interleukin-17A receptor activity

Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.


basophil mediated immunity

Any process involved in the carrying out of an immune response by a basophil.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.


Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides.


Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.


fructosamine biosynthetic process

The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


carbon tetrachloride metabolic process

The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.


regulation of Golgi lumen acidification

Any process that modulates the frequency, rate or extent of Golgi lumen acidification.


The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.


formate dehydrogenase (cytochrome) activity

Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.


FAD-dependent histone H3K9me/H3K9me2 demethylase activity

Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.


histidine phosphotransfer kinase activity

Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.


vestibulocochlear nerve structural organization

The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


hyaloid vascular plexus regression

The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.


paternal behavior

Male behaviors associated with the care and rearing offspring.


catalytic activity, acting on DNA

Catalytic activity that acts to modify DNA.


dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.


siroheme metabolic process

The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.


positive regulation of mesenchymal stem cell migration

Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration.


urotensin II receptor activity

Combining with urotensin II to initiate a change in cell activity.


Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains.


The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.


paclitaxel biosynthetic process

The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.


manchette assembly

The aggregation, arrangement and bonding together of a set of components to form a manchette.


convergent extension involved in rhombomere morphogenesis

Any convergent extension that is involved in rhombomere morphogenesis.


epinephrine-mediated vasodilation

A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings.


peptidyl-histidine methylation, to form pros-methylhistidine

The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).


organ boundary specification between lateral organs and the meristem

The process in which boundaries between lateral organs and the meristem is established and maintained.


Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.


G-quadruplex DNA formation

A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.


mesenchymal cell proliferation involved in ureter development

The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.


amorpha-4,11-diene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.


TNFSF11 receptor activity

Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function.


lateral pseudopodium retraction

The myosin-based contraction and retraction of a lateral pseudopodium.


Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H+.


Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.


clearance of cells from fusion plate by epithelial to mesenchymal transition

The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.


caffeate O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.


7,8-dihydromonapterin aldolase activity

Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol.


mitochondrial unfolded protein response

The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.


response to perphenazine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.


ligamentous ossification

Ossification wherein bone tissue forms within ligamentous tissue.


negative regulation of behavioral fear response

Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response.


dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.


CUG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CUG codon.


regulation of R7 cell differentiation

Any process that modulates the frequency, rate or extent of R7 differentiation.


casbene synthase activity

Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.


anaerobic pectin catabolic process

The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen.


dihydroneopterin triphosphate 2'-epimerase activity

Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate.


benzil reductase [(S)-benzoin-forming] activity

Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+.


(+)-kotanin biosynthetic process

The chemical reactions and pathways resulting in the formation of (+)-kotanin.


protein localization to ciliary transition zone

A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.


aerobactin synthase activity

Catalysis of the reaction: ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine = aerobactin + AMP + diphosphate + H+.


beta-pinacene synthase activity

Catalysis of the cyclization of geranylgeranyl pyrophosphate (GGPP) to yield the monocyclic diterpene beta-pinacene.


benzoate metabolic process

The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.


Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H+.


P-methyltransferase activity

Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule.


methylamine dehydrogenase (amicyanin) activity

Catalysis of the reaction: 2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H+ + NH4+ + 2 reduced [amicyanin].


positive regulation of interleukin-27-mediated signaling pathway

Any process that increases the rate, frequency or extent of an interleukin-27-mediated signaling pathway.


funalenone metabolic process

The chemical reactions and pathways involving funalenone.


L-arabinitol 2-dehydrogenase activity

Catalysis of the reaction: L-arabinitol + NAD+ = L-ribulose + H+ + NADH.


Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+.


Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.


ATP-dependent chromatin remodeler activity

An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.


negative regulation of monocyte antigen processing and presentation

Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.


proteolysis within lysosome associated with antigen processing and presentation

The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.


termination of G protein-coupled receptor signaling pathway

The signaling process in which G protein-coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal.


thymic stromal lymphopoietin production

The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


cellular response to interleukin-21

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.


amino acid:potassium symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).


negative regulation of endosperm development

Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development.


dimethylglycine dehydrogenase activity

Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.


border follicle cell migration

The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.


aerial mycelium formation

The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae.


U11 snRNA binding

Binding to a U11 small nuclear RNA (U11 snRNA).


cystathionine beta-lyase activity

Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.


endothelin receptor signaling pathway involved in heart process

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.


