DISC1_HUMAN Disrupted in schizophrenia 1 protein (sprot)

A disrupted in schizophrenia 1 protein that is encoded in the genome of human.


PYY2_HUMAN Putative peptide YY-2 (sprot)


MOST1_HUMAN Protein MOST-1 (sprot)

A protein that is a translation product of the C8orf17 gene in human.


CCL28_HUMAN C-C motif chemokine 28 (sprot)

A C-C motif chemokine 28 that is encoded in the genome of human.


TULP4_HUMAN Tubby-related protein 4 (sprot)

A tubby-related protein 4 that is encoded in the genome of human.


PAPOB_HUMAN Poly(A) polymerase beta (sprot)

A poly(A) polymerase beta that is encoded in the genome of human.


PCDBG_HUMAN Protocadherin beta-16 (sprot)

A protocadherin beta-16 that is encoded in the genome of human.


ABCBA_HUMAN ATP-binding cassette sub-family B member 10, mitochondrial (sprot)

An ATP-binding cassette sub-family B member 10, mitochondrial that is encoded in the genome of human.


mitochondrial unfolded protein response

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.


BAZ1A_HUMAN Bromodomain adjacent to zinc finger domain protein 1A (sprot)

A bromodomain adjacent to zinc finger domain protein 1A that is encoded in the genome of human.


STRN4_HUMAN Striatin-4 (sprot)

A striatin-4 that is encoded in the genome of human.


GTR9_HUMAN Solute carrier family 2, facilitated glucose transporter member 9 (sprot)

A solute carrier family 2, facilitated glucose transporter member 9 that is encoded in the genome of human.


ENAM_HUMAN Enamelin (sprot)

An enamelin that is encoded in the genome of human.


ZN277_HUMAN Zinc finger protein 277 (sprot)

A zinc finger protein 277 that is encoded in the genome of human.


I17RB_HUMAN Interleukin-17 receptor B (sprot)

An interleukin-17 receptor B that is encoded in the genome of human.


LATS2_HUMAN Serine/threonine-protein kinase LATS2 (sprot)

A serine/threonine-protein kinase LATS2 that is encoded in the genome of human.


OLFL3_HUMAN Olfactomedin-like protein 3 (sprot)

An olfactomedin-like protein 3 that is encoded in the genome of human.


ADPPT_HUMAN L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (sprot)

An L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase that is encoded in the genome of human.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.


METL5_HUMAN rRNA N6-adenosine-methyltransferase METTL5 (sprot)

An rRNA N6-adenosine-methyltransferase METTL5 that is encoded in the genome of human.


OSTC_HUMAN Oligosaccharyltransferase complex subunit OSTC (sprot)

An oligosaccharyltransferase complex subunit OSTC that is encoded in the genome of human.


COXM2_HUMAN COX assembly mitochondrial protein 2 homolog (sprot)

A COX assembly mitochondrial protein 2 homolog that is encoded in the genome of human.


SDHF3_HUMAN Succinate dehydrogenase assembly factor 3, mitochondrial (sprot)

A protein ACN9, mitochondrial that is encoded in the genome of human.


STK36_HUMAN Serine/threonine-protein kinase 36 (sprot)

A serine/threonine-protein kinase 36 that is encoded in the genome of human.


PLS4_HUMAN Phospholipid scramblase 4 (sprot)

A phospholipid scramblase 4 that is encoded in the genome of human.


SMCO4_HUMAN Single-pass membrane and coiled-coil domain-containing protein 4 (sprot)

A single-pass membrane and coiled-coil domain-containing protein 4 that is encoded in the genome of human.


CYTL1_HUMAN Cytokine-like protein 1 (sprot)

A cytokine-like protein 1 that is encoded in the genome of human.


TRYG1_HUMAN Tryptase gamma (sprot)

A tryptase gamma that is encoded in the genome of human.


C42S2_HUMAN CDC42 small effector protein 2 (sprot)

A CDC42 small effector protein 2 that is encoded in the genome of human.


RNC_HUMAN Ribonuclease 3 (sprot)

A ribonuclease 3 that is encoded in the genome of human.


UBQL4_HUMAN Ubiquilin-4 (sprot)

A ubiquilin-4 that is encoded in the genome of human.


nuclear proteasome complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A proteasome found in the nucleus of a cell.


INP5E_HUMAN Phosphatidylinositol polyphosphate 5-phosphatase type IV (sprot)

A phosphatidylinositol polyphosphate 5-phosphatase type IV that is encoded in the genome of human.


C42S1_HUMAN CDC42 small effector protein 1 (sprot)

A CDC42 small effector protein 1 that is encoded in the genome of human.


TMPS4_HUMAN Transmembrane protease serine 4 (sprot)

A transmembrane protease serine 4 that is encoded in the genome of human.


negative regulation of growth rate

Any process that reduces the rate of growth of all or part of an organism.


SNX15_HUMAN Sorting nexin-15 (sprot)

A sorting nexin-15 that is encoded in the genome of human.


CNNM1_HUMAN Metal transporter CNNM1 (sprot)

A metal transporter CNNM1 that is encoded in the genome of human.


HEBP1_HUMAN Heme-binding protein 1 (sprot)

A heme-binding protein 1 that is encoded in the genome of human.


RAB6B_HUMAN Ras-related protein Rab-6B (sprot)

A Ras-related protein Rab-6B that is encoded in the genome of human.


ABC3C_HUMAN DNA dC->dU-editing enzyme APOBEC-3C (sprot)

A DNA dC->dU-editing enzyme APOBEC-3C that is encoded in the genome of human.


DUS22_HUMAN Dual specificity protein phosphatase 22 (sprot)

A dual specificity protein phosphatase 22 that is encoded in the genome of human.


negative regulation of non-membrane spanning protein tyrosine kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.


VPS45_HUMAN Vacuolar protein sorting-associated protein 45 (sprot)

A vacuolar protein sorting-associated protein 45 that is encoded in the genome of human.


PNO1_HUMAN RNA-binding protein PNO1 (sprot)

An RNA-binding protein PNO1 that is encoded in the genome of human.


RM17_HUMAN Large ribosomal subunit protein bL17m (sprot)

A 39S ribosomal protein L17, mitochondrial that is encoded in the genome of human.


PHP14_HUMAN 14 kDa phosphohistidine phosphatase (sprot)

A 14 kDa phosphohistidine phosphatase that is encoded in the genome of human.


protein histidine phosphatase activity

Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate.


peptidyl-histidine dephosphorylation

The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.


negative regulation of lyase activity

Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.


negative regulation of ATP citrate synthase activity

Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.


SERC1_HUMAN Serine incorporator 1 (sprot)

A serine incorporator 1 that is encoded in the genome of human.


KISHB_HUMAN Protein kish-B (sprot)

A protein kish-B that is encoded in the genome of human.


SOSSC_HUMAN SOSS complex subunit C (sprot)

A SOSS complex subunit C that is encoded in the genome of human.


RHG35_HUMAN Rho GTPase-activating protein 35 (sprot)

A Rho GTPase-activating protein 35 that is encoded in the genome of human.


F1142_HUMAN Protein FAM114A2 (sprot)

A protein FAM114A2 that is encoded in the genome of human.


PLS3_HUMAN Phospholipid scramblase 3 (sprot)

A phospholipid scramblase 3 that is encoded in the genome of human.


regulation of release of cytochrome c from mitochondria

Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.


PLS2_HUMAN Phospholipid scramblase 2 (sprot)

A phospholipid scramblase 2 that is encoded in the genome of human.


PLCD_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase delta (sprot)

A 1-acyl-sn-glycerol-3-phosphate acyltransferase delta that is encoded in the genome of human.


PLCC_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (sprot)

A 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma that is encoded in the genome of human.


HELLS_HUMAN Lymphoid-specific helicase (sprot)

A lymphoid-specific helicase that is encoded in the genome of human.


C1GLT_HUMAN Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (sprot)

A glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 that is encoded in the genome of human.


Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan.


LTBP3_HUMAN Latent-transforming growth factor beta-binding protein 3 (sprot)

A latent-transforming growth factor beta-binding protein 3 that is encoded in the genome of human.


transforming growth factor beta activation

The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms.


GLRX2_HUMAN Glutaredoxin-2, mitochondrial (sprot)

A glutaredoxin-2, mitochondrial that is encoded in the genome of human.


arsenate reductase (glutaredoxin) activity

Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.


cellular response to superoxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.


RASF1_HUMAN Ras association domain-containing protein 1 (sprot)

A Ras association domain-containing protein 1 that is encoded in the genome of human.


SPNXB_HUMAN Sperm protein associated with the nucleus on the X chromosome B1 (sprot)

A sperm protein associated with the nucleus on the X chromosome B1 that is encoded in the genome of human.


SPNXA_HUMAN Sperm protein associated with the nucleus on the X chromosome A (sprot)

A sperm protein associated with the nucleus on the X chromosome A that is encoded in the genome of human.


RGS18_HUMAN Regulator of G-protein signaling 18 (sprot)

A regulator of G-protein signaling 18 that is encoded in the genome of human.


ZHANG_HUMAN CREB/ATF bZIP transcription factor (sprot)

A CREB/ATF bZIP transcription factor that is encoded in the genome of human.


RED2_HUMAN Double-stranded RNA-specific editase B2 (sprot)

A double-stranded RNA-specific editase B2 that is encoded in the genome of human.


KCNH7_HUMAN Potassium voltage-gated channel subfamily H member 7 (sprot)

A voltage-gated potassium channel KCNH7 that is encoded in the genome of human.


TOPRS_HUMAN E3 ubiquitin-protein ligase Topors (sprot)

An E3 ubiquitin-protein ligase Topors that is encoded in the genome of human.


KCIP2_HUMAN Kv channel-interacting protein 2 (sprot)

A Kv channel-interacting protein 2 that is encoded in the genome of human.


A-type (transient outward) potassium channel activity

Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.


Kv4.2-KChIP2 channel complex

A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.


THSD1_HUMAN Thrombospondin type-1 domain-containing protein 1 (sprot)

A thrombospondin type-1 domain-containing protein 1 that is encoded in the genome of human.


RPRM_HUMAN Protein reprimo (sprot)

A protein reprimo that is encoded in the genome of human.


GP173_HUMAN Probable G-protein coupled receptor 173 (sprot)

A probable G-protein coupled receptor 173 that is encoded in the genome of human.


GPR27_HUMAN Probable G-protein coupled receptor 27 (sprot)

A probable G-protein coupled receptor 27 that is encoded in the genome of human.


TNR19_HUMAN Tumor necrosis factor receptor superfamily member 19 (sprot)

A tumor necrosis factor receptor superfamily member 19 that is encoded in the genome of human.


TOM22_HUMAN Mitochondrial import receptor subunit TOM22 homolog (sprot)

A mitochondrial import receptor subunit TOM22 that is encoded in the genome of human.


