antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent

The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.


BTNL2_HUMAN Butyrophilin-like protein 2 (sprot)

A butyrophilin-like protein 2 that is encoded in the genome of human.


MBD1_HUMAN Methyl-CpG-binding domain protein 1 (sprot)

A methyl-CpG-binding domain protein 1 that is encoded in the genome of human.


SIX4_HUMAN Homeobox protein SIX4 (sprot)

A homeobox protein SIX4 that is encoded in the genome of human.


CNOT7_HUMAN CCR4-NOT transcription complex subunit 7 (sprot)

A CCR4-NOT transcription complex subunit 7 that is encoded in the genome of human.


SPB13_HUMAN Serpin B13 (sprot)

A serpin B13 that is encoded in the genome of human.


negative regulation of keratinocyte apoptotic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.


VAX2_HUMAN Ventral anterior homeobox 2 (sprot)

A ventral anterior homeobox 2 that is encoded in the genome of human.


PLXA1_HUMAN Plexin-A1 (sprot)

A plexin-A1 that is encoded in the genome of human.


KCNG1_HUMAN Potassium voltage-gated channel subfamily G member 1 (sprot)

A voltage-gated potassium channel KCNG1 that is encoded in the genome of human.


RWD2A_HUMAN RWD domain-containing protein 2A (sprot)

An RWD domain-containing protein 2A that is encoded in the genome of human.


TSYL4_HUMAN Testis-specific Y-encoded-like protein 4 (sprot)

A testis-specific Y-encoded-like protein 4 that is encoded in the genome of human.


GGT7_HUMAN Glutathione hydrolase 7 (sprot)

A glutathione hydrolase 7 that is encoded in the genome of human.


SIA7B_HUMAN Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (sprot)

An alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 that is encoded in the genome of human.


RABX5_HUMAN Rab5 GDP/GTP exchange factor (sprot)

A Rab5 GDP/GTP exchange factor that is encoded in the genome of human.


dendritic transport

The directed movement of organelles or molecules along microtubules in dendrites.


negative regulation of Kit signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.


GP160_HUMAN Probable G-protein coupled receptor 160 (sprot)

A probable G-protein coupled receptor 160 that is encoded in the genome of human.


MAGL2_HUMAN MAGE-like protein 2 (sprot)

A MAGE-like protein 2 that is encoded in the genome of human.


MSRA_HUMAN Mitochondrial peptide methionine sulfoxide reductase (sprot)

A peptide methionine sulfoxide reductase that is encoded in the genome of human.


NAGK_HUMAN N-acetyl-D-glucosamine kinase (sprot)

An N-acetyl-D-glucosamine kinase that is encoded in the genome of human.


N-acetylglucosamine kinase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H+.


muramyl dipeptide kinase activity

Catalysis of the reaction: ATP + muramyl dipeptide = ADP + H(+) + 6-O-phospho-muramyl dipeptide.


N-acetylmannosamine metabolic process

The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.


CLC4K_HUMAN C-type lectin domain family 4 member K (sprot)

A C-type lectin domain family 4 member K that is encoded in the genome of human.


ANX10_HUMAN Annexin A10 (sprot)

An annexin A10 that is encoded in the genome of human.


ZMYM5_HUMAN Zinc finger MYM-type protein 5 (sprot)

A zinc finger MYM-type protein 5 that is encoded in the genome of human.


HACL1_HUMAN 2-hydroxyacyl-CoA lyase 1 (sprot)

A 2-hydroxyacyl-CoA lyase 1 that is encoded in the genome of human.


carbon-carbon lyase activity

Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.


2-hydroxyacyl-CoA lyase activity

Catalysis of the reaction: a 2-hydroxy fatty acyl-CoA = a fatty aldehyde + formyl-CoA. The reaction acts on 2-hydroxy-3-methyl-branched fatty acyl-CoA and 2-hydroxy-long-chain fatty acyl-CoA.


2-hydroxyphytanoyl-CoA lyase activity

Catalysis of the reaction: 2-hydroxyphytanoyl-CoA = 2,6,10,14-tetramethylpentadecanal + formyl-CoA.


KCNE5_HUMAN Potassium voltage-gated channel subfamily E regulatory beta subunit 5 (sprot)

A potassium voltage-gated channel subfamily E regulatory beta subunit 5 that is encoded in the genome of human.


KCNG2_HUMAN Potassium voltage-gated channel subfamily G member 2 (sprot)

A voltage-gated potassium channel KCNG2 that is encoded in the genome of human.


STAG3_HUMAN Cohesin subunit SA-3 (sprot)

A cohesin subunit SA-3 that is encoded in the genome of human.


CAD22_HUMAN Cadherin-22 (sprot)

A cadherin-22 that is encoded in the genome of human.


CRLS1_HUMAN Cardiolipin synthase (CMP-forming) (sprot)

A CMP-forming cardiolipin synthase that is encoded in the genome of human.


cardiolipin synthase (CMP-forming)

Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.


response to phosphatidylethanolamine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.


MCM8_HUMAN DNA helicase MCM8 (sprot)

A DNA helicase MCM8 that is encoded in the genome of human.


TRM6_HUMAN tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (sprot)

A tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6 that is encoded in the genome of human.


ENPP5_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (sprot)

An ectonucleotide pyrophosphatase/phosphodiesterase family member 5 that is encoded in the genome of human.


HOOK1_HUMAN Protein Hook homolog 1 (sprot)

A protein Hook homolog 1 that is encoded in the genome of human.


SH3L2_HUMAN SH3 domain-binding glutamic acid-rich-like protein 2 (sprot)

An SH3 domain-binding glutamic acid-rich-like protein 2 that is encoded in the genome of human.


RIMS3_HUMAN Regulating synaptic membrane exocytosis protein 3 (sprot)

A regulating synaptic membrane exocytosis protein 3 that is encoded in the genome of human.


NGAP_HUMAN Ras GTPase-activating protein nGAP (sprot)

A Ras GTPase-activating protein nGAP that is encoded in the genome of human.


regulation of protein activation cascade

Any process that modulates the frequency, rate or extent of protein activation cascade.


MSPD1_HUMAN Motile sperm domain-containing protein 1 (sprot)

A motile sperm domain-containing protein 1 that is encoded in the genome of human.


METRN_HUMAN Meteorin (sprot)

A meteorin that is encoded in the genome of human.


RUSD1_HUMAN RNA pseudouridylate synthase domain-containing protein 1 (sprot)

An RNA pseudouridylate synthase domain-containing protein 1 that is encoded in the genome of human.


GNPTG_HUMAN N-acetylglucosamine-1-phosphotransferase subunit gamma (sprot)

An N-acetylglucosamine-1-phosphotransferase subunit gamma that is encoded in the genome of human.


biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.


TSR3_HUMAN 18S rRNA aminocarboxypropyltransferase (sprot)

An 18S rRNA aminocarboxypropyltransferase that is encoded in the genome of human.


18S rRNA aminocarboxypropyltransferase activity

Catalysis of the reaction: N1-methylpseudouridine in 18S rRNA + S-adenosyl-L-methionine = H+ + N1-methyl-N3-[(3S)-3-amino-3-carboxypropyl]pseudouridine in 18S rRNA + S-methyl-5'-thioadenosine.


ZF69B_HUMAN Zinc finger protein 69 homolog B (sprot)

A zinc finger protein 69 homolog B that is encoded in the genome of human.


ERRFI_HUMAN ERBB receptor feedback inhibitor 1 (sprot)

An ERBB receptor feedback inhibitor 1 that is encoded in the genome of human.


response to 1-oleoyl-sn-glycerol 3-phosphate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.


HAOX1_HUMAN 2-Hydroxyacid oxidase 1 (sprot)

A 2-hydroxyacid oxidase 1 that is encoded in the genome of human.


glyoxylate oxidase activity

Catalysis of the reaction: glyoxylate + H2O + O2 = H2O2 + H+ + oxalate.


glycolate catabolic process

The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).


ZN391_HUMAN Zinc finger protein 391 (sprot)

A zinc finger protein 391 that is encoded in the genome of human.


KLH21_HUMAN Kelch-like protein 21 (sprot)

A kelch-like protein 21 that is encoded in the genome of human.


chromosome passenger complex localization to spindle midzone

A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.


LAMP5_HUMAN Lysosome-associated membrane glycoprotein 5 (sprot)

A lysosome-associated membrane glycoprotein 5 that is encoded in the genome of human.


SALL4_HUMAN Sal-like protein 4 (sprot)

A Sal-like protein 4 that is encoded in the genome of human.


S2513_HUMAN Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (sprot)

An electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial that is encoded in the genome of human.


TBE_HUMAN Tubulin epsilon chain (sprot)

A tubulin epsilon chain that is encoded in the genome of human.


TBD_HUMAN Tubulin delta chain (sprot)

A tubulin delta chain that is encoded in the genome of human.


TSKS_HUMAN Testis-specific serine kinase substrate (sprot)

A testis-specific serine kinase substrate that is encoded in the genome of human.


FBXL7_HUMAN F-box/LRR-repeat protein 7 (sprot)

An F-box/LRR-repeat protein 7 that is encoded in the genome of human.


LEF1_HUMAN Lymphoid enhancer-binding factor 1 (sprot)

A lymphoid enhancer-binding factor 1 that is encoded in the genome of human.


ZN112_HUMAN Zinc finger protein 112 (sprot)

A zinc finger protein 112 that is encoded in the genome of human.


FOXD3_HUMAN Forkhead box protein D3 (sprot)

A forkhead box protein D3 that is encoded in the genome of human.


DBNL_HUMAN Drebrin-like protein (sprot)

A drebrin-like protein that is encoded in the genome of human.


TRIM1_HUMAN Probable E3 ubiquitin-protein ligase MID2 (sprot)

A midline-2 that is encoded in the genome of human.


PURG_HUMAN Purine-rich element-binding protein gamma (sprot)

A purine-rich element-binding protein gamma that is encoded in the genome of human.


DDX41_HUMAN Probable ATP-dependent RNA helicase DDX41 (sprot)

A probable ATP-dependent RNA helicase DDX41 that is encoded in the genome of human.


DCTN4_HUMAN Dynactin subunit 4 (sprot)

A dynactin subunit 4 that is encoded in the genome of human.


TINAG_HUMAN Tubulointerstitial nephritis antigen (sprot)

A tubulointerstitial nephritis antigen that is encoded in the genome of human.


DNM3L_HUMAN DNA (cytosine-5)-methyltransferase 3-like (sprot)

A DNA (cytosine-5)-methyltransferase 3-like that is encoded in the genome of human.


negative regulation of DNA methylation

Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.


ZN229_HUMAN Zinc finger protein 229 (sprot)

A zinc finger protein 229 that is encoded in the genome of human.


ZN180_HUMAN Zinc finger protein 180 (sprot)

A zinc finger protein 180 that is encoded in the genome of human.


SRTD3_HUMAN SERTA domain-containing protein 3 (sprot)

A SERTA domain-containing protein 3 that is encoded in the genome of human.


OSGI1_HUMAN Oxidative stress-induced growth inhibitor 1 (sprot)

An oxidative stress-induced growth inhibitor 1 that is encoded in the genome of human.


