regulation of follicle cell microvillus length

A process that modulates the length of a microvillus on a follicle cell.


positive regulation of endosome organization

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that activates or increases the frequency, rate or extent of endosome organization.


negative regulation of vitellogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis.


negative regulation of G-quadruplex DNA unwinding

Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding.


negative regulation of mitotic actomyosin contractile ring assembly

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.


positive regulation of cell-substrate junction organization

Any process that activates or increases the frequency, rate or extent of cell-substrate junction organization.


regulation of fusion of virus membrane with host plasma membrane

Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane.


positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly

Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.


positive regulation of motor neuron axon guidance

Any process that activates or increases the frequency, rate or extent of motor neuron axon guidance.


negative regulation of oocyte karyosome formation

Any process that stops, prevents, or reduces the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


negative regulation of AIM2 inflammasome complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of AIM2 inflammasome complex assembly.


negative regulation of SNARE complex disassembly

Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


negative regulation of mitotic cohesin ssDNA (lagging strand) loading

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin ssDNA (lagging strand) loading.


negative regulation of plasma membrane bounded cell projection assembly

Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly.


regulation of motor neuron axon guidance

Any process that modulates the frequency, rate or extent of motor neuron axon guidance.


regulation of neuron projection arborization

Any process that modulates the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.


positive regulation of DNA duplex unwinding

Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding.


negative regulation of dendrite extension

Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension.


positive regulation of metaphase/anaphase transition of meiosis I

Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.


regulation of synapse pruning

Any process that modulates the frequency, rate or extent of synapse pruning.


positive regulation of exocyst assembly

Any process that increases the rate or extent of exocyst assembly.


regulation of collateral sprouting of injured axon

Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.


negative regulation of capsule organization

Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization.


positive regulation by symbiont of host receptor-mediated endocytosis

Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.


negative regulation of primary cell septum biogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis.


positive regulation of DNA helicase activity

Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity.


negative regulation of low-density lipoprotein receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.


positive regulation of septation initiation signaling

Any process that activates or increases the frequency, rate or extent of septation initiation signaling.


regulation of mitotic spindle formation (spindle phase one)

Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


negative regulation of cristae formation

Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation.


negative regulation of chondrocyte hypertrophy

Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.


regulation of vesicle fusion with Golgi apparatus

Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus.


negative regulation of synaptic assembly at neuromuscular junction

Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic assembly at neuromuscular junction.


negative regulation of gut granule assembly

Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly.


negative regulation of microvillus assembly

Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly.


regulation of cohesin unloading

Any process that modulates the frequency, rate or extent of cohesin unloading.


positive regulation of sensory neuron axon guidance

Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance.


positive regulation of cohesin loading

Any process that activates or increases the frequency, rate or extent of cohesin loading.


negative regulation of DNA recombinase mediator complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly.


positive regulation of Golgi vesicle fusion to target membrane

Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.


regulation of mitotic cohesin loading

Any process that modulates the frequency, rate or extent of mitotic cohesin loading.


negative regulation of postsynaptic density assembly

Any process that decreases the rate, frequency, or extent of postsynaptic density assembly.


positive regulation of endosomal vesicle fusion

Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion.


negative regulation of pseudohyphal growth

Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.


positive regulation of phosphatidylserine exposure on apoptotic cell surface

Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.


negative regulation of axonemal microtubule depolymerization

Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.


positive regulation of SNARE complex disassembly

Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric

Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.


regulation of terminal button organization

Any process that modulates the frequency, rate or extent of terminal button organization.


regulation of Lewy body formation

Any process that modulates the frequency, rate or extent of Lewy body formation.


negative regulation of dorsal/ventral axon guidance

Any process that stops, prevents or reduces the frequency, rate or extent of dorsal/ventral axon guidance.


negative regulation of collagen fibril organization

Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization.


positive regulation of chloroplast fission

Any process that activates or increases the frequency, rate or extent of chloroplast fission.


negative regulation of bleb assembly

Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly.


positive regulation of myosin II filament organization

Any process that activates or increases the frequency, rate or extent of myosin II filament organization.


regulation of anterior/posterior axon guidance

Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance.


modulation by symbiont of host receptor-mediated endocytosis

The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.


negative regulation of division septum assembly

Any process that decreases the frequency, rate or extent of division septum formation. division septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric

Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.


negative regulation of synaptic vesicle uncoating

Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating.


positive regulation of metaphase/anaphase transition of meiosis II

Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II.


positive regulation of mating projection assembly

Any process that activates or increases the frequency, rate or extent of mating projection assembly.


negative regulation of mitotic spindle formation (spindle phase one)

Any process that stops, prevents or reduces the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


regulation of assembly of large subunit precursor of preribosome

Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome.


positive regulation of G-quadruplex DNA unwinding

Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding.


positive regulation of vesicle fusion with Golgi apparatus

Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus.


pointed-end actin filament uncapping

The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.


negative regulation of synapse structural plasticity

Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity.


negative regulation of motile cilium assembly

Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly.


regulation of oocyte karyosome formation

Any process that modulates the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


nucleotide-excision repair, preincision complex stabilization

The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.


regulation of postsynaptic neurotransmitter receptor internalization

Any process that modulates the frequency, rate or extent of endocytosis of neurotransmitter receptor at the postsynapse.


negative regulation of mitotic nuclear envelope disassembly

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.


negative regulation of phagosome maturation

Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation.


regulation of lateral attachment of mitotic spindle microtubules to kinetochore

Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.


positive regulation of synaptonemal complex assembly

Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly.


positive regulation of intermediate filament depolymerization

Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization.


cell growth mode switching, bipolar to monopolar

The process in which a cell switches from bipolar cell growth to monopolar cell growth.


negative regulation of maintenance of mitotic sister chromatid cohesion, arms

Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.


regulation of bacterial-type flagellum assembly

Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly.


termination of monopolar cell growth

Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.


positive regulation of lysosome organization

Any process that activates or increases the frequency, rate or extent of lysosome organization.


positive regulation of centriole elongation

Any process that activates or increases the frequency, rate or extent of centriole elongation.


positive regulation of kinetochore assembly

Any process that activates or increases the frequency, rate or extent of kinetochore assembly.


positive regulation of chromosome condensation

Any process that activates or increases the frequency, rate or extent of chromosome condensation.


positive regulation of cohesin unloading

Any process that activates or increases the frequency, rate or extent of cohesin unloading.


regulation of Atg1/ULK1 kinase complex assembly

Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.


regulation of root hair elongation

Any process that modulates the frequency, rate or extent of root hair elongation.


regulation of macropinocytosis

Any process that modulates the frequency, rate or extent of macropinocytosis.


regulation of primary cell septum biogenesis

Any process that modulates the frequency, rate or extent of primary cell septum biogenesis.


