cellular response to methylglyoxal

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.


negative regulation of hair follicle cell proliferation

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation.


regulation of planar cell polarity pathway involved in ventricular septum morphogenesis

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.


diphenyl ether 1,2-dioxygenase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+.


positive regulation of neural retina development

Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.


establishment of protein localization to spindle pole body

The directed movement of a protein to a specific location at the spindle pole body.


negative regulation of adipose tissue development

Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.


benzoyl acetate-CoA ligase activity

Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.


negative regulation of cellodextrin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process.


positive regulation of sporangium development

Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.


epithelial cell morphogenesis involved in gastrulation

The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.


basidium development

The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.


establishment of planar polarity of larval imaginal disc epithelium

Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates.


positive regulation of long-day photoperiodism, flowering

Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.


class II DNA-(apurinic or apyrimidinic site) endonuclease activity

Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.


microsporocyte differentiation

The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.


cellular response to oxidopamine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.


regulation of cumulus cell differentiation

Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation.


diestrus

The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum.


compound eye photoreceptor development

The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.


Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.


mRNA dihydrouridine synthase activity

Catalysis of the reaction: mRNA-uracil + NAD(P)+ = mRNA-dihydrouridine + NAD(P)H+ + H+.


ganglion structural organization

The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.


taurine dioxygenase activity

Catalysis of the reaction: 2-oxoglutarate + O2 + taurine = aminoacetaldehyde + CO2 + succinate + sulfite.


plant-type cell wall organization

A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana.


karyogamy

The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.


regulation of gluconate transmembrane transport

Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.


plasmacytoid dendritic cell cytokine production

Any process that contributes to cytokine production by a plasmacytoid dendritic cell.


protein N-linked glucosylation via asparagine

A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue.


box C/D RNA metabolic process

The chemical reactions and pathways involving box C/D type small nucleolar RNA.


4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity

Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A.


D-alanine [D-alanyl carrier protein] ligase activity

Catalysis of the ATP-dependent activation of D-alanine and its transfer as a thiol ester to the phosphopantheinyl prosthetic group of a D-alanyl carrier protein, according to the reaction: ATP + D-alanine + a [D-alaninyl carrier protein] = a D-alanyl-[D-alanyl carrier protein] + AMP + diphosphate.


maintenance of vesicle location

Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.


Ran protein signal transduction

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state.


peptidyl-allysine oxidation to 2-aminoadipic acid

The oxidation of allysine to 2-aminoadipic acid.


Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD+ = H+ + NADH + phenanthrene-3,4-diol.


holo-citrate lyase synthase activity

Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase.


response to parasitic plant

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.


sulfolipid metabolic process

The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.


lovastatin nonaketide synthase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H+ + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO2 + 9 CoA + dihydromonacolin L + 6 H2O + 11 NADP+.


negative regulation of choline O-acetyltransferase activity

Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity.


linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity

Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool.


negative regulation of emodin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process.


fosmidomycin transmembrane transporter activity

Enables the transfer of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, from one side of a membrane to the other.


Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.


Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.


deoxyribose-phosphate aldolase activity

Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.


positive regulation of urine volume by pressure natriuresis

An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.


response to pheromone regulating conjugation with mutual genetic exchange

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus regulating the process of conjugation without cellular fusion.


sexual sporulation resulting in formation of a cellular spore

The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.


regulation of growth of unicellular organism as a thread of attached cells

Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.


L-phenylalanine biosynthetic process from chorismate via phenylpyruvate

The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.


ATPase-coupled intramembrane lipid transporter activity

Catalysis of the movement of lipids from one membrane leaflet to the other, driven by ATP hydrolysis. This includes flippases and floppases.


protein localization to T-tubule

A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.


single subunit type RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


positive regulation of cerebellar granule cell migration by calcium

The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration.


Catalysis of the reaction: UDP-alpha-D-glucose(2-) + quercetin 3-O-rhamnoside <=> quercetin 3-O-rhamnoside-7-O-glucoside + UDP.


monomethyl-sulfatase activity

Catalysis of the reaction: H2O + monomethyl sulfate = H+ + methanol + sulfate.


extraction of mislocalized protein from membrane

The removal of a mislocalized protein from a cellular membrane.


negative regulation of maltoheptaose metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process.


