SEP15_HUMAN Selenoprotein F (sprot)

A selenoprotein F that is encoded in the genome of human.


SELN_HUMAN Selenoprotein N (sprot)

A selenoprotein N that is encoded in the genome of human.


SELW_HUMAN Selenoprotein W (sprot)

A selenoprotein W that is encoded in the genome of human.


SELS_HUMAN Selenoprotein S (sprot)

A selenoprotein S that is encoded in the genome of human.


SELK_HUMAN Selenoprotein K (sprot)

A selenoprotein K that is encoded in the genome of human.


SELM_HUMAN Selenoprotein M (sprot)

A selenoprotein M that is encoded in the genome of human.


Deoxyribose 1-phosphate

A 2-deoxyribose 1-phosphate with D-ribofuranose as the sugar. An intermediate in the metabolism of pyrimidine.


HYI_HUMAN Putative hydroxypyruvate isomerase (sprot)

A putative hydroxypyruvate isomerase that is encoded in the genome of human.


3-Hydroxypyruvic acid

A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a hydroxy group. It is an intermediate involved in the glycine and serine metabolism.


An (S)-3-hydroxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (2S,3S)-3-hydroxy-2-methylbutanoic acid.


RGR_HUMAN RPE-retinal G protein-coupled receptor (sprot)

An RPE-retinal G protein-coupled receptor that is encoded in the genome of human.


Retinal

A retinal in which all four exocyclic double bonds have E- (trans-) geometry.


Carbon Monoxide

A one-carbon compound in which the carbon is joined only to a single oxygen. It is a colourless, odourless, tasteless, toxic gas.


Omeprazole Metabolism Pathway,Drug Metabolism

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent


Pantoprazole Metabolism Pathway,Drug Metabolism


Rabeprazole Metabolism Pathway,Drug Metabolism


HVCN1_HUMAN Voltage-gated hydrogen channel 1 (sprot)

A voltage-gated hydrogen channel 1 that is encoded in the genome of human.


HYDROGEN

An elemental molecule consisting of two hydrogens joined by a single bond.


Adenosine tetraphosphate

A purine ribonucleoside 5'-tetraphosphate having adenine as the nucleobase.


A N-acetyl-D-glucosamine 1-phosphate that is 2-deoxy-D-glucopyranose 1-(dihydrogen phosphate) substituted by an acetamido group at position 2.


3-Mercaptopyruvic acid

A 2-oxo monocarboxylic acid that is  pyruvic acid substituted by a sulfanyl group at position 3.


Thiamine diphosphate

A thiamine phosphate that is thiamine(1+) in which the hydroxy group has been replaced by a diphosphate group. It is the active form of vitamin B1 and an essential cofactor for enzymes in key metabolic pathways.


dephospho-CoA

An adenosine 5'-phosphate that is coenzyme A in which the phosphate group at position 3' has been replaced by a hydrogen atom. It is an intermediate metabolite in pantothenate and CoA biosynthesis.


HMG-CoA

A 3-hydroxy-3-methylglutaryl-CoA where the 3-hydroxy-3-methylglutaryl component has (S)-configuration.


CP4FC_HUMAN Cytochrome P450 4F12 (sprot)

A cytochrome P450 4F12 that is encoded in the genome of human.


HBB_HUMAN Hemoglobin subunit beta (sprot)

A hemoglobin subunit beta that is encoded in the genome of human.


MYG_HUMAN Myoglobin (sprot)

A myoglobin that is encoded in the genome of human.


HBG2_HUMAN Hemoglobin subunit gamma-2 (sprot)

A hemoglobin subunit gamma-2 that is encoded in the genome of human.


CX7A2_HUMAN Cytochrome c oxidase subunit 7A2, mitochondrial (sprot)

A cytochrome c oxidase subunit 7A2, mitochondrial that is encoded in the genome of human.


CX7B2_HUMAN Cytochrome c oxidase subunit 7B2, mitochondrial (sprot)

A cytochrome c oxidase subunit 7B2, mitochondrial that is encoded in the genome of human.


CX6B2_HUMAN Cytochrome c oxidase subunit 6B2 (sprot)

A cytochrome c oxidase subunit 6B2 that is encoded in the genome of human.


COX7R_HUMAN Cytochrome c oxidase subunit 7A-related protein, mitochondrial (sprot)

A cytochrome c oxidase subunit 7A-related protein, mitochondrial that is encoded in the genome of human.


COX8C_HUMAN Cytochrome c oxidase subunit 8C, mitochondrial (sprot)

A cytochrome c oxidase subunit 8C, mitochondrial that is encoded in the genome of human.


CX6A1_HUMAN Cytochrome c oxidase subunit 6A1, mitochondrial (sprot)

A cytochrome c oxidase subunit 6A1, mitochondrial that is encoded in the genome of human.


COX42_HUMAN Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (sprot)

A cytochrome c oxidase subunit 4 isoform 2, mitochondrial that is encoded in the genome of human.


CP20A_HUMAN Cytochrome P450 20A1 (sprot)

A cytochrome P450 20A1 that is encoded in the genome of human.


CP2U1_HUMAN Cytochrome P450 2U1 (sprot)

A cytochrome P450 2U1 that is encoded in the genome of human.


CYGB_HUMAN Cytoglobin (sprot)

A cytoglobin that is encoded in the genome of human.


HBD_HUMAN Hemoglobin subunit delta (sprot)

A hemoglobin subunit delta that is encoded in the genome of human.


NGB_HUMAN Neuroglobin (sprot)

A neuroglobin that is encoded in the genome of human.


DOHH_HUMAN Deoxyhypusine hydroxylase (sprot)

A deoxyhypusine hydroxylase that is encoded in the genome of human.


PIR_HUMAN Pirin (sprot)

A pirin that is encoded in the genome of human.


PTGDS_HUMAN Prostaglandin-H2 D-isomerase (sprot)

A prostaglandin-H2 D-isomerase that is encoded in the genome of human.


THAS_HUMAN Thromboxane-A synthase (sprot)

A thromboxane-A synthase that is encoded in the genome of human.


Q53F23_HUMAN HCG14925, isoform CRA_a (Fragment) (trembl)


Sphinganine 1-phosphate

A sphingoid 1-phosphate that is the monophosphorylated derivative of  sphinganine.


N-methylphenylethanolamine

An  alkaloid that is ethanolamine having the phenyl group at the 1-position and a methyl group attached to the nitrogen. It has been isolated from Halostachys caspica.


FADS1_HUMAN Acyl-CoA (8-3)-desaturase (sprot)

An acyl-CoA (8-3)-desaturase that is encoded in the genome of human.


FADS2_HUMAN Acyl-CoA 6-desaturase (sprot)

An acyl-CoA 6-desaturase that is encoded in the genome of human.


Linolenic Acid

A linolenic acid with cis-double bonds at positions 9, 12 and 15. Shown to have an antithrombotic effect.


MTR1A_HUMAN Melatonin receptor type 1A (sprot)

A melatonin receptor type 1A that is encoded in the genome of human.


MTR1B_HUMAN Melatonin receptor type 1B (sprot)

A melatonin receptor type 1B that is encoded in the genome of human.


RORB_HUMAN Nuclear receptor ROR-beta (sprot)

A nuclear receptor ROR-beta that is encoded in the genome of human.


Melatonin

A member of the class of  acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans.


4-Aminobenzoic acid

An aminobenzoic acid in which the amino group is para to the carboxy group.


APOE_HUMAN Apolipoprotein E (sprot)

An apolipoprotein E that is encoded in the genome of human.


APOB_HUMAN Apolipoprotein B-100 (sprot)

An apolipoprotein B-100 that is encoded in the genome of human.


FGF2_HUMAN Fibroblast growth factor 2 (sprot)

A fibroblast growth factor 2 that is encoded in the genome of human.


PTN_HUMAN Pleiotrophin (sprot)

A pleiotrophin that is encoded in the genome of human.


FGF1_HUMAN Fibroblast growth factor 1 (sprot)

A fibroblast growth factor 1 that is encoded in the genome of human.


MK_HUMAN Midkine (sprot)

A midkine that is encoded in the genome of human.


HBEGF_HUMAN Proheparin-binding EGF-like growth factor (sprot)

A proheparin-binding EGF-like growth factor that is encoded in the genome of human.


FGF7_HUMAN Fibroblast growth factor 7 (sprot)

A fibroblast growth factor 7 that is encoded in the genome of human.


CAP7_HUMAN Azurocidin (sprot)

An azurocidin that is encoded in the genome of human.


FGF4_HUMAN Fibroblast growth factor 4 (sprot)

A fibroblast growth factor 4 that is encoded in the genome of human.


RL29_HUMAN Large ribosomal subunit protein eL29 (sprot)

A 60S ribosomal protein L29 that is encoded in the genome of human.


RL22_HUMAN Large ribosomal subunit protein eL22 (sprot)

A 60S ribosomal protein L22 that is encoded in the genome of human.


FGF5_HUMAN Fibroblast growth factor 5 (sprot)

A fibroblast growth factor 5 that is encoded in the genome of human.


FGF6_HUMAN Fibroblast growth factor 6 (sprot)

A fibroblast growth factor 6 that is encoded in the genome of human.


FGFP1_HUMAN Fibroblast growth factor-binding protein 1 (sprot)

A fibroblast growth factor-binding protein 1 that is encoded in the genome of human.


HDGF_HUMAN Hepatoma-derived growth factor (sprot)

A hepatoma-derived growth factor that is encoded in the genome of human.


FGF8_HUMAN Fibroblast growth factor 8 (sprot)

A fibroblast growth factor 8 that is encoded in the genome of human.


FGF3_HUMAN Fibroblast growth factor 3 (sprot)

A fibroblast growth factor 3 that is encoded in the genome of human.


neurodegenerative syndrome due to cerebral folate transport deficiency

biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:ThingWithTaxon

A reduced concentration of 5-methyltetrahydrofolate(2-) in the cerebrospinal fluid (CSF). 5-methyltetrahydrofolate is the active folate metabolite.


DLG4_HUMAN Disks large homolog 4 (sprot)

A disks large homolog 4 that is encoded in the genome of human.


A purine ribonucleoside 5'-monophosphate having guanine as the nucleobase.


Guaiacol

A  monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position.


A dTDP-sugar having 4-dehydro-6-deoxy-alpha-D-glucose as the sugar component.  It is an intermediate in dTDP-rhamnose biosynthesis.


G6PT1_HUMAN Glucose-6-phosphate exchanger SLC37A4 (sprot)

A glucose-6-phosphate exchanger SLC37A4 that is encoded in the genome of human.


Glucose 6-phosphate

A glucopyranose ring with a phosphate replacing the hydroxy in the hydroxymethyl group at position 6.


prostaglandin D2

A member of the class of  prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- stereoisomer).


3-Sulfinylpyruvic acid

A pyruvic acid compound having a 3-sulfinyl substituent.


Nicotinamide

A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.


2'-Deoxyuridine 5'-monophosphate

A pyrimidine 2'-deoxyribonucleoside 5'-monophosphate having uracil as the nucleobase.


cotinine N-oxide

An N-alkylpyrrolidine that is nicotine in which the methylene hydrogens at position 2 on the pyrrolidine ring have been replaced by an oxo group and the pyridine nitrogen converted into the corresponding N-oxide. A minor metabolite of nicotine.