positive regulation of oocyte karyosome formation

Any process that activates or increases the frequency, rate or extent of oocyte karyosome formation, the chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.


regulation of inhibitory synapse assembly

Any process that modulates the frequency, rate or extent of inhibitory synapse assembly.


regulation of DNA duplex unwinding

Any process that modulates the frequency, rate or extent of DNA duplex unwinding.


regulation of G protein-coupled receptor internalization

Any process that modulates the frequency, rate or extent of G protein-coupled receptor internalization.


negative regulation of cohesin unloading

Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading.


regulation of phosphatidylserine exposure on apoptotic cell surface

Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.


negative regulation of fusion of sperm to egg plasma membrane

Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.


positive regulation of mitotic division septum assembly

Any process that activates or increases the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


positive regulation of synapse maturation by synaptic transmission

Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.


negative regulation of membrane invagination

Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination.


regulation of SNARE complex disassembly

Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


negative regulation of lipid droplet fusion

Any process that stops, prevents, or reduces the frequency, rate or extent of lipid droplet fusion.


positive regulation by symbiont of host vacuole organization

The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism.


positive regulation of SNARE complex assembly

Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


regulation of myosin II filament disassembly

Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules.


negative regulation of pseudopodium assembly

Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.


negative regulation of postsynaptic density organization

Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization.


regulation of Wnt-Frizzled-LRP5/6 complex assembly

Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.


negative regulation of unidimensional cell growth

Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.


positive regulation of mitotic actomyosin contractile ring assembly

Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.


regulation of excitatory synapse pruning

Any process that modulates the frequency, rate or extent of excitatory synapse pruning.


negative regulation of non-canonical inflammasome complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical inflammasome complex assembly.


regulation of formation of growth cone in injured axon

Any process that modulates the frequency, rate or extent of formation of growth cone in injured axon.


regulation of DNA helicase activity

Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity.


positive regulation of shelterin complex assembly

Any process that activates or increases the frequency, rate or extent of shelterin complex assembly.


regulation of G-quadruplex DNA unwinding

Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding.


negative regulation of fusion of virus membrane with host plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane.


regulation of mitotic division septum assembly

Any process that modulates the frequency, rate or extent of mitotic division septum formation. Division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


positive regulation of intraciliary anterograde transport

Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport.


mitotic cohesin unloading

Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle.


positive regulation of Lewy body formation

Any process that activates or increases the frequency, rate or extent of Lewy body formation.


regulation of linear element assembly

Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.


negative regulation of monopolar cell growth

Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.


regulation of nodal receptor complex assembly

Any process that modulates the frequency, rate or extent of nodal receptor complex assembly.


negative regulation of endosome organization

Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.


negative regulation of cytoplasmic mRNA processing body assembly

Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.


positive regulation of maintenance of mitotic sister chromatid cohesion, arms

Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.


positive regulation of melanosome organization

Any process that activates or increases the frequency, rate or extent of melanosome organization.


negative regulation of cohesin loading

Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


positive regulation of engulfment of apoptotic cell

Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell.


positive regulation of macropinocytosis

Any process that activates or increases the frequency, rate or extent of macropinocytosis.


positive regulation of metaphase/anaphase transition of meiotic cell cycle

Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.


negative regulation of metaphase/anaphase transition of meiosis II

Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.


modulation by virus of syncytium formation via plasma membrane fusion

The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


positive regulation of bleb assembly

Any process that activates or increases the frequency, rate or extent of bleb assembly.


positive regulation of cellulosome assembly

Any process that activates or increases the frequency, rate or extent of cellulosome assembly.


negative regulation of Atg1/ULK1 kinase complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.


positive regulation of division septum assembly

Any process that increases the frequency, rate or extent of division septum formation. division septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.


negative regulation of podosome assembly

Any process that stops, prevents or reduces the rate or extent of podosome assembly.


positive regulation of heterochromatin organization

Any process that activates or increases the frequency, rate or extent of heterochromatin organization.


regulation of cristae formation

Any process that modulates the frequency, rate or extent of cristae formation.


positive regulation of neuron projection arborization

Any process that activates or increases the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.


positive regulation of bicellular tight junction assembly

Any process that activates or increases the frequency, rate or extent of tight junction assembly.


positive regulation of cellular component organization

Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.


positive regulation of attachment of mitotic spindle microtubules to kinetochore

Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.


regulation of microtubule nucleation by Ran protein signal transduction

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals in which a Ran GTPase relays a signal resulting in the modulation of the rate, frequency or extent of microtubule nucleation.


negative regulation of direction of cell growth

Any process that decreases the direction of cell growth.


regulation of modification of synaptic structure

Any process that modulates the frequency, rate or extent of modification of synaptic structure.


regulation of maintenance of meiotic sister chromatid cohesion, centromeric

Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.


negative regulation of mitotic cohesin dsDNA (leading strand) loading

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin dsDNA (leading strand) loading.


regulation of modification of postsynaptic structure

Any process that modulates the frequency, rate or extent of modification of postsynaptic structure.


positive regulation of anterior/posterior axon guidance

Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance.


regulation of cell septum assembly

Any process that modulates the frequency, rate or extent of cell septum assembly.


positive regulation of mitotic cohesin loading

Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading.


regulation of metaphase/anaphase transition of meiosis I

Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.


regulation of endosomal vesicle fusion

Any process that modulates the frequency, rate or extent of endosomal vesicle fusion.


regulation of bleb assembly

Any process that modulates the frequency, rate or extent of bleb assembly.


regulation of presynapse organization

Any process that modulates the physical form of a presynapse.


negative regulation of receptor-mediated endocytosis involved in cholesterol transport

Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.


regulation of direction of cell growth

Any process that modulates the direction of cell growth.


regulation of initiation of mating projection growth

Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.


positive regulation of AIM2 inflammasome complex assembly

Any process that activates or increases the frequency, rate or extent of AIM2 inflammasome complex assembly.


negative regulation of septation initiation signaling

Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.


positive regulation of mitotic spindle formation (spindle phase one)

Any process that activates or increases the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase (spindle phase one).


regulation of clathrin coat assembly

Any process that modulates the frequency, rate or extent of clathrin coat assembly.


negative regulation of engulfment of apoptotic cell

Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell.


negative regulation of intralumenal vesicle formation

Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation.


cohesin unloading

Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA.


regulation of linear element maturation

Any process that modulates the rate, frequency or extent of linear element maturation.


regulation of COPII vesicle uncoating

Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released.


regulation of sensory neuron axon guidance

Any process that modulates the frequency, rate or extent of sensory neuron axon guidance.


regulation of presynapse assembly

Any process that modulates the frequency, rate or extent of presynapse assembly.


positive regulation of mitotic chromosome condensation

Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.


regulation of synaptic membrane adhesion

Any process that modulates the frequency, rate or extent of adhesion between pre- and post-synaptic membranes.


