ASTER_HUMAN PAT complex subunit Asterix (sprot)

A PAT complex subunit Asterix that is encoded in the genome of human.


SYFA_HUMAN Phenylalanine--tRNA ligase alpha subunit (sprot)

A eukaryotic-type phenylalanine--tRNA ligase alpha subunit that is encoded in the genome of human.


SIGL7_HUMAN Sialic acid-binding Ig-like lectin 7 (sprot)

A sialic acid-binding Ig-like lectin 7 that is encoded in the genome of human.


ITM2B_HUMAN Integral membrane protein 2B (sprot)

An integral membrane protein 2B that is encoded in the genome of human.


SC5A6_HUMAN Sodium-dependent multivitamin transporter (sprot)

A sodium-dependent multivitamin transporter that is encoded in the genome of human.


pantothenate transmembrane transporter activity

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Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).


pantothenate transmembrane transport

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The process in which pantothenate is transported across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.


RT33_HUMAN Small ribosomal subunit protein mS33 (sprot)

A 28S ribosomal protein S33, mitochondrial that is encoded in the genome of human.


ASF1A_HUMAN Histone chaperone ASF1A (sprot)

A histone chaperone ASF1A that is encoded in the genome of human.


DRG1_HUMAN Developmentally-regulated GTP-binding protein 1 (sprot)

A developmentally-regulated GTP-binding protein 1 that is encoded in the genome of human.


TPPC4_HUMAN Trafficking protein particle complex subunit 4 (sprot)

A trafficking protein particle complex subunit 4 that is encoded in the genome of human.


FBW1A_HUMAN F-box/WD repeat-containing protein 1A (sprot)

An F-box/WD repeat-containing protein 1A that is encoded in the genome of human.


ZN443_HUMAN Zinc finger protein 443 (sprot)

A zinc finger protein 443 that is encoded in the genome of human.


NCKP1_HUMAN Nck-associated protein 1 (sprot)

A Nck-associated protein 1 that is encoded in the genome of human.


B3GN3_HUMAN N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 (sprot)

An N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 that is encoded in the genome of human.


CNPY2_HUMAN Protein canopy homolog 2 (sprot)

A protein canopy homolog 2 that is encoded in the genome of human.


RXLT1_HUMAN Ribitol-5-phosphate xylosyltransferase 1 (sprot)

A ribitol-5-phosphate xylosyltransferase 1 that is encoded in the genome of human.


Catalysis of the reaction: UDP-D-xylose + D-ribitol 5-phosphate-R = UDP + beta1,4-xylosyl-D-ribitol 5-phosphate-R.


PIGL_HUMAN N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (sprot)

An N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase that is encoded in the genome of human.


Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.


T53G5_HUMAN TP53-target gene 5 protein (sprot)

A TP53-target gene 5 protein that is encoded in the genome of human.


VP9D1_HUMAN VPS9 domain-containing protein 1 (sprot)

A VPS9 domain-containing protein 1 that is encoded in the genome of human.


IPKG_HUMAN cAMP-dependent protein kinase inhibitor gamma (sprot)

A cAMP-dependent protein kinase inhibitor gamma that is encoded in the genome of human.


UST_HUMAN Uronyl 2-sulfotransferase (sprot)

A uronyl 2-sulfotransferase that is encoded in the genome of human.


B3GT5_HUMAN Beta-1,3-galactosyltransferase 5 (sprot)

A beta-1,3-galactosyltransferase 5 that is encoded in the genome of human.


EXOG_HUMAN Nuclease EXOG, mitochondrial (sprot)

A nuclease EXOG, mitochondrial that is encoded in the genome of human.


S17A4_HUMAN Probable small intestine urate exporter (sprot)

A probable small intestine urate exporter that is encoded in the genome of human.


TLR6_HUMAN Toll-like receptor 6 (sprot)

A Toll-like receptor 6 that is encoded in the genome of human.


CAH5B_HUMAN Carbonic anhydrase 5B, mitochondrial (sprot)

A carbonic anhydrase 5B, mitochondrial that is encoded in the genome of human.


ATF5_HUMAN Cyclic AMP-dependent transcription factor ATF-5 (sprot)

A cyclic AMP-dependent transcription factor ATF-5 that is encoded in the genome of human.


S35A3_HUMAN UDP-N-acetylglucosamine transporter (sprot)

A UDP-N-acetylglucosamine transporter that is encoded in the genome of human.


EXC6B_HUMAN Exocyst complex component 6B (sprot)

An exocyst complex component 6B that is encoded in the genome of human.


AKAP2_HUMAN A-kinase anchor protein 2 (sprot)

An A-kinase anchor protein 2 that is encoded in the genome of human.


ADIP_HUMAN Afadin- and alpha-actinin-binding protein (sprot)

An afadin- and alpha-actinin-binding protein that is encoded in the genome of human.


ZN652_HUMAN Zinc finger protein 652 (sprot)

A zinc finger protein 652 that is encoded in the genome of human.


DIP2C_HUMAN Disco-interacting protein 2 homolog C (sprot)

A disco-interacting protein 2 homolog C that is encoded in the genome of human.


MA2B2_HUMAN Epididymis-specific alpha-mannosidase (sprot)

An epididymis-specific alpha-mannosidase that is encoded in the genome of human.


DTX4_HUMAN E3 ubiquitin-protein ligase DTX4 (sprot)

An E3 ubiquitin-protein ligase DTX4 that is encoded in the genome of human.


SL9A8_HUMAN Sodium/hydrogen exchanger 8 (sprot)

A sodium/hydrogen exchanger 8 that is encoded in the genome of human.


ICE1_HUMAN Little elongation complex subunit 1 (sprot)

A little elongation complex subunit 1 that is encoded in the genome of human.


BTBD3_HUMAN BTB/POZ domain-containing protein 3 (sprot)

A BTB/POZ domain-containing protein 3 that is encoded in the genome of human.


EFR3B_HUMAN Protein EFR3 homolog B (sprot)

A protein EFR3 homolog B that is encoded in the genome of human.


MYRF_HUMAN Myelin regulatory factor (sprot)

A myelin regulatory factor that is encoded in the genome of human.


CARD8_HUMAN Caspase recruitment domain-containing protein 8 (sprot)

A caspase recruitment domain-containing protein 8 that is encoded in the genome of human.


CARD8 inflammasome complex assembly

The aggregation, arrangement and bonding together of a set of components to form a CARD8 inflammasome complex.


AT11B_HUMAN Phospholipid-transporting ATPase IF (sprot)

A phospholipid-transporting ATPase IF that is encoded in the genome of human.


ANKR6_HUMAN Ankyrin repeat domain-containing protein 6 (sprot)

An ankyrin repeat domain-containing protein 6 that is encoded in the genome of human.


OFUT2_HUMAN GDP-fucose protein O-fucosyltransferase 2 (sprot)

A GDP-fucose protein O-fucosyltransferase 2 that is encoded in the genome of human.


ZFP30_HUMAN Zinc finger protein 30 homolog (sprot)

A zinc finger protein 30 homolog that is encoded in the genome of human.


DJC16_HUMAN DnaJ homolog subfamily C member 16 (sprot)

A DnaJ homolog subfamily C member 16 that is encoded in the genome of human.


SBNO2_HUMAN Protein strawberry notch homolog 2 (sprot)

A protein strawberry notch homolog 2 that is encoded in the genome of human.


cellular response to interleukin-11

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


DLGP4_HUMAN Disks large-associated protein 4 (sprot)

A disks large-associated protein 4 that is encoded in the genome of human.


ST38L_HUMAN Serine/threonine-protein kinase 38-like (sprot)

A serine/threonine-protein kinase 38-like that is encoded in the genome of human.


SAC2_HUMAN Phosphatidylinositide phosphatase SAC2 (sprot)

A phosphatidylinositide phosphatase SAC2 that is encoded in the genome of human.


PKHA6_HUMAN Pleckstrin homology domain-containing family A member 6 (sprot)

A pleckstrin homology domain-containing family A member 6 that is encoded in the genome of human.


FND3A_HUMAN Fibronectin type-III domain-containing protein 3A (sprot)

A fibronectin type-III domain-containing protein 3A that is encoded in the genome of human.


ZN510_HUMAN Zinc finger protein 510 (sprot)

A zinc finger protein 510 that is encoded in the genome of human.


MAST1_HUMAN Microtubule-associated serine/threonine-protein kinase 1 (sprot)

A microtubule-associated serine/threonine-protein kinase 1 that is encoded in the genome of human.


NISCH_HUMAN Nischarin (sprot)

A nischarin that is encoded in the genome of human.


NTNG1_HUMAN Netrin-G1 (sprot)

A netrin-G1 that is encoded in the genome of human.


NINL_HUMAN Ninein-like protein (sprot)

A ninein-like protein that is encoded in the genome of human.


FYV1_HUMAN 1-phosphatidylinositol 3-phosphate 5-kinase (sprot)

A 1-phosphatidylinositol 3-phosphate 5-kinase that is encoded in the genome of human.


1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process

The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.


WDR37_HUMAN WD repeat-containing protein 37 (sprot)

A WD repeat-containing protein 37 that is encoded in the genome of human.


TBC30_HUMAN TBC1 domain family member 30 (sprot)

A TBC1 domain family member 30 that is encoded in the genome of human.


RP3A_HUMAN Rabphilin-3A (sprot)

A rabphilin-3A that is encoded in the genome of human.


E41L3_HUMAN Band 4.1-like protein 3 (sprot)

A band 4.1-like protein 3 that is encoded in the genome of human.


AMOL2_HUMAN Angiomotin-like protein 2 (sprot)

An angiomotin-like protein 2 that is encoded in the genome of human.


PADI2_HUMAN Protein-arginine deiminase type-2 (sprot)

A protein-arginine deiminase type-2 that is encoded in the genome of human.


negative regulation of lymphocyte chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.


ZBTB1_HUMAN Zinc finger and BTB domain-containing protein 1 (sprot)

A zinc finger and BTB domain-containing protein 1 that is encoded in the genome of human.


positive regulation of pro-T cell differentiation

Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.


SIK3_HUMAN Serine/threonine-protein kinase SIK3 (sprot)

A serine/threonine-protein kinase QSK that is encoded in the genome of human.


MYH15_HUMAN Myosin-15 (sprot)

A myosin-15 that is encoded in the genome of human.


R3HD2_HUMAN R3H domain-containing protein 2 (sprot)

An R3H domain-containing protein 2 that is encoded in the genome of human.


UBP20_HUMAN Ubiquitin carboxyl-terminal hydrolase 20 (sprot)

A ubiquitin carboxyl-terminal hydrolase 20 that is encoded in the genome of human.


KDM2A_HUMAN Lysine-specific demethylase 2A (sprot)

A lysine-specific demethylase 2A that is encoded in the genome of human.


STB5L_HUMAN Syntaxin-binding protein 5-like (sprot)

A syntaxin-binding protein 5-like that is encoded in the genome of human.


RRP44_HUMAN Exosome complex exonuclease RRP44 (sprot)

An exosome complex exonuclease RRP44 that is encoded in the genome of human.


TPPC8_HUMAN Trafficking protein particle complex subunit 8 (sprot)

A trafficking protein particle complex subunit 8 that is encoded in the genome of human.


FRM4B_HUMAN FERM domain-containing protein 4B (sprot)

A FERM domain-containing protein 4B that is encoded in the genome of human.


