PCP_HUMAN Lysosomal Pro-X carboxypeptidase (sprot)

A lysosomal Pro-X carboxypeptidase that is encoded in the genome of human.


V1AR_HUMAN Vasopressin V1a receptor (sprot)

A vasopressin V1a receptor that is encoded in the genome of human.


OXYR_MOUSE Oxytocin receptor (sprot)

An oxytocin receptor that is encoded in the genome of mouse.


V2R_HUMAN Vasopressin V2 receptor (sprot)

A vasopressin V2 receptor that is encoded in the genome of human.


OXYR_HUMAN Oxytocin receptor (sprot)

An oxytocin receptor that is encoded in the genome of human.


Q9K2N0_PSEAI Beta-lactamase VIM-2 (trembl)


KDM4E_HUMAN Lysine-specific demethylase 4E (sprot)

A lysine-specific demethylase 4E that is encoded in the genome of human.


PERL_HUMAN Lactoperoxidase (sprot)

A lactoperoxidase that is encoded in the genome of human.


PERT_HUMAN Thyroid peroxidase (sprot)

A thyroid peroxidase that is encoded in the genome of human.


Carubicin

A very toxic anthracycline-type antineoplastic related to DAUNORUBICIN, obtained from Actinomadura carminata.

A toxic anthracycline antibiotic that is produced by Actinomadura carminata and also has potent antineoplastic activity.


MK03_HUMAN Mitogen-activated protein kinase 3 (sprot)

A mitogen-activated protein kinase 3 that is encoded in the genome of human.


FAAH1_RAT Fatty-acid amide hydrolase 1 (sprot)

A fatty-acid amide hydrolase 1 that is encoded in the genome of rat.


ASAH1_RAT Acid ceramidase (sprot)

An acid ceramidase that is encoded in the genome of rat.


ASAH1_HUMAN Acid ceramidase (sprot)

An acid ceramidase that is encoded in the genome of human.


SQOR_HUMAN Sulfide:quinone oxidoreductase, mitochondrial (sprot)

A sulfide:quinone oxidoreductase, mitochondrial that is encoded in the genome of human.


GSHR_HUMAN Glutathione reductase, mitochondrial (sprot)

A glutathione reductase, mitochondrial that is encoded in the genome of human.


CPT1A_HUMAN Carnitine O-palmitoyltransferase 1, liver isoform (sprot)

A carnitine O-palmitoyltransferase 1, liver isoform that is encoded in the genome of human.


CPT1B_RAT Carnitine O-palmitoyltransferase 1, muscle isoform (sprot)

A carnitine O-palmitoyltransferase 1, muscle isoform that is encoded in the genome of rat.


CPT2_RAT Carnitine O-palmitoyltransferase 2, mitochondrial (sprot)

A carnitine O-palmitoyltransferase 2, mitochondrial that is encoded in the genome of rat.


ANPRA_HUMAN Atrial natriuretic peptide receptor 1 (sprot)

An atrial natriuretic peptide receptor 1 that is encoded in the genome of human.


ANPRA_RAT Atrial natriuretic peptide receptor 1 (sprot)

An atrial natriuretic peptide receptor 1 that is encoded in the genome of rat.


Carprofen

anti-inflammatory drug (NSAID) of the propionic acid class with selective inhibition of COX-2 versus COX-1

Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.


CO5_HUMAN Complement C5 (sprot)

A complement C5 that is encoded in the genome of human.


Carumonam

An N-sulfonated monobactam antibiotic.


RYR2_HUMAN Ryanodine receptor 2 (sprot)

A ryanodine receptor 2 that is encoded in the genome of human.


5HT4R_CAVPO 5-hydroxytryptamine receptor 4 (sprot)


PERM_HUMAN Myeloperoxidase (sprot)

A myeloperoxidase that is encoded in the genome of human.


PK3CD_HUMAN Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (sprot)

A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform that is encoded in the genome of human.


PYGM_RABIT Glycogen phosphorylase, muscle form (sprot)

A glycogen phosphorylase, muscle form that is encoded in the genome of rabbit.


AA1R_BOVIN Adenosine receptor A1 (sprot)

An adenosine receptor A1 that is encoded in the genome of cow.


AA1R_CAVPO Adenosine receptor A1 (sprot)

An adenosine receptor A1 that is encoded in the genome of guinea pig.


GUAD_HUMAN Guanine deaminase (sprot)

A guanine deaminase that is encoded in the genome of human.


AA2AR_CAVPO Adenosine receptor A2a (sprot)

An adenosine receptor A2a that is encoded in the genome of guinea pig.


AA2BR_MOUSE Adenosine receptor A2b (sprot)

An adenosine receptor A2b that is encoded in the genome of mouse.


VDR_MOUSE Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of mouse.


CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (sprot)

A 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial that is encoded in the genome of human.


CP2R1_HUMAN Vitamin D 25-hydroxylase (sprot)

A vitamin D 25-hydroxylase that is encoded in the genome of human.


VTDB_HUMAN Vitamin D-binding protein (sprot)

A vitamin D-binding protein that is encoded in the genome of human.


VDR_RAT Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of rat.


VDR_CHICK Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of chicken.


VDR_BOVIN Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of cow.


VDR_PIG Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of pig.


VDRA_DANRE Vitamin D3 receptor A (sprot)

A vitamin D3 receptor that is encoded in the genome of zebrafish.


TRPA1_MOUSE Transient receptor potential cation channel subfamily A member 1 (sprot)

A transient receptor potential cation channel TRPA1 that is encoded in the genome of mouse.


TRY1_HUMAN Serine protease 1 (sprot)

A serine protease 1 that is encoded in the genome of human.


KLK1_HUMAN Kallikrein-1 (sprot)

A kallikrein-1 that is encoded in the genome of human.


PLMN_RAT Plasminogen (sprot)

A plasminogen that is encoded in the genome of rat.


HGFA_HUMAN Hepatocyte growth factor activator (sprot)

A hepatocyte growth factor activator that is encoded in the genome of human.


TMPS2_HUMAN Transmembrane protease serine 2 (sprot)

A transmembrane protease serine 2 that is encoded in the genome of human.


AGTR1_HUMAN Type-1 angiotensin II receptor (sprot)

An angiotensin II receptor 1 that is encoded in the genome of human.


AGTR1_BOVIN Type-1 angiotensin II receptor (sprot)

An angiotensin II receptor 1 that is encoded in the genome of cow.


AGTR1_RABIT Type-1 angiotensin II receptor (sprot)

An angiotensin II receptor 1 that is encoded in the genome of rabbit.


POLK_HUMAN DNA polymerase kappa (sprot)

A DNA polymerase kappa that is encoded in the genome of human.


POLI_HUMAN DNA polymerase iota (sprot)

A DNA polymerase iota that is encoded in the genome of human.


POLH_HUMAN DNA polymerase eta (sprot)

A DNA polymerase eta that is encoded in the genome of human.


ULA1_HUMAN NEDD8-activating enzyme E1 regulatory subunit (sprot)

A NEDD8-activating enzyme E1 regulatory subunit that is encoded in the genome of human.


LKHA4_HUMAN Leukotriene A-4 hydrolase (sprot)

A leukotriene A-4 hydrolase that is encoded in the genome of human.


DAPE_HAEIN Succinyl-diaminopimelate desuccinylase (sprot)


BLAN1_KLEPN Metallo-beta-lactamase type 2 (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the blaNDM-1 gene in Klebsiella pneumoniae.


KCNKA_HUMAN Potassium channel subfamily K member 10 (sprot)

A potassium channel subfamily K member 10 that is encoded in the genome of human.


TLR4_HUMAN Toll-like receptor 4 (sprot)

A Toll-like receptor 4 that is encoded in the genome of human.


Cefacetrile

A derivative of 7-aminocephalosporanic acid.


STRP_STRP1 Streptokinase A (sprot)

A protein that is a translation product of the ska gene in Streptococcus pyogenes serotype M1.


S15A1_HUMAN Solute carrier family 15 member 1 (sprot)

A solute carrier family 15 member 1 that is encoded in the genome of human.


O-Formylcefamandole

A cephalosporin compound having (R)-O-formylmandelamido and N-methylthiotetrazole side groups. It is used (as the sodium salt) as a progrug for cefamandole.


O54286_STAAU Beta-lactam-inducible penicillin-binding protein (trembl)


Q14TG6_HAEIF Peptidoglycan D,D-transpeptidase FtsI (trembl)


Q54906_STRPY Penicillin-binding protein (trembl)


PBPC_BACSU Penicillin-binding protein 3 (sprot)

A protein that is a translation product of the pbpC gene in Bacillus subtilis subsp. subtilis str. 168.


PLCG1_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (sprot)

A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 that is encoded in the genome of human.


Cefmenoxime

A cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The drug has a high rate of efficacy in many types of infection and to date no severe side effects have been noted.

A third-generation cephalosporin antibiotic, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position and a [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl group at the 3-position.


SSR4_HUMAN Somatostatin receptor type 4 (sprot)

A somatostatin receptor type 4 that is encoded in the genome of human.


Ceforanide

A second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many coliforms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species.


COMT_HUMAN Catechol O-methyltransferase (sprot)

A catechol O-methyltransferase that is encoded in the genome of human.


Cefotiam

One of the CEPHALOSPORINS that has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

A cephalosporin with ({1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl}sulfanyl)methyl and (2-amino-1,3-thiazol-4-yl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. A third generation beta-lactam cephalosporin antibiotic, it is active against a broad spectrum of both Gram positive and Gram negative bacteria.


VIPR1_HUMAN Vasoactive intestinal polypeptide receptor 1 (sprot)

A vasoactive intestinal polypeptide receptor 1 that is encoded in the genome of human.


SC6A3_MOUSE Sodium-dependent dopamine transporter (sprot)

A sodium-dependent dopamine transporter that is encoded in the genome of mouse.


Cefpiramide

A third-generation cephalosporin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl and (R)-2-{[(4-hydroxy-6-methylpyridin-3-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It has a broad spectrum of antibacterial activity.


Cefsulodin

A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for Pseudomonas infections in debilitated patients.

A pyridinium-substituted semi-synthetic, broad-spectrum, cephalosporin antibiotic.


ARBK1_HUMAN Beta-adrenergic receptor kinase 1 (sprot)

A beta-adrenergic receptor kinase 1 that is encoded in the genome of human.


PTN11_HUMAN Tyrosine-protein phosphatase non-receptor type 11 (sprot)

A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of human.


PTN6_HUMAN Tyrosine-protein phosphatase non-receptor type 6 (sprot)

A tyrosine-protein phosphatase non-receptor type 6 that is encoded in the genome of human.


5HT4R_MOUSE 5-hydroxytryptamine receptor 4 (sprot)

A 5-hydroxytryptamine receptor 4 that is encoded in the genome of mouse.


SGMR2_RAT Sigma intracellular receptor 2 (sprot)

A sigma intracellular receptor 2 that is encoded in the genome of rat.


AROQ_HELPY 3-dehydroquinate dehydratase (sprot)

A protein that is a translation product of the aroQ gene in Helicobacter pylori 26695.


AROQ_STRCO 3-dehydroquinate dehydratase (sprot)

A protein that is a translation product of the aroQ gene in Streptomyces coelicolor A3(2).


TRPV4_MOUSE Transient receptor potential cation channel subfamily V member 4 (sprot)

A transient receptor potential cation channel TRPV4 that is encoded in the genome of mouse.


DCK_HUMAN Deoxycytidine kinase (sprot)

A deoxycytidine kinase that is encoded in the genome of human.


BLAC_STAAU Beta-lactamase (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the blaZ gene in Staphylococcus aureus.


BLAT_ECOLX Beta-lactamase TEM (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the blaTEM gene in Escherichia coli.


BLO1_ECOLX Beta-lactamase OXA-1 (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the bla gene in Escherichia coli.


BLKPC_KLEPN Carbapenem-hydrolyzing beta-lactamase KPC (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the blaKPC-2 gene in Klebsiella pneumoniae.


Q50H31_BRAPL Class D beta-lactamase (trembl)


Clebopride

antidopaminergic; RN given refers to parent cpd; structure


Clemizole

A member of the class of  benzimidazoles that is 1H-benzimidazole substituted by a pyrrolidin-1-ylmethyl and a 4-chlorobenzyl groups at positions 2 and 1 respectively.


HMOX2_RAT Heme oxygenase 2 (sprot)

A heme oxygenase 2 that is encoded in the genome of rat.


