low-density lipoprotein particle disassembly involved in cholesterol transport

The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport.


cyclopentanol biosynthetic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways resulting in the formation of cyclopentanol.


ceramide floppase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the movement of ceramide from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


cellular response to ciliary neurotrophic factor

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.


Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine.


glucuronoside biosynthetic process

The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


negative regulation of intracellular cholesterol transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.


focal adhesion disassembly

The disaggregation of a focal adhesion into its constituent components. A focal adhesion is a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also functions as a locus of signal transduction activity.


histone H2AXY142 kinase activity

Catalysis of the reaction: histone H2AX-tyrosine (position 142) + ATP = (histone H2AX-phosphotyrosine (position 142) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 142 of histone variant H2AX.


acetoacetyl-CoA reductase activity

Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.


Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.


detoxification of arsenic-containing substance

Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.


flower structural organization

The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.


Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate.


apoptotic process involved in atrial ventricular junction remodeling

Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.


response to low fluence blue light stimulus by blue low-fluence system

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes.


positive regulation of neutrophil mediated killing of bacterium

Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.


positive regulation of erythrophore differentiation

Any process that activates or increases the frequency, rate or extent of erythrophore differentiation.


response to deep water

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle.


taxifolin 8-monooxygenase activity

Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O.


chlorophyll(ide) b reductase activity

Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.


detection of disaccharide stimulus

The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.


3-methylquinoline catabolic process

The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.


steroid receptor RNA activator RNA binding

Binding to a steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.


ent-kaurene oxidase activity

Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol.


Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine.


negative regulation of exit from meiosis

Any process that stops, prevents or reduces the frequency, rate or extent of exit from meiosis.


carbamoyl-serine ammonia-lyase activity

Catalysis of the reaction: O-carbamoyl-L-serine + H2O + H+ = CO2 + 2 NH4 + pyruvate.


negative regulation of sodium-dependent phosphate transport

Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport.


Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose.


glucosinolate catabolic process

The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


fructosamine metabolic process

The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


imaginal disc-derived wing margin morphogenesis

The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.


beta-alanine biosynthetic process via 1,3 diaminopropane

The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.


N-terminal peptidyl-aspartic acid acetylation

The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.


pharyngeal muscle development

The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.


purine imidazole-ring cyclase activity

Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O.


O-malonyltransferase activity

Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule.


acetate ester metabolic process involved in fermentation

Any acetate ester metabolic process that is involved in fermentation.


cerebroside transfer activity

Directly binding to a cerebroside and delivering it either to an acceptor molecule or to a specific location.


O-octanoyltransferase activity

Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule.


arabinan biosynthetic process

The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.


creatinine deaminase activity

Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3.


negative regulation of potassium ion import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import across the plasma membrane.


magnesium protoporphyrin IX methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H+ + magnesium protoporphyrin IX 13-monomethyl ester.


imaginal disc-derived female genitalia development

The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.


mitotic spindle microtubule depolymerization

The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.


ribitol catabolic process

The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.


carotene beta-ring hydroxylase activity

Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene.


lactate fermentation to propionate and acetate

The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP).


regulation of hydrolase activity

Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.


propionate kinase activity

Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate.


positive regulation of meiotic sister chromatid arm separation

Any process that increases the rate or exent of meiotic sister chromatid arm separation, the cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.


colon epithelial cell chemotaxis

The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


condensed mesenchymal cell proliferation

The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.


mannosylglycerate metabolic process

The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.


tellurite methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride).


modulation by symbiont of host cholinergic synaptic transmission

Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.


Catalysis of the reaction: 5'-adenylyl sulfate + NH4 = adenosine 5'-phosphoramidate + 2 H+ + sulfate.


phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H+ + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.


acetate kinase activity

Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.


autoinducer-2 kinase activity

Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.


ATPase-coupled inorganic anion transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + inorganic anion(out) = ADP + phosphate + inorganic anion(in).


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in).


convergent extension involved in imaginal disc-derived wing morphogenesis

The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis.


mitotic metaphase

The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.


enkephalin processing

The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.


thebaine 6-O-demethylase activity

Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide.


positive regulation of galactomannan catabolic process

Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process.


amyloid precursor protein biosynthetic process

The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of amyloid-beta, a glycoprotein associated with Alzheimer's disease.


rhombomere 7 structural organization

The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate.


right lung development

The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.


