neuronal ion channel clustering

The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.


regulation of glial cell apoptotic process

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Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.


regulation of protein serine/threonine kinase activity

Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.


regulation of Schwann cell proliferation

Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.


Schwann cell migration

The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.


regulation of circulating fibrinogen levels

Any process that modulates the quantity of fibrinogen circulating in the bloodstream.


positive regulation of cell cycle checkpoint

Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.


transmembrane receptor protein tyrosine phosphatase signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with the regulation of a downstream cellular process, e.g. transcription.


phosphate-containing compound metabolic process

The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.


retinol binding

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Binding to retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.


negative regulation of cargo loading into COPII-coated vesicle

Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.


platelet alpha granule membrane

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The lipid bilayer surrounding the platelet alpha granule.


positive regulation of T-helper cell differentiation

Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.


somatostatin receptor activity

Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).


nephric duct development

The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.


regulation of branch elongation involved in ureteric bud branching

Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.


negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis

Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.


nephric duct formation

The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.


ureteric bud elongation

The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.


nose morphogenesis

The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).


histone deacetylase inhibitor activity

Binds to and stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.


negative regulation of Schwann cell proliferation

Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.


positive regulation of synaptic plasticity

A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.


taurine transmembrane transporter activity

Enables the transfer of taurine from one side of a membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats.


beta-alanine transmembrane transporter activity

Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.


taurine transport

The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


beta-alanine transport

The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


thromboxane receptor activity

Combining with a thromboxane (TXA) to initiate a change in cell activity.


MHC protein binding

Binding to a major histocompatibility complex molecule; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.


DNA nucleotidylexotransferase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


response to interferon-alpha

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.


regulation of lipid catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.


steroid receptor RNA activator RNA binding

Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.


thyroid-stimulating hormone receptor activity

Combining with thyroid-stimulating hormone to initiate a change in cell activity.


forward locomotion

Anterior movement of an organism, following the direction of the head of the animal.


detection of muscle stretch

The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal.


positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.


podosome ring

The ring structure surrounding the podosome core, containing proteins such as vinculin and talin.


nephron tubule development

The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.


renal vesicle induction

Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.


metanephric nephron morphogenesis

The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.


positive regulation of vascular endothelial growth factor production

Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.


positive regulation of chronic inflammatory response to non-antigenic stimulus

Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.


cysteine transport

The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


melanocortin receptor activity

Combining with melanocortin to initiate a change in cell activity.


positive regulation of superoxide dismutase activity

Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.


negative regulation of DNA biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.


regulation of stress-activated MAPK cascade

Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.


fibrinogen binding

Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.


positive regulation of long-term neuronal synaptic plasticity

A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.


calcium ion sensor activity

Binding to and responding, e.g. by conformational change, to changes in the cellular level of calcium ions (Ca2+).


synchronous neurotransmitter secretion

Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.


calcium ion transmembrane import into cytosol

A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.


T cell selection

The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.


cytidylate kinase activity

Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.


L-ornithine import across plasma membrane

The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.


cationic amino acid transporter 2 isoform 2 (mouse)

A cationic amino acid transporter 2 isoform 1 that is encoded in the genome of mouse.


L-lysine import across plasma membrane

The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.


high-affinity L-ornithine transmembrane transporter activity

Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


high-affinity lysine transmembrane transporter activity

Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


high-affinity L-arginine transmembrane transporter activity

Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


L-arginine import across plasma membrane

The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.


low-affinity L-arginine transmembrane transporter activity

Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


L-ornithine transmembrane transport

The directed movement of L-ornithine across a membrane.


laminin-5 complex

A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.


generation of ovulation cycle rhythm

The process which controls the timing of the type of sexual cycle seen in female mammals.


positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.


laminin-3 complex

A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.


structural constituent of synapse-associated extracellular matrix

The action of a molecule that contributes to the structural integrity of the extracellular matrix of the perisynaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.


adenine DNA glycosylase isoform hGamma-3 (human)

An adenine DNA glycosylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF7-6.


G-rich single-stranded DNA binding

Binding to G-rich, single-stranded DNA.


double-strand break repair via synthesis-dependent strand annealing

SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break.


SLBP_HUMAN Histone RNA hairpin-binding protein (sprot)

A histone RNA hairpin-binding protein that is encoded in the genome of human.


ABLM1_HUMAN Actin-binding LIM protein 1 (sprot)

An actin-binding LIM protein 1 that is encoded in the genome of human.


ABLM3_HUMAN Actin-binding LIM protein 3 (sprot)

An actin-binding LIM protein 3 that is encoded in the genome of human.


ABLM2_HUMAN Actin-binding LIM protein 2 (sprot)

An actin-binding LIM protein 2 that is encoded in the genome of human.


ARC_HUMAN Activity-regulated cytoskeleton-associated protein (sprot)

An activity-regulated cytoskeleton-associated protein that is encoded in the genome of human.


SH3G3_HUMAN Endophilin-A3 (sprot)

An endophilin-A3 that is encoded in the genome of human.


Cyanamide

A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by an amino group.


polyphenol

Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group.


Acetovanillone

An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.


Sepiapterin

A sepiapterin with L configuration.


UBXN1_HUMAN UBX domain-containing protein 1 (sprot)

A UBX domain-containing protein 1 that is encoded in the genome of human.


receptor tyrosine-protein kinase erbB-3 isoform h1 (human)

A receptor tyrosine-protein kinase erbB-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21860-1.


NRG2_HUMAN Pro-neuregulin-2, membrane-bound isoform (sprot)

A pro-neuregulin-2, membrane-bound isoform that is encoded in the genome of human.


neuregulin-1 type III-beta3 (human)

A neuregulin-1 type III-beta3 that is encoded in the genome of human.


Sebacic Acid

An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane.


Dodecanedioic acid

An alpha,omega-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids.


Undecanoic acid

A straight-chain, eleven-carbon saturated medium-chain fatty acid found in body fluids; the most fungitoxic of the C7:0 - C18:0 fatty acid series.


A zwitterion resulting from the transfer of a proton for the carboxy group to the amino group of the L-gamma-glutamyl residue of S-methylglutathione.


MICU1_HUMAN Calcium uptake protein 1, mitochondrial (sprot)

A calcium uptake protein 1, mitochondrial that is encoded in the genome of human.


MCU_HUMAN Calcium uniporter protein, mitochondrial (sprot)

A calcium uniporter protein, mitochondrial that is encoded in the genome of human.


MCUB_HUMAN Calcium uniporter regulatory subunit MCUb, mitochondrial (sprot)

A calcium uniporter regulatory subunit MCUb, mitochondrial that is encoded in the genome of human.


MICU3_HUMAN Calcium uptake protein 3, mitochondrial (sprot)

A calcium uptake protein 3, mitochondrial that is encoded in the genome of human.


MICU2_HUMAN Calcium uptake protein 2, mitochondrial (sprot)

A calcium uptake protein 2, mitochondrial that is encoded in the genome of human.


IL7_HUMAN Interleukin-7 (sprot)

An interleukin-7 that is encoded in the genome of human.


IL7RA_HUMAN Interleukin-7 receptor subunit alpha (sprot)

An interleukin-7 receptor subunit alpha that is encoded in the genome of human.


Pyrazinamide

A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis.


Gedunin

A pentacyclic triterpenoid natural product found  particularly in Azadirachta indica and Cedrela odorata.


Salicylamide

The simplest member of the class of salicylamides derived from salicylic acid.


Tolazoline

A member of the class of imidazoles that is 4,5-dihydro-1H-imidazole substituted by a benzyl group.


Kuwanon G

A tetrahydroxyflavone isolated from the root barks of Morus alba and has been shown to exhibit anti-inflammatory activity.


KLKB1_HUMAN Plasma kallikrein (sprot)

A plasma kallikrein that is encoded in the genome of human.


anionic phospholipid

Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-).


DEF6_HUMAN Defensin-6 (sprot)

A protein that is a translation product of the DEFA6 gene in human.


cardiolipin biosynthetic process

The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.


INOSITOL 1,2,4,5,6-PENTAPHOSPHATE

A myo-inositol pentakisphosphate comprising 1D-myo-inositol having the five phosphate groups placed in the 1-' 2-' 4-, 5- and 6-positions.


Coenzyme Q6

A ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.


A ubiquinol in which the polyprenyl substituent is hexaprenyl.


Betaine aldehyde

A quaternary ammonium ion that is nitrogen substituted by three methyl groups and a 2-oxoethyl group. It is an intermediate in the metabolism of amino acids like glycine, serine and threonine.


aflatoxin B1 8,9-dihydrodiol

An aflatoxin B1 compound formed via enzymic epoxidation of aflatoxin B1 followed by non-enzymic hydrolysis.