TRPC4_HUMAN Short transient receptor potential channel 4 (sprot)

A short transient receptor potential cation channel TRPC4 that is encoded in the genome of human.


TRPC5_HUMAN Short transient receptor potential channel 5 (sprot)

A short transient receptor potential channel 5 that is encoded in the genome of human.


Q1J5W5_STRPF Penicillin-binding protein (trembl)


Q60FU1_HAEIF Peptidoglycan D,D-transpeptidase FtsI (trembl)


OXDA_HUMAN D-amino-acid oxidase (sprot)

A D-amino-acid oxidase that is encoded in the genome of human.


Cerulenin

An epoxydodecadienamide isolated from several species, including ACREMONIUM, Acrocylindrum, and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.

An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function.


F13A_HUMAN Coagulation factor XIII A chain (sprot)

A coagulation factor XIII A chain that is encoded in the genome of human.


PDE5A_HUMAN cGMP-specific 3',5'-cyclic phosphodiesterase (sprot)

A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of human.


COX2_HUMAN Cytochrome c oxidase subunit 2 (sprot)

A cytochrome c oxidase subunit 2 that is encoded in the genome of human.


PDPK1_HUMAN 3-phosphoinositide-dependent protein kinase 1 (sprot)

A 3-phosphoinositide-dependent protein kinase 1 that is encoded in the genome of human.


PGH2_MOUSE Prostaglandin G/H synthase 2 (sprot)

A prostaglandin G/H synthase 2 that is encoded in the genome of mouse.


PGH1_MOUSE Prostaglandin G/H synthase 1 (sprot)

A prostaglandin G/H synthase 1 that is encoded in the genome of mouse.


PGH2_RAT Prostaglandin G/H synthase 2 (sprot)

A prostaglandin G/H synthase 2 that is encoded in the genome of rat.


PGH1_RAT Prostaglandin G/H synthase 1 (sprot)

A prostaglandin G/H synthase 1 that is encoded in the genome of rat.


PGH1_CANLF Prostaglandin G/H synthase 1 (sprot)


COX2_SHEEP Cytochrome c oxidase subunit 2 (sprot)


PTGES_HUMAN Prostaglandin E synthase (sprot)

A prostaglandin E synthase that is encoded in the genome of human.


COX1_SHEEP Cytochrome c oxidase subunit 1 (sprot)

A cytochrome c oxidase subunit 1 that is encoded in the genome of sheep.


S15A2_HUMAN Solute carrier family 15 member 2 (sprot)

A solute carrier family 15 member 2 that is encoded in the genome of human.


Cephaloglycin

A cephalosporin antibiotic containing at the 7beta-position of the cephem skeleton an (R)-amino(phenyl)acetamido group.


S22AB_HUMAN Solute carrier family 22 member 11 (sprot)

A solute carrier family 22 member 11 that is encoded in the genome of human.


PTN7_HUMAN Tyrosine-protein phosphatase non-receptor type 7 (sprot)

A tyrosine-protein phosphatase non-receptor type 7 that is encoded in the genome of human.


NISCH_HUMAN Nischarin (sprot)

A nischarin that is encoded in the genome of human.


CP3A5_HUMAN Cytochrome P450 3A5 (sprot)

A cytochrome P450 3A5 that is encoded in the genome of human.


FAS_HUMAN Fatty acid synthase (sprot)

A fatty acid synthase that is encoded in the genome of human.


CCKAR_HUMAN Cholecystokinin receptor type A (sprot)

A cholecystokinin receptor 1 that is encoded in the genome of human.


CATE_HUMAN Cathepsin E (sprot)

A cathepsin E that is encoded in the genome of human.


ADAM9_HUMAN Disintegrin and metalloproteinase domain-containing protein 9 (sprot)

A disintegrin and metalloproteinase domain-containing protein 9 that is encoded in the genome of human.


CAT_SALTI Chloramphenicol acetyltransferase (sprot)


TTGR_PSEPK Probable HTH-type transcriptional regulator TtgR (sprot)


BCL2_HUMAN Apoptosis regulator Bcl-2 (sprot)

An apoptosis regulator Bcl-2 that is encoded in the genome of human.


TRFR_HUMAN Thyrotropin-releasing hormone receptor (sprot)

A thyrotropin-releasing hormone receptor type 1 that is encoded in the genome of human.


TRHR_RAT Thyrotropin-releasing hormone receptor (sprot)

A thyrotropin-releasing hormone receptor type 1 that is encoded in the genome of rat.


TRHR_MOUSE Thyrotropin-releasing hormone receptor (sprot)

A thyrotropin-releasing hormone receptor type 1 that is encoded in the genome of mouse.


GBRA1_BOVIN Gamma-aminobutyric acid receptor subunit alpha-1 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-1 that is encoded in the genome of cow.


GBRB1_BOVIN Gamma-aminobutyric acid receptor subunit beta-1 (sprot)

A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of cow.


GBRA2_BOVIN Gamma-aminobutyric acid receptor subunit alpha-2 (sprot)

A protein that is a translation product of any of the 2 copies of the GABRA2 gene in cow.


GBRA3_BOVIN Gamma-aminobutyric acid receptor subunit alpha-3 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-3 that is encoded in the genome of cow.


GBRA4_BOVIN Gamma-aminobutyric acid receptor subunit alpha-4 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-4 that is encoded in the genome of cow.


GBRG2_BOVIN Gamma-aminobutyric acid receptor subunit gamma-2 (sprot)


GASR_HUMAN Gastrin/cholecystokinin type B receptor (sprot)

A cholecystokinin receptor 2 that is encoded in the genome of human.


GASR_RAT Gastrin/cholecystokinin type B receptor (sprot)

A cholecystokinin receptor 2 that is encoded in the genome of rat.


S22A3_HUMAN Solute carrier family 22 member 3 (sprot)

A solute carrier family 22 member 3 that is encoded in the genome of human.


RCE1_YEAST CAAX prenyl protease 2 (sprot)

A protein that is a translation product of the RCE1 gene in yeast.


SYNJ2_HUMAN Synaptojanin-2 (sprot)

A synaptojanin-2 that is encoded in the genome of human.


AT1A2_PIG Sodium/potassium-transporting ATPase subunit alpha-2 (sprot)


FAK1_HUMAN Focal adhesion kinase 1 (sprot)

A focal adhesion kinase 1 that is encoded in the genome of human.


BACE1_HUMAN Beta-secretase 1 (sprot)

A beta-secretase 1 that is encoded in the genome of human.


HRP1_PLAFA Histidine-rich protein PFHRP-II (sprot)


RBP_CHICK Riboflavin-binding protein (sprot)

A protein that is a translation product of the RTBDN gene in chicken.


DYR_BOVIN Dihydrofolate reductase (sprot)

A protein that is a translation product of the DHFR gene in cow.


Q9N6S8_PLAFA Cysteine proteinase falcipain 2a (trembl)


Q9NAW2_PLAFA Cysteine proteinase falcipain 2a (trembl)


LOX15_HUMAN Polyunsaturated fatty acid lipoxygenase ALOX15 (sprot)

A polyunsaturated fatty acid lipoxygenase ALOX15 that is encoded in the genome of human.


LOX12_HUMAN Polyunsaturated fatty acid lipoxygenase ALOX12 (sprot)

A polyunsaturated fatty acid lipoxygenase ALOX12 that is encoded in the genome of human.


LX15B_HUMAN Polyunsaturated fatty acid lipoxygenase ALOX15B (sprot)

A polyunsaturated fatty acid lipoxygenase ALOX15B that is encoded in the genome of human.


LMBL3_HUMAN Lethal(3)malignant brain tumor-like protein 3 (sprot)

A lethal(3)malignant brain tumor-like protein 3 that is encoded in the genome of human.


MBTD1_HUMAN MBT domain-containing protein 1 (sprot)

An MBT domain-containing protein 1 that is encoded in the genome of human.


CRT_PLAFA Chloroquine resistance transporter (sprot)


RYR1_HUMAN Ryanodine receptor 1 (sprot)

A ryanodine receptor 1 that is encoded in the genome of human.


TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (sprot)

A transient receptor potential cation channel TRPV1 that is encoded in the genome of rat.


PDR5_YEAST Pleiotropic ABC efflux transporter of multiple drugs (sprot)

A protein that is a translation product of the PDR5 gene in yeast.


NMDZ1_RAT Glutamate receptor ionotropic, NMDA 1 (sprot)

A glutamate receptor ionotropic, NMDA 1 that is encoded in the genome of rat.


NMDE1_RAT Glutamate receptor ionotropic, NMDA 2A (sprot)

A glutamate receptor ionotropic, NMDA 2A that is encoded in the genome of rat.


NMDE2_RAT Glutamate receptor ionotropic, NMDA 2B (sprot)

A glutamate receptor ionotropic, NMDA 2B that is encoded in the genome of rat.


NMDE3_RAT Glutamate receptor ionotropic, NMDA 2C (sprot)

A glutamate receptor ionotropic, NMDA 2C that is encoded in the genome of rat.


NMDE4_RAT Glutamate receptor ionotropic, NMDA 2D (sprot)

A glutamate receptor ionotropic, NMDA 2D that is encoded in the genome of rat.


NMD3B_RAT Glutamate receptor ionotropic, NMDA 3B (sprot)

A glutamate receptor ionotropic, NMDA 3B that is encoded in the genome of rat.


NMD3A_RAT Glutamate receptor ionotropic, NMDA 3A (sprot)

A glutamate receptor ionotropic, NMDA 3A that is encoded in the genome of rat.


D4A3N4_RAT Adenylate cyclase type 1 (trembl)


Q8CFM9_RAT Adenylyl cyclase 7 (Fragment) (trembl)


ADCY3_RAT Adenylate cyclase type 3 (sprot)

An adenylate cyclase type 3 that is encoded in the genome of rat.


ADCY2_RAT Adenylate cyclase type 2 (sprot)

An adenylate cyclase type 2 that is encoded in the genome of rat.


ADCY4_RAT Adenylate cyclase type 4 (sprot)

An adenylate cyclase type 4 that is encoded in the genome of rat.


ADCY8_RAT Adenylate cyclase type 8 (sprot)

An adenylate cyclase type 8 that is encoded in the genome of rat.


ADCY6_RAT Adenylate cyclase type 6 (sprot)

An adenylate cyclase type 6 that is encoded in the genome of rat.


ADCY5_RAT Adenylate cyclase type 5 (sprot)

An adenylate cyclase type 5 that is encoded in the genome of rat.


ALR_HUMAN FAD-linked sulfhydryl oxidase ALR (sprot)

An FAD-linked sulfhydryl oxidase ALR that is encoded in the genome of human.


CALM_BOVIN Calmodulin (sprot)

A calmodulin that is encoded in the genome of cow.


PRIO_MOUSE Major prion protein (sprot)

A major prion protein that is encoded in the genome of mouse.


ASM_HUMAN Sphingomyelin phosphodiesterase (sprot)

A sphingomyelin phosphodiesterase that is encoded in the genome of human.


AT2A1_RABIT Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (sprot)


S22A6_RAT Solute carrier family 22 member 6 (sprot)

A solute carrier family 22 member 6 that is encoded in the genome of rat.


PADI4_HUMAN Protein-arginine deiminase type-4 (sprot)

A protein-arginine deiminase type-4 that is encoded in the genome of human.


NOS1_HUMAN Nitric oxide synthase 1 (sprot)

A nitric oxide synthase, brain that is encoded in the genome of human.


NOS3_HUMAN Nitric oxide synthase 3 (sprot)

A nitric oxide synthase, endothelial that is encoded in the genome of human.


NOS1_RAT Nitric oxide synthase 1 (sprot)

A nitric oxide synthase, brain that is encoded in the genome of rat.


KCNN2_RAT Small conductance calcium-activated potassium channel protein 2 (sprot)

A small conductance calcium-activated potassium channel protein 2 that is encoded in the genome of rat.


UCK1_HUMAN Uridine-cytidine kinase 1 (sprot)

A uridine-cytidine kinase 1 that is encoded in the genome of human.


KIT_HUMAN Mast/stem cell growth factor receptor Kit (sprot)

A mast/stem cell growth factor receptor that is encoded in the genome of human.


MMP3_HUMAN Stromelysin-1 (sprot)

A stromelysin-1 that is encoded in the genome of human.


MMP12_HUMAN Macrophage metalloelastase (sprot)

A macrophage metalloelastase that is encoded in the genome of human.