Dihydropteroate

A pteroic acid derivative arising from formal hydrogenation of the 7,8-double bond of pteroic acid.


A four-carbon alkane-alpha,omega-diamine. It is obtained by the breakdown of amino acids and is responsible for the foul odour of putrefying flesh.


A4UCS3_HUMAN Acyl carrier protein (Fragment) (trembl)


Pantetheine 4'-phosphate with D (R) configuration at the 2' position.


A 24-hydroxycholesterol that has S configuration at position 24. It is the major metabolic breakdown product of cholesterol in the brain.


The 3-hydroxy derivative of N(6),N(6),N(6)-trimethyl-L-lysine


NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (sprot)

A glycylpeptide N-tetradecanoyltransferase 1 that is encoded in the genome of human.


NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (sprot)

A glycylpeptide N-tetradecanoyltransferase 2 that is encoded in the genome of human.


ABHD5_HUMAN 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (sprot)

A 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 that is encoded in the genome of human.


MBOA1_HUMAN Lysophospholipid acyltransferase 1 (sprot)

A lysophospholipid acyltransferase 1 that is encoded in the genome of human.


MBOA2_HUMAN Lysophospholipid acyltransferase 2 (sprot)

A lysophospholipid acyltransferase 2 that is encoded in the genome of human.


MBOA7_HUMAN Lysophospholipid acyltransferase 7 (sprot)

A lysophospholipid acyltransferase 7 that is encoded in the genome of human.


coenzyme A

A thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit.


Estrone sulfate

A steroid sulfate that is the 3-sulfate of estrone.


Formaldehyde

An aldehyde resulting from the formal oxidation of methanol.


perinatal lethal hypophosphatasia

A rare, genetic form of hypophosphatasia (HPP) characterized by markedly impaired bone mineralization in utero due to reduced activity of serum alkaline phosphatase (ALP) and causing stillbirth or respiratory failure within days of birth.


SYNJ2_HUMAN Synaptojanin-2 (sprot)

A synaptojanin-2 that is encoded in the genome of human.


INP5E_HUMAN Phosphatidylinositol polyphosphate 5-phosphatase type IV (sprot)

A phosphatidylinositol polyphosphate 5-phosphatase type IV that is encoded in the genome of human.


SYNJ1_HUMAN Synaptojanin-1 (sprot)

A synaptojanin-1 that is encoded in the genome of human.


DOPP1_HUMAN Dolichyldiphosphatase 1 (sprot)

A dolichyldiphosphatase 1 that is encoded in the genome of human.


APTX_HUMAN Aprataxin (sprot)

An aprataxin that is encoded in the genome of human.


PTN6_HUMAN Tyrosine-protein phosphatase non-receptor type 6 (sprot)

A tyrosine-protein phosphatase non-receptor type 6 that is encoded in the genome of human.


PTPRC_HUMAN Receptor-type tyrosine-protein phosphatase C (sprot)

A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of human.


PTPRA_HUMAN Receptor-type tyrosine-protein phosphatase alpha (sprot)

A receptor-type tyrosine-protein phosphatase alpha that is encoded in the genome of human.


MTM1_HUMAN Myotubularin (sprot)

A myotubularin that is encoded in the genome of human.


MTMR3_HUMAN Myotubularin-related protein 3 (sprot)

A myotubularin-related protein 3 that is encoded in the genome of human.


S25A3_HUMAN Solute carrier family 25 member 3 (sprot)

A phosphate carrier protein, mitochondrial that is encoded in the genome of human.


SHIP1_HUMAN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 (sprot)

A phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 that is encoded in the genome of human.


PP4P2_HUMAN Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (sprot)

A type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase that is encoded in the genome of human.


PP4P1_HUMAN Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (sprot)

A type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase that is encoded in the genome of human.


TPTE2_HUMAN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (sprot)

A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 that is encoded in the genome of human.


PTPM1_HUMAN Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (sprot)

A protein-tyrosine phosphatase mitochondrial 1 that is encoded in the genome of human.


AUXI_HUMAN Putative tyrosine-protein phosphatase auxilin (sprot)

A putative tyrosine-protein phosphatase auxilin that is encoded in the genome of human.


CNEP1_HUMAN CTD nuclear envelope phosphatase 1 (sprot)

A serine/threonine-protein phosphatase dullard that is encoded in the genome of human.


DUS28_HUMAN Dual specificity phosphatase 28 (sprot)

A dual specificity phosphatase 28 that is encoded in the genome of human.


DUS9_HUMAN Dual specificity protein phosphatase 9 (sprot)

A dual specificity protein phosphatase 9 that is encoded in the genome of human.


PLPR2_HUMAN Phospholipid phosphatase-related protein type 2 (sprot)

A phospholipid phosphatase-related protein type 2 that is encoded in the genome of human.


PLPR3_HUMAN Phospholipid phosphatase-related protein type 3 (sprot)

A phospholipid phosphatase-related protein type 3 that is encoded in the genome of human.


MPIP1_HUMAN M-phase inducer phosphatase 1 (sprot)

An M-phase inducer phosphatase 1 that is encoded in the genome of human.


MPIP2_HUMAN M-phase inducer phosphatase 2 (sprot)

An M-phase inducer phosphatase 2 that is encoded in the genome of human.


MPIP3_HUMAN M-phase inducer phosphatase 3 (sprot)

An M-phase inducer phosphatase 3 that is encoded in the genome of human.


MTMR4_HUMAN Myotubularin-related protein 4 (sprot)

A myotubularin-related protein 4 that is encoded in the genome of human.


MTMRE_HUMAN Myotubularin-related protein 14 (sprot)

A myotubularin-related protein 14 that is encoded in the genome of human.


PPM1H_HUMAN Protein phosphatase 1H (sprot)

A protein phosphatase 1H that is encoded in the genome of human.


PPM1J_HUMAN Protein phosphatase 1J (sprot)

A protein phosphatase 1J that is encoded in the genome of human.


PTN11_HUMAN Tyrosine-protein phosphatase non-receptor type 11 (sprot)

A tyrosine-protein phosphatase non-receptor type 11 that is encoded in the genome of human.


PTN12_HUMAN Tyrosine-protein phosphatase non-receptor type 12 (sprot)

A tyrosine-protein phosphatase non-receptor type 12 that is encoded in the genome of human.


PTN13_HUMAN Tyrosine-protein phosphatase non-receptor type 13 (sprot)

A tyrosine-protein phosphatase non-receptor type 13 that is encoded in the genome of human.


PTN14_HUMAN Tyrosine-protein phosphatase non-receptor type 14 (sprot)

A tyrosine-protein phosphatase non-receptor type 14 that is encoded in the genome of human.


PTN18_HUMAN Tyrosine-protein phosphatase non-receptor type 18 (sprot)

A tyrosine-protein phosphatase non-receptor type 18 that is encoded in the genome of human.


PTN1_HUMAN Tyrosine-protein phosphatase non-receptor type 1 (sprot)

A tyrosine-protein phosphatase non-receptor type 1 that is encoded in the genome of human.


PTN21_HUMAN Tyrosine-protein phosphatase non-receptor type 21 (sprot)

A tyrosine-protein phosphatase non-receptor type 21 that is encoded in the genome of human.


PTN22_HUMAN Tyrosine-protein phosphatase non-receptor type 22 (sprot)

A tyrosine-protein phosphatase non-receptor type 22 that is encoded in the genome of human.


PTN2_HUMAN Tyrosine-protein phosphatase non-receptor type 2 (sprot)

A tyrosine-protein phosphatase non-receptor type 2 that is encoded in the genome of human.


PTN3_HUMAN Tyrosine-protein phosphatase non-receptor type 3 (sprot)

A tyrosine-protein phosphatase non-receptor type 3 that is encoded in the genome of human.


PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (sprot)

A tyrosine-protein phosphatase non-receptor type 4 that is encoded in the genome of human.


PTN5_HUMAN Tyrosine-protein phosphatase non-receptor type 5 (sprot)

A tyrosine-protein phosphatase non-receptor type 5 that is encoded in the genome of human.


PTN9_HUMAN Tyrosine-protein phosphatase non-receptor type 9 (sprot)

A tyrosine-protein phosphatase non-receptor type 9 that is encoded in the genome of human.


PTPR2_HUMAN Receptor-type tyrosine-protein phosphatase N2 (sprot)

A receptor-type tyrosine-protein phosphatase N2 that is encoded in the genome of human.


PTPRB_HUMAN Receptor-type tyrosine-protein phosphatase beta (sprot)

A receptor-type tyrosine-protein phosphatase beta that is encoded in the genome of human.


PTPRD_HUMAN Receptor-type tyrosine-protein phosphatase delta (sprot)

A receptor-type tyrosine-protein phosphatase delta that is encoded in the genome of human.


PTPRE_HUMAN Receptor-type tyrosine-protein phosphatase epsilon (sprot)

A receptor-type tyrosine-protein phosphatase epsilon that is encoded in the genome of human.


PTPRF_HUMAN Receptor-type tyrosine-protein phosphatase F (sprot)

A receptor-type tyrosine-protein phosphatase F that is encoded in the genome of human.


PTPRG_HUMAN Receptor-type tyrosine-protein phosphatase gamma (sprot)

A receptor-type tyrosine-protein phosphatase gamma that is encoded in the genome of human.


PTPRJ_HUMAN Receptor-type tyrosine-protein phosphatase eta (sprot)

A receptor-type tyrosine-protein phosphatase eta that is encoded in the genome of human.


PTPRK_HUMAN Receptor-type tyrosine-protein phosphatase kappa (sprot)

A receptor-type tyrosine-protein phosphatase kappa that is encoded in the genome of human.


PTPRM_HUMAN Receptor-type tyrosine-protein phosphatase mu (sprot)

A receptor-type tyrosine-protein phosphatase mu that is encoded in the genome of human.


PTPRO_HUMAN Receptor-type tyrosine-protein phosphatase O (sprot)

A receptor-type tyrosine-protein phosphatase O that is encoded in the genome of human.


PTPRR_HUMAN Receptor-type tyrosine-protein phosphatase R (sprot)

A receptor-type tyrosine-protein phosphatase R that is encoded in the genome of human.


PTPRS_HUMAN Receptor-type tyrosine-protein phosphatase S (sprot)

A receptor-type tyrosine-protein phosphatase S that is encoded in the genome of human.


PTPRT_HUMAN Receptor-type tyrosine-protein phosphatase T (sprot)

A receptor-type tyrosine-protein phosphatase T that is encoded in the genome of human.


PTPRU_HUMAN Receptor-type tyrosine-protein phosphatase U (sprot)

A receptor-type tyrosine-protein phosphatase U that is encoded in the genome of human.


PTPRZ_HUMAN Receptor-type tyrosine-protein phosphatase zeta (sprot)

A receptor-type tyrosine-protein phosphatase zeta that is encoded in the genome of human.


SSH1_HUMAN Protein phosphatase Slingshot homolog 1 (sprot)

A protein phosphatase Slingshot homolog 1 that is encoded in the genome of human.


SSH2_HUMAN Protein phosphatase Slingshot homolog 2 (sprot)

A protein phosphatase Slingshot homolog 2 that is encoded in the genome of human.


TPTE_HUMAN Putative tyrosine-protein phosphatase TPTE (sprot)

A putative tyrosine-protein phosphatase TPTE that is encoded in the genome of human.


