carbon-nitrogen lyase activity

Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).


hamamelose kinase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H+.


biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.


negative regulation of ERBB3 signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.


regulation of thioredoxin peroxidase activity

Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity.


(-)-menthol monooxygenase activity

Catalysis of the reaction: (-)-menthol + H+ + NADPH + O2 = 1,4-menthane-3,8-diol + H2O + NADP+.


negative regulation of antigen receptor-mediated signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.


The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.


short-chain fatty acid-CoA ligase activity

Catalysis of the reaction: ATP + a short-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA. A short-chain fatty acid is a fatty acid with an aliphatic tail of less than 6 carbons.


effector-mediated modulation of host defenses by symbiont

A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


stearoyl-[acp] desaturase activity

Catalysis of the reaction: O2 + a stearoyl-[acp] + a reduced ferredoxin = 2 H2O + an oleoyl-[acp] + an oxidized ferredoxin.


negative regulation of hypoxia-inducible factor-1alpha signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.


L-dopa biosynthetic process

The chemical reactions and pathways resulting in the formation of L-dopa.


regulation of positive chemotaxis to cAMP by DIF-2

Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.


Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine.


phosphotransferase activity, nitrogenous group as acceptor

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).


shikimate 3-dehydrogenase (NAD+) activity

Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.


regulation of sevenless signaling pathway

Any process that modulates the frequency, rate or extent of the sevenless signaling pathway.


Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H+.


negative regulation of L-glutamine biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine biosynthesis.


alanine dehydrogenase activity

Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H+.


cheating during chimeric sorocarp development

Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.


female analia development

The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.


mandelate metabolic process

The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.


blood coagulation, extrinsic pathway

A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X.


positive regulation of carbohydrate metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.


cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid

The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.


metanephric glomerular epithelial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.


protein cis-autophosphorylation

The phosphorylation by a protein of one or more of its own amino acid residues.


specification of sepal identity

The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


rRNA (uridine) methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.


regulation of ATP citrate synthase activity

Any process that modulates the frequency, rate or extent of ATP citrate synthase activity.


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate.


modulation by symbiont of host erythrocyte aggregation

Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.


3-hydroxyanthranilate oxidase activity

Catalysis of the reaction: 3-hydroxyanthranilate + O2 = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H2O2.


nicotinamidase activity

Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.


trichloroethylene catabolic process

The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.


fluorescent chlorophyll catabolite monooxygenase (deformylase) activity

Catalysis of the reaction: O2 + primary fluorescent chlorophyll catabolite + reduced [NADPH--hemoprotein reductase] = formate + 2 H+ + oxidized [NADPH--hemoprotein reductase] + primary fluorescent dioxobilin-type chlorophyll catabolite.


ergothioneine transmembrane transporter activity

Enables the transfer of ergothioneine from one side of a membrane to the other.


negative regulation of intracellular lipid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.


negative regulation of R8 cell spacing in compound eye

Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.


Catalysis of the reduction of a peptide-linked oxazoline to oxazole.


Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O2 = CO2 + H+ + mugineate + succinate.


tectospinal tract morphogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.


response to decane

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.


Catalysis of the reaction: dTDP-D-fucose + NADP+ = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H+ + NADPH.


regulation of myofibril size

Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.


W-molybdopterin cofactor metabolic process

The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.


envenomation resulting in positive regulation of mast cell degranulation in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism.


formin-nucleated actin cable organization

A process that results in the assembly, arrangement of constituent parts, or disassembly of a formin-nucleated actin cable.


rolling circle double-stranded viral DNA replication

A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.


malonyltransferase activity

Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule.


germacradienol synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.


regulation of lung ciliated cell differentiation

Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.


genital disc morphogenesis

The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.


[isocitrate dehydrogenase (NADP+)] kinase activity

Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate.


peptidyl-lysine succinylation

The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine.


