RREB1_HUMAN Ras-responsive element-binding protein 1 (sprot)

A Ras-responsive element-binding protein 1 that is encoded in the genome of human.


ZNF43_HUMAN Zinc finger protein 43 (sprot)

A zinc finger protein 43 that is encoded in the genome of human.


TRPS1_HUMAN Zinc finger transcription factor Trps1 (sprot)

A zinc finger transcription factor Trps1 that is encoded in the genome of human.


ZN75D_HUMAN Zinc finger protein 75D (sprot)

A zinc finger protein 75D that is encoded in the genome of human.


ZNT5_HUMAN Proton-coupled zinc antiporter SLC30A5 (sprot)

A proton-coupled zinc antiporter SLC30A5 that is encoded in the genome of human.


ZIC3_HUMAN Zinc finger protein ZIC 3 (sprot)

A zinc finger protein ZIC 3 that is encoded in the genome of human.


ZN33B_HUMAN Zinc finger protein 33B (sprot)

A zinc finger protein 33B that is encoded in the genome of human.


CHAP1_HUMAN Chromosome alignment-maintaining phosphoprotein 1 (sprot)

A zinc finger protein 828 that is encoded in the genome of human.


ZF64B_HUMAN Zinc finger protein 64 (sprot)

A zinc finger protein 64 that is encoded in the genome of human.


CPN2_HUMAN Carboxypeptidase N subunit 2 (sprot)

A carboxypeptidase N subunit 2 that is encoded in the genome of human.


Cinolazepam

A 1,4-benzodiazepinone compound having a 2-cyanoethyl substituent at the 1-position, a hydroxy substituent at the 3-position, a 2-fluorophenyl group at the 5-position and a chloro substituent at the 7-position, it has general properties similar to those of diazepam and has been used for the short-term management of sleep disorders.


Nitrazepam

A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome).


Cilastatin

The thioether resulting from the formal oxidative coupling of the thiol group of L-cysteine with the 7-position of (2Z)-2-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hept-2-enoic acid. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin is therefore administered (as the sodium salt) with  imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to inactive and potentially nephrotoxic products. Cilastatin also acts as a leukotriene D4 dipeptidase inhibitor, preventing the metabolism of leukotriene D4 to leukotriene E4.


Probucol

A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high levels of cholesterol in blood.


Tiaprofenic acid

An aromatic ketone that is thiophene substituted at C-2 by benzoyl and at C-4 by a 1-carboxyethyl group.


Lopinavir

A dicarboxylic acid diamide that is amphetamine is substituted on nitrogen by a (2,6-dimethylphenoxy)acetyl group and on the carbon alpha- to nitrogen by a (1S,3S)-1-hydroxy-3-{[(2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1-yl)butanoyl]amino}-4-phenylbutyl group. An antiretroviral of the protease inhibitor class, it is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir.


Periciazine

A member of the class of  phenothiazines that is 10H-phenothiazine substituted by a 3-(4-hydroxypiperidin-1-yl)propyl group at the nitrogen atom and a carbonitrile group at position 2. Periciazine is a first generation antipsychotic.


Deferasirox

A member of the class of triazoles, deferasirox is 1,2,4-triazole substituted by a 4-carboxyphenyl group at position 1 and by 2-hydroxyphenyl groups at positions 3 and 5. An orally active iron chelator, it is used to manage chronic iron overload in patients receiving long-term blood transfusions.


Hydroxychloroquine

An aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.


Amyl nitrite

A nitrite ester having n-pentyl as the alkyl group.


Erythrityl tetranitrate

Erythritol in which each of the hydroxy groups has been converted to the corresponding nitrate ester. It is a vasodilator with properties similar to nitroglycerin. It is usually used diluted with lactose or other suitable inert excipients, in order to minimise the risk of explosion; undiluted erythrityl tetranitrate can be exploded by percussion or excessive heat.


Acepromazine

A member of the class of  phenothiazines that is 10H-phenothiazine substituted by an acetyl group at position 2 and a 3-(dimethylamino)propyl group at position 10.


Aceprometazine

A phenothiazine compound having an acetyl group at the 2-position and a 2-(dimethylamino)-1-propyl group at the 10-position.


Alverine

A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel syndrome.


Thioproperazine

A phenothiazine derivative in which the phenothiazine tricycle has a dimethylaminosulfonyl substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at N-10.


Zuclopenthixol

The (Z)-isomer of clopenthixol.


Etoricoxib

A member of the class of bipyridines that is 2,3'-bipyridine which is substituted at the 3, 5, and 6' positions by 4-(methylsulfonyl)phenyl, chlorine, and methyl groups, respectively.


Calcipotriol

A seco-cholestane that is 26,27-cyclo-9,10-secocholesta-5,7,10,22-tetraene carrying additional hydroxy substituents at positions 1, 3 and 24. It is used (as its hydrate) in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients.


Vorinostat

A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and  hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).


Fusidic Acid

A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum.


FSHR_HUMAN Follicle-stimulating hormone receptor (sprot)

A follitropin receptor that is encoded in the genome of human.


Suramin

A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.


Bifonazole

A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.


Chlophedianol

A diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain.


Cyclandelate

The ester obtained by formal condensation of mandelic acid and 3,3,5-tricyclohexanol. It is a direct-acting smooth muscle relaxant used to dilate blood vessels.


Tetrabenazine

A benzoquinolizine that is 1,2,3,4,4a,9,10,10a-octahydrophenanthrene in which the carbon at position 10a is replaced by a nitrogen and which is substituted by an isobutyl group at position 2, an oxo group at position 3, and methoxy groups at positions 6 and 7.


Nebivolol

A member of the class of chromanes that is 2,2'-iminodiethanol in which one hydrogen attached to each hydroxy-bearing carbon is replaced by a  6-fluorochroman-2-yl group.


Nilotinib Inhibition of BCR-ABL,Drug Action

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Ximelagatran

A member of the class of azetidines that is melagatran in which the carboxylic acid group has been converted to the corresponding ethyl ester and in which the amidine group has been converted into the corresponding amidoxime. A prodrug for melagatran, ximelagatran was the first orally available direct thrombin inhibitor to be brought to market as an anticoagulant, but was withdrawn in 2006 following reports of it causing liver damage.


Permethrin

A cyclopropanecarboxylate ester in which the esterifying alcohol is 3-phenoxybenzyl alcohol and the cyclopropane ring is substituted with a 2,2-dichlorovinyl group and with gem-dimethyl groups.


Tamibarotene

A dicarboxylic acid monoamide resulting from the condensation of one of the carboxy groups of terephthalic acid with the amino group of 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine.


Lucanthone

A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.


Indacaterol

A monohydroxyquinoline that consists of 5-[(1R)-2-amino-1-hydroxyethyl]-8-hydroxyquinolin-2-one having a 5,6-diethylindan-2-yl group attached to the amino function. Used as the maleate salt for treatment of chronic obstructive pulmonary disease.


Trabectedin

A tetrahydroisoquinoline alkaloid obtained from a Caribbean tunicate Ecteinascidia turbinata. Used for the treatment of soft tissue sarcoma and relapsed ovarian cancer.


Telaprevir

An oligopeptide consisting of N-(pyrazin-2-ylcarbonyl)cyclohexylalanyl, 3-methylvalyl, octahydrocyclopenta[c]pyrrole-1-carboxy, and 3-amino-N-cyclopropyl-2-oxohexanamide residues joined in sequence. Used for treatment of chronic hepatitis C virus genotype 1 infection.


Sertindole

A phenylindole that is 1H-indole which is substituted on the nitrogen by a p-chlorophenyl group, at position 5 by chlorine, and at position 3 by a piperidin-4-yl group, which is itself substituted on the nitrogen by a 2-(2-oxoimidazolidin-1-yl)ethyl group.


Sulfathiazole

A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position.


Mianserin

A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.


Sulfadimethoxine

A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.


Rimonabant

A carbohydrazide obtained by formal condensation of the carboxy group of 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic acid with the amino group of 1-aminopiperidine. It is a potent and selective cannabinoid receptor 1 (CB1R) antagonist. Besides its antagonistic properties, numerous studies have shown that, at micromolar concentrations rimonabant behaves as an inverse agonist at CB1 receptors. The drug was the first selective CB1 antagonist/inverse agonist introduced into clinical practice to treat obesity and metabolic-related disorders. It was later withdrawn from market due to CNS-related adverse effects including depression and suicidal ideation.


Amisulpride

A member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D2 and D3 receptor antagonist. It is an atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects.


Saxagliptin

A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2S)-amino(3-hydroxyadamantan-1-yl)acetic acid with the amino group of (1S,3S,5S)-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Used in its monohydrate form for the treatment of Type II diabetes.


Vilazodone

A 1-benzofuran that is 5-(piperazin-1-yl}-1-benzofuran-2-carboxamide having a (5-cyanoindol-3-yl)butyl group attached at position N-4 on the piperazine ring. Used for the treatment of major depressive disorder.


Mepyramine

An ethylenediamine derivative that is  ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.


Dabigatran etexilate

An aromatic amide obtained by formal condensation of the carboxy group of 2-{[(4-{N'-[(hexyloxy)carbonyl]carbamimidoyl}phenyl)amino]methyl}-1-methyl-1H-benzimidazole-5-carboxylic acid with the secondary amino group of ethyl N-pyridin-2-yl-beta-alaninate. A prodrug for dabigatran, a thrombin inhibitor and anticoagulant which is used for the prevention of stroke and systemic embolism.


Arbekacin

A kanamycin that is kanamycin B bearing an N-(2S)-4-amino-2-hydroxybutyryl group on the aminocyclitol ring.


Artemether

An artemisinin derivative that is artemisinin in which the lactone has been converted to the corresponding lactol methyl ether. It is used in combination with lumefantrine as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria.


Betahistine

An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease.


Desvenlafaxine

A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-hydroxyphenyl group. It is a metabolite of the drug venlafaxine.


Dexmethylphenidate

A methyl phenyl(piperidin-2-yl)acetate in which both stereocentres have R configuration.  It is the active enantiomer in the racemic drug methylphenidate.


Levonordefrin

A catecholamine in which the 2-aminoethyl group is substituted with a hydroxy group at C-1 and a methyl group at C-2, with configurations 1R,2S. A metabolite of alpha-methyl-L-dopa, it is an alpha2-adrenergic agonist and acts as a topical nasal decongestant and vasoconstrictor, most often used in dentistry.


Lumefantrine

A member of the class of fluorenes that is 9-(p-chlorobenzylidene)-9H-fluorene which is substitutec by chlorine at positions 2 and 7, and by a 2-(dibutylamino)-1-hydroxyethyl group at position 4. An antimalarial drug used in combination with artemether for the treatment of multi-drug resistant strains of falciparum malaria.


Methacholine

A quaternary ammonium ion in which the nitrogen is substituted with three methyl groups and a 2-acetoxypropyl group. Parasympathomimetic bronchoconstrictor drug used in clinical diagnosis.