PTPC1_HUMAN Protein tyrosine phosphatase domain-containing protein 1 (sprot)

A protein tyrosine phosphatase domain-containing protein 1 that is encoded in the genome of human.


PTPRH_HUMAN Receptor-type tyrosine-protein phosphatase H (sprot)

A receptor-type tyrosine-protein phosphatase H that is encoded in the genome of human.


PTPRN_HUMAN Receptor-type tyrosine-protein phosphatase-like N (sprot)

A receptor-type tyrosine-protein phosphatase-like N that is encoded in the genome of human.


Q59FX6_HUMAN protein-tyrosine-phosphatase (Fragment) (trembl)


PTN23_HUMAN Tyrosine-protein phosphatase non-receptor type 23 (sprot)

A tyrosine-protein phosphatase non-receptor type 23 that is encoded in the genome of human.


CC14C_HUMAN Dual specificity protein phosphatase CDC14C (sprot)

A dual specificity protein phosphatase CDC14C that is encoded in the genome of human.


CTDS2_HUMAN Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (sprot)

A carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 that is encoded in the genome of human.


CTDSL_HUMAN CTD small phosphatase-like protein (sprot)

A CTD small phosphatase-like protein that is encoded in the genome of human.


DCPS_HUMAN m7GpppX diphosphatase (sprot)

A scavenger mRNA-decapping enzyme DcpS that is encoded in the genome of human.


DUS29_HUMAN Dual specificity phosphatase 29 (sprot)

A dual specificity phosphatase 29 that is encoded in the genome of human.


DUS22_HUMAN Dual specificity protein phosphatase 22 (sprot)

A dual specificity protein phosphatase 22 that is encoded in the genome of human.


DUS23_HUMAN Dual specificity protein phosphatase 23 (sprot)

A dual specificity protein phosphatase 23 that is encoded in the genome of human.


DUS26_HUMAN Dual specificity protein phosphatase 26 (sprot)

A dual specificity protein phosphatase 26 that is encoded in the genome of human.


LPIN1_HUMAN Phosphatidate phosphatase LPIN1 (sprot)

A phosphatidate phosphatase LPIN1 that is encoded in the genome of human.


LPIN2_HUMAN Phosphatidate phosphatase LPIN2 (sprot)

A phosphatidate phosphatase LPIN2 that is encoded in the genome of human.


LPIN3_HUMAN Phosphatidate phosphatase LPIN3 (sprot)

A phosphatidate phosphatase LPIN3 that is encoded in the genome of human.


DS13A_HUMAN Dual specificity protein phosphatase 13 isoform A (sprot)

A dual specificity protein phosphatase 13 (human), isoforms 2, 5, 6, 7, and 8.


ACP7_HUMAN Acid phosphatase type 7 (sprot)

An acid phosphatase type 7 that is encoded in the genome of human.


PPM1N_HUMAN Probable protein phosphatase 1N (sprot)

A probable protein phosphatase 1N that is encoded in the genome of human.


PTN20_HUMAN Tyrosine-protein phosphatase non-receptor type 20 (sprot)

A tyrosine-protein phosphatase non-receptor type 20 that is encoded in the genome of human.


PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ (sprot)

A phosphotidylinositol phosphatase PTPRQ that is encoded in the genome of human.


RPAP2_HUMAN Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 (sprot)

A putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 that is encoded in the genome of human.


SSH3_HUMAN Protein phosphatase Slingshot homolog 3 (sprot)

A protein phosphatase Slingshot homolog 3 that is encoded in the genome of human.


SSU72_HUMAN RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (sprot)

An RNA polymerase II subunit A C-terminal domain phosphatase SSU72 that is encoded in the genome of human.


UBS3B_HUMAN Ubiquitin-associated and SH3 domain-containing protein B (sprot)

A ubiquitin-associated and SH3 domain-containing protein B that is encoded in the genome of human.


VPS29_HUMAN Vacuolar protein sorting-associated protein 29 (sprot)

A vacuolar protein sorting-associated protein 29 that is encoded in the genome of human.


Phosphoric Acid

A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom.


L-dopachrome

The L-enantiomer of dopachrome.


Pyridoxamine

A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy.


S22AF_HUMAN Solute carrier family 22 member 15 (sprot)

A solute carrier family 22 member 15 that is encoded in the genome of human.


A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase.


S26A2_HUMAN Sulfate transporter (sprot)

A sulfate transporter that is encoded in the genome of human.


Sulfuric Acid

A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom.


Allopregnanolone

A 3-hydroxy-5alpha-pregnan-20-one in which the hydroxy group at position 3 has alpha-configuration. It is a metabolite of the sex hormone progesterone and used for the treatment of postpartum depression in women.


ODPX_HUMAN Pyruvate dehydrogenase protein X component, mitochondrial (sprot)

A pyruvate dehydrogenase protein X component, mitochondrial that is encoded in the genome of human.


Lipoic acid

The (R)-enantiomer of lipoic acid. A vitamin-like, C8 thia fatty acid with anti-oxidant properties.


thromboxane A2

A thromboxane which is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation.


Thiocyanate

A pseudohalide anion obtained by deprotonation of the thiol group of thiocyanic acid.


O,O-Diethyl hydrogen thiophosphate

An organic thiophosphate that is the diethyl ester of phosphorothioic O,O,O-acid.


N,N-Dimethylaniline N-oxide

A member of the class of dimethylanilines that is N,N-dimethylaniline in which the tertiary amino group has been oxidised to give the corresponding N-oxide.


NGBR_HUMAN Dehydrodolichyl diphosphate synthase complex subunit NUS1 (sprot)

A dehydrodolichyl diphosphate synthase complex subunit NUS1 that is encoded in the genome of human.


Q5T0A0_HUMAN ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] (trembl)


Q5T0A2_HUMAN Alkyl transferase (Fragment) (trembl)


Q5T0A3_HUMAN Alkyl transferase (Fragment) (trembl)


Q5T0A6_HUMAN ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] (Fragment) (trembl)


Undecaprenyl pyrophosphate

The all-trans-isomer of undecaprenyl diphosphate.


2,3-Dimethylacrylic acid, (E)-

A 2-methylbut-2-enoic acid having its double bond in trans-configuration.


Epipregnanolone

The 3beta-stereoisomer of 3-hydroxy-5beta-pregnan-20-one.


Dihydroxyacetone phosphate

A member of the class of glycerone phosphates that consists of glycerone bearing a single phospho substituent.


3-Hydroxyanthranilic acid

An  aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.


A 2-amino-1-hydroxyoctadecan-3-one that has S-configuration.


acetoacetyl-CoA

A 3-oxoacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of acetoacetic acid.


Octane

A straight chain alkane composed of 8 carbon atoms.


NDUBA_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 that is encoded in the genome of human.


NDUB2_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial that is encoded in the genome of human.


NDUV3_HUMAN NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial that is encoded in the genome of human.


NDUC1_HUMAN NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial that is encoded in the genome of human.


NDUB6_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 that is encoded in the genome of human.


NDUB8_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial that is encoded in the genome of human.


CYB5B_HUMAN Cytochrome b5 type B (sprot)

A cytochrome b5 type B that is encoded in the genome of human.


CIA30_HUMAN Complex I intermediate-associated protein 30, mitochondrial (sprot)

A complex I intermediate-associated protein 30, mitochondrial that is encoded in the genome of human.


ECSIT_HUMAN Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (sprot)

An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of human.


NDUF4_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 that is encoded in the genome of human.


NDUF2_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 that is encoded in the genome of human.


A coenzyme found in all living cells; consists of two nucleotides joined through their 5'-phosphate groups, with one nucleotide containing an adenine base and the other containing nicotinamide.


HCAR3_HUMAN Hydroxycarboxylic acid receptor 3 (sprot)

A hydroxycarboxylic acid receptor 3 that is encoded in the genome of human.


HCAR2_HUMAN Hydroxycarboxylic acid receptor 2 (sprot)

A hydroxycarboxylic acid receptor 2 that is encoded in the genome of human.


Nicotinic acid

A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.


The 1-phospho derivative of alpha-D-ribose.


GADL1_HUMAN Acidic amino acid decarboxylase GADL1 (sprot)

An acidic amino acid decarboxylase GADL1 that is encoded in the genome of human.


PDXD1_HUMAN Pyridoxal-dependent decarboxylase domain-containing protein 1 (sprot)

A pyridoxal-dependent decarboxylase domain-containing protein 1 that is encoded in the genome of human.


PDXD2_HUMAN Putative pyridoxal-dependent decarboxylase domain-containing protein 2 (sprot)


THNS2_HUMAN Threonine synthase-like 2 (sprot)

A threonine synthase-like 2 that is encoded in the genome of human.


A1L4G7_HUMAN Tyrosine aminotransferase (trembl)


Q53ET7_HUMAN Serine hydroxymethyltransferase (Fragment) (trembl)


Q53Y41_HUMAN Dopa decarboxylase (Aromatic L-amino acid decarboxylase) (trembl)


Q59GM9_HUMAN Alpha-1,4 glucan phosphorylase (Fragment) (trembl)


Q5JAM2_HUMAN 5-aminolevulinate synthase (trembl)


Q5VZ30_HUMAN Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) (trembl)


Q86V02_HUMAN CSAD protein (Fragment) (trembl)


Q8IVA8_HUMAN Glutamate decarboxylase 1 (Brain, 67kDa) (trembl)


Q8TDG6_HUMAN Alpha-1,4 glucan phosphorylase (Fragment) (trembl)


Q96JQ3_HUMAN p-selectin cytoplasmic tail-associated protein (PCAP) (trembl)


Q9UGI5_HUMAN Glutamic acid decarboxylase (Fragment) (trembl)


Pyridoxal phosphate

The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.


gamma-Tocopherol

A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 3-methylbut-2-enoic acid.


Acetylphosphate

An acyl monophosphate in which the acyl group specified is acetyl.


The 7alpha-hydroxy derivative of cholesterol.


A tertiary amine oxide resulting from the oxidation of the pyrrolidine nitrogen of nicotine.


Benzene

A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system.


A purine 2'-deoxyribonucleoside 5'-diphosphate having adenine as the nucleobase.


20-Hydroxy-leukotriene B4

The 20-hydroxy derivative of leukotriene B4.


Bupropion

An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.


Phosphocreatine

A phosphoamino acid consisting of creatine having a phospho group attached at the primary nitrogen of the guanidino group.


Thiamine triphosphate

A thiamine phosphate that is thiamine(1+) in which the hydroxy group is replaced by a triphosphate group. It is found in low amounts in most vertebrate tissues and can phosphorylate certain proteins.


A di-N-acetylchitobiase that is encoded in the genome of human.


NGLY1_HUMAN Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase (sprot)

A peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase that is encoded in the genome of human.


D-Glucosamine

A D-glucosamine whose structure comprises D-glucopyranose having an amino substituent at position 2.


AICA ribonucleotide

A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative.


Flavin mononucleotide

A flavin mononucleotide that is riboflavin (vitamin B2) in which the primary hydroxy group has been converted to its dihydrogen phosphate ester.


Q96HI4_HUMAN Glycylpeptide N-tetradecanoyltransferase (Fragment) (trembl)


Q5VUC7_HUMAN Glycylpeptide N-tetradecanoyltransferase (trembl)


Q5VUC6_HUMAN Glycylpeptide N-tetradecanoyltransferase (trembl)


A4FU65_HUMAN Glycylpeptide N-tetradecanoyltransferase (Fragment) (trembl)


Methylguanidine

A guanidine in which one of the amino hydrogens of guanidine itself is substituted by a methyl group.


