VGFR3_HUMAN Vascular endothelial growth factor receptor 3 (sprot)

A vascular endothelial growth factor receptor 3 that is encoded in the genome of human.


CDK2_HUMAN Cyclin-dependent kinase 2 (sprot)

A cyclin-dependent kinase 2 that is encoded in the genome of human.


DAPK3_HUMAN Death-associated protein kinase 3 (sprot)

A death-associated protein kinase 3 that is encoded in the genome of human.


MK10_HUMAN Mitogen-activated protein kinase 10 (sprot)

A mitogen-activated protein kinase 10 that is encoded in the genome of human.


KCC2D_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit delta (sprot)

A calcium/calmodulin-dependent protein kinase type II subunit delta that is encoded in the genome of human.


AAK1_HUMAN AP2-associated protein kinase 1 (sprot)

An AAK1 gene translation product (human), isoforms h1 and h2.


MET_HUMAN Hepatocyte growth factor receptor (sprot)

A hepatocyte growth factor receptor that is encoded in the genome of human.


ST17B_HUMAN Serine/threonine-protein kinase 17B (sprot)

A serine/threonine-protein kinase 17B that is encoded in the genome of human.


PLK4_HUMAN Serine/threonine-protein kinase PLK4 (sprot)

A serine/threonine-protein kinase PLK4 that is encoded in the genome of human.


AURKC_HUMAN Aurora kinase C (sprot)

An aurora kinase C that is encoded in the genome of human.


ST17A_HUMAN Serine/threonine-protein kinase 17A (sprot)

A serine/threonine-protein kinase 17A that is encoded in the genome of human.


ALK_HUMAN ALK tyrosine kinase receptor (sprot)

An ALK tyrosine kinase receptor that is encoded in the genome of human.


BMP2K_HUMAN BMP-2-inducible protein kinase (sprot)

A BMP-2-inducible protein kinase that is encoded in the genome of human.


EPHA7_HUMAN Ephrin type-A receptor 7 (sprot)

An ephrin type-A receptor 7 that is encoded in the genome of human.


MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 (sprot)

A MAP kinase-interacting serine/threonine-protein kinase 2 that is encoded in the genome of human.


ULK3_MOUSE Serine/threonine-protein kinase ULK3 (sprot)

A serine/threonine-protein kinase ULK3 that is encoded in the genome of mouse.


UFO_HUMAN Tyrosine-protein kinase receptor UFO (sprot)

A tyrosine-protein kinase receptor UFO that is encoded in the genome of human.


TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 (sprot)

A tyrosine-protein kinase receptor TYRO3 that is encoded in the genome of human.


KC1D_HUMAN Casein kinase I isoform delta (sprot)

A casein kinase I isoform delta that is encoded in the genome of human.


TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 (sprot)

A tyrosine-protein kinase receptor Tie-1 that is encoded in the genome of human.


MKNK1_HUMAN MAP kinase-interacting serine/threonine-protein kinase 1 (sprot)

A MAP kinase-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human.


LTK_HUMAN Leukocyte tyrosine kinase receptor (sprot)

A leukocyte tyrosine kinase receptor that is encoded in the genome of human.


MERTK_HUMAN Tyrosine-protein kinase Mer (sprot)

A tyrosine-protein kinase Mer that is encoded in the genome of human.


CTRO_HUMAN Citron Rho-interacting kinase (sprot)

A citron Rho-interacting kinase that is encoded in the genome of human.


COQ8B_HUMAN Atypical kinase COQ8B, mitochondrial (sprot)

An atypical kinase COQ8B, mitochondrial that is encoded in the genome of human.


MK04_HUMAN Mitogen-activated protein kinase 4 (sprot)

A mitogen-activated protein kinase 4 that is encoded in the genome of human.


E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase (sprot)

An interferon-induced, double-stranded RNA-activated protein kinase that is encoded in the genome of human.


KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 (sprot)

A ribosomal protein S6 kinase alpha-4 that is encoded in the genome of human.


DYRK2_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 2 (sprot)

A dual specificity tyrosine-phosphorylation-regulated kinase 2 that is encoded in the genome of human.


GRK4_HUMAN G protein-coupled receptor kinase 4 (sprot)

A G protein-coupled receptor kinase 4 that is encoded in the genome of human.


HIPK4_HUMAN Homeodomain-interacting protein kinase 4 (sprot)

A homeodomain-interacting protein kinase 4 that is encoded in the genome of human.


SRPK3_HUMAN SRSF protein kinase 3 (sprot)

An SRSF protein kinase 3 that is encoded in the genome of human.


RIPK4_HUMAN Receptor-interacting serine/threonine-protein kinase 4 (sprot)

A receptor-interacting serine/threonine-protein kinase 4 that is encoded in the genome of human.


PI42C_HUMAN Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (sprot)

A phosphatidylinositol 5-phosphate 4-kinase type-2 gamma that is encoded in the genome of human.


LRRK2_HUMAN Leucine-rich repeat serine/threonine-protein kinase 2 (sprot)

A leucine-rich repeat serine/threonine-protein kinase 2 that is encoded in the genome of human.


SO2B1_HUMAN Solute carrier organic anion transporter family member 2B1 (sprot)

A solute carrier organic anion transporter family member 2B1 that is encoded in the genome of human.


HEMH_HUMAN Ferrochelatase, mitochondrial (sprot)

A ferrochelatase, mitochondrial that is encoded in the genome of human.


BRAF_MOUSE Serine/threonine-protein kinase B-raf (sprot)

A B-Raf proto-oncogene serine/threonine-protein kinase that is encoded in the genome of mouse.


BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 (sprot)

A mitotic checkpoint serine/threonine-protein kinase BUB1 that is encoded in the genome of human.


ACD11_HUMAN Acyl-CoA dehydrogenase family member 11 (sprot)

An acyl-CoA dehydrogenase family member 11 that is encoded in the genome of human.


DCTP1_HUMAN dCTP pyrophosphatase 1 (sprot)

A dCTP pyrophosphatase 1 that is encoded in the genome of human.


CP1B1_HUMAN Cytochrome P450 1B1 (sprot)

A cytochrome P450 1B1 that is encoded in the genome of human.


Erythromycin propionate

A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.


ATP4A_HUMAN Potassium-transporting ATPase alpha chain 1 (sprot)

A potassium-transporting ATPase alpha chain 1 that is encoded in the genome of human.


ATP4B_HUMAN Potassium-transporting ATPase subunit beta (sprot)

A potassium-transporting ATPase subunit beta that is encoded in the genome of human.


GPER1_HUMAN G-protein coupled estrogen receptor 1 (sprot)

A G-protein coupled estrogen receptor 1 that is encoded in the genome of human.


ERR1_HUMAN Steroid hormone receptor ERR1 (sprot)

A steroid hormone receptor ERR1 that is encoded in the genome of human.


ESR1_RAT Estrogen receptor (sprot)

An estrogen receptor that is encoded in the genome of rat.


ESR2_RAT Estrogen receptor beta (sprot)

An estrogen receptor beta that is encoded in the genome of rat.


ESR2_MOUSE Estrogen receptor beta (sprot)

An estrogen receptor beta that is encoded in the genome of mouse.


ESR1_MOUSE Estrogen receptor (sprot)

An estrogen receptor that is encoded in the genome of mouse.


Estradiol benzoate

The 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position. Estradiol-17-beta is the most potent form of mammalian estrogenic steroids

A benzoate ester resulting from the formal condensation of benzoic acid with the phenolic hydroxy group of 17beta-estradiol.


Estramustine phosphate

A steroid phosphate which is the 17-O-phospho derivative of estramustine.


O51E2_HUMAN Olfactory receptor 51E2 (sprot)

An olfactory receptor 51E2 that is encoded in the genome of human.


MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 (sprot)

A dual specificity mitogen-activated protein kinase kinase 6 that is encoded in the genome of human.


GSTO1_HUMAN Glutathione S-transferase omega-1 (sprot)

A glutathione S-transferase omega-1 that is encoded in the genome of human.


EMBA_MYCTO Probable arabinosyltransferase A (sprot)


EMBB_MYCTO Probable arabinosyltransferase B (sprot)


EMBC_MYCTU Probable arabinosyltransferase C (sprot)


EMBA_MYCTU Probable arabinosyltransferase A (sprot)

A protein that is a translation product of the embA gene in Mycobacterium tuberculosis H37Rv.


INHA_MYCTU Enoyl-[acyl-carrier-protein] reductase [NADH] (sprot)


Ethisterone

17 alpha-Hydroxypregn-4-en-20-yn-3-one. A synthetic steroid hormone with progestational effects.

A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group. Ethisterone was the first orally active progestin and is a metabolite of danazol.


CAC1G_HUMAN Voltage-dependent T-type calcium channel subunit alpha-1G (sprot)

A voltage-dependent T-type calcium channel subunit alpha-1G that is encoded in the genome of human.


Ethoxzolamide

A carbonic anhydrase inhibitor used as diuretic and in glaucoma. It may cause hypokalemia.

A sulfonamide that is 1,3-benzothiazole-2-sulfonamide which is substituted by an ethoxy group at position 6. A carbonic anhydrase inhibitor, it has been used in the treatment of glaucoma, and as a diuretic.


Ethyl biscoumacetate

A coumarin that is used as an anticoagulant. It has actions similar to those of WARFARIN. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)


Ethylestrenol

An anabolic steroid with some progestational activity and little androgenic effect.

A 17beta-hydroxy steroid that is estrane containing a double bond between positions 4 and 5 and substituted by an ethyl group and a hydroxy group at the 17alpha and 17beta positions, respectively. It is an anabolic steroid that has little androgenic effect and only slight progestational activity. It has been used to promote growth in boys with delayed bone growth.


Etilefrine

A phenylephrine-related beta-1 adrenergic and alpha adrenergic agonist used as a cardiotonic and antihypotensive agent.


Etofylline

etophyllin appeared once in PubMed: Wien Med Wochenschr. 1986 May 15;136(9):213-8 as a combination drug with theophylline (spelt without e, theophllin)


C11B1_HUMAN Cytochrome P450 11B1, mitochondrial (sprot)

A cytochrome P450 11B that is a translation product of the CYP11B1 gene in human.


C11B2_HUMAN Cytochrome P450 11B2, mitochondrial (sprot)

A cytochrome P450 11B that is a translation product of the CYP11B2 gene in human.


MRP3_HUMAN ATP-binding cassette sub-family C member 3 (sprot)

An ATP-binding cassette sub-family C member 3 that is encoded in the genome of human.


GLP1R_HUMAN Glucagon-like peptide 1 receptor (sprot)

A glucagon-like peptide 1 receptor that is encoded in the genome of human.


GLP1R_RAT Glucagon-like peptide 1 receptor (sprot)

A glucagon-like peptide 1 receptor that is encoded in the genome of rat.


NPCL1_HUMAN NPC1-like intracellular cholesterol transporter 1 (sprot)

An NPC1-like intracellular cholesterol transporter 1 that is encoded in the genome of human.


NPCL1_RAT NPC1-like intracellular cholesterol transporter 1 (sprot)

An NPC1-like intracellular cholesterol transporter 1 that is encoded in the genome of rat.


Fadrozole

A selective aromatase inhibitor effective in the treatment of estrogen-dependent disease including breast cancer.


C11B2_MOUSE Cytochrome P450 11B2, mitochondrial (sprot)

A cytochrome P450 11B that is a translation product of the Cyp11b2 gene in mouse.


HS90A_HUMAN Heat shock protein HSP 90-alpha (sprot)

A heat shock protein HSP 90-alpha that is encoded in the genome of human.


KPCD_HUMAN Protein kinase C delta type (sprot)

A protein kinase C delta type that is encoded in the genome of human.