Methyltestosterone

A 17beta-hydroxy steroid that is testosterone bearing a methyl group at the 17alpha position.


Fosaprepitant

A morpholine derivative that is the (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl ether of (3-{[(2R,3S)-3-(4-fluorophenyl)-2-hydroxymorpholin-4-yl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid.


Sulfaphenazole

A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.


Alcaftadine

An imidazobenzazepine that is 6,11-dihydro-5H-imidazo[2,1-b][3]benzazepine substituted at position 3 by a formyl group and at position 11 by a 1-methylpiperidin-4-ylidene group. An antihistamine used for treatment of allergic conjunctivitis.


Cabazitaxel

A tetracyclic diterpenoid that is 10-deacetylbaccatin III having O-methyl groups attached at positions 7 and 10 as well as an O-(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl group attached at position 13. Acts as a microtubule inhibitor, binds tubulin and promotes microtubule assembly and simultaneously inhibits disassembly.


Carglumic acid

A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia.


Nepafenac

A monocarboxylic acid amide that is amfenac in which the carboxylic acid group has been converted into the corresponding carboxamide. It is a prodrug for amfenac, used in eye drops to treat pain and inflammation following cataract surgery.


Niclosamide

A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.


Nonaethylene glycol nonylphenyl ether

A tergitol polymer consisting of nonylbenzene with a nine-membered poly(ethylene glycol) moiety attached at position 4.


Plerixafor

An azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma.


Sulfamoxole

A sulfonamide antibiotic in which 4-aminobenzenesulfonic acid and 4,5-dimethyl-1,3-oxazol-2-amine have combined to form the sulfonamide bond.


Antazoline

A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.


Bopindolol

A methylindole that is 2-methyl-1H-indol-4-ol in which the hydrogen of the hydroxy group is replaced by a 2-(benzoyloxy)-3-(tert-butylamino)propyl group.


Ticagrelor

A triazolopyrimidine that is an adenosine isostere; the cyclopentane ring is similar to ribose and the nitrogen-rich [1,2,3]triazolo[4,5-d]pyrimidine moiety resembles the nucleobase adenine. A platelet aggregation inhibitor which is used for prevention of thromboembolic events in patients with acute coronary syndrome.


Ivacaftor

An aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis.


Alanine glutamate

A dipeptide consisting of L-glutamic acid having an L-alanyl attached to its alpha-amino group


Ala-ile

A dipeptide formed from L-alanyl and L-isoleucine residues.


Alanylphenylalanine

A dipeptide formed from L-alanyl and L-phenylalanine residues.


Ala-Tyr

A dipeptide composed of L-alanine and L-tyrosine joined by a peptide linkage.


Arginylisoleucine

A dipeptide formed from L-arginyl and L-isoleucine residues.


Arginyl-Leucine

A dipeptide formed from L-arginyl and L-leucine residues.


Arginyl-Methionine

A dipeptide formed from L-arginine and L-methionine residues.


Arginylphenylalanine

A dipeptide formed from L-arginine and L-phenylalanine residues. It exhibits vasorelaxant activity.


Arginylproline

A dipeptide obtained by formal condensation of the carboxy group of L-arginine with the amino group of L-proline.


Arg-Tyr

A dipeptide formed from L-arginine and L-tyrosine residues.


Arginyl-Valine

A dipeptide formed from L-arginine and L-valine residues.


Asparaginyl-Isoleucine

A dipeptide obtained by formal condensation of the carboxy group of L-asparagine with the amino group of L-isoleucine.


Gln-Gln

A dipeptide formed from two L-glutamine residues.


Glutamylisoleucine

A dipeptide obtained by formal condensation of the carboxy group of L-glutamic acid with the amino group of L-isoleucine.


Glu-Leu

A dipeptide composed of L-glutamic acid and L-leucine joined by a peptide linkage.


Oglufanide

A dipeptide composed of L-glutamic acid and L-tryptophan joined by a peptide linkage.


Glu-Tyr

A dipeptide composed of L-glutamic acid and L-tyrosine joined by a peptide linkage.


Glutamyl-Valine

A glutamyl-L-amino acid that is the N-(L-alpha-glutamyl) derivative of L-leucine.


Glycyl-L-tyrosine

A dipeptide composed of glycine and L-tyrosine joined by a peptide linkage.


Glycyl-L-valine

A dipeptide formed from glycine and L-valine residues.


Histidylglycine

A dipeptide formed from L-histidine and glycine residues.


Histidylisoleucine

A dipeptide obtained by formal condensation of the carboxy group of L-histidine with the amino group of L-isoleucine.


Histidylphenylalanine

A dipeptide obtained by formal condensation of the carboxy group of L-histidine with the amino group of L-phenylalanine.


His-Trp

A dipeptide formed from L-histidine and L-tryptophan residues.


His-Val

A dipeptide formed from L-histidine and L-valine residues.


L-Leucyl-L-alanine

A dipeptide composed of L-leucine and L-alanine joined by a peptide linkage.


Lysyl-Isoleucine

A dipeptide formed from L-lysine and L-isoleucine residues.


Lys-Leu

A dipeptide formed from L-lysine and L-leucine residues.


Lysylphenylalanine

A dipeptide formed from L-lysine and L-phenylalanine residues.


Lysylproline

A dipeptide formed from L-lysine and L-proline residues.


Lys-Tyr

A dipeptide formed from L-lysine and L-tyrosine residues.


Lysylvaline

A dipeptide formed from L-lysine and L-valine residues.


Phe-Asp

A dipeptide formed from L-phenylalanine and L-aspartic acid residues.


Phenylalanylglutamate

A dipeptide formed from L-phenylalanine and L-glutamic acid residues.


Phe-gly

A dipeptide formed from L-phenylalanine and glycine residues.


Phe-Ile

A dipeptide formed from L-phenylalanine and L-isoleucine residues.


Phenylalanylserine

A dipeptide that is the N-(L-phenylalanyl) derivative of L-serine.


Phenylalanyltryptophan

A dipeptide formed from L-phenylalanine and L-tryptophan residues.


Phenylalanyltyrosine

A dipeptide formed from L-phenylalanine and L-tyrosine residues.


Phe-Val

A dipeptide formed from L-phenylalanine and L-valine residues.


Ser-Ile

A dipeptide obtained by formal condensation of the carboxy group of L-serine with the amino group of L-isoleucine.


Ser-Leu

A dipeptide formed from L-serine and L-leucine residues.


Ser-phe

A dipeptide that is the N-(L-seryl) derivative of L-phenylalanine.


Ser-Pro

A dipeptide formed from L-serine and L-proline residues.


Ser-Val

A dipeptide formed from L-serine and L-valine residues.


Threonylisoleucine

A dipeptide obtained by formal condensation of the carboxy group of L-threonine with the amino group of L-isoleucine.


Thr-Leu

A dipeptide formed from L-threonine and L-leucine residues.


Threonylphenylalanine

A dipeptide formed from L-threonine and L-phenylalanine residues.


Threonyl-valine

A dipeptide obtained by formal condensation of the carboxy group of L-threonine with the amino group of L-valine.


Tyrosyl-Tyrosine

A dipeptide comprising tyrosine with a tyrosyl residue attached to the alpha-nitrogen.


Valylalanine

A dipeptide formed from L-valine and L-alanine residues.


Val-Arg

A dipeptide formed from L-valine and L-asparagine residues.


Val-Asp

A dipeptide formed from L-valine and L-aspartic acid residues.


Valylglutamine

A dipeptide formed from L-valine and L-glutamine residues.


Valylglutamic acid

A dipeptide formed from L-valine and L-glutamic acid residues.


Valylhistidine

A dipeptide formed from L-valine and L-histidine residues.


Val-Ile

A dipeptide formed from L-valine and L-isoleucine residues.


Valylleucine

A dipeptide formed from L-valine and L-leucine residues.


Valyllysine

A dipeptide formed from L-valine and L-lysine residues.


Valyl-Methionine

A dipeptide formed from L-valine and L-methionine residues.


L-valyl-L-phenylalanine

A dipeptide formed from L-valine and L-phenylalanine residues.


Val-ser

A dipeptide formed from L-valine and L-serine residues.


Val-Tyr

A dipeptide formed from L-valine and L-tyrosine residues.


Val-val

A dipeptide formed from two L-valine residues.


A member of the class of  phenols carrying an ethyl substituent at position 4.


Piperine

A N-acylpiperidine that is piperidine substituted by a (1E,3E)-1-(1,3-benzodioxol-5-yl)-5-oxopenta-1,3-dien-5-yl group at the nitrogen atom. It is an alkaloid isolated from the plant Piper nigrum.


Galangin

A 7-hydroxyflavonol with additional hydroxy groups at positions 3 and 5 respectively; a growth inhibitor of breast tumor cells.


Trichloroethylene

A member of the class of  chloroethenes that is ethene substituted by chloro groups at positions 1, 1 and 2.


Nonane

A straight chain alkane composed of 9 carbon atoms.


Chloroform

A one-carbon compound that is methane in which three of the hydrogens are replaced by chlorines.


Cyclohexane

An alicyclic hydrocarbon comprising a ring of six carbon atoms; the cyclic form of hexane, used as a raw material in the manufacture of nylon.


n-HEXANE

An unbranched alkane containing six carbon atoms.


Pentane

A straight chain alkane consisting of 5 carbon atoms.


Tricetin

Flavone hydroxylated at positions 3', 4', 5, 5' and 7.


Naringenin chalcone

A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 2' ,4, 4', and 6' respectively.


Diosmetin

A monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities.


Cinnamyl alcohol

The E (trans) stereoisomer of cinnamyl alcohol.


Thiophene

Compounds containing at least one thiophene ring.


Saccharin

A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.


A member of the class of furans that is furan in which the hydrogens at positions 2 and 5 are replaced by ethyl and methyl groups, respectively.


Naphthalene

An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia.


Danthron

A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 8.


Umbelliferone

A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7.


d-Tartaric acid

The D-enantiomer of tartaric acid.


beta-D-Arabinopyranose

A D-arabinopyranose with beta-configuration at the anomeric position.


Methyl beta-D-glucopyranoside

A beta-D-glucopyranoside having a methyl substituent at the anomeric position.


Hexyl acetate

The acetate ester of  hexan-1-ol.


Menatetrenone

A menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration.


Ethyl isovalerate

The fatty acid ethyl ester of isovaleric acid.


Butyl propionate

A propanoate ester of butan-1-ol.


Ethyl propionate

A propanoate ester of ethanol.


Propyl propionate

A propanoate ester resulting from the formal condensation of the hydroxy group of propanol with the carboxy group of propanoic acid.


An  ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.


Arecoline

A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.


DL-Tryptophan

An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3.


Sterigmatocystin 50 microg/mL in Acetonitrile


Chryseriol

The 3'-O-methyl derivative of luteolin.


Kuromanin

An anthocyanin cation that is a cyanidin cation linked to a beta-D-glucosyl moiety at position 3.