Catalysis of the reaction: 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl diphosphate = [1-(2-amino-7-methyl-4-oxo-7,8-dihydro-3H-pteridin-6-yl)]ethyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + diphosphoric acid.


glutaryl-CoA dehydrogenase activity

3-methylbutanoyl-CoA + H+ + oxidized [electron-transfer flavoprotein] = 3-methyl-(2E)-butenoyl-CoA + reduced [electron-transfer flavoprotein].


o-aminophenol oxidase activity

Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O.


kojibiose phosphorylase activity

Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose.


intermediate mesoderm morphogenesis

The process in which the anatomical structures of the intermediate mesoderm are generated and organized.


terrequinone A biosynthetic process

The chemical reactions and pathways resulting in the formation of terrequinone A.


Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H+ + UDP.


response to thiabendazole

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.


3-oxo-palmitate decarboxylase activity

Catalysis of the reaction: 3-oxopalmitic acid + H+ = 2-pentadecanone + carbon dioxide.


fumagillin catabolic process

The chemical reactions and pathways resulting in the breakdown of fumagillin.


His-Purkinje system cell development

The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.


GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine

The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


induction of programmed cell death by hormones

Any process induced by hormones that directly activates any of the steps required for programmed cell death.


Catalysis of the reaction: UDP-alpha-D-glucose + kinetin <=> H+ + kinetin-7-N-glucoside + UDP.


histone H3K36me2/H3K36me3 demethylase activity

Catalysis of the removal of a methyl group from a tri- or a dimethyl-lysine residue at position 36 of the histone H3 protein. This is a dioxygenase reaction that is dependent on Fe(II) and 2-oxoglutarate.


sulfoacetaldehyde lyase activity

Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite.


glutathione oxidase activity

Catalysis of the reaction: 2 glutathione + O2 = glutathione disulfide + H2O2.


sulfur oxygenase/reductase activity

Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+.


prostacyclin receptor activity

Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.


protein insertion into plasma membrane raft

The process in which a protein is incorporated into a plasma membrane raft.


Malpighian tubule development

The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.


FMN reductase (NADPH) activity

Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+.


Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine.


2-hydroxyacyl-CoA lyase activity

Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA.


Notch receptor processing, ligand-independent

The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.


Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate.


positive regulation of lipid localization

Any process that activates or increases the frequency, rate or extent of lipid localization.


atrioventricular node cell fate commitment

The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.


arabinoxylan binding

Binding to arabinoxylan.


cytoplasmic translational elongation

The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.


fermentative hydrogen production

The fermentation of organic substances with a net release of hydrogen.


oocyte microtubule cytoskeleton organization

Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.


Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose.


salicylate 1-monooxygenase activity

Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2.


phthalate 4,5-cis-dihydrodiol dehydrogenase activity

Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD+ = 4,5-dihydroxyphthalate + H+ + NADH.


Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H+.


positive regulation of mannotriose transport

Any process that activates or increases the frequency, rate or extent of mannotriose transport.


homogentisate catabolic process

The chemical reactions and pathways resulting in the breakdown of homogentisate.


Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.


Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP.


lymphoid lineage cell migration

The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.


enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity

Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+.


glycerol to glycerone phosphate metabolic process

The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.


negative regulation of opioid receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway.


quinaldate 4-oxidoreductase activity

Catalysis of the reaction: A + H2O + quinaldate = AH(2) + kynurenate.


protein modification process

The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).


ajugose synthase activity

Catalysis of the reaction: 2 verbascose <=> ajugose + stachyose.


phosphogluco-amylopectin water dikinase activity

Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-amylopectin = n AMP + n hydrogenphosphate + a 6-phosphogluco-3-phosphogluco-amylopectin.


p-coumarate 3-hydroxylase activity

Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+.


anaerobic 2,4,6-trinitrotoluene metabolic process

The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen.


naringenin 2-hydroxylase activity

Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O.


typhasterol C-23 hydroxylase activity

Catalysis of the reaction: typhasterol + O2 + a reduced electron acceptor = castasterone + H2O + an oxidized electron acceptor.