Fenoterol

A member of the class  resorcinols that is 5-(1-hydroxyethyl)benzene-1,3-diol in which one of the methyl hydrogens is replaced by a 1-(4-hydroxyphenyl)propan-2-amino group. A beta2-adrenergic agonist, it is used (as the hydrobromide salt) as a bronchodilator in the management of reversible airway obstruction.


Trimethylarsine

An arsine that is arsane in which each of the hydrogens is substituted by a methyl group.


1'-Acetoxychavicol acetate

An  acetate ester that is chavicol acetate substituted by an acetoxy group at position 1'.


Aminoguanidine

A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.


Ethoxyquin

A quinoline that is 1,2-dihydroquinoline bearing three methyl substituents at position 2, 2 and 4 as well as an ethoxy substituent at position 6.


A dichlorobiphenyl that is p-dichlorobenzene in which one of the hydrogens has been replaced by a phenyl group.


Naringin

A disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage.


Oroxylin A

A dihydroxy- and monomethoxy-flavone in which the hydroxy groups are positioned at C-5 and C-7 and the methoxy group is at C-6.


Cephaloridine

A cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C.


Amoxicillin trihydrate

A hydrate that is the trihydrate form of amoxicillin; a semisynthetic antibiotic, used either alone or in combination with potassium clavulanate (under the trade name Augmentin) for treatment of a variety of bacterial infections.


Oxytetracycline

A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae.


CHLORTETRACYCLINE

A member of the class of tetracyclines with formula C22H23ClN2O8 isolated from Streptomyces aureofaciens.


A member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3 and 5 by 4-methoxyphenyl, trifluoromethyl and 4-chlorophenyl groups, respectively. Unlike many members of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors, SC-560 is selective for COX-1.


Estra-1,3,5(10)-triene-3,17-diol (17beta)-, hydrogen sulfate


Ceftibuten

A third-generation cephalosporin antibiotic with a [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino substituent at the 7 position of the cephem skeleton. An orally-administered agent, ceftibuten is used as the dihydrate to treat urinary-tract and respiratory-tract infections.


Ceftizoxime

A parenteral third-generation cephalosporin, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position.


4-Methylumbelliferone sulfate

A member of the class of coumarins that is umbelliferone sulfate which carries a methyl group at position 4. It is a metabolite of 4-methylumbelliferone.


Cefotiam

A cephalosporin with ({1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl}sulfanyl)methyl and (2-amino-1,3-thiazol-4-yl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. A third generation beta-lactam cephalosporin antibiotic, it is active against a broad spectrum of both Gram positive and Gram negative bacteria.


Cefaclor

A cephalosporin bearing chloro and (R)-2-amino-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton.


Losartan carboxylic acid

A biphenylyltetrazole that is losartan with the hydroxymethyl group at position 5 on the imidazole ring replaced with a carboxylic acid.


Tylosin

A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. It is found naturally as a fermentation product of Streptomyces fradiae.


Cefdinir

A cephalosporin compound having 7beta-2-(2-amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino- and 3-vinyl side groups.


5-Methoxyindole-3-acetic acid

A member of the class of indole-3-acetic acids in which the hydrogen at position 5 of indole-3-acetic acid has been replaced by a methoxy group.


Tilmicosin

A macrolide antibiotic with formula C46H80N2O13. It is used for the treatment of respiratory disease in cattle at high risk of developing bovine respiratory disease associated with Mannheimia haemolytica.


Vanillylmandelic acid

An aromatic ether that is the 3-O-methyl ether of 3,4-dihydroxymandelic acid.


An aromatic ketone that is acetophenone in which one of the ortho hydrogens of the phenyl group has been replaced by an amino group.


An organophosphate oxoanion obtained by deprotonation of the diphosphate OH groups of 8-oxo-dADP.


An organophosphate oxoanion arising from deprotonation of the three diphosphate OH groups of 8-oxo-dGDP; major species at pH 7.3.


An organophosphate oxoanion resulting from the removal of two protons from the phosphate group of 8-oxo-dGMP.


An organophosphate oxoanion obtained by deprotonation of the diphosphate OH groups of 8-oxo-dAMP.


An organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of 2-oxo-AMP.


An organophosphate oxoanion that is the dianion of 2'-deoxy-2-hydroxyadenosine 5'-monophosphate arising from deprotonation of both OH groups of the phosphate.


benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone


Acetoin

A methyl ketone that is butan-2-one substituted by a hydroxy group at position 3.


Lanthionine

The L-enantiomer of lanthionine.


JUNO_HUMAN Sperm-egg fusion protein Juno (sprot)

A sperm-egg fusion protein Juno that is encoded in the genome of human.


PSCA_HUMAN Prostate stem cell antigen (sprot)

A prostate stem cell antigen that is encoded in the genome of human.


TECTA_HUMAN Alpha-tectorin (sprot)

An alpha-tectorin that is encoded in the genome of human.


LY6H_HUMAN Lymphocyte antigen 6H (sprot)

A lymphocyte antigen 6H that is encoded in the genome of human.


CNTN5_HUMAN Contactin-5 (sprot)

A contactin-5 that is encoded in the genome of human.


LY66C_HUMAN Lymphocyte antigen 6 complex locus protein G6c (sprot)

A lymphocyte antigen 6 complex locus protein G6c that is encoded in the genome of human.


RECK_HUMAN Reversion-inducing cysteine-rich protein with Kazal motifs (sprot)

A reversion-inducing cysteine-rich protein with Kazal motifs that is encoded in the genome of human.


THY1_HUMAN Thy-1 membrane glycoprotein (sprot)

A Thy-1 membrane glycoprotein that is encoded in the genome of human.


TRFM_HUMAN Melanotransferrin (sprot)

A melanotransferrin that is encoded in the genome of human.


CBPM_HUMAN Carboxypeptidase M (sprot)

A carboxypeptidase M that is encoded in the genome of human.


CD52_HUMAN CAMPATH-1 antigen (sprot)

A CAMPATH-1 antigen that is encoded in the genome of human.


GP2_HUMAN Pancreatic secretory granule membrane major glycoprotein GP2 (sprot)

A pancreatic secretory granule membrane major glycoprotein GP2 that is encoded in the genome of human.


MSLN_HUMAN Mesothelin (sprot)

A mesothelin that is encoded in the genome of human.


LSAMP_HUMAN Limbic system-associated membrane protein (sprot)

A limbic system-associated membrane protein that is encoded in the genome of human.


NAR3_HUMAN Ecto-ADP-ribosyltransferase 3 (sprot)

An ecto-ADP-ribosyltransferase 3 that is encoded in the genome of human.


CEAM7_HUMAN Carcinoembryonic antigen-related cell adhesion molecule 7 (sprot)

A carcinoembryonic antigen-related cell adhesion molecule 7 that is encoded in the genome of human.


LY6D_HUMAN Lymphocyte antigen 6D (sprot)

A lymphocyte antigen 6D that is encoded in the genome of human.


OPCM_HUMAN Opioid-binding protein/cell adhesion molecule (sprot)

An opioid-binding protein/cell adhesion molecule that is encoded in the genome of human.


LY6E_HUMAN Lymphocyte antigen 6E (sprot)

A lymphocyte antigen 6E that is encoded in the genome of human.


LY6K_HUMAN Lymphocyte antigen 6K (sprot)

A lymphocyte antigen 6K that is encoded in the genome of human.


NRN1L_HUMAN Neuritin-like protein (sprot)

A neuritin-like protein that is encoded in the genome of human.


SPRN_HUMAN Shadow of prion protein (sprot)

A shadow of prion protein that is encoded in the genome of human.


ULBP6_HUMAN UL16-binding protein 6 (sprot)

A UL16-binding protein 6 that is encoded in the genome of human.


ULBP5_HUMAN UL-16 binding protein 5 (sprot)

A UL-16 binding protein 5 that is encoded in the genome of human.


PLET1_HUMAN Placenta-expressed transcript 1 protein (sprot)

A placenta-expressed transcript 1 protein that is encoded in the genome of human.


LYPD4_HUMAN Ly6/PLAUR domain-containing protein 4 (sprot)

An Ly6/PLAUR domain-containing protein 4 that is encoded in the genome of human.


LYPD5_HUMAN Ly6/PLAUR domain-containing protein 5 (sprot)

An Ly6/PLAUR domain-containing protein 5 that is encoded in the genome of human.


LYPD8_HUMAN Ly6/PLAUR domain-containing protein 8 (sprot)

An Ly6/PLAUR domain-containing protein 8 that is encoded in the genome of human.


