DNA ligase (NAD+) activity

Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).


cellular process involved in reproduction in multicellular organism

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.


diphosphotransferase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).


phenylacetyl-CoA dehydrogenase activity

Catalysis of the reaction: 2 1,4-benzoquinone + H2O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.


8-oxocoformycin reductase activity

Catalysis of the reaction: coformycin + NADP+ = 8-oxocoformycin + 2 H+ + NADPH.


Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.


retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission

Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.


intronic box H/ACA snoRNA processing

Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.


negative regulation of establishment or maintenance of cell polarity regulating cell shape

Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.


Catalysis of the reaction: tetrahydroxypteridine = H+ + xanthine-8-carboxylate.


cellular response to decane

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.


maintenance of seed dormancy

Any process that maintains a seed in a dormant state.


Catalysis of the reaction: (S)-reticulinium(1+) + S-adenosyl-L-methionine <=> H+ + laudanine(1+) + S-adenosyl-L-homocysteine.


fluorene oxygenase activity

Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.


chlorophyll synthetase activity

Catalysis of the reaction: chlorophyllide a + 2 H+ + phytyl diphosphate = chlorophyll a + diphosphate.


L-idonate transmembrane transporter activity

Enables the transfer of L-idonate from one side of a membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.


endothelial microparticle formation

The cellular component organization process in which microparticles bud off from an endothelial cell.


cellular response to alcohol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.


envenomation resulting in plasminogen activation in another organism

The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.


purine ribonucleotide transmembrane transporter activity

Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.


crotonyl-CoA reductase activity

Catalysis of the reduction of crotonyl-CoA to butyryl-CoA.


negative regulation of lateral mesodermal cell fate determination

Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.


peptidyl-tryptophan hydroxylation

The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.


Catalysis of the reaction: ATP + L-glutamate + L-propargylglycine = ADP + H+ + L-gamma-glutamyl-L-propargylglycine + phosphate.


dimethylarsinate reductase activity

Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O.


voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels

Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission.


cellular response to erythromycin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.


positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.


Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+.


diplotene

The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.


nitrogen fixation

The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.


Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H2O = LL-2,6-diaminopimelate + acetate.


delta-carotene catabolic process

The chemical reactions and pathways resulting in the breakdown of delta-carotene.


viral gene expression

A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.


Catalysis of the reaction: UDP-alpha-D-glucose + 4-hydroxylamino-2,6-dinitrotoluene <=> 4-hydroxylamino-2,6-dinitrotoluene-O-glucoside + UDP + H+.


plant organ formation

The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.


organic cyclic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of organic cyclic compound.


regulation of mini excitatory postsynaptic potential

Any process that modulates the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.


negative regulation of raffinose biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.


glucan metabolic process

The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.


peptidyl-threonine modification

The modification of peptidyl-threonine.


maintenance of location

Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.


seed dormancy process

A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.


Wnt signaling pathway involved in kidney development

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.


anterior cibarial plate morphogenesis

The process in which the anatomical structures of the anterior cibarial plate are generated and organized.


inulin catabolic process

The chemical reactions and pathways resulting in the breakdown of inulin.


afferent axon development in anterior lateral line nerve

The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.


protease localization to mast cell secretory granule

Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.


fructose catabolic process

The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.


flavonoid sulfotransferase activity

Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.


positive regulation of cellobiose catabolic process

Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.


peptidyl-lysine carboxyethylation

The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.


arugosin metabolic process

The chemical reactions and pathways involving arugosin.


negative regulation of response to amylopectin

Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin.


Catalysis of the reaction: 1-18:3-2-18:1-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.


leucine metabolic process

The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.


Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine.


Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.


Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.


thymine dehydrogenase activity

Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2.


abequosyltransferase activity

Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.


anaerobic phenol-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.


epithelial cell migration involved in metanephric nephron tubule morphogenesis

The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.


disproportionation of elemental sulfur

The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.


negative regulation of lung alveolus development

Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.


macrolide metabolic process

The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.


Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.


PRC1 complex binding

Binding to a PRC1 complex.


purine nucleobase salvage

Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.


regulation of adenosine transport

Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


aerobic respiration, using nitrite as electron donor

The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.


Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.