regulation of motile cilium assembly

Any process that modulates the frequency, rate or extent of motile cilium assembly.


positive regulation of vacuole fusion, non-autophagic

Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.


regulation of shelterin complex assembly

Any process that modulates the frequency, rate or extent of shelterin complex assembly.


negative regulation of cell-substrate junction organization

Any process that stops, prevents or reduces the frequency, rate or extent of cell-substrate junction organization.


positive regulation of secondary cell septum biogenesis

Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis.


negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric

Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.


negative regulation of secretory granule organization

Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization.


negative regulation of neuron projection arborization

Any process that stops, prevents or reduces the frequency, rate or extent of the process in which the anatomical structures of a neuron projection are generated and organized into branches.


positive regulation of pseudohyphal septin ring assembly

Any process that increases the rate, frequency or extent of pseudohyphal septin ring formation.


regulation of heterochromatin organization

Any process that modulates the frequency, rate, extent or location of heterochromatin organization.


negative regulation of extracellular matrix constituent secretion

Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.


negative regulation of inhibitory synapse assembly

Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly.


positive regulation of motile cilium assembly

Any process that activates or increases the frequency, rate or extent of motile cilium assembly.


regulation of follicle cell microvillus organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.


negative regulation of extracellular matrix assembly

Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.


regulation of free ubiquitin chain polymerization

Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization.


regulation of microtubule anchoring at centrosome

Any process that modulates the frequency, rate or extent of microtubule anchoring at centrosome.


negative regulation of spindle assembly

Any process that stops, prevents or reduces the frequency, rate or extent of spindle assembly.


positive regulation of chromatin organization

Any process that activates or increases the frequency, rate or extent of chromatin organization.


regulation of cellulosome assembly

Any process that modulates the frequency, rate or extent of cellulosome assembly.


positive regulation of free ubiquitin chain polymerization

Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization.


negative regulation of plasma membrane repair

Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair.


regulation of mediator complex assembly

Any process that modulates the frequency, rate or extent of mediator complex assembly.


activation of mitotic cell cycle spindle assembly checkpoint

Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint.


negative regulation of mitotic chromosome condensation

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.


negative regulation of motor neuron axon guidance

Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron axon guidance.


regulation of receptor-mediated endocytosis involved in cholesterol transport

Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.


positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric

Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.


negative regulation of DNA recombinase disassembly

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombinase complex disassembly, the disaggregation of a DNA recombinase complex into its constituent components.


regulation of synaptic vesicle membrane organization

Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization.


negative regulation of sensory neuron axon guidance

Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance.


positive regulation of beta-catenin-TCF complex assembly

Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly.


negative regulation of type IV pilus biogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis.


regulation of phragmoplast microtubule organization

Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization.


regulation of membrane invagination

Any process that modulates the frequency, rate or extent of membrane invagination.


negative regulation of Lewy body formation

Any process that stops, prevents or reduces the frequency, rate or extent of Lewy body formation.


negative regulation of bacterial-type flagellum assembly

Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly.


regulation of termination of mating projection growth

Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi.


negative regulation of endosomal vesicle fusion

Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion.


positive regulation of clathrin coat assembly

Any process that activates or increases the frequency, rate or extent of clathrin coat assembly.


negative regulation of Wnt-Frizzled-LRP5/6 complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.


regulation of unidimensional cell growth

Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.


negative regulation of cell growth involved in contact inhibition

The negative regulation of cell growth in response to increased cell density.


positive regulation of formin-nucleated actin cable assembly

Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.


positive regulation of excitatory synapse assembly

Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly.


regulation of protein insertion into mitochondrial outer membrane

Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial outer membrane.


positive regulation of bacterial-type flagellum assembly

Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly.


negative regulation of apoptotic cell clearance

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance.


barbed-end actin filament uncapping

The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.


regulation of cell wall chitin metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.


negative regulation of maintenance of meiotic sister chromatid cohesion

Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


positive regulation of mitotic actomyosin contractile ring disassembly

Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring disassembly.


regulation of myosin II filament assembly

Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules.


regulation of attachment of mitotic spindle microtubules to kinetochore

Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.


regulation of myosin II filament organization

Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.


regulation of gut granule assembly

Any process that modulates the frequency, rate or extent of gut granule assembly.


regulation of synaptonemal complex assembly

Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.


regulation of maintenance of meiotic sister chromatid cohesion

Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


Wnt signaling pathway, regulating spindle positioning

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle.


positive regulation of cell septum assembly

Any process that activates or increases the frequency, rate or extent of cell septum assembly.


negative regulation of Golgi vesicle fusion to target membrane

Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.


regulation of modification of postsynaptic actin cytoskeleton

Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton.


negative regulation of meiosis I

Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.


positive regulation of meiosis I spindle assembly checkpoint

Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint.


regulation of intermediate filament depolymerization

Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament.


negative regulation of myosin II filament assembly

Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly.


modulation by symbiont of host vacuole organization

Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism.


positive regulation of presynaptic active zone assembly

Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.


regulation of postsynaptic density organization

Any process that modulates the frequency, rate or extent of postsynaptic density organization.


negative regulation of metaphase/anaphase transition of meiotic cell cycle

Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.


negative regulation of synaptic vesicle membrane organization

Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization.


positive regulation of cristae formation

Any process that activates or increases the frequency, rate or extent of cristae formation.


regulation of stress granule assembly

Any process that modulates the rate, frequency or extent of stress granule assembly, the aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.


regulation of monopolar cell growth

Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.


negative regulation of shelterin complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of shelterin complex assembly.


regulation of COPII vesicle coating

Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.


negative regulation of melanosome organization

Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.


regulation of formation of translation initiation ternary complex

Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.


positive regulation of spermatid nuclear differentiation

Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.


negative regulation of spermatid nuclear differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.


positive regulation of synaptic vesicle uncoating

Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating.


positive regulation of Atg1/ULK1 kinase complex assembly

Any process that activates or increases the frequency, rate or extent of Atg1/ULK1 kinase complex assembly.


regulation of postsynaptic specialization assembly

Any process that modulates the frequency, rate or extent of postsynaptic specialization assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynaptic specialization.


negative regulation of phosphatidylserine exposure on apoptotic cell surface

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.


negative regulation of supramolecular fiber organization

Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.


regulation of metaphase/anaphase transition of meiotic cell cycle

Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.


regulation of death-inducing signaling complex assembly

Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly.


regulation of proteasome core complex assembly

Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.


regulation of collagen fibril organization

Any process that modulates the frequency, rate or extent of collagen fibril organization.


positive regulation of maintenance of meiotic sister chromatid cohesion

Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.


regulation of rate of cell growth

Any process that modulates the rate of cell growth.


negative regulation of actin filament annealing

Any process that stops, prevents or reduces the frequency, rate or extent of actin filament annealing, i.e. the end-to-end joining of existing actin filaments.