ZKSC5_HUMAN Zinc finger protein with KRAB and SCAN domains 5 (sprot)

A zinc finger protein with KRAB and SCAN domains 5 that is encoded in the genome of human.


LRCH1_HUMAN Leucine-rich repeat and calponin homology domain-containing protein 1 (sprot)

A leucine-rich repeat and calponin homology domain-containing protein 1 that is encoded in the genome of human.


FAN1_HUMAN Fanconi-associated nuclease 1 (sprot)

A Fanconi-associated nuclease 1 that is encoded in the genome of human.


flap-structured DNA binding

Binding to a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.


SSUH2_HUMAN Protein SSUH2 homolog (sprot)

A protein SSUH2 homolog that is encoded in the genome of human.


KLH20_HUMAN Kelch-like protein 20 (sprot)

A kelch-like protein 20 that is encoded in the genome of human.


type II interferon binding

Binding to type II interferon, also known as interferon-gamma.


HIF3A_HUMAN Hypoxia-inducible factor 3-alpha (sprot)

A hypoxia-inducible factor 3-alpha that is encoded in the genome of human.


ZN835_HUMAN Zinc finger protein 835 (sprot)

A zinc finger protein 835 that is encoded in the genome of human.


S27A6_HUMAN Long-chain fatty acid transport protein 6 (sprot)

A long-chain fatty acid transport protein 6 that is encoded in the genome of human.


S27A5_HUMAN Long-chain fatty acid transport protein 5 (sprot)

A long-chain fatty acid transport protein 5 that is encoded in the genome of human.


ZN256_HUMAN Zinc finger protein 256 (sprot)

A zinc finger protein 256 that is encoded in the genome of human.


RCL1_HUMAN RNA 3'-terminal phosphate cyclase-like protein (sprot)

An RNA 3'-terminal phosphate cyclase-like protein that is encoded in the genome of human.


AT8A1_HUMAN Phospholipid-transporting ATPase IA (sprot)

A phospholipid-transporting ATPase IA that is encoded in the genome of human.


ZN257_HUMAN Zinc finger protein 257 (sprot)

A zinc finger protein 257 that is encoded in the genome of human.


GSTK1_HUMAN Glutathione S-transferase kappa 1 (sprot)

A glutathione S-transferase kappa 1 that is encoded in the genome of human.


LTOR2_HUMAN Ragulator complex protein LAMTOR2 (sprot)

A ragulator complex protein LAMTOR2 that is encoded in the genome of human.


regulation of cell-substrate junction organization

Any process that modulates the frequency, rate or extent of cell-substrate junction organization.


RT28_HUMAN Small ribosomal subunit protein bS1m (sprot)

A 28S ribosomal protein S28, mitochondrial that is encoded in the genome of human.


COA3_HUMAN Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (sprot)

A coiled-coil domain-containing protein 56 that is encoded in the genome of human.


PTN22_HUMAN Tyrosine-protein phosphatase non-receptor type 22 (sprot)

A tyrosine-protein phosphatase non-receptor type 22 that is encoded in the genome of human.


phosphoanandamide dephosphorylation

The process of removing one or more phosphate groups from a phosphorylated anandamide.


DDX52_HUMAN Probable ATP-dependent RNA helicase DDX52 (sprot)

A probable ATP-dependent RNA helicase DDX52 that is encoded in the genome of human.


RT17_HUMAN Small ribosomal subunit protein uS17m (sprot)

A 28S ribosomal protein S17, mitochondrial that is encoded in the genome of human.


RT07_HUMAN Small ribosomal subunit protein uS7m (sprot)

A 28S ribosomal protein S7, mitochondrial that is encoded in the genome of human.


CRYL1_HUMAN Lambda-crystallin homolog (sprot)

A lambda-crystallin that is encoded in the genome of human.


L-gulonate 3-dehydrogenase activity

Catalysis of the reaction: L-gulonate + NAD+ = 3-dehydro-L-gulonate + H+ + NADH.


PDIP2_HUMAN Polymerase delta-interacting protein 2 (sprot)

A polymerase delta-interacting protein 2 that is encoded in the genome of human.


AXIN2_HUMAN Axin-2 (sprot)

An Axin-2 that is encoded in the genome of human.


regulation of mismatch repair

Any process that modulates the frequency, rate or extent of mismatch repair.


regulation of chondrocyte development

Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


AP3M1_HUMAN AP-3 complex subunit mu-1 (sprot)

An AP-3 complex subunit mu-1 that is encoded in the genome of human.


GUAD_HUMAN Guanine deaminase (sprot)

A guanine deaminase that is encoded in the genome of human.


2ABG_HUMAN Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform (sprot)

A serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform that is encoded in the genome of human.


GPR52_HUMAN G-protein coupled receptor 52 (sprot)

A G-protein coupled receptor 52 that is encoded in the genome of human.


GPR55_HUMAN G-protein coupled receptor 55 (sprot)

A G-protein coupled receptor 55 that is encoded in the genome of human.


YBOX2_HUMAN Y-box-binding protein 2 (sprot)

A Y-box-binding protein 2 that is encoded in the genome of human.


KCNK7_HUMAN Potassium channel subfamily K member 7 (sprot)

A potassium channel subfamily K member 7 that is encoded in the genome of human.


M3K2_HUMAN Mitogen-activated protein kinase kinase kinase 2 (sprot)

A mitogen-activated protein kinase kinase kinase 2 that is encoded in the genome of human.


MAN1_HUMAN Inner nuclear membrane protein Man1 (sprot)

An inner nuclear membrane protein Man1 that is encoded in the genome of human.


KLDC2_HUMAN Kelch domain-containing protein 2 (sprot)

A kelch domain-containing protein 2 that is encoded in the genome of human.


CDIN1_HUMAN CDAN1-interacting nuclease 1 (sprot)

A CDAN1-interacting nuclease 1 that is encoded in the genome of human.


CHSP1_HUMAN Calcium-regulated heat-stable protein 1 (sprot)

A calcium-regulated heat-stable protein 1 that is encoded in the genome of human.


RX_HUMAN Retinal homeobox protein Rx (sprot)

A retinal homeobox protein Rx that is encoded in the genome of human.


COG6_HUMAN Conserved oligomeric Golgi complex subunit 6 (sprot)

A conserved oligomeric Golgi complex subunit 6 that is encoded in the genome of human.


TR150_HUMAN Thyroid hormone receptor-associated protein 3 (sprot)

A thyroid hormone receptor-associated protein 3 that is encoded in the genome of human.


WBP11_HUMAN WW domain-binding protein 11 (sprot)

A WW domain-binding protein 11 that is encoded in the genome of human.


S45A1_HUMAN Proton-associated sugar transporter A (sprot)

A proton-associated sugar transporter A that is encoded in the genome of human.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).


TDRKH_HUMAN Tudor and KH domain-containing protein (sprot)

A tudor and KH domain-containing protein that is encoded in the genome of human.


CSEN_HUMAN Calsenilin (sprot)

A calsenilin that is encoded in the genome of human.


MED16_HUMAN Mediator of RNA polymerase II transcription subunit 16 (sprot)

A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of human.


NOP58_HUMAN Nucleolar protein 58 (sprot)

A nucleolar protein 58 that is encoded in the genome of human.


GIT1_HUMAN ARF GTPase-activating protein GIT1 (sprot)

An ARF GTPase-activating protein GIT1 that is encoded in the genome of human.


UB2D4_HUMAN Ubiquitin-conjugating enzyme E2 D4 (sprot)

A ubiquitin-conjugating enzyme E2 D4 that is encoded in the genome of human.


ZN281_HUMAN Zinc finger protein 281 (sprot)

A zinc finger protein 281 that is encoded in the genome of human.


AR2BP_HUMAN ADP-ribosylation factor-like protein 2-binding protein (sprot)

An ADP-ribosylation factor-like protein 2-binding protein that is encoded in the genome of human.


RPC10_HUMAN DNA-directed RNA polymerase III subunit RPC10 (sprot)

A DNA-directed RNA polymerase III subunit RPC10 that is encoded in the genome of human.


ZBT32_HUMAN Zinc finger and BTB domain-containing protein 32 (sprot)

A zinc finger and BTB domain-containing protein 32 that is encoded in the genome of human.


TMM98_HUMAN Transmembrane protein 98 (sprot)

A transmembrane protein 98 that is encoded in the genome of human.


PRG3_HUMAN Proteoglycan 3 (sprot)

A proteoglycan 3 that is encoded in the genome of human.


basophil activation

The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors.


KLF13_HUMAN Krueppel-like factor 13 (sprot)

A krueppel-like factor 13 that is encoded in the genome of human.


SGT1_HUMAN Protein SGT1 homolog (sprot)

A protein SGT1 that is encoded in the genome of human.


MTO1_HUMAN Protein MTO1 homolog, mitochondrial (sprot)

A protein MTO1, mitochondrial that is encoded in the genome of human.


SYYM_HUMAN Tyrosine--tRNA ligase, mitochondrial (sprot)

A tyrosine--tRNA ligase, mitochondrial that is encoded in the genome of human.


The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


COQ6_HUMAN Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (sprot)

A ubiquinone biosynthesis monooxygenase COQ6, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.


4-hydroxy-3-all-trans-hexaprenylbenzoate + 2 H+ + O2 + 2 reduced [2Fe-2S]-[ferredoxin] = 3,4-dihydroxy-5-all-trans-hexaprenylbenzoate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin].


NAGA_HUMAN N-acetylglucosamine-6-phosphate deacetylase (sprot)

A eukaryotic-type N-acetylglucosamine-6-phosphate deacetylase that is encoded in the genome of human.


Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.


Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.


ACOT9_HUMAN Acyl-coenzyme A thioesterase 9, mitochondrial (sprot)

An acyl-coenzyme A thioesterase 9, mitochondrial that is encoded in the genome of human.


AAR2_HUMAN Protein AAR2 homolog (sprot)

A protein AAR2 homolog that is encoded in the genome of human.


NOSIP_HUMAN Nitric oxide synthase-interacting protein (sprot)

A nitric oxide synthase-interacting protein that is encoded in the genome of human.


DEOC_HUMAN Deoxyribose-phosphate aldolase (sprot)

A deoxyribose-phosphate aldolase that is encoded in the genome of human.


deoxyribose-phosphate aldolase activity

Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.


deoxyribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


deoxyribose phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.


MEMO1_HUMAN Protein MEMO1 (sprot)

A protein MEMO1 that is encoded in the genome of human.


TMX2_HUMAN Thioredoxin-related transmembrane protein 2 (sprot)

A thioredoxin-related transmembrane protein 2 that is encoded in the genome of human.


FCF1_HUMAN rRNA-processing protein FCF1 homolog (sprot)

An rRNA-processing protein FCF1 that is encoded in the genome of human.


NSG2_HUMAN Neuronal vesicle trafficking-associated protein 2 (sprot)

A neuronal vesicle trafficking-associated protein 2 that is encoded in the genome of human.


ZBT12_HUMAN Zinc finger and BTB domain-containing protein 12 (sprot)

A zinc finger and BTB domain-containing protein 12 that is encoded in the genome of human.


LSM2_HUMAN U6 snRNA-associated Sm-like protein LSm2 (sprot)

A U6 snRNA-associated Sm-like protein LSm2 that is encoded in the genome of human.


VWA7_HUMAN von Willebrand factor A domain-containing protein 7 (sprot)

A von Willebrand factor A domain-containing protein 7 that is encoded in the genome of human.