COPII vesicle uncoating

The process in which COPII vesicle coat proteins are disassembled, and released.


renal cortex development

The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.


apical dendrite morphogenesis

The process in which the anatomical structures of an apical dendrite are generated and organized.


1-phenylethanol dehydrogenase activity

Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2.


sulfite transmembrane transporter activity

Enables the transfer of sulfite ions from one side of a membrane to the other.


discadenine biosynthetic process

The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.


response to brassinosteroid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.


bacteriochlorophyll binding

Binding to bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.


pouch outgrowth involved in semicircular canal formation

The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.


ensheathment of neuronal cell bodies

The process in which satellite glial cells isolate neuronal cell bodies.


indole-2-monooxygenase activity

Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O.


L-lysine 6-oxidase activity

Catalysis of the reaction: L-lysine + H2O + O2 = allysine + H2O2 + NH4.


GDP-mannose biosynthetic process from mannose

The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.


leucoanthocyanidin reductase activity

Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.


double-strand break repair via single-strand annealing, removal of nonhomologous ends

During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.


killing by virus of host cell by post-segregational killing

The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.


The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactosaminogalactan. GAG is a heteropolysaccharide composed of alpha-1,4 linked galactose, N-acetyl galactosamine (GalNAc) and galactosamine (GalN).


regulation of L-glutamine import across plasma membrane

Any process that modulates the frequency, rate or extent of L-glutamine import into cell.


choline-sulfatase activity

Catalysis of the reaction: choline sulfate + H2O = choline + H+ + sulfate.


UDP-rhamnose metabolic process

The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.


6-phosphoglucan, water dikinase activity

Catalysis of the reaction: n ATP + n H2O + a 6-phosphogluco-maltodextrin = n AMP + n hydrogenphosphate + a poly-6-phosphogluco-maltodextrin.


TRAIL death-inducing signaling complex assembly

The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.


sn-glycerol 3-phosphate binding

Binding to sn-glycerol 3-phosphate.


evasion of host innate immune recognition

A process by which a symbiont avoids recognition by host's innate immune response by altering a conserved molecule recognized by the host's cell surface and intracellular innate immune receptors, including Toll-like receptors, and NOD-like receptors. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of ascus development

Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.


positive regulation of border follicle cell migration

Any process that activates or increases the frequency, rate or extent of border follicle cell migration.


negative regulation of horizontal cell localization

Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.


lupeol 28-monooxygenase activity

Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O.


shikimate 3-dehydrogenase (NADP+) activity

Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.


10-oxogeraniol oxidoreductase activity

Catalysis of the reaction: (6E)-8-oxogeraniol + NADP <=> (6E)-8-oxogeranial + NADPH + H+.


viral budding from nuclear membrane

A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.


structural constituent of egg chorion

The action of a molecule that contributes to the structural integrity of an egg chorion. An example of this is found in Drosophila melanogaster.


Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O.


negative regulation of hormone metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.


lymph gland plasmatocyte differentiation

The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.


violaxanthin de-epoxidase activity

Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.


pigment accumulation

The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.


negative regulation of cell differentiation involved in phenotypic switching

Any process that stops, prevents or reduces the frequency, rate or extent of cell differentiation involved in phenotypic switching.


L-ascorbate oxidase activity

Catalysis of the reaction: 4 L-ascorbate + O2 <=> 4 monodehydroascorbate + 2 H2O.


RNA strand-exchange activity

Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.


choline biosynthetic process via CDP-choline

The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.


superior raphe nucleus development

The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.


creatinine catabolic process to formate

The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.


4-hydroxybenzoate amino acid synthetase activity

Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate.


negative regulation of synoviocyte proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.


dirigent protein activity

Catalysis of the reaction: 2 H+ + 2 coniferol + O2 <=> (+)-pinoresinol + 2 H2O.


retinoic acid receptor signaling pathway involved in lung bud formation

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.


response to diacyl bacterial lipopeptide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.


flavin-containing compound metabolic process

The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.


high-affinity zinc transmembrane transporter activity

Enables the transfer of zinc ions (Zn2+) from one side of a membrane to the other, probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


shikimate transmembrane transporter activity

Enables the transfer of shikimate from one side of a membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.


mesonephric glomerular parietal epithelial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.


peptide cross-linking via (2R,6R)-lanthionine

The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine).


fruit ripening

An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.


response to photoperiod, blue light

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.


halogen metabolic process

The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.


corrin metabolic process

The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


peptidyl-threonine octanoylation

The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.


positive regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process

Any process that activates or increases the frequency, rate or extent of an adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in some heart process.


renal capsule specification

The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


hyponitrite reductase activity

Catalysis of the reaction: 2 hydroxylamine + 2 NAD+ = 2 H+ + hyponitrous acid + 2 NADH.


Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.


neural crest-derived cardiac glial cell differentiation

The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.


nucleobase metabolic process

The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.


mitochondrial protein-transporting ATPase activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.


molybdenum incorporation into metallo-sulfur cluster

The incorporation of molybdenum into a metallo-sulfur cluster.


cellular response to glutathione

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.


formation of peptidyl-cystine persulfide by sulphur transfer from H2S

The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.


1-deoxy-D-xylulose 5-phosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.


regulation of stomatal complex patterning

Any process that modulates the frequency, rate or extent of stomatal complex patterning.


response to mycophenolic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.


3,5-dichloro-THPH methyl transferase activity

Catalysis of the reaction: (3,5-dichloro-2,4,6-trihydroxyphenyl)hexan-1-one + S-adenosyl-L-methionine = 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one + H+ + S-adenosyl-L-homocysteine.


UDP-glucuronic acid dehydrogenase activity

Catalysis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+.


Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.


oxalate catabolic process

The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.


4-hydroxytryptamine kinase activity

Catalysis of the reaction: 4-hydroxytryptamine + ATP = 4-hydoxytryptamine 4-phosphate + ADP + H+.


mammillotegmental axonal tract development

The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.


histone H2A K63-linked ubiquitination

A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.


NAD-dependent protein de-2-hydroxyisobutyrylase activity

Catalysis of the reaction: H2O + N6-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + NAD+ = 2''-O-(2-hydroxyisobutanoyl)-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


galactoxylomannan biosynthetic process

The chemical reactions and pathways resulting in the formation of the exopolysaccharide galactoxylomannan. Galactoxylomannan is produced by a pathogenic fungus and causes paralysis in some animals.


negative regulation of cellotriose metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.


phototropism

The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.


formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine

The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.


mesonephric nephron tubule morphogenesis

The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.


peptidyl-pyrromethane cofactor linkage

The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.


negative regulation of vasculature development

Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.


corticospinal neuron axon guidance through the cerebral peduncle

The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.


The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.


(R)-4-hydroxyphenyllactate dehydrogenase (NADPH) activity

Catalysis of the reaction: NADP+ + (R)-3-(4-hydroxyphenyl)lactate = NADPH + H+ + 3-(4-hydroxyphenyl)pyruvate.


regulation of cellodextrin catabolic process

Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.


sevenless signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


negative regulation of nerve growth factor production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).


eoxin E4 synthase activity

Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.


medulla reticulospinal tract morphogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.


cellular response to lipoprotein particle stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.


FAT10 conjugating enzyme activity

Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y = Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.


Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.


snRNA methylation

The posttranscriptional addition of methyl groups to specific residues in an snRNA molecule.


regulation of vesicle docking

Any process that modulates the frequency, rate or extent of vesicle docking.


antennal development

The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.


angioblast cell differentiation

The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).


peptidyl-lysine malonylation

The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.


adult salivary gland boundary specification

Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.


The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.


perturbation by symbiont of host actin cytoskeleton via actin filament reorganization

The process in which an organism effects a change that impairs the structure or function of the host actin cytoskeleton by reorganizing the actin filaments, in a way that keeps the total filementous actin remains approximately constant. The host is defined as the larger of the organisms involved in a symbiotic interaction.


cell-matrix recognition

Cell recognition that involves the interaction of the cell with the extracellular matrix.


mammary gland duct regression in males

The process in which the epithelium of the mammary duct is destroyed in males.


