xenobiotic catabolic process

The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.


L-serine biosynthetic process

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The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.


proline catabolic process

The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.


The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.


triglyceride biosynthetic process

The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.


dolichol-linked oligosaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P.


fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate

The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.


lactose synthase activity

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Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.


pentose-phosphate shunt

The metabolic process in which glucose-6-phosphate is oxidized to form carbon dioxide (CO2) and ribulose 5-phosphate, coupled to reduction of NADP+ to NADPH; ribulose 5-P then enters a series of reactions that can yield biosynthetic precursors (ribose-5-phosphate and erythrose-4-phosphate) and glycolytic intermediates (fructose-6-phosphate and glyceraldehyde-3-phosphate).


5-phosphoribose 1-diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.


glucuronate catabolic process to xylulose 5-phosphate

The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.


fructose biosynthetic process

The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.


thyroid hormone generation

The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.


keratan sulfate biosynthetic process

The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.


oligosaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.


vitamin B6 metabolic process

The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


vitamin K metabolic process

The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.


pyruvate dehydrogenase (NAD+) activity

Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH.


glycosaminoglycan metabolic process

The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.


carboxylic acid transport

The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).


protein O-linked glycosylation

A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.


coenzyme A biosynthetic process

The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


creatine metabolic process

The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.


response to progesterone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.


bile acid biosynthetic process

The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.


carnitine biosynthetic process

The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.


thyroid hormone metabolic process

The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.


lipid digestion

The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.


branched-chain amino acid catabolic process

The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.


mitochondrial electron transport, ubiquinol to cytochrome c

The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.


selenium compound metabolic process

The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.


phosphatidic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.


glyoxylate metabolic process

The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.


tRNA splicing, via endonucleolytic cleavage and ligation

Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.


histidine catabolic process

The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


tyrosine catabolic process

The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.


heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.


tRNA 5'-leader removal

Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.


ketone body biosynthetic process

The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.


phagosome acidification

Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.


deoxyribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


rRNA pseudouridine synthesis

The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.


ketone body catabolic process

The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.


sodium-independent organic anion transport

The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


peptidyl-lysine modification to peptidyl-hypusine

The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.


linoleic acid metabolic process

The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.


fatty acid alpha-oxidation

A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.


short-chain fatty acid catabolic process

The chemical reactions and pathways resulting in the breakdown of a fatty acid with an aliphatic tail of less than 6 carbons.


androgen biosynthetic process

The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.


mitochondrial calcium ion transmembrane transport

The process in which a calcium ion (Ca2+) is transported across a mitochondrial membrane, into or out of the mitochondrion.


gamma-aminobutyric acid catabolic process

The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.


urea cycle

The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.


glycerol biosynthetic process

The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.


histamine biosynthetic process

The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.


gamma-aminobutyric acid biosynthetic process

The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.


L-methionine salvage from methylthioadenosine

The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.


prostanoid metabolic process

The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.


cardiolipin acyl-chain remodeling

Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.


Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.


Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.


Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.


Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.


cellular glucuronidation

The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor.


glutathione derivative biosynthetic process

The chemical reactions and pathways resulting in the formation of glutathione derivative.


3'-phosphoadenosine 5'-phosphosulfate metabolic process

The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.


nucleobase-containing small molecule metabolic process

The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.


transsulfuration

The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.


sulfide oxidation, using sulfide:quinone oxidoreductase

A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.


L-cysteine catabolic process

The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.


preassembly of GPI anchor in ER membrane

The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane.


mitochondrial electron transport, cytochrome c to oxygen

The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.


proton motive force-driven mitochondrial ATP synthesis

The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.


xylulose biosynthetic process

The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose.


UDP-glucuronate biosynthetic process

The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.


polysaccharide digestion

The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.


hexose transmembrane transport

The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule.


estrogen biosynthetic process

The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.


mineralocorticoid biosynthetic process

The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.


thiamine-containing compound metabolic process

The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.


riboflavin metabolic process

The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).


NAD metabolic process

The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.


NAD biosynthesis via nicotinamide riboside salvage pathway

The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.


pantothenate metabolic process

The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.


keratan sulfate catabolic process

The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.


alpha-linolenic acid metabolic process

The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.


catecholamine biosynthetic process

The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.


indolalkylamine biosynthetic process

The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.


hepoxilin metabolic process

The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.


lipoxin biosynthetic process

The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signaling molecule that has four conjugated double bonds and is derived from arachidonic acid.


zinc ion import into Golgi lumen

The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi lumen.


polyamine biosynthetic process

The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.


L-alpha-amino acid transmembrane transport

The directed movement of L-alpha-amino acid across a membrane.


tRNA aminoacylation for protein translation

The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.


serotonin catabolic process

The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.


NADPH regeneration

A metabolic process that generates a pool of NADPH by the reduction of NADP+.


fatty acid beta-oxidation using acyl-CoA oxidase

A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


pyrimidine nucleoside biosynthetic process

The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


nucleobase-containing small molecule interconversion

The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.


mitochondrial tRNA methylation

The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.


rRNA methylation

The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.


choline catabolic process

The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.


glucosamine catabolic process

The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.


galactose catabolic process

The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.


tryptophan catabolic process

The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.


ethanol oxidation

An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.


lysine catabolic process

The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.


pyrimidine nucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


purine-containing compound salvage

Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.


purine nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


L-threonine catabolic process to glycine

The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.


nucleobase-containing small molecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.


aspartate family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.


pyruvate family amino acid metabolic process

The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine.


glutamine family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.


intestinal hexose absorption

Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.


O-glycan processing

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.


3'-5' DNA helicase activity

Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.


DNA helicase activity

Unwinding of a DNA helix, driven by ATP hydrolysis.


5'-3' DNA helicase activity

Unwinding a DNA helix in the 5' to 3' direction, driven by ATP hydrolysis.


3-keto sterol reductase activity

Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H+.


delta24-sterol reductase activity

Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.


C-4 methylsterol oxidase activity

Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(II)-[cytochrome b5] + 5 H+ + 3 O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O.


lanosterol synthase activity

Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.


sterol 14-demethylase activity

Catalysis of the reaction: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = a delta14 steroid + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].


delta14-sterol reductase activity

Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.


hydrolase activity, hydrolyzing O-glycosyl compounds

Catalysis of the hydrolysis of any O-glycosyl bond.


beta-mannosidase activity

Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.


carboxylic acid transmembrane transporter activity

Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).


Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.


thiamine pyrophosphate transmembrane transporter activity

Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.


dephospho-CoA kinase activity

Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H+.


Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.


biotinidase activity

Catalysis of the reaction: biotin amide + H2O = biotin + NH3.


protoheme IX farnesyltransferase activity

Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme O + diphosphate.


oxidoreductase activity, acting on the CH-CH group of donors

Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H+ + phosphatidyl-N-methylethanolamine.


Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.


calcium-dependent protein serine/threonine phosphatase activity

Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.


Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactoside = N-acetyl-alpha-neuraminyl-(2->6)-beta-D-galactosyl derivative + CMP + H+.


DNA N-glycosylase activity

Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.


Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.


Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.


Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.


Catalysis of the reaction: a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H+ + oxidized [electron-transfer flavoprotein].


oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

Catalysis of an oxidation-reduction in which the metal ion is reduced and NAD+ or NADP+ acts as an electron acceptor.


acetyl-CoA hydrolase activity

Catalysis of the reaction: acetyl-CoA + H2O = acetate + CoA + H+.


N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity

Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.


steroid 11-beta-monooxygenase activity

Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.


steroid 17-alpha-monooxygenase activity

Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O.


carbamoyl-phosphate synthase (ammonia) activity

Catalysis of the reaction: 2 ATP + hydrogencarbonate + NH4+ = 2 ADP + carbamoyl phosphate + 2 H+ + phosphate.


thromboxane-A synthase activity

Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).


L-ornithine transmembrane transporter activity

Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.


Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.


phosphatidylglycerophosphatase activity

Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.


Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H+.


5'-3' DNA/RNA helicase activity

Unwinding of a DNA/RNA duplex in the 5' to 3' direction, driven by ATP hydrolysis.


glycine N-benzoyltransferase activity

Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H+.


testosterone dehydrogenase [NAD(P)] activity

Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.


C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity

Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.


steroid 21-monooxygenase activity

Catalysis of the reaction: A C(21) steroid + [reduced NADPH--hemoprotein reductase] + O2 = a 21-hydroxy-C(21)-steroid + [oxidized NADPH--hemoprotein reductase] + H2O.


Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.


methylenetetrahydrofolate dehydrogenase (NAD+) activity

Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD+ = 5,10-methenyltetrahydrofolate + NADH.


prostaglandin-I synthase activity

Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).


chondroitin 4-sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.


pyruvate dehydrogenase (acetyl-transferring) kinase activity

Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate.


acetate CoA-transferase activity

Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.


S-adenosyl-L-methionine transmembrane transporter activity

Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.


12-hydroxyheptadecatrienoic acid synthase activity

Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA).


11-hydroxythromboxane B2 dehydrogenase activity

Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.


O-palmitoyltransferase activity

Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule.


acetylcholine transmembrane transporter activity

Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.


pristanate-CoA ligase activity

Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.


glyoxylate reductase (NADP+) activity

Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.


CMP-N-acetylneuraminate transmembrane transporter activity

Enables the transfer of a CMP-N-acetylneuraminate from one side of a membrane to the other.


Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.


alpha-1,2-mannosyltransferase activity

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.


Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol.


glycolipid floppase activity

Catalysis of the movement of a glycolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


alpha-1,3-mannosyltransferase activity

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.


alpha-1,6-mannosyltransferase activity

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.


Glc3Man9GlcNAc2 oligosaccharide glucosidase activity

Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).


5'-3' RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.


GDP-fucose transmembrane transporter activity

Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.


Catalysis of the dimethylation of two adjacent adenine residues in a rRNA, using S-adenosyl-L-methionine as a methyl donor.


rRNA (pseudouridine) methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.


methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity

Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+. Can also use malonate (3-oxopropanoate) as a substrate. The reaction occurs in two steps with the decarboxylation process preceding CoA-binding. Bicarbonate rather than CO2 is released as a final product.


methylmalonyl-CoA epimerase activity

Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.


Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.


Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.


Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.


Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.


keratan sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.


Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide.


alpha-N-acetylglucosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.


beta-galactosidase activity

Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.


Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.


L-iduronidase activity

Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.


phosphotransferase activity, for other substituted phosphate groups

Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).


ATP-dependent NAD(P)H-hydrate dehydratase activity

Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H+ + NADH + phosphate.


Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA.


linoleoyl-CoA desaturase activity

Catalysis of the reaction: (9Z,12Z)-octadecadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = (6Z,9Z,12Z)-octadecatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-CoA and add a fourth double bond (a (6Z,9Z,12Z,15Z)-octadecatetraenoyl-CoA).


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.


galactosylceramidase activity

Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.


glycolipid mannosyltransferase activity

Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.


Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.


Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.


CoA hydrolase activity

Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.


omega-6 fatty acid desaturase activity

Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.


Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.


3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity

Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.


Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n.


3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity

Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.


Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.


carnitine O-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA.


3'-5'-DNA exonuclease activity

Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R.


Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine.


Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.


Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.


cyclin-dependent protein serine/threonine kinase regulator activity

Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.


DNA-(apurinic or apyrimidinic site) endonuclease activity

Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).


5'-3' exonuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.


protein C-terminal methylesterase activity

Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.


oxidized purine nucleobase lesion DNA N-glycosylase activity

Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.


N-acetyltransferase activity

Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.


SUMO activating enzyme activity

Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.


histone H3K9 demethylase activity

Catalysis of the removal of a methyl group from a modified lysine residue at position 9 of the histone H3 protein.


cholesterol monooxygenase (side-chain-cleaving) activity

Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.


oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity

Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.


single-strand selective uracil DNA N-glycosylase activity

Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.


glycosylphosphatidylinositol phospholipase D activity

Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol.


NADPH-hemoprotein reductase activity

Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.


Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.


retinol isomerase activity

Catalysis of the reaction: all-trans-retinol = 11-cis-retinol.


peptide N-acetyltransferase activity

Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.


lipoyl(octanoyl) transferase activity

Catalysis of the reaction: L-lysyl-[protein] + octanoyl-[ACP] = H+ + holo-[ACP] + N6-octanoyl-L-lysyl-[protein].


DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates

Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.


polynucleotide 3'-phosphatase activity

Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.


aminomethyltransferase activity

Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.


lysozyme activity

Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.


protein C-terminal leucine carboxyl O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.


alpha-glucosidase activity

Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.


[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity

Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.


AKAP5_HUMAN A-kinase anchor protein 5 (sprot)

An A-kinase anchor protein 5 that is encoded in the genome of human.


Thymine

A pyrimidine nucleobase that is uracil in which the hydrogen at position 5 is replaced by a methyl group.


Thymidine

A pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase.


GRP75_HUMAN Stress-70 protein, mitochondrial (sprot)

A stress-70 protein, mitochondrial that is encoded in the genome of human.


Cupric cation

An ion of copper carrying a double positive charge.


Adenine

The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6.


Zwitterionic form of L-leucine.


ZO1_HUMAN Tight junction protein ZO-1 (sprot)

A tight junction protein ZO-1 that is encoded in the genome of human.


Beta-Carotene

A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid.


IDH3G_HUMAN Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (sprot)

An isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial that is encoded in the genome of human.


N-Acetyl-L-aspartic acid

An N-acyl-L-aspartic acid in which the acyl group is specified as acetyl.


A pantothenate that is the conjugate base of (R)-pantothenic acid, obtained by deprotonation of the carboxy group.


Pyridoxal

A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.


Pyridoxine

A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.


A zwitterionic form of N(6),N(6),N(6)-trimethyl-L-lysinium cation arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3


Nicotinic acid

A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.


N-acetyl-L-aspartyl-L-glutamate

A peptide anion obtained by deprotonation of the three carboxy groups of N-acetyl-Asp-Glu; major species at pH 7.3.


A nucleotide-sugar oxoanion that is the dianion of ADP-D-ribose(2-) arising from deprotonation of the phosphate OH groups; major species at pH 7.3.


peptide

Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.


An acetylspermidine having the acetyl group at the N1-position.


Trication of N(1)-acetylspermine arising from protonation of the one primary and two secondary amino groups; major species at pH 7.3.


Tyramine

A primary amino compound obtained by formal decarboxylation of the amino acid tyrosine.


An aldehyde that is acetaldehyde substituted by a 5-hydroxyindol-3-yl group.


The 5-phosphonooxy derivative of L-lysine having erythro-stereochemistry.


phosphate monoester

An organic phosphate that is phosphoric acid in which one of the hydrogens is replaced by an organyl group.


S-Formylglutathione

A S-acylglutathione in which the acyl group specified is formyl.


Acetaminophen sulfate

An aryl sulfate that is paracetamol in which the hydroxy group has been replaced by a sulfooxy group.


Dehydroepiandrosterone

An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.


[3H]dehydroepiandrosterone sulfate

The conjugate base of 3beta-hydroxyandrost-5-en-17-one 3-sulfate arising from deprotonation of the sulfate OH group; major species at pH 7.3.


Pregnenolone

A 20-oxo steroid that is pregn-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 20.


An oxysterol that is cholesterol substituted at position 26 by a hydroxy group.


A member of the class of 4-nitrophenols that is phenol in which the hydrogen that is para to the hydroxy group has been replaced by a nitro group.


Estrone

A 17-oxo steroid that is estra-1,3,5(10)-triene substituted by an hydroxy group at position 3 and an oxo group at position 17.


Methylarsonous acid

A one-carbon compound that is arsonous acid in which the hydrogen attached to arsenic is replaced by a methyl group.