LYPD2_HUMAN Ly6/PLAUR domain-containing protein 2 (sprot)

An Ly6/PLAUR domain-containing protein 2 that is encoded in the genome of human.


OTOAN_HUMAN Otoancorin (sprot)

An otoancorin that is encoded in the genome of human.


PRS41_HUMAN Serine protease 41 (sprot)

A testis serine protease 1 that is encoded in the genome of human.


MDGA2_HUMAN MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (sprot)

A MAM domain-containing glycosylphosphatidylinositol anchor protein 2 that is encoded in the genome of human.


R4RL1_HUMAN Reticulon-4 receptor-like 1 (sprot)

A reticulon-4 receptor-like 1 that is encoded in the genome of human.


R4RL2_HUMAN Reticulon-4 receptor-like 2 (sprot)

A reticulon-4 receptor-like 2 that is encoded in the genome of human.


CNTN4_HUMAN Contactin-4 (sprot)

A contactin-4 that is encoded in the genome of human.


LYPD1_HUMAN Ly6/PLAUR domain-containing protein 1 (sprot)

An Ly6/PLAUR domain-containing protein 1 that is encoded in the genome of human.


LPD6B_HUMAN Ly6/PLAUR domain-containing protein 6B (sprot)

An Ly6/PLAUR domain-containing protein 6B that is encoded in the genome of human.


SACA4_HUMAN Sperm acrosome membrane-associated protein 4 (sprot)

A sperm acrosome membrane-associated protein 4 that is encoded in the genome of human.


NAR4_HUMAN Ecto-ADP-ribosyltransferase 4 (sprot)

An ecto-ADP-ribosyltransferase 4 that is encoded in the genome of human.


NTNG2_HUMAN Netrin-G2 (sprot)

A netrin-G2 that is encoded in the genome of human.


TECTB_HUMAN Beta-tectorin (sprot)

A beta-tectorin that is encoded in the genome of human.


TX101_HUMAN Testis-expressed protein 101 (sprot)

A testis-expressed protein 101 that is encoded in the genome of human.


ULBP2_HUMAN UL16-binding protein 2 (sprot)

A UL16-binding protein 2 that is encoded in the genome of human.


NRN1_HUMAN Neuritin (sprot)

A neuritin that is encoded in the genome of human.


NTRI_HUMAN Neurotrimin (sprot)

A neurotrimin that is encoded in the genome of human.


CNTN3_HUMAN Contactin-3 (sprot)

A contactin-3 that is encoded in the genome of human.


PRND_HUMAN Prion-like protein doppel (sprot)

A prion-like protein doppel that is encoded in the genome of human.


NTNG1_HUMAN Netrin-G1 (sprot)

A netrin-G1 that is encoded in the genome of human.


TEST_HUMAN Testisin (sprot)

A testisin that is encoded in the genome of human.


Homolanthionine

A sulfur-containing amino acid in which the gamma-carbon atoms of two molecules of L-aminobutyric acid are joined via a thioether linkage. It is a byproduct of cystathionine-gamma-lyase and a possible human hyperhomocysteinemia marker.


Serine

The L-enantiomer of serine.


P3C2A_HUMAN Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (sprot)

A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha that is encoded in the genome of human.


NAD(+) hydrolase SARM1 isoform 1 (human)

An NAD(+) hydrolase SARM1 isoform 1 that is encoded in the genome of human.


TLR10_HUMAN Toll-like receptor 10 (sprot)

A Toll-like receptor 10 that is encoded in the genome of human.


NGF_HUMAN Beta-nerve growth factor (sprot)

A beta-nerve growth factor that is encoded in the genome of human.


S1PR3_HUMAN Sphingosine 1-phosphate receptor 3 (sprot)

A sphingosine 1-phosphate receptor 3 that is encoded in the genome of human.


The gamma-D-glutamyl derivative of meso-diaminopimelic acid. Minimal ligand of NOD1.


CTF18_HUMAN Chromosome transmission fidelity protein 18 homolog (sprot)

A chromosome transmission fidelity protein 18 that is encoded in the genome of human.


RFC2_HUMAN Replication factor C subunit 2 (sprot)

A replication factor C subunit 2 that is encoded in the genome of human.


RFC4_HUMAN Replication factor C subunit 4 (sprot)

A replication factor C subunit 4 that is encoded in the genome of human.


RFC3_HUMAN Replication factor C subunit 3 (sprot)

A replication factor C subunit 3 that is encoded in the genome of human.


RFC5_HUMAN Replication factor C subunit 5 (sprot)

A replication factor C subunit 5 that is encoded in the genome of human.


DCC1_HUMAN Sister chromatid cohesion protein DCC1 (sprot)

A sister chromatid cohesion protein DCC1 that is encoded in the genome of human.


CTF8_HUMAN Chromosome transmission fidelity protein 8 homolog (sprot)

A chromosome transmission fidelity protein 8 homolog that is encoded in the genome of human.


CTC1_HUMAN CST complex subunit CTC1 (sprot)

A CST complex subunit CTC1 that is encoded in the genome of human.


STN1_HUMAN CST complex subunit STN1 (sprot)

An oligonucleotide/oligosaccharide-binding fold-containing protein 1 that is encoded in the genome of human.


TEN1L_HUMAN CST complex subunit TEN1 (sprot)

A CST complex subunit TEN1 that is encoded in the genome of human.


Foscarnet

Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.


Mandelic Acid

A 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups.


Amylopectin

A polydisperse highly branched polysaccharide derivative composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage. The chains are joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some 6-phosphate ester groups also may occur. The branches in amylopectin typically contain 24 to 30 glucose residues.


An oxoicosatetraenoic acid that is (5Z,8Z,12E,14Z)-icosatetraenoic acid bearing a single oxo substituent located at position 12.


An imidazobenzodiazepine that is midazolam which is substituted by a hydroxy group at position 4. It is the minor hydroxylated metabolite of the anesthetic, midazolam.


Enalaprilat dihydrate

The dihydrate form of enalaprilat, an angiotensin-converting enzyme (ACE) inhibitor that is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is administered by intravenous injection.


Sodium Iodide

A metal iodide salt with a Na(+) counterion.


Rivaroxaban

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-chlorothiophene-2-carboxylic acid with the amino group of 4-{4-[(5S)-5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one. An anticoagulant used for prophylaxis of venous thromboembolism in patients with knee or hip replacement surgery.


Ganglioside GM1

A sialotetraosylceramide consisting of a branched pentasaccharide made up from one sialyl residue, two galactose residues, one N-acetylgalactosamine residue and a glucose residue at the reducing end attached to N-stearoylsphingosine via a beta-linkage.


An 8,9-EET in which the epoxy moiety has 8S,9R-configuration.


Leucine enkephalin

A pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties.


Glycerophosphoric acid

A glycerol monophosphate having the phosphate group located at position 1.


Mepiquat

A quaternary ammonium ion has that has two methyl groups and a pentamethylene-1,5-diyl group attached to the nitrogen. Its salts are used as plant growth inhibitors.


glucosylceramide

Any of the cerebrosides in which the monosaccharide head group is glucose.


A trienoic fatty acid that consists of heptadeca-5,8,10-trienoic acid bearing an additional 12-hydroxy substituent.


Guanosine substituted at the purine 8-position by a hydroxy group. It is used as a biomarker of oxidative DNA damage.


Valdecoxib

A member of the class of isoxazoles that is isoxazole which is substituted at positions 3, 4 and 5 by phenyl, p-sulfamoylphenyl and methyl groups, respectively. A selective cyclooxygenase 2-inhibitor, it used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of arthritis from 2001 until 2005, when it was withdrawn following concerns of an associated increased risk of heart attack and stroke.


Finasteride

An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.


Tolnaftate

A monothiocarbamic ester that is the methyl(3-tolyl)carbamothioate ester of 2-naphthol. A synthetic anti-fungal agent used to treat jock itch, athlete's foot and ringworm.


Azoxystrobin

An aryloxypyrimidine having a 4,6-diphenoxypyrimidine  skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture.


Orphenadrine

A tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol.


Egtazic acid

A  diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.


4-Phenylbutyric acid

A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4.  It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.


polysaccharide

A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues.


Icariin

A member of the class of flavonols that is kaempferol which is substituted at position 8 by a 3-methylbut-2-en-1-yl group and in which the hydroxy groups at positions 3, 4', and 7 have been converted to the corresponding 6-deoxy-alpha-L-mannopyranoside, methyl ether, and beta-D-glucopyranoside, respectively. A phoshphodiesterase-5 inhibitor, it is obtained from several species of plants in the genus Epimedium and is thought to be the main active ingredient of the Chinese herbal medicine Herba Epimedii (yinyanghuo).