5' overhang single-stranded DNA endodeoxyribonuclease activity

Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks.


vanillin dehydrogenase activity

Catalysis of the reaction: H2O + NAD+ + vanillin = 2 H+ + NADH + vanillate.


myeloid leukocyte cytokine production

Any process that contributes to cytokine production by a myeloid cell.


post-embryonic anterior midgut (ectodermal) morphogenesis

The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.


peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine

The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.


ABC-type capsular-polysaccharide transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).


ligand-gated monoatomic cation channel activity

Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


negative regulation of cytokinesis, site selection

Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.


heat dissipation

Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.


callose deposition in phloem sieve plate

Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.


acyl glucuronidation

The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).


regulation of dense core granule biogenesis

Any process that modulates the frequency, rate or extent of dense core granule biogenesis.


post-embryonic pelvic fin morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.


salivary gland boundary specification

Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.


pons formation

The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.


6-sulfoquinovose(1-) catabolic process

The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).


positive regulation of toll-like receptor 11 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity

Catalysis of the reaction: 5-HETE + NADP+ = 5-oxo-ETE + NADPH + H+.


muconate cycloisomerase activity

Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.


11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity

Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H+.


protein activation cascade

A sequential series of modifications to a set of proteins where the product of one reaction catalyzes the following reaction, ultimately leading to the generation of a mature protein. Modifications typically include proteolysis or covalent modification, and may also include binding events.


polymannuronate hydrolase activity

Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate.


N-carbamoylsarcosine amidase activity

Catalysis of the reaction: N-carbamoylsarcosine + H2O + 2 H+ = CO2 + NH4 + sarcosine.


positive regulation of neutrophil mediated killing of symbiont cell

Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.


Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.


alpha-keto amide reductase activity

Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.


positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis

Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.


Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride.


ABC-type D-xylose transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in).


histone H3-K4 demethylation, trimethyl-H3-K4-specific

The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.


syncytium formation by mitosis without cytokinesis

The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.


nucleoside transmembrane transporter activity, against a concentration gradient

Enables the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.


protein localization to basal ectoplasmic specialization

A process in which a protein is transported to, or maintained in, a location within a basal ectoplasmic specialization.


regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity

Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.


sesquiterpenoid catabolic process

The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.


beta-L-arabinosidase activity

Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.


germarium-derived egg chamber formation

Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.


defecation rhythm

The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.


modulation by symbiont of ethylene levels in host

The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of peptidoglycan recognition protein signaling pathway

Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.


beak formation

The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.


3,5-xylenol methylhydroxylase activity

Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol.


all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity

Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.


larval locomotory behavior

Locomotory behavior in a larval (immature) organism.


[chondroitin sulfate]-D-glucuronyl 2-O-sulfotransferase activity

Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + [chondroitin-sulfate]-beta-D-glucuronate = adenosine 3',5'-bismonophosphate + [chondroitin-sulfate]-2-O-sulfo-beta-D-glucuronate.


bile-acid 7alpha-dehydratase activity

Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H2O.


positive regulation of establishment or maintenance of cell polarity regulating cell shape

Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.


N-1-naphthylphthalamic acid binding

Binding to N-1-naphthylphthalamic acid, an auxin transport inhibitor.


tyramine-beta hydroxylase activity

Catalysis of the hydroxylation of tyramine to form octopamine.


protein localization involved in acrosome reaction

The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.


thermospermine synthase activity

Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.


protein localization to chloroplast starch grain

A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.


seed development

The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.


negative regulation of cerebral blood circulation

Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation.


box C/D RNA processing

Any process involved in the conversion of a primary box C/D type small RNA transcript into a mature box C/D RNA.


RNA localization to nucleus

A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.


positive regulation of adult somatic muscle development

Any process that increases the rate, frequency or extent of adult somatic muscle development.


envenomation resulting in negative regulation of blood pressure in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism.


negative regulation of compound eye retinal cell programmed cell death

Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.


cellular response to bacteriocin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.


epinephrine catabolic process

The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.


canonical Wnt signaling pathway involved in osteoblast differentiation

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation.


fucosterol-epoxide lyase activity

Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.


Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H+ + urate.


response to mannitol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.