1,2,3-tribromopropane metabolic process

The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.


malonyl-CoA methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + a malonyl-[acp] = S-adenosyl-L-homocysteine + a malonyl-[acp] methyl ester.


mannuronate reductase activity

Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+.


peptidoglycan endopeptidase activity

An endopeptidase activity that uses peptidoglycan as a substrate.


regulation of late stripe melanocyte differentiation

Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.


protein catabolic process at postsynapse

The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse.


imaginal disc-derived wing morphogenesis

The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.


suramin binding

Binding to suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms.


mesonephric nephron tubule development

The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


ABC-type D-methionine transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).


glycolytic process from fructose through fructose-6-phosphate

The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.


negative regulation of amniotic stem cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation.


positive phototaxis

The directed movement of a cell or organism towards a source of light.


pyrimidine deoxyribonucleoside binding

Binding to a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.


oxaloacetate tautomerase activity

Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.


tetracyclic triterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.


Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-).


cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane

The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport.


epidermal growth factor catabolic process

The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.


iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide

The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide.


heparin-sulfate lyase activity

Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.


alginic acid acetylation

The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate.


Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-.


ABC-type protein transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).


positive regulation of small molecule metabolic process

Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process.


The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-).


mannitol dehydrogenase activity

Catalysis of the reaction: D-mannitol + NAD+ = D-mannose + H+ + NADH.


acetylglutamate kinase activity

Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate.


translation at synapse

Translation that occurs at the synapse.


rhamnogalacturonan II side chain metabolic process

The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively.


U6atac snRNA binding

Binding to a U6atac small nuclear RNA (U6atac snRNA).


5-aminopentanamidase activity

Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3.


regulation of colon smooth muscle contraction

Any process that modulates the frequency, rate or extent of colon smooth muscle contraction.


Lewis a epitope biosynthetic process

The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.


menthol biosynthetic process

The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.


Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H+ = a 5-beta-3-oxo-steroid + NADP+.


Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid.


disruption of host antimicrobial peptide activity

Any process in which a symbiont interferes with a host antimicrobial peptide, for example by cleavage or degredation.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) + Cl-(out) = norepinephrine(in) + Na+(in) + Cl-(in).


IgD binding

Binding to an immunoglobulin of a D isotype.


L-diaminopimelate transmembrane transporter activity

Enables the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.


osmoregulated periplasmic glucan metabolic process

The chemical reactions and pathways involving osmoregulated periplasmic glucan.


Catalysis of the reaction: glycyrrhizate + H2O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate.


detection of high humidity stimulus involved in sensory perception

The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity.


L-threonine catabolic process to D-lactate

The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate.


carbapenem metabolic process

The chemical reactions and pathways involving carbapenem.


phytosteroid biosynthetic process

The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.


cell projection organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.


fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.


positive regulation of cilium beat frequency involved in ciliary motility

Any process that activates or increases the frequency of cilium beating involved in ciliary motility.


regulation of eosinophil extravasation

Any process that modulates the frequency, rate or extent of eosinophil extravasation.


axial mesoderm structural organization

The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.


glyoxylate reductase (NAD+) activity

Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH.


ureter part of ureteric bud development

The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.


rhombomere 1 development

The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


detection of auxin stimulus

The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal.


positive regulation of R7 cell differentiation

Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.


Catalysis of the reaction: S-adenosyl-L-methionine + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+.


gamma-delta T cell activation involved in immune response

The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.


L-xylitol metabolic process

The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.


D-cysteine metabolic process

The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.


Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O.


negative regulation of oligopeptide transport

Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport.


vesicle fusion with endoplasmic reticulum

The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.


Catalysis of the reaction: UDP-glucose + tomatidine = UDP + O-glucosyl-tomatidine.


negative regulation of platelet rolling

Any process that decreases the rate, frequency, or extent of platelet rolling.


tracheal outgrowth, open tracheal system

The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster.


acetanilide 1,2-dioxygenase activity

Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide.


1-acyl dihydroxyacetone phosphate reductase activity

Catalysis of the reaction: 1-oleoylglycerone 3-phosphate + NADPH + H+ = 1-oleoyl-sn-glycero-3-phosphate + NADP.


regulation of compound eye retinal cell programmed cell death

Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.


negative regulation of glucosylceramidase activity

Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity.


