transcription factor AP-1 complex

A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.


skin mucous gland

biolink:GrossAnatomicalStructure biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A mucous gland that is part of the skin.


webbed manus

A manus that has_part a webbed interdigital region.


right lung accessory lobe segmental bronchus

A segmental bronchus that is part of a right lung accessory lobe.


scent gland

Scent glands are exocrine glands found in most mammals. They produce semi-viscous secretions which contain pheromones and other semiochemical compounds. These odor-messengers indicate information such as status, territory marking, mood, and sexual power. The odor may be subliminal-not consciously detectable. Though it is not their primary function, the salivary glands may also function as scent glands in some animals.


hepatic sinusoid of right of lobe of liver

A hepatic sinusoid that is part of a right lobe of liver.


Myc-Max complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max.


thyroid vein

A vein that drains a thyroid gland.


bI4 intron splicing complex

A protein complex required for the splicing of intron 4 of the cytochrome b (COB) gene. In S. cerevisiae, the complex contains the maturase bI4 (which derives from one of the products of the splicing), Leucyl-tRNA synthetase NAM2 and the intron 4 of the cytochrome b pre-mRNA. The two proteins stimulate the ribozyme activity of the pre-mRNA which autoctalyse a group I intron splicing.


hindlimb digital vein

A digital vein that is part of a hindlimb [Automatically generated definition].


tRNA (m2G10) methyltransferase complex

A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.


nuclear membrane complex Bqt3-Bqt4

A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.


gastrointestinal peritoneum

Peritoneum that surrounds the stomach and intestines.


embryonic cloacal epithelium

An epithelium that is part of a embryonic cloaca.


somite 22

Undifferentiated mesodermal component of early tail segment 22 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


SUMO ligase complex

A protein ligase complex that enables protein sumoylation. Consists of a SUMO-protein transferase and other proteins that may confer substrate specificity of the complex.


plasma membrane-derived thylakoid photosystem II

A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.


carotid sinus

A localized dilation of the internal carotid artery at its origin, the common carotid artery bifurcation.


collagen type XX trimer

A collagen homotrimer of alpha1(XX) chains.


trachea basement membrane

biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A basement membrane that is part of a trachea.


pyloric gastric gland

The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP].


starch utilization system complex

A bacterial cell envelope-associated multiprotein system, which binds and degrades starch.


internal jugular vein

One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted].


ascending cervical artery

The ascending cervical artery is a small branch which arises from the inferior thyroid artery as that vessel is passing behind the carotid sheath; it runs up on the anterior tubercles of the transverse processes of the cervical vertebrC& in the interval between the Scalenus anterior and Longus capitis. To the muscles of the neck it gives twigs which anastomose with branches of the vertebral, and it sends one or two spinal branches into the vertebral canal through the intervertebral foramina to be distributed to the medulla spinalis and its membranes, and to the bodies of the vertebrC&, in the same manner as the spinal branches from the vertebral. It anastomoses with the ascending pharyngeal and occipital arteries.


A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).


superficial external pudendal artery

An artery that arises from the medial side of the femoral artery, close to the superficial epigastric artery and superficial iliac circumflex artery.


Ost-alpha/Ost-beta complex

A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity.


TRAPPI protein complex

A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the core subunits of all TRAPP complexes in yeast.


left gastric lymph node

Gastric lymph node located along the lesser curvature of stomach.


homodimeric serine palmitoyltransferase complex

A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine.


pericardio-peritoneal canal mesothelium

A mesothelium that is part of a pericardio-peritoneal canal.


cutaneus magnus

Anterior part of the lateral vein.


reticular tissue

Loose connective tissue which consists of an irregular network of cells and reticular fibers and is spatially associated with myeloid and lymphoid cells. Examples: stroma of bone marrow, stroma of spleen, stroma of lymph node.[FMA].


IgD B cell receptor complex

An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


proton-transporting ATP synthase, central stalk

One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis.


quadrate lobe hepatic sinusoid

A hepatic sinusoid that is part of a quadrate lobe of liver.


MBF transcription complex

A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi6p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p.


brain dura mater

The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer.


A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.


A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.


minor sublingual duct

Any of the 8-20 small ducts that open into the mouth on the surface of the sublingual fold.


chloroplast proton-transporting ATP synthase complex

A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation.


deep cervical lymph node

The deep cervical lymph nodes are a group of cervical lymph nodes found near the internal jugular vein. They can be divided into upper and lower groups, or superior and inferior groups. Alternatively, they can be divided into deep anterior cervical lymph nodes and deep lateral cervical lymph nodes. They can also be divided into three groups: superior deep jugular, middle deep jugular, and 'inferior deep jugular'.


middle ear epithelium

An epithelium that is part of a middle ear.


mBAF complex

A muscle cell-specific SWI/SNF-type complex that contains eight to fourteen proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or the SMARCA2/BAF190B/BRM gene, the mammalian ortholog of the Drosophila brm (brahma) gene, or an ortholog of either of these genes, and the muscle-specific product of the DPF3/BAF45C gene or an ortholog thereof.


Rad6-Rad18 complex

A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.


lower leg epithelium

An epithelium that is part of a lower leg [Automatically generated definition].


internal thoracic vein

A vessel that drains the chest wall and breats and arises from the superior epigastric vein, accompanies the internal thoracic artery along its course and terminates in the brachiocephalic vein.


lateral cervical lymph node

A cervical lymph nodes are found in proximity to an internal or external jugular vein.


anal membrane ectodermal component

A unilaminar epithelium that develops_from a ectoderm and is part of a anal region.


lateral malleal ligament

A malleal ligament that extends from the bony margin of the notch of Rivinus to the neck of the malleus.


ModE complex

A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.


articular capsule of hip joint

An articular capsule that is part of the hip joint.


katanin complex

A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).


alpha6-beta4 integrin-Shc-Grb2 complex

A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.


right subcardinal vein

A subcardinal vein that is in_the_right_side_of a multicellular organism.


dorsal artery of penis

The Dorsal Artery of the Penis ascends between the crus penis and the pubic symphysis, and, piercing the inferior fascia of the urogenital diaphragm, passes between the two layers of the suspensory ligament of the penis, and runs forward on the dorsum of the penis to the glans, where it divides into two branches, which supply the glans and prepuce. On the penis, it lies between the dorsal nerve and deep dorsal vein, the former being on its lateral side. It supplies the integument and fibrous sheath of the corpus cavernosum penis, sending branches through the sheath to anastomose with the deep artery of the penis. [WP,unvetted].


myosin IV complex

A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.


chloroplast large ribosomal subunit

The large subunit of a ribosome contained within a chloroplast.


histone H3-K14 acetyltransferase complex

A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3.