3-ketopimelyl-CoA thiolase activity

Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.


flavonoid 3',5'-hydroxylase activity

Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O.


viral tropism switching

A process by which the range of hosts which a virus can bind and infect is changed. Examples include phages that switch between types of fibers via the action of a virally encoded invertase.


ERBB2-EGFR signaling pathway

The series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.


Catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.


terpentetriene synthase activity

Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene.


funalenone catabolic process

The chemical reactions and pathways resulting in the breakdown of funalenone.


regulation of systemic arterial blood pressure by norepinephrine

The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.


uronic acid transmembrane transporter activity

Enables the transfer of uronic acid from one side of a membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.


oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor.


negative regulation of toll-like receptor 6 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


alpha-ketoglutarate-dependent xanthine dioxygenase activity

Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate.


vitamin D 23-hydroxylase activity

Catalysis of the hydroxylation of C-23 of any form of vitamin D.


homoserine catabolic process

The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid.


negative regulation of R7 cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.


dATP biosynthetic process

The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).


cone photoresponse recovery

The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers.


tryparedoxin peroxidase activity

Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O.


thioether S-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.


fatty acid primary amide metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform primary fatty amides.


superior salivary nucleus development

The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.


germ-line cyst formation

Formation of a group of interconnected cells derived from a single gonial founder cell.


Delta8-sphingolipid desaturase activity

Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor.


establishment of competence for transformation

The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation.


negative phototaxis

The directed movement of a cell or organism away from a source of light.


Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H+ + staurosporine.


positive regulation of SREBP signaling pathway

Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway.


dorsal motor nucleus of vagus nerve structural organization

The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.


emodin biosynthetic process

The chemical reactions and pathways resulting in the formation of emodin.


Catalysis of the reaction: L-arginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H+ + N(omega)-(N-acetyl-beta-D-glucosaminyl)-L-arginyl-[protein] + UDP.


negative regulation of mating type switching

Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.


annealing activity

An activity that facilitates the formation of a complementary double-stranded polynucleotide molecule.


allose kinase activity

Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.


regulation of MyD88-independent toll-like receptor signaling pathway

Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.


positive regulation of convergent extension involved in axis elongation

Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation.


positive regulation of cellular response to amino acid starvation

Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation.


outer medullary collecting duct development

The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.


cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction

The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.


cellular response to carcinoembryonic antigen

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins.


bisphenol A hydroxylase A activity

Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O.


4-aminobutyrate transaminase activity

Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.


negative regulation of starch catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process.


carbon-nitrogen ligase activity on lipid II

Catalysis of the reaction: L-glutamine + lipid II + ATP + H2O = L-glutamate + beta-D-GlcNAc(1->4)-Mur2Ac(oyl-L-Ala-D-isoGln-L-Lys-D-Ala-D-Ala)-diphospho-di-trans,octa-cis-undecaprenol + ADP + phosphate.


The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.


Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H+.


cell dedifferentiation involved in phenotypic switching

A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.


beta-endorphin receptor activity

Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC).


convergent extension involved in metanephric nephron morphogenesis

The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros.


galacturonokinase activity

Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H+.


Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin.


linoleate 9R-lipoxygenase activity

Catalysis of the reaction: linoleate + O2 = 9(R)-HPODE.


adaxial/abaxial axis specification

The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.


homospermidine synthase activity

Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine.


regulation of maternal process involved in parturition

Any process that modulates the frequency, rate or extent of maternal process involved in parturition.


pyoverdine metabolic process

The chemical reactions and pathways involving the siderochrome pyoverdine.


pyranose dehydrogenase (acceptor) activity

Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.


cyclohexylsulfamate metabolic process

The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide.


second mitotic wave involved in compound eye morphogenesis

A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.


cerebellar Purkinje cell precursor proliferation

The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.


angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure

The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.


metanephric early distal convoluted tubule development

The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.