Group III intron splicing

The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.


3-formylsalicylate oxidase activity

Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide.


ferrochelatase activity

Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX.


Catalysis of the removal of a methyl group from N-nitrosodimethylamine.


cell proliferation in bone marrow

The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow.


lycopene catabolic process

The chemical reactions and pathways resulting in the breakdown of lycopene.


Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).


proestrus

The estrous cycle phase in which there is heightened follicular activity.


regulation of localization

Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.


positive regulation of astrocyte activation

Any process that increases the frequency, rate or extent of astrocyte activation.


hamamelose kinase activity

Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H+.


The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.


negative regulation of ERBB3 signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.


regulation of thioredoxin peroxidase activity

Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity.


(-)-menthol monooxygenase activity

Catalysis of the reaction: (-)-menthol + H+ + NADPH + O2 = 1,4-menthane-3,8-diol + H2O + NADP+.


short-chain fatty acid-CoA ligase activity

Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.


effector-mediated modulation of host defenses by symbiont

A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


stearoyl-[acp] desaturase activity

Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin.


negative regulation of hypoxia-inducible factor-1alpha signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.


ganglioside GM2 binding

Binding to ganglioside GM2.


regulation of positive chemotaxis to cAMP by DIF-2

Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine.


shikimate 3-dehydrogenase (NAD+) activity

Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.


regulation of sevenless signaling pathway

Any process that modulates the frequency, rate or extent of the sevenless signaling pathway.


Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H+.


alanine dehydrogenase activity

Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+.


negative regulation of cardiac vascular smooth muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.


embryonic liver development

The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.


voltage-gated calcium channel activity involved in bundle of His cell action potential

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


mandelate metabolic process

The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.


cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid

The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.


metanephric glomerular epithelial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.


protein cis-autophosphorylation

The phosphorylation by a protein of one or more of its own amino acid residues.


specification of sepal identity

The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


regulation of blood-brain barrier permeability

Any process that modulates blood-brain barrier permeability, the quality of the blood-brain barrier that allows for a controlled passage of substances (e.g. macromolecules, small molecules, ions) into and out of the brain.


nitroglycerin reductase activity

Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative.


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate.


modulation by symbiont of host erythrocyte aggregation

Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.


citrate secondary active transmembrane transporter activity

Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


3-hydroxyanthranilate oxidase activity

Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2.


nicotinamidase activity

Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.


trichloroethylene catabolic process

The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.


fluorescent chlorophyll catabolite monooxygenase (deformylase) activity

Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite.


nitric oxide transmembrane transporter activity

Enables the transfer of nitric oxide, nitrogen monoxide, from one side of a membrane to the other.


ergothioneine transmembrane transporter activity

Enables the transfer of ergothioneine from one side of a membrane to the other.


negative regulation of intracellular lipid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.


negative regulation of R8 cell spacing in compound eye

Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.


Catalysis of the reduction of a peptide-linked oxazoline to oxazole.


Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O2 = CO2 + H+ + mugineate + succinate.


tectospinal tract morphogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.


proacrosomal vesicle fusion

Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.


Catalysis of the reaction: dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H+ + NADPH.


saccharopine dehydrogenase activity

Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor.


regulation of myofibril size

Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.


actin filament debranching

An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.


W-molybdopterin cofactor metabolic process

The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.


envenomation resulting in positive regulation of mast cell degranulation in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism.


Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate.


formin-nucleated actin cable organization

A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.


rolling circle double-stranded viral DNA replication

A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.


response to thyroxine

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.


germacradienol synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.


genital disc morphogenesis

The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.


[isocitrate dehydrogenase (NADP+)] kinase activity

Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate.


peptidyl-lysine succinylation

The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine.


5' overhang single-stranded DNA endodeoxyribonuclease activity

Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks.


glycerate dehydrogenase activity

Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.


vanillin dehydrogenase activity

Catalysis of the reaction: H2O + NAD+ + vanillin = 2 H+ + NADH + vanillate.


post-embryonic anterior midgut (ectodermal) morphogenesis

The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.


peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine

The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.