GKN1_HUMAN Gastrokine-1 (sprot)

A gastrokine-1 that is encoded in the genome of human.


MBIP1_HUMAN MAP3K12-binding inhibitory protein 1 (sprot)

A MAP3K12-binding inhibitory protein 1 that is encoded in the genome of human.


CLTR2_HUMAN Cysteinyl leukotriene receptor 2 (sprot)

A cysteinyl leukotriene receptor 2 that is encoded in the genome of human.


AAA1_HUMAN Asc-type amino acid transporter 1 (sprot)

An asc-type amino acid transporter 1 that is encoded in the genome of human.


positive regulation of synaptic transmission, glycinergic

Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.


CHST7_HUMAN Carbohydrate sulfotransferase 7 (sprot)

A carbohydrate sulfotransferase 7 that is encoded in the genome of human.


CAH10_HUMAN Carbonic anhydrase-related protein 10 (sprot)

A carbonic anhydrase-related protein 10 that is encoded in the genome of human.


LANC2_HUMAN LanC-like protein 2 (sprot)

A LanC-like protein 2 that is encoded in the genome of human.


positive regulation of abscisic acid-activated signaling pathway

Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.


KIF15_HUMAN Kinesin-like protein KIF15 (sprot)

A kinesin-like protein KIF15 that is encoded in the genome of human.


RAD18_HUMAN E3 ubiquitin-protein ligase RAD18 (sprot)

An E3 ubiquitin-protein ligase RAD18 that is encoded in the genome of human.


TM7S3_HUMAN Transmembrane 7 superfamily member 3 (sprot)

A transmembrane 7 superfamily member 3 that is encoded in the genome of human.


SEM3G_HUMAN Semaphorin-3G (sprot)

A semaphorin-3G that is encoded in the genome of human.


S22AB_HUMAN Solute carrier family 22 member 11 (sprot)

A solute carrier family 22 member 11 that is encoded in the genome of human.


FGF21_HUMAN Fibroblast growth factor 21 (sprot)

A fibroblast growth factor 21 that is encoded in the genome of human.


KCND1_HUMAN Potassium voltage-gated channel subfamily D member 1 (sprot)

A voltage-gated potassium channel KCND1 that is encoded in the genome of human.


CNBP1_HUMAN Beta-catenin-interacting protein 1 (sprot)

A beta-catenin-interacting protein 1 that is encoded in the genome of human.


KRT84_HUMAN Keratin, type II cuticular Hb4 (sprot)

A keratin, type II cuticular Hb4 that is encoded in the genome of human.


KRT82_HUMAN Keratin, type II cuticular Hb2 (sprot)

A keratin, type II cuticular Hb2 that is encoded in the genome of human.


HOME2_HUMAN Homer protein homolog 2 (sprot)

A homer protein homolog 2 that is encoded in the genome of human.


SALL1_HUMAN Sal-like protein 1 (sprot)

A Sal-like protein 1 that is encoded in the genome of human.


inductive cell-cell signaling

Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.


HOME3_HUMAN Homer protein homolog 3 (sprot)

A homer protein homolog 3 that is encoded in the genome of human.


SIA7A_HUMAN Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 (sprot)

An alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 that is encoded in the genome of human.


ZN275_HUMAN Zinc finger protein 275 (sprot)

A zinc finger protein 275 that is encoded in the genome of human.


S6A13_HUMAN Sodium- and chloride-dependent GABA transporter 2 (sprot)

A sodium- and chloride-dependent GABA transporter 2 that is encoded in the genome of human.


RL3R1_HUMAN Relaxin-3 receptor 1 (sprot)

A relaxin-3 receptor 1 that is encoded in the genome of human.


SYFB_HUMAN Phenylalanine--tRNA ligase beta subunit (sprot)

A eukaryotic-type phenylalanine--tRNA ligase beta subunit that is encoded in the genome of human.


phenylalanine-tRNA ligase complex

An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).


CISH_HUMAN Cytokine-inducible SH2-containing protein (sprot)

A cytokine-inducible SH2-containing protein that is encoded in the genome of human.


SYIM_HUMAN Isoleucine--tRNA ligase, mitochondrial (sprot)

An isoleucine--tRNA ligase, mitochondrial that is encoded in the genome of human.


FIRRM_HUMAN FIGNL1-interacting regulator of recombination and mitosis (sprot)

An uncharacterized protein C1orf112 that is encoded in the genome of human.


SLX9_HUMAN Ribosome biogenesis protein SLX9 homolog (sprot)

A ribosome biogenesis protein SLX9 homolog that is encoded in the genome of human.


IGSF5_HUMAN Immunoglobulin superfamily member 5 (sprot)

An immunoglobulin superfamily member 5 that is encoded in the genome of human.


BRWD1_HUMAN Bromodomain and WD repeat-containing protein 1 (sprot)

A bromodomain and WD repeat-containing protein 1 that is encoded in the genome of human.


SAMN1_HUMAN SAM domain-containing protein SAMSN-1 (sprot)

A SAM domain-containing protein SAMSN-1 that is encoded in the genome of human.


Z355P_HUMAN Putative zinc finger protein 355P (sprot)


KLC4_HUMAN Kinesin light chain 4 (sprot)

A kinesin light chain 4 that is encoded in the genome of human.


CS012_HUMAN Protein C19orf12 (sprot)

A protein C19orf12 that is encoded in the genome of human.


SNTG1_HUMAN Gamma-1-syntrophin (sprot)

A gamma-1-syntrophin that is encoded in the genome of human.


CENPM_HUMAN Centromere protein M (sprot)

A centromere protein M that is encoded in the genome of human.


PLPL3_HUMAN 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (sprot)

A 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 that is encoded in the genome of human.


triglyceride acyl-chain remodeling

Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.


TREX1_HUMAN Three-prime repair exonuclease 1 (sprot)

A three-prime repair exonuclease 1 that is encoded in the genome of human.


adenyl deoxyribonucleotide binding

Binding to an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.


immune response in brain or nervous system

An immune response taking place in the brain or nervous system.


immune complex formation

The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.


DIAP3_HUMAN Protein diaphanous homolog 3 (sprot)

A protein diaphanous homolog 3 that is encoded in the genome of human.


protein-containing complex remodeling

The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.


stereocilia tip-link density

An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane.


NRBP2_HUMAN Nuclear receptor-binding protein 2 (sprot)

A nuclear receptor-binding protein 2 that is encoded in the genome of human.


BMP2K_HUMAN BMP-2-inducible protein kinase (sprot)

A BMP-2-inducible protein kinase that is encoded in the genome of human.


STAR5_HUMAN StAR-related lipid transfer protein 5 (sprot)

A StAR-related lipid transfer protein 5 that is encoded in the genome of human.


EMIL3_HUMAN EMILIN-3 (sprot)

An EMILIN-3 that is encoded in the genome of human.


ATG3_HUMAN Ubiquitin-like-conjugating enzyme ATG3 (sprot)

A ubiquitin-like-conjugating enzyme ATG3 that is encoded in the genome of human.


Atg8-family conjugating enzyme activity

Isoenergetic transfer of an Atg8 family modifer from one protein to a phosphatidylethanolamine or  phosphatidylserine on a membrane, via the reaction X-Atg8 + Y = Y-Atg8 + X.


TEN2_HUMAN Teneurin-2 (sprot)

A teneurin-2 that is encoded in the genome of human.


LRC4B_HUMAN Leucine-rich repeat-containing protein 4B (sprot)

A leucine-rich repeat-containing protein 4B that is encoded in the genome of human.


PKDRE_HUMAN Polycystin family receptor for egg jelly (sprot)

A polycystin family receptor for egg jelly that is encoded in the genome of human.


SIR3_HUMAN NAD-dependent protein deacetylase sirtuin-3, mitochondrial (sprot)

An NAD-dependent protein deacetylase sirtuin-3, mitochondrial that is encoded in the genome of human.


positive regulation of catalase activity

Any process that activates or increases the frequency, rate or extent of catalase activity.


AT8A2_HUMAN Phospholipid-transporting ATPase IB (sprot)

A phospholipid-transporting ATPase IB that is encoded in the genome of human.


involuntary skeletal muscle contraction

A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.


PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B (sprot)

A sister chromatid cohesion protein PDS5 homolog B that is encoded in the genome of human.


INKA2_HUMAN PAK4-inhibitor INKA2 (sprot)

A PAK4-inhibitor INKA2 that is encoded in the genome of human.


SMC4_HUMAN Structural maintenance of chromosomes protein 4 (sprot)

A structural maintenance of chromosomes protein 4 that is encoded in the genome of human.


MA2C1_HUMAN Alpha-mannosidase 2C1 (sprot)

An alpha-mannosidase 2C1 that is encoded in the genome of human.


SAC1_HUMAN Phosphatidylinositol-3-phosphatase SAC1 (sprot)

A phosphatidylinositol-3-phosphatase SAC1 that is encoded in the genome of human.


DEPP1_HUMAN Protein DEPP1 (sprot)

A protein DEPP1 that is encoded in the genome of human.


OLA1_HUMAN Obg-like ATPase 1 (sprot)

An obg-like ATPase 1 that is encoded in the genome of human.


CUTC_HUMAN Copper homeostasis protein cutC homolog (sprot)

A copper homeostasis protein cutC that is encoded in the genome of human.


S35D1_HUMAN Nucleotide sugar transporter SLC35D1 (sprot)

A UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter that is encoded in the genome of human.


UDP-glucuronic acid transmembrane transporter activity

Enables the transfer of a UDP-glucuronic acid from one side of a membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.


SEM4G_HUMAN Semaphorin-4G (sprot)

A semaphorin-4G that is encoded in the genome of human.


CXB4_HUMAN Gap junction beta-4 protein (sprot)

A gap junction beta-4 protein that is encoded in the genome of human.


CTSRZ_HUMAN Cation channel sperm-associated auxiliary subunit zeta (sprot)

A cation channel sperm-associated protein subunit zeta that is encoded in the genome of human.


CBLN4_HUMAN Cerebellin-4 (sprot)

A cerebellin-4 that is encoded in the genome of human.


ZF64B_HUMAN Zinc finger protein 64 (sprot)

A zinc finger protein 64 that is encoded in the genome of human.


megasporocyte nucleus

The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents.


ECHD1_HUMAN Ethylmalonyl-CoA decarboxylase (sprot)

An ethylmalonyl-CoA decarboxylase that is encoded in the genome of human.


methyl/ethyl malonyl-CoA decarboxylase activity

Catalysis of the reaction: (S)-methylmalonyl-CoA + H+ = CO2 + propanoyl-CoA or (2S)-ethylmalonyl-CoA + H+ = butanoyl-CoA + CO2.