INA complex

A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p.


Clr6 histone deacetylase complex I''

A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3.


nucleolar exosome (RNase complex)

A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.


EmrE multidrug transporter complex

A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer.


skin of limb

A zone of skin that is part of a limb [Automatically generated definition].


ligament of hip joint

A skeletal ligament that is part of a hip joint.


pulmonary valve anulus

The fibrous ring of the pulmonary valve that attaches the cusps of pulmonary valve to the wall of right ventricle, and which consists of portions of the fibrous scallops of the anterior, right posterior and left posterior cusps.


plastid-encoded plastid RNA polymerase complex

An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition.


serous gland

A gland in which the principal secretory cells are serous secreting cells.


Ddb1-Ckn1 complex

A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.


syntaxin-6-syntaxin-16-Vti1a complex

A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).


chloroplast proton-transporting ATP synthase complex, catalytic core CF(1)

The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits.


cerebellar central artery

Extend upward from the PCS, branch to provide an arterial feed to the hindbrain, then drain back down into the PHBC Isogai et al. 2001.


laminin-522 complex

A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains.


alpha9-beta1 integrin-ADAM12 complex

A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.


nuclear exosome focus

An nuclear body involved in nuclear mRNA surveilllance. Contains at least Mmi1, or an ortholog of it, and the nuclear exosome.


inferior phrenic vein

The Inferior Phrenic Veins drain the diaphragm and follow the course of the inferior phrenic arteries; the right ends in the inferior vena cava; the left is often represented by two branches, one of which ends in the left renal or suprarenal vein, while the other passes in front of the esophageal hiatus in the diaphragm and opens into the inferior vena cava. [WP,unvetted].


SCF-Ucc1 ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae.


deep anterior cervical lymph node

The deep anterior cervical lymph nodes are found near the middle cricothyroid ligament and the trachea.


mixed stratified cuboidal and columnar epithelium

Multilaminar epithelium, which consists of more than one layer of cuboidal and columnar cells, only one layer of which is in contact with a basement membrane. Examples: epithelium of wall of pancreatic duct, epithelium of wall of duct of salivary gland.


efferent spiracular artery

A section of a pharyngeal arch artery that drains the spiracle.


dorsal vein of penis

One of the superficial dorsal vein of the penis or the deep dorsal vein of the penis.


testicular vein

A vein that carries deoxygenated blood from a single male gonad. It is the male equivalent of the ovarian vein, and is the venous counterpart of the testicular artery. It is a paired vein, with one supplying each testis.


epithelium of mucosa

A layer of epithelial cells on the surface of the mucosa.


tunica intima of artery

A tunica intima that is part of a artery.


kidney blood vessel

A blood vessel that is part of a kidney [Automatically generated definition].


arteriole of colon

An arteriole located in the colon.


photosystem I

A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation).


polyphosphate kinase complex

A protein complex that possesses polyphosphate kinase activity.


supraorbital vein

The supraorbital vein begins on the forehead where it communicates with the frontal branch of the superficial temporal vein. It runs downward superficial to the Frontalis muscle, and joins the frontal vein at the medial angle of the orbit to form the angular vein. Previous to its junction with the frontal vein, it sends through the supraorbital notch into the orbit a branch which communicates with the ophthalmic vein; as this vessel passes through the notch, it receives the frontal diploic vein through a foramen at the bottom of the notch. The areas drained by this vessel are the forehead, eyebrow and upper eyelid. [WP,unvetted].


Grb2-Shc complex

A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.


epithelium of carpal region

An epithelium that is part of a wrist [Automatically generated definition].


nuchal ligament

A fibrous membrane, which, in the neck, represents the supraspinal ligaments of the upper vertebrae.


mucous gland

A gland in which the principal secretory cells are mucus secreting cells.


ryanodine receptor complex

A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.


A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.


cervical fascia

Any fascia tissue that is part of the neck region.


epithelium of superior semicircular canal

An epithelium that is part of an anterior semicircular canal [Automatically generated definition].


myosin XII complex

A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.


principal vein of forelimb

A prinicipal vein of limb that is part of a forelimb.


cervical loop

The cervical loop is the location on an enamel organ in a developing tooth where the outer enamel epithelium and the inner enamel epithelium join. The cervical loop is a histologic term indicating a specific epithelial structure at the apical side of the tooth germ, consisting of loosely aggregated stellate reticulum in the center surrounded by stratum intermedium. These tissues are enveloped by a basal layer of epithelium known on the outside of the tooth as outer enamel epithelium and on the inside as inner enamel epithelium. During root formation the inner layers of epithelium disappear and only the basal layers are left creating Hertwig's Epithelial Root Sheath (HERS). At this point it is usually referred to as HERS instead of the cervical loop to indicate the structural difference[WP].


deep temporal artery

The deep temporal arteries, two in number, anterior and posterior, ascend between the Temporalis and the pericranium. They supply the muscle, and anastomose with the middle temporal artery. The anterior communicates with the lacrimal artery by means of small branches which perforate the zygomatic bone and great wing of the sphenoid.


endosomal scaffold complex

A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling.


mitochondrial electron transfer flavoprotein complex

A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.


peptidase complex

A protein complex which is capable of peptidase activity.


enzyme activator complex

A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active.


anterior tibial vein

A vein of the lower limb that carries blood from the anterior compartment of the leg to the popliteal vein which is forms when it joins with the posterior tibial vein. Like most deep veins, the anterior tibial vein is accompanied by an artery of the same name, the anterior tibial artery, along its course. [WP,unvetted].


mitochondrial ATP-gated potassium channel complex

A protein-containing complex that is capable of the ATP-dependent diffusion of a potassium ion across the mitochondrial inner membrane.


A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.


Tic complex

The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.


aorta

The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation.


heart rudiment

A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.


dartos muscle

The dartos fascia is a fat-free layer of smooth muscular fiber outside the external spermatic fascia but below the skin. It is a continuation of Scarpa's Fascia which is a membranous layer of the subcutaneous tissue in the abdominal wall.


left internal carotid artery

An internal carotid artery that branching_part_of a left common carotid artery plus branches.


thoracodorsal vein

Companion vein of the thoracodorsal artery, draining the apical part of the latissimus dorsi and merging with the circumflex scapular vein to form a subscapular vein.