ABC-type capsular-polysaccharide transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).


G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential

G protein-coupled neurotransmitter receptor activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential.


renal vesicle progenitor cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.


negative regulation of adaptive immune memory response

Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.


ligand-gated monoatomic cation channel activity

Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


negative regulation of cytokinesis, site selection

Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.


serine-type aminopeptidase activity

Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).


heat dissipation

Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.


positive regulation of cardiac muscle fiber development

Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.


acyl glucuronidation

The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).


post-embryonic pelvic fin morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.


salivary gland boundary specification

Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.


pons formation

The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


positive regulation of toll-like receptor 11 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


estrogen 16-alpha-hydroxylase activity

Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.


5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity

Catalysis of the reaction: 5-HETE + NADP+ = 5-oxo-ETE + NADPH + H+.


muconate cycloisomerase activity

Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.


secalciferol 1-monooxygenase activity

Catalysis of the reaction:2 H+ + O2 + 2 reduced [adrenodoxin] + secalciferol = calcitetrol + H2O + 2 oxidized [adrenodoxin].


polymannuronate hydrolase activity

Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate.


N-carbamoylsarcosine amidase activity

Catalysis of the reaction: N-carbamoylsarcosine + H2O + 2 H+ = CO2 + NH4 + sarcosine.


positive regulation of neutrophil mediated killing of symbiont cell

Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.


alpha-keto amide reductase activity

Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.


positive regulation of estradiol secretion

Any process that activates or increases the frequency, rate or extent of estradiol secretion.


positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis

Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.


ABC-type D-xylose transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in).


histone H3-K4 demethylation, trimethyl-H3-K4-specific

The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.


syncytium formation by mitosis without cytokinesis

The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.


plasmalogen synthase activity

Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine.


nucleoside transmembrane transporter activity, against a concentration gradient

Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.


protein localization to basal ectoplasmic specialization

A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.


fibroblast growth factor receptor apoptotic signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR).


hepatocyte dedifferentiation

The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.


regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity

Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.


regulation of primitive erythrocyte differentiation

Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.


beta-L-arabinosidase activity

Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.


germarium-derived egg chamber formation

Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.


defecation rhythm

The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.


modulation by symbiont of ethylene levels in host

The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of peptidoglycan recognition protein signaling pathway

Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


beak formation

The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.


3,5-xylenol methylhydroxylase activity

Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol.


all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity

Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.


larval locomotory behavior

Locomotory behavior in a larval (immature) organism.


[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity

Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate.


bile-acid 7alpha-dehydratase activity

Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H2O.


positive regulation of establishment or maintenance of cell polarity regulating cell shape

Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.


N-1-naphthylphthalamic acid binding

Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor.


tyramine-beta hydroxylase activity

Catalysis of the hydroxylation of tyramine to form octopamine.


positive regulation of mitotic centrosome separation

Any process that activates or increases the frequency, rate or extent of centrosome separation.


protein localization involved in acrosome reaction

The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.


translation factor activity, non-nucleic acid binding

A translation regulator activity that does not involve binding to nucleic acids.


thermospermine synthase activity

Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.


protein localization to chloroplast starch grain

A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.


seed development

The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.


negative regulation of cerebral blood circulation

Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.


box C/D RNA processing

Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA.


RNA localization to nucleus

A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.


envenomation resulting in negative regulation of blood pressure in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism.


negative regulation of compound eye retinal cell programmed cell death

Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.


cellular response to bacteriocin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


epinephrine catabolic process

The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


carotid body glomus cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.


fucosterol-epoxide lyase activity

Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.


Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H+ + urate.


response to mannitol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.


cholesterol monooxygenase (side-chain-cleaving) activity

Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.


guanosine metabolic process

The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.


protein N-linked N-acetylglucosaminylation via asparagine

A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.


detection of mechanical stimulus involved in sensory perception of gravity

The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.


averantin metabolic process

The chemical reactions and pathways involving averantin.


regulation of leucophore differentiation

Any process that modulates the frequency, rate or extent of leucophore differentiation.


glyoxal catabolic process

The chemical reactions and pathways resulting in the breakdown of glyoxal.


detection of glucocorticoid hormone stimulus

The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


central B cell anergy

Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.


establishment of mitochondrion localization by microtubule attachment

The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.


