Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.


tRNA nucleotidyltransferase activity

Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.


phosphatidylserine catabolic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.


crotonyl-CoA hydratase activity

Catalysis of the reaction: Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.


Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O.


regulation of plasma membrane sterol distribution

Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane.


DNA synthesis involved in DNA replication

Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.


3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity

Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.


Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate.


pole plasm mitochondrial srRNA localization

Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


central nervous system interneuron axonogenesis

Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.


monoatomic anion:sodium symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic anion(out) + Na+(out) = monoatomic anion(in) + Na+(in).


epithelial to mesenchymal transition involved in cardiac fibroblast development

A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.


all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity

Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate.


intracellular phosphatidylinositol-3,5-bisphosphate-sensitive monatomic cation channel activity

Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.


peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine

The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link.


8-oxo-GDP phosphatase activity

Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.


endothelial cell-matrix adhesion

The binding of an endothelial cell to the extracellular matrix via adhesion molecules.


negative regulation of cardiac conduction

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.


Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.


floral whorl formation

The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.


The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.


The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


protein localization to cortical endoplasmic reticulum

A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.


glycine dehydrogenase activity

Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH.


positive regulation of metula development

Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


negative regulation of invasive growth in response to glucose limitation

Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation.


ITPase activity

Catalysis of the reaction: ITP + H2O = IDP + H+ + phosphate.


renal phosphate ion absorption

A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.


Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-alanyl-tRNA(Ala) = 1,2-diacyl-sn-glycero-3-phospho-1'-(3'-O-L-alanyl)-sn-glycerol + tRNA(Ala).


photosynthetic electron transport in photosystem I

A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP.


galactomannan biosynthetic process

The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.


regulation of innate immunity memory response

Any process that modulates the frequency, rate or extent of innate immunity memory response.


mesenchymal cell fate commitment

The process in which a cell becomes committed to become a mesenchymal cell.


cysteine-type aminopeptidase activity

Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


histone deubiquitinase activity

A deubiquitinase that cleaves ubiquitin from a histone protein to which it is conjugated.


emericellin catabolic process

The chemical reactions and pathways resulting in the breakdown of emericellin.


The process of immune complex clearance by erythrocytes. The process often starts with binding of complement receptor 1 (CR1) on the surface of erythrocytes to a complement coated immune complex. The complex bound to erythrocyte CR1 is then transported to the liver or spleen where it is presented to phagocytes. The process ends when the complex is removed from CR1, allowing the erythrocyte to return to general circulation.


3-chlorobenzoate-3,4-oxygenase activity

Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor.


high-affinity glutamine transmembrane transporter activity

Enables the transfer of glutamine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


anther wall tapetum cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.


glucose catabolic process to lactate via pyruvate

The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).


Catalysis of the reaction: GDP-alpha-D-mannose + queuosine34 in tRNA(Asp) = GDP + H+ + O-4''-alpha-D-mannosylqueuosine34 in tRNA(Asp).


homophytochelatin synthase activity (polymer-forming)

Catalysis of the reaction: glutathionate + a poly gamma-glutamylcysteine-beta-alanine = glycine + a poly gamma-glutamylcysteine-beta-alanine.


ABC-type bile acid transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.


cellular response to nitrogen dioxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.


leaf formation

The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.


Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH4 + oxaloacetate.


chlorite O2-lyase activity

Catalysis of the reaction: chloride + O2 = chlorite.


formylaspartate deformylase activity

Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.


mesonephric glomerular mesangial cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.


Catalysis of the reaction: L-tyrosyl-[protein] + NAD+ = H+ + nicotinamide + O-(ADP-D-ribosyl)-L-tyrosyl-[protein].


maintenance of viral latency

The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.


modulation by symbiont of defense-related host calcium ion flux

Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cellular modified histidine catabolic process

The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


oogonium stage

The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.


Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.


negative regulation of extraocular skeletal muscle development

Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.


benzonitrile metabolic process

The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin.


beta-zeacarotene catabolic process

The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene.


P-type zinc transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out).


phenylethylamine metabolic process

The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.


ADP-ribosyl cyclase activity

Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide.


positive regulation of sterol import

Any process that activates or increases the frequency, rate or extent of sterol import.


anterior midgut invagination

Internalization of the anterior midgut into the interior of the embryo.


response to Gram-positive bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a Gram-positive bacterium.


Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA.


aromatic amino acid family catabolic process to alcohol via Ehrlich pathway

The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.


pronephric nephron morphogenesis

The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.


tRNA adenosine deamination to inosine

The removal of an amine group from an adenosine to produce inosine within a tRNA molecule.


glycogen cell differentiation involved in embryonic placenta development

The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.


regulation of gamma-delta T cell activation involved in immune response

Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response.


tyramine N-feruloyltransferase activity

Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.


succinyl-CoA pathway

The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.


negative regulation of calcium channel activity in another organism

Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism.


thyrotropin-releasing hormone receptor activity

Combining with thyrotropin-releasing hormone to initiate a change in cell activity.


ground meristem histogenesis

The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.


lagging strand initiation

The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.


Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate.


sphingosine hydroxylase activity

Catalysis of the hydroxylation of sphingolipid long chain bases.


regulation of aorta morphogenesis

Any process that modulates the frequency, rate or extent of aorta morphogenesis.


Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.


molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide

The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.


amidinoaspartase activity

Catalysis of the reaction: N-amidino-L-aspartate + H2O = L-aspartate + urea.


gamma-delta T cell proliferation

The expansion of a gamma-delta T cell population by cell division.


pheromone biosynthetic process

The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.


glyoxylate reductase activity

Catalysis of the reaction: glycolate + NAD(P)+ = glyoxylate + NAD(P)H.


Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.


canonical Wnt signaling pathway involved in mesonephric nephron development

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


ATP-dependent protein folding chaperone

Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.


thiosulfate dehydrogenase activity

Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.


The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.


glutathione-dependent sulfide quinone oxidoreductase activity

Catalysis of the reaction: a quinone + glutathione + H(+) + hydrogen sulfide <=> a quinol + S-sulfanylglutathione.


coronary sinus valve development

The progression of the valve of the coronary sinus over time, from its formation to the mature structure.


negative regulation of locomotor rhythm

Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm.


complement component C1q receptor activity

Combining with the C1q complex, a component of the classical complement cascade, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


positive regulation of signaling

Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.


central nervous system structural organization

The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


peptidyl-1-thioglycine biosynthetic process, internal

The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.


establishment of left sidedness

The initial formation of the type asymmetry in an organism's body plan or part of an organism that established the pattern characteristic to its left side.


oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.


efferent axon development in posterior lateral line nerve

The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.


histone H4S1 kinase activity

Catalysis of the reaction: histone H4-serine (position 1) + ATP = histone H4-phosphoserine (position 1) + ADP. This reaction is the addition of a phosphate group to the serine residue at position 1 of histone H4.


9,10-epoxystearate hydroxylase activity

Catalysis of the reaction: H+ + 9,10-epoxystearate + O2 + NADPH <=> 9,10-epoxy-18-hydroxystearate + H2O + NADP.


behavioral response to acetic acid induced pain

Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).


farnesol 2-isomerase activity

Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.


Catalysis of the reaction: (3R)-hydroxybutanoyl-[acyl-carrier-protein] = (2E)-butenoyl-[acyl-carrier-protein] + H2O.


embryonic root morphogenesis

The process in which the anatomical structures of the embryonic root are generated and organized.


trans-synaptic signaling by BDNF

Cell-cell signaling between presynapse and postsynapse mediated by brain-derived neurotrophic factor (BDNF) crossing the synaptic cleft.


Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+.


maintenance of RNA location

Any process in which RNA is maintained in a location and prevented from moving elsewhere.


telomeric DNA-containing double minutes formation

A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.


novofumigatonin biosynthetic process

The chemical reactions and pathways resulting in the formation of novofumigatonin, a heavily oxygenated meroterpenoid containing a unique orthoester moiety.


positive regulation of R8 cell differentiation

Any process that activates or increases the frequency, rate or extent of R8 cell differentiation.


canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin.


galactose uniporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).


acetyl-CoA catabolic process

The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.


signaling receptor ligand precursor processing

The cleavage of a peptide bond in a precursor form of a signaling receptor ligand, resulting in the mature (active) form of the ligand.


isochorismate pyruvate lyase activity

Catalysis of the reaction: isochorismate = salicylate + pyruvate.


ovarian fusome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.


regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling

Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.


regulation of aggregation involved in sorocarp development

Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.


fusion of sperm to egg plasma membrane involved in double fertilization forming a zygote and endosperm

