6-methylsalicylic acid synthase activity

Catalysis of the reaction: acetyl-CoA + 3 H+ + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO2 + 4 CoA + H2O + NADP+.


oogonium development

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes.


phytosteroid catabolic process

The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.


bicoid mRNA localization

Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.


endoplasmic reticulum-organelle membrane tether activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain membrane contact sites and mediate organelle exchange and communication.


Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.


Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.


cadmium ion sensor activity

Binding to and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++).


peptide cross-linking via L-lysinoalanine

The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link.


positive regulation of G1 to G0 transition

Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.


emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity

Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O.


fibronectin fibril organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril.


tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule.


cytochrome P450 dependent beta-amyrin 16beta-hydroxylase activity

Catalysis of the reaction: beta-amyrin + O2 + H+ + NADPH = 16beta-hydroxy-beta-amyrin + H2O + NADP.


nitrate assimilation

The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.


ACG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an ACG codon.


maternal specification of dorsal/ventral axis, oocyte, soma encoded

Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster.


positive regulation of pentasaccharide transport

Any process that activates or increases the frequency, rate or extent of pentasaccharide transport.


seed trichome maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state.


positive regulation of neural crest formation

Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.


establishment of cell polarity involved in growth plate cartilage chondrocyte division

The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte.


pre-tubular aggregate formation

The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).


hydroxycinnamoyltransferase activity

Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.


Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H+.


aldehyde dehydrogenase (NADP+) activity

Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.


Catalysis of the reaction: H2O + an N-acetyl-alpha-D-glucosaminyl-L-serine-[glycoprotein] <=> N-acetyl-alpha-D-glucosaminide + a [protein]-L-serine.


archaeosine synthase activity

Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.


cell-cell adhesion involved in mesendodermal cell migration

The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm.


5'-adenylyl sulfate transmembrane transporter activity

Enables the transfer of 5'-adenylyl sulfate from one side of a membrane to the other.


polycistronic mRNA processing

The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.


Catalysis of the reaction: UDP-alpha-D-glucose + curcumin = curcumin monoglucoside + UDP + H+.


negative regulation of cardiac epithelial to mesenchymal transition

Any process that stops or decreases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


positive regulation of receptor localization to synapse

Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.


macromolecule localization

Any process in which a macromolecule is transported to, or maintained in, a specific location.


forebrain astrocyte fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.


positive regulation of toxin transport

Any process that activates or increases the frequency, rate or extent of toxin transport.


positive regulation of cumulus cell differentiation

Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.


regulation of ribosomal small subunit export from nucleus

Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus.


symbiont defense to host-produced reactive oxygen species

A process in which a symbiont alters or subverts either the host signal transduction pathways leading to the production of reactive oxygen species as part of the host innate immune response.


GCG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GCG codon.


negative regulation of adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway.


ent-kaur-16-en-19-al oxidase activity

Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate.


regulation of Malpighian tubule size

Ensuring that a Malpighian tubule is the correct length and diameter.


alpha-glucan metabolic process

The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.


response to docetaxel trihydrate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.


negative regulation of monocyte activation

Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation.


Catalysis of the reaction: UDP-alpha-D-glucose + N(6)-dimethylallyladenine <=> H+ + 7-(alpha-D-glucosyl)-N(6)-isopentenyladenine + UDP.


translocation of molecules into symbiont

The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


phosphatidylcholine floppase activity

Catalysis of the movement of phosphatidylcholine from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


Group I intron splicing

The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).


globoside biosynthetic process

The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).


ATPase-coupled urea transmembrane transporter activity

Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in).


FAT10 activating enzyme activity

Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.


alkaloid biosynthetic process

The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).


ribonuclease R activity

Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides.


leaf proximal/distal pattern formation

The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.


Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine.


alliin lyase activity

Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.


acyl-lipid omega-(9-4) desaturase activity

Catalysis of the reaction: a (9Z,12Z)-octadecadienoyl-containing glycerolipid + 2 Fe(II)-[cytochrome b5] + 2 H(+) + O2 = a (5Z,9Z,12Z)-octadecatrienoyl-containing glycerolipid + 2 Fe(III)-[cytochrome b5] + 2 H2O. Can also use a substrate with 3 double bonds (a (9Z,12Z,15Z)-octadecatrienoyl-containing glycerolipid) and add a fourth double bond (a (5Z,9Z,12Z,15Z)-octadecatetraenoyl-containing glycerolipid).


oomycete sporangium development

The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated.


biofilm matrix disassembly

A process that results in the disassembly of a biofilm matrix.


Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate.


response to herbivore

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore.


poly(ribitol phosphate) teichoic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid.


Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.


seedling development

The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.


glomerular parietal epithelial cell development

The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


1-18:1-2-16:2-monogalactosyldiacylglycerol desaturase activity (SN2-16:3 forming)

Catalysis of the reaction: 1-18:1-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:1-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate.


tripeptide transmembrane transporter activity

Enables the transfer of a tripeptide, a compound containing three amino acids linked together by peptide bonds, from one side of a membrane to the other.


granulosa cell fate commitment

The cell fate commitment of precursor cells that will become granulosa cells.


NAD+-histone H3S10 serine ADP-ribosyltransferase activity

Catalysis of the transfer of ADP-ribose groups to the serine-10 or an equivalent residue of the N-terminal tail of histone H3.


positive regulation of compound eye pigmentation

Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.


Meynert cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell.


inferior olivary nucleus development

The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


dUDP catabolic process

The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate.


negative regulation of eclosion

Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.


Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.


tRNA-dihydrouridine20 synthase activity

Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) = H+ + a uracil20 in tRNA + NAD(P)H.


epithelial cell proliferation involved in prostatic bud elongation

The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.


regulation of hair follicle placode formation

Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.


GTP:coenzyme F420 guanyltransferase activity

Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate.


Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate.


styrene dioxygenase activity

Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol.


negative regulation of transport across blood-brain barrier

Any process that stops, prevents or reduces the frequency, rate or extent of transport across blood-brain barrier.


Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O2 = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H+.


putrescine oxidase activity

Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2.


Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid.


flight involved in flight behavior

Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.


Catalysis of the reaction: amino acyl-[protein] + NAD+ = H+ + (ADP-D-ribosyl)-amino acyl-[protein] + nicotinamide.


nitrobenzoate nitroreductase activity

Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+.


transport of virus in host, tissue to tissue

The transport of a virus between tissues in a multicellular organism.


regulation of plant-type hypersensitive response

Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.


phenol biosynthetic process

The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.


zinc efflux transmembrane transporter activity

Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.


ribonuclease IX activity

Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.


regulation of metanephric cap mesenchymal cell proliferation

Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.


interleukin-27 production

The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


phosphoribosylglycinamide formyltransferase 2 activity

Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate.


protein phosphopantetheinylation

The modification of a protein amino acid by phosphopantetheinylation.


(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity

Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.


peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine

The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).


disaccharide transmembrane transporter activity

Enables the transfer of disaccharide from one side of a membrane to the other.


peptidyl-tyrosine adenylylation

The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine.


epicardial cell to mesenchymal cell transition

A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium.


regulation of mesonephric glomerular mesangial cell proliferation

Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.


structural constituent of adult chitin-based cuticle

The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster.


regulation of intracellular calcium activated chloride channel activity

Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity.


positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation

Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.


diterpene phytoalexin metabolic process

The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units.


response to bleomycin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.


protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine

Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.


heme O biosynthetic process

The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.


positive regulation of DNA damage checkpoint

Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint.


triglyceride transfer activity

Directly binding to a triglyceride and delivering it either to an acceptor molecule or to a specific location.


Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine.


maturation of 2S rRNA

Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.


osteoclast maturation

A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.


positive regulation of nutrient release by symbiont

Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


anterior lateral line neuromast hair cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.


thiamine diphosphate phosphatase activity

Catalysis of the reaction: thiamine diphosphate + H2O = thiamine monophosphate + phosphate.


embryonic anal fin morphogenesis

The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


cyanidin 7-O-glucoside acyltransferase(acyl-glucose dependent) activity

Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> cyanidin 3-O-glucoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.


shikimate kinase activity

Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H+.


positive regulation of response to cytokinesis checkpoint signaling

Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling.


peroxidase-heme linkage

The covalent linkage of heme to peroxidase.


viral DNA genome packaging, headful

The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).


bixin methyltransferase activity

Catalysis of the reaction: bixin + S-adenosyl-L-methionine <=> bixin dimethyl ester + S-adenosyl-L-homocysteine.


smooth muscle atrophy

A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.


negative regulation of myofibroblast differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation.


cell-abiotic substrate adhesion

The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.


regulation of creatine transmembrane transporter activity

Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity.


Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol.


Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate.


positive regulation of interleukin-1-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway.


receptor-mediated bacteriophage reversible attachment to host cell

Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection.


Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein].


regulation of antigen processing and presentation of polysaccharide antigen via MHC class II

Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.


lariciresinol reductase activity

Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.


negative regulation of pronephric nephron tubule development

Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development.


regulation of mitotic spindle pole body separation

Any process that modulates the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.


symbiont-mediated perturbation of host autophagy

Any process in which a symbiont organism modulates the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


hexose mediated signaling

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals mediated by the detection of hexose.


Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose.


apoptotic process involved in endocardial cushion morphogenesis

Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.


GDP-fucose transmembrane transporter activity

Enables the transfer of a GDP-fucose from one side of a membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.


Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD+ = 4-formylbenzenesulfonate + H+ + NADH.


disruption of cell wall in another organism

The disruption of the cell wall of another organism, leading to damage or temporary subversion of the cell wall.


dibenzothiophene metabolic process

The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion.


positive regulation of uterine smooth muscle relaxation

Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation.


inositol 4-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.


regulation of smooth muscle hypertrophy

Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy.


glyoxylate reductase (NADP+) activity

Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.


response to nitrogen compound

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.


RNA polymerase II C-terminal domain S7 O-GlcNAc transferase activity

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + RNA polymerase II large subunit CTD heptapeptide repeat (YSPTSPS) = UDP + RNA polymerase II large subunit CTD heptapeptide repeat 3-O-(N-acetyl-D-glucosaminyl)-L-serine (position 7).


uracil oxygenase activity

Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate.


phenylacetyl-CoA 1,2-epoxidase activity

Catalysis of the reaction: phenylacetyl-CoA + H+ + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP+.


rhombomere 8 structural organization

The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


scopolin beta-glucosidase activity

Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin.


regulation of podocyte apoptotic process

Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.


3,4-didehydroretinal binding

Binding to 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).


neural crest-derived cardiac fibroblast cell differentiation

The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


histone H3K56me2/H3K56me3 demethylase activity

Catalysis of the removal of a methyl group from a tri or a dimethyl-lysine residue at position 56 of the histone H3 protein.


ABC-type glutathione S-conjugate transporter activity

Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out).


taxusin 2-alpha-hydroxylase activity

Catalysis of the reaction: taxusin + NADPH + O2 + H+ = 2-alpha-hydroxytaxusin + NADP + H2O.


lateral line nerve glial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.


methylputrescine oxidase activity

Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+.


proline dipeptidase activity

Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid.


Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.


positive regulation of pectin catabolic process

Any process that activates or increases the frequency, rate or extent of pectin catabolic process.


negative regulation of long-term synaptic depression

Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.


Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H+ + pyruvate.


F420-0 metabolic process

The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues.


synaptic target attraction

The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.


nitric oxide reductase activity (NAD(P)H-dependent) activity

Catalysis of the reaction: dinitrogen oxide + H2O + NAD(P) = 2 nitric oxide + H+ + NAD(P)H.


racemase and epimerase activity, acting on amino acids and derivatives

Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.


Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA.


dolichol O-acyltransferase activity

Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.


organic substance catabolic process

The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.


dodecyl sulfate metabolic process

The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.


halohydrin hydrogen-halide-lyase A activity

Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane.


chaperone-mediated autophagy translocation complex disassembly

The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components.


response to trichostatin A

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.


