sprot)


BCL10_HUMAN B-cell lymphoma/leukemia 10 (sprot)


positive regulation of lymphotoxin A production


positive regulation of mast cell cytokine production


general transcription initiation factor binding


negative regulation of mature B cell apoptotic process


NDUBA_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (sprot)


PPR17_HUMAN Protein phosphatase 1 regulatory subunit 17 (sprot)


CX001_HUMAN Putative transmembrane protein CXorf1 (sprot)


HAND1_HUMAN Heart- and neural crest derivatives-expressed protein 1 (sprot)


CLPT1_HUMAN Putative lipid scramblase CLPTM1 (sprot)


regulation of T cell differentiation in thymus


ZBED1_HUMAN E3 SUMO-protein ligase ZBED1 (sprot)


MOC2B_HUMAN Molybdopterin synthase catalytic subunit (sprot)


molybdopterin cofactor biosynthetic process


TOM40_HUMAN Mitochondrial import receptor subunit TOM40 homolog (sprot)


PX11B_HUMAN Peroxisomal membrane protein 11B (sprot)


PAK4_HUMAN Serine/threonine-protein kinase PAK 4 (sprot)


planar cell polarity pathway involved in axis elongation


Wnt signaling pathway, calcium modulating pathway


positive regulation of transforming growth factor beta2 production


convergent extension involved in axis elongation


planar cell polarity pathway involved in gastrula mediolateral intercalation


negative regulation of cartilage development


negative regulation of fibroblast growth factor production


DNAL4_HUMAN Dynein axonemal light chain 4 (sprot)


CHK2_HUMAN Serine/threonine-protein kinase Chk2 (sprot)


DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator


negative regulation of DNA damage checkpoint


APBA3_HUMAN Amyloid-beta A4 precursor protein-binding family A member 3 (sprot)


ACL6A_HUMAN Actin-like protein 6A (sprot)


positive regulation of telomere maintenance in response to DNA damage


CCNE2_HUMAN G1/S-specific cyclin-E2 (sprot)


B3GT4_HUMAN Beta-1,3-galactosyltransferase 4 (sprot)


NSD2_HUMAN Histone-lysine N-methyltransferase NSD2 (sprot)


histone H4K20 methyltransferase activity


histone H3K36 methyltransferase activity


histone H3K36 dimethyltransferase activity


regulation of double-strand break repair via nonhomologous end joining


HMHB1_HUMAN Minor histocompatibility protein HB-1 (sprot)


ADH1B_HUMAN All-trans-retinol dehydrogenase [NAD(+)] ADH1B (sprot)


alcohol dehydrogenase activity, zinc-dependent


ADH1G_HUMAN Alcohol dehydrogenase 1C (sprot)


LDHA_HUMAN L-lactate dehydrogenase A chain (sprot)


AL1A1_HUMAN Aldehyde dehydrogenase 1A1 (sprot)


glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity


gamma-aminobutyric acid biosynthetic process


DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial (sprot)


glutamate dehydrogenase [NAD(P)+] activity


glutamate dehydrogenase (NADP+) activity


DYR_HUMAN Dihydrofolate reductase (sprot)


mRNA regulatory element binding translation repressor activity


regulation of removal of superoxide radicals


NB5R3_HUMAN NADH-cytochrome b5 reductase 3 (sprot)


cytochrome-b5 reductase activity, acting on NAD(P)H


GSHR_HUMAN Glutathione reductase, mitochondrial (sprot)


COX1_HUMAN Cytochrome c oxidase subunit 1 (sprot)


COX2_HUMAN Cytochrome c oxidase subunit 2 (sprot)


positive regulation of necrotic cell death


COX3_HUMAN Cytochrome c oxidase subunit 3 (sprot)


tyrosine biosynthetic process, by oxidation of phenylalanine


SODC_HUMAN Superoxide dismutase [Cu-Zn] (sprot)


peripheral nervous system myelin maintenance


negative regulation of developmental process


relaxation of vascular associated smooth muscle


negative regulation of reproductive process


FA8_HUMAN Coagulation factor VIII (sprot)


OTC_HUMAN Ornithine transcarbamylase, mitochondrial (sprot)


F13A_HUMAN Coagulation factor XIII A chain (sprot)


blood coagulation, fibrin clot formation


PNPH_HUMAN Purine nucleoside phosphorylase (sprot)


positive regulation of alpha-beta T cell differentiation


HPRT_HUMAN Hypoxanthine-guanine phosphoribosyltransferase (sprot)


