CP2 mannose-ethanolamine phosphotransferase activity

Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.


phylloquinone catabolic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.


NAD+- protein-aspartate ADP-ribosyltransferase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: L-aspartyl-[protein] + NAD+ = 4-O-(ADP-D-ribosyl)-L-aspartyl-[protein] + nicotinamide.


tryptophan 2,3-dioxygenase activity

Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.


regulation of retrograde axon cargo transport

Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.


regulation of substrate adhesion-dependent cell spreading

Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading.


negative regulation of skeletal muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.


isoitalicene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene.


clearance of damaged tissue involved in inflammatory response wound healing

The series of events leading to removal of necrotic debris that contribute to an inflammatory response.


syn-copalyl diphosphate synthase activity

Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.


baroreceptor response to increased systemic arterial blood pressure

The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels.


protein localization to microtubule organizing center

A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.


negative regulation of establishment of T cell polarity

Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.


2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity

Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP.


actin polymerization-dependent cell migration in host

The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of actin at one pole of the symbiont cell. Some bacteria use host actin for migration. The host is defined as the larger of the organisms involved in a symbiotic interaction.


butyryl-CoA dehydrogenase activity

Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein.


circadian sleep/wake cycle

The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.


regulation of polyamine transmembrane transport

Any process that modulates the frequency, rate or extent of polyamine transmembrane transport.


mesonephric connecting tubule development

The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.


Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.


glutamine catabolic process to fumarate, using glutamate synthase (NADPH)

The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13).


epithelial to mesenchymal transition involved in endocardial cushion formation

A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.


L-cysteate sulfo-lyase activity

Catalysis of the reaction: L-cysteate + H2O = NH4 + pyruvate + sulfite.


anaerobic phenol-containing compound metabolic process

The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.


lipoprotein localization to membrane

A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.


propanediol dehydratase activity

Catalysis of the reaction: propane-1,2-diol = H2O + propanal.


oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.


Catalysis of the reaction: dTDP-4-dehydro-2,6-dideoxy-alpha-D-allose + NAD(P) <=> dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate + 2 H+ + NAD(P)H.


violaxanthin oxygenase activity

Catalysis of the reaction: violaxanthin + 2 O2 = 2 5,6-epoxy-3-hydroxy-9-apo-beta-caroten-9-one + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.


transforming growth factor beta1 activation

The release of transforming growth factor beta1 (TGF-beta1) from its latent state.


dATP diphosphatase activity

Catalysis of the reaction: dATP + H2O = dAMP + H+ + diphosphate.


arginine 2-monooxygenase activity

Catalysis of the reaction: L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O.


chitin-based larval cuticle pattern formation

The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.


cellular response to vitamin B1

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.


coenzyme A biosynthetic process

The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.


ribonuclease E activity

Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.


flavonoid glucuronidation

The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor.


arginine decarboxylase activity

Catalysis of the reaction: L-arginine + H+ = agmatine + CO2.


asymmetric Golgi ribbon formation

The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity.


Catalysis of the reaction: 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.


positive regulation of high-density lipoprotein particle clearance

Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


octopamine catabolic process

The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.


response to glucocorticoid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.


GAG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GAG codon.


metanephric nephron tubule morphogenesis

The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.


ABC-type sodium transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na(in) = ADP + phosphate + Na(out).


recognition of apoptotic cell

The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.


protein amidation

Addition of an amide group from a glycine to a protein amino acid.


hercynylcysteine sulfoxide metabolic process

The chemical reactions and pathways involving hercynylcysteine sulfoxide.


somatic diversification of FREP-based immune receptors

The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.


lipo-chitin oligosaccharide transmembrane transporter activity

Enables the transfer of lipo-chitin oligosaccharide from one side of a membrane to the other.


positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation

Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation.


skeletal muscle satellite cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.