SIGL9_HUMAN Sialic acid-binding Ig-like lectin 9 (sprot)

A sialic acid-binding Ig-like lectin 9 that is encoded in the genome of human.


KLK5_HUMAN Kallikrein-5 (sprot)

A kallikrein-5 that is encoded in the genome of human.


PLLP_HUMAN Plasmolipin (sprot)

A plasmolipin that is encoded in the genome of human.


SNX24_HUMAN Sorting nexin-24 (sprot)

A sorting nexin-24 that is encoded in the genome of human.


SC6A5_HUMAN Sodium- and chloride-dependent glycine transporter 2 (sprot)

A sodium- and chloride-dependent glycine transporter 2 that is encoded in the genome of human.


STA10_HUMAN START domain-containing protein 10 (sprot)

A START domain-containing protein 10 that is encoded in the genome of human.


IFT52_HUMAN Intraflagellar transport protein 52 homolog (sprot)

An intraflagellar transport protein 52 that is encoded in the genome of human.


SHLB1_HUMAN Endophilin-B1 (sprot)

An endophilin-B1 that is encoded in the genome of human.


protein localization to vacuolar membrane

A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.


CIA30_HUMAN Complex I intermediate-associated protein 30, mitochondrial (sprot)

A complex I intermediate-associated protein 30, mitochondrial that is encoded in the genome of human.


CAB39_HUMAN Calcium-binding protein 39 (sprot)

A calcium-binding protein 39 that is encoded in the genome of human.


LC7L2_HUMAN Putative RNA-binding protein Luc7-like 2 (sprot)

A putative RNA-binding protein Luc7-like 2 that is encoded in the genome of human.


UB2J1_HUMAN Ubiquitin-conjugating enzyme E2 J1 (sprot)

A ubiquitin-conjugating enzyme E2 J1 that is encoded in the genome of human.


RBMX2_HUMAN RNA-binding motif protein, X-linked 2 (sprot)

An RNA-binding motif protein, X-linked 2 that is encoded in the genome of human.


DHRS7_HUMAN Dehydrogenase/reductase SDR family member 7 (sprot)

A dehydrogenase/reductase SDR family member 7 that is encoded in the genome of human.


ZDHC9_HUMAN Palmitoyltransferase ZDHHC9 (sprot)

A palmitoyltransferase ZDHHC9 that is encoded in the genome of human.


Ras palmitoyltransferase activity

Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.


RT02_HUMAN Small ribosomal subunit protein uS2m (sprot)

A 28S ribosomal protein S2, mitochondrial that is encoded in the genome of human.


COQ4_HUMAN Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (sprot)

A ubiquinone biosynthesis protein COQ4, mitochondrial that is encoded in the genome of human.


UTP11_HUMAN Probable U3 small nucleolar RNA-associated protein 11 (sprot)

A probable U3 small nucleolar RNA-associated protein 11 that is encoded in the genome of human.


PHOCN_HUMAN MOB-like protein phocein (sprot)

A MOB-like protein phocein that is encoded in the genome of human.


RRP7A_HUMAN Ribosomal RNA-processing protein 7 homolog A (sprot)

A ribosomal RNA-processing protein 7 homolog A that is encoded in the genome of human.


SBDS_HUMAN Ribosome maturation protein SBDS (sprot)

A ribosome maturation protein SBDS that is encoded in the genome of human.


TMED5_HUMAN Transmembrane emp24 domain-containing protein 5 (sprot)

A transmembrane emp24 domain-containing protein 5 that is encoded in the genome of human.


PLD3B_HUMAN PRELI domain containing protein 3B (sprot)

A PRELI domain containing protein 3B that is encoded in the genome of human.


EXOS1_HUMAN Exosome complex component CSL4 (sprot)

An exosome complex component CSL4 that is encoded in the genome of human.


TMED7_HUMAN Transmembrane emp24 domain-containing protein 7 (sprot)

A transmembrane emp24 domain-containing protein 7 that is encoded in the genome of human.


SF3B6_HUMAN Splicing factor 3B subunit 6 (sprot)

A splicing factor 3B subunit 6 that is encoded in the genome of human.


EMC9_HUMAN ER membrane protein complex subunit 9 (sprot)

An ER membrane protein complex subunit 9 that is encoded in the genome of human.


RM11_HUMAN Large ribosomal subunit protein uL11m (sprot)

A 39S ribosomal protein L11, mitochondrial that is encoded in the genome of human.


ORN_HUMAN Oligoribonuclease, mitochondrial (sprot)

An oligoribonuclease, mitochondrial that is encoded in the genome of human.


WASC3_HUMAN WASH complex subunit 3 (sprot)

A WASH complex subunit 3 that is encoded in the genome of human.


NOP16_HUMAN Nucleolar protein 16 (sprot)

A nucleolar protein 16 that is encoded in the genome of human.


TPRKB_HUMAN EKC/KEOPS complex subunit TPRKB (sprot)

An EKC/KEOPS complex subunit TPRKB that is encoded in the genome of human.


RNF11_HUMAN RING finger protein 11 (sprot)

A RING finger protein 11 that is encoded in the genome of human.


PPIL1_HUMAN Peptidyl-prolyl cis-trans isomerase-like 1 (sprot)

A peptidyl-prolyl cis-trans isomerase-like 1 that is encoded in the genome of human.


MED31_HUMAN Mediator of RNA polymerase II transcription subunit 31 (sprot)

A mediator of RNA polymerase II transcription subunit 31 that is encoded in the genome of human.


UFC1_HUMAN Ubiquitin-fold modifier-conjugating enzyme 1 (sprot)

A ubiquitin-fold modifier-conjugating enzyme 1 that is encoded in the genome of human.


UFM1 conjugating enzyme activity

Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y = Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.


CIA2B_HUMAN Cytosolic iron-sulfur assembly component 2B (sprot)

A cytosolic iron-sulfur assembly component 2B that is encoded in the genome of human.


MSRB2_HUMAN Methionine-R-sulfoxide reductase B2, mitochondrial (sprot)

A methionine-R-sulfoxide reductase B2, mitochondrial that is encoded in the genome of human.


RT16_HUMAN Small ribosomal subunit protein bS16m (sprot)

A 28S ribosomal protein S16, mitochondrial that is encoded in the genome of human.


RT18C_HUMAN Small ribosomal subunit protein bS18m (sprot)

A 28S ribosomal protein S18c, mitochondrial that is encoded in the genome of human.


FIS1_HUMAN Mitochondrial fission 1 protein (sprot)

A mitochondrial fission 1 protein that is encoded in the genome of human.


negative regulation of fatty acid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.


TIM16_HUMAN Mitochondrial import inner membrane translocase subunit TIM16 (sprot)

A mitochondrial import inner membrane translocase subunit Tim16 that is encoded in the genome of human.


PAM complex, Tim23 associated import motor

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the TIM23 mitochondrial import inner membrane translocase complex (GO:0005744); ATPase motor activity to drive import of proteins into the mitochondrial matrix.


KAD6_HUMAN Adenylate kinase isoenzyme 6 (sprot)

An adenylate kinase isoenzyme 6 that is encoded in the genome of human.


RT23_HUMAN Small ribosomal subunit protein mS23 (sprot)

A 28S ribosomal protein S23, mitochondrial that is encoded in the genome of human.


GOT1B_HUMAN Vesicle transport protein GOT1B (sprot)

A vesicle transport protein GOT1B that is encoded in the genome of human.


HDGR3_HUMAN Hepatoma-derived growth factor-related protein 3 (sprot)

A hepatoma-derived growth factor-related protein 3 that is encoded in the genome of human.


BOLA1_HUMAN BolA-like protein 1 (sprot)

A BolA-like protein 1 that is encoded in the genome of human.


PTH2_HUMAN Peptidyl-tRNA hydrolase 2, mitochondrial (sprot)

A peptidyl-tRNA hydrolase 2, mitochondrial that is encoded in the genome of human.


CHMP3_HUMAN Charged multivesicular body protein 3 (sprot)

A charged multivesicular body protein 3 that is encoded in the genome of human.


STRAP_HUMAN Serine-threonine kinase receptor-associated protein (sprot)

A serine-threonine kinase receptor-associated protein that is encoded in the genome of human.


RTCB_HUMAN RNA-splicing ligase RtcB homolog (sprot)

An RNA-splicing ligase RtcB that is encoded in the genome of human.


FBX7_HUMAN F-box only protein 7 (sprot)

An F-box only protein 7 that is encoded in the genome of human.


negative regulation of lymphocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.


glial cytoplasmic inclusion

Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.


classical Lewy body

Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.


Lewy neurite

Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.


Lewy body corona

The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.


3BP1_HUMAN SH3 domain-binding protein 1 (sprot)

An SH3 domain-binding protein 1 that is encoded in the genome of human.


RAP2C_HUMAN Ras-related protein Rap-2c (sprot)

A Ras-related protein Rap-2c that is encoded in the genome of human.


CBY1_HUMAN Protein chibby homolog 1 (sprot)

A protein chibby homolog 1 that is encoded in the genome of human.


STA13_HUMAN StAR-related lipid transfer protein 13 (sprot)

A StAR-related lipid transfer protein 13 that is encoded in the genome of human.


ZN337_HUMAN Zinc finger protein 337 (sprot)

A zinc finger protein 337 that is encoded in the genome of human.


OR2W1_HUMAN Olfactory receptor 2W1 (sprot)

An olfactory receptor 2W1 that is encoded in the genome of human.


RHBD3_HUMAN Rhomboid domain-containing protein 3 (sprot)

A rhomboid domain-containing protein 3 that is encoded in the genome of human.


SIT1_HUMAN Signaling threshold-regulating transmembrane adapter 1 (sprot)

A signaling threshold-regulating transmembrane adapter 1 that is encoded in the genome of human.


RBGP1_HUMAN Rab GTPase-activating protein 1 (sprot)

A Rab GTPase-activating protein 1 that is encoded in the genome of human.


NALD2_HUMAN N-acetylated-alpha-linked acidic dipeptidase 2 (sprot)

An N-acetylated-alpha-linked acidic dipeptidase 2 that is encoded in the genome of human.


TMED3_HUMAN Transmembrane emp24 domain-containing protein 3 (sprot)

A transmembrane emp24 domain-containing protein 3 that is encoded in the genome of human.


HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 that is encoded in the genome of human.


voltage-gated potassium channel activity involved in SA node cell action potential depolarization

Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


ADA18_HUMAN Disintegrin and metalloproteinase domain-containing protein 18 (sprot)

A disintegrin and metalloproteinase domain-containing protein 18 that is encoded in the genome of human.


T22D4_HUMAN TSC22 domain family protein 4 (sprot)

A TSC22 domain family protein 4 that is encoded in the genome of human.


GRIP1_HUMAN Glutamate receptor-interacting protein 1 (sprot)

A glutamate receptor-interacting protein 1 that is encoded in the genome of human.


NEUR2_HUMAN Sialidase-2 (sprot)

A sialidase-2 that is encoded in the genome of human.


DOP2_HUMAN Protein dopey-2 (sprot)

A protein dopey-2 that is encoded in the genome of human.


WNK2_HUMAN Serine/threonine-protein kinase WNK2 (sprot)

A serine/threonine-protein kinase WNK2 that is encoded in the genome of human.


ZN330_HUMAN Zinc finger protein 330 (sprot)

A zinc finger protein 330 that is encoded in the genome of human.


R3HC1_HUMAN R3H and coiled-coil domain-containing protein 1 (sprot)

An R3H and coiled-coil domain-containing protein 1 that is encoded in the genome of human.


