PDK1L_HUMAN Serine/threonine-protein kinase PDIK1L (sprot)

A serine/threonine-protein kinase PDIK1L that is encoded in the genome of human.


NDUF2_HUMAN NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (sprot)

An NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 that is encoded in the genome of human.


ZN567_HUMAN Zinc finger protein 567 (sprot)

A zinc finger protein 567 that is encoded in the genome of human.


CARTF_HUMAN Calcium-responsive transcription factor (sprot)

A calcium-responsive transcription factor that is encoded in the genome of human.


SIX5_HUMAN Homeobox protein SIX5 (sprot)

A homeobox protein SIX5 that is encoded in the genome of human.


KT222_HUMAN Keratin-like protein KRT222 (sprot)

A keratin-like protein KRT222 that is encoded in the genome of human.


CD033_HUMAN UPF0462 protein C4orf33 (sprot)

A UPF0462 protein C4orf33 that is encoded in the genome of human.


CCNQ_HUMAN Cyclin-Q (sprot)

A cyclin-Q that is encoded in the genome of human.


VPS52_HUMAN Vacuolar protein sorting-associated protein 52 homolog (sprot)

A vacuolar protein sorting-associated protein 52 that is encoded in the genome of human.


embryonic ectodermal digestive tract development

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.


GBRG1_HUMAN Gamma-aminobutyric acid receptor subunit gamma-1 (sprot)

A gamma-aminobutyric acid receptor subunit gamma-1 that is encoded in the genome of human.


BWR1B_HUMAN Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein (sprot)

A Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein that is encoded in the genome of human.


CF107_HUMAN Cilia- and flagella-associated protein 107 (sprot)

An uncharacterized protein C1orf158 that is encoded in the genome of human.


LYG1_HUMAN Lysozyme g-like protein 1 (sprot)

A lysozyme g-like protein 1 that is encoded in the genome of human.


FXL14_HUMAN F-box/LRR-repeat protein 14 (sprot)

An F-box/LRR-repeat protein 14 that is encoded in the genome of human.


NUP93_HUMAN Nuclear pore complex protein Nup93 (sprot)

A nuclear pore complex protein Nup93 that is encoded in the genome of human.


S11IP_HUMAN Serine/threonine-protein kinase 11-interacting protein (sprot)

A serine/threonine-protein kinase 11-interacting protein that is encoded in the genome of human.


ZN687_HUMAN Zinc finger protein 687 (sprot)

A zinc finger protein 687 that is encoded in the genome of human.


REXO1_HUMAN RNA exonuclease 1 homolog (sprot)

An RNA exonuclease 1 that is encoded in the genome of human.


CMTR1_HUMAN Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (sprot)

A cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 that is encoded in the genome of human.


cap1 mRNA methylation

Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.


LRC47_HUMAN Leucine-rich repeat-containing protein 47 (sprot)

A leucine-rich repeat-containing protein 47 that is encoded in the genome of human.


S6OS1_HUMAN Protein SIX6OS1 (sprot)

A protein SIX6OS1 that is encoded in the genome of human.


meiotic DNA double-strand break processing involved in reciprocal meiotic recombination

The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.


DOCK4_HUMAN Dedicator of cytokinesis protein 4 (sprot)

A dedicator of cytokinesis protein 4 that is encoded in the genome of human.


THMS1_HUMAN Protein THEMIS (sprot)

A protein THEMIS that is encoded in the genome of human.


positive T cell selection

The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.


negative T cell selection

The process of elimination of immature T cells which react strongly with self-antigens.


CP4Z2_HUMAN Putative inactive cytochrome P450 family member 4Z2 (sprot)


BATF2_HUMAN Basic leucine zipper transcriptional factor ATF-like 2 (sprot)

A basic leucine zipper transcriptional factor ATF-like 2 that is encoded in the genome of human.


BEST3_HUMAN Bestrophin-3 (sprot)

A bestrophin-3 that is encoded in the genome of human.


negative regulation of monoatomic ion transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


CLC4F_HUMAN C-type lectin domain family 4 member F (sprot)

A C-type lectin domain family 4 member F that is encoded in the genome of human.


DYNAP_HUMAN Dynactin-associated protein (sprot)

A protein that is a translation product of the DYNAP gene in human.


cellular response to ergosterol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.


K2C78_HUMAN Keratin, type II cytoskeletal 78 (sprot)

A keratin, type II cytoskeletal 78 that is encoded in the genome of human.


CRBG2_HUMAN Beta/gamma crystallin domain-containing protein 2 (sprot)

A beta/gamma crystallin domain-containing protein 2 that is encoded in the genome of human.


CAH13_HUMAN Carbonic anhydrase 13 (sprot)

A carbonic anhydrase 13 that is encoded in the genome of human.


THEM5_HUMAN Acyl-coenzyme A thioesterase THEM5 (sprot)

An acyl-coenzyme A thioesterase THEM5 that is encoded in the genome of human.


S39AB_HUMAN Zinc transporter ZIP11 (sprot)

A zinc transporter ZIP11 that is encoded in the genome of human.


MYO1H_HUMAN Unconventional myosin-Ih (sprot)

A myosin-Ih that is encoded in the genome of human.


CFA52_HUMAN Cilia- and flagella-associated protein 52 (sprot)

A cilia- and flagella-associated protein 52 that is encoded in the genome of human.


ARG28_HUMAN Rho guanine nucleotide exchange factor 28 (sprot)

A Rho guanine nucleotide exchange factor 28 that is encoded in the genome of human.


ZN710_HUMAN Zinc finger protein 710 (sprot)

A zinc finger protein 710 that is encoded in the genome of human.


YI025_HUMAN Putative uncharacterized protein FLJ37218 (sprot)


INT1_HUMAN Integrator complex subunit 1 (sprot)

An integrator complex subunit 1 that is encoded in the genome of human.


SYNE4_HUMAN Nesprin-4 (sprot)

A nesprin-4 that is encoded in the genome of human.


KLH34_HUMAN Kelch-like protein 34 (sprot)

A kelch-like protein 34 that is encoded in the genome of human.


H2B3B_HUMAN Histone H2B type 3-B (sprot)

A histone H2B type 3-B that is encoded in the genome of human.


RHG24_HUMAN Rho GTPase-activating protein 24 (sprot)

A Rho GTPase-activating protein 24 that is encoded in the genome of human.


PROM2_HUMAN Prominin-2 (sprot)

A prominin-2 that is encoded in the genome of human.


prominosome

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.


ANR35_HUMAN Ankyrin repeat domain-containing protein 35 (sprot)

An ankyrin repeat domain-containing protein 35 that is encoded in the genome of human.


GAPT_HUMAN Protein GAPT (sprot)

A protein GAPT that is encoded in the genome of human.


PLD6_HUMAN Mitochondrial cardiolipin hydrolase (sprot)

A phospholipase D6 that is encoded in the genome of human.


cardiolipin hydrolase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol), releasing phosphatidic acid (PA).


P granule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.


DEPD4_HUMAN DEP domain-containing protein 4 (sprot)

A DEP domain-containing protein 4 that is encoded in the genome of human.


UNC80_HUMAN Protein unc-80 homolog (sprot)

A protein unc-80 that is encoded in the genome of human.


ARM10_HUMAN Armadillo repeat-containing protein 10 (sprot)

An armadillo repeat-containing protein 10 that is encoded in the genome of human.


LYPD1_HUMAN Ly6/PLAUR domain-containing protein 1 (sprot)

An Ly6/PLAUR domain-containing protein 1 that is encoded in the genome of human.


ZCH24_HUMAN Zinc finger CCHC domain-containing protein 24 (sprot)

A zinc finger CCHC domain-containing protein 24 that is encoded in the genome of human.


GHDC_HUMAN GH3 domain-containing protein (sprot)

A GH3 domain-containing protein that is encoded in the genome of human.


PYRD2_HUMAN Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 (sprot)

A pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 that is encoded in the genome of human.


SYS1_HUMAN Protein SYS1 homolog (sprot)

A protein SYS1 that is encoded in the genome of human.


PELI3_HUMAN E3 ubiquitin-protein ligase pellino homolog 3 (sprot)

An E3 ubiquitin-protein ligase pellino homolog 3 that is encoded in the genome of human.


regulation of Toll signaling pathway

Any process that modulates the frequency, rate or extent of the Tl signaling pathway.


ZN619_HUMAN Zinc finger protein 619 (sprot)

A zinc finger protein 619 that is encoded in the genome of human.


STK40_HUMAN Serine/threonine-protein kinase 40 (sprot)

A serine/threonine-protein kinase 40 that is encoded in the genome of human.


ABD12_HUMAN Lysophosphatidylserine lipase ABHD12 (sprot)

A lysophosphatidylserine lipase ABHD12 that is encoded in the genome of human.


UB2J2_HUMAN Ubiquitin-conjugating enzyme E2 J2 (sprot)

A ubiquitin-conjugating enzyme E2 J2 that is encoded in the genome of human.


TM86A_HUMAN Lysoplasmalogenase-like protein TMEM86A (sprot)

A lysoplasmalogenase-like protein TMEM86A that is encoded in the genome of human.


Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.


CLASR_HUMAN CLK4-associating serine/arginine rich protein (sprot)

A CLK4-associating serine/arginine rich protein that is encoded in the genome of human.


AN36B_HUMAN Ankyrin repeat domain-containing protein 36B (sprot)

An ankyrin repeat domain-containing protein 36B that is encoded in the genome of human.


NLGN1_HUMAN Neuroligin-1 (sprot)

A neuroligin-1 that is encoded in the genome of human.


cytoskeletal matrix organization at active zone

The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.


cell-cell adhesion involved in synapse maturation

The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.


neurexin clustering involved in presynaptic membrane assembly

The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.


positive regulation of neuromuscular synaptic transmission

Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.


OSR2_HUMAN Protein odd-skipped-related 2 (sprot)

A protein odd-skipped-related 2 that is encoded in the genome of human.


FA43A_HUMAN Protein FAM43A (sprot)

A protein FAM43A that is encoded in the genome of human.


LTBP4_HUMAN Latent-transforming growth factor beta-binding protein 4 (sprot)

A latent-transforming growth factor beta-binding protein 4 that is encoded in the genome of human.


TM256_HUMAN Transmembrane protein 256 (sprot)

A UPF0382 inner membrane protein YgdD that is encoded in the genome of human.


S66A2_HUMAN Solute carrier family 66 member 2 (sprot)

A solute carrier family 66 member 2 that is encoded in the genome of human.


PIAS4_HUMAN E3 SUMO-protein ligase PIAS4 (sprot)

An E3 SUMO-protein ligase PIAS4 that is encoded in the genome of human.


limb epidermis development

The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.