Cysteamine

An amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2.


acylglucosaminylphosphatidylinositol

An inositol compound having acylglucosaminyl and phosphatidyl substituents on its hydroxy groups.


S-Methyl-L-methionine

A sulfonium compound that is the conjugate acid of S-methyl-L-methioninate.


S-[(2E,6E)-farnesyl]-L-cysteine residue

An alpha-amino-acid residue derived from S-[(2E,6E)-farnesyl]-L-cysteine


A hexadecenal containing a double bond at position 2 (the trans-stereoisomer).


globoside

Any glycosphingolipid where the oligosaccharide component has an N-acetylgalactosaminyl residue at the non-reducing end.


glycerophospholipid

Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone.


A monocarboxylic acid anion that is the conjugate base of  N-acetyl-L-cysteine, obtained by deprotonation of the carboxy group; major species at pH 7.3.


An inositol having myo- configuration substituted at position 1 by a phosphate group.


Glucose 6-phosphate

A glucopyranose ring with a phosphate replacing the hydroxy in the hydroxymethyl group at position 6.


limit dextrin

Limit dextrin is the remaining polymer produced by enzymatic hydrolysis of amylopectine with an amylase.


Brachiose

A glycosylglucose consisting of two D-glucopyranose units connected by an alpha-(1->6)-linkage.


A hydroxypregnenolone carrying an alpha-hydroxy group at position 17.


A cholestanoyl-CoA formed by thioester linkage between 3alpha,7alpha-dihydroxy-5beta-cholestan-26-oic acid and coenzyme A.


A 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA in which the carbon at position 25 of the steroidal side chain has S configuration.


A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.


UDP-alpha-D-xylose

Dianion of UDP-alpha-D-xylose arising from deprotonation of both free diphosphate OH groups.


Folic Acid

An N-acyl-amino acid that is a form of the water-soluble vitamin B9. Its biologically active forms (tetrahydrofolate and others) are essential for nucleotide biosynthesis and homocysteine remethylation.


(R)-Nadphx

A tetrahydronicotinamide adenine dinucleotide obtained by formal stero- and regioselective hydration across the 2,3-double bond in the nicotinyl ring of NADPH, with the hydroxy group located at position 2, having (R)-configuration.


GlcNAc-Gal-GlcNAc(S)-Gal

An amino tetrasaccharide comprised of two N-acetylated glucosamine residues, of which one is sulfated on O-6, and two galactosyl residues, of which one is at the reducing end. It is an intermediate in the keratan sulfate degradation pathway.


A linear heptasaccharide glycosyl group consisting of two N-acetylgalactosamine residues (both sulfated at the 4-position), one iduronic acid residue sulfated at the 2-position, one glucuronic acid residue and two galactosyl residues linked to a xylosyl residue at the reducing end.


An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3.


Ethanol

A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.


Cocaine

A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.


A pyridine nucleoside consisting of 1,4-dihydronicotinamide with a beta-D-ribofuranosyl moiety at the 1-position.


quinone

Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).


Benzylaminium

The conjugate acid of benzylamine; major product at pH 7.3.


Meadowlactone

A delta-lactone obtained by intramolecular condensation of the 5-hydroxy and carboxy groups of 5-hydroxyicosanoic acid. A nonenzymatic oxidation product of arachidonic acid.


Anandamide

An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine.


Methimazole

A member of the class of imidazoles that it imidazole-2-thione in which a methyl group replaces the hydrogen which is attached to a nitrogen.


Trimethylamine

A tertiary amine that is ammonia in which each hydrogen atom is substituted by an methyl group.


L-selenomethionine

The L-enantiomer of selenomethionine.


A 2'-deoxyribonucleoside triphosphate oxoanion that is the tetraanion of 8-oxo-dGTP arising from deprotonation of the triphosphate OH groups. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).


Major microspecies at pH 7.3.


Deoxyinosine diphosphate

A 2'-deoxyribonucleoside 5'-diphosphate obtained by deprotonation of the diphosphate OH groups of 2'-deoxyinosine  5'-diphosphate; major species at pH 7.3.


A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of 2-oxo-ATP; major microspecies at pH 7.3


Major microspecies at pH 7.3


A 2'-deoxyribonucleoside triphosphate oxoanion that is the tetraanion of 2'-deoxy-2-hydroxyadenosine 5'-triphosphate, arising from deprotonation of the triphosphate OH groups. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.).


Se-methylselenocysteine

An L-alpha-amino acid compound having methylselanylmethyl as the side-chain.


Iron, isotope of mass 56

An iron group element atom that has atomic number 26.


Zwitterionic form of L-threonine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3.


A monomethoxybenzene that is dopamine in which the hydroxy group at position 3 is replaced by a methoxy group. It is a metabolite of the neurotransmitter dopamine and considered a potential biomarker of pheochromocytomas and paragangliomas.


An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-isoleucine; major species at pH 7.3.


The L-enantiomer of histidinium(1+).


The amino acid zwitterion formed from 4-hydroxy-L-proline. It is the major microspecies present at pH 7.3.


D-Aspartic acid

The D-enantiomer of aspartic acid.


Pristanoyl-CoA in which C-2 of the pristanoyl group has S-configuration.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of cis-3-octenoic acid.


2-Hydroxyhexadecanoic acid

A 2-hydroxy fatty acid comprising a C16 straight chain carrying a hydroxy substituent at position 2.


Cystine

The L-enantiomer of the sulfur-containing amino acid cystine.


A trisaccharide consisting of D-glucuronic acid, alpha-D-xylosyl and D-glucuronic acid residues joined in sequence by (1->3)-linkages. A repeating unit in glycoprotein DAG1


A glycosylglucopyranuronic acid consisting of alpha-D-xylosyl and D-glucuronic acid residues joined by a (1->3)-linkage. A repeating structure in glycoproteins.


IdCTP

A 2'-deoxycytidine phosphate that is 2'-deoxycytidine-5'-triphosphate in which the hydrogen at position 5 on the cytosine ring is replaced by iodine.


aflatoxin B1 dialdehyde

A 1,4-dialdehyde compound having a hydroxy substituent at the 2-position and a 7-hydroxy-9-methoxy-3,4-dioxo-1,4-dihydro-3H-furo[3,4-c]chromen-6-yl group at the 3-position.


Aflatoxin B1 endo-8,9-epoxide

A member of the class of aflatoxins that is obtained by the formal epoxidation across the 8,9-double bond of aflatoxin B1.


Sorbitol

The D-enantiomer of glucitol (also known as D-sorbitol).


L-gulonate

The L-enantiomer of gulonate.


A medium-chain unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of cis,cis-dodeca-3,6-dienoic acid.


alpha-L-fucopyranose

An L-fucopyranose having alpha-configuration at the anomeric centre.


A GDP-sugar having 4-dehydro-6-deoxy-alpha-D-mannose as the sugar portion.


L-threonylcarbamoyladenylate

A threonine derivative that is L-threonine in which one of the amino hydrogens is substituted by and adenyloxycarbonyl group


Methylglyoxal

A 2-oxo aldehyde derived from propanal.


(R)-S-lactoylglutathione

The S-[(R)-lactoyl] derivative of glutathione. It is an intermediate in the pyruvate metabolism.


Urocanic acid

A urocanic acid in which the double bond of the carboxyethene moiety has E configuration.


S-(Hydroxymethyl)glutathione

An S-substituted glutathione that is glutathione in which the mercapto hydrogen has been replaced by a hydroxymethyl group.


2-deoxy-alpha-D-ribose 1-phosphate(2-)

Dianion of 2-deoxy-alpha-D-ribose 1-phosphate.


Pseudouridine 5'-phosphate

A C-nucleoside phosphate consisting of pseudouridine having a monophosphate group at the 5'-position.


A methyladenosine compound with one methyl group attached to N(6) of the adenine nucleobase.