3-ketovalidoxylamine C-N-lyase activity

Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H+.


negative regulation of ventricular cardiac muscle cell action potential

Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential.


sucrose synthase activity

Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.


specification of carpel identity

The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


Catalysis of the reaction: S-adenosyl-L-methionine + H+ = S-adenosylmethioninamine + CO2.


positive regulation of aecium development

Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.


positive regulation of animal organ morphogenesis

Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.


plant-type cell wall cellulose catabolic process

The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.


pregnan-21-ol dehydrogenase (NAD+) activity

Catalysis of the reaction: NAD+ + pregnan-21-ol = H+ + NADH + pregnan-21-al.


zerumbone synthase activity

Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+.


xanthine oxidase activity

Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide.


negative regulation of nematode male tail tip morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.


phenylcoumaran benzylic ether reductase activity

Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.


protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in).


mating type determination

Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms.


basophil activation involved in immune response

A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.


angioblast cell migration involved in selective angioblast sprouting

The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.


semaphorin-plexin signaling pathway involved in outflow tract morphogenesis

The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.


germ-line stem-cell niche homeostasis

A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.


arginine catabolic process to glutamate

The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.


negative regulation of voltage-gated sodium channel activity in another organism

Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.


detection of gravity

The series of events in which a gravitational stimulus is received and converted into a molecular signal.


negative regulation of D-aspartate import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.


protein flavinylation

The addition of a flavin group to a protein amino acid.


pyridine-3,4-diol dioxygenase activity

Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate.


induction by symbiont of defense-related host reactive oxygen species production

The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


queuosine nucleosidase activity

Catalysis of the reaction: a N-D-queuosine + H2O = queuine + D-ribose.


emericellamide biosynthetic process

The chemical reactions and pathways resulting in the formation of emericellamide.


negative regulation of mesodermal cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.


carotenoid dioxygenase activity

Catalysis of the oxidative cleavage of carotenoids.


Catalysis of the reaction: anhydrotetracycline + H+ + NADPH + O2 = 12-dehydrotetracycline + H2O + NADP+.


positive regulation of presynaptic cytosolic calcium concentration

Any process that increases the concentration of calcium ions in the presynaptic cytosol.


Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+.


oleate 12-hydroxylase activity

Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O.


auxin influx transmembrane transporter activity

Enables the transfer of auxin, from one side of a membrane to the other, into a cell.


positive regulation of chemotaxis to arachidonic acid

Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid.


proteasome storage granule assembly

The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.


rhombomere 3 structural organization

The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


molecular transducer activity

A compound molecular function in which an effector function is controlled by one or more regulatory components.


symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway

A process in which a virus interferes with, inhibits or disrupts a tumor necrosis factor-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


TMP biosynthetic process

The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.


anaerobic lactate catabolic process

The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.


N-sulfoglucosamine-3-sulfatase activity

Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.


learned vocalization behavior

A vocalization behavior that is the result of learning.


adenosyl-fluoride synthase activity

Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.


aminoimidazolase activity

Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH3.


positive regulation of galactotriose transport

Any process that activates or increases the frequency, rate or extent of galactotriose transport.


NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity

Catalysis of the transfer of ADP-ribose groups to the glutamate-2 residue of the N-terminal tail of histone H2B (or an equivalent residue).


voltage-gated sodium channel activity involved in bundle of His cell action potential

Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


positive regulation of arbuscule formation for nutrient acquisition from host

Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


ammonia monooxygenase activity

Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.


Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2.


gramicidin S biosynthetic process

The chemical reactions and pathways resulting in the formation of gramicidin S.


Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP.


G protein-coupled serotonin receptor signaling pathway

The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands.