RN146_HUMAN E3 ubiquitin-protein ligase RNF146 (sprot)

An E3 ubiquitin-protein ligase RNF146 that is encoded in the genome of human.


F217B_HUMAN Protein FAM217B (sprot)

A protein FAM217B that is encoded in the genome of human.


RBM12_HUMAN RNA-binding protein 12 (sprot)

An RNA-binding protein 12 that is encoded in the genome of human.


ANKE1_HUMAN Ankyrin repeat and EF-hand domain-containing protein 1 (sprot)

An ankyrin repeat and EF-hand domain-containing protein 1 that is encoded in the genome of human.


TB22B_HUMAN TBC1 domain family member 22B (sprot)

A TBC1 domain family member 22B that is encoded in the genome of human.


MDN1_HUMAN Midasin (sprot)

A midasin that is encoded in the genome of human.


LYRM2_HUMAN LYR motif-containing protein 2 (sprot)

A LYR motif-containing protein 2 that is encoded in the genome of human.


FX4L1_HUMAN Forkhead box protein D4-like 1 (sprot)

A forkhead box protein D4-like 1 that is encoded in the genome of human.


GINM1_HUMAN Glycoprotein integral membrane protein 1 (sprot)

A glycoprotein integral membrane protein 1 that is encoded in the genome of human.


ZFP57_HUMAN Zinc finger protein 57 homolog (sprot)

A zinc finger protein 57 homolog that is encoded in the genome of human.


ZBT40_HUMAN Zinc finger and BTB domain-containing protein 40 (sprot)

A zinc finger and BTB domain-containing protein 40 that is encoded in the genome of human.


ACS2L_HUMAN Acetyl-coenzyme A synthetase 2-like, mitochondrial (sprot)

An acetyl-coenzyme A synthetase 2-like, mitochondrial that is encoded in the genome of human.


CT141_HUMAN Uncharacterized protein C20orf141 (sprot)

A protein that is a translation product of the C20orf141 gene in human.


SRTD4_HUMAN SERTA domain-containing protein 4 (sprot)

A SERTA domain-containing protein 4 that is encoded in the genome of human.


ZCHC3_HUMAN Zinc finger CCHC domain-containing protein 3 (sprot)

A zinc finger CCHC domain-containing protein 3 that is encoded in the genome of human.


PIGV_HUMAN GPI mannosyltransferase 2 (sprot)

A GPI mannosyltransferase 2 that is encoded in the genome of human.


alpha-1,6-mannosyltransferase activity

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.


ZDH18_HUMAN Palmitoyltransferase ZDHHC18 (sprot)

A palmitoyltransferase ZDHHC18 that is encoded in the genome of human.


CCM2L_HUMAN Cerebral cavernous malformations 2 protein-like (sprot)

A cerebral cavernous malformations 2 protein-like that is encoded in the genome of human.


PDRG1_HUMAN p53 and DNA damage-regulated protein 1 (sprot)

A p53 and DNA damage-regulated protein 1 that is encoded in the genome of human.


TM14B_HUMAN Transmembrane protein 14B (sprot)

A transmembrane protein 14B that is encoded in the genome of human.


DECR2_HUMAN Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (sprot)

A peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] that is encoded in the genome of human.


ABHDA_HUMAN Palmitoyl-protein thioesterase ABHD10, mitochondrial (sprot)

A palmitoyl-protein thioesterase ABHD10, mitochondrial that is encoded in the genome of human.


mycophenolic acid acyl-glucuronide esterase activity

Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate.


glucuronoside catabolic process

The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.


T11L1_HUMAN T-complex protein 11-like protein 1 (sprot)

A T-complex protein 11-like protein 1 that is encoded in the genome of human.


PLCX1_HUMAN PI-PLC X domain-containing protein 1 (sprot)

A PI-PLC X domain-containing protein 1 that is encoded in the genome of human.


MBNL3_HUMAN Muscleblind-like protein 3 (sprot)

A muscleblind-like protein 3 that is encoded in the genome of human.


STAU2_HUMAN Double-stranded RNA-binding protein Staufen homolog 2 (sprot)

A double-stranded RNA-binding protein Staufen homolog 2 that is encoded in the genome of human.


SHFL_HUMAN Shiftless antiviral inhibitor of ribosomal frameshifting protein (sprot)

A shiftless antiviral inhibitor of ribosomal frameshifting protein that is encoded in the genome of human.


viral translational frameshifting

A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins.


negative regulation of translational frameshifting

Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting.


DDX28_HUMAN Probable ATP-dependent RNA helicase DDX28 (sprot)

A probable ATP-dependent RNA helicase DDX28 that is encoded in the genome of human.


S39A9_HUMAN Zinc transporter ZIP9 (sprot)

A zinc transporter ZIP9 that is encoded in the genome of human.


zinc efflux transmembrane transporter activity

Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.


regulation of cellular response to testosterone stimulus

Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.


T106B_HUMAN Transmembrane protein 106B (sprot)

A transmembrane protein 106B that is encoded in the genome of human.


LMBD1_HUMAN Lysosomal cobalamin transport escort protein LMBD1 (sprot)

A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of human.


ACER3_HUMAN Alkaline ceramidase 3 (sprot)

An alkaline ceramidase 3 that is encoded in the genome of human.


phytoceramidase activity

Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.


phytosphingosine biosynthetic process

The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.


BL1S4_HUMAN Biogenesis of lysosome-related organelles complex 1 subunit 4 (sprot)

A biogenesis of lysosome-related organelles complex 1 subunit 4 that is encoded in the genome of human.


TRM13_HUMAN tRNA:m(4)X modification enzyme TRM13 homolog (sprot)

A tRNA guanosine-2'-O-methyltransferase TRM13 that is encoded in the genome of human.


tRNA 2'-O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.


LIN7C_HUMAN Protein lin-7 homolog C (sprot)

A protein lin-7 homolog C that is encoded in the genome of human.


PLCE_HUMAN 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (sprot)

A 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon that is encoded in the genome of human.


acylglycerol metabolic process

The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.


TXLNG_HUMAN Gamma-taxilin (sprot)

A gamma-taxilin that is encoded in the genome of human.


SPS2L_HUMAN SPATS2-like protein (sprot)

A SPATS2-like protein that is encoded in the genome of human.


UFSP2_HUMAN Ufm1-specific protease 2 (sprot)

A Ufm1-specific protease 2 that is encoded in the genome of human.


deUFMylase activity

A thiol-dependent isopeptidase activity that cleaves UFM1 from a target protein to which it is conjugated.


ABCF3_HUMAN ATP-binding cassette sub-family F member 3 (sprot)

An ATP-binding cassette sub-family F member 3 that is encoded in the genome of human.


CYRIB_HUMAN CYFIP-related Rac1 interactor B (sprot)

A CYFIP-related Rac1 interactor B that is encoded in the genome of human.


TM74B_HUMAN Transmembrane protein 74B (sprot)

A transmembrane protein 74B that is encoded in the genome of human.


AP5S1_HUMAN AP-5 complex subunit sigma-1 (sprot)

An AP-5 complex subunit sigma-1 that is encoded in the genome of human.


MITOS_HUMAN Mitochondrial potassium channel ATP-binding subunit (sprot)

A mitochondrial potassium channel ATP-binding subunit that is encoded in the genome of human.


OTULL_HUMAN Inactive ubiquitin thioesterase OTULINL (sprot)

An inactive ubiquitin thioesterase OTULINL that is encoded in the genome of human.


DD19A_HUMAN ATP-dependent RNA helicase DDX19A (sprot)

An ATP-dependent RNA helicase DDX19A that is encoded in the genome of human.


SPTC3_HUMAN Serine palmitoyltransferase 3 (sprot)

A serine palmitoyltransferase 3 that is encoded in the genome of human.


sphingoid biosynthetic process

The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.


GIMA4_HUMAN GTPase IMAP family member 4 (sprot)

A GTPase IMAP family member 4 that is encoded in the genome of human.


TYDP1_HUMAN Tyrosyl-DNA phosphodiesterase 1 (sprot)

A tyrosyl-DNA phosphodiesterase 1 that is encoded in the genome of human.


Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.


POTE1_HUMAN Protection of telomeres protein 1 (sprot)

A protection of telomeres protein 1 that is encoded in the genome of human.


G-rich single-stranded DNA binding

Binding to G-rich, single-stranded DNA.


positive regulation of DNA strand elongation

Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.


regulation of DNA helicase activity

Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity.


TBC23_HUMAN TBC1 domain family member 23 (sprot)

A TBC1 domain family member 23 that is encoded in the genome of human.


ACOXL_HUMAN Acyl-coenzyme A oxidase-like protein (sprot)

An acyl-coenzyme A oxidase-like protein that is encoded in the genome of human.


DCA13_HUMAN DDB1- and CUL4-associated factor 13 (sprot)

A DDB1- and CUL4-associated factor 13 that is encoded in the genome of human.


TM140_HUMAN Transmembrane protein 140 (sprot)

A transmembrane protein 140 that is encoded in the genome of human.


SAST_HUMAN S-acyl fatty acid synthase thioesterase, medium chain (sprot)

An S-acyl fatty acid synthase thioesterase, medium chain that is encoded in the genome of human.


Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate.


Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein].


TM100_HUMAN Transmembrane protein 100 (sprot)

A transmembrane protein 100 that is encoded in the genome of human.


IMP3_HUMAN U3 small nucleolar ribonucleoprotein protein IMP3 (sprot)

A U3 small nucleolar ribonucleoprotein protein IMP3 that is encoded in the genome of human.


NUD15_HUMAN Nucleotide triphosphate diphosphatase NUDT15 (sprot)

A nucleotide triphosphate diphosphatase that is encoded in the genome of human.


dGTP catabolic process

The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.


nucleoside phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.


PRR34_HUMAN Proline-rich protein 34 (sprot)

A protein that is a translation product of the PRR34 gene in human.


MRGBP_HUMAN MRG/MORF4L-binding protein (sprot)

An MRG/MORF4L-binding protein that is encoded in the genome of human.


RN19A_HUMAN E3 ubiquitin-protein ligase RNF19A (sprot)

An E3 ubiquitin-protein ligase RNF19A that is encoded in the genome of human.


TM39A_HUMAN Transmembrane protein 39A (sprot)

A transmembrane protein 39A that is encoded in the genome of human.


TYW1_HUMAN S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (sprot)

An S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 that is encoded in the genome of human.


EXOC1_HUMAN Exocyst complex component 1 (sprot)

An exocyst complex component 1 that is encoded in the genome of human.


ZN701_HUMAN Zinc finger protein 701 (sprot)

A zinc finger protein 701 that is encoded in the genome of human.


PCMD2_HUMAN Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 (sprot)

A protein-L-isoaspartate O-methyltransferase domain-containing protein 2 that is encoded in the genome of human.