EXAS1_HUMAN Uncharacterized protein EXOC3-AS1 (sprot)

A protein that is a translation product of the EXOC3-AS1 gene in human.


RUSC2_HUMAN AP-4 complex accessory subunit RUSC2 (sprot)

An AP-4 complex accessory subunit RUSC2 that is encoded in the genome of human.


CENPS_HUMAN Centromere protein S (sprot)

A centromere protein S that is encoded in the genome of human.


SVBP_HUMAN Small vasohibin-binding protein (sprot)

A small vasohibin-binding protein that is encoded in the genome of human.


regulation of metallopeptidase activity

Any process that modulates the frequency, rate or extent of metallopeptidase activity.


AGGF1_HUMAN Angiogenic factor with G patch and FHA domains 1 (sprot)

An angiogenic factor with G patch and FHA domains 1 that is encoded in the genome of human.


MUC20_HUMAN Mucin-20 (sprot)

A mucin-20 that is encoded in the genome of human.


NXPE1_HUMAN NXPE family member 1 (sprot)

An NXPE family member 1 that is encoded in the genome of human.


CJ111_HUMAN Putative uncharacterized protein RPP38-DT (sprot)


PGBD3_HUMAN PiggyBac transposable element-derived protein 3 (sprot)

A piggyBac transposable element-derived protein 3 that is encoded in the genome of human.


GPD1L_HUMAN Glycerol-3-phosphate dehydrogenase 1-like protein (sprot)

A glycerol-3-phosphate dehydrogenase 1-like protein that is encoded in the genome of human.


ELMD1_HUMAN ELMO domain-containing protein 1 (sprot)

An ELMO domain-containing protein 1 that is encoded in the genome of human.


MT1M_HUMAN Metallothionein-1M (sprot)

A metallothionein-1M that is encoded in the genome of human.


MIER2_HUMAN Mesoderm induction early response protein 2 (sprot)

A mesoderm induction early response protein 2 that is encoded in the genome of human.


OR2LD_HUMAN Olfactory receptor 2L13 (sprot)

An olfactory receptor 2L13 that is encoded in the genome of human.


CBARP_HUMAN Voltage-dependent calcium channel beta subunit-associated regulatory protein (sprot)

A voltage-dependent calcium channel beta subunit-associated regulatory protein that is encoded in the genome of human.


S35F6_HUMAN Solute carrier family 35 member F6 (sprot)

A solute carrier family 35 member F6 that encoded in the genome of human.


CIART_HUMAN Circadian-associated transcriptional repressor (sprot)

A circadian-associated transcriptional repressor that is encoded in the genome of human.


LAT4_HUMAN Large neutral amino acids transporter small subunit 4 (sprot)

A large neutral amino acids transporter small subunit 4 that is encoded in the genome of human.


L-methionine transmembrane transporter activity

Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.


L-phenylalanine transmembrane transporter activity

Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.


KDM8_HUMAN Bifunctional peptidase and arginyl-hydroxylase JMJD5 (sprot)

A bifunctional peptidase and arginyl-hydroxylase JMJD5 that is encoded in the genome of human.


Catalyzes the reaction: 2-oxoglutarate + [protein]-L-arginine + O2 = [protein]-(3R)-3-hydroxy-L-arginine + CO2 + succinate.


LRC25_HUMAN Leucine-rich repeat-containing protein 25 (sprot)

A leucine-rich repeat-containing protein 25 that is encoded in the genome of human.


MUC15_HUMAN Mucin-15 (sprot)

A mucin-15 that is encoded in the genome of human.


RHG18_HUMAN Rho GTPase-activating protein 18 (sprot)

A Rho GTPase-activating protein 18 that is encoded in the genome of human.


ZN786_HUMAN Zinc finger protein 786 (sprot)

A zinc finger protein 786 that is encoded in the genome of human.


TMTC2_HUMAN Protein O-mannosyl-transferase TMTC2 (sprot)

A protein O-mannosyl-transferase TMTC2 that is encoded in the genome of human.


PARP8_HUMAN Protein mono-ADP-ribosyltransferase PARP8 (sprot)

A protein mono-ADP-ribosyltransferase PARP8 that is encoded in the genome of human.


ASCC3_HUMAN Activating signal cointegrator 1 complex subunit 3 (sprot)

An activating signal cointegrator 1 complex subunit 3 that is encoded in the genome of human.


CLIP4_HUMAN CAP-Gly domain-containing linker protein 4 (sprot)

A CAP-Gly domain-containing linker protein 4 that is encoded in the genome of human.


EH1L1_HUMAN EH domain-binding protein 1-like protein 1 (sprot)

An EH domain-binding protein 1-like protein 1 that is encoded in the genome of human.


PLCD3_HUMAN 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (sprot)

A 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 that is encoded in the genome of human.


MTURN_HUMAN Maturin (sprot)

A maturin that is encoded in the genome of human.


MILK1_HUMAN MICAL-like protein 1 (sprot)

A MICAL-like protein 1 that is encoded in the genome of human.


cytoplasmic side of endosome membrane

The side (leaflet) of the endosome membrane that faces the cytoplasm.


G137C_HUMAN Integral membrane protein GPR137C (sprot)

An integral membrane protein GPR137C that is encoded in the genome of human.


TM130_HUMAN Transmembrane protein 130 (sprot)

A transmembrane protein 130 that is encoded in the genome of human.


TAFA2_HUMAN Chemokine-like protein TAFA-2 (sprot)

A chemokine-like protein TAFA-2 that is encoded in the genome of human.


BBS5_HUMAN Bardet-Biedl syndrome 5 protein (sprot)

A Bardet-Biedl syndrome 5 protein that is encoded in the genome of human.


METL4_HUMAN N(6)-adenine-specific methyltransferase METTL4 (sprot)

An N(6)-adenine-specific methyltransferase METTL4 that is encoded in the genome of human.


site-specific DNA-methyltransferase (adenine-specific) activity

Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.


U2 snRNA 2'-O-methyladenosine m6 methyltransferase activity

Catalysis of the reaction: a 2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-methionine = an N6-methyl-2'-O-methyladenosine in U2 snRNA + S-adenosyl-L-homocysteine + H+.


DNA methylation on adenine

The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule.


regulation of mitochondrial DNA replication

Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.


regulation of mitochondrial transcription

Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.


HROB_HUMAN Homologous recombination OB-fold protein (sprot)

A homologous recombination OB-fold protein that is encoded in the genome of human.


male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.


PPM1K_HUMAN Protein phosphatase 1K, mitochondrial (sprot)

A protein phosphatase 1K, mitochondrial that is encoded in the genome of human.


CADM2_HUMAN Cell adhesion molecule 2 (sprot)

A cell adhesion molecule 2 that is encoded in the genome of human.


ZN664_HUMAN Zinc finger protein 664 (sprot)

A zinc finger protein 664 that is encoded in the genome of human.


CMYA5_HUMAN Cardiomyopathy-associated protein 5 (sprot)

A cardiomyopathy-associated protein 5 that is encoded in the genome of human.


TXLNB_HUMAN Beta-taxilin (sprot)

A beta-taxilin that is encoded in the genome of human.


VPS8_HUMAN Vacuolar protein sorting-associated protein 8 homolog (sprot)

A vacuolar protein sorting-associated protein 8 that is encoded in the genome of human.


CORVET complex

A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.


TCAIM_HUMAN T-cell activation inhibitor, mitochondrial (sprot)

A T-cell activation inhibitor, mitochondrial that is encoded in the genome of human.


PALS1_HUMAN Protein PALS1 (sprot)

A protein PALS1 that is encoded in the genome of human.


protein localization to myelin sheath abaxonal region

Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.


PHTF2_HUMAN Protein PHTF2 (sprot)

A protein PHTF2 that is encoded in the genome of human.


GLT15_HUMAN Polypeptide N-acetylgalactosaminyltransferase 15 (sprot)

A polypeptide N-acetylgalactosaminyltransferase-like protein 2 that is encoded in the genome of human.


T132C_HUMAN Transmembrane protein 132C (sprot)

A transmembrane protein 132C that is encoded in the genome of human.


STAG2_HUMAN Cohesin subunit SA-2 (sprot)

A cohesin subunit SA-2 that is encoded in the genome of human.


SYNPO_HUMAN Synaptopodin (sprot)

A synaptopodin that is encoded in the genome of human.


modification of dendritic spine

Any process that modifies the structure of a dendritic spine.


FNBP4_HUMAN Formin-binding protein 4 (sprot)

A formin-binding protein 4 that is encoded in the genome of human.


LCORL_HUMAN Ligand-dependent nuclear receptor corepressor-like protein (sprot)

A ligand-dependent nuclear receptor corepressor-like protein that is encoded in the genome of human.


FBXW8_HUMAN F-box/WD repeat-containing protein 8 (sprot)

An F-box/WD repeat-containing protein 8 that is encoded in the genome of human.


LARG2_HUMAN Xylosyl- and glucuronyltransferase LARGE2 (sprot)

A xylosyl- and glucuronyltransferase LARGE2 that is encoded in the genome of human.


RDHE2_HUMAN Epidermal retinol dehydrogenase 2 (sprot)

An epidermal retinol dehydrogenase 2 that is encoded in the genome of human.


PRS35_HUMAN Inactive serine protease 35 (sprot)

An inactive serine protease 35 that is encoded in the genome of human.


GTPB8_HUMAN GTP-binding protein 8 (sprot)

A GTP-binding protein 8 that is encoded in the genome of human.


ZCHC7_HUMAN Zinc finger CCHC domain-containing protein 7 (sprot)

A zinc finger CCHC domain-containing protein 7 that is encoded in the genome of human.


S2545_HUMAN Solute carrier family 25 member 45 (sprot)

A solute carrier family 25 member 45 that is encoded in the genome of human.


PGBD5_HUMAN PiggyBac transposable element-derived protein 5 (sprot)

A piggyBac transposable element-derived protein 5 that is encoded in the genome of human.


transposase activity

Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element.


non-replicative DNA transposition

Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.


LIRB2_HUMAN Leukocyte immunoglobulin-like receptor subfamily B member 2 (sprot)

A leukocyte immunoglobulin-like receptor subfamily B member 2 that is encoded in the genome of human.


MHC class Ib protein complex binding

Binding to a class Ib major histocompatibility complex.


inhibitory MHC class I receptor activity

Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.


negative regulation of antigen processing and presentation

Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.


biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by interleukin-10 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


negative regulation of postsynaptic density organization

Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic density organization.


negative regulation of T cell costimulation

Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.