Cyclomorusin

An extended flavonoid that is cyclomulberrin in which the hydroxy group at position 10 has undergone oxidative cyclisation to position 3 of the 3-methylbut-2-en-1-yl substituent, with migration of the double bond into conjugation with the aromatic ring. It is a moderate inhibitor of acetylcholinesterase (IC50 = 16.2 - 36.6 muM), and a  strong inhibitor of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) induced platelet aggregation.


Cyclomulberrin

A extended flavonoid that is 6H,7H-chromeno[4,3-b]chromen-7-one which is substituted by a 2-methylprop-1-en-1-yl group at position 6, a 3-methylbut-2-en-1-yl group at position 11, and hydroxy groups at positions 3, 8, and 10. It is found in the bark of Morus species and has been reported to protect human neuronal cells derived from the human neuroblastoma SH-SY5Y cell line.


Demethoxyegonol

A member of the class of 1-benzofurans that is  egonol in which the methoxy group at position 7 is replaced by a hydrogen. It has been isolated from the fruits of Styrax agrestis.


Morin

A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.


Myricanone

A cyclic ketone isolated from the bark of Morella species and has been shown to exhibit cytotoxic activity against cancer cells.


Patuletin

A trimethoxyflavone that is quercetagetin methylated at position 6.


Pedalitin

A tetrahydroxy-monohydroxy-flavone, with the four hydroxy groups at C-3',-4',-5 and 6, and the methoxy group at C-7.  It has been isolated from a number of plant species, including Eremosparton songoricum, Rabdosia japonica and Ruellia tuberosa.


Pinocembrin

A dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea.


Esculetin

A  hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light.


Esculin

A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.


Alternariol

A benzochromenone that is 6H-benzo[c]chromen-6-one which is substituted by a methyl group at position 1 and by hydroxy groups at positions 3, 7, and 9. It is the most important mycotoxin produced by the black mould Alternaria species, which are the most common mycoflora infecting small grain cereals worldwide.


Amentoflavone

A biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-8 of the chromene ring.  A natural product found  particularly in Ginkgo biloba and Hypericum perforatum.


A hexahydroxyflavanone that is the 2,3-dihydro derivative of myricetin.


Trifolin

A beta-D-galactoside compound with a 4',5,7-trihydroxychromen-3-yl group at the anomeric position.


2-Octenal, (2Z)-

The (Z)-isomer of oct-2-enal.


2S-hydroxyhexadecanoic acid

The S-enantiomer of 2-hydroxypalmitic acid.


14-Methylpentadecanoic acid

A methyl-branched fatty acid that is pentadecanoic acid substituted by a methyl group at position 14. It is a biomarker for rheumatoid arthritis.


12-Methyltridecanoic acid

A branched-chain saturated fatty acid consisting of tridecanoic acid carrying a 12-methyl group.


Pentadecanal

A long-chain fatty aldehyde that is pentadecane carrying an oxo substituent at position 1. It is a component of essential oils from plants like Solanum erianthum and Cassia siamea.


Tetrahydrofurfuryl alcohol

A primary alcohol that is methanol in which one of the hydrogens of the methyl group has been replaced by a tetrahydrofuran-2-yl group.


Tricarballylic acid

A tricarboxylic acid that is glutaric acid in which one of the beta-hydrogens is substituted by a carboxy group.


Valeraldehyde

A saturated fatty aldehyde composed from five carbons in a straight chain.


A  hydroxyether that is the  ethyl ether derivative of ethylene glycol.


Ethyl Acetate

The acetate ester formed between acetic acid and ethanol.


Urethane

A carbamate ester obtained by the formal condensation of ethanol with carbamic acid. It has been found in alcoholic beverages.


A primary alcohol that is hexan-1-ol substituted by an ethyl group at position 2.


Isobutyraldehyde

A member of the class of propanals that is propanal substituted by a methyl group at position 2.


Ethyl isobutyrate

A fatty acid methyl ester obtained by the formal condensation of isobutyric acid with ethanol.


A methyl ketone that is nonane in which the methylene hydrogens at position 2 are replaced by an oxo group.


A methyl ketone that is octane substituted by an oxo group at position 2.


A dialkyl ketone that is octane in which the two methylene protons at position 3 have been replaced by an oxo group.


An alkenyl alcohol with a structure based on a C8 unbranched chain with the hydroxy group at C-2 and unsaturation at C-1-C-2. It is a major volatile compound present in many mushrooms and fungi.


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Butyl acetate

The acetate ester of butanol.


Chloroacetic acid

A chlorocarboxylic acid that is acetic acid carrying a 2-chloro substituent.


Methyl cyclohexanecarboxylate

A methyl ester resulting from the formal condensation of the carboxy group of cyclohexanecarboxylic acid with methanol.


Cyclohexylamine

A primary aliphatic amine consisting of cyclohexane carrying an amino substituent.


A methyl ketone that is decane in which the methylene hydrogens at position 2 are replaced by an oxo group.


Dodecane

A straight-chain alkane with 12 carbon atoms. It has been isolated from the essential oils of various plants including Zingiber officinale (ginger).


Undecane

A straight-chain alkane with 11 carbon atoms.


Decane

A straight-chain alkane with 10 carbon atoms.


tert-Butanol

A tertiary alcohol alcohol that is isobutane substituted by a hydroxy group at position 2.


Heptanal

An n-alkanal resulting from the oxidation of the alcoholic hydroxy group of heptan-1-ol to the corresponding aldehyde. An endogenous aldehyde coming from membrane lipid oxidation, it is found in the blood of lung cancer patients and has been regarded as a potential biomarker of lung cancer.


A primary alcohol that is heptane substituted by a hydroxy group at position 1. It has been isolated from Capillipedium parviflorum.


A primary alpha-hydroxy ketone that is butane-1,2-diol in which the hydroxy group at position 2 has been formally oxidised to give the corresponding ketone.


D-malate

An optically active form of malic acid having (R)-configuration.


Methyl acetate

An acetate ester resulting from the formal condensation of acetic acid with methanol. A low-boiling (57 degreeC) colourless, flammable liquid, it is used as a solvent for many resins and oils.


Bromomethane

A one-carbon compound in which the carbon is attached by single bonds to three hydrogen atoms and one bromine atom. It is produced naturally by marine algae.


A 2-methylbutanal that has S configuration.


A methylbutanal in which the methyl substituent is at position 2.


Isoamyl acetate

The acetate ester of isoamylol.


2-Methylvaleric acid

A methyl-branched fatty acid that is pentanoic acid which carries a methyl group at position 2.


An alpha-diketone that is pentane substituted at the 2- and 3-positions by oxo groups.


4-Pentenoic acid

A pentenoic acid having the double bond at position 4.


Phenoxyacetic acid

A monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes.


Acrylic acid

A alpha,beta-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group.


Allyl alcohol

A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds.


3-Aminobutanoic acid

A beta-amino acid that is butyric acid which is substituted by an amino group at position 3.


Ferreirin

A hydroxyisoflavanone that is isoflavanone substituted by hydroxy groups at positions 5, 7 and 2' and a methoxy group at position 4' respectively.


A monohydroxyflavone that is the 3-hydroxy derivative of flavone.


Phenyl salicylate

A benzoate ester that is the phenyl ester of salicylic acid. Also known as salol, it can be formed by heating salicylic acid with phenol and is used in the manufacture of some polymers, lacquers, adhesives, waxes and polishes.


Resorcinol

A  benzenediol that is benzene dihydroxylated at positions 1 and 3.


Benzoin

A ketone that consists of acetophenone bearing hydroxy and phenyl substituents at the alpha-position. The parent of the class of benzoins.


N-Acetyl-L-histidine

A  histidine derivative that is L-histidine having an acetyl substituent on the alpha-nitrogen.


A member of the class of phenols that is phenol substituted with a  tert-butyl group at position 4.


Cellulose gel

A (1->4)-beta-D-glucan (cellulose) in crystalline form with a structure consisting of several hundred to over ten thousand D-glucose residues joined by beta(1->4) glycosidic linkages.


Deanol

A  tertiary amine that is ethanolamine having two N-methyl substituents.


Triethanolamine

A tertiary amino compound that is ammonia in which each of the hydrogens is substituted by a 2-hydroxyethyl group.


Methylparaben

A 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries.


Propylparaben

The benzoate ester that is the propyl ester of 4-hydroxybenzoic acid.   Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive.


Zingerone

A methyl ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger.


2-Methoxybenzoic acid

A  methoxybenzoic acid that is the methyl ether of salicylic acid.


3-Methoxybenzoic acid

A methoxybenzoic acid that is benzoic acid substituted by a methoxy group at position 3.


Piperonylic acid

A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties.


Sinapinic acid

A sinapic acid in which the double bond has trans-configuration.


An aromatic alcohol that is ethanol substituted by a phenyl group at position 1.


Furfural

An aldehyde that is furan with the hydrogen at position 2 substituted by a formyl group.


A thiophene that is substituted by methyl groups at positions 3 and 4.


A 1,3-thiazole that is thiazole substituted by a methyl group at position 4 and a 2-hydroxyethyl group at position 5.


4-Methylumbelliferyl acetate

An acetate ester consiting of umbelliferone carrying a 7-O-acetyl group.


The (R,R) diastereoisomer of butane-2,3-diol.


A 1,3-thiazole substituted by a methyl group at position 4.


A member of the class of furans that is furan in which the hydrogens at positions 2 and 5 are replaced by methyl groups.


Dimethyl selenide

An organoselenium compound of two methyl groups covalently bound to a selenium.


Mollicellin C

A member of the class of depsidones that is 11H-dibenzo[b,e][1,4]dioxepine substituted by hydroxy groups at positions 3 and 9, a methoxy group at position 8, methyl groups at positions 1 and 6, a 3-methylbut-2-enoyl group at position 7, an oxo group at position 11 and a formyl group at position 4. Isolated from Chaetomium brasiliense, it exhibits antimalarial and cytotoxic activities.


Mollicellin E

A member of the class of depsidones that is 11H-dibenzo[b,e][1,4]dioxepine substituted by a chloro group at position 2,  hydroxy groups at positions 3 and 9, a methoxy group at position 8, methyl groups at positions 1 and 6, a 3-methylbut-2-enoyl group at position 7, an oxo group at position 11 and a formyl group at position 4. Isolated from Chaetomium brasiliense, it exhibits antimalarial and cytotoxic activities.


mollicellin H

A member of the class of  depsidones that is 11H-dibenzo[b,e][1,4]dioxepine substituted by hydroxy groups at position 3 and 7, methyl group at positions 1 and 9, a prenyl group at position 8, an oxo group at position 11 and a formyl group at position 4. Isolated from  Chaetomium brasiliense it exhibits cytotoxic activity.


Hexyl butyrate

A fatty acid ester obtained by the formal condensation of hexanol with butyric acid.


A primary alcohol that is pentanol substituted by a methyl group at position 3.