SOS response

An error-prone process for repairing damaged microbial DNA.


establishment of natural killer cell polarity

The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.


anaerobic gallate catabolic process

The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen.


levansucrase activity

Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1).


11-deoxycorticosterone binding

Binding to 11-deoxycorticosterone.


3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity

Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].


glycerol ether catabolic process

The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.


chorion-containing eggshell formation

The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.


Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.


ethanolamine ammonia-lyase activity

Catalysis of the reaction: ethanolamine = acetaldehyde + NH3.


alpha-glucuronidase activity

Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate.


response to etoposide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.


detection of hypoxic conditions in blood by aortic body chemoreceptor signaling

The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.


capsanthin metabolic process

The chemical reactions and pathways involving capsanthin.


regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction

Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.


The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine.


cyclohexanone dehydrogenase activity

Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone.


Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+.


5-aminosalicylate dioxygenase activity

Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate.


reduced coenzyme F420:NADP+ oxidoreductase activity

Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.


sinapate ester metabolic process

The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


spermidine:sinapoyl CoA N-acyltransferase activity

Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule.


CUA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CUA codon.


telophase

The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.


L-rhamnose mutarotase activity

Catalysis of the reaction: alpha-L-rhamnose = beta-L-rhamnose.


The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


response to interleukin-21

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.


long-chain acyl-CoA hydrolase activity

Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length.


cellular response to silver ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.


Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).


cellular response to rapamycin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.


2-hydroxybenzoyl-CoA catabolic process

The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA.


lipoarabinomannan binding

Binding to lipoarabinomannan.


xanthosine nucleotidase activity

Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.


psilocybin biosynthetic process

The chemical reactions and pathways resulting in the formation of psilocybin, a psychotropic tryptamine-derived natural product.


regulation of compound eye photoreceptor cell differentiation

Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation.


smooth muscle hypertrophy

The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.


Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.


positive regulation of CAMKK-AMPK signaling cascade

Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade.


tetracycline transmembrane transporter activity

Enables the transfer of tetracycline from one side of a membrane to the other. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).


microglial cell mediated cytotoxicity

The directed killing of a target cell by a microglial cell.


histone H4K12 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12).


argininosuccinate lyase activity

Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.


pyruvate dehydrogenase (quinone) activity

Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.


aminoacyl-tRNA metabolism involved in translational fidelity

Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.


positive regulation of zygospore formation

Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.


sinoatrial valve development

The progression of the sinoatrial valve over time, from its formation to the mature structure.


creatininase activity

Catalysis of the reaction: creatinine + H2O = creatine.


non-myelinated axon ensheathment

The process in which a non-myelinating glial cell membrane closes around an axon.


gibberellin A25 hydroxylase activity

Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide.


ecdysone metabolic process

The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development.


positive regulation of cytosolic calcium ion concentration involved in egg activation

The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.


CAM photosynthesis

The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis.


zeaxanthin catabolic process

The chemical reactions and pathways resulting in the breakdown of zeaxanthin.


Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP.


ATPase-coupled antimonite transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out).


suppression by virus of host natural killer cell activation

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host.


posterior compartment specification

The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.


clathrin-mediated membrane bending

A membrane bending process mediated by clathrin.


Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.


hydroxymethylfurfural reductase (NADH) activity

Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.


regulation of defecation rhythm

Any process that modulates the frequency, rate or extent of defecation rhythm.


protein localization to phagocytic vesicle

A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle.


positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway

Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


haustorium mother cell formation

The process in which a symbiont cell is formed, separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


non-phosphorylated glucose metabolic process

The chemical reactions and pathways involving non-phosphorylated forms of glucose.


nitrobenzene nitroreductase activity

Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O.


inositol 3-kinase activity

Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.


thienylcyclohexylpiperidine binding

Binding to thienylcyclohexylpiperidine.


negative regulation of distal tip cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration.


24-epi-campsterol desaturase activity

Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O.


Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O.


beta-carotene isomerase activity

Catalyzes the reaction: all-trans-beta-carotene = 9-cis-beta-carotene.


Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.


penetration peg formation

The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.


heparan sulfate 2-O-sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.


trypanothione-disulfide reductase (NADP) activity

Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.


maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded

Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster.


gamma-linolenate elongase activity

Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide.


negative regulation of compound eye retinal cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.


(+)-kotanin catabolic process

The chemical reactions and pathways resulting in the breakdown of (+)-kotanin.


FAD transmembrane transporter activity

Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.


alcohol O-cinnamoyltransferase activity

Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate.


voltage-gated sodium channel activity involved in AV node cell action potential

Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


wall teichoic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


trisporic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of trisporic acid.


abscisic aldehyde oxidase activity

Catalysis of the reaction: (+)-abscisic aldehyde + H2O + O2 = abscisate + H2O2 + H+.


nicotinic acid receptor activity

Combining with nicotinic acid to initiate a change in cell activity.


choline O-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.


kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP.


GA5 2,3 epoxidase activity

Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide.


sepiapterin deaminase activity

Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3.


2-methylisocitrate dehydratase activity

Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H2O.


positive regulation of wax biosynthetic process

Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.


Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.


detection of brassinosteroid stimulus

The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal.


positive regulation of neutrophil mediated cytotoxicity

Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


naphthalene catabolic process

The chemical reactions and pathways resulting in the breakdown of naphthalene.


dimethylsilanediol hydroxylase activity

Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.


renal potassium excretion

The elimination of potassium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.


3'-tRNA processing endoribonuclease activity

Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.


C-terminal protein demethylation

The removal of a methyl group from the C-terminal amino acid of a protein.


homoglutathione synthase activity

Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H+ + phosphate.


thalianol metabolic process

The chemical reactions and pathways involving the triterpene thalianol.


exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.


catalytic activity, acting on a glycoprotein

Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein.


L-glycol dehydrogenase activity

Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.


Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine.


snRNA localization to Cajal body

The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body.


L-arabinose catabolic process to xylulose 5-phosphate

The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate.


mitochondrial tRNA wobble position uridine thiolation

The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.


jasmonyl-Ile conjugate hydrolase activity

Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.


coniferin beta-glucosidase activity

Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.


L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)

Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O.


dorsal closure, amnioserosa morphology change

The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.


negative regulation of anther dehiscence

Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence.


pollen tube guidance

The process in which the growth of pollen tube is directed towards the female gametophyte.


modulation by symbiont of host T-cell mediated immune response

Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate.


rRNA (cytosine) methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.


collagen and cuticulin-based cuticle attachment to epithelium

Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.


negative regulation of entry of bacterium into host cell

Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.


medial fin morphogenesis

The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


vitelline membrane formation involved in chorion-containing eggshell formation

Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.


lutein oxygenase activity

Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.


Gram-negative-bacterium-type cell outer membrane assembly

The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.


phenolic phthiocerol biosynthetic process

The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.


invagination involved in gastrulation with mouth forming second

The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation.


establishment of secretory granule localization

The directed movement of a secretory granule to a specific location.


disruption of host cAMP-mediated signal transduction

Any process in which the symbiont organism interferes with cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of iridophore differentiation

Any process that modulates the frequency, rate or extent of iridophore differentiation.


regulation of intracellular signal transduction

Any process that modulates the frequency, rate or extent of intracellular signal transduction.


spermine transmembrane transporter activity

Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.


CGU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CGU codon.


L-isoleucine biosynthetic process

The chemical reactions and pathways resulting in the formation of L-isoleucine.


hydroxy-nicotine oxidase activity

Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.


MHC class I protein complex assembly

The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.


negative regulation of pro-T cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.


epithelial cell fate determination, open tracheal system

The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster.


intermediate mesodermal cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.


regulation of cyanophore differentiation

Any process that modulates the frequency, rate or extent of cyanophore differentiation.


Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.


negative regulation of egg-laying behavior

Any process that stops, prevents or reduces the frequency, rate or extent of oviposition.


anterior compartment pattern formation

The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.


ATPase-coupled phosphate ion transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).


creatinine catabolic process

The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.


negative regulation of vascular associated smooth muscle cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.


replacement bone morphogenesis

The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.


S phase

The cell cycle phase, following G1, during which DNA synthesis takes place.


post-embryonic hindgut morphogenesis

The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.


The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.


negative regulation of chromosome separation

Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.


peptidyl-threonine palmitoylation

The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.


cell wall (1->3)-beta-D-glucan metabolic process

The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


negative regulation of response to salt stress

Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.


Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.


Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H+ + UDP.


nucleotide-sulfate transmembrane transporter activity

Enables the transfer of nucleotide-sulfate from one side of a membrane to the other.


kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP.


regulation of ureter smooth muscle cell differentiation

Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.


Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.


detoxification of free heme

Any process that reduces or removes the toxicity of free heme. These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme.


spermine oxidase (propane-1,3-diamine-forming) activity

Catalysis of the reaction: H2O + O2 + spermine = 1,3-diaminopropane + H2O2 + N-(3-aminopropyl)-4-aminobutanal.


fimbrial usher porin activity

A porin that acts in the assembly of fimbria together with fimbrial chaperone.


palmitoyl-CoA ligase activity

Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.


isopenicillin-N synthase activity

Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 = 2 H2O + isopenicillin N.


cellular response to carbon dioxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.


lysyl-tRNA aminoacylation

The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA.


phenylethylamine biosynthetic process

The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.


Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H+ + UDP.


manganese peroxidase activity

Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O.


positive regulation of development, heterochronic

Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached.


flight behavior

The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.


response to farnesol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.


Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O.


innate vocalization behavior

A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.


2-enoate reductase activity

Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.


negative regulation of hemocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.


ferredoxin-NAD(P) reductase activity

Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.


Catalysis of the reaction: L-glutamyl-[protein] + NAD+ = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide.


negative regulation of shoot apical meristem development

Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development.


toluene-containing compound metabolic process

The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.


positive regulation of mesodermal cell differentiation

Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.


Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.


ecdysone oxidase activity

Catalysis of the reaction: Ecdysone + O2 = 3-dehydroecdysone + H2O2.


sucrose transmembrane transporter activity

Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.


cellular response to GW 7647

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.


stachyose galactinol:verbascose galactosyltransferase activity

Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol.


regulation of G-protein activated inward rectifier potassium channel activity

Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.


cellular response to gastrin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.


Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).


arsenate reductase activity

Catalysis of the interconversion of arsenate and arsenite.


tryptophan catabolic process to catechol

The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol.


methylselenol reductase activity

Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O.


dorsal cochlear nucleus development

The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.


alpha-pinene monooxygenase [NADH] activity

Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.


leg disc proximal/distal pattern formation

The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.


visceral mesoderm-endoderm interaction involved in midgut development

The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.


proteolysis within endosome associated with antigen processing and presentation

The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.


intracellular sulfate ion homeostasis

A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell.


N-carbamoylputrescine amidase activity

Catalysis of the reaction: N-carbamoylputrescine + H2O + 2 H+ = CO2 + NH4 + putrescine.


photosynthetic electron transport chain

A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.


Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.


cellular response to histidine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.


positive regulation of leukotriene production involved in inflammatory response

Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


envenomation resulting in hemorrhagic damage in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.


Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.


arsenate reductase (donor) activity

Catalysis of the reaction: A + arsenite + H2O = AH(2) + arsenate + 2 H+.


xanthophyll biosynthetic process

The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.


Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate.


aerobic respiration, using ammonia as electron donor

The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.


phenylalanine ammonia-lyase activity

Catalysis of the reaction: L-phenylalanine = NH4 + trans-cinnamate.


sesquiterpene metabolic process

The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.


complement component C3d receptor activity

Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


muscle thin filament assembly

The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.


cellular response to fluoride

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.


Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.


negative regulation of basidiospore formation

Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.


Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP.


B cell chemotaxis across high endothelial venule

The movement of a B cell to cross a high endothelial venule in response to an external stimulus.


Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H+ + luciferyl sulfate.


chloroplast RNA processing

The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.


ecdysteroid 22-hydroxylase activity

Catalysis of the hydroxylation of an ecdysteroid at carbon position 22.


glutamic-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.


negative regulation of thymine transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus

Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.


hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.


glutamine catabolic process to fumarate

The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate.


lipoic acid binding

Binding to lipoic acid, 1,2-dithiolane-3-pentanoic acid.


lycopene metabolic process

The chemical reactions and pathways involving lycopene.


Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.


gramicidin S catabolic process

The chemical reactions and pathways resulting in the breakdown of gramicidin S.


3-oxoadipyl-CoA thiolase activity

Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.


apiogalacturonan metabolic process

The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.


Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.


monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity

Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.


regulation of FtsZ-dependent cytokinesis

Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis.


Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H+.


lateral mesodermal cell fate commitment

The process in which a cell becomes committed to become a lateral mesoderm cell.