XTP tetraanion

A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of XTP; major species present at pH 7.3.


dITP tetraanion

A 2'-deoxyribonucleoside 5'-triphosphate(4-) that is the tetraanion of 2'-deoxyinosine 5'-triphosphate(dITP), arising from deprotonation of the four free OH groups of the triphosphate; major species at pH 7.3.


ITP tetraanion

A nucleoside triphosphate(4-) obtained by global deprotonation of the triphosphate OH groups of ITP; major species present at pH 7.3.


The conjugate base of (R)-3-hydroxybutyric acid.


medium-chain fatty acyl-CoA

A fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any medium-chain fatty acid.


long-chain fatty acyl-CoA

A fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any long-chain (C13 to C22) fatty acid.


GlcNAc (Man)9

A ten-membered branched glucosamine oligosaccharide consisting of nine D-mannosyl residues and one N-acetylglucosamine residue (the latter being located at the reducing end). An intermediate glycan structure of glycosylated proteins


Geranylgeranyl diphosphate

The all-trans-isomer of geranylgeranyl diphosphate.


A 2'-deoxyribonucleoside triphosphate oxoanion being the tetraanion formed by global deprotonation of the triphosphate group.


phytosterols

Sterols similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond.


A dicarboxylic acid dianion resuting from removal of a proton from both carboxy groups of 4-fumarylacetoacetic acid.


Homogentisate

A dihydroxy monocarboxylic acid anion that is the conjugate base of (2,6-dihydroxyphenyl)acetic (homogentisic) acid, arising from deprotonation of the carboxy group.


Aspartame

A dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener.


An alpha-D-galactosyl group derived from alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-D-Gal-yl group. The blood group O (H) antigen from which subsequent sugar additions form blood groups A, B and AB


An alpha-D-galactosyl group derived from alpha-L-Fuc-(1->2)-beta-D-Gal-(1->3)-beta-D-GlcNAc-(1->3)-alpha-D-Gal-yl group. The H (O) antigen formed from a Type 1 precursor chain.


An N(4)-glycosylated asparagine residue in which the glycan moiety is a branched octasaccharide consisting of five D-mannosyl residues and three N-acetylglucosamine residues, one of which at the reducing end is bonded to the asparagine N(4) atom.


Pyridoxamine

A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy.


Ribavirin 5'-diphosphate(3-)

An organophosphate oxoanion resulting from the removal of the three diphosphate OH groups of  ribavirin 5'-diphosphate. It is the major species at pH 7.3.


N-glycan

The term used to refer to the carbohydrate portion of N-glycoproteins when attached to a nitrogen from asparagine or arginine side-chains.


A zwitterion formed from ciprofloxacin by transfer of a proton from the carboxy to the amino group; major species at pH 7.3.


L-Cysteic acid

The L-enantiomer of cysteic acid.


STX4_HUMAN Syntaxin-4 (sprot)

A syntaxin-4 that is encoded in the genome of human.


Palmitoylethanolamide

An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.


n-Oleoylethanolamine

An N-(long-chain-acyl)ethanolamine that is the ethanolamide of oleic acid. The monounsaturated analogue of the endocannabinoid anandamide.


A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.


conjugated protein

Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion.


BAP31_HUMAN B-cell receptor-associated protein 31 (sprot)

A B-cell receptor-associated protein 31 that is encoded in the genome of human.


LMNB1_HUMAN Lamin-B1 (sprot)

A lamin-B1 that is encoded in the genome of human.


amino-acid residue

When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue.


SERPH_HUMAN Serpin H1 (sprot)

A serpin H1 that is encoded in the genome of human.


SMD1_HUMAN Small nuclear ribonucleoprotein Sm D1 (sprot)

A small nuclear ribonucleoprotein Sm D1 that is encoded in the genome of human.


RUXF_HUMAN Small nuclear ribonucleoprotein F (sprot)

A small nuclear ribonucleoprotein F that is encoded in the genome of human.


RSMB_HUMAN Small nuclear ribonucleoprotein-associated proteins B and B' (sprot)

A small nuclear ribonucleoprotein-associated proteins B and B' that is encoded in the genome of human.


RUXG_HUMAN Small nuclear ribonucleoprotein G (sprot)

A small nuclear ribonucleoprotein G that is encoded in the genome of human.


SMD3_HUMAN Small nuclear ribonucleoprotein Sm D3 (sprot)

A small nuclear ribonucleoprotein Sm D3 that is encoded in the genome of human.


RUXE_HUMAN Small nuclear ribonucleoprotein E (sprot)

A small nuclear ribonucleoprotein E that is encoded in the genome of human.


SMD2_HUMAN Small nuclear ribonucleoprotein Sm D2 (sprot)

A small nuclear ribonucleoprotein Sm D2 that is encoded in the genome of human.


VAMP8_HUMAN Vesicle-associated membrane protein 8 (sprot)

A vesicle-associated membrane protein 8 that is encoded in the genome of human.


VAMP7_HUMAN Vesicle-associated membrane protein 7 (sprot)

A vesicle-associated membrane protein 7 that is encoded in the genome of human.


ZO2_HUMAN Tight junction protein ZO-2 (sprot)

A tight junction protein ZO-2 that is encoded in the genome of human.


GNAT1_HUMAN Guanine nucleotide-binding protein G(t) subunit alpha-1 (sprot)

A guanine nucleotide-binding protein G(t) subunit alpha-1 that is encoded in the genome of human.


prelamin-A/C isoform A (human)

A prelamin-A/C isoform A that is encoded in the genome of human.


PKP1_HUMAN Plakophilin-1 (sprot)

A plakophilin-1 that is encoded in the genome of human.


DESP_HUMAN Desmoplakin (sprot)

A desmoplakin that is encoded in the genome of human.


OCLN_HUMAN Occludin (sprot)

An occludin that is encoded in the genome of human.


2,3-trans-enoyl CoA(4-)

An acyl-CoA(4-) oxoanion arising from deprotonation of the phosphate and diphosphate OH groups of any 2,3-trans-enoyl CoA; major species at pH 7.3.


DLG1_HUMAN Disks large homolog 1 (sprot)

A disks large homolog 1 that is encoded in the genome of human.


E41L1_HUMAN Band 4.1-like protein 1 (sprot)

A band 4.1-like protein 1 that is encoded in the genome of human.


PRIC1_HUMAN Prickle-like protein 1 (sprot)

A prickle-like protein 1 that is encoded in the genome of human.


TRAF1_HUMAN TNF receptor-associated factor 1 (sprot)

A TNF receptor-associated factor 1 that is encoded in the genome of human.


An organic anionic group obtained by deprotonation of the phosphate OH group of N(1)-methylguanosine 5'-monophosphate residue.


adenosine residue

The nucleoside residue formed from adenosine with linkages at the 3' and 5' positions.


guanosine residue

The nucleoside residue formed from guanosine with linkages at the 3' and 5' positions.


IF4H_HUMAN Eukaryotic translation initiation factor 4H (sprot)

A eukaryotic translation initiation factor 4H that is encoded in the genome of human.


A hydroxy fatty acid anion that is the conjugate base of 3-hydroxybutyric acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.


VLDLR_HUMAN Very low-density lipoprotein receptor (sprot)

A very low-density lipoprotein receptor that is encoded in the genome of human.


EMRE_HUMAN Essential MCU regulator, mitochondrial (sprot)

An essential MCU regulator, mitochondrial that is encoded in the genome of human.


SODM_HUMAN Superoxide dismutase [Mn], mitochondrial (sprot)

A superoxide dismutase [Mn], mitochondrial that is encoded in the genome of human.


RHBT2_HUMAN Rho-related BTB domain-containing protein 2 (sprot)

A Rho-related BTB domain-containing protein 2 that is encoded in the genome of human.


H2A1C_HUMAN Histone H2A type 1-C (sprot)

A histone H2A type 1-C that is encoded in the genome of human.