TXND3_HUMAN Thioredoxin domain-containing protein 3 (sprot)

A thioredoxin domain-containing protein 3 that is encoded in the genome of human.


sperm cytoplasmic droplet

A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce what are called residual bodies. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from 'excessive residual cytoplasm' that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.


GLT16_HUMAN Polypeptide N-acetylgalactosaminyltransferase 16 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 16 that is encoded in the genome of human.


SVOPL_HUMAN Putative transporter SVOPL (sprot)

A putative transporter SVOPL that is encoded in the genome of human.


CPXM2_HUMAN Inactive carboxypeptidase-like protein X2 (sprot)

An inactive carboxypeptidase-like protein X2 that is encoded in the genome of human.


FGRL1_HUMAN Fibroblast growth factor receptor-like 1 (sprot)

A fibroblast growth factor receptor-like 1 that is encoded in the genome of human.


GUF1_HUMAN Translation factor GUF1, mitochondrial (sprot)

A GTP-binding protein GUF1 that is encoded in the genome of human.


RIBC1_HUMAN RIB43A-like with coiled-coils protein 1 (sprot)

A RIB43A-like with coiled-coils protein 1 that is encoded in the genome of human.


ZN843_HUMAN Zinc finger protein 843 (sprot)

A zinc finger protein 843 that is encoded in the genome of human.


LNX2_HUMAN Ligand of Numb protein X 2 (sprot)

A ligand of Numb protein X 2 that is encoded in the genome of human.


LRC18_HUMAN Leucine-rich repeat-containing protein 18 (sprot)

A leucine-rich repeat-containing protein 18 that is encoded in the genome of human.


FXL16_HUMAN F-box/LRR-repeat protein 16 (sprot)

An F-box/LRR-repeat protein 16 that is encoded in the genome of human.


D2HDH_HUMAN D-2-hydroxyglutarate dehydrogenase, mitochondrial (sprot)

A D-2-hydroxyglutarate dehydrogenase, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.


MFD4A_HUMAN Major facilitator superfamily domain-containing protein 4A (sprot)

A major facilitator superfamily domain-containing protein 4A that is encoded in the genome of human.


SFRP1_HUMAN Secreted frizzled-related protein 1 (sprot)

A secreted frizzled-related protein 1 that is encoded in the genome of human.


stromal-epithelial cell signaling involved in prostate gland development

The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development.


convergent extension involved in somitogenesis

The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.


regulation of midbrain dopaminergic neuron differentiation

Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.


negative regulation of planar cell polarity pathway involved in axis elongation

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.


negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.


negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.


FSTL5_HUMAN Follistatin-related protein 5 (sprot)

A follistatin-related protein 5 that is encoded in the genome of human.


LIX1_HUMAN Protein limb expression 1 homolog (sprot)

A protein limb expression 1 that is encoded in the genome of human.


RYBP_HUMAN RING1 and YY1-binding protein (sprot)

A RING1 and YY1-binding protein that is encoded in the genome of human.


PNKD_HUMAN Probable hydrolase PNKD (sprot)

A probable hydrolase PNKD that is encoded in the genome of human.


GALT4_HUMAN Polypeptide N-acetylgalactosaminyltransferase 4 (sprot)

A polypeptide N-acetylgalactosaminyltransferase 4 that is encoded in the genome of human.


SESQ1_HUMAN Sesquipedalian-1 (sprot)

A sesquipedalian-1 that is encoded in the genome of human.


FBX39_HUMAN F-box only protein 39 (sprot)

An F-box only protein 39 that is encoded in the genome of human.


NIN_HUMAN Ninein (sprot)

A ninein that is encoded in the genome of human.


STX19_HUMAN Syntaxin-19 (sprot)

A syntaxin-19 that is encoded in the genome of human.


MINK1_HUMAN Misshapen-like kinase 1 (sprot)

A misshapen-like kinase 1 that is encoded in the genome of human.


CQ078_HUMAN Uncharacterized protein C17orf78 (sprot)

An uncharacterized protein C17orf78 that is encoded in the genome of human.


FTMT_HUMAN Ferritin, mitochondrial (sprot)

A ferritin, mitochondrial that is encoded in the genome of human.


BPIB2_HUMAN BPI fold-containing family B member 2 (sprot)

A BPI fold-containing family B member 2 that is encoded in the genome of human.


S22AO_HUMAN Steroid transmembrane transporter SLC22A24 (sprot)

A steroid transmembrane transporter SLC22A24 that is encoded in the genome of human.


sterol transmembrane transport

The process in which a sterol is transported across a membrane. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


RN175_HUMAN RING finger protein 175 (sprot)

A RING finger protein 175 that is encoded in the genome of human.


ARL14_HUMAN ADP-ribosylation factor-like protein 14 (sprot)

An ADP-ribosylation factor-like protein 14 that is encoded in the genome of human.


SPA6L_HUMAN Spermatogenesis associated 6-like protein (sprot)

A spermatogenesis associated 6-like protein that is encoded in the genome of human.


TOM5_HUMAN Mitochondrial import receptor subunit TOM5 homolog (sprot)

A mitochondrial import receptor subunit TOM5 that is encoded in the genome of human.


CARME_HUMAN Carnosine N-methyltransferase (sprot)

A carnosine N-methyltransferase that is encoded in the genome of human.


carnosine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H+.


carnosine metabolic process

The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).


RPRML_HUMAN Reprimo-like protein (sprot)

A reprimo-like protein that is encoded in the genome of human.


T151A_HUMAN Transmembrane protein 151A (sprot)

A transmembrane protein 151A that is encoded in the genome of human.


PP4P2_HUMAN Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (sprot)

A type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase that is encoded in the genome of human.


SPEM1_HUMAN Spermatid maturation protein 1 (sprot)

A spermatid maturation protein 1 that is encoded in the genome of human.


CCD24_HUMAN Coiled-coil domain-containing protein 24 (sprot)

A coiled-coil domain-containing protein 24 that is encoded in the genome of human.


CTL3_HUMAN Choline transporter-like protein 3 (sprot)

A choline transporter-like protein 3 that is encoded in the genome of human.


KLH36_HUMAN Kelch-like protein 36 (sprot)

A kelch-like protein 36 that is encoded in the genome of human.


KIF2B_HUMAN Kinesin-like protein KIF2B (sprot)

A kinesin-like protein KIF2B that is encoded in the genome of human.


IT70B_HUMAN Intraflagellar transport protein 70B (sprot)

A tetratricopeptide repeat protein 30B that is encoded in the genome of human.


MESH1_HUMAN Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (sprot)

A guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 that is encoded in the genome of human.


PTGR3_HUMAN Prostaglandin reductase 3 (sprot)

A prostaglandin reductase 3 that is encoded in the genome of human.


15-oxoprostaglandin 13-oxidase activity

Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.


MIA40_HUMAN Mitochondrial intermembrane space import and assembly protein 40 (sprot)

A mitochondrial intermembrane space import and assembly protein 40 that is encoded in the genome of human.


PAQR4_HUMAN Progestin and adipoQ receptor family member 4 (sprot)

A progestin and adipoQ receptor family member 4 that is encoded in the genome of human.


MALD2_HUMAN MARVEL domain-containing protein 2 (sprot)

A MARVEL domain-containing protein 2 that is encoded in the genome of human.


CBPA6_HUMAN Carboxypeptidase A6 (sprot)

A carboxypeptidase A6 that is encoded in the genome of human.


ARG39_HUMAN Rho guanine nucleotide exchange factor 39 (sprot)

A Rho guanine nucleotide exchange factor 39 that is encoded in the genome of human.


CBR4_HUMAN 3-oxoacyl-[acyl-carrier-protein] reductase (sprot)

A 3-oxoacyl-[acyl-carrier-protein] reductase that is encoded in the genome of human.


NAD(P)H dehydrogenase (quinone) activity

Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.


T11L2_HUMAN T-complex protein 11-like protein 2 (sprot)

A T-complex protein 11-like protein 2 that is encoded in the genome of human.


muscle cell migration

The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.


EMC5_HUMAN ER membrane protein complex subunit 5 (sprot)

An ER membrane protein complex subunit 5 that is encoded in the genome of human.


cobalt ion transmembrane transporter activity

Enables the transfer of cobalt (Co) ions from one side of a membrane to the other.


SVOP_HUMAN Synaptic vesicle 2-related protein (sprot)

A synaptic vesicle 2-related protein that is encoded in the genome of human.


DJC22_HUMAN DnaJ homolog subfamily C member 22 (sprot)

A DnaJ homolog subfamily C member 22 that is encoded in the genome of human.


ZN808_HUMAN Zinc finger protein 808 (sprot)

A zinc finger protein 808 that is encoded in the genome of human.


AF1L2_HUMAN Actin filament-associated protein 1-like 2 (sprot)

An actin filament-associated protein 1-like 2 that is encoded in the genome of human.


EFC4A_HUMAN EF-hand calcium-binding domain-containing protein 4A (sprot)

An EF-hand calcium-binding domain-containing protein 4A that is encoded in the genome of human.


TM199_HUMAN Transmembrane protein 199 (sprot)

A transmembrane protein 199 that is encoded in the genome of human.


FBXL6_HUMAN F-box/LRR-repeat protein 6 (sprot)

An F-box/LRR-repeat protein 6 that is encoded in the genome of human.


FBCD1_HUMAN Fibrinogen C domain-containing protein 1 (sprot)

A fibrinogen C domain-containing protein 1 that is encoded in the genome of human.


OGFD1_HUMAN Prolyl 3-hydroxylase OGFOD1 (sprot)

A prolyl 3-hydroxylase OGFOD1 that is encoded in the genome of human.


peptidyl-proline dioxygenase activity

Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.


peptidyl-proline 3-dioxygenase activity

Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.


ZN276_HUMAN Zinc finger protein 276 (sprot)

A zinc finger protein 276 that is encoded in the genome of human.


AFAP1_HUMAN Actin filament-associated protein 1 (sprot)

An actin filament-associated protein 1 that is encoded in the genome of human.


MREG_HUMAN Melanoregulin (sprot)

A melanoregulin that is encoded in the genome of human.


ZCHC9_HUMAN Zinc finger CCHC domain-containing protein 9 (sprot)

A zinc finger CCHC domain-containing protein 9 that is encoded in the genome of human.


DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 (sprot)

A serine/threonine-protein kinase DCLK2 that is encoded in the genome of human.


OXR1_HUMAN Oxidation resistance protein 1 (sprot)

An oxidation resistance protein 1 that is encoded in the genome of human.


ZN561_HUMAN Zinc finger protein 561 (sprot)

A zinc finger protein 561 that is encoded in the genome of human.