DNA double-strand break processing involved in repair via synthesis-dependent strand annealing

The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing.


high-affinity ferric iron transmembrane transporter activity

Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


low-affinity L-arginine transmembrane transporter activity

Enables the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.


anterior Malpighian tubule development

The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.


L-proline betaine metabolic process

The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants.


Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-.


deoxyadenosine kinase activity

Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H+.


Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.


L-methionine biosynthetic process from L-homoserine via cystathionine

The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine.


phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine

The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine.


peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid

The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid.


pallium cell proliferation in forebrain

The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.


riboflavinase activity

Catalysis of the reaction: H2O + H+ + riboflavin = D-ribitol + lumichrome.


regulation of filamentous growth of a population of unicellular organisms

Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms.


hippurate hydrolase activity

Catalysis of the reaction: N-benzoylglycine + H2O = benzoate + glycine.


nectary development

The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure.


negative regulation of heptasaccharide transport

Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport.


lytic endotransglycosylase activity

Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends.


maleylpyruvate hydrolase activity

Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate.


peptidyl-tryptophan oxidation to tryptophyl quinone

The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine.


intracellular accumulation of glycerol

The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment.


gamma-glutamyl hercynylcysteine sulfoxide synthase activity

Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 = gamma-glutamyl-hercynyl cysteine sulfoxide + H2O.


immune response in brain or nervous system

An immune response taking place in the brain or nervous system.


technetium (VII) reductase activity

Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-.


Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD+ = 3,4-dihydroxybenzoate + CO2 + NADH.


cellular response to acrylamide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.


protoderm histogenesis

The formation of the primary meristem or meristematic tissue that gives rise to the epidermis.


fructoseglycine metabolic process

The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group.


plasmodesma organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.


Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate.


conversion of glutamyl-tRNA to glutaminyl-tRNA

The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA.


D-glucuronate catabolic process

The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.


suppression by symbiont of host defense-related programmed cell death

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


methyl beta-D-glucoside 6-phosphate glucohydrolase activity

Catalysis of the reaction: methyl beta-D-glucoside 6-phosphate + H2O = beta-D-glucose 6-phosphate + methanol.


ammeline aminohydrolase activity

Catalysis of the reaction: ammeline + H2O = ammelide + NH3.


erythrophore differentiation

The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance.


Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin.


pyochelin metabolic process

The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).


alpha-pinene catabolic process

The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.


regulation of substance P secretion

Any process that modulates the frequency, rate or extent of substance P secretion.


ornithine catabolic process

The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.


pheromone catabolic process

The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.


Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine.


regulation of systemic arterial blood pressure by chemoreceptor signaling

The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.


Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.


Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.


positive regulation of hippocampal neuron apoptotic process

Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in hippocampal neurons.


negative regulation of eye photoreceptor cell development

Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.


Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide.


carboxynorspermidine dehydrogenase I activity

Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+.


Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein].


flavonol synthase activity

Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.


myosin II filament assembly

The formation of a bipolar filament composed of myosin II molecules.


regulation of thyroid-stimulating hormone secretion

Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion.


negative regulation of sebum secreting cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation.


Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate.


negative regulation of centriole elongation

Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation.


Catalysis of the reaction: 6-endo-hydroxycineole + NAD+ = 6-oxocineole + H+ + NADH.


cellular response to chemical stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.


posterior lateral line neuromast development

The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.


pinene metabolic process

The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.


nuclear pore localization

Any process in which nuclear pores are transported to, or maintained in, a specific location.


membrane depolarization during ventricular cardiac muscle cell action potential

The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.


Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H+.


regulation of abscisic acid-activated signaling pathway

Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.


Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.


interleukin-25 production

The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)

Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


embryonic development via the syncytial blastoderm

The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.


meiosis I cell cycle phase

A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.


L-idonate 5-dehydrogenase activity (NAD-dependent)

Catalysis of the reaction: L-idonate + NAD = 5-dehydro-D-gluconate + NADH + H+.


Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H+. This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring.


phenylalkylamine binding

Binding to phenylalkylamine or one of its derivatives.


citryl-CoA lyase activity

Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.


(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity

Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate.


catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.


negative regulation of slow-twitch skeletal muscle fiber contraction

Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction.


vanadium ion transmembrane transporter activity

Enables the transfer of vanadium (V) ions from one side of a membrane to the other.


The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


negative regulation of abscisic acid-activated signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.


macromolecule biosynthetic process

The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


negative regulation of lymphoid progenitor cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation.


(+)-taxifolin 5'-hydroxylase activity

Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O.


3-chlorocatechol biosynthetic process

The chemical reactions and pathways resulting in the formation of 3-chlorocatechol.


Catalysis of the reaction: 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O.


protein serine kinase activity (using GTP as donor)

Catalysis of the reactions: GTP + L-seryl-[protein] = GDP + H+ + O-phospho-L-seryl-[protein].


galactose 1-dehydrogenase activity

Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+.


Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2.


1,4-alpha-glucan branching enzyme activity

Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.


positive regulation of mitotic DNA damage checkpoint

Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.


Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H+.


Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.


hip joint articular cartilage development

The process whose specific outcome is the progression of hip joint articular cartilage over time, from its formation to the mature structure.


Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).


negative regulation of glutamate-cysteine ligase activity

Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase.


specification of segmental identity, maxillary segment

The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


hindgut contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.


disassembly by symbiont of host cuticle

The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to dextromethorphan

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.


oxidoreductase activity, acting on hydrogen as donor, with other known acceptors

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound.


Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid.


caudal fin development

The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.


nucleocytoplasmic carrier activity

Binding to and carrying a cargo between the nucleus and the cytoplasm by moving along with the cargo. The cargo can be either a RNA or a protein.


R1/R6 cell differentiation

The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.


L-cysteine transaminase activity

Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.


oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP.


Catalysis of the reaction: an N-terminal L-alpha-aminoacyl-[protein] + L-arginyl-tRNA(Arg) = H+ + N-terminal L-arginyl-L-amino acid-[protein] + tRNA(Arg).


alpha-beta T cell proliferation involved in immune response

The expansion of an alpha-beta T cell population by cell division as part of an immune response.


chondro-4-sulfatase activity

Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H+ + sulfate.


mycothione reductase activity

Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.


NADPH peroxidase activity

Catalysis of the reaction: H2O2 + H+ + NADPH = 2 H2O + NADP+.


O antigen polymerase activity

Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide.


hemocyte proliferation

The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.


detection of electrical stimulus involved in sensory perception

The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception.


Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+.


translation at postsynapse

Translation that occurs at the postsynapse.


Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate.


specification of connecting tubule identity

The process in which the connecting tubule of the kidney nephron acquires its identity.


L-tryptophan decarboxylase activity

Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine.


myoblast fate specification involved in skeletal muscle regeneration

The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.


positive regulation of hemocyte differentiation

Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.


rhombomere 4 structural organization

The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


pseudohyphal septin ring assembly

The aggregation, arrangement and bonding together of septins and associated proteins to form a tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection.


phlobaphene biosynthetic process

The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


negative regulation of Frizzled Nuclear Import pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of a Frizzled Nuclear Import pathway.


phosphatidylserine flippase activity

Catalysis of the movement of phosphatidylserine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.


dorsal closure, leading edge cell fate determination

The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.


negative regulation of cornification

Any process that stops, prevents or reduces the frequency, rate or extent of cornification.


Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate.


positive regulation of mesodermal cell fate determination

Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination.


formaldehyde transketolase activity

Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone.


arthrospore formation

The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.


circadian regulation of systemic arterial blood pressure by hormone

The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.