N4BP1_HUMAN NEDD4-binding protein 1 (sprot)

A NEDD4-binding protein 1 that is encoded in the genome of human.


IMA8_HUMAN Importin subunit alpha-8 (sprot)

An importin subunit alpha-8 that is encoded in the genome of human.


IMA4_HUMAN Importin subunit alpha-4 (sprot)

An importin subunit alpha-4 that is encoded in the genome of human.


IMA6_HUMAN Importin subunit alpha-6 (sprot)

An importin subunit alpha-6 that is encoded in the genome of human.


CISY_HUMAN Citrate synthase, mitochondrial (sprot)

A citrate synthase, mitochondrial that is encoded in the genome of human.


DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial (sprot)

A glutamate dehydrogenase 1, mitochondrial that is encoded in the genome of human.


H2A1B_HUMAN Histone H2A type 1-B/E (sprot)

A histone H2A type 1-B/E that is encoded in the genome of human.


CY1_HUMAN Cytochrome c1, heme protein, mitochondrial (sprot)

A cytochrome c1, heme protein, mitochondrial that is encoded in the genome of human.


H2A1_HUMAN Histone H2A type 1 (sprot)

A histone H2A type 1-G/I/K/L/M that is encoded in the genome of human.


H2A1D_HUMAN Histone H2A type 1-D (sprot)

A histone H2A type 1-D that is encoded in the genome of human.


ATPA_HUMAN ATP synthase subunit alpha, mitochondrial (sprot)

An ATP synthase subunit alpha, mitochondrial that is encoded in the genome of human.


LYOX_HUMAN Protein-lysine 6-oxidase (sprot)

A protein-lysine 6-oxidase that is encoded in the genome of human.


IDHP_HUMAN Isocitrate dehydrogenase [NADP], mitochondrial (sprot)

An isocitrate dehydrogenase [NADP], mitochondrial that is encoded in the genome of human.


DHE4_HUMAN Glutamate dehydrogenase 2, mitochondrial (sprot)

A glutamate dehydrogenase 2, mitochondrial that is encoded in the genome of human.


LOXL1_HUMAN Lysyl oxidase homolog 1 (sprot)

A lysyl oxidase homolog 1 that is encoded in the genome of human.


H2A2C_HUMAN Histone H2A type 2-C (sprot)

A histone H2A type 2-C that is encoded in the genome of human.


H2A2A_HUMAN Histone H2A type 2-A (sprot)

A histone H2A type 2-A that is encoded in the genome of human.


H2A3_HUMAN Histone H2A type 3 (sprot)

A histone H2A type 3 that is encoded in the genome of human.


H2A2B_HUMAN Histone H2A type 2-B (sprot)

A histone H2A type 2-B that is encoded in the genome of human.


LOXL4_HUMAN Lysyl oxidase homolog 4 (sprot)

A lysyl oxidase homolog 4 that is encoded in the genome of human.


H2A1H_HUMAN Histone H2A type 1-H (sprot)

A histone H2A type 1-H that is encoded in the genome of human.


H2A1J_HUMAN Histone H2A type 1-J (sprot)

A histone H2A type 1-J that is encoded in the genome of human.


BCS1_HUMAN Mitochondrial chaperone BCS1 (sprot)

A mitochondrial chaperone BCS1 that is encoded in the genome of human.


LOXL2_HUMAN Lysyl oxidase homolog 2 (sprot)

A lysyl oxidase homolog 2 that is encoded in the genome of human.


D-alanine

The D-enantiomer of alanine.


Thioctic acid

A heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position.


A carbohydrate acid derivative anion that is the conjugate base of alpha-N-acetylneuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide arising from deprotonation of the neuraminosyl carboxy group; major species at pH 7.3.


3'-dUMP dianion

A 2'-deoxyribonucleoside 3'-monophosphate(2-) obtained by deprotonation of the phosphate OH groups of 2'-deoxyuridine 3'-monophosphate (3'-dUMP); major species at pH 7.3.


A sialodiosylceramide consisting of the tetrasaccharide alpha-Neu5NAc-(2->8)-alpha-Neu5NAc-(2->3)-beta-D-Gal-(1->4)-beta-D-Glc attached to the primary hydroxy function of ceramide.


Uridine 2'-phosphate(2-)

A organophosphate oxoanion obtained by deprotonation of the phosphate OH groups of uridine 2'-phosphate. Major structure at pH 7.3 (according to Marvin v 6.2.0.).


An anionic ganglioside obtained by deprotonation of the neuraminosyl carboxy groups of ganglioside GT3; major species at pH 7.3.


A nucleoside 3'-phosphate(2-) obtained by deprotonation of the phosphate OH groups of uridine 3'-monophosphate (UMP). It is the predominant species at physiological pH.


A dihexosylceramide sulfate(1-) obtained by deprotonation of the sulfate group of beta-D-3-sulfogalactosyl-(1->4)-beta-D-glucosyl-(1<->1')-ceramide; major species at pH 7.3.


An N-(long-chain-acyl)ethanolamine resulting from the formal condensation of the carboxy group of tetradecanoic acid (myristic acid) with the amino group of ethanolamine.


An N-(long-chain-acyl)ethanolamine resulting from the formal condensation of the carboxy group of dodecanoic acid (myristic acid) with the amino group of ethanolamine.


An N-acylethanolamine 18:0 that is the ethanolamide of octadecanoic acid.


An NADP obtained by formal reduction of the 1,2-position in the pyridine ring of beta-NAD.


An NADP obtained by formal reduction of the 1,6-position in the pyridine ring of beta-NAD.


PRP16_HUMAN Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 (sprot)

A pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 that is encoded in the genome of human.


GDS1_HUMAN Rap1 GTPase-GDP dissociation stimulator 1 (sprot)

A Rap1 GTPase-GDP dissociation stimulator 1 that is encoded in the genome of human.


FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 (sprot)

A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of human.


ARF1_HUMAN ADP-ribosylation factor 1 (sprot)

An ADP-ribosylation factor 1 that is encoded in the genome of human.


RN185_HUMAN E3 ubiquitin-protein ligase RNF185 (sprot)

An E3 ubiquitin-protein ligase RNF185 that is encoded in the genome of human.


KAT2B_HUMAN Histone acetyltransferase KAT2B (sprot)

A histone acetyltransferase KAT2B that is encoded in the genome of human.


S17A5_HUMAN Sialin (sprot)

A sialin that is encoded in the genome of human.


GALT2_HUMAN Polypeptide N-acetylgalactosaminyltransferase 2 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 2 that is encoded in the genome of human.


GALT4_HUMAN Polypeptide N-acetylgalactosaminyltransferase 4 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 4 that is encoded in the genome of human.


GALT1_HUMAN Polypeptide N-acetylgalactosaminyltransferase 1 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 1 that is encoded in the genome of human.


GALT3_HUMAN Polypeptide N-acetylgalactosaminyltransferase 3 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 3 that is encoded in the genome of human.


ZNT5_HUMAN Proton-coupled zinc antiporter SLC30A5 (sprot)

A proton-coupled zinc antiporter SLC30A5 that is encoded in the genome of human.


LGMN_HUMAN Legumain (sprot)

A legumain that is encoded in the genome of human.


SENP1_HUMAN Sentrin-specific protease 1 (sprot)

A sentrin-specific protease 1 that is encoded in the genome of human.


heparan sulfate

A linear polysaccharide in which the backbone consists of a variably sulfated repeating disaccharide unit.


KCJ11_HUMAN ATP-sensitive inward rectifier potassium channel 11 (sprot)

An ATP-sensitive inward rectifier potassium channel 11 that is encoded in the genome of human.


NEIL1_HUMAN Endonuclease 8-like 1 (sprot)

An endonuclease 8-like 1 that is encoded in the genome of human.


NTH_HUMAN Endonuclease III-like protein 1 (sprot)

An endonuclease III-like protein 1 that is encoded in the genome of human.