MPND_HUMAN MPN domain-containing protein (sprot)

An MPN domain-containing protein that is encoded in the genome of human.


ZGPAT_HUMAN Zinc finger CCCH-type with G patch domain-containing protein (sprot)

A zinc finger CCCH-type with G patch domain-containing protein that is encoded in the genome of human.


CERS5_HUMAN Ceramide synthase 5 (sprot)

A ceramide synthase 5 that is encoded in the genome of human.


CAHM5_HUMAN Calcium homeostasis modulator protein 5 (sprot)

A calcium homeostasis modulator protein 5 that is encoded in the genome of human.


SRBD1_HUMAN S1 RNA-binding domain-containing protein 1 (sprot)

An S1 RNA-binding domain-containing protein 1 that is encoded in the genome of human.


DTWD1_HUMAN tRNA-uridine aminocarboxypropyltransferase 1 (sprot)

A tRNA-uridine aminocarboxypropyltransferase 1 that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine.


TAB3_HUMAN TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (sprot)

A TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 that is a translation product of the TAB3 that is encoded in the genome of human.


WDTC1_HUMAN WD and tetratricopeptide repeats protein 1 (sprot)

A WD and tetratricopeptide repeats protein 1 that is encoded in the genome of human.


intracellular chemical homeostasis

A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell.


GBGT1_HUMAN Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (sprot)

A globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 that is encoded in the genome of human.


NKAP_HUMAN NF-kappa-B-activating protein (sprot)

An NF-kappa-B-activating protein that is encoded in the genome of human.


SIM20_HUMAN Small integral membrane protein 20 (sprot)

A small integral membrane protein 20 that is encoded in the genome of human.


MACOI_HUMAN Macoilin (sprot)

A macoilin that is encoded in the genome of human.


LRA25_HUMAN Leucine repeat adapter protein 25 (sprot)

A leucine repeat adapter protein 25 that is encoded in the genome of human.


SH2D3_HUMAN SH2 domain-containing protein 3C (sprot)

An SH2 domain-containing protein 3C that is encoded in the genome of human.


ARRD1_HUMAN Arrestin domain-containing protein 1 (sprot)

An arrestin domain-containing protein 1 that is encoded in the genome of human.


extracellular vesicle biogenesis

The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content.


KCNRG_HUMAN Potassium channel regulatory protein (sprot)

A potassium channel regulatory protein that is encoded in the genome of human.


DHRSX_HUMAN Dehydrogenase/reductase SDR family member on chromosome X (sprot)

A dehydrogenase/reductase SDR family member on chromosome X that is encoded in the genome of human.


NOPC1_HUMAN NOP protein chaperone 1 (sprot)

A NOP protein chaperone 1 that is encoded in the genome of human.


box C/D snoRNP complex binding

Binding to a box C/D snoRNP complex.


MINY1_HUMAN Ubiquitin carboxyl-terminal hydrolase MINDY-1 (sprot)

A ubiquitin carboxyl-terminal hydrolase MINDY-1 that is encoded in the genome of human.


cysteine-type carboxypeptidase activity

Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


SPIC_HUMAN Transcription factor Spi-C (sprot)

A transcription factor Spi-C that is encoded in the genome of human.


CISD2_HUMAN CDGSH iron-sulfur domain-containing protein 2 (sprot)

A CDGSH iron-sulfur domain-containing protein 2 that is encoded in the genome of human.


RP25L_HUMAN Ribonuclease P protein subunit p25-like protein (sprot)

A ribonuclease P protein subunit p25-like protein that is encoded in the genome of human.


ATPF2_HUMAN ATP synthase mitochondrial F1 complex assembly factor 2 (sprot)

An ATP synthase mitochondrial F1 complex assembly factor 2 that is encoded in the genome of human.


proton-transporting ATP synthase complex assembly

The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.


TTC9C_HUMAN Tetratricopeptide repeat protein 9C (sprot)

A tetratricopeptide repeat protein 9C that is encoded in the genome of human.


JAGN1_HUMAN Protein jagunal homolog 1 (sprot)

A protein jagunal homolog 1 that is encoded in the genome of human.


RM50_HUMAN Large ribosomal subunit protein mL50 (sprot)

A 39S ribosomal protein L50, mitochondrial that is encoded in the genome of human.


ZC3H8_HUMAN Zinc finger CCCH domain-containing protein 8 (sprot)

A zinc finger CCCH domain-containing protein 8 that is encoded in the genome of human.


CCD33_HUMAN Coiled-coil domain-containing protein 33 (sprot)

A coiled-coil domain-containing protein 33 that is encoded in the genome of human.


S2541_HUMAN Mitochondrial carrier protein SCaMC-3L (sprot)

A mitochondrial carrier protein SCaMC-3L that is encoded in the genome of human.


KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase kinase 1 (sprot)

A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of human.


TBC19_HUMAN TBC1 domain family member 19 (sprot)

A TBC1 domain family member 19 that is encoded in the genome of human.


RNF10_HUMAN E3 ubiquitin-protein ligase RNF10 (sprot)

A RING finger protein 10 that is encoded in the genome of human.


NGEF_HUMAN Ephexin-1 (sprot)

An ephexin-1 that is encoded in the genome of human.


FA24B_HUMAN Protein FAM24B (sprot)

A protein FAM24B that is encoded in the genome of human.


RFLB_HUMAN Refilin-B (sprot)

A refilin-B that is encoded in the genome of human.


IF4E3_HUMAN Eukaryotic translation initiation factor 4E type 3 (sprot)

A eukaryotic translation initiation factor 4E type 3 that is encoded in the genome of human.


MS3L1_HUMAN Male-specific lethal 3 homolog (sprot)

A male-specific lethal 3 that is encoded in the genome of human.


PAR16_HUMAN Protein mono-ADP-ribosyltransferase PARP16 (sprot)

A protein mono-ADP-ribosyltransferase PARP16 that is encoded in the genome of human.


AADAT_HUMAN Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (sprot)

A kynurenine/alpha-aminoadipate aminotransferase, mitochondrial that is encoded in the genome of human.


2-aminoadipate transaminase activity

Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.


Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate.


Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.


KCD17_HUMAN BTB/POZ domain-containing protein KCTD17 (sprot)

A BTB/POZ domain-containing protein KCTD17 that is encoded in the genome of human.


DPP10_HUMAN Inactive dipeptidyl peptidase 10 (sprot)

An inactive dipeptidyl peptidase 10 that is encoded in the genome of human.


TR1L1_HUMAN Translocating chain-associated membrane protein 1-like 1 (sprot)

A translocation-associated membrane protein 1-like 1 that is encoded in the genome of human.


FHI1B_HUMAN FHF complex subunit HOOK-interacting protein 1B (sprot)

An FHF complex subunit HOOK interacting protein 1B that is encoded in the genome of human.


TM156_HUMAN Transmembrane protein 156 (sprot)

A transmembrane protein 156 that is encoded in the genome of human.


OR2C3_HUMAN Olfactory receptor 2C3 (sprot)

An olfactory receptor 2C3 that is encoded in the genome of human.


MEIOB_HUMAN Meiosis-specific with OB domain-containing protein (sprot)

A meiosis-specific with OB domain-containing protein that is encoded in the genome of human.


single-stranded DNA 3'-5' DNA exonuclease activity

Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.


LZTR1_HUMAN Leucine-zipper-like transcriptional regulator 1 (sprot)

A leucine-zipper-like transcriptional regulator 1 that is encoded in the genome of human.


NBPFF_HUMAN Neuroblastoma breakpoint family member 15 (sprot)

A neuroblastoma breakpoint family member 15 that is encoded in the genome of human.


TM86B_HUMAN Lysoplasmalogenase (sprot)

A lysoplasmalogenase that is encoded in the genome of human.


ether hydrolase activity

Catalysis of the hydrolysis of an ether bond, -O-.


Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde.


COMD1_HUMAN COMM domain-containing protein 1 (sprot)

A COMM domain-containing protein 1 that is encoded in the genome of human.


ZBTB2_HUMAN Zinc finger and BTB domain-containing protein 2 (sprot)

A zinc finger and BTB domain-containing protein 2 that is encoded in the genome of human.


DRAM1_HUMAN DNA damage-regulated autophagy modulator protein 1 (sprot)

A damage-regulated autophagy modulator that is encoded in the genome of human.


CPSF7_HUMAN Cleavage and polyadenylation specificity factor subunit 7 (sprot)

A cleavage and polyadenylation specificity factor subunit 7 that is encoded in the genome of human.


DB125_HUMAN Beta-defensin 125 (sprot)

A beta-defensin 125 that is encoded in the genome of human.


DB123_HUMAN Beta-defensin 123 (sprot)

A beta-defensin 123 that is encoded in the genome of human.


DB119_HUMAN Beta-defensin 119 (sprot)

A beta-defensin 119 that is encoded in the genome of human.


ESX1_HUMAN Homeobox protein ESX1 (sprot)

A homeobox protein ESX1 that is encoded in the genome of human.


SC5A8_HUMAN Sodium-coupled monocarboxylate transporter 1 (sprot)

A sodium-coupled monocarboxylate transporter 1 that is encoded in the genome of human.


propionate transmembrane transporter activity

Enables the transfer of propionate from one side of a membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.


passive transmembrane transporter activity

Enables the transfer of a single solute from one side of a membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.


acetate transport

The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


pyruvate transport

The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


propanoate transmembrane transport

The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


nicotinate transport

The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


S15A4_HUMAN Solute carrier family 15 member 4 (sprot)

A solute carrier family 15 member 4 that is encoded in the genome of human.


mast cell homeostasis

The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


L-histidine transmembrane export from vacuole

The directed movement of L-histidine out of the vacuole, across the vacuolar membrane.


MYCT1_HUMAN Myc target protein 1 (sprot)

A Myc target protein 1 that is encoded in the genome of human.


IGSF1_HUMAN Immunoglobulin superfamily member 1 (sprot)

An immunoglobulin superfamily member 1 that is encoded in the genome of human.


LIRA3_HUMAN Leukocyte immunoglobulin-like receptor subfamily A member 3 (sprot)

A leukocyte immunoglobulin-like receptor subfamily A member 3 that is encoded in the genome of human.


RN182_HUMAN E3 ubiquitin-protein ligase RNF182 (sprot)

An E3 ubiquitin-protein ligase RNF182 that is encoded in the genome of human.


ANR29_HUMAN Ankyrin repeat domain-containing protein 29 (sprot)

An ankyrin repeat domain-containing protein 29 that is encoded in the genome of human.


CLD19_HUMAN Claudin-19 (sprot)

A claudin-19 that is encoded in the genome of human.