NOC2L_HUMAN Nucleolar complex protein 2 homolog (sprot)

A nucleolar complex protein 2 that is encoded in the genome of human.


RL36_HUMAN Large ribosomal subunit protein eL36 (sprot)

A 60S ribosomal protein L36 that is encoded in the genome of human.


RWDD3_HUMAN RWD domain-containing protein 3 (sprot)

An RWD domain-containing protein 3 that is encoded in the genome of human.


positive regulation of hypoxia-inducible factor-1alpha signaling pathway

Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.


CCDC9_HUMAN Coiled-coil domain-containing protein 9 (sprot)

A coiled-coil domain-containing protein 9 that is encoded in the genome of human.


CHTOP_HUMAN Chromatin target of PRMT1 protein (sprot)

A chromatin target of PRMT1 protein that is encoded in the genome of human.


PYGO1_HUMAN Pygopus homolog 1 (sprot)

A pygopus homolog 1 that is encoded in the genome of human.


SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (sprot)

A deoxynucleoside triphosphate triphosphohydrolase SAMHD1 that is encoded in the genome of human.


dGTPase activity

Catalysis of the reaction: dGTP + H2O = 2'-deoxyguanosine + 2 H+ + triphosphate.


triphosphoric monoester hydrolase activity

Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.


dGTP binding

Binding to dGTP, deoxyguanosine triphosphate.


deoxynucleoside triphosphate hydrolase activity

Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate.


deoxyribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


FA32A_HUMAN Protein FAM32A (sprot)

A protein FAM32A that is encoded in the genome of human.


C2CD2_HUMAN C2 domain-containing protein 2 (sprot)

A C2 domain-containing protein 2 that is encoded in the genome of human.


CV024_HUMAN Putative uncharacterized protein YWHAH-AS1 (sprot)


PKP3_HUMAN Plakophilin-3 (sprot)

A plakophilin-3 that is encoded in the genome of human.


SKAP_HUMAN Small kinetochore-associated protein (sprot)

A small kinetochore-associated protein that is encoded in the genome of human.


HBS1L_HUMAN HBS1-like protein (sprot)

An HBS1-like protein that is encoded in the genome of human.


TBX22_HUMAN T-box transcription factor TBX22 (sprot)

A T-box transcription factor TBX22 that is encoded in the genome of human.


ZN711_HUMAN Zinc finger protein 711 (sprot)

A zinc finger protein 711 that is encoded in the genome of human.


DYR1B_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1B (sprot)

A dual specificity tyrosine-phosphorylation-regulated kinase 1B that is encoded in the genome of human.


NR2E1_HUMAN Nuclear receptor subfamily 2 group E member 1 (sprot)

A nuclear receptor subfamily 2 group E member 1 that is encoded in the genome of human.


forebrain generation of neurons

The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.


SALL2_HUMAN Sal-like protein 2 (sprot)

A Sal-like protein 2 that is encoded in the genome of human.


LMBL1_HUMAN Lethal(3)malignant brain tumor-like protein 1 (sprot)

A lethal(3)malignant brain tumor-like protein 1 that is encoded in the genome of human.


SAM domain binding

Binding to a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.


CMAH_HUMAN Inactive cytidine monophosphate-N-acetylneuraminic acid hydroxylase (sprot)

A protein that is a translation product of the CMAHP gene in human.


Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.


ZN175_HUMAN Zinc finger protein 175 (sprot)

A zinc finger protein 175 that is encoded in the genome of human.


AAKB1_HUMAN 5'-AMP-activated protein kinase subunit beta-1 (sprot)

A 5'-AMP-activated protein kinase subunit beta-1 that is encoded in the genome of human.


MTF2_HUMAN Metal-response element-binding transcription factor 2 (sprot)

A metal-response element-binding transcription factor 2 that is encoded in the genome of human.


WIPI4_HUMAN WD repeat domain phosphoinositide-interacting protein 4 (sprot)

A WD repeat domain phosphoinositide-interacting protein 4 that is encoded in the genome of human.


VPP2_HUMAN V-type proton ATPase 116 kDa subunit a 2 (sprot)

A V-type proton ATPase 116 kDa subunit a 2 that is encoded in the genome of human.


TLN1_HUMAN Talin-1 (sprot)

A talin-1 that is encoded in the genome of human.


ZAN_HUMAN Zonadhesin (sprot)

A zonadhesin that is encoded in the genome of human.


KIF3A_HUMAN Kinesin-like protein KIF3A (sprot)

A kinesin-like protein KIF3A that is encoded in the genome of human.


JERKL_HUMAN Jerky protein homolog-like (sprot)

A jerky protein homolog-like that is encoded in the genome of human.


TRRAP_HUMAN Transformation/transcription domain-associated protein (sprot)

A transformation/transcription domain-associated protein that is encoded in the genome of human.


NF2L3_HUMAN Nuclear factor erythroid 2-related factor 3 (sprot)

A nuclear factor erythroid 2-related factor 3 that is encoded in the genome of human.


O10H1_HUMAN Olfactory receptor 10H1 (sprot)

An olfactory receptor 10H1 that is encoded in the genome of human.


ARIP4_HUMAN Helicase ARIP4 (sprot)

A helicase ARIP4 that is encoded in the genome of human.


MTCL1_HUMAN Microtubule cross-linking factor 1 (sprot)

A microtubule cross-linking factor 1 that is encoded in the genome of human.


DCAF1_HUMAN DDB1- and CUL4-associated factor 1 (sprot)

A DDB1- and CUL4-associated factor 1 that is encoded in the genome of human.


histone H2AT120 kinase activity

Catalysis of the reaction: histone H2A-threonine (position 120) + ATP = histone H2A-phosphothreonine (position 120) + ADP. This reaction is the addition of a phosphate group to the threonine residue at position 120 of histone H2A.


cell competition in a multicellular organism

Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.


NRX3A_HUMAN Neurexin-3 (sprot)

A neurexin-3-alpha that is encoded in the genome of human.


KDM3A_HUMAN Lysine-specific demethylase 3A (sprot)

A lysine-specific demethylase 3A that is encoded in the genome of human.


formaldehyde biosynthetic process

The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.


TCAF1_HUMAN TRPM8 channel-associated factor 1 (sprot)

A TRPM8 channel-associated factor 1 that is encoded in the genome of human.


MFHA1_HUMAN Malignant fibrous histiocytoma-amplified sequence 1 (sprot)

A malignant fibrous histiocytoma-amplified sequence 1 that is encoded in the genome of human.


CHST2_HUMAN Carbohydrate sulfotransferase 2 (sprot)

A carbohydrate sulfotransferase 2 that is encoded in the genome of human.


RBM19_HUMAN Probable RNA-binding protein 19 (sprot)

A probable RNA-binding protein 19 that is encoded in the genome of human.


DAAM1_HUMAN Disheveled-associated activator of morphogenesis 1 (sprot)

A disheveled-associated activator of morphogenesis 1 that is encoded in the genome of human.


DGLA_HUMAN Diacylglycerol lipase-alpha (sprot)

A diacylglycerol lipase-alpha that is encoded in the genome of human.


PLXD1_HUMAN Plexin-D1 (sprot)

A plexin-D1 that is encoded in the genome of human.


synaptic target recognition

The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.


HECD4_HUMAN Probable E3 ubiquitin-protein ligase HECTD4 (sprot)

A probable E3 ubiquitin-protein ligase HECTD4 that is encoded in the genome of human.


WAC2C_HUMAN WASH complex subunit 2C (sprot)

A WASH complex subunit 2C that is encoded in the genome of human.


ZN451_HUMAN E3 SUMO-protein ligase ZNF451 (sprot)

An E3 SUMO-protein ligase ZNF451 that is encoded in the genome of human.


WDR7_HUMAN WD repeat-containing protein 7 (sprot)

A WD repeat-containing protein 7 that is encoded in the genome of human.


UBP15_HUMAN Ubiquitin carboxyl-terminal hydrolase 15 (sprot)

A ubiquitin carboxyl-terminal hydrolase 15 that is encoded in the genome of human.


FARP1_HUMAN FERM, ARHGEF and pleckstrin domain-containing protein 1 (sprot)

A FERM, ARHGEF and pleckstrin domain-containing protein 1 that is encoded in the genome of human.


MARF1_HUMAN Meiosis regulator and mRNA stability factor 1 (sprot)

A meiosis regulator and mRNA stability factor 1 that is encoded in the genome of human.


TGRM1_HUMAN TOG array regulator of axonemal microtubules protein 1 (sprot)

A TOG array regulator of axonemal microtubules protein 1 that is encoded in the genome of human.


C170B_HUMAN Centrosomal protein of 170 kDa protein B (sprot)

A centrosomal protein of 170 kDa protein B that is encoded in the genome of human.


RIPR2_HUMAN Rho family-interacting cell polarization regulator 2 (sprot)

A Rho family-interacting cell polarization regulator 2 that is encoded in the genome of human.


negative regulation of establishment of T cell polarity

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.


negative regulation of protein localization to cell leading edge

Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge.


negative regulation of Rho guanyl-nucleotide exchange factor activity

Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.


PKHM1_HUMAN Pleckstrin homology domain-containing family M member 1 (sprot)

A pleckstrin homology domain-containing family M member 1 that is encoded in the genome of human.


TLN2_HUMAN Talin-2 (sprot)

A talin-2 that is encoded in the genome of human.


RPGF2_HUMAN Rap guanine nucleotide exchange factor 2 (sprot)

A Rap guanine nucleotide exchange factor 2 that is encoded in the genome of human.


IRS2_HUMAN Insulin receptor substrate 2 (sprot)

An insulin receptor substrate 2 that is encoded in the genome of human.


GPSM3_HUMAN G-protein-signaling modulator 3 (sprot)

A G-protein-signaling modulator 3 that is encoded in the genome of human.


MYO5A_HUMAN Unconventional myosin-Va (sprot)

A myosin-Va that is encoded in the genome of human.


MTL5_HUMAN Tesmin (sprot)

A tesmin that is encoded in the genome of human.


DTNA_HUMAN Dystrobrevin alpha (sprot)

A dystrobrevin alpha that is encoded in the genome of human.


LOXL2_HUMAN Lysyl oxidase homolog 2 (sprot)

A lysyl oxidase homolog 2 that is encoded in the genome of human.


CRBG1_HUMAN Beta/gamma crystallin domain-containing protein 1 (sprot)

A beta/gamma crystallin domain-containing protein 1 that is encoded in the genome of human.


TRAF6_HUMAN TNF receptor-associated factor 6 (sprot)

A TNF receptor-associated factor 6 that is encoded in the genome of human.


M4K5_HUMAN Mitogen-activated protein kinase kinase kinase kinase 5 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 5 that is encoded in the genome of human.


HYOU1_HUMAN Hypoxia up-regulated protein 1 (sprot)

A hypoxia up-regulated protein 1 that is encoded in the genome of human.


RN115_HUMAN E3 ubiquitin-protein ligase RNF115 (sprot)

An E3 ubiquitin-protein ligase RNF115 that is encoded in the genome of human.


CH071_HUMAN Putative uncharacterized protein encoded by LINC00588 (sprot)


ATG4B_HUMAN Cysteine protease ATG4B (sprot)

A cysteine protease ATG4B that is encoded in the genome of human.


otolith mineralization completed early in development

The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear.


TBL2_HUMAN Transducin beta-like protein 2 (sprot)

A transducin beta-like protein 2 that is encoded in the genome of human.