N-methyl nucleosidase activity

Catalysis of the reaction: 7-methylxanthosine + H2O = 7-methylxanthine + H+ + ribofuranose.


phosphoserine-tRNA(Cys) ligase activity

Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).


protein localization to cytosolic proteasome complex

A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.


nucleobase binding

Binding to a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.


protein localization to actin cortical patch

A process in which a protein is transported to, or maintained in, an actin cortical patch.


phlobaphene metabolic process

The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.


positive regulation of heart rate by norepinephrine

The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.


basket cell precursor proliferation

The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


gluconate dehydratase activity

Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O.


bisdemethoxycurcumin synthase activity

Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide.


Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.


Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.


1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity (SN2-16:2 forming)

Catalysis of the reaction: 1-18:2-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor = 1-18:2-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


glial cell migration in anterior lateral line nerve

The movement of a glial cell along the axons in the anterior lateral line nerve.


regulation of proline import across plasma membrane

Any process that modulates the frequency, rate or extent of proline import into cell.


bromide peroxidase activity

Catalysis of the reaction: 2 R-H + 2 bromide + H2O2 = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.


regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.


schizogony

Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.


inhibitory C-type lectin receptor signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.


vacuole-mitochondria membrane tethering

The attachment of a mitochondrial membrane to a vacuolar membrane via molecular tethers that physically bridge their respective membranes and attach them to each other. The tethering may facilitate exchange of metabolites between the organelles.


Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.


Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.


disruption of host cell envelope during viral entry

The disruption of host cell envelope by viral proteins during virus entry.


plasmid maintenance

The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.


cell growth mode switching, filamentous to budding

The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.


regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.


cellular response to diosgenin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.


propan-2-ol metabolic process

The chemical reactions and pathways involving propan-2-ol.


dehiscence

The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.


isoflavonoid metabolic process

The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.


sesamin synthase activity

Catalysis of the reaction: H+ + (+)-piperitol + NADPH + O2 <=> (+)-sesamin + NADP + 2 H2O.


CCL19-activated CCR7 signaling pathway

The series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


anhydrosialidase activity

Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.


Mo-molybdopterin cofactor catabolic process

The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.


phosphogluconate dehydratase activity

Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O.


Catalysis of the reaction: UDP-alpha-D-glucose(2-) + medicagenate <=> UDP(3-) + a medicagenate monoglucoside.


quinoline 2-oxidoreductase activity

Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.


negative regulation of lamellocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


Catalysis of the reaction: UDP-N-acetyl-alpha-D-quinovosamine + NAD(P) = UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose + H+ + NAD(P)H.


negative regulation of cell differentiation involved in stem cell population maintenance

Any negative regulation of cell differentiation that is involved in stem cell population maintenance.


Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.


slime layer organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.


protein-heme P460 linkage

The linkage of protein to heme P460.


regulation of neurotransmitter loading into synaptic vesicle

Any process that modulates the frequency, rate or extent of neurotransmitter loading into synaptic vesicles.


D-arabitol catabolic process to xylulose 5-phosphate

The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.


RNA polymerase IV activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


verruculogen biosynthetic process

The chemical reactions and pathways resulting in the formation of verruculogen.


anaerobic fructose catabolic process

The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.


molybdenum cofactor cytidylyltransferase activity

Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.


histidine N-acetyltransferase activity

Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H+.


positive regulation of nematode larval development

Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


eye-antennal disc morphogenesis

The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.


negative regulation of L-dopa decarboxylase activity

Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.


regulation of foraging behavior

Any process that modulates the frequency, rate or extent of foraging behavior.


gentisate decarboxylase activity

Catalysis of the reaction: 2,5-dihydroxybenzoate + H+ = CO2 + hydroquinone.


peptide cross-linking via L-cystine

The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.


positive regulation of systemic acquired resistance

Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.


gibberellin biosynthetic process

The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.


phytochrome chromophore biosynthetic process

The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.


myrtenol dehydrogenase activity

Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.


establishment of plant organ orientation

The process that determines the orientation of a plant organ or tissue with reference to an axis.


cardiac neuron fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.


response to desipramine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.


mannan biosynthetic process

The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.


fatty acid beta-oxidation, unsaturated, even number

A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).


inorganic molecular entity transmembrane transporter activity

Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon.


eukaryotic translation initiation factor 4F complex assembly

The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.


tRNA N-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA.


terpenoid catabolic process

The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.


positive regulation of oogonium development

Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.


alcohol O-hexanoyltransferase activity

Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.


cis-zeatin UDP glycosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin = H+ + 9-(alpha-D-glucosyl)-cis-zeatin + UDP.


inosine kinase activity

Catalysis of the reaction: ATP + inosine = ADP + IMP.