DNA alpha-glucosyltransferase activity

Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.


vanillin biosynthetic process

The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.


mitochondrial RNA localization

Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.


amygdalin beta-glucosidase activity

Catalysis of the reaction: (R)-amygdalin + H2O = (R)-prunasin + D-glucose.


phosphate butyryltransferase activity

Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.


negative regulation of growth of unicellular organism as a thread of attached cells

Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


response to pheromone regulating pheromone-induced unidirectional conjugation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that regulates the process of pheromone-induced unidirectional conjugation.


phytoene dehydrogenase activity

Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.


peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine

The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.


induction by virus of host cell-cell fusion

The process of syncytia-forming cell-cell fusion, caused by a virus.


growth factor dependent regulation of skeletal muscle satellite cell proliferation

Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.


negative regulation by symbiont of host cholinergic synaptic transmission

Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.


Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP.


15-cis-phytoene synthase activity

Catalysis of the reaction: 2 geranylgeranyl diphosphate -> 15-cis-phytoene + 2 diphosphate.


Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate.


vancomycin biosynthetic process

The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.


negative regulation of leukocyte adhesion to vascular endothelial cell

Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.


aspartate binding

Binding to aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.


chemokine (C-X-C motif) ligand 9 production

The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


response to p-xylene

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus.


regulation of border follicle cell migration

Any process that modulates the frequency, rate or extent of border follicle cell migration.


larval lymph gland hemopoiesis

The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.


response to gibberellin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.


extracellular ATP signaling

The series of molecular signals mediated by the detection of extracellular ATP.


steroid 17-alpha-monooxygenase activity

Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O.


pantetheine kinase activity

Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate.


Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate.


regulation of plant organ formation

Any process that modulates the frequency, rate or extent of plant organ formation.


inositol 3-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H+.


regulation of defense response to insect

Any process that modulates the frequency, rate or extent of defense response to insect.


deaminated glutathione amidase activity

Catalysis of the reaction: N-(4-oxoglutarate)-L-cysteinylglycine + H2O = 2-oxoglutarate + L-cysteinylglycine.


oleate peroxygenase activity

Catalysis of the reaction: oleate + a lipid hydroperoxide <=> 9,10-epoxystearate + a lipid alcohol.


detection of cytokinin stimulus

The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal.


Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.


double-stranded miRNA binding

Binding to double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures.


4 iron, 3 sulfur cluster binding

Binding to a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria.


hydroxyethylthiazole kinase activity

Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H+.


verbascose synthase activity

Catalysis of the reaction: 2 stachyose <=> verbascose + raffinose.


retinal cone cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


septin ring disassembly

The controlled breakdown of a septin ring.


prenol kinase activity

Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity.


(-)-lactol dehydrogenase activity

Catalysis of the reaction: (-)-lactol + NAD <=> H+ + (-)-matairesinol + NADH.


mesonephric interstitial fibroblast differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.


peptide antigen assembly with MHC class Ib protein complex

The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.


cellular response to oxidised low-density lipoprotein particle stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidized lipoprotein particle stimulus.


regulation of pancreatic A cell differentiation

Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.


detoxification of hydrogen peroxide

Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.


regulation of pyloric antrum smooth muscle contraction

Any process that modulates the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


tensidol A metabolic process

The chemical reactions and pathways involving tensidol A.


positive regulation of ascus development

Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.


myosin II filament organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.


wing disc pattern formation

The process giving rise to the pattern of cell differentiation in the wing imaginal disc.


negative regulation by host of symbiont programmed cell death

Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP.


negative regulation of pharynx morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis.


quercetin gentiobioside 1,6-glucosyltransferase activity

Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+.


patchoulene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene.


retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate.


negative regulation of toxin transport

Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport.


gibberellin-15(closed lactone form),2-oxoglutarate:oxygen oxidoreductase (3beta-hydroxylating) activity

Catalysis of the reaction: gibberellin A15 (closed lactone form) + O2 + 2-oxoglutarate = gibberellin A37 (closed lactone form) + succinate + carbon dioxide.


negative regulation of antifungal innate immune response

Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response.


coenzyme gamma-F420-2 biosynthetic process

The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2.


cellular response to platinum ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.


(+)-neomenthol dehydrogenase activity

Catalysis of the reaction: (+)-neomenthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.


