GPI anchor biosynthetic process

The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.


MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1


RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED


39S RIBOSOMAL PROTEIN L47, MITOCHONDRIAL


E3 UBIQUITIN-PROTEIN LIGASE RFWD3-RELATED


NF-kappaB binding

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.


UBIQUITIN LIGASE PROTEIN PHF9  FANCONI ANEMIA GROUP L PROTEIN


39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL


SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D


SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 2


SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 1


SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D MEMBER 3


TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 3


TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 3


ACYL-COA WAX ALCOHOL ACYLTRANSFERASE 2-RELATED


EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2-RELATED


EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2B


EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 1


EP300-INTERACTING INHIBITOR OF DIFFERENTIATION 2


NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 3


CENTRIOLAR COILED-COIL PROTEIN OF 110 KDA


PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED


SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 2A-RELATED


FAMILY WITH SEQUENCE SIMILARITY 220 MEMBER A


SMALL INTEGRAL MEMBRANE PROTEIN 10-LIKE PROTEIN 1


HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING 5


TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER


TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG


protein N-linked glycosylation via asparagine

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.


ENDOGENOUS RETROVIRUS GROUP S71 MEMBER 1 ENV POLYPROTEIN-RELATED


ENDOGENOUS RETROVIRUS GROUP V MEMBER 1 ENV POLYPROTEIN-RELATED


ENDOGENOUS RETROVIRUS GROUP FC1 ENV POLYPROTEIN-RELATED


ENDOGENOUS RETROVIRUS GROUP 3 MEMBER 1 ENV POLYPROTEIN


ENDOGENOUS RETROVIRAL ENVELOPE PROTEIN HEMO


ENDOGENOUS RETROVIRUS GROUP PABLB MEMBER 1 ENV POLYPROTEIN


ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 12-RELATED


ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 11


ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 8


G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 2


ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 1


G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 3


ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10


G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4


ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 15


G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 1


ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 14


CATION CHANNEL SPERM-ASSOCIATED PROTEIN SUBUNIT DELTA-RELATED


CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT EPSILON


CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT DELTA


sperm principal piece

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.


ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 5


ARMADILLO REPEAT-CONTAINING X-LINKED PROTEIN 4


CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7


CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7


COILED-COIL DOMAIN-CONTAINING PROTEIN 58


PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP11


PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP2


positive regulation of protein ubiquitination

Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.


UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1


GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN


ARSENICAL PUMP-DRIVING ATPASE  ARSENITE-TRANSLOCATING ATPASE


OOCYTE-SECRETED PROTEIN 1 HOMOLOG-RELATED


MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1


MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1


MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA


meiotic sister chromatid cohesion

The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.


GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN


MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED


LYMPHOKINE-ACTIVATED KILLER T-CELL-ORIGINATED PROTEIN KINASE-RELATED


sensory organ morphogenesis

Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.


SERINE_THREONINE-PROTEIN KINASE MRCK GAMMA


SERINE_THREONINE-PROTEIN KINASE MRCK BETA


SERINE_THREONINE-PROTEIN KINASE MRCK ALPHA


BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1


CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 61


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 54


cellular response to abiotic stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.


cellular response to environmental stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus.


cellular response to light stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.


EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN


ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 1


DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE


ADENOSINE DEAMINASE DOMAIN-CONTAINING PROTEIN 2


tRNA-specific adenosine deaminase activity

Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule.


adenosine to inosine editing

The conversion of an adenosine residue to inosine in an RNA molecule by deamination.


APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS


ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 7


ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 3


ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 6


ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 1


ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 5


ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 4


ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN 2


CHORIONIC SOMATOMAMMOTROPIN HORMONE 1-RELATED


DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER


GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1


BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN-LIKE


BRD4-INTERACTING CHROMATIN-REMODELING COMPLEX-ASSOCIATED PROTEIN


CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED


ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3B


ACID SPHINGOMYELINASE-LIKE PHOSPHODIESTERASE 3A


RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE O


TRAF FAMILY MEMBER-ASSOCIATED NF-KAPPA-B ACTIVATOR


LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2


LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 3


LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1


E3 UBIQUITIN-PROTEIN LIGASE HECTD2-RELATED


E3 UBIQUITIN-PROTEIN LIGASE HERC6-RELATED


SECRETION-REGULATING GUANINE NUCLEOTIDE EXCHANGE FACTOR


E3 UBIQUITIN-PROTEIN LIGASE HERC3-RELATED


E3 UBIQUITIN-PROTEIN LIGASE HERC4-RELATED


X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR


FETAL AND ADULT TESTIS-EXPRESSED TRANSCRIPT PROTEIN


MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A52


MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER SLC25A51


CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2


CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2


SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 1


SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 2


SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3


SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 4


TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2


HIGH AFFINITY IMMUNOGLOBULIN ALPHA AND IMMUNOGLOBULIN MU FC RECEPTOR


TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN TMIGD3


ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR


ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2


EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 9


TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN


DELTA AND NOTCH-LIKE EPIDERMAL GROWTH FACTOR-RELATED RECEPTOR


SUSHI, NIDOGEN AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1


NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 4


CASEIN KINASE II SUBUNIT ALPHA PRIME-INTERACTING PROTEIN


CASEIN KINASE II SUBUNIT ALPHA'-INTERACTING PROTEIN


DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4


U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 48 KDA PROTEIN


CILIOGENESIS AND PLANAR POLARITY EFFECTOR 1


MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1_2_3_4_5


cell-substrate junction assembly

The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.


regulation of cell-matrix adhesion

Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.


synaptonemal complex assembly

The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.


male meiotic nuclear division

A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.


ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH4


ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH7


ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH1B


GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45


GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 BETA


GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA


GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEIN GADD45 ALPHA


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A-RELATED


CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2


CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 1


CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE II INHIBITOR 2


PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR


PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR ALPHA-RELATED


U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B


RNA-BINDING PROTEIN WITH MULTIPLE SPLICING


RNA-BINDING PROTEIN WITH MULTIPLE SPLICING 2


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 B


SIMILAR TO DNA SEGMENT, CHR 10, WAYNE STATE UNIVERSITY 102,-EXPRESSED


BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2


BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2-LIKE PROTEIN 2


BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2-LIKE PROTEIN 1


SPLICING FACTOR, ARGININE/SERINE-RICH 19


SPLICING FACTOR, ARGININE_SERINE-RICH 19


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47


BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1  PROTEIN


T-COMPLEX PROTEIN 1 SUBUNIT THETA-LIKE 1-RELATED


chaperonin-containing T-complex

A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.


MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12


MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12-LIKE PROTEIN


C-TYPE LECTIN DOMAIN FAMILY 12 MEMBER A-RELATED


SIMILAR TO CHROMOSOME 3 OPEN READING FRAME 20


TESTIS-SPECIFIC CHROMODOMAIN PROTEIN Y 1-RELATED


ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9


ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9


PUTATIVE GLUTATHIONE HYDROLASE LIGHT CHAIN


GLUTATHIONE HYDROLASE LIGHT CHAIN 2-RELATED


SOMATOMEDIN-B AND THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN


polysome

A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.


TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG


TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 HOMOLOG


SPERMATID-SPECIFIC LINKER HISTONE H1-LIKE PROTEIN-RELATED


TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6


TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6


TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54


RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN


EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 4B


COILED-COIL DOMAIN-CONTAINING PROTEIN 166


COILED-COIL DOMAIN-CONTAINING PROTEIN 121


UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN


cytochrome complex

A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.


mitochondrial respiratory chain complex III

A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.


mitochondrial electron transport, ubiquinol to cytochrome c

The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-B


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM17-A


TIM23 mitochondrial import inner membrane translocase complex

The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.


protein transmembrane transporter activity

Enables the transfer of a protein from one side of a membrane to the other.


protein import into mitochondrial matrix

The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.


PULMONARY SURFACTANT-ASSOCIATED PROTEIN B


CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1


PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29


NADH DEHYDROGENASE  UBIQUINONE  1 ALPHA SUBCOMPLEX SUBUNIT 13


NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13


PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4C-RELATED


PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A-LIKE 4A


PEPTIDYL-PROLYL CIS-TRANS ISOMERASE F, MITOCHONDRIAL


HYDROXYSTEROID (11-BETA) DEHYDROGENASE 1-LIKE B-RELATED


HYDROXYSTEROID 11-BETA-DEHYDROGENASE 1-LIKE PROTEIN


NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 1


NUCLEAR RECEPTOR SUBFAMILY 0 GROUP B MEMBER 2


U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN


SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 1


BETA-CATENIN-LIKE PROTEIN 1  NUCLEAR ASSOCIATED PROTEIN


DOMAIN OF UNKNOWN FUNCTION 71  DUF71 -CONTAINING PROTEIN


tyrosine metabolic process

The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.


regulation of circadian rhythm

Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.


RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL


COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG B, MITOCHONDRIAL


COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG A, MITOCHONDRIAL


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG


ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN


ENDOGENOUS RETROVIRUS GROUP K MEMBER 10 POL PROTEIN-RELATED


IMP metabolic process

The chemical reactions and pathways involving IMP, inosine monophosphate.


SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES


TUBULIN-SPECIFIC CHAPERONE COFACTOR E-LIKE PROTEIN


HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 3


DRESDEN PROSTATE CARCINOMA PROTEIN 2-RELATED


HIGH MOBILITY GROUP NUCLEOSOME-BINDING DOMAIN-CONTAINING PROTEIN 4


PURINOCEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR


F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1XR1


F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1X


F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN TBL1Y


FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 7


AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN


RAS-ASSOCIATED AND PLECKSTRIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1


60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL


TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2


TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED


TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN


CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED


SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21


lipid phosphorylation

The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.


CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE


CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 2


CYTOSOLIC ARGININE SENSOR FOR MTORC1 SUBUNIT 1


ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING


ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN BTBD11


ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 2


E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED


MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 2


MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1


MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 3


CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9B


CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9A


TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN


METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN


MESODERM INDUCTION EARLY RESPONSE PROTEIN 3


MESODERM INDUCTION EARLY RESPONSE PROTEIN 1


MESODERM INDUCTION EARLY RESPONSE PROTEIN 2


EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C


SH3 DOMAIN AND TETRATRICOPEPTIDE REPEATS CONTAINING PROTEIN


SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2


SH3 DOMAIN AND TETRATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1


DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1


GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE  GILT


GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE


SECRETED MODULAR CALCIUM-BINDING PROTEIN


SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 2


SPARC-RELATED MODULAR CALCIUM-BINDING PROTEIN 1


TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4


TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4


SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL


NON-POU DOMAIN-CONTAINING OCTAMER-BINDING PROTEIN


SPLICING FACTOR, PROLINE- AND GLUTAMINE-RICH


HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18


HEAT SHOCK FACTOR-BINDING PROTEIN 1-LIKE PROTEIN 1


PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11


LYSINE-RICH CEACAM1 CO-ISOLATED PROTEIN  LYRIC PROTEIN


MEF2-ACTIVATING MOTIF AND SAP DOMAIN-CONTAINING TRANSCRIPTIONAL REGULATOR


actin filament depolymerization

Disassembly of actin filaments by the removal of actin monomers from a filament.


MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER


39S RIBOSOMAL PROTEIN L39, MITOCHONDRIAL


COILED-COIL DOMAIN-CONTAINING PROTEIN 96


COILED-COIL DOMAIN-CONTAINING PROTEIN 113


AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT ALPHA


AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT GAMMA


AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA


AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT DELTA


VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN


TERATOCARCINOMA-DERIVED GROWTH FACTOR 3-RELATED


KRAB DOMAIN-CONTAINING PROTEIN 5-RELATED


INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN


KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING


KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 2


KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 3


KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 4


KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 1


centriole elongation

The centrosome organization process by which a centriole increases in length as part of the process of replication.


ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74B


CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1


CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 2


VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 4


VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 2


VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 1


VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE 3


RETINOIC ACID INDUCED 1/TRANSCRIPTION FACTOR 20


HOMEOBOX AND LEUCINE ZIPPER PROTEIN HOMEZ


ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 18


ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 12


GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1


EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H


EUKARYOTIC TRANSLATION INITIATION FACTOR 4B


EMBRYONIC POLYADENYLATE-BINDING PROTEIN 2


EUKARYOTIC TRANSLATION INITIATION FACTOR 4H


SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1-LIKE


SYNAPSE DIFFERENTIATION-INDUCING GENE PROTEIN 1


CYTOCHROME C OXIDASE SUBUNIT 7A2, MITOCHONDRIAL


CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL


CYTOCHROME C OXIDASE SUBUNIT 7A3, MITOCHONDRIAL-RELATED


CYTOCHROME C OXIDASE SUBUNIT 7A-RELATED PROTEIN, MITOCHONDRIAL


TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4


TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4B


establishment of mitotic spindle orientation

A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.


THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7B


THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 7A


RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE


RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72


mRNA cleavage and polyadenylation specificity factor complex

A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.


URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14


SET AND MYND DOMAIN-CONTAINING PROTEIN 4


METAL-RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR 2


ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1


MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9


MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9


40S RIBOSOMAL PROTEIN S26-LIKE 1-RELATED


RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED


glycosaminoglycan biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.


aminoglycan biosynthetic process

The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.


CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1


CALCIUM-BINDING AND COILED-COIL DOMAIN-CONTAINING PROTEIN 2


regulation of autophagosome maturation

Any process that modulates the frequency, rate or extent of autophagosome maturation.


SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT


POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA


SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1


SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-3


SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-2


ATPase activator activity

Binds to and increases the activity of an ATP hydrolysis activity.


NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER


PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 6


PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 7


ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1  MULTIPROTEIN BRIDGING FACTOR 1


ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1


UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN


PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 4


PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 2


PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 3


PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 5


PHOSPHOLIPID PHOSPHATASE-RELATED PROTEIN TYPE 1


MITOCHONDRIAL SODIUM_CALCIUM EXCHANGER PROTEIN


nucleotide-excision repair complex

Any complex formed of proteins that act in nucleotide-excision repair.


resolution of meiotic recombination intermediates

The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.


protein localization to ciliary transition zone

A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.


RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN


HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D-LIKE


HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A_B


HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN D0


EXTRACELLULAR MATRIX PHOSPHOGLYCOPROTEIN WITH ASARM MOTIF


GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY


GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4


AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3-RELATED


AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 2


POLYISOPRENOID DIPHOSPHATE_PHOSPHATE PHOSPHOHYDROLASE PLPP6


U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31


SEROLOGICALLY DEFINED COLON CANCER ANTIGEN 8


SARCOPLASMIC RETICULUM HISTIDINE-RICH CALCIUM-BINDING PROTEIN


MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN


MITOCHONDRIAL BROWN FAT UNCOUPLING PROTEIN 1


response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.


CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG


MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER


26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4


26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12


PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3


G-PROTEIN COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A


PAIRED-LIKE HOMEODOMAIN TRANSCRIPTION FACTOR LEUTX


UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 33B


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 24


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16


SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT BETA ISOFORM


SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT


SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT


SERINE_THREONINE-PROTEIN PHOSPHATASE 2A CATALYTIC SUBUNIT ALPHA ISOFORM


GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED


ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1


RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A


RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 3


NEUROEPITHELIAL CELL-TRANSFORMING GENE 1 PROTEIN


COILED-COIL DOMAIN-CONTAINING PROTEIN 88B


RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT


RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA


ear development

The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.


inner ear development

The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.


inner ear morphogenesis

The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.


SOLUTE CARRIER FAMILY 34  SODIUM PHOSPHATE , MEMBER 2-RELATED


SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2C


SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2A


SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B


ribonuclease P complex

A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.


TESTIS-SPECIFIC BASIC PROTEIN Y 1-RELATED


INOSITOL POLYPHOSPHATE-4-PHOSPHATASE TYPE I A


INOSITOL POLYPHOSPHATE 4-PHOSPHATASE TYPE II


pre-replicative complex

A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.


DNA replication preinitiation complex

A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins might include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.


nuclear pre-replicative complex

A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.


PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT ALPHA ISOFORM


PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3


PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM


PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT BETA


PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT ALPHA


PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM


PHOSPHATIDYLINOSITOL 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT GAMMA


PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT BETA ISOFORM


CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL


mitochondrial electron transport, cytochrome c to oxygen

The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.


KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 4


SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE


LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 4


LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 1


LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 6


long-chain fatty acid import into cell

The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.


cardiolipin biosynthetic process

The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.


ALZHEIMER'S DISEASE BETA-AMYLOID RELATED


SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 2


SERINE_THREONINE-PROTEIN PHOSPHATASE WITH EF-HANDS 1


FAMILY WITH SEQUENCE SIMILARITY 153 MEMBER C-RELATED


BACTERICIDAL PERMEABILITY-INCREASING  BPI  PROTEIN-RELATED


60S RIBOSOMAL PROTEIN L37A-LIKE PROTEIN-RELATED


polyamine biosynthetic process

The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.


SPERMATOGENESIS- AND OOGENESIS-SPECIFIC BASIC HELIX-LOOP-HELIX-CONTAINING PROTEIN 2


ZINC TRANSPORTER SLC39A7  HISTIDINE-RICH MEMBRANE PROTEIN KE4


FERM AND PDZ DOMAIN-CONTAINING PROTEIN 2-RELATED


SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL


SERINE PALMITOYLTRANSFERASE SMALL SUBUNIT B


mitotic recombination

The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous DNA region that occurs during mitotic cell cycles.


GTP:AMP PHOSPHOTRANSFERASE AK3, MITOCHONDRIAL


De novo purine biosynthesis

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent


nuclear telomere cap complex

A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome.


chromosome, telomeric region

The end of a linear chromosome, required for the integrity and maintenance of the end. A chromosome telomere usually includes a region of telomerase-encoded repeats the length of which rarely exceeds 20 bp each and that permits the formation of a telomeric loop (T-loop). The telomeric repeat region is usually preceded by a sub-telomeric region that is gene-poor but rich in repetitive elements. Some telomeres only consist of the latter part (for eg. D. melanogaster telomeres).


single-stranded telomeric DNA binding

Binding to single-stranded telomere-associated DNA.


5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 4


5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 3


5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 2


5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1


DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1


CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER


CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3A


CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2A


CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 1


CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 3B


CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER 2B


S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN


GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1


STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1


WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 1


WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 3


WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER 2


SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 1


SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 3


SOLUTE CARRIER FAMILY 52, RIBOFLAVIN TRANSPORTER, MEMBER 2


TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 13 HOMOLOG


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8 A


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM13


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8 B


STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE


STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9


TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3


TFIIS N-TERMINAL DOMAIN-CONTAINING PROTEIN


SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER


SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 1


SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 2


SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3


PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT


PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 6


PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5


NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1


MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG


DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG


DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21-LIKE PROTEIN 1


replication-born double-strand break repair via sister chromatid exchange

The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.


CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 1


CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 2


CUB AND SUSHI DOMAIN-CONTAINING PROTEIN 3


ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD


BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6


2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4


protein hydroxylation

The addition of a hydroxy group to a protein amino acid.


NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 13


NAD(P)H PYROPHOSPHATASE NUDT13, MITOCHONDRIAL


MYOSIN REGULATORY LIGHT CHAIN 2, ATRIAL ISOFORM


MYOSIN REGULATORY LIGHT CHAIN 2, VENTRICULAR_CARDIAC MUSCLE ISOFORM


MYOSIN REGULATORY LIGHT CHAIN 2, SKELETAL MUSCLE ISOFORM


CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2


CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 3


CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 4


CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2


LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN


LETM1 DOMAIN-CONTAINING PROTEIN LETM2, MITOCHONDRIAL


MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN


OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 2


OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 1


COILED-COIL DOMAIN-CONTAINING GLUTAMATE-RICH PROTEIN 1


CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3


motile cilium assembly

The aggregation, arrangement and bonding together of a set of components to form a motile cilium.


PROBABLE MEMBRANE PROTEIN DUF221-RELATED


CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1


INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE-LIKE 2


INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 3


INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1


INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4


RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER


regulation of phospholipase C activity

Any process that modulates the frequency, rate or extent of phospholipase C activity.


activation of phospholipase C activity

The initiation of the activity of the inactive enzyme phospolipase C as the result of The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand.


positive regulation of phospholipase C activity

Any process that increases the rate of phospholipase C activity.


MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1 MINAR1 FAMILY MEMBER


MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1-LIKE


MAJOR INTRINSICALLY DISORDERED NOTCH2-BINDING RECEPTOR 1


ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1


ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2


ARF-GAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 3


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 3


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8B


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 40


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 47


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 42


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 5


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 21


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 18


NACHT DOMAIN- AND WD REPEAT-CONTAINING PROTEIN 1


NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA


PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-INTERACTING PROTEIN 1


U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG


BICD FAMILY-LIKE CARGO ADAPTER 2-RELATED


INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 3 RECEPTOR


RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN


RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 8


RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 9


RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 7


RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 10


ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2


TRANSFORMING GROWTH FACTOR-BETA-INDUCED PROTEIN IG-H3


FAU UBIQUITIN-LIKE AND RIBOSOMAL PROTEIN S30


MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN


39S RIBOSOMAL PROTEIN S30, MITOCHONDRIAL


UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD


positive regulation of extrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.


PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT


CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5


APOPTOSIS FACILITATOR BCL-2-LIKE PROTEIN 14


TESTIS, PROSTATE AND PLACENTA-EXPRESSED PROTEIN


GASTRULATION DEFECTIVE PROTEIN 1-RELATED


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 31


CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 2


CBY1-INTERACTING BAR DOMAIN-CONTAINING PROTEIN 1


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3E


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3G


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3A


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3B


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3F


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3D


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 3C


FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER


FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4


FERM AND PDZ DOMAIN-CONTAINING PROTEIN 1


FERM AND PDZ DOMAIN-CONTAINING PROTEIN 3


MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2


MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B


MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A


DUAL SPECIFICITY PROTEIN PHOSPHATASE 13 ISOFORM B


COILED-COIL DOMAIN-CONTAINING PROTEIN 106


SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1


SYNAPTONEMAL COMPLEX CENTRAL ELEMENT PROTEIN 1-LIKE


NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 2


NK1 TRANSCRIPTION FACTOR-RELATED PROTEIN 1


PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY H MEMBER 3


COILED-COIL DOMAIN-CONTAINING PROTEIN 190


PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP], MITOCHONDRIAL


PHOSPHOENOLPYRUVATE CARBOXYKINASE, CYTOSOLIC [GTP]


UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 3


COILED-COIL DOMAIN-CONTAINING PROTEIN 144A-RELATED


ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1


ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 1A


ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1B


PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED


REPLICATION PROTEIN A 30 KDA SUBUNIT-RELATED


ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 1


ARF-GAP DOMAIN AND FG REPEAT-CONTAINING PROTEIN 2


KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 1


DYNEIN REGULATORY COMPLEX PROTEIN 11-RELATED


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4B


KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2


KATANIN P60 ATPASE-CONTAINING SUBUNIT A1


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A


P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED


WASP HOMOLOG-ASSOCIATED PROTEIN WITH ACTIN, MEMBRANES AND MICROTUBULES


JUNCTION-MEDIATING AND -REGULATORY PROTEIN


TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER


AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1


WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 2


WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 1


MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN


MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN 1


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37B


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37D


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37C


CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 1


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50


CARBOXY-TERMINAL DOMAIN RNA POLYMERASE II POLYPEPTIDE A SMALL PHOSPHATASE 2


bone mineralization

The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.


CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7


CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8


AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN  ARID DOMAIN- CONTAINING PROTEIN   DEAD RINGER PROTEIN   B-CELL REGULATOR OF IGH TRANSCRIPTION   BRIGHT


AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3A


AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3B


AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3C


INTERFERON-INDUCIBLE PROTEIN AIM2 FAMILY MEMBER


PYRIN AND HIN DOMAIN-CONTAINING PROTEIN 1


MYELOID CELL NUCLEAR DIFFERENTIATION ANTIGEN


PLECKSTRIN HOMOLOGY  PH  DOMAIN-CONTAINING PROTEIN


MYOSIN PHOSPHATASE RHO-INTERACTING PROTEIN


FAMILY WITH SEQUENCE SIMILARITY 243 MEMBER A


TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 13


RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1


PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR  PEX5


39S RIBOSOMAL PROTEIN L23, MITOCHONDRIAL


lysine biosynthetic process

The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.


N-ALPHA-ACETYLTRANSFERASE 15, NATA AUXILIARY SUBUNIT


N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT


N-ALPHA-ACETYLTRANSFERASE 16, NATA AUXILIARY SUBUNIT


SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING


SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 2


SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 3


SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1


TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED


SECRETOGLOBIN FAMILY 1C MEMBER 1-RELATED


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 70


RENAL CANCER DIFFERENTIATION GENE 1 PROTEIN


V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 1


HEMATOPOIETIC SH2 DOMAIN-CONTAINING PROTEIN


RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 77


OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL


RNA POLYMERASE II ELONGATION FACTOR ELL2


RNA POLYMERASE II ELONGATION FACTOR ELL3


OCCLUDIN_ELL DOMAIN-CONTAINING PROTEIN 1


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 11


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 5


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 4


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 12


CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 6


MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1


ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 3


NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1


POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1


CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR


NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1


NUCLEAR DISTRIBUTION PROTEIN NUDE-LIKE 1


centrosome localization

Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.


RFAMIDE PEPTIDE GONADOTROPIN INHIBITORY HORMONE


DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1


DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1


DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1


PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47


MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22


FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN


FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 2


FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN 1


COILED-COIL DOMAIN-CONTAINING PROTEIN 186


GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2


GENERAL TRANSCRIPTION FACTOR II-I REPEAT DOMAIN-CONTAINING PROTEIN 2A-RELATED


LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN


LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN


LHFPL TETRASPAN SUBFAMILY MEMBER 6 PROTEIN


LHFPL TETRASPAN SUBFAMILY MEMBER 7 PROTEIN


LHFPL TETRASPAN SUBFAMILY MEMBER 5 PROTEIN


LHFPL TETRASPAN SUBFAMILY MEMBER 1 PROTEIN


LHFPL TETRASPAN SUBFAMILY MEMBER 4 PROTEIN


LHFPL TETRASPAN SUBFAMILY MEMBER 3 PROTEIN


receptor clustering

The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.


DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED


TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES


ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN


ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2  PROTEIN FON -RELATED


ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2


outer kinetochore

The region of a kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.


attachment of mitotic spindle microtubules to kinetochore

The cellular process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex in mitosis.


attachment of spindle microtubules to kinetochore

The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 75B


SOLUBLE SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SSC5D


MACROPHAGE SCAVENGER RECEPTOR TYPES I AND II


SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M130


DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN


SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING GROUP B PROTEIN


SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN SCART1


SCAVENGER RECEPTOR CYSTEINE-RICH TYPE 1 PROTEIN M160


plasma lipoprotein particle clearance

The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME


SMC5-SMC6 COMPLEX LOCALIZATION FACTOR PROTEIN 1


BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED


BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD20


RETINOBLASTOMA-ASSOCIATED PROTEIN  RB -RELATED


heme biosynthetic process

The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.


PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B


RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1


RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1


ribonuclease MRP complex

A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.


nitrate transmembrane transporter activity

Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.


response to osmotic stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 53


INACTIVE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 54


28S RIBOSOMAL PROTEIN S22, MITOCHONDRIAL


mitochondrial small ribosomal subunit

The smaller of the two subunits of a mitochondrial ribosome.


AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1A


AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 1B


CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED


CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 44


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 43


PROTEASE S8 TRIPEPTIDYL PEPTIDASE I  CLN2


NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3


NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 4


NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1


NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 2


cytokine production

The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


calcineurin-mediated signaling

Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression.


TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5


positive regulation of immunoglobulin mediated immune response

Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.


positive regulation of immunoglobulin production

Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.


MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 15


MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 6


MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5


YIP1 INTERACTING FACTOR HOMOLOG  YIF1 PROTEIN


ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2


UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 6.4 KD PROTEIN


ARMC5  ARMADILLO REPEAT-CONTAINING -RELATED


leukocyte cell-cell adhesion

The attachment of a leukocyte to another cell via adhesion molecules.


COILED-COIL DOMAIN-CONTAINING PROTEIN 89


TUMOR SUPPRESSOR CANDIDATE GENE 1 PROTEIN


INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG


INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG


NITROGEN METABOLITE REPRESSION PROTEIN NMRA FAMILY MEMBER


NMRA-LIKE FAMILY DOMAIN-CONTAINING PROTEIN 1


PROTEIN PHOSPHATASE 1-BINDING PROTEIN BIFOCAL


rough endoplasmic reticulum membrane

The lipid bilayer surrounding the rough endoplasmic reticulum.