WIPI2_HUMAN WD repeat domain phosphoinositide-interacting protein 2 (sprot)

A WD repeat domain phosphoinositide-interacting protein 2 that is encoded in the genome of human.


SPEF1_HUMAN Sperm flagellar protein 1 (sprot)

A sperm flagellar protein 1 that is encoded in the genome of human.


TTLL3_HUMAN Tubulin monoglycylase TTLL3 (sprot)

A tubulin monoglycylase TTLL3 that is encoded in the genome of human.


TELO2_HUMAN Telomere length regulation protein TEL2 homolog (sprot)

A telomere length regulation protein TEL2 that is encoded in the genome of human.


MMAC_HUMAN Cyanocobalamin reductase / alkylcobalamin dealkylase (sprot)

A cyanocobalamin reductase / alkylcobalamin dealkylase that is encoded in the genome of human.


cyanocobalamin reductase (cyanide-eliminating) activity

Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP+ = cyanocob(III)alamin + H+ + NADPH.


demethylation

The process of removing one or more methyl groups from a molecule.


LAS1L_HUMAN Ribosomal biogenesis protein LAS1L (sprot)

A LAS1-like protein that is encoded in the genome of human.


Las1 complex

A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).


AFG32_HUMAN AFG3-like protein 2 (sprot)

An AFG3-like protein 2 that is encoded in the genome of human.


AMMR1_HUMAN Nuclear protein AMMECR1 (sprot)

A nuclear protein AMMECR1 that is encoded in the genome of human.


CCL27_HUMAN C-C motif chemokine 27 (sprot)

A C-C motif chemokine 27 that is encoded in the genome of human.


KLF12_HUMAN Krueppel-like factor 12 (sprot)

A krueppel-like factor 12 that is encoded in the genome of human.


ARI1_HUMAN E3 ubiquitin-protein ligase ARIH1 (sprot)

An E3 ubiquitin-protein ligase ARIH1 that is encoded in the genome of human.


LSM5_HUMAN U6 snRNA-associated Sm-like protein LSm5 (sprot)

A U6 snRNA-associated Sm-like protein LSm5 that is encoded in the genome of human.


LSM4_HUMAN U6 snRNA-associated Sm-like protein LSm4 (sprot)

A U6 snRNA-associated Sm-like protein LSm4 that is encoded in the genome of human.


NGN3_HUMAN Neurogenin-3 (sprot)

A neurogenin-3 that is encoded in the genome of human.


RN114_HUMAN E3 ubiquitin-protein ligase RNF114 (sprot)

An E3 ubiquitin-protein ligase RNF114 that is encoded in the genome of human.


SAM50_HUMAN Sorting and assembly machinery component 50 homolog (sprot)

A sorting and assembly machinery component 50 that is encoded in the genome of human.


T184B_HUMAN Transmembrane protein 184B (sprot)

A transmembrane protein 184B that is encoded in the genome of human.


PRC2C_HUMAN Protein PRRC2C (sprot)

A protein PRRC2C that is encoded in the genome of human.


OARD1_HUMAN ADP-ribose glycohydrolase OARD1 (sprot)

An ADP-ribose glycohydrolase OARD1 that is encoded in the genome of human.


CSDC2_HUMAN Cold shock domain-containing protein C2 (sprot)

A cold shock domain-containing protein C2 that is encoded in the genome of human.


RPC8_HUMAN DNA-directed RNA polymerase III subunit RPC8 (sprot)

A DNA-directed RNA polymerase III subunit RPC8 that is encoded in the genome of human.


PAL4A_HUMAN Peptidyl-prolyl cis-trans isomerase A-like 4A (sprot)

A protein that is a translation product of the PPIAL4A gene in human.


HES2_HUMAN Transcription factor HES-2 (sprot)

A transcription factor HES-2 that is encoded in the genome of human.


IFT25_HUMAN Intraflagellar transport protein 25 homolog (sprot)

An intraflagellar transport protein 25 homolog that is encoded in the genome of human.


YIPF1_HUMAN Protein YIPF1 (sprot)

A protein YIPF1 that is encoded in the genome of human.


LRP12_HUMAN Low-density lipoprotein receptor-related protein 12 (sprot)

A low-density lipoprotein receptor-related protein 12 that is encoded in the genome of human.


SHAN1_HUMAN SH3 and multiple ankyrin repeat domains protein 1 (sprot)

An SH3 and multiple ankyrin repeat domains protein 1 that is encoded in the genome of human.


somatostatin receptor binding

Binding to a somatostatin receptor.


determination of affect

Any process in which an emotional response is associated with a particular sensory stimulation.


PPME1_HUMAN Protein phosphatase methylesterase 1 (sprot)

A protein phosphatase methylesterase 1 that is encoded in the genome of human.


protein C-terminal methylesterase activity

Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.


RIPK3_HUMAN Receptor-interacting serine/threonine-protein kinase 3 (sprot)

A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human.


regulation of activation-induced cell death of T cells

Any process that modulates the occurrence or rate of activation-induced cell death of T cells.


regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.


IPP_HUMAN Actin-binding protein IPP (sprot)

An actin-binding protein IPP that is encoded in the genome of human.


ASB4_HUMAN Ankyrin repeat and SOCS box protein 4 (sprot)

An ankyrin repeat and SOCS box protein 4 that is encoded in the genome of human.


ASB3_HUMAN Ankyrin repeat and SOCS box protein 3 (sprot)

An ankyrin repeat and SOCS box protein 3 that is encoded in the genome of human.


ASB1_HUMAN Ankyrin repeat and SOCS box protein 1 (sprot)

An ankyrin repeat and SOCS box protein 1 that is encoded in the genome of human.


TRI17_HUMAN E3 ubiquitin-protein ligase TRIM17 (sprot)

An E3 ubiquitin-protein ligase TRIM17 that is encoded in the genome of human.


RBM7_HUMAN RNA-binding protein 7 (sprot)

An RNA-binding protein 7 that is encoded in the genome of human.


INSL6_HUMAN Insulin-like peptide INSL6 (sprot)

An insulin-like peptide INSL6 that is encoded in the genome of human.


TIM22_HUMAN Mitochondrial import inner membrane translocase subunit Tim22 (sprot)

A mitochondrial import inner membrane translocase subunit Tim22 that is encoded in the genome of human.


OR1A2_HUMAN Olfactory receptor 1A2 (sprot)

An olfactory receptor 1A2 that is encoded in the genome of human.


MB212_HUMAN Protein mab-21-like 2 (sprot)

A protein mab-21-like 2 that is encoded in the genome of human.


AP4S1_HUMAN AP-4 complex subunit sigma-1 (sprot)

An AP-4 complex subunit sigma-1 that is encoded in the genome of human.


CEP83_HUMAN Centrosomal protein of 83 kDa (sprot)

A centrosomal protein of 83 kDa that is encoded in the genome of human.


KCTD3_HUMAN BTB/POZ domain-containing protein KCTD3 (sprot)

A BTB/POZ domain-containing protein KCTD3 that is encoded in the genome of human.


ZSC21_HUMAN Zinc finger and SCAN domain-containing protein 21 (sprot)

A zinc finger and SCAN domain-containing protein 21 that is encoded in the genome of human.


NUB1_HUMAN NEDD8 ultimate buster 1 (sprot)

A NEDD8 ultimate buster 1 that is encoded in the genome of human.


YTHD2_HUMAN YTH domain-containing family protein 2 (sprot)

A YTH domain-containing family protein 2 that is encoded in the genome of human.


CTDP1_HUMAN RNA polymerase II subunit A C-terminal domain phosphatase (sprot)

An RNA polymerase II subunit A C-terminal domain phosphatase that is encoded in the genome of human.


TFIIF-class transcription factor complex binding

Binding to a general RNA polymerase II transcription factor belonging to the TFIIF complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.


PAXB1_HUMAN PAX3- and PAX7-binding protein 1 (sprot)

A PAX3- and PAX7-binding protein 1 that is encoded in the genome of human.


NDK7_HUMAN Nucleoside diphosphate kinase 7 (sprot)

A nucleoside diphosphate kinase 7 that is encoded in the genome of human.


SP16H_HUMAN FACT complex subunit SPT16 (sprot)

A FACT complex subunit SPT16 that is encoded in the genome of human.


ANGL3_HUMAN Angiopoietin-related protein 3 (sprot)

An angiopoietin-related protein 3 that is encoded in the genome of human.


PCDB9_HUMAN Protocadherin beta-9 (sprot)

A protocadherin beta-9 that is encoded in the genome of human.


PCDB7_HUMAN Protocadherin beta-7 (sprot)

A protocadherin beta-7 that is encoded in the genome of human.


PCDB6_HUMAN Protocadherin beta-6 (sprot)

A protocadherin beta-6 that is encoded in the genome of human.


PCDB5_HUMAN Protocadherin beta-5 (sprot)

A protocadherin beta-5 that is encoded in the genome of human.


PCDB4_HUMAN Protocadherin beta-4 (sprot)

A protocadherin beta-4 that is encoded in the genome of human.


PCDB3_HUMAN Protocadherin beta-3 (sprot)

A protocadherin beta-3 that is encoded in the genome of human.


PCDB2_HUMAN Protocadherin beta-2 (sprot)

A protocadherin beta-2 that is encoded in the genome of human.


PCDBF_HUMAN Protocadherin beta-15 (sprot)

A protocadherin beta-15 that is encoded in the genome of human.


PCDBE_HUMAN Protocadherin beta-14 (sprot)

A protocadherin beta-14 that is encoded in the genome of human.


PCDBD_HUMAN Protocadherin beta-13 (sprot)

A protocadherin beta-13 that is encoded in the genome of human.


PCDBC_HUMAN Protocadherin beta-12 (sprot)

A protocadherin beta-12 that is encoded in the genome of human.


PCDBB_HUMAN Protocadherin beta-11 (sprot)

A protocadherin beta-11 that is encoded in the genome of human.


PCDB1_HUMAN Protocadherin beta-1 (sprot)

A protocadherin beta-1 that is encoded in the genome of human.


PCDGM_HUMAN Protocadherin gamma-C5 (sprot)

A protocadherin gamma-C5 that is encoded in the genome of human.


PCDGL_HUMAN Protocadherin gamma-C4 (sprot)

A protocadherin gamma-C4 that is encoded in the genome of human.


PCDGJ_HUMAN Protocadherin gamma-B7 (sprot)

A protocadherin gamma-B7 that is encoded in the genome of human.


PCDGI_HUMAN Protocadherin gamma-B6 (sprot)

A protocadherin gamma-B6 that is encoded in the genome of human.


PCDGH_HUMAN Protocadherin gamma-B5 (sprot)

A protocadherin gamma-B5 that is encoded in the genome of human.


PCDGF_HUMAN Protocadherin gamma-B3 (sprot)

A protocadherin gamma-B3 that is encoded in the genome of human.


PCDGE_HUMAN Protocadherin gamma-B2 (sprot)

A protocadherin gamma-B2 that is encoded in the genome of human.


PCDGD_HUMAN Protocadherin gamma-B1 (sprot)

A protocadherin gamma-B1 that is encoded in the genome of human.


PCDG9_HUMAN Protocadherin gamma-A9 (sprot)

A protocadherin gamma-A9 that is encoded in the genome of human.


PCDG8_HUMAN Protocadherin gamma-A8 (sprot)

A protocadherin gamma-A8 that is encoded in the genome of human.