The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of double fertilization forming a zygote and endosperm.


chemorepulsion of serotonergic neuron axon

The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.


trans-synaptic signaling by lipid

Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.


endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events.


lactoferrin receptor activity

Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.


positive regulation of muscle atrophy

Any process that activates or increases the frequency, rate or extent of muscle atrophy.


azetidine-2-carboxylic acid acetyltransferase activity

Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid.


regulation of trichome morphogenesis

Any process that modulates the frequency, rate or extent of trichome morphogenesis.


negative regulation of compound eye cone cell fate specification

Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.


ent-isokaurene C2-hydroxylase activity

Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.


endocannabinoid signaling pathway involved in trans-synaptic signaling

Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid.


negative regulation of long-term neuronal synaptic plasticity

A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.


homogalacturonan metabolic process

The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.


response to temozolomide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.


C-C chemokine receptor CCR4 signaling pathway

The series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.


positive regulation of male mating behavior

Any process that activates or increases the frequency, rate or extent of male mating behavior.


protein localization to spindle microtubule

A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.


GGA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GGA codon.


glutarate-CoA ligase activity

Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H+ + phosphate.


Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H2O + NADP+ = L-ornithine + H+ + NADPH + pyruvate.


cytoplasmic translational elongation through polyproline stretches

The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.


nicotinate dehydrogenase activity

Catalysis of the reaction: H2O + NADP+ + nicotinate = 6-hydroxynicotinate + H+ + NADPH.


microvillar actin bundle assembly

Assembly of the parallel bundle of actin filaments at the core of a microvillus.


negative regulation of cellobiose catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process.


blood coagulation, common pathway

A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.


histone H3-K56 acetylation

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone.


Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+.


trinitrophenol hydride denitratase activity

Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.


peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine

The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine.


C-C chemokine receptor CCR7 signaling pathway

The series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with the regulation of a downstream cellular process, e.g. transcription.


3-sulfino-L-alanine binding

Binding to 3-sulfino-L-alanine (cysteine sulfinate).


Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine.


positive regulation of interleukin-35-mediated signaling pathway

Any process that increases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


lipopolysaccharide glucosyltransferase II activity

Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP.


regulation of aminoacyl-tRNA ligase activity

Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity.


positive regulation of sorocarp spore cell differentiation

Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.


Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.


Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.


N-malonylurea hydrolase activity

Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H2O = H+ + malonate + urea.


response to desiccation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.


disruption of extracellular matrix of another organism

The chemical reactions and pathways performed by an organism resulting in the breakdown of the extracellular matrix of another organism.


complement component C3dg receptor activity

Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


type III hypersensitivity

An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).


chemorepulsion of dopaminergic neuron axon

The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.


L-pipecolate oxidase activity

Catalysis of the reaction: L-pipecolate + O2 = 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.


RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.


cellular response to haloperidol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.


determination of stomach left/right asymmetry

Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.


negative regulation of peptidoglycan recognition protein signaling pathway

Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


beta-carotene metabolic process

The chemical reactions and pathways involving beta-carotene.


dimethyl selenide methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium.


response to chromate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.


(1->3)-beta-D-glucan binding

Binding to a (1->3)-beta-D-glucan.


delta7-sterol 5(6)-desaturase activity

Catalysis of the reaction: a delta(7)-sterol + 2 ferrocytochrome b5 + O2 + 2 H+ -> a delta(5,7)-sterol + 2 ferricytochrome b5 + 2 H2O.


hyoscyamine (6S)-dioxygenase activity

Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O2 = (6S)-6-hydroxyhyoscyamine + CO2 + succinate.


ocellus photoreceptor cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.


protein methylthiotransferase activity

Catalysis of the reaction: 2 S-adenosyl-L-methionine + a [ribosomal protein S12] L-aspartate89 + a sulfurated [sulfur carrier] + a reduced electron acceptor = S-adenosyl-L-homocysteine + L-methionine + 5'-deoxyadenosine + 2 H+ + a [ribosomal protein S12] 3-methylthio-L-aspartate89 + an unsulfurated [sulfur carrier] + an oxidized electron acceptor.


low-affinity glucose:sodium symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


egg deposition

The multicellular organismal reproductive process that results in the movement of an egg from within an organism into the external environment.


growth hormone receptor activity

Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


effector-mediated suppression of host defense response

A process mediated by a molecule secreted by a symbiont that results in the supression of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


modulation of relaxation of muscle in another organism

The process in which an organism effects a change in the relaxation of muscle in a second organism.


N-terminal peptidyl-glycine methylation

The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.


7-beta-hydroxysteroid dehydrogenase (NADP+) activity

Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.


maintenance of left sidedness

The organization process that preserves the left sidedness in an organism's body plan or part of an organism with respect to the left and right halves.


L-cysteine catabolic process via cystine, using cysteine transaminase

The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase.


gellan lyase activity

Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).


Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose.


Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.


calcitriol binding

Binding to calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.


methylammonium transmembrane transporter activity

Enables directed movement of methylammonium, CH3NH2, from one side of a membrane to the other.


AAC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an AAC codon.


dalcochinase activity

Catalysis of the reaction: dalcochinin-8'-O-beta-glucoside + H2O <=> dalcochinin + D-glucopyranose.


Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H2O + H+.


carnitine-CoA ligase activity

Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.


endosulfan ether monooxygenase activity

Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O.


linear vestibuloocular reflex

A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.


neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration

The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.


positive adaptation of signaling pathway

The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.


protein depropionylation

The removal of a propionyl group from a residue in a peptide or protein.


keto acid formate lyase activity

Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate.


Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.


acetolactate synthase activity

Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.


Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H+ + UDP.


ketotetrose-phosphate aldolase activity

Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.


trans-cinnamate-CoA ligase activity

Catalysis of the reaction: (E)-cinnamate + ATP + CoA = (E)-cinnamoyl-CoA + AMP + diphosphate.


baicalin beta-D-glucuronidase activity

Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate.


myofibroblast contraction

The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.


antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway

The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.


deethylatrazine monooxygenase activity

Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine.


metestrus

The estrous cycle phase in which there is subsiding follicular function.


aristolochene synthase activity

Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.


Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinol-n = S-adenosyl-L-homocysteine + ubiquinol-n.


intermediate mesodermal cell fate determination

The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.


apiose biosynthetic process

The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.


larval burrowing behavior

Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.


Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H+.


hydroxylamine reductase activity

Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.


stachyose synthase activity

Catalysis of the reaction: 2 raffinose <=> stachyose + sucrose.


temporomandibular joint articular cartilage development

The process whose specific outcome is the progression of temporomandibular joint articular cartilage over time, from its formation to the mature structure.


proboscis morphogenesis, clypeo-labral disc-derived

The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.


Catalysis of the reaction: (6E)-8-hydroxygeranial + NADP <=> (6E)-8-oxogeranial + NADPH + H+.


termination of T cell signal transduction

The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.


regulation of astrocyte chemotaxis

Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.


24-ethylidenelophenol 4alpha-methyl oxidase activity

Catalysis of the reaction: 24-ethylidenelophenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O.


vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment

The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.


trans-zeatin metabolic process

The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


positive regulation of octopamine signaling pathway

Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.


anterior visceral endoderm cell migration

The orderly movement of an anterior visceral endoderm cell from one site to another.


The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose.


Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H+.


cellular response to very low light intensity stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.


dorsal closure, spreading of leading edge cells

Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa.


3-sulfolactaldehyde reductase activity

Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.


cystathionine gamma-synthase activity (acts on O-phosphohomoserine)

Catalysis of the reaction: L-cysteine + O-phosphonato-L-homoserine = L-cystathionine + hydrogenphosphate.


peptidyl-proline di-hydroxylation

The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.


heterocyclic compound binding

Binding to heterocyclic compound.


Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.


cytochrome c biosynthetic process

The chemical reactions and pathways resulting in the formation of cytochrome c.


cell-cell adhesion involved in synapse maturation

The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.


interleukin-28B production

The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


furylfuramide isomerase activity

Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.


accessory nerve morphogenesis

The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


methylguanosine-cap decapping

Cleavage of the 5'-methylguanosine-cap of an mRNA. The methylguanosine-cap is present at the 5'-end of eukaryotic mRNAs. Decapping inactivates translation initiation and promotes 5'-to-3' decay of mRNA.


negative regulation of imaginal disc-derived wing size

Any process that reduces the size of an imaginal disc-derived wing.


protopanaxadiol 6-hydroxylase activity

Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O.


regulation of viral DNA genome packaging via site-specific sequence recognition

Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.


Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.


regulation of cell population proliferation

Any process that modulates the frequency, rate or extent of cell proliferation.


response to diterpene

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.


benzaldehyde dehydrogenase (NADP+) activity

Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.


cinnamic acid metabolic process

The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.


hippocampal interneuron differentiation

The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.


L-lysine efflux transmembrane transporter activity

Enables the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.


Catalysis of the reaction: 1-18:1-2-trans-16:1-phosphatidylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-trans-16:1-phosphatidylglycerol + 2 H2O + an oxidized electron acceptor.


glycosylceramide flippase activity

Catalysis of the movement of glycosylceramide from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP. Glycosylceramides are ceramides containing a functional group derived from a sugar.


Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.


sternite morphogenesis

The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment.


(R)-mevalonic acid metabolic process

The chemical reactions and pathways involving (R)-mevalonic acid.


indole glucosinolate biosynthetic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.


phosphocreatine biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.


negative regulation of cell proliferation in dorsal spinal cord

Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.


mannitol transmembrane transporter activity

Enables the transfer of mannitol from one side of a membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.


Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.


neuropeptide processing

Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a neuropeptide precursor. Processing leads to the attainment of the full functional capacity of the neuropeptide.


Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.


negative regulation of male germ-line stem cell asymmetric division

Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division.


putrescine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H+.


proteasomal proteolysis associated with antigen processing and presentation

The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.


low-affinity IgA receptor activity

Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


negative regulation of oligodendrocyte progenitor proliferation

Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.


positive regulation of midbrain dopaminergic neuron differentiation

Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.


hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles

Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.


Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+.


positive regulation of cellotriose catabolic process

Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process.


ABC-type D-galactofuranose transporter

Catalysis of the reaction: alpha-D-galactofuranose + ATP + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP + H+.


negative regulation of CD8-positive, alpha-beta T cell extravasation

Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.


establishment of septation initiation network asymmetry

The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies.


regulation of phosphate transmembrane transport

Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.


carbapenem biosynthetic process

The chemical reactions and pathways resulting in the formation of carbapenem.


glycerol-1-phosphate dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.


catechol 1,2-dioxygenase activity

Catalysis of the reaction: catechol + O2 = cis,cis-muconate.


helvolic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of helvolic acid.


tetrose metabolic process

The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.


4-hydroxybenzoate-CoA ligase activity

Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.


tocopherol O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol.


trans-synaptic signaling by neuropeptide, modulating synaptic transmission

Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.


cellular response to tropane

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.


butirosin metabolic process

The chemical reactions and pathways involving butirosin.


negative regulation of GABA-A receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of GABA-A receptor activity.


gibberellin A4 16alpha,17 epoxidase activity

Catalysis of the reaction: gibberellin A4 + O2 + H+ + NAD(P)H <=> 16alpha,17-epoxy gibberellin A4 + H2O + NAD(P).


iduronate-2-sulfatase activity

Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.


response to cobalamin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.


Catalysis of the reaction: UDP-glucose + ergosterol = UDP + O-glucosyl-ergosterol.


vicianin beta-glucosidase activity

Catalysis of the reaction: (R)-vicianin + H2O = mandelonitrile + vicianose.


GMP synthase (glutamine-hydrolyzing) activity

Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H+.


diacetyl reductase ((R)-acetoin forming) activity

Catalysis of the reaction: (R)-acetoin + NAD+ = diacetyl + H+ + NADH.


histone H3K9 dimethyltransferase activity

Catalysis of the reaction: L-lysyl9-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl9-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me2.


positive regulation of complement activation, alternative pathway

Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway.


negative regulation of paraxial mesodermal cell fate determination

Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.


modulation by host of symbiont type IV pilus-dependent motility

The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


entry into host cell by a symbiont-containing vacuole

The invasion by a symbiont of a cell of a host organism, forming a vacuole in which the symbiont resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole.


L-sorbose biosynthetic process

The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.


peptidyl-lysine guanylylation

The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine.


negative regulation of voltage-gated calcium channel activity in another organism

Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


biosynthetic process of antibacterial peptides active against Gram-positive bacteria

The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.


The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate.


isonocardicin synthase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H+ + isonocardicin A.


positive regulation of neuronal action potential

Any process that activates or increases the frequency, rate or extent of neuronal action potential.


cellular response to cycloalkane

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.


macromolecule modification

The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.


cellular response to freezing

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


histone H3K deacetylase activity

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine + H2O = histone H3 L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone H3.


xylose isomerase activity

Catalysis of the reaction: D-xylose = D-xylulose.