CDC23_HUMAN Cell division cycle protein 23 homolog (sprot)

A cell division cycle protein 23 that is encoded in the genome of human.


APC7_HUMAN Anaphase-promoting complex subunit 7 (sprot)

An anaphase-promoting complex subunit 7 that is encoded in the genome of human.


APC5_HUMAN Anaphase-promoting complex subunit 5 (sprot)

An anaphase-promoting complex subunit 5 that is encoded in the genome of human.


APC4_HUMAN Anaphase-promoting complex subunit 4 (sprot)

An anaphase-promoting complex subunit 4 that is encoded in the genome of human.


ANC2_HUMAN Anaphase-promoting complex subunit 2 (sprot)

An anaphase-promoting complex subunit 2 that is encoded in the genome of human.


HSPB8_HUMAN Heat shock protein beta-8 (sprot)

A heat shock protein beta-8 that is encoded in the genome of human.


GGA2_HUMAN ADP-ribosylation factor-binding protein GGA2 (sprot)

An ADP-ribosylation factor-binding protein GGA2 that is encoded in the genome of human.


GGA1_HUMAN ADP-ribosylation factor-binding protein GGA1 (sprot)

An ADP-ribosylation factor-binding protein GGA1 that is encoded in the genome of human.


STML2_HUMAN Stomatin-like protein 2, mitochondrial (sprot)

A stomatin-like protein 2 that is encoded in the genome of human.


lipid localization

Any process in which a lipid is transported to, or maintained in, a specific location.


CC018_HUMAN Uncharacterized protein C3orf18 (sprot)

An uncharacterized protein C3orf18 that is encoded in the genome of human.


GDF2_HUMAN Growth/differentiation factor 2 (sprot)

A growth/differentiation factor 2 that is encoded in the genome of human.


GBG8_HUMAN Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 (sprot)

A guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 that is encoded in the genome of human.


cellular response to pheromone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.


ZN225_HUMAN Zinc finger protein 225 (sprot)

A zinc finger protein 225 that is encoded in the genome of human.


ZN223_HUMAN Zinc finger protein 223 (sprot)

A zinc finger protein 223 that is encoded in the genome of human.


ZN222_HUMAN Zinc finger protein 222 (sprot)

A zinc finger protein 222 that is encoded in the genome of human.


ZN221_HUMAN Zinc finger protein 221 (sprot)

A zinc finger protein 221 that is encoded in the genome of human.


KCND3_HUMAN Potassium voltage-gated channel subfamily D member 3 (sprot)

A voltage-gated potassium channel KCND3 that is encoded in the genome of human.


FBX2_HUMAN F-box only protein 2 (sprot)

An F-box only protein 2 that is encoded in the genome of human.


NAGPA_HUMAN N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (sprot)

An N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase that is encoded in the genome of human.


Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.


TM59L_HUMAN Transmembrane protein 59-like (sprot)

A transmembrane protein 59-like that is encoded in the genome of human.


KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 (sprot)

A ribosomal protein S6 kinase alpha-6 that is encoded in the genome of human.


negative regulation of embryonic development

Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.


ZN580_HUMAN Zinc finger protein 580 (sprot)

A zinc finger protein 580 that is encoded in the genome of human.


NOCT_HUMAN Nocturnin (sprot)

A nocturnin that is encoded in the genome of human.


NADP phosphatase activity

Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.


NADPH phosphatase activity

Catalysis of the reaction: NADPH + H2O = NADH + hydrogenphosphate.


VPS28_HUMAN Vacuolar protein sorting-associated protein 28 homolog (sprot)

A vacuolar protein sorting-associated protein 28 that is encoded in the genome of human.


LSM7_HUMAN U6 snRNA-associated Sm-like protein LSm7 (sprot)

A U6 snRNA-associated Sm-like protein LSm7 that is encoded in the genome of human.


ING1_HUMAN Inhibitor of growth protein 1 (sprot)

An inhibitor of growth protein 1 that is encoded in the genome of human.


ZPI_HUMAN Protein Z-dependent protease inhibitor (sprot)

A protein Z-dependent protease inhibitor that is encoded in the genome of human.


CCNL1_HUMAN Cyclin-L1 (sprot)

A cyclin-L1 that is encoded in the genome of human.


DBR1_HUMAN Lariat debranching enzyme (sprot)

A lariat debranching enzyme that is encoded in the genome of human.


RNA lariat debranching enzyme activity

Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.


TASOR_HUMAN Protein TASOR (sprot)

A protein TASOR that is encoded in the genome of human.


FEM1B_HUMAN Protein fem-1 homolog B (sprot)

A protein fem-1 homolog B that is encoded in the genome of human.


JUPI1_HUMAN Jupiter microtubule associated homolog 1 (sprot)

A jupiter microtubule associated homolog 1 that is encoded in the genome of human.


UBP21_HUMAN Ubiquitin carboxyl-terminal hydrolase 21 (sprot)

A ubiquitin carboxyl-terminal hydrolase 21 that is encoded in the genome of human.


DKKL1_HUMAN Dickkopf-like protein 1 (sprot)

A dickkopf-like protein 1 that is encoded in the genome of human.


FBX10_HUMAN F-box only protein 10 (sprot)

An F-box only protein 10 that is encoded in the genome of human.


FBX9_HUMAN F-box only protein 9 (sprot)

An F-box only protein 9 that is encoded in the genome of human.


FBX3_HUMAN F-box only protein 3 (sprot)

An F-box only protein 3 that is encoded in the genome of human.


FBXL5_HUMAN F-box/LRR-repeat protein 5 (sprot)

An F-box/LRR-repeat protein 5 that is encoded in the genome of human.


FBXL4_HUMAN F-box/LRR-repeat protein 4 (sprot)

An F-box/LRR-repeat protein 4 that is encoded in the genome of human.


AKA11_HUMAN A-kinase anchor protein 11 (sprot)

An A-kinase anchor protein 11 that is encoded in the genome of human.


RCAN3_HUMAN Calcipressin-3 (sprot)

A calcipressin-3 that is encoded in the genome of human.


PTBP2_HUMAN Polypyrimidine tract-binding protein 2 (sprot)

A polypyrimidine tract-binding protein 2 that is encoded in the genome of human.


FBW1B_HUMAN F-box/WD repeat-containing protein 11 (sprot)

An F-box/WD repeat-containing protein 11 that is encoded in the genome of human.


DJC12_HUMAN DnaJ homolog subfamily C member 12 (sprot)

A DnaJ homolog subfamily C member 12 that is encoded in the genome of human.


AJAP1_HUMAN Adherens junction-associated protein 1 (sprot)

An adherens junction-associated protein 1 that is encoded in the genome of human.


regulation of polarized epithelial cell differentiation

Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation.


FBXL2_HUMAN F-box/LRR-repeat protein 2 (sprot)

An F-box/LRR-repeat protein 2 that is encoded in the genome of human.


GMEB2_HUMAN Glucocorticoid modulatory element-binding protein 2 (sprot)

A glucocorticoid modulatory element-binding protein 2 that is encoded in the genome of human.


MRT4_HUMAN mRNA turnover protein 4 homolog (sprot)

An mRNA turnover protein 4 that is encoded in the genome of human.


TNIK_HUMAN TRAF2 and NCK-interacting protein kinase (sprot)

A TRAF2 and NCK-interacting protein kinase that is encoded in the genome of human.


ADA30_HUMAN Disintegrin and metalloproteinase domain-containing protein 30 (sprot)

A disintegrin and metalloproteinase domain-containing protein 30 that is encoded in the genome of human.


ADA29_HUMAN Disintegrin and metalloproteinase domain-containing protein 29 (sprot)

A disintegrin and metalloproteinase domain-containing protein 29 that is encoded in the genome of human.


CPSF3_HUMAN Cleavage and polyadenylation specificity factor subunit 3 (sprot)

A cleavage and polyadenylation specificity factor subunit 3 that is encoded in the genome of human.


PITC1_HUMAN Cytoplasmic phosphatidylinositol transfer protein 1 (sprot)

A cytoplasmic phosphatidylinositol transfer protein 1 that is encoded in the genome of human.


DP13A_HUMAN DCC-interacting protein 13-alpha (sprot)

A DCC-interacting protein 13-alpha that is encoded in the genome of human.


negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.


S13A4_HUMAN Solute carrier family 13 member 4 (sprot)

A solute carrier family 13 member 4 that is encoded in the genome of human.


OCTC_HUMAN Peroxisomal carnitine O-octanoyltransferase (sprot)

A peroxisomal carnitine O-octanoyltransferase that is encoded in the genome of human.


BORG2_HUMAN Cdc42 effector protein 3 (sprot)

A Cdc42 effector protein 3 that is encoded in the genome of human.


cytoskeletal regulatory protein binding

Binding to a protein involved in modulating the reorganization of the cytoskeleton.


VPRE3_HUMAN Pre-B lymphocyte protein 3 (sprot)

A pre-B lymphocyte protein 3 that is encoded in the genome of human.


TLK1_HUMAN Serine/threonine-protein kinase tousled-like 1 (sprot)

A serine/threonine-protein kinase tousled-like 1 that is encoded in the genome of human.


PO2F3_HUMAN POU domain, class 2, transcription factor 3 (sprot)

A POU domain, class 2, transcription factor 3 that is encoded in the genome of human.


PILRB_HUMAN Paired immunoglobulin-like type 2 receptor beta (sprot)

A paired immunoglobulin-like type 2 receptor beta that is encoded in the genome of human.


PILRA_HUMAN Paired immunoglobulin-like type 2 receptor alpha (sprot)

A paired immunoglobulin-like type 2 receptor alpha that is encoded in the genome of human.


GPTC8_HUMAN G patch domain-containing protein 8 (sprot)

A G patch domain-containing protein 8 that is encoded in the genome of human.


CHIC2_HUMAN Cysteine-rich hydrophobic domain-containing protein 2 (sprot)

A cysteine-rich hydrophobic domain-containing protein 2 that is encoded in the genome of human.


ADA21_HUMAN Disintegrin and metalloproteinase domain-containing protein 21 (sprot)

A disintegrin and metalloproteinase domain-containing protein 21 that is encoded in the genome of human.


PARP4_HUMAN Protein mono-ADP-ribosyltransferase PARP4 (sprot)

A protein mono-ADP-ribosyltransferase PARP4 that is encoded in the genome of human.


NXT1_HUMAN NTF2-related export protein 1 (sprot)

An NTF2-related export protein 1 that is encoded in the genome of human.


NUDT5_HUMAN ADP-sugar pyrophosphatase (sprot)

An ADP-sugar pyrophosphatase that is encoded in the genome of human.


ribonucleoside diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.


RCOR1_HUMAN REST corepressor 1 (sprot)

A REST corepressor 1 that is encoded in the genome of human.


O52A1_HUMAN Olfactory receptor 52A1 (sprot)

An olfactory receptor 52A1 that is encoded in the genome of human.


C8AP2_HUMAN CASP8-associated protein 2 (sprot)

A CASP8-associated protein 2 that is encoded in the genome of human.