Amphotericin B

A macrolide antibiotic used to treat potentially life-threatening fungal infections.


Secobarbital

A member of the class of  barbiturates that is barbituric acid in which the hydrogens at position 5 are substituted by prop-2-en-1-yl and pentan-2-yl groups.


An N-sulfonyldiazepane resullting from the formal condensation of 5-iodo-1-naphthylsulfonic acid with one of the nitrogens of 1,4-diazepane. It is a selective inhibitor of myosin light chain kinase (EC 2.7.11.18).


A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively.


Dexfenfluramine

The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.


Glycyrrhizin

A  triterpenoid saponin that is the  glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.


Hydroxychloroquine

An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.


Troleandomycin

A semi-synthetic macrolide antibiotic obtained by acetylation of the three free hydroxy groups of oleandomycin. Troleandomycin is only found in individuals that have taken the drug.


Quinapril

A member of the class of isoquinolines that is (3S)-2-L-alanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid in which the alpha-amino group of the alanyl residue has been substituted by a 1-ethoxycarbonyl-4-phenylbutan-2-yl group (the all-S isomer). A prodrug for quinaprilat (by hydrolysis of the ethyl ester to the corresponding carboxylic acid), it is used as an angiotensin-converting enzyme inhibitor (ACE inhibitor) used (generally as the hydrochloride salt) for the treatment of hypertension and congestive heart failure.


Trigonelline

An iminium betaine that is the conjugate base of N-methylnicotinic acid, arising from deprotonation of the carboxy group.


TROPISETRON

An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.


Amitraz

A tertiary amino compound that is 1,3,5-triazapenta-1,4-diene substituted by a methyl group at position 3 and 2,4-dimethylphenyl groups at positions 1 and 5.


Sesquiterpenes

A C15 terpene.


enzyme inhibitor

A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.


Ethionamide

A thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2. A prodrug that undergoes metabolic activation by conversion to the corresponding S-oxide.


A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-hydroxyphenyl, pyridin-4-yl, and 4-fluorophenyl groups, respectively. It is a widely used inhibitor of mitogen-activated protein kinase (MAPK) alpha and beta.


Oxybuprocaine

A benzoate ester in which 4-amino-3-butoxybenzoic acid and 2-(diethylamino)ethanol have combined to form the ester bond; an ester-based local anaesthetic (ester "caine") used especially in ophthalmology and otolaryngology.


Fenbendazole

A member of the class of benzimidazoles that is 1H-benzimidazole  which is substituted at positons 2 and 5 by (methoxycarbonyl)amino and phenylsulfanediyl groups, respectively. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.


Carbendazim

A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls  Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables.


A salicylanilide derivative with chloride substituents at C-3 and C-5 of the salicylate moiety and at C-3 and C-4 of the anilide moiety.


Nisoldipine

A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.


Nimodipine

A dihydropyridine that is 1,4-dihydropyridine which is substituted by methyl groups at positions 2 and 6, a (2-methoxyethoxy)carbonyl group at position 3, a m-nitrophenyl group at position 4, and an isopropoxycarbonyl group at position 5. An L-type calcium channel blocker, it acts particularly on cerebral circulation, and is used both orally and intravenously for the prevention and treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm.


Rolipram

A member of the lclass of pyrrolidin-2-ones that is pyrrolidin-2-one bearing a 3-(cyclopentyloxy)-4-methoxyphenyl substituent at the 4-position.  It is a type IV-specific phosphodiesterase (PDE4) inhibitor.


Metyrapone

An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.


Ramipril

A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.


Sodium perchlorate

An inorganic sodium salt comprising equal numbers of sodium and perchlorate ions.


Indapamide

A sulfonamide formed by condensation of the carboxylic group of 4-chloro-3-sulfamoylbenzoic acid with the amino group of 2-methyl-2,3-dihydro-1H-indol-1-amine.


Epalrestat

A monocarboxylic acid that is 1,3-thiazolidine which is substituted on the nitrogen by a carboxymethyl group, at positions 2 and 4 by thioxo and oxo groups, respectively, and at position 5 by a 2-methyl-3-phenylprop-2-en-1-ylidene group. It is an inhibitor of aldose reductase (which catalyses the conversion of glucose to sorbitol) and is used for the treatment of some diabetic complications, including neuropathy.


Vanillic Acid

A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3.


A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.


Tyrphostin B42

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid with the amino group of benzylamine.


Anisomycin

An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.


Anthralin

An anthracene compound derived by the substitution of -OH groups for hydrogen at C-1 and C-8, and with an oxo group at C-9.


Isoquercitrin

A quercetin O-glucoside in which a glucofuranosyl residue is attached at position 3 of quercetin via a beta-glycosidic linkage.


Epsilon-viniferin

A stilbenoid that is the (-)-trans-stereoisomer of epsilon-viniferin, obtained by cyclodimerisation of trans-resveratrol.


Glutaric acid

An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.


Propamocarb

A carbamate ester that is the propyl ester of 3-(dimethylamino)propylcarbamic acid. It is a systemic fungicide, used (normally as the hydrochloride salt) for the control of soil, root and leaf diseases caused by oomycetes, particularly  Phytophthora and Pythium species.


Methoctramine free base

A tetramine that is N,N'-bis(6-aminohexyl)octane-1,8-diamine where the primary amino groups both carry 2-methoxybenzyl substituents.


Anastrozole

A 1,2,4-triazole compound having a 3,5-bis(2-cyano-2-propyl)benzyl group at the 1-position.


Dexamethasone phosphate

A steroid phosphate that is the 21-O-phospho derivative of dexamethasone.


Embelin

A member of the class of dihydroxy-1,4-benzoquinones that is 2,5-dihydroxy-1,4-benzoquinone which is substituted by an undecyl group at position 3. Isolated from Lysimachia punctata and Embelia ribes, it exhibits antimicrobial, antineoplastic and inhibitory activity towards hepatitis C protease.


Jasplakinolide

A cyclodepsipeptide isolated from Jaspis splendens and has been shown to exhibit antineoplastic activity. It is an actin polymerization and stabilization inducer.


Baicalin

The glycosyloxyflavone which is the 7-O-glucuronide of baicalein. It is an active ingredient of Chinese herbal medicine Scutellaria baicalensis.


Merbromina

An organic sodium salt that is 2,7-dibromo-4-hydroxymercurifluorescein in which the carboxy group and the phenolic hydroxy group have been deprotonated and the resulting charge is neutralised by two sodium ions.


A monohydroxyflavone that is the 3-hydroxy derivative of flavone.


Parnate

A 2-phenylcyclopropan-1-amine that is the (1R,2S)-enantiomer of tranylcypromine.


Thiostrepton

A heterodetic cyclic peptide, in which the cyclisation step involves a formal lactonisation between the carboxy group of a quinaldic acid-based residue and a secondary alcohol. An antibiotic that inhibits bacterial protein synthesis. Also acts as an antitumor agent.


Seliciclib

2,6-Diaminopurine carrying benzylamino, (2R)-1-hydroxybutan-2-yl and isopropyl substituents at C-6, C-2-N and N-9 respectively. It is an experimental drug candidate in the family of pharmacological cyclin-dependent kinase (CDK) inhibitors.


Pentamidine

A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A  trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.


A quinazoline alkaloid that is a marine toxin isolated from fish such as puffer fish. It has been shown to exhibit potential neutotoxicity due to its ability to block voltage-gated sodium channels.


Cromolyn sodium

An organic sodium salt that is the disodium salt of cromoglycic acid.


Procyclidine

A tertiary alcohol that consists of propan-1-ol substituted by a cyclohexyl and a phenyl group at position 1 and a pyrrolidin-1-yl group at position 3.


ganglioside

A molecule composed of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acids linked on the sugar chain.


Chlormequat

A quaternary ammonium ion that is choline in which the hydroxy group has been replaced by a chlorine. Its salts (particularly the chloride salt, known as chlormequat chloride) are used as plant growth retardants.


Droperidol

An organofluorine compound that is haloperidol in which the hydroxy group has been eliminated with the introduction of a double bond in the piperidine ring, and the 4-chlorophenyl group has been replaced by a benzimidazol-2-on-1-yl group. It is used in the management of chemotherapy-induced nausea and vomiting, and in conjunction with an opioid analgesic such as fentanyl to maintain the patient in a calm state of neuroleptanalgesia with indifference to surroundings but still able to cooperate with the surgeon.


Edaravone

A pyrazolone that is 2,4-dihydro-3H-pyrazol-3-one which is substituted at positions 2 and 5 by phenyl and methyl groups, respectively.


