dysferlin isoform h5 (human)

A dysferlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75923-5.


dysferlin isoform h4 (human)

A dysferlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75923-4.


dysferlin isoform h10 (human)

A dysferlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75923-10.


dysferlin isoform h7 (human)

A dysferlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75923-7.


dysferlin isoform h13 (human)

A dysferlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75923-13.


dysferlin isoform h9 (human)

A dysferlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75923-9.


dysferlin isoform h3 (human)

A dysferlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75923-3.


mothers against decapentaplegic homolog 7 isoform h2 (human)

A mothers against decapentaplegic homolog 7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15105-2.


Myc-associated zinc finger protein isoform h3 (human)

A Myc-associated zinc finger protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56270-3.


modulation by symbiont of host salicylic acid-mediated defense response

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process in which a symbiont modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of salicylic acid mediated signaling pathway

Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.


positive regulation of salicylic acid mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction.


positive regulation by symbiont of host salicylic acid-mediated defense response

Any process in which a symbiont activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


symbiont-mediated suppression of defense-related host salicylic acid-mediated signal transduction pathway

A process in which a virus interferes with, inhibits or disrupts a host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.


effector-mediated suppression of host salicylic acid-mediated innate immune signaling

A process mediated by a molecule secreted by a symbiont that results in the suppression of host salicylic acid-mediated innate immune signaling.


testis development-related protein isoform h1 (human)

A testis development-related protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86YL5-1.


testis development-related protein isoform h2 (human)

A testis development-related protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86YL5-2.


PAT complex subunit CCDC47 isoform h2 (human)

A PAT complex subunit CCDC47 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96A33-2.


inactive C-alpha-formylglycine-generating enzyme 2 isoform h4 (human)

An inactive C-alpha-formylglycine-generating enzyme 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NBJ7-4.


inactive C-alpha-formylglycine-generating enzyme 2

A protein that is a translation product of the human SUMF2 gene or a 1:1 ortholog thereof.


inactive C-alpha-formylglycine-generating enzyme 2 isoform h5 (human)

An inactive C-alpha-formylglycine-generating enzyme 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NBJ7-5.


inactive C-alpha-formylglycine-generating enzyme 2 isoform h1 (human)

An inactive C-alpha-formylglycine-generating enzyme 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NBJ7-1.


inactive C-alpha-formylglycine-generating enzyme 2 isoform h3 (human)

An inactive C-alpha-formylglycine-generating enzyme 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NBJ7-3.


inactive C-alpha-formylglycine-generating enzyme 2 isoform h2 (human)

An inactive C-alpha-formylglycine-generating enzyme 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NBJ7-2.


inactive C-alpha-formylglycine-generating enzyme 2, signal peptide removed form (human)

An inactive C-alpha-formylglycine-generating enzyme 2 (human) that has had the signal peptide removed. UniProtKB:Q8NBJ7, 26-301.


peptidyl-histidine autophosphorylation

The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein.


adhesion G protein-coupled receptor A2 isoform h2 (human)

An adhesion G protein-coupled receptor A2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PE1-2.


adhesion G protein-coupled receptor A2

An adhesion G-protein coupled receptor that is a translation product of the human ADGRA2 gene or a 1:1 ortholog thereof.


adhesion G protein-coupled receptor A2 O-glycosylated 2 (human)

An adhesion G protein-coupled receptor A2 (human) that has been O-glycosylated at the residue equivalent to Thr-386 of the amino acid sequence represented by UniProtKB:Q96PE1-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:Q96PE1-1, Thr-386, MOD:00005~GNO:G29068FM.


adhesion G protein-coupled receptor A2 O-glycosylated 3 (human)

An adhesion G protein-coupled receptor A2 (human) that has been O-glycosylated at the residue equivalent to Thr-386 of the amino acid sequence represented by UniProtKB:Q96PE1-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q96PE1-1, Thr-386, MOD:00005~GNO:G43417UB.


adhesion G protein-coupled receptor A2 isoform h1 (human)

An adhesion G protein-coupled receptor A2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PE1-1.


adhesion G protein-coupled receptor A2 O-glycosylated 1 (human)

An adhesion G protein-coupled receptor A2 (human) that has been O-glycosylated at the residue equivalent to Ser-387 of the amino acid sequence represented by UniProtKB:Q96PE1-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q96PE1-1, Ser-387, MOD:00002~GNO:G43417UB.


adhesion G protein-coupled receptor A2 isoform h3 (human)

An adhesion G protein-coupled receptor A2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PE1-3.


nucleotide diphosphokinase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate.


E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 (human)

An E3 ubiquitin-protein ligase pellino homolog 3 isoform 2 that is encoded in the genome of human.


bridging integrator 2 isoform h3 (human)

A bridging integrator 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UBW5-3.


inhibitory extracellular ligand-gated monoatomic ion channel activity

Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels.


Bolwig's organ morphogenesis

The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.


compound eye morphogenesis

The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.


complement factor H N-glycosylated 20 (human)

A complement factor H (human) that has been N-glycosylated at the residue equivalent to Asn-802 of the amino acid sequence represented by UniProtKB:P08603-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P08603-1, Asn-802, MOD:00160~GNO:G42358LZ.


positive regulation of transcription elongation by RNA polymerase I

Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.


CCR4-NOT transcription complex subunit 9 isoform h3 (human)

A CCR4-NOT transcription complex subunit 9 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92600-3.


equilibrative nucleoside transporter 1 isoform h2 (human)

An equilibrative nucleoside transporter 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99808-2.


DNA-directed RNA polymerase III subunit RPC2

A protein that is a translation product of the human POLR3B gene or a 1:1 ortholog thereof.


