cholecystokinin receptor activity

Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone.


trans-synaptic signaling by endocannabinoid, modulating synaptic transmission

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.


establishment of endothelial blood-brain barrier

Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.


negative regulation of myeloid leukocyte mediated immunity

Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.


prephenate dehydrogenase (NADP+) activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: NADP+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADPH.


head involution

Movement of the anterior ectoderm to the interior of the embryo.


mandelate catabolic process

The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.


regulation of oospore formation

Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.


sequestering of manganese ion

The process of binding or confining manganese ions such that they are separated from other components of a biological system.


positive regulation of intracellular lipid transport

Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.


parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.


spermidine deacetylation

The modification of acetylspermadine by the removal of acetyl groups.


centromere complex assembly

The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.


single-species surface biofilm formation

A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.


butanediol biosynthetic process

The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


positive regulation of activation of membrane attack complex

Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.


regulation of alcohol biosynthetic process

Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.


cellular response to absence of light

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.


neuronal signal transduction

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.


G/U mismatch-specific uracil-DNA glycosylase activity

Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free uracil and leaving an apyrimidinic (AP) site.


N-acetylmannosamine metabolic process

The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.


D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity

Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP.


oligoxyloglucan reducing-end-specific cellobiohydrolase activity

Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.


tagatose kinase activity

Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H+.


trachea morphogenesis

The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.


3',2'-cyclic GMP-AMP binding

Binding to 3',2' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 3',5' and 2',5' linkages.


negative regulation of cystathionine beta-synthase activity

Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity.


negative regulation of skeletal muscle tissue growth

Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.


metanephros development

The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.


endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


microgametogenesis

The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.


pentalenolactone catabolic process

The chemical reactions and pathways resulting in the breakdown of pentalenolactone.


Catalysis of the reaction: cannabigerolate + O2 <=> delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide.


recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex

The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript.


response to lectin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.


regulation of T-helper 17 cell extravasation

Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation.


Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor.


dethiobiotin metabolic process

The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms.


membrane repolarization during AV node cell action potential

The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


positive regulation of G0 to G1 transition

A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.


histone H2A monoubiquitination

The modification of histone H2A by addition of a single ubiquitin group.


glucose-6-phosphate isomerase activity

Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.


Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde.


aureusidin synthase activity

Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.


neuronal action potential back-propagation

Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.


regulation of systemic arterial blood pressure by physical factors

The regulation of blood pressure mediated by detection of forces within the circulatory system.


sporulation resulting in formation of a multicellular or syncytial spore

The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure.


negative regulation of growth

Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.


cell-cell adhesion mediated by cadherin

The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.


facial nucleus development

The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.


sterol homeostasis

Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.


sakuranetin 6-hydroxylase activity

Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP.


positive regulation of octopamine signaling pathway involved in response to food

Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food.


response to chloramphenicol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.


telomere-nuclear envelope anchor activity

The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location.


replication fork reversal

Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.


regulation of apoptotic process involved in outflow tract morphogenesis

Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.


regulation of reproductive process

Any process that modulates the frequency, rate or extent of reproductive process.


calcium oxalate binding

Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).


interneuron axon guidance

The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.


dorsal convergence

The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.


excitation of vasomotor center by baroreceptor signaling

The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.


response to cortisone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.


cell migration involved in kidney development

The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.


negative regulation of MDA-5 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the series of the MDA-5 signaling pathway.


germ cell proliferation

The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.


cellobiose glucosidase activity

Catalysis of the reaction: D-cellobiose + H2O = 2 D-glucose.


protein side chain deglutamylation

The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.


envenomation resulting in modulation of transmission of nerve impulse in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism.


regulation of neutrophil mediated killing of symbiont cell

Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.


receptor recycling

The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.


negative regulation of sensory perception of bitter taste

Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste.


phenylacetaldoxime dehydratase activity

Catalysis of the reaction: (trans)-phenylacetaldoxime = H2O + phenylacetonitrile.


positive regulation of mast cell activation involved in immune response

Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.