KPCE_HUMAN Protein kinase C epsilon type (sprot)

A protein kinase C epsilon that is encoded in the genome of human.


CLK1_HUMAN Dual specificity protein kinase CLK1 (sprot)

A dual specificity protein kinase CLK1 that is encoded in the genome of human.


KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 (sprot)

A ribosomal protein S6 kinase alpha-5 that is encoded in the genome of human.


CCL2_HUMAN C-C motif chemokine 2 (sprot)

A C-C motif chemokine 2 that is encoded in the genome of human.


CDK9_HUMAN Cyclin-dependent kinase 9 (sprot)

A cyclin-dependent kinase 9 that is encoded in the genome of human.


PKN2_HUMAN Serine/threonine-protein kinase N2 (sprot)

A serine/threonine-protein kinase N2 that is encoded in the genome of human.


MELK_HUMAN Maternal embryonic leucine zipper kinase (sprot)

A maternal embryonic leucine zipper kinase that is encoded in the genome of human.


LATS1_HUMAN Serine/threonine-protein kinase LATS1 (sprot)

A serine/threonine-protein kinase LATS1 that is encoded in the genome of human.


KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha (sprot)

A cAMP-dependent protein kinase catalytic subunit alpha that is encoded in the genome of human.


KPCD2_HUMAN Serine/threonine-protein kinase D2 (sprot)

A serine/threonine-protein kinase D2 that is encoded in the genome of human.


KPCD3_HUMAN Serine/threonine-protein kinase D3 (sprot)

A serine/threonine-protein kinase D3 that is encoded in the genome of human.


ROCK2_RAT Rho-associated protein kinase 2 (sprot)

A Rho-associated protein kinase 2 that is encoded in the genome of rat.


CDK13_HUMAN Cyclin-dependent kinase 13 (sprot)

A cyclin-dependent kinase 13 that is encoded in the genome of human.


PKN3_HUMAN Serine/threonine-protein kinase N3 (sprot)

A serine/threonine-protein kinase N3 that is encoded in the genome of human.


CDK12_HUMAN Cyclin-dependent kinase 12 (sprot)

A cyclin-dependent kinase 12 that is encoded in the genome of human.


ROCK1_HUMAN Rho-associated protein kinase 1 (sprot)

A Rho-associated protein kinase 1 that is encoded in the genome of human.


ROCK2_HUMAN Rho-associated protein kinase 2 (sprot)

A Rho-associated protein kinase 2 that is encoded in the genome of human.


CFTR_HUMAN Cystic fibrosis transmembrane conductance regulator (sprot)

A cystic fibrosis transmembrane conductance regulator that is encoded in the genome of human.


Fenbufen

an orally active nonsteroidal anti-inflammatory drug with analgesic and antipyretic activity


LUXR_ALIFS Transcriptional activator protein LuxR (sprot)


CASR_BOVIN Extracellular calcium-sensing receptor (sprot)

An extracellular calcium-sensing receptor that is encoded in the genome of cow.


SC5A8_HUMAN Sodium-coupled monocarboxylate transporter 1 (sprot)

A sodium-coupled monocarboxylate transporter 1 that is encoded in the genome of human.


OPRM_MOUSE Mu-type opioid receptor (sprot)

A mu-type opioid receptor that is encoded in the genome of mouse.


OPRD_MOUSE Delta-type opioid receptor (sprot)

A delta-type opioid receptor that is encoded in the genome of mouse.


SO1A2_HUMAN Solute carrier organic anion transporter family member 1A2 (sprot)

A solute carrier organic anion transporter family member 1A2 that is encoded in the genome of human.


3BHS1_HUMAN 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (sprot)

A 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 that is encoded in the genome of human.


S5A1_RAT 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (sprot)

A 3-oxo-5-alpha-steroid 4-dehydrogenase 1 that is encoded in the genome of rat.


S5A2_RAT 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (sprot)

A 3-oxo-5-alpha-steroid 4-dehydrogenase 2 that is encoded in the genome of rat.


KCND2_RAT Potassium voltage-gated channel subfamily D member 2 (sprot)

A protein that is a translation product of the Kcnd2 gene in rat.


Fleroxacin

A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.

A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.


CP51_TRYCC Sterol 14-alpha demethylase (sprot)

A protein that is a translation product of any of the 2 copies of the CYP51 gene in Trypanosoma cruzi strain CL Brener.


TYSY_CRYNB Thymidylate synthase (sprot)

A protein that is a translation product of the TMP1 gene in Cryptococcus neoformans var. neoformans B-3501A.


TYSY_CANAL Thymidylate synthase (sprot)

A thymidylate synthase that is encoded in the genome of Candida albicans SC5314.


HSP82_YEAST ATP-dependent molecular chaperone HSP82 (sprot)

A protein that is a translation product of the HSP82 gene in yeast.


KCNT2_HUMAN Potassium channel subfamily T member 2 (sprot)

A potassium channel subfamily T member 2 that is encoded in the genome of human.


TRPM5_HUMAN Transient receptor potential cation channel subfamily M member 5 (sprot)

A transient receptor potential cation channel subfamily M member 5 that is encoded in the genome of human.


TEAD4_HUMAN Transcriptional enhancer factor TEF-3 (sprot)

A transcriptional enhancer factor TEF-3 that is encoded in the genome of human.


T2R14_HUMAN Taste receptor type 2 member 14 (sprot)

A taste receptor type 2 member 14 that is encoded in the genome of human.


FACE2_HUMAN CAAX prenyl protease 2 (sprot)

A CAAX prenyl protease 2 that is encoded in the genome of human.


CAC1I_HUMAN Voltage-dependent T-type calcium channel subunit alpha-1I (sprot)

A voltage-dependent T-type calcium channel subunit alpha-1I that is encoded in the genome of human.


ANM1_HUMAN Protein arginine N-methyltransferase 1 (sprot)

A protein arginine N-methyltransferase 1 that is encoded in the genome of human.


KCNC1_RAT Potassium voltage-gated channel subfamily C member 1 (sprot)

A voltage-gated potassium channel KCNC1 that is encoded in the genome of rat.


KCNQ2_HUMAN Potassium voltage-gated channel subfamily KQT member 2 (sprot)

A voltage-gated potassium channel subunit KCNQ2 that is encoded in the genome of human.


KCNQ3_HUMAN Potassium voltage-gated channel subfamily KQT member 3 (sprot)

A voltage-gated potassium channel subunit KCNQ3 that is encoded in the genome of human.


Fluprednisolone

A synthetic glucocorticoid with anti-inflammatory properties.


PA24A_HUMAN Cytosolic phospholipase A2 (sprot)

A cytosolic phospholipase A2 that is encoded in the genome of human.


Gamma-Aminobutyric Acid

The most common inhibitory neurotransmitter in the central nervous system.

A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.


Flutrimazole

An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts.


SIR6_HUMAN NAD-dependent protein deacylase sirtuin-6 (sprot)

An NAD-dependent protein deacylase sirtuin-6 that is encoded in the genome of human.


ADH1B_HUMAN All-trans-retinol dehydrogenase [NAD(+)] ADH1B (sprot)

An all-trans-retinol dehydrogenase [NAD(+)] ADH1B that is encoded in the genome of human.


ADH1G_HUMAN Alcohol dehydrogenase 1C (sprot)

An alcohol dehydrogenase 1C that is encoded in the genome of human.


ADH1A_HUMAN Alcohol dehydrogenase 1A (sprot)

An alcohol dehydrogenase 1A that is encoded in the genome of human.


ANT3_HUMAN Antithrombin-III (sprot)

An antithrombin-III that is encoded in the genome of human.


DPOL_HCMVA DNA polymerase catalytic subunit (sprot)


MURA1_ENTFA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 (sprot)


MURA2_ENTFA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 (sprot)


MURA_ECOLI UDP-N-acetylglucosamine 1-carboxyvinyltransferase (sprot)

A UDP-N-acetylglucosamine 1-carboxyvinyltransferase that is encoded in the genome of Escherichia coli K-12.


MURA_PSEAE UDP-N-acetylglucosamine 1-carboxyvinyltransferase (sprot)


D-Fructose

A monosaccharide in sweet fruits and honey that is soluble in water, alcohol, or ether. It is used as a preservative and an intravenous infusion in parenteral feeding.

A ketohexose that is an isomer of glucose.


HYES_HUMAN Bifunctional epoxide hydrolase 2 (sprot)

An epoxide hydrolase 2 that is encoded in the genome of human.


ACPS_BACSU Holo-[acyl-carrier-protein] synthase (sprot)


SC6A1_RAT Sodium- and chloride-dependent GABA transporter 1 (sprot)

A sodium- and chloride-dependent GABA transporter 1 that is encoded in the genome of rat.


SC6A1_MOUSE Sodium- and chloride-dependent GABA transporter 1 (sprot)

A sodium- and chloride-dependent GABA transporter 1 that is encoded in the genome of mouse.


GBRR1_HUMAN Gamma-aminobutyric acid receptor subunit rho-1 (sprot)

A gamma-aminobutyric acid receptor subunit rho-1 that is encoded in the genome of human.


S6A11_HUMAN Sodium- and chloride-dependent GABA transporter 3 (sprot)

A sodium- and chloride-dependent GABA transporter 3 that is encoded in the genome of human.


S6A12_HUMAN Sodium- and chloride-dependent betaine transporter (sprot)

A sodium- and chloride-dependent betaine transporter that is encoded in the genome of human.


S6A11_MOUSE Sodium- and chloride-dependent GABA transporter 3 (sprot)

A sodium- and chloride-dependent GABA transporter 3 that is encoded in the genome of mouse.


S6A13_RAT Sodium- and chloride-dependent GABA transporter 2 (sprot)

A sodium- and chloride-dependent GABA transporter 2 that is encoded in the genome of rat.


S6A13_MOUSE Sodium- and chloride-dependent GABA transporter 2 (sprot)

A sodium- and chloride-dependent GABA transporter 2 that is encoded in the genome of mouse.


GPVI_HUMAN Platelet glycoprotein VI (sprot)

A platelet glycoprotein VI that is encoded in the genome of human.


S6A13_HUMAN Sodium- and chloride-dependent GABA transporter 2 (sprot)

A sodium- and chloride-dependent GABA transporter 2 that is encoded in the genome of human.


LAT1_HUMAN Large neutral amino acids transporter small subunit 1 (sprot)

A large neutral amino acids transporter small subunit 1 that is encoded in the genome of human.


KCNQ5_HUMAN Potassium voltage-gated channel subfamily KQT member 5 (sprot)

A voltage-gated potassium channel subunit KCNQ5 that is encoded in the genome of human.


CA2D1_MOUSE Voltage-dependent calcium channel subunit alpha-2/delta-1 (sprot)

A voltage-dependent calcium channel subunit alpha-2/delta-1 that is encoded in the genome of mouse.


O77773_PIG Calcium voltage-gated channel auxiliary subunit alpha2delta 1 (trembl)


CA2D2_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-2 (sprot)

A voltage-dependent calcium channel subunit alpha-2/delta-2 that is encoded in the genome of human.


alpha-D-GALACTOSE

An aldohexose that occurs naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins. Deficiency of galactosyl-1-phosphate uridyltransferase (GALACTOSE-1-PHOSPHATE URIDYL-TRANSFERASE DEFICIENCY DISEASE) causes an error in galactose metabolism called GALACTOSEMIA, resulting in elevations of galactose in the blood.

D-Galactopyranose having alpha-configuration at the anomeric centre.