A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.


epithelium of knee

An epithelium that is part of a knee [Automatically generated definition].


duodeno-pancreatic artery

Major branch which supplies blood to pancreas and duodenum.


respiratory system arterial blood vessel

An arterial blood vessel that is part of a respiratory system [Automatically generated definition].


corneal blood vessel

A blood vessel that is part of a cornea [Automatically generated definition].


endoplasmic reticulum protein-containing complex

A protein complex that is part of an endoplasmic reticulum.


glomerular epithelium

The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros.


plastid mRNA editing complex

An mRNA editing complex found in a plastid.


SRF-myogenin-E12 complex

A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.


tumor necrosis factor receptor superfamily complex

A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.


hair follicle isthmus

The middle part of the hair follicle that extends from the sebaceous duct to the bulge.


non-keratinized epithelium of tongue

A non-keratinized stratified squamous epithelium that is part of a tongue.


spleen trabecular vein

One of the veins that feed the splenic vein.


visceral fascia

Fascia that suspends a visceral organ.


MsbA transporter complex

An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD).


diencephalon dura mater

A dura mater that is part of a diencephalon [Automatically generated definition].


transcription factor TFIIK complex

A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin28p/CDK7.


alphaIIb-beta3 integrin-CIB complex

A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.


mesencephalic artery

The major artery of the midbrain, which crosses the midbrain medially to meet its partner the mesencephalic vein.


spinal cord neural plate

A neural plate that develops_from a future spinal cord.


eponychium

Thickened layer of skin surrounding fingernails and toenails. Beneath the cuticle is a thin layer of a membrane known as the pterygium. The function is to protect the area between the nail and epidermis from exposure to harmful bacteria. The vascularization pattern is similar to that of perionychium. The eponychium is the end of the proximal fold that folds back upon itself to shed an epidermal layer of skin onto the newly formed nail plate. This layer of non-living, almost invisible skin is the cuticle that 'rides out' on the surface of the nail plate. Together, the eponychium and the cuticle form a protective seal. The cuticle on the nail plate is dead cells and is often removed during manicure, but the eponychium is living cells and should not be touched.[6] The perionyx is the projecting edge of the eponychium covering the proximal strip of the lunula[WP].


collagen type XII trimer

A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.


sublumbar lymph node

A lymph node with a lymph center located within the caudal abdomen and pelvis, on the ventral side of the lumbar region. Includes the medial iliac, internal iliac (previously termed hypogastric) and sacral lymph nodes.


median sacral vein

The median sacral vein (or middle sacral veins) accompany the corresponding artery along the front of the sacrum, and join to form a single vein, which ends in the left common iliac vein; sometimes in the angle of junction of the two iliac veins.


ferredoxin hydrogenase complex

An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.


pre-replicative complex

A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.


plasma membrane proton-transporting ATP synthase complex, catalytic core F(1)

The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species.


left subcardinal vein

A subcardinal vein that is in_the_left_side_of a multicellular organism.


posterior cruciate ligament of knee joint

A fibrous band extending between the posterior intercondyloid fossa of the tibia and the anterior lateral region of the medial condyle on the femur to prevent the knee from moving posteriorly.


rixosome complex

A conserved RNA endonuclease complex required for spreading and epigenetic inheritance of heterochromatin. The rixosome contains six unique subunits: three structural subunits (Crb3, Rix1, and Ipi1) which form the core of the complex, and three catalytic subunits (the endonuclease Las1, the polynucleotide kinase Grc3, and the AAA-type ATPase Mdn1), which are involved in the processing of ribosomal RNA precursors. All subunits are essential for viability and are conserved from yeast to mammals, including humans.


pericardiacophrenic vein

Vena comitans of the pericardiacophrenic arteries.


vasa recta

In the blood supply of the kidney, the vasa recta renis (or straight arteries of kidney, or straight arterioles of kidney) form a series of straight capillaries in the medulla. They lie parallel to the loop of Henle. These vessels branch off the efferent arterioles of juxtamedullary nephrons (those nephrons closest to the medulla), enter the medulla, and surround the loop of Henle.


alpha9-beta1 integrin-ADAM9 complex

A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.


Grb2-Sos complex

A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.


early distal convoluted tubule

The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive[GO].


distal convoluted tubule macula densa

A macula densa that is part of a distal convoluted tubule [Automatically generated definition].


pyloric region epithelium

An epithelium that is part of a pylorus.


aspartate carbamoyltransferase complex

A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides.


arm blood vessel

A blood vessel that is part of an arm [Automatically generated definition].


parotid gland intercalated duct

Any of the small intralobular tubular canal that leads directly from the serous acinus of the parotid gland to a striated (secretory) duct; in mouse, the intercalated ducts are short and narrow and are lined by low cuboidal epithelial cells with large central nuclei; they secrete bicarbonate ion into and absorb chloride ion from the acinar product.


synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex

A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).


UBR1-RAD6 ubiquitin ligase complex

A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes.


ileocolic vein

The ileocolic vein is a vein which drains the ileum, colon, and cecum. [WP,unvetted].


Tpg-containing telomere binding complex

A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species.


DNA methyltransferase complex

A protein complex that possesses DNA methyltransferase activity.


genital artery

One of the laterally paired arteries that supply the gonads.


eye epithelium

An epithelium that is part of a camera-type eye.


superficial vein

Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers.


MUB1-RAD6-UBR2 ubiquitin ligase complex

A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.


internal iliac vein

A vein that begins near the upper part of the greater sciatic foramen, passes upward behind and slightly medial to the hypogastric artery and, at the brim of the pelvis, joins with the external iliac to form the common iliac vein. [WP,unvetted].


midbrain neural plate

A neural plate that develops_from a presumptive midbrain.


PSII associated light-harvesting complex II

Protein-pigment complex associated with photosystem II.


nucleoplasmic THO complex

The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits.


DnaA-DiaA complex

A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA.


columnar epithelium

An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified].


Sertoli cell barrier

The blood-testis barrier (abbreviated as BTB) is a physical barrier between the blood vessels and the seminiferous tubules of the animal testes. The barrier is formed by tight connections between the Sertoli cells, which are sustentacular cells (supporting cells) of the seminiferous tubules, and nourish the spermatogonia. The barrier prevents passage of cytotoxic agents (bodies or substances that are toxic to cells) into the seminiferous tubules.


dorsal longitudinal vein

Vessel that connects to the primitive hindbrain channel and the basilar artery at the caudal end of the medulla oblongata. Isogai et al. 2001.


interleukin-2 receptor complex

A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits.


left renal vein

A renal vein that drains the left kidney.


photosystem II

A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center.


plasma membrane respiratory chain complex I

A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.


umbilical vein endothelium

An endothelium that is part of a umbilical vein.


foregut duodenum mesentery

A mesentery of duodenum that is part of a foregut.


isocitrate dehydrogenase complex (NAD+)

Complex that possesses isocitrate dehydrogenase (NAD+) activity.


capillary of colon

A capillary that is part of the colon.


Lsm-containing SMN-Sm protein complex

An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.


deep middle cerebral vein

The blood vessel that receives deoxygenated blood from the insula and gyri and drains into the basal vein of Rosenthal deep in the lateral sulcus.


right colic artery

The right colic artery may arise directly from the superior mesenteric artery (SMA) but often arises from a common trunk with the ileocolic artery or middle colic artery. It supplies the ascending colon.


myosin VI complex

A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.


Kir2 inward rectifier potassium channel complex

A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells.


core TFIIH complex portion of NEF3 complex

The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3).


crypt of Henle

Crypts of Henle are microscopic pockets found in scattered sections of the conjunctiva around the eyeball. They are responsible for secreting mucin, a proteinous substance that makes up the inner layer of tears. It coats the cornea to provide a hydrophilic layer that allows for even distribution of the tear film. The layer of mucin allows tears to glide evenly across the eye's surface[WP].


U11 snRNP

A ribonucleoprotein complex that contains small nuclear RNA U11, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U11 snRNP, most of which remain associated with the U11 snRNA both while the U11 snRNP is free or assembled into a series of spliceosomal complexes.


atrioventricular canal endocardium

Endocardium that is part of the atrioventricular canal[ZFA,vetted].


leg blood vessel

A blood vessel that is part of a leg [Automatically generated definition].


arm skin

A zone of skin that is part of an arm [Automatically generated definition].


Sm-like protein family complex

A protein complex containing members of the Like-Sm family of proteins, which includes both the Sm proteins and the Lsm proteins, and which generally form hexameric or heptameric ring structures which bind to RNA. While some of these ring complexes may form independently of RNA, many only form in association with their target RNA. In addition to Lsm-family proteins, many of these complexes contain additional protein members. Members of this family of complexes include the snRNPs which comprise the majority of the spliceosome. Others are involved in the 5' to 3' degradation pathways of mRNAs in the cytoplasm and of unspliced transcripts in the nucleus, as well as other diverse roles.


meninx of telencephalon

A meninx that is part of a telencephalon [Automatically generated definition].


manual digit 1 epithelium

An epithelium that is part of a manual digit 1.


stellate reticulum

The stellate reticulum is a group of cells located in the center of the enamel organ of a developing tooth. These cells are star shaped and synthesize glycosaminoglycans. As glycosamingoglycans are produced, water is drawn in between the cells and stretch them apart. As they are moved further away from one another, the stellate reticulum maintain contact with one another through desmosomes, resulting in their unique appearance. stellate reticulum is lost after the first layer of dentin is laid down. this brings cells in inner enamel epithelium closer to blood vessels at the periphery[WP].


extraembryonic portion of umbilical artery


glycine reductase complex

Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.


nuclear pre-replicative complex

A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.


recurrent branch afferent branchial artery

The anterioventral proceeding branch of the afferent branchial artery. Isogai et al. 2001.


intersomitic vessel

One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites.


iNOS-S100A8/A9 complex

A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine.


contractile vacuole pore

Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.


midgut duodenum mesentery

A mesentery of duodenum that is part of a midgut.


suprascapular vein

The suprascapular vein is a vein running above the scapula. It empties into the external jugular vein.


superficial epigastric artery

An artery that arises from the femoral artery and supplies the abdominal wall. It distributes branches to the superficial subinguinal lymph glands, the superficial fascia, and the integument; it anastomoses with branches of the inferior epigastric, and with its fellow of the opposite side.


A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


RNA polymerase IV transcription regulator complex

A transcription factor complex that acts at a regulatory region of a gene transcribed by RNA polymerase IV.


submandibular gland primordium epithelium

An epithelium that is part of a submandibular gland primordium.


HDA1 complex

A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.


superior left gastric lymph node

Left gastric lymph node located along the left gastric artery.


tail blood vessel

A blood vessel that is part of a tail [Automatically generated definition].


RNA polymerase I core factor complex

A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.


succinate-CoA ligase complex

A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP.


principal gastric gland

One of the gastric glands that secretes the hydrochloric acid of the gastric juice[Stedman's].


somite 21

Undifferentiated mesodermal component of early tail 21 segment or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


Weber's gland

One of the lingual glands located on the lateral margins of the tongue, at the level of the foliate papillae and in the root of the tongue behind the circumvallate papillae.


Krause's gland

Small, mucous accessory lacrimal glands that are found underneath the eyelid where the upper and lower conjuctivae meet. Their ducts unite into a rather long sinus which open into the fornix conjunctiva. There are approximately forty Krause glands in the region of the upper eyelid, and around 6 to 8 in the region of the lower lid. The function of these glands are to produce tears which are secreted onto the surface of the conjuctiva.


serosa of small intestine

A serous membrane that is part of a small intestine [Automatically generated definition].


GBAF complex

A SWI/SNF subcomplex that incorporates two mutually exclusive paralogs, GLTSCR1 (glioma tumor suppressor candidate region gene 1) or GLTSCR1L (GLTSCR1-like), BRD9 (bromodomain-containing 9) and the BAF subunits BAF155, BAF60, SS18, BAF53a, and BRG1/BRM.