The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.


negative regulation of metabolic activity involved in hibernation

The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.


cellular biogenic amine catabolic process

The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.


semaphorin-plexin signaling pathway involved in neuron projection guidance

Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.


Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD+ = 7,8-dihydroxykynurenate + H+ + NADH.


zeaxanthin bis(beta-D-glucoside) metabolic process

The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).


Catalysis of the reaction: UDP-alpha-D-glucose + gypsogenin = gypsogenin-28-beta-D-glucoside + UDP.


(+)-delta-cadinene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.


regulation of anterograde synaptic vesicle transport

Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.


protein C-linked glycosylation

A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.


hermaphrodite somatic sex determination

The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.


ornithine N-benzoyltransferase activity

Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H+.


positive regulation of acetylcholine metabolic process

Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


regulation of xylan catabolic process

Any process that modulates the frequency, rate or extent of xylan catabolic process.


positive regulation of catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.


mesonephric distal tubule morphogenesis

The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.


morphine 6-dehydrogenase activity

Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.


iron-sulfur-molybdenum cofactor metabolic process

The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.


cellular response to cesium ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.


bromoxynil nitrilase activity

Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH4. Involved in the bacterial degradation of the herbicide bromoxynil.


undecan-2-one biosynthetic process

The chemical reactions and pathways resulting in the formation of undecan-2-one.


UDP-D-xylose metabolic process

The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.


protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine

The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.


negative regulation of response to wounding

Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.


The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.


The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.


UMP/dUMP kinase activity

Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.


negative regulation of pulmonary blood vessel remodeling

Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.


Notch signaling pathway involved in camera-type eye photoreceptor fate commitment

The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.


3-oxo-dodecanoyl-ACP hydrolase activity

Catalysis of the reaction: H2O + a 3-oxo-dodecanoyl-[acp] = 3-oxododecanoate + H+ + a holo-[acyl-carrier protein].


adenylyltransferase activity

Catalysis of the transfer of an adenylyl group to an acceptor.


ABC-type oligogalacturonide transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).


Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.


negative regulation of small intestine smooth muscle contraction

Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.


specification of ovule identity

The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


4-phenanthrol sulfotransferase activity

Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.


high-affinity IgA receptor activity

Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.


anterograde trans-synaptic signaling by trans-synaptic protein complex

Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.


neuroblast fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.


RNA-binding transcription regulator activity

A transcription regulator activity that modulates the transcription of specific gene sets via selective and non-covalent binding to a specific RNA sequence. This function is known to occur in phages and viruses, for example the lambda N and the HIV tat proteins are necessary to allow RNA polymerase to read through terminator sequences.


specification of metanephric distal tubule identity

The process in which the distal tubule of the metanephric nephron acquires its identity.


selenomethionine gamma-lyase activity

Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.


Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.


taxoid 7beta-hydroxylase activity

Catalysis of the reaction: taxusin + [reduced NADPH-hemoprotein reductase] + O2 = 7beta-hydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O and 2alpha-hydroxytaxusin + [reduced NADPH-hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + [oxidized NADPH-hemoprotein reductase] + H2O.


carbohydrate-importing ABC transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).


R1/R6 development

The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.


hexose oxidase activity

Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.


dihydropyrimidine dehydrogenase (NAD+) activity

Catalysis of the reaction: a 5,6-dihydropyrimidine (5,6-dihydrouracil or 5,6-dihydrothymine) + NAD+ = a pyrimidine (uracil or thymine) + NADH + H+.


negative regulation of cerebellar neuron development

Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.


organic cyclic compound metabolic process

The chemical reactions and pathways involving organic cyclic compound.


imaginal disc development

The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).


determination of lung left/right asymmetry

Determination of the asymmetric location of the lungs with respect to the left and right halves of the organism.


oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.


delphinidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity

Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> delphinidin 3,7-di O-beta-D-glucoside + ferulate + H+.


response to bisphenol A

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.


regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis

Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.


positive regulation of mammary placode formation by mesenchymal-epithelial signaling

Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.


neuropeptide F receptor activity

Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.


rhamnogalacturonan II metabolic process

The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.


pyoverdine biosynthetic process

The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.


regulation of somatic muscle development

Any process that regulates the rate, frequency or extent of somatic muscle development.