[choline trimethylamine-lyase]-activating enzyme activity

Catalyzes the activation of choline trimethylamine-lyase by generation of an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).


ganglion mother cell fate determination

The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed.


disruption by virus of host JAK-STAT cascade via inhibition of host TYK2 activity

Any process in which a virus interferes with a JAK1-STAT signaling cascade in a host organism by reducing the activity of host TYK2 (tyrosine kinase 2). TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits.


cardiac left ventricle morphogenesis

The process in which the left cardiac ventricle is generated and organized.


suppression of blood coagulation in another organism

Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.


negative regulation of ovarian follicle development

Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.


convergent extension involved in nephron morphogenesis

The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.


response to fenofibrate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.


The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.


catechol 2,3-dioxygenase activity

Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.


nitrobenzene 1,2-dioxygenase activity

Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol.


pilus organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.


The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin.


indole-3-acetic acid amido synthetase activity

Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.


viral release via disruption of host peptidoglycan cell wall

The dissemination of mature viral particles from a host cell, caused by a virus hydrolyzing the peptidoglycan cell wall of the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.


SA node cell to atrial cardiac muscle cell communication

The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.


ureidoglycolate dehydrogenase activity

Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+.


cellular response to abscisic acid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.


response to anion stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.


negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.


ascaroside biosynthetic process

The chemical reactions and pathways resulting in the formation of ascaroside.


viral release via pore formation in host cell membrane

The dissemination of mature viral particles from a host cell via the formation by the virus of pores in its host cell membrane.


myo-inositol hexakisphosphate biosynthetic process, lipid-dependent

The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C.


posterior lateral line nerve glial cell morphogenesis involved in differentiation

The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.


lacto-N-biosidase activity

Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.


interleukin-35 production

The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


iron-cytochrome-c reductase activity

Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+.


metamorphosis

A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.


6,7-dihydropteridine reductase activity

Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.


Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+.


Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.


myxococcal fruiting body development

The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.


protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.


plant-type cell wall modification involved in stomatal movement

Any plant-type cell wall modification that is involved in stomatal movement.


anterior/posterior pattern specification involved in kidney development

The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.


hydroquinone 1,2-dioxygenase activity

Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde.


The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


positive regulation of smooth muscle cell chemotaxis

Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.


inulin fructotransferase (DFA-III-forming) activity

Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.


negative regulation of attachment of spindle microtubules to kinetochore

Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.


serotonin receptor signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.


Catalysis of the reaction: a (3R,4R)-4,2'-dihydroxyisoflavan + NADP+ = a (3R)-2'-hydroxyisoflavanone + H+ + NADPH.


ADP-dependent NAD(P)H-hydrate dehydratase activity

Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H+ + NADH + phosphate.


D-xylose transmembrane transporter activity

Enables the transfer of D-xylose from one side of a membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.


oligodendrocyte cell fate specification

The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


positive regulation of cellotriose metabolic process

Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process.


uropod organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.


disruption by symbiont of host cell membrane

The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to granulocyte colony-stimulating factor

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.


negative regulation of urine volume

Any process that decreases the amount of urine excreted from the body over a unit of time.


establishment of thoracic bristle planar orientation

Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.


(1->6)-beta-D-glucan binding

Binding to (1->6)-beta-D-glucan.


neuromuscular process controlling balance

Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.


2-methylcitrate synthase activity

Catalysis of the reaction: H2O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H+.


positive regulation of monocyte antigen processing and presentation

Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.


positive regulation of synaptic metaplasticity

A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor.


positive regulation of hepatocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.


L-cysteine catabolic process to pyruvate

The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate.


Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2.


negative regulation of phospholipase D activity

Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity.


regulation of lymphatic vascular permeability

Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.


carnitinamidase activity

Catalysis of the reaction: (R)-carnitinamide + H2O = (R)-carnitine + NH4.


intracellular borate homeostasis

A homeostatic process involved in the maintenance of a steady state level of tetrahydroxoborate within a cell.


arginine-tRNA ligase activity

Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).


cellular response to papulacandin B

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.


acetaldehyde catabolic process

The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.


negative regulation of chorionic trophoblast cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation.