GCSAM_HUMAN Germinal center-associated signaling and motility protein (sprot)

A germinal center-associated signaling and motility protein that is encoded in the genome of human.


MET27_HUMAN Methyltransferase-like protein 27 (sprot)

A methyltransferase-like protein 27 that is encoded in the genome of human.


CGAT2_HUMAN Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (sprot)

A chondroitin sulfate N-acetylgalactosaminyltransferase 2 that is encoded in the genome of human.


Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP.


dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.


chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.


ATL1_HUMAN ADAMTS-like protein 1 (sprot)

An ADAMTS-like protein 1 that is encoded in the genome of human.


ARFG2_HUMAN ADP-ribosylation factor GTPase-activating protein 2 (sprot)

An ADP-ribosylation factor GTPase-activating protein 2 that is encoded in the genome of human.


EID2_HUMAN EP300-interacting inhibitor of differentiation 2 (sprot)

An EP300-interacting inhibitor of differentiation 2 that is encoded in the genome of human.


LYSET_HUMAN Lysosomal enzyme trafficking factor (sprot)

A lysosomal enzyme trafficking factor that is encoded in the genome of human.


TEX29_HUMAN Testis-expressed protein 29 (sprot)

A testis-expressed protein 29 that is encoded in the genome of human.


SAMD3_HUMAN Sterile alpha motif domain-containing protein 3 (sprot)

A sterile alpha motif domain-containing protein 3 that is encoded in the genome of human.


KASH5_HUMAN Protein KASH5 (sprot)

A coiled-coil domain-containing protein 155 that is encoded in the genome of human.


KTAP2_HUMAN Keratinocyte-associated protein 2 (sprot)

A keratinocyte-associated protein 2 that is encoded in the genome of human.


protein N-linked glycosylation via arginine

The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine.


TM252_HUMAN Transmembrane protein 252 (sprot)

A transmembrane protein 252 that is encoded in the genome of human.


OTU6B_HUMAN Deubiquitinase OTUD6B (sprot)

A deubiquitinase OTUD6B that is encoded in the genome of human.


FITM2_HUMAN Acyl-coenzyme A diphosphatase FITM2 (sprot)

An acyl-coenzyme A diphosphatase FITM2 that is encoded in the genome of human.


fatty-acyl-CoA catabolic process

The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.


ALLC_HUMAN Probable inactive allantoicase (sprot)

An allantoicase that is encoded in the genome of human.


allantoicase activity

Catalysis of the reaction: allantoate + H2O = (S)-ureidoglycolate + urea.


allantoin catabolic process

The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.


AMPO_HUMAN Aminopeptidase O (sprot)

An aminopeptidase O that is encoded in the genome of human.


IQCF1_HUMAN IQ domain-containing protein F1 (sprot)

An IQ domain-containing protein F1 that is encoded in the genome of human.


ZFN2A_HUMAN AN1-type zinc finger protein 2A (sprot)

An AN1-type zinc finger protein 2A that is encoded in the genome of human.


TTC9B_HUMAN Tetratricopeptide repeat protein 9B (sprot)

A tetratricopeptide repeat protein 9B that is encoded in the genome of human.


CA052_HUMAN UPF0690 protein C1orf52 (sprot)

A UPF0690 protein C1orf52 that is encoded in the genome of human.


NATD1_HUMAN Protein NATD1 (sprot)

A protein NATD1 that is encoded in the genome of human.


ACBD7_HUMAN Acyl-CoA-binding domain-containing protein 7 (sprot)

An acyl-CoA-binding domain-containing protein 7 that is encoded in the genome of human.


I22R1_HUMAN Interleukin-22 receptor subunit alpha-1 (sprot)

An interleukin-22 receptor subunit alpha-1 that is encoded in the genome of human.


interferon receptor activity

Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


interleukin-20 binding

Binding to interleukin-20.


interleukin-22 receptor activity

Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


TMC5A_HUMAN Transmembrane and coiled-coil domain-containing protein 5A (sprot)

A transmembrane and coiled-coil domain-containing protein 5A that is encoded in the genome of human.


CD177_HUMAN CD177 antigen (sprot)

A CD177 molecule that is encoded in the genome of human.


MET25_HUMAN Probable methyltransferase-like protein 25 (sprot)

A probable methyltransferase-like protein 25 that is encoded in the genome of human.


EFNMT_HUMAN eEF1A lysine and N-terminal methyltransferase (sprot)

An eEF1A lysine and N-terminal methyltransferase that is encoded in the genome of human.


SERP2_HUMAN Stress-associated endoplasmic reticulum protein 2 (sprot)

A stress-associated endoplasmic reticulum protein 2 that is encoded in the genome of human.


AN13C_HUMAN Ankyrin repeat domain-containing protein 13C (sprot)

An ankyrin repeat domain-containing protein 13C that is encoded in the genome of human.


regulation of anoikis

Any process that modulates the frequency, rate or extent of anoikis.


AR6P6_HUMAN ADP-ribosylation factor-like protein 6-interacting protein 6 (sprot)

An ADP-ribosylation factor-like protein 6-interacting protein 6 that is encoded in the genome of human.


TO6BL_HUMAN Type 2 DNA topoisomerase 6 subunit B-like (sprot)

A type 2 DNA topoisomerase 6 subunit B-like that is encoded in the genome of human.


ARFG1_HUMAN ADP-ribosylation factor GTPase-activating protein 1 (sprot)

An ADP-ribosylation factor GTPase-activating protein 1 that is encoded in the genome of human.


SIR6_HUMAN NAD-dependent protein deacylase sirtuin-6 (sprot)

An NAD-dependent protein deacylase sirtuin-6 that is encoded in the genome of human.


NAD-dependent histone H3K9 deacetylase activity

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.


NAD-dependent histone H3K18 deacetylase activity

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein.


NAD-dependent histone H3K56 deacetylase activity

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 56) + H2O = histone H3 L-lysine (position 56) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 56 of the histone H3 protein.


ketone biosynthetic process

The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.


GP161_HUMAN G-protein coupled receptor 161 (sprot)

A G-protein coupled receptor 161 that is encoded in the genome of human.


negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.


TEX9_HUMAN Testis-expressed protein 9 (sprot)

A testis-expressed protein 9 that is encoded in the genome of human.


CELF5_HUMAN CUGBP Elav-like family member 5 (sprot)

A CUGBP Elav-like family member 5 that is encoded in the genome of human.


USBP1_HUMAN Harmonin-binding protein USHBP1 (sprot)

A harmonin-binding protein USHBP1 that is encoded in the genome of human.


PCD20_HUMAN Protocadherin-20 (sprot)

A protocadherin-20 that is encoded in the genome of human.


LRC17_HUMAN Leucine-rich repeat-containing protein 17 (sprot)

A leucine-rich repeat-containing protein 17 that is encoded in the genome of human.


CC185_HUMAN Coiled-coil domain-containing protein 185 (sprot)

A protein that is a translation product of the CCDC185 gene in human.


ZN655_HUMAN Zinc finger protein 655 (sprot)

A zinc finger protein 655 that is encoded in the genome of human.


NPW_HUMAN Neuropeptide W (sprot)

A neuropeptide W that is encoded in the genome of human.


KI3L3_HUMAN Killer cell immunoglobulin-like receptor 3DL3 (sprot)

A killer cell immunoglobulin-like receptor 3DL3 that is encoded in the genome of human.


KC1AL_HUMAN Casein kinase I isoform alpha-like (sprot)

A casein kinase I isoform alpha-like that is encoded in the genome of human.


S66A3_HUMAN Solute carrier family 66 member 3 (sprot)

A solute carrier family 66 member 3 that is encoded in the genome of human.


EMC1_HUMAN ER membrane protein complex subunit 1 (sprot)

An ER membrane protein complex subunit 1 that is encoded in the genome of human.


ZN525_HUMAN Zinc finger protein 525 (sprot)

A zinc finger protein 525 that is encoded in the genome of human.


KLDC1_HUMAN Kelch domain-containing protein 1 (sprot)

A kelch domain-containing protein 1 that is encoded in the genome of human.


HORM2_HUMAN HORMA domain-containing protein 2 (sprot)

A HORMA domain-containing protein 2 that is encoded in the genome of human.


PACRL_HUMAN PACRG-like protein (sprot)

A PACRG-like protein that is encoded in the genome of human.


EFCB3_HUMAN EF-hand calcium-binding domain-containing protein 3 (sprot)

An EF-hand calcium-binding domain-containing protein 3 that is encoded in the genome of human.


LRC52_HUMAN Leucine-rich repeat-containing protein 52 (sprot)

A leucine-rich repeat-containing protein 52 that is encoded in the genome of human.


TRIMM_HUMAN Probable E3 ubiquitin-protein ligase TRIML2 (sprot)

A probable E3 ubiquitin-protein ligase TRIML2 that is encoded in the genome of human.


TM217_HUMAN Transmembrane protein 217 (sprot)

A transmembrane protein 217 that is encoded in the genome of human.


RN148_HUMAN RING finger protein 148 (sprot)

A RING finger protein 148 that is encoded in the genome of human.


CBLL2_HUMAN E3 ubiquitin-protein ligase CBLL2 (sprot)

An E3 ubiquitin-protein ligase CBLL2 that is encoded in the genome of human.


UBL4B_HUMAN Ubiquitin-like protein 4B (sprot)

A ubiquitin-like protein 4B that is encoded in the genome of human.


PO5F2_HUMAN POU domain, class 5, transcription factor 2 (sprot)

A POU domain, class 5, transcription factor 2 that is encoded in the genome of human.


PAF1_HUMAN RNA polymerase II-associated factor 1 homolog (sprot)

An RNA polymerase II-associated factor 1 that is encoded in the genome of human.


AMER2_HUMAN APC membrane recruitment protein 2 (sprot)

An APC membrane recruitment protein 2 that is encoded in the genome of human.


ZN433_HUMAN Zinc finger protein 433 (sprot)

A zinc finger protein 433 that is encoded in the genome of human.


DYLT5_HUMAN Dynein light chain Tctex-type 5 (sprot)

A dynein light chain Tctex-type 5 that is encoded in the genome of human.


ZN283_HUMAN Zinc finger protein 283 (sprot)

A zinc finger protein 283 that is encoded in the genome of human.


F86B1_HUMAN Putative protein N-methyltransferase FAM86B1 (sprot)

A putative protein N-methyltransferase FAM86B1 that is encoded in the genome of human.


PLD5_HUMAN Inactive phospholipase D5 (sprot)

An inactive phospholipase D5 that is encoded in the genome of human.