Triethylgallamine

A synthetic nondepolarizing blocking drug. The actions of gallamine triethiodide are similar to those of TUBOCURARINE, but this agent blocks the cardiac vagus and may cause sinus tachycardia and, occasionally, hypertension and increased cardiac output. It should be used cautiously in patients at risk from increased heart rate but may be preferred for patients with bradycardia. (From AMA Drug Evaluations Annual, 1992, p198)


Gallopamil

Coronary vasodilator that is an analog of iproveratril (VERAPAMIL) with one more methoxy group on the benzene ring.


gamma-Linolenic acid

An omega-6 fatty acid produced in the body as the delta 6-desaturase metabolite of linoleic acid. It is converted to dihomo-gamma-linolenic acid, a biosynthetic precursor of monoenoic prostaglandins such as PGE1. (From Merck Index, 11th ed)

A C18, omega-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.


FFAR1_HUMAN Free fatty acid receptor 1 (sprot)

A free fatty acid receptor 1 that is encoded in the genome of human.


TF_HUMAN Tissue factor (sprot)

A tissue factor that is encoded in the genome of human.


GRM1_HUMAN Metabotropic glutamate receptor 1 (sprot)

A metabotropic glutamate receptor 1 that is encoded in the genome of human.


GRM5_HUMAN Metabotropic glutamate receptor 5 (sprot)

A metabotropic glutamate receptor 5 that is encoded in the genome of human.


SCAF_HHV11 Capsid scaffolding protein (sprot)


PARC_STRPN DNA topoisomerase 4 subunit A (sprot)

A protein that is a translation product of the parC gene in Streptococcus pneumoniae TIGR4.


PARE_STRPN DNA topoisomerase 4 subunit B (sprot)

A protein that is a translation product of the parE gene in Streptococcus pneumoniae TIGR4.


GYRA_STRPN DNA gyrase subunit A (sprot)

A DNA gyrase subunit A that is encoded in the genome of Streptococcus pneumoniae TIGR4.


GYRB_STRPN DNA gyrase subunit B (sprot)

A DNA gyrase subunit B that is encoded in the genome of Streptococcus pneumoniae TIGR4.


PHKG2_HUMAN Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (sprot)

A phosphorylase b kinase gamma catalytic chain, liver/testis isoform that is encoded in the genome of human.


PHKG1_HUMAN Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform (sprot)

A phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform that is encoded in the genome of human.


CDK7_HUMAN Cyclin-dependent kinase 7 (sprot)

A cyclin-dependent kinase 7 that is encoded in the genome of human.


KPCD1_HUMAN Serine/threonine-protein kinase D1 (sprot)

A serine/threonine-protein kinase D1 that is encoded in the genome of human.


DCLK3_HUMAN Serine/threonine-protein kinase DCLK3 (sprot)

A serine/threonine-protein kinase DCLK3 that is encoded in the genome of human.


NUAK2_HUMAN NUAK family SNF1-like kinase 2 (sprot)

A NUAK family SNF1-like kinase 2 that is encoded in the genome of human.


IRAK3_HUMAN Interleukin-1 receptor-associated kinase 3 (sprot)

An interleukin-1 receptor-associated kinase 3 that is encoded in the genome of human.


PIM3_HUMAN Serine/threonine-protein kinase pim-3 (sprot)

A serine/threonine-protein kinase Pim-3 that is encoded in the genome of human.


MK06_HUMAN Mitogen-activated protein kinase 6 (sprot)

A mitogen-activated protein kinase 6 that is encoded in the genome of human.


IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 (sprot)

An interleukin-1 receptor-associated kinase 4 that is encoded in the genome of human.


CHK2_HUMAN Serine/threonine-protein kinase Chk2 (sprot)

A serine/threonine-protein kinase Chk2 that is encoded in the genome of human.


IRAK1_HUMAN Interleukin-1 receptor-associated kinase 1 (sprot)

An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of human.


RIPK3_HUMAN Receptor-interacting serine/threonine-protein kinase 3 (sprot)

A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human.


ACD10_HUMAN Acyl-CoA dehydrogenase family member 10 (sprot)

An acyl-CoA dehydrogenase family member 10 that is encoded in the genome of human.


KCY_HUMAN UMP-CMP kinase (sprot)

A UMP-CMP kinase that is encoded in the genome of human.


CP2C8_HUMAN Cytochrome P450 2C8 (sprot)

A cytochrome P450 2C8 that is encoded in the genome of human.


Gestodene

synthetic steroid with progestational activity; RN given refers to (17alpha)-isomer


Gestrinone

A non-estrogenic contraceptive which is a weak progestin with strong anti-progesterone properties. It is effective if used once a week orally or can also be used in intravaginal devices.


DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP(+)] (sprot)

A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of human.


Glafenine

An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.

A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.


ABCC9_HUMAN ATP-binding cassette sub-family C member 9 (sprot)

An ATP-binding cassette sub-family C member 9 that is encoded in the genome of human.


GRIK1_HUMAN Glutamate receptor ionotropic, kainate 1 (sprot)

A glutamate receptor ionotropic, kainate 1 that is encoded in the genome of human.


DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial (sprot)

A glutamate dehydrogenase 1, mitochondrial that is encoded in the genome of human.


DHE4_HUMAN Glutamate dehydrogenase 2, mitochondrial (sprot)

A glutamate dehydrogenase 2, mitochondrial that is encoded in the genome of human.


GRIK5_HUMAN Glutamate receptor ionotropic, kainate 5 (sprot)

A glutamate receptor ionotropic, kainate 5 that is encoded in the genome of human.


GRM4_HUMAN Metabotropic glutamate receptor 4 (sprot)

A metabotropic glutamate receptor 4 that is encoded in the genome of human.


GRIK2_HUMAN Glutamate receptor ionotropic, kainate 2 (sprot)

A glutamate receptor ionotropic, kainate 2 that is encoded in the genome of human.


GRIK3_HUMAN Glutamate receptor ionotropic, kainate 3 (sprot)

A glutamate receptor ionotropic, kainate 3 that is encoded in the genome of human.


GRM7_HUMAN Metabotropic glutamate receptor 7 (sprot)

A metabotropic glutamate receptor 7 that is encoded in the genome of human.


GRM6_HUMAN Metabotropic glutamate receptor 6 (sprot)

A metabotropic glutamate receptor 6 that is encoded in the genome of human.


GRM2_HUMAN Metabotropic glutamate receptor 2 (sprot)

A metabotropic glutamate receptor 2 that is encoded in the genome of human.


EAA1_HUMAN Excitatory amino acid transporter 1 (sprot)

An excitatory amino acid transporter 1 that is encoded in the genome of human.


EAA2_HUMAN Excitatory amino acid transporter 2 (sprot)

An excitatory amino acid transporter 2 that is encoded in the genome of human.


EAA3_HUMAN Excitatory amino acid transporter 3 (sprot)

An excitatory amino acid transporter 3 that is encoded in the genome of human.


GRIK4_HUMAN Glutamate receptor ionotropic, kainate 4 (sprot)

A glutamate receptor ionotropic, kainate 4 that is encoded in the genome of human.


GRM3_HUMAN Metabotropic glutamate receptor 3 (sprot)

A metabotropic glutamate receptor 3 that is encoded in the genome of human.


GRM8_HUMAN Metabotropic glutamate receptor 8 (sprot)

A metabotropic glutamate receptor 8 that is encoded in the genome of human.


GRIK2_RAT Glutamate receptor ionotropic, kainate 2 (sprot)

A glutamate receptor ionotropic, kainate 2 that is encoded in the genome of rat.


GRIK1_RAT Glutamate receptor ionotropic, kainate 1 (sprot)

A glutamate receptor ionotropic, kainate 1 that is encoded in the genome of rat.


GRM4_RAT Metabotropic glutamate receptor 4 (sprot)

A metabotropic glutamate receptor 4 that is encoded in the genome of rat.


GRM6_RAT Metabotropic glutamate receptor 6 (sprot)

A metabotropic glutamate receptor 6 that is encoded in the genome of rat.


GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (sprot)

A glutamate receptor ionotropic, kainate 3 that is encoded in the genome of rat.


MURI_LIMFE Glutamate racemase (sprot)

A protein that is a translation product of the murI gene in Limosilactobacillus fermentum.


GRM8_RAT Metabotropic glutamate receptor 8 (sprot)

A metabotropic glutamate receptor 8 that is encoded in the genome of rat.


GRM8_MOUSE Metabotropic glutamate receptor 8 (sprot)

A metabotropic glutamate receptor 8 that is encoded in the genome of mouse.


GRM1_RAT Metabotropic glutamate receptor 1 (sprot)

A metabotropic glutamate receptor 1 that is encoded in the genome of rat.


GRM2_RAT Metabotropic glutamate receptor 2 (sprot)

A metabotropic glutamate receptor 2 that is encoded in the genome of rat.


GRM3_RAT Metabotropic glutamate receptor 3 (sprot)

A metabotropic glutamate receptor 3 that is encoded in the genome of rat.


EAA4_RAT Excitatory amino acid transporter 4 (sprot)

An excitatory amino acid transporter 4 that is encoded in the genome of rat.


Q9Z1J7_RAT Amino acid transporter (trembl)


GSTK1_HUMAN Glutathione S-transferase kappa 1 (sprot)

A glutathione S-transferase kappa 1 that is encoded in the genome of human.


NLRP3_HUMAN NACHT, LRR and PYD domains-containing protein 3 (sprot)

A NACHT, LRR and PYD domains-containing protein 3 that is encoded in the genome of human.


NLRP3_MOUSE NACHT, LRR and PYD domains-containing protein 3 (sprot)

A NACHT, LRR and PYD domains-containing protein 3 that is encoded in the genome of mouse.


ABCC8_RAT ATP-binding cassette sub-family C member 8 (sprot)

An ATP-binding cassette sub-family C member 8 that is encoded in the genome of rat.


TRPM4_RAT Transient receptor potential cation channel subfamily M member 4 (sprot)

A transient receptor potential cation channel subfamily M member 4 that is encoded in the genome of rat.


SC6A9_HUMAN Sodium- and chloride-dependent glycine transporter 1 (sprot)

A sodium- and chloride-dependent glycine transporter 1 that is encoded in the genome of human.


Glycyrrhizin

A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.

A  triterpenoid saponin that is the  glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.


BGLR_RAT Beta-glucuronidase (sprot)

A beta-glucuronidase that is encoded in the genome of rat.


HMGB1_HUMAN High mobility group protein B1 (sprot)

A high mobility group protein B1 that is encoded in the genome of human.


BGLR_ECOLI Beta-glucuronidase (sprot)

A beta-glucuronidase that is encoded in the genome of Escherichia coli K-12.


Gossypol

A dimeric sesquiterpene found in cottonseed (GOSSYPIUM). The (-) isomer is active as a male contraceptive (CONTRACEPTIVE AGENTS, MALE) whereas toxic symptoms are associated with the (+) isomer.


ASPH_HUMAN Aspartyl/asparaginyl beta-hydroxylase (sprot)

An aspartyl/asparaginyl beta-hydroxylase that is encoded in the genome of human.


B2CL1_HUMAN Bcl-2-like protein 1 (sprot)

A Bcl-2-like protein 1 that is encoded in the genome of human.


MDHM_PIG Malate dehydrogenase, mitochondrial (sprot)


Q0PJ46_PLAFA L-lactate dehydrogenase (trembl)


Q6VVP7_PLAFA L-lactate dehydrogenase (trembl)


MDHC_PIG Malate dehydrogenase, cytoplasmic (sprot)

A malate dehydrogenase, cytoplasmic that is encoded in the genome of pig.


B2CL2_HUMAN Bcl-2-like protein 2 (sprot)

A protein that is a translation product of any of the following genes in human: BCL2L2, or a readthrough of the BCL2L2-PABPN1 genes.