INT9_HUMAN Integrator complex subunit 9 (sprot)

An integrator complex subunit 9 that is encoded in the genome of human.


NFIP2_HUMAN NEDD4 family-interacting protein 2 (sprot)

A NEDD4 family-interacting protein 2 that is encoded in the genome of human.


CC50A_HUMAN Cell cycle control protein 50A (sprot)

A cell cycle control protein 50A that is encoded in the genome of human.


UQCC1_HUMAN Ubiquinol-cytochrome-c reductase complex assembly factor 1 (sprot)

A ubiquinol-cytochrome-c reductase complex assembly factor 1 that is encoded in the genome of human.


SEP11_HUMAN Septin-11 (sprot)

A septin-11 that is encoded in the genome of human.


postsynaptic specialization of symmetric synapse

A network of proteins within and adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.


T184C_HUMAN Transmembrane protein 184C (sprot)

A transmembrane protein 184C that is encoded in the genome of human.


S38A7_HUMAN Sodium-coupled neutral amino acid transporter 7 (sprot)

A sodium-coupled neutral amino acid transporter 7 that is encoded in the genome of human.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-asparagine(out) + Na+(out) = L-asparagine(in) + Na+(in).


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-glutamine(out) + Na+(out) = L-glutamine(in) + Na+(in).


MED17_HUMAN Mediator of RNA polymerase II transcription subunit 17 (sprot)

A mediator of RNA polymerase II transcription subunit 17 that is encoded in the genome of human.


SETD4_HUMAN SET domain-containing protein 4 (sprot)

A SET domain-containing protein 4 that is encoded in the genome of human.


regulation of cell proliferation in bone marrow

A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow.


PARVA_HUMAN Alpha-parvin (sprot)

An alpha-parvin that is encoded in the genome of human.


CCD87_HUMAN Coiled-coil domain-containing protein 87 (sprot)

A coiled-coil domain-containing protein 87 that is encoded in the genome of human.


UBP40_HUMAN Ubiquitin carboxyl-terminal hydrolase 40 (sprot)

A ubiquitin carboxyl-terminal hydrolase 40 that is encoded in the genome of human.


PANK4_HUMAN 4'-phosphopantetheine phosphatase (sprot)

A 4'-phosphopantetheine phosphatase that is encoded in the genome of human.


FBX28_HUMAN F-box only protein 28 (sprot)

An F-box only protein 28 that is encoded in the genome of human.


EKI2_HUMAN Ethanolamine kinase 2 (sprot)

An ethanolamine kinase 2 that is encoded in the genome of human.


TBC13_HUMAN TBC1 domain family member 13 (sprot)

A TBC1 domain family member 13 that is encoded in the genome of human.


EXD2_HUMAN Exonuclease 3'-5' domain-containing protein 2 (sprot)

An exonuclease 3'-5' domain-containing protein 2 that is encoded in the genome of human.


DJC11_HUMAN DnaJ homolog subfamily C member 11 (sprot)

A DnaJ homolog subfamily C member 11 that is encoded in the genome of human.


INT7_HUMAN Integrator complex subunit 7 (sprot)

An integrator complex subunit 7 that is encoded in the genome of human.


TMLH_HUMAN Trimethyllysine dioxygenase, mitochondrial (sprot)

A trimethyllysine dioxygenase, mitochondrial that is encoded in the genome of human.


trimethyllysine dioxygenase activity

Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate.


FANCI_HUMAN Fanconi anemia group I protein (sprot)

A Fanconi anemia group I protein that is encoded in the genome of human.


ATD3A_HUMAN ATPase family AAA domain-containing protein 3A (sprot)

An ATPase family AAA domain-containing protein 3A that is encoded in the genome of human.


ARL8B_HUMAN ADP-ribosylation factor-like protein 8B (sprot)

An ADP-ribosylation factor-like protein 8B that is encoded in the genome of human.


antigen processing and presentation of polysaccharide antigen via MHC class II

The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.


antigen processing and presentation following phagocytosis

Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.


viral exocytosis

The exit of a fully formed virion particles from the host cell by exocytosis via a host vesicle.


FGOP2_HUMAN FGFR1 oncogene partner 2 (sprot)

An FGFR1 oncogene partner 2 that is encoded in the genome of human.


F86C1_HUMAN Putative protein FAM86C1P (sprot)

A putative protein FAM86C1P that is encoded in the genome of human.


CC198_HUMAN Uncharacterized protein CCDC198 (sprot)

An uncharacterized protein CCDC198 that is encoded in the genome of human.


EVA1B_HUMAN Protein eva-1 homolog B (sprot)

A protein eva-1 homolog B that is encoded in the genome of human.


ANM7_HUMAN Protein arginine N-methyltransferase 7 (sprot)

A protein arginine N-methyltransferase 7 that is encoded in the genome of human.


DJC17_HUMAN DnaJ homolog subfamily C member 17 (sprot)

A DnaJ homolog subfamily C member 17 that is encoded in the genome of human.


INT13_HUMAN Integrator complex subunit 13 (sprot)

An integrator complex subunit 13 that is encoded in the genome of human.


RIC8B_HUMAN Synembryn-B (sprot)

A synembryn-B that is encoded in the genome of human.


GNL3L_HUMAN Guanine nucleotide-binding protein-like 3-like protein (sprot)

A guanine nucleotide-binding protein-like 3-like protein that is encoded in the genome of human.


DDX18_HUMAN ATP-dependent RNA helicase DDX18 (sprot)

An ATP-dependent RNA helicase DDX18 that is encoded in the genome of human.


ASF1B_HUMAN Histone chaperone ASF1B (sprot)

A histone chaperone ASF1B that is encoded in the genome of human.


DZAN1_HUMAN Double zinc ribbon and ankyrin repeat-containing protein 1 (sprot)

A double zinc ribbon and ankyrin repeat-containing protein 1 that is encoded in the genome of human.


FAIM1_HUMAN Fas apoptotic inhibitory molecule 1 (sprot)

A Fas apoptotic inhibitory molecule 1 that is encoded in the genome of human.


KLH11_HUMAN Kelch-like protein 11 (sprot)

A kelch-like protein 11 that is encoded in the genome of human.


INT10_HUMAN Integrator complex subunit 10 (sprot)

An integrator complex subunit 10 that is encoded in the genome of human.


KTU_HUMAN Protein kintoun (sprot)

A protein kintoun that is encoded in the genome of human.


TBCC1_HUMAN TBCC domain-containing protein 1 (sprot)

A TBCC domain-containing protein 1 that is encoded in the genome of human.


RT18A_HUMAN Large ribosomal subunit protein mL66 (sprot)

A 39S ribosomal protein S18a, mitochondrial that is encoded in the genome of human.


PNPO_HUMAN Pyridoxine-5'-phosphate oxidase (sprot)

A pyridoxine-5'-phosphate oxidase that is encoded in the genome of human.


pyridoxamine phosphate oxidase activity

Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH4+ + hydrogen peroxide. This activity can also oxidize pyridoxine 5'-phosphate to  pyridoxal 5'-phosphate + hydrogen peroxide.


pyridoxine biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.


pyridoxal phosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.


ARMC1_HUMAN Armadillo repeat-containing protein 1 (sprot)

An armadillo repeat-containing protein 1 that is encoded in the genome of human.


RPC5_HUMAN DNA-directed RNA polymerase III subunit RPC5 (sprot)

A DNA-directed RNA polymerase III subunit RPC5 that is encoded in the genome of human.


SDA1_HUMAN Protein SDA1 homolog (sprot)

A protein SDA1 that is encoded in the genome of human.


TM38B_HUMAN Trimeric intracellular cation channel type B (sprot)

A trimeric intracellular cation channel type B that is encoded in the genome of human.


CS073_HUMAN Putative uncharacterized protein C19orf73 (sprot)

A protein that is a translation product of the C19orf73 gene in human.


PAPD1_HUMAN Poly(A) RNA polymerase, mitochondrial (sprot)

A poly(A) RNA polymerase, mitochondrial that is encoded in the genome of human.


AIG1_HUMAN Androgen-induced gene 1 protein (sprot)

An androgen-induced gene 1 protein that is encoded in the genome of human.


THAP1_HUMAN THAP domain-containing protein 1 (sprot)

A THAP domain-containing protein 1 that is encoded in the genome of human.


RNF12_HUMAN E3 ubiquitin-protein ligase RLIM (sprot)

An E3 ubiquitin-protein ligase RLIM that is encoded in the genome of human.


HAUS2_HUMAN HAUS augmin-like complex subunit 2 (sprot)

A HAUS augmin-like complex subunit 2 that is encoded in the genome of human.


NLE1_HUMAN Notchless protein homolog 1 (sprot)

A notchless protein homolog 1 that is encoded in the genome of human.


NECP2_HUMAN Adaptin ear-binding coat-associated protein 2 (sprot)

An adaptin ear-binding coat-associated protein 2 that is encoded in the genome of human.


clathrin vesicle coat

A clathrin coat found on a vesicle.


ZN358_HUMAN Zinc finger protein 358 (sprot)

A zinc finger protein 358 that is encoded in the genome of human.


RPC2_HUMAN DNA-directed RNA polymerase III subunit RPC2 (sprot)

A DNA-directed RNA polymerase III subunit RPC2 that is encoded in the genome of human.


RBM28_HUMAN RNA-binding protein 28 (sprot)

An RNA-binding protein 28 that is encoded in the genome of human.


ANO10_HUMAN Anoctamin-10 (sprot)

An anoctamin-10 that is encoded in the genome of human.


FANCL_HUMAN E3 ubiquitin-protein ligase FANCL (sprot)

An E3 ubiquitin-protein ligase FANCL that is encoded in the genome of human.


PKHJ1_HUMAN Pleckstrin homology domain-containing family J member 1 (sprot)

A pleckstrin homology domain-containing family J member 1 that is encoded in the genome of human.


RBM22_HUMAN Pre-mRNA-splicing factor RBM22 (sprot)

A pre-mRNA-splicing factor RBM22 that is encoded in the genome of human.


BSDC1_HUMAN BSD domain-containing protein 1 (sprot)

A BSD domain-containing protein 1 that is encoded in the genome of human.


GPTC2_HUMAN G patch domain-containing protein 2 (sprot)

A G patch domain-containing protein 2 that is encoded in the genome of human.


DMAC2_HUMAN Distal membrane-arm assembly complex protein 2 (sprot)

A distal membrane-arm assembly complex protein 2 that is encoded in the genome of human.


WDR70_HUMAN WD repeat-containing protein 70 (sprot)

A WD repeat-containing protein 70 that is encoded in the genome of human.


TMM51_HUMAN Transmembrane protein 51 (sprot)

A transmembrane protein 51 that is encoded in the genome of human.