activation of microtubule nucleation

Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.


positive regulation of microvillus assembly

Any process that activates or increases the frequency, rate or extent of microvillus assembly.


regulation of pollen tube growth

Any process that modulates the frequency, rate or extent of pollen tube growth.


negative regulation of macrophage fusion

Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.


regulation of phospholipid scramblase activity

Any process that modulates the frequency, rate or extent of phospholipid scramblase activity.


negative regulation of macropinocytosis

Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis.


positive regulation of protein localization to actin cortical patch

Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch.


positive regulation of BMP secretion

Any process that activates or increases the frequency, rate or extent of BMP secretion.


negative regulation by symbiont of host protein localization to phagocytic vesicle

Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.


negative regulation of Wnt protein secretion

Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


positive regulation of protein localization to meiotic spindle pole body

Any process that increases the frequency, rate or extent of protein localization to a meiotic spindle pole body.


regulation of protein localization to spindle pole body

Any process that modulates the frequency, rate or extent of protein localization to spindle pole body.


positive regulation of endosome to plasma membrane protein transport

Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.


positive regulation of protein localization to basolateral plasma membrane

Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.


negative regulation of lipoprotein transport

Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport.


regulation of t-SNARE clustering

Any process that modulates the frequency, rate or extent of t-SNARE clustering.


negative regulation of protein localization to phagocytic vesicle

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle.


positive regulation of protein localization to centrosome

Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.


regulation of protein localization to cell-cell junction

Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.


positive regulation of protein localization to presynapse

Any process that activates or increases the frequency, rate or extent of protein localization to presynapse.


positive regulation of protein localization to kinetochore

Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore.


regulation of protein localization to cell leading edge

Any process that modulates the frequency, rate or extent of protein localization to cell leading edge.


regulation of asymmetric protein localization involved in cell fate determination

Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.


negative regulation of protein localization to lysosome

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome.


regulation of post-translational protein targeting to membrane, translocation

Any process that modulates the frequency, rate or extent of posttranslational protein translocation through the ER membrane.


negative regulation of protein localization to microtubule

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.


negative regulation of protein localization to cell leading edge

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.


negative regulation of protein localization to actin cortical patch

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch.


regulation of protein localization to chromatin

Any process that modulates the frequency, rate or extent of protein localization to chromatin.


negative regulation of receptor clustering

Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering.


negative regulation of establishment of protein localization to telomere

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere.


positive regulation of secretion of lysosomal enzymes

Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.


regulation of protein localization to cell cortex

Any process that modulates the frequency, rate or extent of protein localization to cell cortex.


regulation of axo-dendritic protein transport

Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.


positive regulation of axo-dendritic protein transport

Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport.


regulation of protein targeting to vacuole involved in autophagy

Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy.


positive regulation of Wnt protein secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.


positive regulation of protein localization to endoplasmic reticulum

Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.


positive regulation of matrix metallopeptidase secretion

Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion.


regulation of protein localization to prospore membrane

Any process that modulates the frequency, rate or extent of protein localization to prospore membrane.


negative regulation of protein localization to basolateral plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane.


negative regulation of renin secretion into blood stream

Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream.


positive regulation of protein localization to membrane

Any process that activates or increases the frequency, rate or extent of protein localization to membrane.


regulation of BMP secretion

Any process that modulates the frequency, rate or extent of BMP secretion.


negative regulation of protein localization to ciliary membrane

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane.


regulation of protein localization to lysosome

Any process that modulates the frequency, rate or extent of protein localization to lysosome.


positive regulation of protein targeting to vacuole involved in autophagy

Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy.


positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway

A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion.


negative regulation of protein localization to spindle pole body

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body.


regulation of protein localization to presynapse

Any process that modulates the frequency, rate or extent of protein localization to presynapse.


negative regulation of protein localization to cell-cell junction

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction.


negative regulation of protein localization to non-growing cell tip

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a non-growing cell tip.


negative regulation of pancreatic amylase secretion

Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion.


regulation of protein localization to phagocytic vesicle

Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle.


regulation of protein localization to centrosome

Any process that modulates the frequency, rate or extent of protein localization to centrosome.


regulation of protein localization to cell tip

Any process that modulates the frequency, rate or extent of protein localization to cell tip.


negative regulation of protein localization to cell cortex

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.


negative regulation of protein localization to nucleolus

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.


regulation of lipoprotein transport

Any process that controls lipoprotein transport.


regulation of protein localization to membrane

Any process that modulates the frequency, rate or extent of protein localization to membrane.


negative regulation of secretion of lysosomal enzymes

Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.


negative regulation of matrix metallopeptidase secretion

Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion.


positive regulation of protein localization to cell leading edge

Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge.


regulation of protein localization to kinetochore

Any process that modulates the frequency, rate or extent of protein localization to kinetochore.


negative regulation of protein localization to membrane

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.


negative regulation of protein localization to cilium

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.


positive regulation of protein localization to endosome

Any process that activates or increases the frequency, rate or extent of protein localization to endosome.


regulation of protein localization to mitotic spindle pole body

Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.


negative regulation of BMP secretion

Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion.


positive regulation of pancreatic amylase secretion

Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion.


regulation of protein localization to endoplasmic reticulum

Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.


positive regulation of protein localization to ciliary membrane

Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.


regulation of protein localization to ciliary membrane

Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane.


negative regulation of protein localization to centrosome

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome.


positive regulation of protein localization to lysosome

Any process that activates or increases the frequency, rate or extent of protein localization to lysosome.


negative regulation of protein localization to presynapse

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse.


negative regulation of skeletal muscle acetylcholine-gated channel clustering

Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.


negative regulation of prolactin secretion

Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.


regulation of protein localization to endosome

Any process that modulates the frequency, rate or extent of protein localization to endosome.


negative regulation of protein localization to cell cortex of cell tip

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to the cell cortex of the cell tip.


positive regulation of protein localization to cell-cell junction

Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction.


positive regulation of protein localization to cell cortex

Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.


regulation of matrix metallopeptidase secretion

Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion.


regulation of protein localization to basolateral plasma membrane

Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane.


regulation of protein localization to non-growing cell tip

Any process that modulates the frequency, rate or extent of protein localization to a non-growing cell tip.


positive regulation of protein localization to prospore membrane

Any process that activates or increases the frequency, rate or extent of protein localization to prospore membrane.


negative regulation of protein localization to kinetochore

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore.


positive regulation of lipoprotein transport

Any process that activates or increases the rate or extent of lipoprotein transport.


positive regulation of protein localization to cell tip

Any process that activates or increases the frequency, rate or extent of protein localization to cell tip.


regulation of pancreatic trypsinogen secretion

Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion.


regulation of protein localization to cilium

Any process that modulates the frequency, rate or extent of protein localization to cilium.


regulation of glutamate receptor clustering

Any process that modulates the frequency, rate or extent of glutamate receptor clustering.