Peyer's patch morphogenesis

The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.


O-glycan processing, core 4

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.


anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process

The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.


larval fat body development

The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life.


fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


octopine catabolic process to proline

The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline.


retinal cone cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.


Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H+.


regulation of cardiac muscle cell myoblast differentiation

Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.


creatinase activity

Catalysis of the reaction: creatine + H2O = sarcosine + urea.


choriogonadotropin hormone binding

Binding to choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit.


L-serine metabolic process

The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.


maltose alpha-glucosidase activity

Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose.


molybdenum cofactor guanylyltransferase activity

Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.


imaginal disc-derived wing hair elongation

Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.


beta-acoradiene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid.


proximal convoluted tubule segment 1 cell development

The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.


arabinose isomerase activity

Catalysis of the reaction: D-arabinose = D-ribulose.


NAD-dependent protein decrotonylase activity

Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


ectoine synthase activity

Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H2O.


androgen metabolic process

The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.


neural plate regionalization

The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.


tricaffeoyl spermidine O-methyltransferase activity

Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine.


coronary artery morphogenesis

The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.


trehalose O-mycolyltransferase activity

Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose.


acquisition of nutrients from host

The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.


maintenance of protein location in peroxisome

Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.


intronic snoRNA processing

The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.


negative regulation of ATP:ADP antiporter activity

Any process that stops or reduces the activity of an ATP:ADP antiporter.


glucosamine metabolic process

The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.


non-phosphorylated glucose catabolic process

The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.


seed trichome differentiation

The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.


Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O.


Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + H+ + NADPH.


positive regulation of lateral mesodermal cell fate determination

Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.


response to muscle stretch

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length.


silicate transmembrane transporter activity

Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.


mesodermal to mesenchymal transition involved in gastrulation

The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.


detection of muscle inactivity involved in regulation of muscle adaptation

The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.


aryl-alcohol dehydrogenase (NAD+) activity

Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.


regulation of natural killer cell differentiation involved in immune response

Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.


Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine.


regulation of antigen processing and presentation of peptide antigen via MHC class I

Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.


glycyrrhetinate metabolic process

The chemical reactions and pathways involving glycyrrhetinate.


presynaptic actin cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.


positive regulation of natural killer cell tolerance induction

Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.


conidiogenone biosynthetic process

The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation.


regulation of male pigmentation

Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.


regulation of galactoglucomannan catabolic process

Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.


D-aspartate ligase activity

Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+.


fatty acid primary amide catabolic process

The chemical reactions and pathways resulting in the breakdown of primary fatty amides.


histone dopaminyltransferase activity

Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+).


regulation of toll-like receptor 11 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


somite rostral/caudal axis specification

The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.


regulation of alpha-beta T cell proliferation

Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.


Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP.


ABC-type vitamin B12 transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin.


spore germination

The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).


host cell surface receptor binding

Binding to a receptor on the host cell surface.


cyclopentanol dehydrogenase activity

Catalysis of the reaction: cyclopentanol + NAD+ = cyclopentanone + H+ + NADH.


peptidyl-cysteine modification to S-amindino-L-cysteine

The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.


Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.


NAD+- protein-cysteine ADP-ribosyltransferase activity

Catalysis of the reaction: L-cysteinyl-[protein] + NAD+ = H+ + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein].


protein arginine kinase activity

Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.


benzo(a)pyrene 4,5-dioxygenase activity

Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol.


negative regulation of mitotic cytokinesis

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis.