PCDG7_HUMAN Protocadherin gamma-A7 (sprot)

A protocadherin gamma-A7 that is encoded in the genome of human.


PCDG6_HUMAN Protocadherin gamma-A6 (sprot)

A protocadherin gamma-A6 that is encoded in the genome of human.


PCDG5_HUMAN Protocadherin gamma-A5 (sprot)

A protocadherin gamma-A5 that is encoded in the genome of human.


PCDG4_HUMAN Protocadherin gamma-A4 (sprot)

A protocadherin gamma-A4 that is encoded in the genome of human.


PCDG3_HUMAN Protocadherin gamma-A3 (sprot)

A protocadherin gamma-A3 that is encoded in the genome of human.


lipid tube assembly involved in organelle fusion

The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.


PCDG2_HUMAN Protocadherin gamma-A2 (sprot)

A protocadherin gamma-A2 that is encoded in the genome of human.


PCDGB_HUMAN Protocadherin gamma-A11 (sprot)

A protocadherin gamma-A11 that is encoded in the genome of human.


PCDGA_HUMAN Protocadherin gamma-A10 (sprot)

A protocadherin gamma-A10 that is encoded in the genome of human.


PCDG1_HUMAN Protocadherin gamma-A1 (sprot)

A protocadherin gamma-A1 that is encoded in the genome of human.


PCDA9_HUMAN Protocadherin alpha-9 (sprot)

A protocadherin alpha-9 that is encoded in the genome of human.


PCDA8_HUMAN Protocadherin alpha-8 (sprot)

A protocadherin alpha-8 that is encoded in the genome of human.


PCDA5_HUMAN Protocadherin alpha-5 (sprot)

A protocadherin alpha-5 that is encoded in the genome of human.


PCDA3_HUMAN Protocadherin alpha-3 (sprot)

A protocadherin alpha-3 that is encoded in the genome of human.


PCDA2_HUMAN Protocadherin alpha-2 (sprot)

A protocadherin alpha-2 that is encoded in the genome of human.


PCDAD_HUMAN Protocadherin alpha-13 (sprot)

A protocadherin alpha-13 that is encoded in the genome of human.


PCDAB_HUMAN Protocadherin alpha-11 (sprot)

A protocadherin alpha-11 that is encoded in the genome of human.


PCDAA_HUMAN Protocadherin alpha-10 (sprot)

A protocadherin alpha-10 that is encoded in the genome of human.


PCDA1_HUMAN Protocadherin alpha-1 (sprot)

A protocadherin alpha-1 that is encoded in the genome of human.


PCDC2_HUMAN Protocadherin alpha-C2 (sprot)

A protocadherin alpha-C2 that is encoded in the genome of human.


CLD16_HUMAN Claudin-16 (sprot)

A claudin-16 that is encoded in the genome of human.


intercellular transport

The movement of substances between cells.


UTP18_HUMAN U3 small nucleolar RNA-associated protein 18 homolog (sprot)

A U3 small nucleolar RNA-associated protein 18 that is encoded in the genome of human.


HEY1_HUMAN Hairy/enhancer-of-split related with YRPW motif protein 1 (sprot)

A hairy/enhancer-of-split related with YRPW motif protein 1 that is encoded in the genome of human.


PHLA3_HUMAN Pleckstrin homology-like domain family A member 3 (sprot)

A pleckstrin homology-like domain family A member 3 that is encoded in the genome of human.


T10B_HUMAN Mitochondrial import inner membrane translocase subunit Tim10 B (sprot)

A mitochondrial import inner membrane translocase subunit Tim9 B that is encoded in the genome of human.


TIM9_HUMAN Mitochondrial import inner membrane translocase subunit Tim9 (sprot)

A mitochondrial import inner membrane translocase subunit Tim9 that is encoded in the genome of human.


TIM8B_HUMAN Mitochondrial import inner membrane translocase subunit Tim8 B (sprot)

A mitochondrial import inner membrane translocase subunit Tim8 B that is encoded in the genome of human.


SPO11_HUMAN Meiotic recombination protein SPO11 (sprot)

A meiotic recombination protein SPO11 that is encoded in the genome of human.


KLK4_HUMAN Kallikrein-4 (sprot)

A kallikrein-4 that is encoded in the genome of human.


PCY1B_HUMAN Choline-phosphate cytidylyltransferase B (sprot)

A choline-phosphate cytidylyltransferase B that is encoded in the genome of human.


UCHL5_HUMAN Ubiquitin carboxyl-terminal hydrolase isozyme L5 (sprot)

A ubiquitin carboxyl-terminal hydrolase isozyme L5 that is encoded in the genome of human.


CD2AP_HUMAN CD2-associated protein (sprot)

A CD2-associated protein that is encoded in the genome of human.


VATD_HUMAN V-type proton ATPase subunit D (sprot)

A V-type proton ATPase subunit D that is encoded in the genome of human.


TNPO3_HUMAN Transportin-3 (sprot)

A transportin-3 that is encoded in the genome of human.


HLPDA_HUMAN Hypoxia-inducible lipid droplet-associated protein (sprot)

A hypoxia-inducible lipid droplet-associated protein that is encoded in the genome of human.


ENTP2_HUMAN Ectonucleoside triphosphate diphosphohydrolase 2 (sprot)

An ectonucleoside triphosphate diphosphohydrolase 2 that is encoded in the genome of human.


purine ribonucleoside diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.


TIM13_HUMAN Mitochondrial import inner membrane translocase subunit Tim13 (sprot)

A mitochondrial import inner membrane translocase subunit Tim13 that is encoded in the genome of human.


LENEP_HUMAN Lens epithelial cell protein LEP503 (sprot)

A lens epithelial cell protein LEP503 that is encoded in the genome of human.


F215A_HUMAN Uncharacterized protein FAM215A (sprot)

An apoptosis-related protein 2 that is encoded in the genome of human.


SRPRB_HUMAN Signal recognition particle receptor subunit beta (sprot)

A signal recognition particle receptor subunit beta that is encoded in the genome of human.


HRH3_HUMAN Histamine H3 receptor (sprot)

A histamine H3 receptor that is encoded in the genome of human.


N6MT1_HUMAN Methyltransferase N6AMT1 (sprot)

A methyltransferase N6AMT1 that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.


histone H4K12 methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 12) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 12). This reaction is the addition of a methyl group to the lysine residue at position 12 of the histone H4 protein.


ORC6_HUMAN Origin recognition complex subunit 6 (sprot)

An origin recognition complex subunit 6 that is encoded in the genome of human.


O51B4_HUMAN Olfactory receptor 51B4 (sprot)

An olfactory receptor 51B4 that is encoded in the genome of human.


O51B2_HUMAN Olfactory receptor 51B2 (sprot)

An olfactory receptor 51B2 that is encoded in the genome of human.


CSAG2_HUMAN Chondrosarcoma-associated gene 2/3 protein (sprot)

A chondrosarcoma-associated gene 2/3A protein that is encoded in the genome of human.


RAI2_HUMAN Retinoic acid-induced protein 2 (sprot)

A retinoic acid-induced protein 2 that is encoded in the genome of human.


CERT_HUMAN Ceramide transfer protein (sprot)

A ceramide transfer protein that is encoded in the genome of human.


ceramide transfer activity

Removes a ceramide from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


intermembrane sphingolipid transfer

The transport of sphingolipids between membranes in which a sphingolipid molecule is transported through an aqueous phase from the outer leaflet of a donor membrane to the outer leaflet of an acceptor membrane. This process does not require metabolic energy and can be either spontaneous or mediated by lipid transfer proteins (LTPs).


GMPPB_HUMAN Mannose-1-phosphate guanyltransferase beta (sprot)

A mannose-1-phosphate guanyltransferase beta that is encoded in the genome of human.


P2R3B_HUMAN Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (sprot)

A serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta that is encoded in the genome of human.


FADS3_HUMAN Fatty acid desaturase 3 (sprot)

A fatty acid desaturase 3 that is encoded in the genome of human.


MAFB_HUMAN Transcription factor MafB (sprot)

A transcription factor MafB that is encoded in the genome of human.


rhombomere 6 development

The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


CORIN_HUMAN Atrial natriuretic peptide-converting enzyme (sprot)

An atrial natriuretic peptide-converting enzyme that is encoded in the genome of human.


INSL5_HUMAN Insulin-like peptide INSL5 (sprot)

An insulin-like peptide INSL5 that is encoded in the genome of human.


TF3C5_HUMAN General transcription factor 3C polypeptide 5 (sprot)

A general transcription factor 3C polypeptide 5 that is encoded in the genome of human.


TF3C3_HUMAN General transcription factor 3C polypeptide 3 (sprot)

A general transcription factor 3C polypeptide 3 that is encoded in the genome of human.


MMP24_HUMAN Matrix metalloproteinase-24 (sprot)

A matrix metalloproteinase-24 that is encoded in the genome of human.


HEMK1_HUMAN MTRF1L release factor glutamine methyltransferase (sprot)

An MTRF1L release factor glutamine methyltransferase that is encoded in the genome of human.


Catalysis of the reaction: S-adenosyl-L-methionine + a [release factor]-L-glutamine = S-adenosyl-L-homocysteine + H+ + a [release factor]-N5-methyl-L-glutamine.


DMRT2_HUMAN Doublesex- and mab-3-related transcription factor 2 (sprot)

A doublesex- and mab-3-related transcription factor 2 that is encoded in the genome of human.


positive regulation of myotome development

Any process that activates or increases the frequency, rate or extent of myotome development.


DMRT1_HUMAN Doublesex- and mab-3-related transcription factor 1 (sprot)

A doublesex- and mab-3-related transcription factor 1 that is encoded in the genome of human.


TPPC1_HUMAN Trafficking protein particle complex subunit 1 (sprot)

A trafficking protein particle complex subunit 1 that is encoded in the genome of human.


TRPV2_HUMAN Transient receptor potential cation channel subfamily V member 2 (sprot)

A transient receptor potential cation channel TRPV2 that is encoded in the genome of human.


MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta (sprot)

A serine/threonine-protein kinase MRCK beta that is encoded in the genome of human.


NOX1_HUMAN NADPH oxidase 1 (sprot)

An NADPH oxidase 1 that is encoded in the genome of human.


cellular stress response to acidic pH

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.


RBM8A_HUMAN RNA-binding protein 8A (sprot)

An RNA-binding protein 8A that is encoded in the genome of human.


DJC15_HUMAN DnaJ homolog subfamily C member 15 (sprot)

A DnaJ homolog subfamily C member 15 that is encoded in the genome of human.


UBP16_HUMAN Ubiquitin carboxyl-terminal hydrolase 16 (sprot)

A ubiquitin carboxyl-terminal hydrolase 16 that is encoded in the genome of human.


positive regulation of ribosome biogenesis

Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.


TSSC4_HUMAN U5 small nuclear ribonucleoprotein TSSC4 (sprot)

A protein TSSC4 that is encoded in the genome of human.


INSI2_HUMAN Insulin-induced gene 2 protein (sprot)

An insulin-induced gene 2 protein that is encoded in the genome of human.


TNR18_HUMAN Tumor necrosis factor receptor superfamily member 18 (sprot)

A tumor necrosis factor receptor superfamily member 18 that is encoded in the genome of human.


MPC1_HUMAN Mitochondrial pyruvate carrier 1 (sprot)

A brain protein 44-like protein that is encoded in the genome of human.