Catalysis of the reaction: cyanidin 5-O-beta-D-glucoside + UDP-alpha-D-glucose = cyanin betaine + UDP.


envenomation resulting in modulation of mast cell degranulation in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism.


xylan O-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan.


hippocampal neuron apoptotic process

Any apoptotic process that occurs in a hippocampal neuron.


positive regulation of eosinophil extravasation

Any process that activates or increases the frequency, rate or extent of eosinophil extravasation.


quercetin O-glucoside biosynthetic process

The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.


peptide cross-linking via L-cysteinyl-5-imidazolinone glycine

The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.


cell adhesion involved in single-species biofilm formation in or on host organism

The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species.


regulation of fumigaclavine C biosynthetic process

Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process.


microglial cell migration

The orderly movement of a microglial cell from one site to another.


The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).


homologous chromosome orientation in meiotic metaphase I

The cell cycle process in which the sister centromeres and kinetochores of one chromosome are fused and orientated so the chromosomes attach to microtubules that emanate from the same spindle pole. This process ensures that homologous l chromosomes are segregated at anaphase of meiosis I.


proteasome storage granule disassembly

The disaggregation of a proteasome storage granule into its constituent components.


ureide metabolic process

The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants.


positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.


Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate.


Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP+ = benzyl 2-methyl-3-oxobutanoate + H+ + NADPH.


ATPase-coupled arsenite transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).


lysine biosynthetic process

The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.


Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.


locomotion

Self-propelled movement of a cell or organism from one location to another.


negative regulation of Schwann cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.


peptidyl-serine O-glucuronidation

The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine.


Catalysis of the reaction: 2-butyl-4-hydroxy-5-methyl-3(2H)-furanone + NADP <=> (2E)-2-butylidene-4-hydroxy-5-methyl-3(2H)-furanone + NADPH + H+.


peripheral tolerance induction to nonself antigen

Tolerance induction to nonself antigens in the periphery.


endothelin maturation

The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.


regulation of metanephric podocyte development

Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.


Catalysis of the reaction: 2-oxoglutarate + O2 + 7-[(3S)-(3-amino-3-carboxypropyl)]-wyosine37 in tRNAPhe = succinate + carbon dioxide + 7-(2-hydroxy-3-amino-3-carboxypropyl)-wyosine37 in tRNAPhe.


glycine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine.


Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.


sensory perception of hot stimulus

The series of events required for an organism to receive a hot temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.


cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity

Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+.


Bacillus subtilis ribonuclease activity

Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides.


suppression by virus of host tetherin activity

Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects.


oligosaccharide reducing-end xylanase activity

Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.


endoribonuclease activity involved in viral induction of host mRNA catabolic process

Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA.


phototransduction, UV

The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.


CDP-glucose 4,6-dehydratase activity

Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O.


nucleate erythrocyte differentiation

The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.


regulation of ERBB3 signaling pathway

Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway.


gibberellin A53,2-oxoglutarate:oxygen oxidoreductase activity (GA97-forming)

Catalysis of the reaction: gibberellin A53 + 2-oxoglutarate + O2 = gibberellin A97 + succinate + carbon dioxide.


lipoteichoic acid immune receptor activity

Combining with lipoteichoic acid and transmitting the signal to initiate an innate immune response.


2,4-dichlorophenoxyacetic acid metabolic process

The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.


Catalysis of the reaction: castasterone + UDP-alpha-D-glucose <=> castasterone-23-O-glucoside + UDP + H+.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol.


Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD+ = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


amine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine.


imidazolonepropionase activity

Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H2O = N-formimidoyl-L-glutamate + H+.


regulation of anther dehiscence

Any process involved in the dehiscence of an anther to release the pollen grains contained within it.


protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


sulfatide binding

Binding to sulfatide, also known as 3-O-sulfogalactosylceramide, SM4, or sulfated galactocerebroside. Sulfatide is a class of sulfoglycolipid, which are glycolipids that contain a sulfate group.


beta-nitroacrylate reductase activity

Catalysis of the reaction: 3-nitropropanoate + NADP+ = 3-nitroacrylate + H+ + NADPH.


cell-cell signaling involved in lung development

Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.


iron incorporation into protein via tetrakis-L-cysteinyl iron

The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein).


disruption by virus of host JAK-STAT cascade

A process in which a virus interferes with, inhibits or stops the JAK-STAT signal cascade in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


type B pancreatic cell fate commitment

The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.


organelle localization by membrane tethering

The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other.


Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose. The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.


negative regulation of development, heterochronic

Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.


positive regulation of response to endoplasmic reticulum stress

Any process that activates or increases the frequency, rate or extent of response to endoplasmic reticulum stress.


response to phenylalanine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.


[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity

Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.


response to triterpenoid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triterpenoid stimulus.


negative regulation of chanoclavine-I aldehyde biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.


8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity

Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+.


response to clopidogrel

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.


cytochrome biosynthetic process

The chemical reactions and pathways resulting in the formation of a cytochrome.


Catalysis of the reaction: H+ + UDP-alpha-D-galacturonate = CO2 + UDP-L-arabinose.


vesicle fusion with vacuole

The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.


C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity

Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.


negative regulation of cellular response to iron ion starvation

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation.


swim bladder maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.


methanol oxidation

The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.


toluene dioxygenase activity

Catalysis of the reaction: H+ + NADH + O2 + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD+.


protein-glutamine glutaminase activity

Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.


canonical Wnt signaling pathway involved in mesonephros development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


demethylkotanin catabolic process

The chemical reactions and pathways resulting in the breakdown of demethylkotanin.


RNA biosynthetic process

The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.


negative regulation of toll-like receptor 5 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


regulation of chylomicron remnant clearance

Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.


Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.


serotonin biosynthetic process from tryptophan

The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.


regulation of response to G1 DNA damage checkpoint signaling

Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.


phytochromobilin biosynthetic process

The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.


regulation of penetration hypha formation

Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


multiple spine synapse organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and one or more dendritic spines.


s-triazine compound metabolic process

The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.


anterior head segmentation

Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.


succinate-semialdehyde dehydrogenase (NADP+) activity

Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+.


L-lysine 6-monooxygenase (NADPH) activity

Catalysis of the reaction: L-lysine + NADPH + O2 = N(6)-hydroxy-L-lysine + H2O + NADP+.


placental growth factor receptor activity

Combining with placental growth factor (PlGF) receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.


L-lysine catabolic process to acetyl-CoA via L-pipecolate

The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.


demethoxycurcumin synthase activity from feruloylacetyl-CoA

Catalysis of the reaction: feruloylacetyl-CoA + 4-coumaryl-CoA + H2O = demethoxycurcumin + 2 coenzyme A + carbon dioxide.


monoacylglycerol biosynthetic process

The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.


neural crest-derived cardiac fibroblast cell development

The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.


atrial cardiac muscle cell fate commitment

The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.


arabinogalactan protein metabolic process

The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures.


esculetin biosynthetic process

The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin.


ferulate catabolic process

The chemical reactions and pathways resulting in the breakdown of ferulate.


modulation by virus of host cytokine production

Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism.


Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP.


regulation protein catabolic process at synapse

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse.


positive regulation of starch catabolic process

Any process that activates or increases the frequency, rate or extent of starch catabolic process.


diorcinol metabolic process

The chemical reactions and pathways involving diorcinol.


non-membrane-bounded organelle assembly

The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle.


mesonephric glomerular basement membrane development

The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.


Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.


regulation of hepatic stellate cell migration

Any process that modulates the frequency, rate or extent of hepatic stellate cell migration.


basal dendrite development

The process whose specific outcome is the progression of a basal dendrite over time, from its formation to the mature structure.


negative regulation of motor neuron migration

Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration.


viral release via suppression of host peptidoglycan biosynthetic process

The dissemination of mature viral particles from a host cell, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.


regulation of zinc ion transmembrane import

Any process that modulates the frequency, rate or extent of zinc ion import.


Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA.


quercetin 3-glucoside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP.