(R)-4-hydroxyphenyllactate dehydrogenase (NADPH) activity

Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.


regulation of cellodextrin catabolic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.


sevenless signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


negative regulation of nerve growth factor production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).


eoxin E4 synthase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.


medulla reticulospinal tract morphogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.


cellular response to lipoprotein particle stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.


FAT10 conjugating enzyme activity

Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.


Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.


snRNA methylation

The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.


regulation of vesicle docking

Any process that modulates the frequency, rate or extent of vesicle docking.


antennal development

The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.


angioblast cell differentiation

The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).


peptidyl-lysine malonylation

The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.


adult salivary gland boundary specification

Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.


The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.


perturbation by symbiont of host actin cytoskeleton via actin filament reorganization

The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cell-matrix recognition

Cell recognition that involves the interaction of the cell with the extracellular matrix.


mammary gland duct regression in males

The process in which the epithelium of the mammary duct is destroyed in males.


N-methyl nucleosidase activity

Catalysis of the reaction: 7-methylxanthosine + H2O = 7-methylxanthine + H+ + ribofuranose.


phosphoserine-tRNA(Cys) ligase activity

Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).


protein localization to cytosolic proteasome complex

A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.


nucleobase binding

Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.


protein localization to actin cortical patch

A process in which a protein is transported to, or maintained in, an actin cortical patch.


phlobaphene metabolic process

The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


positive regulation of heart rate by norepinephrine

The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.


basket cell precursor proliferation

The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


gluconate dehydratase activity

Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.


bisdemethoxycurcumin synthase activity

Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.


Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.


Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.


1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming)

Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


glial cell migration in anterior lateral line nerve

The movement of a glial cell along the axons in the anterior lateral line nerve.


regulation of proline import across plasma membrane

Any process that modulates the frequency, rate or extent of proline import into cell.


bromide peroxidase activity

Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.


regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.


schizogony

Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.


inhibitory C-type lectin receptor signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.


vacuole-mitochondria membrane tethering

The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.


Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.


Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.


disruption of host cell envelope during viral entry

The disruption of host cell envelope by viral proteins during virus entry.


plasmid maintenance

The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.


cell growth mode switching, filamentous to budding

The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.


regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


cellular response to diosgenin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.


propan-2-ol metabolic process

The chemical reactions and pathways involving propan-2-ol.


dehiscence

The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.


isoflavonoid metabolic process

The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.


sesamin synthase activity

Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O.


CCL19-activated CCR7 signaling pathway

The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


anhydrosialidase activity

Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.


Mo-molybdopterin cofactor catabolic process

The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


phosphogluconate dehydratase activity

Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O.


Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside.


quinoline 2-oxidoreductase activity

Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.


negative regulation of lamellocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.


negative regulation of cell differentiation involved in stem cell population maintenance

Any negative regulation of cell differentiation that is involved in stem cell population maintenance.


Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.


slime layer organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.


protein-heme P460 linkage

The linkage of protein to heme P460.


regulation of neurotransmitter loading into synaptic vesicle

Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.


D-arabitol catabolic process to xylulose 5-phosphate

The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.


RNA polymerase IV activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


verruculogen biosynthetic process

The chemical reactions and pathways resulting in the formation of verruculogen.


anaerobic fructose catabolic process

The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.


molybdenum cofactor cytidylyltransferase activity

Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.


histidine N-acetyltransferase activity

Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H+.


positive regulation of nematode larval development

Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


eye-antennal disc morphogenesis

The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.


negative regulation of L-dopa decarboxylase activity

Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.


regulation of foraging behavior

Any process that modulates the frequency, rate or extent of foraging behavior.


gentisate decarboxylase activity

Catalysis of the reaction: 2,5-dihydroxybenzoate + H+ = CO2 + hydroquinone.


peptide cross-linking via L-cystine

The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.


positive regulation of systemic acquired resistance

Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.


gibberellin biosynthetic process

The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


phytochrome chromophore biosynthetic process

The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.


myrtenol dehydrogenase activity

Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.


establishment of plant organ orientation

The process that determines the orientation of a plant organ or tissue with reference to an axis.


cardiac neuron fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.


response to desipramine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.


mannan biosynthetic process

The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.


fatty acid beta-oxidation, unsaturated, even number

A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


inorganic molecular entity transmembrane transporter activity

Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.


eukaryotic translation initiation factor 4F complex assembly

The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.


tRNA N-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA.


terpenoid catabolic process

The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.


positive regulation of oogonium development

Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.


alcohol O-hexanoyltransferase activity

Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.


cis-zeatin UDP glycosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP.


inosine kinase activity

Catalysis of the reaction: ATP + inosine = ADP + IMP.