Idebenone

A member of the class of 1,4-benzoquinones which is substituted by methoxy groups at positions 2 and 3, by a methyl group at positions 5, and by a 10-hydroxydecyl group at positions 6. Initially developed for the treatment of Alzheimer's disease, benefits were modest; it was subsequently found to be of benefit for the symptomatic treatment of Friedreich's ataxia.


Phenylbutazone

A member of the class of  pyrazolidines that is 1,2-diphenylpyrazolidine-3,5-dione carrying a butyl group at the 4-position.


Pergolide

A diamine that is ergoline in which the beta-hydrogen at position 8 is replaced by a (methylthio)methyl group and the hydrogen attached to the piperidine nitrogen (position 6) is replaced by a propyl group. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used as the mesylate salt in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction.


5,5-Dimethyl-1-pyrroline N-oxide

A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.


Zonalon

A dibenzooxepine that is 6,11-dihydrodibenzo[b,e]oxepine substituted by a 3-(dimethylamino)propylidene group at position 11. It is used as an  antidepressant drug.


Rimsulfuron

A  N-sulfonylurea that is N-carbamoyl-3-(ethylsulfonyl)pyridine-2-sulfonamide substituted by a 4,6-dimethoxypyrimidin-2-yl group at the amino nitrogen atom.


A biflavonoid that is 3,4,5-trihydroxybenzocyclohepten-6-one which is substituted at positions 1 and 8 by (2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl groups. It is the main red pigment in black tea.


Desoximetasone

Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis.


Acetyl-L-carnitine

An O-acyl-L-carnitine where the acyl group specified is acetyl. It facilitates movement of acetyl-CoA into the matrices of mammalian mitochondria during the oxidation of fatty acids.


Exemestane

A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer.


BUTYLSCOPOLAMINE BROMIDE

An organic bromide salt of butylscopolamine. It is an antispasmodic drug which can relieve painful stomach cramps (including those linked with irritable bowel syndrome), bladder and menstrual cramps.


omega Conopeptide gvia (conus)

A heterodetic cyclic polypeptide consisting of the linear sequence Cys-Lys-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2 with three disulfide bridges between cysteine residues 1-16, 8-19 and 15-26. Isolated from the venom of the fish-hunting snail Conus geographus.


Chlorantraniliprole

A carboxamide resulting from the formal condensation of the carboxylic acid group of 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxylic acid with the primary amino group of 2-amino-5-chloro-N,3-dimethylbenzamide. The first of the anthranilic diamide insecticides, it is a ryanodine receptor activator and is used to protect a wide variety of crops, including corn, cotton, grapes, rice and potatoes.


Cephalothin

A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections.


Digitonin

A spirostanyl glycoside that is digitogenin in which the 3-hydroxy group is substituted by a beta-D-glucopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->2)-[beta-D-xylopyranosyl-(1->3)]-beta-D-glucopyranosyl-(1->4)-beta-D-galactopyranosyl group. It is a steroidal saponin isolated from the foxglove plant, Digitalis purpurea. It is used extensively as a mild non-ionic detergent for extracting proteins from membranes for structure and function studies.


A pentasubstituted dihydropyridine carrying methoxycarbonyl, 2-(trifluoromethyl)phenyl and nitro substituents at positions 3, 4 and 5 respectively as well as two methyl substituents at positions 2 and 6.


A 3-oxo-5alpha- steroid that is 4,5alpha-dihydrotestosterone which is substituted by a hydroxymethylidene group at position 2 and by a methyl group at the 17alpha position. A synthetic androgen, it was mainly used for the treatment of anaemias until being replaced by treatments with fewer side effects.


Cinnamyl alcohol

The E (trans) stereoisomer of cinnamyl alcohol.


Ergotamine

A peptide ergot alkaloid that is dihydroergotamine in which a double bond replaces the single bond between positions 9 and 10.


Megestrol acetate

A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer.


Benzoic acid, 4-((1E)-3-((2-ethoxy-2-oxoethyl)-2-propenylamino)-2-methyl-3-oxo-1-propenyl)-, 4-(aminoiminomethyl)phenyl ester, monomethanesulfonate


Hydroxyzine

A N-alkylpiperazine that is piperzine in which the nitrogens atoms are substituted by 2-(2-hydroxyethoxy)ethyl and (4-chlorophenyl)(phenyl)methyl groups respectively.


Ketotifen

An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.


Tubocurarine chloride

A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare.


Calpain Inhibitor III

A dipeptide resulting from the formal condensation of the carboxy group of N-benzyloxycarbonyl-L-valine with the amino group of L-phenylalanine aldehyde. It is a potent cell-permeable inhibitor of calpain I and II, and is also a gamma-secretase inhibitor.


Methyl pyruvate

A pyruvate ester resultinf grom the formal condensation of the carboxy group of pyruvic acid with the hydroxy group of methanol.


S-Methyl methanethiosulfonate

A sulfonic acid derivative obtained by condensaton of methanesulfonic acid with methanethiol.


Neflamapimod

A member of the class of pyrimidopyridazines that is 6H-pyrimido[1,6-b]pyridazin-6-one substituted at positions 2 and 5 by (2,4-difluorophenyl)sulfanyl and 2,6-dichlorophenyl groups respectively


Formestane

A 17-oxo steroid that is androst-4-ene-3,17-dione in which the hydrogen at position 4 is replaced by a hydroxy group. Formestane was the first selective, type I steroidal aromatase inhibitor, suppressing oestrogen production from anabolic steroids or prohormones. It was formerly used in the treatment of oestrogen-receptor positive breast cancer in post-meopausal women. As it has poor oral bioavailability, it had to be administered by (fortnightly) intramuscular injection. It fell out of use with the subsequent development of cheaper, orally active aromatase inhibitors. Formestane is listed by the World Anti-Doping Agency as a substance prohibited from use by athletes.


Prinomastat

A hydroxamic acid that is (3S)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide in which the hydrogen attached to the thiomorpholine nitrogen has been replaced by a [4-(pyridin-4-yloxy)phenyl]sulfonyl group. It is a selective inhibitor with of matrix metalloproteinases (MMPs) 2, 3, 9, 13, and 14.


cis-9, trans-11-conjugated linoleic acid


Leuprorelin

An oligopeptide comprising pyroglutamyl, histidyl, tryptophyl, seryl, tyrosyl, D-leucyl, leucyl, arginyl, and N-ethylprolinamide residues joined in sequence. It is a synthetic nonapeptide analogue of gonadotropin-releasing hormone, and is used as a subcutaneous hydrogel implant (particularly as the acetate salt) for the treatment of prostate cancer and for the suppression of gonadal sex hormone production in children with central precocious puberty.


SKF-96365 free base

An ether that is 2-(1H-imidazol-1-yl)-1-(4-methoxyphenyl)ethanol in which the hydrogen of the hydroxy group has been substituted by a 3-(4-methoxyphenyl)propyl group.


1H-Benzimidazole-4-propanoic acid, beta-hydroxy-2-(2-phenylethyl)-, ethyl ester


C.I. Basic Red 9

An imine that is 4-methylidenecyclohexa-2,5-dien-1-imine in which both the hydrogens of the methylidene group are replaced by 4-aminophenyl groups. The hydrochloride salt is the histological dye 'pararosaniline'.


Chlorphenesin carbamate

The carbamate ester of the primary hydroxy group of chlorphenesin. A centrally acting skeletal muscle relaxant, it is used in the symptomatic treatment of painful muscle spasm.


Dequalinium

A quinolinium ion comprising decane in which one methyl hydrogen at each end of the molecule has been replaced by a 4-amino-2-methylquinolin-1-yl group.


Dithioerythritol

The meso-diastereomer of 1,4-dimercaptobutane-2,3-diol; a sulfur-containing sugar derived from the monosaccharide erythrose; and an epimer of dithiothreitol.


Ciclopirox

A cyclic hydroxamic acid that is 1-hydroxypyridin-2(1H)-one in which the hydrogens at positions 4 and 6 are substituted by methyl and cyclohexyl groups, respectively. A broad spectrum antigfungal agent, it also exhibits antibacterial activity against many Gram-positive and Gram-negative bacteria, and has anti-inflammatory properties. It is used a a topical treatment of fungal skin and nail infections.


Fluorometholone

A member of the class of glucocorticoids that is Delta(1)-progesterone substituted at positions 11beta and 17 by hydroxy groups, at position 6alpha by a methyl group and at position 9 by a fluoro group. Used for the treatment of corticosteroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.


furans

Compounds containing at least one furan ring.


Oxyphenbutazone hydrate

A hydrate obtained by combining oxyphenbutazone with one molar equivalent of water. Commonly used to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.