CLD22_HUMAN Claudin-22 (sprot)

A claudin-22 that is encoded in the genome of human.


CEAS1_HUMAN Putative uncharacterized protein CELF2-AS1 (sprot)


ZN676_HUMAN Zinc finger protein 676 (sprot)

A zinc finger protein 676 that is encoded in the genome of human.


NANG2_HUMAN Putative homeobox protein NANOG2 (sprot)


CCYL1_HUMAN Cyclin-Y-like protein 1 (sprot)

A cyclin-Y-like protein 1 that is encoded in the genome of human.


DNJ5G_HUMAN DnaJ homolog subfamily C member 5G (sprot)

A DnaJ homolog subfamily C member 5G that is encoded in the genome of human.


ARI2O_HUMAN Uncharacterized protein ARIH2OS (sprot)

A protein that is a translation product of the ARIH2OS gene in human.


EFHB_HUMAN EF-hand domain-containing family member B (sprot)

An EF-hand domain-containing family member B that is encoded in the genome of human.


TPRX1_HUMAN Tetra-peptide repeat homeobox protein 1 (sprot)

A tetra-peptide repeat homeobox protein 1 that is encoded in the genome of human.


BEND7_HUMAN BEN domain-containing protein 7 (sprot)

A BEN domain-containing protein 7 that is encoded in the genome of human.


ADGB_HUMAN Androglobin (sprot)

An androglobin that is encoded in the genome of human.


MAGB6_HUMAN Melanoma-associated antigen B6 (sprot)

A melanoma-associated antigen B6 that is encoded in the genome of human.


SIGL1_HUMAN SIGLEC family-like protein 1 (sprot)

A SIGLEC family-like protein 1 that is encoded in the genome of human.


KIAS3_HUMAN Putative uncharacterized protein KIRREL3-AS3 (sprot)

A proline-rich protein 10 that is encoded in the genome of human.


ANR31_HUMAN Ankyrin repeat domain-containing protein 31 (sprot)

An ankyrin repeat domain-containing protein 31 that is encoded in the genome of human.


meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


positive regulation of meiotic DNA double-strand break formation

Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation.


STPG4_HUMAN Protein STPG4 (sprot)

A protein STPG4 that is encoded in the genome of human.


UBR7_HUMAN Putative E3 ubiquitin-protein ligase UBR7 (sprot)

A putative E3 ubiquitin-protein ligase UBR7 that is encoded in the genome of human.


PDILT_HUMAN Protein disulfide-isomerase-like protein of the testis (sprot)

A protein disulfide-isomerase-like protein of the testis that is encoded in the genome of human.


S35G3_HUMAN Solute carrier family 35 member G3 (sprot)

A solute carrier family 35 member G3 that is encoded in the genome of human.


PR23E_HUMAN Proline-rich protein 23E (sprot)

A protein that is a translation product of the C3orf56 gene in human.


CNTD1_HUMAN Cyclin N-terminal domain-containing protein 1 (sprot)

A cyclin N-terminal domain-containing protein 1 that is encoded in the genome of human.


TMM99_HUMAN Uncharacterized protein KRT10-AS1 (sprot)

An uncharacterized protein KRT10-AS1 that is encoded in the genome of human.


PPM1N_HUMAN Probable protein phosphatase 1N (sprot)

A probable protein phosphatase 1N that is encoded in the genome of human.


ZN611_HUMAN Zinc finger protein 611 (sprot)

A zinc finger protein 611 that is encoded in the genome of human.


TSYL6_HUMAN Testis-specific Y-encoded-like protein 6 (sprot)

A testis-specific Y-encoded-like protein 6 that is encoded in the genome of human.


TTLL6_HUMAN Tubulin polyglutamylase TTLL6 (sprot)

A tubulin polyglutamylase TTLL6 that is encoded in the genome of human.


positive regulation of cilium movement

Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.


regulation of cilium beat frequency involved in ciliary motility

Any process that modulates the frequency of cilium beating involved in ciliary motility.


ZN713_HUMAN Zinc finger protein 713 (sprot)

A zinc finger protein 713 that is encoded in the genome of human.


CG031_HUMAN Uncharacterized protein C7orf31 (sprot)

An uncharacterized protein C7orf31 that is encoded in the genome of human.


FRMD1_HUMAN FERM domain-containing protein 1 (sprot)

A FERM domain-containing protein 1 that is encoded in the genome of human.


ZN614_HUMAN Zinc finger protein 614 (sprot)

A zinc finger protein 614 that is encoded in the genome of human.


CGAS_HUMAN Cyclic GMP-AMP synthase (sprot)

A protein MB21D1 that is encoded in the genome of human.


2',3'-cyclic GMP-AMP synthase activity

Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(2'-5')A-P(3'-5') (cyclic 2',3' GAMP).


ZN366_HUMAN Zinc finger protein 366 (sprot)

A zinc finger protein 366 that is encoded in the genome of human.


ANR44_HUMAN Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (sprot)

A serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B that is encoded in the genome of human.


DDX51_HUMAN ATP-dependent RNA helicase DDX51 (sprot)

An ATP-dependent RNA helicase DDX51 that is encoded in the genome of human.


TEANC_HUMAN Transcription elongation factor A N-terminal and central domain-containing protein (sprot)

A transcription elongation factor A N-terminal and central domain-containing protein that is encoded in the genome of human.


ZN781_HUMAN Zinc finger protein 781 (sprot)

A zinc finger protein 781 that is encoded in the genome of human.


PDCD7_HUMAN Programmed cell death protein 7 (sprot)

A programmed cell death protein 7 that is encoded in the genome of human.


NKAI3_HUMAN Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 (sprot)

A sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 that is encoded in the genome of human.


IRAS1_HUMAN Uncharacterized protein IRF1-AS1 (sprot)

A protein that is a translation product of the IRF1-AS1 gene in human.


ZN513_HUMAN Zinc finger protein 513 (sprot)

A zinc finger protein 513 that is encoded in the genome of human.


CE112_HUMAN Centrosomal protein of 112 kDa (sprot)

A centrosomal protein of 112 kDa that is encoded in the genome of human.


YIPF7_HUMAN Protein YIPF7 (sprot)

A protein YIPF7 that is encoded in the genome of human.


LSME1_HUMAN Leucine-rich single-pass membrane protein 1 (sprot)

A leucine-rich single-pass membrane protein 1 that is encoded in the genome of human.


VGLL2_HUMAN Transcription cofactor vestigial-like protein 2 (sprot)

A transcription cofactor vestigial-like protein 2 that is encoded in the genome of human.


SAM12_HUMAN Sterile alpha motif domain-containing protein 12 (sprot)

A sterile alpha motif domain-containing protein 12 that is encoded in the genome of human.


CQ055_HUMAN Putative uncharacterized protein encoded by LINC00482 (sprot)

A putative uncharacterized protein encoded by LINC00482 that is encoded in the genome of human.


ZN615_HUMAN Zinc finger protein 615 (sprot)

A zinc finger protein 615 that is encoded in the genome of human.


F241A_HUMAN Uncharacterized protein FAM241A (sprot)

An uncharacterized protein FAM241A that is encoded in the genome of human.


K1958_HUMAN Uncharacterized protein KIAA1958 (sprot)

An uncharacterized protein KIAA1958 that is encoded in the genome of human.


ZN491_HUMAN Zinc finger protein 491 (sprot)

A zinc finger protein 491 that is encoded in the genome of human.


ARL10_HUMAN ADP-ribosylation factor-like protein 10 (sprot)

An ADP-ribosylation factor-like protein 10 that is encoded in the genome of human.


NAT16_HUMAN Probable N-acetyltransferase 16 (sprot)

A probable N-acetyltransferase 16 that is encoded in the genome of human.


RN152_HUMAN E3 ubiquitin-protein ligase RNF152 (sprot)

An E3 ubiquitin-protein ligase RNF152 that is encoded in the genome of human.


PTGR2_HUMAN Prostaglandin reductase 2 (sprot)

A prostaglandin reductase 2 that is encoded in the genome of human.


C56D1_HUMAN Probable transmembrane reductase CYB561D1 (sprot)

A probable transmembrane reductase CYB561D1 that is encoded in the genome of human.


ENDOV_HUMAN Endonuclease V (sprot)

An endonuclease V that is encoded in the genome of human.


endodeoxyribonuclease activity, producing 5'-phosphomonoesters

Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.


RNA endonuclease activity, producing 5'-phosphomonoesters

Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.


COX18_HUMAN Cytochrome c oxidase assembly protein COX18, mitochondrial (sprot)

A cytochrome c oxidase assembly protein COX18, mitochondrial that is encoded in the genome of human.


protein insertion into mitochondrial inner membrane from matrix

The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.


protein insertion into mitochondrial membrane

The process that results in the incorporation of a protein into a mitochondrial membrane.


NIPA2_HUMAN Magnesium transporter NIPA2 (sprot)

A magnesium transporter NIPA2 that is encoded in the genome of human.


S2529_HUMAN Mitochondrial basic amino acids transporter (sprot)

A mitochondrial basic amino acids transporter that is encoded in the genome of human.


high-affinity L-arginine transmembrane transporter activity

Enables the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


high-affinity lysine transmembrane transporter activity

Enables the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


L-histidine transmembrane transport

The directed movement of L-histidine across a membrane.


mitochondrial L-ornithine transmembrane transport

The process in which L-ornithine is transported across a mitochondrial membrane, into or out of the mitochondrion.


CB069_HUMAN Mitochondrial protein C2orf69 (sprot)

A mitochondrial protein C2orf69 that is encoded in the genome of human.


AL14E_HUMAN ARL14 effector protein (sprot)

An ARL14 effector protein that is encoded in the genome of human.


ENAH_HUMAN Protein enabled homolog (sprot)

A protein enabled that is encoded in the genome of human.


CDYL2_HUMAN Chromodomain Y-like protein 2 (sprot)

A chromodomain Y-like protein 2 that is encoded in the genome of human.


RTL3_HUMAN Retrotransposon Gag-like protein 3 (sprot)

A retrotransposon Gag-like protein 3 that is encoded in the genome of human.


BMPER_HUMAN BMP-binding endothelial regulator protein (sprot)

A BMP-binding endothelial regulator protein that is encoded in the genome of human.


GBP7_HUMAN Guanylate-binding protein 7 (sprot)

A guanylate-binding protein 7 that is encoded in the genome of human.


negative regulation of type III interferon production

Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


ANS4B_HUMAN Ankyrin repeat and SAM domain-containing protein 4B (sprot)

An ankyrin repeat and SAM domain-containing protein 4B that is encoded in the genome of human.


protein localization to microvillus

A process in which a protein is transported to, or maintained in, a location within a microvillus.