CoA-glutathione reductase (NADP) activity

Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+.


glutamate-methylamine ligase activity

Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H+ + phosphate.


cyclohexanol oxidation

The cyclohexanol metabolic process in which cyclohexanol is converted to adipate.


oospore formation

The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of Oomycetes and certain algae and fungi.


taxadiene synthase activity

Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene.


scopoletin 8-hydroxylase activity

Catalyzes of the reaction: scopoletin + 2-oxoglutarate+O2=fraxetin +succinate+ CO2).


cuticle pigmentation

Establishment of a pattern of pigment in the cuticle of an organism.


RNA guanosine insertion

The modification of an RNA molecule by insertion of a guanosine nucleotide.


benzoate amino acid synthetase activity

Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate.


metanephric cortex development

The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.


galactonolactone dehydrogenase activity

Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.


Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol.


aerobic organosilicon metabolic process

The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen.


intestinal motility

Contractions of the intestinal tract that include peristalsis (moving contents onward) and non-peristaltic movement (moving contents back and forth).


epidermal growth factor signaling pathway involved in forebrain neuron fate commitment

The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.


Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = H+ + S-adenosyl-L-homocysteine + spheroidene.


maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling

Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.


regulation of tRNA export from nucleus

Any process that modulates the frequency, rate or extent of tRNA export from nucleus.


abietadienal hydroxylase activity

Catalysis of the reaction: abietal + NADPH + O2 <=> abietate + NADP + H2O.


carnitine racemase activity

Catalysis of the reaction: D-carnitine = L-carnitine.


Catalysis of the reaction: (5alpha)-campestan-3-one + NADP = H+ + campest-4-en-3-one + NADPH.


DNA-templated transcription open complex formation

Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.


linoleic acid binding

Binding to linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.


flippase activity

Catalysis of the movement of lipids from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.


regulation of ornithine catabolic process

Any process that modulates the frequency, rate or extent of ornithine catabolic process.


Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.


negative regulation of urothelial cell proliferation

Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.


alkylglycerol kinase activity

Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H+.


L-phenylalanine transmembrane transporter activity

Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.


ovary septum development

The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s).


2-furoyl-CoA dehydrogenase activity

Catalysis of the reaction: 2-furoyl-CoA + A + H2O = 5-hydroxy-2-furoyl-CoA + AH(2) + H+.


regulation of timing of subpallium neuron differentiation

The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon.


trichoblast maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state.


chorismate biosynthetic process

The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.


positive regulation of transformation of host cell by virus

Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus.


aerobic phenol-containing compound biosynthetic process

The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.


GDP-L-galactose phosphorylase activity

Catalysis of the reaction: GDP-beta-L-galactose + phosphate = beta-L-galactose-1-phosphate + GDP.


octopamine metabolic process

The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.


Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.


mRNA N-acetyltransferase activity

Catalysis of the reaction: a cytidine in mRNA + acetyl-CoA + ATP + H2O = ADP + an N(4)-acetylcytidine in mRNA + CoA + H+ + phosphate.


cytoskeletal rearrangement involved in phagocytosis, engulfment

The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.


iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide

The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.


regulation of trichoblast fate specification

Any process that modulates trichoblast fate specification.


positive regulation of odontoblast differentiation

Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.


Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.


carotenoid metabolic process

The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.


tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity

Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives.


regulation of molecular function

Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.


intracellular arginine homeostasis

A homeostatic process involved in the maintenance of a steady state level of arginine within a cell.


establishment of cell polarity involved in gastrulation cell migration

The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.


Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O.


limb epidermis development

The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.


selenate adenylyltransferase activity

Catalysis of the reaction: selenic acid + ATP + 2 H+ <=> adenylyl selenate + diphosphoric acid.


3-chlorobenzoate-4,5-oxygenase activity

Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor.


gamma-terpinene synthase activity

Catalysis of the reaction: geranyl diphosphate = gamma-terpinene + diphosphoric acid.


CP2 mannose-ethanolamine phosphotransferase activity

Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.