KIF11_HUMAN Kinesin-like protein KIF11 (sprot)

A kinesin-like protein KIF11 that is encoded in the genome of human.


3MG_HUMAN DNA-3-methyladenine glycosylase (sprot)

A DNA-3-methyladenine glycosylase that is encoded in the genome of human.


LDHB_HUMAN L-lactate dehydrogenase B chain (sprot)

An L-lactate dehydrogenase B chain that is encoded in the genome of human.


F2SG63_TRIRC Tubulin alpha chain (trembl)


F2SZ02_TRIRC Tubulin alpha chain (trembl)


F2SZD3_TRIRC Tubulin beta chain (trembl)


KCNA2_HUMAN Potassium voltage-gated channel subfamily A member 2 (sprot)

A voltage-gated potassium channel subunit KCNA2 that is encoded in the genome of human.


KCNA6_HUMAN Potassium voltage-gated channel subfamily A member 6 (sprot)

A voltage-gated potassium channel subunit KCNA6 that is encoded in the genome of human.


KCNA4_HUMAN Potassium voltage-gated channel subfamily A member 4 (sprot)

A voltage-gated potassium channel alpha subunit KCNA4 that is encoded in the genome of human.


KCNC1_HUMAN Potassium voltage-gated channel subfamily C member 1 (sprot)

A voltage-gated potassium channel KCNC1 that is encoded in the genome of human.


KCNQ1_HUMAN Potassium voltage-gated channel subfamily KQT member 1 (sprot)

A voltage-gated potassium channel subunit KCNQ1 that is encoded in the genome of human.


KCNC4_HUMAN Potassium voltage-gated channel subfamily C member 4 (sprot)

A voltage-gated potassium channel KCNC4 that is encoded in the genome of human.


KCNC3_HUMAN Potassium voltage-gated channel subfamily C member 3 (sprot)

A voltage-gated potassium channel KCNC3 that is encoded in the genome of human.


KCNB1_HUMAN Potassium voltage-gated channel subfamily B member 1 (sprot)

A voltage-gated potassium channel KCNB1 that is encoded in the genome of human.


KCA10_HUMAN Potassium voltage-gated channel subfamily A member 10 (sprot)

A voltage-gated potassium channel subunit KCNA10 that is encoded in the genome of human.


KCNV1_HUMAN Potassium voltage-gated channel subfamily V member 1 (sprot)

A voltage-gated potassium channel KCNV1 that is encoded in the genome of human.


KCNH5_HUMAN Potassium voltage-gated channel subfamily H member 5 (sprot)

A voltage-gated potassium channel KCNH5 that is encoded in the genome of human.


KCNG3_HUMAN Potassium voltage-gated channel subfamily G member 3 (sprot)

A voltage-gated potassium channel subfamily G member 3 that is encoded in the genome of human.


KCNG4_HUMAN Potassium voltage-gated channel subfamily G member 4 (sprot)

A voltage-gated potassium channel subfamily G member 4 that is encoded in the genome of human.


KCNV2_HUMAN Potassium voltage-gated channel subfamily V member 2 (sprot)

A voltage-gated potassium channel KCNV2 that is encoded in the genome of human.


KCNB2_HUMAN Potassium voltage-gated channel subfamily B member 2 (sprot)

A voltage-gated potassium channel KCNB2 that is encoded in the genome of human.


KCNS1_HUMAN Potassium voltage-gated channel subfamily S member 1 (sprot)

A voltage-gated potassium channel KCNS1 that is encoded in the genome of human.


KCNH8_HUMAN Potassium voltage-gated channel subfamily H member 8 (sprot)

A voltage-gated potassium channel KCNH8 that is encoded in the genome of human.


KCNC2_HUMAN Potassium voltage-gated channel subfamily C member 2 (sprot)

A voltage-gated potassium channel KCNC2 that is encoded in the genome of human.


KCNS3_HUMAN Potassium voltage-gated channel subfamily S member 3 (sprot)

A voltage-gated potassium channel KCNS3 that is encoded in the genome of human.


KCNH6_HUMAN Potassium voltage-gated channel subfamily H member 6 (sprot)

A voltage-gated potassium channel KCNH6 that is encoded in the genome of human.


KCNF1_HUMAN Potassium voltage-gated channel subfamily F member 1 (sprot)

A voltage-gated potassium channel KCNF1 that is encoded in the genome of human.


KCNH7_HUMAN Potassium voltage-gated channel subfamily H member 7 (sprot)

A voltage-gated potassium channel KCNH7 that is encoded in the genome of human.


KCND1_HUMAN Potassium voltage-gated channel subfamily D member 1 (sprot)

A voltage-gated potassium channel KCND1 that is encoded in the genome of human.


KCND2_HUMAN Potassium voltage-gated channel subfamily D member 2 (sprot)

A voltage-gated potassium channel KCND2 that is encoded in the genome of human.


KCNG1_HUMAN Potassium voltage-gated channel subfamily G member 1 (sprot)

A voltage-gated potassium channel KCNG1 that is encoded in the genome of human.


KCNG2_HUMAN Potassium voltage-gated channel subfamily G member 2 (sprot)

A voltage-gated potassium channel KCNG2 that is encoded in the genome of human.


KCNH3_HUMAN Potassium voltage-gated channel subfamily H member 3 (sprot)

A voltage-gated potassium channel KCNH3 that is encoded in the genome of human.


KCNS2_HUMAN Potassium voltage-gated channel subfamily S member 2 (sprot)

A voltage-gated potassium channel KCNS2 that is encoded in the genome of human.


KCNH4_HUMAN Potassium voltage-gated channel subfamily H member 4 (sprot)

A voltage-gated potassium channel KCNH4 that is encoded in the genome of human.


Q4U254_9ENTO Genome polyprotein (Fragment) (trembl)


5HT2A_PIG 5-hydroxytryptamine receptor 2A (sprot)

A 5-hydroxytryptamine receptor 2A that is encoded in the genome of pig.


VACHT_RAT Vesicular acetylcholine transporter (sprot)

A vesicular acetylcholine transporter that is encoded in the genome of rat.


AP2S1_RAT AP-2 complex subunit sigma (sprot)

An AP-2 complex subunit sigma that is encoded in the genome of rat.


ZN664_CAVPO Zinc finger protein 664 (sprot)


SPIKE_SARS2 Spike glycoprotein (sprot)

A protein that is a translation product of the S gene in SARS-CoV-2.


Hesperetin

A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position.


DPP4_HUMAN Dipeptidyl peptidase 4 (sprot)

A dipeptidyl peptidase 4 that is encoded in the genome of human.


GSK3B_HUMAN Glycogen synthase kinase-3 beta (sprot)

A glycogen synthase kinase-3 beta that is encoded in the genome of human.


KDM1A_HUMAN Lysine-specific histone demethylase 1A (sprot)

A lysine-specific histone demethylase 1A that is encoded in the genome of human.


Q54618_STREE Penicillin binding protein 2B (trembl)


Q75Y37_STREE serine-type D-Ala-D-Ala carboxypeptidase (trembl)


Q75Y54_STREE Penicillin-binding protein 2X (trembl)


Q75YD8_STREE PBP1A family penicillin-binding protein (trembl)


Q75YK0_STREE Penicillin-binding protein (trembl)


Q9RET4_STREE Penicillin-binding protein 1A (trembl)


DLD_ECOLI Quinone-dependent D-lactate dehydrogenase (sprot)

A quinone-dependent D-lactate dehydrogenase that is encoded in the genome of Escherichia coli K-12.


FABI_ECOLI Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (sprot)

An enoyl-[acyl-carrier-protein] reductase [NADH] FabI that is encoded in the genome of Escherichia coli K-12.


MIF_HUMAN Macrophage migration inhibitory factor (sprot)

A macrophage migration inhibitory factor that is encoded in the genome of human.


NAPEP_HUMAN N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (sprot)

An N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D that is encoded in the genome of human.


NAPEP_MOUSE N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D (sprot)

An N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D that is encoded in the genome of mouse.


Hexafluronium

curarimimetic agent for use with succinylcholine; muscle relaxant; structure; RN given refers to parent cpd


Hexamethonium

A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.


ACHB_TETCF Acetylcholine receptor subunit beta (sprot)


ACHG_TETCF Acetylcholine receptor subunit gamma (sprot)


ACHA6_HUMAN Neuronal acetylcholine receptor subunit alpha-6 (sprot)

A neuronal acetylcholine receptor subunit alpha-6 that is encoded in the genome of human.


meso-Hexestrol

A synthetic estrogen that has been used as a hormonal antineoplastic agent.


Hexobarbital

A barbiturate that is effective as a hypnotic and sedative.

A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.


Hexobendine

A potent vasoactive agent that dilates cerebral and coronary arteries, but slightly constricts femoral arteries, without any effects on heart rate, blood pressure or cardiac output.


TYRO_HUMAN Tyrosinase (sprot)

A tyrosinase that is encoded in the genome of human.


HRH3_MOUSE Histamine H3 receptor (sprot)

A histamine H3 receptor that is encoded in the genome of mouse.


HRH3_CAVPO Histamine H3 receptor (sprot)


Q91ZY3_CAVPO Histamine H4 receptor (trembl)


Hycanthone

Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.

A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.


APEX1_HUMAN DNA-(apurinic or apyrimidinic site) endonuclease (sprot)

A DNA-(apurinic or apyrimidinic site) endonuclease that is encoded in the genome of human.


DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (sprot)

A DNA (cytosine-5)-methyltransferase 3B that is encoded in the genome of human.


PERL_BOVIN Lactoperoxidase (sprot)

A lactoperoxidase that is encoded in the genome of cow.


RYR2_RAT Ryanodine receptor 2 (sprot)

A ryanodine receptor 2 that is encoded in the genome of rat.


GCR_MOUSE Glucocorticoid receptor (sprot)

A glucocorticoid receptor that is encoded in the genome of mouse.


HBA_HUMAN Hemoglobin subunit alpha (sprot)

A hemoglobin subunit alpha that is encoded in the genome of human.


TLR7_HUMAN Toll-like receptor 7 (sprot)

A Toll-like receptor 7 that is encoded in the genome of human.


Hydroxystilbamidinum

minor descriptor (63-86); on-line & INDEX MEDICUS search STILBAMIDINES (66-86); RN given refers to parent cpd


Hymecromone

A coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID.

A hydroxycoumarin that is umbelliferone substituted by a methyl group at position 4.


GGPPS_HUMAN Geranylgeranyl pyrophosphate synthase (sprot)

A geranylgeranyl pyrophosphate synthase that is encoded in the genome of human.


ALBU_BOVIN Albumin (sprot)

An albumin that is encoded in the genome of cow.


DHRS9_RAT Dehydrogenase/reductase SDR family member 9 (sprot)

A dehydrogenase/reductase SDR family member 9 that is encoded in the genome of rat.


Ibuproxam

A hydroxamic acid obtained by formal condensation of the carboxy group of ibuprofen with the amino group of hydroxylamine. Used for treatment of pain and inflammation associated with musculoskeletal and joint disorders.


DGAT1_HUMAN Diacylglycerol O-acyltransferase 1 (sprot)

A diacylglycerol O-acyltransferase 1 that is encoded in the genome of human.


T1VXA1_SCHMA NAD-dependent protein deacetylase (trembl)


Ifenprodil

NMDA receptor antagonist; RN given refers to parent cpd without isomeric designation; structure


A 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase that is encoded in the genome of guinea pig.


INSR_HUMAN Insulin receptor (sprot)

An insulin receptor that is encoded in the genome of human.


MK08_HUMAN Mitogen-activated protein kinase 8 (sprot)

A mitogen-activated protein kinase 8 that is encoded in the genome of human.


