telomeric repeat-containing RNA transcription

The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.


regulation of imaginal disc growth

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.


chemokine (C-X-C motif) ligand 1 production

The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


negative regulation of salivary gland boundary specification

Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.


TDP catabolic process

The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.


positive regulation of histamine uptake

Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.


negative regulation of hepatic stellate cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.


suppression by virus of host mRNA export from nucleus

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.


induction of programmed cell death by ecdysone

Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.


maintenance of protein location in T cell secretory granule

A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


specification of mesonephric tubule identity

The process in which the tubules of the mesonephros acquire their identity.


peripheral tolerance induction to self antigen

Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.


flavone synthase activity

Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.


cellular response to interleukin-18

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.


inositol phosphorylceramide synthase activity

Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol.


catechol oxidase (dimerizing) activity

Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.


metanephric nephron epithelium development

The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.


regulation of age-related resistance

Any process that modulates the extent of age-related resistance.


positive regulation of cellular response to oxidopamine

Any process that activates or increases the frequency, rate or extent of cellular response to oxidopamine.


antibacterial peptide production

The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.


ATP deaminase activity

Catalysis of the reaction: ATP + H2O = ITP + NH3.


positive regulation of venous endothelial cell fate commitment

Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment.


verruculogen metabolic process

The chemical reactions and pathways involving verruculogen.


cardiac muscle myosin thick filament assembly

The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.


sulfide oxidation, using sulfide dehydrogenase

A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase.


parathion catabolic process

The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.


mitochondrial polycistronic RNA processing

The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs.


4-hydroxyindole-3- carbonyl nitrile biosynthesis

The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside.


secondary leaflet morphogenesis

The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.


regulation of torso signaling pathway

Any process that modulates the frequency, rate or extent of the torso signaling pathway.


cell adhesion involved in sprouting angiogenesis

The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the formation of a blood vessel network.


positive regulation of posterior neural plate formation by Wnt signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation.


carbon phosphorus lyase activity

Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).


gibberellin A4 carboxyl methyltransferase activity

Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine.


The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


positive regulation of laminaritriose transport

Any process that activates or increases the frequency, rate or extent of laminaritriose transport.


Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol.


dorsal appendage formation

Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.


limonoid glucosyltransferase activity

Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.


sphingolipid transfer activity

Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


ACC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an ACC codon.


response to paracetamol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.


Wnt-activated signaling pathway involved in forebrain neuron fate commitment

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.


maleate isomerase activity

Catalysis of the reaction: maleate = fumarate.


intracellular nucleoside homeostasis

A homeostatic process involved in the maintenance of a steady state level of nucleosides within a cell.


optomotor response

Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.


T-helper 1 cell diapedesis

The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine.


modification-dependent macromolecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.


UUU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UUU codon.


arylsulfate sulfotransferase activity

Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.


purine ribonucleoside biosynthetic process

The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.


envenomation resulting in negative regulation of complement activation, alternative pathway in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism.


bacteriocin biosynthetic process

The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.


peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid

The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid.


emodin metabolic process

The chemical reactions and pathways involving emodin.


aminoglycoside antibiotic metabolic process

The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


sterol 24-C-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol.


regulation of pole plasm oskar mRNA localization

Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.


regulation of growth plate cartilage chondrocyte proliferation

Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.


pre-B cell receptor expression

The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, starting with the recombination of an immunuglobulin heavy chain locus, including expression of the surrogate light chain, the association of the surrogate light chain with the heavy chain, and expression of the complete pre-B cell receptor on the cell surface. pre-B cell receptor expression is a key checkpoint in the transition of pro-B cell to pre-B cell.


Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O.


induction by symbiont of host I-kappaB kinase/NF-kappaB cascade

Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


positive regulation of dauer entry

Any process that activates or increases the frequency, rate or extent of dauer entry.


Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.


regulation of Hulle cell development

Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


extracellular microvesicle biogenesis

The assembly and secretion of a set of components to form an extracellular microvesicule, a membrane-bounded vesicle that ranges in size 100 nm to 1 micron in size) and exits the cell by budding.


Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H+ + taxiphyllin + UDP.


somatic diversification of immune receptors via alternate splicing

The process in which immune receptor genes are diversified through alternate splicing.


Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.


sensory perception of humidity

The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.


floral organ formation

The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.


response to tetracycline

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.


riboflavin reductase (NAD(P)H) activity

Catalysis of the reaction: reduced riboflavin + NAD(P)+ = riboflavin + NAD(P)H + 2 H+. This reaction can utilize NADH and NADPH.


Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H+ + phosphate.


Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide.


amino sugar biosynthetic process

The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.


low-affinity IgM receptor activity

Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


glutathione S-conjugate carboxypeptidase activity

Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate.


regulation of Ran protein signal transduction

Any process that modulates the frequency, rate or extent of Ran protein signal transduction.


pole plasm assembly

Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.


6-methylthiopropyl glucosinolate S-oxygenase activity

Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.


neural crest-derived cardiac glial cell fate commitment

The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.


spinal cord association neuron specification

The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.


ulvan lyase activity

Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.


negative regulation of smooth muscle hypertrophy

Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.


negative regulation of sclerotium development

Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development.


cellular response to trichodermin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.


larynx development

The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration.


neuroblast division in dorsal lateral ganglionic eminence

The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.


mesonephric renal vesicle formation

The developmental process pertaining to the initial formation of the mesonephros.


Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.


RNA polymerase II CTD heptapeptide repeat modifying activity

A catalytic activity that acts on the RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS). Reversible modifications cof the RNA polymerase II CTD repeats contribute to regulation of RNA polymerase activity.


response to zinc ion starvation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion.


peptidyl-threonine sulfation

The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.


3-HSA hydroxylase activity

Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.


regulation of toll-like receptor 5 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


activated CD8-positive, alpha-beta T cell proliferation

The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.


effector-mediated induction of cell cycle reactivation in host

A symbiont process in which a molecule secreted by the symbiont reactivates the host cell cycle, resulting in DNA synthesis and host cell division, and contributing to vegetative tumor formation.


tectobulbar tract morphogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.


cholate 12-alpha dehydrogenase activity

Catalysis of the reaction: cholate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H+ + NADPH.


lipoprotein biosynthetic process via diacylglyceryl transfer

The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex.


detection of ethylene stimulus

The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.


ciliary vesicle assembly

The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.


peptide cross-linking via glycine thiazolecarboxylic acid

The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


octopamine dehydratase activity

Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH4.


negative regulation of RNA binding transcription factor activity

Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity.


galactose oxidase activity

Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.


Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


long-day photoperiodism, flowering

A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.


Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.


cellular response to phylloquinone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.


glycerol 2-dehydrogenase (NADP+) activity

Catalysis of the reaction: glycerol + NADP+ = glycerone + H+ + NADPH.


Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.


muscle adaptation

A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.


S-triazine hydrolase activity

Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.


regulation of glucuronoarabinoxylan catabolic process

Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.


resolution phase response

An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.


regulation of systemic arterial blood pressure by stress relaxation

The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.


positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.


effector-mediated modulation of host process by symbiont

A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.


G protein-coupled chemorepellent receptor activity

Combining with a chemorepellent and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin.


3'-O-methyltricetin O methyl transferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin.


cellular response to catechin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.


amino acid ligation activity by nonribosomal peptide synthase

Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.


regulation of nuclease activity

Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


regulation of flavonoid biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.


protein O-linked glycosylation via hydroxylysine

The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.


UDP-D-apiose metabolic process

The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


norepinephrine-epinephrine catabolic process in blood stream

The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.


cinnamate reductase activity

Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+.


glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.


cerebellar basket cell differentiation

The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.


uracil dehydrogenase activity

Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.


keto-3-deoxy-D-manno-octulosonic acid metabolic process

The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.


negative regulation of axial mesodermal cell fate determination

Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.


saponin biosynthetic process

The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.


abscisic acid glucose ester beta-glucosidase activity

Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.


positive regulation of phosphatidylethanolamine metabolic process

Any process that activates or increases the frequency, rate or extent of phosphatidylethanolamine metabolic process.


oviduct morphogenesis

The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.


alanopine dehydrogenase activity

Catalysis of the reaction: 2,2'-iminodipropanoate + H2O + NAD+ = L-alanine + H+ + NADH + pyruvate.