MMP13_HUMAN Collagenase 3 (sprot)

A collagenase 3 that is encoded in the genome of human.


MDR1A_MOUSE ATP-dependent translocase ABCB1 (sprot)

An ATP-dependent translocase ABCB1a that is encoded in the genome of mouse.


Q4QEW7_LEIMA Dihydroorotate dehydrogenase (fumarate) (trembl)


UCK2_HUMAN Uridine-cytidine kinase 2 (sprot)

A uridine-cytidine kinase 2 that is encoded in the genome of human.


PARP1_HUMAN Poly [ADP-ribose] polymerase 1 (sprot)

A poly [ADP-ribose] polymerase 1 that is encoded in the genome of human.


DOHH_HUMAN Deoxyhypusine hydroxylase (sprot)

A deoxyhypusine hydroxylase that is encoded in the genome of human.


DPEP1_HUMAN Dipeptidase 1 (sprot)

A dipeptidase 1 that is encoded in the genome of human.


DPEP1_PIG Dipeptidase 1 (sprot)

A dipeptidase 1 that is encoded in the genome of pig.


CAC1B_HUMAN Voltage-dependent N-type calcium channel subunit alpha-1B (sprot)

A voltage-dependent N-type calcium channel subunit alpha-1B that is encoded in the genome of human.


CAC1B_RAT Voltage-dependent N-type calcium channel subunit alpha-1B (sprot)

A voltage-dependent N-type calcium channel subunit alpha-1B that is encoded in the genome of rat.


HRH2_CAVPO Histamine H2 receptor (sprot)


HRH2_RAT Histamine H2 receptor (sprot)

A histamine H2 receptor that is encoded in the genome of rat.


CASR_HUMAN Extracellular calcium-sensing receptor (sprot)

An extracellular calcium-sensing receptor that is encoded in the genome of human.


GRM5_RAT Metabotropic glutamate receptor 5 (sprot)

A metabotropic glutamate receptor 5 that is encoded in the genome of rat.


Cinalukast

2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in the human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.


CLTR1_CAVPO Cysteinyl leukotriene receptor 1 (sprot)

A cysteinyl leukotriene receptor 1 that is encoded in the genome of guinea pig.


CLTR1_HUMAN Cysteinyl leukotriene receptor 1 (sprot)

A cysteinyl leukotriene receptor 1 that is encoded in the genome of human.


PARC_BACSU DNA topoisomerase 4 subunit A (sprot)


PARC_STAAU DNA topoisomerase 4 subunit A (sprot)


GYRA_MYCTU DNA gyrase subunit A (sprot)

A DNA gyrase subunit A that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


MDTK_ECOLI Multidrug resistance protein MdtK (sprot)

A multidrug resistance protein MdtK that is encoded in the genome of Escherichia coli K-12.


5HT4R_HUMAN 5-hydroxytryptamine receptor 4 (sprot)

A 5-hydroxytryptamine receptor 4 that is encoded in the genome of human.


5HT3E_HUMAN 5-hydroxytryptamine receptor 3E (sprot)

A 5-hydroxytryptamine receptor 3E that is encoded in the genome of human.


5HT3B_HUMAN 5-hydroxytryptamine receptor 3B (sprot)

A 5-hydroxytryptamine receptor 3B that is encoded in the genome of human.


5HT3D_HUMAN 5-hydroxytryptamine receptor 3D (sprot)

A 5-hydroxytryptamine receptor 3D that is encoded in the genome of human.


5HT3C_HUMAN 5-hydroxytryptamine receptor 3C (sprot)

A 5-hydroxytryptamine receptor 3C that is encoded in the genome of human.


TRPC3_HUMAN Short transient receptor potential channel 3 (sprot)

A short transient receptor potential cation channel TRPC3 that is encoded in the genome of human.


TRPC6_HUMAN Short transient receptor potential channel 6 (sprot)

A short transient receptor potential channel 6 that is encoded in the genome of human.


TRPC4_MOUSE Short transient receptor potential channel 4 (sprot)

A short transient receptor potential cation channel TRPC4 that is encoded in the genome of mouse.


TRPC5_MOUSE Short transient receptor potential channel 5 (sprot)

A short transient receptor potential channel 5 that is encoded in the genome of mouse.


TRPC7_MOUSE Short transient receptor potential channel 7 (sprot)

A short transient receptor potential cation channel TRPC7 that is encoded in the genome of mouse.


Clenbuterol

A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma.

A substituted aniline that is 2,6-dichloroaniline in which the hydrogen at position 4 has been replaced by a 2-(tert-butylamino)-1-hydroxyethyl group.


RL10_HALMA Large ribosomal subunit protein uL10 (sprot)


ADT2_HUMAN ADP/ATP translocase 2 (sprot)

An ADP/ATP translocase 2 that is encoded in the genome of human.


ADT1_HUMAN ADP/ATP translocase 1 (sprot)

An ADP/ATP translocase 1 that is encoded in the genome of human.


ADT3_HUMAN ADP/ATP translocase 3 (sprot)

An ADP/ATP translocase 3 that is encoded in the genome of human.


S17A9_HUMAN Voltage-gated purine nucleotide uniporter SLC17A9 (sprot)

A solute carrier family 17 member 9 that is encoded in the genome of human.


B1LRJ1_ECOSM Type IV secretion-like conjugative transfer relaxase protein TraI (trembl)


DPOLA_HUMAN DNA polymerase alpha catalytic subunit (sprot)

A DNA polymerase alpha catalytic subunit that is encoded in the genome of human.


RIR1_HUMAN Ribonucleoside-diphosphate reductase large subunit (sprot)

A ribonucleoside-diphosphate reductase large subunit that is encoded in the genome of human.


RIR2_HUMAN Ribonucleoside-diphosphate reductase subunit M2 (sprot)

A ribonucleoside-diphosphate reductase subunit M2 that is encoded in the genome of human.


PRPS1_HUMAN Ribose-phosphate pyrophosphokinase 1 (sprot)

A ribose-phosphate pyrophosphokinase 1 that is encoded in the genome of human.


CZCO_GEOKA Uncharacterized oxidoreductase CzcO-like (sprot)


Clofibric acid

An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.

A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.


PPARA_MOUSE Peroxisome proliferator-activated receptor alpha (sprot)

A peroxisome proliferator-activated receptor alpha that is encoded in the genome of mouse.


PTGDS_MOUSE Prostaglandin-H2 D-isomerase (sprot)

A prostaglandin-H2 D-isomerase that is encoded in the genome of mouse.


GSTP1_HUMAN Glutathione S-transferase P (sprot)

A glutathione S-transferase P that is encoded in the genome of human.


TYTR_TRYBB Trypanothione reductase (sprot)


GBRP_HUMAN Gamma-aminobutyric acid receptor subunit pi (sprot)

A gamma-aminobutyric acid receptor subunit pi that is encoded in the genome of human.


GBRE_HUMAN Gamma-aminobutyric acid receptor subunit epsilon (sprot)

A gamma-aminobutyric acid receptor subunit epsilon that is encoded in the genome of human.


GBRT_HUMAN Gamma-aminobutyric acid receptor subunit theta (sprot)

A gamma-aminobutyric acid receptor subunit theta that is encoded in the genome of human.


NISCH_RAT Nischarin (sprot)

A nischarin that is encoded in the genome of rat.


HCN1_MOUSE Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 that is encoded in the genome of mouse.


HCN2_MOUSE Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 that is encoded in the genome of mouse.


HCN4_MOUSE Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 that is encoded in the genome of mouse.


Clonixin

A pyridinemonocarboxylic acid that is nicotinic acid substituted at position 2 by a (2-methyl-3-chlorophenyl)amino group. Used (as its lysine salt) for treatment of renal colic, muscular pain and moderately severe migraine attacks.


P2Y12_HUMAN P2Y purinoceptor 12 (sprot)

A P2Y purinoceptor 12 that is encoded in the genome of human.


CP2B6_HUMAN Cytochrome P450 2B6 (sprot)

A cytochrome P450 2B6 that is encoded in the genome of human.


Clorprenaline

A racemate comprise of equimolar amounts of (R)- and (S)-clorprenaline. It is a beta2-adrenergic receptor agonist and a bronchodilator.


KCNA3_HUMAN Potassium voltage-gated channel subfamily A member 3 (sprot)

A voltage-gated potassium channel subunit KCNA3 that is encoded in the genome of human.


NR1H4_HUMAN Bile acid receptor (sprot)

A bile acid receptor that is encoded in the genome of human.


CP51_MYCTU Sterol 14alpha-demethylase (sprot)

A protein that is a translation product of the cyp51 gene in Mycobacterium tuberculosis H37Rv.


CXCR1_HUMAN C-X-C chemokine receptor type 1 (sprot)

A C-X-C chemokine receptor type 1 that is encoded in the genome of human.


CP51A_ASPFU Sterol 14-alpha demethylase cyp51A (sprot)


Q96W81_ASPFM 14-alpha sterol demethylase (trembl)

A protein that is a translation product of the cyp51B gene in Neosartorya fumigata.


I23O2_MOUSE Indoleamine 2,3-dioxygenase 2 (sprot)

An indoleamine 2,3-dioxygenase 2 that is encoded in the genome of mouse.


CP121_MYCTU Mycocyclosin synthase (sprot)

A protein that is a translation product of the cyp121 gene in Mycobacterium tuberculosis H37Rv.


TERA_HUMAN Transitional endoplasmic reticulum ATPase (sprot)

A transitional endoplasmic reticulum ATPase that is encoded in the genome of human.


MDHC_HUMAN Malate dehydrogenase, cytoplasmic (sprot)

A malate dehydrogenase, cytoplasmic that is encoded in the genome of human.


CP130_MYCTU Cytochrome P450 130 (sprot)

A protein that is a translation product of the cyp130 gene in Mycobacterium tuberculosis H37Rv.


I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 (sprot)

An indoleamine 2,3-dioxygenase 1 that is encoded in the genome of mouse.


CP8B1_HUMAN 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (sprot)

A cytochrome P450 8B1 that is encoded in the genome of human.


P72355_STAAU Penicillin-binding protein 4 (trembl)


Q53707_STAAU MecA PBP2' (penicillin binding protein 2') (trembl)


Q53725_STAAU Cell division protein FtsI (Peptidoglycan synthetase) (trembl)


Q53729_STAAU Penicillin-binding protein 2 (trembl)


Q9XDB3_STAAU Cell division protein FtsI [Peptidoglycan synthetase] / Transpeptidase, Penicillin binding protein transpeptidase domain, Penicillin-binding protein 3 (trembl)


UD14_HUMAN UDP-glucuronosyltransferase 1A4 (sprot)

A UDP-glucuronosyltransferase 1A4 that is encoded in the genome of human.


DRD2_MOUSE D(2) dopamine receptor (sprot)

A D(2) dopamine receptor that is encoded in the genome of mouse.


5HT1A_MOUSE 5-hydroxytryptamine receptor 1A (sprot)

A 5-hydroxytryptamine receptor 1A that is encoded in the genome of mouse.


DRD2_CHLAE D(2) dopamine receptor (sprot)


5HT3A_MOUSE 5-hydroxytryptamine receptor 3A (sprot)

A 5-hydroxytryptamine receptor 3A that is encoded in the genome of mouse.


DRD1_PIG D(1A) dopamine receptor (sprot)

A D(1A) dopamine receptor that is encoded in the genome of pig.


DRD3_CHLAE D(3) dopamine receptor (sprot)


HRH4_MOUSE Histamine H4 receptor (sprot)

An H4 histamine receptor that is encoded in the genome of mouse.


HRH4_RAT Histamine H4 receptor (sprot)

An H4 histamine receptor that is encoded in the genome of rat.


5HT2C_MOUSE 5-hydroxytryptamine receptor 2C (sprot)

A 5-hydroxytryptamine receptor 2C that is encoded in the genome of mouse.


5HT2A_MOUSE 5-hydroxytryptamine receptor 2A (sprot)

A 5-hydroxytryptamine receptor 2A that is encoded in the genome of mouse.


5HT2B_MOUSE 5-hydroxytryptamine receptor 2B (sprot)

A 5-hydroxytryptamine receptor 2B that is encoded in the genome of mouse.


5HT5A_MOUSE 5-hydroxytryptamine receptor 5A (sprot)

A 5-hydroxytryptamine receptor 5A that is encoded in the genome of mouse.