The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.


negative regulation of metabolic activity involved in hibernation

The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.


cellular biogenic amine catabolic process

The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.


semaphorin-plexin signaling pathway involved in neuron projection guidance

Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.


Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD+ = 7,8-dihydroxykynurenate + H+ + NADH.


zeaxanthin bis(beta-D-glucoside) metabolic process

The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).


Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.


(+)-delta-cadinene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.


regulation of anterograde synaptic vesicle transport

Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.


protein C-linked glycosylation

A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.


hermaphrodite somatic sex determination

The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.


ornithine N-benzoyltransferase activity

Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H+.


regulation of xylan catabolic process

Any process that modulates the frequency, rate or extent of xylan catabolic process.


positive regulation of catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.


mesonephric distal tubule morphogenesis

The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.


morphine 6-dehydrogenase activity

Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.


iron-sulfur-molybdenum cofactor metabolic process

The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.


cellular response to cesium ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


bromoxynil nitrilase activity

Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH4. Involved in the bacterial degradation of the herbicide bromoxynil.


undecan-2-one biosynthetic process

The chemical reactions and pathways resulting in the formation of undecan-2-one.


UDP-D-xylose metabolic process

The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine

The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.


negative regulation of response to wounding

Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.


The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.


The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.


UMP/dUMP kinase activity

Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.


negative regulation of pulmonary blood vessel remodeling

Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.


Notch signaling pathway involved in camera-type eye photoreceptor fate commitment

The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.


3-oxo-dodecanoyl-ACP hydrolase activity

Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein].


adenylyltransferase activity

Catalysis of the transfer of an adenylyl group to an acceptor.


ABC-type oligogalacturonide transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).


Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.


negative regulation of small intestine smooth muscle contraction

Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.


specification of ovule identity

The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


4-phenanthrol sulfotransferase activity

Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.


high-affinity IgA receptor activity

Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.


anterograde trans-synaptic signaling by trans-synaptic protein complex

Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.


neuroblast fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.


RNA-binding transcription regulator activity

A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.


specification of metanephric distal tubule identity

The process in which the distal tubule of the metanephric nephron acquires its identity.


selenomethionine gamma-lyase activity

Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.


Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.


taxoid 7beta-hydroxylase activity

Catalysis of the reaction: taxusin + [reduced NADPH-hemoprotein reductase] + O2 = 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O and 2alpha-hydroxytaxusin + [reduced NADPH-hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O.


carbohydrate-importing ABC transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).


R1/R6 development

The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.


hexose oxidase activity

Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.


dihydropyrimidine dehydrogenase (NAD+) activity

Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.


negative regulation of cerebellar neuron development

Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.


organic cyclic compound metabolic process

The chemical reactions and pathways involving organic cyclic compound.


post-embryonic animal organ morphogenesis

Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.


imaginal disc development

The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).


determination of lung left/right asymmetry

Determination of the asymmetric location of the lungs with respect to the left and right halves of the organism.


oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.


delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity

Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+.


response to bisphenol A

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.


regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis

Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.


positive regulation of mammary placode formation by mesenchymal-epithelial signaling

Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.


neuropeptide F receptor activity

Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.


rhamnogalacturonan II metabolic process

The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.


pyoverdine biosynthetic process

The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.


regulation of somatic muscle development

Any process that regulates the rate, frequency or extent of somatic muscle development.


2-oxo-acid reductase activity

Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.


negative regulation of alcohol biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.


tolerance induction in gut-associated lymphoid tissue

Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).


raucaffricine beta-glucosidase activity

Catalysis of the reaction: H2O + raucaffricine = D-glucose + vomilenine.