IR3IP_HUMAN Immediate early response 3-interacting protein 1 (sprot)

An immediate early response 3-interacting protein 1 that is encoded in the genome of human.


ZN706_HUMAN Zinc finger protein 706 (sprot)

A zinc finger protein 706 that is encoded in the genome of human.


MAGD1_HUMAN Melanoma-associated antigen D1 (sprot)

A melanoma-associated antigen D1 that is encoded in the genome of human.


KLF2_HUMAN Krueppel-like factor 2 (sprot)

A krueppel-like factor 2 that is encoded in the genome of human.


WIF1_HUMAN Wnt inhibitory factor 1 (sprot)

A Wnt inhibitory factor 1 that is encoded in the genome of human.


SNX14_HUMAN Sorting nexin-14 (sprot)

A sorting nexin-14 that is encoded in the genome of human.


SNX13_HUMAN Sorting nexin-13 (sprot)

A sorting nexin-13 that is encoded in the genome of human.


SNX11_HUMAN Sorting nexin-11 (sprot)

A sorting nexin-11 that is encoded in the genome of human.


SNX10_HUMAN Sorting nexin-10 (sprot)

A sorting nexin-10 that is encoded in the genome of human.


extrinsic component of endosome membrane

The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.


SNX9_HUMAN Sorting nexin-9 (sprot)

A sorting nexin-9 that is encoded in the genome of human.


SNX8_HUMAN Sorting nexin-8 (sprot)

A sorting nexin-8 that is encoded in the genome of human.


SNX5_HUMAN Sorting nexin-5 (sprot)

A sorting nexin-5 that is encoded in the genome of human.


macropinocytic cup

A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.


NR2E3_HUMAN Photoreceptor-specific nuclear receptor (sprot)

A photoreceptor-specific nuclear receptor that is encoded in the genome of human.


NPFF2_HUMAN Neuropeptide FF receptor 2 (sprot)

A neuropeptide FF receptor 2 that is encoded in the genome of human.


opioid receptor binding

Binding to an opioid receptor.


LIPG_HUMAN Endothelial lipase (sprot)

An endothelial lipase that is encoded in the genome of human.


FLVC1_HUMAN Heme transporter FLVCR1 (sprot)

A feline leukemia virus subgroup C receptor-related protein 1 that is encoded in the genome of human.


heme export

The directed movement of heme out of a cell or organelle.


NUBP2_HUMAN Cytosolic Fe-S cluster assembly factor NUBP2 (sprot)

A cytosolic Fe-S cluster assembly factor NUBP2 that is encoded in the genome of human.


GPR45_HUMAN Probable G-protein coupled receptor 45 (sprot)

A probable G-protein coupled receptor 45 that is encoded in the genome of human.


PD2R2_HUMAN Prostaglandin D2 receptor 2 (sprot)

A prostaglandin D2 receptor DP2 that is encoded in the genome of human.


PEX16_HUMAN Peroxisomal membrane protein PEX16 (sprot)

A peroxisomal membrane protein PEX16 that is encoded in the genome of human.


ER-dependent peroxisome organization

A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.


ER-dependent peroxisome localization

A process in which a protein is transported to, or maintained at, a location in a peroxisome via the endoplasmic reticulum.


ST14_HUMAN Suppressor of tumorigenicity 14 protein (sprot)

A suppressor of tumorigenicity 14 protein that is encoded in the genome of human.


LYVE1_HUMAN Lymphatic vessel endothelial hyaluronic acid receptor 1 (sprot)

A lymphatic vessel endothelial hyaluronic acid receptor 1 that is encoded in the genome of human.


SCNAA_HUMAN Sodium channel protein type 10 subunit alpha (sprot)

A sodium channel protein type 10 subunit alpha that is encoded in the genome of human.


BACE2_HUMAN Beta-secretase 2 (sprot)

A beta-secretase 2 that is encoded in the genome of human.


HEBP2_HUMAN Heme-binding protein 2 (sprot)

A heme-binding protein 2 that is encoded in the genome of human.


B3GT1_HUMAN Beta-1,3-galactosyltransferase 1 (sprot)

A beta-1,3-galactosyltransferase 1 that is encoded in the genome of human.


HCFC2_HUMAN Host cell factor 2 (sprot)

A host cell factor 2 that is encoded in the genome of human.


immune response involved in response to exogenous dsRNA

Any immune response that is involved in response to exogenous dsRNA.


UBIA1_HUMAN UbiA prenyltransferase domain-containing protein 1 (sprot)

A UbiA prenyltransferase domain-containing protein 1 that is encoded in the genome of human.


menaquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.


vitamin K biosynthetic process

The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.


CSAD_HUMAN Cysteine sulfinic acid decarboxylase (sprot)

A cysteine sulfinic acid decarboxylase that is encoded in the genome of human.


L-cysteine catabolic process to hypotaurine

The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine.


L-cysteine catabolic process to taurine

The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.


ETV7_HUMAN Transcription factor ETV7 (sprot)

A transcription factor ETV7 that is encoded in the genome of human.


MOFA1_HUMAN MORF4 family-associated protein 1 (sprot)

A MORF4 family-associated protein 1 that is encoded in the genome of human.


PUS1_HUMAN Pseudouridylate synthase 1 homolog (sprot)

A eukaryotic tRNA pseudouridine synthase A that is encoded in the genome of human.


LRRF2_HUMAN Leucine-rich repeat flightless-interacting protein 2 (sprot)

A leucine-rich repeat flightless-interacting protein 2 that is encoded in the genome of human.


FHOD1_HUMAN FH1/FH2 domain-containing protein 1 (sprot)

An FH1/FH2 domain-containing protein 1 that is encoded in the genome of human.


ACL7B_HUMAN Actin-like protein 7B (sprot)

An actin-like protein 7B that is encoded in the genome of human.


ACL7A_HUMAN Actin-like protein 7A (sprot)

An actin-like protein 7A that is encoded in the genome of human.


IRAK3_HUMAN Interleukin-1 receptor-associated kinase 3 (sprot)

An interleukin-1 receptor-associated kinase 3 that is encoded in the genome of human.


positive regulation of macrophage tolerance induction

Any process that increases the frequency, rate, or extent of B cell tolerance induction.


regulation of protein-containing complex disassembly

Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.


SERC_HUMAN Phosphoserine aminotransferase (sprot)

A phosphoserine aminotransferase that is encoded in the genome of human.


Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.


NCOR2_HUMAN Nuclear receptor corepressor 2 (sprot)

A nuclear receptor corepressor 2 that is encoded in the genome of human.


ORNT1_HUMAN Mitochondrial ornithine transporter 1 (sprot)

A mitochondrial ornithine transporter 1 that is encoded in the genome of human.


RA54B_HUMAN DNA repair and recombination protein RAD54B (sprot)

A DNA repair and recombination protein RAD54B that is encoded in the genome of human.


MYH4_HUMAN Myosin-4 (sprot)

A myosin-4 that is encoded in the genome of human.


JAM1_HUMAN Junctional adhesion molecule A (sprot)

A junctional adhesion molecule A that is encoded in the genome of human.


GPC6_HUMAN Glypican-6 (sprot)

A glypican-6 that is encoded in the genome of human.


NPTN_HUMAN Neuroplastin (sprot)

A neuroplastin that is encoded in the genome of human.


regulation of receptor localization to synapse

Any process that modulates the frequency, rate or extent of receptor localization to synapse.


RFNG_HUMAN Beta-1,3-N-acetylglucosaminyltransferase radical fringe (sprot)

A beta-1,3-N-acetylglucosaminyltransferase radical fringe that is encoded in the genome of human.


CBPQ_HUMAN Carboxypeptidase Q (sprot)

A carboxypeptidase Q that is encoded in the genome of human.


SOX21_HUMAN Transcription factor SOX-21 (sprot)

A transcription factor SOX-21 that is encoded in the genome of human.


AGRG1_HUMAN Adhesion G-protein coupled receptor G1 (sprot)

An adhesion G-protein coupled receptor G1 that is encoded in the genome of human.


SPIN1_HUMAN Spindlin-1 (sprot)

A spindlin-1 that is encoded in the genome of human.


HS3S4_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 4 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 4 that is encoded in the genome of human.


HS3SB_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 3B1 that is encoded in the genome of human.


[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity

Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.


HS3SA_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 3A1 that is encoded in the genome of human.


KPTN_HUMAN KICSTOR complex protein kaptin (sprot)

A KICSTOR complex protein kaptin that is encoded in the genome of human.


S12A7_HUMAN Solute carrier family 12 member 7 (sprot)

A solute carrier family 12 member 7 that is encoded in the genome of human.


ALG6_HUMAN Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (sprot)

A dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase that is encoded in the genome of human.


ALG5_HUMAN Dolichyl-phosphate beta-glucosyltransferase (sprot)

A dolichyl-phosphate beta-glucosyltransferase that is encoded in the genome of human.


oligosaccharyl transferase activity

Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.


Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.


SNURF_HUMAN SNRPN upstream reading frame protein (sprot)

A SNRPN upstream reading frame protein that is encoded in the genome of human.


RT18B_HUMAN Small ribosomal subunit protein mS40 (sprot)

A 28S ribosomal protein S18b, mitochondrial that is encoded in the genome of human.


COPG1_HUMAN Coatomer subunit gamma-1 (sprot)

A coatomer subunit gamma-1 that is encoded in the genome of human.


AUP1_HUMAN Lipid droplet-regulating VLDL assembly factor AUP1 (sprot)

A lipid droplet-regulating VLDL assembly factor AUP1 that is encoded in the genome of human.


FKBP7_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP7 (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP7 that is encoded in the genome of human.


ARL5A_HUMAN ADP-ribosylation factor-like protein 5A (sprot)

An ADP-ribosylation factor-like protein 5A that is encoded in the genome of human.


KCMB2_HUMAN Calcium-activated potassium channel subunit beta-2 (sprot)

A calcium-activated potassium channel subunit beta-2 that is encoded in the genome of human.


GMEB1_HUMAN Glucocorticoid modulatory element-binding protein 1 (sprot)

A glucocorticoid modulatory element-binding protein 1 that is encoded in the genome of human.


Hsp27 protein binding

Binding to Hsp27 proteins, a lightweight heat shock protein.


S22A7_HUMAN Solute carrier family 22 member 7 (sprot)

A solute carrier family 22 member 7 that is encoded in the genome of human.


CLIC4_HUMAN Chloride intracellular channel protein 4 (sprot)

A chloride intracellular channel protein 4 that is encoded in the genome of human.


establishment or maintenance of apical/basal cell polarity

Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.


NFS1_HUMAN Cysteine desulfurase (sprot)

A cysteine desulfurase NFS1 that is encoded in the genome of human.


cysteine desulfurase activity

Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.


CCG2_HUMAN Voltage-dependent calcium channel gamma-2 subunit (sprot)

A voltage-dependent calcium channel gamma-2 subunit that is encoded in the genome of human.


eye blink reflex

The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.


positive regulation of protein localization to basolateral plasma membrane

Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.


POMT1_HUMAN Protein O-mannosyl-transferase 1 (sprot)

A protein O-mannosyl-transferase 1 that is encoded in the genome of human.


CP46A_HUMAN Cholesterol 24-hydroxylase (sprot)

A cytochrome P450 46A1 that is encoded in the genome of human.


cholesterol 24-hydroxylase activity

Catalysis of the reaction: cholesterol + H+ + NADPH + O2 = (24S)-24-hydroxycholesterol + H2O + NADP+.