CXD2_HUMAN Gap junction delta-2 protein (sprot)

A gap junction delta-2 protein that is encoded in the genome of human.


PPCT_HUMAN Phosphatidylcholine transfer protein (sprot)

A phosphatidylcholine transfer protein that is encoded in the genome of human.


MA1B1_HUMAN Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (sprot)

An endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase that is encoded in the genome of human.


protein alpha-1,2-demannosylation

The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.


endoplasmic reticulum mannose trimming

Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC).


RALY_HUMAN RNA-binding protein Raly (sprot)

An RNA-binding protein Raly that is encoded in the genome of human.


MUC12_HUMAN Mucin-12 (sprot)

A mucin-12 that is encoded in the genome of human.


PRDM4_HUMAN PR domain zinc finger protein 4 (sprot)

A PR domain zinc finger protein 4 that is encoded in the genome of human.


MYO15_HUMAN Unconventional myosin-XV (sprot)

A myosin-XV that is encoded in the genome of human.


TF3C4_HUMAN General transcription factor 3C polypeptide 4 (sprot)

A general transcription factor 3C polypeptide 4 that is encoded in the genome of human.


ITBP2_HUMAN Integrin beta-1-binding protein 2 (sprot)

An integrin beta-1-binding protein 2 that is encoded in the genome of human.


ATS7_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 7 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 7 that is encoded in the genome of human.


ATS6_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 6 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 6 that is encoded in the genome of human.


UR2R_HUMAN Urotensin-2 receptor (sprot)

A urotensin-2 receptor that is encoded in the genome of human.


ADA28_HUMAN Disintegrin and metalloproteinase domain-containing protein 28 (sprot)

A disintegrin and metalloproteinase domain-containing protein 28 that is encoded in the genome of human.


KLK9_HUMAN Kallikrein-9 (sprot)

A kallikrein-9 that is encoded in the genome of human.


KLK12_HUMAN Kallikrein-12 (sprot)

A kallikrein-12 that is encoded in the genome of human.


KLK13_HUMAN Kallikrein-13 (sprot)

A kallikrein-13 that is encoded in the genome of human.


ERG28_HUMAN Ergosterol biosynthetic protein 28 homolog (sprot)

An ergosterol biosynthetic protein 28 homolog that is encoded in the genome of human.


TSN16_HUMAN Tetraspanin-16 (sprot)

A tetraspanin-16 that is encoded in the genome of human.


PACN3_HUMAN Protein kinase C and casein kinase substrate in neurons protein 3 (sprot)

A protein kinase C and casein kinase substrate in neurons protein 3 that is encoded in the genome of human.


IKZF2_HUMAN Zinc finger protein Helios (sprot)

A zinc finger protein Helios that is encoded in the genome of human.


FBX5_HUMAN F-box only protein 5 (sprot)

An F-box only protein 5 that is encoded in the genome of human.


negative regulation of DNA endoreduplication

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.


FBX4_HUMAN F-box only protein 4 (sprot)

An F-box only protein 4 that is encoded in the genome of human.


FXL21_HUMAN Putative F-box/LRR-repeat protein 21 (sprot)

A putative F-box/LRR-repeat protein 21 that is encoded in the genome of human.


FBXL3_HUMAN F-box/LRR-repeat protein 3 (sprot)

An F-box/LRR-repeat protein 3 that is encoded in the genome of human.


FBXW2_HUMAN F-box/WD repeat-containing protein 2 (sprot)

An F-box/WD repeat-containing protein 2 that is encoded in the genome of human.


IKZF3_HUMAN Zinc finger protein Aiolos (sprot)

A zinc finger protein Aiolos that is encoded in the genome of human.


ACSL6_HUMAN Long-chain-fatty-acid--CoA ligase 6 (sprot)

A long-chain-fatty-acid--CoA ligase 6 that is encoded in the genome of human.


TRHDE_HUMAN Thyrotropin-releasing hormone-degrading ectoenzyme (sprot)

A thyrotropin-releasing hormone-degrading ectoenzyme that is encoded in the genome of human.


ACAD8_HUMAN Isobutyryl-CoA dehydrogenase, mitochondrial (sprot)

An isobutyryl-CoA dehydrogenase, mitochondrial that is encoded in the genome of human.


ANGL2_HUMAN Angiopoietin-related protein 2 (sprot)

An angiopoietin-related protein 2 that is encoded in the genome of human.


HDAC9_HUMAN Histone deacetylase 9 (sprot)

A histone deacetylase 9 that is encoded in the genome of human.


histone H3K14 deacetylase activity

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.


histone H3K9 deacetylase activity

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.


histone H4K16 deacetylase activity

Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.


regulation of skeletal muscle fiber development

Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.


regulation of striated muscle cell differentiation

Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.


ACINU_HUMAN Apoptotic chromatin condensation inducer in the nucleus (sprot)

An apoptotic chromatin condensation inducer in the nucleus that is encoded in the genome of human.


AMFR_HUMAN E3 ubiquitin-protein ligase AMFR (sprot)

An E3 ubiquitin-protein ligase AMFR that is encoded in the genome of human.


AGO2_HUMAN Protein argonaute-2 (sprot)

A protein argonaute-2 that is encoded in the genome of human.


endoribonuclease activity, cleaving siRNA-paired mRNA

Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.


VAV3_HUMAN Guanine nucleotide exchange factor VAV3 (sprot)

A guanine nucleotide exchange factor VAV3 that is encoded in the genome of human.


ELF5_HUMAN ETS-related transcription factor Elf-5 (sprot)

An ETS-related transcription factor Elf-5 that is encoded in the genome of human.


MYH2_HUMAN Myosin-2 (sprot)

A myosin-2 that is encoded in the genome of human.


MYH13_HUMAN Myosin-13 (sprot)

A myosin-13 that is encoded in the genome of human.


ITA11_HUMAN Integrin alpha-11 (sprot)

An integrin alpha-11 that is encoded in the genome of human.


NUP50_HUMAN Nuclear pore complex protein Nup50 (sprot)

A nuclear pore complex protein Nup50 that is encoded in the genome of human.


PRND_HUMAN Prion-like protein doppel (sprot)

A prion-like protein doppel that is encoded in the genome of human.


ZHX1_HUMAN Zinc fingers and homeoboxes protein 1 (sprot)

A zinc fingers and homeoboxes protein 1 that is encoded in the genome of human.


CES1P_HUMAN Putative inactive carboxylesterase 4 (sprot)

A putative inactive carboxylesterase 4 that is encoded in the genome of human.


POMT2_HUMAN Protein O-mannosyl-transferase 2 (sprot)

A protein O-mannosyl-transferase 2 that is encoded in the genome of human.


CDV3_HUMAN Protein CDV3 homolog (sprot)

A protein CDV3 that is encoded in the genome of human.


CNO11_HUMAN CCR4-NOT transcription complex subunit 11 (sprot)

A CCR4-NOT transcription complex subunit 11 that is encoded in the genome of human.


TEN1_HUMAN Teneurin-1 (sprot)

A teneurin-1 that is encoded in the genome of human.


PCOC2_HUMAN Procollagen C-endopeptidase enhancer 2 (sprot)

A procollagen C-endopeptidase enhancer 2 that is encoded in the genome of human.


DSE_HUMAN Dermatan-sulfate epimerase (sprot)

A dermatan-sulfate epimerase that is encoded in the genome of human.


INT6_HUMAN Integrator complex subunit 6 (sprot)

An integrator complex subunit 6 that is encoded in the genome of human.


SARDH_HUMAN Sarcosine dehydrogenase, mitochondrial (sprot)

A sarcosine dehydrogenase, mitochondrial that is encoded in the genome of human.


BAG5_HUMAN BAG family molecular chaperone regulator 5 (sprot)

A BAG family molecular chaperone regulator 5 that is encoded in the genome of human.


regulation of inclusion body assembly

Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.


CFA45_HUMAN Cilia- and flagella-associated protein 45 (sprot)

A cilia- and flagella-associated protein 45 that is encoded in the genome of human.


TBX21_HUMAN T-box transcription factor TBX21 (sprot)

A T-box transcription factor TBX21 that is encoded in the genome of human.


AGO1_HUMAN Protein argonaute-1 (sprot)

A protein argonaute-1 that is encoded in the genome of human.


PLAT4_HUMAN Phospholipase A and acyltransferase 4 (sprot)

A phospholipase A and acyltransferase 4 that is encoded in the genome of human.


RAB21_HUMAN Ras-related protein Rab-21 (sprot)

A Ras-related protein Rab-21 that is encoded in the genome of human.


RB22A_HUMAN Ras-related protein Rab-22A (sprot)

A Ras-related protein Rab-22A that is encoded in the genome of human.


TPC2L_HUMAN Trafficking protein particle complex subunit 2-like protein (sprot)

A trafficking protein particle complex subunit 2-like protein that is encoded in the genome of human.


ZN236_HUMAN Zinc finger protein 236 (sprot)

A zinc finger protein 236 that is encoded in the genome of human.


ZN346_HUMAN Zinc finger protein 346 (sprot)

A zinc finger protein 346 that is encoded in the genome of human.


PNMA3_HUMAN Paraneoplastic antigen Ma3 (sprot)

A paraneoplastic antigen Ma3 that is encoded in the genome of human.


PNMA2_HUMAN Paraneoplastic antigen Ma2 (sprot)

A paraneoplastic antigen Ma2 that is encoded in the genome of human.


BL1S6_HUMAN Biogenesis of lysosome-related organelles complex 1 subunit 6 (sprot)

A biogenesis of lysosome-related organelles complex 1 subunit 6 that is encoded in the genome of human.


membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.


PSME2_HUMAN Proteasome activator complex subunit 2 (sprot)

A proteasome activator complex subunit 2 that is encoded in the genome of human.


TCFL5_HUMAN Transcription factor-like 5 protein (sprot)

A transcription factor-like 5 protein that is encoded in the genome of human.


HCN2_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 that is encoded in the genome of human.


TM11E_HUMAN Transmembrane protease serine 11E (sprot)

A transmembrane protease serine 11E that is encoded in the genome of human.


TAOK2_HUMAN Serine/threonine-protein kinase TAO2 (sprot)

A serine/threonine-protein kinase TAO2 that is encoded in the genome of human.


basal dendrite morphogenesis

The process in which the anatomical structures of a basal dendrite are generated and organized.


ZN215_HUMAN Zinc finger protein 215 (sprot)

A zinc finger protein 215 that is encoded in the genome of human.


ZN214_HUMAN Zinc finger protein 214 (sprot)

A zinc finger protein 214 that is encoded in the genome of human.


TRPC5_HUMAN Short transient receptor potential channel 5 (sprot)

A short transient receptor potential channel 5 that is encoded in the genome of human.


regulation of membrane hyperpolarization

Any process that modulates the frequency, rate or extent of membrane hyperpolarization.


MKLN1_HUMAN Muskelin (sprot)

A muskelin that is encoded in the genome of human.


MYT1L_HUMAN Myelin transcription factor 1-like protein (sprot)

A myelin transcription factor 1-like protein that is encoded in the genome of human.