regulation of AMPA glutamate receptor clustering

Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering.


regulation of pancreatic amylase secretion

Any process that modulates the frequency, rate or extent of pancreatic amylase secretion.


regulation of protein localization to adherens junction

Any process that modulates the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


regulation of protein localization to microtubule

Any process that modulates the frequency, rate or extent of protein localization to microtubule.


negative regulation of t-SNARE clustering

Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering.


negative regulation of protein localization to endosome

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.


positive regulation of protein import into chloroplast stroma

Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma.


negative regulation of protein localization to adherens junction

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


regulation of protein localization to actin cortical patch

Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch.


positive regulation of protein localization to cilium

Any process that activates or increases the frequency, rate or extent of protein localization to cilium.


positive regulation of protein localization to spindle pole body

Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body.


negative regulation of protein localization to meiotic spindle pole body

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to a meiotic spindle pole body.


positive regulation of asymmetric protein localization involved in cell fate determination

Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.


regulation of protein localization to meiotic spindle pole body

Any process that modulates the frequency, rate or extent of protein localization to a meiotic spindle pole body.


negative regulation of protein localization to Cajal body

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body.


regulation of protein targeting to vacuolar membrane

Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane.


negative regulation of asymmetric protein localization involved in cell fate determination

Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.


regulation of MAPK export from nucleus

Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm.


regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

Any process that modulates the frequency, rate or extent of neurotransmitter receptor localization to postsynaptic specialization membrane.


positive regulation of protein targeting to vacuolar membrane

Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane.


negative regulation of protein localization to mitotic spindle pole body

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body.


regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane

Any process that modulates the frequency, rate or extent of the directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.


positive regulation of protein export from nucleus during meiotic anaphase II

Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II.


negative regulation of protein localization to chromatin

Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin.


positive regulation of t-SNARE clustering

Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.


regulation of protein localization by the Cvt pathway

Any process that modulates the frequency, rate or extent of protein localization by the Cvt pathway.


regulation of endosome to plasma membrane protein transport

Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.


positive regulation of chromosome passenger complex localization to kinetochore

Any process that activates or increases the frequency, rate or extent of a chromosome passenger complex localization to kinetochore.


regulation of protein localization to cell cortex of cell tip

Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip.


positive regulation of pancreatic trypsinogen secretion

Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion.


positive regulation of protein localization to phagocytic vesicle

Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle.


positive regulation of protein export from nucleus in response to glucose starvation

Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose.


positive regulation of protein localization to chromatin

Any process that activates or increases the frequency, rate or extent of protein localization to chromatin.


regulation of protein import into chloroplast stroma

Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma.


negative regulation of protein localization to cell tip

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip.


negative regulation of pancreatic trypsinogen secretion

Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion.


negative regulation of protein localization to endoplasmic reticulum

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.


myopathy caused by variation in FKRP

biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:ThingWithTaxon

Any myopathy in which the cause of the disease is a variation in the FKRP gene.


qualitative or quantitative defects of alpha-dystroglycan


autosomal recessive limb-girdle muscular dystrophy type 2U

Any autosomal recessive limb-girdle muscular dystrophy in which the cause of the disease is a mutation in the ISPD gene.


qualitative or quantitative defects of protein glycosyltransferase-like


muscular dystrophy-dystroglycanopathy type B5

A congenital muscular dystrophy characterized by autosomal recessive inheritance of muscular dystrophy with variable penetrance of intellectual disability and structural brain abnormalities that has material basis in homozygous or compound heterozygous mutation in the FKRP gene on chromosome 19q13.3.


autosomal recessive limb-girdle muscular dystrophy type 2O

Autosomal recessive limb-girdle muscular dystrophy type 2O (LGMD2O) is a form of limb-girdle muscular dystrophy characterized by an onset in childhood or adolescence of rapidly progressive proximal limb muscle weakness (particularly affecting the neck, hip girdle, and shoulder abductors), hypertrophy in the calves and quadriceps, ankle contractures, and myopia.


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 8

Any muscular dystrophy-dystroglycanopathy, type A in which the cause of the disease is a mutation in the POMGNT2 gene.


qualitative or quantitative defects of protein involved in O-glycosylation of alpha-dystroglycan


primary qualitative or quantitative defects of alpha-dystroglycan


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 7

Any muscular dystrophy-dystroglycanopathy, type A in which the cause of the disease is a mutation in the ISPD gene.


myopathy caused by variation in POMGNT1

Any myopathy in which the cause of the disease is a variation in the POMGNT1 gene.


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A13


myopathy caused by variation in POMT2

Any myopathy in which the cause of the disease is a variation in the POMT2 gene.


limb-girdle muscular dystrophy due to POMK deficiency

Limb-girdle muscular dystrophy due to POMK deficiency is a form of limb-girdle muscular dystrophy presenting in infancy with muscle weakness and delayed motor development (eventually learning to walk at 18 months of age) followed by progressive proximal weakness, pseudohypertrophy of calf muscles, mild facial weakness, and borderline intelligence.


myopathy caused by variation in POMT1

Any myopathy in which the cause of the disease is a variation in the POMT1 gene.


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A5


qualitative or quantitative defects of protein O-mannosyltransferase 1


qualitative or quantitative defects of fukutin


muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B3


qualitative or quantitative defects of FKRP


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 10

Any muscular dystrophy-dystroglycanopathy, type A in which the cause of the disease is a mutation in the RXYLT1 gene.


autosomal recessive limb-girdle muscular dystrophy type 2K

Autosomal recessive limb-girdle muscular dystrophy type 2K (LGMD2K) is a form of limb-girdle muscular dystrophy characterized by the onset of slowly progressive proximal muscle weakness during childhood (with fatigue and difficulty running and climbing stairs) and developmental delay. Mild intellectual deficit and microcephaly, without any obvious structural brain abnormality, are found in all patients. Mild pseudohypertrophy and joint contractures of the ankles have also been reported.


muscle-eye-brain disease

A rare, congenital muscular dystrophy due to dystroglycanopathy characterized by early onset muscular dystrophy, severe muscular hypotonia, severe mental retardation and typical brain and eye malformations, including pachygyria, polymicrogyria, agyria, brainstem and cerebellar structural anomalies, severe myopia, glaucoma, optic nerve and retinal hypoplasia. Patients may present with seizures, macrocephaly or microcephaly, microphthalmia, and congenital contractures. Depending on the severity, limited motor function is acquired. Less severe cases have been reported.


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 12

Any muscular dystrophy-dystroglycanopathy, type A in which the cause of the disease is a mutation in the POMK gene.