Catalysis of the reaction: (S)-naringenin + S-adenosyl-L-methionine = 2 H+ + ponciretin + S-adenosyl-L-homocysteine.


perchlorate reductase activity

Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O.


modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade

Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


taxis to electron acceptor

The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate.


GUG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GUG codon.


U2 snRNP binding

Binding to a U2 small nuclear ribonucleoprotein particle.


regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.


natural killer cell inhibitory signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.


carveol dehydrogenase activity

Catalysis of the reaction: (1S,5R)-carveol + NADP+ = (R)-carvone + H+ + NADPH.


Notch signaling pathway involved in forebrain neuroblast division

The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.


albendazole monooxygenase activity

Catalysis of the reaction: albendazole + H+ + NADPH + O2 = albendazole S-oxide + H2O + NADP+.


left ventricular compact myocardium morphogenesis

The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.


prostaglandin catabolic process

The chemical reactions and pathways resulting in the breakdown of prostaglandin.


regulation of biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.


regulation of hemicellulose catabolic process

Any process that modulates the frequency, rate or extent of hemicellulose catabolic process.


vasodilation involved in acute inflammatory response

An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response.


lactoyl-CoA dehydratase activity

Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.


Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP+ + phosphate = L-glutamyl 5-phosphate + H+ + NADPH.


FAD-dependent urate hydroxylase activity

Catalysis of the reaction: 7,9-dihydro-1H-purine-2,6,8(3H)-trione + NADH + H+ + O2 <=> 5-hydroxyisouric acid + NAD + H2O.


positive regulation of cardiac epithelial to mesenchymal transition

Any process that starts or increases the rate, frequency or extent of cardiac epithelial to mesenchymal transition, a transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.


Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H+.


lipopolysaccharide transmembrane transporter activity

Enables the transfer of lipopolysaccharides from one side of a membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.


negative regulation of collecting lymphatic vessel constriction

Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction.


cysteine-type exopeptidase activity

Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


D-leucine catabolic process

The chemical reactions and pathways resulting in the breakdown of D-leucine.


acetate fermentation

The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.


anthocyanin-containing compound metabolic process

The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers.


substituted mannan metabolic process

The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units.


DIF dechlorinase activity

Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-.


detection of maltose stimulus

The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.


Catalysis of the reaction: 2,4',7-trihydroxyisoflavanone + S-adenosyl-L-methionine <=> H+ + 2,7-dihydroxy-4'-methoxyisoflavanone + S-adenosyl-L-homocysteine.


somatic diversification of immune receptors via gene conversion

The process in which immune receptor genes are diversified through gene conversion.


ADP-thymidine kinase activity

Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.


embryonic ectodermal digestive tract morphogenesis

The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.


Catalysis of the reaction: GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate = GDP-4-dehydro-6-deoxy-alpha-D-mannose + L-glutamate.


positive regulation of maltotriulose transport

Any process that activates or increases the frequency, rate or extent of maltotriulose transport.


integrated stress response signaling

The series of molecular signals generated in response to diverse stress stimuli required to restore cellular homeostasis. The core event in this pathway is the phosphorylation of eIF2 alpha by one of four members of the eIF2a kinase family (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2), which leads to a decrease in global protein synthesis and the induction of selected genes, including the transcription factor ATF4, that together promote cellular recovery.


modification by virus of host cell cycle regulation

Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication.


O-succinyltransferase activity

Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.


proteasome core complex assembly

The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.


spinal cord interneuron axon guidance

The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.


nuclear capsid assembly

The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.


Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA(Ala) = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA(Ala).


regulation of septation initiation signaling

Any process that modulates the frequency, rate or extent of septation initiation signaling.


ion binding

Binding to an ion, a charged atoms or groups of atoms.


determination of intestine left/right asymmetry

Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.


Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.


hexitol dehydrogenase activity

Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor.


detection of folic acid

The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal.


negative regulation of otic vesicle morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.


histone succinylation

The modification of a histone by the addition of an succinyl group.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monocarboxylate(out) + Na+(out) = monocarboxylate(in) + Na+(in).


glucuronoside transmembrane transporter activity

Enables the transfer of a glucuronosides from one side of a membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.


interferon-epsilon production

The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


response to cyclopentenone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.


positive regulation of cilium movement

Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.


haltere development

The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.


homoserine biosynthetic process

The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.


zygotene

The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.


planar cell polarity pathway involved in ventricular septum morphogenesis

The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.


L-tryptophan transmembrane transporter activity

Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.


5-aminolevulinate-CoA ligase activity

Catalysis of the reaction: 5-ammoniolevulinate + coenzyme A + ATP <=> 5-aminolevulinyl-CoA + AMP + diphosphoric acid.


single-strand selective uracil DNA N-glycosylase activity

Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.


iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide

The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide.


copal-8-ol diphosphate synthase activity

Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O.


UDP-D-glucose:delphinidin 3-O-glucosyl-5-O-caffeoylglucoside -O-beta-D-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + delphinidin 3-O-glucosyl-5-O-caffeoylglucoside <=> H+ + delphinidin 3-O-glucosyl-5-O-(caffeoylglucoside-3'-O-glucoside) + UDP.


fungal-type cell wall (1->3)-beta-D-glucan metabolic process

The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi.


positive regulation of positive thymic T cell selection

Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection.


rolling circle viral DNA replication

A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.


suppression by symbiont of host cell-mediated immune response

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


apical dendrite arborization

The process in which the anatomical structures of a dendritic tree are generated on the apical neuron side and organized into dendritic branches.


maltose glucosidase activity

Catalysis of the reaction: H2O + maltose = 2 glucose.


negative regulation of branch elongation involved in ureteric bud branching

Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.


negative regulation of microglia differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.


light-independent chlorophyll biosynthetic process

The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.


response to strigolactone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.


quinate 3-dehydrogenase (NAD+) activity

Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.


negative energy taxis

The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.


callose deposition in cell wall

Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.


Catalysis of the reaction: 7,8-dihydroxykynurenate + O2 = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H+.


seed maturation

A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.


transmembrane ascorbate ferrireductase activity

Oxidation of Fe(3+) to Fe(2+) on the outer side of a membrane coupled to the reduction of L-ascorbate to monodehydro-L-ascorbate radical on the inner side of a membrane. Electrons get transferred across the membrane during the reaction.


p-benzoquinone reductase (NADPH) activity

Catalysis of the reaction: 1,4-benzoquinone + H+ + NADPH = hydroquinone + NADP+.


cell proliferation involved in pronephros development

The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.


establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration

Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.


positive regulation of spore encystment on host

Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


ascaroside metabolic process

The chemical reactions and pathways involving ascaroside.


arginine N-succinyltransferase activity

Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine.


sterigmatocystin metabolic process

The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.


nucleoside oxidase (hydrogen peroxide-forming) activity

Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide.


anaerobic cyclohexane-1-carboxylate catabolic process

The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.


positive regulation of platelet-derived growth factor receptor-beta signaling pathway

Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.


positive regulation of ureter smooth muscle cell differentiation

Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.


hydroxyquinol 1,2-dioxygenase activity

Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate.


terpene catabolic process

The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.


morphogenesis of an epithelial fold involved in embryonic heart tube formation

The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.


oral incubation

A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.


chondrocyte activation

A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.


glucan 1,6-alpha-glucosidase activity

Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.


butanediol catabolic process

The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


thiol-driven fumarate reductase activity

Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.


positive regulation of L-methionine import across plasma membrane

Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane.


positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process

Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.


negative regulation of complement activation, alternative pathway in another organism

Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.


pyrimidine deoxyribonucleotide binding

Binding to a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


L-methionine secondary active transmembrane transporter activity

Enables the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.


determination of left/right asymmetry in nervous system

The establishment of the nervous system with respect to the left and right halves.


envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism.


chondrocyte intercalation involved in growth plate cartilage morphogenesis

The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.


positive regulation of motor neuron apoptotic process

Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.


peptide cross-linking via L-alanyl-5-imidazolinone glycine

The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.


inositol heptakisphosphate 5-kinase activity

Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.


monodehydroascorbate reductase (NADH) activity

Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.


oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound.


squalene synthase activity

Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.


Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.


7-oxatyphasterol synthase activity

Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O.


adult visceral muscle development

The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.


nicotianamine metabolic process

The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


Catalysis of the reaction: all-trans-beta-carotene + O2 = 2 all-trans-retinal.


Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.


anaerobic catabolism of pairs of amino acids

The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.


chemokine (C-C motif) ligand 1 production

The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


hemocyte development

The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.


guanidinobutyrase activity

Catalysis of the reaction: 4-guanidinobutanoate + H2O = 4-aminobutanoate + urea.


mesenchymal stem cell proliferation

The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


zeinoxanthin epsilon hydroxylase activity

Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.


trimethyluric acid monooxygenase activity

Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O.


tetrahydrocorphin metabolic process

The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.


negative regulation of ornithine catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.


histone H2B acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.


caudal fin morphogenesis

The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.


peptide cross-linking via an oxazole or thiazole

The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


negative regulation of meiotic joint molecule formation

Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.


pyochelin biosynthetic process

The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).


Catalysis of the reaction: H+ + uracil 5-carboxylate = CO2 + uracil.


L-lysine 4-chlorinase activity

Catalysis of the reaction: 2-oxoglutarate + chloride + H+ + L-lysine + O2 = 4-chloro-L-lysine + CO2 + H2O + succinate.


tyrosine phenol-lyase activity

Catalysis of the reaction: L-tyrosine + H2O = NH4 + phenol + pyruvate.


propane-1,3-diamine oxidase activity

Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+.


alpha-1,4-mannosyltransferase activity

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.


thiosulfate transmembrane transporter activity

Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.


9,12-cis-hexadecadienoic acid delta 15 desaturase activity

Catalysis of the reaction: (9Z,12Z)-hexadecadienoyl-CoA + O2 + a reduced electron acceptor <=> 9,12,15-cis-hexadecatrienoyl-CoA + 2 H2O + an oxidized electron acceptor.


Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H+.


GDP-glucosidase activity

Catalysis of the reaction: GDP-D-glucose + H2O = D-glucose + GDP + H+.


epithelial cell migration involved in distal tubule morphogenesis

The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.


chlorobenzene dioxygenase activity

Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).


Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO2 + H+ + isopentenyl diphosphate + phosphate.


Catalysis of the reaction: 4-guanidinobutanal + H2O + NAD+ = 4-guanidinobutanoate + 2 H+ + NADH.


endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.


The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.


tagatose-6-phosphate kinase activity

Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.


vitamin D4 metabolic process

The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.


versicolorin B desaturase activity

Catalyzes the reaction: versicolorin B + NADPH + O2 <=> versicolorin A + NADP+ + 2 H2O. Uses heme-thiolate as a co-factor. Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.


Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.


Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.


decanoyl-[acp] 2-dehydrogenase activity

Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein = FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF.


Catalysis of the reaction: icosanoyl-CoA + dodecan-1-ol = arachidoyl dodecanoate + coenzyme A.


neural crest-derived cardiac glial cell development

The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


Catalysis of the reaction: 2,3-dihydroxybenzoate + O2 = 2-carboxy-cis,cis-muconate + 2 H+.


G-protein gated monoatomic ion channel activity

An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.


regulation of ferrochelatase activity

Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.


positive regulation by symbiont of abscisic acid levels in host

Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


lactate catabolic process

The chemical reactions and pathways resulting in the breakdown of lactate.


Catalysis of the reaction: 1-16:0-2-18:2-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


mesoderm structural organization

The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.


viral tail assembly

The aggregation, arrangement and bonding together of a set of components to form a virus tail.


negative regulation of vesicle transport along microtubule

Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.


alpha-N-acetylglucosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.


chemorepulsion of branchiomotor neuron axon in neural tube

The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


neuron projection arborization

The process in which the anatomical structures of a neuron projection are generated and organized into branches. A neuron projection is any process extending from a neural cell, such as axons or dendrites.


3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity

Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.


positive regulation of sevenless signaling pathway

Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.


selenocysteine catabolic process

The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.


response to cell size control checkpoint signaling

A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.


transcription elongation by mitochondrial RNA polymerase

The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.


occlusion by symbiont of host xylem

The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.


chloromuconate cycloisomerase activity

Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.


evasion by virus of host natural killer cell activity

Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells.


transmembrane signaling receptor activity

Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


positive regulation of ecdysteroid secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.


positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine

Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.


Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.


temperature compensation of the circadian clock

The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.


negative regulation of interleukin-18-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.


histone H2B-K5 acetylation

The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone.


positive regulation of retinal cell programmed cell death

Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).


epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification

Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.


Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.


ERBB2-ERBB4 signaling pathway

The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.