DNPEP_HUMAN Aspartyl aminopeptidase (sprot)

An aspartyl aminopeptidase that is encoded in the genome of human.


NRX1A_HUMAN Neurexin-1 (sprot)

A neurexin-1-alpha that is encoded in the genome of human.


CADH9_HUMAN Cadherin-9 (sprot)

A cadherin-9 that is encoded in the genome of human.


CADH7_HUMAN Cadherin-7 (sprot)

A cadherin-7 that is encoded in the genome of human.


MUCEN_HUMAN Endomucin (sprot)

An endomucin that is encoded in the genome of human.


RAB23_HUMAN Ras-related protein Rab-23 (sprot)

A Ras-related protein Rab-23 that is encoded in the genome of human.


MCTS1_HUMAN Malignant T-cell-amplified sequence 1 (sprot)

A malignant T cell-amplified sequence 1 that is encoded in the genome of human.


ACSL5_HUMAN Long-chain-fatty-acid--CoA ligase 5 (sprot)

A long-chain-fatty-acid--CoA ligase 5 that is encoded in the genome of human.


PADI1_HUMAN Protein-arginine deiminase type-1 (sprot)

A protein-arginine deiminase type-1 that is encoded in the genome of human.


protein-arginine deiminase activity

Catalysis of the reaction: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4+, resulting in citrullination of the target protein. This reaction is calcium-dependent.


ZDHC8_HUMAN Palmitoyltransferase ZDHHC8 (sprot)

A palmitoyltransferase ZDHHC8 that is encoded in the genome of human.


OGDHL_HUMAN 2-oxoglutarate dehydrogenase-like, mitochondrial (sprot)

A 2-oxoglutarate dehydrogenase-like, mitochondrial that is encoded in the genome of human.


MTUS1_HUMAN Microtubule-associated tumor suppressor 1 (sprot)

A mitochondrial tumor suppressor 1 that is encoded in the genome of human.


BRPF3_HUMAN Bromodomain and PHD finger-containing protein 3 (sprot)

A bromodomain and PHD finger-containing protein 3 that is encoded in the genome of human.


ZN777_HUMAN Zinc finger protein 777 (sprot)

A zinc finger protein 777 that is encoded in the genome of human.


INTU_HUMAN Protein inturned (sprot)

A protein inturned that is encoded in the genome of human.


KCNH3_HUMAN Potassium voltage-gated channel subfamily H member 3 (sprot)

A voltage-gated potassium channel KCNH3 that is encoded in the genome of human.


ZN608_HUMAN Zinc finger protein 608 (sprot)

A zinc finger protein 608 that is encoded in the genome of human.


WWC3_HUMAN Protein WWC3 (sprot)

A protein WWC3 that is encoded in the genome of human.


DEN2A_HUMAN DENN domain-containing protein 2A (sprot)

A DENN domain-containing protein 2A that is encoded in the genome of human.


PALD_HUMAN Paladin (sprot)

A paladin that is encoded in the genome of human.


S39AA_HUMAN Zinc transporter ZIP10 (sprot)

A zinc transporter ZIP10 that is encoded in the genome of human.


INO80_HUMAN Chromatin-remodeling ATPase INO80 (sprot)

A chromatin-remodeling ATPase INO80 that is encoded in the genome of human.


CCPG1_HUMAN Cell cycle progression protein 1 (sprot)

A cell cycle progression protein 1 that is encoded in the genome of human.


KDIS_HUMAN Kinase D-interacting substrate of 220 kDa (sprot)

A kinase D-interacting substrate of 220 kDa that is encoded in the genome of human.


ASAP1_HUMAN Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (sprot)

An Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 that is encoded in the genome of human.


LRFN2_HUMAN Leucine-rich repeat and fibronectin type-III domain-containing protein 2 (sprot)

A leucine-rich repeat and fibronectin type-III domain-containing protein 2 that is encoded in the genome of human.


MRTFB_HUMAN Myocardin-related transcription factor B (sprot)

A myocardin-related transcription factor B that is encoded in the genome of human.


ATD2B_HUMAN ATPase family AAA domain-containing protein 2B (sprot)

An ATPase family AAA domain-containing protein 2B that is encoded in the genome of human.


RIMKB_HUMAN Beta-citrylglutamate synthase B (sprot)

A beta-citrylglutamate synthase B that is encoded in the genome of human.


citrate-L-glutamate ligase activity

Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.


HEG1_HUMAN Protein HEG homolog 1 (sprot)

A protein HEG homolog 1 that is encoded in the genome of human.


cardiac muscle tissue growth

The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.


KI26A_HUMAN Kinesin-like protein KIF26A (sprot)

A kinesin-like protein KIF26A that is encoded in the genome of human.


ODF2L_HUMAN Protein BCAP (sprot)

A protein BCAP that is encoded in the genome of human.


ZBT21_HUMAN Zinc finger and BTB domain-containing protein 21 (sprot)

A zinc finger and BTB domain-containing protein 21 that is encoded in the genome of human.


ZMIZ1_HUMAN Zinc finger MIZ domain-containing protein 1 (sprot)

A zinc finger MIZ domain-containing protein 1 that is encoded in the genome of human.


ANR50_HUMAN Ankyrin repeat domain-containing protein 50 (sprot)

An ankyrin repeat domain-containing protein 50 that is encoded in the genome of human.


NEB1_HUMAN Neurabin-1 (sprot)

A neurabin-1 that is encoded in the genome of human.


GRID1_HUMAN Glutamate receptor ionotropic, delta-1 (sprot)

A glutamate receptor ionotropic, delta-1 that is encoded in the genome of human.


AT7L1_HUMAN Ataxin-7-like protein 1 (sprot)

An ataxin-7-like protein 1 that is encoded in the genome of human.


MED23_HUMAN Mediator of RNA polymerase II transcription subunit 23 (sprot)

A mediator of RNA polymerase II transcription subunit 23 that is encoded in the genome of human.


VANG2_HUMAN Vang-like protein 2 (sprot)

A Vang-like protein 2 that is encoded in the genome of human.


cell migration involved in kidney development

The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.


RN150_HUMAN RING finger protein 150 (sprot)

A RING finger protein 150 that is encoded in the genome of human.


K1210_HUMAN Acrosomal protein KIAA1210 (sprot)

An acrosomal protein KIAA1210 that is encoded in the genome of human.


basal ectoplasmic specialization

Testis-specific junction between mature Sertoli cells involved in establishing the blood-testis barrier of the Sertoli cell.


PKHG1_HUMAN Pleckstrin homology domain-containing family G member 1 (sprot)

A pleckstrin homology domain-containing family G member 1 that is encoded in the genome of human.


PLXB3_HUMAN Plexin-B3 (sprot)

A plexin-B3 that is encoded in the genome of human.


PRR12_HUMAN Proline-rich protein 12 (sprot)

A proline-rich protein 12 that is encoded in the genome of human.


SHRM4_HUMAN Protein Shroom4 (sprot)

A protein Shroom4 that is encoded in the genome of human.


PKHH1_HUMAN Pleckstrin homology domain-containing family H member 1 (sprot)

A pleckstrin homology domain-containing family H member 1 that is encoded in the genome of human.


ZN490_HUMAN Zinc finger protein 490 (sprot)

A zinc finger protein 490 that is encoded in the genome of human.


YETS2_HUMAN YEATS domain-containing protein 2 (sprot)

A YEATS domain-containing protein 2 that is encoded in the genome of human.


CNOT6_HUMAN CCR4-NOT transcription complex subunit 6 (sprot)

A CCR4-NOT transcription complex subunit 6 that is encoded in the genome of human.


NDRG4_HUMAN Protein NDRG4 (sprot)

A protein NDRG4 that is encoded in the genome of human.


TBC24_HUMAN TBC1 domain family member 24 (sprot)

A TBC1 domain family member 24 that is encoded in the genome of human.


STRP2_HUMAN Striatin-interacting protein 2 (sprot)

A protein FAM40B that is encoded in the genome of human.


TPC1_HUMAN Two pore channel protein 1 (sprot)

A two pore channel protein 1 that is encoded in the genome of human.


ISY1_HUMAN Pre-mRNA-splicing factor ISY1 homolog (sprot)

A pre-mRNA-splicing factor ISY1 that is encoded in the genome of human.


PPM1H_HUMAN Protein phosphatase 1H (sprot)

A protein phosphatase 1H that is encoded in the genome of human.


PAI2B_HUMAN Polyadenylate-binding protein-interacting protein 2B (sprot)

A polyadenylate-binding protein-interacting protein 2B that is encoded in the genome of human.


TMCC3_HUMAN Transmembrane and coiled-coil domain protein 3 (sprot)

A transmembrane and coiled-coil domain protein 3 that is encoded in the genome of human.


KCNS2_HUMAN Potassium voltage-gated channel subfamily S member 2 (sprot)

A voltage-gated potassium channel KCNS2 that is encoded in the genome of human.


TTC7A_HUMAN Tetratricopeptide repeat protein 7A (sprot)

A tetratricopeptide repeat protein 7A that is encoded in the genome of human.


ZNRF3_HUMAN E3 ubiquitin-protein ligase ZNRF3 (sprot)

An E3 ubiquitin-protein ligase ZNRF3 that is encoded in the genome of human.


HECD1_HUMAN E3 ubiquitin-protein ligase HECTD1 (sprot)

An E3 ubiquitin-protein ligase HECTD1 that is encoded in the genome of human.


ZMYD8_HUMAN MYND-type zinc finger-containing chromatin reader ZMYND8 (sprot)

A protein kinase C-binding protein 1 that is encoded in the genome of human.


CAPS1_HUMAN Calcium-dependent secretion activator 1 (sprot)

A calcium-dependent secretion activator 1 that is encoded in the genome of human.


MYO5B_HUMAN Unconventional myosin-Vb (sprot)

A myosin-Vb that is encoded in the genome of human.


FZD4_HUMAN Frizzled-4 (sprot)

A frizzled-4 that is encoded in the genome of human.


cerebellum vasculature morphogenesis

The process in which the vasculature of the cerebellum is generated and organized.


CIZ1_HUMAN Cip1-interacting zinc finger protein (sprot)

A Cip1-interacting zinc finger protein that is encoded in the genome of human.


COR1C_HUMAN Coronin-1C (sprot)

A coronin-1C that is encoded in the genome of human.


HSF4_HUMAN Heat shock factor protein 4 (sprot)

A heat shock factor protein 4 that is encoded in the genome of human.


CBLC_HUMAN E3 ubiquitin-protein ligase CBL-C (sprot)

An E3 ubiquitin-protein ligase CBL-C that is encoded in the genome of human.


TPX2_HUMAN Targeting protein for Xklp2 (sprot)

A targeting protein for Xklp2 that is encoded in the genome of human.


FZD10_HUMAN Frizzled-10 (sprot)

A frizzled-10 that is encoded in the genome of human.


ABT1_HUMAN Activator of basal transcription 1 (sprot)

An activator of basal transcription 1 that is encoded in the genome of human.


RAB26_HUMAN Ras-related protein Rab-26 (sprot)

A Ras-related protein Rab-26 that is encoded in the genome of human.


exocrine system development

Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.