(+)-sabinol dehydrogenase activity

Catalysis of the reaction: (+)-cis-sabinol + NAD+ = (1S,5S)-sabinone + H+ + NADH.


positive regulation of TRAIL-activated apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.


extracellular matrix organization involved in endocardium development

A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


nitrogenous compound fermentation

The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.


protein localization to microvillus membrane

A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.


protein-lipid complex disassembly

The disaggregation of a protein-lipid complex into its constituent components.


sucrose phosphorylase activity

Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.


regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.


chitin-based cuticle sclerotization

The process of hardening of a chitin-based cuticle.


viral genome maturation

The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.


glycoside biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.


negative regulation of gluconate transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


regulation of planar cell polarity pathway involved in pericardium morphogenesis

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.


bicyclogermacrene metabolic process

The chemical reactions and pathways involving bicyclogermacrene.


arachidonate 8(R)-lipoxygenase activity

Catalysis of the reaction: arachidonate + O2 = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.


skeletal muscle hypertrophy

The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.


disruption of host cell-cell junction

The process by which a symbiont effects a change in the structure or function of an intercellular junction of the host. Intercellular junction include tight junctions and adherens junctions.


cell surface adhesin-mediated gliding motility

Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.


Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.


(1->3),(1->4)-beta-glucan binding

Binding to (1->3),(1->4)-beta-glucan.


positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.


21U-RNA metabolic process

The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


Catalysis of the reaction: N-methyl-2-oxoglutaramate + H2O = 2-oxoglutarate + methylammonium.


NAD-dependent protein depalmitoylase activity

Catalysis of the reaction: N6-octadecanoyl-L-lysyl-[protein] + NAD+ + H2O = octadecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in).


Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.


quiescent center organization

The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure.


centromere-nuclear envelope anchor activity

The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.


alpha-humulene 10-hydroxylase activity

Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O.


glycerol dehydrogenase [NAD+] activity

Catalysis of the reaction: glycerol + NAD+ = glycerone + H+ + NADH.


positive regulation of filamentous growth of a population of unicellular organisms in response to starvation

Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.


slow muscle cell migration

The orderly movement of a slow muscle cell from one site to another.


oleate hydratase activity

Catalysis of the reaction: (R)-10-hydroxystearate = H2O + oleate.


peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid

The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.


enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity

Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+.


aryl-aldehyde dehydrogenase (NAD) activity

Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+.


negative regulation of retrograde axon cargo transport

Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.


Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A.


snRNA methyltransferase activity

Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.


stigma development

The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.


neuron migration involved in retrograde extension

The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension.


positive regulation of small intestine smooth muscle contraction

Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction.


UFM1 ligase activity

Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S = X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.


positive regulation of myofibroblast contraction

Any process that activates or increases the frequency, rate or extent of myofibroblast contraction.


negative regulation of artery smooth muscle contraction

Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction.


nerve maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.


positive regulation of macromolecule metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


regulation of growth plate cartilage chondrocyte differentiation

Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.


negative regulation of tongue muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.


apolysis

The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.


orlandin metabolic process

The chemical reactions and pathways involving orlandin.


positive regulation of synaptic vesicle lumen acidification

Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification.


aerobic benzoate metabolic process

The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.


gibberellin A12,oxoglutarate:oxygen oxidoreductase activity

Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide.


vestibular receptor cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.


response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.


xylene metabolic process

The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.


glutamate synthase (ferredoxin) activity

Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.


2,4,6-trinitrotoluene metabolic process

The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.


phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine

The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


light-dependent bacteriochlorophyll biosynthetic process

The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.


Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate.


U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity

Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.


protein-phosphocysteine-trehalose phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).


apoptotic process involved in tube lumen cavitation

Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.


glycerol-3-phosphate dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+.


regulation of secondary shoot formation

Any process that modulates the frequency, rate or extent of secondary shoot formation.


microcin transmembrane transporter activity

Enables the transfer of a microcin from one side of a membrane to the other.


vesicle fusion with Golgi cis cisterna membrane

The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.


anthocyanin accumulation in tissues in response to UV light

The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.


cellodextrin phosphorylase activity

Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.


chemotaxis to cAMP

The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.


pyrroloquinoline quinone biosynthetic process

The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.


Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.


Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP+ = 5alpha-pregnane-3,20-dione + H+ + NADPH.


tryptamine 4-monooxygenase activity

Catalysis of the reaction: tryptamine + reduced acceptor + O2 <=> 4-hydroxytryptamine + acceptor + H2O.