NAD+- protein-aspartate ADP-ribosyltransferase activity

Catalysis of the reaction: L-aspartyl-[protein] + NAD+ = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide.


regulation of retrograde axon cargo transport

Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.


isoitalicene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene.


clearance of damaged tissue involved in inflammatory response wound healing

The series of events leading to removal of necrotic debris that contribute to an inflammatory response.


syn-copalyl diphosphate synthase activity

Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.


protein localization to microtubule organizing center

A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.


negative regulation of establishment of T cell polarity

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.


2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity

Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP.


actin polymerization-dependent cell migration in host

The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration. The host is defined as the larger of the organisms involved in a symbiotic interaction.


butyryl-CoA dehydrogenase activity

Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein.


mesonephric connecting tubule development

The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.


Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.


glutamine catabolic process to fumarate, using glutamate synthase (NADPH)

The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13).


L-cysteate sulfo-lyase activity

Catalysis of the reaction: L-cysteate + H2O = NH4 + pyruvate + sulfite.


anaerobic phenol-containing compound metabolic process

The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.


lipoprotein localization to membrane

A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.


propanediol dehydratase activity

Catalysis of the reaction: propane-1,2-diol = H2O + propanal.


oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.


Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H.


violaxanthin oxygenase activity

Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.


transforming growth factor beta1 activation

The release of transforming growth factor beta1 (TGF-beta1) from its latent state.


dATP diphosphatase activity

Catalysis of the reaction: dATP + H2O = dAMP + H+ + diphosphate.


arginine 2-monooxygenase activity

Catalysis of the reaction: L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O.


chitin-based larval cuticle pattern formation

The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.


cellular response to vitamin B1

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.


ribonuclease E activity

Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.


arginine decarboxylase activity

Catalysis of the reaction: L-arginine + H+ = agmatine + CO2.


octopamine catabolic process

The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.


GAG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GAG codon.


ABC-type sodium transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na(in) -> ADP + phosphate + Na(out).


protein amidation

Addition of an amide group from a glycine to a protein amino acid.


hercynylcysteine sulfoxide metabolic process

The chemical reactions and pathways involving hercynylcysteine sulfoxide.


somatic diversification of FREP-based immune receptors

The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.


lipo-chitin oligosaccharide transmembrane transporter activity

Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other.


positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation

Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation.


[choline trimethylamine-lyase]-activating enzyme activity

Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).


disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity

Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits.


negative regulation of blood coagulation in another organism

Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.


negative regulation of ovarian follicle development

Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.


convergent extension involved in nephron morphogenesis

The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.


response to fenofibrate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.


catechol 2,3-dioxygenase activity

Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.


nitrobenzene 1,2-dioxygenase activity

Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol.


pilus organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.


The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin.


indole-3-acetic acid amido synthetase activity

Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.


viral release via disruption of host peptidoglycan cell wall

The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.


ureidoglycolate dehydrogenase activity

Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+.


cellular response to abscisic acid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.


response to anion stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.


ascaroside biosynthetic process

The chemical reactions and pathways resulting in the formation of ascaroside.


viral release via pore formation in host cell membrane

The dissemination of mature viral particles from a host cell via the formation by the virus of pores in its host cell membrane.


establishment of protein localization to extracellular region

The directed movement of a protein to a specific location within the extracellular region.


lacto-N-biosidase activity

Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.


interleukin-35 production

The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


iron-cytochrome-c reductase activity

Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+.


6,7-dihydropteridine reductase activity

Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.


Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+.


Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.


myxococcal fruiting body development

The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.


protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.


plant-type cell wall modification involved in stomatal movement

Any plant-type cell wall modification that is involved in stomatal movement.


hydroquinone 1,2-dioxygenase activity

Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde.


The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


inulin fructotransferase (DFA-III-forming) activity

Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


negative regulation of attachment of spindle microtubules to kinetochore

Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.


Catalysis of the reaction: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP+ = a (3R)-2'-hydroxyisoflavanone + H+ + NADPH.


ADP-dependent NAD(P)H-hydrate dehydratase activity

Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H+ + NADH + phosphate.


D-xylose transmembrane transporter activity

Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.


positive regulation of cellotriose metabolic process

Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process.


modification by symbiont of host cell membrane

The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to granulocyte colony-stimulating factor

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.


establishment of thoracic bristle planar orientation

Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.