SC6A3_BOVIN Sodium-dependent dopamine transporter (sprot)


SC6A3_MACFA Sodium-dependent dopamine transporter (sprot)

A sodium-dependent dopamine transporter that is encoded in the genome of Macaca fascicularis.


GLRA2_HUMAN Glycine receptor subunit alpha-2 (sprot)

A glycine receptor subunit alpha-2 that is encoded in the genome of human.


TBB5_HUMAN Tubulin beta chain (sprot)

A tubulin beta chain that is encoded in the genome of human.


PIM1_HUMAN Serine/threonine-protein kinase pim-1 (sprot)

A proto-oncogene serine/threonine-protein kinase Pim-1 that is encoded in the genome of human.


TBA1A_PIG Tubulin alpha-1A chain (sprot)


TBB2B_BOVIN Tubulin beta-2B chain (sprot)

A protein that is a translation product of the TUBB2B gene in cow.


TPPP_BOVIN Tubulin polymerization-promoting protein (sprot)

A tubulin polymerization-promoting protein that is encoded in the genome of cow.


Q862F3_BOVIN Similar to alpha-tubulin isoform 1 (Fragment) (trembl)


Q862L2_BOVIN Similar to alpha-tubulin isoform 1 (Fragment) (trembl)


Colforsin daropate

Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant COLEUS FORSKOHLII. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities; also lowers intraocular pressure and promotes release of hormones from the pituitary gland.

A carboxylic ester resuting from the formal condensation of the carboxy group of N,N-dimethyl-beta-alanine with the 6-hydroxy group of forskolin. It is an adenylate cyclase activator.


ADCY1_HUMAN Adenylate cyclase type 1 (sprot)

An adenylate cyclase type 1 that is encoded in the genome of human.


GTR1_HUMAN Solute carrier family 2, facilitated glucose transporter member 1 (sprot)

A solute carrier family 2, facilitated glucose transporter member 1 that is encoded in the genome of human.


ADCY1_BOVIN Adenylate cyclase type 1 (sprot)

An adenylate cyclase type 1 that is encoded in the genome of cow.


ADCY8_HUMAN Adenylate cyclase type 8 (sprot)

An adenylate cyclase type 8 that is encoded in the genome of human.


OXYR_RAT Oxytocin receptor (sprot)

An oxytocin receptor that is encoded in the genome of rat.


V2R_RAT Vasopressin V2 receptor (sprot)

A vasopressin V2 receptor that is encoded in the genome of rat.


V1AR_RAT Vasopressin V1a receptor (sprot)

A vasopressin V1a receptor that is encoded in the genome of rat.


KCNA1_HUMAN Potassium voltage-gated channel subfamily A member 1 (sprot)

A voltage-gated potassium channel subunit KCNA1 that is encoded in the genome of human.


FNTA_HUMAN Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (sprot)

A protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha that is encoded in the genome of human.


Cotinine

The N-glucuronide conjugate of cotinine is a major urinary metabolite of NICOTINE. It thus serves as a biomarker of exposure to tobacco SMOKING. It has CNS stimulating properties.

An N-alkylpyrrolidine that consists of N-methylpyrrolidinone bearing a pyridin-3-yl substituent at position C-5 (the 5S-enantiomer). It is an alkaloid commonly found in Nicotiana tabacum.


Coumarin

effective in reducing edema following crush & thermal injury; structure in Merck Index, 9th ed, #2547; Coumarin itself occurs in the Tonka bean

A chromenone having the keto group located at the 2-position.


MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (sprot)

An induced myeloid leukemia cell differentiation protein Mcl-1 that is encoded in the genome of human.


SETD7_HUMAN Histone-lysine N-methyltransferase SETD7 (sprot)

A histone-lysine N-methyltransferase SETD7 that is encoded in the genome of human.


PPAP_HUMAN Prostatic acid phosphatase (sprot)

A prostatic acid phosphatase that is encoded in the genome of human.


DPOLB_HUMAN DNA polymerase beta (sprot)

A DNA polymerase beta that is encoded in the genome of human.


DPOD1_HUMAN DNA polymerase delta catalytic subunit (sprot)

A DNA polymerase delta catalytic subunit that is encoded in the genome of human.


DPOE1_HUMAN DNA polymerase epsilon catalytic subunit A (sprot)

A DNA polymerase epsilon catalytic subunit A that is encoded in the genome of human.


DPOA2_HUMAN DNA polymerase alpha subunit B (sprot)

A DNA polymerase alpha subunit B that is encoded in the genome of human.


GRB2_HUMAN Growth factor receptor-bound protein 2 (sprot)

A growth factor receptor-bound protein 2 that is encoded in the genome of human.


DDR2_HUMAN Discoidin domain-containing receptor 2 (sprot)

A discoidin domain-containing receptor 2 that is encoded in the genome of human.


GRB2_MOUSE Growth factor receptor-bound protein 2 (sprot)

A growth factor receptor-bound protein 2 that is encoded in the genome of mouse.


NGLY1_HUMAN Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (sprot)

A peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase that is encoded in the genome of human.


PROC_HUMAN Vitamin K-dependent protein C (sprot)

A vitamin K-dependent protein C that is encoded in the genome of human.


TRY2_HUMAN Trypsin-2 (sprot)

A trypsin-2 that is encoded in the genome of human.


TRY3_HUMAN Trypsin-3 (sprot)

A trypsin-3 that is encoded in the genome of human.


Q28731_RABIT Thrombin (Fragment) (trembl)


STS_HUMAN Steryl-sulfatase (sprot)

A steryl-sulfatase that is encoded in the genome of human.


RYR3_HUMAN Ryanodine receptor 3 (sprot)

A ryanodine receptor 3 that is encoded in the genome of human.


CISD1_HUMAN CDGSH iron-sulfur domain-containing protein 1 (sprot)

A CDGSH iron-sulfur domain-containing protein 1 that is encoded in the genome of human.


AOFB_RAT Amine oxidase [flavin-containing] B (sprot)

An amine oxidase [flavin-containing] B that is encoded in the genome of rat.


Q33BM1_RAT G protein-coupled receptor GPR35 (trembl)


GPR35_MOUSE G-protein coupled receptor 35 (sprot)

A G-protein coupled receptor 35 that is encoded in the genome of mouse.


S100P_HUMAN Protein S100-P (sprot)

A protein S100-P that is encoded in the genome of human.


Cyclofenil

A gonadal stimulant and inducer of ovulation. It is used in the treatment of infertility and amenorrhea, but is thought to be less effective than CLOMIPHENE.


Cycloguanil

the active metabolite of proguanil; antifolate drug

A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil.


DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)


DDL_MYCTU D-alanine--D-alanine ligase (sprot)

A D-alanine--D-alanine ligase A that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


ALR_MYCTU Alanine racemase (sprot)

A protein that is a translation product of the alr gene in Mycobacterium tuberculosis H37Rv.


FKB1A_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP1A (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP1A that is encoded in the genome of human.


PPIA_HUMAN Peptidyl-prolyl cis-trans isomerase A (sprot)

A peptidyl-prolyl cis-trans isomerase A that is encoded in the genome of human.


FPR1_HUMAN fMet-Leu-Phe receptor (sprot)

An fMet-Leu-Phe receptor that is encoded in the genome of human.


SO1B1_HUMAN Solute carrier organic anion transporter family member 1B1 (sprot)

A solute carrier organic anion transporter family member 1B1 that is encoded in the genome of human.


FKBP4_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP4 (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP4 that is encoded in the genome of human.


PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B (sprot)

A eukaryotic peptidyl-prolyl cis-trans isomerase B that is encoded in the genome of human.


PP2BA_HUMAN Protein phosphatase 3 catalytic subunit alpha (sprot)

A protein phosphatase 3 catalytic subunit alpha that is encoded in the genome of human.


FKB1B_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP1B (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP1B that is encoded in the genome of human.


PPID_HUMAN Peptidyl-prolyl cis-trans isomerase D (sprot)

A eukaryotic-type peptidyl-prolyl cis-trans isomerase D that is encoded in the genome of human.


SO1B3_HUMAN Solute carrier organic anion transporter family member 1B3 (sprot)

A solute carrier organic anion transporter family member 1B3 that is encoded in the genome of human.


NTCP_HUMAN Hepatic sodium/bile acid cotransporter (sprot)

A hepatic sodium/bile acid cotransporter that is encoded in the genome of human.


PK3CG_MOUSE Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (sprot)

A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform that is encoded in the genome of mouse.


Cyclothiazide

inhibits the desensitization of AMPA-type receptors; structure

3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.


GRIA1_HUMAN Glutamate receptor 1 (sprot)

A glutamate receptor 1 that is encoded in the genome of human.


GRIA2_HUMAN Glutamate receptor 2 (sprot)

A glutamate receptor 2 that is encoded in the genome of human.


GRIA4_HUMAN Glutamate receptor 4 (sprot)

A glutamate receptor 4 that is encoded in the genome of human.


GRIA3_HUMAN Glutamate receptor 3 (sprot)

A glutamate receptor 3 that is encoded in the genome of human.


GRIA1_RAT Glutamate receptor 1 (sprot)

A glutamate receptor 1 that is encoded in the genome of rat.


GRIA2_RAT Glutamate receptor 2 (sprot)

A glutamate receptor 2 that is encoded in the genome of rat.


GRIA3_RAT Glutamate receptor 3 (sprot)

A glutamate receptor 3 that is encoded in the genome of rat.


GRIA4_RAT Glutamate receptor 4 (sprot)

A glutamate receptor 4 that is encoded in the genome of rat.


Q7ZJM1_9HIV1 Integrase (Fragment) (trembl)


JUN_HUMAN Transcription factor Jun (sprot)

A transcription factor Jun that is encoded in the genome of human.


DEPTROPINE

minor descriptor (65-85); on-line & Index Medicus search TROPANES (66-85); RN given refers to parent cpd

An azabicycloalkane that is the 10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl ether of tropine.


Q8WSF8_APLCA Soluble acetylcholine receptor (trembl)


KCNK9_HUMAN Potassium channel subfamily K member 9 (sprot)

A potassium channel subfamily K member 9 that is encoded in the genome of human.


KCNKI_HUMAN Potassium channel subfamily K member 18 (sprot)

A potassium channel subfamily K member 18 that is encoded in the genome of human.


GLRB_HUMAN Glycine receptor subunit beta (sprot)

A glycine receptor subunit beta that is encoded in the genome of human.


S29A4_HUMAN Equilibrative nucleoside transporter 4 (sprot)

An equilibrative nucleoside transporter 4 that is encoded in the genome of human.


KCNJ5_MOUSE G protein-activated inward rectifier potassium channel 4 (sprot)

A G protein-activated inward rectifier potassium channel 4 that is encoded in the genome of mouse.


Deslanoside

Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.

A cardenolide glycoside that is lanatoside C with the acetoxy group replaced by a hydroxy group.


GBRR2_HUMAN Gamma-aminobutyric acid receptor subunit rho-2 (sprot)

A gamma-aminobutyric acid receptor subunit rho-2 that is encoded in the genome of human.


A2AMW3_MOUSE Gamma-aminobutyric acid (GABA) A receptor, subunit epsilon (trembl)


GBRA6_MOUSE Gamma-aminobutyric acid receptor subunit alpha-6 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-6 that is encoded in the genome of mouse.


GBRG2_MOUSE Gamma-aminobutyric acid receptor subunit gamma-2 (sprot)

A gamma-aminobutyric acid receptor subunit gamma-2 that is encoded in the genome of mouse.


GBRD_MOUSE Gamma-aminobutyric acid receptor subunit delta (sprot)

A gamma-aminobutyric acid receptor subunit delta that is encoded in the genome of mouse.


GBRA2_MOUSE Gamma-aminobutyric acid receptor subunit alpha-2 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-2 that is encoded in the genome of mouse.


GBRA3_MOUSE Gamma-aminobutyric acid receptor subunit alpha-3 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-3 that is encoded in the genome of mouse.


GBRG3_MOUSE Gamma-aminobutyric acid receptor subunit gamma-3 (sprot)

A gamma-aminobutyric acid receptor subunit gamma-3 that is encoded in the genome of mouse.


GBRB1_MOUSE Gamma-aminobutyric acid receptor subunit beta-1 (sprot)

A gamma-aminobutyric acid receptor subunit beta-1 that is encoded in the genome of mouse.


GBRA1_MOUSE Gamma-aminobutyric acid receptor subunit alpha-1 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-1 that is encoded in the genome of mouse.