2-oxo-acid reductase activity

Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.


negative regulation of alcohol biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.


tolerance induction in gut-associated lymphoid tissue

Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).


raucaffricine beta-glucosidase activity

Catalysis of the reaction: H2O + raucaffricine = D-glucose + vomilenine.


Catalysis of the reaction: isovitexin + UDP-D-glucose = H+ + isovitexin 2''-O-beta-D-glucoside + UDP.


negative regulation of cartilage condensation

Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.


regulation of renal water transport

Any process that modulates the frequency, rate or extent of renal water transport.


fructan biosynthetic process

The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.


beta-hydroxybutyrate transmembrane transporter activity

Enables the transfer of beta-hydroxybutyrate from one side of a membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.


vacuolar localization

Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell.


nucleobase catabolic process

The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.


streptomycin metabolic process

The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.


pyridine biosynthetic process

The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.


spindle pole body anchor activity

The binding activity of a protein that brings together the spindle pole body and one or more other molecules, permitting them to function in a coordinated way.


Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.


glucuronoside metabolic process

The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.


regulation of lateral root development

Any process that modulates the frequency, rate or extent of lateral root development.


Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H+ = 2,5-dioxopentanoate + CO2 + H2O.


instar larval or pupal morphogenesis

The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.


response to rest involved in regulation of muscle adaptation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.


P-type magnesium transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) = ADP + phosphate + Mg2+(in).


Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.


stipitatonate decarboxylase activity

Catalysis of the reaction: H2O + stipitatonate = CO2 + H+ + stipitatate.


3-isopropylmalate dehydratase activity

Catalysis of the reaction: (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate.


negative regulation of humoral immune response

Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.


bicyclic nitroimidazole metabolic process

The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.


Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.


Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H+. This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.


negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.


cysteine biosynthetic process via S-sulfo-L-cysteine

The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.


The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.


methylenetetrahydrofolate reductase (ferredoxin) activity

Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.


cellular response to resveratrol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.


negative regulation of prostaglandin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin catabolic process.


interleukin-16 production

The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


selenomethionine-tRNA ligase activity

Catalysis of the reaction: ATP + L-selenomethionine + tRNA(Met) => AMP + diphosphate + selenomethionyl-tRNA(Met).


sperm plasma membrane disassembly

The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.


regulation of somitomeric trunk muscle development

Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.


GUU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GUU codon.


reception of an inductive signal

The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.


regulation of signal transduction involved in conjugation with cellular fusion

Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion.


B-1 B cell proliferation

The expansion of a B-1 B cell by cell division. Follows B cell activation.


interleukin-37 production

The appearance of interleukin-37 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.


mitochondrion-plasma membrane adaptor activity

The binding activity of a molecule that brings together a mitochondrion and a plasma membrane either via membrane lipid binding or by interacting with a mitochondrial outer membrane protein, to establish or maintain the localization of the mitochondrion.


organic heteropentacyclic compound catabolic process

The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.


IDP catabolic process

The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.


dUTP metabolic process

The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.


Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.


auxin-activated signaling pathway

The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.


cytidine salvage

Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.


ornithine N5-monooxygenase activity

Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.


hexose metabolic process

The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.


betaine reductase activity

Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.


positive regulation of flavonoid biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.


regulation of Wnt-mediated midbrain dopaminergic neuron differentiation

Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.


regulation of horizontal cell localization

Any process that modulates the frequency, rate or extent of horizontal cell localization.


positive regulation of ribosomal large subunit export from nucleus

Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.


Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.


lithocholate 6beta-hydroxylase activity

Catalysis of the reaction: H+ + lithocholate + NADPH + O2 = 6-beta-hydroxylithocholate + H2O + NADP+.


perithecium formation

The process of producing flask-shaped fruiting bodies, called perithecia. In the ascomycetous fungi such as Neurospora crassa and Sordaria macrospora, these perithecia are formed in the sexual phase and they discharge ascospores through the ostiolum at the tip of the perithecial neck.


secondary active cyanate transmembrane transporter activity

Enables the transfer of cyanate from one side of a membrane to the other.