DNA-directed RNA polymerase III subunit RPC2 isoform h2 (human)

A DNA-directed RNA polymerase III subunit RPC2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NW08-2.


DNA-directed RNA polymerase III subunit RPC2 isoform 1 (human)

A DNA-directed RNA polymerase III subunit RPC2 isoform 1 that is encoded in the genome of human.


methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA R385S (human)

A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Ser residue at the position equivalent to Arg-385 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Arg-385, CHEBI:29999.


methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human)

A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human) that has at least one amino acid residue that differs from the corresponding residue found in another methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human) when such a difference arises as the result of genetic differences, i.e., different alleles of methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human). Operationally, this means the sequence representation of the methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (human) has at least one amino acid residue that differs from the equivalent residue found in the sequence represented by UniProtKB:Q96RQ3-1.


methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA A289V (human)

A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Val residue at the position equivalent to Ala-289 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Ala-289, CHEBI:30015.


methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA L437P (human)

A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that has a Pro residue at the position equivalent to Leu-437 of the amino acid sequence represented by UniProtKB:Q96RQ3. UniProtKB:Q96RQ3, Leu-437, CHEBI:50342.


methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant MCCA D532H (human)

A methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial sequence variant (human) that lacks the region encoded by exon 13 and shifts the reading frame due to the missense mutation D532H altering the splice site at the position equivalent to Asp-532 of the amino acid sequence represented by UniProtKB:Q96RQ3.


histone phosphatase activity

Catalysis of the reaction: a phosphorylated histone + H2O = a protein + phosphate.


histone H2AXS140 phosphatase activity

Catalysis of the reaction: histone H2AX serine phosphate (position 140) + H2O = histone H2AX serine (position 140) + phosphate.


AP-4 complex accessory subunit RUSC1 isoform h2 (human)

An AP-4 complex accessory subunit RUSC1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BVN2-2.


peptidase inhibitor 16 O-glycosylated 12 (human)

A peptidase inhibitor 16 (human) that has been O-glycosylated at the residue equivalent to Thr-285 of the amino acid sequence represented by UniProtKB:Q6UXB8-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q6UXB8-1, Thr-285, MOD:00005~GNO:G58001LT.


ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform h1 (human)

An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13822-1.


ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform h3 (human)

An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13822-3.


IgE B cell receptor complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.


cadherin-12 isoform 1 (human)

A cadherin-12 isoform 1 that is encoded in the genome of human.


NHL-repeat-containing protein 4

A protein that is a translation product of the human NHLRC4 gene or a 1:1 ortholog thereof.


Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication

The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.


kinesin-like protein KIFC3 isoform h4 (human)

A kinesin-like protein KIFC3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BVG8-5.


MacAB-TolC complex

The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.


macrolide transmembrane transporter complex

A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes.


serine/threonine-protein kinase ULK3 isoform 1 (human)

A serine/threonine-protein kinase ULK3 isoform 1 that is encoded in the genome of human.


replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human)

A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form in human. UniProtKB:P27694, 2-616.


replication protein A 70 kDa DNA-binding subunit, initiator methionine removed sumoylated 1 (human)

A replication protein A 70 kDa DNA-binding subunit, initiator methionine removed form (human) that has been post-translationally modified to include sumoylated lysine at positions 449 and 577 of the amino acid sequence represented by UniProtKB:P27694. UniProtKB:P27694, 2-616, Lys-449/Lys-577, MOD:01149.


establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration

Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell.


BTB/POZ domain-containing protein 17 isoform 1 (human)

A BTB/POZ domain-containing protein 17 isoform 1 that is encoded in the genome of human.


filamin-binding LIM protein 1 isoform h2 (human)

A filamin-binding LIM protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8WUP2-2.


protein storage vacuole

A storage vacuole that contains a lytic vacuole; identified in plants.


plant-type vacuole

A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.


central vacuole

A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination.


senescence-associated vacuole

A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.


glycyrrhetinate catabolic process

The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate.


dyslexia-associated protein KIAA0319-like protein O-glycosylated 10 (human)

A dyslexia-associated protein KIAA0319-like protein (human) that has been O-glycosylated at the residue equivalent to Thr-299 of the amino acid sequence represented by UniProtKB:Q8IZA0-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q8IZA0-1, Thr-299, MOD:00005~GNO:G58001LT.


positive regulation of substance P secretion

Any process that activates or increases the frequency, rate or extent of substance P secretion.


positive regulation of substance P secretion, neurotransmission

Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission.


positive regulation of thyroid-stimulating hormone secretion

Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion.


positive regulation of calcitonin secretion

Any process that activates or increases the frequency, rate or extent of calcitonin secretion.


interferon alpha-14

An interferon alpha that is a translation product of the human IFNA14 gene or a 1:1 ortholog thereof.


interferon alpha-14 N-glycosylated 2 (human)

An interferon alpha-14 (human) that has been N-glycosylated at the residue equivalent to Asn-95 of the amino acid sequence represented by UniProtKB:P01570-1, in which the glycan structure is represented by GlyTouCan:G75903TQ. Example: UniProtKB:P01570-1, Asn-95, MOD:00160~GNO:G75903TQ.


interferon alpha-14 N-glycosylated 1 (human)

An interferon alpha-14 (human) that has been N-glycosylated at the residue equivalent to Asn-95 of the amino acid sequence represented by UniProtKB:P01570-1, in which the glycan structure is represented by GlyTouCan:G07392QY. Example: UniProtKB:P01570-1, Asn-95, MOD:00160~GNO:G07392QY.


interferon alpha-14, signal peptide removed form (human)

An interferon alpha-14 (human) that has had the signal peptide removed. UniProtKB:P01570, 24-189.


catenin delta-1 isoform h1ABC (human)

A catenin delta-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60716-1.


CD14 molecule isoform 1 cleaved 2 GPI-anchored form (human)

A CD14 molecule isoform 1 cleaved 2 GPI-anchored form in human. UniProtKB:P08571-1, 20-345, Asn-345, MOD:00167.


platelet endothelial cell adhesion molecule isoform hDelta12 (human)

A platelet endothelial cell adhesion molecule (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16284-2.


3-hydroxyacyl-CoA dehydrogenase type-2 isoform h2 (human)

A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99714-2.


3-hydroxyacyl-CoA dehydrogenase type-2 isoform h1 (human)

A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99714-1.


3-hydroxyacyl-CoA dehydrogenase type-2, initiator methionine removed form (human)

A 3-hydroxyacyl-CoA dehydrogenase type-2 (human) that has had the initiator methionine removed. UniProtKB:Q99714, 2-261.


cAMP-responsive element modulator isoform h11 (human)

A cAMP-responsive element modulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03060-13.


NAD kinase isoform h1 (human)

An NAD kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95544-1.


NAD kinase isoform h2 (human)

An NAD kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O95544-2.


kinesin-like protein KIF15 isoform h2 (human)

A kinesin-like protein KIF15 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NS87-2.


vacuolar protein sorting-associated protein 45 isoform h2 (human)

A vacuolar protein sorting-associated protein 45 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRW7-2.


excitation of vasomotor center by aortic body chemoreceptor signaling

The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.


excitation of vasomotor center by chemoreceptor signaling

The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure.


excitation of vasomotor center by carotid body chemoreceptor signaling

The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.


DNA replication licensing factor MCM4, initiator methionine removed form (human)

A DNA replication licensing factor MCM4 (human) that has had the initiator methionine removed. UniProtKB:P33991, 2-863.


transmembrane protein 18 isoform h1 (human)

A transmembrane protein 18 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96B42-1.


GATOR complex protein WDR59 isoform h4 (human)

A GATOR complex protein WDR59 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PJI9-4.


GATOR complex protein WDR59 isoform h3 (human)

A GATOR complex protein WDR59 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PJI9-3.


GATOR complex protein WDR59 isoform 1 (human)

A GATOR complex protein WDR59 isoform 1 that is encoded in the genome of human.


GATOR complex protein WDR59 isoform h2 (human)

A GATOR complex protein WDR59 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6PJI9-2.


acyl-coenzyme A thioesterase 2, mitochondrial isoform h2 (human)

An acyl-coenzyme A thioesterase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49753-2.


acyl-coenzyme A thioesterase 2, mitochondrial isoform h1 (human)

An acyl-coenzyme A thioesterase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49753-1.


gamma-secretase subunit PEN-2 isoform 1 (human)

A gamma-secretase subunit PEN-2 isoform 1 that is encoded in the genome of human.


transcriptional-regulating factor 1 isoform h5 (human)

A transcriptional-regulating factor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PN7-5.


fibroblast growth factor 16 isoform 1 (human)

A fibroblast growth factor 16 isoform 1 that is encoded in the genome of human.


negative regulation of neurotransmitter uptake

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.


inhibition of histamine uptake

Any process that prevents the activation of the directed movement of histamine into a cell.


inhibition of serotonin uptake

Any process that prevents the activation of the directed movement of serotonin into a cell.


negative regulation of catecholamine uptake involved in synaptic transmission

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.


inhibition of neurotransmitter uptake

Any process that prevents the activation of the directed movement of a neurotransmitter into a cell.


inhibition of norepinephrine uptake

Any process that prevents the activation of the directed movement of norepinephrine into a cell.


negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.


negative regulation of histamine uptake

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.


negative regulation of amino acid uptake involved in synaptic transmission

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.


negative regulation of glutamate uptake involved in transmission of nerve impulse

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.


inhibition of dopamine uptake involved in synaptic transmission

Any process that prevents the activation of the directed movement of dopamine into a cell.


inhibition of acetylcholine uptake

Any process that prevents the activation of the directed movement of acetylcholine into a cell.


catenin alpha-2, initiator methionine removed form (human)

A catenin alpha-2 (human) that has had the initiator methionine removed. UniProtKB:P26232, 2-953.


neutral amino acid uniporter 4 isoform h1 (human)

A neutral amino acid uniporter 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6YBV0-1.


neutral amino acid uniporter 4 isoform h2 (human)

A neutral amino acid uniporter 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6YBV0-2.


cyclic AMP-dependent transcription factor ATF-6 beta isoform h2 (human)

A cyclic AMP-dependent transcription factor ATF-6 beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q99941-1.


negative regulation of eosinophil chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis.


nuclear factor of activated T-cells, cytoplasmic 4 isoform h19 (human)

A nuclear factor of activated T-cells, cytoplasmic 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14934-19.


midchain alkane hydroxylase activity

Catalysis of the conversion of an alkane to a secondary alcohol.


methyltransferase-like protein 25B isoform 1 (human)

A methyltransferase-like protein 25B isoform 1 that is encoded in the genome of human.


methyltransferase-like protein 25B isoform h2 (human)

A methyltransferase-like protein 25B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96FB5-2.


voltage-gated potassium channel subunit beta-2 phosphorylated 1 (human)

A voltage-gated potassium channel subunit beta-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-266 of the amino acid sequence represented by UniProtKB:Q13303-1. Example: UniProtKB:Q13303-1, Ser-266, MOD:00046.


rhomboid-related protein 1 isoform 2 (human)

A rhomboid-related protein 1 isoform 2 that is encoded in the genome of human.


site-specific telomere resolvase activity

Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases.


sperm-egg fusion protein Juno isoform h2 (human)

A sperm-egg fusion protein Juno (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6ND01-2.


sperm-egg fusion protein Juno isoform h1 (human)

A sperm-egg fusion protein Juno (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A6ND01-1.


m-cresol catabolic process

The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.


Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose.


bromodomain-containing protein 8 isoform h4 (human)

A bromodomain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0E9-4.


bromodomain-containing protein 8 isoform h3 (human)

A bromodomain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0E9-3.


bromodomain-containing protein 8 isoform h1 (human)

A bromodomain-containing protein 8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0E9-1.


bromodomain-containing protein 8 isoform 2 (human)

A bromodomain-containing protein 8 isoform 2 that is encoded in the genome of human.


orsellinate decarboxylase activity

Catalysis of the reaction: o-orsellinate + H+ = CO2 + orcinol.


A protein that is a translation product of the human LMOD2 gene or a 1:1 ortholog thereof.


leiomodin-2 isoform h3 (human)

A leiomodin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5Q4-3.


leiomodin-2 isoform h1 (human)

A leiomodin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5Q4-1.


leiomodin-2 isoform h2 (human)

A leiomodin-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6P5Q4-2.


phenylalanine--tRNA ligase alpha subunit isoform h2 (human)

A phenylalanine--tRNA ligase alpha subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y285-2.


luteolin O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H+.


fibronectin type 3 and ankyrin repeat domains protein 1 isoform h3 (human)

A fibronectin type 3 and ankyrin repeat domains protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TC84-3.


prokineticin-1 isoform 1 (human)

A prokineticin-1 isoform 1 that is encoded in the genome of human.


agrin O-glycosylated 19 (human)

An agrin (human) that has been O-glycosylated at the residue equivalent to Thr-162 of the amino acid sequence represented by UniProtKB:O00468-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:O00468-1, Thr-162, MOD:00005~GNO:G29068FM.


tRNA modification GTPase GTPBP3, mitochondrial isoform h3 (human)

A tRNA modification GTPase GTPBP3, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q969Y2-3.


The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA.


fascin-3 isoform 1 (human)

A fascin-3 isoform 1 that is encoded in the genome of human.


E3 ubiquitin-protein ligase RNF170 isoform h2 (human)

An E3 ubiquitin-protein ligase RNF170 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96K19-2.


E3 ubiquitin-protein ligase RNF170 isoform h4 (human)

An E3 ubiquitin-protein ligase RNF170 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96K19-4.


E3 ubiquitin-protein ligase RNF170 isoform h5 (human)

An E3 ubiquitin-protein ligase RNF170 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96K19-5.


E3 ubiquitin-protein ligase RNF170 isoform h1 (human)

An E3 ubiquitin-protein ligase RNF170 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96K19-1.


E3 ubiquitin-protein ligase RNF170 isoform h3 (human)

An E3 ubiquitin-protein ligase RNF170 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96K19-3.


E3 ubiquitin-protein ligase RNF170 isoform h6 (human)

An E3 ubiquitin-protein ligase RNF170 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96K19-6.


cadherin-related family member 1 isoform h2 (human)

A cadherin-related family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96JP9-2.


cadherin-related family member 1 isoform h1 (human)

A cadherin-related family member 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96JP9-1.


erythropoietin N-glycosylated 142 (human)

An erythropoietin (human) that has been N-glycosylated at the residue equivalent to Asn-65 of the amino acid sequence represented by UniProtKB:P01588-1, in which the glycan structure is represented by GlyTouCan:G48109OV. Example: UniProtKB:P01588-1, Asn-65, MOD:00160~GNO:G48109OV.


solute carrier family 46 member 3 isoform h2 (human)

A solute carrier family 46 member 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z3Q1-2.


Catalysis of the reaction: 9,10-epoxy-18-hydroxystearate + H2O <=> 9,10,18-trihydroxystearate.


glucosylglycerate hydrolase activity

Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate.


juvenile hormone epoxide hydrolase activity

Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol.


pyrene-4,5-epoxide hydrolase activity

Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene.


9,10-epoxystearate hydrolase activity

Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate.


phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity

Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene.


phenanthrene-epoxide hydrolase activity

Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene.


mannosylglycerate hydrolase activity

Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate.


Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene.


epoxide hydrolase B activity

Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers.


epoxide hydrolase A activity

Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol.


phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity

Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene.


Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.


limonene-1,2-epoxide hydrolase activity

Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.


aurachin C epoxide hydrolase/isomerase activity

Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P).


trans-epoxysuccinate hydrolase activity

Catalysis of the reaction: trans-2,3-epoxysuccinate + H2O = (2R,3S)-tartrate.


Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene.


isochorismatase activity

Catalysis of the reaction: H2O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.


tetraspanin-16 isoform h2 (human)

A tetraspanin-16 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UKR8-2.


leukosialin O-glycosylated 15 (human)

A leukosialin (human) that has been O-glycosylated at the residue equivalent to Ser-29 of the amino acid sequence represented by UniProtKB:P16150-1, in which the glycan structure is represented by GlyTouCan:G00031MO. Example: UniProtKB:P16150-1, Ser-29, MOD:00002~GNO:G00031MO.


double-stranded RNA-specific adenosine deaminase isoform h2 (human)

A double-stranded RNA-specific adenosine deaminase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55265-2.


double-stranded RNA-specific adenosine deaminase isoform h3 (human)

A double-stranded RNA-specific adenosine deaminase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55265-3.


double-stranded RNA-specific adenosine deaminase isoform 1 (human)

A double-stranded RNA-specific adenosine deaminase isoform 1 that is encoded in the genome of human.


double-stranded RNA-specific adenosine deaminase isoform h4 (human)

A double-stranded RNA-specific adenosine deaminase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55265-4.


double-stranded RNA-specific adenosine deaminase isoform 5 (human)

A double-stranded RNA-specific adenosine deaminase isoform 5 that is encoded in the genome of human.


E3 ubiquitin-protein ligase RNF38 isoform h5 (human)

An E3 ubiquitin-protein ligase RNF38 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H0F5-5.


C2 domain-containing protein 3 isoform h4 (human)

A C2 domain-containing protein 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q4AC94-4.


zinc finger protein 114 isoform h2 (human)

A zinc finger protein 114 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NC26-2.


zinc finger protein 114 isoform h1 (human)

A zinc finger protein 114 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NC26-1.


leukotriene A-4 hydrolase isoform h2 (human)

A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-2.


leukotriene A-4 hydrolase isoform 1 (human)

A leukotriene A-4 hydrolase isoform 1 that is encoded in the genome of human.


leukotriene A-4 hydrolase isoform h3 (human)

A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-3.


leukotriene A-4 hydrolase, initiator methionine removed form (human)

A leukotriene A-4 hydrolase (human) that has had the initiator methionine removed. UniProtKB:P09960, 2-611.


leukotriene A-4 hydrolase isoform h4 (human)

A leukotriene A-4 hydrolase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09960-4.


Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H+.


disulfoglucosamine-6-sulfatase activity

Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H2O = N-sulfo-D-glucosamine + H+ + sulfate.


Ras-associated and pleckstrin homology domains-containing protein 1 isoform hRMO1 (human)

A Ras-associated and pleckstrin homology domains-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q70E73-2.


E3 ubiquitin-protein ligase TRIM68 isoform h2 (human)

An E3 ubiquitin-protein ligase TRIM68 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6AZZ1-2.


E3 ubiquitin-protein ligase TRIM68

A tripartite motif-containing protein that is a translation product of the human TRIM68 gene or a 1:1 ortholog thereof.


E3 ubiquitin-protein ligase TRIM68 isoform h1 (human)

An E3 ubiquitin-protein ligase TRIM68 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6AZZ1-1.


zinc finger protein 211 isoform h6 (human)

A zinc finger protein 211 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13398-6.


aggrecan core protein O-glycosylated 88 (human)

An aggrecan core protein (human) that has been O-glycosylated at the residue equivalent to Thr-2258 of the amino acid sequence represented by UniProtKB:P16112-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P16112-1, Thr-2258, MOD:00005~GNO:G43417UB.


snRNA-activating protein complex subunit 1

A protein that is a translation product of the human SNAPC1 gene or a 1:1 ortholog thereof.


phospholemman isoform 1 (human)

A phospholemman isoform 1 that is encoded in the genome of human.


phospholemman

A protein that is a translation product of the human FXYD1 gene or a 1:1 ortholog thereof.


phospholemman, signal peptide removed form (human)

A phospholemman (human) that has had the signal peptide removed. UniProtKB:O00168, 21-92.


protein delta homolog 1 O-glycosylated 2 (human)

A protein delta homolog 1 (human) that has been O-glycosylated at the residue equivalent to Thr-269 of the amino acid sequence represented by UniProtKB:P80370-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P80370-1, Thr-269, MOD:00005~GNO:G43417UB.


transmembrane protein 254 isoform h2 (human)

A transmembrane protein 254 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TBM7-2.


Rhino-Deadlock-Cutoff Complex

Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation.


positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration

Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.


negative regulation of synaptic vesicle fusion to presynaptic active zone membrane

Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.


positive regulation of mast cell degranulation in another organism

Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism.


induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration

The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission.


regulation of cytotoxic T cell degranulation

Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation.


modulation of mast cell degranulation in another organism

Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.


regulation of natural killer cell degranulation

Any process that modulates the frequency, rate, or extent of natural killer cell degranulation.


regulation of eosinophil degranulation

Any process that modulates the frequency, rate, or extent of eosinophil degranulation.


positive regulation of cytotoxic T cell degranulation

Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.


negative regulation of calcium ion-dependent exocytosis of neurotransmitter

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.


negative regulation of leukocyte degranulation

Any process that stops, prevents, or reduces the rate of leukocyte degranulation.


regulation of exosomal secretion

Any process that modulates the frequency, rate or extent of exosomal secretion.


negative regulation of exocyst assembly

Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.


negative regulation of synaptic vesicle priming

Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.


positive regulation of leukocyte degranulation

Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.


negative regulation of regulated secretory pathway

Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.


regulation of constitutive secretory pathway

Any process that modulates the frequency, rate or extent of constitutive secretory pathway.


negative regulation of basophil degranulation

Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation.


regulation of basophil degranulation

Any process that modulates the frequency, rate or extent of basophil degranulation.


regulation of leukocyte degranulation

Any process that modulates the frequency, rate, or extent of leukocyte degranulation.


positive regulation of basophil degranulation

Any process that activates or increases the frequency, rate or extent of basophil degranulation.


negative regulation of dense core granule exocytosis

Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis.


fibroblast growth factor receptor signaling pathway involved in heart induction

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction.


9-cis-retinoic acid metabolic process

The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative.


kidney smooth muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney.


WD repeat domain phosphoinositide-interacting protein 1 isoform 1 (human)

A WD repeat domain phosphoinositide-interacting protein 1 isoform 1 that is encoded in the genome of human.


integrator complex subunit 10 isoform 1 (human)

An integrator complex subunit 10 isoform 1 that is encoded in the genome of human.


transcription factor Sp1 isoform 1 cleaved 1 (human)

A transcription factor Sp1 isoform 1 cleaved 1 in human. UniProtKB:P08047-1, 65-785.


Y+L amino acid transporter 1

A protein that is a translation product of the human SLC7A7 gene or a 1:1 ortholog thereof.


retinoblastoma-associated protein phosphorylated 1 (human)

A retinoblastoma-associated protein (human) that has been phosphorylated at Ser-612. UniProtKB:P06400, Ser-612, MOD:00046.


olfactory receptor 5D16

A class II olfactory receptor that is a translation product of the human OR5D16 gene or a 1:1 ortholog thereof.


THO complex subunit 4, initiator methionine removed form (human)

A THO complex subunit 4 (human) that has had the initiator methionine removed. UniProtKB:Q86V81, 2-257.


THO complex subunit 4

A protein that is a translation product of the human ALYREF gene or a 1:1 ortholog thereof.


histone H1.1

A histone H1 that is a translation product of the human H1-1 gene or a 1:1 ortholog thereof.


cellular nitrogen compound catabolic process

The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.


cytosine catabolic process

The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.


acrylonitrile catabolic process

The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.


riboflavin catabolic process

The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).


chlorophyll catabolic process

The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.


2-nitropropane catabolic process

The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.


citrulline catabolic process

The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.


cytoplasmic polyadenylation-dependent RNA catabolic process

The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.


cytoplasmic polyadenylation-dependent rRNA catabolic process

The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.


maternal mRNA clearance

The chemical reactions and pathways resulting in the clearance of maternal mRNA transcripts from the zygote as part of the maternal-to-zygote transition in gene expression.


pyrimidine deoxyribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


nuclear mRNA surveillance of mRNP export

The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.


purine-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.


thiamine-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.


pyridine catabolic process

The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.


thiamine catabolic process

The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.


nitrate catabolic process

The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid.


flavin-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.


nucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).


nuclear-transcribed mRNA catabolic process, RNase MRP-dependent

A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends.


antisense RNA transcript catabolic process

The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.


ribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.


pyrimidine ribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.


thiamine diphosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.


nuclear ncRNA surveillance

The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus.


21U-RNA catabolic process

The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.


indole-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.


ncRNA catabolic process

The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).


nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay

The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.


nitrile catabolic process

The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.


coenzyme F420-dependent bicyclic nitroimidazole catabolic process

The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates.


deoxycytidine catabolic process

The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.


RNA fragment catabolic process

The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.


bicyclic nitroimidazole catabolic process

The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole.


pyridine nucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.


aspyridone B catabolic process

The chemical reactions and pathways resulting in the breakdown of aspyridone B.


anaerobic purine nucleobase catabolic process

The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.


atrazine catabolic process to cyanuric acid

The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid.


N-cyclopropylmelamine catabolic process

The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide.


nuclear polyadenylation-dependent ncRNA catabolic process

The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.


folic acid-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives.


pteridine-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.


queuosine catabolic process

The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.


glycine betaine catabolic process

The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.


vitamin B6 catabolic process

The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.


purine deoxyribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


pyrimidine-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.


L-proline betaine catabolic process

The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.


The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.


imidazole-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.


ureide catabolic process

The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium.


2,5-dihydroxypyridine catabolic process to fumarate

The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate.


cyanide catabolic process

The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.


pteridine catabolic process

The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.


heme B catabolic process

The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.


atrazine catabolic process to isopropylamine

The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine.


adenine catabolic process

The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.


aspyridone A catabolic process

The chemical reactions and pathways resulting in the breakdown of aspyridone A.


cyanogenic glycoside catabolic process

The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


bacteriochlorophyll catabolic process

The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.


heme a catabolic process

The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3.


nitroimidazole catabolic process

The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.


corrin catabolic process

The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


siRNA catabolic process

The chemical reactions and pathways resulting in the breakdown of small interfering RNA transcripts (siRNAs).


cytoplasmic RNA surveillance

The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.


nuclear mRNA surveillance of spliceosomal pre-mRNA splicing

The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.


nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts

The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


isoquinoline alkaloid catabolic process

The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.


exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay

The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay.


nitric oxide catabolic process

The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.


carbamoyl phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.


nucleobase-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.


2,5-dihydroxypyridine catabolic process

The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.


carbazole catabolic process

The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.


s-triazine compound catabolic process

The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.


nucleotide-sugar catabolic process

The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.


deoxyuridine catabolic process

The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.


indole phytoalexin catabolic process

The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response.


siroheme catabolic process

The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.


polyadenylation-dependent RNA catabolic process

The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA.


tetrahydrobiopterin catabolic process

The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.


cobalamin catabolic process

The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.


cytidine catabolic process

The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.


nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'

The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.


tetrapyrrole catabolic process

The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.


melatonin catabolic process

The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).


pyridine-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.


atrazine catabolic process

The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide.


cocaine catabolic process

The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.


cyanuric acid catabolic process

The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides.


heme O catabolic process

The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.


UV excision repair protein RAD23 homolog A isoform 1 (human)

A UV excision repair protein RAD23 homolog A isoform 1 that is encoded in the genome of human.


14-3-3 protein beta/alpha isoform Long (human)

A 14-3-3 protein beta/alpha isoform 1 that is encoded in the genome of human.


14-3-3 protein beta/alpha isoform Short (human)

A 14-3-3 protein beta/alpha isoform 2 that is encoded in the genome of human.


probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase isoform h3 (human)

A probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46087-3.


solute carrier family 35 member E3 isoform 1 (human)

A solute carrier family 35 member E3 isoform 1 that is encoded in the genome of human.


pulmonary surfactant-associated protein A1

A protein that is a translation product of the human SFTPA1 gene or a 1:1 ortholog thereof.


pulmonary surfactant-associated protein A1 isoform h2 (human)

A pulmonary surfactant-associated protein A1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWL2-2.


pulmonary surfactant-associated protein A1 isoform h1 (human)

A pulmonary surfactant-associated protein A1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWL2-1.


pulmonary surfactant-associated protein A1, signal peptide removed form (human)

A pulmonary surfactant-associated protein A1 (human) that has had the signal peptide removed. UniProtKB:Q8IWL2, 21-248.


39S ribosomal protein L23, mitochondrial

A protein that is a translation product of the human MRPL23 gene or a 1:1 ortholog thereof.


brevican core protein O-glycosylated 1 (human)

A brevican core protein (human) that has been O-glycosylated at the residue equivalent to Thr-384 of the amino acid sequence represented by UniProtKB:Q96GW7-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q96GW7-1, Thr-384, MOD:00005~GNO:G43417UB.


40S ribosomal protein S13

A protein that is a translation product of the human RPS13 gene or a 1:1 ortholog thereof.


40S ribosomal protein S13, initiator methionine removed form (human)

A 40S ribosomal protein S13 (human) that has had the initiator methionine removed. UniProtKB:P62277, 2-151.


40S ribosomal protein S13 isoform 1 (human)

A 40S ribosomal protein S13 isoform 1 that is encoded in the genome of human.


E3 ubiquitin-protein ligase RNF128 isoform 1 (human)

An E3 ubiquitin-protein ligase RNF128 isoform 1 that is encoded in the genome of human.


nuclear factor 1 X-type

A protein that is a translation product of the human NFIX gene or a 1:1 ortholog thereof.


nuclear factor 1 X-type isoform h1 (human)

A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-1.


nuclear factor 1 X-type isoform h4 (human)

A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-4.


nuclear factor 1 X-type isoform h2 (human)

A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-2.


nuclear factor 1 X-type isoform h5 (human)

A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-5.


nuclear factor 1 X-type isoform 3 (human)

A nuclear factor 1 X-type isoform 3 that is encoded in the genome of human.


nuclear factor 1 X-type isoform h6 (human)

A nuclear factor 1 X-type (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14938-6.


Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H+.


Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3.


Vam6/Vps39-like protein isoform 1 (human)

A Vam6/Vps39-like protein isoform 1 that is encoded in the genome of human.


protein FAM13B isoform h2 (human)

A protein FAM13B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NYF5-2.


tissue-type plasminogen activator N-glycosylated 79 (human)

A tissue-type plasminogen activator (human) that has been N-glycosylated at the residue equivalent to Asn-483 of the amino acid sequence represented by UniProtKB:P00750-1, in which the glycan structure is represented by GlyTouCan:G02000AU. Example: UniProtKB:P00750-1, Asn-483, MOD:00160~GNO:G02000AU.


left anterior basal body

Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage).


FERM domain-containing protein 5

A protein that is a translation product of the human FRMD5 gene or a 1:1 ortholog thereof.


FERM domain-containing protein 5 isoform h1 (human)

A FERM domain-containing protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z6J6-1.


FERM domain-containing protein 5 isoform h2 (human)

A FERM domain-containing protein 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7Z6J6-2.


proline-rich protein 13 isoform h1 (human)

A proline-rich protein 13 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZ81-1.


DNA-directed RNA polymerase I subunit RPA49 isoform h2 (human)

A DNA-directed RNA polymerase I subunit RPA49 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9GZS1-2.


DNA-directed RNA polymerase I subunit RPA49 isoform h1 (human)

A DNA-directed RNA polymerase I subunit RPA49 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9GZS1-1.


cyanelle thylakoid lumen

The volume enclosed by a cyanelle thylakoid membrane.


tyrosine-protein phosphatase non-receptor type 11 phosphorylated 1 (human)

A tyrosine-protein phosphatase non-receptor type 11 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-546 of the amino acid sequence represented by UniProtKB:Q06124. UniProtKB:Q06124, Tyr-546, MOD:00048.


histone H3.1t, initiator methionine removed acetylated 1 (human)

A histone H3.1t (human) that has had the initiator methionine removed and that has been acetylated at the position equivalent to Lys-10 of the amino acid sequence represented by UniProtKB:Q16695. UniProtKB:Q16695, 2-136, Lys-10, MOD:00064.


CUB and zona pellucida-like domain-containing protein 1 isoform h3 (human)

A CUB and zona pellucida-like domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UP6-3.


CUB and zona pellucida-like domain-containing protein 1 isoform h1 (human)

A CUB and zona pellucida-like domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UP6-1.


CUB and zona pellucida-like domain-containing protein 1 isoform h2 (human)

A CUB and zona pellucida-like domain-containing protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q86UP6-2.


ribonucleoprotein PTB-binding 1 isoform h1 (human)

A ribonucleoprotein PTB-binding 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IY67-1.


integrin beta-4 isoform hBeta-4B (human)

An integrin beta-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16144-3.


ER degradation-enhancing alpha-mannosidase-like protein 3, signal peptide removed form (human)

An ER degradation-enhancing alpha-mannosidase-like protein 3 (human) that has had the signal peptide removed. UniProtKB:Q9BZQ6, 42-932.


myelin-associated glycoprotein, signal peptide removed form (human)

A myelin-associated glycoprotein (human) that has had the signal peptide removed. UniProtKB:P20916, 20-626.


myelin-associated glycoprotein

A protein that is a translation product of the human MAG gene or a 1:1 ortholog thereof.


myelin-associated glycoprotein isoform 2 (human)

A myelin-associated glycoprotein isoform 2 that is encoded in the genome of human.


myelin-associated glycoprotein isoform h3 (human)

A myelin-associated glycoprotein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P20916-3.


myelin-associated glycoprotein isoform 1 (human)

A myelin-associated glycoprotein isoform 1 that is encoded in the genome of human.