FAD binding

Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


ventral spinal cord development

The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.


positive regulation of cell fate determination

Any process that activates or increases the frequency, rate or extent of cell fate determination.


Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine.


response to sodium dodecyl sulfate

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.


Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.


ACP-dependent peptidyl-lysine N6-myristoyltransferase activity

Catalysis of the reaction: L-lysyl-[protein] + tetradecanoyl-[ACP] = H+ + holo-[ACP] + N(6)-tetradecanoyl-L-lysyl-[protein].


L-histidine transmembrane transporter activity

Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity

Catalysis of the reaction: L-saccharopine + H2O + NADP+ = L-allysine + L-glutamate + H+ + NADPH.


short-term memory

The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.


L-ascorbic acid metabolic process

The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.


chondrocyte differentiation involved in endochondral bone morphogenesis

The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.


endosperm development

The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.


galacturonate transmembrane transporter activity

Enables the transfer of galacturonate from one side of a membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.


establishment of pigment granule localization

The directed movement of a pigment granule to a specific location.


Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate.


jasmonoyl-valine synthetase activity

Catalysis of the reaction: L-valine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine.


Catalysis of the reaction: ATP + UDP-N-acetyl-alpha-D-muramate + L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate.


regulation of astrocyte activation

Any process that modulates the frequency, rate or extent of astrocyte activation.


adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway

An adenylate cyclase-activating G protein-coupled receptor signaling pathway initiated by glucose binding to its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process.


positive regulation of post-embryonic development

Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.


delta12-fatty-acid desaturase activity

Catalysis of the reaction: oleoyl-CoA + O2 + a reduced electron acceptor <=> linoleoyl-CoA + 2 H2O + an oxidized electron acceptor. This microsomal enzyme introduces a cis double bond at position 12 of fatty-acyl-CoAs that contain a cis double bond at position 9.


CoA pyrophosphatase activity

Catalysis of the reaction: coenzyme A or its derivatives + H2O = 3',5'-ADP + 4'-phosphopantetheine.


thalamus development

The process in which the thalamus changes over time, from its initial formation to its mature state.


vesicle docking

The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.


olfactory learning

Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.


isoprenoid diphosphate phosphatase activity

Catalysis of the dephosphorylation of isoprenoid diphosphates.


protein ufmylation

Covalent attachment of the ubiquitin-like protein UFM1 to another protein.


cell proliferation involved in atrial ventricular junction remodeling

The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.


aromatic amino acid family biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).


myelination of anterior lateral line nerve axons

The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.


positive regulation of macrophage activation

Any process that stimulates, induces or increases the rate of macrophage activation.


trichome papilla formation

The aggregation, arrangement and bonding together of a set of components to form a trichome papilla.


short-day photoperiodism, flowering

A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.


trehalase activity

Catalysis of the hydrolysis of trehalose or a trehalose derivative.


renal system segmentation

The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.


low-affinity zinc ion transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


negative regulation of L-tyrosine import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import into the cell.


atrazine chlorohydrolase activity

Catalysis of the reaction: atrazine + H2O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H+.


pentitol catabolic process

The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.


leaf shaping

The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).


negative regulation of interleukin-35-mediated signaling pathway

Any process that decreases the rate, frequency or extent of an interleukin-35-mediated signaling pathway.


drought recovery

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.


negative regulation of intermediate mesodermal cell fate specification

Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.


negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.


retinoic acid receptor signaling pathway involved in somitogenesis

The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis.


negative regulation of vascular associated smooth muscle cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.


3-aci-nitropropanoate oxidase activity

Catalysis of the reaction: 3-aci-nitropropanoate + H2O + O2 = 3-oxopropanoate + H2O2 + nitrite.


threonyl-tRNA aminoacylation

The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. The threonyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a threonine-accetping tRNA.


skeletal muscle satellite cell commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.


detection of mechanical stimulus involved in sensory perception of pain

The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.


response to Gentian violet

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.


maltose O-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose.


proton binding

Binding to proton.


Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.


pigment biosynthetic process involved in pigment accumulation

The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.


regulation of tyrosine 3-monooxygenase activity

Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity.


CoA hydrolase activity

Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.


methyl-CpNpN binding

Binding to a methylated cytosine/unspecified/unspecified trinucleotide.


hepatoblast apoptotic process

Any apoptotic process in a hepatoblast.


telomere maintenance in response to DNA damage

Any process that occur in response to the presence of critically short or damaged telomeres.


negative regulation of glycine import across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell.


o-orsellinic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid.


dextrin transmembrane transporter activity

Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of a membrane to the other.


Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.


angiotensin-activated signaling pathway involved in heart process

An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.


RNA-directed DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.


histone pre-mRNA stem-loop binding

Binding to a conserved stem-loop structure found in histone pre-mRNAs.


fasciculation of sensory neuron axon

The collection of sensory neuron axons into a bundle of rods, known as a fascicle.


pelargonidin 3-O-glucoside 7-O-glucosyltransferase (feruloyl-glucose dependent) activity

Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-feruloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + ferulate + H+.


lateral line development

The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.


negative regulation of detection of mechanical stimulus involved in sensory perception of touch

Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.


Catalysis of the reaction:(+)-amorpha-4,11-diene + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = (+)-artemisinate + 4 H+ + 4 H2O + 3 oxidized [NADPH--hemoprotein reductase].


shoot apical meristem development

The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure.


red, far-red light phototransduction

The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.


protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine

The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine.


Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate.


dibenzo-p-dioxin catabolic process

The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.


The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-).


regulation of fibroblast proliferation

Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.


protein xylosyltransferase activity

Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.


positive regulation of ribosomal small subunit export from nucleus

Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus.


nicotinamide riboside metabolic process

The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.


interleukin-15 production

The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


regulation of cardiocyte differentiation

Any process that modulates the frequency, rate or extent of cardiocyte differentiation.


retrograde trans-synaptic signaling by trans-synaptic protein complex

Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.


structural constituent of chitin-based larval cuticle

The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster.


antigen processing and presentation of endogenous antigen

The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.


DIBOA-glucoside oxygenase activity

Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide.


glycosylceramide biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.


sugar mediated signaling pathway

The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.


prenyl-FMNH2 binding

Binding to prenyl-FMNH2, a flavin mononucleotide obtained by prenylation of the N-10 position of FMNH2 followed by cyclisation. An essential cofactor for the decarboxylase enzymes UbiD and Fdc1.


p-cumate 2,3-dioxygenase activity

Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.


response to type II interferon

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.


positive regulation by host of viral genome replication

A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication.


(S)-limonene 1,2-monooxygenase activity

Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide.


regulation of tolerance induction

Any process that modulates the frequency, rate, or extent of tolerance induction.


antigen processing and presentation of lipid antigen via MHC class Ib

The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.


methylglutamate dehydrogenase activity

Catalysis of the reaction: N-methyl-L-glutamate + A + H2O = L-glutamate + AH(2) + formaldehyde.


maintenance of seed dormancy by absisic acid

The process by which seed dormancy is maintained by the presence of absisic acid.


tyrosine-tRNA ligase activity

Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H+.


metanephric S-shaped body morphogenesis

The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.


vascular associated smooth muscle cell dedifferentiation

The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.


glucan 1,4-beta-glucosidase activity

Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.


club cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.


abducens nucleus development

The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.


polysome binding

Binding to a polysome.


divinyl chlorophyllide a 8-vinyl-reductase activity

Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+.


Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.


response to codeine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.


negative regulation of synaptic transmission, dopaminergic

Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.


Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.


negative regulation of uterine smooth muscle contraction

Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction.


C21-steroid hormone metabolic process

The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.


cytochrome-b5 reductase activity, acting on NAD(P)H

Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5).


negative regulation of Schwann cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.


axon regeneration

The regrowth of axons following their loss or damage.


tetrahydrodictyopterin binding

Binding to tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.


endoribonuclease activity, cleaving siRNA-paired mRNA

Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.


sieve element differentiation

The process whereby a relatively unspecialized cell acquires specialized features of a sieve element.


negative regulation of mature B cell apoptotic process

Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.


Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.


limonene monooxygenase activity

Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene.


neurotrophin signaling pathway

The series of molecular signals initiated by neurotrophin binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.


aspartoacylase activity

Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.


acyl binding

Binding to an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.


acquisition of mycelium reproductive competence

A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium.


2,4-dichlorophenoxyacetic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.


subpallium cell migration

The orderly movement of cells from one site to another in the subpallium.


Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine.


positive regulation of starch metabolic process

Any process that activates or increases the frequency, rate or extent of starch metabolic process.


Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.


establishment of synaptic specificity at neuromuscular junction

The biological process in which a synapse between a motor neuron and a muscle is initially formed.


ovarian follicle endowment

Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.


positive regulation of age-related resistance

Any process that activates or increases the extent of age-related resistance.


Glc3Man9GlcNAc2 oligosaccharide glucosidase activity

Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).


carbohydrate storage

The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.


ciliary basal body segregation

The process in which the duplicated basal bodies migrate in pairs to the mitotic poles of the nucleus and results in equal distribution in the daughter cells. Ciliary basal body segregation ensures inheritance of the duplicated mitochondrial DNA to the two daughter cells in the Trypanosoma parasites.


fungal sorus development

The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.


5-methylcytosine biosynthetic process

The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA.


renal vesicle development

The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.


cellular response to copper ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.


maintenance of dense core granule location

Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.


hydrocarbon metabolic process

The chemical reactions and pathways involving a hydrocarbon, a compound consisting of carbon and hydrogen only.


Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.


positive regulation of determination of dorsal identity

Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.


exo-alpha-sialidase activity

Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.


olfactory cortex development

The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.


alpha-1,3-mannosyltransferase activity

Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.


negative regulation of female gonad development

Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.


(-)-isopiperitenone reductase activity

Catalysis of the reaction: (6R)-isoperitenone + H+ + NADPH = (2R,5R)-isopulegone + NADP+.


Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H+.


response to oomycetes

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.


(+)-kotanin metabolic process

The chemical reactions and pathways involving (+)-kotanin.


lupan-3beta,20-diol synthase activity

Catalysis of the reaction: lupan-3beta,20-diol <=> (S)-2,3-epoxysqualene + H2O.


negative regulation of the force of heart contraction

Any process that decreases the force of heart muscle contraction.


D-glycero-D-manno-heptose 7-phosphate metabolic process

The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate.


response to genistein

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.


plastid organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.


negative regulation of apoptotic process involved in metanephric nephron tubule development

Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.


benzoyl-CoA reductase activity

Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H2O + benzoyl-CoA + reduced ferredoxin.


CD4-positive or CD8-positive, alpha-beta T cell lineage commitment

The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.


regulation of adenosine receptor signaling pathway

Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.


trimethyllysine dioxygenase activity

Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O2 = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO2 + succinate.


T cell anergy

Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.


mitotic prometaphase

The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.


glycolytic fermentation to ethanol

The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.


regulation of platelet-derived growth factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.


positive regulation of cellular response to gamma radiation

Any process that activates or increases the frequency, rate or extent of cellular response to gamma radiation.


Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol.


leukocyte migration involved in inflammatory response

The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.


pyrimidodiazepine synthase activity

Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.


retinal cone cell development

Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.


deep nuclear neuron cell migration

The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.


regulation of membrane depolarization during action potential

Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential.


negative regulation of anthocyanin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process.


ABC-type ferric hydroxamate transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).


response to triglyceride

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.


ERK1 and ERK2 cascade

An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade may involve 4 different kinases, as it can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.


response to prostaglandin I

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


Atg12 ligase activity

Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.