MED9_HUMAN Mediator of RNA polymerase II transcription subunit 9 (sprot)

A mediator of RNA polymerase II transcription subunit 9 that is encoded in the genome of human.


RFOX1_HUMAN RNA binding protein fox-1 homolog 1 (sprot)

An RNA binding protein fox-1 homolog 1 that is encoded in the genome of human.


ARGL1_HUMAN Arginine and glutamate-rich protein 1 (sprot)

An arginine and glutamate-rich protein 1 that is encoded in the genome of human.


IFT57_HUMAN Intraflagellar transport protein 57 homolog (sprot)

An intraflagellar transport protein 57 that is encoded in the genome of human.


TM45A_HUMAN Transmembrane protein 45A (sprot)

A transmembrane protein 45A that is encoded in the genome of human.


TM248_HUMAN Transmembrane protein 248 (sprot)

A transmembrane protein 248 that is encoded in the genome of human.


BEX4_HUMAN Protein BEX4 (sprot)

A protein BEX4 that is encoded in the genome of human.


S52A1_HUMAN Solute carrier family 52, riboflavin transporter, member 1 (sprot)

A solute carrier family 52, riboflavin transporter, member 1 that is encoded in the genome of human.


RN216_HUMAN E3 ubiquitin-protein ligase RNF216 (sprot)

An E3 ubiquitin-protein ligase RNF216 that is encoded in the genome of human.


TM242_HUMAN Transmembrane protein 242 (sprot)

A transmembrane protein 242 that is encoded in the genome of human.


SPAT6_HUMAN Spermatogenesis-associated protein 6 (sprot)

A spermatogenesis-associated protein 6 that is encoded in the genome of human.


SLTM_HUMAN SAFB-like transcription modulator (sprot)

A SAFB-like transcription modulator that is encoded in the genome of human.


BCD1_HUMAN Box C/D snoRNA protein 1 (sprot)

A Box C/D snoRNA protein 1 that is encoded in the genome of human.


ASND1_HUMAN Asparagine synthetase domain-containing protein 1 (sprot)

An asparagine synthetase domain-containing protein 1 that is encoded in the genome of human.


SMOX_HUMAN Spermine oxidase (sprot)

A spermine oxidase that is encoded in the genome of human.


Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide.


N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity

Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide.


polyamine catabolic process

The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups.


CUED1_HUMAN CUE domain-containing protein 1 (sprot)

A CUE domain-containing protein 1 that is encoded in the genome of human.


FKB14_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP14 (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP14 that is encoded in the genome of human.


FBX34_HUMAN F-box only protein 34 (sprot)

An F-box only protein 34 that is encoded in the genome of human.


GPT2L_HUMAN G patch domain-containing protein 2-like (sprot)

A G patch domain-containing protein 2-like that is encoded in the genome of human.


PHAG1_HUMAN Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (sprot)

A phosphoprotein associated with glycosphingolipid-enriched microdomains 1 that is encoded in the genome of human.


CN119_HUMAN Uncharacterized protein C14orf119 (sprot)

An uncharacterized protein C14orf119 that is encoded in the genome of human.


MCUB_HUMAN Calcium uniporter regulatory subunit MCUb, mitochondrial (sprot)

A calcium uniporter regulatory subunit MCUb, mitochondrial that is encoded in the genome of human.


PIHD1_HUMAN PIH1 domain-containing protein 1 (sprot)

A PIH1 domain-containing protein 1 that is encoded in the genome of human.


TORC1 complex assembly

The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex.


PARI_HUMAN PCNA-interacting partner (sprot)

A PCNA-interacting partner that is encoded in the genome of human.


F118A_HUMAN Protein FAM118A (sprot)

A protein FAM118A that is encoded in the genome of human.


RMND1_HUMAN Required for meiotic nuclear division protein 1 homolog (sprot)

A required for meiotic nuclear division protein 1 that is encoded in the genome of human.


ZN446_HUMAN Zinc finger protein 446 (sprot)

A zinc finger protein 446 that is encoded in the genome of human.


PK1IP_HUMAN p21-activated protein kinase-interacting protein 1 (sprot)

A p21-activated protein kinase-interacting protein 1 that is encoded in the genome of human.


HIF1N_HUMAN Hypoxia-inducible factor 1-alpha inhibitor (sprot)

A hypoxia-inducible factor 1-alpha inhibitor that is encoded in the genome of human.


Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.


AKIP_HUMAN Small ribosomal subunit protein mS38 (sprot)

An aurora kinase A-interacting protein that is encoded in the genome of human.


OXSM_HUMAN 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (sprot)

A 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial that is encoded in the genome of human.


short-chain fatty acid biosynthetic process

The chemical reactions and pathways resulting in the formation of a fatty acid with an aliphatic tail of less than 6 carbons.


GID8_HUMAN Glucose-induced degradation protein 8 homolog (sprot)

A glucose-induced degradation protein 8 homolog that is encoded in the genome of human.


RM22_HUMAN Large ribosomal subunit protein uL22m (sprot)

A 39S ribosomal protein L22, mitochondrial that is encoded in the genome of human.


CZIB_HUMAN CXXC motif containing zinc binding protein (sprot)

A CXXC motif containing zinc binding protein that is encoded in the genome of human.


BABA1_HUMAN BRISC and BRCA1-A complex member 1 (sprot)

A BRISC and BRCA1-A complex member 1 that is encoded in the genome of human.


HPIP_HUMAN Host cell factor C1 regulator 1 (sprot)

A host cell factor C1 regulator 1 that is encoded in the genome of human.


CLN6_HUMAN Ceroid-lipofuscinosis neuronal protein 6 (sprot)

A ceroid-lipofuscinosis neuronal protein 6 that is encoded in the genome of human.


NRK1_HUMAN Nicotinamide riboside kinase 1 (sprot)

A nicotinamide riboside kinase 1 that is encoded in the genome of human.


CB042_HUMAN Uncharacterized protein C2orf42 (sprot)

An uncharacterized protein C2orf42 that is encoded in the genome of human.


PLAT2_HUMAN Phospholipase A and acyltransferase 2 (sprot)

A phospholipase A and acyltransferase 2 that is encoded in the genome of human.


ASB6_HUMAN Ankyrin repeat and SOCS box protein 6 (sprot)

An ankyrin repeat and SOCS box protein 6 that is encoded in the genome of human.


THG1_HUMAN Probable tRNA(His) guanylyltransferase (sprot)

A probable tRNA(His) guanylyltransferase that is encoded in the genome of human.


tRNA guanylyltransferase activity

Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.


tRNA 5'-end processing

The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.


stress-induced mitochondrial fusion

Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.


HPF1_HUMAN Histone PARylation factor 1 (sprot)

A histone PARylation factor 1 that is encoded in the genome of human.


IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 (sprot)

An interleukin-1 receptor-associated kinase 4 that is encoded in the genome of human.


UCKL1_HUMAN Uridine-cytidine kinase-like 1 (sprot)

A uridine-cytidine kinase-like 1 that is encoded in the genome of human.


GEMI8_HUMAN Gem-associated protein 8 (sprot)

A gem-associated protein 8 that is encoded in the genome of human.


TM160_HUMAN Transmembrane protein 160 (sprot)

A transmembrane protein 160 that is encoded in the genome of human.


TXN4B_HUMAN Thioredoxin-like protein 4B (sprot)

A thioredoxin-like protein 4B that is encoded in the genome of human.


NALP2_HUMAN NACHT, LRR and PYD domains-containing protein 2 (sprot)

A NACHT, LRR and PYD domains-containing protein 2 that is encoded in the genome of human.


Pyrin domain binding

Binding to a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.


AIRIM_HUMAN AFG2-interacting ribosome maturation factor (sprot)

A ribosome biogenesis protein C1orf109 that is encoded in the genome of human.


F120C_HUMAN Constitutive coactivator of PPAR-gamma-like protein 2 (sprot)

A constitutive coactivator of PPAR-gamma-like protein 2 that is encoded in the genome of human.


TSAP1_HUMAN tRNA selenocysteine 1-associated protein 1 (sprot)

A tRNA selenocysteine 1-associated protein 1 that is encoded in the genome of human.


COMD8_HUMAN COMM domain-containing protein 8 (sprot)

A COMM domain-containing protein 8 that is encoded in the genome of human.


DDIT4_HUMAN DNA damage-inducible transcript 4 protein (sprot)

A DNA damage-inducible transcript 4 protein that is encoded in the genome of human.


protein-containing complex disassembly

The disaggregation of a protein-containing macromolecular complex into its constituent components.


NDUBB_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial that is encoded in the genome of human.


SDHF2_HUMAN Succinate dehydrogenase assembly factor 2, mitochondrial (sprot)

A succinate dehydrogenase assembly factor 2, mitochondrial that is encoded in the genome of human.


protein-FAD linkage

The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).


RM16_HUMAN Large ribosomal subunit protein uL16m (sprot)

A 39S ribosomal protein L16, mitochondrial that is encoded in the genome of human.


NHP2_HUMAN H/ACA ribonucleoprotein complex subunit 2 (sprot)

An H/ACA ribonucleoprotein complex subunit 2 that is encoded in the genome of human.


rRNA pseudouridine synthesis

The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.


DJC28_HUMAN DnaJ homolog subfamily C member 28 (sprot)

A DnaJ homolog subfamily C member 28 that is encoded in the genome of human.


ABITM_HUMAN Protein Abitram (sprot)

A protein Abitram that is encoded in the genome of human.


OCAD1_HUMAN OCIA domain-containing protein 1 (sprot)

An OCIA domain-containing protein 1 that is encoded in the genome of human.


SOLH2_HUMAN Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 (sprot)

A spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 that is encoded in the genome of human.


ADPRS_HUMAN ADP-ribosylhydrolase ARH3 (sprot)

An ADP-ribosylhydrolase ARH3 that is encoded in the genome of human.


Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate.


ADP-ribosylserine hydrolase activity

Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.


peptidyl-serine ADP-deribosylation

The removal of ADP-ribose from ADP-ribosylserine.


MARH5_HUMAN E3 ubiquitin-protein ligase MARCHF5 (sprot)

An E3 ubiquitin-protein ligase MARCHF5 that is encoded in the genome of human.


RHBL2_HUMAN Rhomboid-related protein 2 (sprot)

A rhomboid-related protein 2 that is encoded in the genome of human.


HYPK_HUMAN Huntingtin-interacting protein K (sprot)

A huntingtin-interacting protein K that is encoded in the genome of human.


RAB20_HUMAN Ras-related protein Rab-20 (sprot)

A Ras-related protein Rab-20 that is encoded in the genome of human.


LYAR_HUMAN Cell growth-regulating nucleolar protein (sprot)

A cell growth-regulating nucleolar protein that is encoded in the genome of human.


T161A_HUMAN Transmembrane protein 161A (sprot)

A transmembrane protein 161A that is encoded in the genome of human.