Bopindolol

A methylindole that is 2-methyl-1H-indol-4-ol in which the hydrogen of the hydroxy group is replaced by a 2-(benzoyloxy)-3-(tert-butylamino)propyl group.


Cefoperazone

A semi-synthetic parenteral cephalosporin with a tetrazolyl moiety that confers beta-lactamase resistance.


Mevastatin

A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals.


A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.


Raffinose

A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively.


Acetonitrile

A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group.


Eupatilin

A trimethoxyflavone that is flavone substituted by hydroxy groups at C-5 and C-7 and methoxy groups at C-6, C-3' and C-4' respectively. Isolated from Citrus reticulata and Salvia tomentosa, it exhibits anti-inflammatory, anti-ulcer and antineoplastic activities.


Trandolapril

A heterobicylic compound that is (2S,3aR,7aS)-1-[(2S)-2-aminopropanoyl]octahydro-1H-indole-2-carboxylic acid in which the hydrogen of the amino group is substituted by a (2R)-1-ethoxy-1-oxo-4-phenylbutan-2-yl group. It is a angiotensin-converting enzyme inhibitor and a prodrug used for the treatment of hypertension.


Cytisinicline

An organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking.


Pyrazine

A diazine that is benzene in which the carbon atoms at positions 1 and 4 have been replaced by nitrogen atoms.


A tertiary phosphine in which phosphane is substituted with three 2-carboxyethyl groups. It is a commonly used reducing agent.


Bromhexine

A substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum).


Nandrolone

A 3-oxo Delta(4)-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17.


Sodium thiocyanate

An organic sodium salt which is the monosodium salt of thiocyanic acid.


Dithianon

A naphthodithiin that is 5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiin which is substituted by nitrile groups at positions 2 and 3. It is a broad spectrum fungicide used to control scab, downy mildew, rust, and leaf spot in the commercial growing of grapes and other fruit, citrus, coffee, and vegetables.


Diflufenican

A pyridinecarboxamide that is pyridine-3-carboxamide substituted by a 2,4-difluorophenyl group at the carbamoyl nitrogen and a 3-(trifluoromethyl)phenoxy group at position 2.


Sertindole

A phenylindole that is 1H-indole which is substituted on the nitrogen by a p-chlorophenyl group, at position 5 by chlorine, and at position 3 by a piperidin-4-yl group, which is itself substituted on the nitrogen by a 2-(2-oxoimidazolidin-1-yl)ethyl group.


A fatty acid derivative that is arachidonic acid in which the OH part of the carboxy group has been replaced by a trifluoromethyl group


Isobutanol

An alkyl alcohol that is propan-1-ol substituted by a methyl group at position 2.


Ajmalicine

A monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure.


Promazine

A phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position.


A member of the class of benzaldehydes carrying a diethylamino substituent at position 4.


Brompheniramine

Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.


Rifamycin

A member of the class of rifamycins that exhibits antibiotic and antitubercular properties.


A secondary alcohol that is butane substituted by a hydroxy group at position 2.


Chlorhexidine

A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge.


tert-Butanol

A tertiary alcohol alcohol that is isobutane substituted by a hydroxy group at position 2.


An organic phosphonate that is the trisacetoxymethylester derivative of naphthalene substituted  hydroxymethylphosphonic acid. It has been found to inhibit insulin receptor tyrosine kinase activity and insulin stimulated glucose oxidation.


A member of the class of isoquinolines that is the sulfonamide formed by the formal condensation of the sulfo group of 4-methylisoquinoline-5-sulfonic acid with the 1-amino group of (S)-2-methyl-1,4-diazepane.


N-Oleoyldopamine

A fatty amide resulting from the formal condensation of the carboxy group of oleic acid with the amino group of dopamine. Synthesised in catecholaminergic neurons, it crosses the blood-brain barrier and might be considered as a carrier of dopamine into the brain. It is a  transient receptor potential vanilloid type 1 (TRPV1) receptor agonist.


Clofazimine

3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of  multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients.


An alkyl alcohol that is pentane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It has been isolated from Melicope ptelefolia.


Bretylium tosylate

The tosylate salt of bretylium.  It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.


Cyclobenzaprine

5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.


Diphenidol

A tertiary alcohol that is butan-1-ol substituted by two phenyl groups at position 1 and a piperidin-1-yl group at position 4.


Cefazolin

A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively.


Edelfosine

A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.


Astressin

A 30-membered homodetic cyclic peptide comprising the sequence D-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Nle-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Glu-Ala-His-Lys-Asn-Arg-Lys-Leu-Nle-Glu-Ile-Ile-NH2 cyclised by an amide bridge, formed by condensation of the side-chain carboxy group of the Glu residue at position 19 and the side-chain amino group of the Lys residue at position 22.


Clorprenaline

A racemate comprise of equimolar amounts of (R)- and (S)-clorprenaline. It is a beta2-adrenergic receptor agonist and a bronchodilator.


Terconazole

A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have R and S configuration, respectively.


Azosemide

A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hypertension.


Beryllium fluoride

The fluoride salt of beryllium (+2 oxidation state). In the solid state it exists as a glass, with four-coordinate Be(2+) tetrahedral centres and two-coordinate fluoride centres. As a gas it adopts a linear triatomic structure and in the liquid state a fluctuating tetrahedral structure. In protein crystallography it is used as a mimic of phosphate.


Quinaprilat

A dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril.


Acetophenone

A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.


Dexbrompheniramine

The (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.


An alpha-bromoketone that is acetophenone substituted by a bromo group at position 2.


A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.


Bithionol

An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.


Iodoquinol

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine.  It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis.


Octanoylcarnitine

An O-acylcarnitine having octanoyl as the acyl substituent.


ATOVAQUONE

A naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position.


Chlorprothixene

A chlorprothixene in which the double bond adopts a (Z)-configuration.


Lornoxicam

A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations.


(1-((2-Methoxy-4-(((phenylsulfonyl)amino)carbonyl)phenyl)methyl)-1H-indazol-6-yl)carbamic acid cyclopentyl ester


The class of beta-lactam antibiotics that whose members have a carbapenem skeleton which is variously substituted at positions 3, 4, and 6.


Diethyl pyrocarbonate

The diethyl ester of dicarbonic acid.


Dyclonine

N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.


A phytocannabinoid that is Delta(9)-tetrahydrocannabinol in which the C-11 methyl has been fully oxidised to a carboxy group. Further enzymatic oxidation product of 11-hydroxy-Delta(9)-tetrahydrocannabinol.


Flumazenil

An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.


Betamethasone dipropionate

A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.


Guanidine carrying a phenyl substituent on each of the two amino groups. It is used as an accelerator in the rubber industry.


Eperisone

A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.


Serpentine (alkaloid)

An indole alkaloid that is 18-oxayohimban dehydrogenated at positions 3, 4, 5, 6, 16 and 17 and substituted by a methyl group at the 19alpha position and by a methoxycarbonyl group at position 16.


HYOSCYAMINE

An atropine with a 2S-configuration.


The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.


Sodium Bromide

An inorganic sodium salt having bromide as the counterion.


Antazoline

A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.


Cardenolide

A steroid lactone that is a C23 steroid with methyl groups at C-10 and C-13 and a butenolide ring at C-17.


Dicyclomine

The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.


flavin

A derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.


Amperozide

A member of the class of ureas that is urea in which three of the four hydrogens are replaced by ethyl and 4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl groups. An atypical antipsychotic which was in clinical development for the treatment of schizophrenia and substance-related disorders. It is a potent 5-HT2A antagonist and used in veterinary medicine because of its sedative effect on pigs.


cyclic ADP-ribose

A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.


Lysergol

An alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi and in the morning glory family of plants. Its structure is that of ergoline with a methyl group at N-6 and a beta-hydroxymethyl substituent at C-8.


Adipic Acid

An alpha,omega-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.


Monepantel

A secondary carboxamide resulting from the formal condensation of the carboxy group of p-[(trifluoromethyl)sulfanyl]benzoic acid with the amino group of (2S)-2-amino-3-hydroxy-2-methylpropanenitrile in which the hydroxy group has been converted to the corresponding 5-cyano-2-(trifluoromethyl)phenyl ether. A broad-spectrum nematicide, it is used to control gastrointestinal roundworms in sheep and goats.


Phenothiazine

The 10H-tautomer of phenothiazine.


Pridinol

A piperidine substituted at position 1 by a 3-hydroxy-3,3-diphenylpropyl group.


Cefonicid

A cephalosporin bearing {[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and (R)-2-hydroxy-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton.


Adrenosterone

A 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17.