A dialkyl ketone with methyl and nonyl as the two alkyl groups.


A benzene which is substituted by a 3-oxopropyl group at position 1.


A ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at position 4 by a hydroxy group. It is found in a variety of fruits including raspberries, blackberries and cranberries, and is used in perfumery and cosmetics.


(S)-2-methylbutanoic acid

The (S)-enantiomer of 2-methylbutanoic acid.


2-Hydroxybenzenepropanoic acid

A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 3 is substituted by a 2-hydroxyphenyl group.


3-Methylvaleric acid

A methyl-branched fatty acid that is pentanoic acid which carries a methyl group at position 3.


Hexadecane

A straight-chain alkane with 16 carbon atoms. It is a component of essential oil isolated from long pepper.


Cryptoxanthin

A carotenol that exhibits antioxidant activity. It has been isolated from fruits such as papaya and oranges.


Benzylamine

A primary amine compound having benzyl as the N-substituent. It has been isolated from  Moringa oleifera (horseradish tree).


Ethyl butyrate

A butyrate ester resulting from the formal condensation of the hydroxy group of ethanol with the carboxy group of butyric acid.


A secondary alcohol that is heptane substituted by a hydroxy group at position 2.


Acetophenone

A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.


A secondary alcohol that is nonane substituted by a hydroxy group at position 2.


Dodecanal

A long-chain fatty aldehyde that is dodecane in which two hydrogens attached to a terminal carbon are replaced by an oxo group.


Phenylethyl Alcohol

A primary alcohol that is ethanol substituted by a phenyl group at position 2.


Daidzin

A glycosyloxyisoflavone that is  daidzein attached to a beta-D-glucopyranosyl residue at position 7 via a glycosidic linkage. It is used in the treatment of alcohol dependency (antidipsotropic).


A hydroxyisoflavone that is genistein substituted by an additional hydroxy group at position 2'. It has been isolated from Crotalaria lachnophora.


Estragole

A phenylpropanoid that is chavicol in which the hydroxy group is replaced by a methoxy group.


Octadecanamide

A fatty amide of stearic acid.


A methyl ketone that is tridecane in which the methylene hydrogens at position 2 are replaced by an oxo group.


Isopentyl formate

The formate ester of isoamylol.


Propyl hexanoate

A hexanoate ester obtained by the formal condensation of the carboxy group of hexanoic acid (caproic acid) with  propan-1-ol.


Toluene

The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent.


PINITOL

The D-enantiomer of pinitol.


Crotonaldehyde

An enal consisting of propene having a formyl group at the 1-position.


A pentanone carrying an oxo substituent at position 2.


Propyl acetate

An  acetate ester obtained by the formal condensation of acetic acid with propanol.


Styrene

A vinylarene that is benzene carrying a vinyl group. It has been isolated from the benzoin resin produced by Styrax species.


2-Aminoheptanedioic acid

An amino dicarboxylic acid that is heptanedioic acid in which a hydrogen at position 2 is replaced by an amino group. It is a component of the cell wall peptidoglycan of bacteria.


Tetradecanal

A long-chain fatty aldehyde that is tetradecane in which two hydrogens attached to a terminal carbon are replaced by an oxo group. It is found in coriander.


Tridecane

A straight chain alkane containing 13 carbon atoms. It forms a component of the essential oils isolated from plants such as Abelmoschus esculentus.


Nonadecane

A straight-chain alkane with 19 carbon atoms. It has been found as a component of essential oils isolated from Artemisia armeniaca.


Piperidine

An azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. It is a metabolite of cadaverine, a polyamine found in the human intestine.


Scopoletin

A hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6.


gamma-Glutamylmethionine

A dipeptide composed of L-glutamic acid and L-methionine joined by a peptide linkage.


Biphenyl

A benzenoid aromatic compound that consists of two benzene rings connected by a single covalent bond. Biphenyl occurs naturally in coal tar, crude oil, and natural gas. Formerly used as a fungicide for citrus crops.


Hexyl propionate

A propanoate ester of hexan-1-ol.


D-Citronellol

A citronellol that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7 (the 3R-enantiomer).


(-)-Citronellol

A  citronellol that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7 (the 3S-enantiomer).


Tartronic acid

A dicarboxylic acid that is malonic acid substituted by a hydroxy group at position 2.


CDK1_HUMAN Cyclin-dependent kinase 1 (sprot)

A cyclin-dependent kinase 1 that is encoded in the genome of human.


CDK2_HUMAN Cyclin-dependent kinase 2 (sprot)

A cyclin-dependent kinase 2 that is encoded in the genome of human.


Olomoucine

A 9H-purine that is substituted by a (2-hydroxyethyl)nitrilo, benzylnitrilo and a methyl group at positions 2,6 and 9, respectively. It is a  cyclin-dependent kinase inhibitor.


Methyl hexanoate

A fatty acid methyl ester derived from hexanoic (caproic acid).


A member of the class of oxindoles that is 2-oxindole carrying a carboxymethyl substituent at position 3.


Menthol

Any secondary alcohol that is one of the eight possible diastereoisomers of 5-methyl-2-(propan-2-yl)cyclohexan-1-ol.


alpha-PHELLANDRENE

One of a pair of phellandrene cyclic monoterpene double-bond isomers in which both double bonds are endocyclic (cf. alpha-phellandrene, where one of them is exocyclic).


A  heptenone that is hept-5-en-2-one substituted by a methyl group at position 6. It is a volatile oil component of citronella oil, lemon-grass oil and palmarosa oil.


Pyrrole

A tautomer of pyrrole that has the double bonds at positions 2 and 4.


Isobutyl hexanoate

A hexanoate ester resulting from the formal condensation of hexanoic acid (caproic acid) with isobutanol.


alpha-Cubebene

A tricyclic sesquiterpene with formula C15H24, isolated from Hungarian thyme, citrus fruit, chamomile, and several other flowering plants.


beta-Ionone

An ionone that is but-3-en-2-one substituted by a 2,6,6-trimethylcyclohex-1-en-1-yl group at position 4.


Chrysin

A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7.


A pentahydroxyflavone that is luteolin with an additional hydroxy group at position 6.


Caryophyllene

A beta-caryophyllene in which the stereocentre adjacent to the exocyclic double bond has S configuration while the remaining stereocentre has R configuration. It is the most commonly occurring form of beta-caryophyllene, occurring in many essential oils, particularly oil of cloves.


Terpinolene

A p-menthadiene with double bonds at positions 1 and 4(8).


Dihydrooroxylin A

A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 6. Isolated from Pisonia aculeata, it exhibits antitubercular activity.


10-Hydroxystearic acid

A hydroxy fatty acid that is octadecanoic acid carrying a hydroxy group at position 10.


17-Methyloctadecanoic acid

A branched-chain saturated fatty acid that is octadecanoic (stearic) acid carrying a methyl substituent at position 17.


Kaempferide

A monomethoxyflavone that is the 4'-O-methyl derivative of kaempferol.


Dihydroisorhamnetin

A tetrahydroxyflavanone that is taxifolin in which the hydroxy group at position 3' is substituted by a methoxy group. It is a metabolite of taxifolin.


Octyl acetate

The acetate ester of octan-1-ol.


Pentyl acetate

An acetate ester of pentanol.


Pyroglutamylglutamine

A dpeptide obtained by formal condensation of the carboxy group of L-pyroglutamine with the amino group of L-glutamine


Propyl butyrate

A butyrate ester resulting from the formal condensation of the hydroxy group of propanol with the carboxy group of butyric acid.


Butyl butyrate

A butanoate ester of butan-1-ol.


Ethyl hexanoate

A fatty acid ethyl ester obtained by the formal condensation of hexanoic acid with ethanol.


A 2-undecenal in which the C=C bond has E configuration.


p-Coumaraldehyde

A cinnamaldehyde that is (E)-cinnamaldehyde substituted at position 4 on the phenyl ring by a hydroxy group.


Allyl methyl disulfide

An  organic disulfide having allyl and methyl as the two organic groups.


beta-Lactose

The beta-anomer of lactose.


Orobol

A member of the class of  7-hydroxyisoflavones which consists of isoflavone substituted by hydroxy groups at positions 5, 7, 3' and 4'. It has been isolated from the mycelia of Cordyceps sinensis.


3,4-Dihydroxyphenyllactic acid methyl ester


A butan-4-olide that is gamma-valerolactone in which one of the methyl hydrogens has been replaced by a 3,4,5-trihydroxyphenyl group.


An organic sulfate that is the 3-O-sulfate derivative of trans-resveratrol.


A member of the class of nitrosamines that is butan-1-ol substituted by a pyridin-3-yl group at position 1 and by a methyl(nitroso)amino group at position 4. It is a major metabolite of nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), which is a carcinogen found in tobacco and responsible for inducing lung cancer in smokers.


Acetylisoniazid

A carbohydrazide resulting from the formal condensation of the carboxy group of isonicotinic acid with hydrazine and subsequent acetylation of the monosubstituted nitrogen atom.


Acrolein

An enal that is prop-2-ene with an oxo group at position 1.


AMMONIUM CATION

An onium cation obtained by protonation of ammonia.


Bufotenine

A tertiary amine that consists of N,N-dimethyltryptamine bearing an additional hydroxy substituent at position 5.


Doxorubicinol

A member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties.


Enalaprilat

Enalapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid. Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor and is used (often in the form of its prodrug, enalapril) in the treatment of hypertension and heart failure, for reduction of proteinuria and renal disease in patients with nephropathies, and for the prevention of stroke, myocardial infarction, and cardiac death in high-risk patients. Unlike enalapril, enalaprilat is not absorbed by mouth but is given by intravenous injection, usually as the dihydrate.


A imidazolidine-2,4-dione that consists of hydantoin bearing phenyl and 4-hydroxyphenyl substituents at position 5.


A dichlorobenzene carrying chloro groups at positions 1 and 4.


Quinaprilat

A dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril.


Tectorigenin

A methoxyisoflavone that is  isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively.


Trichloroacetic Acid

A monocarboxylic acid that is acetic acid in which all three methyl hydrogens are substituted by chlorine.


Trimethylselenonium

An organic cation consisting of three methyl groups covalently bound to a central selenium atom.


Trimyristin

A triglyceride obtained by formal acylation of the three hydroxy groups of glycerol by myristic (tetradecanoic) acid.


A triacyl-sn-glycerol in which the acyl groups at positions 1 and 2 are specified as oleoyl while that at position 3 is specifed as myristoyl.


5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid, 2-[(1-oxotetradecyl)oxy]-1-[[(1-oxotetradecyl)oxy]methyl]ethyl ester


Octadecanoic acid, 2-[(1-oxohexadecyl)oxy]-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester


Eicosanoic acid, 2-[(1-oxohexadecyl)oxy]-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester


9-Hexadecenoic acid, 2-[(1-oxohexadecyl)oxy]-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester, (9Z)-


A triglyceride in which the 1- and 3-acyl groups are palmitoyl while that at position 2 is oleoyl.