CENP-A containing chromatin

The specialized chromatin located in the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.


vein of lip

A vein that drains a lip.


tendon of biceps brachii

A tendon that attaches_to a biceps brachii.


alpha6-beta4 integrin-Fyn complex

A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.


developing neuroepithelium

An embryonic or larval epithelium that is committed to form part of the nervous system.


midbrain arachnoid mater

An arachnoid mater that is part of a midbrain [Automatically generated definition].


forebrain meninges

A meninx that is part of a forebrain [Automatically generated definition].


white pulp of spleen

The parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies.


brachial vein

A vein that accompanies the brachial artery between the shoulder and the elbow.


somite 16

Undifferentiated mesodermal component of early trunk segment 16 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


limb blood vessel

A blood vessel that is part of a limb [Automatically generated definition].


right gastroepiploic artery

Artery that runs from right to left along the greater curvature of the stomach, between the layers of the greater omentum, anastomosing with the left gastroepiploic branch of the splenic artery.


bronchial vein

The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted].


left posteriolateral flagellum

A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body.


TFIIIC-TOP1-SUB1 complex

A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.


epithelium of rectum

An epithelium that is part of a rectum [Automatically generated definition].


continuous capillary

Capillary that has endothelial cells that provide an uninterrupted lining, and only allow small molecules, like water and ions to diffuse through tight junctions which leave gaps of unjoined membrane which are called intercellular clefts.


S100A9 complex

A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility.


multimerin complex

Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures.


thymoid

A thymus-like lympho-epithelial structures, in the tips of the gill filaments and the neighbouring secondary lamellae (both within the gill basket) of lamprey larvae.


mitochondrial proton-transporting ATP synthase, catalytic core

The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.


middle vesical artery

The middle vesical artery, usually a branch of the superior vesical artery, is distributed to the fundus of the bladder and the seminal vesicles.


main bronchus blood vessel

A blood vessel that is part of a main bronchus [Automatically generated definition].


pentameric IgM immunoglobulin complex

A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.


I(KACh) inward rectifier potassium channel complex

An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G protein-coupled receptor signaling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.


nucleotide-excision repair factor 4 complex

One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p.


PUMA-BCL-xl complex

A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.


brain meninx

A meninx that is part of a brain [Automatically generated definition].


Bam protein complex

Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.


principal vein of hindlimb

A prinicipal vein of limb that is part of a hindlimb.


primary head sinus

Main route for venous drainage of the anterior and mid cerebral veins as well as portions of the primordial hindbrain channel. Isogai et al. 2001.


serotonin receptor complex

A protein complex that is capable of serotonin receptor activity.


myosin VII complex

A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.


back blood vessel

A blood vessel that is part of a back [Automatically generated definition].


toxin-antitoxin complex

A bacterial protein complex that neutralises its own toxin by complexing the toxin with the antitoxin. The antitoxin can be either a protein or an RNA. The neutralising toxin-antitoxin complex also acts as a transcriptional repressor of the toxin-antitoxin operon.


cytosolic pyruvate dehydrogenase complex

Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.


mitochondrial respiratory chain complex IV pre-assembly complex

A protein complex that contributes to and regulates mitochondrial respiratory chain complex IV (COX) formation. It acts by regulating mitochondrial COX1 translation and by promoting the assembly of COX components.


vitelline artery

The paired arteries that carry blood to the yolk sac from the dorsal aorta.


high endothelial venule of appendix

A high endothelial venule that is located in the vermiform appendix.


dorsal digital artery of pes

The dorsal digital arteries of foot are small arteries which supply the toes.


hemipenis keratinized epithelium

A keratinized stratified squamous epithelium that is part of a hemipenis.


spinal vein

A vein that is part of a vertebral column.


distal sesamoid impar ligament

A short wide fibrous structure that attaches proximally to the navicular (distal sesamoid) and distally to the palmar margin of the flexor surface of the distal phalanx.


transcription factor TFIIIC1 complex

A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.


actomyosin, myosin complex part

The myosin part of any complex of actin, myosin, and accessory proteins.


third ventricle ependyma

An ependyma that is part of a third ventricle [Automatically generated definition].


thymus

Anatomical structure of largely lymphoid tissue that functions in cell-mediated immunity by being the site where T cells develop.


U4atac snRNP

A ribonucleoprotein complex that contains small nuclear RNA U4atac, a heptameric ring of Sm proteins, as well as several proteins that are unique to the U4atac snRNP, most of which remain associated with the U4atac snRNA both while the U4atac snRNP is free or assembled into the U4atac/U6atac complex or into a series of spliceosomal complexes.


collagen type XXVIII trimer

A collagen homotrimer of alpha1(XXVIII) chains.


heart endothelium

An endothelium that is part of a heart [Automatically generated definition].


skin of head

A zone of skin that is part of a head [Automatically generated definition].


mesentery of urinary system

A mesentery that is part of a urinary system [Automatically generated definition].


median lingual swelling epithelium

An epithelium that is part of a median lingual swelling.


alpha5-beta1 integrin-tissue transglutaminase complex

A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.


pyruvate dehydrogenase (lipoamide) phosphatase complex

A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.


third ventricle choroid plexus epithelium

A choroid plexus epithelium that is part of a third ventricle [Automatically generated definition].


collagen type XIV trimer

A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.


chromatin lock complex

A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping.


manus blood vessel

A blood vessel that is part of a manus [Automatically generated definition].


anterior cervical lymph node

The anterior cervical lymph nodes are a group of nodes found on the anterior part of the neck.


cervical mucosa

Lining of the head of the uterus (cervix); contains large branched glands; does not undergo sloughing.


serosa of jejunum

A serous membrane that is part of a jejunum [Automatically generated definition].


sodium ion-transporting V-type ATPase complex

A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis.


alpha9-beta1 integrin-ADAM8 complex

A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.


Delta1 complex

A protein complex that consists of homodimer of the Notch ligand Delta1.


catalytic complex

A protein complex which is capable of catalytic activity.


ERBB4:ERBB2 complex

A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.


cargo receptor complex

Any protein complex that is part of a membrane and which functions as a cargo receptor.


cytosolic creatine kinase complex

A dimeric protein complex having creatine kinase activity.


regenerating fin/limb

Fin or limb undergoing the process of regeneration.


gland of nasal mucosa

The nasal glands are the seromucous glands in the respiratory region of the nasal mucous membrane. The three major types of nasal glands are anterior serous glands, seromucous glands, and Bowman glands.


An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate.


transcription preinitiation complex

A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.


lymph node of upper limb

A lymph node that is part of a forelimb.


axilla skin

A zone of skin that is part of a axilla.


exocrine pancreas epithelium

Epithelium lining the exocrine pancreas.


STING complex

A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response.