CLK4_HUMAN Dual specificity protein kinase CLK4 (sprot)

A dual specificity protein kinase CLK4 that is encoded in the genome of human.


SYK_HUMAN Lysine--tRNA ligase (sprot)

A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of human.


CSK22_HUMAN Casein kinase II subunit alpha' (sprot)

A casein kinase II subunit alpha' that is encoded in the genome of human.


CDK19_HUMAN Cyclin-dependent kinase 19 (sprot)

A cyclin-dependent kinase 19 that is encoded in the genome of human.


ABL1_MOUSE Tyrosine-protein kinase ABL1 (sprot)

A tyrosine-protein kinase ABL1 that is encoded in the genome of mouse.


PGFRB_RAT Platelet-derived growth factor receptor beta (sprot)

A beta-type platelet-derived growth factor receptor that is encoded in the genome of rat.


DDX3X_HUMAN ATP-dependent RNA helicase DDX3X (sprot)

An ATP-dependent RNA helicase DDX3X that is encoded in the genome of human.


8ODP_HUMAN Oxidized purine nucleoside triphosphate hydrolase (sprot)

An oxidized purine nucleoside triphosphate hydrolase that is encoded in the genome of human.


Q8MTZ4_9TRYP H(+)-exporting diphosphatase (trembl)


Indalpine

selective 5-hydroxytryptamine uptake inhibitor; RN given refers to parent cpd


INDISETRON

an anti-emetic agent, indisetron hydrochloride was developed in Japan


DHRS9_HUMAN Dehydrogenase/reductase SDR family member 9 (sprot)

A dehydrogenase/reductase SDR family member 9 that is encoded in the genome of human.


Indoramin

An alpha-1 adrenergic antagonist that is commonly used as an antihypertensive agent.


NOS2_MOUSE Nitric oxide synthase, inducible (sprot)

A nitric oxide synthase, inducible that is encoded in the genome of mouse.


AK1C4_HUMAN Aldo-keto reductase family 1 member C4 (sprot)

An aldo-keto reductase family 1 member C4 that is encoded in the genome of human.


Indoprofen

A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p21)

A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.


LUCI_PHOPY Luciferin 4-monooxygenase (sprot)


Iprindole

A tricyclic antidepressant that has actions and uses similar to those of AMITRIPTYLINE, but has only weak antimuscarinic and sedative effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p257)


Isoetharine

Adrenergic beta-2 agonist used as bronchodilator for emphysema, bronchitis and asthma.


Diisopropyl fluorophosphate

A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.


EST1_PIG Liver carboxylesterase (sprot)

A protein that is a translation product of the CES1 gene in pig.


DYR_MYCTU Dihydrofolate reductase (sprot)


ADRB2_MESAU Beta-2 adrenergic receptor (sprot)

A protein that is a translation product of the ADRB2 gene in Mesocricetus auratus.


T2R38_HUMAN Taste receptor type 2 member 38 (sprot)

A taste receptor type 2 member 38 that is encoded in the genome of human.


T2R39_HUMAN Taste receptor type 2 member 39 (sprot)

A taste receptor type 2 member 39/139 that is encoded in the genome of human.


T2R40_HUMAN Taste receptor type 2 member 40 (sprot)

A taste receptor type 2 member 40 that is encoded in the genome of human.


T2R41_HUMAN Taste receptor type 2 member 41 (sprot)

A taste receptor type 2 member 41 that is encoded in the genome of human.


T2R43_HUMAN Taste receptor type 2 member 43 (sprot)

A taste receptor type 2 member 43 that is encoded in the genome of human.


T2R31_HUMAN Taste receptor type 2 member 31 (sprot)

A taste receptor type 2 member 31 that is encoded in the genome of human.


T2R45_HUMAN Taste receptor type 2 member 45 (sprot)

A taste receptor type 2 member 45 that is encoded in the genome of human.


T2R30_HUMAN Taste receptor type 2 member 30 (sprot)

A taste receptor type 2 member 30 that is encoded in the genome of human.


T2R19_HUMAN Taste receptor type 2 member 19 (sprot)

A taste receptor type 2 member 19 that is encoded in the genome of human.


T2R20_HUMAN Taste receptor type 2 member 20 (sprot)

A taste receptor type 2 member 20 that is encoded in the genome of human.


T2R50_HUMAN Taste receptor type 2 member 50 (sprot)

A taste receptor type 2 member 50 that is encoded in the genome of human.


T2R60_HUMAN Taste receptor type 2 member 60 (sprot)

A taste receptor type 2 member 60/135 that is encoded in the genome of human.


T2R42_HUMAN Taste receptor type 2 member 42 (sprot)

A taste receptor type 2 member 42 that is encoded in the genome of human.


T2R16_HUMAN Taste receptor type 2 member 16 (sprot)

A taste receptor type 2 member 16 that is encoded in the genome of human.


T2R13_HUMAN Taste receptor type 2 member 13 (sprot)

A taste receptor type 2 member 13 that is encoded in the genome of human.


T2R10_HUMAN Taste receptor type 2 member 10 (sprot)

A taste receptor type 2 member 10 that is encoded in the genome of human.


TA2R9_HUMAN Taste receptor type 2 member 9 (sprot)

A taste receptor type 2 member 9 that is encoded in the genome of human.


TA2R8_HUMAN Taste receptor type 2 member 8 (sprot)

A taste receptor type 2 member 8 that is encoded in the genome of human.


TA2R7_HUMAN Taste receptor type 2 member 7 (sprot)

A taste receptor type 2 member 7 that is encoded in the genome of human.


TA2R5_HUMAN Taste receptor type 2 member 5 (sprot)

A taste receptor type 2 member 5 that is encoded in the genome of human.


TA2R4_HUMAN Taste receptor type 2 member 4 (sprot)

A taste receptor type 2 member 4 that is encoded in the genome of human.


TA2R3_HUMAN Taste receptor type 2 member 3 (sprot)

A taste receptor type 2 member 3 that is encoded in the genome of human.


TA2R1_HUMAN Taste receptor type 2 member 1 (sprot)

A taste receptor type 2 member 1/119 that is encoded in the genome of human.


GCYA2_HUMAN Guanylate cyclase soluble subunit alpha-2 (sprot)

A guanylate cyclase soluble subunit alpha-2 that is encoded in the genome of human.


GCYA1_HUMAN Guanylate cyclase soluble subunit alpha-1 (sprot)

A guanylate cyclase soluble subunit alpha-1 that is encoded in the genome of human.


GCYB2_HUMAN Guanylate cyclase soluble subunit beta-2 (sprot)

A guanylate cyclase soluble subunit beta-2 that is encoded in the genome of human.


GCYB1_HUMAN Guanylate cyclase soluble subunit beta-1 (sprot)

A guanylate cyclase soluble subunit beta-1 that is encoded in the genome of human.


ADH4_HUMAN All-trans-retinol dehydrogenase [NAD(+)] ADH4 (sprot)

An all-trans-retinol dehydrogenase [NAD(+)] ADH4 that is encoded in the genome of human.


RDH5_HUMAN Retinol dehydrogenase 5 (sprot)

A retinol dehydrogenase 5 that is encoded in the genome of human.


H17B6_HUMAN 17-beta-hydroxysteroid dehydrogenase type 6 (sprot)

A 17-beta-hydroxysteroid dehydrogenase type 6 that is encoded in the genome of human.


RABP1_CHICK Cellular retinoic acid-binding protein 1 (sprot)

A cellular retinoic acid-binding protein 1 that is encoded in the genome of chicken.


Isoxicam

A monocarboxylic acid amide that is piroxicam in which the pyrid-2-yl group is replaced by a 5-methyl-1,2-oxazol-3-yl group. A non-steroidal anti-inflammatory drug, it was withdrawn from the market in the 1980s following its association with cases of Stevens-Johnson syndrome.


CAC1C_MOUSE Voltage-dependent L-type calcium channel subunit alpha-1C (sprot)

A voltage-dependent L-type calcium channel subunit alpha-1C that is encoded in the genome of mouse.


FABH_ECOLI Beta-ketoacyl-[acyl-carrier-protein] synthase III (sprot)

A beta-ketoacyl-[acyl-carrier-protein] synthase III that is encoded in the genome of Escherichia coli K-12.


CXB2_HUMAN Gap junction beta-2 protein (sprot)

A gap junction beta-2 protein that is encoded in the genome of human.


CXA1_HUMAN Gap junction alpha-1 protein (sprot)

A gap junction alpha-1 protein that is encoded in the genome of human.


Bekanamycin

kanendomycin is the sulfate of bekanamycin; RN given refers to parent cpd; structure


C3TDZ2_ECOLX Beta-ketoacyl-[acyl-carrier-protein] synthase III (trembl)


VMAT1_HUMAN Chromaffin granule amine transporter (sprot)

A chromaffin granule amine transporter that is encoded in the genome of human.


5HT1B_MOUSE 5-hydroxytryptamine receptor 1B (sprot)

A 5-hydroxytryptamine receptor 1B that is encoded in the genome of mouse.


VMAT2_MOUSE Synaptic vesicular amine transporter (sprot)

A synaptic vesicular amine transporter that is encoded in the genome of mouse.


SGMR1_MOUSE Sigma non-opioid intracellular receptor 1 (sprot)

A sigma non-opioid intracellular receptor 1 that is encoded in the genome of mouse.


OPRK_MOUSE Kappa-type opioid receptor (sprot)

A kappa-type opioid receptor that is encoded in the genome of mouse.


PAK1_HUMAN Serine/threonine-protein kinase PAK 1 (sprot)

A serine/threonine-protein kinase PAK 1 that is encoded in the genome of human.


GNRHR_RAT Gonadotropin-releasing hormone receptor (sprot)

A gonadotropin-releasing hormone I receptor that is encoded in the genome of rat.


CP24A_HUMAN 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (sprot)

A 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial that is encoded in the genome of human.


CP21A_HUMAN Steroid 21-hydroxylase (sprot)

A steroid 21-hydroxylase that is encoded in the genome of human.


C11B1_BOVIN Cytochrome P450 11B1, mitochondrial (sprot)

A protein that is a translation product of the CYP11B1 gene in cow.


CP11A_RAT Cholesterol side-chain cleavage enzyme, mitochondrial (sprot)

A cytochrome P450 11A1, mitochondrial that is encoded in the genome of rat.


CP24A_RAT 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (sprot)

A 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial that is encoded in the genome of rat.


CP7A1_RAT Cytochrome P450 7A1 (sprot)

A cytochrome P450 7A1 that is encoded in the genome of rat.


CP51A_RAT Lanosterol 14-alpha demethylase (sprot)

A lanosterol 14-alpha demethylase that is encoded in the genome of rat.


CP17A_RAT Steroid 17-alpha-hydroxylase/17,20 lyase (sprot)

A cytochrome P450 17A1 that is encoded in the genome of rat.


CP27B_MOUSE 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (sprot)

A 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial that is encoded in the genome of mouse.


STE24_YEAST CAAX prenyl protease 1 (sprot)

A CAAX prenyl protease 1 that is encoded in the genome of yeast.


LEG8_HUMAN Galectin-8 (sprot)

A galectin-8 that is encoded in the genome of human.


LEG9_HUMAN Galectin-9 (sprot)

A galectin-9 that is encoded in the genome of human.


LEG3_HUMAN Galectin-3 (sprot)

A galectin-3 that is encoded in the genome of human.


SCNAA_RAT Sodium channel protein type 10 subunit alpha (sprot)

A sodium channel protein type 10 subunit alpha that is encoded in the genome of rat.


SSR2_HUMAN Somatostatin receptor type 2 (sprot)

A somatostatin receptor type 2 that is encoded in the genome of human.