CFA20_HUMAN Cilia- and flagella-associated protein 20 (sprot)

A cilia- and flagella-associated protein 20 that is encoded in the genome of human.


TACC3_HUMAN Transforming acidic coiled-coil-containing protein 3 (sprot)

A transforming acidic coiled-coil-containing protein 3 that is encoded in the genome of human.


SPCS1_HUMAN Signal peptidase complex subunit 1 (sprot)

A signal peptidase complex subunit 1 that is encoded in the genome of human.


EID1_HUMAN EP300-interacting inhibitor of differentiation 1 (sprot)

An EP300-interacting inhibitor of differentiation 1 that is encoded in the genome of human.


SAR1B_HUMAN GTP-binding protein SAR1b (sprot)

A GTP-binding protein SAR1b that is encoded in the genome of human.


AP4B1_HUMAN AP-4 complex subunit beta-1 (sprot)

An AP-4 complex subunit beta-1 that is encoded in the genome of human.


protein localization to somatodendritic compartment

A process in which a protein is transported to or maintained in a location within the somatodendritic compartment.


cytoplasmic side of trans-Golgi network transport vesicle membrane

The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm.


EMIL1_HUMAN EMILIN-1 (sprot)

An EMILIN-1 that is encoded in the genome of human.


PTC2_HUMAN Protein patched homolog 2 (sprot)

A protein patched homolog 2 that is encoded in the genome of human.


MTCH2_HUMAN Mitochondrial carrier homolog 2 (sprot)

A mitochondrial carrier homolog 2 that is encoded in the genome of human.


SELK_HUMAN Selenoprotein K (sprot)

A selenoprotein K that is encoded in the genome of human.


BIG2_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (sprot)

A brefeldin A-inhibited guanine nucleotide-exchange protein 2 that is encoded in the genome of human.


endomembrane system organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.


BIG1_HUMAN Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (sprot)

A brefeldin A-inhibited guanine nucleotide-exchange protein 1 that is encoded in the genome of human.


MD1L1_HUMAN Mitotic spindle assembly checkpoint protein MAD1 (sprot)

A mitotic spindle assembly checkpoint protein MAD1 that is encoded in the genome of human.


MAD1 complex

A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C).


STK24_HUMAN Serine/threonine-protein kinase 24 (sprot)

A serine/threonine-protein kinase 24 that is encoded in the genome of human.


5MP1_HUMAN eIF5-mimic protein 1 (sprot)

An eIF5-mimic protein 1 that is encoded in the genome of human.


SIR4_HUMAN NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (sprot)

An NAD-dependent protein lipoamidase sirtuin-4, mitochondrial that is encoded in the genome of human.


lipoamidase activity

Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein.


NAD-dependent protein lipoamidase activity

Catalysis of the reaction: (R)-N6-lipoyl-L-lysyl-[protein] + H2O + NAD+ = 2''-O-lipoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


NAD-dependent protein biotinidase activity

Catalysis of the reaction: H2O + N6-biotinyl-L-lysyl-[protein] + NAD+ = 2''-O-biotinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


regulation of glutamine family amino acid metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.


regulation of pyruvate dehydrogenase activity

Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity.


PARP3_HUMAN Protein mono-ADP-ribosyltransferase PARP3 (sprot)

A protein mono-ADP-ribosyltransferase PARP3 that is encoded in the genome of human.


negative regulation of isotype switching

Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.


negative regulation of telomerase RNA reverse transcriptase activity

Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.


IRAG1_HUMAN Inositol 1,4,5-triphosphate receptor associated 1 (sprot)

An inositol 1,4,5-triphosphate receptor associated 1 that is encoded in the genome of human.


CDY2_HUMAN Testis-specific chromodomain protein Y 2 (sprot)

A testis-specific chromodomain protein Y 2 that is encoded in the genome of human.


CDY1_HUMAN Testis-specific chromodomain protein Y 1 (sprot)

A testis-specific chromodomain protein Y 1 that is encoded in the genome of human.


WNT6_HUMAN Protein Wnt-6 (sprot)

A protein Wnt-6 that is encoded in the genome of human.


axis specification

The establishment, maintenance and elaboration of a pattern along a line or around a point.


TM14A_HUMAN Transmembrane protein 14A (sprot)

A transmembrane protein 14A that is encoded in the genome of human.


RM42_HUMAN Large ribosomal subunit protein mL42 (sprot)

A 28S ribosomal protein L42, mitochondrial that is encoded in the genome of human.


COMDA_HUMAN COMM domain-containing protein 10 (sprot)

A COMM domain-containing protein 10 that is encoded in the genome of human.


DC1L1_HUMAN Cytoplasmic dynein 1 light intermediate chain 1 (sprot)

A cytoplasmic dynein 1 light intermediate chain 1 that is encoded in the genome of human.


CHCH2_HUMAN Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 (sprot)

A coiled-coil-helix-coiled-coil-helix domain-containing protein 2 that is encoded in the genome of human.


ATP23_HUMAN Mitochondrial inner membrane protease ATP23 homolog (sprot)

A mitochondrial inner membrane protease ATP23 that is encoded in the genome of human.


SNCAP_HUMAN Synphilin-1 (sprot)

A synphilin-1 that is encoded in the genome of human.


KCNE3_HUMAN Potassium voltage-gated channel subfamily E member 3 (sprot)

A potassium voltage-gated channel subfamily E member 3 that is encoded in the genome of human.


negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential

Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.


CXA3_HUMAN Gap junction alpha-3 protein (sprot)

A gap junction alpha-3 protein that is encoded in the genome of human.


EPN1_HUMAN Epsin-1 (sprot)

An epsin-1 that is encoded in the genome of human.


UBP3_HUMAN Ubiquitin carboxyl-terminal hydrolase 3 (sprot)

A ubiquitin carboxyl-terminal hydrolase 3 that is encoded in the genome of human.


WSB1_HUMAN WD repeat and SOCS box-containing protein 1 (sprot)

A WD repeat and SOCS box-containing protein 1 that is encoded in the genome of human.


protein aggregate center assembly

The reversible aggregation of misfolded proteins and chaperones, formed to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding.


PXMP4_HUMAN Peroxisomal membrane protein 4 (sprot)

A peroxisomal membrane protein 4 that is encoded in the genome of human.


TX264_HUMAN Testis-expressed protein 264 (sprot)

A testis-expressed protein 264 that is encoded in the genome of human.


CABIN_HUMAN Calcineurin-binding protein cabin-1 (sprot)

A calcineurin-binding protein cabin-1 that is encoded in the genome of human.


SMA5O_HUMAN SMAD5 antisense gene protein 1 (sprot)

A SMAD5 antisense gene protein 1 that is encoded in the genome of human.


KCNE2_HUMAN Potassium voltage-gated channel subfamily E member 2 (sprot)

A potassium voltage-gated channel subfamily E member 2 that is encoded in the genome of human.


STYL1_HUMAN Serine/threonine/tyrosine-interacting-like protein 1 (sprot)

A serine/threonine/tyrosine-interacting-like protein 1 that is encoded in the genome of human.


TAF6L_HUMAN TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (sprot)

A TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L that is encoded in the genome of human.


CEPT1_HUMAN Choline/ethanolaminephosphotransferase 1 (sprot)

A choline/ethanolaminephosphotransferase 1 that is encoded in the genome of human.


1-alkenyl-2-acylglycerol choline phosphotransferase activity

Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.


DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (sprot)

A DNA (cytosine-5)-methyltransferase 3A that is encoded in the genome of human.


OAS3_HUMAN 2'-5'-oligoadenylate synthase 3 (sprot)

A 2'-5'-oligoadenylate synthase 3 that is encoded in the genome of human.


negative regulation of chemokine (C-X-C motif) ligand 9 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


KAD5_HUMAN Adenylate kinase isoenzyme 5 (sprot)

An adenylate kinase isoenzyme 5 that is encoded in the genome of human.


dADP biosynthetic process

The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).


NEMO_HUMAN NF-kappa-B essential modulator (sprot)

An NF-kappa-B essential modulator that is encoded in the genome of human.


SO1B1_HUMAN Solute carrier organic anion transporter family member 1B1 (sprot)

A solute carrier organic anion transporter family member 1B1 that is encoded in the genome of human.


TLL2_HUMAN Tolloid-like protein 2 (sprot)

A tolloid-like protein 2 that is encoded in the genome of human.


TEST_HUMAN Testisin (sprot)

A testisin that is encoded in the genome of human.


IF2B2_HUMAN Insulin-like growth factor 2 mRNA-binding protein 2 (sprot)

An insulin-like growth factor 2 mRNA-binding protein 2 that is encoded in the genome of human.


translation regulator activity, nucleic acid binding

Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.


cold-induced thermogenesis

The process by which heat is generated by increasing metabolism in response to cold ambient temperatures in order to maintain a stable core body temperature.


KC1G3_HUMAN Casein kinase I isoform gamma-3 (sprot)

A casein kinase I isoform gamma-3 that is encoded in the genome of human.


ZNT1_HUMAN Proton-coupled zinc antiporter SLC30A1 (sprot)

A proton-coupled zinc antiporter SLC30A1 that is encoded in the genome of human.


negative regulation of zinc ion transmembrane import

Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.


detoxification of cadmium ion

Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.


S4A7_HUMAN Sodium bicarbonate cotransporter 3 (sprot)

A sodium bicarbonate cotransporter 3 that is encoded in the genome of human.


NDUB9_HUMAN NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (sprot)

An NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 that is encoded in the genome of human.


COX11_HUMAN Cytochrome c oxidase assembly protein COX11, mitochondrial (sprot)

A cytochrome c oxidase assembly protein COX11, mitochondrial that is encoded in the genome of human.


CLCA3_HUMAN Calcium-activated chloride channel regulator family member 3 (sprot)

A calcium-activated chloride channel regulator family member 3 that is encoded in the genome of human.


SQOR_HUMAN Sulfide:quinone oxidoreductase, mitochondrial (sprot)

A sulfide:quinone oxidoreductase, mitochondrial that is encoded in the genome of human.


Catalysis of the reaction: H2S (hydrogen sulfide) + a quinone = S0 (sulfane sulfur) + a hydroquinone.


glutathione-dependent sulfide quinone oxidoreductase activity

Catalysis of the reaction: a quinone + glutathione + H(+) + hydrogen sulfide <=> a quinol + S-sulfanylglutathione.


LAMC3_HUMAN Laminin subunit gamma-3 (sprot)

A laminin subunit gamma-3 that is encoded in the genome of human.


ROBO1_HUMAN Roundabout homolog 1 (sprot)

A roundabout homolog 1 that is encoded in the genome of human.


CAD10_HUMAN Cadherin-10 (sprot)

A cadherin-10 that is encoded in the genome of human.


USH1C_HUMAN Harmonin (sprot)

A harmonin that is encoded in the genome of human.


SESN1_HUMAN Sestrin-1 (sprot)

A sestrin-1 that is encoded in the genome of human.


CAN6_HUMAN Calpain-6 (sprot)

A calpain-6 that is encoded in the genome of human.


STON1_HUMAN Stonin-1 (sprot)

A stonin-1 that is encoded in the genome of human.


ZFP37_HUMAN Zinc finger protein 37 homolog (sprot)

A zinc finger protein 37 that is encoded in the genome of human.


AP1M2_HUMAN AP-1 complex subunit mu-2 (sprot)

An AP-1 complex subunit mu-2 that is encoded in the genome of human.