IgD immunoglobulin complex

A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


respiratory system epithelium

An epithelium that is part of a respiratory system [Automatically generated definition].


SCF-Pof5 ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae).


lymph node of head

A lymph node that is part of a head.


integrin alphaD-beta2 complex

An integrin complex that comprises one alphaD subunit and one beta2 subunit.


interleukin-13 receptor complex

A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain.


lacrimal gland bud

The single bud-like invagination of the conjunctival fornix epithelium at the temporal aspect of the eye that signals lacrimal gland formation (Int Rev Cytol. 1996;168:1-80. Cell biology of the harderian gland).


barnacle cement gland

Typical barnacles, common name of the sedentary crustacean marine animals constituting the subclass Cirripedia, attach to the substrate by means of an exceedingly adhesive cement, produced by a cement gland, and secrete a shell, or carapace, of calcareous (limestone) plates, around themselves.


internal mammary vein

One of two veins running parallel to their corresponding internal mammary arteries that unite forming one vessel. These veins drain the chest wall into the innominate vein.


RNA polymerase IV transcription repressor complex

A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter.


abdominal segment blood vessel

A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition].


myosin XVII complex

A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.


A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.


Rpd3L-Expanded complex

A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.


Kv4.2-KChIP4 channel complex

A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.


trunk blood vessel

A blood vessel that is part of a trunk [Automatically generated definition].


mitral valve anulus

The fibrous ring of the mitral valve that attaches the cusps of mitral valve to the heart, and which consists of portions of the fibrous scallops of the anterior and posterior cusps.


late distal convoluted tubule

The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO].


anterior mesencephalic central artery

Arteries that irrigate rostral regions of the midbrain. They extend between the Basial communicating artery to the anterior cerebral vein. Isogai et al. 2001.


left colic artery

The first branch of the inferior mesenteric artery (IMA) is the left colic artery. The left colic artery supplies blood flow to the distal third of the transverse colon and the entirety of the descending colon. Once diverging from the IMA, the left colic artery runs anterior to the left ureter, left internal spermatic vessels (males), and psoas major before branching into its ascending and descending segments.


alpha4-beta1 integrin-CD82 complex

A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.


forebrain arachnoid mater

An arachnoid mater that is part of a forebrain [Automatically generated definition].


epithelium of male gonad

An epithelium surrounding a testis.


A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin.


caecum epithelium

An epithelium that is part of a caecum.


sigma factor antagonist complex

A protein complex which is capable of sigma factor antagonist activity.


female preputial gland

The paired, lobulated, modified sebaceous glands located on the side of the clitoris in female rodents; in contrast to the preputial glands in male rodents, clitoral glands are a minor source of olfactory stimuli contributing to sexual attractivity; unlike other sebaceous glands, they undergo progressive atrophy of the glandular portion with marked ductal ectasia as rodents age.


liver blood vessel

A blood vessel that is part of a liver.


protein folding chaperone complex

A protein complex required for the non-covalent folding or unfolding, maturation, stabilization or assembly or disassembly of macromolecular structures. Usually active during or immediately after completion of translation. Many chaperone complexes contain heat shock proteins.


respiratory system capillary endothelium

An endothelium of capillary that is part of a respiratory system [Automatically generated definition].


methane monooxygenase complex

A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.


membrane organ

Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA].


canal of Schlemm

The vascular structure encircling the anterior chamber of the eye, through which the aqueous humor is returned to the blood circulation.


umbilical blood vessel

One of the three blood vessels, usually one large umbilical vein and two small umbilical arteries, buried within Wharton's jelly, that transport blood to and from the placenta, where exchange between the mother and fetus takes place; the umbilical vein carries oxygenated, nutrient-rich blood from the placenta to the fetus, and the umbilical arteries carry deoxygenated, nutrient-depleted blood from the fetus to the placenta.


ERBB3:ERBB2 complex

A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3.


small cardiac vein

A vein running parallel to the right coronary artery in the coronary sulcus that drains into the right extremity of the coronary sinus.


areolar sweat gland

Any sweat gland that is part of an areola.


forelimb blood vessel

A blood vessel that is part of a forelimb [Automatically generated definition].


IgE immunoglobulin complex, circulating

A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


anterior longitudinal ligament

A ligament running the length of the anterior surface of the spinal column and thereby interconnects all the vertebral bodies.


parasternal lymph node

Any of the lymph nodes of the breast located under the ribcage, near the sternum.


auxin efflux carrier complex

The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell.


plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex

A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.


medial circumflex femoral artery

The medial circumflex femoral artery (internal circumflex artery, medial femoral circumflex artery) is an artery in the upper thigh that helps supply blood to the neck of the femur. [WP,unvetted].


monomeric IgA immunoglobulin complex

A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


internal iliac lymph node

The internal iliac lymph nodes (or hypogastric) surround the internal iliac artery and its branches (the hypogastric vessels), and receive the lymphatics corresponding to the distribution of the branches of it, i. e. , they receive lymphatics from all the pelvic viscera, from the deeper parts of the perineum, including the membranous and cavernous portions of the urethra, and from the buttock and back of the thigh. It does not receive lymph from the ovary, testis, or superior half of the rectum; the gonads drain to the paraaortic lymph nodes, while the superior half of the rectum drains to the pararectal lymph nodes.


pseudobranchial artery

A vascular loop attached to the efferent part of the mandibular arch that forms at 3.5 dpf. Isogai et al. 2001.


endocardium of left ventricle

Any endocardium that is part of the left ventricle of the heart.


aortic sac

The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates.


left gastroepiploic artery

Artery that runs from left to right along the greater curvature of the stomach, between the layers of the greater omentum, and anastomoses with the right gastroepiploic.


alphaPDGFR-SHP-2 complex

A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.


alpha3-beta1 integrin-basigin complex

A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.


mitochondrial iron-sulfur cluster assembly complex

A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine.


mesonephric renal vesicle

The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells[GO].


ophthalmotemporal branch of external ophthalmic artery


cricoid cartilage

A cartilaginous ring that provides support for the arytenoid cartilages and forms the caudal part of the larynx.


extraembryonic epithelium

An epithelium that is part of a extraembryonic structure.


alpha6-beta4 integrin-laminin 5 complex

A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.


eye primordium

Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles.


SLIK (SAGA-like) complex

A SAGA-type histone acetyltransferase complex that contains a smaller form of Spt7 (lacking the SPT8 binding region) than the fungal SAGA complex, and consequently lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction.


abdomen blood vessel

A blood vessel that is part of an abdomen [Automatically generated definition].


trophectoderm

Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition.


helicine branch of uterine artery

The helicine branches of uterine artery (or helicine arterioles, or spiral arteries) are small arteries which temporarily supply the endometrium of the uterus during the luteal phase of the menstrual cycle. In histology, identifying the presence of these arteries is one of the most useful techniques in identifying the phase of the cycle.


fatty-acyl-CoA synthase complex

A protein complex that possesses fatty-acyl-CoA synthase activity.


anterior limiting lamina of cornea

A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane.


head or neck skin

A zone of skin that is part of a craniocervical region.


meninx of diencephalon

A meninx that is part of a diencephalon [Automatically generated definition].


common iliac lymph node

The external iliac lymph nodes, from eight to ten in number, lie along the external iliac vessels. They are arranged in three groups, one on the lateral, another on the medial, and a third on the anterior aspect of the vessels; the third group is, however, sometimes absent. Their principal afferents are derived from the inguinal lymph nodes, the deep lymphatics of the abdominal wall below the umbilicus and of the adductor region of the thigh, and the lymphatics from the glans penis vel clitoridis, the membranous urethra, the prostate, the fundus of the urinary bladder, the cervix uteri, and upper part of the vagina.


glycolate oxidase complex

An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN).


plasma membrane proton-transporting ATP synthase complex

A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species.


prepuce

A retractable double-layered fold of skin and mucous membrane that covers the glans penis or clitoris. Glands may also be present.


serosa of infundibulum of uterine tube

A serous membrane that is part of a uterine tube infundibulum.


umbilical cord blood

Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP].


anterior facial vein

A vein that represents a continuation of the angular vein and lies behind the facial artery.


accessory vertebral vein

A lower continuation of the vertebral vein and vertebral venous plexus that passes through the foramen of the transverse process of the 7th cervical vertebra and empties into the brachiocephalic vein.


A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.


epithelium of intestinal villus

An epithelium that is part of a intestinal villus.


somite 2

Undifferentiated mesodermal component of early trunk segment 2 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


node of ligamentum arteriosum

An inconstant lymph node of the anterior mediastinal group located adjacent to the ligamentum arteriosum.


TRAIL death-inducing signaling complex

A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor.


efflux pump complex

A protein complex that is capable of efflux transmembrane transporter activity.


secondary palatal shelf epithelium

An epithelium that is part of a secondary palatal shelf.


superior thyroid vein

The superior thyroid vein begins in the substance and on the surface of the thyroid gland, by tributaries corresponding with the branches of the superior thyroid artery, and ends in the upper part of the internal jugular vein. It receives the superior laryngeal and cricothyroid veins.


somite boundary epithelium

Epithelium located in the intersomitic region.


left hepatic vein

A hepatic vein that is part of a left lobe of liver.


BIM-BCL-xl complex

A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.


ciliated epithelium

Epithelium bearing vibratile cilia on the free surface.


articular cartilage of joint

A thin layer of cartilage, usually hyaline, on the articular surface of bones in synovial joints.


left testicular vein

A vein that drains the right pampiniform plexus and empties into the inferior vena cava.


alphav-beta3 integrin-collagen alpha3(VI) complex

A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.


naris epithelium

An epithelium that is part of a naris [Automatically generated definition].


plasma membrane respiratory chain complex II

A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species.


primary palate epithelium

An epithelium that is part of a primary palate.


common hepatic lymph node

Hepatic lymph node located along the common hepatic artery.


A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).


brachial lymph node

The lymph nodes located along the brachial vein that receive drainage from most of the free upper limb and send efferent vessels to the central axillary lymph nodes.


alphaV-beta6 integrin-TGFbeta-3 complex

A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).


right umbilical vein

An umbilical vein that is in the right side of a multicellular organism.


pigment epithelium of eye

Epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules.


vacuolar transporter chaperone complex

A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.


small ribosomal subunit processing complex

A small heterodimeric protein complex that is required during early maturation of nascent 40S ribosomal subunits. The complex has endonuclease activity, it interacts with the small ribosomal subunit pre-rRNA and cleave it it to produce the mature 18S (or small ribosomal subunit) rRNA. In S. cerevisiae it is composed of Rcl1p and Bms1p.


nipple sheath

A circular ingrowth of the epidermis around the region of the mammary sprout[GO].


alpha9-beta1 integrin-VEGF-A complex

A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.


hindbrain neural plate

A neural plate that develops_from a presumptive hindbrain.


mitochondrial creatine kinase complex

An octomeric protein complex having creatine kinase activity.


meso-epithelium

Epithelium that derives from the mesoderm. [Automatically generated definition].


serotonin-activated cation-selective channel complex

A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.


ileal artery

The ileal arteries feed oxygenated blood into the ileum, a portion of the small intestine in mammals, reptiles, and birds. They are branches of the superior mesenteric artery.


cranial division of the internal carotid artery


integrin alpha6-beta1 complex

An integrin complex that comprises one alpha6 subunit and one beta1 subunit.


alpha6-beta1 integrin-CD151 complex

A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.


NLRP6 inflammasome complex

An inflammasome complex that consists of NLRP6, PYCARD/ASC and caspase-1 or caspase-4/caspase-11.


heterochromatin domain

A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).


pharyngeal arch artery 5

The vessels formed within the fifth pair of pharyngeal arches in embryogenesis.


thoracic cavity vein

A vein that is part of a thoracic cavity [Automatically generated definition].


cerumen gland

A specialized sudoriferous gland (sweat glands) located subcutaneously in the external auditory canal.


endocardium of ventricle

Endocardium that is part of the cardiac ventricle.


protein complex involved in cell-matrix adhesion

Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion.


skin epithelium

Any region of epithelium that is part of a skin region.


Sec62/Sec63 complex

A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.


suprabranchial fin

Paired fin that is a bilaterally paired anterior outgrowth located high on the side of the animal, not far behind the orbit, with the posterior extremity corresponding with the expected posterior end of the branchial region.


cyanelle ribonuclease P complex

A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.


BCL-2 complex

A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators.


ERBB4-ERBB3 complex

A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission.


pancreatic lymph node

A lymph node that is part of a pancreas [Automatically generated definition].