GBRB3_MOUSE Gamma-aminobutyric acid receptor subunit beta-3 (sprot)

A gamma-aminobutyric acid receptor subunit beta-3 that is encoded in the genome of mouse.


GBRA5_MOUSE Gamma-aminobutyric acid receptor subunit alpha-5 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-5 that is encoded in the genome of mouse.


GBRP_MOUSE Gamma-aminobutyric acid receptor subunit pi (sprot)

A gamma-aminobutyric acid receptor subunit pi that is encoded in the genome of mouse.


GBRA4_MOUSE Gamma-aminobutyric acid receptor subunit alpha-4 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-4 that is encoded in the genome of mouse.


GBRT_MOUSE Gamma-aminobutyric acid receptor subunit theta (sprot)

A gamma-aminobutyric acid receptor subunit theta that is encoded in the genome of mouse.


GBRG1_MOUSE Gamma-aminobutyric acid receptor subunit gamma-1 (sprot)

A gamma-aminobutyric acid receptor subunit gamma-1 that is encoded in the genome of mouse.


V1BR_HUMAN Vasopressin V1b receptor (sprot)

A vasopressin V1b receptor that is encoded in the genome of human.


V1BR_RAT Vasopressin V1b receptor (sprot)

A vasopressin V1b receptor that is encoded in the genome of rat.


Desoxycortone

A steroid metabolite that is the 11-deoxy derivative of CORTICOSTERONE and the 21-hydroxy derivative of PROGESTERONE

A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group.


Deoxycorticosterone acetate

The 21-acetate derivative of desoxycorticosterone.


IL4_HUMAN Interleukin-4 (sprot)

An interleukin-4 that is encoded in the genome of human.


DHPS1_MYCLE Dihydropteroate synthase (sprot)

A dihydropteroate synthase that is encoded in the genome of Mycobacterium leprae TN.


G6PD_HUMAN Glucose-6-phosphate 1-dehydrogenase (sprot)

A glucose-6-phosphate 1-dehydrogenase that is encoded in the genome of human.


OMPD_SALCH Outer membrane porin protein OmpD (sprot)


JAK3_HUMAN Tyrosine-protein kinase JAK3 (sprot)

A tyrosine-protein kinase JAK3 that is encoded in the genome of human.


PGFRB_HUMAN Platelet-derived growth factor receptor beta (sprot)

A beta-type platelet-derived growth factor receptor that is encoded in the genome of human.


ABL1_HUMAN Tyrosine-protein kinase ABL1 (sprot)

A tyrosine-protein kinase ABL1 that is encoded in the genome of human.


MTOR_HUMAN Serine/threonine-protein kinase mTOR (sprot)

A serine/threonine-protein kinase mTOR that is encoded in the genome of human.


BCR_HUMAN Breakpoint cluster region protein (sprot)

A breakpoint cluster region protein that is encoded in the genome of human.


YES_HUMAN Tyrosine-protein kinase Yes (sprot)

A tyrosine-protein kinase Yes that is encoded in the genome of human.


EPHA2_HUMAN Ephrin type-A receptor 2 (sprot)

An ephrin type-A receptor 2 that is encoded in the genome of human.


RAF1_HUMAN RAF proto-oncogene serine/threonine-protein kinase (sprot)

A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of human.


BRAF_HUMAN Serine/threonine-protein kinase B-raf (sprot)

A B-Raf proto-oncogene serine/threonine-protein kinase that is encoded in the genome of human.


FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 (sprot)

A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of human.


VGFR1_HUMAN Vascular endothelial growth factor receptor 1 (sprot)

A vascular endothelial growth factor receptor 1 that is encoded in the genome of human.


VGFR2_HUMAN Vascular endothelial growth factor receptor 2 (sprot)

A vascular endothelial growth factor receptor 2 that is encoded in the genome of human.


CSF1R_HUMAN Macrophage colony-stimulating factor 1 receptor (sprot)

A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of human.


PGFRA_HUMAN Platelet-derived growth factor receptor alpha (sprot)

An alpha-type platelet-derived growth factor receptor that is encoded in the genome of human.


MYLK_HUMAN Myosin light chain kinase, smooth muscle (sprot)

A myosin light chain kinase, smooth muscle that is encoded in the genome of human.


FGFR3_HUMAN Fibroblast growth factor receptor 3 (sprot)

A fibroblast growth factor receptor 3 that is encoded in the genome of human.


HCK_HUMAN Tyrosine-protein kinase HCK (sprot)

A tyrosine-protein kinase HCK that is encoded in the genome of human.


ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 (sprot)

A receptor tyrosine-protein kinase erbB-4 that is encoded in the genome of human.


KAPCB_HUMAN cAMP-dependent protein kinase catalytic subunit beta (sprot)

A cAMP-dependent protein kinase catalytic subunit beta that is encoded in the genome of human.


KSYK_HUMAN Tyrosine-protein kinase SYK (sprot)

A tyrosine-protein kinase SYK that is encoded in the genome of human.


MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardiac muscle (sprot)

A myosin light chain kinase 2, skeletal/cardiac muscle that is encoded in the genome of human.


CSK_HUMAN Tyrosine-protein kinase CSK (sprot)

A tyrosine-protein kinase CSK that is encoded in the genome of human.


EPHA8_HUMAN Ephrin type-A receptor 8 (sprot)

An ephrin type-A receptor 8 that is encoded in the genome of human.


LYN_HUMAN Tyrosine-protein kinase Lyn (sprot)

A tyrosine-protein kinase Lyn that is encoded in the genome of human.


BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX (sprot)

A cytoplasmic tyrosine-protein kinase BMX that is encoded in the genome of human.


NEK2_HUMAN Serine/threonine-protein kinase Nek2 (sprot)

A serine/threonine-protein kinase Nek2 that is encoded in the genome of human.


LIMK1_HUMAN LIM domain kinase 1 (sprot)

A LIM domain kinase 1 that is encoded in the genome of human.


FGFR1_HUMAN Fibroblast growth factor receptor 1 (sprot)

A fibroblast growth factor receptor 1 that is encoded in the genome of human.


STK10_HUMAN Serine/threonine-protein kinase 10 (sprot)

A serine/threonine-protein kinase 10 that is encoded in the genome of human.


MK11_HUMAN Mitogen-activated protein kinase 11 (sprot)

A mitogen-activated protein kinase 11 that is encoded in the genome of human.


EPHA5_HUMAN Ephrin type-A receptor 5 (sprot)

An ephrin type-A receptor 5 that is encoded in the genome of human.


EPHA4_HUMAN Ephrin type-A receptor 4 (sprot)

An ephrin type-A receptor 4 that is encoded in the genome of human.


FGFR2_HUMAN Fibroblast growth factor receptor 2 (sprot)

A fibroblast growth factor receptor 2 that is encoded in the genome of human.


PKN1_HUMAN Serine/threonine-protein kinase N1 (sprot)

A serine/threonine-protein kinase N1 that is encoded in the genome of human.


KPCT_HUMAN Protein kinase C theta type (sprot)

A protein kinase C theta type that is encoded in the genome of human.


EPHA6_HUMAN Ephrin type-A receptor 6 (sprot)

An ephrin type-A receptor 6 that is encoded in the genome of human.


TNIK_HUMAN TRAF2 and NCK-interacting protein kinase (sprot)

A TRAF2 and NCK-interacting protein kinase that is encoded in the genome of human.


KC1E_HUMAN Casein kinase I isoform epsilon (sprot)

A casein kinase I isoform epsilon that is encoded in the genome of human.


FGR_HUMAN Tyrosine-protein kinase Fgr (sprot)

A tyrosine-protein kinase Fgr that is encoded in the genome of human.


AURKA_HUMAN Aurora kinase A (sprot)

An aurora kinase A that is encoded in the genome of human.


STK36_HUMAN Serine/threonine-protein kinase 36 (sprot)

A serine/threonine-protein kinase 36 that is encoded in the genome of human.


EPHA3_HUMAN Ephrin type-A receptor 3 (sprot)

An ephrin type-A receptor 3 that is encoded in the genome of human.


FRK_HUMAN Tyrosine-protein kinase FRK (sprot)

A tyrosine-protein kinase FRK that is encoded in the genome of human.


M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 5 that is encoded in the genome of human.


M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 (sprot)

A mitogen-activated protein kinase kinase kinase 4 that is encoded in the genome of human.


GAK_HUMAN Cyclin-G-associated kinase (sprot)

A cyclin-G-associated kinase that is encoded in the genome of human.


RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 (sprot)

A receptor-interacting serine/threonine-protein kinase 2 that is encoded in the genome of human.


EPHB1_HUMAN Ephrin type-B receptor 1 (sprot)

An ephrin type-B receptor 1 that is encoded in the genome of human.


STK4_HUMAN Serine/threonine-protein kinase 4 (sprot)

A serine/threonine-protein kinase 4 that is encoded in the genome of human.


ACK1_HUMAN Activated CDC42 kinase 1 (sprot)

An activated CDC42 kinase 1 that is encoded in the genome of human.


SLK_HUMAN STE20-like serine/threonine-protein kinase (sprot)

A STE20-like serine/threonine-protein kinase that is encoded in the genome of human.


DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 (sprot)

A discoidin domain-containing receptor 1 that is encoded in the genome of human.


EPHB4_HUMAN Ephrin type-B receptor 4 (sprot)

An ephrin type-B receptor 4 that is encoded in the genome of human.


ACV1B_HUMAN Activin receptor type-1B (sprot)

An activin receptor type-1B that is encoded in the genome of human.


ACVL1_HUMAN Serine/threonine-protein kinase receptor R3 (sprot)

A serine/threonine-protein kinase receptor R3 that is encoded in the genome of human.


ACVR1_HUMAN Activin receptor type-1 (sprot)

An activin receptor type-1 that is encoded in the genome of human.


TGFR2_HUMAN TGF-beta receptor type-2 (sprot)

A TGF-beta receptor type-2 that is encoded in the genome of human.


MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 (sprot)

A dual specificity mitogen-activated protein kinase kinase 1 that is encoded in the genome of human.


MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 (sprot)

A dual specificity mitogen-activated protein kinase kinase 2 that is encoded in the genome of human.


ITK_HUMAN Tyrosine-protein kinase ITK/TSK (sprot)

A tyrosine-protein kinase ITK/TSK that is encoded in the genome of human.


PTK6_HUMAN Protein-tyrosine kinase 6 (sprot)

A protein-tyrosine kinase 6 that is encoded in the genome of human.


LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK (sprot)

A tyrosine-protein kinase Lck that is encoded in the genome of mouse.


BTK_HUMAN Tyrosine-protein kinase BTK (sprot)

A tyrosine-protein kinase BTK that is encoded in the genome of human.


TEC_HUMAN Tyrosine-protein kinase Tec (sprot)

A tyrosine-protein kinase Tec that is encoded in the genome of human.


EPHB2_HUMAN Ephrin type-B receptor 2 (sprot)

An ephrin type-B receptor 2 that is encoded in the genome of human.


TNK1_HUMAN Non-receptor tyrosine-protein kinase TNK1 (sprot)

A non-receptor tyrosine-protein kinase TNK1 that is encoded in the genome of human.


TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 (sprot)

A non-receptor tyrosine-protein kinase TYK2 that is encoded in the genome of human.


PK3CA_HUMAN Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (sprot)

A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of human.


SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (sprot)

A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of chicken.


WEE1_HUMAN Wee1-like protein kinase (sprot)

A Wee1-like protein kinase that is encoded in the genome of human.


STK25_HUMAN Serine/threonine-protein kinase 25 (sprot)

A serine/threonine-protein kinase 25 that is encoded in the genome of human.


M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 (sprot)

A mitogen-activated protein kinase kinase kinase 20 that is encoded in the genome of human.


TXK_HUMAN Tyrosine-protein kinase TXK (sprot)

A tyrosine-protein kinase TXK that is encoded in the genome of human.


LIMK2_HUMAN LIM domain kinase 2 (sprot)

A LIM domain kinase 2 that is encoded in the genome of human.


STK26_HUMAN Serine/threonine-protein kinase 26 (sprot)

A serine/threonine-protein kinase 26 that is encoded in the genome of human.


NLK_HUMAN Serine/threonine-protein kinase NLK (sprot)

A serine/threonine-protein kinase NLK that is encoded in the genome of human.


E2AK4_HUMAN eIF-2-alpha kinase GCN2 (sprot)

An eIF-2-alpha kinase GCN2 that is encoded in the genome of human.