CYC_HUMAN Cytochrome c (sprot)

A cytochrome c, somatic that is encoded in the genome of human.


Imidazole

An imidazole tautomer which has the migrating hydrogen at position 1.


3-(Methylthio)propionic acid

A thia fatty acid acid consisting of propionic acid with a methylthio substituent at the 3-position; an intermediate in mammalian methionine metabolism in vitro. The simplest known phytotoxin, it is a blight-inducing toxin produced by the cassava pathogen Xanthomonas campestris manihotis.


APAF_HUMAN Apoptotic protease-activating factor 1 (sprot)

An apoptotic protease-activating factor 1 that is encoded in the genome of human.


2'-Deoxyadenosine 5'-triphosphate

A purine 2'-deoxyribonucleoside 5'-triphosphate having adenine as the nucleobase.


N,N-dimethylarginine

A L-arginine derivative  having two methyl groups both attached to the primary amino moiety of the guanidino group.


N-acetyllactosamine

A beta-D-galactopyranosyl-(1->4)-N-acetyl-D-glucosamine having beta-configuration at the reducing end anomeric centre.


Pyridoxal

A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid.


A pyrimidine ribonucleoside 5'-diphosphate having cytosine as the nucleobase.


DEF4_HUMAN Defensin alpha 4 (sprot)

A protein that is a translation product of the DEFA4 gene in human.


Corticosterone

A 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.


A6NMS2_HUMAN Phosphoribosyl pyrophosphate synthetase 2 (Fragment) (trembl)


Q53FW2_HUMAN ribose-phosphate diphosphokinase (Fragment) (trembl)


A D-ribofuranose 5-phosphate with an alpha-configuration at anomeric position.


S-Formylglutathione

A S-acylglutathione in which the acyl group specified is formyl.


4-(Methylsulfanyl)-2-oxobutanoic acid

A 2-oxo monocarboxylic acid derived from L-methionine via the action of methionine transaminase.


A purine ribonucleoside 5'-monophosphate having xanthine as the nucleobase.


Pyridoxamine phosphate

A vitamin B6 phosphate that is the  phosphoric ester derivative of pyridoxamine.


Levoleucovorin

The pharmacologically active (6S)-stereoisomer of 5-formyltetrahydrofolic acid.


Guanosine substituted with a methyl group at position N-1.


CDP-ethanolamine

A phosphoethanolamine consisting of ethanolamine having a cytidine 5'-diphosphate moiety attached to the oxygen.


ESPB1_HUMAN Epididymal sperm-binding protein 1 (sprot)

An epididymal sperm-binding protein 1 that is encoded in the genome of human.


Phosphocholine

The phosphate of choline; and the parent compound of the phosphocholine family.


trans-2-Octenoic acid

An olefinic fatty acid that is octanoic acid carrying a double bond at position 2 (the 2E-isomer).


A D-glucopyranose 1-phosphate in which the anomeric centre has alpha-configuration.


pentosuria

Pentosuria is an inborn error of metabolism which is characterized by the excretion of 1 to 4 g of the pentose L-xylulose in the urine per day.


Acetone

A methyl ketone that consists of propane bearing an oxo group at C2.


3'-Hydroxycinnamic acid

A 3-coumaric acid that is phenol substituted with trans-2-propenoic acid at position C-3.


dl-O-Phosphoserine

A serine derivative that is serine substituted at the oxygen atom by a phosphono group.


PRGR_HUMAN Progesterone receptor (sprot)

A progesterone receptor that is encoded in the genome of human.


CENPR_HUMAN Centromere protein R (sprot)

A centromere protein R that is encoded in the genome of human.


FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP5 that is encoded in the genome of human.


Q6TZ08_HUMAN Progesterone receptor (Fragment) (trembl)


Progesterone

A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.


Guanidine

An aminocarboxamidine, the parent compound of the guanidines.


(S)-(-)-Methylsuccinic acid

A 2-methylbutanedioic acid in which the methyl group at position 2 has S-configuration.


Caffeine

A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee.


Imipramine

A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.


Propranolol

A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.


Verapamil

A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.


L-arabinitol

The L-enantiomer of arabinitol.


RARG_HUMAN Retinoic acid receptor gamma (sprot)

A retinoic acid receptor gamma that is encoded in the genome of human.


TIG1_HUMAN Retinoic acid receptor responder protein 1 (sprot)

A retinoic acid receptor responder protein 1 that is encoded in the genome of human.


RARA_HUMAN Retinoic acid receptor alpha (sprot)

A retinoic acid receptor alpha that is encoded in the genome of human.


RARB_HUMAN Retinoic acid receptor beta (sprot)

A retinoic acid receptor beta that is encoded in the genome of human.


RXRB_HUMAN Retinoic acid receptor RXR-beta (sprot)

A retinoic acid receptor RXR-beta that is encoded in the genome of human.


RXRG_HUMAN Retinoic acid receptor RXR-gamma (sprot)

A retinoic acid receptor RXR-gamma that is encoded in the genome of human.


RABP1_HUMAN Cellular retinoic acid-binding protein 1 (sprot)

A cellular retinoic acid-binding protein 1 that is encoded in the genome of human.


RXRA_HUMAN Retinoic acid receptor RXR-alpha (sprot)

A retinoic acid receptor RXR-alpha that is encoded in the genome of human.


RABP2_HUMAN Cellular retinoic acid-binding protein 2 (sprot)

A cellular retinoic acid-binding protein 2 that is encoded in the genome of human.


NCOR2_HUMAN Nuclear receptor corepressor 2 (sprot)

A nuclear receptor corepressor 2 that is encoded in the genome of human.


Tretinoin

A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.


3,4-Dihydroxybenzoic acid

A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.


1,3-Dimethyluric acid

An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trionesubstituted by methyl groups at N-1 and N-3.


P-Cresol

A cresol that consists of toluene substituted by a hydroxy group at position 4. It is a metabolite of aromatic amino acid metabolism produced by intestinal microflora in humans and animals.


Acetaminophen

A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.


Paraxanthine

A dimethylxanthine having the two methyl groups located at positions 1 and 7. It is a metabolite of caffeine and theobromine in animals.


2-Ethylacrylic acid

An alpha,beta-unsaturated monocarboxylic acid that is acrylic acid in which the hydrogen at position 2 is substituted by an ethyl group.


2-Hydroxypentanoic acid

A 2-hydroxy monocarboxylic acid that is valeric (pentanoic) acid substituted at the alpha-position by a hydroxy group.


3,4-Dihydroxymandelic acid

A catechol that is the 3,4-dihydroxy derivative of mandelic acid; a metabolite of L-dopa.


Aminohippuric acid

An N-acylglycine that is the 4-amino derivative of hippuric acid; used as a diagnostic agent in the measurement of renal plasma flow.


Benzoic Acid

A compound comprising a benzene ring core carrying a carboxylic acid substituent.


Epicatechin

A catechin with (2R,3R)-configuration.


Isobutyric acid

A branched fatty acid comprising propanoic acid carrying a methyl branch at C-2.


PPME1_HUMAN Protein phosphatase methylesterase 1 (sprot)

A protein phosphatase methylesterase 1 that is encoded in the genome of human.


Methanol

The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group.


Valproic Acid

A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.


Thymol

A phenol that is a natural monoterpene derivative of cymene.


Aspirin

A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.


Dihydroxyacetone

A ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones.


N,N-Dimethylformamide

A member of the class of formamides that is formamide in which the amino hydrogens are replaced by methyl groups.


Theophylline

A dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea.


Acetylcysteine

An  N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.


PROS_HUMAN Vitamin K-dependent protein S (sprot)

A vitamin K-dependent protein S that is encoded in the genome of human.


PROZ_HUMAN Vitamin K-dependent protein Z (sprot)

A vitamin K-dependent protein Z that is encoded in the genome of human.


VKOR1_HUMAN Vitamin K epoxide reductase complex subunit 1 (sprot)

A vitamin K epoxide reductase complex subunit 1 that is encoded in the genome of human.


VKORL_HUMAN Vitamin K epoxide reductase complex subunit 1-like protein 1 (sprot)

A vitamin K epoxide reductase complex subunit 1-like protein 1 that is encoded in the genome of human.


Menadione

A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia.


familial isolated deficiency of vitamin E

Ataxia with vitamin E deficiency (AVED) is a neurodegenerative disease belonging to the inherited cerebellar ataxias. It is mainly characterized by progressive spino-cerebellar ataxia, loss of proprioception, areflexia, and is associated with a marked deficiency in vitamin E.


TTPA_HUMAN Alpha-tocopherol transfer protein (sprot)

An alpha-tocopherol transfer protein that is encoded in the genome of human.


Alpha-Tocopherol

An alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils.


TS1R3_HUMAN Taste receptor type 1 member 3 (sprot)

A taste receptor type 1 member 3 that is encoded in the genome of human.


TS1R2_HUMAN Taste receptor type 1 member 2 (sprot)

A taste receptor type 1 member 2 that is encoded in the genome of human.


Aspartame

A dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener.


Salicylic Acid

A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves.


migraine with or without aura, susceptibility to, 1


A five-membered form of ribonolactone having D-configuration.


Aminocaproic acid

An epsilon-amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator.


Calcitriol

A hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give calcitriol.


2-Aminoisobutyric acid

A rare, non-protein amino acid and end-product of pyrimidine metabolism, excreted in urine and found in some antibiotics of fungal origin. With the exception of a few bacteria, it is non-metabolisable, and therefore used in bioassays.


Omeprazole

A member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a [4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl group at position 2 and a methoxy group at position 5.


Alendronic acid

A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.


Digoxin

A  cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.


Levomethorphan

A 6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene in which the stereocenters at positions 4a, 10 and 10a have R-configuration. It is a prodrug of levorphanol and a strong narcotic analgesic, and listed as a schedule II controlled substance.


Metformin

A member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1.


ADAM9_HUMAN Disintegrin and metalloproteinase domain-containing protein 9 (sprot)

A disintegrin and metalloproteinase domain-containing protein 9 that is encoded in the genome of human.


AT5EL_HUMAN ATP synthase subunit epsilon-like protein, mitochondrial (sprot)

An ATP synthase subunit epsilon-like protein, mitochondrial that is encoded in the genome of human.


Clotrimazole

A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group.


Naproxen

A methoxynaphthalene that is 2-methoxynaphthalene substituted by a carboxy ethyl group at position 6. Naproxen is a non-steroidal anti-inflammatory drug commonly used for the reduction of pain, fever, inflammation  and stiffness caused by conditions such as osteoarthritis, kidney stones, rheumatoid arthritis, psoriatic arthritis, gout, ankylosing spondylitis, menstrual cramps, tendinitis, bursitis, and for the treatment of primary dysmenorrhea. It works by inhibiting both the COX-1 and COX-2 enzymes.


Atenolol

An ethanolamine compound having a (4-carbamoylmethylphenoxy)methyl group at the 1-position and an N-isopropyl substituent.


Ibuprofen

A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group.


Ethinyl estradiol

A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a  xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.


Diphenhydramine

An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.


Hydrochlorothiazide

A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.


TOP2A_HUMAN DNA topoisomerase 2-alpha (sprot)

A DNA topoisomerase 2-alpha that is encoded in the genome of human.


Levofloxacin

An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase.


Ranitidine hydrochloride

A member of the class of  furans used to treat  peptic ulcer disease (PUD) and gastroesophageal reflux disease.


Metoprolol

A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a  4-(2-methoxyethyl)phenoxy group at position 1.


Furosemide

A  chlorobenzoic acid that is 4-chlorobenzoic acid substituted by a (furan-2-ylmethyl)amino and a sulfamoyl group at position 2 and 5 respectively. It is a diuretic used in the treatment of congestive heart failure.


Nicotine

A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.


Warfarin

A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.


ACM1_HUMAN Muscarinic acetylcholine receptor M1 (sprot)

A muscarinic acetylcholine receptor M1 that is encoded in the genome of human.


IL8_HUMAN Interleukin-8 (sprot)

An interleukin-8 that is encoded in the genome of human.


Salbutamol

A member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD).


ANGT_HUMAN Angiotensinogen (sprot)

An angiotensinogen that is encoded in the genome of human.


Medroxyprogesterone

A 3-oxo Delta(4)-steroid that is pregn-4-ene-3,20-dione substituted by an alpha-hydroxy group at position 17 and a methyl group at position 6.


Triamterene

Pteridine substituted at positions 2, 4 and 7 with amino groups and at position 6 with a phenyl group. A sodium channel blocker, it is used as a diuretic in the treatment of hypertension and oedema.


Brompheniramine

Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.


Phenylpropanolamine

An amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2R-stereoisomer).


Pseudoephedrine

A member of the class of the class of phenylethanolamines that is (1S)-2-(methylamino)-1-phenylethan-1-ol in which the pro-S hydrogen at position 2 is replaced by a methyl group.


Chlorpheniramine

A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.


(3S)-3-hydroxyoctanoic acid

The (S)-enantiomer of 3-hydroxyoctanoic acid.


3-Phenylbutyric acid

A monocarboxylic acid that is butanoic acid substituted by a phenyl group at position 3.


Caffeic Acid

The trans-isomer of caffeic acid.


DOPD_HUMAN D-dopachrome decarboxylase (sprot)

A D-dopachrome decarboxylase that is encoded in the genome of human.


Carbon Dioxide

A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food.


AAAD_HUMAN Arylacetamide deacetylase (sprot)

An arylacetamide deacetylase that is encoded in the genome of human.


A4Z6T8_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6T9_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6U4_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6U6_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6U7_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6U9_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6V9_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6Y1_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6Y3_HUMAN arylamine N-acetyltransferase (trembl)


A4Z6Y5_HUMAN arylamine N-acetyltransferase (trembl)


A4Z737_HUMAN arylamine N-acetyltransferase (trembl)


A4Z787_HUMAN arylamine N-acetyltransferase (trembl)


A4Z7F6_HUMAN arylamine N-acetyltransferase (trembl)


A4Z7H3_HUMAN arylamine N-acetyltransferase (trembl)


A4Z7J7_HUMAN arylamine N-acetyltransferase (trembl)


A4Z7K4_HUMAN arylamine N-acetyltransferase (trembl)


A4Z7P9_HUMAN arylamine N-acetyltransferase (trembl)


A4Z7V0_HUMAN arylamine N-acetyltransferase (trembl)


A4Z867_HUMAN arylamine N-acetyltransferase (trembl)


Q400I7_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q400J6_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q6U7I7_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q9HAQ5_HUMAN arylamine N-acetyltransferase (trembl)


A9X868_HUMAN arylamine N-acetyltransferase (trembl)


A9X7X6_HUMAN arylamine N-acetyltransferase (trembl)


A9X7Q9_HUMAN arylamine N-acetyltransferase (trembl)


A9X854_HUMAN arylamine N-acetyltransferase (trembl)


A9X844_HUMAN arylamine N-acetyltransferase (trembl)


A9X7U6_HUMAN arylamine N-acetyltransferase (trembl)


A9X816_HUMAN arylamine N-acetyltransferase (trembl)


Q1HRY2_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q1HRY6_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q09LL5_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q5C8V2_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q1HRY5_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q1HRY3_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Q1HRY4_HUMAN arylamine N-acetyltransferase (Fragment) (trembl)


Osbond acid

The all-cis-isomer of a C22 polyunsaturated fatty acid having five double bonds in the 4-, 7-, 10-, 13- and 16-positions. It is a member of n-6 PUFA and a product of linoleic acid metabolism.


V2R_HUMAN Vasopressin V2 receptor (sprot)

A vasopressin V2 receptor that is encoded in the genome of human.


CUL5_HUMAN Cullin-5 (sprot)

A cullin-5 that is encoded in the genome of human.


NPSR1_HUMAN Neuropeptide S receptor (sprot)

A neuropeptide S receptor that is encoded in the genome of human.


Q9UEW6_HUMAN Vasopressin-neurophysin (Fragment) (trembl)


Q3S2J4_HUMAN Vasopressin V1a receptor (trembl)


Q9UH72_HUMAN V1-vascular vasopressin receptor AVPR1A (Fragment) (trembl)


Q16271_HUMAN Arginine vasopressin V2 receptor (Fragment) (trembl)


3,7-Dimethyluric acid

An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trione substituted by methyl groups at N-3 and N-7.


A 5'-deoxyribonucleoside compound having adenosine as the nucleobase.


Finasteride

An aza-steroid that is a synthetic drug for the treatment of benign prostatic hyperplasia.


2-Hydroxy-2-methylbutyric acid

A branched-chain fatty acid that is 2-methylbutyric acid substituted at C-2 by a hydroxy group.


An oxopurine that is xanthine in which the hydrogen attached to the nitrogen at position 7 is replaced by a methyl group. It is an intermediate metabolite in the synthesis of caffeine.


A cholestanoid consisting of a cholesterol core having an oxo group at the 3-position, a C=C bond at the 4,5-position and an alpha-hydroxy group at the 7-position.


Icosapent

An icosapentaenoic acid having five cis-double bonds at positions 5, 8, 11, 14 and 17.


Myristoleic acid

A tetradecenoic acid in which the double bond is at the 9-10 position and has Z configuration. Myristoleic acid has been isolated from Serenoa repens and has cytotoxic and apoptosis-inducing effects.


Tetracosanoic acid

A C24 straight-chain saturated fatty acid.


A tryptamine alkaloid that is N,N-dimethyltryptamine substituted by a methoxy group at position 5.


crotonoyl-CoA

The (E)-isomer of but-2-enoyl-CoA.


A compound composed of the standard 2,3-dimethoxy-5-methylbenzoquinone nucleus common to ubiquinones; and a side chain of a single isoprenoid unit.


Butyrylcarnitine

An optically active form of O-butanoylcarnitine having L-configuration.


An O-acylcarnitine having (5Z)-tetradecenoyl as the acyl substituent.


A phenylethylamine that is ethylamine substituted by a phenyl group at position 1.


Phytol

A diterpenoid that is hexadec-2-en-1-ol substituted by methyl groups at positions 3, 7, 11 and 15.


IMIDAZOLEACETIC ACID

A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by an imidazol-4-yl group.


A fructosamine-3-kinase that is encoded in the genome of human.


KT3K_HUMAN Ketosamine-3-kinase (sprot)

A ketosamine-3-kinase that is encoded in the genome of human.


TDG_HUMAN G/T mismatch-specific thymine DNA glycosylase (sprot)

A G/T mismatch-specific thymine DNA glycosylase that is encoded in the genome of human.


An oxopurine that is guanine in which the hydrogen at position 8 is replaced by an oxo group and in which the nitrogens at positions 7 and 9 each bear a hydrogen.


p-Coumaric acid

The trans-isomer of 4-coumaric acid.


o-Cresol

A cresol that is phenol substituted by a methyl group at position 2. It is a minor urinary metabolite of toluene.


AMACR_HUMAN Alpha-methylacyl-CoA racemase (sprot)

An alpha-methylacyl-CoA racemase that is encoded in the genome of human.


pristanoyl-CoA

A multi-methyl-branched fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of pristanic acid.


CD44_HUMAN CD44 antigen (sprot)

A CD44 molecule that is encoded in the genome of human.


PGCA_HUMAN Aggrecan core protein (sprot)

An aggrecan core protein that is encoded in the genome of human.


TSG6_HUMAN Tumor necrosis factor-inducible gene 6 protein (sprot)

A tumor necrosis factor-inducible gene 6 protein that is encoded in the genome of human.


PGCB_HUMAN Brevican core protein (sprot)

A brevican core protein that is encoded in the genome of human.


CSPG2_HUMAN Versican core protein (sprot)

A versican core protein that is encoded in the genome of human.


U17LO_HUMAN Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 (sprot)

A ubiquitin carboxyl-terminal hydrolase 17-like protein 24 that is encoded in the genome of human.


HMMR_HUMAN Hyaluronan mediated motility receptor (sprot)

A hyaluronan mediated motility receptor that is encoded in the genome of human.


STAB2_HUMAN Stabilin-2 (sprot)

A stabilin-2 that is encoded in the genome of human.


IMPG2_HUMAN Interphotoreceptor matrix proteoglycan 2 (sprot)

An interphotoreceptor matrix proteoglycan 2 that is encoded in the genome of human.


LYVE1_HUMAN Lymphatic vessel endothelial hyaluronic acid receptor 1 (sprot)

A lymphatic vessel endothelial hyaluronic acid receptor 1 that is encoded in the genome of human.


HPLN1_HUMAN Hyaluronan and proteoglycan link protein 1 (sprot)

A hyaluronan and proteoglycan link protein 1 that is encoded in the genome of human.


HPLN2_HUMAN Hyaluronan and proteoglycan link protein 2 (sprot)

A hyaluronan and proteoglycan link protein 2 that is encoded in the genome of human.


HPLN3_HUMAN Hyaluronan and proteoglycan link protein 3 (sprot)

A hyaluronan and proteoglycan link protein 3 that is encoded in the genome of human.


HPLN4_HUMAN Hyaluronan and proteoglycan link protein 4 (sprot)

A hyaluronan and proteoglycan link protein 4 that is encoded in the genome of human.


STAB1_HUMAN Stabilin-1 (sprot)

A stabilin-1 that is encoded in the genome of human.


LAYN_HUMAN Layilin (sprot)

A layilin that is encoded in the genome of human.


SUSD5_HUMAN Sushi domain-containing protein 5 (sprot)

A sushi domain-containing protein 5 that is encoded in the genome of human.


HABP2_HUMAN Hyaluronan-binding protein 2 (sprot)

A hyaluronan-binding protein 2 that is encoded in the genome of human.


An amino disaccharide consisting of 2-acetamido-beta-D-glucopyranose and beta-D-glucopyranuronic acid residues joined in sequence by a (1->4)-glycosidic bond.


N-acetylputrescine

An N-monoacetylalkane-alpha,omega-diamine that is the N-monoacetyl derivative of putrescine.


Erucic Acid

A docosenoic acid having a cis- double bond at C-13. It is found particularly in brassicas - it is a major component of mustard and rapeseed oils and is produced by broccoli, Brussels sprouts, kale, and wallflowers.


4-Hydroxy-2-oxoglutaric acid

An oxo dicarboxylic acid comprising glutaric acid having oxo- and hydroxy substituents at the 2- and 4-positions respectively.