Catalysis of the reaction: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O.


Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.


poly(beta-D-mannuronate) lyase activity

Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.


Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).


positive regulation of exit from meiosis

Any process that activates or increases the frequency, rate or extent of exit from meiosis.


structural constituent of cutaneous appendage

The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.


aerobic phenol-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.


specification of metanephric proximal tubule identity

The process in which the proximal tubule of the metanephric nephron acquires its identity.


S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity

Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine.


abscisic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.


circadian sleep/wake cycle, wakefulness

The part of the circadian sleep/wake cycle where the organism is not asleep.


protein localization to prospore membrane

A process in which a protein is transported to, or maintained in, a location within a prospore membrane.


limb spinous cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


beta-N-acetylglucosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.


regulation of pharynx morphogenesis

Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.


basal dendrite morphogenesis

The process in which the anatomical structures of a basal dendrite are generated and organized.


cellular response to selenium ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.


contact chemoreceptor activity

A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.


Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.


regulation of cell adhesion involved in sprouting angiogenesis

Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.


regulation of imaginal disc-derived leg joint morphogenesis

Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.


intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential

Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential.


response to polyamine macromolecule

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.


Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.


CENP-A containing nucleosome binding

Binding to a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).


cellular response to serotonin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.


negative regulation of cellular response to heat

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat.


Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+.


citrate-L-glutamate ligase activity

Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.


transmembrane histidine kinase cytokinin receptor activity

Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.


maintenance of protein location in cell cortex of cell tip

A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.


regulation of backward locomotion

Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.


myo-inositol transmembrane transporter activity

Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.


molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide

The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide.


bacteriochlorophyll metabolic process

The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.


(R)-2-methylmalate dehydratase activity

Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H2O.


arogenate dehydrogenase (NADP+) activity

Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.


Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP + H+ = diphosphate + GDP-beta-L-fucose.


picolinic acid metabolic process

The chemical reactions and pathways involving picolinic acid.


negative regulation of secondary cell wall biogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.


polyphosphate-mediated signaling

Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.


alcohol dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.


glycerol dehydrogenase [NADP+] activity

Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.


proboscis morphogenesis

The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.


negative regulation of lateral motor column neuron migration

Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration.


4-toluenecarboxylate metabolic process

The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.


xylulokinase activity

Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H+.


positive regulation by symbiont of ethylene levels in host

Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.


T cell tolerance induction to tumor cell

A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.


cyanidin 3,7-diglucoside glucosidase activity

Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.


subpallium glioblast cell division

The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes.


reproductive fruiting body development

The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.


glutamate catabolic process to oxaloacetate

The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate.


mannose-1-phosphate guanylyltransferase (GTP) activity

Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose.


cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.


CDP-diacylglycerol catabolic process

The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.


acyl-CoA binding

Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.


Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine.


transitional two stage B cell differentiation

The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.


cell wall polysaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides.


Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.


RNA trimethylguanosine synthase activity

Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.


aldehyde dehydrogenase (FAD-independent) activity

Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor.


teliospore formation

The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.


establishment of pole plasm mRNA localization

Any process that results in the directed movement of mRNA to the oocyte pole plasm.


leukotriene D4 catabolic process

The chemical reactions and pathways resulting in the breakdown of leukotriene D4.


negative regulation of cell chemotaxis to fibroblast growth factor

Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.


adult chitin-based cuticle development

Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster.


Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.


positive regulation of Schwann cell chemotaxis

Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.


cell motility in response to calcium ion

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.


malyl-CoA lyase activity

Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.


light-activated voltage-gated calcium channel activity

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


regulation of microglia differentiation

Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.


carbohydrate derivative binding

Binding to a carbohydrate derivative.


interferon-tau production

The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


early neuron fate commitment in forebrain

The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.


D-amino acid transmembrane transporter activity

Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.


active borate transmembrane transporter activity

Enables the transport of borate across a membrane against the concentration gradient.


ERBB3 signaling pathway

The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission.


photosystem II repair

Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.


Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+.


positive regulation of pyloric antrum smooth muscle contraction

Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


pyrrolysyl-tRNA synthetase activity

Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl).


nucleus-vacuole junction assembly

The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction (NVJ), membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. The NVJ plays roles in piecemeal microautophagy of the nucleus and in the cytoplasm-to-vacuole targeting pathway.