Catalysis of the reaction: isovitexin + UDP-D-glucose = H+ + isovitexin 2''-O-beta-D-glucoside + UDP.


negative regulation of cartilage condensation

Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.


regulation of renal water transport

Any process that modulates the frequency, rate or extent of renal water transport.


fructan biosynthetic process

The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.


beta-hydroxybutyrate transmembrane transporter activity

Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.


vacuolar localization

Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.


nucleobase catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.


streptomycin metabolic process

The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


pyridine biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.


spindle pole body anchor activity

The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.


Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.


glucuronoside metabolic process

The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.


regulation of lateral root development

Any process that modulates the frequency, rate or extent of lateral root development.


Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H+ = 2,5-dioxopentanoate + CO2 + H2O.


instar larval or pupal morphogenesis

The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.


response to rest involved in regulation of muscle adaptation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.


P-type magnesium transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in).


Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.


stipitatonate decarboxylase activity

Catalysis of the reaction: H2O + stipitatonate = CO2 + H+ + stipitatate.


3-isopropylmalate dehydratase activity

Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.


negative regulation of humoral immune response

Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.


bicyclic nitroimidazole metabolic process

The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.


Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.


Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H+. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.


negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.


cysteine biosynthetic process via S-sulfo-L-cysteine

The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.


The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.


methylenetetrahydrofolate reductase (ferredoxin) activity

Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.


cellular response to resveratrol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.


negative regulation of prostaglandin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.


interleukin-16 production

The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


selenomethionine-tRNA ligase activity

Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met).


sperm plasma membrane disassembly

The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.


regulation of somitomeric trunk muscle development

Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.


GUU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GUU codon.


reception of an inductive signal

The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.


regulation of signal transduction involved in conjugation with cellular fusion

Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion.


B-1 B cell proliferation

The expansion of a B-1 B cell by cell division. Follows B cell activation.


interleukin-37 production

The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.


mitochondrion-plasma membrane adaptor activity

The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.


organic heteropentacyclic compound catabolic process

The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.


IDP catabolic process

The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.


dUTP metabolic process

The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.


Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.


auxin-activated signaling pathway

The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.


cytidine salvage

Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.


ornithine N5-monooxygenase activity

Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.


hexose metabolic process

The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


betaine reductase activity

Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.


positive regulation of flavonoid biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.


regulation of Wnt-mediated midbrain dopaminergic neuron differentiation

Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.


regulation of horizontal cell localization

Any process that modulates the frequency, rate or extent of horizontal cell localization.


positive regulation of ribosomal large subunit export from nucleus

Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.


Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.


lithocholate 6beta-hydroxylase activity

Catalysis of the reaction: H+ + lithocholate + NADPH + O2 = 6-beta-hydroxylithocholate + H2O + NADP+.


perithecium formation

The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.


secondary active cyanate transmembrane transporter activity

Enables the transfer of cyanate from one side of a membrane to the other.


N-acetylcitrulline deacetylase activity

Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.


negative regulation of hemocyte proliferation

Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.


Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.


negative regulation of cell wall organization or biogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.


thiocyanate catabolic process

The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.


sesquisabinene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene.


aldehyde-lyase activity

Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.


post-embryonic anal fin morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


positive regulation of the force of heart contraction by circulating norepinephrine

The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction.


regulation of inhibin secretion

Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.


proteinase-activated receptor activity

A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.


negative regulation of lactose biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.


low-affinity nitrate transmembrane transporter activity

Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


glycosyl compound biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosyl compound.


regulation of interphase mitotic telomere clustering

Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.


larval turning behavior

Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.


positive regulation of L-tyrosine import across plasma membrane

Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell.


guanosine pentaphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.


migration in host

The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


glucarate dehydratase activity

Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O.


cyanamide metabolic process

The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.


recruitment of helicase-primase complex to DNA lesions

The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair.


syringal lignin biosynthetic process

The chemical reactions and pathways resulting in the formation of syringal lignin.


negative regulation of gonad development

Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.


regulation of leukocyte mediated immunity

Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.


suppression of host autophagy

Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Pup transferase activity

Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.


acetylenecarboxylate hydratase activity, producing 3-oxopropanoate

Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.


Golgi vesicle uncoating

The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.


epithelium-like organization

The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins.


fruit abscission

The controlled shedding of a fruit.


sphingolipid delta-8 desaturase activity

Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).


pyloric canal smooth muscle contraction

A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.