MBD4_HUMAN Methyl-CpG-binding domain protein 4 (sprot)

A methyl-CpG-binding domain protein 4 that is encoded in the genome of human.


OGG1_HUMAN N-glycosylase/DNA lyase (sprot)

An N-glycosylase/DNA lyase that is encoded in the genome of human.


NEIL2_HUMAN Endonuclease 8-like 2 (sprot)

An endonuclease 8-like 2 that is encoded in the genome of human.


uracil-DNA glycosylase isoform h2 (human)

A uracil-DNA glycosylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P13051-1.


SMUG1_HUMAN Single-strand selective monofunctional uracil DNA glycosylase (sprot)

A single-strand selective monofunctional uracil DNA glycosylase that is encoded in the genome of human.


3MG_HUMAN DNA-3-methyladenine glycosylase (sprot)

A DNA-3-methyladenine glycosylase that is encoded in the genome of human.


adenine DNA glycosylase isoform hAlpha-3 (human)

An adenine DNA glycosylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UIF7-3.


CTDP1_HUMAN RNA polymerase II subunit A C-terminal domain phosphatase (sprot)

An RNA polymerase II subunit A C-terminal domain phosphatase that is encoded in the genome of human.


ACRO_HUMAN Acrosin (sprot)

An acrosin that is encoded in the genome of human.


FACR2_HUMAN Fatty acyl-CoA reductase 2 (sprot)

A fatty acyl-CoA reductase 2 that is encoded in the genome of human.


FACR1_HUMAN Fatty acyl-CoA reductase 1 (sprot)

A fatty acyl-CoA reductase 1 that is encoded in the genome of human.


SOCS6_HUMAN Suppressor of cytokine signaling 6 (sprot)

A suppressor of cytokine signaling 6 that is encoded in the genome of human.


CRLS1_HUMAN Cardiolipin synthase (CMP-forming) (sprot)

A CMP-forming cardiolipin synthase that is encoded in the genome of human.


S27A5_HUMAN Long-chain fatty acid transport protein 5 (sprot)

A long-chain fatty acid transport protein 5 that is encoded in the genome of human.


UBIA1_HUMAN UbiA prenyltransferase domain-containing protein 1 (sprot)

A UbiA prenyltransferase domain-containing protein 1 that is encoded in the genome of human.


PIGA_HUMAN Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (sprot)

An N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein that is encoded in the genome of human.


PIGL_HUMAN N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (sprot)

An N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase that is encoded in the genome of human.


PIGW_HUMAN Phosphatidylinositol-glycan biosynthesis class W protein (sprot)

A phosphatidylinositol-glycan biosynthesis class W protein that is encoded in the genome of human.


GLR_HUMAN Glucagon receptor (sprot)

A glucagon receptor that is encoded in the genome of human.


SUMF1_HUMAN Formylglycine-generating enzyme (sprot)

A formylglycine-generating enzyme that is encoded in the genome of human.


PPM1L_HUMAN Protein phosphatase 1L (sprot)

A protein phosphatase 1L that is encoded in the genome of human.


P2Y12_HUMAN P2Y purinoceptor 12 (sprot)

A P2Y purinoceptor 12 that is encoded in the genome of human.


DNA2_HUMAN DNA replication ATP-dependent helicase/nuclease DNA2 (sprot)

A DNA replication ATP-dependent helicase/nuclease DNA2 that is encoded in the genome of human.


SUIS_HUMAN Sucrase-isomaltase, intestinal (sprot)

A sucrase-isomaltase, intestinal that is encoded in the genome of human.


feline leukemia virus subgroup C receptor-related protein 1 isoform h2 (human)

A feline leukemia virus subgroup C receptor-related protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y5Y0-2.


proto-oncogene tyrosine-protein kinase Src isoform 2 (human)

A proto-oncogene tyrosine-protein kinase Src isoform 2 that is encoded in the genome of human.


CP27A_HUMAN Sterol 26-hydroxylase, mitochondrial (sprot)

A cytochrome P450 27, mitochondrial that is encoded in the genome of human.


3BHS7_HUMAN 3 beta-hydroxysteroid dehydrogenase type 7 (sprot)

A 3 beta-hydroxysteroid dehydrogenase type 7 that is encoded in the genome of human.


AMACR_HUMAN Alpha-methylacyl-CoA racemase (sprot)

An alpha-methylacyl-CoA racemase that is encoded in the genome of human.


CP11A_HUMAN Cholesterol side-chain cleavage enzyme, mitochondrial (sprot)

A cytochrome P450 11A1, mitochondrial that is encoded in the genome of human.


CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (sprot)

A 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial that is encoded in the genome of human.


CP2R1_HUMAN Vitamin D 25-hydroxylase (sprot)

A vitamin D 25-hydroxylase that is encoded in the genome of human.


SC5D_HUMAN Lathosterol oxidase (sprot)

A lathosterol oxidase that is encoded in the genome of human.


S35A2_HUMAN UDP-galactose translocator (sprot)

A UDP-galactose translocator that is encoded in the genome of human.


B3GT6_HUMAN Beta-1,3-galactosyltransferase 6 (sprot)

A beta-1,3-galactosyltransferase 6 that is encoded in the genome of human.


GBF1_HUMAN Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (sprot)

A Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 that is encoded in the genome of human.


CP7A1_HUMAN Cytochrome P450 7A1 (sprot)

A cytochrome P450 7A1 that is encoded in the genome of human.


S35A3_HUMAN UDP-N-acetylglucosamine transporter (sprot)

A UDP-N-acetylglucosamine transporter that is encoded in the genome of human.


An N-acetylglucosamine-6-sulfatase that is encoded in the genome of human.


TIE2_HUMAN Angiopoietin-1 receptor (sprot)

An angiopoietin-1 receptor that is encoded in the genome of human.


CP2S1_HUMAN Cytochrome P450 2S1 (sprot)

A cytochrome P450 2S1 that is encoded in the genome of human.


IGF1R_HUMAN Insulin-like growth factor 1 receptor (sprot)

An insulin-like growth factor 1 receptor that is encoded in the genome of human.


RDH12_HUMAN Retinol dehydrogenase 12 (sprot)

A retinol dehydrogenase 12 that is encoded in the genome of human.


RET3_HUMAN Retinol-binding protein 3 (sprot)

A retinol-binding protein 3 that is encoded in the genome of human.


ABCA4_HUMAN Retinal-specific phospholipid-transporting ATPase ABCA4 (sprot)

A retinal-specific phospholipid-transporting ATPase ABCA4 that is encoded in the genome of human.


GRK1_HUMAN Rhodopsin kinase GRK1 (sprot)

A rhodopsin kinase GRK1 that is encoded in the genome of human.


MYO5A_HUMAN Unconventional myosin-Va (sprot)

A myosin-Va that is encoded in the genome of human.


ZNT8_HUMAN Proton-coupled zinc antiporter SLC30A8 (sprot)

A proton-coupled zinc antiporter SLC30A8 that is encoded in the genome of human.


SAE2_HUMAN SUMO-activating enzyme subunit 2 (sprot)

A SUMO-activating enzyme subunit 2 that is encoded in the genome of human.


ANM6_HUMAN Protein arginine N-methyltransferase 6 (sprot)

A protein arginine N-methyltransferase 6 that is encoded in the genome of human.


PORCN_HUMAN Protein-serine O-palmitoleoyltransferase porcupine (sprot)

A protein-serine O-palmitoleoyltransferase porcupine that is encoded in the genome of human.


ATP7A_HUMAN Copper-transporting ATPase 1 (sprot)

A copper-transporting ATPase 1 that is encoded in the genome of human.


SYVN1_HUMAN E3 ubiquitin-protein ligase synoviolin (sprot)

An E3 ubiquitin-protein ligase synoviolin that is encoded in the genome of human.