(1->6)-beta-D-glucan binding

Binding to (1->6)-beta-D-glucan.


2-methylcitrate synthase activity

Catalysis of the reaction: H2O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H+.


positive regulation of monocyte antigen processing and presentation

Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.


positive regulation of synaptic metaplasticity

A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


regulation of cellular process

Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.


positive regulation of hepatocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.


L-cysteine catabolic process to pyruvate

The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate.


Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2.


negative regulation of phospholipase D activity

Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity.


regulation of lymphatic vascular permeability

Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.


carnitinamidase activity

Catalysis of the reaction: (R)-carnitinamide + H2O = (R)-carnitine + NH4.


intracellular borate homeostasis

A homeostatic process involved in the maintenance of a steady state level of tetrahydroxoborate within a cell.


cellular response to papulacandin B

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.


acetaldehyde catabolic process

The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.


Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine.


Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.


ACP-dependent peptidyl-lysine N6-myristoyltransferase activity

Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-[ACP] = H+ + holo-[ACP] + N(6)-tetradecanoyl-L-lysyl-[protein].


saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity

Catalysis of the reaction: L-saccharopine + H2O + NADP+ = L-allysine + L-glutamate + H+ + NADPH.


endosperm development

The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.


galacturonate transmembrane transporter activity

Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate.


jasmonoyl-valine synthetase activity

Catalysis of the reaction: L-valine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine.


Catalysis of the reaction: ATP + UDP-N-acetyl-alpha-D-muramate + L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate.


regulation of astrocyte activation

Any process that modulates the frequency, rate or extent of astrocyte activation.


catalytic activity, acting on a protein

Catalytic activity that acts to modify a protein.


adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway

An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by glucose binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.


delta12-fatty-acid desaturase activity

Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor. This microsomal enzyme introduces a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9.


CoA pyrophosphatase activity

Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine.


isoprenoid diphosphate phosphatase activity

Catalysis of the dephosphorylation of isoprenoid diphosphates.


cell proliferation involved in atrial ventricular junction remodeling

The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.


aromatic amino acid family biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).


myelination of anterior lateral line nerve axons

The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.


trichome papilla formation

The aggregation, arrangement and bonding together of a set of components to form a trichome papilla.


short-day photoperiodism, flowering

A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.


trehalase activity

Catalysis of the hydrolysis of trehalose or a trehalose derivative.


renal system segmentation

The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.


response to stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


low-affinity zinc ion transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


cellular aromatic compound metabolic process

The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.


postsynapse organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse.


negative regulation of L-tyrosine import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell.


pentitol catabolic process

The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.


leaf shaping

The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.


negative regulation of interleukin-35-mediated signaling pathway

Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


drought recovery

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.


negative regulation of intermediate mesodermal cell fate specification

Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.


negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.


retinoic acid receptor signaling pathway involved in somitogenesis

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis.


3-aci-nitropropanoate oxidase activity

Catalysis of the reaction: 3-aci-nitropropanoate + H2O + O2 = 3-oxopropanoate + H2O2 + nitrite.


skeletal muscle satellite cell commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.


maltose O-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose.


Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.


pigment biosynthetic process involved in pigment accumulation

The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.


regulation of tyrosine 3-monooxygenase activity

Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity.


negative regulation of glycine import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell.


o-orsellinic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid.


dextrin transmembrane transporter activity

Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other.


Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.


pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity

Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+.


negative stranded viral RNA transcription

A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.


negative regulation of detection of mechanical stimulus involved in sensory perception of touch

Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.


Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].


protein localization

Any process in which a protein is transported to, or maintained in, a specific location.


red, far-red light phototransduction

The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.


protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine

The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine.


Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate.


dibenzo-p-dioxin catabolic process

The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.


The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-).


positive regulation of ribosomal small subunit export from nucleus

Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus.


nicotinamide riboside metabolic process

The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.


interleukin-15 production

The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


regulation of cardiocyte differentiation

Any process that modulates the frequency, rate or extent of cardiocyte differentiation.


retrograde trans-synaptic signaling by trans-synaptic protein complex

Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.


structural constituent of chitin-based larval cuticle

The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster.