CYTOCHROME C OXIDASE SUBUNIT 7C, MITOCHONDRIAL


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15A


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B


COILED-COIL DOMAIN-CONTAINING PROTEIN 77


PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65


MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE


SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 1


SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 5


SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 3


SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 6


SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 7


SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4


ATP-DEPENDENT RNA HELICASE DDX60-RELATED


ATP-DEPENDENT RNA HELICASE DDX60-LIKE-RELATED


NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT


NORMAL MUCOSA OF ESOPHAGUS-SPECIFIC GENE 1 PROTEIN


NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 4-LIKE 2


respiratory chain complex IV

A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).


WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 1


CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN


CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT


CAMP-DEPENDENT PROTEIN KINASE TYPE I-BETA REGULATORY SUBUNIT


CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT


CAMP-DEPENDENT PROTEIN KINASE TYPE I-ALPHA REGULATORY SUBUNIT


T-CELL IMMUNOGLOBULIN AND MUCIN DOMAIN-CONTAINING PROTEIN 4


DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A


DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B


PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1


PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 3


PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 1


PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 1


PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2


PROLINE-SERINE-THREONINE PHOSPHATASE-INTERACTING PROTEIN 2


TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B


TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6A


SARCOMA ANTIGEN NY-SAR-24/CYTOSKELETAL PROTEIN SOJO


COILED-COIL DOMAIN-CONTAINING PROTEIN 18


SPINDLE AND CENTRIOLE ASSOCIATED PROTEIN 1 SPICE1


SPINDLE AND CENTRIOLE-ASSOCIATED PROTEIN 1


PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING]


CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 8


CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 5


CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 6


CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 18


CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19


V-TYPE PROTON ATPASE SUBUNIT S1-LIKE PROTEIN


GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL


GLUTAMATE DEHYDROGENASE 2, MITOCHONDRIAL


INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 1-BINDING PROTEIN 1


PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 2


PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT 1


GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN


GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 2


GLUCOCORTICOID MODULATORY ELEMENT-BINDING PROTEIN 1


WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1


MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20


MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG


mitochondrial outer membrane translocase complex

A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.


COILED-COIL DOMAIN-CONTAINING PROTEIN 158


STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 4


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22


protein insertion into mitochondrial inner membrane

The processes mediating the insertion of proteins into the mitochondrial inner membrane. Mitochondrial inner membrane proteins can get inserted from the cytosol, by crossing the outer membrane and being guided by an inner membrane translocase complex into their final destination in the inner membrane. Some proteins present in the intermembrane space can get inserted into the inner mitochondrial membrane. Finally, some proteins are inserted into the inner membrane from the matrix side of the membrane.


NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2


tyrosine phosphorylation of STAT protein

The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.


ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3


A-KINASE ANCHOR PROTEIN 1, MITOCHONDRIAL


SPINDLIN INTERACTOR AND REPRESSOR OF CHROMATIN-BINDING PROTEIN


ZINC FINGER TRANSLOCATION-ASSOCIATED PROTEIN


NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2-RELATED


NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 1


NEURON-SPECIFIC VESICULAR PROTEIN CALCYON


NEURONAL VESICLE TRAFFICKING-ASSOCIATED PROTEIN 2


CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 2


PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER


LOW DENSITY LIPOPROTEIN RECEPTOR ADAPTER PROTEIN 1


CARBOXYL-TERMINAL PDZ LIGAND OF NEURONAL NITRIC OXIDE SYNTHASE PROTEIN


PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1


ALPHA-2,3-SIALYLTRANSFERASE ST3GAL I ISOFORM X1


SECRETORY GRANULE PROTEOGLYCAN CORE PROTEIN


T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED


T-CELL ACTIVATION RHO GTPASE-ACTIVATING PROTEIN


G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP


SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1


CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING


negative regulation of cysteine-type endopeptidase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.


TELOMERASE-BINDING PROTEIN P23  HSP90 CO-CHAPERONE


FAD SYNTHETASE-RELATED  FMN ADENYLYLTRANSFERASE


DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED


FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 20


EUKARYOTIC TRANSLATION INITIATION FACTOR 3  EIF3 -RELATED


EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B


eukaryotic translation initiation factor 3 complex

A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.


HIGH AFFINITY CATIONIC AMINO ACID TRANSPORTER 1


CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1


INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG


MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 3


SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN


SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL


CTF8, CHROMOSOME TRANSMISSION FIDELITY FACTOR 8 HOMOLOG (S. CEREVISIAE)


CHROMOSOME TRANSMISSION FIDELITY PROTEIN 8 HOMOLOG


DECREASED EXPRESSION IN RENAL AND PROSTATE CANCER PROTEIN


CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A


CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-4


CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-3


CYCLIC NUCLEOTIDE-GATED CHANNEL ROD PHOTORECEPTOR SUBUNIT ALPHA


CYCLIC NUCLEOTIDE-GATED CATION CHANNEL BETA-1


CYCLIC NUCLEOTIDE-GATED CATION CHANNEL ALPHA-3


CYCLIC NUCLEOTIDE-GATED OLFACTORY CHANNEL


retina homeostasis

A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.


PROGRAMMED CELL DEATH PROTEIN 11  PRE-RRNA PROCESSING PROTEIN RRP5


COILED-COIL DOMAIN-CONTAINING PROTEIN 184


GOLGI-RESIDENT ADENOSINE 3',5'-BISPHOSPHATE 3'-PHOSPHATASE


inositol phosphate phosphatase activity

Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.


CYTOCHROME C OXIDASE SUBUNIT 8A, MITOCHONDRIAL


CYTOCHROME C OXIDASE SUBUNIT 8C, MITOCHONDRIAL


BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5


BAG FAMILY MOLECULAR CHAPERONE REGULATOR 2


COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL


INOSITOL POLYPHOSPHATE 5-PHOSPHATASE OCRL


TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE


PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE A


TESTICULAR HAPLOID EXPRESSED GENE PROTEIN


TESTICULAR HAPLOID EXPRESSED GENE PROTEIN-LIKE


ACTIN BUNDLING/MISSING IN METASTASIS-RELATED


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 206


ARGININE_SERINE-RICH COILED-COIL PROTEIN 2


STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 14


TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN


TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 6


TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 3


TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5


TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 2


TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 4


TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 1


cellular response to osmotic stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.


TUDOR-INTERACTING REPAIR REGULATOR PROTEIN


ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B


ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13A


KAT8 REGULATORY NSL COMPLEX SUBUNIT 1-LIKE PROTEIN


T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED


T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 2


T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1


CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING


ether hydrolase activity

Catalysis of the hydrolysis of an ether bond, -O-.


A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED


COILED-COIL DOMAIN-CONTAINING PROTEIN 62


CALMODULIN-REGULATED SPECTRIN-ASSOCIATED PROTEIN 1


ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 6


TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN TGN38


TRANS-GOLGI NETWORK INTEGRAL MEMBRANE PROTEIN 2


FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 1


FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 3


FRAS1-RELATED EXTRACELLULAR MATRIX PROTEIN 2


EXTRACELLULAR MATRIX ORGANIZING PROTEIN FRAS1


PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED


SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT ALPHA


SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT BETA


cell killing

Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.


leukocyte mediated cytotoxicity

The directed killing of a target cell by a leukocyte.