NADH dehydrogenase complex assembly

The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.


proximal/distal pattern formation involved in mesonephric nephron development

The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).


doxorubicin metabolic process

The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy.


positive regulation of lipid transport across blood-brain barrier

Any process that activates or increases the frequency, rate or extent of lipid transport across blood-brain barrier.


box C/D RNA 5'-end processing

Any process involved in forming the mature 5' end of a box C/D RNA molecule.


anatomical structure maturation

A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.


epithelial cell proliferation involved in liver morphogenesis

The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.


regulation of granulosa cell proliferation

Any process that modulates the frequency, rate or extent of granulosa cell proliferation.


adhesion of symbiont infection structure to host

The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.


singlet oxygen-mediated programmed cell death

Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.


dimethylamine dehydrogenase activity

Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine.


cyanogenic glycoside biosynthetic process

The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.


regulation of complement activation, alternative pathway

Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.


D-alanine transmembrane transporter activity

Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.


post-embryonic genitalia morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.


beta-catenin destruction complex binding

Binding to a beta-catenin destruction complex.


protein localization to vacuolar membrane

A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.


The series of molecular signals initiated by interleukin-15 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


mesenchymal stem cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


regulation of retinal cone cell fate commitment

Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.


Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.


beta-N-acetylgalactosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.


tropomyosin kinase activity

Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin.


trialkylsulfonium hydrolase activity

Catalysis of the hydrolysis of a thioether bond, -S-.


regulation of synaptic transmission, cholinergic

Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


esculetin glucosyltransferase activity

Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+.


regulation of tube diameter

Any process that modulates the diameter of a tube.


glutamyl-tRNA aminoacylation

The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. The glutamyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a glutamic acid-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


arsenate reductase (azurin) activity

Catalysis of the reaction: H2O + arsenite + 2 oxidized azurin = 2 H+ + 2 reduced azurin + arsenate.


deoxycytidine deaminase activity

Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.


cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration

The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H+ + phosphatidyl-N-methylethanolamine.


organism emergence from protective structure

The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.


arabinoxylan-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of an arabinoxylan.


intercalary leaflet morphogenesis

The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.


[cytochrome c]-methionine S-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.


Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.


posterior midgut development

The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure.


protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine

The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.


The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes.


envenomation resulting in modulation of complement activation, lectin pathway in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism.


cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity

Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A.


reduced coenzyme F420 oxidase activity

Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O.


UGG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UGG codon.


aspartyl esterase activity

Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.


regulation of preblastoderm mitotic cell cycle

A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle.


ribosylpyrimidine nucleosidase activity

Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.


amino acid catabolic process to carboxylic acid via Ehrlich pathway

The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.


negative regulation of intestinal absorption

Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption.


positive regulation of mineralocorticoid secretion

Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.


B cell chemotaxis

The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).


positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.


AMP catabolic process

The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate.


phosphocholine hydrolase activity

Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.


negative regulation of cell cycle checkpoint

Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.


entry into host through the stromata

Entry of a symbiont into host plant tissue via the stromata, microscopic pores in the epidermis of the aerial parts of terrestrial plants. These pores are essential for photosynthesis, as they allow CO2 to diffuse into the plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of neuronal signal transduction

Any process that modulates the frequency, rate or extent of neuronal signal transduction.


negative regulation of cellular response to vascular endothelial growth factor stimulus

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.


lipopolysaccharide metabolic process

The chemical reactions and pathways involving lipopolysaccharides, a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.


regulation of muscle adaptation

Any process that modulates the frequency, rate or extent of muscle adaptation.


induction by symbiont of tumor or growth in host

The process in which a symbiont causes the formation of a mass of cells in a host organism. While these growths are often called nodules, they are not formed as nitrogen-fixing structures, but rather to provide an environment for the symbiont to grow. In this sense they are parasitic structures rather than mutualistic.


histone H3 deacetylation

The modification of histone H3 by the removal of one or more acetyl groups.


posterior lateral line nerve glial cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.


regulation of locomotor rhythm

Any process that modulates the frequency, rate or extent of locomotor rhythm.


histone H4R3 methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to the arginine residue at position 3 of histone H4, producing histone H4R3me.


positive regulation of microglial cell mediated cytotoxicity

Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.


mesonephric juxtaglomerulus cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.


peptidyl-arginine omega-N-methylation

The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.


dihydroorotate dehydrogenase (fumarate) activity

Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.