17-beta-ketosteroid reductase activity

Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.


cell wall chitin biosynthetic process

The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.


protein malonylation

The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.


positive regulation of plasmatocyte differentiation

Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.


vacuolar calcium ion homeostasis

Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.


GTP diphosphatase activity

Catalysis of the reaction: GTP + H2O = GMP + H+ + diphosphate.


imaginal disc-derived genitalia development

The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.


cardioblast cell fate determination

The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


dehydrogluconate dehydrogenase activity

Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).


host interaction involved in quorum sensing

A quorum sensing process that is modulated by some interaction with a host cell or organism.


Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.


positive regulation of defecation rhythm

Any process that activates or increases the frequency, rate or extent of defecation rhythm.


averantin hydroxylase activity

Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O2 <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H2O. Involved in aflatoxin biosynthesis.


purine deoxyribonucleoside biosynthetic process

The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


regulation of osmosensory signaling pathway

Any process that modulates the frequency, rate or extent of osmosensory signaling pathway.


anterior semicircular canal development

The progession of the anterior semicircular canal from its initial formation to the mature structure.


endocytosis, site selection

The process of selecting and or marking the position where endocytosis will occur.


mycothiol-dependent formaldehyde dehydrogenase activity

Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.


positive regulation of iodide transport

Any process that activates or increases the frequency, rate or extent of iodide transport.


regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


B cell anergy

Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.


axon regeneration at neuromuscular junction

The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.


regulation of short-term synaptic potentiation

Any process that modulates the frequency, rate or extent of short-term synaptic potentiation.


positive regulation of bile acid secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.


low-density lipoprotein particle receptor catabolic process

The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.


genital disc pattern formation

The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.


ornithine cyclodeaminase activity

Catalysis of the reaction: L-ornithine = L-proline + NH4.


positive regulation of stomach fundus smooth muscle contraction

Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.


Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8.


dopaminergic neuron axon guidance

The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.


anaerobic nitrilotriacetate metabolic process

The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen.


mating-type alpha-factor pheromone receptor activity

Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity.


ketohexokinase activity

Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.


thiamine pyrophosphate transmembrane transporter activity

Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.


negative regulation of cellular defense response

Any process that stops, prevents, or reduces the rate of the cellular defense response.


pronephric duct development

The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.


estrogen 2-hydroxylase activity

Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O.


anandamide epoxidase activity

Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide.


protein localization to microtubule end

A process in which a protein is transported to, or maintained in, a location at a microtubule end.


N-terminal protein formylation

The formylation of the N-terminal amino acid of proteins.


regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation

Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.


gibberellin transmembrane transporter activity

Enables the transfer of gibberellin from one side of a membrane to the other.


The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.


D-threonine aldolase activity

Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.


capsule poly-gamma-glutamate biosynthetic process

The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.


D-cysteine desulfhydrase activity

Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate.


negative regulation of gamma-delta T cell activation

Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation.


dorsal motor nucleus of vagus nerve development

The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.


C-C motif chemokine 21 receptor activity

Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


phosphoadenylylsulfatase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate.


cis-acting DNA replication termination

A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.


cellobiose dehydrogenase (acceptor) activity

Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.


lutein metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.


positive regulation of retrograde axon cargo transport

Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.


Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity

Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.


Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP + 2 H+.


Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.


Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.


behavioral defense response to insect

A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.


snoRNA splicing

The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.


conversion of lysyl-tRNA to pyrrolysyl-tRNA

The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).


O-succinylbenzoate synthase activity

Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.


protein-heme linkage via 1'-L-histidine

The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine).


deoxyinosine metabolic process

The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside.


pantothenate transmembrane transporter activity

Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.


beta-primeverosidase activity

Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.


R7 cell development

The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.


natural killer cell differentiation involved in immune response

The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.


selenium-containing prosthetic group biosynthetic process

The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.


transmitting tissue development

The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.


cellular detoxification of fluoride

Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include chemical modification or transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


N-terminal protein amino acid carboxylation

The carboxylation of the N-terminal amino acid of proteins.


Wnt signaling pathway involved in animal/vegetal axis specification

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.


GDP-mannose 6-dehydrogenase activity

Catalysis of the reaction: GDP-alpha-D-mannose + H2O + 2 NAD+ = GDP-D-mannuronate + 3 H+ + 2 NADH.