SIK2_HUMAN Serine/threonine-protein kinase SIK2 (sprot)

A serine/threonine-protein kinase SIK2 that is encoded in the genome of human.


AVR2A_HUMAN Activin receptor type-2A (sprot)

An activin receptor type-2A that is encoded in the genome of human.


AVR2B_HUMAN Activin receptor type-2B (sprot)

An activin receptor type-2B that is encoded in the genome of human.


TNI3K_HUMAN Serine/threonine-protein kinase TNNI3K (sprot)

A serine/threonine-protein kinase TNNI3K that is encoded in the genome of human.


DMPK_HUMAN Myotonin-protein kinase (sprot)

A myotonin-protein kinase that is encoded in the genome of human.


COQ8A_HUMAN Atypical kinase COQ8A, mitochondrial (sprot)

An atypical kinase COQ8A, mitochondrial that is encoded in the genome of human.


MRCKG_HUMAN Serine/threonine-protein kinase MRCK gamma (sprot)

A serine/threonine-protein kinase MRCK gamma that is encoded in the genome of human.


M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 1 that is encoded in the genome of human.


PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (sprot)

A membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase that is encoded in the genome of human.


M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 3 that is encoded in the genome of human.


AURKB_HUMAN Aurora kinase B (sprot)

An aurora kinase B that is encoded in the genome of human.


BLK_HUMAN Tyrosine-protein kinase Blk (sprot)

A tyrosine-protein kinase BLK that is encoded in the genome of human.


BMR1A_HUMAN Bone morphogenetic protein receptor type-1A (sprot)

A BMP receptor type-1A that is encoded in the genome of human.


M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 4 that is encoded in the genome of human.


MRCKA_HUMAN Serine/threonine-protein kinase MRCK alpha (sprot)

A serine/threonine-protein kinase MRCK alpha that is encoded in the genome of human.


MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta (sprot)

A serine/threonine-protein kinase MRCK beta that is encoded in the genome of human.


PAK4_HUMAN Serine/threonine-protein kinase PAK 4 (sprot)

A serine/threonine-protein kinase PAK 4 that is encoded in the genome of human.


SIK1_HUMAN Serine/threonine-protein kinase SIK1 (sprot)

A serine/threonine-protein kinase SIK1 that is encoded in the genome of human.


SRMS_HUMAN Tyrosine-protein kinase Srms (sprot)

A tyrosine-protein kinase Srms that is encoded in the genome of human.


TESK1_HUMAN Dual specificity testis-specific protein kinase 1 (sprot)

A dual specificity testis-specific protein kinase 1 that is encoded in the genome of human.


TGFR1_HUMAN TGF-beta receptor type-1 (sprot)

A TGF-beta receptor type-1 that is encoded in the genome of human.


EPHA1_HUMAN Ephrin type-A receptor 1 (sprot)

An ephrin type-A receptor 1 that is encoded in the genome of human.


EPHB3_HUMAN Ephrin type-B receptor 3 (sprot)

An ephrin type-B receptor 3 that is encoded in the genome of human.


TBA1A_RAT Tubulin alpha-1A chain (sprot)

A protein that is a translation product of the Tuba1a gene in rat.


M4K2_HUMAN Mitogen-activated protein kinase kinase kinase kinase 2 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 2 that is encoded in the genome of human.


MINK1_HUMAN Misshapen-like kinase 1 (sprot)

A misshapen-like kinase 1 that is encoded in the genome of human.


BLK_MOUSE Tyrosine-protein kinase Blk (sprot)

A tyrosine-protein kinase BLK that is encoded in the genome of mouse.


EPHB6_HUMAN Ephrin type-B receptor 6 (sprot)

An ephrin type-B receptor 6 that is encoded in the genome of human.


M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 (sprot)

A mitogen-activated protein kinase kinase kinase 13 that is encoded in the genome of human.


M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 (sprot)

A mitogen-activated protein kinase kinase kinase 2 that is encoded in the genome of human.


M3K3_HUMAN Mitogen-activated protein kinase kinase kinase 3 (sprot)

A mitogen-activated protein kinase kinase kinase 3 that is encoded in the genome of human.


TAOK3_HUMAN Serine/threonine-protein kinase TAO3 (sprot)

A serine/threonine-protein kinase TAO3 that is encoded in the genome of human.


ULK3_HUMAN Serine/threonine-protein kinase ULK3 (sprot)

A serine/threonine-protein kinase ULK3 that is encoded in the genome of human.


M3K19_HUMAN Mitogen-activated protein kinase kinase kinase 19 (sprot)

A mitogen-activated protein kinase kinase kinase 19 that is encoded in the genome of human.


STK35_HUMAN Serine/threonine-protein kinase 35 (sprot)

A serine/threonine-protein kinase 35 that is encoded in the genome of human.


ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 (sprot)

A receptor tyrosine-protein kinase erbB-3 that is encoded in the genome of human.


M3K1_HUMAN Mitogen-activated protein kinase kinase kinase 1 (sprot)

A mitogen-activated protein kinase kinase kinase 1 that is encoded in the genome of human.


SIK3_HUMAN Serine/threonine-protein kinase SIK3 (sprot)

A serine/threonine-protein kinase QSK that is encoded in the genome of human.


WEE2_HUMAN Wee1-like protein kinase 2 (sprot)

A Wee1-like protein kinase 2 that is encoded in the genome of human.


BMR1B_HUMAN Bone morphogenetic protein receptor type-1B (sprot)

A BMP receptor type-1B that is encoded in the genome of human.


NORA_STAAU Quinolone resistance protein NorA (sprot)


SBK1_HUMAN Serine/threonine-protein kinase SBK1 (sprot)

A serine/threonine-protein kinase SBK1 that is encoded in the genome of human.


VRK2_HUMAN Serine/threonine-protein kinase VRK2 (sprot)

A serine/threonine-protein kinase VRK2 that is encoded in the genome of human.


TAOK2_HUMAN Serine/threonine-protein kinase TAO2 (sprot)

A serine/threonine-protein kinase TAO2 that is encoded in the genome of human.


MP2K5_HUMAN Dual specificity mitogen-activated protein kinase kinase 5 (sprot)

A dual specificity mitogen-activated protein kinase kinase 5 that is encoded in the genome of human.


NEK11_HUMAN Serine/threonine-protein kinase Nek11 (sprot)

A serine/threonine-protein kinase Nek11 that is encoded in the genome of human.


CDPK1_PLAF7 Calcium-dependent protein kinase 1 (sprot)

A protein that is a translation product of the CPK1 gene in Plasmodium falciparum 3D7.


MK13_HUMAN Mitogen-activated protein kinase 13 (sprot)

A mitogen-activated protein kinase 13 that is encoded in the genome of human.


MK12_HUMAN Mitogen-activated protein kinase 12 (sprot)

A mitogen-activated protein kinase 12 that is encoded in the genome of human.


MYT1_HUMAN Myelin transcription factor 1 (sprot)

A myelin transcription factor 1 that is encoded in the genome of human.


MRP6_HUMAN ATP-binding cassette sub-family C member 6 (sprot)

An ATP-binding cassette sub-family C member 6 that is encoded in the genome of human.


Deanol

An antidepressive agent that has also been used in the treatment of movement disorders. The mechanism of action is not well understood.

A  tertiary amine that is ethanolamine having two N-methyl substituents.


SC5A7_MOUSE High affinity choline transporter 1 (sprot)

A high affinity choline transporter 1 that is encoded in the genome of mouse.


SC6A8_RAT Sodium- and chloride-dependent creatine transporter 1 (sprot)

A sodium- and chloride-dependent creatine transporter 1 that is encoded in the genome of rat.


Debrisoquine

An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.


Decamethonium

A quaternary ammonium ion that is a depolarising muscle relaxant whose structure comprises a decane-1,10-diamine core in which each amino group carries three methyl substituents.


ACHG_HUMAN Acetylcholine receptor subunit gamma (sprot)

An acetylcholine receptor subunit gamma that is encoded in the genome of human.


ACHE_HUMAN Acetylcholine receptor subunit epsilon (sprot)

An acetylcholine receptor subunit epsilon that is encoded in the genome of human.


HIF1A_HUMAN Hypoxia-inducible factor 1-alpha (sprot)

A hypoxia-inducible factor 1-alpha that is encoded in the genome of human.


Q9GRG7_9TRYP Glucose-6-phosphate 1-dehydrogenase (trembl)


BGLR_HUMAN Beta-glucuronidase (sprot)

A beta-glucuronidase that is encoded in the genome of human.


Demecarium

major descriptor (65-85); on-line search AMMONIUM COMPOUNDS (66-85); Index Medicus search DEMECARIUM BROMIDE (65-85)

The bis(quaternary ammonium) dication obtained by N,N'-dimethylation of the N,N'-bis[3-(dimethylamino)phenyl carbamate] derivative of 2,13-diazatetradecane.


RS4_ECOLI Small ribosomal subunit protein uS4 (sprot)

A 30S ribosomal protein S4 that is encoded in the genome of Escherichia coli K-12.


RS9_ECOLI Small ribosomal subunit protein uS9 (sprot)

A 30S ribosomal protein S9 that is encoded in the genome of Escherichia coli K-12.


SGMR1_CAVPO Sigma non-opioid intracellular receptor 1 (sprot)

A sigma non-opioid intracellular receptor 1 that is encoded in the genome of guinea pig.


SCN1A_RAT Sodium channel protein type 1 subunit alpha (sprot)

A sodium channel protein type 1 subunit alpha that is encoded in the genome of rat.


SCN2A_RAT Sodium channel protein type 2 subunit alpha (sprot)

A sodium channel protein type 2 subunit alpha that is encoded in the genome of rat.


SCN3A_RAT Sodium channel protein type 3 subunit alpha (sprot)

A sodium channel protein type 3 subunit alpha that is encoded in the genome of rat.


T2R46_HUMAN Taste receptor type 2 member 46 (sprot)

A taste receptor type 2 member 46 that is encoded in the genome of human.


THB_RAT Thyroid hormone receptor beta (sprot)

A thyroid hormone receptor beta that is encoded in the genome of rat.


CASP3_HUMAN Caspase-3 (sprot)

A caspase-3 that is encoded in the genome of human.


CASP7_HUMAN Caspase-7 (sprot)

A caspase-7 that is encoded in the genome of human.


GLD1_CAEEL Female germline-specific tumor suppressor gld-1 (sprot)

A protein that is a translation product of the gld-1 gene in worm.


NAAA_HUMAN N-acylethanolamine-hydrolyzing acid amidase (sprot)

An N-acylethanolamine-hydrolyzing acid amidase that is encoded in the genome of human.


AK1C2_HUMAN Aldo-keto reductase family 1 member C2 (sprot)

An aldo-keto reductase family 1 member C2 that is encoded in the genome of human.


NAMPT_HUMAN Nicotinamide phosphoribosyltransferase (sprot)

A nicotinamide phosphoribosyltransferase that is encoded in the genome of human.


KCJ11_MOUSE ATP-sensitive inward rectifier potassium channel 11 (sprot)

An ATP-sensitive inward rectifier potassium channel 11 that is encoded in the genome of mouse.


Dibekacin

Analog of KANAMYCIN with antitubercular as well as broad-spectrum antimicrobial properties.

A kanamycin that is kanamycin B lacking the 3- and 4-hydroxy groups on the 2,6-diaminosugar ring.


PDK1_HUMAN [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (sprot)

A [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial that is encoded in the genome of human.


PDK2_HUMAN [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (sprot)

A [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial that is encoded in the genome of human.


PDK3_HUMAN [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (sprot)

A [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial that is encoded in the genome of human.


PDK4_HUMAN [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (sprot)

A [pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial that is encoded in the genome of human.


BIP_HUMAN Endoplasmic reticulum chaperone BiP (sprot)

An endoplasmic reticulum chaperone BiP that is encoded in the genome of human.


NR1I2_MOUSE Nuclear receptor subfamily 1 group I member 2 (sprot)

A nuclear receptor subfamily 1 group I member 2 that is encoded in the genome of mouse.


Dexamethasone palmitate

a liposteroid for treatment of hemophagocytic lymphohistiocytosis


ACM4_MOUSE Muscarinic acetylcholine receptor M4 (sprot)

A muscarinic acetylcholine receptor M4 that is encoded in the genome of mouse.


ACM5_MOUSE Muscarinic acetylcholine receptor M5 (sprot)

A muscarinic acetylcholine receptor M5 that is encoded in the genome of mouse.