NP1L2_HUMAN Nucleosome assembly protein 1-like 2 (sprot)

A nucleosome assembly protein 1-like 2 that is encoded in the genome of human.


PADI3_HUMAN Protein-arginine deiminase type-3 (sprot)

A protein-arginine deiminase type-3 that is encoded in the genome of human.


NOB1_HUMAN RNA-binding protein NOB1 (sprot)

An RNA-binding protein NOB1 that is encoded in the genome of human.


RN112_HUMAN RING finger protein 112 (sprot)

A RING finger protein 112 that is encoded in the genome of human.


AKP8L_HUMAN A-kinase anchor protein 8-like (sprot)

An A-kinase anchor protein 8-like that is encoded in the genome of human.


CAH14_HUMAN Carbonic anhydrase 14 (sprot)

A carbonic anhydrase 14 that is encoded in the genome of human.


MAFF_HUMAN Transcription factor MafF (sprot)

A transcription factor MafF that is encoded in the genome of human.


CLC4E_HUMAN C-type lectin domain family 4 member E (sprot)

A C-type lectin domain family 4 member E that is encoded in the genome of human.


T53G3_HUMAN TP53-target gene 3 protein (sprot)

A TP53-target gene 3 protein that is encoded in the genome of human.


APEL_HUMAN Apelin (sprot)

An apelin that is encoded in the genome of human.


STAP1_HUMAN Signal-transducing adaptor protein 1 (sprot)

A signal-transducing adaptor protein 1 that is encoded in the genome of human.


negative regulation of microglial cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.


ASC_HUMAN Apoptosis-associated speck-like protein containing a CARD (sprot)

An apoptosis-associated speck-like protein containing a CARD that is encoded in the genome of human.


myosin I binding

Binding to a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments.


MMP17_HUMAN Matrix metalloproteinase-17 (sprot)

A matrix metalloproteinase-17 that is encoded in the genome of human.


TMCO1_HUMAN Calcium load-activated calcium channel (sprot)

A calcium load-activated calcium channel that is encoded in the genome of human.


YLAT1_HUMAN Y+L amino acid transporter 1 (sprot)

A Y+L amino acid transporter 1 that is encoded in the genome of human.


PADI4_HUMAN Protein-arginine deiminase type-4 (sprot)

A protein-arginine deiminase type-4 that is encoded in the genome of human.


histone arginine deiminase activity

Catalysis of the reaction: H2O + histone 3 L-arginyl = histone 3 L-citrullyl + NH4+, resulting in histone citrullination.


histone H3R2 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl (position 2)= histone H3 L-citrullyl (position 2) + NH4+, resulting in histone H3 citrullination at position 2.


histone H3R8 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl (position 8)= histone H3 L-citrullyl (position 8) + NH4+, resulting in histone H3 citrullination at position 8.


histone H3R17 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl (position 17)= histone H3 L-citrullyl (position 17) + NH4+, resulting in histone H3 citrullination at position 17.


histone H3R26 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl (position 26)= histone H3 L-citrullyl (position 26) + NH4+, resulting in histone H3 citrullination at position 26.


FZR1_HUMAN Fizzy-related protein homolog (sprot)

A fizzy-related protein that is encoded in the genome of human.


APC10_HUMAN Anaphase-promoting complex subunit 10 (sprot)

An anaphase-promoting complex subunit 10 that is encoded in the genome of human.


HPCL4_HUMAN Hippocalcin-like protein 4 (sprot)

A hippocalcin-like protein 4 that is encoded in the genome of human.


MGT4A_HUMAN Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (sprot)

An alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A that is encoded in the genome of human.


EPDR1_HUMAN Mammalian ependymin-related protein 1 (sprot)

A mammalian ependymin-related protein 1 that is encoded in the genome of human.


HHLA2_HUMAN HERV-H LTR-associating protein 2 (sprot)

A HERV-H LTR-associating protein 2 that is encoded in the genome of human.


NOTC3_HUMAN Neurogenic locus notch homolog protein 3 (sprot)

A neurogenic locus notch homolog protein 3 that is encoded in the genome of human.


MYO6_HUMAN Unconventional myosin-VI (sprot)

A myosin-VI that is encoded in the genome of human.


minus-end directed microfilament motor activity

A motor activity that generates movement along a microfilament towards the minus end, driven by ATP hydrolysis. The minus end of an actin filament is the end that does not preferentially add actin monomers.


regulation of secretion

Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.


PLAL1_HUMAN Zinc finger protein PLAGL1 (sprot)

A zinc finger protein PLAGL1 that is encoded in the genome of human.


ALK_HUMAN ALK tyrosine kinase receptor (sprot)

An ALK tyrosine kinase receptor that is encoded in the genome of human.


response to environmental enrichment

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.


SPAT2_HUMAN Spermatogenesis-associated protein 2 (sprot)

A spermatogenesis-associated protein 2 that is encoded in the genome of human.


COHA1_HUMAN Collagen alpha-1(XVII) chain (sprot)

A collagen alpha-1(XVII) chain that is encoded in the genome of human.


ICAM5_HUMAN Intercellular adhesion molecule 5 (sprot)

An intercellular adhesion molecule 5 that is encoded in the genome of human.


KMT2B_HUMAN Histone-lysine N-methyltransferase 2B (sprot)

A histone-lysine N-methyltransferase 2B that is encoded in the genome of human.


BARX2_HUMAN Homeobox protein BarH-like 2 (sprot)

A homeobox protein BarH-like 2 that is encoded in the genome of human.


CAN11_HUMAN Calpain-11 (sprot)

A calpain-11 that is encoded in the genome of human.


DD19B_HUMAN ATP-dependent RNA helicase DDX19B (sprot)

An ATP-dependent RNA helicase DDX19B that is encoded in the genome of human.


TBX20_HUMAN T-box transcription factor TBX20 (sprot)

A T-box transcription factor TBX20 that is encoded in the genome of human.


tricuspid valve development

The progression of the tricuspid valve over time, from its formation to the mature structure.


foramen ovale closure

The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.


embryonic heart tube elongation

The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.


lateral mesoderm formation

The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.


pulmonary vein morphogenesis

The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.


PPT2_HUMAN Lysosomal thioesterase PPT2 (sprot)

A lysosomal thioesterase PPT2 that is encoded in the genome of human.


palmitoyl hydrolase activity

Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.


CLC4A_HUMAN C-type lectin domain family 4 member A (sprot)

A C-type lectin domain family 4 member A that is encoded in the genome of human.


plasmacytoid dendritic cell antigen processing and presentation

The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


NFU1_HUMAN NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (sprot)

An NFU1 iron-sulfur cluster scaffold, mitochondrial that is encoded in the genome of human.


PRP19_HUMAN Pre-mRNA-processing factor 19 (sprot)

A pre-mRNA-processing factor 19 that is encoded in the genome of human.


PHTF1_HUMAN Protein PHTF1 (sprot)

A protein PHTF1 that is encoded in the genome of human.


SYNP2_HUMAN Synaptopodin-2 (sprot)

A synaptopodin-2 that is encoded in the genome of human.


UBP18_HUMAN Ubl carboxyl-terminal hydrolase 18 (sprot)

A Ubl carboxyl-terminal hydrolase 18 that is encoded in the genome of human.


UBQL1_HUMAN Ubiquilin-1 (sprot)

A ubiquilin-1 that is encoded in the genome of human.


negative regulation of store-operated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.


SUFU_HUMAN Suppressor of fused homolog (sprot)

A suppressor of fused homolog that is encoded in the genome of human.


positive regulation of cellular response to drug

Any process that activates or increases the frequency, rate or extent of cellular response to drug.


OAZ3_HUMAN Ornithine decarboxylase antizyme 3 (sprot)

An ornithine decarboxylase antizyme 3 that is encoded in the genome of human.


BOK_HUMAN Bcl-2-related ovarian killer protein (sprot)

A Bcl-2-related ovarian killer protein that is encoded in the genome of human.


NENF_HUMAN Neudesin (sprot)

A neudesin that is encoded in the genome of human.


GUC1B_HUMAN Guanylyl cyclase-activating protein 2 (sprot)

A guanylyl cyclase-activating protein 2 that is encoded in the genome of human.


S45A2_HUMAN Membrane-associated transporter protein (sprot)

A membrane-associated transporter protein that is encoded in the genome of human.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.


NOL7_HUMAN Nucleolar protein 7 (sprot)

A nucleolar protein 7 that is encoded in the genome of human.


SNX12_HUMAN Sorting nexin-12 (sprot)

A sorting nexin-12 that is encoded in the genome of human.


SYNRG_HUMAN Synergin gamma (sprot)

A synergin gamma that is encoded in the genome of human.


PTPRQ_HUMAN Phosphatidylinositol phosphatase PTPRQ (sprot)

A phosphotidylinositol phosphatase PTPRQ that is encoded in the genome of human.


DAPP1_HUMAN Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (sprot)

A dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide that is encoded in the genome of human.


NDRG2_HUMAN Protein NDRG2 (sprot)

A protein NDRG2 that is encoded in the genome of human.


regulation of platelet-derived growth factor production

Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


VPS4A_HUMAN Vacuolar protein sorting-associated protein 4A (sprot)

A vacuolar protein sorting-associated protein 4A that is encoded in the genome of human.


actomyosin contractile ring contraction

The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.


vesicle uncoating

A protein depolymerization process that results in the disassembly of vesicle coat proteins.


ESCRT complex disassembly

The disaggregation of an ESCRT complex into its constituent components.


AT1B4_HUMAN Protein ATP1B4 (sprot)

A protein ATP1B4 that is encoded in the genome of human.


PCDB8_HUMAN Protocadherin beta-8 (sprot)

A protocadherin beta-8 that is encoded in the genome of human.


PCDBA_HUMAN Protocadherin beta-10 (sprot)

A protocadherin beta-10 that is encoded in the genome of human.


PCDGK_HUMAN Protocadherin gamma-C3 (sprot)

A protocadherin gamma-C3 that is encoded in the genome of human.


PCDGG_HUMAN Protocadherin gamma-B4 (sprot)

A protocadherin gamma-B4 that is encoded in the genome of human.


PCDA7_HUMAN Protocadherin alpha-7 (sprot)

A protocadherin alpha-7 that is encoded in the genome of human.


PCDA6_HUMAN Protocadherin alpha-6 (sprot)

A protocadherin alpha-6 that is encoded in the genome of human.


PCDA4_HUMAN Protocadherin alpha-4 (sprot)

A protocadherin alpha-4 that is encoded in the genome of human.


PCDAC_HUMAN Protocadherin alpha-12 (sprot)

A protocadherin alpha-12 that is encoded in the genome of human.


S6A14_HUMAN Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (sprot)

A sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) that is encoded in the genome of human.


beta-alanine transmembrane transporter activity

Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.


neutral, basic amino acid:sodium:chloride symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in).


SOX13_HUMAN Transcription factor SOX-13 (sprot)

A transcription factor SOX-13 that is encoded in the genome of human.