IMPA3_HUMAN Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (sprot)

A Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase that is encoded in the genome of human.


3',5'-nucleotide bisphosphate phosphatase activity

Catalysis of the reaction: 3',5'-nucleoside bisphosphate + H20 = 5'-nucleoside monophosphate + phosphate.


MIC19_HUMAN MICOS complex subunit MIC19 (sprot)

A MICOS complex subunit MIC19 that is encoded in the genome of human.


ZSC32_HUMAN Zinc finger and SCAN domain-containing protein 32 (sprot)

A zinc finger and SCAN domain-containing protein 32 that is encoded in the genome of human.


MED29_HUMAN Mediator of RNA polymerase II transcription subunit 29 (sprot)

A mediator of RNA polymerase II transcription subunit 29 that is encoded in the genome of human.


DUS2L_HUMAN tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (sprot)

A tRNA-dihydrouridine synthase 2-like that is encoded in the genome of human.


tRNA-dihydrouridine20 synthase activity

Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) = H+ + a uracil20 in tRNA + NAD(P)H.


CKLF6_HUMAN CKLF-like MARVEL transmembrane domain-containing protein 6 (sprot)

A CKLF-like MARVEL transmembrane domain-containing protein 6 that is encoded in the genome of human.


ENK13_HUMAN Endogenous retrovirus group K member 13-1 Env polyprotein (sprot)

A protein that is a translation product of the ERVK13-1 gene in human.


TM260_HUMAN Transmembrane protein 260 (sprot)

A transmembrane protein 260 that is encoded in the genome of human.


WBP1L_HUMAN WW domain binding protein 1-like (sprot)

A WW domain binding protein 1-like that is encoded in the genome of human.


SYBU_HUMAN Syntabulin (sprot)

A syntabulin that is encoded in the genome of human.


SIR5_HUMAN NAD-dependent protein deacylase sirtuin-5, mitochondrial (sprot)

An NAD-dependent deacetylase sirtuin-5 that is encoded in the genome of human.


Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide.


regulation of ketone biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.


protein demalonylation

The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.


peptidyl-lysine demalonylation

The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.


protein desuccinylation

The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.


peptidyl-lysine desuccinylation

The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.


MKS1_HUMAN Tectonic-like complex member MKS1 (sprot)

A tectonic-like complex member MKS1 that is encoded in the genome of human.


smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


ELOV2_HUMAN Elongation of very long chain fatty acids protein 2 (sprot)

An elongation of very long chain fatty acids protein 2 that is encoded in the genome of human.


GFOD1_HUMAN Glucose-fructose oxidoreductase domain-containing protein 1 (sprot)

A glucose-fructose oxidoreductase domain-containing protein 1 that is encoded in the genome of human.


MIO_HUMAN GATOR complex protein MIOS (sprot)

A GATOR complex protein MIOS that is encoded in the genome of human.


The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.


MTMRA_HUMAN Myotubularin-related protein 10 (sprot)

A myotubularin-related protein 10 that is encoded in the genome of human.


NSMA3_HUMAN Sphingomyelin phosphodiesterase 4 (sprot)

A sphingomyelin phosphodiesterase 4 that is encoded in the genome of human.


sphingomyelin phosphodiesterase D activity

Catalysis of the reaction: H2O + sphingomyelin = ceramide 1-phosphate + choline + H+.


CWC25_HUMAN Pre-mRNA-splicing factor CWC25 homolog (sprot)

A pre-mRNA-splicing factor CWC25 homolog that is encoded in the genome of human.


TEX10_HUMAN Testis-expressed protein 10 (sprot)

A testis-expressed protein 10 that is encoded in the genome of human.


DCA16_HUMAN DDB1- and CUL4-associated factor 16 (sprot)

A DDB1- and CUL4-associated factor 16 that is encoded in the genome of human.


ZDHC7_HUMAN Palmitoyltransferase ZDHHC7 (sprot)

A palmitoyltransferase ZDHHC7 that is encoded in the genome of human.


negative regulation of catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.


regulation of protein localization to cell-cell junction

Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction.


CNTLN_HUMAN Centlein (sprot)

A centlein that is encoded in the genome of human.


THUM1_HUMAN THUMP domain-containing protein 1 (sprot)

A THUMP domain-containing protein 1 that is encoded in the genome of human.


P4HTM_HUMAN Transmembrane prolyl 4-hydroxylase (sprot)

A transmembrane prolyl 4-hydroxylase that is encoded in the genome of human.


PP14D_HUMAN Protein phosphatase 1 regulatory subunit 14D (sprot)

A protein phosphatase 1 regulatory subunit 14D that is encoded in the genome of human.


negative regulation of protein serine/threonine phosphatase activity

Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity.


TOR4A_HUMAN Torsin-4A (sprot)

A torsin-4A that is encoded in the genome of human.


TRM1_HUMAN tRNA (guanine(26)-N(2))-dimethyltransferase (sprot)

An N(2),N(2)-dimethylguanosine tRNA methyltransferase that is encoded in the genome of human.


RN186_HUMAN E3 ubiquitin-protein ligase RNF186 (sprot)

An E3 ubiquitin-protein ligase RNF186 that is encoded in the genome of human.


M4A12_HUMAN Membrane-spanning 4-domains subfamily A member 12 (sprot)

A membrane-spanning 4-domains subfamily A member 12 that is encoded in the genome of human.


PGPI_HUMAN Pyroglutamyl-peptidase 1 (sprot)

A pyroglutamyl-peptidase 1 that is encoded in the genome of human.


pyroglutamyl-peptidase activity

Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.


PAQR5_HUMAN Membrane progestin receptor gamma (sprot)

A membrane progestin receptor gamma that is encoded in the genome of human.


FXL12_HUMAN F-box/LRR-repeat protein 12 (sprot)

An F-box/LRR-repeat protein 12 that is encoded in the genome of human.


SIDT1_HUMAN SID1 transmembrane family member 1 (sprot)

A SID1 transmembrane family member 1 that is encoded in the genome of human.


MCM9_HUMAN DNA helicase MCM9 (sprot)

A DNA helicase MCM9 that is encoded in the genome of human.


MutLbeta complex binding

Binding to a MutLbeta mismatch repair complex.


MutSbeta complex binding

Binding to a MutSbeta mismatch repair complex.


recombinational interstrand cross-link repair

Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous DNA region.


mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication

A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.


MCM8-MCM9 complex

A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.


GDAP2_HUMAN Ganglioside-induced differentiation-associated protein 2 (sprot)

A ganglioside-induced differentiation-associated protein 2 that is encoded in the genome of human.


GIN1_HUMAN Gypsy retrotransposon integrase-like protein 1 (sprot)

A gypsy retrotransposon integrase-like protein 1 that is encoded in the genome of human.


NDE1_HUMAN Nuclear distribution protein nudE homolog 1 (sprot)

A nuclear distribution protein nudE homolog 1 that is encoded in the genome of human.


establishment of chromosome localization

The directed movement of a chromosome to a specific location.


ANR10_HUMAN Ankyrin repeat domain-containing protein 10 (sprot)

An ankyrin repeat domain-containing protein 10 that is encoded in the genome of human.


BABA2_HUMAN BRISC and BRCA1-A complex member 2 (sprot)

A BRISC and BRCA1-A complex member 2 that is encoded in the genome of human.


ING3_HUMAN Inhibitor of growth protein 3 (sprot)

An inhibitor of growth protein 3 that is encoded in the genome of human.


QPCTL_HUMAN Glutaminyl-peptide cyclotransferase-like protein (sprot)

A glutaminyl-peptide cyclotransferase-like protein that is encoded in the genome of human.


ZN586_HUMAN Zinc finger protein 586 (sprot)

A zinc finger protein 586 that is encoded in the genome of human.


ARL15_HUMAN ADP-ribosylation factor-like protein 15 (sprot)

An ADP-ribosylation factor-like protein 15 that is encoded in the genome of human.


KCTD5_HUMAN BTB/POZ domain-containing protein KCTD5 (sprot)

A BTB/POZ domain-containing protein KCTD5 that is encoded in the genome of human.


CARF_HUMAN CDKN2A-interacting protein (sprot)

A CDKN2A-interacting protein that is encoded in the genome of human.


DJB12_HUMAN DnaJ homolog subfamily B member 12 (sprot)

A DnaJ homolog subfamily B member 12 that is encoded in the genome of human.


ALKB4_HUMAN Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (sprot)

An alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 that is encoded in the genome of human.


cleavage furrow ingression

Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.


NSE4A_HUMAN Non-structural maintenance of chromosomes element 4 homolog A (sprot)

A non-structural maintenance of chromosomes element 4 homolog A that is encoded in the genome of human.


SAGE1_HUMAN Sarcoma antigen 1 (sprot)

A sarcoma antigen 1 that is encoded in the genome of human.


DDX43_HUMAN Probable ATP-dependent RNA helicase DDX43 (sprot)

A probable ATP-dependent RNA helicase DDX43 that is encoded in the genome of human.


GAR1_HUMAN H/ACA ribonucleoprotein complex subunit 1 (sprot)

An H/ACA ribonucleoprotein complex subunit 1 that is encoded in the genome of human.


STAB1_HUMAN Stabilin-1 (sprot)

A stabilin-1 that is encoded in the genome of human.


CLC5A_HUMAN C-type lectin domain family 5 member A (sprot)

A C-type lectin domain family 5 member A that is encoded in the genome of human.


S39A1_HUMAN Zinc transporter ZIP1 (sprot)

A zinc transporter ZIP1 that is encoded in the genome of human.


PP4R2_HUMAN Serine/threonine-protein phosphatase 4 regulatory subunit 2 (sprot)

A serine/threonine-protein phosphatase 4 regulatory subunit 2 that is encoded in the genome of human.


GALT8_HUMAN Probable polypeptide N-acetylgalactosaminyltransferase 8 (sprot)

A probable polypeptide N-acetylgalactosaminyltransferase 8 that is encoded in the genome of human.


BTG4_HUMAN Protein BTG4 (sprot)

A protein BTG4 that is encoded in the genome of human.


DPP3_HUMAN Dipeptidyl peptidase 3 (sprot)

A dipeptidyl peptidase 3 (human), isoforms 1, 2, and 4.


CLDN1_HUMAN Claudin domain-containing protein 1 (sprot)

A claudin domain-containing protein 1 that is encoded in the genome of human.


ASIC5_HUMAN Acid-sensing ion channel 5 (sprot)

An acid-sensing ion channel 5 that is encoded in the genome of human.


BARH2_HUMAN BarH-like 2 homeobox protein (sprot)

A BarH-like 2 homeobox protein that is encoded in the genome of human.


SCN3A_HUMAN Sodium channel protein type 3 subunit alpha (sprot)

A sodium channel protein type 3 subunit alpha that is encoded in the genome of human.


CA2D2_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-2 (sprot)

A voltage-dependent calcium channel subunit alpha-2/delta-2 that is encoded in the genome of human.


OBP2A_HUMAN Odorant-binding protein 2a (sprot)

An odorant-binding protein 2a that is encoded in the genome of human.


ST32B_HUMAN Serine/threonine-protein kinase 32B (sprot)

A serine/threonine-protein kinase 32B that is encoded in the genome of human.


NSMA2_HUMAN Sphingomyelin phosphodiesterase 3 (sprot)

A sphingomyelin phosphodiesterase 3 that is encoded in the genome of human.


neutral sphingomyelin phosphodiesterase activity

Catalysis of the reaction: H2O + sphingomyelin = ceramide + choline phosphate + H+ in a neutral environment.


polysaccharide transport

The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


sphingolipid mediated signaling pathway

The series of molecular signals mediated by a sphingolipid.


AATF_HUMAN Protein AATF (sprot)

A protein AATF that is encoded in the genome of human.


GTR8_HUMAN Solute carrier family 2, facilitated glucose transporter member 8 (sprot)

A solute carrier family 2, facilitated glucose transporter member 8 that is encoded in the genome of human.


TBA8_HUMAN Tubulin alpha-8 chain (sprot)

A tubulin alpha-8 chain that is encoded in the genome of human.


SCN3B_HUMAN Sodium channel subunit beta-3 (sprot)

A sodium channel subunit beta-3 that is encoded in the genome of human.


ETAA1_HUMAN Ewing's tumor-associated antigen 1 (sprot)

An Ewing's tumor-associated antigen 1 that is encoded in the genome of human.


SPNXC_HUMAN Sperm protein associated with the nucleus on the X chromosome C (sprot)

A sperm protein associated with the nucleus on the X chromosome C that is encoded in the genome of human.


SC5A4_HUMAN Probable glucose sensor protein SLC5A4 (sprot)

A solute carrier family 5 member 4 that is encoded in the genome of human.


DDX56_HUMAN Probable ATP-dependent RNA helicase DDX56 (sprot)

A probable ATP-dependent RNA helicase DDX56 that is encoded in the genome of human.


B3GN2_HUMAN N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (sprot)

An N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 that is encoded in the genome of human.


SNTG2_HUMAN Gamma-2-syntrophin (sprot)

A gamma-2-syntrophin that is encoded in the genome of human.


SPHK1_HUMAN Sphingosine kinase 1 (sprot)

A sphingosine kinase 1 that is encoded in the genome of human.


sphingoid catabolic process

The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.


regulation of endosomal vesicle fusion

Any process that modulates the frequency, rate or extent of endosomal vesicle fusion.


GOG6A_HUMAN Golgin subfamily A member 6A (sprot)

A golgin subfamily A member 6A that is encoded in the genome of human.


MTMR4_HUMAN Myotubularin-related protein 4 (sprot)

A myotubularin-related protein 4 that is encoded in the genome of human.


TE2IP_HUMAN Telomeric repeat-binding factor 2-interacting protein 1 (sprot)

A telomeric repeat-binding factor 2-interacting protein 1 that is encoded in the genome of human.


negative regulation of DNA recombination at telomere

Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.


SO1C1_HUMAN Solute carrier organic anion transporter family member 1C1 (sprot)

A solute carrier organic anion transporter family member 1C1 that is encoded in the genome of human.


ABI2_HUMAN Abl interactor 2 (sprot)

An Abl interactor 2 that is encoded in the genome of human.


DYH9_HUMAN Dynein axonemal heavy chain 9 (sprot)

A dynein axonemal heavy chain 9 that is encoded in the genome of human.


distal portion of axoneme

The portion of the axoneme that is close to the tip of the cilium.


HXC10_HUMAN Homeobox protein Hox-C10 (sprot)

A homeobox protein Hox-C10 that is encoded in the genome of human.


DACT1_HUMAN Dapper homolog 1 (sprot)

A dapper homolog 1 that is encoded in the genome of human.


regulation of nodal signaling pathway

Any process that modulates the frequency, rate or extent of nodal signaling pathway.


FA53C_HUMAN Protein FAM53C (sprot)

A protein FAM53C that is encoded in the genome of human.


FA13B_HUMAN Protein FAM13B (sprot)

A protein FAM13B that is encoded in the genome of human.


BCLF1_HUMAN Bcl-2-associated transcription factor 1 (sprot)

A Bcl-2-associated transcription factor 1 that is encoded in the genome of human.


ZDHC3_HUMAN Palmitoyltransferase ZDHHC3 (sprot)

A palmitoyltransferase ZDHHC3 that is encoded in the genome of human.


lipoprotein localization to membrane

A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.


APC11_HUMAN Anaphase-promoting complex subunit 11 (sprot)

An anaphase-promoting complex subunit 11 that is encoded in the genome of human.


KCNK4_HUMAN Potassium channel subfamily K member 4 (sprot)

A potassium channel subfamily K member 4 that is encoded in the genome of human.


mechanosensitived potassium channel activity

Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.


UTP6_HUMAN U3 small nucleolar RNA-associated protein 6 homolog (sprot)

A U3 small nucleolar RNA-associated protein 6 that is encoded in the genome of human.


PSD3_HUMAN PH and SEC7 domain-containing protein 3 (sprot)

A PH and SEC7 domain-containing protein 3 that is encoded in the genome of human.


COA4_HUMAN Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (sprot)

A coiled-coil-helix-coiled-coil-helix domain-containing protein 8 that is encoded in the genome of human.


DLL3_HUMAN Delta-like protein 3 (sprot)

A delta-like protein 3 that is encoded in the genome of human.


TAB2_HUMAN TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (sprot)

A TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 that is encoded in the genome of human.


TLR7_HUMAN Toll-like receptor 7 (sprot)

A Toll-like receptor 7 that is encoded in the genome of human.


RM39_HUMAN Large ribosomal subunit protein mL39 (sprot)

A 39S ribosomal protein L39, mitochondrial that is encoded in the genome of human.


EURL_HUMAN Protein EURL homolog (sprot)

A protein EURL that is encoded in the genome of human.


M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 (sprot)

A mitogen-activated protein kinase kinase kinase 20 that is encoded in the genome of human.


positive regulation of mitotic DNA damage checkpoint

Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.


FKB11_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP11 (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP11 that is encoded in the genome of human.


CP39A_HUMAN 24-hydroxycholesterol 7-alpha-hydroxylase (sprot)

A cytochrome P450 39A1 that is encoded in the genome of human.


TMOD3_HUMAN Tropomodulin-3 (sprot)

A tropomodulin-3 that is encoded in the genome of human.


GPR83_HUMAN G-protein coupled receptor 83 (sprot)

A G-protein coupled receptor 83 that is encoded in the genome of human.


BET1L_HUMAN BET1-like protein (sprot)

A BET1-like protein that is encoded in the genome of human.


RASLC_HUMAN Ras-like protein family member 12 (sprot)

A Ras-like protein family member 12 that is encoded in the genome of human.


DONS_HUMAN Protein downstream neighbor of Son (sprot)

A protein downstream neighbor of Son that is encoded in the genome of human.


ELOV5_HUMAN Elongation of very long chain fatty acids protein 5 (sprot)

An elongation of very long chain fatty acids protein 5 that is encoded in the genome of human.


CU062_HUMAN Uncharacterized protein C21orf62 (sprot)

An uncharacterized protein C21orf62 that is encoded in the genome of human.


MS18A_HUMAN Protein Mis18-alpha (sprot)

A protein Mis18-alpha that is encoded in the genome of human.


HAOX2_HUMAN 2-Hydroxyacid oxidase 2 (sprot)

A 2-hydroxyacid oxidase 2 that is encoded in the genome of human.


(S)-2-hydroxy-acid oxidase activity

Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.


CELR1_HUMAN Cadherin EGF LAG seven-pass G-type receptor 1 (sprot)

A cadherin EGF LAG seven-pass G-type receptor 1 that is encoded in the genome of human.


orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis

The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.


planar dichotomous subdivision of terminal units involved in lung branching morphogenesis

The process in which a lung bud bifurcates parallel to the plane of the previous bud.


lateral sprouting involved in lung morphogenesis

The process in which a branch forms along the side of the lung epithelial tube.


protein localization involved in establishment of planar polarity

Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.


CELR3_HUMAN Cadherin EGF LAG seven-pass G-type receptor 3 (sprot)

A cadherin EGF LAG seven-pass G-type receptor 3 that is encoded in the genome of human.


planar cell polarity pathway involved in axon guidance

Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance.


FAT2_HUMAN Protocadherin Fat 2 (sprot)

A protocadherin Fat 2 that is encoded in the genome of human.


RDH8_HUMAN Retinol dehydrogenase 8 (sprot)

A retinol dehydrogenase 8 that is encoded in the genome of human.


KBRS2_HUMAN NF-kappa-B inhibitor-interacting Ras-like protein 2 (sprot)

An NF-kappa-B inhibitor-interacting Ras-like protein 2 that is encoded in the genome of human.


KBRS1_HUMAN NF-kappa-B inhibitor-interacting Ras-like protein 1 (sprot)

An NF-kappa-B inhibitor-interacting Ras-like protein 1 that is encoded in the genome of human.


WSB2_HUMAN WD repeat and SOCS box-containing protein 2 (sprot)

A WD repeat and SOCS box-containing protein 2 that is encoded in the genome of human.


PLEK2_HUMAN Pleckstrin-2 (sprot)

A pleckstrin-2 that is encoded in the genome of human.


positive regulation of plasma membrane bounded cell projection assembly

Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly.


ZN226_HUMAN Zinc finger protein 226 (sprot)

A zinc finger protein 226 that is encoded in the genome of human.


UGGG2_HUMAN UDP-glucose:glycoprotein glucosyltransferase 2 (sprot)

A UDP-glucose:glycoprotein glucosyltransferase 2 that is encoded in the genome of human.


Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.


UDP-glucosylation

The covalent attachment of a UDP-glucose residue to a substrate molecule.


UGGG1_HUMAN UDP-glucose:glycoprotein glucosyltransferase 1 (sprot)

A UDP-glucose:glycoprotein glucosyltransferase 1 that is encoded in the genome of human.


CDK12_HUMAN Cyclin-dependent kinase 12 (sprot)

A cyclin-dependent kinase 12 that is encoded in the genome of human.


RRN3_HUMAN RNA polymerase I-specific transcription initiation factor RRN3 (sprot)

An RNA polymerase I-specific transcription initiation factor RRN3 that is encoded in the genome of human.


regulation of DNA-templated transcription initiation

Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.


T2R16_HUMAN Taste receptor type 2 member 16 (sprot)

A taste receptor type 2 member 16 that is encoded in the genome of human.