1-indanone dioxygenase activity

Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone.


regulation of cellular defense response

Any process that modulates the frequency, rate or extent of cellular defense response.


regulation of iron ion transmembrane transporter activity

Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity.


vacuolar sequestering

The process of transporting a substance into, and confining within, a vacuole.


radial glial cell division in pallium

The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.


Catalysis of the reaction: H2S (hydrogen sulfide) + a quinone = S0 (sulfane sulfur) + a hydroquinone.


Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA.


negative regulation of leukocyte adhesion to arterial endothelial cell

Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.


Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.


neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).


response to reversine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.


G-protein gated monoatomic cation channel activity

A cation channel activity that is gated by binding of a G-protein beta-gamma dimer.


2-nitrophenol 2-monooxygenase activity

Catalysis of the reaction: 2-nitrophenol + 2 H+ + 2 NADPH + O2 = catechol + H2O + 2 NADP+ + nitrite.


high-affinity potassium ion transmembrane transporter activity

Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


antigen processing and presentation, endogenous lipid antigen via MHC class Ib

The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.


negative regulation of mesodermal cell fate determination

Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.


Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.


positive regulation of oomycete sporangium development

Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.


regulation of long-day photoperiodism, flowering

Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.


induction of host induced systemic resistance

Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.


1,6-anhydro-N-acetyl-beta-muramic acid metabolic process

The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.


retrotrapezoid nucleus neuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.


hexadecanol dehydrogenase activity

Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH.


4-hydroxytryptamine 4-phosphate methyltransferase activity

Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin.


neurofibrillary tangle assembly

The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle.


DNA nucleotidylexotransferase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).


S-succinyltransferase activity

Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.


Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone.


carbon dioxide transmembrane transporter activity

Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.


dibenzofuran catabolic process

The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.


membrane depolarization during atrial cardiac muscle cell action potential

The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.


dIDP phosphatase activity

Catalysis of the reaction: dIDP + H2O = dIMP + H+ + phosphate.


negative regulation of optic nerve formation

Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.


alpha-L-rhamnosidase activity

Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.


dihydrouracil oxidase activity

Catalysis of the reaction: 5,6-dihydrouracil + O2 = H2O2 + uracil.


Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.


spinal sensory neuron axon guidance

The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.


vertebrate eye-specific patterning

Early postnatal vertebrate developmental process, during which axons of retinal ganglion cells (RGCs), transmitting overlapping inputs from both eyes, segregate into distinct eye-specific non-overlapping regions in the dorsal lateral geniculate nucleus (dLGN) of the thalamus.


pigment accumulation in tissues

The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.


mucilage pectin metabolic process

The chemical reactions and pathways involving the pectin component of mucilage.


sitosterol hydroxylase activity

Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP.


auxin mediated signaling pathway involved in phyllotactic patterning

The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.


positive regulation of biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.


glycerate 2-kinase activity

Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP.


gibberellin 12-aldehyde oxidase activity

Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).


positive regulation of lateral motor column neuron migration

Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration.


Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine.


regulation of action potential firing rate

Any process that regulates the frequency of action potentials in a spike train.


appressorium formation

The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface.


red light photoreceptor activity

The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.


response to papulacandin B

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.


negative regulation of galactoglucomannan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process.


sulfur oxidation, ferric ion-dependent

A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+).


regulation of stomach fundus smooth muscle contraction

Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.


embryo sac morphogenesis

The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.


6G-fructosyltransferase activity

Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).


1-pyrroline dehydrogenase activity

Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.


Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.


Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate.


Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.


Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.


dibenzothiophene monooxygenase activity

Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.


chylomicron binding

Binding to a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.


U2-type prespliceosome assembly

The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome.


microglia development

The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


dibenzothiophene catabolic process

The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.


anaerobic ethylbenzene metabolic process

The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen.


convergent extension involved in somitogenesis

The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.


L-seryl-tRNA(Sec) kinase activity

Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).


Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.


organic acid metabolic process

The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.


regulation of RNA helicase activity

Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.


positive regulation of cell proliferation in midbrain

Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain.


IAA-Leu conjugate hydrolase activity

Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.


Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.


autophagosome-endosome fusion

The process in which an autophagosome fuses with an endosome to create an intermediate autophagic organelle called amphisome.


magnetosome assembly

The aggregation, arrangement and bonding together of a set of components to form a magnetosome. Magnetosomes are specialized organelles for magnetic navigation that comprise membrane-enveloped, nano-sized crystals of a magnetic iron mineral; they are formed by a diverse group of magnetotactic bacteria (MTB).


G/T mismatch-specific thymine-DNA glycosylase activity

Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free thymine and leaving an apyrimidinic (AP) site.


brainstem precerebellar neuron precursor migration

The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.


carpel development

The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.


methylthiotransferase activity

Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.


Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O.


primary adaptive immune response

An adaptive immune response against an antigen not previously encountered by immune system.


2,5-dichlorohydroquinone reductive dehalogenase activity

Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).


pole plasm RNA localization

Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


subthalamic nucleus development

The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.


lipoteichoic acid D-alanylation

The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA).


sensory organ precursor cell division

The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron).


Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.


RITS complex assembly

The aggregation, arrangement and bonding together of a set of components to form a RITS complex.


chloroplast avoidance movement

The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.


locus ceruleus maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.


negative regulation of eating behavior

Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.


hair follicle cell proliferation

The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.


minus-end directed microtubule sliding

The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.


dipeptide transmembrane transporter activity

Enables the transfer of a dipeptide from one side of a membrane to the other. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.


regulation of chromosome separation

Any process that modulates the frequency, rate or extent of chromosome separation.


ascospore wall chitin metabolic process

The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


histone lactyltransferase activity

Catalysis of the reaction: (L-lysyl-[histone] + lactoyl-CoA = CoA + H+ + N(6)-lactoyl-L-lysyl-[histone].


capsanthin synthase activity

Catalysis of the reaction: antheraxanthin = capsanthin.


oxidoreductase activity, acting on reduced flavodoxin as donor

Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].


inositol tetrakisphosphate 6-kinase activity

Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.


anaerobic glycerol catabolic process

The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.


negative regulation of AMPA receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity.


response to capsazepine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.


plastid localization

Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.


ATP diphosphatase activity

Catalysis of the reaction: ATP + H2O = AMP + H+ + diphosphate.


disruption of cell in another organism

The disruption of a cell of another organism, leading to damage or temporary subversion of that cell.


spinal cord anterior/posterior patterning

The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.


accessory nerve maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


negative regulation of galactomannan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process.


lignin metabolic process

The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.


The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs.


beta-glucoside kinase activity

Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.


neutral L-amino acid:sodium:chloride symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral L-amino acid(out) + Na+(out) + Cl-(out) = neutral L-amino acid(in) + Na+(in)+ Cl-(in).


salicylic acid glucosyltransferase (glucoside-forming) activity

Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.


2-hydroxybenzoyl-CoA metabolic process

The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA.


pyrimidine nucleoside transmembrane transporter activity

Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.


SA node cell to atrial cardiac muscle cell communication by electrical coupling

The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.


penetration hypha formation

The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.


urothelial cell proliferation

The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.


aconitate decarboxylase activity

Catalysis of the reaction: cis-aconitate + H+ = CO2 + itaconate.


chloroplast proton-transporting ATP synthase complex assembly

The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.


lens epithelial cell proliferation

The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.


Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.


precorrin-6Y C5,15-methyltransferase (decarboxylating) activity

Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.


phosphatidate kinase activity

Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate.


formation of a compartment boundary

Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.


regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed

A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.


pelvic fin morphogenesis

The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


negative regulation of metula development

Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


neuromast hair cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.


4,6-pyruvylated galactose residue metabolic process

The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.


T-helper 2 cell chemotaxis

The directed movement of a T-helper 2 cell in response to an external stimulus.


citronellyl-CoA dehydrogenase activity

Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+.


regulation of epithelium regeneration

Any process that modulates the frequency, rate or extent of epithelium regeneration.


regulation of otic vesicle morphogenesis

Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.


ribonucleoside binding

Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.


pectin metabolic process

The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge.


diaminopimelate epimerase activity

Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.


peptidyl-cystine sulfhydration

The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide.


Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.


positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization

Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization.