BAD-BCL-xl complex

A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.


NOXA-BCL-xl complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.


dorsal longitudinal anastomotic vessel

biolink:GrossAnatomicalStructure biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Trunk vessel that connects to the primitive hindbrain channel and the basilar artery at the caudal end of the medulla oblongata. Isogai et al. 2001.


lateral dorsal aorta

Connect the outflow of the aortic arches to the dorsal aorta. The place where the lateral dorsal aorta fuse is is called the radiax of the aorta. Isogai et al. 2001.


NSL complex

A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.


skin of external ear

A zone of skin that is part of a external ear [Automatically generated definition].


phosphatidylinositol phosphate phosphatase complex

A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.


dorsal venous arch

The dorsal venous arch of the foot is a superficial vein that connects the small saphenous vein and the great saphenous vein. Anatomically, it is defined by where the dorsal veins of the first and fifth digit, respectively, meet the great saphenous vein and small saphenous vein.


primordial midbrain channel

The vessel between the anterior cerebral vein and the mid cerebral vein. Isogai et al. 2001.


A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.


tricuspid valve anulus

The fibrous ring of the tricuspid valve that attaches the cusps of tricuspid valve to the heart, and which consists of portions of the fibrous scallops of the anterior cusp (infundibular cusp), the posterior cusp (marginal cusp), and the septal cusp (medial cusp).


subscapular vein

A vein formed by the confluence of the thoracodorsal and circumflex scapular veins and accompanying the subscapular artery to drain into the axillary vein.


alpha1-beta1 integrin-tissue transglutaminase complex

A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.


caudal division of the internal carotid artery


ventral abdominal vein

A vein formed by the combination of veins in the pelvic region which collects blood from the liver, stomach, intestines, and gall bladder.


pancreaticoduodenal vein

A vein running parallel to the superior and inferior pancreatico-duodenal arteries that drains blood from the pancreas and duodenum into the superior mesenteric or portal veins.


nitrogenase complex

An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.


anterolateral ligament of knee

A ligament on the lateral aspect of the human knee, anterior to the fibular collateral ligament.


vein of vestibular aqueduct

A vein that leaves the vestibule through an individual bone canal running parallel to the vestibular aqueduct up to the dura of the posterior side of the petrosa in the area of the endolymphatic sac. It then opens in the inferior petrosal sinus or the jugular bulb. The vein receives other branches from the bone, dura and sac.


colonic epithelium

An epithelium that is part of a colon [Automatically generated definition].


vein of clitoris

A vein that is part of a clitoris [Automatically generated definition].


SCF-YLR352W ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.


metanephric nephron epithelium

The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros[GO].


glutamate synthase complex (NADH)

A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.


colon endothelium

Vascular endothelium found in colon blood vessels.


collagen type XIII trimer

A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane.


MPT synthase complex

A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.


Kv4.1-DPP6 channel complex

A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.


superficial cerebral vein

The superficial cerebral veins are a group of veins in the head. This group includes the superior cerebral veins.


metencephalic artery

These arteies branch dorsally from both sides of the posterior communicating artery looping up to join with the opposite MtA as well as with both middle cerebral veins at the dorsal midline of the head. Isogai et al. 2001.


pedal digit 2 epithelium

An epithelium that is part of a pedal digit 2.


ileocolic lymph node

One of the lymph nodes that form a chain around the ileocolic artery.


thymus subcapsular epithelium

The epithelial cells lining the capsule and trabeculae of the thymus.


central artery

Arteries that irrigate the forebrain and midbrain Isogai et al. 2001.


epithelium of upper jaw

An epithelium that is part of a upper jaw [Automatically generated definition].


high-affinity iron exporter complex

A protein complex which transports ferrous iron (Fe(III) or Fe3+) ions from the vacuole, the main storage component of intracellular free iron, into the cytoplasm in a low iron environment.


left umbilical vein

An umbilical vein that is in the left side of a multicellular organism.


methyl coenzyme M reductase complex

A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis.


Grb2-SHP-2 complex

A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.


ovarian follicle stage II

Stage II follicles (140-340 microns) are cortical alveolus stage. Selman et al, 1993.


A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).


pelvis blood vessel

A blood vessel that is part of a pelvis [Automatically generated definition].


extraembryonic endoderm

An extraembryonic epithelium that is formed by the delaminated cells of the primitive endoderm (hypoblast) that goes on to form the yolk sac. In mammals, as in avians, these cells do not produce any part of the newborn organism (i.e. they are extraembryonic).


somite 29

Undifferentiated mesodermal component of early tail segment 29 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


somite 23

Undifferentiated mesodermal component of early tail segment 23 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


mesenteric fat pad

Encapsulated adipose tissue associated with the mesentery.


U4atac/U6atac snRNP

A ribonucleoprotein complex that contains the extensively base paired small nuclear RNAs U4atac and U6atac, a heptameric ring of Sm proteins associated with U4atac, the Lsm2-8 heptameric ring complex associated with U6atac, as well as several proteins that are unique to the U4atac snRNP or U6atac snRNPs, some of which remain associated with the U4atac/U6atac snRNA both while the U4atac snRNP is free or assembled into a series of spliceosomal complexes.


A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.


somite 19

Undifferentiated mesodermal component of early trunk or tail segment 19 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


mitochondrial DNA-directed RNA polymerase complex

A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.


histamine-gated chloride channel complex

A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts.


parotid gland interlobular duct

Any of the excretory ducts of the parotid gland which are found in the connective tissue septa i.e. between lobules.


A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.


cytosolic proteasome core complex, alpha-subunit complex

The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.


H-NS-Cnu complex

A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes.


RAD52-ERCC4-ERCC1 complex

A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.


ADA complex

A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and H2B. In budding yeast shares the histone acetylation (HAT) module of ADA2-GCN5-NGG1-SGF29 with the related SAGA complex.


tertiary ovarian follicle

A follicle that has reached the most mature stage of folliculogenesis, characterized by the presence of the antrum.


myosin XVIII complex

A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.


external naris epithelium

An epithelium that is part of an external naris [Automatically generated definition].


hepatic sinusoid

Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers.


epithelium of ductus reuniens

An epithelium that is part of a ductus reuniens [Automatically generated definition].


mitochondrial prohibitin complex

A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.


maxillary vein

A vein that consists of a short trunk which accompanies the first part of the internal maxillary artery. It is formed by a confluence of the veins of the pterygoid plexus, and passes backward between the sphenomandibular ligament and the neck of the mandible, and unites with the superficial temporal vein to form the retromandibular vein. [WP,unvetted].


glomerular endothelium

The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.


costo-cervical trunk

The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted].


exocrine pancreas

The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO].


cloacal epithelium

An epithelium that is part of a cloaca.


respiratory system blood vessel endothelium

A blood vessel endothelium that is part of a respiratory system [Automatically generated definition].


glomerular endothelium fenestra

A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes.


Pi Mi complex

A transcription factor complex composed of a homeodomain protein and the M-specific peptide Mi that acts at the regulatory region of genes required for the activation of meiosis.


cardiac gastric gland

A gastric gland in the cardiac region of the stomach; cardiac glands are fewer in number than in the fundus and body, and secrete mucin which coats the stomach and protects it[MP].


wall of crypt of Lieberkuhn of large intestine

A wall of crypt of Lieberkuhn that is part of a large intestine.


subtelomeric heterochromatin

Heterochromatin that is located adjacent to the telomere, and characterized by methylated H3 histone at lysine 9 (H3K9me2/H3K9me3).


future central tendon

A tendon that has the potential to develop into a central tendon.


neurotransmitter receptor complex

Any protein complex that is capable of functioning as a neurotransmitter receptor.


right anterior flagellum

A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell.


IgA immunoglobulin complex, circulating

A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


multi-pass translocon complex

A protein complex that mediates the insertion of multi-pass transmembrane proteins into endoplasmic reticulum (ER) membrane. Substrates enter via the lateral gate of the Sec61 translocon. The complex comprises the GEL subcomplex (composed of RAB5IF/OPTI and TMCO1), the BOS subcomplex (composed of NCLN/Nicalin, NOMO and TMEM147) and the PAT subcomplex (composed of WDR83OS/Asterix and CCDC47).


sucrase-isomaltase complex

A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.


cytosolic proteasome regulatory particle

A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.


basal vein

The basal vein is formed at the anterior perforated substance by the union of (a) a small anterior cerebral vein which accompanies the anterior cerebral artery and supplies the medial surface of the frontal lobe by the fronto-basal vein. (b) the deep middle cerebral vein (deep Sylvian vein), which receives tributaries from the insula and neighboring gyri, and runs in the lower part of the lateral cerebral fissure, and (c) the inferior striate veins, which leave the corpus striatum through the anterior perforated substance. The basal vein passes backward around the cerebral peduncle, and ends in the internal cerebral vein; it receives tributaries from the interpeduncular fossa, the inferior horn of the lateral ventricle, the hippocampal gyrus, and the mid-brain.


anterior mediastinal lymph node

A lymph node located in the superior mediastinum that collects lymph from the thymus, the pericardium, and the right side of the heart.


alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex

A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.


superficial temporal artery

A major artery of the head that arises from the external carotid artery when it bifurcates into the superficial temporal artery and maxillary artery. Its pulse is palpable superior to the zygomatic arch, anterior and superior to the tragus. [WP,unvetted].


mitochondrial respiratory chain complex I, peripheral segment

The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.


deferent duct vein

A vein that is part of a vas deferens [Automatically generated definition].


mitochondrial glutamate synthase complex (NADH)

A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.


renal afferent arteriole

The blood vessels that branch from the kidney interlobular artery, convey blood to the glomerular capillaries, and play an important role in the regulation of blood pressure as a part of the tubuloglomerular feedback mechanism.


caspase complex

A protein complex that contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes.


stratum corneum of epidermis

The outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells.


keratinized stratified squamous epithelium

Keratinized stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesize and accumulate keratin.


gastrocnemius vein

A vein that drains the gastrocnemius.


diencephalon pia mater

A pia mater that is part of a diencephalon [Automatically generated definition].


eukaryotic translation initiation factor 3 complex, eIF3e

An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.


ATP-dependent citrate lyase complex

A protein complex that catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA.


Tapasin-ERp57 complex

Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.


cytosolic aryl hydrocarbon receptor complex

An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.


epithelium of biliary system

The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts.


mesentery of midgut

A mesentery that is part of a midgut [Automatically generated definition].


optic vein

Vein that connects to the hyaloid vein that drains the eye. External to eye. Isogai et al. 2001.


superior superficial cervical thymic artery


subcutaneous adipose tissue

A portion of adipose tissue that is part of the hypodermis, beneath the dermis.


somite 6

Undifferentiated mesodermal component of early trunk segment 6 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


obturator vein

The obturator vein begins in the upper portion of the adductor region of the thigh and enters the pelvis through the upper part of the obturator foramen, in the obturator canal. It runs backward and upward on the lateral wall of the pelvis below the obturator artery, and then passes between the ureter and the hypogastric artery, to end in the hypogastric vein. It has an anterior and posterior branch (similar to obturator artery). [WP,unvetted].


vesical artery

An artery that supplies blood to the urinary bladder.


conjunctival vein

A vein that is part of a conjunctiva.


greater sac mesothelium

A mesothelium that is part of a greater sac.


spinal dura mater

A dura mater that is part of a spinal cord [Automatically generated definition].


A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.


pharyngeal arch artery 2

The vessels formed within the second pair of branchial arches in embryogenesis.


kidney capillary

A capillary that is part of a kidney [Automatically generated definition].


transitional epithelium of major calyx

An urothelium of ureter that is part of a mucosa of major calyx.


RNA polymerase V transcription repressor complex

A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter.


alphaV-beta3 integrin-laminin alpha-4 complex

A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4.


cartilage of bronchus

The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP].


chloroplast small ribosomal subunit

The small subunit of a ribosome contained within a chloroplast.


alpha4-beta1 integrin-JAM2 complex

A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.


9+2 motile cilium

A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).


epithelium of small intestine

An epithelium that is part of a small intestine [Automatically generated definition].


interscapular fat pad

Encapsulated adipose tissue located between the scapulae.


hyoidean artery

An artery that passes along the ventral portions of the hyoid arch; supplies oxygenated blood to the pseudobranch.


subcostal vein

A vein that runs along the bottom of the lowest rib. Each subcostal vein gives off a posterior (dorsal) branch which has a similar distribution to the posterior ramus of an intercostal artery. [WP,modified].


gastrointestinal system serosa

A serous membrane that is part of a digestive system [Automatically generated definition].


protein C inhibitor-acrosin complex

A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.


extracellular ferritin complex

A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains.


C/EBP complex

A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities.


meninx of hindbrain

A meninx that is part of a hindbrain [Automatically generated definition].


meniscus

Crescent-shaped fibrocartilaginous structure present in the knee, acromioclavicular, sternoclavicular, and temporomandibular joints[2] that, in contrast to articular disks, only partly divides a joint cavity.[3] A small meniscus also occurs in the radio-carpal joint.


ESCRT IV complex

An ESCRT complex that has AAA-ATPase activity and is involved in ESCRT-mediated intralumenal vesicle formation and the final stages of cytokinesis. The complex catalyzes disassembly of the ESCRT III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.


acid phosphatase complex

A protein complex which is capable of acid phosphatase activity.


TRAPPII protein complex

A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the phagophore assembly site. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.


superior epigastric artery

An artery that arises from the internal thoracic arteryand anastomoses with the inferior epigastric artery at the umbilicus and supplies the anterior part of the abdominal wall and some of the diaphragm.


right subcostal vein

A vein that extends along the bottom of the twelfth rib on the right side of the body.


lateral vein

Either of the veins which collect blood from the trunk and skin and drain into the subclavian vein.


metapterygoid-autopalatine ligament

Ligament that connects the metapterygoid to the autopalatine.


supraorbital gland

A lateral nasal gland that removes sodium chloride from the bloodstream.


cerebellar vein

A vein that drains the cerebellum.


tRNA (m7G46) methyltransferase complex

A protein complex involved in the catalysis of the formation of the modified nucleotide 7-methylguanine (at position 46 in certain tRNAs, such as tRNA(phe) and tRNA(met). In yeast, it is a heterotetramer of two subunits, Trm8 (catalytic) and Trm82 (WD repeat).


posterior tibial vein

A vein of the lower limb carries blood from the posterior compartment and plantar surface of the foot to the popliteal vein which it forms when it joins with the anterior tibial vein. Like most deep veins, the posterior tibial vein is accompanied by an artery of the same name, the posterior tibial artery, along its course. [WP,unvetted].


epithelium of lateral semicircular canal

An epithelium that is part of a lateral semicircular canal [Automatically generated definition].


alpha6-beta1 integrin-CYR61 complex

A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.


granulocyte macrophage colony-stimulating factor receptor complex

The heterodimeric receptor for granulocyte macrophage colony-stimulating factor.


violet gland

The violet gland or supracaudal gland is an important gland located on the upper surface of the tail of certain mammals, including European badgers and canids such as foxes, wolves the domestic dog, as well as the domestic cat. It is used for intra species signalling, scent marking, and contributes to the strong odor of foxes in particular.


alpha4-beta1 integrin-CD53 complex

A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.


inferior parathyroid epithelium

An epithelium that is part of a inferior parathyroid gland.


posterior auricular artery

The posterior auricular artery is a small artery and arises from the external carotid artery, above the Digastric muscle and Stylohyoid muscle, opposite the apex of the styloid process. It ascends posteriorly beneath the parotid gland, along the styloid process of the temporal bone, between the cartilage of the ear and the mastoid process of the temporal bone along the lateral side of the head. The posterior auricular artery supplies blood to the scalp posterior to the auricle and to the auricle itself.


vaginal vein

One the veins that drains the vaginal venous plexus, into the hypogastric veins. [WP,modified].


visceral mesothelium

Mesothelium that covers the internal organs is called visceral mesothelium.


U4atac/U6atac x U5 tri-snRNP complex

A spliceosomal snRNP complex that is formed by the association of the U4atac/U6atac and U5 snRNPs.


outer epithelial layer of tympanic membrane

A portion of the external acoustic meatus epithelium which makes up the outer (cuticular) layer of the tympanic membrane.


pancreaticosplenic lymph node

Lymph nodes of the pancreatic tail and spleen, receiving afferents from both organs plus the greater curvature of the stomach; they drain to the celiac lymph nodes.


capillary of anorectum

A capillary that is part of the anorectum.


respiratory system capillary

A capillary that is part of a respiratory system [Automatically generated definition].


thoracic cavity blood vessel

A blood vessel that is part of a thoracic cavity [Automatically generated definition].


SCF-Ctf13 ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.


Descemet's membrane

biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP].


integrin alphaX-beta2 complex

An integrin complex that comprises one alphaX subunit and one beta2 subunit.


collagen type VIII trimer

A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.


SCF-Cdc4 ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.


primordial ovarian follicle

Primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles.


plastid small ribosomal subunit

The smaller of the two subunits of a plastid ribosome.


DPS complex

A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22.


gastric vein

A laterally paired vein that drains blood away from the lesser curvature of the stomach.


temporal vein

Any of the veins draining the temporal region.


mesentery of jejunum

A mesentery that is part of a jejunum [Automatically generated definition].


kidney collecting duct epithelium

The simple cuboidal epithelium lining the lumen of kidney collecting ducts.


alpha6-beta4 integrin-CD151 complex

A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.


high endothelial venule of lymph node

A high endothelial venule that is part of a of lymph node.


respiratory system venule

A venule that is part of a respiratory system [Automatically generated definition].


IscS-TusA complex

A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.


renal cortex artery

An artery that supplies the renal cortex.


collagen type XVI trimer

A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.


dystrobrevin complex

A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.


EMILIN complex

Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures.


apocrine sweat gland

Apocrine sweat glands are sweat glands composed of a coiled secretory portion located at the junction of the dermis and subcutaneous fat, from which a straight portion inserts and secretes into the infundibular portion of the hair follicle. The ducts of apocrine glands open into the canals of hair follicles. The stimulus for the secretion of apocrine sweat glands is adrenaline, which is a hormone carried in the blood[WP].


subsegmental bronchus

Branch of conducting airway between a segmental bronchus and a preterminal bronchiole.


parotid gland intralobular duct

Any of the tubular canals of the parotid gland located within the parenchymal (secretory) tissue i.e. within lobules; both intercalated and striated (secretory) ducts are intralobular ducts.


The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive[GO].


NuA3b histone acetyltransferase complex

A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.


somite 14

Undifferentiated mesodermal component of early trunk segment 14 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


muscular artery

Part of the external carotid which delivers blood to the mm rectus cervicis and interhyoideus posterior.


anterior chamber epithelium

An epithelium that is part of a anterior chamber of eyeball.


respiratory system blood vessel

A blood vessel that is part of a respiratory system [Automatically generated definition].


parametrium

The subserous connective tissue of the pelvic floor of the supracervical portion of the uterus. The parametrium extends laterally between the layers of the broad ligament.


PSI associated light-harvesting complex I

Protein-pigment complex associated with photosystem I.


deep facial vein

The anterior facial vein receives a branch of considerable size, the deep facial vein, from the pterygoid venous plexus.


alphaIIb-beta3 integrin-talin complex

A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.


kidney arterial blood vessel

An arterial blood vessel that is part of a kidney [Automatically generated definition].


heterotetrameric decaprenyl diphosphate synthase complex

A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1.


thymic artery

A vein that supplies blood to the thymus.


cytoplasmic origin of replication recognition complex

A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm.


Kv4.2-DPP6 channel complex

A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.


chloroplast ribosome

A ribosome contained within a chloroplast.


right renal vein

A renal vein that drains the right kidney.


endopeptidase complex

A protein complex which is capable of endopeptidase activity.


capsule of temporomandibular joint

The articular capsule (capsular ligament) is a thin, loose envelope, attached above to the circumference of the mandibular fossa and the articular tubercle immediately in front; below, to the neck of the condyle of the mandible.


telencephalon dura mater

A dura mater that is part of a telencephalon [Automatically generated definition].


creatine kinase complex

A protein complex having creatine kinase activity.


subcutaneous lymph node

A lymph node that is part of a hypodermis.


actin capping protein of dynactin complex

A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex.


Harderian gland

The Harderian gland is an anterior orbital gland usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species[GO].


external iliac lymph node

A lymph node located along the external iliac artery.


stomach squamous epithelium

A squamous epithelium that is part of a stomach.


alpha2-beta1 integrin-CD47 complex

A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.


alpha4-beta1 integrin-CD47 complex

A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.


low-density lipoprotein receptor complex

A plasma membrane protein complex capable of low-density lipoprotein particle receptor activity. It may also bind xenobiotic toxins and deliver them into the cell via endocytosis. While most substrates get degraded via the endosome the receptor is recycled to the plasma membrane. It may also act as a transducer of intracellular signal pathways and often acts in corporation with other cell-surface receptors.


condensed chromatin of inactivated sex chromosome

A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation.


protein-containing complex

A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.


peritoneal mesentery

Mesentery that is located in the peritoneum.


layer of synovial tissue

A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO].


cytosolic proteasome core complex

The core complex of a proteasome located in the cytosol of a cell.


skin of abdomen

A zone of skin that is part of an abdomen [Automatically generated definition].


eyelid blood vessel

A blood vessel that is part of a eyelid [Automatically generated definition].


mesothelium

Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri).


nephron epithelium

The nephron epithelium is a tissue that covers the surface of a nephron.


protein-DNA ISRE complex

A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA.


respiratory system artery

An artery that is part of a respiratory system [Automatically generated definition].


eyelid epithelium

An epithelium that is part of an eyelid [Automatically generated definition].


parotid main excretory duct

The main excretory tubular canal that connects the parotid gland and the buccal mucosa and secretes a serous saliva into the vestibule of the oral cavity; it arises from the anterior surface of the gland, traversing the masseter muscle; the duct then pierces the buccinator muscle, moving medially, and opens out into the oral cavity near the second upper molar; saliva produced by acinar secretory cells in the glandular body flows sequentially through the intercalated ducts, striated ducts, and excretory ducts.


Isw1a complex

An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.


serosa of large intestine

A serous membrane that is part of a large intestine [Automatically generated definition].


activated SUMO-E1 ligase complex

A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins.


synchondrosis

Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA].


protein complex involved in cell-cell adhesion

Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.


M/G1 phase-specific MADS box-forkhead transcription factor complex

A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.


plantar digital vein

The plantar digital veins arise from plexuses on the plantar surfaces of the digits, and, after sending intercapitular veins to join the dorsal digital veins, unite to form four metatarsal veins.


epithelium of terminal part of digestive tract

Epithelium lining the distalmost portion of the digestive tract.


visceral pre-aortic lymph node

Intestinal lymph node located anterior to aorta.


photosystem II antenna complex

The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).


phosphatidylinositol 3-kinase complex, class II

A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.


base of crypt of Lieberkuhn

The basal portion (further from lumen) of an intestinal crypt. Contains multipotent stem cells. Stem cells in the crypts divide to form daughter cells. One daughter cell from each stem cell division is retained as a stem cell. The other becomes committed to differentiate along one of four pathways to become an enterocyte, enteroendocrine cell, goblet cell or Paneth cell.


subcommissural organ

The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted].


Fc-gamma receptor III complex

A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.


brain ependyma

The ependymal cell layer that lines the brain ventricles.


ERMES complex

A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.


cytosolic oxoglutarate dehydrogenase complex

A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).


plasma membrane proton-transporting V-type ATPase complex

A proton-transporting two-sector ATPase complex found in the plasma membrane.


fatty acid elongase complex

A tetrameric complex of four different subunits which catalyzes the elongation of a fatty acid chain 2 carbon units at a time in the synthesis of very long chain fatty acids.


annulus fibrosus disci intervertebralis

The ring of fibrocartilage and fibrous tissue forming the circumference of the intervertebral disc; surrounds the nucleus pulposus, which is prone to herniation when the annulus fibrosus is compromised.


vertebral vein

The vertebral vein is formed in the suboccipital triangle, from numerous small tributaries which spring from the internal vertebral venous plexuses and issue from the vertebral canal above the posterior arch of the atlas. They unite with small veins from the deep muscles at the upper part of the back of the neck, and form a vessel which enters the foramen in the transverse process of the atlas, and descends, forming a dense plexus around the vertebral artery, in the canal formed by the foramina transversaria of the cervical vertebrae. This plexus ends in a single trunk, which emerges from the foramen transversarium of the sixth cervical vertebra, and opens at the root of the neck into the back part of the innominate vein near its origin, its mouth being guarded by a pair of valves. On the right side, it crosses the first part of the subclavian artery. [WP,unvetted].


ovary growing follicle

An ovarian follicle undergoing maturation.


venule of anorectum

A venule that is located in the anorectum.


epithelium of footplate

An epithelium that is part of a footplate.


inferior cerebral vein

The inferior cerebral veins, of small size, drain the under surfaces of the hemispheres. Those on the orbital surface of the frontal lobe join the superior cerebral veins, and through these open into the superior sagittal sinus. Those of the temporal lobe anastomose with the middle cerebral and basal veins, and join the cavernous, sphenoparietal, and superior petrosal sinuses. [WP,unvetted].


platelet-derived growth factor receptor-ligand complex

A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerization and activation. PDGFs are involved in a wide variety of signaling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes.


submandibular duct

The duct of the submadibular gland that opens at the sublingual papilla near the frenulum of the tongue.


optic eminence surface ectoderm

An external ectoderm that is part of a optic eminence [Automatically generated definition].


taurine dioxygenase complex

A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD.


inferior cerebellar vein

The inferior cerebellar veins are of large size, end in the transverse, superior petrosal, and occipital sinuses. [WP,unvetted].


plasma membrane proton-transporting ATP synthase complex, coupling factor F(o)

All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins.


intersomitic vein

The vein that sprouts from the posterior cardinal vein, growing dorsally between the somites, and then joining, and draining the dorsal longitudinal anastomosing vessel.


differentiating neuroepithelium

A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells.


Ssh1 translocon complex

A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.


secretory IgA immunoglobulin complex

A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.


eRF1 methyltransferase complex

A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.


deep external pudendal artery

The deep external pudendal artery (deep external pudic artery), more deeply seated than the superficial external pudendal artery, passes medialward across the Pectineus and the Adductor longus muscles; it is covered by the fascia lata, which it pierces at the medial side of the thigh, and is distributed, in the male, to the integument of the scrotum and perineum, in the female to the labium majus; its branches anastomose with the scrotal (or labial) branches of the perineal artery.


interleukin-10 receptor complex

A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors.


mammary gland myoepithelium

The outer cell layer of the mammary gland epithelium bilayer which is located basal to the luminal (secretory) cells and adjacent to the basement membrane.


scalp

The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendonous galea aponeurotica; Loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL).


interleukin-20 receptor complex

A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits.


artery of appendix

An artery that is part of a vermiform appendix.


extraembryonic umbilical vein

Extraembryonic part of the vein passing through the umbilical cord to the fetus and returning the purified and nutrient blood from the placenta.


SCF-Skp2 ubiquitin ligase complex

An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.


Smp focus

A DNA-binding ribonucleoprotein complex that contains a lncRNA complementary to the bound chromosomal locus and is involved in the tethering homologous chromosomes together during chromosome pairing at meiotic prophase I.


nephron tubule basement membrane

A basement membrane that is part of a nephron tubule.


mesoderm blood island

A blood island that is part of a mesoderm.


migrating epithelium

An epithelium that extends its surface area by peripheral movement.


testicular artery

One of a pair of arteries that is a branch of the abdominal aorta that supplies blood to a male gonad.


posterior ciliary vein

The outer layer of the choroid (lamina vasculosa) consists, in part, of the larger branches of the short ciliary arteries which run forward between the veins, before they bend inward to end in the capillaries, but is formed principally of veins, named, from their arrangement, the vorticose veins. They converge to four or five equidistant trunks, which pierce the sclera about midway between the sclero-corneal junction and the entrance of the optic nerve. They drain uveal tract.


middle thyroid vein

The middle thyroid vein collects the blood from the lower part of the thyroid gland, and after being joined by some veins from the larynx and trachea, ends in the lower part of the internal jugular vein.


synapsis initiation complex

A SUMO-E3 ligase complex capable of promoting synapsis, the meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase.


hindbrain arachnoid mater

An arachnoid mater that is part of a hindbrain [Automatically generated definition].


skin sebaceous gland

A holocrine gland of the dermis that secretes sebum into hair follicles.


right hepatic vein

A hepatic vein that is part of a right lobe of liver.


activating signal cointegrator 1 complex

A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3.


epithelial vesicle

A closed epithelium with a lumen.


somite 10

Undifferentiated mesodermal component of early trunk segment 10 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


merocrine gland

An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged.


metanephric macula densa

The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus[GO].


nodal receptor complex

A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell.


pelvic sucking disc

An adhesive disk modified from the pelvic fins in, for example, clingfishes (Gobiesocidae), gobies (Gobiidae) and snailfishes (Liparidae).


blood vessel of tympanic cavity

A blood vessel that is part of a tympanic cavity [Automatically generated definition].


epithelial bud

A bud is a protrusion that forms from an epithelial sheet by localized folding.


laminin-12 complex

A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.


esBAF complex

An embryonic stem cell-specific SWI/SNF-type complex that contains eight or nine proteins, including both conserved (core) and nonconserved components; contains the ATPase product of either the SMARCA4/BAF190A/BRG1 gene, the mammalian ortholog of the yeast SNF2 gene, or an ortholog thereof. Compared to many other BAF complexes never contains ACTL6B/BAF53B, ARID1B/BAF250B, SMARCA2/BRM, SMARCC2/BAF170 or SMARCD3/BAF60C but contains PHF10/BAF45A, DPF2/BAF45D and possibly one of BCL7A/B/C.


collagen type XVIII trimer

A collagen homotrimer of alpha1(XVIII) chains.


anterior talofibular ligament

The anterior talofibular ligament is a ligament in the ankle. It passes from the anterior margin of the fibular malleolus, anteriorly and medially, to the talus bone, in front of its lateral articular facet. It is one of the lateral ligaments of the ankle and prevents the foot from sliding forward in relation to the shin.


iris epithelium

An epithelium that is part of a iris [Automatically generated definition].


intercostal vein

The intercostal veins are a group of veins which drain the area between the ribs.


RNA polymerase I upstream activating factor complex

A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p.


suprarenal vein

A vein that drains the adrenal gland.


nutrient foramen vein

A vein or veins draining a bone and emerging from a nutrient foramen.


tonsil epithelium

The epithelium that forms the surface of the tonsil dips into the underlying connective tissue in numerous places, forming crypts kown as tonsillar crypts. Stratified squamous epithelium, that may be heavily infiltrated by lymphocytes. Epithelial cells are present in the germinal as well as in the periphery of the nodule.


serosa of uterus

Outer serosa layer of the uterus.


venule of appendix

A venule located in the vermiform appendix.


arcuate artery of foot

The arcuate artery of the foot (metatarsal artery) arises a little anterior to the lateral tarsal artery; it passes lateralward, over the bases of the metatarsal bones, beneath the tendons of the Extensor digitorum brevis, its direction being influenced by its point of origin; and its anastomoses with the lateral tarsal and lateral plantar arteries. This vessel gives off the second, third, and fourth dorsal metatarsal arteries. It is not present in all individuals.


deep fascia

Deep fascia (or 'investing fascia') is a layer of fascia which can surround individual muscles, and divide groups of muscles into compartments. This is the dense fibrous connective tissue that interpenetrates and surrounds the muscles, bones, nerves and blood vessels of the body. It provides connection and communication in the form of aponeuroses, ligaments, tendons, retinacula, joint capsules, and septa. The deep fasciae envelop all bone; cartilage, and blood vessels and become specialized in muscles and nerves. The high density of collagen fibers is what gives the deep fascia its strength and integrity. The amount of elastin fiber determines how much extensibility and resilience it will have.


Cbf1-Met4-Met28 complex

A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.


nucleotide-excision repair factor 2 complex

One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.


epithelium of nasal septum

An epithelium that is part of a nasal septum [Automatically generated definition].


interopercular-mandibular ligament

Interopercular-mandibular ligament is a ligament that connects the interopercle to an element of the lower jaw, typically the retroarticular.


magnesium-dependent protein serine/threonine phosphatase complex

An intracellular enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase.


midbrain pia mater

A pia mater that is part of a midbrain [Automatically generated definition].


alpha9-beta1 integrin-VEGF-C complex

A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.


lateral marginal vein

A continuation of the Dorsal venous arch of the foot and is the origin of the short saphenous vein.


IgM immunoglobulin complex, circulating

A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.


A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.


Holliday junction helicase complex

A DNA helicase complex found at Holliday junctions where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.


NarGHI complex

A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit.


infrapatellar fat pad

The infrapatellar fat pad, also known as Hoffa's fat pad, is a cylindrical piece of fat that is situated under and behind the patella bone within the knee.


iron-sulfur cluster transfer complex

A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor).


3-methylcrotonyl-CoA carboxylase complex, mitochondrial

A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.


lateral pretrosal artery

Part of the internal carotid which supplies blood to the ear and branches to two additional arteries.


alpha3-beta1 integrin-CD63 complex

A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.


G protein-coupled receptor homodimeric complex

A protein complex that contains two G protein-coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.


myosin phosphatase complex

An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin. Composed of a PP1 catalytic subunit (PP1c/PPP1CB) and a myosin phosphatase targeting subunit (MYPT1/PPP1R12A).


zygomatico-orbital artery

The middle temporal artery occasionally gives off a zygomatico-orbital branch, which runs along the upper border of the zygomatic arch, between the two layers of the temporal fascia, to the lateral angle of the orbit. This branch, which may arise directly from the superficial temporal artery, supplies the Orbicularis oculi, and anastomoses with the lacrimal and palpebral branches of the ophthalmic artery.


cytosolic proteasome regulatory particle, lid subcomplex

The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.


anal canal epithelium

An epithelium that is part of a anal canal.


alphaM-beta2 integrin-CD63 complex

A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.


inner ear epithelium

The epithelial cell layer containing the sensory hair cells and their associated sensory nerve terminals.


capillary of small intestine

A capillary that is part of a small intestine.


m-AAA complex

Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria.


cerebral vein

The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted].


alphav-beta3 integrin-PKCalpha complex

A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha.


sinusoid

Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP].


mitochondrial proton-transporting ATP synthase, central stalk

One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.


intercostal ligament

Ligament that connects one rib to another.


alphaV-beta3 integrin-EGFR complex

A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.


IgG immunoglobulin complex, circulating

A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


BIM-BCL-2 complex

A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.


retroperitoneal lymph node

A lymph node located in the retroperitoneal space.


abdominal aorta artery

An artery that originates from the abdominal aorta.


nucleotide-excision repair factor 3 complex

One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p).


extrahepatic duct

Bile duct that collects from the intrahepatic ducts and feeds into the common bile duct.


right pulmonary vein

Vein that drains right lung and returns blood to the heart.


alphaV-beta3 integrin-gelsolin complex

A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.


A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.


distal straight tubule macula densa

A macula densa that is part of an ascending limb of loop of Henle [Automatically generated definition].


A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).


oviduct epithelium

An epithelium that is part of a oviduct [Automatically generated definition].


exocrine gland of integumental system

An exocrine gland that is part of a integumental system.


capillary blood

A blood that is part of a capillary.


cysteine synthase complex

Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A.


deep cerebral vein

The deep cerebral veins are a group of veins in the head. This group includes the superior thalamostriate vein.


A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.


alphav-beta3 integrin-HMGB1 complex

A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein.


transforming growth factor beta activated kinase 1 complex

A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits).


Bre1-Rad6 ubiquitin ligase complex

A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis.


upper eyelid epithelium

An epithelium that is part of an upper eyelid [Automatically generated definition].


laminin-8 complex

A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.


marginal venous sinus

A paired dural venous sinus at the rim of the foramen magnum.


somite 11

Undifferentiated mesodermal component of early trunk segment 11 or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


intraorbital lacrimal gland

A lacrimal gland located superficially at the lateral canthus, where both the lacrimal gland and Harderian gland ducts open.


non-keratinized stratified squamous epithelium

Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus.


myosin XI complex

A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.


Jacobson's vein

Either of a pair of veins which receives many small vesicles from the kidney and collects blood from the oviducal vein.


cytosolic isocitrate dehydrogenase complex (NAD+)

Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity.


dihydropyrimidine dehydrogenase (NAD+) complex

A heteromultimeric complex capable of dihydropyrimidine dehydrogenase (NAD+); in E. coli, composed of PreA and PreT.


lateral thoracic vein

The lateral thoracic vein is a tributary of the axillary vein. It runs with the lateral thoracic artery and drains the serratus ventralis muscle and the Pectoralis major muscle. Normally, the thoracoepigastric vein exists between this vein and superficial epigastric vein (a tributary of femoral vein), to act as a shunt for blood if the portal system (through the liver) develops hypertension or a blockage. [WP,unvetted].


ciliated columnar epithelium

Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA].


lower jaw incisor epithelium

A dental epithelium that is part of a lower jaw incisor.


skin of elbow

A zone of skin that is part of a elbow [Automatically generated definition].


heart blood vessel

A blood vessel that is part of a heart [Automatically generated definition].


inferior pancreaticoduodenal vein

A blood vessel running parallel to the inferior pancreatico-duodenal artery that drains blood from the pancreas and duodenum into the splenic vein.


homodimeric decaprenyl diphosphate synthase complex

A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.


mesonephric nephron epithelium

The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros[GO].


capillary

Any of the smallest blood vessels connecting arterioles with venules.


epithelium of large intestine

An epithelium that is part of a large intestine [Automatically generated definition].


nuclear proteasome regulatory particle

The regulatory subcomplex of a proteasome located in the nucleus of a cell.


ciliated columnar oviduct epithelium

A ciliated columnar epithelium that is part of a oviduct.


arterial blood vessel

A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta.


phrenic vein

The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins.


larynx mucous gland

A mucous gland that is part of a larynx [Automatically generated definition].


greater omentum mesothelium

A mesothelium that is part of a greater omentum.


cytosolic alpha-ketoglutarate dehydrogenase complex

Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity.


DNA helicase A complex

A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction.


swim bladder artery

An elaborate set of vessels that branche off caudally from the anterior mesenteric artery just after the dorsal aorta. The SBA vascular loops are located on the ventral side of the swim bladder. Isogai et al. 2001.


histone H3-containing nucleosome

A complex comprised of DNA wound around a multisubunit core and associated proteins containing the histone H3, which forms the primary packing unit of DNA into higher order structures.


retina blood vessel

A blood vessel that is part of a retina [Automatically generated definition].


MIB complex

A mitochondrial intermembrane space bridging complex consisting of components of the MICOS complex in the inner mitochondrial membrane, the SAM complex in the outer membrane, a conserved DNAJ protein (human DNAJC11) and Metaxin 1.


Complex that possesses imidazoleglycerol-phosphate synthase activity.


pararenal fat

The paranephric body (or paranephric fat or pararenal fat) is collection of adipose tissue located superficial to the renal fascia. The perirenal fat, or adipose capsule of kidney, is deep to the renal fascia but superficial to the renal capsule.


base of crypt of Lieberkuhn of large intestine

A base of crypt of Lieberkuhn that is part of a large intestine.


fascia lata

The deep fascia of the thigh. [WP,unvetted].


fundic gastric gland

The fundus glands (or fundic glands, or gastric glands) are found in the body and fundus of the stomach. They are simple tubes, two or more of which open into a single duct.


A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.


endoderm of midgut

An endoderm that is part of a midgut [Automatically generated definition].


renal portal vein

A portal vein that empties into capillaries within the kidneys.


left subcostal vein

A vein that extends along the bottom of the twelfth rib on the left side of the body.


vein of upper lip

The inferior labial vein is the vein receiving blood from the upper lip.


Wpl/Pds5 cohesin loading/unloading complex

A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.


hyaloid vessel

A blood vessel that is associated with the lens. In mammals, this is transient and normally nourishes the retina, immature lens and primary vitreous of the developing eye.


upper leg epithelium

An epithelium that is part of a hindlimb stylopod [Automatically generated definition].


coronary sinus

The short trunk that recieves most of the cardiac veins carrying the blood from the myocardium and delivers it to the right atrium, with the sinoatrial connection occurring between the inferior vena cava and the atrioventricular orifice.


non-mineralized hyaline cartilage tissue

Hyaline cartilage tissue that is not mineralized.


medial-nasal process ectoderm

An ectoderm that is part of a medial nasal prominence [Automatically generated definition].


U11/U12 snRNP

A ribonucleoprotein complex that is formed by the association of the U11 and U12 small nuclear ribonucleoproteins.


transmembrane collagen trimer

Any collagen trimer that passes through a lipid bilayer membrane.


facial lymph node

Any of the lymph nodes that are part of a face.


appendicular artery

An artery that commonly arises from the terminal branch of the ileocolic artery, or less commonly from the posterior cecal artery or an ileal artery.[1][2] It descends behind the termination of the ileum and enters the mesoappendix of the vermiform appendix. It runs near the free margin of the mesoappendix and ends in branches which supply the appendix.


vein of trabecular bone

A portion of vein that is part of a trabecular bone tissue [Automatically generated definition].


phospholamban complex

A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.


lipid tube

A macromolecular complex that contains a tube of lipid surrounded by a protein coat.


epithelium of lens

A layer of epithelial cells that is part of the eye.


basilic vein

A superficial vein of the upper limb that drain parts of manus and forearm.


gastric lymph node

A lymph node along the left gastric artery or greater omentum.


nitric-oxide synthase complex

A protein complex which is capable of nitric-oxide synthase activity.


bacterial pre-replicative complex

A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.


alpha4-beta1 integrin-CD81 complex

A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.


skeletal muscle endomysium

Reticular tissue which surrounds a skeletal muscle cell.


artery of lower lip

The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery.


integrin alpha4-beta1 complex

An integrin complex that comprises one alpha4 subunit and one beta1 subunit.


alpha9-beta1 integrin-VEGF-D complex

A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.


proper hepatic artery

The hepatic artery proper (also proper hepatic artery), arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. The hepatic artery proper gives off a small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently gives off the cystic artery, which feeds the gallbladder, before bifurcating into the right and left hepatic arteries. Of note, the right and left hepatic arteries may demonstrate variant anatomy. A replaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a replaced left hepatic artery may arise from the left gastric artery.


plastid large ribosomal subunit

The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).


ankyrin-1 complex

A complex composed of ANK1, RHCE, RHAG, SLC4A1, EPB42, GYPA, GYPB and AQP1, that functions in the stability and shape of the erythrocyte membrane in human.


lymph node of inferior pulmonary ligament


pelvic lymph node

Any lymph node within the abdominal pelvic region.


skin of pes

A zone of skin that is part of a pes [Automatically generated definition].


hemiazygos vein

The hemiazygos vein (vena azygos minor inferior) is a vein running superiorly in the lower thoracic region, just to the left side of the vertebral column.


pre-primosome complex

Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component.


annulus fibrosus

A ring of fibrous or fibrocartilaginous tissue (as of an intervertebral disk or surrounding an orifice of the heart).


silver ion transmembrane transporter complex

A protein complex which is capable of silver ion transmembrane transporter activity.


ERBB4-ERBB4 complex

A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4).


RNA polymerase IV complex

RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex.


alphaV-beta3 integrin-tumstatin complex

A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.


ATP-binding cassette (ABC) transporter complex, integrated substrate binding

A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a half transporter. Two half-transporters come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.


prevertebral cervical fascia

The prevertebral fascia (or prevertebral layer of cervical fascia) is a fascia in the neck.


dorsal metatarsal vein

The dorsal metatarsal veins are veins which drain the metatarsus of the foot. [WP,unvetted].


manual digit 3 epithelium

An epithelium that is part of a manual digit 3.


A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.


left hepatic artery

A hepatic artery that is part of a left lobe of liver.


potassium ion-transporting ATPase complex

Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex.


jejunal vein

A tributary of the superior mesenteric vein that drains the jejunum.


hepatic duct

Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion).


epithelium of crypt of Lieberkuhn of small intestine


Ddb1-Wdr21 complex

A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.


Shc-Grb2-Sos complex

A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.


perimysium

The fibrous sheath enveloping each of the primary bundles of skeletal muscle fibers.


lysosomal proton-transporting V-type ATPase, V1 domain

The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.


hyponychium

Epithelium located beneath the nail plate at the junction between the free edge and the skin of the fingertip. It forms a seal that protects the nail bed.


i-AAA complex

Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.