SSR3_HUMAN Somatostatin receptor type 3 (sprot)

A somatostatin receptor type 3 that is encoded in the genome of human.


SSR2_MOUSE Somatostatin receptor type 2 (sprot)

A somatostatin receptor type 2 that is encoded in the genome of mouse.


SSR3_MOUSE Somatostatin receptor type 3 (sprot)

A somatostatin receptor type 3 that is encoded in the genome of mouse.


SSR5_RAT Somatostatin receptor type 5 (sprot)

A somatostatin receptor type 5 that is encoded in the genome of rat.


SSR1_HUMAN Somatostatin receptor type 1 (sprot)

A somatostatin receptor type 1 that is encoded in the genome of human.


SSR2_RAT Somatostatin receptor type 2 (sprot)

A somatostatin receptor type 2 that is encoded in the genome of rat.


SSR3_RAT Somatostatin receptor type 3 (sprot)

A somatostatin receptor type 3 that is encoded in the genome of rat.


PHOP1_HUMAN Phosphoethanolamine/phosphocholine phosphatase (sprot)

A phosphoethanolamine/phosphocholine phosphatase that is encoded in the genome of human.


TAU_HUMAN Microtubule-associated protein tau (sprot)

A microtubule-associated protein tau that is encoded in the genome of human.


DDAH1_HUMAN N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (sprot)

An N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 that is encoded in the genome of human.


ENASE_HUMAN Cytosolic endo-beta-N-acetylglucosaminidase (sprot)

A cytosolic endo-beta-N-acetylglucosaminidase that is encoded in the genome of human.


MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 (sprot)

A dual specificity mitogen-activated protein kinase kinase 7 that is encoded in the genome of human.


P3C2B_HUMAN Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (sprot)

A phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta that is encoded in the genome of human.


P3C2G_HUMAN Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (sprot)

A phosphatidylinositol 3-kinase C2 domain-containing subunit gamma that is encoded in the genome of human.


GPC6A_HUMAN G-protein coupled receptor family C group 6 member A (sprot)

A G-protein coupled receptor family C group 6 member A that is encoded in the genome of human.


S2512_HUMAN Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (sprot)

An electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial that is encoded in the genome of human.


AATC_HUMAN Aspartate aminotransferase, cytoplasmic (sprot)

An aspartate aminotransferase, cytoplasmic that is encoded in the genome of human.


ACY2_HUMAN Aspartoacylase (sprot)

An aspartoacylase that is encoded in the genome of human.


ASNS_HUMAN Asparagine synthetase [glutamine-hydrolyzing] (sprot)

An asparagine synthetase [glutamine-hydrolyzing] that is encoded in the genome of human.


ASSY_HUMAN Argininosuccinate synthase (sprot)

An argininosuccinate synthase that is encoded in the genome of human.


ACY1_HUMAN Aminoacylase-1 (sprot)

An aminoacylase-1 that is encoded in the genome of human.


AATM_HUMAN Aspartate aminotransferase, mitochondrial (sprot)

An aspartate aminotransferase, mitochondrial that is encoded in the genome of human.


SYDC_HUMAN Aspartate--tRNA ligase, cytoplasmic (sprot)

An aspartate--tRNA ligase, cytoplasmic that is encoded in the genome of human.


S2513_HUMAN Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (sprot)

An electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial that is encoded in the genome of human.


GLT_PYRHO Glutamate transporter homolog (sprot)


DAPA_ECOLI 4-hydroxy-tetrahydrodipicolinate synthase (sprot)

A 4-hydroxy-tetrahydrodipicolinate synthase that is encoded in the genome of Escherichia coli K-12.


PYRD_MOUSE Dihydroorotate dehydrogenase (quinone), mitochondrial (sprot)

A dihydroorotate dehydrogenase (quinone), mitochondrial that is encoded in the genome of mouse.


Levallorphan

An opioid antagonist with properties similar to those of NALOXONE; in addition it also possesses some agonist properties. It should be used cautiously; levallorphan reverses severe opioid-induced respiratory depression but may exacerbate respiratory depression such as that induced by alcohol or other non-opioid central depressants. (From Martindale, The Extra Pharmacopoeia, 30th ed, p683)


ACH6_CAEEL Acetylcholine receptor subunit alpha-type unc-63 (sprot)

A neuronal acetylcholine receptor subunit alpha-2 that is encoded in the genome of worm.


O96760_ASCSU Nicotinic acetylcholine receptor alpha subunit (Fragment) (trembl)


PPBT_BOVIN Alkaline phosphatase, tissue-nonspecific isozyme (sprot)

An alkaline phosphatase, tissue-nonspecific isozyme that is encoded in the genome of cow.


PPBI_HUMAN Intestinal-type alkaline phosphatase (sprot)

An intestinal alkaline phosphatase that is encoded in the genome of human.


Levamfetamine

A 1-phenylpropan-2-amine that has R configuration.


SV2A_RAT Synaptic vesicle glycoprotein 2A (sprot)

A synaptic vesicle glycoprotein 2A that is encoded in the genome of rat.


SV2A_HUMAN Synaptic vesicle glycoprotein 2A (sprot)

A synaptic vesicle glycoprotein 2A that is encoded in the genome of human.


NTR2_HUMAN Neurotensin receptor type 2 (sprot)

A neurotensin receptor type 2 that is encoded in the genome of human.


NTR2_RAT Neurotensin receptor type 2 (sprot)

A neurotensin receptor type 2 that is encoded in the genome of rat.


NTR2_MOUSE Neurotensin receptor type 2 (sprot)

A neurotensin receptor type 2 that is encoded in the genome of mouse.


KCNJ8_HUMAN ATP-sensitive inward rectifier potassium channel 8 (sprot)

An ATP-sensitive inward rectifier potassium channel 8 that is encoded in the genome of human.


TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (sprot)

A troponin C, slow skeletal and cardiac muscles that is encoded in the genome of human.


Lidoflazine

Coronary vasodilator with some antiarrhythmic action.


GBRB_MUSDO Gamma-aminobutyric acid receptor subunit beta (sprot)


H9U2V9_TETUR GABA-gated chloride channel 1 (trembl)


H9U2W0_TETUR GABA-gated chloride channel 2 (Fragment) (trembl)


H9U2W1_TETUR GABA-gated chloride channel 3 (Fragment) (trembl)


E0V9W2_PEDHC Gaba-gated chloride channel, putative (trembl)


E0VY07_PEDHC Gaba-gated chloride channel, putative (trembl)


E0W492_PEDHC Gaba-gated chloride channel, putative (trembl)


SDHA_HUMAN Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (sprot)

A succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial that is encoded in the genome of human.


PCNA_HUMAN Proliferating cell nuclear antigen (sprot)

A proliferating cell nuclear antigen that is encoded in the genome of human.


Lonazolac

A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by a 3-(4-chlorophenyl)-1-phenylpyrazol-4-yl group.


MEN1_HUMAN Menin (sprot)

A menin that is encoded in the genome of human.


FACE1_MOUSE CAAX prenyl protease 1 homolog (sprot)

A CAAX prenyl protease 1 that is encoded in the genome of mouse.


S6A15_HUMAN Sodium-dependent neutral amino acid transporter B(0)AT2 (sprot)

A sodium-dependent neutral amino acid transporter B(0)AT2 that is encoded in the genome of human.


AGTR2_HUMAN Type-2 angiotensin II receptor (sprot)

An angiotensin II receptor 2 that is encoded in the genome of human.


AGTR1_CAVPO Type-1 angiotensin II receptor (sprot)


HCAR3_HUMAN Hydroxycarboxylic acid receptor 3 (sprot)

A hydroxycarboxylic acid receptor 3 that is encoded in the genome of human.


HMDH_MOUSE 3-hydroxy-3-methylglutaryl-coenzyme A reductase (sprot)

A 3-hydroxy-3-methylglutaryl-coenzyme A reductase that is encoded in the genome of mouse.


ITAL_HUMAN Integrin alpha-L (sprot)

An integrin alpha-L that is encoded in the genome of human.


Q95214_RABIT Acyl-CoA:cholesterol acyltransferase (Fragment) (trembl)


KCNT1_HUMAN Potassium channel subfamily T member 1 (sprot)

A potassium channel subfamily T member 1 that is encoded in the genome of human.


Loxiglumide

cholecystokinin receptor antagonist; RN refers to (+-)-isomer


Lucanthone

One of the SCHISTOSOMICIDES, it has been replaced largely by HYCANTHONE and more recently PRAZIQUANTEL. (From Martindale The Extrapharmacopoeia, 30th ed., p46)

A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.


DHPS_ECOLI Dihydropteroate synthase (sprot)

A dihydropteroate synthase that is encoded in the genome of Escherichia coli K-12.


A2PZ98_9NEOP Carboxylic ester hydrolase (trembl)


Q39829_SOYBN Lipoxygenase (Fragment) (trembl)


CCR5_MOUSE C-C chemokine receptor type 5 (sprot)

A C-C chemokine receptor type 5 that is encoded in the genome of mouse.


CCR5_MACMU C-C chemokine receptor type 5 (sprot)


IGF1R_HUMAN Insulin-like growth factor 1 receptor (sprot)

An insulin-like growth factor 1 receptor that is encoded in the genome of human.


LT4R1_HUMAN Leukotriene B4 receptor 1 (sprot)

A leukotriene B4 receptor 1 that is encoded in the genome of human.


LOX1_SOYBN Seed linoleate 13S-lipoxygenase-1 (sprot)

A protein that is a translation product of the LOX1.1 gene in Glycine max.


LOX5_MOUSE Polyunsaturated fatty acid 5-lipoxygenase (sprot)

A polyunsaturated fatty acid 5-lipoxygenase that is encoded in the genome of mouse.


HPL_SOLLC Fatty acid hydroperoxide lyase, chloroplastic (sprot)


Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 (trembl)


ACHB3_HUMAN Neuronal acetylcholine receptor subunit beta-3 (sprot)

A neuronal acetylcholine receptor subunit beta-3 that is encoded in the genome of human.


AMDINOCILLIN

An amidinopenicillanic acid derivative with broad spectrum antibacterial action.


NR1I3_MOUSE Nuclear receptor subfamily 1 group I member 3 (sprot)

A nuclear receptor subfamily 1 group I member 3 that is encoded in the genome of mouse.


Medazepam

A benzodiazepine derivative used in the treatment of anxiety. It has sedative, muscle relaxant, and anticonvulsant properties. One of its metabolites is DIAZEPAM and one of its excretion products is OXAZEPAM.


P90584_PLAFA MO15-related protein kinase Pfmrk (trembl)


Meglutol

An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.

A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.


RORA_HUMAN Nuclear receptor ROR-alpha (sprot)

A nuclear receptor ROR-alpha that is encoded in the genome of human.


MTR1C_XENLA Melatonin receptor type 1C (sprot)


LAT1_RAT Large neutral amino acids transporter small subunit 1 (sprot)

A large neutral amino acids transporter small subunit 1 that is encoded in the genome of rat.


Menadione

A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia.


MPIP2_HUMAN M-phase inducer phosphatase 2 (sprot)

An M-phase inducer phosphatase 2 that is encoded in the genome of human.


MPIP3_HUMAN M-phase inducer phosphatase 3 (sprot)

An M-phase inducer phosphatase 3 that is encoded in the genome of human.


UCHL3_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L3 (sprot)

A ubiquitin carboxyl-terminal hydrolase isozyme L3 that is encoded in the genome of human.


MPIP1_HUMAN M-phase inducer phosphatase 1 (sprot)

An M-phase inducer phosphatase 1 that is encoded in the genome of human.