LORF1_HUMAN LINE-1 retrotransposable element ORF1 protein (sprot)


G3BP2_HUMAN Ras GTPase-activating protein-binding protein 2 (sprot)

A Ras GTPase-activating protein-binding protein 2 that is encoded in the genome of human.


GBRT_HUMAN Gamma-aminobutyric acid receptor subunit theta (sprot)

A gamma-aminobutyric acid receptor subunit theta that is encoded in the genome of human.


ATS5_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 5 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 5 that is encoded in the genome of human.


RHG26_HUMAN Rho GTPase-activating protein 26 (sprot)

A Rho GTPase-activating protein 26 that is encoded in the genome of human.


An alpha-1,4-N-acetylglucosaminyltransferase that is encoded in the genome of human.


POLI_HUMAN DNA polymerase iota (sprot)

A DNA polymerase iota that is encoded in the genome of human.


NPIA1_HUMAN Nuclear pore complex-interacting protein family member A1 (sprot)

A nuclear pore complex-interacting protein family member A1 that is encoded in the genome of human.


EDAR_HUMAN Tumor necrosis factor receptor superfamily member EDAR (sprot)

A tumor necrosis factor receptor superfamily member EDAR that is encoded in the genome of human.


RPH3L_HUMAN Rab effector Noc2 (sprot)

A Rab effector Noc2 that is encoded in the genome of human.


CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (sprot)

An E3 ubiquitin-protein ligase CHIP that is encoded in the genome of human.


positive regulation of chaperone-mediated protein complex assembly

Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.


PACN2_HUMAN Protein kinase C and casein kinase substrate in neurons protein 2 (sprot)

A protein kinase C and casein kinase substrate in neurons protein 2 that is encoded in the genome of human.


MAGD2_HUMAN Melanoma-associated antigen D2 (sprot)

A melanoma-associated antigen D2 that is encoded in the genome of human.


TNF18_HUMAN Tumor necrosis factor ligand superfamily member 18 (sprot)

A tumor necrosis factor ligand superfamily member 18 that is encoded in the genome of human.


CC14A_HUMAN Dual specificity protein phosphatase CDC14A (sprot)

A dual specificity protein phosphatase CDC14A that is encoded in the genome of human.


SNX7_HUMAN Sorting nexin-7 (sprot)

A sorting nexin-7 that is encoded in the genome of human.


SNX6_HUMAN Sorting nexin-6 (sprot)

A sorting nexin-6 that is encoded in the genome of human.


CELA1_HUMAN Chymotrypsin-like elastase family member 1 (sprot)

A chymotrypsin-like elastase family member 1 that is encoded in the genome of human.


DUS12_HUMAN Dual specificity protein phosphatase 12 (sprot)

A dual specificity protein phosphatase 12 that is encoded in the genome of human.


STX8_HUMAN Syntaxin-8 (sprot)

A syntaxin-8 that is encoded in the genome of human.


PA2GD_HUMAN Group IID secretory phospholipase A2 (sprot)

A group IID secretory phospholipase A2 that is encoded in the genome of human.


regulation of acute inflammatory response to antigenic stimulus

Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


ANGE1_HUMAN Protein angel homolog 1 (sprot)

A protein angel homolog 1 that is encoded in the genome of human.


SSRG_HUMAN Translocon-associated protein subunit gamma (sprot)

A translocon-associated protein subunit gamma that is encoded in the genome of human.


ING4_HUMAN Inhibitor of growth protein 4 (sprot)

An inhibitor of growth protein 4 that is encoded in the genome of human.


PSD13_HUMAN 26S proteasome non-ATPase regulatory subunit 13 (sprot)

A 26S proteasome non-ATPase regulatory subunit 13 that is encoded in the genome of human.


TF2AY_HUMAN TFIIA-alpha and beta-like factor (sprot)

A TFIIA-alpha and beta-like factor that is encoded in the genome of human.


FAF1_HUMAN FAS-associated factor 1 (sprot)

A FAS-associated factor 1 that is encoded in the genome of human.


EPCR_HUMAN Endothelial protein C receptor (sprot)

An endothelial protein C receptor that is encoded in the genome of human.


SIAT9_HUMAN Lactosylceramide alpha-2,3-sialyltransferase (sprot)

A lactosylceramide alpha-2,3-sialyltransferase that is encoded in the genome of human.


Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.


PPIE_HUMAN Peptidyl-prolyl cis-trans isomerase E (sprot)

A peptidyl-prolyl cis-trans isomerase E that is encoded in the genome of human.


ABCG2_HUMAN Broad substrate specificity ATP-binding cassette transporter ABCG2 (sprot)

A broad substrate specificity ATP-binding cassette transporter ABCG2 that is encoded in the genome of human.


DIM1_HUMAN Probable dimethyladenosine transferase (sprot)

A probable dimethyladenosine transferase that is encoded in the genome of human.


18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA.


TIM_HUMAN Protein timeless homolog (sprot)

A protein timeless that is encoded in the genome of human.


CSN3_HUMAN COP9 signalosome complex subunit 3 (sprot)

A COP9 signalosome complex subunit 3 that is encoded in the genome of human.


regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.


RBL2B_HUMAN Rab-like protein 2B (sprot)

A Rab-like protein 2B that is encoded in the genome of human.


CP8B1_HUMAN 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (sprot)

A cytochrome P450 8B1 that is encoded in the genome of human.


sterol 12-alpha-hydroxylase activity

Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O.


Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H+ + NADPH + O2 = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H2O + NADP+.


Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H+ + NADPH + O2 = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H2O + NADP+.


MINP1_HUMAN Multiple inositol polyphosphate phosphatase 1 (sprot)

A multiple inositol polyphosphate phosphatase 1 that is encoded in the genome of human.


Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate.


Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate.


Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.


Catalysis of the reaction: (2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate.


inositol hexakisphosphate 2-phosphatase activity

Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate.


inositol pentakisphosphate phosphatase activity

Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.


GP132_HUMAN Probable G-protein coupled receptor 132 (sprot)

A probable G-protein coupled receptor 132 that is encoded in the genome of human.


NOVA2_HUMAN RNA-binding protein Nova-2 (sprot)

An RNA-binding protein Nova-2 that is encoded in the genome of human.


RL26L_HUMAN Ribosomal protein uL24-like (sprot)

A 60S ribosomal protein L26-like 1 that is encoded in the genome of human.


WDR3_HUMAN WD repeat-containing protein 3 (sprot)

A WD repeat-containing protein 3 that is encoded in the genome of human.


KCJ14_HUMAN ATP-sensitive inward rectifier potassium channel 14 (sprot)

An ATP-sensitive inward rectifier potassium channel 14 that is encoded in the genome of human.


TTF2_HUMAN Transcription termination factor 2 (sprot)

A transcription termination factor 2 that is encoded in the genome of human.


ZN232_HUMAN Zinc finger protein 232 (sprot)

A zinc finger protein 232 that is encoded in the genome of human.


NSF1C_HUMAN NSFL1 cofactor p47 (sprot)

An NSFL1 cofactor p47 that is encoded in the genome of human.


FZD1_HUMAN Frizzled-1 (sprot)

A frizzled-1 that is encoded in the genome of human.


TFR2_HUMAN Transferrin receptor protein 2 (sprot)

A transferrin receptor protein 2 that is encoded in the genome of human.


endocytic iron import into cell

Uptake of iron into a cell via binding to an extracellular receptor, which is internalized by endocytosis.


positive regulation of protein maturation

Any process that activates or increases the frequency, rate or extent of protein maturation.


PA24C_HUMAN Cytosolic phospholipase A2 gamma (sprot)

A cytosolic phospholipase A2 gamma that is encoded in the genome of human.


ATS8_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 8 (sprot)

An a disintegrin and metalloproteinase with thrombospondin motifs 8 that is encoded in the genome of human.


low-affinity phosphate transmembrane transporter activity

Enables the transfer of phosphate from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


COG5_HUMAN Conserved oligomeric Golgi complex subunit 5 (sprot)

A conserved oligomeric Golgi complex subunit 5 that is encoded in the genome of human.


inter-Golgi cisterna vesicle-mediated transport

The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.


S12A4_HUMAN Solute carrier family 12 member 4 (sprot)

A solute carrier family 12 member 4 that is encoded in the genome of human.


BSN_HUMAN Protein bassoon (sprot)

A protein bassoon that is encoded in the genome of human.


presynapse to nucleus signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).


cytoskeleton of presynaptic active zone

The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.


GPR34_HUMAN Probable G-protein coupled receptor 34 (sprot)

A probable G-protein coupled receptor 34 that is encoded in the genome of human.


SRPK3_HUMAN SRSF protein kinase 3 (sprot)

An SRSF protein kinase 3 that is encoded in the genome of human.


PLAL2_HUMAN Zinc finger protein PLAGL2 (sprot)

A zinc finger protein PLAGL2 that is encoded in the genome of human.


FLVC2_HUMAN Heme transporter FLVCR2 (sprot)

A feline leukemia virus subgroup C receptor-related protein 2 that is encoded in the genome of human.


LHX6_HUMAN LIM/homeobox protein Lhx6 (sprot)

A LIM/homeobox protein Lhx6 that is encoded in the genome of human.


AP4E1_HUMAN AP-4 complex subunit epsilon-1 (sprot)

An AP-4 complex subunit epsilon-1 that is encoded in the genome of human.


B9D1_HUMAN B9 domain-containing protein 1 (sprot)

A B9 domain-containing protein 1 that is encoded in the genome of human.


hedgehog receptor activity

Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.


MACF1_HUMAN Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (sprot)

A microtubule-actin cross-linking factor 1 that is encoded in the genome of human.


CP131_HUMAN Centrosomal protein of 131 kDa (sprot)

A centrosomal protein of 131 kDa that is encoded in the genome of human.


sperm head-tail coupling apparatus

A centrosome-based structure consisting of two cylindrical microtubule-based centrioles and associated components which anchors the flagellum to the sperm head.


SCAF8_HUMAN SR-related and CTD-associated factor 8 (sprot)

An SR-related and CTD-associated factor 8 that is encoded in the genome of human.


PP6R1_HUMAN Serine/threonine-protein phosphatase 6 regulatory subunit 1 (sprot)

A serine/threonine-protein phosphatase 6 regulatory subunit 1 that is encoded in the genome of human.


TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (sprot)

An E3 ubiquitin-protein ligase TRIM33 that is encoded in the genome of human.


PHF8_HUMAN Histone lysine demethylase PHF8 (sprot)

A histone lysine demethylase PHF8 that is encoded in the genome of human.


IQEC3_HUMAN IQ motif and SEC7 domain-containing protein 3 (sprot)

An IQ motif and SEC7 domain-containing protein 3 that is encoded in the genome of human.


LIMC1_HUMAN LIM and calponin homology domains-containing protein 1 (sprot)

A LIM and calponin homology domains-containing protein 1 that is encoded in the genome of human.


myosin II head/neck binding

Binding to the head/neck region of a myosin II heavy chain.


AGAP1_HUMAN Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (sprot)

An Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 that is encoded in the genome of human.


TRI35_HUMAN E3 ubiquitin-protein ligase TRIM35 (sprot)

An E3 ubiquitin-protein ligase TRIM35 that is encoded in the genome of human.


PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN3 (sprot)

An E3 ubiquitin-protein ligase PDZRN3 that is encoded in the genome of human.


DOLK_HUMAN Dolichol kinase (sprot)

A dolichol kinase that is encoded in the genome of human.


dolichol kinase activity

Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.


dolichyl monophosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative.


TNR6B_HUMAN Trinucleotide repeat-containing gene 6B protein (sprot)

A trinucleotide repeat-containing gene 6B protein that is encoded in the genome of human.


PLCL2_HUMAN Inactive phospholipase C-like protein 2 (sprot)

An inactive phospholipase C-like protein 2 that is encoded in the genome of human.


SMG5_HUMAN Nonsense-mediated mRNA decay factor SMG5 (sprot)

A nonsense-mediated mRNA decay factor SMG5 that is encoded in the genome of human.


NAC2_HUMAN Sodium/calcium exchanger 2 (sprot)

A sodium/calcium exchanger 2 that is encoded in the genome of human.


regulation of calcineurin-mediated signaling

Any process that modulates the frequency, rate or extent of calcineurin-mediated signaling.


regulation of action potential firing pattern

Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.


calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.


ZFR2_HUMAN Zinc finger RNA-binding protein 2 (sprot)

A zinc finger RNA-binding protein 2 that is encoded in the genome of human.


SET1B_HUMAN Histone-lysine N-methyltransferase SETD1B (sprot)

A histone-lysine N-methyltransferase SETD1B that is encoded in the genome of human.


ANR26_HUMAN Ankyrin repeat domain-containing protein 26 (sprot)

An ankyrin repeat domain-containing protein 26 that is encoded in the genome of human.


EXOC7_HUMAN Exocyst complex component 7 (sprot)

An exocyst complex component 7 that is encoded in the genome of human.


JIP3_HUMAN C-Jun-amino-terminal kinase-interacting protein 3 (sprot)

A C-Jun-amino-terminal kinase-interacting protein 3 that is encoded in the genome of human.


ZC3H4_HUMAN Zinc finger CCCH domain-containing protein 4 (sprot)

A zinc finger CCCH domain-containing protein 4 that is encoded in the genome of human.


UBP22_HUMAN Ubiquitin carboxyl-terminal hydrolase 22 (sprot)

A ubiquitin carboxyl-terminal hydrolase 22 that is encoded in the genome of human.


SORC3_HUMAN VPS10 domain-containing receptor SorCS3 (sprot)

A VPS10 domain-containing receptor SorCS3 that is encoded in the genome of human.


UBP24_HUMAN Ubiquitin carboxyl-terminal hydrolase 24 (sprot)

A ubiquitin carboxyl-terminal hydrolase 24 that is encoded in the genome of human.


TBD2B_HUMAN TBC1 domain family member 2B (sprot)

A TBC1 domain family member 2B that is encoded in the genome of human.


SMAG1_HUMAN Protein Smaug homolog 1 (sprot)

A protein Smaug homolog 1 that is encoded in the genome of human.


CE164_HUMAN Centrosomal protein of 164 kDa (sprot)

A centrosomal protein of 164 kDa that is encoded in the genome of human.


PHF24_HUMAN PHD finger protein 24 (sprot)

A PHD finger protein 24 that is encoded in the genome of human.


TRAK1_HUMAN Trafficking kinesin-binding protein 1 (sprot)

A trafficking kinesin-binding protein 1 that is encoded in the genome of human.


FOXJ3_HUMAN Forkhead box protein J3 (sprot)

A forkhead box protein J3 that is encoded in the genome of human.


CBPC1_HUMAN Cytosolic carboxypeptidase 1 (sprot)

A cytosolic carboxypeptidase 1 that is encoded in the genome of human.


SATB2_HUMAN DNA-binding protein SATB2 (sprot)

A DNA-binding protein SATB2 that is encoded in the genome of human.


UN13A_HUMAN Protein unc-13 homolog A (sprot)

A protein unc-13 homolog A that is encoded in the genome of human.


TUTLB_HUMAN Protein turtle homolog B (sprot)

A protein turtle homolog B that is encoded in the genome of human.


MNAR1_HUMAN Major intrinsically disordered Notch2-binding receptor 1 (sprot)

A major intrinsically disordered Notch2-binding receptor 1 that is encoded in the genome of human.


SHAN2_HUMAN SH3 and multiple ankyrin repeat domains protein 2 (sprot)

An SH3 and multiple ankyrin repeat domains protein 2 that is encoded in the genome of human.


DICER_HUMAN Endoribonuclease Dicer (sprot)

An endoribonuclease Dicer that is encoded in the genome of human.


XCT_HUMAN Cystine/glutamate transporter (sprot)

A cystine/glutamate transporter that is encoded in the genome of human.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).


L-kynurenine transmembrane transporter activity

Enables the transfer of L-kynurenine from one side of a membrane to the other.


regulation of neutrophil apoptotic process

Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.


L-kynurenine transmembrane transport

The directed movement of L-kynurenine across a membrane.


regulation of cysteine metabolic process

Any process that modulates the frequency, rate or extent of cysteine metabolic process.


regulation of glutathione biosynthetic process

Any process that modulates the frequency, rate or extent of glutathione biosynthetic process.


regulation of glutamate metabolic process

Any process that modulates the frequency, rate or extent of glutamate metabolic process.


WASF3_HUMAN Actin-binding protein WASF3 (sprot)

An actin-binding protein WASF3 that is encoded in the genome of human.


MARE3_HUMAN Microtubule-associated protein RP/EB family member 3 (sprot)

A microtubule-associated protein RP/EB family member 3 that is encoded in the genome of human.


HPS5_HUMAN BLOC-2 complex member HPS5 (sprot)

A BLOC-2 complex member HPS5 that is encoded in the genome of human.


THS7A_HUMAN Thrombospondin type-1 domain-containing protein 7A (sprot)

A thrombospondin type-1 domain-containing protein 7A that is encoded in the genome of human.


CILK1_HUMAN Serine/threonine-protein kinase ICK (sprot)

A serine/threonine-protein kinase ICK that is encoded in the genome of human.


COR2B_HUMAN Coronin-2B (sprot)

A coronin-2B that is encoded in the genome of human.


negative regulation of establishment of protein localization

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.


talin binding

Binding to a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.


KCNH4_HUMAN Potassium voltage-gated channel subfamily H member 4 (sprot)

A voltage-gated potassium channel KCNH4 that is encoded in the genome of human.


MOK_HUMAN MAPK/MAK/MRK overlapping kinase (sprot)

A MAPK/MAK/MRK overlapping kinase that is encoded in the genome of human.


DHDH_HUMAN Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (sprot)

A trans-1,2-dihydrobenzene-1,2-diol dehydrogenase that is encoded in the genome of human.


SHOC2_HUMAN Leucine-rich repeat protein SHOC-2 (sprot)

A leucine-rich repeat protein SHOC-2 that is encoded in the genome of human.


cellular response to growth hormone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.


DYN3_HUMAN Dynamin-3 (sprot)

A dynamin-3 that is encoded in the genome of human.


type 1 metabotropic glutamate receptor binding

Binding to a type 1 metabotropic glutamate receptor.


positive regulation of synaptic vesicle recycling

Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.


postsynaptic endocytic zone membrane

The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta.


apical tubulobulbar complex

Actin-based structures involved in establishing close contact between mature spermatids and Sertoli cells at the luminal end of the Sertoli cell.


basal tubulobulbar complex

Actin-based structures involved in establishing the blood-testis barrier of the Sertoli cell.


RIMS2_HUMAN Regulating synaptic membrane exocytosis protein 2 (sprot)

A regulating synaptic membrane exocytosis protein 2 that is encoded in the genome of human.


SRRM2_HUMAN Serine/arginine repetitive matrix protein 2 (sprot)

A serine/arginine repetitive matrix protein 2 that is encoded in the genome of human.


NEUR3_HUMAN Sialidase-3 (sprot)

A sialidase-3 that is encoded in the genome of human.


CNTN6_HUMAN Contactin-6 (sprot)

A contactin-6 that is encoded in the genome of human.


MGT4B_HUMAN Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (sprot)

An alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B that is encoded in the genome of human.


PSG11_HUMAN Pregnancy-specific beta-1-glycoprotein 11 (sprot)

A pregnancy-specific beta-1-glycoprotein 11 that is encoded in the genome of human.


PSG8_HUMAN Pregnancy-specific beta-1-glycoprotein 8 (sprot)

A pregnancy-specific beta-1-glycoprotein 8 that is encoded in the genome of human.


PA2G4_HUMAN Proliferation-associated protein 2G4 (sprot)

A proliferation-associated protein 2G4 that is encoded in the genome of human.


EXO1_HUMAN Exonuclease 1 (sprot)

An exonuclease 1 that is encoded in the genome of human.


double-stranded DNA 5'-3' exodeoxyribonuclease activity

Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule.


CD11A_HUMAN Cyclin-dependent kinase 11A (sprot)

A cyclin-dependent kinase 11A that is encoded in the genome of human.


SPG7_HUMAN Paraplegin (sprot)

A paraplegin that is encoded in the genome of human.


CTND2_HUMAN Catenin delta-2 (sprot)

A catenin delta-2 that is encoded in the genome of human.


BAIP2_HUMAN Brain-specific angiogenesis inhibitor 1-associated protein 2 (sprot)

A brain-specific angiogenesis inhibitor 1-associated protein 2 that is encoded in the genome of human.


neuron projection branch point

The location where a secondary projection arises from a neuron projection.


dendritic spine cytoplasm

The region of the neuronal cytoplasm located in dendritic spines.


AURKC_HUMAN Aurora kinase C (sprot)

An aurora kinase C that is encoded in the genome of human.


GAB2_HUMAN GRB2-associated-binding protein 2 (sprot)

A GRB2-associated-binding protein 2 that is encoded in the genome of human.


CLCA2_HUMAN Calcium-activated chloride channel regulator 2 (sprot)

A calcium-activated chloride channel regulator 2 that is encoded in the genome of human.


SCN8A_HUMAN Sodium channel protein type 8 subunit alpha (sprot)

A sodium channel protein type 8 subunit alpha that is encoded in the genome of human.


SMC3_HUMAN Structural maintenance of chromosomes protein 3 (sprot)

A structural maintenance of chromosomes protein 3 that is encoded in the genome of human.


SYCY1_HUMAN Syncytin-1 (sprot)

A syncytin-1 that is encoded in the genome of human.


JIP1_HUMAN C-Jun-amino-terminal kinase-interacting protein 1 (sprot)

A C-Jun-amino-terminal kinase-interacting protein 1 that is encoded in the genome of human.


dentate gyrus mossy fiber

Distinctive, unmyelinated axons produced by dentate gyrus granule cells.


POK11_HUMAN Endogenous retrovirus group K member 11 Pol protein (sprot)

A protein that is a translation product of the ERVK-11 gene in human.


PPR3C_HUMAN Protein phosphatase 1 regulatory subunit 3C (sprot)

A protein phosphatase 1 regulatory subunit 3C that is encoded in the genome of human.