EDEM1_HUMAN ER degradation-enhancing alpha-mannosidase-like protein 1 (sprot)

An ER degradation-enhancing alpha-mannosidase-like protein 1 that is encoded in the genome of human.


PM34_HUMAN Peroxisomal membrane protein PMP34 (sprot)

A peroxisomal membrane protein PMP34 that is encoded in the genome of human.


LIPT2_HUMAN Putative lipoyltransferase 2, mitochondrial (sprot)

A putative lipoyltransferase 2, mitochondrial that is encoded in the genome of human.


ECHP_HUMAN Peroxisomal bifunctional enzyme (sprot)

A peroxisomal bifunctional enzyme that is encoded in the genome of human.


NEUR1_HUMAN Sialidase-1 (sprot)

A sialidase-1 that is encoded in the genome of human.


DOPP1_HUMAN Dolichyldiphosphatase 1 (sprot)

A dolichyldiphosphatase 1 that is encoded in the genome of human.


CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor (sprot)

A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of human.


LAAT1_HUMAN Lysosomal amino acid transporter 1 homolog (sprot)

A lysosomal amino acid transporter 1 homolog that is encoded in the genome of human.


PMS2_HUMAN Mismatch repair endonuclease PMS2 (sprot)

A mismatch repair endonuclease PMS2 that is encoded in the genome of human.


EXO1_HUMAN Exonuclease 1 (sprot)

An exonuclease 1 that is encoded in the genome of human.


CP2AD_HUMAN Cytochrome P450 2A13 (sprot)

A cytochrome P450 2A that is a translation product of the CYP2A13 gene in human.


FMT_HUMAN Methionyl-tRNA formyltransferase, mitochondrial (sprot)

A methionyl-tRNA formyltransferase, mitochondrial that is encoded in the genome of human.


KDM4C_HUMAN Lysine-specific demethylase 4C (sprot)

A lysine-specific demethylase 4C that is encoded in the genome of human.


KDM6A_HUMAN Lysine-specific demethylase 6A (sprot)

A lysine-specific demethylase 6A that is encoded in the genome of human.


PNKP_HUMAN Bifunctional polynucleotide phosphatase/kinase (sprot)

A bifunctional polynucleotide phosphatase/kinase that is encoded in the genome of human.


UBP30_HUMAN Ubiquitin carboxyl-terminal hydrolase 30 (sprot)

A ubiquitin carboxyl-terminal hydrolase 30 that is encoded in the genome of human.


UBP45_HUMAN Ubiquitin carboxyl-terminal hydrolase 45 (sprot)

A ubiquitin carboxyl-terminal hydrolase 45 that is encoded in the genome of human.


TRM5_HUMAN tRNA (guanine(37)-N1)-methyltransferase (sprot)

A tRNA (guanine-N(1)-)-methyltransferase that is encoded in the genome of human.


GCST_HUMAN Aminomethyltransferase, mitochondrial (sprot)

An aminomethyltransferase, mitochondrial that is encoded in the genome of human.


EXOSX_HUMAN Exosome component 10 (sprot)

An exosome component 10 that is encoded in the genome of human.


XRN2_HUMAN 5'-3' exoribonuclease 2 (sprot)

A 5'-3' exoribonuclease 2 that is encoded in the genome of human.


AL7A1_HUMAN Alpha-aminoadipic semialdehyde dehydrogenase (sprot)

An alpha-aminoadipic semialdehyde dehydrogenase that is encoded in the genome of human.


CHDH_HUMAN Choline dehydrogenase, mitochondrial (sprot)

A choline dehydrogenase, mitochondrial that is encoded in the genome of human.


RHBT3_HUMAN Rho-related BTB domain-containing protein 3 (sprot)

A Rho-related BTB domain-containing protein 3 that is encoded in the genome of human.


PP4P1_HUMAN Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (sprot)

A type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase that is encoded in the genome of human.


LCMT1_HUMAN Leucine carboxyl methyltransferase 1 (sprot)

A leucine carboxyl methyltransferase 1 that is encoded in the genome of human.


HYPDH_HUMAN Hydroxyproline dehydrogenase (sprot)

A hydroxyproline dehydrogenase that is encoded in the genome of human.


PROD_HUMAN Proline dehydrogenase 1, mitochondrial (sprot)

A proline dehydrogenase 1, mitochondrial that is encoded in the genome of human.


NAGS_HUMAN N-acetylglutamate synthase, mitochondrial (sprot)

An N-acetylglutamate synthase, mitochondrial that is encoded in the genome of human.


SOX_HUMAN Peroxisomal sarcosine oxidase (sprot)

A peroxisomal sarcosine oxidase that is encoded in the genome of human.


CRYM_HUMAN Ketimine reductase mu-crystallin (sprot)

A ketimine reductase mu-crystallin that is encoded in the genome of human.


S2544_HUMAN Solute carrier family 25 member 44 (sprot)

A solute carrier family 25 member 44 that is encoded in the genome of human.


DDX46_HUMAN Probable ATP-dependent RNA helicase DDX46 (sprot)

A probable ATP-dependent RNA helicase DDX46 that is encoded in the genome of human.


DDX23_HUMAN Probable ATP-dependent RNA helicase DDX23 (sprot)

A probable ATP-dependent RNA helicase DDX23 that is encoded in the genome of human.


U520_HUMAN U5 small nuclear ribonucleoprotein 200 kDa helicase (sprot)

A U5 small nuclear ribonucleoprotein 200 kDa helicase that is encoded in the genome of human.


ACSS3_HUMAN Acyl-CoA synthetase short-chain family member 3, mitochondrial (sprot)

An acyl-CoA synthetase short-chain family member 3, mitochondrial that is encoded in the genome of human.


RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret (sprot)

A proto-oncogene tyrosine-protein kinase receptor Ret that is encoded in the genome of human.


MTP_HUMAN Microsomal triglyceride transfer protein large subunit (sprot)

A microsomal triglyceride transfer protein large subunit that is encoded in the genome of human.


KMT2A_HUMAN Histone-lysine N-methyltransferase 2A (sprot)

A histone-lysine N-methyltransferase 2A that is encoded in the genome of human.


NAT8L_HUMAN N-acetylaspartate synthetase (sprot)

An N-acetylaspartate synthetase that is encoded in the genome of human.


NCEH1_HUMAN Neutral cholesterol ester hydrolase 1 (sprot)

A neutral cholesterol ester hydrolase 1 that is encoded in the genome of human.


LICH_HUMAN Lysosomal acid lipase/cholesteryl ester hydrolase (sprot)

A lysosomal acid lipase/cholesteryl ester hydrolase that is encoded in the genome of human.


LCAT_HUMAN Phosphatidylcholine-sterol acyltransferase (sprot)

A phosphatidylcholine-sterol acyltransferase that is encoded in the genome of human.


RHOU_HUMAN Rho-related GTP-binding protein RhoU (sprot)

A Rho-related GTP-binding protein RhoU that is encoded in the genome of human.


FUT1_HUMAN Galactoside alpha-(1,2)-fucosyltransferase 1 (sprot)

A galactoside alpha-(1,2)-fucosyltransferase 1 that is encoded in the genome of human.


CERU_HUMAN Ceruloplasmin (sprot)

A ceruloplasmin that is encoded in the genome of human.


AGRG6_HUMAN Adhesion G-protein coupled receptor G6 (sprot)

An adhesion G-protein coupled receptor G6 that is encoded in the genome of human.


SCN2A_HUMAN Sodium channel protein type 2 subunit alpha (sprot)

A sodium channel protein type 2 subunit alpha that is encoded in the genome of human.


SCN9A_HUMAN Sodium channel protein type 9 subunit alpha (sprot)

A sodium channel protein type 9 subunit alpha that is encoded in the genome of human.


SCN3A_HUMAN Sodium channel protein type 3 subunit alpha (sprot)

A sodium channel protein type 3 subunit alpha that is encoded in the genome of human.