Glycerol 1-octadecanoate 2-(9Z-octadecenoate) 3-hexadecanoate


5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid, 2-[(1-oxohexadecyl)oxy]-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester


4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, 2-[(1-oxohexadecyl)oxy]-1-[[(1-oxohexadecyl)oxy]methyl]ethyl ester


A triglyceride having stearoyl (octadecanoyl) groups at positions 1 and 3 and a palmitoyl (hexadecanoyl) group at position 2. It is a metabolite of the nematode Caenorhabditis elegans.


A triglyceride in which the acyl groups at positions 1 and 3 are specified as oleoyl while that at position 2 is specified as palmitoyl.


tetracosanoic acid, 2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-1-[[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]methyl]ethyl ester


9,12-Octadecadienoic acid (9Z,12Z)-, 1,1'-[2-[(1-oxohexadecyl)oxy]-1,3-propanediyl] ester


9,12-Octadecadienoic acid, 1,1'-[2-[(1-oxooctadecyl)oxy]-1,3-propanediyl] ester


Trilinolenin

A triglyceride formed by acylation of the three hydroxy groups of glycerol with linolenic acid.


A 1,3-diglyceride in which the 1- and 3-acyl groups are specified as palmitoyl and stearoyl respectively (the R-enantiomer).


A 1,3-diglyceride in which the acyl groups at positions 1 and 3 are specified as palmitoyl and oleoyl respectively (the R-stereoisomer).


Tetracosanoic acid, 2-hydroxy-1,3-propanediyl ester


A 1,3-diglyceride with both acyl groups specified as oleoyl.


(11Z,11'Z)-11-eicosenoic acid, 2-hydroxy-1,3-propanediyl ester


(15Z,15'Z)-15-tetracosenoic acid, 1,1'-(2-hydroxy-1,3-propanediyl) ester


A 1,3-diglyceride in which both acyl groups are specified as linolenoyl.


(4'Z,7'Z,10'Z,13'Z,16'Z,19'Z)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, diester with 1,2,3-propanetriol


Tetrahexadecanoyl cardiolipin

A cardiolipin in which all four of the phosphatidyl acyl groups are specified as hexadecanoyl (pamitoyl).


Tetrastearoylcardiolipin

A cardiolipin derivative in which all four of the phosphatidyl acyl groups are specified as stearoyl (octadecanoyl).


A purine 2'-deoxyribonucleoside 5'-triphosphate in which the 2'-deoxyribonucleoside moiety is 2'-deoxy-2-hydroxyadenosine.


A purine 2'-deoxyribonucleoside 5'-monophosphate in which the purine moiety is 2-hydroxyadenine.


Hydron

The general name for the hydrogen nucleus, to be used without regard to the hydrogen nuclear mass (either for hydrogen in its natural abundance or where it is not desired to distinguish between the isotopes).


CDP-glycerol

A nucleotide-alditol having cytidine-5'-diphosphate and glycerol as the nucleotide and alditol components respectively.


The 5-phosphonooxy derivative of L-lysine having erythro-stereochemistry.


An indanone that consists of 2,3-dihydro-1H-indene substituted by an oxo group at position 1.


Chlordecone

An  organochlorine compound with insecticidal activity.


A ketocholestane that is cholestane which carries an oxo group at position 3.


CRYM_HUMAN Ketimine reductase mu-crystallin (sprot)

A ketimine reductase mu-crystallin that is encoded in the genome of human.


Thiomorpholine-3-carboxylic acid

A thiomorpholinemonocarboxylic acid having the carboxy group at the 3-position.


7-Methylguanosine 5'-diphosphate

A guanosine 5'-phosphate that consists of guanosine 5'-diphosphate bearing a 7-methyl substituent.


A polyprenol diphosphate compound having ten prenyl units with undefined stereochemistry about the double bonds.


(S)-ethylmalonyl-CoA

An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of (2S)-ethylmalonic acid.


Hymecromone

A hydroxycoumarin that is umbelliferone substituted by a methyl group at position 4.


beta-L-Fucose

A L-fucopyranose with a beta-configuration at the anomeric position.


The alpha-anomer of N-acetyl-D-galactosamine 1-phosphate.


Adenylyl-molybdopterin

A molybdopterin dinucleotide resulting from the formal condensation of the phosphate groups of molybdopterin and adenosine 5'-monophosphate to give a diphosphate linkage.


An optically active 9-(phosphonooxy)-10-hydroxy derivative of stearic acid with (9S,10S)-configuration.


(9S,10S)-9,10-dihydroxystearic acid

A 9,10-dihydroxyoctadecanoic acid diastereoisomer in which both stereocentres have S configuration.


Hydriodic acid

A diatomic molecule containing covalently bonded hydrogen and iodine atoms.


lipoyl-AMP

A purine ribonucleoside 5'-monophosphate having adenine as the nucleobase and a lipoyl group attached to one of the phosphate OH groups.


A 2-hydroxy monocarboxylic acid that is lactic acid substituted by a 4-hydroxy-3,5-diiodophenyl group at position 3.


A derivative of pyruvic acid carrying a 3,5-diiodo-4-hydroxyphenyl group at the 3-position.


A guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.


MOC2A_HUMAN Molybdopterin synthase sulfur carrier subunit (sprot)

A molybdopterin synthase sulfur carrier subunit that is encoded in the genome of human.


Cyclic pyranopterin monophosphate

A linear-fused organic heterotetracyclic compound consisting of a [1,3,2]dioxaphosphinane fused to a pyran ring which is in turn fused to a pteridine ring system. Molybdenum cofactor biosynthesis intermediate. Dehydrated derivative known as precursor Z.


A nucleoside pentaphosphate that is adenosine in which a hexahydrogen pentaphosphate is attached at the 5' position.


A purine 2'-deoxyribonucleoside 5'-diphosphate having 8-oxoguanine as the nucleobase.


The 2-(3,4-dihydroxybenzoyl) derivative of 2,4,6-trihydroxybenzoic acid. A metabolite of quercetin, an abundant flavonoid found in edible vegetables, grains and fruits which is used as an ingredient in supplements, beverages, or foods.


DNPH1_HUMAN 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 (sprot)

A 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 that is encoded in the genome of human.


2-Hydroxyglutaric acid

A 2-hydroxydicarboxylic acid that is glutaric acid in which one hydrogen alpha- to a carboxylic acid group is substituted by a hydroxy group.


The (3S)-trans-diastereomer of 3-hydroxy-L-proline.


Nonanal

A saturated fatty aldehyde formally arising from reduction of the carboxy group of nonanoic acid. Metabolite observed in cancer metabolism.


A derivative of toluene bearing an additional ethyl substituent at position 3.


O-Xylene

A xylene substituted by methyl groups at positions 1 and 2.


A dimethylnaphthalene carrying methyl groups at positions 1 and 7.


An alkene that is dodecane containing one double bond at position 1. It is an intermediate used in the production of lubricants and surfactants.


Pentadecane

A straight-chain alkane with 15 carbon atoms. It is a component of volatile oils isolated from plants species like Scandix balansae.


Trimethylbenzene

A trimethylbenzene carrying methyl groups at positions 1, 2 and 3. It has been found in  Centaurium erythraea.


Ethylbenzene

An  alkylbenzene carrying an ethyl substituent. It is a constituent of coal tar and petroleum.


Tetradecane

A straight chain alkane consisting of 14 carbon atoms.


Acetaminophen sulfate

An aryl sulfate that is paracetamol in which the hydroxy group has been replaced by a sulfooxy group.


P-Xylene

A xylene with methyl groups at positions 1 and 4.


3-Hydroxy-4-methoxybenzoic acid

A methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3.


Phenyl hydrogen sulfate

An aryl sulfate that is phenol bearing an O-sulfo substituent.


cis-10-Heptadecenoic acid

The cis-isomer of 10-heptadecenoic acid.


cis-coumarinic acid-beta-D-glucoside

A beta-D-glucoside consisting of cis-2-coumaric acid having a beta-D-glucosyl residue attached to the phenolic hydroxy group.


Prostaglandin C2

A member of the class of prostaglandins C that is prosta-5,11,13-trien-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 5Z,13E,15S-stereoisomer).


A 7alpha,24-dihydroxycholesterol in which has S configuration at position 24.


A cyanoamino acid that is the 3-cyano-derivative of L-alanine.


An organic cation that is 1-pyrroline bearing an N-methyl substituent.


4-Nitrophenyl phosphate

An aryl phosphate resulting from the mono-esterification of phosphoric acid with 4-nitrophenol.


A hydroxykynurenamine that is kynurenamine carrying a hydroxy group at position 3. It is a metabolite of tryptophan that exhibits antiinflammatory and immunomodulatory properties.


Hydrogen Cyanide

A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom


luteolin 7-O-[(beta-D-glucosyluronic acid)-(1->2)-(beta-D-glucosiduronic acid)] 4'-O-beta-D-glucosiduronic acid

A luteolin glucosiduronic acid that consists of luteolin substituted by a beta-D-glucopyranosyluronic acid-(1->2)-beta-D-glucopyranosiduronic acid group at position 7 and a beta-D-glucopyranosyluronic acid group at position 4' via glycosidic linkages.


The glycosyloxyflavone resulting from the condensation of the hydroxy group at position 7 of luteolin with the 1 position of 2-O-beta-D-glucopyranuronosyl-beta-D-glucopyranosiduronic acid.


(1S,2R)-Naphthalene 1,2-oxide

A naphthalene 1,2-oxide (the 1S,2R-stereoisomer).


A naphthylmethanol that is methanol in which one of the methyl hydrogens has been replaced by a (2-naphthyl) group.


A 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA in which the carbon at position 25 of the steroidal side chain has R configuration.


A 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA in which the carbon at position 25 of the steroidal side chain has S configuration.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoic acid.


The (2R)-enantiomer of 2-hydroxy-2-methylbutanenitrile.


An omega-carboxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of (R)-ethylmalonic acid.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (5Z,8Z,11Z,14Z,17Z)-icosapentaenoic acid. It is a member of n-3 PUFA and by-product of alpha-linolenic acid metabolism.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (6Z,9Z,12Z,15Z,18Z,21Z)-3-hydroxytetracosahexaenoic acid. It is a member of n-3 PUFA and a product of alpha-linolenoic acid metabolism.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (6Z,9Z,12Z,15Z,18Z,21Z)-3-oxotetracosahexaenoic acid. It is a member of n-3 PUFA and a product of alpha-linolenoic acid metabolism.


An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (6Z,9Z,12Z,15Z,18Z)-3-oxotetracosapentaenoic acid.


A cephalosporin having an acetoxy group at the 3-position and a 5-carboxy-5-oxopentanamido group at the 7-position.


A 4-hydroxymandelonitrile that has (S)-configuration.


(S)-N-Methylcoclaurine

The (S)-enantiomer of N-methylcoclaurine.