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A9


autosomal recessive limb-girdle muscular dystrophy type 2I

Autosomal recessive limb-girdle muscular dystrophy type 2I (LGMD2I) is a subtype of autosomal recessive limb-girdle muscular dystrophy that presents a highly variable age of onset and phenotypic spectrum typically characterized by slowly progressive proximal weakness of the pelvic and shoulder girdle musculature (predominantly affecting the lower limbs), frequently associated with waddling gait, scapular winging, calf and tongue hypertrophy, exercise-induced myalgia, and myoglobinuria and/or elevated creatine kinase serum levels. Abdominal muscle weakness, cardiomyopathy, respiratory muscle involvement and various brain abnormalities have also been reported.


autosomal recessive limb-girdle muscular dystrophy type 2N

Autosomal recessive limb-girdle muscular dystrophy type 2N (LGMD2N) is a form of limb-girdle muscular dystrophy characterized by proximal weakness (manifesting as slowness in running) presenting in infancy, along with calf hypertrophy, mild lordosis, scapular winging and normal intelligence or mild intellectual disability.


muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B2

An autosomal recessive inherited congenital muscular dystrophy caused by mutations in the POMT2 gene. It is characterized by mental retardation and mild structural brain abnormalities resulting from defective glycosylation of alpha-dystroglycan.


qualitative or quantitative defects of protein O-mannose beta1, 2N-acetylglucosaminyltransferase


qualitative or quantitative defects of protein O-mannosyltransferase 2


muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a, 11

Any muscular dystrophy-dystroglycanopathy, type A in which the cause of the disease is a mutation in the B3GALNT2 gene.


muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B1


left suprarenal vein

biolink:GrossAnatomicalStructure biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A vein that drains blood from the left adrenal gland into the left renal artery.


galanin-activated signaling pathway

The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor.


Broad Ligament Papillary Cystadenoma

A cystadenoma that arises from the broad ligament. It is characterized by the presence of small papillary projections in the inner surface of the cysts. It may be sporadic or associated with von Hippel-Lindau disease.


bile acid taurine conjugate

A bile acid conjugate resulting from the formal condensation of a bile acid with the amino group of taurine.


5beta-cholanic acids

Members of the class of cholanic acids based on a 5beta-cholane skeleton.


hydroxy-5beta-cholanic acid

Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position.


bile acid conjugate

Any bile acid conjugated to a functional group that gives additional hydrophilicity or charge to the molecule. Molecules used for conjugation are: glycine, taurine (and other amino acids); sulfuric acid (for which the term ''sulfate'' may be used); glucuronic acid (for which the term ''glucuronate'' may be used); glucose and other uncharged sugars; and coenzyme A.


dihydroxy-5beta-cholanic acid

A hydroxy-5beta-cholanic acid carrying two hydroxy groups at unspecified positions.


bile acid

Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration.


bile acids

Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration.


dihydroxycholanic acid

Any member of the class of cholanic acids carrying two hydroxy substituents at unspecified positions.


acyl-CoA N-acyltransferase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.


Cervical Warty Carcinoma

A human papillomavirus-related cervical squamous cell carcinoma characterized by the presence of a warty surface and koilocytotic atypia.


congenital vascular bone syndrome

An alteration in limb growth caused by congenital vascular malformations in childhood.


angioosteohypotrophic syndrome

Angioosteohypotrophic syndrome is a rare, congenital, vascular anomaly syndrome characterized by venous or, on occasion, arterial malformations which lead to soft tissue hypertrophy and bone hypoplasia. Affected limb is generally shortened, highly deformed, painful and edematous and associates bone and muscle hypotrophy. Single parts, or multiple small parts, of limbs are typically affected but more extensive involvement, including complete extremity, shoulder girdle and axilla, has been reported.


pseudohypoaldosteronism type 2D

Any pseudohypoaldosteronism type 2 in which the cause of the disease is a mutation in the KLHL3 gene.


temporomandibular joint disorder

Any condition affecting the anatomic and functional characteristics of the temporomandibular joint.


Craniomandibular Disorders

A disorder that affects the muscles of head and neck and temporomandibular joint.


osteofibrous dysplasia

A benign, usually self-limited fibro-osseous lesion of the bone that affects infants and children. It usually arises from the cortical bone of the anterior mid-shaft of the tibia. Patients usually present with swelling or painless bowing of the tibia. Progression to adamantinoma has been reported in some cases.


syringal lignin catabolic process

The chemical reactions and pathways resulting in the breakdown of syringal lignin.


negative regulation of toll-like receptor 9 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.


epaxial region somite 24

The epaxial region of somite 24 derived body wall muscle. The epaxial region is dorsal to the horizontal myoseptum. Kimmel et al, 1995.


Stage IIIC Ovarian Cancer

Stage IIIC includes: (T3c, N0, M0); (Any T, N1, M0). T3c: Peritoneal metastasis beyond pelvis more than 2cm in greatest dimension and/or regional lymph node metastasis. N0: No regional lymph node metastasis.  N1: Regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


Stage IIIB Ovarian Germ Cell Tumor AJCC v6 and v7

Stage IIIB includes: T3b, N0, M0. T3b: Macroscopic peritoneal metastasis beyond pelvis 2 cm or less in greatest dimension. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)


Stage IIB Ovarian Cancer AJCC v8

Stage IIB includes: T2b, N0, M0. T2b: Ovarian cancer with tumor extension to and/or implants on other pelvic tissues. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 8th Ed.)


Stage IIIA Ovarian Cancer AJCC v6 and v7

Stage IIIA includes: T3a, N0, M0.  T3a: Microscopic peritoneal metastasis beyond pelvis (no macroscopic tumor). N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


Ovarian Sex Cord-Stromal Tumor, Not Otherwise Specified

A sex cord-stromal tumor that arises from the ovary and lacks the morphologic features that belong to the categories of granulosa-stromal tumors, Sertoli-stromal tumors, or steroid cell tumors.


Recurrent Malignant Ovarian Brenner Tumor

The reemergence of malignant ovarian Brenner tumor after a period of remission.


Stage IC Ovarian Germ Cell Tumor AJCC v6 and v7

Stage IC includes: (T1c, N0, M0).  T1c: Tumor limited to one or both ovaries with any of the following: capsule ruptured, tumor on ovarian surface, malignant cells in ascites or peritoneal washings.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th Eds.)


FIGO Stage IIIA2 Ovarian Cancer

Ovarian cancer with microscopic, extrapelvic (above the brim) peritoneal involvement +/- positive retroperitoneal lymph nodes. (FIGO, 2014)


ovarian endometrioid stromal and related neoplasms

A category of rare neoplasms that arise from the ovary. It includes low grade endometrioid stromal sarcoma and undifferentiated sarcoma.


Ovarian Neuroendocrine Carcinoma

A small cell carcinoma, pulmonary-type or large cell neuroendocrine carcinoma arising from the ovary.


Borderline Ovarian Mucinous Tumor/Atypical Proliferative Ovarian Mucinous Tumor with Microinvasion

A low grade ovarian epithelial neoplasm characterized by the presence of neoplastic mucinous epithelial cells, atypia, and microinvasion of the ovarian stroma.


Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7

Stage IV includes: Any T, Any N, M1. M1: Distant metastasis (excludes peritoneal metastasis). (AJCC 6th and 7th eds.)


Borderline Ovarian Mixed Epithelial Tumor/Atypical Proliferative Ovarian Mixed Epithelial Tumor

A low grade, non-invasive mixed epithelial proliferative neoplasm that arises from the ovary. In most cases is composed of serous and endocervical-type mucinous cells.


Stage IV Ovarian Cancer AJCC v6 and v7

Stage IV includes: Any T, Any N, M1.  M1: Distant metastasis (excludes peritoneal metastasis). (AJCC 6th and 7th eds.)


Metastatic Ovarian Clear Cell Adenocarcinoma

Ovarian clear cell adenocarcinoma that has spread from its original site of growth to another anatomic site.


Stage IIB Ovarian Germ Cell Tumor AJCC v6 and v7

Stage IIB includes: T2b N0, M0. T2b: Extension and/or implants on other pelvic tissues. No malignant cells in ascites or peritoneal washings. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)


FIGO Stage IVA Ovarian Cancer

Ovarian cancer with pleural effusion with positive cytology. (FIGO, 2014)


Borderline Ovarian Mucinous Tumor

A low grade mucinous epithelial neoplasm arising from the ovary.  It is characterized by an atypical proliferation of mucinous-type epithelial cells without evidence of stromal invasion.  The mucinous epithelial cells may be of intestinal or endocervical type.


Recurrent Ovarian Transitional Cell Carcinoma

The reemergence of ovarian transitional cell carcinoma after a period of remission.


Stage IIIC Ovarian Cancer AJCC v8

Stage IIIC includes: T3c, N0/N1, M0. T3c: Ovarian cancer with macroscopic peritoneal metastasis beyond the pelvis more than 2 cm in greatest dimension with or without metastasis to the retroperitoneal lymph nodes (includes extension of tumor to capsule of liver and spleen without parenchymal involvement of either organ). N0: No regional lymph node metastasis. N1: Positive retroperitoneal lymph nodes only (histologically confirmed). M0: No distant metastasis. (AJCC 8th Ed.)


Ovarian Mixed Cell Adenocarcinoma

An adenocarcinoma that arises from the ovary and is characterized by the presence of two or more adenocarcinoma components, most often endometrioid and clear cell.


Locally Advanced Ovarian Carcinoma

Ovarian carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes.


Recurrent Ovarian Undifferentiated Carcinoma

The reemergence of ovarian undifferentiated carcinoma after a period of remission.


Ovarian Soft Tissue Neoplasm

A benign, intermediate, or malignant mesenchymal neoplasm of the ovary. Representative examples include leiomyoma, myxoma, and sarcoma.


ovarian stromal hyperthecosis

A non-neoplastic disorder that usually affects postmenopausal women. It is characterized by the leuteinization of ovarian stromal cells. The ovaries are bilaterally involved and enlarged. When it affects women in reproductive age, it causes virilization, high blood pressure, and increased insulin levels.


Metastatic Ovarian Carcinosarcoma

Ovarian carcinosarcoma that has spread from its original site of growth to another anatomic site.


Stage I Ovarian Germ Cell Tumor AJCC v6 and v7

Stage I includes: (T1, N0, M0). T1: Tumor limited to ovaries (one or both).  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th Eds.)


malignant sex cord stromal tumor of ovary

Malignant sex cord stromal tumor (SCST) of ovary is a rare ovarian cancer arising from granulosa, theca, sertoli and leydig cells or stromal fibroblasts, occurring at any age and presenting with abdominal or pelvic mass, and characterized (with the exception of fibroma) by the production of sex steroids resulting in manifestations of hormone excess, with a relatively favorable prognosis.


Stage IIIB Ovarian Cancer AJCC v8

Stage IIIB includes: T3b, N0/N1, M0. T3b: Ovarian cancer with macroscopic peritoneal metastasis beyond pelvis 2 cm or less in greatest dimension with or without metastasis to the retroperitoneal lymph nodes. N0: No regional lymph node metastasis. N1: Positive retroperitoneal lymph nodes only (histologically confirmed). M0: No distant metastasis. (AJCC 8th Ed.)


Stage II Borderline Ovarian Surface Epithelial-Stromal Tumor

Stage II includes: T2, N0, M0.  T2: Tumor involves one or both ovaries with pelvic extension and/or implants.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


Ovarian Mucinous Carcinoid Tumor

A rare carcinoid tumor that arises from the ovary and is characterized by the presence of glands that are lined by cells that contain intracytoplasmic mucin or resemble goblet cells.  Pools of mucin, containing glands, may also be present.  It may have an aggressive clinical course and it can metastasize to other anatomic sites.


ovarian Sertoli-Leydig cell tumor

A benign or malignant sex cord-stromal tumor arising from the ovary. It is characterized by the presence of neoplastic Leydig cells. Signs and symptoms include hirsutism, menorrhagia and metrorrhagia. It may be associated with trisomy 8.


Well Differentiated Ovarian Steroid Cell Tumor

An ovarian steroid cell tumor not otherwise specified, and characterized by the absence of nuclear atypia, mitotic figures, necrosis, and hemorrhage.


Refractory Ovarian Clear Cell Adenocarcinoma

Ovarian clear cell adenocarcinoma that is resistant to treatment.


Ovarian Wolffian Tumor

An epithelial neoplasm of Wolffian (mesonephric) origin arising from the ovarian hilum. Most tumors behave in a benign fashion.


Ovarian Stromal-Leydig Cell Tumor

A rare, benign and well circumscribed stromal tumor of the ovary.  It is characterized by the presence of a fibrotic stroma with clusters of Leydig cells.  The Leydig cells contain crystals of Reinke.  Patients may present with virilization.


Stage IIA Ovarian Cancer AJCC V6 and v7

Stage IIA includes: T2a, N0, M0.  T2a: Extension and/or implants on uterus and/or tube(s). No malignant cells in ascites or peritoneal washings.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


non-gestational ovarian choriocarcinoma

A malignant germ cell tumor that arises from the ovary and is composed of cytotrophoblasts, syncytiotrophoblasts, and extravillous trophoblasts. The prognosis is less favorable than gestational choriocarcinoma.


Stage IB Ovarian Germ Cell Tumor AJCC v6 and v7

Stage IB includes: (T1b, N0, M0). T1b: Tumor limited to both ovaries; capsules intact, no tumor on ovarian surface.  No malignant cells in ascites or peritoneal washings.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th Eds.)