DIBOA-glucoside oxygenase activity

Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide.


sugar mediated signaling pathway

The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.


p-cumate 2,3-dioxygenase activity

Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.


(S)-limonene 1,2-monooxygenase activity

Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide.


methylglutamate dehydrogenase activity

Catalysis of the reaction: N-methyl-L-glutamate + A + H2O = L-glutamate + AH(2) + formaldehyde.


maintenance of seed dormancy by absisic acid

The process by which seed dormancy is maintained by the presence of absisic acid.


vascular associated smooth muscle cell dedifferentiation

The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.


glucan 1,4-beta-glucosidase activity

Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.


abducens nucleus development

The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.


polysome binding

Binding to a polysome.


divinyl chlorophyllide a 8-vinyl-reductase activity

Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+.


Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.


Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.


negative regulation of Schwann cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.


tetrahydrodictyopterin binding

Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.


endoribonuclease activity, cleaving siRNA-paired mRNA

Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.


Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.


aspartoacylase activity

Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.


2,4-dichlorophenoxyacetic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.


subpallium cell migration

The orderly movement of cells from one site to another in the subpallium.


Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine.


positive regulation of starch metabolic process

Any process that activates or increases the frequency, rate or extent of starch metabolic process.


Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.


ovarian follicle endowment

Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.


positive regulation of age-related resistance

Any process that activates or increases the extent of age-related resistance.


Glc3Man9GlcNAc2 oligosaccharide glucosidase activity

Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).


fungal sorus development

The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.


5-methylcytosine biosynthetic process

The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA.


maintenance of dense core granule location

Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.


hydrocarbon metabolic process

The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.


Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.


(-)-isopiperitenone reductase activity

Catalysis of the reaction: (6R)-isoperitenone + H+ + NADPH = (2R,5R)-isopulegone + NADP+.


Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H+.


response to oomycetes

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.


(+)-kotanin metabolic process

The chemical reactions and pathways involving (+)-kotanin.


lupan-3beta,20-diol synthase activity

Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O.


negative regulation of the force of heart contraction

Any process that decreases the force of heart muscle contraction.


D-glycero-D-manno-heptose 7-phosphate metabolic process

The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate.


benzoyl-CoA reductase activity

Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H2O + benzoyl-CoA + reduced ferredoxin.


trimethyllysine dioxygenase activity

Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate.


T cell anergy

Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.


mitotic prometaphase

The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.


glycolytic fermentation to ethanol

The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.


Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol.


pyrimidodiazepine synthase activity

Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.


deep nuclear neuron cell migration

The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.


negative regulation of anthocyanin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process.


ABC-type ferric hydroxamate transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).


response to prostaglandin I

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


Atg12 ligase activity

Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.


proximal/distal pattern formation involved in mesonephric nephron development

The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).


positive regulation of lipid transport across blood-brain barrier

Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.


synaptic membrane adhesion

The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.


box C/D RNA 5'-end processing

Any process involved in forming the mature 5' end of a box C/D RNA molecule.


regulation of granulosa cell proliferation

Any process that modulates the frequency, rate or extent of granulosa cell proliferation.


adhesion of symbiont infection structure to host

The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.


singlet oxygen-mediated programmed cell death

Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.


dimethylamine dehydrogenase activity

Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine.


cyanogenic glycoside biosynthetic process

The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


D-alanine transmembrane transporter activity

Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.


post-embryonic genitalia morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.


protein localization to vacuolar membrane

A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.


The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


regulation of retinal cone cell fate commitment

Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.


Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.


beta-N-acetylgalactosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.


tropomyosin kinase activity

Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin.


trialkylsulfonium hydrolase activity

Catalysis of the hydrolysis of a thioether bond, -S-.


esculetin glucosyltransferase activity

Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+.


regulation of tube diameter

Any process that modulates the diameter of a tube.


arsenate reductase (azurin) activity

Catalysis of the reaction: H2O + arsenite + 2 oxidized azurin = 2 H+ + 2 reduced azurin + arsenate.


cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration

The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H+ + phosphatidyl-N-methylethanolamine.


arabinoxylan-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of an arabinoxylan.