MESENTERIC ESTROGEN-DEPENDENT ADIPOGENESIS PROTEIN


DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2


DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA2


DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2


GLYCOSYLTRANSFERASE-LIKE DOMAIN-CONTAINING PROTEIN 1


PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER


INACTIVE GLYCOSYLTRANSFERASE 25 FAMILY MEMBER 3


MULTIFUNCTIONAL PROCOLLAGEN LYSINE HYDROXYLASE AND GLYCOSYLTRANSFERASE LH3


DEXAMETHASONE-INDUCED RAS-RELATED PROTEIN 1


CATION CHANNEL SPERM-ASSOCIATED AUXILIARY SUBUNIT TMEM262


CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 1


CHONDROITIN SULFATE N-ACETYLGALACTOSAMINYLTRANSFERASE 2


RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG


C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4A


C2 CALCIUM-DEPENDENT DOMAIN-CONTAINING PROTEIN 4B


EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN


EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 3


JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE


HEMATOPOIETIC LINEAGE CELL-SPECIFIC PROTEIN-RELATED


protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.


RNA POLYMERASE III  DNA DIRECTED , 39KD SUBUNIT-RELATED


DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6


SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN


X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 5


X-RAY REPAIR CROSS-COMPLEMENTING PROTEIN 6


KILLER CELL LECTIN-LIKE RECEPTOR SUBFAMILY B MEMBER 1


MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED


MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER


MITOCHONDRIAL CARNITINE_ACYLCARNITINE CARRIER PROTEIN


TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL


TRANSCRIPTION TERMINATION FACTOR 1, MITOCHONDRIAL


TRANSCRIPTION TERMINATION FACTOR 2, MITOCHONDRIAL


regulation of lipid catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.


NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1  NFX1


COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER


TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER EDAR


TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 27


TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19


RNA (RNA) POLYMERASE II ASSOCIATED PROTEIN HOMOLOG


MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM34


COILED-COIL DOMAIN-CONTAINING PROTEIN 73


LYSOPHOSPHATIDIC ACID RECEPTOR 5/SPHINGOSYLPHOSPHORYLCHOLINE RECEPTOR


OVARIAN CANCER G-PROTEIN COUPLED RECEPTOR 1


DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED


DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7


ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 15


116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT


30S RIBOSOMAL PROTEIN S2  PROKARYOTIC AND ORGANELLAR


MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR CANDIDATE 2


MICROTUBULE-ASSOCIATED TUMOR SUPPRESSOR 1


COILED-COIL DOMAIN-CONTAINING PROTEIN 69


REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN


REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 3


REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 1


REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 2


NEUROBLAST DIFFERENTIATION-ASSOCIATED PROTEIN AHNAK


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 40


CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 1, MITOCHONDRIAL


CYTOCHROME C OXIDASE SUBUNIT 4 ISOFORM 2, MITOCHONDRIAL


RRNA_TRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN-LIKE PROTEIN 1


PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1


C-TYPE LECTIN DOMAIN FAMILY 17, MEMBER A


LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR


monosaccharide binding

Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.


METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA


GLUCOSE-INDUCED DEGRADATION PROTEIN 4 HOMOLOG


VON WILLEBRAND FACTOR C DOMAIN-CONTAINING PROTEIN 2-LIKE


SOLUTE CARRIER FAMILY 33  ACETYL-COA TRANSPORTER -RELATED


MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 3


CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED


39S RIBOSOMAL PROTEIN L22, MITOCHONDRIAL


PPP2R1A-PPP2R2A-INTERACTING PHOSPHATASE REGULATOR 1


DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL


PYRUVATE DEHYDROGENASE PROTEIN X COMPONENT, MITOCHONDRIAL


ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34


U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10


MYB_SANT DNA-BINDING DOMAIN-CONTAINING 5


SGT1 PROTEIN  HSGT1   SUPPRESSOR OF GCR2


GOLGI REASSEMBLY STACKING PROTEIN  GRASP


ENDOTHELIAL CELL-SPECIFIC MOLECULE 1  ESM-1


ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER


V D J RECOMBINATION-ACTIVATING PROTEIN 2


V(D)J RECOMBINATION-ACTIVATING PROTEIN 2


V(D)J recombination

The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).


somatic cell DNA recombination

Recombination occurring within or between DNA molecules in somatic cells.


somatic diversification of immune receptors via germline recombination within a single locus

The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.


somatic diversification of immune receptors

The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.


FAMILY WITH SEQUENCE SIMILARITY 216 MEMBER A


TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5


TAF5-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 5L


LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 3


TIR DOMAIN-CONTAINING ADAPTER MOLECULE 1


TIR DOMAIN-CONTAINING ADAPTER MOLECULE 2


PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3 FAMILY MEMBER


PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3A


PWWP DOMAIN-CONTAINING DNA REPAIR FACTOR 3B


PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED


TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2


GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN-RELATED


BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 FAMILY MEMBER


BIORIENTATION OF CHROMOSOMES IN CELL DIVISION PROTEIN 1-LIKE 1


ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA


COILED-COIL DOMAIN-CONTAINING PROTEIN 142


CYTOKINE-DEPENDENT HEMATOPOIETIC CELL LINKER


NADH DEHYDROGENASE (UBIQUINONE) 1 BETA SUBCOMPLEX, 4


TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA


DISKS LARGE-ASSOCIATED PROTEIN  DAP   SAP90/PSD-95-ASSOCIATED PROTEIN


PDZ DOMAIN CONTAINING RING FINGER PROTEIN 3, 4


PDZ DOMAIN-CONTAINING RING FINGER PROTEIN 4


MITOCHONDRIAL DYNAMICS PROTEINS 49/51 FAMILY MEMBER


G-PROTEIN COUPLED RECEPTOR 182 AND ESTROGEN RECEPTOR 1


PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT


PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT BETA


PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT GAMMA


PIK3R3 UPSTREAM OPEN READING FRAME PROTEIN


PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT ALPHA


TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2


TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 2


TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 3


TRANSFORMING ACIDIC COILED-COIL-CONTAINING PROTEIN 1


XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 2


XIN ACTIN-BINDING REPEAT-CONTAINING PROTEIN 1


TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN15


KINASE D-INTERACTING SUBSTRATE OF 220 KDA


SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1


DIABLO IAP-BINDING MITOCHONDRIAL PROTEIN


GUANINE NUCLEOTIDE-BINDING PROTEIN BETA  G PROTEIN BETA


GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-1


GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3


GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4


GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5


GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-2


SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A MEMBER 5


GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2-RELATED


SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1


GLOBAL TRANSCRIPTION ACTIVATOR SNF2L1-RELATED


THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17


COILED-COIL DOMAIN-CONTAINING PROTEIN 90B, MITOCHONDRIAL


MITOCHONDRIAL CALCIUM UNIPORTER REGULATOR 1


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 17


ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B3


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1A2


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4A1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 5A1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 6A1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2B1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1B7-RELATED


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 1C1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 2A1


SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 4C1


Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol phosphate + phosphate.