N-acetylcitrulline deacetylase activity

Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.


negative regulation of hemocyte proliferation

Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.


Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.


negative regulation of cell wall organization or biogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.


thiocyanate catabolic process

The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.


sesquisabinene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + sesquisabinene.


aldehyde-lyase activity

Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.


post-embryonic anal fin morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.


positive regulation of the force of heart contraction by circulating norepinephrine

The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction.


regulation of inhibin secretion

Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.


proteinase-activated receptor activity

A G protein-coupled receptor activity that is activated by cleavage by a serine protease, exposing a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.


negative regulation of lactose biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.


low-affinity nitrate transmembrane transporter activity

Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


glycosyl compound biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosyl compound.


regulation of interphase mitotic telomere clustering

Any process that modulates the frequency, rate or extent of mitotic telomere clustering during interphase.


larval turning behavior

Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.


positive regulation of L-tyrosine import across plasma membrane

Any process that activates or increases the frequency, rate or extent of L-tyrosine import into the cell.


guanosine pentaphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.


migration in host

The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


glucarate dehydratase activity

Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O.


cyanamide metabolic process

The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.


recruitment of helicase-primase complex to DNA lesions

The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair.


syringal lignin biosynthetic process

The chemical reactions and pathways resulting in the formation of syringal lignin.


negative regulation of gonad development

Any process that stops, prevents or reduces the frequency, rate or extent of gonad development.


regulation of leukocyte mediated immunity

Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.


symbiont-mediated suppression of host autophagy

Any process in which a symbiont organism decreases the frequency, rate or extent of autophagy in the host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Pup transferase activity

Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.


acetylenecarboxylate hydratase activity, producing 3-oxopropanoate

Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.


Golgi vesicle uncoating

The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.


epithelium-like organization

The organization of a polarized cell layer during morphogenesis in protozoa; an example is found during culmination in D. discoideum, involving alpha and beta catenins.


fruit abscission

The controlled shedding of a fruit.


sphingolipid delta-8 desaturase activity

Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).


pyloric canal smooth muscle contraction

A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal part of the pylorus between the pyloric antrum and the pyloric sphincter.


GTP cyclohydrolase activity

Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.


perception of rate of movement

The series of events by which an organism senses the speed and direction of movement of the body and its parts.


intermediate filament depolymerization

Disassembly of intermediate filaments by the removal of component monomers from a filament.


masculinization of hermaphrodite soma

Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans.


glomerular epithelial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.


ammonium ion binding

Binding to ammonium ions (NH4+).


(Z)-gamma-bisabolene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.


D-pinitol dehydrogenase activity

Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADPH.


starch alpha-glucosidase activity

Catalysis of the reaction: starch + H2O = alpha-D-glucose.


alcohol dehydrogenase (cytochrome c) activity

Catalysis of the reaction: 2 [Fe(III)cytochrome c] + a primary alcohol = 2 [Fe(II)cytochrome c] + an aldehyde + 2 H+.


Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.


negative regulation of acylglycerol transport

Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport.


mesonephric tubule morphogenesis

The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.


centripetally migrating follicle cell migration

The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.


synthetic cannabinoid binding

Binding to synthetic cannabinoid.


transport-coupled glycolytic process through glucose-6-phosphate

The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.


lymphatic vascular process in circulatory system

A circulatory process that occurs at the level of the lymphatic vasculature.


regulation of pronephric nephron tubule development

Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.


xanthophore differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.


positive regulation of response to drug

Any process that activates or increases the frequency, rate or extent of response to drug.


tyramine receptor activity

Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.


negative regulation of deacetylase activity

Any process that stops, prevents or reduces the frequency, rate or extent of deacetylase activity.


trinitrotoluene metabolic process

The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.


glutathionylspermidine amidase activity

Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.


stomach fundus smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.


interleukin-28A production

The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


type IV pilus assembly

The assembly from its constituent parts of a type IV pilus.


The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.


alkane catabolic process

The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.