[cytochrome c]-methionine S-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.


Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.


protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine

The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.


envenomation resulting in modulation of complement activation, lectin pathway in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism.


cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity

Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A.


reduced coenzyme F420 oxidase activity

Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O.


UGG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UGG codon.


aspartyl esterase activity

Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.


regulation of preblastoderm mitotic cell cycle

A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle.


ribosylpyrimidine nucleosidase activity

Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.


amino acid catabolic process to carboxylic acid via Ehrlich pathway

The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.


active monoatomic ion transmembrane transporter activity

Enables the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.


phosphocholine hydrolase activity

Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.


entry into host through the stromata

Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.


induction by symbiont of tumor or growth in host

The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.


posterior lateral line nerve glial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.


positive regulation of microglial cell mediated cytotoxicity

Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.


mesonephric juxtaglomerulus cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.


dihydroorotate dehydrogenase (fumarate) activity

Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.


beta-carotene 3-hydroxylase activity

Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O.


dimethyl sulfide monooxygenase activity

Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde.


Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.


histidinol dehydrogenase activity

Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.


ubiquinone biosynthetic process from chorismate

The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.


8-oxo-(d)RTP hydrolase activity

Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+.


CDP catabolic process

The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.


enzyme-linked receptor protein signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription.


2',3'-cyclic GMP-AMP binding

Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.


negative regulation by symbiont of host intracellular transport

Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.


SHREC complex localization

Any process in which a SHREC complex is transported to, or maintained in, a specific location.


negative regulation of neuroinflammatory response

Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.


DNA-templated transcription

The synthesis of an RNA transcript from a DNA template.


protein histidine pros-kinase activity

Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.


Catalysis of the reaction: N-succinyl-L-glutamate + H2O = L-glutamate + succinate.


prephenate(2-) metabolic process

The chemical reactions and pathways involving prephenate(2-).


negative regulation of CD4-positive, alpha-beta T cell costimulation

Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.


positive regulation of platelet formation

Any process that activates or increases the frequency, rate or extent of platelet formation.


regulation of fibroblast chemotaxis

Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.


structural constituent of chromatin

The action of a molecule that contributes to the structural integrity of chromatin.


emericellamide A catabolic process

The chemical reactions and pathways resulting in the breakdown of emericellamide A.


oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.


modulation by virus of host molecular function

The process in which a virus effects a change in the function of a host protein via a direct interaction.


regulation of collecting lymphatic vessel constriction

Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.


epoxyqueuosine reductase activity

Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.


regulation of signaling

Any process that modulates the frequency, rate or extent of a signaling process.


(S)-carnitine 3-dehydrogenase activity

Catalysis of the reaction: (S)-carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.


beta-caryophyllene catabolic process

The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.


argininosuccinate synthase activity

Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.


dermal bone morphogenesis

The process in which bone which forms superficially in the organism are generated and organized.


regulation of interleukin-17-mediated signaling pathway

Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.


response to dehydroepiandrosterone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.


chimeric colonial development

Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.


interleukin-25 receptor activity

Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


chaeta development

The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.


p-coumaroyltriacetic acid lactone synthase activity

Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide.


negative regulation of iron export across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.


Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.


rhombomere 1 formation

The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


regulation of acylglycerol transport

Any process that modulates the frequency, rate or extent of acylglycerol transport.


capsorubin metabolic process

The chemical reactions and pathways involving capsorubin.


hemocyte migration

The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.


aflatoxin reductase (coenzyme F420) activity

Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.


polymeric immunoglobulin binding

Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.


oocyte animal/vegetal axis specification

The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.


candelabrum cell differentiation

The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


regulation of L-tyrosine import across plasma membrane

Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell.


The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.


cyclohexadienyl dehydrogenase activity

Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.


Catalysis of the reaction: L-dopa + O2 + H2O + H+ <=> 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.


positive regulation of mesenchymal cell apoptotic process involved in metanephros development

Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.


antennal joint morphogenesis

The process in which the anatomical structures of the antennal joint are generated and organized.


tetraterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.


Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3.


disruption of host receptor-mediated signal transduction

Any process in which a symbiont interferes with receptor-mediated signal transduction in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.