ACM3_MOUSE Muscarinic acetylcholine receptor M3 (sprot)

A muscarinic acetylcholine receptor M3 that is encoded in the genome of mouse.


Dexloxiglumide

a CCK receptor antagonist; structure given in first source


CAC1D_RAT Voltage-dependent L-type calcium channel subunit alpha-1D (sprot)

A voltage-dependent L-type calcium channel subunit alpha-1D that is encoded in the genome of rat.


TAAR1_MACMU Trace amine-associated receptor 1 (sprot)

A trace amine-associated receptor 1 that is encoded in the genome of Macaca mulatta.


TAAR1_RAT Trace amine-associated receptor 1 (sprot)

A protein that is a translation product of the Taar1 gene in rat.


TAAR1_MOUSE Trace amine-associated receptor 1 (sprot)

A trace amine-associated receptor 1 that is encoded in the genome of mouse.


IL8_HUMAN Interleukin-8 (sprot)

An interleukin-8 that is encoded in the genome of human.


AK1BA_HUMAN Aldo-keto reductase family 1 member B10 (sprot)

An aldo-keto reductase family 1 member B10 that is encoded in the genome of human.


UD17_HUMAN UDP-glucuronosyltransferase 1A7 (sprot)

A protein that is a translation product of the UGT1A7 gene in human.


UD16_HUMAN UDP-glucuronosyltransferase 1-6 (sprot)

A UDP-glucuronosyltransferase 1-6 that is encoded in the genome of human.


UD19_HUMAN UDP-glucuronosyltransferase 1A9 (sprot)

A UDP-glucuronosyltransferase 1A9 that is encoded in the genome of human.


UD110_HUMAN UDP-glucuronosyltransferase 1A10 (sprot)

A UDP-glucuronosyltransferase 1A10 that is encoded in the genome of human.


TRPM3_HUMAN Transient receptor potential cation channel subfamily M member 3 (sprot)

A transient receptor potential cation channel subfamily M member 3 that is encoded in the genome of human.


PCSK7_HUMAN Proprotein convertase subtilisin/kexin type 7 (sprot)

A proprotein convertase subtilisin/kexin type 7 that is encoded in the genome of human.


HIS1_MYCTU ATP phosphoribosyltransferase (sprot)


NQO1_RAT NAD(P)H dehydrogenase [quinone] 1 (sprot)

An NAD(P)H dehydrogenase [quinone] 1 that is encoded in the genome of rat.


Q72549_9HIV1 Reverse transcriptase/RNaseH (Fragment) (trembl)


Diethazine

phenothiazine derivative anti-Parkinson agent with anticholinergic and antihistaminic actions; is effective against Parkinson tremor; minor descriptor (75-86); on-line & INDEX MEDICUS search PHENOTHIAZINES (75-86); RN given refers to cpd without isomeric designation


ERR3_HUMAN Estrogen-related receptor gamma (sprot)

An estrogen-related receptor gamma that is encoded in the genome of human.


ERR2_HUMAN Steroid hormone receptor ERR2 (sprot)

A steroid hormone receptor ERR2 that is encoded in the genome of human.


GALE_HUMAN UDP-glucose 4-epimerase (sprot)

A UDP-glucose 4-epimerase that is encoded in the genome of human.


ERR1_MOUSE Steroid hormone receptor ERR1 (sprot)

A steroid hormone receptor ERR1 that is encoded in the genome of mouse.


ACMSD_HUMAN 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (sprot)

A 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase that is encoded in the genome of human.


AT1A1_CANLF Sodium/potassium-transporting ATPase subunit alpha-1 (sprot)

A sodium/potassium-transporting ATPase subunit alpha-1 that is encoded in the genome of dog.


STAT3_HUMAN Signal transducer and activator of transcription 3 (sprot)

A signal transducer and activator of transcription 3 that is encoded in the genome of human.


RORG_HUMAN Nuclear receptor ROR-gamma (sprot)

A nuclear receptor ROR-gamma that is encoded in the genome of human.


RORG_MOUSE Nuclear receptor ROR-gamma (sprot)

A nuclear receptor ROR-gamma that is encoded in the genome of mouse.


alpha-Ergocryptine

a component of the ergotoxine complex; it is the main ergot alkaloid of Japanese & South American wid grasses; minor descriptor (76-86); on-line & INDEX MEDICUS search ERGOLINES (76-86); RN given refers to ((5'alpha)-isomer)

Ergotaman bearing hydroxy, isopropyl, and 2-methylpropyl groups at the 12', 2' and 5' positions, respectively, and oxo groups at positions 3', 6', and 18. It is a natural ergot alkaloid. Ergocryptine discussed in the literature prior to 1967, when beta-ergocryptine was separated from alpha-ergocryptine, is now referred to as alpha-ergocryptine.


Dihydroergocristine

A 9,10alpha-dihydro derivative of ERGOTAMINE that contains an isopropyl sidechain at the 2' position of the molecule.

Ergocristine in which a single bond replaces the double bond between positions 9 and 10. It is used as the mesylate salt for the symptomatic treatment of mental deterioration associated with cerebrovascular insufficiency and in peripheral vascular disease.


GASR_MOUSE Gastrin/cholecystokinin type B receptor (sprot)

A cholecystokinin receptor 2 that is encoded in the genome of mouse.


Dihydroquinidine

urinary quinine metabolite; RN given refers to (9S)-isomer; structure in Merck Index, 9th ed, #4703


SCN1B_HUMAN Sodium channel subunit beta-1 (sprot)

A sodium channel subunit beta-1 that is encoded in the genome of human.


SCN2B_HUMAN Sodium channel subunit beta-2 (sprot)

A sodium channel subunit beta-2 that is encoded in the genome of human.


SCN3B_HUMAN Sodium channel subunit beta-3 (sprot)

A sodium channel subunit beta-3 that is encoded in the genome of human.


SCN4B_HUMAN Sodium channel subunit beta-4 (sprot)

A sodium channel subunit beta-4 that is encoded in the genome of human.


Dilazep

Coronary vasodilator with some antiarrhythmic activity.

A member of the class of diazepanes that is 1,4-diazepane substituted by 3-[(3,4,5-trimethoxybenzoyl)oxy]propyl groups at positions 1 and 4. It is a potent adenosine uptake inhibitor that exhibits antiplatelet, antianginal and vasodilator properties.


S29A1_HUMAN Equilibrative nucleoside transporter 1 (sprot)

An equilibrative nucleoside transporter 1 that is encoded in the genome of human.


S29A2_RAT Equilibrative nucleoside transporter 2 (sprot)

An equilibrative nucleoside transporter 2 that is encoded in the genome of rat.


Dilevalol

A 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide that has 1R,2R-configuration.


CAC1S_HUMAN Voltage-dependent L-type calcium channel subunit alpha-1S (sprot)

A voltage-dependent L-type calcium channel subunit alpha-1S that is encoded in the genome of human.


KCNC1_MOUSE Potassium voltage-gated channel subfamily C member 1 (sprot)

A voltage-gated potassium channel KCNC1 that is encoded in the genome of mouse.


KCNA7_MOUSE Potassium voltage-gated channel subfamily A member 7 (sprot)

A voltage-gated potassium channel subunit KCNA7 that is encoded in the genome of mouse.


CAC1F_MOUSE Voltage-dependent L-type calcium channel subunit alpha-1F (sprot)

A voltage-dependent L-type calcium channel subunit alpha-1F that is encoded in the genome of mouse.


Dimetacrine

minor descriptor (75-84); on-line & Index Medicus search ACRIDINES (75-84); RN given refers to parent cpd without isomeric designation


Q7KQK5_PLAF7 Apical membrane antigen 1 (trembl)


A4TVL0_9PROT Cereblon isoform 4 (trembl)


MAP2_HUMAN Methionine aminopeptidase 2 (sprot)

A methionine aminopeptidase 2 that is encoded in the genome of human.


MAP11_HUMAN Methionine aminopeptidase 1 (sprot)

A methionine aminopeptidase 1 that is encoded in the genome of human.


PD2R2_HUMAN Prostaglandin D2 receptor 2 (sprot)

A prostaglandin D2 receptor DP2 that is encoded in the genome of human.


TA2R_HUMAN Thromboxane A2 receptor (sprot)

A thromboxane A2 receptor that is encoded in the genome of human.


PF2R_BOVIN Prostaglandin F2-alpha receptor (sprot)

A prostaglandin F2-alpha receptor that is encoded in the genome of cow.


PF2R_MOUSE Prostaglandin F2-alpha receptor (sprot)

A prostaglandin F2-alpha receptor that is encoded in the genome of mouse.


PD2R2_MOUSE Prostaglandin D2 receptor 2 (sprot)

A prostaglandin D2 receptor DP2 that is encoded in the genome of mouse.


S22AK_MOUSE Solute carrier family 22 member 20 (sprot)

A protein that is a translation product of the Slc22a20 gene in mouse.


PDE11_HUMAN Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (sprot)

A dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A that is encoded in the genome of human.


PDE10_HUMAN cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (sprot)

A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A that is encoded in the genome of human.


PDE8B_HUMAN High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (sprot)

A high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B that is encoded in the genome of human.


PDE7B_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 7B (sprot)

A cAMP-specific 3',5'-cyclic phosphodiesterase 7B that is encoded in the genome of human.


PDE8A_HUMAN High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (sprot)

A high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A that is encoded in the genome of human.


O77823_PIG 3',5'-cyclic-AMP phosphodiesterase (Fragment) (trembl)


PDE7A_HUMAN High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (sprot)

A high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A that is encoded in the genome of human.


PDE6D_HUMAN Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (sprot)

A retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta that is encoded in the genome of human.


CNRG_HUMAN Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (sprot)

A retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma that is encoded in the genome of human.


CNCG_HUMAN Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (sprot)

A retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma that is encoded in the genome of human.


PDE6A_HUMAN Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (sprot)

A rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha that is encoded in the genome of human.


PDE6B_HUMAN Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (sprot)

A rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta that is encoded in the genome of human.


PDE6C_HUMAN Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (sprot)

A cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' that is encoded in the genome of human.


PDE1A_HUMAN Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (sprot)

A dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A that is encoded in the genome of human.


PDE1B_HUMAN Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B (sprot)

A dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B that is encoded in the genome of human.


PDE1C_HUMAN Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (sprot)

A dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C that is encoded in the genome of human.


PRUN1_HUMAN Exopolyphosphatase PRUNE1 (sprot)

An exopolyphosphatase PRUNE1 that is encoded in the genome of human.


R1AB_SARS2 Replicase polyprotein 1ab (sprot)


ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial (sprot)

An aldehyde dehydrogenase, mitochondrial that is encoded in the genome of human.


CCR5_HUMAN C-C chemokine receptor type 5 (sprot)

A C-C chemokine receptor type 5 that is encoded in the genome of human.


CXCR2_HUMAN C-X-C chemokine receptor type 2 (sprot)

A C-X-C chemokine receptor type 2 that is encoded in the genome of human.


ALDH2_RAT Aldehyde dehydrogenase, mitochondrial (sprot)

An aldehyde dehydrogenase, mitochondrial that is encoded in the genome of rat.


MGLL_HUMAN Monoglyceride lipase (sprot)

A monoglyceride lipase that is encoded in the genome of human.


GLMU_MYCTU Bifunctional protein GlmU (sprot)

A bifunctional protein GlmU that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


LYOX_HUMAN Protein-lysine 6-oxidase (sprot)

A protein-lysine 6-oxidase that is encoded in the genome of human.


LOXL3_HUMAN Lysyl oxidase homolog 3 (sprot)

A lysyl oxidase homolog 3 that is encoded in the genome of human.


LOXL4_HUMAN Lysyl oxidase homolog 4 (sprot)

A lysyl oxidase homolog 4 that is encoded in the genome of human.


EHMT2_HUMAN Histone-lysine N-methyltransferase EHMT2 (sprot)

A histone-lysine N-methyltransferase, H3 lysine-9 specific 3 that is encoded in the genome of human.


EHMT1_HUMAN Histone-lysine N-methyltransferase EHMT1 (sprot)

A histone-lysine N-methyltransferase, H3 lysine-9 specific 5 that is encoded in the genome of human.


LOXL2_HUMAN Lysyl oxidase homolog 2 (sprot)

A lysyl oxidase homolog 2 that is encoded in the genome of human.


GSDMD_HUMAN Gasdermin-D (sprot)

A gasdermin-D that is encoded in the genome of human.


GSDMD_MOUSE Gasdermin-D (sprot)

A gasdermin-D that is encoded in the genome of mouse.


Diethyldithiocarbamic acid

A chelating agent that has been used to mobilize toxic metals from the tissues of humans and experimental animals. It is the main metabolite of DISULFIRAM.

A member of the class of dithiocarbamic acids that is diethylcarbamic acid in which both of the oxygens are replaced by sulfur.


CP2E1_HUMAN Cytochrome P450 2E1 (sprot)

A cytochrome P450 2E1 that is encoded in the genome of human.


TRPM8_MOUSE Transient receptor potential cation channel subfamily M member 8 (sprot)

A transient receptor potential cation channel TRPM8 that is encoded in the genome of mouse.


TRPM8_RAT Transient receptor potential cation channel subfamily M member 8 (sprot)

A transient receptor potential cation channel TRPM8 that is encoded in the genome of rat.


TRPM8_HUMAN Transient receptor potential cation channel subfamily M member 8 (sprot)

A transient receptor potential cation channel TRPM8 that is encoded in the genome of human.


GHRHR_HUMAN Growth hormone-releasing hormone receptor (sprot)

A growth hormone-releasing hormone receptor that is encoded in the genome of human.


TBB4A_HUMAN Tubulin beta-4A chain (sprot)

A tubulin beta-4A chain that is encoded in the genome of human.


TBB3_HUMAN Tubulin beta-3 chain (sprot)

A tubulin beta-3 chain that is encoded in the genome of human.


TBB2A_HUMAN Tubulin beta-2A chain (sprot)

A tubulin beta-2A chain that is encoded in the genome of human.


TBB8_HUMAN Tubulin beta-8 chain (sprot)

A tubulin beta-8 chain that is encoded in the genome of human.


TBB6_HUMAN Tubulin beta-6 chain (sprot)

A tubulin beta-6 chain that is encoded in the genome of human.


TBB2B_HUMAN Tubulin beta-2B chain (sprot)

A tubulin beta-2B chain that is encoded in the genome of human.


TBB1_HUMAN Tubulin beta-1 chain (sprot)

A tubulin beta-1 chain that is encoded in the genome of human.


GN_HHV11 Envelope glycoprotein N (sprot)

A protein that is a translation product of the gN gene in Herpes simplex virus type 1 strain 17.


GM_HHV11 Envelope glycoprotein M (sprot)

A protein that is a translation product of the gM gene in Herpes simplex virus type 1 strain 17.


GE_HHV11 Envelope glycoprotein E (sprot)

A protein that is a translation product of the gE gene in Herpes simplex virus type 1 strain 17.


GH_HHV11 Envelope glycoprotein H (sprot)

A protein that is a translation product of the gH gene in Herpes simplex virus type 1 strain 17.


GJ_HHV11 Envelope glycoprotein J (sprot)

A protein that is a translation product of the gJ gene in Herpes simplex virus type 1 strain 17.


GG_HHV11 Envelope glycoprotein G (sprot)

A protein that is a translation product of the gG gene in Herpes simplex virus type 1 strain 17.


GI_HHV11 Envelope glycoprotein I (sprot)

A protein that is a translation product of the gI gene in Herpes simplex virus type 1 strain 17.


GL_HHV11 Envelope glycoprotein L (sprot)

A protein that is a translation product of the gL gene in Herpes simplex virus type 1 strain 17.


GB_HHV11 Envelope glycoprotein B (sprot)

A protein that is a translation product of the gB gene in Herpes simplex virus type 1 strain 17.


GC_HHV11 Envelope glycoprotein C (sprot)


GK_HHV11 Envelope glycoprotein K (sprot)

A protein that is a translation product of the gK gene in Herpes simplex virus type 1 strain 17.


GD_HHV11 Envelope glycoprotein D (sprot)

A protein that is a translation product of the gD gene in Herpes simplex virus type 1 strain 17.


CLAT_RAT Choline O-acetyltransferase (sprot)

A choline O-acetyltransferase that is encoded in the genome of rat.


ACES_TETCF Acetylcholinesterase (sprot)

An acetylcholinesterase that is encoded in the genome of Tetronarce californica.


Q9JKC1_RAT Carboxylic ester hydrolase (trembl)


ACES_RAT Acetylcholinesterase (sprot)

An acetylcholinesterase that is encoded in the genome of rat.


CHLE_MOUSE Cholinesterase (sprot)

A cholinesterase that is encoded in the genome of mouse.


Q9N1N9_HORSE Carboxylic ester hydrolase (trembl)


ADRB2_CANLF Beta-2 adrenergic receptor (sprot)

A beta-2 adrenergic receptor that is encoded in the genome of dog.


DOPO_HUMAN Dopamine beta-hydroxylase (sprot)

A dopamine beta-hydroxylase that is encoded in the genome of human.


MMP8_HUMAN Neutrophil collagenase (sprot)

A neutrophil collagenase that is encoded in the genome of human.


DNPEP_PLAF7 Aspartyl aminopeptidase (sprot)


CASP1_HUMAN Caspase-1 (sprot)

A caspase-1 that is encoded in the genome of human.


TERT_HUMAN Telomerase reverse transcriptase (sprot)

A telomerase reverse transcriptase that is encoded in the genome of human.


RNAS1_BOVIN Ribonuclease pancreatic (sprot)

A protein that is a translation product of the RNASE1 gene in cow.


T2D3_HAEIN Type II restriction enzyme HindIII (sprot)

A DNA restriction-modification endonuclease that is a translation product of the hindIIIR gene in Haemophilus influenzae Rd KW20.


T2S1_STRCS Type II restriction enzyme ScaI (sprot)

A DNA restriction-modification endonuclease that is a translation product of the scaIR gene in Streptomyces caespitosus.


GLF_MYCTU UDP-galactopyranose mutase (sprot)

A UDP-galactopyranose mutase that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


DNM3A_MOUSE DNA (cytosine-5)-methyltransferase 3A (sprot)

A DNA (cytosine-5)-methyltransferase 3A that is encoded in the genome of mouse.


TCR2_ECOLX Tetracycline resistance protein, class B (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the tetA gene in Escherichia coli.


MMP7_HUMAN Matrilysin (sprot)

A matrilysin that is encoded in the genome of human.


Drotaverine

Hungarian drug; RN given refers to parent cpd; structure


GSTA1_HUMAN Glutathione S-transferase A1 (sprot)

A glutathione S-transferase A1 that is encoded in the genome of human.


GLYM_HUMAN Serine hydroxymethyltransferase, mitochondrial (sprot)

A serine hydroxymethyltransferase, mitochondrial that is encoded in the genome of human.


S5A1_HUMAN 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (sprot)

A 3-oxo-5-alpha-steroid 4-dehydrogenase 1 that is encoded in the genome of human.


NR2E1_HUMAN Nuclear receptor subfamily 2 group E member 1 (sprot)

A nuclear receptor subfamily 2 group E member 1 that is encoded in the genome of human.


Ebrotidine

an H2-receptor antagonist and gastric mucosa protector


NPY2R_HUMAN Neuropeptide Y receptor type 2 (sprot)

A neuropeptide Y receptor type 2 that is encoded in the genome of human.


CRCM1_HUMAN Calcium release-activated calcium channel protein 1 (sprot)

A calcium release-activated calcium channel protein 1 that is encoded in the genome of human.


FOLC_HUMAN Folylpolyglutamate synthase, mitochondrial (sprot)

A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of human.


CEGT_HUMAN Ceramide glucosyltransferase (sprot)

A ceramide glucosyltransferase that is encoded in the genome of human.


Q9XAY4_PSEAI Beta-lactamase VIM-1 (trembl)


Q9WJQ2_9HIV1 Reverse transcriptase protein (Fragment) (trembl)


CP46A_HUMAN Cholesterol 24-hydroxylase (sprot)

A cytochrome P450 46A1 that is encoded in the genome of human.


DCOR_HUMAN Ornithine decarboxylase (sprot)

An ornithine decarboxylase that is encoded in the genome of human.


DCOR_RAT Ornithine decarboxylase (sprot)

An ornithine decarboxylase that is encoded in the genome of rat.


Q9TZZ6_TRYBG Ornithine decarboxylase (trembl)


CAC1G_RAT Voltage-dependent T-type calcium channel subunit alpha-1G (sprot)

A voltage-dependent T-type calcium channel subunit alpha-1G that is encoded in the genome of rat.


Elliptinium

synthetic ellipticine deriv; RN given refers to parent cpd; structure given in first source


Pregnanolone

A pregnane found in the urine of pregnant women and sows. It has anesthetic, hypnotic, and sedative properties.

The 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one.


Emetine

The principal alkaloid of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae. It is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS.

A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties.


RBBP9_HUMAN Serine hydrolase RBBP9 (sprot)

A serine hydrolase RBBP9 that is encoded in the genome of human.


A0A143MHK7_ZIKV Genome polyprotein (Fragment) (trembl)


ACE2_RAT Angiotensin-converting enzyme 2 (sprot)

An angiotensin-converting enzyme 2 that is encoded in the genome of rat.


ACE_MOUSE Angiotensin-converting enzyme (sprot)

An angiotensin-converting enzyme that is encoded in the genome of mouse.


Q53I07_9HIV1 Env polyprotein (Fragment) (trembl)


O40239_9PLVG Env polyprotein (Fragment) (trembl)


Q76270_9HIV1 Env polyprotein (Fragment) (trembl)


VATB2_HUMAN V-type proton ATPase subunit B, brain isoform (sprot)

A V-type proton ATPase subunit B, brain isoform that is encoded in the genome of human.


PARC_NEIGO DNA topoisomerase 4 subunit A (sprot)


GYRB_NEIGO Antibiotic resistant DNA gyrase subunit B (sprot)


TRBP2_HUMAN RISC-loading complex subunit TARBP2 (sprot)

A RISC-loading complex subunit TARBP2 that is encoded in the genome of human.


Enoximone

A selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with CONGESTIVE HEART FAILURE.


Enprofylline

Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.


Gardrin

A synthetic PGE2 analog that has an inhibitory effect on gastric acid secretion, a mucoprotective effect, and a postprandial lowering effect on gastrin. It has been shown to be efficient and safe in the treatment of gastroduodenal ulcers.


FTO_HUMAN Alpha-ketoglutarate-dependent dioxygenase FTO (sprot)

An alpha-ketoglutarate-dependent dioxygenase FTO that is encoded in the genome of human.


AK1A1_HUMAN Aldo-keto reductase family 1 member A1 (sprot)

An aldo-keto reductase family 1 member A1 that is encoded in the genome of human.


AK1A1_PIG Aldo-keto reductase family 1 member A1 (sprot)

An aldo-keto reductase family 1 member A1 that is encoded in the genome of pig.


AK1A1_RAT Aldo-keto reductase family 1 member A1 (sprot)

An aldo-keto reductase family 1 member A1 that is encoded in the genome of rat.


DHSO_HUMAN Sorbitol dehydrogenase (sprot)

A sorbitol dehydrogenase that is encoded in the genome of human.


CP4AB_HUMAN Cytochrome P450 4A11 (sprot)

A cytochrome P450 4A11 that is encoded in the genome of human.


ADRB2_RAT Beta-2 adrenergic receptor (sprot)

A beta-2 adrenergic receptor that is encoded in the genome of rat.


A3EZI9_9HEPC Genome polyprotein (Fragment) (trembl)


A3EZJ3_9HEPC Genome polyprotein (Fragment) (trembl)


AGTRB_RAT Type-1 angiotensin II receptor B (sprot)

An angiotensin II receptor 1B that is encoded in the genome of rat.


AGTR2_RAT Type-2 angiotensin II receptor (sprot)

An angiotensin II receptor 2 that is encoded in the genome of rat.


AGTRA_RAT Type-1 angiotensin II receptor A (sprot)

An angiotensin II receptor 1A that is encoded in the genome of rat.


ITB3_HUMAN Integrin beta-3 (sprot)

An integrin beta-3 that is encoded in the genome of human.


ITA2B_HUMAN Integrin alpha-IIb (sprot)

An integrin alpha-IIb that is encoded in the genome of human.


MK09_HUMAN Mitogen-activated protein kinase 9 (sprot)

A mitogen-activated protein kinase 9 that is encoded in the genome of human.


CCKAR_MOUSE Cholecystokinin receptor type A (sprot)

A cholecystokinin receptor 1 that is encoded in the genome of mouse.