PARKIN COREGULATED GENE PROTEIN  PARK2 COREGULATED


MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED


FELINE LEUKEMIA VIRUS SUBGROUP C RECEPTOR-RELATED PROTEIN 2


FELINE LEUKEMIA VIRUS SUBGROUP C RECEPTOR-RELATED PROTEIN 1


39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL


DIENCEPHALON/MESENCEPHALON HOMEOBOX PROTEIN 1


DIENCEPHALON_MESENCEPHALON HOMEOBOX PROTEIN 1


PLASMINOGEN ACTIVATOR INHIBITOR 1 RNA-BINDING PROTEIN


INTRACELLULAR HYALURONAN-BINDING PROTEIN 4


HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED


HEAT SHOCK TRANSCRIPTION FACTOR, Y-LINKED


HEAT SHOCK TRANSCRIPTION FACTOR, X-LINKED MEMBER 3-RELATED


NUCLEAR RECEPTOR CO-REPRESSOR RELATED  NCOR


U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11


U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED


RAB7A-INTERACTING MON1-CCZ1 COMPLEX SUBUNIT 1


PYRROLINE-5-CARBOXYLATE REDUCTASE 1, MITOCHONDRIAL


NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1


GUANINE NUCLEOTIDE EXCHANGE FACTOR FOR RAB-3A


GRANULE ASSOCIATED RAC AND RHOG EFFECTOR PROTEIN 1


PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 2 PROTEIN


PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE-DEPENDENT RAC EXCHANGER 1 PROTEIN


DEP DOMAIN-CONTAINING MTOR-INTERACTING PROTEIN


COILED-COIL DOMAIN-CONTAINING PROTEIN 154


NH 3 /GLUTAMINE-DEPENDENT NAD +  SYNTHETASE


HAUS complex

A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.


DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED


APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR.


MAM DOMAIN-CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR PROTEIN 1


MAM AND LDL-RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 1


COILED-COIL DOMAIN-CONTAINING PROTEIN 150


STORE-OPERATED CALCIUM ENTRY REGULATOR STIMATE


endoplasmic reticulum tubular network

A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.


cortical endoplasmic reticulum

A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.


regulation of telomere maintenance via telomere lengthening

Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.


BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR


ATP SYNTHASE MEMBRANE SUBUNIT DAPIT, MITOCHONDRIAL


ATP SYNTHASE MEMBRANE SUBUNIT K, MITOCHONDRIAL


SNURPORTIN1  RNUT1 PROTEIN   RNA, U TRANSPORTER 1


protein localization to chromatin

Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.


regulation of chromatin organization

Any process that modulates the frequency, rate or extent of chromatin organization.


PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE HHAT-LIKE PROTEIN


NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15


CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1


CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 2


TRANSCRIPTION INITIATION FACTOR IIH-RELATED


GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1


transcription factor TFIIH core complex

The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.


POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2


POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 2B


SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT


SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A ALPHA ISOFORM


SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 65 KDA REGULATORY SUBUNIT A BETA ISOFORM


SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1


STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED


ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE


ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE


ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, LIVER TYPE


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36


ciliary base

Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 35


DISTAL MEMBRANE-ARM ASSEMBLY COMPLEX PROTEIN 2


LEUCINE-RICH REPEAT-CONTAINING PROTEIN 29


SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3B


SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3A


FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED


ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 44


COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6


INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3-RELATED


INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 3


INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 1


INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 2


INSULIN GROWTH FACTOR-LIKE FAMILY MEMBER 4


AT-HOOK DNA-BINDING MOTIF-CONTAINING PROTEIN 1


GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING


GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN


ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32


ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER C


ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A


ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER E


ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER B


INTERFERON-INDUCIBLE DOUBLE-STRANDED RNA-DEPENDENT PROTEIN KINASE ACTIVATOR A


siRNA processing

A process leading to the generation of a functional small interfering RNA (siRNA). Includes the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides. May also include amplification of the siRNA by RNA-directed RNA polymerase.


MYCOPHENOLIC ACID ACYL-GLUCURONIDE ESTERASE, MITOCHONDRIAL


PALMITOYL-PROTEIN THIOESTERASE ABHD10, MITOCHONDRIAL


TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8


RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER


PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 2


PHOSPHORIBOSYL PYROPHOSPHATE SYNTHASE-ASSOCIATED PROTEIN 1


PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN


DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG


PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 1


PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 3


DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B


DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 7B


MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 8


HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC


CARTILAGE INTERMEDIATE LAYER PROTEIN  CLIP


NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN


SPERMIDINE_SPERMINE N(1)-ACETYLTRANSFERASE-LIKE PROTEIN 1


RETINA AND ANTERIOR NEURAL FOLD HOMEOBOX PROTEIN 2


MORF4 FAMILY-ASSOCIATED PROTEIN 1-RELATED


MORF4 FAMILY-ASSOCIATED PROTEIN 1-LIKE 1


MORF4 FAMILY-ASSOCIATED PROTEIN 1-LIKE PROTEIN UPP-RELATED


DIFFERENTIAL DISPLAY AND ACTIVATED BY P53  DDA3 /G2 S PHASE EXPRESSED 1


PROLINE_SERINE-RICH COILED-COIL PROTEIN 1


TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT


TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA


PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA


post-translational protein targeting to membrane, translocation

The process in which a protein translocates through the ER membrane posttranslationally.


post-translational protein targeting to endoplasmic reticulum membrane

The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.


GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1B-RELATED


GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 3


GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 2


GLYCINE N-ACYLTRANSFERASE-LIKE PROTEIN 1


COILED-COIL DOMAIN-CONTAINING PROTEIN 85B


COILED-COIL DOMAIN-CONTAINING PROTEIN 85A


COILED-COIL DOMAIN-CONTAINING PROTEIN 85C


PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA


CHONDROITIN SULFATE PROTEOGLYCAN 5 -RELATED


PEROXISOME ASSEMBLY PROTEIN 12  PEROXIN-12


LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 2


CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN  BRAIN X-LINKED PROTEIN


CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 1


CYSTEINE-RICH HYDROPHOBIC DOMAIN-CONTAINING PROTEIN 2


NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED


GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG


ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED


COILED-COIL DOMAIN-CONTAINING PROTEIN 84


U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT


U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR 35 KDA SUBUNIT-RELATED PROTEIN 1-RELATED


U2 SMALL NUCLEAR RIBONUCLEOPROTEIN AUXILIARY FACTOR 35 KDA SUBUNIT-RELATED PROTEIN 2


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED


STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1


HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L-LIKE


HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L


GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL


G-PROTEIN COUPLED RECEPTOR 124-LIKE PROTEIN


ACYL-COENZYME A SYNTHETASE ACSM4, MITOCHONDRIAL


ACYL-COENZYME A SYNTHETASE ACSM1, MITOCHONDRIAL


ACYL-COENZYME A SYNTHETASE ACSM6, MITOCHONDRIAL


ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL


ACYL-COENZYME A SYNTHETASE ACSM2B, MITOCHONDRIAL


ACYL-COENZYME A SYNTHETASE ACSM5, MITOCHONDRIAL


ACYL-COENZYME A SYNTHETASE ACSM3, MITOCHONDRIAL


PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 1


PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2-RELATED


EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10


U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG


t-UTP complex

A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.