UAA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UAA codon.


positive regulation of cell migration by vascular endothelial growth factor signaling pathway

The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to its receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.


bulbus arteriosus development

The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.


tetrahydrofolate interconversion

The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.


histone H3Y41 kinase activity

Catalysis of the reaction: histone H3-tyrosine (position 41) + ATP = histone H3-phosphotyrosine (position 41) + ADP. This reaction is the addition of a phosphate group to the tyrosine residue at position 41 of histone H3.


positive regulation of thyroid hormone mediated signaling pathway

Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.


prostaglandin D2 11-ketoreductase activity

Catalysis of the reaction: prostaglandin D2 + H+ + NADPH = 11-epi-prostaglandin F2alpha + NADP+.


response to molecule of fungal origin

Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.


versicolorin B synthase activity

Catalysis of the reaction: versiconal = versicolorin B + H2O.


regulation of cardiac chamber formation

Any process that modulates the frequency, rate or extent of cardiac chamber formation.


Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].


metal-dependent deNEDDylase activity

An metal-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.


dehydroaustinol biosynthetic process

The chemical reactions and pathways resulting in the formation of dehydroaustinol.


stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential

Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.


aldaric acid biosynthetic process

The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.


peripheral B cell selection

Any B cell selection process that occurs in the periphery.


substrate localization to autophagosome

The localization process by which an autophagic substrate is delivered to a forming autophagosome.


dGMP salvage

Any process which produces a dGMP from derivatives of it, without de novo synthesis.


response to methamphetamine hydrochloride

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.


Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate.


pullulan catabolic process

The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.


positive regulation of cytokinesis, site selection

Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis.


formaldehyde dismutase activity

Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.


positive regulation of intracellular sterol transport

Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.


dorsal vessel aortic cell fate commitment

The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.


L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine

The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.


chloroplast fission

The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.


intracellular ornithine homeostasis

A homeostatic process involved in the maintenance of a steady state level of orthinine within a cell.


olfactory bulb development

The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.


lactam catabolic process

The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


notochord regression

The developmental process in which the stucture of the notochord is destroyed in an embryo.


CD80 biosynthetic process

The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.


Lewis x epitope biosynthetic process

The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide.


negative regulation of flocculation

Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.


L-glutamine transmembrane transporter activity

Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.


positive regulation of cholangiocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.


regulation of double fertilization forming a zygote and endosperm

Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.


negative regulation of female pigmentation

Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.


C-terminal protein lipidation

The covalent attachment of a lipid group to the carboxy-terminus of a protein.


cellular response to amino acid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.


lactate 2-monooxygenase activity

Catalysis of the reaction: (S)-lactate + O2 = acetate + CO2 + H2O.


cell wall modification involved in fruit ripening

The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.


regulation of telomerase RNA localization to Cajal body

Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.


positive regulation of acute inflammatory response to antigenic stimulus

Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.


hypoglossal nerve formation

The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


choline transmembrane transporter activity

Enables the transfer of choline from one side of a membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.


positive regulation of stomatal opening

Any process that activates or increases the frequency, rate or extent of stomatal opening.


coenzyme F420-1:gamma-L-glutamate ligase activity

Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate.


amylo-alpha-1,6-glucosidase activity

Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.


acryloyl-CoA reductase (NADH) activity

Catalysis of the reaction: propanoyl-CoA + NAD+ = acryloyl-CoA + H+ + NADH.


glycine dehydrogenase (cyanide-forming) activity

Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.


negative regulation of neuroblast migration

Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.


phagosome-lysosome docking

The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere.


negative regulation of retinoic acid receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.


negative regulation of myeloid progenitor cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.


canthaxanthin 3-hydroxylase activity

Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O.


fat body development

The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.


chromate reductase activity

Catalysis of the reaction: chromate = chromium (III).


pronephros morphogenesis

The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate.


response to cGMP

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.