Borderline Ovarian Clear Cell Tumor/Atypical Proliferative Ovarian Clear Cell Tumor with Intraepithelial Carcinoma

A non-invasive clear cell adenofibromatous neoplasm that arises from the ovary. It is characterized by the presence of atypical neoplastic clear or hobnail epithelial cells and intraepithelial carcinoma.


FIGO Stage IIIA1(i) Ovarian Cancer

Ovarian cancer with positive retroperitoneal lymph nodes only. Metastasis equal or less than 10 mm. (FIGO, 2014)


malignant non-dysgerminomatous germ cell tumor of ovary

A malignant germ cell tumor other than dysgerminoma that arises from the ovary.


Malignant Ovarian Luteinized Thecoma

A thecoma of the ovary that contains lutein cells and may metastasize to other anatomic sites. It is usually characterized by nuclear atypia and mitotic activity.


ovarian angiosarcoma

A malignant vascular neoplasm arising from the ovary.


Stage II Ovarian Polyembryoma AJCC v6 and v7

Stage II includes: T2, N0, M0. T2: Tumor involves one or both ovaries with pelvic extension and/or implants. N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)


Stage I Borderline Ovarian Surface Epithelial-Stromal Tumor

Stage I includes: T1, N0, M0. T1: Tumor limited to ovaries (one or both).  N0: No regional lymph node metastasis.  M0: No distant metastasis.  (AJCC 6th and 7th eds.)


Stage IIIA Ovarian Germ Cell Tumor AJCC v6 and v7

Stage IIIA includes: T3a, N0, M0. T3a: Microscopic peritoneal metastasis beyond pelvis (no macroscopic tumor). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)


Recurrent Ovarian Carcinosarcoma

The reemergence of ovarian carcinosarcoma after a period of remission.


Ovarian germ cell choriocarcinoma stage II


Recurrent BRCA- Associated Ovarian Carcinoma

The reemergence of BRCA-associated ovarian carcinoma after a period of remission.


ovarian endometriosis

A non-neoplastic disorder characterized by the growth of endometrial tissue in the ovaries. It results in the development of blood filled ovarian cysts (chocolate cysts), and creation of scars and adhesions.


Borderline Ovarian Serous Tumor/Atypical Proliferative Ovarian Serous Tumor

A non-invasive serous neoplasm that arises from the ovary and shows greater cellular proliferation and cytologic atypia as compared to benign ovarian serous tumors, but less as compared to low-grade ovarian serous carcinoma.


ovarian gynandroblastoma

A rare neoplasm arising from the ovary. Although it may occur at any age, it is more often seen in young females. Morphologically, it is characterized by a mixture of two cellular populations: well differentiated Sertoli cells and granulosa cells, with the latter constituting at least ten percent of the neoplasm. The vast majority of cases are stage I lesions at presentation and produce either estrogenic or androgenic manifestations. Although it may present as a massive ovarian tumor, it usually follows a benign clinical course. Very rare case reports of testicular lesions morphologically resembling gynandroblastomas are in fact variants of juvenile granulose cell tumor, or Sertoli cell tumor, or a combination of both.


Stage IIIB Ovarian Cancer AJCC v6 and v7

Stage IIIB includes: T3b, N0, M0.  T3b: Macroscopic peritoneal metastasis beyond pelvis 2 cm or less in greatest dimension. N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


Refractory Extrarenal Rhabdoid Tumor of the Ovary

An extrarenal rhabdoid tumor of the ovary that is resistant to treatment.


Refractory Ovarian Squamous Cell Carcinoma

Ovarian squamous cell carcinoma that is resistant to treatment.


Benign epithelial tumor of ovary

A non-metastasizing tumor that originates from the surface epithelium of the ovary.  It is composed of epithelial cells and stroma.  Representative examples include serous cystadenoma, mucinous cystadenoma, clear cell adenofibroma, and benign Brenner tumor.


ovarian adenosarcoma

A biphasic neoplasm that arises from the ovary and is characterized by the presence of mullerian-type epithelial tissue in a mesenchymal sarcomatous stroma. The presence of a high grade sarcomatous component is associated with recurrences and metastases.


Stage IV Ovarian Polyembryoma AJCC v6 and v7

Stage IV includes: Any T, Any N, M1. M1: Distant metastasis (excludes peritoneal metastasis). (AJCC 6th and 7th eds.)


Ovarian germ cell choriocarcinoma stage I

Stage I includes: T1, N0, M0. T1: Tumor limited to ovaries (one or both). N0: No regional lymph node metastasis. M0: No distant metastasis. (AJCC 6th and 7th eds.)


Ovarian Smooth Muscle Tumor of Uncertain Malignant Potential

A smooth muscle neoplasm that arises from the ovary and cannot be reliably diagnosed as benign or malignant, because of the presence of ambiguous morphologic findings.


Poorly Differentiated Ovarian Sertoli-Leydig Cell Tumor

A Sertoli-Leydig tumor of the ovary characterized by the presence of a sarcomatoid stroma which contains primitive gonadal stromal cells. It may behave in a malignant fashion and metastasize to other anatomic sites.


Malignant Ovarian Thecoma

A thecoma of the ovary which may metastasize to another anatomic site. It is usually characterized by nuclear atypia and mitotic activity. Malignant thecomas are rare.


Ovarian Mucinous Cystic Tumor Associated with Pseudomyxoma Peritonei

The presence of abundant mucoid or gelatinous, cellular or acellular material in the pelvis and abdominal cavity (pseudomyxoma peritonei) that is associated with the presence of an ovarian mucinous cystic tumor.  In the vast majority of cases, the presence of pseudomyxoma peritonei is the result of metastasis from a primary appendiceal or gastrointestinal tumor site, and the ovarian mucinous tumor is metastatic rather than primary.


Ovarian Cancer by AJCC v8 Stage

A term that refers to the staging of ovarian cancer according to the American Joint Committee on Cancer, 8th edition. This staging system applies to ovarian carcinomas. Nonepithelial primary ovarian cancers may be staged using this classification but should be reported separately. (from AJCC 8th Ed.)


Ovarian Signet Ring Stromal Tumor

A rare, benign sex cord-stromal tumor that arises from the ovary. It is characterized by the presence of round cells with a single cytoplasmic vacuole and an eccentric nucleus resembling signet ring cells. Mucin stains are negative.


Stage I Ovarian Dysgerminoma AJCC v6 and v7

Stage I includes: (T1, N0, M0). T1: Tumor limited to ovaries (one or both).  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th Eds.)


Recurrent Ovarian Adenocarcinoma

The reemergence of ovarian adenocarcinoma after a period of remission.


Ovarian Seromucinous Cystadenoma

A non-metastasizing cystic mixed epithelial neoplasm that arises from the ovary. It is characterized by the presence of more than one epithelial cell type, most often serous and endocervical-type mucinous.