DUS6_RAT Dual specificity protein phosphatase 6 (sprot)

A dual specificity protein phosphatase 6 that is encoded in the genome of rat.


DUS1_MOUSE Dual specificity protein phosphatase 1 (sprot)

A dual specificity protein phosphatase 1 that is encoded in the genome of mouse.


Menadione bisulfite

A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

An organosulfonic acid obtained by formal hydrosulfonation across the 2 and 3 positions of menadione.


MALT1_HUMAN Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (sprot)

A mucosa-associated lymphoid tissue lymphoma translocation protein 1 that is encoded in the genome of human.


Meproscillarin

semi-synthetic derivative of proscillaridin of Scilla (Liliaceae); structure in Negwer, 5th ed, #6625; RN given refers to (3beta)-isomer


Q389T8_TRYB2 Trypanothione reductase (trembl)


An amidophosphoribosyltransferase that is encoded in the genome of human.


TNFA_HUMAN Tumor necrosis factor (sprot)

A tumor necrosis factor that is encoded in the genome of human.


HAOX1_MOUSE 2-Hydroxyacid oxidase 1 (sprot)

A 2-hydroxyacid oxidase 1 that is encoded in the genome of mouse.


Metergoline

A dopamine agonist and serotonin antagonist. It has been used similarly to BROMOCRIPTINE as a dopamine agonist and also for MIGRAINE DISORDERS therapy.

An ergoline alkaloid that is the N-benzyloxycarbonyl derivative of lysergamine. A 5-HT2 antagonist. Also 5-HT1 antagonist and 5-HT1D ligand. Has moderate affinity for 5-HT6 and high affinity for 5-HT7.


AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 (sprot)

A 5'-AMP-activated protein kinase subunit beta-1 that is encoded in the genome of human.


NDUA4_HUMAN Cytochrome c oxidase subunit NDUFA4 (sprot)

A cytochrome c oxidase subunit NDUFA4 that is encoded in the genome of human.


ACPM_HUMAN Acyl carrier protein, mitochondrial (sprot)

An acyl carrier protein, mitochondrial that is encoded in the genome of human.


NDUA1_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 that is encoded in the genome of human.


NDUS4_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial that is encoded in the genome of human.


NDUB5_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial that is encoded in the genome of human.


NDUB3_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 that is encoded in the genome of human.


NDUC1_HUMAN NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial that is encoded in the genome of human.


NDUA2_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 that is encoded in the genome of human.


NDUS5_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 (sprot)

An NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 that is encoded in the genome of human.


NDUS6_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial that is encoded in the genome of human.


NDUB1_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 that is encoded in the genome of human.


NDUS3_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial that is encoded in the genome of human.


NDUB6_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 that is encoded in the genome of human.


NDUA3_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 that is encoded in the genome of human.


NDUB4_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 that is encoded in the genome of human.


NDUB8_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial that is encoded in the genome of human.


NDUB2_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial that is encoded in the genome of human.


NDUA7_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 that is encoded in the genome of human.


NDUC2_HUMAN NADH dehydrogenase [ubiquinone] 1 subunit C2 (sprot)

An NADH dehydrogenase [ubiquinone] 1 subunit C2 that is encoded in the genome of human.


NDUBA_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 that is encoded in the genome of human.


NU1M_HUMAN NADH-ubiquinone oxidoreductase chain 1 (sprot)

An NADH-ubiquinone oxidoreductase chain 1 that is encoded in the genome of human.


NU2M_HUMAN NADH-ubiquinone oxidoreductase chain 2 (sprot)

An NADH-ubiquinone oxidoreductase chain 2 that is encoded in the genome of human.


NU3M_HUMAN NADH-ubiquinone oxidoreductase chain 3 (sprot)

An NADH-ubiquinone oxidoreductase chain 3 that is encoded in the genome of human.


NU4LM_HUMAN NADH-ubiquinone oxidoreductase chain 4L (sprot)

An NADH-ubiquinone oxidoreductase chain 4L that is encoded in the genome of human.


NU4M_HUMAN NADH-ubiquinone oxidoreductase chain 4 (sprot)

An NADH-ubiquinone oxidoreductase chain 4 that is encoded in the genome of human.


NU5M_HUMAN NADH-ubiquinone oxidoreductase chain 5 (sprot)

An NADH-ubiquinone oxidoreductase chain 5 that is encoded in the genome of human.


NU6M_HUMAN NADH-ubiquinone oxidoreductase chain 6 (sprot)

An NADH-ubiquinone oxidoreductase chain 6 that is encoded in the genome of human.


NDUB7_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 that is encoded in the genome of human.


NDUA8_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 that is encoded in the genome of human.


NDUV3_HUMAN NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial that is encoded in the genome of human.


NDUA6_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 that is encoded in the genome of human.


NDUA5_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 that is encoded in the genome of human.


NDUAB_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 that is encoded in the genome of human.


NDUF2_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 that is encoded in the genome of human.


NDUF3_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 that is encoded in the genome of human.


NUA4L_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 that is encoded in the genome of human.


NDUBB_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial that is encoded in the genome of human.


NDUF4_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 that is encoded in the genome of human.


NDUAD_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 that is encoded in the genome of human.


NDUAC_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 that is encoded in the genome of human.


CIA30_HUMAN Complex I intermediate-associated protein 30, mitochondrial (sprot)

A complex I intermediate-associated protein 30, mitochondrial that is encoded in the genome of human.


NDUB9_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 that is encoded in the genome of human.


NDUS8_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial that is encoded in the genome of human.


NDUS7_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial that is encoded in the genome of human.


NDUS2_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial that is encoded in the genome of human.


NDUAA_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial that is encoded in the genome of human.


NDUV2_HUMAN NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial that is encoded in the genome of human.


NDUS1_HUMAN NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (sprot)

An NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial that is encoded in the genome of human.


NDUV1_HUMAN NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial that is encoded in the genome of human.


NDUA9_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial that is encoded in the genome of human.


RAD52_HUMAN DNA repair protein RAD52 homolog (sprot)

A DNA repair protein RAD52 homolog that is encoded in the genome of human.


ACH10_HUMAN Neuronal acetylcholine receptor subunit alpha-10 (sprot)

A neuronal acetylcholine receptor subunit alpha-10 that is encoded in the genome of human.


VMAT2_RAT Synaptic vesicular amine transporter (sprot)

A synaptic vesicular amine transporter that is encoded in the genome of rat.


Methaqualone

A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)

A member of the class of quinazolines that is quinazolin-4-one substituted at positions 2 and 3 by methyl and  o-tolyl groups respectively. A depressant that increases the activity of the GABA receptors in the brain and nervous system, it is used as a sedative and hypnotic medication. It became popular as a recreational drug and club drug in the late 1960s and 1970s.


PBP_STAAU Beta-lactam-inducible penicillin-binding protein (sprot)


NADE_ECOLI NH(3)-dependent NAD(+) synthetase (sprot)

An NH(3)-dependent NAD(+) synthetase that is encoded in the genome of Escherichia coli K-12.


DOPO_BOVIN Dopamine beta-hydroxylase (sprot)

A dopamine beta-hydroxylase that is encoded in the genome of cow.


FOLR2_HUMAN Folate receptor beta (sprot)

A folate receptor beta that is encoded in the genome of human.


PCFT_HUMAN Proton-coupled folate transporter (sprot)

A proton-coupled folate transporter that is encoded in the genome of human.


DRTS_LEIMA Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)

A protein that is a translation product of the LmjF06.0860 gene in Leishmania major.


C3SWJ7_ECOLX Thymidylate synthase (trembl)


PTR1_LEIMA Pteridine reductase 1 (sprot)

A protein that is a translation product of the PTR1 gene in Leishmania major.


DYR_STAAU Dihydrofolate reductase (sprot)

A protein that is a translation product of the folA gene in Staphylococcus aureus.


Q81R22_BACAN Dihydrofolate reductase (trembl)


DYR_ENTFC Dihydrofolate reductase (sprot)


S19A1_HUMAN Reduced folate transporter (sprot)

A reduced folate transporter that is encoded in the genome of human.


FOLR1_HUMAN Folate receptor alpha (sprot)

A folate receptor alpha that is encoded in the genome of human.


PUR9_HUMAN Bifunctional purine biosynthesis protein ATIC (sprot)

A bifunctional purine biosynthesis protein ATIC that is encoded in the genome of human.


Methoxyflurane

An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with NITROUS OXIDE to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)

An ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl.


GSHR_PLAF7 Glutathione reductase (sprot)


Methylparaben

used as a preservative in cosmetics but potentiates UV-induced damage of skin; RN given refers to parent cpd

A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.


Methysergide

An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.


Metiazinic acid

phenothiazine which acts as an anti-inflammatory agent; minor descriptor (75-86); on line & INDEX MEDICUS search PHENOTHIAZINES (75-86)

Phenothiazine substituted at nitrogen by a methyl group and at C-2 by a carboxymethyl group.


5HT3B_MOUSE 5-hydroxytryptamine receptor 3B (sprot)

A 5-hydroxytryptamine receptor 3B that is encoded in the genome of mouse.


C4LW95_ENTH1 Thioredoxin reductase (trembl)


C11B1_RAT Cytochrome P450 11B1, mitochondrial (sprot)

A protein that is a translation product of the Cyp11b1 gene in rat.


TY3H_HUMAN Tyrosine 3-monooxygenase (sprot)

A tyrosine 3-monooxygenase that is encoded in the genome of human.


SCN9A_MOUSE Sodium channel protein type 9 subunit alpha (sprot)

A sodium channel protein type 9 subunit alpha that is encoded in the genome of mouse.


SCN1A_MOUSE Sodium channel protein type 1 subunit alpha (sprot)

A sodium channel protein type 1 subunit alpha that is encoded in the genome of mouse.


CNR2_HUMAN Cannabinoid receptor 2 (sprot)

A cannabinoid receptor 2 that is encoded in the genome of human.


ALBU_HUMAN Albumin (sprot)

An albumin that is encoded in the genome of human.


IL1R1_HUMAN Interleukin-1 receptor type 1 (sprot)

An interleukin-1 receptor type 1 that is encoded in the genome of human.


PTGDS_HUMAN Prostaglandin-H2 D-isomerase (sprot)

A prostaglandin-H2 D-isomerase that is encoded in the genome of human.


CAC1E_RAT Voltage-dependent R-type calcium channel subunit alpha-1E (sprot)

A voltage-dependent R-type calcium channel subunit alpha-1E that is encoded in the genome of rat.


CAC1A_RAT Voltage-dependent P/Q-type calcium channel subunit alpha-1A (sprot)

A voltage-dependent P/Q-type calcium channel subunit alpha-1A that is encoded in the genome of rat.


SCN4A_RAT Sodium channel protein type 4 subunit alpha (sprot)

A sodium channel protein type 4 subunit alpha that is encoded in the genome of rat.


O13428_CANAX 1,3-beta-glucan synthase (trembl)


CP2A6_HUMAN Cytochrome P450 2A6 (sprot)

A cytochrome P450 2A that is a translation product of the CYP2A6 gene in human.


GDE_RABIT Glycogen debranching enzyme (sprot)

A glycogen debranching enzyme that is encoded in the genome of rabbit.


LPH_HUMAN Lactase/phlorizin hydrolase (sprot)

A lactase/phlorizin hydrolase that is encoded in the genome of human.


BGAL_BOVIN Beta-galactosidase (sprot)

A eukaryotic-type beta-galactosidase that is encoded in the genome of cow.


GBA2_MOUSE Non-lysosomal glucosylceramidase (sprot)

A non-lysosomal glucosylceramidase that is encoded in the genome of mouse.