Carbinoxamine

An organochlorine compound that is 2-(4-chlorobenzyl)pyridine in which one of the benzylic hydrogens is substituted by 2-(dimethylamino)ethoxy group. It is an ethanolamine-type antihistamine, used as its maleate salt for treating hay fever, as well as mild cases of Parkinson's disease.


Trimipramine

A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.


Mosapride

A benzamide resulting from the formal condensation of the carboxy group of 4-amino-5-chloro-2-ethoxybenzoic acid with the amino group of 1-[4-(4-fluorobenzyl)morpholin-2-yl]methanamine.


(+)-Himbacine

A  piperidine alkaloid that is decahydronaphtho[2,3-c]furan-1(3H)-one substituted by a methyl group at position 3 and a 2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl group at position 4. It has been isolated from the bark of Australian magnolias.


Perfluorodecalin

A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.


Eliprodil

A member of the class of piperidines that is piperidine substituted by a 2-(4-chlorophenyl)-2-hydroxyethyl group at position 1 and by a 4-fluorobenzyl group at position 4.


Bapta

A polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene.


Phosphomethylphosphonic acid adenylate ester


A  glycosyloxyflavone that is  luteolin substituted by a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage. It has been isolated from Olea europaea.


Sodium chromate

An inorganic sodium salt consisting of sodium and chromate ions in a 2:1 ratio.


Rulide

A major geometrical isomer of roxithromycin.


aromatase activity

Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.


aromatase

A protein that is a translation product of the human CYP19A1 gene or a 1:1 ortholog thereof.


Phthalimide substituted at the 4- and 5-positions by anilino groups.


Alclofenac

An aromatic ether in which the ether oxygen links an allyl group to the 4-position of (3-chlorophenyl)acetic acid.A non-steroidal anti-inflammatory drug, it was withdrawn from the UK market in 1979 due to concerns with its association with vasculitis and rash.


Meclofenamic acid

An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.


Tiaprofenic acid

An aromatic ketone that is thiophene substituted at C-2 by benzoyl and at C-4 by a 1-carboxyethyl group.


Leucovorin

A formyltetrahydrofolic acid in which the formyl group is located at position 5.


Nicotinic acid riboside

Conjugate base of D-ribosylnicotinic acid.


EPN4_HUMAN Clathrin interactor 1 (sprot)

A clathrin interactor 1 that is encoded in the genome of human.


SH319_HUMAN SH3 domain-containing protein 19 (sprot)

An SH3 domain-containing protein 19 that is encoded in the genome of human.


PUM1_HUMAN Pumilio homolog 1 (sprot)

A pumilio homolog 1 that is encoded in the genome of human.


DTBP1_HUMAN Dysbindin (sprot)

A dysbindin that is encoded in the genome of human.


BL1S4_HUMAN Biogenesis of lysosome-related organelles complex 1 subunit 4 (sprot)

A biogenesis of lysosome-related organelles complex 1 subunit 4 that is encoded in the genome of human.


A deoxyribonuclease-2-alpha that is encoded in the genome of human.


AP3B1_HUMAN AP-3 complex subunit beta-1 (sprot)

An AP-3 complex subunit beta-1 that is encoded in the genome of human.


SNX2_HUMAN Sorting nexin-2 (sprot)

A sorting nexin-2 that is encoded in the genome of human.


HIP1R_HUMAN Huntingtin-interacting protein 1-related protein (sprot)

A huntingtin-interacting protein 1-related protein that is encoded in the genome of human.


CBPD_HUMAN Carboxypeptidase D (sprot)

A carboxypeptidase D that is encoded in the genome of human.


SNAPN_HUMAN SNARE-associated protein Snapin (sprot)

A SNARE-associated protein Snapin that is encoded in the genome of human.


MPRD_HUMAN Cation-dependent mannose-6-phosphate receptor (sprot)

A cation-dependent mannose-6-phosphate receptor that is encoded in the genome of human.


TPD52_HUMAN Tumor protein D52 (sprot)

A tumor protein D52 that is encoded in the genome of human.


TBC8B_HUMAN TBC1 domain family member 8B (sprot)

A TBC1 domain family member 8B that is encoded in the genome of human.


PICAL_HUMAN Phosphatidylinositol-binding clathrin assembly protein (sprot)

A phosphatidylinositol-binding clathrin assembly protein that is encoded in the genome of human.


TPD53_HUMAN Tumor protein D53 (sprot)

A tumor protein D53 that is encoded in the genome of human.


AP3S1_HUMAN AP-3 complex subunit sigma-1 (sprot)

An AP-3 complex subunit sigma-1 that is encoded in the genome of human.


YIPF6_HUMAN Protein YIPF6 (sprot)

A protein YIPF6 that is encoded in the genome of human.


SORT_HUMAN Sortilin (sprot)

A sortilin that is encoded in the genome of human.


AP4E1_HUMAN AP-4 complex subunit epsilon-1 (sprot)

An AP-4 complex subunit epsilon-1 that is encoded in the genome of human.


SNX5_HUMAN Sorting nexin-5 (sprot)

A sorting nexin-5 that is encoded in the genome of human.


AP4B1_HUMAN AP-4 complex subunit beta-1 (sprot)

An AP-4 complex subunit beta-1 that is encoded in the genome of human.


THRSP_HUMAN Thyroid hormone-inducible hepatic protein (sprot)

A thyroid hormone-inducible hepatic protein that is encoded in the genome of human.


M1IP1_HUMAN Mid1-interacting protein 1 (sprot)

A Mid1-interacting protein 1 that is encoded in the genome of human.


CER1_HUMAN Cerberus (sprot)

A cerberus that is encoded in the genome of human.


FSTL1_HUMAN Follistatin-related protein 1 (sprot)

A follistatin-related protein 1 that is encoded in the genome of human.


CRDL1_HUMAN Chordin-like protein 1 (sprot)

A chordin-like protein 1 that is encoded in the genome of human.


GREM2_HUMAN Gremlin-2 (sprot)

A gremlin-2 that is encoded in the genome of human.


DCNL3_HUMAN DCN1-like protein 3 (sprot)

A DCN1-like protein 3 that is encoded in the genome of human.


DCNL2_HUMAN DCN1-like protein 2 (sprot)

A DCN1-like protein 2 that is encoded in the genome of human.


DCNL4_HUMAN DCN1-like protein 4 (sprot)

A DCN1-like protein 4 that is encoded in the genome of human.


DCNL1_HUMAN DCN1-like protein 1 (sprot)

A DCN1-like protein 1 that is encoded in the genome of human.


DCNL5_HUMAN DCN1-like protein 5 (sprot)

A DCN1-like protein 5 that is encoded in the genome of human.


NOSIP_HUMAN Nitric oxide synthase-interacting protein (sprot)

A nitric oxide synthase-interacting protein that is encoded in the genome of human.


BLNK_HUMAN B-cell linker protein (sprot)

A B-cell linker protein that is encoded in the genome of human.


o-Phthalaldehyde

A dialdehyde in which two formyl groups are attached to adjacent carbon centres on a benzene ring.


Octyl gallate

A gallate ester obtained by condensation of the carboxy group of gallic acid with the hydroxy group of octanol.


TRIFLUMIZOLE

A carboxamidine resulting from the formal condensation of the amino group of 4-chloro-2-(trifluoromethyl)aniline with the oxygen of the acetyl group of N-(propoxyacetyl)imidazole. A sterol demethylation inhibitor, it is used as a fungicide for the control of powdery mildew, scab and other diseases on a variety of crops.


A member of the class of phenols carrying two tert-butyl substituents at positions 2 and 4.


A member of the class of phenols carrying two tert-butyl substituents at positions 2 and 6.


Methyl linoleate

A  fatty acid methyl ester of  linoleic acid. It has been isolated from Neolitsea daibuensis.


Methyltrioctylammonium chloride

An organic chloride salt having methyltrioctylammonium as the cation.


Kathon 930

A 1,2-thiazole that is 1,2-thiazol-3(2H)-one substituted by chloro groups at positions 4 and 5 and an octyl group at position 2. It is used as a fungicide.


Fast Green FCF

An organic sodium salt having 2-{(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)[4-{ethyl[(3-sulfonatophenyl)methyl]iminio}cyclohexa-2,5-dien-1-ylidene]methyl}-5-hydroxybenzene-1-sulfonate as the counterion. Used as a substitute for Light green SF yellowish in Masson's trichrome as it is less likely to fade, and is more brilliant in colour. Also used as a food colouring agent.


Cetrimonium

A quaternary ammonium ion in which the substituents on nitrogen are one hexadecyl and three methyl groups.


Sotradecol

An organic sodium salt having tetradecyl sulfate as the counterion. Used in the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves.