GTP cyclohydrolase activity

Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.


perception of rate of movement

The series of events by which an organism senses the speed and direction of movement of the body and its parts.


intermediate filament depolymerization

Disassembly of intermediate filaments by the removal of component monomers from a filament.


masculinization of hermaphrodite soma

Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans.


glomerular epithelial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.


ammonium ion binding

Binding to ammonium ions (NH4+).


(Z)-gamma-bisabolene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.


D-pinitol dehydrogenase activity

Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADPH.


starch alpha-glucosidase activity

Catalysis of the reaction: starch + H2O = alpha-D-glucose.


alcohol dehydrogenase (cytochrome c) activity

Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+.


Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.


negative regulation of acylglycerol transport

Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport.


mesonephric tubule morphogenesis

The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.


centripetally migrating follicle cell migration

The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.


synthetic cannabinoid binding

Binding to synthetic cannabinoid.


transport-coupled glycolytic process through glucose-6-phosphate

The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.


lymphatic vascular process in circulatory system

A circulatory process that occurs at the level of the lymphatic vasculature.


regulation of pronephric nephron tubule development

Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.


xanthophore differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.


positive regulation of response to drug

Any process that activates or increases the frequency, rate or extent of response to drug.


tyramine receptor activity

Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.


negative regulation of deacetylase activity

Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity.


trinitrotoluene metabolic process

The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.


glutathionylspermidine amidase activity

Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.


stomach fundus smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.


interleukin-28A production

The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


type IV pilus assembly

The assembly from its constituent parts of a type IV pilus.


The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.


alkane catabolic process

The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.


R7 cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor.


ensheathment of neurons

The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.


response to oxidopamine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.


connective tissue growth factor production

The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


proton-dependent peptide secondary active transmembrane transporter activity

Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.


endosulfan diol dehydrogenase activity

Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-.


Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine.


flower calyx development

The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.


Wnt-Frizzled-LRP5/6 complex assembly

The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex.


inferior salivary nucleus development

The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.


negative regulation of response to type II interferon

Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


metanephric cap formation

The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.


positive regulation of granuloma formation

Any process that activates or increases the frequency, rate, or extent of granuloma formation.


granzyme B localization to T cell secretory granule

Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.


prevention of polyspermy during double fertilization

The regulation of double fertilization forming a zygote and endosperm process that ensures that only a single sperm cell fertilizes one egg cell and another single sperm cell fertilizes one central cell.


atrial cardiac muscle cell membrane repolarization

The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.


3-cyano-L-alanine biosynthetic process

The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.


kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP.


2-carene synthase activity

Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid.


Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.


Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.


positive regulation of estrone secretion

Any process that activates or increases the frequency, rate or extent of estrone secretion.


regulation of kainate selective glutamate receptor signaling pathway

Any process that modulates the frequency, rate or extent of tge kainate selective glutamate receptor signaling pathway.


stress response to zinc ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.


peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid

The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.


response to transition metal nanoparticle

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.


culmination involved in sorocarp development

The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.


ATPase-coupled carboxylic acid transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).


glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group

Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.


negative regulation of L-lysine import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.


Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.


regulation of cardiac ventricle formation

Any process that modulates the frequency, rate or extent of cardiac ventricle formation.


regulation of DNA primase activity

Any process that modulates the frequency, rate or extent of DNA primase activity.


cytoneme morphogenesis

The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.


tatiopterin biosynthetic process

The chemical reactions and pathways resulting in the formation of tatiopterin.


negative regulation of cellular response to alcohol

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.


Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2.


thymidylate synthase (FAD) activity

Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.


cellular response to sodium phosphate

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.


nucleoside monophosphate metabolic process

The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.


cell wall integrity MAPK cascade

A MAPK cascade that contributes to cell wall organization or biogenesis.


positive regulation of the force of heart contraction by neuronal epinephrine

The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.


embryonic heart tube formation via epithelial folding

The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.


adhesin autotransporter activity

Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively.


positive regulation of apoptotic process in bone marrow cell

Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.


coenzyme M metabolic process

The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


2-dehydro-3-deoxygluconokinase activity

Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H+.


regulation of pigmentation

Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.


isoquinoline alkaloid biosynthetic process

The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


regulation of apoptotic process involved in metanephric nephron tubule development

Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.


regulation of short-day photoperiodism, flowering

Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.