L-methionine transmembrane transporter activity

Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.


islet amyloid polypeptide processing

The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).


monosaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.


luteolysis

The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.


aldehyde oxygenase (deformylating) activity

Catalysis of the reaction a long-chain aldehyde + O2 + 2 NADPH = an alkane + formate + H2O + 2 NADP+.


negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation

Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis.


negative regulation of eosinophil activation

Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation.


aerobic glycerol catabolic process

The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen.


establishment of floral organ orientation

The process that determines the orientation of the floral organs with reference to the central axis of the flower.


regulation of GABA-A receptor activity

Any process that modulates the frequency, rate or extent of GABA-A receptor activity.


negative regulation of neutrophil apoptotic process

Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.


striated muscle adaptation

Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.


sodium-dependent organic anion transmembrane transporter activity

Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner.


alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity

Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.


glomus development

The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.


Catalysis of the reaction: D-ribose 5-phosphate + ADP + H+ = ADP-ribose + phosphate.


Catalysis of the reaction: dihydrochelirubine + H+ + NADPH + O2 = 12-hydroxydihydrochelirubine + H2O + NADP+.


cadinene catabolic process

The chemical reactions and pathways resulting in the breakdown of cadinene.


mitochondrial DNA replication

The process in which new strands of DNA are synthesized in the mitochondrion.


chemokine (C-C motif) ligand 6 production

The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


response to quercetin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.


positive regulation by symbiont of host apoptotic process

Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.


octanol catabolic process

The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH.


mesenchymal cell proliferation involved in prostate gland development

The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.


response to non-ionic osmotic stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.


regulation of floral organ abscission by signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.


regulation of catalase activity

Any process that modulates the frequency, rate or extent of catalase activity.


asperthecin biosynthetic process

The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.


cellular response to miconazole

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.


trimethylenediamine catabolic process

The chemical reactions and pathways resulting in the breakdown of trimethylenediamine.


serotonin biosynthetic process

The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.


orotic acid metabolic process

The chemical reactions and pathways involving orotic acid.


cortical collecting duct development

The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.


response to acrylamide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.


fumarylpyruvate hydrolase activity

Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.


establishment of planar polarity involved in nephron morphogenesis

Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.


negative regulation of organic acid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


female sex differentiation

The establishment of the sex of a female organism by physical differentiation.


GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine

The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


D-lactate dehydrogenase (cytochrome c-553) activity

Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate.


plastid DNA replication

The process in which new strands of DNA are synthesized in a plastid.


positive regulation of chorionic trophoblast cell proliferation

Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.


L-lyxose metabolic process

The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.


de-etiolation

The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll.


lens fiber cell apoptotic process

Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.


protoporphyrinogen IX biosynthetic process from glycine

The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine.


mannogen catabolic process

The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.


double-stranded RNA adenosine deaminase activity

Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.


lysosomal enzyme production involved in inflammatory response

The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels.


protein homotrimerization

The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.


disruption of host phagocytosis

A process in which in a symbiont interferes with or inhibits host phagocytosis by targeting phagocytic signaling or the cellular phagocytic machinery. The host is defined as the larger of the organisms involved in a symbiotic interaction.


sperm aster formation

Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.


allose metabolic process

The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.


Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate.


terpenoid indole alkaloid biosynthetic process

The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).


GPI anchor release

The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane.


ubiquitin ligase complex scaffold activity

The binding activity of a molecule that brings together an ubiquitin ligase and an ubiquitin ligase-substrate adaptor, permitting those molecules to function in a coordinated way.


regulation of pattern recognition receptor signaling pathway

Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.


voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels

Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.


vesicle targeting, inter-Golgi cisterna

The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.


dendritic cell chemotaxis

The movement of a dendritic cell in response to an external stimulus.


regulation of activated CD4-positive, alpha-beta T cell apoptotic process

Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.


cornea development in camera-type eye

The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.


lipoprotein biosynthetic process via N-acyl transfer

The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex.


protein localization to outer membrane

A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane.


Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O.


thiosulfate binding

Binding to a thiosulfate, a sulfur oxide that has formula O3S2.


phenol O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H+.


cis-chlorobenzene dihydrodiol dehydrogenase activity

Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol.


positive regulation by virus of host cell division

Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division.


pentitol phosphate metabolic process

The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule.


tolerance induction in Peyer's patch

Tolerance induction taking place in the Peyer's patches.


protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan

The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.


cap-independent translational initiation of circular RNA

The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.


positive regulation of male gonad development

Any process that activates or increases the frequency, rate or extent of male gonad development.


pancreas regeneration

The regrowth of a destroyed pancreas.


pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity

Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+.


positive regulation of neutrophil mediated killing of gram-positive bacterium

Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide

The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide.


apposition of dorsal and ventral imaginal disc-derived wing surfaces

The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.


D-arabitol catabolic process

The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.


exocyst assembly

The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.


larval wandering behavior

The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.


regulation of acinar cell proliferation

Any process that modulates the frequency, rate or extent of acinar cell proliferation.


regulation of nematode larval development, heterochronic

Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.


Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine <=> salvigenin + S-adenosyl-L-homocysteine + H+.


regulation of glucose transmembrane transport

Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


negative regulation of compound eye pigmentation

Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.


regulation of microglial cell migration

Any process that modulates the frequency, rate or extent of microglial cell migration.


Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.


biphenyl synthase activity

Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2.


Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate.


protein-N-terminal asparagine amidohydrolase activity

Catalysis of the reaction: N-terminal L-asparaginyl-[protein] + H+ + H2O = N-terminal L-aspartyl-[protein] + NH4+. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein.


pronephros formation

The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


specification of segmental identity, head

The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


regulation of ubiquitin-protein transferase activity

Any process that modulates the frequency, rate or extent of ubiquitin transferase activity.


L-leucine transaminase activity

Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.


mannan synthase activity

Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.


delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity

Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.


protein K33-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.


anterior/posterior axis specification, embryo

The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.


positive regulation of ER to Golgi vesicle-mediated transport

Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.


sequestering of TGFbeta in extracellular matrix

Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins.


regulation of response to butan-1-ol

Any process that modulates the frequency, rate or extent of response to butan-1-ol.


Bergmann glial cell differentiation

The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.


morphogenesis of an epithelial fold

The morphogenetic process in which an epithelial sheet bends along a linear axis.


circumnutation

The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.


cellular response to dithiothreitol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.


positive regulation of signal transduction by p53 class mediator

Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.


metanephric macula densa development

The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.


trans-synaptic signaling by nitric oxide, modulating synaptic transmission

Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.


cell wall macromolecule catabolic process involved in cell wall disassembly

The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.


arachidonic acid epoxygenase activity

Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.


acyl-CoA 11-(E)-desaturase activity

Catalysis of the reaction: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (11E)-delta11-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.


negative regulation of inflammasome-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of an inflammasome-mediated signaling pathway.


UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+.


Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.


mitral valve development

The progression of the mitral valve over time, from its formation to the mature structure.


Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O.


regulation of pancreatic stellate cell proliferation

Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation.


protein localization to mating projection tip

A process in which a protein is transported to, or maintained in, a location within a mating projection tip.


synaptic transmission, noradrenergic

The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.


animal organ regeneration

The regrowth of a lost or destroyed animal organ.


sporocyte differentiation

The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.


arabinonate dehydratase activity

Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H2O.


Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.


Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside.


transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.


autophagosome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.


regulation of defense response by callose deposition

Any process that modulates the frequency, rate or extent of defense response by callose deposition.


Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.


dendritic cell migration

The movement of a dendritic cell within or between different tissues and organs of the body.


Latia-luciferin monooxygenase (demethylating) activity

Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.


guanosine pentaphosphate metabolic process

The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.


cardiac vascular smooth muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.


mycocerosate synthase activity

Catalysis of the reaction: acyl-CoA + 7n H+ + n methylmalonyl-CoA + 2n NADPH = n CO2 + n CoA + n H2O + multi-methyl-branched acyl-CoA + 2n NADP+.


lipoxin metabolic process

The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signaling molecule that has four conjugated double bonds and is derived from arachidonic acid.


positive regulation of embryo sac egg cell differentiation

Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation.


negative regulation of embryo sac egg cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation.


plastid rRNA transcription

The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.


Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.


regulation of neurotransmitter uptake

Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.


cellular response to differentiation-inducing factor 2

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.


protein-glycine ligase activity

Catalysis of the reaction: ATP + glycine + L-glutamyl-[protein] = ADP + glycyl-L-glutamyl-[protein] + H+ + phosphate.


scytalone dehydratase activity

Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H2O.


regulation of cardiac chamber morphogenesis

Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.


histone H2B acetylation

The modification of histone H2B by the addition of an acetyl group.


segment specification

The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.


diethyl 2-methyl-3-oxosuccinate reductase activity

Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ = diethyl 2-methyl-3-oxosuccinate + H+ + NADPH.


negative regulation of response to nutrient levels

Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.


plant-type ovary development

The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.


Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A.


Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-.


fungal-type cell wall disassembly

A cellular process that results in the breakdown of a fungal-type cell wall.


cardiac cell development

The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.


AGU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an AGU codon.


lipid antigen assembly with MHC class Ib protein complex

The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.


regulation of response to oxidative stress

Any process that modulates the frequency, rate or extent of response to oxidative stress.


muscle atrophy

A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.


choline biosynthetic process via phosphoryl-ethanolamine

The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.


alpha-glucan catabolic process

The chemical reactions and pathways resulting in the breakdown of alpha-glucans.


metallodipeptidase activity

Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.


phosphagen biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.


Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal.


androgen binding

Binding to an androgen, a male sex hormone.


bone trabecula morphogenesis

The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.


calcidiol binding

Binding to calcidiol.


regulation of recycling endosome localization within postsynapse

Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.


chlorophyll a biosynthetic process

The chemical reactions and pathways leading to the formation of chlorophyll a.


Catalysis of the reaction: S-adenosyl-L-methionine + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine + 7,4'-dihydroxy, 8-methoxyflavone.


cytoskeleton-nuclear membrane anchor activity

The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane.


endoplasmic reticulum mannose trimming

Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC).


metanephric mesenchyme development

The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.


Catalysis of the reaction: N-formylmethanofuran + A + H2O + H+ = AH(2) + CO2 + methanofuran.


plant epidermis development

The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure.


modulation of nutrient release by host

Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


macula densa development

The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.


septum digestion after cytokinesis

The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.


apical junction assembly

The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.


glycine dehydrogenase (cytochrome) activity

Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c.


T cell inhibitory signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.


mesonephric epithelium development

The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.


sulfide oxidation

The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate.


ecdysteroid catabolic process

The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.


tRNA 5'-end processing

The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.


neuron maturation

A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.


hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity

Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate.


protein-DNA covalent cross-linking via peptidyl-threonine

The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.


protoporphyrinogen oxidase activity

Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.


regulation of amino acid export

Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.


cellular response to fluoxetine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.


ceramide phosphoethanolamine biosynthetic process

The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine.


Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.


arabinose catabolic process

The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.


Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+.


regulation of presynaptic cytosolic calcium ion concentration

Any process that regulates the concentration of calcium in the presynaptic cytosol.


novobiocin biosynthetic process

The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.


positive regulation of mitotic sister chromatid separation

Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.


creatine metabolic process

The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.


Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid.


4-chlorobiphenyl metabolic process

The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.


negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.


negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.


response to histidine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.


cellular response to thyrotropin-releasing hormone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.


alpha2-adrenergic receptor activity

Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein.


G protein-coupled bile acid receptor activity

Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


negative regulation of activated T cell autonomous cell death

Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.


nurse cell nucleus anchoring

Attachment of the nurse cell nucleus to the plasma membrane.


ammonium transmembrane transporter activity

Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.


pronephros structural organization

The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP.


crotonaldehyde redutase activity

Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP.


prostate glandular acinus morphogenesis

The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.


actin crosslink formation

The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.


positive regulation of neurotrophin TRK receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.


inhibitory chemical synaptic transmission

Synaptic transmission that results in an inhibitory postsynaptic potential.