UDP-D-galactose metabolic process

The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.


metaxylem development

The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.


protein N-linked N-acetylglucosaminylation via asparagine

A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.


detection of mechanical stimulus involved in sensory perception of gravity

The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.


averantin metabolic process

The chemical reactions and pathways involving averantin.


regulation of leucophore differentiation

Any process that modulates the frequency, rate or extent of leucophore differentiation.


regulation of cellular response to macrophage colony-stimulating factor stimulus

Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.


detection of glucocorticoid hormone stimulus

The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


central B cell anergy

Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.


establishment of mitochondrion localization by microtubule attachment

The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.


3-ketovalidoxylamine C-N-lyase activity

Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H+.


positive regulation of development of symbiont in host

Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.


sucrose synthase activity

Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.


specification of carpel identity

The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


positive regulation of aecium development

Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.


positive regulation of animal organ morphogenesis

Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis.


positive regulation of leukocyte mediated immunity

Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.


plant-type cell wall cellulose catabolic process

The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.


pregnan-21-ol dehydrogenase (NAD+) activity

Catalysis of the reaction: NAD+ + pregnan-21-ol = H+ + NADH + pregnan-21-al.


zerumbone synthase activity

Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+.


negative regulation of nematode male tail tip morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of nematode male tail tip morphogenesis.


phenylcoumaran benzylic ether reductase activity

Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.


protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in).


mating type determination

Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms.


angioblast cell migration involved in selective angioblast sprouting

The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.


semaphorin-plexin signaling pathway involved in outflow tract morphogenesis

The series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.


germ-line stem-cell niche homeostasis

A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.


plant organ development

Development of a plant organ, a multi-tissue plant structure that forms a functional unit.


negative regulation of voltage-gated sodium channel activity in another organism

Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.


plant epidermal cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell.


negative regulation of D-aspartate import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.


positive regulation of embryonic camera-type eye development

Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.


protein flavinylation

The addition of a flavin group to a protein amino acid.


pyridine-3,4-diol dioxygenase activity

Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate.


induction by symbiont of defense-related host reactive oxygen species production

The activation by a symbiont of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


queuosine nucleosidase activity

Catalysis of the reaction: a N-D-queuosine + H2O = queuine + D-ribose.


replacement ossification

Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation.


emericellamide biosynthetic process

The chemical reactions and pathways resulting in the formation of emericellamide.


The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria.


negative regulation of mesodermal cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.


Catalysis of the reaction: anhydrotetracycline + H+ + NADPH + O2 = 12-dehydrotetracycline + H2O + NADP+.


positive regulation of presynaptic cytosolic calcium concentration

Any process that increases the concentration of calcium ions in the presynaptic cytosol.


Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2,3-dihydroxyphenyl)-hexa-2,4-dienoate + H2O <=> 2,3-dihydroxybenzoate + 2-oxopent-4-enoate + H+.


oleate 12-hydroxylase activity

Catalysis of the reaction: oleoyl-CoA + NADH + O2 + H+ = ricinoleyl-CoA + NAD + H2O.


auxin influx transmembrane transporter activity

Enables the transfer of auxin, from one side of a membrane to the other, into a cell.


positive regulation of chemotaxis to arachidonic acid

Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid.


proteasome storage granule assembly

The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.


molecular transducer activity

A compound molecular function in which an effector function is controlled by one or more regulatory components.


symbiont-mediated suppression of host tumor necrosis factor-mediated signaling pathway

A process in which a virus interferes with, inhibits or disrupts a tumor necrosis factor-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


TMP biosynthetic process

The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.


anaerobic lactate catabolic process

The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.


adenosyl-fluoride synthase activity

Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.


aminoimidazolase activity

Catalysis of the reaction:4-aminoimidazole + H20 = imidazol-4-one + NH3.


positive regulation of galactotriose transport

Any process that activates or increases the frequency, rate or extent of galactotriose transport.


NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity

Catalysis of the transfer of ADP-ribose groups to the glutamate-2 residue of the N-terminal tail of histone H2B (or an equivalent residue).


monounsaturated fatty acid metabolic process

The chemical reactions and pathways involving monounsaturated fatty acid.


positive regulation of arbuscule formation for nutrient acquisition from host

Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


ammonia monooxygenase activity

Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.


Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2.


gramicidin S biosynthetic process

The chemical reactions and pathways resulting in the formation of gramicidin S.


Catalysis of the reaction: Ser-tRNA(Sec) + ATP = Sep-tRNA(Sec) + ADP.


(+)-sabinol dehydrogenase activity

Catalysis of the reaction: (+)-cis-sabinol + NAD+ = (1S,5S)-sabinone + H+ + NADH.


pyrimidine deoxyribonucleoside metabolic process

The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


extracellular matrix organization involved in endocardium development

A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.


nitrogenous compound fermentation

The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.


protein localization to microvillus membrane

A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.


protein-lipid complex disassembly

The disaggregation of a protein-lipid complex into its constituent components.


sucrose phosphorylase activity

Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.


regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.


chitin-based cuticle sclerotization

The process of hardening of a chitin-based cuticle.


macromolecule deacylation

The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.


viral genome maturation

The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.


glycoside biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.


negative regulation of gluconate transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


regulation of planar cell polarity pathway involved in pericardium morphogenesis

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.


bicyclogermacrene metabolic process

The chemical reactions and pathways involving bicyclogermacrene.


regulation of arginase activity

Any process that modulates the frequency, rate or extent of arginase activity.


disruption of host cell-cell junction

The process by which a symbiont effects a change in the structure or function of an intercellular junction of the host. Intercellular junction include tight junctions and adherens junctions.


cell surface adhesin-mediated gliding motility

Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.


Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.


(1->3),(1->4)-beta-glucan binding

Binding to (1->3),(1->4)-beta-glucan.


21U-RNA metabolic process

The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


Catalysis of the reaction: N-methyl-2-oxoglutaramate + H2O = 2-oxoglutarate + methylammonium.


queuosine biosynthetic process

The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.


quiescent center organization

The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure.


response to host

Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


leucoplast organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.


centromere-nuclear envelope anchor activity

The binding activity of a molecule that brings together the centromeric region of a chromosome and the inner nuclear membrane by interacting with both the centromere/kinetochore complex and the nuclear membrane, in order to establish and maintain the centromere/kinetochore location.


alpha-humulene 10-hydroxylase activity

Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 10-hydroxy-alpha-humulene + NADP + H2O.


bundle of His cell to Purkinje myocyte signaling

Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.


renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure

The physiological response of the kidneys to a decrease in blood flow.


glycerol dehydrogenase [NAD+] activity

Catalysis of the reaction: glycerol + NAD+ = glycerone + H+ + NADH.


positive regulation of filamentous growth of a population of unicellular organisms in response to starvation

Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.


slow muscle cell migration

The orderly movement of a slow muscle cell from one site to another.


oleate hydratase activity

Catalysis of the reaction: (R)-10-hydroxystearate = H2O + oleate.


peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid

The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.


aryl-aldehyde dehydrogenase (NAD) activity

Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+.


negative regulation of retrograde axon cargo transport

Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.


regulation of maltotetraose transport

Any process that modulates the frequency, rate or extent of maltotetraose transport.


Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + caffeoyl-CoA <=> delphinidin 3-O-glucosyl-5-O-caffeoylglucoside + coenzyme A.


negative regulation of zinc ion transmembrane transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.


snRNA methyltransferase activity

Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an snRNA molecule.


negative regulation of single-species biofilm formation

Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.


stigma development

The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.


neuron migration involved in retrograde extension

The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension.


response to amylopectin

A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.


heat acclimation

Any process that increases heat tolerance of an organism in response to high temperatures.


negative regulation of artery smooth muscle contraction

Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction.


positive regulation of macromolecule metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


regulation of growth plate cartilage chondrocyte differentiation

Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.


negative regulation of tongue muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.


apolysis

The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.


regulation of cellotriose transport

Any process that modulates the frequency, rate or extent of cellotriose transport.


orlandin metabolic process

The chemical reactions and pathways involving orlandin.


positive regulation of synaptic vesicle lumen acidification

Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification.


aerobic benzoate metabolic process

The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.


negative regulation of nucleocytoplasmic transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.


gibberellin A12,oxoglutarate:oxygen oxidoreductase activity

Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide.


vestibular receptor cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.


response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.


substrate-independent telencephalic tangential interneuron migration

The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.


xylene metabolic process

The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.


glutamate synthase (ferredoxin) activity

Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.


2,4,6-trinitrotoluene metabolic process

The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.


phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine

The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.


histone H4 acetylation

The modification of histone H4 by the addition of an acetyl group.


light-dependent bacteriochlorophyll biosynthetic process

The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.


Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate.


protein-phosphocysteine-trehalose phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).


apoptotic process involved in tube lumen cavitation

Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.


regulation of (Z)-nonadeca-1,14-diene biosynthetic process

Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.


regulation of secondary shoot formation

Any process that modulates the frequency, rate or extent of secondary shoot formation.


microcin transmembrane transporter activity

Enables the transfer of a microcin from one side of a membrane to the other.


vesicle fusion with Golgi cis cisterna membrane

The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.


anthocyanin accumulation in tissues in response to UV light

The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.


cellodextrin phosphorylase activity

Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.


chemotaxis to cAMP

The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.


pyrroloquinoline quinone biosynthetic process

The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.


Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.


Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP+ = 5alpha-pregnane-3,20-dione + H+ + NADPH.


tryptamine 4-monooxygenase activity

Catalysis of the reaction: tryptamine + reduced acceptor + O2 <=> 4-hydroxytryptamine + acceptor + H2O.


1-indanone dioxygenase activity

Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone.


regulation of cellular defense response

Any process that modulates the frequency, rate or extent of cellular defense response.


regulation of iron ion transmembrane transporter activity

Any process that modulates the frequency, rate or extent of an iron transmembrane transporter activity.


radial glial cell division in pallium

The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.


Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA.


Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.


neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel).


response to reversine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.


G-protein gated monoatomic cation channel activity

A cation channel activity that is gated by binding of a G-protein beta-gamma dimer.


2-nitrophenol 2-monooxygenase activity

Catalysis of the reaction: 2-nitrophenol + 2 H+ + 2 NADPH + O2 = catechol + H2O + 2 NADP+ + nitrite.


regulation of nematode larval development

Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.


high-affinity potassium ion transmembrane transporter activity

Enables the transfer of potassium ions from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


negative regulation of mesodermal cell fate determination

Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.


regulation of mineralocorticoid secretion

Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.


positive regulation of oomycete sporangium development

Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.


regulation of long-day photoperiodism, flowering

Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.


induction of host induced systemic resistance

Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.


1,6-anhydro-N-acetyl-beta-muramic acid metabolic process

The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.


regulation of oocyte development

Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.


hexadecanol dehydrogenase activity

Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH.


4-hydroxytryptamine 4-phosphate methyltransferase activity

Catalysis of the reaction: 2 S-adenosyl-L-methionine (SAM) + 4-hydroxytryptamine 4-phosphate (norbaeocystin) <=> 2 S-adenosyl-L-homocysteine + psilocybin.


purine ribonucleoside metabolic process

The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.


S-succinyltransferase activity

Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.


Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone.


dibenzofuran catabolic process

The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.


negative regulation of optic nerve formation

Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.


alpha-L-rhamnosidase activity

Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.


dihydrouracil oxidase activity

Catalysis of the reaction: 5,6-dihydrouracil + O2 = H2O2 + uracil.


Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.


regulation of salivary gland boundary specification

Any process that modulates the frequency, rate or extent of salivary gland determination.


spinal sensory neuron axon guidance

The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.


septum transversum development

The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.


pigment accumulation in tissues

The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.


mucilage pectin metabolic process

The chemical reactions and pathways involving the pectin component of mucilage.


sitosterol hydroxylase activity

Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP.


auxin mediated signaling pathway involved in phyllotactic patterning

The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.


positive regulation of biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.


glycerate 2-kinase activity

Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP.


gibberellin 12-aldehyde oxidase activity

Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).


Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine.


regulation of action potential firing rate

Any process that regulates the frequency of action potentials in a spike train.


L-cysteine binding

Binding to L-cysteine.


appressorium formation

The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface.


red light photoreceptor activity

The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.


response to papulacandin B

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.


G protein-coupled receptor signaling pathway involved in defense response to Gram-negative bacterium

A G protein-coupled receptor signaling pathway that is involved in the defense response to Gram-negative bacterium.


negative regulation of galactoglucomannan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process.


sulfur oxidation, ferric ion-dependent

A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+).


regulation of stomach fundus smooth muscle contraction

Any process that modulates the frequency, rate or extent of any stomach fundus smooth muscle contraction.


embryo sac morphogenesis

The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.


mucilage metabolic process

The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants.


6G-fructosyltransferase activity

Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).


Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.


Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate.


Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.


Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.


dibenzothiophene monooxygenase activity

Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.


negative regulation of ligase activity

Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.


regulation of fear response

Any process that modulates the frequency, rate or extent of fear response.


regulation of cellular pH reduction

Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell.


dibenzothiophene catabolic process

The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.


anaerobic ethylbenzene metabolic process

The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen.


regulation of response to external stimulus

Any process that modulates the frequency, rate or extent of a response to an external stimulus.


regulation of RNA helicase activity

Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.


IAA-Leu conjugate hydrolase activity

Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.


The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine.


Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.


magnetosome assembly

The aggregation, arrangement and bonding together of a set of components to form a magnetosome. Magnetosomes are specialized organelles for magnetic navigation that comprise membrane-enveloped, nano-sized crystals of a magnetic iron mineral; they are formed by a diverse group of magnetotactic bacteria (MTB).


brainstem precerebellar neuron precursor migration

The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.


regulation of cellular response to gamma radiation

Any process that modulates the frequency, rate or extent of cellular response to gamma radiation.


carpel development

The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.


methylthiotransferase activity

Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.


positive regulation of tryptophan metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.


chemokine (C-X-C motif) ligand 2 production

The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O.


primary adaptive immune response

An adaptive immune response against an antigen not previously encountered by immune system.


2,5-dichlorohydroquinone reductive dehalogenase activity

Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).


pole plasm RNA localization

Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


guanosine tetraphosphate binding

Binding to guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.


subthalamic nucleus development

The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.


lipoteichoic acid D-alanylation

The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA).


prosthetic group metabolic process

The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.


sensory organ precursor cell division

The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron).


Catalysis of the reaction: 1-18:2-2-18:2-sn-glycerol-3-phosphocholine + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.


RITS complex assembly

The aggregation, arrangement and bonding together of a set of components to form a RITS complex.


chloroplast avoidance movement

The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.


locus ceruleus maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.


minus-end directed microtubule sliding

The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.


mannosamine metabolic process

The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.


ascospore wall chitin metabolic process

The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.


capsanthin synthase activity

Catalysis of the reaction: antheraxanthin = capsanthin.


oxidoreductase activity, acting on reduced flavodoxin as donor

Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].


anaerobic glycerol catabolic process

The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.


negative regulation of AMPA receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor activity.


plastid localization

Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.


disruption of cell in another organism

The disruption of a cell of another organism, leading to damage or temporary subversion of that cell.


accessory nerve maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


negative regulation of galactomannan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process.


lignin metabolic process

The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.


The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs.


beta-glucoside kinase activity

Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.


salicylic acid glucosyltransferase (glucoside-forming) activity

Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.


2-hydroxybenzoyl-CoA metabolic process

The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA.


penetration hypha formation

The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.


chloroplast proton-transporting ATP synthase complex assembly

The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.


lens epithelial cell proliferation

The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.


Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane

The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.


precorrin-6Y C5,15-methyltransferase (decarboxylating) activity

Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.


phosphatidate kinase activity

Catalysis of the reaction: ATP + a 1,2-diacyl-sn-glycerol 3-phosphate = ADP + a 1,2-diacyl-sn-glycerol 3-diphosphate.


formation of a compartment boundary

Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.


regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed

A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.


pelvic fin morphogenesis

The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.


negative regulation of metula development

Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.


neuromast hair cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.


4,6-pyruvylated galactose residue metabolic process

The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.


dauer exit

Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development.


positive regulation of leaf senescence

Any process that activates or increases the frequency, rate or extent of leaf senescence.


T-helper 2 cell chemotaxis

The directed movement of a T-helper 2 cell in response to an external stimulus.


citronellyl-CoA dehydrogenase activity

Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+.


regulation of otic vesicle morphogenesis

Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.


pectin metabolic process

The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge.


polyphosphate metabolic process

The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid.


diaminopimelate epimerase activity

Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.


negative regulation of lymphocyte apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.


peptidyl-cystine sulfhydration

The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide.


Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.


interleukin-11 production

The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


pyruvate family amino acid biosynthetic process

The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine.


granulosa cell apoptotic process

Any apoptotic process in a granulosa cell.


regulation of sterol import

Any process that modulates the frequency, rate or extent of sterol import.


negative regulation of viral translation

Any process that stops, prevents or reduces the frequency, rate or extent of viral translation.


acetate catabolic process

The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.


pericyte cell migration

The orderly movement of a pericyte cell from one site to another.


Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.


pollen-style interaction

The interactions (or cell to cell communication) that occur between the male gametophyte (pollen/pollen tube) and the stylar tissues of the female sporophyte.


compound eye retinal cell apoptotic process

Any apoptotic process in a compound eye retinal cell.


cellular response to bacterial lipoprotein

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.


modulation of cell migration in another organism

The process in which an organism effects a change in the process of cell migration in a second organism.


palmatine biosynthetic process

The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants.


pinosylvin synthase activity

Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H+ + 3 malonyl-CoA = 4 CO2 + 4 CoA + pinosylvin.


UAU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UAU codon.


Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.


labrum morphogenesis

The process in which the anatomical structures of labrum are generated and organized.


NADH kinase activity

Catalysis of the reaction: ATP + NADH = ADP + 2 H+ + NADPH.


amylin receptor 1 signaling pathway

The series of molecular signals initiated by an extracellular amylin, or another ligand, combining with an amylin receptor 1 (AMY1), a G protein-coupled receptor complex, on the surface of the target cell. Other ligands that have been shown to initiate the AMY1 signaling pathway include the calcitonin related peptide (CGRP) and adrenomedullin (AM/ADM).


CUU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CUU codon.


latency-replication decision

The process by which a virus switches on its replication cycle in an infected cell.  The process is typically controlled by a genetic swtich controlled by environmental factors such as cell type, cell shape, the availability of nutrients, superinfection or exposure of infected cells to UV or various chemical stimuli.


histone H4R3 arginine deiminase activity

Catalysis of the reaction: H2O + histone H4 L-arginyl (position 3)= histone H4 L-citrullyl (position 3) + NH4+, resulting in histone H4 citrullination at position 3.


oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen.


modification of synaptic structure, modulating synaptic transmission

Any process that modulates synaptic transmission via modification of the structure of the synapse.


fatty-acyl-CoA metabolic process

The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.


galactoglucomannan metabolic process

The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units.


Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.


peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine

The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine.


halogenated hydrocarbon catabolic process

The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, compounds derived from hydrocarbons by replacing one or more hydrogen atoms with halogen atoms.


filamentous growth MAPK cascade

The MAPK cascade which is activated as a result of partial nutrient deprivation and which results in filamentous growth.


Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.


natural killer cell proliferation involved in immune response

The expansion of a natural killer cell population by cell division as part of an immune response.


post-embryonic body morphogenesis

The process in which the anatomical structures of the post-embryonic soma are generated and organized.


gibberellin A28,oxoglutarate:oxygen oxidoreductase activity

Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide.


benzene 1,2-dioxygenase activity

Catalysis of the reaction: benzene + H+ + NADH + O2 = cis-cyclohexa-3,5-diene-1,2-diol + NAD+.


isopropanol dehydrogenase (NADP+) activity

Catalysis of the reaction: NADP+ + propan-2-ol = acetone + H+ + NADPH.


endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs.