DnaJ homolog subfamily A member 3, mitochondrial isoform 1 (human)

A DnaJ homolog subfamily A member 3, mitochondrial isoform 1 that is encoded in the genome of human.


triggering receptor expressed on myeloid cells 2 sequence variant A196T (human)

A triggering receptor expressed on myeloid cells 2 sequence variant (human) that has a Thr residue at the position equivalent to Ala-196 of the amino acid sequence represented by UniProtKB:Q9NZC2-1. Example: UniProtKB:Q9NZC2-1, Ala-196, CHEBI:30013.


telomeric repeat-binding factor 1, initiator methionine removed form (human)

A telomeric repeat-binding factor 1, initiator methionine removed form in human. Example: UniProtKB:P54274-1, 2-439.


A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.


cartilage oligomeric matrix protein sequence variant D290N (human)

A cartilage oligomeric matrix protein (human) that has an Asn residue at the position equivalent to Asp-290 of the amino acid sequence represented by UniProtKB:P49747-1. Example: UniProtKB:P49747-1, Asp-290, CHEBI:50347.


tubulin polyglutamylase complex subunit 1

A protein that is a translation product of the human TPGS1 gene or a 1:1 ortholog thereof.


tubulin polyglutamylase complex subunit 1 isoform h1 (human)

A tubulin polyglutamylase complex subunit 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZTW0-1.


tubulin polyglutamylase complex subunit 1 isoform h2 (human)

A tubulin polyglutamylase complex subunit 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZTW0-2.


poly [ADP-ribose] polymerase 2 ADP-ribosylglutamate form (human)

A poly [ADP-ribose] polymerase 2 (human) that includes at least one ADP-ribosylated glutamic acid. UniProtKB:Q9UGN5, MOD:00300.


intercellular adhesion molecule 2 N-glycosylated 3 (human)

An intercellular adhesion molecule 2 (human) that has been N-glycosylated at the residue equivalent to Asn-82 of the amino acid sequence represented by UniProtKB:P13598-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P13598-1, Asn-82, MOD:00160~GNO:G58001LT.


intercellular adhesion molecule 2 N-glycosylated 2 (human)

An intercellular adhesion molecule 2 (human) that has been N-glycosylated at the residue equivalent to Asn-47 of the amino acid sequence represented by UniProtKB:P13598-1, in which the glycan composition is represented by GlyTouCan:G43769HG. Example: UniProtKB:P13598-1, Asn-47, MOD:00160~GNO:G43769HG.


intercellular adhesion molecule 2, signal peptide removed form (human)

An intercellular adhesion molecule 2 (human) that has had the signal peptide removed. UniProtKB:P13598, 25-275.


long-chain-fatty-acid--CoA ligase 6 isoform h7 (human)

A long-chain-fatty-acid--CoA ligase 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UKU0-7.


protein kinase C epsilon type isoform 1 (human)

A protein kinase C epsilon isoform 1 that is encoded in the genome of human.


MHC class Ib protein binding, via lateral surface

Binding to a major histocompatibility complex class Ib molecules via the lateral surface.


TP53-binding protein 1 isoform h2 (human)

A TP53-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12888-2.


hypoxia-inducible factor 3-alpha isoform h3 (human)

A hypoxia-inducible factor 3-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y2N7-3.


Bcl-2-like protein 10

A protein that is a translation product of the human BCL2L10 gene or a 1:1 ortholog thereof.


protein Wnt-2 isoform 1 (human)

A protein Wnt-2 isoform 1 that is encoded in the genome of human.


Ras-related protein Rab-9A, initiator methionine removed form (human)

A Ras-related protein Rab-9A (human) that has had the initiator methionine removed. UniProtKB:P51151, 2-201.


Ras-related protein Rab-9A

A protein that is a translation product of the human RAB9A gene or a 1:1 ortholog thereof.


Ras-related protein Rab-9A isoform 1 (human)

A Ras-related protein Rab-9A isoform 1 that is encoded in the genome of human.


zinc finger protein 765 isoform h1 (human)

A zinc finger protein 765 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7L2R6-1.


zinc finger protein 765 isoform h2 (human)

A zinc finger protein 765 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7L2R6-2.


zinc finger protein 765 isoform h3 (human)

A zinc finger protein 765 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7L2R6-3.


ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform 1 (human)

A ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform 1 that is encoded in the genome of human.


tyrosine-protein kinase Fer

A protein that is a translation product of the human FER gene or a 1:1 ortholog thereof.


tyrosine-protein kinase Fer isoform 1 (human)

A tyrosine-protein kinase Fer (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16591-1.


tyrosine-protein kinase Fer isoform 3 (human)

A tyrosine-protein kinase Fer isoform 3 that is encoded in the genome of human.


tyrosine-protein kinase Fer isoform h2 (human)

A tyrosine-protein kinase Fer (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16591-2.


diamine acetyltransferase 1 isoform 1 (human)

A diamine acetyltransferase 1 isoform 1 that is encoded in the genome of human.


DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 1 (human)

A DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform 1 that is encoded in the genome of human.


aminoglycoside phosphotransferase domain-containing protein 1

A protein that is a translation product of the human HYKK gene or a 1:1 ortholog thereof.


hydroxylysine kinase isoform h2 (human)

A hydroxylysine kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2RU49-2.


hydroxylysine kinase isoform h1 (human)

A hydroxylysine kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2RU49-1.


hydroxylysine kinase isoform h3 (human)

A hydroxylysine kinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2RU49-3.


Kunitz-type protease inhibitor 1 O-glycosylated 2 (human)

A Kunitz-type protease inhibitor 1 (human) that has been O-glycosylated at the residue equivalent to Thr-334 of the amino acid sequence represented by UniProtKB:O43278-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O43278-1, Thr-334, MOD:00005~GNO:G43417UB.


eIF-2-alpha kinase GCN2 isoform h2 (human)

An eIF-2-alpha kinase GCN2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9P2K8-2.