Hulle cell development

The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


positive regulation of muscle cell apoptotic process

Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


ta-siRNA processing

A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs.


cardiolipin synthase activity

Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.


positive regulation of stomatal complex development

Any process that activates or increases the frequency, rate or extent of stomatal complex development.


endothelial stalk cell fate specification

The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout.


radial glial cell fate commitment in forebrain

The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.


hydroperoxide reductase activity

Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.


retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.


The 2-hydroxyisobutyrylation of a lysine residue in a protein.


fibroblast growth factor receptor signaling pathway involved in lung induction

The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.


double fertilization forming a zygote and endosperm

Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.


protein localization to mitotic spindle midzone

A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.


ABC-type ferric-enterobactin transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).


nitrite efflux transmembrane transporter activity

Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.


UDP-D-apiose biosynthetic process

The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


thylakoid membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.


cellular response to phenylpropanoid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.


cephalosporin C catabolic process

The chemical reactions and pathways resulting in the breakdown of cephalosporin C.


regulation of primary heart field cardioblast proliferation

Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle.


vacuole inheritance

The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.


methane monooxygenase activity

Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.


response to fluoxetine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.


cellular response to 4-nitroquinoline N-oxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.


mechanosensitive monoatomic cation channel activity

Enables the transmembrane transfer of a monoatomic cation by a channel that opens in response to a mechanical stress.


phenylalanine 4-hydroxylase (N10-formyl-tetrahydrofolate dependent) activity

Catalysis of the reaction: L-phenylalanine + O2 + an N10-formyl-tetrahydrofolate <=> L-tyrosine + a 10-formyltetrahydrofolate-4a-carbinolamine.


putrescine biosynthetic process from arginine

The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.


naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity

Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA.


protein catenane formation

The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.


cellular response to sulfate starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.


response to antimycin A

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.


adhesion of symbiont hyphopodium to host

The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.


negative regulation of ductus arteriosus closure

Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure.


macrophage tolerance induction

A process involving any mechanism for tolerance induction in macrophages.


glycol metabolic process

The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.


negative regulation of signal transduction in absence of ligand

Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.


envenomation resulting in fibrinolysis in another organism

The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism.


mitochondrial outer membrane fusion

The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.


fructose 5-dehydrogenase (NADP+) activity

Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH.


imaginal disc-derived appendage development

The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.


rhamnulokinase activity

Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.


Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde.


cell wall polysaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.


urinary tract smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.


positive regulation of septum digestion after cytokinesis

Any process that activates or increases the frequency, rate or extent of the process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.


positive regulation of intraciliary retrograde transport

Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport.


uracil salvage

Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.


nicotine metabolic process

The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.


modulation by symbiont of host innate immune response MAPK kinase signaling

Any process in which an organism modulates the frequency, rate or extent of a host MAP kinase-mediated signal transduction pathway during the host innate immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


The chemical reactions and pathways involving 18-methylnonadec-1-ene.


somatic diversification of DSCAM-based immune receptors

The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects.


glial cell migration in posterior lateral line nerve

The movement of a glial cell along the axons in the posterior lateral line nerve.


negative regulation of cell proliferation in bone marrow

Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow.


Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.


aerobic respiration, using ferrous ions as electron donor

The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.


regulation of pigment cell differentiation

Any process that modulates the frequency, rate or extent of pigmented cell differentiation.


methylsilanetriol hydroxylase activity

Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol.


undecaprenol kinase activity

Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.


compound eye pigment cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a compound eye pigment cell, a cell of the retina containing screening pigments that functions to screen photoreceptors from light leaking from adjacent ommatidia.


bicyclomycin transmembrane transporter activity

Enables the transfer of bicyclomycin from one side of a membrane to the other. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.


plasmid copy number maintenance

The maintenance of the number of copies of extrachromosomal plasmid DNA.


type I hypersensitivity mediated by mast cells

An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.


regulation of hair follicle cell proliferation

Any process that modulates the frequency, rate or extent of hair follicle cell proliferation.


suppression by virus of host cell lysis in response to superinfection

The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus.


single-species biofilm formation

A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.


Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-.


dCTP metabolic process

The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate.


branching involved in submandibular gland morphogenesis

The process in which the branching structure of the submandibular gland is generated and organized.


regulation of transformation of host cell by virus

Any process that modulates the frequency, rate or extent of transformation of host cell by virus.


wybutosine metabolic process

The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.


proline catabolic process to 2-oxoglutarate

The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate.


spore dispersal

Any process in which an organism disseminates its spores.


vibriobactin biosynthetic process

The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae.


regulation of potassium:proton exchanging ATPase activity

Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.


m-cresol metabolic process

The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes.


regulation of protein folding

Any process that modulates the frequency, rate or extent of protein folding.


histone H3K27 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27).


regulation of cardiac muscle myoblast proliferation

Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation.


positive regulation of apolipoprotein A-I-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.


cardiac muscle adaptation

The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.


oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen.


single-species submerged biofilm formation

A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.


Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7.


negative regulation of maternal process involved in parturition

Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition.


posterior lateral line nerve glial cell development

The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate.


cell-cell adhesion involved in sealing an epithelial fold

The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.


cellular component organization or biogenesis

A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.


envenomation resulting in negative regulation of high voltage-gated calcium channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism.


imaginal disc fusion, thorax closure

The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.


soyasapogenol E UDP-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + soyasapogenol E <=> UDP + a soyasapogenol E monoglucoside.


negative regulation of response to biotic stimulus

Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.


cotyledon boundary formation

The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained.


cardioblast proliferation

The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


iron-sulfur transferase activity

Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).


antigen sampling in mucosal-associated lymphoid tissue

The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.


regulation of nerve growth factor production

Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).


aryl-aldehyde oxidase activity

Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.


Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH.


glycine betaine metabolic process

The chemical reactions and pathways involving glycine betaine, N-trimethylglycine.


cellular response to codeine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.


behavioral response to chemical pain

Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.


tensidol B biosynthetic process

The chemical reactions and pathways resulting in the formation of tensidol B.


internode patterning

Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.


aromatic amino acid family biosynthetic process, prephenate pathway

The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate.


chondroitin B lyase activity

Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.


akinete formation

The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.


telomerase catalytic core complex assembly

The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex.


envenomation resulting in negative regulation of calcium channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism.


colnelenate synthase activity

Catalysis of the reaction: (10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate <=> colnelenate + H2O.


lombricine kinase activity

Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine.


endothelial tube formation

The developmental process pertaining to the initial formation of an endothelial tube.


Atg1/ULK1 kinase complex assembly

The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex.


taxoid 14-beta-hydroxylase activity

Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.


sinapate 1-glucosyltransferase activity

Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.


endocrine process

The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.


branched 1,3-beta-D-glucan synthase activity

Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + a branched [(1->3)-beta-D-glucosyl](n+1).


regulation of conidiophore development

Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


2-haloacid dehalogenase (configuration-inverting) activity

Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.


Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H+.


C4-dicarboxylate transmembrane transporter activity

Enables the transfer of C4-dicarboxylate from one side of a membrane to the other.


cell junction disassembly

The disaggregation of a cell junction into its constituent components.


regulation of transferase activity

Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.


6-oxocampestanol hydroxylase activity

Catalysis of the reaction: H+ + 6-oxocampestanol + O2 + NADPH = cathasterone + H2O + NADP.


cis-2-enoyl-CoA reductase (NADPH) activity

Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH.


epithelial cell differentiation involved in salivary gland development

The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.


Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP.


regulation of cellular response to oxidopamine

Any process that modulates the frequency, rate or extent of cellular response to oxidopamine.


presynaptic process involved in chemical synaptic transmission

The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.


regulation of oogenesis

Any process that modulates the frequency, rate or extent of oogenesis.