An alpha-(1,6)-fucosyltransferase that is encoded in the genome of human.


TCO1_HUMAN Transcobalamin-1 (sprot)

A transcobalamin-1 that is encoded in the genome of human.


TCO2_HUMAN Transcobalamin-2 (sprot)

A transcobalamin-2 that is encoded in the genome of human.


MMAB_HUMAN Corrinoid adenosyltransferase MMAB (sprot)

A corrinoid adenosyltransferase MMAB that is encoded in the genome of human.


BACE1_HUMAN Beta-secretase 1 (sprot)

A beta-secretase 1 that is encoded in the genome of human.


DX39A_HUMAN ATP-dependent RNA helicase DDX39A (sprot)

An ATP-dependent RNA helicase DDX39 that is encoded in the genome of human.


RN103_HUMAN E3 ubiquitin-protein ligase RNF103 (sprot)

An E3 ubiquitin-protein ligase RNF103 that is encoded in the genome of human.


H17B6_HUMAN 17-beta-hydroxysteroid dehydrogenase type 6 (sprot)

A 17-beta-hydroxysteroid dehydrogenase type 6 that is encoded in the genome of human.


ATS3_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 3 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 3 that is encoded in the genome of human.


MARH6_HUMAN E3 ubiquitin-protein ligase MARCHF6 (sprot)

An E3 ubiquitin-protein ligase MARCHF6 that is encoded in the genome of human.


TPST1_HUMAN Protein-tyrosine sulfotransferase 1 (sprot)

A protein-tyrosine sulfotransferase 1 that is encoded in the genome of human.


TPST2_HUMAN Protein-tyrosine sulfotransferase 2 (sprot)

A protein-tyrosine sulfotransferase 2 that is encoded in the genome of human.


TRI13_HUMAN E3 ubiquitin-protein ligase TRIM13 (sprot)

An E3 ubiquitin-protein ligase TRIM13 that is encoded in the genome of human.


RDH16_HUMAN Retinol dehydrogenase 16 (sprot)

A retinol dehydrogenase 16 that is encoded in the genome of human.


CP7B1_HUMAN Cytochrome P450 7B1 (sprot)

A cytochrome P450 7B1 that is encoded in the genome of human.


ATS2_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 2 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 2 that is encoded in the genome of human.


NAPSA_HUMAN Napsin-A (sprot)

A napsin-A that is encoded in the genome of human.


AMYP_HUMAN Pancreatic alpha-amylase (sprot)

An alpha-amylase 2A that is encoded in the genome of human.


CATL1_HUMAN Procathepsin L (sprot)

A procathepsin L that is encoded in the genome of human.


CATH_HUMAN Pro-cathepsin H (sprot)

A cathepsin H that is encoded in the genome of human.


PEPA4_HUMAN Pepsin A-4 (sprot)

A pepsin A-4 that is encoded in the genome of human.


PEPA3_HUMAN Pepsin A-3 (sprot)

A pepsin A-3 that is encoded in the genome of human.


PEPA5_HUMAN Pepsin A-5 (sprot)

A pepsin A-5 that is encoded in the genome of human.


AMY1B_HUMAN Alpha-amylase 1B (sprot)

A protein that is a translation product of the AMY1B gene in human.


AMY1C_HUMAN Alpha-amylase 1C (sprot)

A protein that is a translation product of the AMY1C gene in human.


AMY1A_HUMAN Alpha-amylase 1A (sprot)

A protein that is a translation product of the AMY1A gene in human.


PPGB_HUMAN Lysosomal protective protein (sprot)

A lysosomal protective protein that is encoded in the genome of human.


CP2A6_HUMAN Cytochrome P450 2A6 (sprot)

A cytochrome P450 2A that is a translation product of the CYP2A6 gene in human.


CATE_HUMAN Cathepsin E (sprot)

A cathepsin E that is encoded in the genome of human.


AMY2B_HUMAN Alpha-amylase 2B (sprot)

An alpha-amylase 2B that is encoded in the genome of human.


CP2B6_HUMAN Cytochrome P450 2B6 (sprot)

A cytochrome P450 2B6 that is encoded in the genome of human.


CP3A5_HUMAN Cytochrome P450 3A5 (sprot)

A cytochrome P450 3A5 that is encoded in the genome of human.


CP2A7_HUMAN Cytochrome P450 2A7 (sprot)

A cytochrome P450 2A that is a translation product of the CYP2A7 gene in human.


CP2F1_HUMAN Cytochrome P450 2F1 (sprot)

A cytochrome P450 2F1 that is encoded in the genome of human.


HMOX2_HUMAN Heme oxygenase 2 (sprot)

A heme oxygenase 2 that is encoded in the genome of human.


G protein-coupled receptor kinase 4 isoform h1 (human)

A G protein-coupled receptor kinase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P32298-1.


TRY3_HUMAN Trypsin-3 (sprot)

A trypsin-3 that is encoded in the genome of human.


CATO_HUMAN Cathepsin O (sprot)

A cathepsin O that is encoded in the genome of human.


GRK6_HUMAN G protein-coupled receptor kinase 6 (sprot)

A G protein-coupled receptor kinase 6 that is encoded in the genome of human.


VDAC2_HUMAN Voltage-dependent anion-selective channel protein 2 (sprot)

A voltage-dependent anion-selective channel protein 2 that is encoded in the genome of human.


GUC2F_HUMAN Retinal guanylyl cyclase 2 (sprot)

A retinal guanylyl cyclase 2 that is encoded in the genome of human.


CATC_HUMAN Dipeptidyl peptidase 1 (sprot)

A dipeptidyl peptidase 1 that is encoded in the genome of human.


ARF3_HUMAN ADP-ribosylation factor 3 (sprot)

An ADP-ribosylation factor 3 that is encoded in the genome of human.


ARF5_HUMAN ADP-ribosylation factor 5 (sprot)

An ADP-ribosylation factor 5 that is encoded in the genome of human.


GUC2D_HUMAN Retinal guanylyl cyclase 1 (sprot)

A retinal guanylyl cyclase 1 that is encoded in the genome of human.


GLTL6_HUMAN Polypeptide N-acetylgalactosaminyltransferase-like 6 (sprot)

A polypeptide N-acetylgalactosaminyltransferase-like 6 that is encoded in the genome of human.


ACSM3_HUMAN Acyl-coenzyme A synthetase ACSM3, mitochondrial (sprot)

An acyl-coenzyme A synthetase ACSM3, mitochondrial that is encoded in the genome of human.


ESCO2_HUMAN N-acetyltransferase ESCO2 (sprot)

An N-acetyltransferase ESCO2 that is encoded in the genome of human.


ESCO1_HUMAN N-acetyltransferase ESCO1 (sprot)

An N-acetyltransferase ESCO1 that is encoded in the genome of human.


GLT17_HUMAN Polypeptide N-acetylgalactosaminyltransferase 17 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 17 that is encoded in the genome of human.


ACSM6_HUMAN Acyl-coenzyme A synthetase ACSM6, mitochondrial (sprot)

An acyl-coenzyme A synthetase ACSM6, mitochondrial that is encoded in the genome of human.


GLT18_HUMAN Polypeptide N-acetylgalactosaminyltransferase 18 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 18 that is encoded in the genome of human.


GLTL5_HUMAN Inactive polypeptide N-acetylgalactosaminyltransferase-like protein 5 (sprot)

A polypeptide N-acetylgalactosaminyltransferase-like protein 5 that is encoded in the genome of human.


GALT5_HUMAN Polypeptide N-acetylgalactosaminyltransferase 5 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 5 that is encoded in the genome of human.


GALT7_HUMAN N-acetylgalactosaminyltransferase 7 (sprot)

An N-acetylgalactosaminyltransferase 7 that is encoded in the genome of human.


GLT10_HUMAN Polypeptide N-acetylgalactosaminyltransferase 10 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 10 that is encoded in the genome of human.