GDP-D-rhamnose biosynthetic process

The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.


Golgi vesicle fusion to target membrane

The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.


Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine.


establishment of protein localization to juxtaparanode region of axon

The directed movement of a protein to the juxtaparanode region of an axon.


response to indole-3-methanol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.


iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide

The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.


endothelial cell activation within high endothelial venule involved in immune response

A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.


colicin transmembrane transporter activity

Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.


Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate.


forebrain dorsal/ventral pattern formation

The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.


negative regulation of endothelial cell chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.


low-affinity basic amino acid transmembrane transporter activity

Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


regulation of cell morphogenesis involved in conjugation with cellular fusion

Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion.


centromere clustering

The process by which centromeres/kinetochores become localized to clusters.


cap mRNA methylation

Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA.


viral extrusion

The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded.


cellular response to manganese ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.


Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol.


regulation of hematopoietic stem cell migration

Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.


geranylgeranyl diphosphate metabolic process

The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.


regulation of development of symbiont in host

Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.


iodophenol O-methyltransferase activity

Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H+.


D-ribose catabolic process

The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).


sulfide dehydrogenase activity

Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S + reduced cytochrome c.


natural killer cell chemotaxis

The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


negative regulation of heart looping

Any process that stops, prevents or reduces the frequency, rate or extent of heart looping.


ABC-type ferric iron transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).


regulation of corticotropin-releasing hormone receptor activity

Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity.


regulation of gastric emptying

Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


positive regulation of phospholipid efflux

Any process that activates or increases the frequency, rate or extent of phospholipid efflux.


propanediol transmembrane transporter activity

Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.


cyclohexanol dehydrogenase activity

Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.


negative regulation of acid-sensing ion channel in another organism

Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism.


cellular response to prostaglandin D stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.


box C/D snoRNP assembly

The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex.


blasticidin S metabolic process

The chemical reactions and pathways involving blasticidin S.


regulation of cell differentiation involved in tissue homeostasis

Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.


maltose transmembrane transporter activity

Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch.


sequoyitol dehydrogenase activity

Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADH.


hydroxyisourate hydrolase activity

Catalysis of the reaction: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+.


monoterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.


brown fat cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.


3-dehydroquinate dehydratase activity

Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H2O.


chemotropism

The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.


cellular response to phosphatidylethanolamine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.


Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.


cell wall pectin metabolic process

The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.


perturbation of host cell cycle progression

A process in which a symbiont interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.


suppression by virus of host NF-kappaB cascade

Any process in which a virus stops, prevents, or reduces a host NF-kappaB cascade.


mitochondrial mRNA processing

Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.


phenylpyruvate decarboxylase activity

Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.


positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.


regulation of metanephric mesenchymal cell migration

Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration.


IgM receptor activity

Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


detection of activity

The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.


(+)-alpha-barbatene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid.


lysobisphosphatidic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.


maintenance of nucleus location

Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.


hydroperoxide metabolic process

The chemical reactions and pathways involving a hydroperoxide.


regulation of platelet rolling

Any process that modulates the frequency, rate or extent of platelet rolling.


Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.


horizontal cell localization

Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.


positive regulation of interleukin-6-mediated signaling pathway

Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.


establishment or maintenance of cell type involved in phenotypic switching

A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.


aerobic respiration, using carbon monoxide as electron donor

The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.


epidermal growth factor receptor signaling pathway involved in lung development

The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.


tetrachloroethylene metabolic process

The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent.


modulation of apoptotic process in another organism

A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism.


Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP.


G protein-coupled ATP receptor activity

Combining with ATP and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


fatty acid amide hydrolase activity

Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.