IgM immunoglobulin complex

A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.


posterior ethmoidal artery

The posterior ethmoidal artery is an artery of the head. It is smaller than the anterior ethmoidal artery, branches off from the ophthalmic artery when it reaches the medial wall of the orbit.


photosystem I reaction center

A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin.


hemipenial mucuous gland

A gland within the hemipenial sheath that provides lubrication for the hemipenis.


mediastinal lymph node

A lymph node that is part of a mediastinum. Each consists of several lymph node groups, especially along the trachea (5 groups), along the esophagus and between the lung and the diaphragm. In the mediastinal lymph nodes arises lymphatic ducts, which draines the lymph to the left subclavian vein (to the venous angle in the confluence of the subclavian and deep jugular veins). The mediastinal lymph nodes along the esophagus are in tight connection with the abdominal lymph nodes along the esophagus and the stomach. That fact facilitates spreading of tumors cells through these lymphatics in cases of cancers of the stomach and particularly of the esophagus. Through the mediastinum, the main lymphatic drainage from the abdominal organs goes via the thoracic duct (ductus thoracicus), which drains majority of the lymph from the abdomen to the above mentioned left venous angle.


epithelial sheet

An epithelial sheet is a flat surface consisting of closely packed epithelial cells.


maltose transport complex

Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK.


endothelial blood brain barrier

A blood brain barrier that is composed of endothelial cells.


gonadal vein

In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted].


plastid pyruvate dehydrogenase complex

Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria.


hepatic sinusoid of left of lobe of liver

A hepatic sinusoid that is part of a left lobe of liver.


ecto-epithelium

Epithelium composed of cells that develops from the ectoderm[FMA,modified].


lens vesicle epithelium

An epithelium that is part of a lens vesicle.


endocardium of right ventricle

Any endocardium that is part of the right ventricle of the heart.


lateral nasal gland

Any of the lateral nasal glands (the largest nasal secretory glands in rodents) which surround the maxillary sinus located in the lateral wall adjacent to each nasal passage and are characterized by cytologic features similar to those described for the major serous salivary glands; secretory contents of the LNG drain into the nasal vestibule; the LNG is a major site for the synthesis and secretion of odorant-binding proteins that serve as odorant carriers in nasal mucus; it also, synthesizes large amounts of immunoglobulin A, which is important for immune defense of the upper respiratory tract, and testosterone and salivary androgen-binding proteins, which are likely important in olfaction and reproductive behavior.


kidney epithelium

The cellular avascular layer of the kidney luminar surfaces.


labial gland

The labial gland is one of the minor salivary glands, located mainly under the mucosal epithelium of the upper and lower lip and within the orbicularis oris muscle fibers. The labial gland secrete mucous and serous substances to maintain oral health. In particular, the inferior labial gland not only promotes moisturization in the oral cavity but also secretes substances with antibacterial effects.


cephalic neural fold

The elevated margins of the neural groove that are located in the future cephalic region of the embryo.


gastric gland

The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin.


epithelium of incisor

An epithelium that is part of a incisor tooth [Automatically generated definition].


cavernous artery

Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses.


Pip2-Oaf1 complex

A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins.


median sacral artery

The median sacral artery (or middle sacral artery) is a small vessel, which arises from the back of the aorta, a little above its bifurcation. It descends in the middle line in front of the fourth and fifth lumbar vertebræ, the sacrum and coccyx, and ends in the glomus coccygeum (coccygeal gland). From it, minute branches are said to pass to the posterior surface of the rectum. On the last lumbar vertebra it anastomoses with the lumbar branch of the iliolumbar artery; in front of the sacrum it anastomoses with the lateral sacral arteries, and sends offsets into the anterior sacral foramina. It is crossed by the left common iliac vein, and is accompanied by a pair of venæ comitantes; these unite to form a single vessel, which opens into the left common iliac vein.


Kv4.2-Kv4.3 channel complex

A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3.


A protein complex that is involved in the transfer of the second mannose to the glycosylphosphatidylinositol (GPI) during GPI precursor assembly. In yeast S. cerevisiae this complex consists of GPI18p and PGA1p.


left extraembryonic umbilical vein

An extraembryonic umbilical vein that is in_the_left_side_of a multicellular organism.


superoxide dismutase complex

A protein complex which is capable of superoxide dismutase activity.


endo-epithelium

Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA].


vacuolar HOPS complex

Any HOPS complex that is part of a vacuolar membrane.


enveloping layer of ectoderm

Outermost layer of cells surrounding the embryo.


forebrain neural plate

A neural plate that develops_from a future forebrain.


pharyngeal arch artery 4

The vessels formed within the fourth pair of branchial arches in embryogenesis.


renal lymph node

A lymph node that is located in a kidney [Automatically generated definition].


enzyme IIA-maltose transporter complex

A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter.


cytosolic tricarboxylic acid cycle enzyme complex

Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle.


superficial lymph node

A lymph node that is located close to the surface.


mesentery of rectum

A mesentery that is part of a rectum [Automatically generated definition].


thyroid follicle epithelium

An epithelium that is part of a thyroid follicle.


dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex

A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p.


mesentery of stomach

The portion of the primitive mesentery that encloses the stomach; from its dorsal sheet, the greater omentum develops, and from its ventral sheet, the lesser omentum.


venule

One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins.


integrin alpha5-beta1 complex

An integrin complex that comprises one alpha5 subunit and one beta1 subunit.


galectin complex

A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.


laminin-4 complex

A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.


external soft tissue zone

A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures.


trunk somite

A somite that is part of a trunk.


mammary branch of internal thoracic artery


eukaryotic 80S initiation complex

A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.


BAX complex

An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators.


clathrin coat of synaptic vesicle

A clathrin coat found on a synaptic vesicle.


acetolactate synthase complex

A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.


translation initiation complex

A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.


EFF-1 complex

A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer.


orbital fat pad

A fat pad that is part of a orbital region.


lacrimal vein

A vein that drains a lacrimal gland.


foregut epithelium

An epithelium that is part of a foregut.


Harderian gland epithelium

An epithelium that is part of a Harderian gland [Automatically generated definition].


upper arm blood vessel

A blood vessel that is part of a forelimb stylopod [Automatically generated definition].


somite 30

Posteriormost undifferentiated mesodermal component of early tail segment or metamere, derived from paraxial mesoderm; forms the myotome, sclerotome and perhaps dermatome. Kimmel et al, 1995.


epididymal fat pad

Encapsulated adipose tissue associated with the epididymis.