Bisnorcholic acid

A bile acid that is 24-dinor-5beta-cholan-22-oic acid bearing three hydroxy substituents at positions 3alpha, 7alpha and 12alpha.


Cyanide ion

A pseudohalide anion that is the conjugate base of hydrogen cyanide.


Syringic acid

A dimethoxybenzene that is 3,5-dimethyl ether derivative of gallic acid.


Adenosylcobalamin

A member of the class of cobalamins that is vitamin B12 in which the cyano group is replaced by a 5'-deoxyadenos-5'-yl moiety. It is one of the two metabolically active form of vitamin B12.


Isovalerylsarcosine

An N-acyl-amino acid resulting from the formal condensation of carboxy group of isovaleric acid with the amino group of sarcosine.


n-Oleoylethanolamine

An N-(long-chain-acyl)ethanolamine that is the ethanolamide of oleic acid. The monounsaturated analogue of the endocannabinoid anandamide.


Itaconic acid

A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.


Malonylcarnitine

An O-acyl-L-carnitine in which the acyl group is specified as malonyl.


B2MG_HUMAN Beta-2-microglobulin (sprot)

A beta-2-microglobulin that is encoded in the genome of human.


Indole-3-butyric acid

A indol-3-yl carboxylic acid that is butanoic acid carrying a 1H-indol-3-yl substituent at position 1.


Palmitoylethanolamide

An N-(long-chain-acyl)ethanolamine that is the ethanolamide of palmitic (hexadecanoic) acid.


A 26-hydroxycholesterol in which the 25-position has R-configuration.


(2S)-2-amino-5-oxopentanoic acid

A glutamic semialdehyde arising from formal reduction of the side-chain carboxy group of L-glutamic acid.


Phthalic acid

A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.


PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondrial (sprot)

A peptidyl-tRNA hydrolase 2, mitochondrial that is encoded in the genome of human.


AOAH_HUMAN Acyloxyacyl hydrolase (sprot)

An acyloxyacyl hydrolase that is encoded in the genome of human.


HYEP_HUMAN Epoxide hydrolase 1 (sprot)

An epoxide hydrolase 1 that is encoded in the genome of human.


RPE65_HUMAN Retinoid isomerohydrolase (sprot)

A retinal pigment epithelium-specific 65 kDa protein that is encoded in the genome of human.


MOC2B_HUMAN Molybdopterin synthase catalytic subunit (sprot)

A molybdopterin synthase catalytic subunit that is encoded in the genome of human.


CN37_HUMAN 2',3'-cyclic-nucleotide 3'-phosphodiesterase (sprot)

A 2',3'-cyclic-nucleotide 3'-phosphodiesterase that is encoded in the genome of human.


CYLD_HUMAN Ubiquitin carboxyl-terminal hydrolase CYLD (sprot)

A ubiquitin carboxyl-terminal hydrolase CYLD that is encoded in the genome of human.


PRDX5_HUMAN Peroxiredoxin-5, mitochondrial (sprot)

A peroxiredoxin-5, mitochondrial that is encoded in the genome of human.


AQP3_HUMAN Aquaporin-3 (sprot)

An aquaporin-3 that is encoded in the genome of human.


PTH_HUMAN Peptidyl-tRNA hydrolase (sprot)

A probable peptidyl-tRNA hydrolase PTRH1 that is encoded in the genome of human.


AQP2_HUMAN Aquaporin-2 (sprot)

An aquaporin-2 that is encoded in the genome of human.


PRDX1_HUMAN Peroxiredoxin-1 (sprot)

A peroxiredoxin-1 that is encoded in the genome of human.


PRDX3_HUMAN Thioredoxin-dependent peroxide reductase, mitochondrial (sprot)

A thioredoxin-dependent peroxide reductase, mitochondrial that is encoded in the genome of human.


PRDX4_HUMAN Peroxiredoxin-4 (sprot)

A peroxiredoxin-4 that is encoded in the genome of human.


UBP16_HUMAN Ubiquitin carboxyl-terminal hydrolase 16 (sprot)

A ubiquitin carboxyl-terminal hydrolase 16 that is encoded in the genome of human.


STABP_HUMAN STAM-binding protein (sprot)

A STAM-binding protein that is encoded in the genome of human.


UBP51_HUMAN Ubiquitin carboxyl-terminal hydrolase 51 (sprot)

A ubiquitin carboxyl-terminal hydrolase 51 that is encoded in the genome of human.


UBP33_HUMAN Ubiquitin carboxyl-terminal hydrolase 33 (sprot)

A ubiquitin carboxyl-terminal hydrolase 33 that is encoded in the genome of human.


UBP22_HUMAN Ubiquitin carboxyl-terminal hydrolase 22 (sprot)

A ubiquitin carboxyl-terminal hydrolase 22 that is encoded in the genome of human.


UBP47_HUMAN Ubiquitin carboxyl-terminal hydrolase 47 (sprot)

A ubiquitin carboxyl-terminal hydrolase 47 that is encoded in the genome of human.


UBP40_HUMAN Ubiquitin carboxyl-terminal hydrolase 40 (sprot)

A ubiquitin carboxyl-terminal hydrolase 40 that is encoded in the genome of human.


UBP35_HUMAN Ubiquitin carboxyl-terminal hydrolase 35 (sprot)

A ubiquitin carboxyl-terminal hydrolase 35 that is encoded in the genome of human.


UBP36_HUMAN Ubiquitin carboxyl-terminal hydrolase 36 (sprot)

A ubiquitin carboxyl-terminal hydrolase 36 that is encoded in the genome of human.


UBP29_HUMAN Ubiquitin carboxyl-terminal hydrolase 29 (sprot)

A ubiquitin carboxyl-terminal hydrolase 29 that is encoded in the genome of human.


UBP46_HUMAN Ubiquitin carboxyl-terminal hydrolase 46 (sprot)

A ubiquitin carboxyl-terminal hydrolase 46 that is encoded in the genome of human.


Q08AK7_HUMAN Ubiquitin carboxyl-terminal hydrolase (trembl)


UBP1_HUMAN Ubiquitin carboxyl-terminal hydrolase 1 (sprot)

A ubiquitin carboxyl-terminal hydrolase 1 that is encoded in the genome of human.


UBP7_HUMAN Ubiquitin carboxyl-terminal hydrolase 7 (sprot)

A ubiquitin carboxyl-terminal hydrolase 7 that is encoded in the genome of human.


UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolase 5 (sprot)

A ubiquitin carboxyl-terminal hydrolase 5 that is encoded in the genome of human.


USP9X_HUMAN Probable ubiquitin carboxyl-terminal hydrolase FAF-X (sprot)

A probable ubiquitin carboxyl-terminal hydrolase FAF-X that is encoded in the genome of human.


USP9Y_HUMAN Probable ubiquitin carboxyl-terminal hydrolase FAF-Y (sprot)

A probable ubiquitin carboxyl-terminal hydrolase FAF-Y that is encoded in the genome of human.


UBP26_HUMAN Ubiquitin carboxyl-terminal hydrolase 26 (sprot)

A ubiquitin carboxyl-terminal hydrolase 26 that is encoded in the genome of human.


UBP42_HUMAN Ubiquitin carboxyl-terminal hydrolase 42 (sprot)

A ubiquitin carboxyl-terminal hydrolase 42 that is encoded in the genome of human.


UBP32_HUMAN Ubiquitin carboxyl-terminal hydrolase 32 (sprot)

A ubiquitin carboxyl-terminal hydrolase 32 that is encoded in the genome of human.


UBP30_HUMAN Ubiquitin carboxyl-terminal hydrolase 30 (sprot)

A ubiquitin carboxyl-terminal hydrolase 30 that is encoded in the genome of human.


UBP13_HUMAN Ubiquitin carboxyl-terminal hydrolase 13 (sprot)

A ubiquitin carboxyl-terminal hydrolase 13 that is encoded in the genome of human.


A6NJA2_HUMAN Ubiquitin carboxyl-terminal hydrolase (trembl)


UBP6_HUMAN Ubiquitin carboxyl-terminal hydrolase 6 (sprot)

A ubiquitin carboxyl-terminal hydrolase 6 that is encoded in the genome of human.


UBP10_HUMAN Ubiquitin carboxyl-terminal hydrolase 10 (sprot)

A ubiquitin carboxyl-terminal hydrolase 10 that is encoded in the genome of human.


UBP8_HUMAN Ubiquitin carboxyl-terminal hydrolase 8 (sprot)

A ubiquitin carboxyl-terminal hydrolase 8 that is encoded in the genome of human.


UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase 15 (sprot)

A ubiquitin carboxyl-terminal hydrolase 15 that is encoded in the genome of human.


UBP3_HUMAN Ubiquitin carboxyl-terminal hydrolase 3 (sprot)

A ubiquitin carboxyl-terminal hydrolase 3 that is encoded in the genome of human.


AQP1_HUMAN Aquaporin-1 (sprot)

An aquaporin-1 that is encoded in the genome of human.


AQP4_HUMAN Aquaporin-4 (sprot)

An aquaporin-4 that is encoded in the genome of human.


AQP10_HUMAN Aquaporin-10 (sprot)

An aquaporin-10 that is encoded in the genome of human.


UBP11_HUMAN Ubiquitin carboxyl-terminal hydrolase 11 (sprot)

A ubiquitin carboxyl-terminal hydrolase 11 that is encoded in the genome of human.


UBP38_HUMAN Ubiquitin carboxyl-terminal hydrolase 38 (sprot)

A ubiquitin carboxyl-terminal hydrolase 38 that is encoded in the genome of human.


UBP21_HUMAN Ubiquitin carboxyl-terminal hydrolase 21 (sprot)

A ubiquitin carboxyl-terminal hydrolase 21 that is encoded in the genome of human.


UBP37_HUMAN Ubiquitin carboxyl-terminal hydrolase 37 (sprot)

A ubiquitin carboxyl-terminal hydrolase 37 that is encoded in the genome of human.


UBP2_HUMAN Ubiquitin carboxyl-terminal hydrolase 2 (sprot)

A ubiquitin carboxyl-terminal hydrolase 2 that is encoded in the genome of human.


UBP28_HUMAN Ubiquitin carboxyl-terminal hydrolase 28 (sprot)

A ubiquitin carboxyl-terminal hydrolase 28 that is encoded in the genome of human.


UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 (sprot)

A ubiquitin carboxyl-terminal hydrolase 20 that is encoded in the genome of human.


UBP25_HUMAN Ubiquitin carboxyl-terminal hydrolase 25 (sprot)

A ubiquitin carboxyl-terminal hydrolase 25 that is encoded in the genome of human.


HACD1_HUMAN Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 (sprot)

A very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 that is encoded in the genome of human.


HACD2_HUMAN Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (sprot)

A very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 that is encoded in the genome of human.


HACD4_HUMAN Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 (sprot)

A very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 that is encoded in the genome of human.


HPSE2_HUMAN Inactive heparanase-2 (sprot)

A heparanase-2 that is encoded in the genome of human.


HTD2_HUMAN Hydroxyacyl-thioester dehydratase type 2, mitochondrial (sprot)

A hydroxyacyl-thioester dehydratase type 2, mitochondrial that is encoded in the genome of human.


ICT1_HUMAN Large ribosomal subunit protein mL62 (sprot)

An immature colon carcinoma transcript 1 protein that is encoded in the genome of human.


PTRD1_HUMAN Putative peptidyl-tRNA hydrolase PTRHD1 (sprot)

A putative peptidyl-tRNA hydrolase PTRHD1 that is encoded in the genome of human.


Water

An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms


Oleamide

A fatty amide derived from oleic acid.


1,3,7-Trimethyluric acid

An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8, and the nitrogens at positions 1, 3, and 7 are substituted by methyl groups. It is a metabolite of caffeine.


Apigenin

A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7.  It induces autophagy in leukaemia cells.


Aminoacetone

A propanone consisting of acetone having an amino group at the 1-position.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of trans-dec-3-enoic acid.


Dimethyl Sulfoxide

A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.


A retinal having 2E,4Z,6E,8E-double bond geometry.


Imerslund-Grasbeck syndrome type 1

An autosomal recessive disorder characterized by onset of megaloblastic anemia associated with decreased serum vitamin B12 (cobalamin, Cbl) in infancy or early childhood. Low molecular weight (LMW) proteinuria is frequently present, but sometimes occurs later and is usually mild or subclinical. Patients often present with vague symptoms, including failure to thrive, loss of appetite, fatigue, lethargy, and/or recurrent infections. Some patients may present later in childhood with neurologic abnormalities related to B12 deficiency, such as sensorimotor neuropathy and/or cognitive disturbances.


CD320_HUMAN CD320 antigen (sprot)

A CD320 molecule that is encoded in the genome of human.


cob(III)alamin

A cobalamin in which the central cobalt atom has an oxidation state of +3.


2-Methylbutanoic acid

A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria.


A cholestanoyl-CoA formed by thioester linkage between 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oic acid and coenzyme A.


Phenylephrine

A member of the class of the class of phenylethanolamines that is (1R)-2-(methylamino)-1-phenylethan-1-ol carrying an additional hydroxy substituent at position 3 on the phenyl ring.


Doconexent

A docosahexaenoic acid having six cis-double bonds at positions 4, 7, 10, 13, 16 and 19.


ECH1_HUMAN Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (sprot)

A Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial that is encoded in the genome of human.


ECI1_HUMAN Enoyl-CoA delta isomerase 1, mitochondrial (sprot)

An enoyl-CoA Delta isomerase 1, mitochondrial that is encoded in the genome of human.


(Z)-7-Hexadecenoic acid

A C16 fatty acid having a (Z)-double bond at the 7-position; marker of early life stage mortality in trout and of physiologically active autotrophic bacteria in complex microbial communities.


An EET obtained by formal epoxidation of the 5,6-double bond of arachidonic acid.


Bismuth cation

A bismuth cation having a net electric charge of +3.


3-(4-Hydroxyphenyl)propionic acid

A hydroxy monocarboxylic acid consisting of propionic acid having a 4-hydroxyphenyl group at the 3-position.


DPEP2_HUMAN Dipeptidase 2 (sprot)

A dipeptidase 2 that is encoded in the genome of human.


leukotriene E4

A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and an L-cystein-S-yl group at position 6 (6R).


Arachidic Acid

A C20 striaght-chain saturated fatty acid which forms a minor constituent of peanut (L. arachis) and corn oils. Used as an organic thin film in the production of liquid crystals for a wide variety of technical applications.


4a-Carbinolamine tetrahydrobiopterin

A 6,7-dihydrobiopterin that has R configuration at position 6 and in which the 1,2-dihydroxypropyl substituent has 1R,2S configuration.


(S)-methylmalonaldehydic acid

A 2-methyl-3-oxopropanoic acid that has S-configuration.


Adrenic acid

The all-cis-isomer of a C22 polyunsaturated fatty acid having four double bonds in the 7-, 10-, 13- and 16-positions. One of the most abundant fatty acids in the early human brain.


Gondoic Acid

An icosenoic acid having a cis- double bond at position 11.


8,9-Epoxyeicosatrienoic acid

An EET obtained by formal epoxidation of the 8,9-double bond of arachidonic acid.


A 1-pyrrolinecarboxylic acid having a hydroxy substituent at the 4-position.


Picolinic acid

A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.


Lauroylcarnitine

An O-acyl-L-carnitine in which the acyl group is specified as lauroyl (dodecanoyl).


Benzoyl-coa

The simplest member of the class of  benzoyl-CoAs that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of benzoic acid.


Heptadecanoic acid

A C17 saturated fatty acid and trace component of fats in ruminants.


2-Hydroxytetradecanoic acid

A  long-chain fatty acid that is a derivative of myristic acid having a hydroxy substituent at C-2.


A DHET obtained by formal dihydroxylation across the 14,15-double bond of arachidonic acid.


Curcumin

A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa.


3-(1H-imidazol-4-yl)propanoic acid

A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 3 has been replaced by an imidazol-4-yl group.


A neopterin where positions C-7 and C-8 have been hydrogenated.


A 4a-hydroxytetrahydrobiopterin which has R configuration at position 6 and in which the dihydroxypropyl substituent has L-erythro configuration.


An N-substituted cadaverine that is cadaverine in which one of the amino groups has been converted to the corresponding acetamide.


GET3_HUMAN ATPase GET3 (sprot)

An ATPase GET3 that is encoded in the genome of human.


(R)-3-Amino-2-methylpropanoic acid

The (R)-enantiomer of 3-aminoisobutyric acid.


3-Indolepropionic acid

An  indol-3-yl carboxylic acid that is  propionic acid substituted by a 1H-indol-3-yl group at position 3.


Dimethyl sulfide

A methyl sulfide in which the sulfur atom is substituted by two methyl groups. It is produced naturally by some marine algae.


Hydrochloric Acid

A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms.


Acryloyl-CoA

The S-acryloyl derivative of coenzyme A.


A DHET obtained by formal dihydroxylation across the 8,9-double bond of arachidonic acid.


A DHET obtained by formal dihydroxylation across the 11,12-double bond of arachidonic acid.


1-Imidazolelactic acid

An imidazolyl carboxylic acid that is lactic acid in which one of the methyl hydrogens is substituted by an imidazol-1-yl group.


Cadaverine

An alkane-alpha,omega-diamine comprising a straight-chain pentane core with amino substitutents at positions 1 and 5. A colourless syrupy liquid diamine with a distinctive unpleasant odour, it is a homologue of putresceine and is formed by the bacterial decarboxylation of lysine that occurs during protein hydrolysis during putrefaction of animal tissue. It is also found in plants such as soyabean.


Coumestrol

A member of the class of coumestans that is coumestan with hydroxy substituents at positions 3 and 9.


Tridecanedioic acid

An alpha,omega-dicarboxylic acid that is undecane substituted by carboxylic acid groups at positions C-1 and C-11.


Oxalic Acid

An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2.


Biochanin A

A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at position 5 and a methoxy group at position 4'. A phytoestrogen, it has putative benefits in dietary cancer prophylaxis.


A DHET obtained by formal dihydroxylation across the 5,6-double bond of arachidonic acid.


Stearyl Alcohol

A long-chain primary fatty alcohol consisting of a hydroxy function at C-1 of an unbranched saturated chain of 18 carbon atoms.


Hawkinsin

A cysteine derivative that is cysteine in which the thiol group is substituted by a [2-(carboxymethyl)-2,5-dihydroxycyclohex-3-en-1-yl]sulfanediyl group. Hawkinsinuria is an inherited disorder which is characterized by the inability to break down the amino acid tyrosine. This results in the finding of certain metabolites in the urine, such as hawkinsin.


Hexacosanoic acid

A 26-carbon, straight-chain, saturated fatty acid.


Oleanolic Acid

A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3.


O-tiglyl-L-carnitine

An O-acyl-L-carnitine compound having trans-2-methyl-2-butenoyl (tiglyl) as the acyl substituent.


Nervonic Acid

A tetracosenoic acid having a cis-double bond at position 15.


Alitretinoin

A retinoic acid in which the exocyclic double bonds have 7E,9Z,11E,13E geometry.


Fucosterol

A 3beta-sterol consisting of stigmastan-3beta-ol with double bonds at positions 5 and 24(28). The double bond at postion 24(28) adopts a Z-configuration.


S4A11_HUMAN Solute carrier family 4 member 11 (sprot)

A solute carrier family 4 member 11 that is encoded in the genome of human.


AKAP9_HUMAN A-kinase anchor protein 9 (sprot)

An A-kinase anchor protein 9 that is encoded in the genome of human.


N-methyl-D-aspartic acid

An aspartic acid derivative having an N-methyl substituent and D-configuration.


Ursolic Acid

A pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by a beta-hydroxy group at position 3.


5-Hydroxymethyl-2-furancarboxylic acid

A member of the class of furoic acids that is 2-furoic acid substituted at position 5 by a hydroxymethyl group.


Hydroquinone

A benzenediol comprising benzene core carrying two hydroxy substituents para to each other.


4-Deoxythreonic acid

The (2S,3R)-stereoisomer of 2,3-dihydroxybutanoic acid.


Nickel (II) ion

A nickel cation in which the nickel carries a double positive charge.


3-Hydroxybenzoic acid

A monohydroxybenzoic acid that is benzoic acid substituted by a hydroxy group at position 3. It has been isolated from Taxus baccata. It is used as an intermediate in the synthesis of plasticisers, resins, pharmaceuticals, etc.


7alpha-Hydroxy-5beta-cholan-24-oic Acid

A monohydroxy-5beta-cholanic acid in which the hydroxy group is located at the 7alpha-position. A structural derivative of the bile acid, chenodeoxycholic acid.


A steroid sulfate that is the 3-O-sulfo derivative of glycochenodeoxycholic acid.


beta-Glycerophosphoric acid

A glycerol monophosphate having the phosphate group at the 2-position.


Taurolithocholic acid 3-sulfate

The steroid sulfate of taurolithocholic acid.


Sulfoglycolithocholic acid

The 3-O-sulfo derivative of glycolithocholic acid.


A dihydroxy monocarboxylic acid that is 3-hydroxypropanoic acid substituted by a 3-hydroxyphenyl group at position 3.


Isorhamnetin

A monomethoxyflavone that is quercetin in which the hydroxy group at position 3' is replaced by a methoxy group.


6-Hydroxynicotinic acid

A monohydroxypyridine that is the 6-hydroxy derivative of nicotinic acid.


Thiamine monophosphate

A thiamine phosphate that is thiamin(1+) in which the hydroxy group is replaced by a phosphate group.


Naringenin

The (S)-enantiomer of naringenin.


L-canavanine

A non-proteinogenic L-alpha-amino acid that is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. Although structurally related to L-arginine, it is non-proteinogenic.


Cyanidin

An anthocyanidin cation that is flavylium substituted at positions 3, 3', 4', 5 and 7 by hydroxy groups.


prostaglandin J2

A member of the class of prostaglandins J that consists of prosta-5,9,13-trien-1-oic acid substituted by an oxo group at position 11 and a hydroxy group at position 15 (the 5Z,13E,15S stereoisomer).


An anhydro sugar of D-glucitol.


Methane

A one-carbon compound in which the carbon is attached by single bonds to four hydrogen atoms. It is a colourless, odourless, non-toxic but flammable gas (b.p. -161degreeC).


Desmosterol

A cholestanoid that is cholesta-5,24-diene substituted by a beta-hydroxy group at position 3. It is an intermediate metabolite obtained during the synthesis of cholesterol.


Nandrolone

A 3-oxo Delta(4)-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17.