3',5'-cyclic diguanylic acid metabolic process

The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine.


beta-carotene 3-hydroxylase activity

Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O.


dimethyl sulfide monooxygenase activity

Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde.


Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.


histidinol dehydrogenase activity

Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.


water-soluble vitamin metabolic process

The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.


G protein-coupled photoreceptor activity

Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


ubiquinone biosynthetic process from chorismate

The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.


8-oxo-(d)RTP hydrolase activity

Catalysis of the reaction: 8-oxo-(d)RTP + H20 = 8-oxo-(d)RMP + diphosphate + H+.


CDP catabolic process

The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.


MHC class I receptor activity

Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.


cellular response to differentiation-inducing factor 1

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.


2',3'-cyclic GMP-AMP binding

Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.


ethanol catabolic process

The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.


negative regulation by symbiont of host intracellular transport

Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.


trigeminal ganglion development

The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.


SHREC complex localization

Any process in which a SHREC complex is transported to, or maintained in, a specific location.


chondrocyte morphogenesis

The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.


negative regulation of neuroinflammatory response

Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response.


sarcomerogenesis

The process in which sarcomeres are added in series within a fiber.


reproductive behavior

The specific behavior of an organism that is associated with reproduction.


regulation of anthocyanin metabolic process

Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.


protein histidine pros-kinase activity

Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.


Catalysis of the reaction: N-succinyl-L-glutamate + H2O = L-glutamate + succinate.


prephenate(2-) metabolic process

The chemical reactions and pathways involving prephenate(2-).


negative regulation of CD4-positive, alpha-beta T cell costimulation

Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.


positive regulation of platelet formation

Any process that activates or increases the frequency, rate or extent of platelet formation.


atrial cardiac muscle tissue development

The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.


regulation of fibroblast chemotaxis

Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.


structural constituent of chromatin

The action of a molecule that contributes to the structural integrity of chromatin.


emericellamide A catabolic process

The chemical reactions and pathways resulting in the breakdown of emericellamide A.


oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.


modulation by virus of host molecular function

The process in which a virus effects a change in the function of a host protein via a direct interaction.


regulation of collecting lymphatic vessel constriction

Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.


epoxyqueuosine reductase activity

Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.


(S)-carnitine 3-dehydrogenase activity

Catalysis of the reaction: (S)-carnitine + NAD+ = 3-dehydrocarnitine + H+ + NADH.


beta-caryophyllene catabolic process

The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.


negative regulation of cardiac muscle contraction

Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.


organophosphate ester transmembrane transporter activity

Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.


reactive oxygen species metabolic process

The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.


embryonic retina morphogenesis in camera-type eye

The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.


argininosuccinate synthase activity

Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.


NAD-dependent protein deacetylase activity

Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.


dermal bone morphogenesis

The process in which bone which forms superficially in the organism are generated and organized.


regulation of interleukin-17-mediated signaling pathway

Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.


response to dehydroepiandrosterone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.


chimeric colonial development

Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.


interleukin-25 receptor activity

Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


chaeta development

The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.


p-coumaroyltriacetic acid lactone synthase activity

Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide.


negative regulation of iron export across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of export of iron ions from inside of a cell, across the plasma membrane and into the extracellular region.


Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.


rhombomere 1 formation

The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


cannabinoid signaling pathway

A G protein-coupled receptor signaling pathway initiated by a cannabinoid binding to its receptor on the cell surface, and ending with the regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.


regulation of acylglycerol transport

Any process that modulates the frequency, rate or extent of acylglycerol transport.


capsorubin metabolic process

The chemical reactions and pathways involving capsorubin.


hemocyte migration

The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.


aflatoxin reductase (coenzyme F420) activity

Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.


polymeric immunoglobulin binding

Binding to a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.


positive regulation of gastric acid secretion

Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.


oocyte animal/vegetal axis specification

The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.


candelabrum cell differentiation

The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


regulation of L-tyrosine import across plasma membrane

Any process that modulates the frequency, rate or extent of L-tyrosine import into the cell.