The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.


(25S)-Delta(4)-dafachronate binding

Binding to (25S)-Delta(4)-dafachronate.


subpallium cell proliferation in forebrain

The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.


rRNA acetylation

The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


thyroid-stimulating hormone-secreting cell development

The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.


UDP-rhamnose biosynthetic process

The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide

The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.


disruption by symbiont of host cell-cell adhesion

The process by which a symbiont disupts cell-cell adhesion in its host.


negative regulation of turning behavior involved in mating

Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.


neoxanthin synthase activity

Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.


chaeta morphogenesis

The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.


reduced coenzyme F420:quinone oxidoreductase activity

Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone.


GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity

Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.


CoB--CoM heterodisulfide reductase activity

Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.


The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.


negative regulation of entry into reproductive diapause

Any process that stops, prevents, or reduces the frequency, rate or extent of the dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.


mesonephric glomerulus vasculature morphogenesis

The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.


agglutination involved in conjugation with cellular fusion

The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae.


sequestering of mercury

The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.


phenylmercury acetate catabolic process

The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.


regulation of cardiac endothelial to mesenchymal transition

Any process that modulates the frequency, rate or extent of cardiac endothelial to mesenchymal transition.


peptidyl-tryptophan modification

The chemical alteration of a tryptophan residue in a peptide.


[tyrosine 3-monooxygenase] kinase activity

Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase].


inferior olivary nucleus maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.


regulation of flocculation

Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.


pyridoxal oxidase activity

Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.


AUA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an AUA codon.


trichloro-p-hydroquinone reductive dehalogenase activity

Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl.


response to triacyl bacterial lipopeptide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.


lymphocyte activation involved in immune response

A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.


Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole.


glomerulus vasculature morphogenesis

The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.


dicarboxylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.


positive regulation of heart looping

Any process that activates or increases the frequency, rate or extent of heart looping.


prephenate(2-) biosynthetic process

The chemical reactions and pathways resulting in the formation of prephenate(2-).


cellular response to cell envelope stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope.


NADPH dehydrogenase activity

Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.


Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A.


acetoacetyl-ACP synthase activity

Catalysis of the reaction: acetyl-CoA + malonyl-CoA + H+ + a holo-[acyl-carrier protein] <=> acetoacetyl-ACP + 2 coenzyme A + carbon dioxide.


siRNA-mediated retrotransposon silencing by mRNA destabilization

A retrotransposon silencing mechanism in which mRNAs transcribed from transposons are targeted for degradation by a siRNA.


response to cell cycle checkpoint signaling

A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.


dTDP-mannose metabolic process

The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.


maintenance of secretory granule location

Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.


root cap development

The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.


2-hydroxyeriodictyol 6C-glucoside dehydratase activity

Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O.


positive regulation of Notch signaling pathway involved in heart induction

Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.


phosphate:acyl-[acyl carrier protein] acyltransferase activity

Catalysis of the reaction: a fatty acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein].


negative regulation of austinol biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process.


multiple spine synapse organization, multiple dendrites

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse between a multiple synapse bouton and two or more dendritic spines protruding either from a single dendrite or from multiple dendrites.


positive regulation of bone remodeling

Any process that activates or increases the frequency, rate or extent of bone remodeling.


polyketide synthase activity

Catalysis of a multistep reaction that produce polyketides through decarboxylative condensation of carboxylic acids. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core chain-elongation domains are variable numbers of auxiliary domains that are responsible for modification of the growing polypeptide chain by a small set of iterated reactions including epimerization, N-methylation, and heterocyclization.


pentanamidase activity

Catalysis of the reaction: H2O + pentanamide = NH4 + valerate.


tRNA m2,2-guanine biosynthesis

The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.


canonical Wnt signaling pathway involved in heart development

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.


negative regulation of xylan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process.


solanapyrone synthase activity

Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A.


positive regulation of nervous system development

Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.


ATPase-coupled monocarboxylic acid transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).


snRNA modification guide activity

Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.


Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.


efferent axon development in anterior lateral line nerve

The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.


GPCR taste receptor activity

A G protein-coupled receptor activity that is responsible for the sense of taste.


oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.


negative regulation of lateral mesodermal cell fate specification

Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.


dendritic cell cytokine production

Any process that contributes to cytokine production by a dendritic cell.


positive regulation of nutrient release by host

Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


interleukin-5 production

The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


cellular response to quercetin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.


cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)

Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.


palmitic acid metabolic process

The chemical reactions and pathways involving palmitic acid.


defense response by callose deposition in cell wall

Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.


positive regulation of cyclodextrin metabolic process

Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process.


leucoanthocyanidin biosynthetic process

The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.


maintenance of unfolded protein

Maintaining a protein in an unfolded, soluble state.


B-1b B cell differentiation

The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.


oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.


mannose catabolic process

The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.


regulation of dendritic cell antigen processing and presentation

Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.


outer stripe development

The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.


Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA + H+.


negative regulation of methanofuran metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process.


bisphenol A hydroxylase B activity

Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.


glycine reductase activity

Catalysis of the reaction: acetyl phosphate + H2O + NH4 + thioredoxin disulfide = glycine + H+ + phosphate + thioredoxin.


negative regulation of mitotic spindle pole body separation

Any process that decreases the rate, frequency or extent of the process involving the release of duplicated mitotic spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.


D-lysine oxidase activity

Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide.


specification of mesonephric distal tubule identity

The process in which the distal tubule of the mesonephric nephron acquires its identity.


positive regulation of heart rate by neuronal norepinephrine

The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction.


regulation of secretion by cell

Any process that modulates the frequency, rate or extent of secretion by cell.


cellotetraose binding

Binding to a cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.


trinitrophenol dihydride denitratase activity

Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.


positive regulation of paraxial mesodermal cell fate specification

Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.


Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate.


alcohol O-decanoyltransferase activity

Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester.


eisosome assembly

The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane and eisosome filaments. The eisosome membrane, also called the MCC domain, is a furrow-like plasma membrane sub-domain with associated integral transmembrane proteins. The eisosome filaments form a scaffolding lattice on the cytoplasmic face of the membrane.


positive regulation of relaxation of smooth muscle

Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle.


cellulose binding

Binding to cellulose.


isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate

The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate.


envenomation resulting in modulation of calcium channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism.


negative regulation of multicellular organismal process

Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.


sequestering of copper ion

The process of binding or confining copper ions such that they are separated from other components of a biological system.


positive regulation of mechanosensory behavior

Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.


flavonol binding

Binding to a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.


positive regulation of apoptotic process involved in metanephric nephron tubule development

Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.


delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity

Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+.


Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate.


acquisition of desiccation tolerance

The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.


D-xylose 1-dehydrogenase (NAD) activity

Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.


regulation of NK T cell activation

Any process that modulates the frequency, rate or extent of natural killer T cell activation.


UDP-glucose:curcumin monoglucoside glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + curcumin monoglucoside = H+ + curcumin diglucoside + UDP.


positive regulation of serotonin uptake

Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.


bract morphogenesis

The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.


sepal formation

The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.


ferric-enterobactin transmembrane transporter activity

Enables the transfer of ferric-enterobactin from one side of a membrane to the other.


Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2.


leg disc development

Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.


Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.


specification of proximal tubule identity

The process in which the proximal tubule of the kidney nephron acquires its identity.


clearance of cells from fusion plate

The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.


nitronate monooxygenase (FMN-linked) activity

Catalysis of the reaction: ethylnitronate + FMNH(2) + O2 = acetaldehyde + FMN + H2O + H+ + nitrite.


polyprenol metabolic process

The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.


Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.


glycerolipid biosynthetic process

The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.


neurotransmitter metabolic process

The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity

Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.