R7 cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor.


ensheathment of neurons

The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.


response to oxidopamine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxidopamine stimulus.


connective tissue growth factor production

The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


proton-dependent peptide secondary active transmembrane transporter activity

Enables the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.


endosulfan diol dehydrogenase activity

Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-.


Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine.


flower calyx development

The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.


Wnt-Frizzled-LRP5/6 complex assembly

The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex.


inferior salivary nucleus development

The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.


negative regulation of response to type II interferon

Any process that decreases the rate, frequency or extent of a response to type II interferon (interferon-gamma). Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.


metanephric cap formation

The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.


positive regulation of granuloma formation

Any process that activates or increases the frequency, rate, or extent of granuloma formation.


granzyme B localization to T cell secretory granule

Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.


prevention of polyspermy during double fertilization

The regulation of double fertilization forming a zygote and endosperm process that ensures that only a single sperm cell fertilizes one egg cell and another single sperm cell fertilizes one central cell.


atrial cardiac muscle cell membrane repolarization

The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.


3-cyano-L-alanine biosynthetic process

The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.


kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP.


2-carene synthase activity

Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid.


Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.


Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.


positive regulation of estrone secretion

Any process that activates or increases the frequency, rate or extent of estrone secretion.


regulation of kainate selective glutamate receptor signaling pathway

Any process that modulates the frequency, rate or extent of tge kainate selective glutamate receptor signaling pathway.


stress response to zinc ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.


peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid

The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.


response to transition metal nanoparticle

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.


culmination involved in sorocarp development

The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.


ATPase-coupled carboxylic acid transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).


glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group

Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.


negative regulation of L-lysine import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.


Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.


regulation of cardiac ventricle formation

Any process that modulates the frequency, rate or extent of cardiac ventricle formation.


regulation of DNA primase activity

Any process that modulates the frequency, rate or extent of DNA primase activity.


cytoneme morphogenesis

The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.


tatiopterin biosynthetic process

The chemical reactions and pathways resulting in the formation of tatiopterin.


negative regulation of cellular response to alcohol

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alcohol.


Catalysis of the reaction: octanoyl-CoA + a malonyl-[acyl-carrier protein] = a 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2.


thymidylate synthase (FAD) activity

Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.


cellular response to sodium phosphate

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.


nucleoside monophosphate metabolic process

The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.


cell wall integrity MAPK cascade

A MAPK cascade that contributes to cell wall organization or biogenesis.


positive regulation of the force of heart contraction by neuronal epinephrine

The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.


embryonic heart tube formation via epithelial folding

The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.


adhesin autotransporter activity

Enables the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively.


positive regulation of apoptotic process in bone marrow cell

Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process in the bone marrow.


coenzyme M metabolic process

The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


2-dehydro-3-deoxygluconokinase activity

Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H+.


regulation of pigmentation

Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism.


isoquinoline alkaloid biosynthetic process

The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


regulation of apoptotic process involved in metanephric nephron tubule development

Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.


regulation of short-day photoperiodism, flowering

Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.


Hulle cell development

The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


positive regulation of muscle cell apoptotic process

Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


ta-siRNA processing

A process leading to the generation of a functional trans-acting small interfering RNA (ta-siRNA). ta-siRNAs function like miRNAs to guide cleavage of target mRNAs.


cardiolipin synthase activity

Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.


symbiont-mediated suppression of host cGAS-STING signal transduction

A process in which a virus interferes with, inhibits or disrupt a cGAS/STING signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


positive regulation of stomatal complex development

Any process that activates or increases the frequency, rate or extent of stomatal complex development.


endothelial stalk cell fate specification

The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout.


radial glial cell fate commitment in forebrain

The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.


hydroperoxide reductase activity

Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.


retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.


The 2-hydroxyisobutyrylation of a lysine residue in a protein.


fibroblast growth factor receptor signaling pathway involved in lung induction

The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.


double fertilization forming a zygote and endosperm

Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.


protein localization to mitotic spindle midzone

A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.


ABC-type ferric-enterobactin transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).


nitrite efflux transmembrane transporter activity

Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.


UDP-D-apiose biosynthetic process

The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.


thylakoid membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.


cellular response to phenylpropanoid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.


cephalosporin C catabolic process

The chemical reactions and pathways resulting in the breakdown of cephalosporin C.