A naphthylmethanol that is methanol in which one of the hydrogens of the methyl group is replaced by a naphthalen-1-yl group.


A naphthaldehyde with a formyl group at position 1.


A bromoalkane that is ethane carrying bromo substituents at positions 1 and 2. It is produced by marine algae.


A member of the class of naphthalenediols that is 1,2-dihydronaphthalene substituted by hydroxy groups at positions 1 and 2 respectively.


1,4'-Bipiperidine-1'-carboxylic acid

A monocarboxylic acid resulting from the formal condensation of the amino group of 1,4'-bipiperidine with carbonic acid.


11-cis-Retinyl palmitate

The 11-cis-isomer of retinyl palmitate.


An androstanoid that is testosterone carrying an additional hydroxy substituent at the 11beta-position.


A carotenol obtained by formal dihydroxylation across the 15,15'-double bond of beta-carotene.


A 4-oxohex-2-enedioic acid with a Z-configuration.


A naphthaldehyde that is naphthalene substituted by a formyl group at position 2.


2-Oxosuccinamic acid

A dicarboxylic acid monoamide that is  succinamic acid substituted by an oxo group at position 2.


A member of the class of amino-nitrotoluenes that is 2,4-diaminotoluene bearing a nitro substituent at position 6.


4,6-Dioxohept-2-enedioic acid

A  4,6-dioxohept-2-enedioic acid that is pyruvic acid substituted at position 3 by a fumaryl group.


The S-3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl derivative of CoA.


2-Amino-3-methoxybenzoic acid

An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 3 is substituted by a methoxy group. It is a metabolite of kynurenine.


The S-(3-oxoadipyl) derivative of coenzyme A.


A member of the class of amino-nitrotoluenes that is 2-amino-6-nitrotoluene bearing an additional acetamido group at position 4.


3-Geranyl-4-hydroxybenzoic acid

A monohydroxybenzoic acid having the hydroxy group at the 4-position together with a geranyl group at the 3-position.


4-Hydroxyphenyl acetate

A phenyl acetate obtained by formal condensation of the carboxy group of acetic acid with one of the hydroxy groups of hydroquinone.


An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of trans-2,3-didehydroadipic acid.


A 5-deoxyribose phosphate consisting of 5-deoxy-alpha-D-ribose having the phospho group located at the 1-position.


An organofluorine compound that is uridine bearing a fluoro substituent at position 5 on the uracil ring.


5-Fluorouridine monophosphate

A pyrimidine ribonucleoside 5'-monophosphate having 5-fluorouracil as the pyrimidine component.


5-Hydroxyconiferyl alcohol

A 5-hydroxyconiferyl alcohol in which the double bond has E geochemistry.


Doxifluridine

A pyrimidine 5'-deoxyribonucleoside that is 5-fluorouridine in which the hydroxy group at the 5' position is replaced by a hydrogen. It is an  oral prodrug of the antineoplastic agent 5-fluorouracil. Designed to circumvent the rapid degradation of 5-fluorouracil by dihydropyrimidine dehydrogenase in the gut wall, it is converted into 5-fluorouracil in the presence of pyrimidine nucleoside phosphorylase.


A 3-oxo-5alpha-steroid formed from 11-deoxycorticosterone by reduction across the C4-C5 double bond.


A 5,6,7,8-tetrahydropterin having a carboxy group at the 6-position.


A thiopurine that is 9H-purine substituted by a methylsulfanyl group at position 6.


A 3-oxo-fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of 7-methyl-3-oxooct-6-enoic acid.


A glutathione derivative in which the hydrogen of the side-chain thiol function of glutathione is substituted by a 7-hydroxy-7,8-dihydrobenzo[pqr]tetraphen-8-yl group.


A 20-oxo steroid that is pregnenolone carrying an additional hydroxy substituent at the 7alpha-position.


A cholestanoid that is 4-cholesten-3-one carrying two additional hydroxy substituents at positions 7alpha and 25.


Xanthurenic acid 8-methyl ether

A quinolinemonocarboxylic acid that is kynurenic acid which is substituted by a methoxy group at position 8.


Acethydrazide

A carbohydrazide that is hydrazine in which one of the hydrogens is replaced by an acetyl group.


beta-Alanyl-L-lysine

A dipeptide consisting of beta-alanine and L-lysine units joined by a peptide linkage.


An epoxycarotenoid obtained by epoxidation across the 15,15'-double bond of beta-carotene.


cephalosporin C

A cephalosporin antibiotic carrying a 3-acetoxymethyl substituent and a 6-oxo-N(6)-L-lysino group at position 7.


Chloral Hydrate

An organochlorine compound that is the hydrate of trichloroacetaldehyde.


An oligosaccharide sulfate that is 2-acetamido-2-deoxy-6-O-sulfo-beta-D-galactopyranose in which the hydroxy group at position 3 has been converted into the corresponding beta-D-glucopyranuronoside.


A 4-hydroxy-D-proline in which the hydroxy group at position 4 has R-configuration.


cis-Acetylacrylic acid

A 4-oxo monocarboxylic acid that is (Z)-pent-2-enoic acid in which the 4-position has been oxidised to the corresponding ketone.


Cgamp

A cyclic purine dinucleotide that consists of AMP and GMP units cyclised via 3',5'-linkages.


A 4-hydroxy-2-oxoglutaric acid having D-configuration.


The open chain form of D-fructose 1-phosphate.


D-Gal alpha 1->6D-Gal alpha 1->6D-Glucose

A trisaccharide consisting of two alpha-D-galactopyranose residues and a D-glucopyranose residue joined in sequence by (1->6) glycosidic bonds.


Dhurrin

A beta-D-glucoside consisting of (S)-prunasin carrying a hydroxy substituent at position 4 on the phenyl ring.


GLUTAMIC ACID, DL-

An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2.


Caprolactone

A epsilon-lactone that is oxepane substituted by an oxo group at position 2.


A nitrile that is L-glutamine in which one of the hydrogens attached to the amide nitrogen is replaced by a 2-cyanoethyl group.


gamma-Glutamyl-beta-cyanoalanine

A dipeptide composed of 3-cyano-L-alanine and L-glutamine joined by a peptide linkage formed from the side-chain of glutamine.


A guanosine bisphosphate having a diphosphate at the 3'-position and a triphosphate at the 5'-position.


Heparan sulfate alpha-D-glucosaminide

A heparan sulfate having an alpha-D-glucosaminyl residue at the non-reducing end. The heparan sulfate part consists of a variably sulfated repeating disaccharide unit.


A hexadecenal containing a double bond at position 2 (the trans-stereoisomer).


Indole-3-pyruvic acid

A 2-oxo monocarboxylic acid that is pyruvic acid substituted by a 1H-indol-3-yl group at position 3. It has been found in Lycopersicon esculentum


Menaquinol

Any polyprenylhydroquinone having a polyprenyl moiety at position 2 and a methyl group at position 3..


Methylselenium(II)

An organoselenium compound that is a selenium analogue of methanol, comprising a methyl group covalently bound to a selenol group.


Methylselenic acid

An organoselenium compound that is seleninic acid in which the hydrogen attached to selenium is replaced by a methyl group.


Mycophenolic acid acyl glucuronide

A carboxylic ester resulting from the formal condensation of the carboxylic acid group of mycophenolic acid with the anomeric hydroxy group of beta-D-glucuronic acid.


N-Acetyl-Muramic Acid

The pyranose form of N-acetylmuramic acid.


N-Formyl-L-aspartic acid

A N-formyl amino acid that is the N-formyl-derivative of L-aspartic acid.


[[(2R,3S,4R,5S)-3,4-dihydroxy-5-methyloxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate


An optically active form of 1,2-distearoylphosphatidylethanolamine having (S)-configuration.


A member of the class of pyranoindolizinoquinolines that is (4S)-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione bearing two additional ethyl substituents at positions 4 and 11 as well as two additional hydroxy substituents at positions 4 and 9. It is the active metabolite of irinotecan and is ~1000 times more active than irinotecan itself.


Sterol

Any 3-hydroxy steroid whose skeleton is closely related to cholestan-3-ol (additional carbon atoms may be present in the side chain).


Tamoxifen N-oxide

A tertiary amine oxide resulting from the formal oxidation of the amino group of tamoxifen.


A butenolide having a carboxymethylene group at the 4-position.


Trypanothione

An organic disulfide resulting from the formal oxidative coupling of the thiol groups of N(1),N(8)-bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid Crithidia fasciculata.


A UDP-N-acetyl-D-galactosamine in which the anomeric centre of the galactosamine moiety has alpha-configuration.


Afimoxifene

A tertiary amino compound that is tamoxifen in which the phenyl group which is in a Z- relationship to the ethyl substituent is hydroxylated at the para- position. It is the active metabolite of tamoxifen.


Carboxyibuprofen

A dicarboxylic acid that is ibuprofen in which one of the methyl groups in the isobutyl portion has been converted to the corresponding carboxylic acid.


The (10S,11S)-enantiomer of 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine.


Perindoprilat

A dipeptide obtained by formal condensation of one of the carboxy groups of N-[(1S)-1-carboxyethyl]-L-norvaline with the amino group of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid. The major active metabolite of perindopril.


Ramiprilat

A dipeptide that is the active metabolite of ramipril. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.


Benazeprilat

A benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino group of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure.


Trandolaprilat

A heterobicyclic compound that is trandolapril in which the ethyl ester group has been hydrolysed to the corresponding acid group. It is the active metabolite of the prodrug trandolapril.


A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a morpholin-4-yl group.


Monoethylglycinexylidide

Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.


Norcodeine

A morphinane-like compound that is the N-demethylated derivative of codeine.


An  epoxide and metabolite of carbamazepine.


Licarbazepine

A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.


A primary arylamine that is aniline in which the hydrogens at the 2- and 6-positions are replaced by methyl groups. It is used in the production of some anasthetics and other chemicals. It is a drug metabolite of lidocaine (local anasthetic).


Glycinexylidide

A amino acid amide with 2,6-dimethylaniline and glycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.


A substituted aniline in which the aniline ring carries 4-hydroxy and 2,6-dimethyl substituents; a urinary metabolite of lidocaine.


Desmethyldoxepin

The (Z)-isomer of desmethyldoxepin.


N,O-Didesmethylvenlafaxine

A secondary amino compound that is N-methylethanamine substituted by a 1-hydroxycyclohexyl and a 4-hydroxyphenyl group at position 1. It is a metabolite of the drug venlafaxine.


A hydroxy monocarboxylic acid that is ibuprofen in which the methine proton on the isobutyl group has been replaced by a hydroxy group.


A furoic acid that is furan-3-carboxylic acid substituted by a methyl group at position 4, a propyl group at position 5 and a 2-carboxyethyl group at position 2. It is a potent uremic toxin that has been found to accumulate in human serum of patients with chronic kidney diseases.


Hypaphorine

An amino acid betaine obtaine by exhaustive methylation of the alpha-amino group of L-tryptophan with concomitant deprotonation of the carboxy group.