The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.


acyl-CoA oxidase activity

Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.


cyclohexadienyl dehydrogenase activity

Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.


Catalysis of the reaction: L-dopa + O2 + H2O + H+ <=> 3,4-dihydroxyphenylacetaldehyde + CO2 + NH(4)+ + H2O2.


positive regulation of mesenchymal cell apoptotic process involved in metanephros development

Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.


antennal joint morphogenesis

The process in which the anatomical structures of the antennal joint are generated and organized.


tetraterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.


Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3.


maintenance of blood vessel diameter homeostasis by renin-angiotensin

The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.


symbiont-mediated suppression of host receptor-mediated signal transduction

A process in which a virus interferes with, inhibits or disrupts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of vascular associated smooth muscle cell membrane depolarization

Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.


modulation of symbiont haustorium neck formation for entry into host

Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


response to benzoic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.


negative regulation of muscle adaptation

Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.


nucleoside phosphotransferase activity

Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.


regulation of systemic arterial blood pressure by capillary fluid shift

The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.


violaceol II catabolic process

The chemical reactions and pathways resulting in the breakdown of violaceol II.


teichoic acid metabolic process

The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.


hindbrain formation

The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.


R-linalool synthase activity

Catalysis of the reaction: geranyl diphosphate + H2O = (R)-linalool + diphosphate.


Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.


eye photoreceptor cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.


dihydromonapterin reductase activity

Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.


response to interleukin-7

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.


negative regulation of fibroblast growth factor receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.


ligase activity, forming carbon-sulfur bonds

Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.


regulation of smoothened signaling pathway

Any process that modulates the frequency, rate or extent of smoothened signaling.


regulation of raffinose metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.


trifid subdivision of terminal units involved in ureteric bud branching

The process in which a ureteric bud splits into three units at its end.


negative regulation of potassium ion transmembrane transport

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.


Catalysis of the reaction: RMP + diphosphate = R + 5-phospho-alpha-D-ribose 1-diphosphate.


nephrostome development

The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.


cysteine transmembrane transporter activity

Enables the transfer of cysteine from one side of a membrane to the other.


dermatan 6-sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.


gallate decarboxylase activity

Catalysis of the reaction: gallate + H+ = CO2 + pyrogallol.


protein maturation by protein folding

The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.


GTP cyclohydrolase IIa activity

Catalysis of the reaction: GTP + 3 H2O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H+ + 2 phosphate.


myotome development

The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.


positive regulation of maltoheptaose transport

Any process that activates or increases the frequency, rate or extent of maltoheptaose transport.


negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH

Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.


Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.


regulation of cytokinin-activated signaling pathway

Any process that modulates the frequency, rate or extent of cytokinin signaling.


S-nitrosoglutathione reductase activity

Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+.


nitrilotriacetate metabolic process

The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.


Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.


coniferin metabolic process

The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.


Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+.


type III interferon production

The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.


sensory perception of cold stimulus

The series of events required for an organism to receive a cold temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal.


pre-miRNA 3'-end processing

Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.


seed germination

The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.


positive regulation of maltotetraose transport

Any process that activates or increases the frequency, rate or extent of maltotetraose transport.


lung proximal/distal axis specification

The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.


crying behavior

The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.


retinol transmembrane transporter activity

Enables the transfer of retinol from one side of a membrane to the other. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.


16S rRNA (guanine(966)-N(2))-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.


Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+.


phosphinothricin metabolic process

The chemical reactions and pathways involving phosphinothricin.


positive regulation of circadian sleep/wake cycle, non-REM sleep

Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.


alpha-carotene epsilon hydroxylase activity

Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.


rhamnose biosynthetic process

The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.


chondrocyte development

The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.


regulation of microtubule-based movement

Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.


glycolytic process from glycerol

The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH.


regulation of basidiospore formation

Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.