LUNG CANCER METASTASIS-RELATED  LCMR1  PROTEIN


MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19


SERINE_ARGININE REPETITIVE MATRIX PROTEIN 4-LIKE-RELATED


NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B


developmental pigmentation

The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.


TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3


TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3-LIKE PROTEIN


PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED


PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2


REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT


SINGLE-PASS MEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1


SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT BETA


ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED


PLECKSTRIN DOMAIN-CONTAINING FAMILY G MEMBER 6


PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 6


BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 3


BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE


CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-3


BASIC LEUCINE ZIPPER TRANSCRIPTIONAL FACTOR ATF-LIKE 2


FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 2B


FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 1A


FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 2A


FHF COMPLEX SUBUNIT HOOK INTERACTING PROTEIN 1B


THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED


THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3


MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED


REGENERATING ISLET-DERIVED PROTEIN 3-GAMMA


REGENERATING ISLET-DERIVED PROTEIN 3-ALPHA


peptidoglycan binding

Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.


E3 UBIQUITIN-PROTEIN LIGASE DTX3-RELATED


E3 UBIQUITIN-PROTEIN LIGASE DTX2-RELATED


AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 1


AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2


AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 3


TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A FAMILY MEMBER


TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN A


TRAF-INTERACTING PROTEIN WITH FHA DOMAIN-CONTAINING PROTEIN B


CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 ALPHA


CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-6 BETA


COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17


EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M


FAT STORAGE-INDUCING TRANSMEMBRANE PROTEIN 1


P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN


POLYGLUTAMINE BINDING PROTEIN 1/MARVEL  MEMBRANE-ASSOCIATING  DOMAIN CONTAINING 3


MITOCHONDRIAL PYRUVATE CARRIER 1-LIKE PROTEIN


NMDA RECEPTOR SYNAPTONUCLEAR SIGNALING AND NEURONAL MIGRATION FACTOR


SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED


TESTICULAR SPINDLE-ASSOCIATED PROTEIN SHCBP1L


ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 3


SEMENOGELIN/SEMINAL VESICLE SECRETORY PROTEIN


UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED


GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE  G6PD


GDH_6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN


chromosome separation

The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).


28S RIBOSOMAL PROTEIN S14, MITOCHONDRIAL


CYTOSOLIC CARBOXYPEPTIDASE-LIKE PROTEIN 5


CIRCADIAN LOCOMOTER OUTPUT CYCLES PROTEIN KAPUT


NEURONAL PAS DOMAIN-CONTAINING PROTEIN 2


VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED


VITELLINE MEMBRANE OUTER LAYER PROTEIN 1 HOMOLOG


LIPID DROPLET-REGULATING VLDL ASSEMBLY FACTOR AUP1


PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2


CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER


T-CELL SURFACE GLYCOPROTEIN CD3 ZETA CHAIN


39S RIBOSOMAL PROTEIN L15, MITOCHONDRIAL


MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED


LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL


MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL


ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY


PROTEASE FAMILY M24  METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P


P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1


VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG


GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY-LIKE PROTEIN


GERMINAL CENTER-ASSOCIATED SIGNALING AND MOTILITY PROTEIN


SERINE PROTEASE INHIBITOR KAZAL-TYPE 7 SPINK7


MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER


MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 3


MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 2


MICROTUBULE-ASSOCIATED PROTEIN RP_EB FAMILY MEMBER 1


CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 46


HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1


TELOMERASE RNA COMPONENT INTERACTING RNASE


MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21


RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED


MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1


MOTILE SPERM DOMAIN-CONTAINING PROTEIN 3


TRANSMEMBRANE 4 L6 FAMILY MEMBER 1-RELATED


DNA-DIRECTED RNA POLYMERASES I, II, AND III


DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4


NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1


NUCLEAR FRAGILE X MENTAL RETARDATION-INTERACTING PROTEIN 1


positive regulation of protein secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.


positive regulation of insulin secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.


INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED


TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 6


ACTIVATING TRANSCRIPTION FACTOR  ATF  4/5


CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-4


CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-5


NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 1


NUCLEAR RECEPTOR SUBFAMILY 2 GROUP C MEMBER 2


NUCLEAR RECEPTOR SUBFAMILY 2 GROUP F MEMBER 6


NUCLEAR RECEPTOR SUBFAMILY 2 GROUP E MEMBER 1


ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG


SREBP signaling pathway

The series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.


ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 23


DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4


ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED


TRANSCRIPTION FACTOR CASTOR  PROTEIN MING -RELATED


TUMOR NECROSIS FACTOR RECEPTOR SUBFAMILY MEMBER 4


TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 4


SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 2


SERINE-RICH COILED-COIL DOMAIN-CONTAINING PROTEIN 1


SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 3


CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 2


SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 2


SARCOPLASMIC_ENDOPLASMIC RETICULUM CALCIUM ATPASE 1


CALCIUM-TRANSPORTING ATPASE TYPE 2C MEMBER 1


CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED


DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE


ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL


ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL


ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL


ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11


MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31


core mediator complex

A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.


CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN


STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3


MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1


GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN


52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED


52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE


TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA


morphogenesis of a branching structure

The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.


BILE ACID-COA:AMINO ACID N-ACYLTRANSFERASE


PEROXISOMAL SUCCINYL-COENZYME A THIOESTERASE


MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1


HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER


HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 1 PROTEIN


HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UBIQUITIN-LIKE DOMAIN MEMBER 2 PROTEIN


U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2


PROTEIN LYSINE HYDROXYLATION COMPLEX COMPONENT


SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED


INNER NUCLEAR MEMBRANE PROTEIN MAN1-RELATED


COILED-COIL DOMAIN-CONTAINING PROTEIN 70


LIGAND-DEPENDENT NUCLEAR RECEPTOR-INTERACTING FACTOR 1


CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG


CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL


ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS


TRANSCRIPTION FACTOR OVO-LIKE PROTEIN 3-RELATED


ACETYL-COENZYME A SYNTHETASE, CYTOPLASMIC


ACETYL-COENZYME A SYNTHETASE 2-LIKE, MITOCHONDRIAL


NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL


SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED


STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5


GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1


COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED


COMPLEMENT C1R SUBCOMPONENT-LIKE PROTEIN


COILED-COIL DOMAIN-CONTAINING PROTEIN 74A-RELATED


COILED-COIL DOMAIN-CONTAINING PROTEIN 92


PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4


ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED


ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2


ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 3


PROHEPARIN-BINDING EGF-LIKE GROWTH FACTOR


XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE1


XYLOSYL- AND GLUCURONYLTRANSFERASE LARGE2


protein O-linked mannosylation

The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.


protein mannosylation

The addition of a mannose residue to a protein acceptor molecule.


mannosylation

The covalent attachment of a mannose residue to a substrate molecule.


OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED


MAPK-INTERACTING AND SPINDLE-STABILIZING PROTEIN-LIKE


PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 26


NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B


NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C2-RELATED


39S RIBOSOMAL PROTEIN L16, MITOCHONDRIAL


ATP SYNTHASE SUBUNIT G 2, MITOCHONDRIAL-RELATED