TM105_HUMAN Transmembrane protein 105 (sprot)

A transmembrane protein 105 that is encoded in the genome of human.


PLPL1_HUMAN Omega-hydroxyceramide transacylase (sprot)

An omega-hydroxyceramide transacylase that is encoded in the genome of human.


Catalysis of the reaction: 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + N-(30-hydroxytriacontanoyl)-sphing-4-enine = di-(9Z,12Z)-octadecadienoylglycerol + N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine.


The chemical reactions and pathways resulting in the formation of omega-hydroxyceramide/acylceramide.


MB213_HUMAN Protein mab-21-like 3 (sprot)

A protein mab-21-like 3 that is encoded in the genome of human.


VA0D2_HUMAN V-type proton ATPase subunit d 2 (sprot)

A V-type proton ATPase subunit d 2 that is encoded in the genome of human.


ZFP41_HUMAN Zinc finger protein 41 homolog (sprot)

A zinc finger protein 41 homolog that is encoded in the genome of human.


DCBD1_HUMAN Discoidin, CUB and LCCL domain-containing protein 1 (sprot)

A discoidin, CUB and LCCL domain-containing protein 1 that is encoded in the genome of human.


ZN441_HUMAN Zinc finger protein 441 (sprot)

A zinc finger protein 441 that is encoded in the genome of human.


DAND5_HUMAN DAN domain family member 5 (sprot)

A DAN domain family member 5 that is encoded in the genome of human.


sequestering of nodal from receptor via nodal binding

Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.


NRAC_HUMAN Nutritionally-regulated adipose and cardiac enriched protein homolog (sprot)

A nutritionally-regulated adipose and cardiac enriched protein homolog that is encoded in the genome of human.


AMER3_HUMAN APC membrane recruitment protein 3 (sprot)

An APC membrane recruitment protein 3 that is encoded in the genome of human.


PRLD2_HUMAN PRELI domain-containing protein 2 (sprot)

A PRELI domain-containing protein 2 that is encoded in the genome of human.


GPT11_HUMAN G patch domain-containing protein 11 (sprot)

A G patch domain-containing protein 11 that is encoded in the genome of human.


CE120_HUMAN Centrosomal protein of 120 kDa (sprot)

A centrosomal protein of 120 kDa that is encoded in the genome of human.


ABTB2_HUMAN Ankyrin repeat and BTB/POZ domain-containing protein 2 (sprot)

An ankyrin repeat and BTB/POZ domain-containing protein 2 that is encoded in the genome of human.


ZDH22_HUMAN Palmitoyltransferase ZDHHC22 (sprot)

A palmitoyltransferase ZDHHC22 that is encoded in the genome of human.


LRTM2_HUMAN Leucine-rich repeat and transmembrane domain-containing protein 2 (sprot)

A leucine-rich repeat and transmembrane domain-containing protein 2 that is encoded in the genome of human.


ZN709_HUMAN Zinc finger protein 709 (sprot)

A zinc finger protein 709 that is encoded in the genome of human.


RM43_HUMAN Large ribosomal subunit protein mL43 (sprot)

A 39S ribosomal protein L43, mitochondrial that is encoded in the genome of human.


NECA1_HUMAN N-terminal EF-hand calcium-binding protein 1 (sprot)

An N-terminal EF-hand calcium-binding protein 1 that is encoded in the genome of human.


ZN557_HUMAN Zinc finger protein 557 (sprot)

A zinc finger protein 557 that is encoded in the genome of human.


CCD89_HUMAN Coiled-coil domain-containing protein 89 (sprot)

A coiled-coil domain-containing protein 89 that is encoded in the genome of human.


RLIG1_HUMAN RNA ligase 1 (sprot)

An uncharacterized protein C12orf29 that is encoded in the genome of human.


RNA ligase (ATP) activity

Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m).


protein adenylylation

The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid.


NEPR1_HUMAN Nuclear envelope phosphatase-regulatory subunit 1 (sprot)

A nuclear envelope phosphatase-regulatory subunit 1 that is encoded in the genome of human.


JMY_HUMAN Junction-mediating and -regulatory protein (sprot)

A junction-mediating and -regulatory protein that is encoded in the genome of human.


'de novo' actin filament nucleation

The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.


RGF1A_HUMAN Ras-GEF domain-containing family member 1A (sprot)

A Ras-GEF domain-containing family member 1A that is encoded in the genome of human.


F133A_HUMAN Protein FAM133A (sprot)

A protein FAM133A that is encoded in the genome of human.


NAT8L_HUMAN N-acetylaspartate synthetase (sprot)

An N-acetylaspartate synthetase that is encoded in the genome of human.


aspartate N-acetyltransferase activity

Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H+.


GDPD1_HUMAN Lysophospholipase D GDPD1 (sprot)

A lysophospholipase D GDPD1 that is encoded in the genome of human.


ZN454_HUMAN Zinc finger protein 454 (sprot)

A zinc finger protein 454 that is encoded in the genome of human.


MUT7_HUMAN Exonuclease mut-7 homolog (sprot)

An exonuclease mut-7 homolog that is encoded in the genome of human.


SYT2_HUMAN Synaptotagmin-2 (sprot)

A synaptotagmin-2 that is encoded in the genome of human.


FADS6_HUMAN Fatty acid desaturase 6 (sprot)

A fatty acid desaturase 6 that is encoded in the genome of human.


DTX3_HUMAN Probable E3 ubiquitin-protein ligase DTX3 (sprot)

A protein deltex-3 that is encoded in the genome of human.


ZN565_HUMAN Zinc finger protein 565 (sprot)

A zinc finger protein 565 that is encoded in the genome of human.


ZIC4_HUMAN Zinc finger protein ZIC 4 (sprot)

A zinc finger protein ZIC 4 that is encoded in the genome of human.


ACOT4_HUMAN Peroxisomal succinyl-coenzyme A thioesterase (sprot)

A peroxisomal succinyl-coenzyme A thioesterase that is encoded in the genome of human.


saturated monocarboxylic acid metabolic process

The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.


unsaturated monocarboxylic acid metabolic process

The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.


dicarboxylic acid metabolic process

The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).


CS047_HUMAN Uncharacterized protein C19orf47 (sprot)

An uncharacterized protein C19orf47 that is encoded in the genome of human.


TM102_HUMAN Transmembrane protein 102 (sprot)

A transmembrane protein 102 that is encoded in the genome of human.


regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.


ASCC1_HUMAN Activating signal cointegrator 1 complex subunit 1 (sprot)

An activating signal cointegrator 1 complex subunit 1 that is encoded in the genome of human.


BANP_HUMAN Protein BANP (sprot)

A protein BANP that is encoded in the genome of human.


LRC57_HUMAN Leucine-rich repeat-containing protein 57 (sprot)

A leucine-rich repeat-containing protein 57 that is encoded in the genome of human.


EIF1A_HUMAN Probable RNA-binding protein EIF1AD (sprot)

A probable RNA-binding protein EIF1AD that is encoded in the genome of human.


SR1IP_HUMAN Protein SREK1IP1 (sprot)

A protein SFRS12IP1 that is encoded in the genome of human.


CDRT4_HUMAN CMT1A duplicated region transcript 4 protein (sprot)

A CMT1A duplicated region transcript 4 protein that is encoded in the genome of human.


SCAI_HUMAN Protein SCAI (sprot)

A protein SCAI that is encoded in the genome of human.


SNX31_HUMAN Sorting nexin-31 (sprot)

A sorting nexin-31 that is encoded in the genome of human.


KRI1_HUMAN Protein KRI1 homolog (sprot)

A protein KRI1 that is encoded in the genome of human.


TAC2N_HUMAN Tandem C2 domains nuclear protein (sprot)

A tandem C2 domains nuclear protein that is encoded in the genome of human.


TRIML_HUMAN Probable E3 ubiquitin-protein ligase TRIML1 (sprot)

A probable E3 ubiquitin-protein ligase TRIML1 that is encoded in the genome of human.


WSDU1_HUMAN WD repeat, SAM and U-box domain-containing protein 1 (sprot)

A WD repeat, SAM and U-box domain-containing protein 1 that is encoded in the genome of human.


ANR53_HUMAN Ankyrin repeat domain-containing protein 53 (sprot)

An ankyrin repeat domain-containing protein 53 that is encoded in the genome of human.


TOPZ1_HUMAN Protein TOPAZ1 (sprot)

A protein TOPAZ1 that is encoded in the genome of human.


DAAF3_HUMAN Dynein axonemal assembly factor 3 (sprot)

A dynein axonemal assembly factor 3 that is encoded in the genome of human.


BOLL_HUMAN Protein boule-like (sprot)

A protein boule-like that is encoded in the genome of human.


YO010_HUMAN Putative transmembrane protein FLJ36131 (sprot)


GAR2_HUMAN Golgi-associated RAB2 interactor protein 2 (sprot)

A Golgi-associated RAB2 interactor protein 2 that is encoded in the genome of human.


TMM75_HUMAN Putative protein encoded by LINC02912 (sprot)

A putative protein encoded by LINC02912 that is encoded in the genome of human.


F181A_HUMAN Protein FAM181A (sprot)

A protein FAM181A that is encoded in the genome of human.


ZN610_HUMAN Zinc finger protein 610 (sprot)

A zinc finger protein 610 that is encoded in the genome of human.


LMTD1_HUMAN Lamin tail domain-containing protein 1 (sprot)

A lamin tail domain-containing protein 1 that is encoded in the genome of human.


LMBL4_HUMAN Lethal(3)malignant brain tumor-like protein 4 (sprot)

A lethal(3)malignant brain tumor-like protein 4 that is encoded in the genome of human.


NLS1_HUMAN Sodium-dependent lysophosphatidylcholine symporter 1 (sprot)

A sodium-dependent lysophosphatidylcholine symporter 1 that is encoded in the genome of human.


regulation of phosphatidylcholine metabolic process

Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process.


regulation of phosphatidylethanolamine metabolic process

Any process that modulates the frequency, rate or extent of phosphatidylethanolamine metabolic process.


regulation of phosphatidylserine metabolic process

Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process.


Enables the directed movement of lysophospholipids from one side of a membrane to the other. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.


Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.


lysophospholipid translocation

The movement of a lysophospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.


TERB1_HUMAN Telomere repeats-binding bouquet formation protein 1 (sprot)

A telomere repeats-binding bouquet formation protein 1 that is encoded in the genome of human.


ZN383_HUMAN Zinc finger protein 383 (sprot)

A zinc finger protein 383 that is encoded in the genome of human.