Direct red 81

An organic sodium salt resulting from the formal condensation of Sirius red 4B (acid form) with two equivalents of sodium hydroxide. Used as the plasma stain in some trichrome staining methods.


Eosin

An organic sodium salt that is 2',4',5',7'-tetrabromofluorescein in which the carboxy group and the phenolic hydroxy group have been deprotonated and the resulting charge is neutralised by two sodium ions.


Dodecyltrimethylammonium

A quarternary ammonium cation having one dodecyl and three methyl substituents around the central nitrogen.


Tribromsalan

A salicylanilide derivative with bromo- substituents at C-3 and C-5 of the salicylate moiety and at C-4 of the anilide moiety.


A nitrotyrosine comprising tyrosine having a nitro group at the 3-position on the phenyl ring.


Bromophenol Blue

3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye.


Perchlorate

A monovalent inorganic anion obtained by deprotonation of perchloric acid.


Mancozeb

A mixture composed from maneb and zineb, which is used as a broad-spectrum contact fungicide.


1,3-Benzothiazole substituted at the 2-position with a sulfanyl group.


Zineb

A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU.


regulatory ncRNA-mediated gene silencing

A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.


GRB14_HUMAN Growth factor receptor-bound protein 14 (sprot)

A growth factor receptor-bound protein 14 that is encoded in the genome of human.


DOK2_HUMAN Docking protein 2 (sprot)

A docking protein 2 that is encoded in the genome of human.


2-Bromohexadecanoic acid

A bromo fatty acid that is hexadecanoic (palmitic) acid carrying a single bromo substituent at position 2.


Talarozole

A member of the class of benzothiazoles that is 2-amino-1,3-benzothiazole in which one of the amino hydrogens is replaced by a 4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl group.


Isobavachalcone

A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4' and a prenyl group at position 3'.


Cyclohexene

A cycloalkene that is cylohexane with a single double bond.


An alkanethiol that is propane substituted by a thiol group at position 1.


An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.


A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor.


brefeldin A

A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.


Betulin

A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-hydroxymethyl substituents.


Cycloserine

A 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and  D-alanine--D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis).


Methenamine

A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.


Psorospermin

An organic heterotetracyclic compound that is 1,2-dihydro-6H-furo[2,3-c]xanthene substituted by a hydroxy group at position 10, a methoxy group at position 5 nad a 2-methyloxiran-2-yl group at position 2.


Brequinar

A quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. The compound exhibits antineoplastic and antiviral properties.


MED12_HUMAN Mediator of RNA polymerase II transcription subunit 12 (sprot)

A mediator of RNA polymerase II transcription subunit 12 that is encoded in the genome of human.


MED4_HUMAN Mediator of RNA polymerase II transcription subunit 4 (sprot)

A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of human.


MED6_HUMAN Mediator of RNA polymerase II transcription subunit 6 (sprot)

A mediator of RNA polymerase II transcription subunit 6 that is encoded in the genome of human.


MED17_HUMAN Mediator of RNA polymerase II transcription subunit 17 (sprot)

A mediator of RNA polymerase II transcription subunit 17 that is encoded in the genome of human.


CCNC_HUMAN Cyclin-C (sprot)

A cyclin-C that is encoded in the genome of human.


MED16_HUMAN Mediator of RNA polymerase II transcription subunit 16 (sprot)

A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of human.


MED10_HUMAN Mediator of RNA polymerase II transcription subunit 10 (sprot)

A mediator of RNA polymerase II transcription subunit 10 that is encoded in the genome of human.


MED8_HUMAN Mediator of RNA polymerase II transcription subunit 8 (sprot)

A mediator of RNA polymerase II transcription subunit 8 that is encoded in the genome of human.


MED14_HUMAN Mediator of RNA polymerase II transcription subunit 14 (sprot)

A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of human.


MED13_HUMAN Mediator of RNA polymerase II transcription subunit 13 (sprot)

A mediator of RNA polymerase II transcription subunit 13 that is encoded in the genome of human.


MED31_HUMAN Mediator of RNA polymerase II transcription subunit 31 (sprot)

A mediator of RNA polymerase II transcription subunit 31 that is encoded in the genome of human.


MED26_HUMAN Mediator of RNA polymerase II transcription subunit 26 (sprot)

A mediator of RNA polymerase II transcription subunit 26 that is encoded in the genome of human.


MED7_HUMAN Mediator of RNA polymerase II transcription subunit 7 (sprot)

A mediator of RNA polymerase II transcription subunit 7 that is encoded in the genome of human.


MED24_HUMAN Mediator of RNA polymerase II transcription subunit 24 (sprot)

A mediator of RNA polymerase II transcription subunit 24 that is encoded in the genome of human.


MED23_HUMAN Mediator of RNA polymerase II transcription subunit 23 (sprot)

A mediator of RNA polymerase II transcription subunit 23 that is encoded in the genome of human.


MED20_HUMAN Mediator of RNA polymerase II transcription subunit 20 (sprot)

A mediator of RNA polymerase II transcription subunit 20 that is encoded in the genome of human.


MED15_HUMAN Mediator of RNA polymerase II transcription subunit 15 (sprot)

A mediator of RNA polymerase II transcription subunit 15 that is encoded in the genome of human.


MED27_HUMAN Mediator of RNA polymerase II transcription subunit 27 (sprot)

A mediator of RNA polymerase II transcription subunit 27 that is encoded in the genome of human.


MED30_HUMAN Mediator of RNA polymerase II transcription subunit 30 (sprot)

A mediator of RNA polymerase II transcription subunit 30 that is encoded in the genome of human.


MED25_HUMAN Mediator of RNA polymerase II transcription subunit 25 (sprot)

A mediator of RNA polymerase II transcription subunit 25 that is encoded in the genome of human.


ZN320_HUMAN Zinc finger protein 320 (sprot)

A zinc finger protein 320 that is encoded in the genome of human.


Z804B_HUMAN Zinc finger protein 804B (sprot)

A zinc finger protein 804B that is encoded in the genome of human.


KRBA1_HUMAN Protein KRBA1 (sprot)

A protein KRBA1 that is encoded in the genome of human.


ZN840_HUMAN Putative zinc finger protein 840 (sprot)


ZN860_HUMAN Zinc finger protein 860 (sprot)

A zinc finger protein 860 that is encoded in the genome of human.


ZN233_HUMAN Zinc finger protein 233 (sprot)

A zinc finger protein 233 that is encoded in the genome of human.


ZN729_HUMAN Zinc finger protein 729 (sprot)

A zinc finger protein 729 that is encoded in the genome of human.


ZN726_HUMAN Zinc finger protein 726 (sprot)

A zinc finger protein 726 that is encoded in the genome of human.


ZN716_HUMAN Zinc finger protein 716 (sprot)

A zinc finger protein 716 that is encoded in the genome of human.


ZN839_HUMAN Zinc finger protein 839 (sprot)

A zinc finger protein 839 that is encoded in the genome of human.


ZN785_HUMAN Zinc finger protein 785 (sprot)

A zinc finger protein 785 that is encoded in the genome of human.


ZN724_HUMAN Zinc finger protein 724 (sprot)

A protein that is a translation product of the ZNF724 gene in human.


ZN727_HUMAN Putative zinc finger protein 727 (sprot)

A protein that is a translation product of the ZNF727 gene in human.


Z705G_HUMAN Putative zinc finger protein 705G (sprot)

A putative zinc finger protein 705G that is encoded in the genome of human.


Z705E_HUMAN Putative zinc finger protein 705EP (sprot)

A putative zinc finger protein 705EP that is encoded in the genome of human.


ZNF99_HUMAN Zinc finger protein 99 (sprot)

A zinc finger protein 99 that is encoded in the genome of human.


ZN736_HUMAN Zinc finger protein 736 (sprot)

A zinc finger protein 736 that is encoded in the genome of human.


ZN732_HUMAN Zinc finger protein 732 (sprot)

A zinc finger protein 732 that is encoded in the genome of human.


ZN195_HUMAN Zinc finger protein 195 (sprot)

A zinc finger protein 195 that is encoded in the genome of human.


ZN197_HUMAN Zinc finger protein 197 (sprot)

A zinc finger protein 197 that is encoded in the genome of human.


ZN213_HUMAN Zinc finger protein 213 (sprot)

A zinc finger protein 213 that is encoded in the genome of human.


ZN263_HUMAN Zinc finger protein 263 (sprot)

A zinc finger protein 263 that is encoded in the genome of human.


ZN264_HUMAN Zinc finger protein 264 (sprot)

A zinc finger protein 264 that is encoded in the genome of human.


ZN208_HUMAN Zinc finger protein 208 (sprot)

A zinc finger protein 208 that is encoded in the genome of human.