HDAC5_HUMAN Histone deacetylase 5 (sprot)

A histone deacetylase 5 that is encoded in the genome of human.


KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha (sprot)

A calcium/calmodulin-dependent protein kinase type II subunit alpha that is encoded in the genome of human.


peptidyl-threonine autophosphorylation

The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.


CHM2B_HUMAN Charged multivesicular body protein 2b (sprot)

A charged multivesicular body protein 2b that is encoded in the genome of human.


TENN_HUMAN Tenascin-N (sprot)

A tenascin-N that is encoded in the genome of human.


regulation of smooth muscle tissue development

Any process that modulates the frequency, rate or extent of smooth muscle tissue development.


NALDL_HUMAN Aminopeptidase NAALADL1 (sprot)

An aminopeptidase NAALADL1 that is encoded in the genome of human.


SH2B3_HUMAN SH2B adapter protein 3 (sprot)

An SH2B adapter protein 3 that is encoded in the genome of human.


SCML2_HUMAN Sex comb on midleg-like protein 2 (sprot)

A sex comb on midleg-like protein 2 that is encoded in the genome of human.


ZN148_HUMAN Zinc finger protein 148 (sprot)

A zinc finger protein 148 that is encoded in the genome of human.


LAMP3_HUMAN Lysosome-associated membrane glycoprotein 3 (sprot)

A lysosome-associated membrane glycoprotein 3 that is encoded in the genome of human.


regulation of viral life cycle

Any process that modulates the frequency, rate or extent of viral life cycle.


POK19_HUMAN Endogenous retrovirus group K member 19 Pol protein (sprot)


HHLA3_HUMAN Putative uncharacterized protein ANKRD13C-DT (sprot)

A HERV-H LTR-associating protein 3 that is encoded in the genome of human.


TRPC6_HUMAN Short transient receptor potential channel 6 (sprot)

A short transient receptor potential channel 6 that is encoded in the genome of human.


COLQ_HUMAN Acetylcholinesterase collagenic tail peptide (sprot)

An acetylcholinesterase collagenic tail peptide that is encoded in the genome of human.


MTMR7_HUMAN Myotubularin-related protein 7 (sprot)

A myotubularin-related protein 7 that is encoded in the genome of human.


MTMR6_HUMAN Myotubularin-related protein 6 (sprot)

A myotubularin-related protein 6 that is encoded in the genome of human.


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.


JAG2_HUMAN Protein jagged-2 (sprot)

A protein jagged-2 that is encoded in the genome of human.


epithelial cell apoptotic process involved in palatal shelf morphogenesis

An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.


NIP7_HUMAN 60S ribosome subunit biogenesis protein NIP7 homolog (sprot)

A 60S ribosome subunit biogenesis protein NIP7 that is encoded in the genome of human.


DMTF1_HUMAN Cyclin-D-binding Myb-like transcription factor 1 (sprot)

A cyclin-D-binding Myb-like transcription factor 1 that is encoded in the genome of human.


GLCNE_HUMAN Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (sprot)

A bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase that is encoded in the genome of human.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.


N-acylmannosamine kinase activity

Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.


RTRAF_HUMAN RNA transcription, translation and transport factor protein (sprot)

A protein C14orf166 that is encoded in the genome of human.


RNF24_HUMAN RING finger protein 24 (sprot)

A RING finger protein 24 that is encoded in the genome of human.


S22AD_HUMAN Solute carrier family 22 member 13 (sprot)

A solute carrier family 22 member 13 that is encoded in the genome of human.


nicotinate transmembrane transporter activity

Enables the transfer of nicotinate from one side of a membrane to the other.


ENTP4_HUMAN Ectonucleoside triphosphate diphosphohydrolase 4 (sprot)

An ectonucleoside triphosphate diphosphohydrolase 4 that is encoded in the genome of human.


CTP metabolic process

The chemical reactions and pathways involving CTP, cytidine triphosphate.


T3JAM_HUMAN TRAF3-interacting JNK-activating modulator (sprot)

A TRAF3-interacting JNK-activating modulator that is encoded in the genome of human.


RUVB2_HUMAN RuvB-like 2 (sprot)

A RuvB-like 2 that is encoded in the genome of human.


FUT9_HUMAN 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 (sprot)

A 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9 that is encoded in the genome of human.


Lewis x epitope biosynthetic process

The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide.


CDYL_HUMAN Chromodomain Y-like protein (sprot)

A chromodomain Y-like protein that is encoded in the genome of human.


negative regulation of peptidyl-lysine crotonylation

Any process that stops or reduces the rate of crotonylation of a lysine residue in a protein.


PDE10_HUMAN cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (sprot)

A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A that is encoded in the genome of human.


LIPT_HUMAN Lipoyltransferase 1, mitochondrial (sprot)

A lipoyltransferase 1, mitochondrial that is encoded in the genome of human.


lipoyltransferase activity

Catalysis of the reaction: (R)-lipoyl-5'-AMP + L-lysyl-[lipoyl-carrier protein] = (R)-N6-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + 2 H+.


ABEC2_HUMAN C->U-editing enzyme APOBEC-2 (sprot)

A C->U-editing enzyme APOBEC-2 that is encoded in the genome of human.


OSGI2_HUMAN Oxidative stress-induced growth inhibitor 2 (sprot)

An oxidative stress-induced growth inhibitor 2 that is encoded in the genome of human.


PIN4_HUMAN Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (sprot)

A peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 that is encoded in the genome of human.


DLEC1_HUMAN Deleted in lung and esophageal cancer protein 1 (sprot)

A deleted in lung and esophageal cancer protein 1 that is encoded in the genome of human.


NOD1_HUMAN Nucleotide-binding oligomerization domain-containing protein 1 (sprot)

A nucleotide-binding oligomerization domain-containing protein 1 that is encoded in the genome of human.


peptide receptor activity

Combining with an extracellular or intracellular peptide to initiate a change in cell activity.


CLC11_HUMAN C-type lectin domain family 11 member A (sprot)

A C-type lectin domain family 11 member A that is encoded in the genome of human.


HIG1A_HUMAN HIG1 domain family member 1A, mitochondrial (sprot)

A HIG1 domain family member 1A that is encoded in the genome of human.


TCF19_HUMAN Transcription factor 19 (sprot)

A transcription factor 19 that is encoded in the genome of human.


AKT3_HUMAN RAC-gamma serine/threonine-protein kinase (sprot)

A RAC-gamma serine/threonine-protein kinase that is encoded in the genome of human.


POMP_HUMAN Proteasome maturation protein (sprot)

A proteasome maturation protein that is encoded in the genome of human.


FA50B_HUMAN Protein FAM50B (sprot)

A protein FAM50B that is encoded in the genome of human.


PSF2_HUMAN DNA replication complex GINS protein PSF2 (sprot)

A DNA replication complex GINS protein PSF2 that is encoded in the genome of human.


LZTS1_HUMAN Leucine zipper putative tumor suppressor 1 (sprot)

A leucine zipper putative tumor suppressor 1 that is encoded in the genome of human.


HPSE_HUMAN Heparanase (sprot)

A heparanase that is encoded in the genome of human.


RNF6_HUMAN E3 ubiquitin-protein ligase RNF6 (sprot)

An E3 ubiquitin-protein ligase RNF6 that is encoded in the genome of human.


POLH_HUMAN DNA polymerase eta (sprot)

A DNA polymerase eta that is encoded in the genome of human.


PRLD1_HUMAN PRELI domain-containing protein 1, mitochondrial (sprot)

A PRELI domain-containing protein 1, mitochondrial that is encoded in the genome of human.


FACE2_HUMAN CAAX prenyl protease 2 (sprot)

A CAAX prenyl protease 2 that is encoded in the genome of human.


KCNK6_HUMAN Potassium channel subfamily K member 6 (sprot)

A potassium channel subfamily K member 6 that is encoded in the genome of human.


CCL26_HUMAN C-C motif chemokine 26 (sprot)

A C-C motif chemokine 26 that is encoded in the genome of human.


CHKB_HUMAN Choline/ethanolamine kinase (sprot)

A choline/ethanolamine kinase that is encoded in the genome of human.


FOXA2_HUMAN Hepatocyte nuclear factor 3-beta (sprot)

A hepatocyte nuclear factor 3-beta that is encoded in the genome of human.


negative regulation of transcription from RNA polymerase II promoter by glucose

Any process involving glucose that decreases the frequency, rate or extent or transcription from an RNA polymerase II promoter.


EIF3L_HUMAN Eukaryotic translation initiation factor 3 subunit L (sprot)

A eukaryotic translation initiation factor 3 subunit L that is encoded in the genome of human.


PLAP_HUMAN Phospholipase A-2-activating protein (sprot)

A phospholipase A-2-activating protein that is encoded in the genome of human.


ANGP4_HUMAN Angiopoietin-4 (sprot)

An angiopoietin-4 that is encoded in the genome of human.


RUVB1_HUMAN RuvB-like 1 (sprot)

A RuvB-like 1 that is encoded in the genome of human.


NUDC_HUMAN Nuclear migration protein nudC (sprot)

A nuclear migration protein nudC that is encoded in the genome of human.


S22AE_HUMAN Solute carrier family 22 member 14 (sprot)

A solute carrier family 22 member 14 that is encoded in the genome of human.


CLTR1_HUMAN Cysteinyl leukotriene receptor 1 (sprot)

A cysteinyl leukotriene receptor 1 that is encoded in the genome of human.


RASD1_HUMAN Dexamethasone-induced Ras-related protein 1 (sprot)

A dexamethasone-induced Ras-related protein 1 that is encoded in the genome of human.


SIA10_HUMAN Type 2 lactosamine alpha-2,3-sialyltransferase (sprot)

A type 2 lactosamine alpha-2,3-sialyltransferase that is encoded in the genome of human.


TN13B_HUMAN Tumor necrosis factor ligand superfamily member 13B (sprot)

A tumor necrosis factor ligand superfamily member 13B that is encoded in the genome of human.


BCS1_HUMAN Mitochondrial chaperone BCS1 (sprot)

A mitochondrial chaperone BCS1 that is encoded in the genome of human.


VDAC3_HUMAN Voltage-dependent anion-selective channel protein 3 (sprot)

A voltage-dependent anion-selective channel protein 3 that is encoded in the genome of human.


HS3S2_HUMAN Heparan sulfate glucosamine 3-O-sulfotransferase 2 (sprot)

A heparan sulfate glucosamine 3-O-sulfotransferase 2 that is encoded in the genome of human.


[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity

Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.


VSIG4_HUMAN V-set and immunoglobulin domain-containing protein 4 (sprot)

A V-set and immunoglobulin domain-containing protein 4 that is encoded in the genome of human.


COF2_HUMAN Cofilin-2 (sprot)

A cofilin-2 that is encoded in the genome of human.


ERGI3_HUMAN Endoplasmic reticulum-Golgi intermediate compartment protein 3 (sprot)

An endoplasmic reticulum-Golgi intermediate compartment protein 3 that is encoded in the genome of human.


INVS_HUMAN Inversin (sprot)

An inversin that is encoded in the genome of human.