SCF-Dia2/Pof3 ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).


Cdc50p-Drs2p complex

A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome.


arterial blood

A blood that is part of a artery.


thoracic vein

A vein that is part of a thorax [Automatically generated definition].


costochondral joint

A bars of hyaline cartilage located between the distal part of a rib and a costal cartilage, connecting the ribs to the sternum .


infraclavicular lymph node

A lymph node located in the area below the clavicle.


PSI associated light-harvesting complex I, LHCIa subcomplex

A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.


9+2 non-motile cilium

A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).


plastid acetate CoA-transferase complex

An acetate CoA-transferase complex located in the stroma of a plastid.


A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).


wall of crypt of Lieberkuhn

The lateral parts of an intestinal crypt, continuous distally with the base and proximally with the intestinal villus epithelium.


insulin control element activator complex

Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription.


A protein-containing complex located intracellularly.


epithelium of endolymphatic duct

An epithelium that is part of a endolymphatic duct [Automatically generated definition].


AP-5 adaptor complex

An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo.


H-gal-GP complex

A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.


forelimb digital artery

A digital artery that is part of a forelimb [Automatically generated definition].


Kv4.3-DPP10 channel complex

A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.


chloroplast outer membrane translocon

The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.


GTPase complex

A protein complex which is capable of GTPase activity.


CLOCK-BMAL transcription complex

Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.


cytoplasmic U snRNP body

A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.


buccal gland

Any of the small racemose mucous glands in the mucous membrane lining the cheeks.


molybdenum-iron nitrogenase complex

An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.


afferent spiracular artery

A section of a pharyngeal arch artery that carries blood away from the spiracle.


placenta blood vessel

A blood vessel of the placenta.


Rpd3S complex

A eukaryotically conserved histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).


laminin-6 complex

A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.


IgG immunoglobulin complex

A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


lower eyelid epithelium

An epithelium that is part of a lower eyelid [Automatically generated definition].


cytoplasmic SCF ubiquitin ligase complex

A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).


oral gland

Gland of the epithelium lining the oral cavity. The most common are the salivary glands.


Verson's gland

A gland found in the larvae of lepidoptera. Each gland is made of three cells: the secretory cell, the reservoir cell and the canal cell.


laminin-5B complex

A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains.


forelimb digital vein

A digital vein that is part of a forelimb.


A protein complex that enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).


interleukin-9 receptor complex

A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins.


left supracardinal vein

The left thoracic supracardinal vein loses its connection with the left posterior cardinal veins and left sinus horn and subsequently drains into the right supracardinal system.


mammary fat pad

Encapsulated adipose tissue associated with the mammary gland.


primitive prosencephalic artery

Vessel that branches from cranial division of the internal carotid artery, extending laterally around the rostral end of the head. Isogai et al. 2001.


deep lymph node

A lymph node that is located deeper within the organism, further from the surface.


right extraembryonic umbilical vein

An extraembryonic umbilical vein that is in_the_right_side_of a multicellular organism.


Rpd3L complex

A histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a two copies of catalytic histone deacetylase subunit (S. pombe Clr6/ S. cerevisiae Rpd3p), an Sds-3 family protein (S. pombe /S. cerevisiae Sds3(p) ), two copies of SIN3 family co-repressor (S. pombe Pst1/ S. cerevisiae Sin3p, a WD repeat protein/ histone chaperone (S. pombe Prw1/ S. cerevisiae Ume1p), and a zf- PHD finger ( S. pombe Png2/ S. cerevisiae Pho23p), plus 4 additional subunits, and associated factors.


IgA immunoglobulin complex

A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


perigastric lymph node

Lymph node located in the perigastric region.


tonsil crypt

Tonsils consist of an extensive system of crypts, which result in a large internal surface. The tonsils contain four lymphoid compartments that influence immune functions, namely the reticular crypt epithelium, the extrafollicular area, the mantle zones of lymphoid follicles, and the follicular germinal centers. In human palatine tonsils, the very first part exposed to the outside environment is tonsillar epithelium.


DnaB-DnaC-Rep-PriC complex

A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.


caecum mesentery

A mesentery that is part of a caecum.


postcaval vein

One of three major veins which enter the sinus venosus.


light-activated voltage-gated calcium channel complex

A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus.


middle cardiac vein

The middle cardiac vein commences at the apex of the heart, ascends in the posterior longitudinal sulcus, and ends in the coronary sinus near its right extremity.


prepuce of clitoris

A retractable double-layered fold of skin and mucous membrane that covers the clitoral glans.


medial marginal vein

A continuation of the Dorsal venous arch of the foot and is the origin of the long saphenous vein.


methanophenazine reducing hydrogenase complex

A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides.


venom gland

A gland that secretes venom.


peritoneal cavity mesothelium

A mesothelium that is part of a peritoneal cavity.


lobar bronchus

The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi[GO].


PSII associated light-harvesting complex II, core complex

The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center.


caroticotympanic artery

The caroticotympanic branch (tympanic branch) is small; it enters the tympanic cavity through a minute foramen in the carotid canal, and anastomoses with the anterior tympanic branch of the internal maxillary, and with the stylomastoid artery.


Ecsit-NDUFAF1 complex

Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.


epithelium of laryngopharynx

An epithelium that is part of a hypopharynx.


CUE1-UBC7 ubiquitin-conjugating enzyme complex

A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.


ACF complex

An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.


intercalary heterochromatin

Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes.


ileal vein

The veins that drain blood from the ileum into the superior mesenteric vein.


jugular vein

The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava.


1,3-beta-D-glucan synthase complex

A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.


Kv4.1-DPP10 channel complex

A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.


deep artery of penis

The deep artery of the penis (artery to the corpus cavernosum), one of the terminal branches of the internal pudendal, arises from that vessel while it is situated between the two fascia of the urogenital diaphragm (deep perineal pouch). It pierces the inferior fascia, and, entering the crus penis obliquely, runs forward in the center of the corpus cavernosum penis, to which its branches are distributed.


lacrimal gland

The lacrimal glands are paired almond-shaped glands, located in or near the orbital region, that secrete the aqueous layer of the tear film.[WP].


PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex

A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.


SCF-Met30/Pof1 ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).


procollagen-proline 4-dioxygenase complex, alpha(I) type

A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).


superior parathyroid epithelium

An epithelium that is part of a superior parathyroid gland.


A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.