CCD63_HUMAN Coiled-coil domain-containing protein 63 (sprot)

A coiled-coil domain-containing protein 63 that is encoded in the genome of human.


IQUB_HUMAN IQ and ubiquitin-like domain-containing protein (sprot)

An IQ and ubiquitin-like domain-containing protein that is encoded in the genome of human.


TTC29_HUMAN Tetratricopeptide repeat protein 29 (sprot)

A tetratricopeptide repeat protein 29 that is encoded in the genome of human.


CL050_HUMAN Uncharacterized protein C12orf50 (sprot)

An uncharacterized protein C12orf50 that is encoded in the genome of human.


PNDC1_HUMAN Poly(A)-specific ribonuclease PNLDC1 (sprot)

A poly(A)-specific ribonuclease PNLDC1 that is encoded in the genome of human.


CBY2_HUMAN Protein chibby homolog 2 (sprot)

A protein chibby homolog 2 that is encoded in the genome of human.


TEX45_HUMAN Testis-expressed protein 45 (sprot)

A protein that is a translation product of the TEX45 gene in human.


FA47B_HUMAN Protein FAM47B (sprot)

A protein FAM47B that is encoded in the genome of human.


POC5_HUMAN Centrosomal protein POC5 (sprot)

A centrosomal protein POC5 that is encoded in the genome of human.


TEX19_HUMAN Testis-expressed protein 19 (sprot)

A testis-expressed protein 19 that is encoded in the genome of human.


MARHA_HUMAN Probable E3 ubiquitin-protein ligase MARCHF10 (sprot)

A probable E3 ubiquitin-protein ligase MARCHF10 that is encoded in the genome of human.


THAP8_HUMAN THAP domain-containing protein 8 (sprot)

A THAP domain-containing protein 8 that is encoded in the genome of human.


A16L2_HUMAN Protein Atg16l2 (sprot)

A protein Atg16l2 that is encoded in the genome of human.


I17RC_HUMAN Interleukin-17 receptor C (sprot)

An interleukin-17 receptor C that is encoded in the genome of human.


interleukin-17 receptor activity

Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


ZN579_HUMAN Zinc finger protein 579 (sprot)

A zinc finger protein 579 that is encoded in the genome of human.


ANKL1_HUMAN Ankyrin repeat and LEM domain-containing protein 1 (sprot)

An ankyrin repeat and LEM domain-containing protein 1 that is encoded in the genome of human.


regulation of lymphoid progenitor cell differentiation

Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.


CI106_HUMAN Putative uncharacterized protein encoded by LINC02913 (sprot)


ZSCA4_HUMAN Zinc finger and SCAN domain-containing protein 4 (sprot)

A zinc finger and SCAN domain-containing protein 4 that is encoded in the genome of human.


MIGA1_HUMAN Mitoguardin 1 (sprot)

A mitoguardin 1 that is encoded in the genome of human.


ZBT38_HUMAN Zinc finger and BTB domain-containing protein 38 (sprot)

A zinc finger and BTB domain-containing protein 38 that is encoded in the genome of human.


ZBT8B_HUMAN Zinc finger and BTB domain-containing protein 8B (sprot)

A zinc finger and BTB domain-containing protein 8B that is encoded in the genome of human.


PMGT2_HUMAN Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (sprot)

A protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 that is encoded in the genome of human.


TDRD5_HUMAN Tudor domain-containing protein 5 (sprot)

A tudor domain-containing protein 5 that is encoded in the genome of human.


pi-body

A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.


FNDC5_HUMAN Fibronectin type III domain-containing protein 5 (sprot)

A fibronectin type III domain-containing protein 5 that is encoded in the genome of human.


PR38A_HUMAN Pre-mRNA-splicing factor 38A (sprot)

A pre-mRNA-splicing factor 38A that is encoded in the genome of human.


precatalytic spliceosome

A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.


KDF1_HUMAN Keratinocyte differentiation factor 1 (sprot)

A keratinocyte differentiation factor 1 that is encoded in the genome of human.


SMYD1_HUMAN Histone-lysine N-methyltransferase SMYD1 (sprot)

A histone-lysine N-methyltransferase SMYD1 that is encoded in the genome of human.


UBP38_HUMAN Ubiquitin carboxyl-terminal hydrolase 38 (sprot)

A ubiquitin carboxyl-terminal hydrolase 38 that is encoded in the genome of human.


ZN511_HUMAN Zinc finger protein 511 (sprot)

A zinc finger protein 511 that is encoded in the genome of human.


MLKL_HUMAN Mixed lineage kinase domain-like protein (sprot)

A mixed lineage kinase domain-like protein that is encoded in the genome of human.


execution phase of necroptosis

A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died.


F184A_HUMAN Protein FAM184A (sprot)

A protein FAM184A that is encoded in the genome of human.


GALD1_HUMAN Glutamine amidotransferase-like class 1 domain-containing protein 1 (sprot)

A glutamine amidotransferase-like class 1 domain-containing protein 1 that is encoded in the genome of human.


ZN527_HUMAN Zinc finger protein 527 (sprot)

A zinc finger protein 527 that is encoded in the genome of human.


ANR52_HUMAN Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (sprot)

A serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C that is encoded in the genome of human.


AT11C_HUMAN Phospholipid-transporting ATPase IG (sprot)

A phospholipid-transporting ATPase IG that is encoded in the genome of human.


ZFP62_HUMAN Zinc finger protein 62 homolog (sprot)

A zinc finger protein 62 that is encoded in the genome of human.


SYT14_HUMAN Synaptotagmin-14 (sprot)

A synaptotagmin-14 that is encoded in the genome of human.


UN13C_HUMAN Protein unc-13 homolog C (sprot)

A protein unc-13 homolog C that is encoded in the genome of human.


KDM1B_HUMAN Lysine-specific histone demethylase 2 (sprot)

A lysine-specific histone demethylase 2 that is encoded in the genome of human.


AFG2A_HUMAN ATPase family gene 2 protein homolog A (sprot)

A ribosome biogenesis protein SPATA5 that is encoded in the genome of human.


FANCB_HUMAN Fanconi anemia group B protein (sprot)

A Fanconi anemia group B protein that is encoded in the genome of human.


DTWD2_HUMAN tRNA-uridine aminocarboxypropyltransferase 2 (sprot)

A tRNA-uridine aminocarboxypropyltransferase 2 that is encoded in the genome of human.


ZSCA1_HUMAN Zinc finger and SCAN domain-containing protein 1 (sprot)

A zinc finger and SCAN domain-containing protein 1 that is encoded in the genome of human.


CT203_HUMAN Uncharacterized protein C20orf203 (sprot)

A protein that is a translation product of the C20orf203 gene in human.


T229B_HUMAN Transmembrane protein 229B (sprot)

A transmembrane protein 229B that is encoded in the genome of human.


KLH23_HUMAN Kelch-like protein 23 (sprot)

A kelch-like protein 23 that is encoded in the genome of human.


GLIS1_HUMAN Zinc finger protein GLIS1 (sprot)

A zinc finger protein GLIS1 that is encoded in the genome of human.


NHLC2_HUMAN NHL repeat-containing protein 2 (sprot)

An NHL repeat-containing protein 2 that is encoded in the genome of human.


AVL9_HUMAN Late secretory pathway protein AVL9 homolog (sprot)

A late secretory pathway protein AVL9 that is encoded in the genome of human.


KY_HUMAN Kyphoscoliosis peptidase (sprot)

A kyphoscoliosis peptidase that is encoded in the genome of human.


CYAC3_HUMAN Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3 (sprot)

A lysosomal membrane ascorbate-dependent ferrireductase CYB561A3 that is encoded in the genome of human.


DRAXI_HUMAN Draxin (sprot)

A draxin that is encoded in the genome of human.


commissural neuron differentiation in spinal cord

The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.


S43A3_HUMAN Equilibrative nucleobase transporter 1 (sprot)

An equilibrative nucleobase transporter 1 that is encoded in the genome of human.


XXLT1_HUMAN Xyloside xylosyltransferase 1 (sprot)

A xyloside xylosyltransferase 1 that is encoded in the genome of human.


Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine. The enzyme, found in animals and insects, is involved in the biosynthesis of the alpha-D-xylosyl-(1->3)-alpha-D-xylosyl-(1->3)- beta-D-glucosyl trisaccharide on epidermal growth factor-like (EGF- like) domains.


GOLM1_HUMAN Golgi membrane protein 1 (sprot)

A Golgi membrane protein 1 that is encoded in the genome of human.


GT251_HUMAN Procollagen galactosyltransferase 1 (sprot)

A procollagen galactosyltransferase 1 that is encoded in the genome of human.


SUMF2_HUMAN Inactive C-alpha-formylglycine-generating enzyme 2 (sprot)

An inactive C-alpha-formylglycine-generating enzyme 2 that is encoded in the genome of human.


SIDT2_HUMAN SID1 transmembrane family member 2 (sprot)

A SID1 transmembrane family member 2 that is encoded in the genome of human.


nucleic acid transmembrane transporter activity

Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.


SUMF1_HUMAN Formylglycine-generating enzyme (sprot)

A formylglycine-generating enzyme that is encoded in the genome of human.


Catalysis of the reaction: A [sulfatase]-L-cysteine + O2 + 2 a thiol = a [sulfatase]-3-oxo-L-alanine + hydrogen sulfide + a disulfide + H2O.


PGLT1_HUMAN Protein O-glucosyltransferase 1 (sprot)

A protein O-glucosyltransferase 1 that is encoded in the genome of human.


muscle tissue development

The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.


T178A_HUMAN Transmembrane protein 178A (sprot)

A transmembrane protein 178A that is encoded in the genome of human.


UBAC2_HUMAN Ubiquitin-associated domain-containing protein 2 (sprot)

A ubiquitin-associated domain-containing protein 2 that is encoded in the genome of human.


PCYXL_HUMAN Prenylcysteine oxidase-like (sprot)

A prenylcysteine oxidase-like that is encoded in the genome of human.


prenylcysteine catabolic process

The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.


TM87A_HUMAN Transmembrane protein 87A (sprot)

A transmembrane protein 87A that is encoded in the genome of human.


RDH13_HUMAN Retinol dehydrogenase 13 (sprot)

A retinol dehydrogenase 13 that is encoded in the genome of human.


response to high light intensity

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.


MFSD9_HUMAN Major facilitator superfamily domain-containing protein 9 (sprot)

A major facilitator superfamily domain-containing protein 9 that is encoded in the genome of human.


PCSK9_HUMAN Proprotein convertase subtilisin/kexin type 9 (sprot)

A proprotein convertase subtilisin/kexin type 9 that is encoded in the genome of human.