N-(2-Hydroxyethyl)-morpholine N-oxide

A member of the class of morpholines that is morpholine in which the amino group is substituted by a 2-hydroxyethoxy group.


Angiotensin I

A ten amino acid peptide formed by renin cleavage of angiotensinogen. Angiotensin I has no direct biological function except that high levels can stimulate catecholamine production. It is metabolized to its biologically active byproduct angiotensin II, a potent vasoconstrictor, by angiotensin converting enzyme (ACE) through cleavage of the two terminal amino acids.


Triclosan

An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes.


(S)-3-Hydroxymyristic acid

A C14, long-chain hydroxy fatty acid and enantiomer of the biologically active (R)-3-hydroxytetradecanoic acid.


N-Acetyl-L-isoleucine

An N-acetyl-L-amino acid that is L-isoleucine in which one of the nitrogens attached to the nitrogen is replaced by an acetyl group.


A lysophosphatidylcholine 18:1 in which the acyl group is specified as oleoyl and is located at position 2.


6-Oxopiperidine-2-carboxylic acid

A delta-lactam that is piperidine-2-carboxylic acid substituted at position 6 by an oxo group.


13-Methyltetradecanoic acid

A branched-chain saturated fatty acid comprising tetradecanoic (myristic) acid substituted at position 13 by a methyl group.


15-Methylhexadecanoic acid

A branched-chain saturated fatty acid comprising hexadecanoic (palmitic) acid substituted at position 15 by a methyl group.


Methyl dihydrogen phosphate

A monoalkyl phosphate having methyl as the alkyl group.


13Z,16Z-docosadienoic acid

A docosadienoic acid having two cis-double bonds at position 13 and 16 respectively.


A piperidine compound having a (2-thienyl)ethyl substituent at the 1-position, a methyl group at the 3-position and an N-phenylpropanamido group at the 4-position.


Dimethylthiambutene

N,N-Dimethylbut-3-en-2-amine in which each of the hydrogens at position 4 is substituted by a 2-thienyl group. An opioid analgesic drug, it is controlled under the UN Single Convention on Narcotic Drugs (1961), but is used in veterinary medicine, particularly in Japan.


Temocapril Metabolism Pathway,Drug Metabolism


Carbovir triphosphate

The organic triphosphate that is the 5'-triphosphate of (-)-carbovir.


Rilpivirine

An aminopyrimidine that is pyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 4-cyanophenyl and 4-[(E)-2-cyanovinyl]-2,6-dimethylphenyl groups respectively. Used for treatment of HIV.


10Z,12Z-octadecadienoic acid

A octadecadienoic acid with unsaturation at positions 10 and 12 (the 10Z,12Z-stereoisomer).


A hexanol in which the hydroxy group is at position 2.


8-Hydroxyoctanoic acid

An omega-hydroxy fatty acid that is caprylic acid in which one of the hydrogens of the terminal methyl group is replaced by a hydroxy group.


Oxindole

An indolinone carrying an oxo group at position 2.


5-Hydroxypentanoic acid

An omega-hydroxy fatty acid consisting of pentanoic acid carrying a hydroxy group at C-5.


A monocarboxylic acid that is propanoic acid in which one of the hydrogens at position 3 has been replaced by a 4-hydroxy-3-methoxyphenyl group.


N-lactoyl-phenylalanine

A L-phenylalanine derivative that is L-phenylalanine in which the amino group is replaced by a [(2S)-2-hydroxypropanoyl]amino group. It is a metabolite produced as a result of exercise in mice, racehorses, and humans which suppresses feeding and obesity.


Acadesine

A 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is  is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects.


Erucoyl-coa

An unsaturated fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of erucic acid.


A very long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (15Z)-tetracosenoic acid.


Gadoleic Acid

An icosenoic acid having a cis- double bond at position 9.


2-Hydroxyacetaminophen sulfate

An aryl sulfate that is the 3-hydroxy derivative of  paracetamol sulfate.


(S)-2-hydroxystearic acid

An optically active form of 2-hydroxyoctadecanoic acid having (S)-configuration.


4-Ethylphenyl hydrogen sulfate

An aryl sulfate that is 4-ethylphenol in which the hydroxy group has been replaced by a sulfooxy group.


N-Acetylthreonine

A N-acetyl-L-amino acid that is the N-acetyl derivative of L-threonine.


2-Propenoic acid, 3-(1H-imidazol-4-yl)-

An alpha,beta-unsaturated monocarboxylic acid that is prop-2-enoic acid substituted by a 1H-imidazol-4-yl group at position 3. It is a metabolite of hidtidine.


Tropic acid

A 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a phenyl group, and one of the methyl hydrogens is substituted by a hydroxy group.


Meta-hydroxyphenylhydracrylic acid

A hydroxy monocarboxylic acid that is propionic acid substituted by a hydroxy group at position 3 and a 3-hydroxyphenyl group at position 2. It is a metabolite of flavonoids and has been identified as one of the major phenolic acids in human urine.


Linoleamide

A fatty amide obtained from  linoleic acid.


Epiandrosterone sulfate

A steroid sulfate that is the 3-sulfate of epiandrosterone.


N-Methyl-L-glutamic acid

A N-methyl-L-alpha-amino acid with L-glutamic acid as the amino acid component.


Thymol sulfate

An organic sulfate of thymol.


(S)-2-Aminoheptanoic acid

An optically active form of 2-aminoheptanoic acid having L-configuration.


Pregnane-3,20-diol 3,20-disulfate

A steroid sulfate that is 5alpha-pregnane-3beta,20alpha-diol in which both hydroxy hydrogens have been replaced by sulfo groups.


Pyroglutamylvaline

A dipeptide obtained by formal condensation of the carboxy group of pyroglutamic acid with the amino group of valine.


Diethyl Phthalate

The diethyl ester of benzene-1,2-dicarboxylic acid.


A ketone that is hexylbenzene carrying an oxo group at position 2.


Cyclo(L-leucyl-L-phenylalanyl)

A member of the class of 2,5-diketopiperazines that is piperazine-2,5-dione in which one hydrogen at position 3 and one hydrogen at position 6 are replaced by benzyl and isobutyl groups (the 3S,6S-diastereomer).


An androstane sulfate that is 5alpha-androstan-3alpha,17beta-diol in which both hydroxy hydrogens have been replaced by sulfo groups.


Cetyl benzoate

A benzoate ester resulting from the formal condensation of the carboxy group of benzoic acid with the hydroxy group of hexadecan-1-ol.


An O-acylcarnitine in which the acyl group is specified as 2-octadecenoyl.


N-propionylmethionine

An N-acyl-L-alpha-amino acid obtained by formal condensation of the carboxy group of propanoic acid with the amino group of L-methionine.


3,5-Dihydroxyphenylacetic acid

A monocarboxylic acid that is phenylacetic acid carrying two hydroxy substituents at positions 3 and 5 on the benzene ring.


3-(3-sulfooxyphenyl)propanoic Acid

A monocarboxylic acid that is propionic acid carrying a 3-sulfooxyphenyl substituent at C-3.


myristoleoyl-CoA

An unsaturated fatty acyl-CoA resulting from the formal condensation of the thiol group of coenzyme A with the carboxy group of (9Z)-myristoleic acid.


isotridecanoyl-CoA

A methyl-branched fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of isotridecanoic acid


isotetradecanoyl-CoA

A long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of isomyristic acid.


isopentadecanoyl-CoA

A methyl-branched fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of isopentadecanoic acid.


isohexadecanoyl-CoA

A methyl-branched fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of isopalmitic acid


isoheptadecanoyl-coA

A methyl-branched fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of isoheptadecanoic acid.


A 1,2-diacyl-sn-glycero-3-phosphate in which the acyl groups at positions 1 and 2 are specified as octanoyl.


A 1-acyl-2-tetradecanoyl-sn-glycero-3-phosphate in which the 1-acyl group is specified as hexadecanoyl (palmitoyl).


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as octadecanoyl and (9Z)-hexadecenoyl respectively.


Docosanoic acid, 1-[[(1-oxooctadecyl)oxy]methyl]-2-(phosphonooxy)ethyl ester, (R)-


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as oleoyl and tetradecanoyl respectively.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as oleoyl and pentadecanoyl respectively.


A 1-acyl-2-hexadecanoyl-sn-glycero-3-phosphate in which the 1-acyl group is specified as oleoyl (9Z-octadecaenoyl).


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as (9Z)-octadecenoyl and (9Z)-hexadecenoyl respectively.


A 1-acyl-2-octadecanoyl-sn-glycero-3-phosphate in which the 1-acyl group is specified as oleoyl (9Z-octadecaenoyl).


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as oleoyl and icosanoyl (arachidoyl) respectively.


A 1,2-diacyl-sn-glycerol 3-phosphate in which the acyl substituents at positions 1 and 2 are specified as icosanoyl (arachidoyl) and oleoyl respectively.


1,2-diacyl-sn-glycerol in which both the 1- and 2-acyl groups are specified as octanoyl. Formula C19H36O5.


A member of the class of catechols that is catechol in which a hydrogen that is ortho to one of the hydroxy groups has been replaced by a methoxy group. It displays agonistic activity against G protein-coupled receptor 35 (GPR35).


Bosutinib Inhibition of BCR-ABL,Drug Action


Bosutinib

An aminoquinoline that is 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline bearing additional cyano and methoxy substituents at positions 3 and 6 respectively.


Bafetinib Inhibition of BCR-ABL,Drug Action


Ponatinib Inhibition of BCR-ABL,Drug Action


Ponatinib

A benzamide obtained by the formal condensation of the carboxy group of 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid with the anilino group of 4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline. It is a multi-target tyrosine kinase inhibitor that targets ABL, SRC, FGFR, and others and was designed to overcome the resistance of BCR-ABL mutation to imatinib, in particular the gatekeeper mutation ABL(T315I).


Vaccenic acid, cis-

The cis isomer of vaccenic acid.


Oxatomide

A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one substituted by a 3-[4-(diphenylmethyl)piperazin-1-yl]propyl group at position 1. It is an anti-allergic drug.


Acrivastine

A member of the class of pyridines that is (pyridin-2-yl)acrylic acid substituted at position 6 by a [(1E)-1-(4-methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl group. It is a non-sedating antihistamine used for treatment of hayfever, urticaria, and rhinitis.


salicyluric beta-D-glucuronide

A carboxylic ester resulting from the formal condensation of the carboxy group of salicyluric acid with the anomeric hydroxy group of beta-D-glucuronic acid.


A 1-acyl-sn-glycero-3-phospho-1D-myo-inositol in which the 1-acyl group is specified as stearoyl.


A lysophosphatidylcholine 16:0 in which the acyl group is specified as palmitoyl (hexadecanoyl) and is located at position 2.