ER body organization

A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.


regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation

Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.


negative regulation of T cell tolerance induction

Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction.


regulation of macrophage antigen processing and presentation

Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.


asparagusate reductase activity

Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD+ = asparagusate + H+ + NADH.


peptide stabilization

Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.


single-strand break repair via homologous recombination

The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.


(22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity

Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O.


perturbation of host calcium or calmodulin-mediated signal transduction

A process in which a symbiont alters or subverts a calcium or calmodulin-mediated signal transduction in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of germ tube formation

Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Kdo2-lipid A metabolic process

The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component.


RNA uridine deletion

The modification of an RNA molecule by removal of a uridine nucleotide.


lipoamide metabolic process

The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.


racemase and epimerase activity, acting on hydroxy acids and derivatives

Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule.


6-hydroxy pseudo-oxynicotine monooxygenase activity

Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine.


posterior lateral line neuromast mantle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.


UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-).


pachytene

The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.


sesquarterpene metabolic process

The chemical reactions and pathways involving sesquarterpene.


cellular response to cell-matrix adhesion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.


Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate.


positive regulation of plant organ morphogenesis

Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis.


phosphonopyruvate hydrolase activity

Catalysis of the reaction: 3-phosphonopyruvate + H2O = phosphate + pyruvate.


lipoate transmembrane transporter activity

Enables the transfer of lipoate from one side of a membrane to the other.


lens placode formation

The initial developmental process that will lead to the formation of an eye.


glycuronidase activity

Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.


GTP-dependent polynucleotide 5'-hydroxyl-kinase activity

Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.


regulation of histamine uptake

Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.


catabolite repression

A process in which the presence of one nutrient source leads to a decrease in the frequency, rate, or extent of processes involved in the metabolism of other nutrient sources.


sensory perception of electrical stimulus

The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.


tRNA exon ligation utilizing GTP as source of linkage phosphate

A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process.


inositol heptakisphosphate 4-kinase activity

Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate.


renal filtration cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.


Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA.


sensory organ morphogenesis

Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.


insect visual primordium formation

Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.


Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP.


negative regulation of natural killer cell apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.


envenomation resulting in positive regulation of signal transduction in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism.


rRNA modification guide activity

Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue.


oocyte fate determination

The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.


positive regulation of positive chemotaxis to cAMP

Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon

The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon.


L-homocysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.


Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine.


Catalysis of the reaction: hydroquinone + UDP-D-glucose = H+ + hydroquinone O-beta-D-glucopyranoside + UDP.


pteridine oxidase activity

Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown.


endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.


hemolysis in another organism

The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.


cell wall organization or biogenesis

A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.


NAD(P)H nitroreductase activity

Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.


antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent

The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.


regulation of substrate-dependent cell migration, cell attachment to substrate

Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.


The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.


Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.


regulation of meiotic chromosome separation

Any process that modulates the frequency, rate or extent of meiotic chromosome separation.


suppression by virus of host complement activation

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase.


regulation of cell differentiation involved in phenotypic switching

Any process that modulates the frequency, rate or extent of cell differentiation involved in phenotypic switching.


leucocyanidin oxygenase activity

Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.


chrysobactin transmembrane transporter activity

Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) from one side of a membrane to the other.


positive regulation of cellular response to manganese ion

Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion.


dibenzothiophene dioxygenase activity

Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene.


nicotianamine biosynthetic process

The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.


3-chlorotoluene monooxygenase activity

Catalysis of the reaction: H+ + 3-chlorotoluene + NADH + O2 <=> 3-chlorobenzyl alcohol + NAD + H2O.


Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H2O + H+ = 2,5-dioxopentanoate + NH4.


guanyl nucleotide binding

Binding to a guanyl nucleotide, consisting of guanosine esterified with (ortho)phosphate.