T2R14_HUMAN Taste receptor type 2 member 14 (sprot)

A taste receptor type 2 member 14 that is encoded in the genome of human.


T2R13_HUMAN Taste receptor type 2 member 13 (sprot)

A taste receptor type 2 member 13 that is encoded in the genome of human.


T2R10_HUMAN Taste receptor type 2 member 10 (sprot)

A taste receptor type 2 member 10 that is encoded in the genome of human.


TA2R9_HUMAN Taste receptor type 2 member 9 (sprot)

A taste receptor type 2 member 9 that is encoded in the genome of human.


TA2R8_HUMAN Taste receptor type 2 member 8 (sprot)

A taste receptor type 2 member 8 that is encoded in the genome of human.


TA2R7_HUMAN Taste receptor type 2 member 7 (sprot)

A taste receptor type 2 member 7 that is encoded in the genome of human.


TA2R5_HUMAN Taste receptor type 2 member 5 (sprot)

A taste receptor type 2 member 5 that is encoded in the genome of human.


TA2R4_HUMAN Taste receptor type 2 member 4 (sprot)

A taste receptor type 2 member 4 that is encoded in the genome of human.


TA2R3_HUMAN Taste receptor type 2 member 3 (sprot)

A taste receptor type 2 member 3 that is encoded in the genome of human.


TA2R1_HUMAN Taste receptor type 2 member 1 (sprot)

A taste receptor type 2 member 1/119 that is encoded in the genome of human.


RBAK_HUMAN RB-associated KRAB zinc finger protein (sprot)

An RB-associated KRAB zinc finger protein that is encoded in the genome of human.


CALY_HUMAN Neuron-specific vesicular protein calcyon (sprot)

A neuron-specific vesicular protein calcyon that is encoded in the genome of human.


positive regulation of retrograde axon cargo transport

Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.


IL20_HUMAN Interleukin-20 (sprot)

An interleukin-20 that is encoded in the genome of human.


interleukin-20 receptor binding

Binding to an interleukin-20 receptor.


PLK2_HUMAN Serine/threonine-protein kinase PLK2 (sprot)

A serine/threonine-protein kinase PLK2 that is encoded in the genome of human.


FAKD2_HUMAN FAST kinase domain-containing protein 2, mitochondrial (sprot)

A FAST kinase domain-containing protein 2, mitochondrial that is encoded in the genome of human.


TV23B_HUMAN Golgi apparatus membrane protein TVP23 homolog B (sprot)

A Golgi apparatus membrane protein TVP23 homolog B that is encoded in the genome of human.


MFRN1_HUMAN Mitoferrin-1 (sprot)

A mitoferrin-1 that is encoded in the genome of human.


iron import into the mitochondrion

The process in which iron is transported from the cytosol into the mitochondrial matrix.


GTSE1_HUMAN G2 and S phase-expressed protein 1 (sprot)

A G2 and S phase-expressed protein 1 that is encoded in the genome of human.


SIGL8_HUMAN Sialic acid-binding Ig-like lectin 8 (sprot)

A sialic acid-binding Ig-like lectin 8 that is encoded in the genome of human.


TECR_HUMAN Very-long-chain enoyl-CoA reductase (sprot)

A very-long-chain enoyl-CoA reductase that is encoded in the genome of human.


very-long-chain enoyl-CoA reductase activity

Catalysis of the reaction: a very-long-chain 2,3-saturated fatty acyl-CoA + NADP+ = a very-long-chain (2E)-enoyl-CoA + H+ + NADPH.


ERAP1_HUMAN Endoplasmic reticulum aminopeptidase 1 (sprot)

An endoplasmic reticulum aminopeptidase 1 that is encoded in the genome of human.


UBAP1_HUMAN Ubiquitin-associated protein 1 (sprot)

A ubiquitin-associated protein 1 that is encoded in the genome of human.


PA2G3_HUMAN Group 3 secretory phospholipase A2 (sprot)

A group 3 secretory phospholipase A2 that is encoded in the genome of human.


positive regulation of mast cell differentiation

Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


ARP10_HUMAN Actin-related protein 10 (sprot)

An actin-related protein 10 that is encoded in the genome of human.


PEN2_HUMAN Gamma-secretase subunit PEN-2 (sprot)

A gamma-secretase subunit PEN-2 that is encoded in the genome of human.


USE1_HUMAN Vesicle transport protein USE1 (sprot)

A vesicle transport protein USE1 that is encoded in the genome of human.


CISD1_HUMAN CDGSH iron-sulfur domain-containing protein 1 (sprot)

A CDGSH iron-sulfur domain-containing protein 1 that is encoded in the genome of human.


GGA3_HUMAN ADP-ribosylation factor-binding protein GGA3 (sprot)

An ADP-ribosylation factor-binding protein GGA3 that is encoded in the genome of human.


PDXL2_HUMAN Podocalyxin-like protein 2 (sprot)

A podocalyxin-like protein 2 that is encoded in the genome of human.


FMN2_HUMAN Formin-2 (sprot)

A formin-2 that is encoded in the genome of human.


homologous chromosome movement towards spindle pole in meiosis I anaphase

The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis I anaphase.


TLS1_HUMAN Splicing factor C9orf78 (sprot)

A splicing factor C9orf78 that is encoded in the genome of human.


U5 snRNA binding

Binding to a U5 small nuclear RNA (U5 snRNA).


RTEL1_HUMAN Regulator of telomere elongation helicase 1 (sprot)

A regulator of telomere elongation helicase 1 that is encoded in the genome of human.


strand displacement

The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.


negative regulation of telomere maintenance in response to DNA damage

Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.


positive regulation of telomeric loop disassembly

Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.


STMN3_HUMAN Stathmin-3 (sprot)

A stathmin-3 that is encoded in the genome of human.


PRR13_HUMAN Proline-rich protein 13 (sprot)

A proline-rich protein 13 that is encoded in the genome of human.


NLGN3_HUMAN Neuroligin-3 (sprot)

A neuroligin-3 that is encoded in the genome of human.


CLIC5_HUMAN Chloride intracellular channel protein 5 (sprot)

A chloride intracellular channel protein 5 that is encoded in the genome of human.


F120A_HUMAN Constitutive coactivator of PPAR-gamma-like protein 1 (sprot)

A constitutive coactivator of PPAR-gamma-like protein 1 that is encoded in the genome of human.


MOCS1_HUMAN Molybdenum cofactor biosynthesis protein 1 (sprot)

A molybdenum cofactor biosynthesis protein 1 that is encoded in the genome of human.


TREM2_HUMAN Triggering receptor expressed on myeloid cells 2 (sprot)

A triggering receptor expressed on myeloid cells 2 that is encoded in the genome of human.


positive regulation of antigen processing and presentation of peptide antigen via MHC class II

Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.


detection of peptidoglycan

The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.


regulation of toll-like receptor 6 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.


positive regulation of complement activation, classical pathway

Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.


negative regulation of cell activation

Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.


detection of lipoteichoic acid

The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.


regulation of macrophage inflammatory protein 1 alpha production

Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


import into cell

The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis.


regulation of hippocampal neuron apoptotic process

Any process that modulates the occurrence or rate of cell death by apoptotic process in hippocampal neurons.


regulation of plasma membrane bounded cell projection organization

Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections.


positive regulation of C-C chemokine receptor CCR7 signaling pathway

Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.


positive regulation of CAMKK-AMPK signaling cascade

Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade.


excitatory synapse pruning

The disaggregation of an excitatory synapse into its constituent components.


positive regulation of synapse pruning

Any process that activates or increases the frequency, rate or extent of synapse pruning.


positive regulation of CD40 signaling pathway

Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.


GDE1_HUMAN Glycerophosphodiester phosphodiesterase 1 (sprot)

A glycerophosphodiester phosphodiesterase 1 that is encoded in the genome of human.


Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.


Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H2O = sn-glycerol 3-phosphate + myo-inositol + H+.


ethanolamine metabolic process

The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).


EHF_HUMAN ETS homologous factor (sprot)

An ETS homologous factor that is encoded in the genome of human.


WWOX_HUMAN WW domain-containing oxidoreductase (sprot)

A WW domain-containing oxidoreductase that is encoded in the genome of human.


SMAL1_HUMAN SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (sprot)

A SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 that is encoded in the genome of human.


GPC5D_HUMAN G-protein coupled receptor family C group 5 member D (sprot)

A G-protein coupled receptor family C group 5 member D that is encoded in the genome of human.


GLTP_HUMAN Glycolipid transfer protein (sprot)

A glycolipid transfer protein that is encoded in the genome of human.


AHSP_HUMAN Alpha-hemoglobin-stabilizing protein (sprot)

An alpha-hemoglobin-stabilizing protein that is encoded in the genome of human.


SPG21_HUMAN Maspardin (sprot)

A maspardin that is encoded in the genome of human.


RM35_HUMAN Large ribosomal subunit protein bL35m (sprot)

A 39S ribosomal protein L35, mitochondrial that is encoded in the genome of human.


PLAC8_HUMAN Placenta-specific gene 8 protein (sprot)

A placenta-specific gene 8 protein that is encoded in the genome of human.


NINJ2_HUMAN Ninjurin-2 (sprot)

A ninjurin-2 that is encoded in the genome of human.


GPC5B_HUMAN G-protein coupled receptor family C group 5 member B (sprot)

A G-protein coupled receptor family C group 5 member B that is encoded in the genome of human.


PTTG3_HUMAN Putative pituitary tumor-transforming gene 3 protein (sprot)

A securin-3 that is encoded in the genome of human.


PTTG2_HUMAN Securin-2 (sprot)

A securin-2 that is encoded in the genome of human.


IL37_HUMAN Interleukin-37 (sprot)

An interleukin-37 that is encoded in the genome of human.


IL36B_HUMAN Interleukin-36 beta (sprot)

An interleukin-36 beta that is encoded in the genome of human.


IL36G_HUMAN Interleukin-36 gamma (sprot)

An interleukin-1 family member 9 that is encoded in the genome of human.


KCIP1_HUMAN Kv channel-interacting protein 1 (sprot)

A Kv channel-interacting protein 1 that is encoded in the genome of human.


GRHL1_HUMAN Grainyhead-like protein 1 homolog (sprot)

A grainyhead-like protein 1 that is encoded in the genome of human.


TF2L1_HUMAN Transcription factor CP2-like protein 1 (sprot)

A transcription factor CP2-like protein 1 that is encoded in the genome of human.


UBIP1_HUMAN Upstream-binding protein 1 (sprot)

An upstream-binding protein 1 that is encoded in the genome of human.


IF2B1_HUMAN Insulin-like growth factor 2 mRNA-binding protein 1 (sprot)

An insulin-like growth factor 2 mRNA-binding protein 1 that is encoded in the genome of human.


regulation of mRNA stability involved in response to stress

Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.