9-cis-10'-apo-beta-carotenal cleavage oxygenase activity

Catalysis of the reaction: 9-cis-10'-apo-beta-carotenal + 2 O2 <=> carlactone + (2E,4E,6E)-7-hydroxy-4-methylhepta-2,4,6-trienal.


negative regulation of presynaptic cytosolic calcium concentration

Any process that decreases the concentration of calcium ions in the presynaptic cytosol.


regulation of aspartate secretion

Any process that modulates the frequency, rate or extent of aspartate secretion.


periplasmic space organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi.


lysine-tRNA(Pyl) ligase activity

Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP.


secondary-alcohol oxidase activity

Catalysis of the reaction: secondary alcohol + O2 = H2O2 + ketone.


protein-phosphocysteine-mannitol phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


ATP phosphoribosyltransferase activity

Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.


negative regulation of phospholipid transport

Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.


peptidyl-isoleucine modification

The modification of peptidyl-isoleucine.


dTDP-rhamnose metabolic process

The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.


lyso-ornithine lipid acyltransferase activity

Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein].


maintenance of protease location in T cell secretory granule

A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


interleukin-32 production

The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


costunolide 3beta-hydroxylase activity

Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O.


interleukin-17A receptor activity

Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.


basophil mediated immunity

Any process involved in the carrying out of an immune response by a basophil.


Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.


Catalysis of the reaction: indole-3-acetyl-beta-4-D-glucose + H2O <=> H+ + indole-3-acetate + beta-D-glucose.


regulation of heterotypic cell-cell adhesion

Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion.


fructosamine biosynthetic process

The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.


The chemical reactions and pathways resulting in the formation of L-beta-ethynylserine. L-beta-ethynylserine is an antibiotic produced by Streptomyces bacteria.


acetylenic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of an acetylenic compound, any compound which contains a carbon-carbon triple bond (aka C#C).


formate dehydrogenase (cytochrome) activity

Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.


FAD-dependent histone H3K9me/H3K9me2 demethylase activity

Catalysis of the removal of a methyl group from a di- or a monomethyl-lysine residue at position 9 of the histone H3 protein. This is a flavin adenine dinucleotide (FAD)-dependent amine oxidation reaction.


histidine phosphotransfer kinase activity

Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.


hydrocarbon catabolic process

The chemical reactions and pathways resulting in the breakdown of a hydrocarbon, a compound consisting of carbon and hydrogen only.


paternal behavior

Male behaviors associated with the care and rearing offspring.


catalytic activity, acting on DNA

Catalytic activity that acts to modify DNA.


dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.


siroheme metabolic process

The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.


regulation of brain-derived neurotrophic factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.


GU repeat RNA binding

Binding to an RNA molecule containing GU repeats.


The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.


paclitaxel biosynthetic process

The chemical reactions and pathways resulting in the formation of paclitaxel, a tetracyclic diterpenoid isolated originally from the bark of the Pacific yew tree, Taxus brevifolia.


convergent extension involved in rhombomere morphogenesis

Any convergent extension that is involved in rhombomere morphogenesis.


epinephrine-mediated vasodilation

A vasodilation process resulting from secretion of epinephrine into the bloodstream or released by nerve endings.


peptidyl-histidine methylation, to form pros-methylhistidine

The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).


organ boundary specification between lateral organs and the meristem

The process in which boundaries between lateral organs and the meristem is established and maintained.


Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.


amorpha-4,11-diene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.


TNFSF11 receptor activity

Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function.


lateral pseudopodium retraction

The myosin-based contraction and retraction of a lateral pseudopodium.


Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H+.


Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.


clearance of cells from fusion plate by epithelial to mesenchymal transition

The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.


caffeate O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.


7,8-dihydromonapterin aldolase activity

Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol.


response to perphenazine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.


negative regulation of behavioral fear response

Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response.


CUG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CUG codon.


lung lobe development

The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.


dAMP biosynthetic process

The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).


regulation of R7 cell differentiation

Any process that modulates the frequency, rate or extent of R7 differentiation.


casbene synthase activity

Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.


negative regulation of development of symbiont in host

Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


anaerobic pectin catabolic process

The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen.


dihydroneopterin triphosphate 2'-epimerase activity

Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate.


benzil reductase [(S)-benzoin-forming] activity

Catalysis of the reaction: (S)-benzoin + NADP(3-) <=> benzil + NADPH(4-) + H+.


positive regulation of antigen processing and presentation

Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.