GBA2_HUMAN Non-lysosomal glucosylceramidase (sprot)

A non-lysosomal glucosylceramidase that is encoded in the genome of human.


GDE_HUMAN Glycogen debranching enzyme (sprot)

A glycogen debranching enzyme that is encoded in the genome of human.


LYAG_MOUSE Lysosomal alpha-glucosidase (sprot)

A lysosomal alpha-glucosidase that is encoded in the genome of mouse.


O70282_RAT Trehalase (Fragment) (trembl)


CEGT_MOUSE Ceramide glucosyltransferase (sprot)

A ceramide glucosyltransferase that is encoded in the genome of mouse.


PDE5A_BOVIN cGMP-specific 3',5'-cyclic phosphodiesterase (sprot)

A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of cow.


PDE4A_CAVPO cAMP-specific 3',5'-cyclic phosphodiesterase 4A (Fragment) (sprot)


AKT1_HUMAN RAC-alpha serine/threonine-protein kinase (sprot)

A RAC-alpha serine/threonine-protein kinase that is encoded in the genome of human.


L-mimosine

3-Hydroxy-4-oxo-1(4H)-pyridinealanine. An antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca.

An L-alpha-amino acid that is propionic acid substituted by an amino group at position 2 and a 3-hydroxy-4-oxopyridin-1(4H)-yl group at position 3 (the 2S-stereoisomer). It a non-protein plant amino acid isolated from Mimosa pudica.


GLYC_HUMAN Serine hydroxymethyltransferase, cytosolic (sprot)

A serine hydroxymethyltransferase, cytosolic that is encoded in the genome of human.


RIR1_HHV11 Ribonucleoside-diphosphate reductase large subunit (sprot)


Minaprine

Agr 1240 refers to di-HCl; short-acting type A MAO inhibitor (MAOI) of mild potency; structure


RS4_CHLPN Small ribosomal subunit protein uS4 (sprot)


RS9_CHLPN Small ribosomal subunit protein uS9 (sprot)


KCNJ1_HUMAN ATP-sensitive inward rectifier potassium channel 1 (sprot)

An ATP-sensitive inward rectifier potassium channel 1 that is encoded in the genome of human.


ADX_HUMAN Adrenodoxin, mitochondrial (sprot)

An adrenodoxin, mitochondrial that is encoded in the genome of human.


ROS1_HUMAN Proto-oncogene tyrosine-protein kinase ROS (sprot)

A proto-oncogene tyrosine-protein kinase ROS that is encoded in the genome of human.


DYR1A_RAT Dual specificity tyrosine-phosphorylation-regulated kinase 1A (sprot)

A dual specificity tyrosine-phosphorylation-regulated kinase 1A that is encoded in the genome of rat.


TADBP_HUMAN TAR DNA-binding protein 43 (sprot)

A TAR DNA-binding protein 43 that is encoded in the genome of human.


AOFA_BOVIN Amine oxidase [flavin-containing] A (sprot)

An amine oxidase [flavin-containing] A that is encoded in the genome of cow.


Mofezolac

Cyclooxygenase 1 inhibitor; ; RN from Toxlit


Monobenzone

The monobenzyl ether of hydroquinone.  It is used as a topical drug for medical depigmentation.


CLTR2_HUMAN Cysteinyl leukotriene receptor 2 (sprot)

A cysteinyl leukotriene receptor 2 that is encoded in the genome of human.


GPR17_MOUSE Uracil nucleotide/cysteinyl leukotriene receptor (sprot)

A uracil nucleotide/cysteinyl leukotriene receptor that is encoded in the genome of mouse.


OPRM_BOVIN Mu-type opioid receptor (sprot)

A mu-type opioid receptor that is encoded in the genome of cow.


OPRX_CAVPO Nociceptin receptor (sprot)

A nociceptin receptor that is encoded in the genome of guinea pig.


B3DH72_DANRE Opioid receptor, delta 1b (trembl)


Latamoxef

Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.

A broad-spectrum oxacephem antibiotic in which the oxazine ring is substituted with a tetrazolylthiomethyl group and the azetidinone ring carries methoxy and 2-carboxy-2-(4-hydroxyphenyl)acetamido substituents.


SYI_ECOLI Isoleucine--tRNA ligase (sprot)

An isoleucine--tRNA ligase that is encoded in the genome of Escherichia coli K-12.


SYIC_HUMAN Isoleucine--tRNA ligase, cytoplasmic (sprot)

An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of human.


SYI1_STAAU Isoleucine--tRNA ligase (sprot)


SYI_STRP1 Isoleucine--tRNA ligase (sprot)

An isoleucine--tRNA ligase that is encoded in the genome of Streptococcus pyogenes serotype M1.


SYI_THET8 Isoleucine--tRNA ligase (sprot)


Q8I5G6_PLAF7 Isoleucine--tRNA ligase, putative (trembl)


IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenase 1 (sprot)

An inosine-5'-monophosphate dehydrogenase 1 that is encoded in the genome of human.


IMDH2_HUMAN Inosine-5'-monophosphate dehydrogenase 2 (sprot)

An inosine-5'-monophosphate dehydrogenase 2 that is encoded in the genome of human.


IMDH_CRYNJ Inosine-5'-monophosphate dehydrogenase (sprot)


CNR1_RAT Cannabinoid receptor 1 (sprot)

A cannabinoid receptor 1 that is encoded in the genome of rat.


CNR2_MOUSE Cannabinoid receptor 2 (sprot)

A cannabinoid receptor 2 that is encoded in the genome of mouse.


ST14_HUMAN Suppressor of tumorigenicity 14 protein (sprot)

A suppressor of tumorigenicity 14 protein that is encoded in the genome of human.


C1R_HUMAN Complement C1r subcomponent (sprot)

A complement C1r subcomponent that is encoded in the genome of human.


C1S_HUMAN Complement C1s subcomponent (sprot)

A complement C1s subcomponent that is encoded in the genome of human.


TRYB1_HUMAN Tryptase alpha/beta-1 (sprot)

A tryptase alpha/beta-1 that is encoded in the genome of human.


FA12_HUMAN Coagulation factor XII (sprot)

A coagulation factor XII that is encoded in the genome of human.


CRTN_STAAE 4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (sprot)


Nalorphine

A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.


Nemonapride

an atypical antipsychotic approved in Japan for the treatment of schizophrenia

A racemate composed of (2S,3S)- and (2R,3R)-enantiomers of nemonapride. Highly potent dopamine D2-like receptor antagonist; selective over D1-like receptors (Ki values are 0.1 and 740 nM for D2-like and D1-like receptors respectively). Also potent 5-HT1A receptor agonist (IC50 = 34 nM) and has affinity for sigma receptors.


RS12_ECOLI Small ribosomal subunit protein uS12 (sprot)

A 30S ribosomal protein S12 that is encoded in the genome of Escherichia coli K-12.


SYFA_ECOLI Phenylalanine--tRNA ligase alpha subunit (sprot)

A prokaryotic-type phenylalanine--tRNA ligase alpha subunit that is encoded in the genome of Escherichia coli K-12.


SYFB_ECOLI Phenylalanine--tRNA ligase beta subunit (sprot)

A prokaryotic-type phenylalanine--tRNA ligase beta subunit that is encoded in the genome of Escherichia coli K-12.


LRAT_HUMAN Lecithin retinol acyltransferase (sprot)

A lecithin retinol acyltransferase that is encoded in the genome of human.


CASR_RAT Extracellular calcium-sensing receptor (sprot)

An extracellular calcium-sensing receptor that is encoded in the genome of rat.


NNMT_HUMAN Nicotinamide N-methyltransferase (sprot)

A nicotinamide N-methyltransferase that is encoded in the genome of human.


NADC_HUMAN Nicotinate-nucleotide pyrophosphorylase [carboxylating] (sprot)

A nicotinate-nucleotide pyrophosphorylase [carboxylating] that is encoded in the genome of human.


SIR1_HUMAN NAD-dependent protein deacetylase sirtuin-1 (sprot)

An NAD-dependent protein deacetylase sirtuin-1 that is encoded in the genome of human.


SIR2_HUMAN NAD-dependent protein deacetylase sirtuin-2 (sprot)

An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of human.


HST2_YEAST NAD-dependent protein deacetylase HST2 (sprot)

An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of yeast.


SIR3_HUMAN NAD-dependent protein deacetylase sirtuin-3, mitochondrial (sprot)

An NAD-dependent protein deacetylase sirtuin-3, mitochondrial that is encoded in the genome of human.


SARM1_HUMAN NAD(+) hydrolase SARM1 (sprot)

An NAD(+) hydrolase SARM1 that is encoded in the genome of human.


S29A1_RAT Equilibrative nucleoside transporter 1 (sprot)

An equilibrative nucleoside transporter 1 that is encoded in the genome of rat.


KCNA4_RAT Potassium voltage-gated channel subfamily A member 4 (sprot)

A voltage-gated potassium channel alpha subunit KCNA4 that is encoded in the genome of rat.


Niclosamide

An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48). Although suggested as a potential treatment for COVID-19 based on its broad antiviral activity, including in vitro activity against coronaviruses, there are no data to support the use of niclosamide in the treatment of COVID-19.

A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.


ACHA7_MOUSE Neuronal acetylcholine receptor subunit alpha-7 (sprot)

A neuronal acetylcholine receptor subunit alpha-7 that is encoded in the genome of mouse.


ACHA9_RAT Neuronal acetylcholine receptor subunit alpha-9 (sprot)

A neuronal acetylcholine receptor subunit alpha-9 that is encoded in the genome of rat.


CRTY_PANAN Lycopene beta-cyclase (sprot)


ACH4_DROME Acetylcholine receptor subunit beta-like 2 (sprot)

A protein that is a translation product of the nAChRbeta2 gene in fruit fly.


ACHA4_CHICK Neuronal acetylcholine receptor subunit alpha-4 (sprot)

A neuronal acetylcholine receptor subunit alpha-4 that is encoded in the genome of chicken.


ACHA4_MOUSE Neuronal acetylcholine receptor subunit alpha-4 (sprot)

A neuronal acetylcholine receptor subunit alpha-4 that is encoded in the genome of mouse.


ACHB3_RAT Neuronal acetylcholine receptor subunit beta-3 (sprot)

A neuronal acetylcholine receptor subunit beta-3 that is encoded in the genome of rat.


ACHA5_RAT Neuronal acetylcholine receptor subunit alpha-5 (sprot)

A protein that is a translation product of the Chrna5 gene in rat.


ACHA_RAT Acetylcholine receptor subunit alpha (sprot)

An acetylcholine receptor subunit alpha that is encoded in the genome of rat.


ACHB_RAT Acetylcholine receptor subunit beta (sprot)

An acetylcholine receptor subunit beta that is encoded in the genome of rat.


ACHA6_RAT Neuronal acetylcholine receptor subunit alpha-6 (sprot)

A neuronal acetylcholine receptor subunit alpha-6 that is encoded in the genome of rat.


ACH10_RAT Neuronal acetylcholine receptor subunit alpha-10 (sprot)

A neuronal acetylcholine receptor subunit alpha-10 that is encoded in the genome of rat.


KCND3_RAT Potassium voltage-gated channel subfamily D member 3 (sprot)

A voltage-gated potassium channel KCND3 that is encoded in the genome of rat.


GLRA3_HUMAN Glycine receptor subunit alpha-3 (sprot)

A glycine receptor subunit alpha-3 that is encoded in the genome of human.


CAC1C_CAVPO Voltage-dependent L-type calcium channel subunit alpha-1C (sprot)


KCNA1_MOUSE Potassium voltage-gated channel subfamily A member 1 (sprot)

A voltage-gated potassium channel subunit KCNA1 that is encoded in the genome of mouse.