Myricetin

A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants.


Cysteic Acid

An amino sulfonic acid that is the sulfonic acid analogue of cysteine.


Androsterone sulfate

A steroid sulfate that is the 3-sulfate of androsterone.


The 13,14-dihydro derivative of 15-oxo-prostaglandin E2.


Cianidanol

The (+)-enantiomer of catechin and a polyphenolic antioxidant plant metabolite.


DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2, mitochondrial (sprot)

A dehydrogenase/reductase SDR family member 2, mitochondrial that is encoded in the genome of human.


Cortisone

A C21-steroid that is pregn-4-ene substituted by hydroxy groups at positions 17 and 21 and oxo group at positions 3, 11 and 20.


An oleoyl-sn-glycero-3-phosphocholine in which the acyl group at position 1 is (9Z)-octadecenoyl (oleoyl) and the hydroxy group at position 2 is unsubstituted.


A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens has been replaced by a 1-methyl-1H-imidazol-4-yl group.


Docosatrienoic Acid

A long-chain omega-3 fatty acid that is docosanoic acid having three double bonds located at positions 13, 16 and 19 (the (13Z,16Z,19Z-geoisomer).


Theobromine

A dimethylxanthine having the two methyl groups located at positions 3 and 7. A purine alkaloid derived from the cacao plant, it is found in chocolate, as well as in a number of other foods, and is a vasodilator, diuretic and heart stimulator.


Androsterone glucuronide

A steroid glucosiduronic acid having androsterone as the steroid component.


Testosterone sulfate

A steroid sulfate that is testosterone substituted by a sulfoxy group at position 17.


CCL2_HUMAN C-C motif chemokine 2 (sprot)

A C-C motif chemokine 2 that is encoded in the genome of human.


NALDL_HUMAN Aminopeptidase NAALADL1 (sprot)

An aminopeptidase NAALADL1 that is encoded in the genome of human.


Hexanoyl-coenzyme a

A medium-chain fatty acyl-CoA having hexanoyl as the S-acyl group.


NEU1_HUMAN Oxytocin-neurophysin 1 (sprot)

An oxytocin-neurophysin 1 that is encoded in the genome of human.


PPCE_HUMAN Prolyl endopeptidase (sprot)

A prolyl endopeptidase that is encoded in the genome of human.


MAFF_HUMAN Transcription factor MafF (sprot)

A transcription factor MafF that is encoded in the genome of human.


A0T1J2_HUMAN Oxytocin receptor (Fragment) (trembl)


Nitrate

A nitrogen oxoanion formed by loss of a proton from nitric acid. Principal species present at pH 7.3.


6-Keto-prostaglandin F1alpha

A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.


Q59FP7_HUMAN DNA (cytosine-5)-methyltransferase 1 (Fragment) (trembl)


A pyrimidine that is a derivative of cytosine, having a methyl group at the 5-position.


Ellagic Acid

An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates.


delta-Tocopherol

A tocopherol in which the chroman-6-ol core is substituted by a methyl group at position 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.


A member of the class of catechols that is benzene-1,2-diol substituted by a nitro group at position 4.It is the by-product of the hydroxylation of p-nitrophenol.


XYLITOL

A pentitol (five-carbon sugar alcohol) having meso-configuration, being derived from xylose by reduction of the carbonyl group.


Dihomo-gamma-linolenic acid

An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.


N-Acetylserine

An N-acetyl-L-amino acid in which the amino acid specified is L-serine. Metabolite observed in cancer metabolism.


Androstanolone

A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5.


1D-myo-inositol 6-phosphate

A myo-inositol monophosphate in which the phosphate group is located at position 6.


SMS_HUMAN Somatostatin (sprot)

A somatostatin that is encoded in the genome of human.


Cysteamine

An amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2.


Erythritol

The meso-diastereomer of butane-1,2,3,4-tetrol.


Lycopene

An acyclic carotene commonly obtained from tomatoes and other red fruits.


Aniline

A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens.


ERGOTHIONEINE

A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs.


Shikimic acid

A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid substituted by hydroxy groups at positions 3, 4 and 5 (the 3R,4S,5R stereoisomer). It is an intermediate metabolite in plants and microorganisms.


QUINIC ACID

The (-)-enantiomer of quinic acid.


gamma-Linolenic acid

A C18, omega-6 acid fatty acid comprising a linolenic acid having cis- double bonds at positions 6, 9 and 12.


An anthocyanidin cation consisting of benzopyrylium with hydroxy substituents at the 3-, 5- and 7-positions and a 3,4,5-trihydroxyphenyl group at the 2-position. It is a plant pigment responsible for the colours of the plants of the genera Viola and Delphinium.


leukotriene D4

A leukotriene that is (7E,9E,11Z,14Z)-icosa-7,9,11,14-tetraenoic acid substituted by a hydroxy group at position 5 (5S) and a L-cysteinylglycinyl group at position 6 (6R).


1-Methyluric acid

An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trione substituted by a methyl group at N-1. It is one of the metabolites of caffeine found in human urine.


Benzyl Alcohol

An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent.


NOXO1_HUMAN NADPH oxidase organizer 1 (sprot)

An NADPH oxidase organizer 1 that is encoded in the genome of human.


Hydrogen Peroxide

An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.


Biocytin

A  monocarboxylic acid amide that results from the formal condensation of the carboxylic acid group of biotin with the N(6)-amino group of L-lysine.


Retinoyl beta-glucuronide

A retinoid that is retinoic acid in which the carboxy proton has been replaced by a beta-D-glucuronyl residue.


N-Methylnicotinamide

A pyridinecarboxamide that is nicotinamide in which one of the amide hydrogens is substituted by a methyl group.


A butanediol in which hydroxylation is at C-2 and C-3.


Petunidin

An anthocyanidin cation that is flavylium bearing five hydroxy substituents at positions 3, 3', 4', 5 and 7 as well as a methoxy substituent at position 5'.


Prednisone Metabolism Pathway,Drug Metabolism


CYB_HUMAN Cytochrome b (sprot)

A cytochrome b that is encoded in the genome of human.


HBG1_HUMAN Hemoglobin subunit gamma-1 (sprot)

A hemoglobin subunit gamma-1 that is encoded in the genome of human.


C56D2_HUMAN Transmembrane reductase CYB561D2 (sprot)

A transmembrane reductase CYB561D2 that is encoded in the genome of human.


CY561_HUMAN Transmembrane ascorbate-dependent reductase CYB561 (sprot)

A eukaryotic cytochrome b561 that is encoded in the genome of human.


CCHL_HUMAN Holocytochrome c-type synthase (sprot)

A holocytochrome c-type synthase that is encoded in the genome of human.


CP26A_HUMAN Cytochrome P450 26A1 (sprot)

A cytochrome P450 26A1 that is encoded in the genome of human.


FLVC1_HUMAN Heme transporter FLVCR1 (sprot)

A feline leukemia virus subgroup C receptor-related protein 1 that is encoded in the genome of human.


HRG_HUMAN Histidine-rich glycoprotein (sprot)

A histidine-rich glycoprotein that is encoded in the genome of human.


CYB5_HUMAN Cytochrome b5 (sprot)

A cytochrome b5 that is encoded in the genome of human.


ABCB6_HUMAN ATP-binding cassette sub-family B member 6 (sprot)

An ATP-binding cassette sub-family B member 6 that is encoded in the genome of human.


ABCBA_HUMAN ATP-binding cassette sub-family B member 10, mitochondrial (sprot)

An ATP-binding cassette sub-family B member 10, mitochondrial that is encoded in the genome of human.


C27C1_HUMAN Cytochrome P450 27C1 (sprot)

A cytochrome P450 27C1 that is encoded in the genome of human.


C56D1_HUMAN Probable transmembrane reductase CYB561D1 (sprot)

A probable transmembrane reductase CYB561D1 that is encoded in the genome of human.


CB5D1_HUMAN Cytochrome b5 domain-containing protein 1 (sprot)

A cytochrome b5 domain-containing protein 1 that is encoded in the genome of human.


NEUFC_HUMAN Neuferricin (sprot)

A neuferricin that is encoded in the genome of human.


CDC37_HUMAN Hsp90 co-chaperone Cdc37 (sprot)

An Hsp90 co-chaperone Cdc37 that is encoded in the genome of human.


CP26B_HUMAN Cytochrome P450 26B1 (sprot)

A cytochrome P450 26B1 that is encoded in the genome of human.


CP26C_HUMAN Cytochrome P450 26C1 (sprot)

A cytochrome P450 26C1 that is encoded in the genome of human.


CP2W1_HUMAN Cytochrome P450 2W1 (sprot)

A cytochrome P450 2W1 that is encoded in the genome of human.


CP4V2_HUMAN Cytochrome P450 4V2 (sprot)

A cytochrome P450 4V2 that is encoded in the genome of human.


FS2P1_HUMAN Putative fatty acid desaturase 2-like protein FADS2B (sprot)


FADS3_HUMAN Fatty acid desaturase 3 (sprot)

A fatty acid desaturase 3 that is encoded in the genome of human.


FRRS1_HUMAN Ferric-chelate reductase 1 (sprot)

A ferric-chelate reductase 1 that is encoded in the genome of human.


HBAT_HUMAN Hemoglobin subunit theta-1 (sprot)

A hemoglobin subunit theta-1 that is encoded in the genome of human.


HBAZ_HUMAN Hemoglobin subunit zeta (sprot)

A hemoglobin subunit zeta that is encoded in the genome of human.


HBE_HUMAN Hemoglobin subunit epsilon (sprot)

A hemoglobin subunit epsilon that is encoded in the genome of human.


HBM_HUMAN Hemoglobin subunit mu (sprot)

A hemoglobin subunit mu that is encoded in the genome of human.


HEBP1_HUMAN Heme-binding protein 1 (sprot)

A heme-binding protein 1 that is encoded in the genome of human.


HEBP2_HUMAN Heme-binding protein 2 (sprot)

A heme-binding protein 2 that is encoded in the genome of human.


HRG1_HUMAN Heme transporter HRG1 (sprot)

A heme transporter HRG1 that is encoded in the genome of human.


NF2L1_HUMAN Endoplasmic reticulum membrane sensor NFE2L1 (sprot)

An endoplasmic reticulum membrane sensor NFE2L1 that is encoded in the genome of human.


FERROHEME

A heme is any tetrapyrrolic chelate of iron.


melanoma, cutaneous malignant, susceptibility to, 1


An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4.


Testosterone glucuronide

A steroid glucosiduronic that is testosterone carrying a glucosiduronic acid residue at position 17.


Thromboxane

A class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.


Raffinose

A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively.


Genistein

A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.


Palmitoleic Acid

A hexadec-9-enoic acid in which the double bond at position C-9 has cis configuration.


trans-Vaccenic acid

The trans- isomer of vaccenic acid.


Acetoin

A methyl ketone that is butan-2-one substituted by a hydroxy group at position 3.


Rutin

A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups.


thromboxane B2

A member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.


Dihydrocortisol

A 17alpha-hydroxy-C21-steroid that is cortisol in which the 4-5 double bond has undergone formal hydrogenation to give the corresponding 5beta- steroid.


Pelargonidin

An anthocyanidin cation that is flavylium substituted by a hydroxy groups at positions 3, 5, 7 and 4'.


Nicotinuric acid

An N-acylglycine having nicotinoyl as the acyl substituent.