AATM_HUMAN Aspartate aminotransferase, mitochondrial (sprot)


glutamate catabolic process to aspartate


glutamate catabolic process to 2-oxoglutarate


ABL1_HUMAN Tyrosine-protein kinase ABL1 (sprot)


negative regulation of phospholipase C activity


transitional one stage B cell differentiation


regulation of microtubule polymerization


platelet-derived growth factor receptor-beta signaling pathway


positive regulation of hydrogen peroxide-mediated programmed cell death


positive regulation of establishment of T cell polarity


protein localization to cytoplasmic microtubule plus-end


positive regulation of microtubule binding


positive regulation of actin filament binding


regulation of modification of synaptic structure


positive regulation of blood vessel branching


EGFR_HUMAN Epidermal growth factor receptor (sprot)


nitric-oxide synthase regulator activity


transmembrane receptor protein tyrosine kinase activity


epidermal growth factor receptor activity


protein tyrosine kinase activator activity


negative regulation of epidermal growth factor receptor signaling pathway


regulation of peptidyl-tyrosine phosphorylation


positive regulation of protein kinase C activity


negative regulation of cardiocyte differentiation


multivesicular body, internal vesicle lumen


MOS_HUMAN Proto-oncogene serine/threonine-protein kinase mos (sprot)


establishment of meiotic spindle orientation


negative regulation of metaphase/anaphase transition of meiotic cell cycle


PGK1_HUMAN Phosphoglycerate kinase 1 (sprot)


protein-disulfide reductase (NAD(P)) activity


KAD1_HUMAN Adenylate kinase isoenzyme 1 (sprot)


nucleoside triphosphate biosynthetic process


nucleobase-containing small molecule interconversion


negative regulation of platelet activation


positive regulation of blood coagulation


positive regulation of lipid kinase activity


positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway


C1R_HUMAN Complement C1r subcomponent (sprot)


negative regulation of oxidoreductase activity


negative regulation of hydrogen peroxide catabolic process


HPTR_HUMAN Haptoglobin-related protein (sprot)


complement activation, alternative pathway


biological process involved in interaction with symbiont


negative regulation of cell-cell adhesion mediated by cadherin


FA12_HUMAN Coagulation factor XII (sprot)


positive regulation of plasminogen activation


UROK_HUMAN Urokinase-type plasminogen activator (sprot)


regulation of signaling receptor activity


negative regulation of plasminogen activation


regulation of smooth muscle cell migration


urokinase plasminogen activator signaling pathway


regulation of smooth muscle cell-matrix adhesion


protein complex involved in cell-matrix adhesion


TPA_HUMAN Tissue-type plasminogen activator (sprot)


cellular response to follicle-stimulating hormone stimulus


cellular response to luteinizing hormone stimulus


trans-synaptic signaling by BDNF, modulating synaptic transmission


renin-angiotensin regulation of aldosterone production


positive regulation of germinal center formation


regulation of cell-cell adhesion mediated by integrin


positive regulation of smooth muscle contraction


positive regulation of calcium-mediated signaling


negative regulation of adenosine receptor signaling pathway


negative regulation of thymocyte apoptotic process


ATP6_HUMAN ATP synthase subunit a (sprot)


proton-transporting ATP synthase complex, coupling factor F(o)


positive regulation of synaptic transmission, GABAergic


positive regulation of cellular pH reduction


positive regulation of dipeptide transmembrane transport


ASSY_HUMAN Argininosuccinate synthase (sprot)


negative regulation of leukocyte cell-cell adhesion


OAS1_HUMAN 2'-5'-oligoadenylate synthase 1 (sprot)


negative regulation of type I interferon-mediated signaling pathway


ISK1_HUMAN Serine protease inhibitor Kazal-type 1 (sprot)


negative regulation of nitric oxide mediated signal transduction


negative regulation of peptidyl-tyrosine phosphorylation


positive regulation of pancreatic juice secretion


positive regulation of peptide hormone secretion


negative regulation of serine-type endopeptidase activity


maintenance of gastrointestinal epithelium


regulation of blood volume by renin-angiotensin


regulation of renal output by angiotensin


maintenance of blood vessel diameter homeostasis by renin-angiotensin


positive regulation of extracellular matrix constituent secretion


G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger


positive regulation of activation of Janus kinase activity


positive regulation of cardiac muscle cell apoptotic process


response to muscle activity involved in regulation of muscle adaptation


positive regulation of NAD(P)H oxidase activity


negative regulation of tissue remodeling


positive regulation of renal sodium excretion


regulation of transmission of nerve impulse


regulation of extracellular matrix assembly


positive regulation of gap junction assembly


positive regulation of L-lysine import across plasma membrane


positive regulation of L-arginine import across plasma membrane


positive regulation of CoA-transferase activity


brain-derived neurotrophic factor binding


negative regulation of complement activation, lectin pathway


acute inflammatory response to antigenic stimulus


negative regulation of endopeptidase activity