5-(carboxyamino)imidazole ribonucleotide synthase activity

Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H+ + phosphate.


Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol.


Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine.


phenanthrene catabolic process

The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.


Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.


TMP metabolic process

The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.


iodide oxidation

The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.


Catalysis of the reaction: 4alpha-formyl-5alpha-cholesta-7,24-dien-3beta-ol + O2 + NADH(2-) <=> 4alpha-carboxy-5alpha-cholesta-7,24-dien-3beta-ol + NAD(1-) + H2O.


positive regulation of meiotic cell cycle process involved in oocyte maturation

Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.


proximal/distal pattern formation, imaginal disc

The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.


questin monooxygenase activity

Catalysis of the reaction: H+ + NADPH + O2 + questin = demethylsulochrin + NADP+.


senecionine N-oxygenase activity

Catalysis of the reaction: H+ + NADPH + O2 + senecionine = H2O + NADP+ + senecionine N-oxide.


regulation of hepatic stellate cell contraction

Any process that modulates the frequency, rate or extent of hepatic stellate cell contraction.


cellular detoxification of sulfide

Any process carried out at the cellular level that reduces or removes the toxicity of a sulfide. These may include chemical modification or transport of sulfide away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


regulation of vasoconstriction by neuronal epinephrine

Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings.


oxaloacetase activity

Catalysis of the reaction: H2O + oxaloacetate = acetate + H+ + oxalate.


positive regulation of steroid metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.


N-terminal peptidyl-leucine methylation

The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine.


alkane transmembrane transporter activity

Enables the transfer of alkanes from one side of a membrane to the other. Alkanes are saturated aliphatic hydrocarbon compounds.


peptidyl-cysteine phosphorylation

The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine.


mesonephric smooth muscle tissue development

The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.


tricellular tight junction disassembly

The disaggregation of a tricellular tight junction into its constituent components.


modification by virus of host mRNA processing

Any viral process that interferes with the processing of mRNA in the host cell.


beta-galactofuranosidase activity

Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.


isofucosterol hydroxylase activity

Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP.


Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine.


delta-carotene metabolic process

The chemical reactions and pathways involving delta-carotene.


Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H+.


demethoxycurcumin synthase

Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide.


protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine

The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).


carotenoid catabolic process

The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.


hexuronate:monoatomic cation symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.


regulation of adaptive immune effector response

Any process that modulates the frequency, rate or extent of adaptive immune effector response.


dihydroorotate dehydrogenase (NADPH) activity

Catalysis of the reaction: (S)-dihydroorotate + NADP+ = H+ + NADPH + orotate.


chemokine (C-C motif) ligand 19 production

The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


xylitol kinase activity

Catalysis of the reaction: ATP + xylitol = ADP + 2 H+ + xylitol 5-phosphate.


gibberellin A20,2-oxoglutarate:oxygen oxidoreductase activity

Catalysis of the reaction: gibberellin A20 + 2-oxoglutarate + O2 <=> gibberellin A29 + succinate + carbon dioxide.


clathrin coating of Golgi vesicle, plasma membrane to endosome targeting

The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.


lactone catabolic process

The chemical reactions and pathways resulting in the breakdown of lactone.


flurbiprofen binding

Binding to flurbiprofen.


ATP-dependent H3-H4 histone complex chaperone activity

A histone chaperone that carries a H3-H4 histone complex, driven by ATP hydrolysis.


protein guanylyltransferase activity

Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.


Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment

Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment.


cardiac muscle cell fate determination

The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


beta-L-Ara4N-lipid A biosynthetic process

The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.


negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure

Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.


The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage.


positive regulation of adult salivary gland boundary specification

Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.


polysaccharide immune receptor activity

Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


in-chain hydroxy fatty acyl-CoA synthetase activity

Catalysis of the reaction: coenzyme A + ATP + an in-chain hydroxy fatty acid = diphosphoric acid + AMP + a in-chain hydroxyacyl-CoA.


zymosterol metabolic process

The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).


regulation of estrogen secretion

Any process that modulates the frequency, rate or extent of estrogen secretion.


regulation of juvenile hormone secretion

Any process that modulates the frequency, rate or extent of juvenile hormone secretion.


regulation of eosinophil activation

Any process that modulates the frequency, rate or extent of eosinophil activation.


peptide cross-linking via L-serine thiazolecarboxylic acid

The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.


regulation of xanthophore differentiation

Any process that modulates the frequency, rate or extent of xanthophore differentiation.


epidermis morphogenesis involved in nipple formation

The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.


naringenin-chalcone synthase activity

Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.


alpha-copaene metabolic process

The chemical reactions and pathways involving alpha-copaene.


meiotic telophase II

The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.


cephamycin C metabolic process

The chemical reactions and pathways involving cephamycin C.


voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.


exit from dormancy

The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.


methyl transfer-driven active transmembrane transporter activity

Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.


respiratory chain complex III assembly

The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.


regulation of paraxial mesodermal cell fate determination

Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.


regulation of premature acrosome loss

Any process that modulates the rate, frequency or extent of the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


negative regulation of monoatomic anion transport

Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.


negative regulation of nuclear migration during mitotic telophase

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.


regulation of octopamine signaling pathway involved in response to food

Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food.


Catalysis of the transfer of an arachidonoyl (systematic name, (5Z,8Z,11Z,14Z)-eicosatetraenoyl) group to a sulfur atom on the cysteine of a protein molecule, in the reaction: in the reaction: (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + L-cysteinyl-[protein] = CoA + S-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-cysteinyl-[protein].


negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process

Any process that stops, prevents or reduces the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.


helvolic acid metabolic process

The chemical reactions and pathways involving helvolic acid.


cyclase activity

Catalysis of a ring closure reaction.


envenomation resulting in negative regulation of sensory perception of pain in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism.


resolvin biosynthetic process

The chemical reactions and pathways resulting in the formation of resolvins, di- or trihydroxy fatty acids derived from omega-3 polyunsaturated fatty acids, specifically icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.


regulation of planar cell polarity pathway involved in outflow tract morphogenesis

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.


positive regulation of hindgut contraction

Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.


Catalysis of the reaction: a 10-formyltetrahydrofolate-4a-carbinolamine = H2O + a 10-formyldihydrofolate.


cell-cell adhesion involved in neural tube closure

The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.


maintenance of vegetative meristem identity

The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


glycolytic fermentation to butanediol

The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.


G2 phase

The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).


The series of molecular signals initiated by interleukin-19 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


visceral peritoneum development

The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.


detection of cAMP

The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.


muscle cell chemotaxis toward tendon cell

The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.


sporocarp development involved in sexual reproduction

The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.


regulation of defecation

Any process that modulates the frequency, rate or extent of defecation.


dGMP biosynthetic process

The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).


termination of RNA polymerase II transcription, exosome-dependent

The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.


regulation by virus of viral protein levels in host cell

Any virus-mediated process that modulates the levels of viral proteins in a cell.


intracellular sequestering of copper ion

The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.


cell-cell signaling involved in pronephros development

Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.


histone H3-K18 acetylation

The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone.


regulation of cellobiose catabolic process

Any process that modulates the frequency, rate or extent of cellobiose catabolic process.


tagaturonate reductase activity

Catalysis of the reaction: D-altronate + NAD+ = D-tagaturonate + H+ + NADH.


Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.


stomatal complex patterning

The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.


n-octane metabolic process

The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.


tRNA folding

The process of assisting in the folding of tRNAs into the correct tertiary structure.


cellular response to stem cell factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.


D-malate dehydrogenase (decarboxylating) activity

Catalysis of the reaction: (R)-malate + NAD+ = CO2 + NADH + pyruvate.


tetralin ring-hydroxylating dioxygenase activity

Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.


modulation by symbiont of host innate immune response

Any process in which a symbiont modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.


intracellular ligand-gated monoatomic ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.


modulation of spore encystment on host

Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.


secondary active oligopeptide transmembrane transporter activity

Enables the transfer of an oligopeptide or oligopeptides from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.


Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP.


deoxyribonucleoside metabolic process

The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


flavonol metabolic process

The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.


nitrobenzene catabolic process

The chemical reactions and pathways resulting in the breakdown of nitrobenzene.


organometal metabolic process

The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.


N-succinyltransferase activity

Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.


hypochlorous acid catabolic process

The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.


tRNA exon ligation

An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed.


pronephric distal tubule development

The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.


Catalysis of the reaction: NAD + D-glucopyranose 6-phosphate = NADH + H+ + 3-dehydro-D-glucose 6-phosphate.


Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+.


steviolbioside glucosyltransferase activity (rebaudioside B forming)

Catalysis of the reaction: steviolbioside + UDP-alpha-D-glucose = rebaudioside B + UDP + H+.


response to anticonvulsant

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.


Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.


1,2-rhamnosyltransferase activity

Catalysis of the reaction: isoorientin + an L-rhamonsylated rhamnosyl acceptor = isoorientin 2'-O-rhamnoside + a non rhamnosylated rhamnosyl acceptor.


beta-ribofuranosylaminobenzene 5'-phosphate synthase activity

Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate.


ecdysone-mediated polytene chromosome puffing

The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.


cell morphogenesis involved in semicircular canal fusion

The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.


viral scaffold assembly and maintenance

The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.


Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD+ = 2-oxopropyl-coenzyme M + H+ + NADH.


primary amino compound catabolic process

The chemical reactions and pathways resulting in the breakdown of primary amino compound.


zygospore formation

The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.


betaine aldehyde catabolic process

The chemical reactions and pathways resulting in the breakdown of betaine aldehyde.


homogentisate metabolic process

The chemical reactions and pathways involving homogentisate.


gated channel activity

Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.


motogenic signaling involved in interneuron migration from the subpallium to the cortex

The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex.


Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.


positive regulation of ectoderm development

Any process that activates or increases the frequency, rate or extent of ectoderm development.


response to clozapine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.


contractile vacuole tethering involved in discharge

The initial, indirect interaction between a contractile vacuole membrane and a site of discharge in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion.


L-seryl-tRNA(Sec) selenium transferase activity

Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.


cardiac neuron development

The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.


(R)-pantolactone dehydrogenase (flavin) activity

Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2).


pseudopodium retraction

The myosin-based contraction and retraction of a pseudopodium.


ferricrocin metabolic process

The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.


regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

Any process that modulates the frequency, rate or extent of an adenylate cyclase-activating adrenergic receptor signaling pathway involved in some heart process.


chloroplast protein-transporting ATPase activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.


chloroplast mRNA processing

Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.


renal system process involved in regulation of systemic arterial blood pressure

Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.


regulation of antigen processing and presentation of peptide antigen

Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.


isopenicillin-N epimerase activity

Catalysis of the reaction: isopenicillin N = penicillin N.


protein myristoylation

The covalent attachment of a myristoyl group to a protein.


cyanidin 3-O-glucoside 6''-O-malonyltransferase activity

Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A.


optical nerve axon regeneration

The regrowth of axons of the optical nerve following their loss or damage.


tight junction disassembly

The disaggregation of an tight junction into its constituent components.


organelle inheritance

The partitioning of organelles between daughter cells at cell division.


positive regulation of border follicle cell delamination

Any process that increases the frequency, rate or extent of border cell delamination.


(1->3)-beta-D-glucan immune receptor activity

Combining with (1->3)-beta-D-glucans to initiate an innate immune response.


(S)-reticuline biosynthetic process

The chemical reactions and pathways resulting in the formation of (S)-reticuline.


di-trans, poly-cis-undecaprenol kinase activity

Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.


positive regulation of innate immunity memory response

Any process that activates or increases the frequency, rate or extent of innate immunity memory response.


regulation of response to salt stress

Any process that modulates the frequency, rate or extent of response to salt stress.


monoterpene catabolic process

The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.


Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.


regulation of catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.


regulation of toll-like receptor 12 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


response to manganese starvation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese.


Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol.


specification of pronephric distal tubule identity

The process in which the distal tubule of the pronephric nephron acquires its identity.


Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.


positive regulation of brown fat cell proliferation

Any process that activates or increases the rate or extent of brown fat cell proliferation.


cerebellar Golgi cell differentiation

The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


gamma-tubulin complex binding

Binding to a gamma-tubulin complex.


DNA-binding transcription repressor activity, RNA polymerase III-specific

A DNA-binding transcription factor activity that represses or decreases the transcription of specific genes sets transcribed by RNA polymerase III.


beta-glucoside metabolic process

The chemical reactions and pathways involving beta-glucoside.


negative regulation of pharyngeal pumping

Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping.


guanosine biosynthetic process

The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution.


response to camptothecin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.


phloem development

The formation of the principal food-conducting tissue of a vascular plant.


cardiac left atrium morphogenesis

The process in which the left cardiac atrium is generated and organized.


GTPase-dependent fusogenic activity

A GTPase activity that mediates the joining two lipid bilayers to form a single membrane.


proline binding

Binding to proline.


negative regulation of glucomannan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process.


fungal-type cell wall chitin biosynthetic process

The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.


DNA alkylation

The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.


reactive nitrogen species metabolic process

The chemical reactions and pathways involving a reactive nitrogen species.


Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.


laminaribiose phosphorylase activity

Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.


pentose catabolic process to ethanol

The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol.


long-term strengthening of neuromuscular junction

Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.


inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors

Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.


nucleoside-specific channel forming porin activity

Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.


regulation of inflorescence meristem growth

Any process involved in maintaining the size and shape of an inflorescence meristem.


negative regulation of cardiac muscle fiber development

Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.


cellular response to plumbagin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.


maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)

Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.


maintenance of floral organ identity

The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


backward locomotion

Posterior movement of an organism, e.g. following the direction of the tail of an animal.


elaioplast organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored.


anterior region determination

Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.


sorbitol metabolic process

The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.


phenylpropanoid metabolic process

The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.


cytoophidium organization

A process which results in the assembly, arrangement of constituent parts, or disassembly of a cytoophidium. Cytoophidia are mesoscale, intracellular, filamentous structures that contain metabolic enzymes.


structural constituent of cuticle

The action of a molecule that contributes to the structural integrity of a cuticle.


single-species biofilm formation on inanimate substrate

A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.


response to lapatinib

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.


chloral hydrate dehydrogenase activity

Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.


maintenance of right sidedness

The organization process that preserves the right sidedness in an organism's body plan or part of an organism with respect to the left and right halves.


chlorobenzene metabolic process

The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.


detection of hormone stimulus

The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal.


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (2S,3R,6S,9S)-(-)-protoillud-7-ene.


Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.


trypanothione metabolic process

The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.


positive regulation of endothelial cell activation

Any process that activates or increases the frequency, rate or extent of endothelial cell activation.


fumiquinazoline C biosynthetic process

The chemical reactions and pathways resulting in the formation of the indole alkaloid fumiquinazoline C.


disruption by symbiont of host cell envelope

The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.


suppression by virus of host type I interferon-mediated signaling pathway

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


protein-phosphocysteine-glucosamine phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).


iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide

The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.


chemorepulsion involved in precerebellar neuron migration

The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration.


salicylic acid metabolic process

The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.


L-threonine catabolic process to propionate

The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.


cellular response to L-phenylalanine derivative

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.


heptadec-1-ene metabolic process

The chemical reactions and pathways involving heptadec-1-ene.


acetoin catabolic process

The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone.


CDP metabolic process

The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.


response to miconazole

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.


O-glycan processing, core 5

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.


malonate(1-) transmembrane transporter activity

Enables the transfer of malonate(1-) from one side of a membrane to the other.


carbohydrate derivative biosynthetic process

The chemical reactions and pathways resulting in the formation of carbohydrate derivative.


Wnt signaling pathway involved in heart development

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.


tyrosine ammonia-lyase activity

Catalysis of the reaction: L-tyrosine = NH4 + trans-4-coumarate.