RLME_METST Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_ECOK1 Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_EHRCR Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_NEOSM Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_BARQU Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_BARHE Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_SALPA Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_GRABC Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_ANAPZ Ribosomal RNA large subunit methyltransferase E (sprot)


TRMJ_ECOK1 tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ (sprot)


RLME_FRATN Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_WOLTR Ribosomal RNA large subunit methyltransferase E (sprot)


RLME_METS3 Ribosomal RNA large subunit methyltransferase E (sprot)


TRMJ_SALPA tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ (sprot)


A methyluridine that consists of uridine bearing a single methyl substituent located at position O-2' on the ribose ring.


ABCG2_MOUSE Broad substrate specificity ATP-binding cassette transporter ABCG2 (sprot)

A broad substrate specificity ATP-binding cassette transporter ABCG2 that is encoded in the genome of mouse.


4-Methylumbelliferone sulfate

A member of the class of coumarins that is umbelliferone sulfate which carries a methyl group at position 4. It is a metabolite of 4-methylumbelliferone.


Ectoine

A carboxamidine heterocycle obtained by formal condensation of (2S)-2,4-diaminobutanoic acid with acetic acid.


CRYM_MACFL Ketimine reductase mu-crystallin (sprot)


DTWD2_HUMAN tRNA-uridine aminocarboxypropyltransferase 2 (sprot)

A tRNA-uridine aminocarboxypropyltransferase 2 that is encoded in the genome of human.


DTWD1_HUMAN tRNA-uridine aminocarboxypropyltransferase 1 (sprot)

A tRNA-uridine aminocarboxypropyltransferase 1 that is encoded in the genome of human.


A derivative of uridine, bearing an additional 3-amino-3-carboxypropyl substituent at position 5 on the uracil ring.


RSMI_MYCTU Ribosomal RNA small subunit methyltransferase I (sprot)


TRML_PHOAA tRNA (cytidine(34)-2'-O)-methyltransferase (sprot)


RLMM_PHOAA Ribosomal RNA large subunit methyltransferase M (sprot)


RLMM_ECOK1 Ribosomal RNA large subunit methyltransferase M (sprot)


TRM56_METST tRNA (cytidine(56)-2'-O)-methyltransferase (sprot)


RLMM_SALPA Ribosomal RNA large subunit methyltransferase M (sprot)


RSMI_HELPJ Ribosomal RNA small subunit methyltransferase I (sprot)


TRM56_METS3 tRNA (cytidine(56)-2'-O)-methyltransferase (sprot)


SLS1_TRYB2 Phosphatidylinositol:ceramide inositolphosphotransferase (sprot)


SCF_RAT Kit ligand (sprot)

A kit ligand that is encoded in the genome of rat.


SLS11_TRYCC Phosphatidylinositol:ceramide inositolphosphotransferase (sprot)


SLS4_TRYBB Phosphatidylcholine:ceramide cholinephosphotransferase 4 (sprot)


SLS3_TRYB2 Phosphatidylcholine:ceramide cholinephosphotransferase 3 (sprot)


PIPS_CUTAK Phosphatidylinositol phosphate synthase (sprot)


PLCZ1_MACFA 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (sprot)


SLS3_TRYBB Phosphatidylcholine:ceramide cholinephosphotransferase 3 (sprot)


SLS2_TRYBB Phosphatidylethanolamine:ceramide ethanolaminephosphotransferase (sprot)


PLPL1_HUMAN Omega-hydroxyceramide transacylase (sprot)

An omega-hydroxyceramide transacylase that is encoded in the genome of human.


PLCZ1_RAT 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (sprot)

A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 that is encoded in the genome of rat.


PLCD4_BOVIN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (sprot)


MOGT1_MOUSE 2-acylglycerol O-acyltransferase 1 (sprot)

A 2-acylglycerol O-acyltransferase 1 that is encoded in the genome of mouse.


SLS4_TRYB2 Phosphatidylcholine:ceramide cholinephosphotransferase 4 (sprot)


SLS_LEIMA Phosphatidylinositol:ceramide inositolphosphotransferase (sprot)


M1IP1_HUMAN Mid1-interacting protein 1 (sprot)

A Mid1-interacting protein 1 that is encoded in the genome of human.


KDGL_HELPJ Diacylglycerol kinase (sprot)


PGFRA_RAT Platelet-derived growth factor receptor alpha (sprot)

An alpha-type platelet-derived growth factor receptor that is encoded in the genome of rat.


PLPP1_MOUSE Phospholipid phosphatase 1 (sprot)

A phospholipid phosphatase 1 that is encoded in the genome of mouse.


PI51A_HUMAN Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (sprot)

A phosphatidylinositol 4-phosphate 5-kinase type-1 alpha that is encoded in the genome of human.


PGFRB_RAT Platelet-derived growth factor receptor beta (sprot)

A beta-type platelet-derived growth factor receptor that is encoded in the genome of rat.


PLCZ1_MOUSE 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 (sprot)

A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 that is encoded in the genome of mouse.


LIPR2_CAVPO Pancreatic lipase-related protein 2 (sprot)


LIPR2_MOUSE Pancreatic lipase-related protein 2 (sprot)

A pancreatic lipase-related protein 2 that is encoded in the genome of mouse.


SLS1_TRYBB Phosphatidylinositol:ceramide inositolphosphotransferase (sprot)


SCF_HUMAN Kit ligand (sprot)

A kit ligand that is encoded in the genome of human.


SLS2_TRYB2 Phosphatidylethanolamine:ceramide ethanolaminephosphotransferase (sprot)


ATG15_CRYNJ Putative lipase ATG15 (sprot)


FITM2_HUMAN Acyl-coenzyme A diphosphatase FITM2 (sprot)

An acyl-coenzyme A diphosphatase FITM2 that is encoded in the genome of human.


ABHGA_HUMAN Phosphatidylserine lipase ABHD16A (sprot)

A phosphatidylserine lipase ABHD16A that is encoded in the genome of human.


AAAD_MOUSE Arylacetamide deacetylase (sprot)

An arylacetamide deacetylase that is encoded in the genome of mouse.


FITM1_HUMAN Fat storage-inducing transmembrane protein 1 (sprot)

A fat storage-inducing transmembrane protein 1 that is encoded in the genome of human.


ATG15_COCIM Putative lipase ATG15 (sprot)


AGK_DANRE Acylglycerol kinase, mitochondrial (sprot)

An acylglycerol kinase, mitochondrial that is encoded in the genome of zebrafish.


ATG15_AJECN Putative lipase ATG15 (sprot)


CERT_DANRE Ceramide transfer protein (sprot)

A protein that is a translation product of the col4a3bpa gene in zebrafish.


DGKA_PIG Diacylglycerol kinase alpha (sprot)


ATG15_CRYNB Putative lipase ATG15 (sprot)


DAGK_STAHJ Diacylglycerol kinase (sprot)


DGAT2_MOUSE Diacylglycerol O-acyltransferase 2 (sprot)

A diacylglycerol O-acyltransferase 2 that is encoded in the genome of mouse.


DGAT1_RAT Diacylglycerol O-acyltransferase 1 (sprot)

A diacylglycerol O-acyltransferase 1 that is encoded in the genome of rat.


AAAD_RAT Arylacetamide deacetylase (sprot)

An arylacetamide deacetylase that is encoded in the genome of rat.


DGAT1_MOUSE Diacylglycerol O-acyltransferase 1 (sprot)

A diacylglycerol O-acyltransferase 1 that is encoded in the genome of mouse.


GRP4_RAT RAS guanyl-releasing protein 4 (sprot)

A RAS guanyl-releasing protein 4 that is encoded in the genome of rat.


AVIL_HUMAN Advillin (sprot)

An advillin that is encoded in the genome of human.


ABHD2_HUMAN Monoacylglycerol lipase ABHD2 (sprot)

A monoacylglycerol lipase ABHD2 that is encoded in the genome of human.


ABHGA_MOUSE Phosphatidylserine lipase ABHD16A (sprot)

A phosphatidylserine lipase ABHD16A that is encoded in the genome of mouse.


DGKQ_RAT Diacylglycerol kinase theta (sprot)

A diacylglycerol kinase theta that is encoded in the genome of rat.


KPCB_BOVIN Protein kinase C beta type (sprot)


LIP3_ARTBC Probable secreted lipase ARB_02369 (sprot)


LPIN3_MUSSP Phosphatidate phosphatase LPIN3 (sprot)


NEPR1_HUMAN Nuclear envelope phosphatase-regulatory subunit 1 (sprot)

A nuclear envelope phosphatase-regulatory subunit 1 that is encoded in the genome of human.


PLPL5_HUMAN Patatin-like phospholipase domain-containing protein 5 (sprot)

A patatin-like phospholipase domain-containing protein 5 that is encoded in the genome of human.


GRP1_MOUSE RAS guanyl-releasing protein 1 (sprot)

A RAS guanyl-releasing protein 1 that is encoded in the genome of mouse.


FGR1A_DANRE Fibroblast growth factor receptor 1-A (sprot)

A protein that is a translation product of the fgfr1a gene in zebrafish.


UGTP_STAHJ Processive diacylglycerol beta-glucosyltransferase (sprot)


KPCG_BOVIN Protein kinase C gamma type (Fragment) (sprot)


PI51B_HUMAN Phosphatidylinositol 4-phosphate 5-kinase type-1 beta (sprot)

A phosphatidylinositol 4-phosphate 5-kinase type-1 beta that is encoded in the genome of human.


Y2167_STAHJ Putative lipid kinase SH2167 (sprot)


Diacylglycerol

A glyceride that is glycerol in which any two of the hydroxy groups have been acylated. In the structure shown, two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.


VSPJF_PROJR Beta-fibrinogenase jerdofibrase (Fragment) (sprot)


SDRG_STAEP Serine-aspartate repeat-containing protein G (sprot)


VSP2_PROEL Thrombin-like enzyme elegaxobin-2 (sprot)


VSP1_PROEL Thrombin-like enzyme elegaxobin-1 (sprot)


FMAD_ASPFU O-methyltransferase af390-400 (sprot)


FMAH_ASPFU Stereoselective keto-reductase af490 (sprot)


FMAC_ASPFU Polyketide transferase af380 (sprot)


FMAA_ASPFU Fumagillin beta-trans-bergamotene synthase af520 (sprot)


FUMR_ASPFU C6 finger transcription factor fumR (sprot)


FMAB_ASPFU Fumagillin dodecapentaenoate synthase af370 (sprot)


FMAG_ASPFU Multifunctional cytochrome P450 monooxygenase af510 (sprot)


VEA_ASPFU Developmental and secondary metabolism regulator veA (sprot)


LYPA2_MOUSE Acyl-protein thioesterase 2 (sprot)

An acyl-protein thioesterase 2 that is encoded in the genome of mouse.


LANC1_HUMAN Glutathione S-transferase LANCL1 (sprot)

A glutathione S-transferase LANCL1 that is encoded in the genome of human.


LANC1_MOUSE Glutathione S-transferase LANCL1 (sprot)

A glutathione S-transferase LANCL1 that is encoded in the genome of mouse.