1,1,2-trichloroethene reductive dehalogenase activity

Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.


cellular response to external biotic stimulus

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.


lateral motor column neuron differentiation

The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.


reactive gliosis

A neuroinflammatory response, occurring over several days, during which glial cells undergo nonspecific reactive changes in response to damage to the central nervous system (CNS); typically involves the proliferation or hypertrophy of different types of glial cells.


Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine.


glycine dehydrogenase (decarboxylating) activity

Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.


oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.


cardioblast migration to the midline involved in heart rudiment formation

The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.


negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.


negative regulation of planar cell polarity pathway involved in heart morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.


negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.


negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.


negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.


negative regulation of planar cell polarity pathway involved in pericardium morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.


synaptic vesicle tethering involved in synaptic vesicle exocytosis

The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion.


P2Y5 nucleotide receptor binding

Binding to a P2Y5 nucleotide receptor.


bacterial-type flagellum rotor complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The rotor complex of the bacterial-type flagellum consists of a membrane-anchored ring and the motor switch complex, which participates in the conversion of proton/Na+ energy into the mechanical work of rotation and controls the direction of flagellar rotation.


formamide biosynthetic process

The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid.


D-tagatose 6-phosphate metabolic process

The chemical reactions and pathways involving a D-tagatose 6-phosphate.


peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine

The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.


lateral mesoderm morphogenesis

The process in which the anatomical structures of the lateral mesoderm are generated and organized.


nephrogenic mesenchyme development

The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.


mitochondrial tricarboxylic acid cycle enzyme complex

Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.


succinate-CoA ligase complex (GDP-forming)

A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.


mitochondrial alpha-ketoglutarate dehydrogenase complex

Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.


mitochondrial isocitrate dehydrogenase complex (NAD+)

Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity.


mitochondrial oxoglutarate dehydrogenase complex

A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide) (E1), dihydrolipoamide S-succinyltransferase (E2) and dihydrolipoamide dehydrogenase (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.


Catalysis of the reaction: 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + 2 H2O.


regulation of nucleotide biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.


regulation of cellular metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.


regulation of reactive oxygen species metabolic process

Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.


regulation of interleukin-1 production

Any process that modulates the frequency, rate, or extent of interleukin-1 production.


regulation of chemokine production

Any process that modulates the frequency, rate, or extent of chemokine production.


regulation of heterochromatin formation

Any process that modulates the frequency, rate, extent or location of heterochromatin formation.


positive regulation of mating-type specific transcription, DNA-templated

Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription.


negative regulation of gene expression via CpG island methylation

An epigenetic gene regulation mechanism that negatively regulates gene expression by methylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.


regulation of inositol phosphate biosynthetic process

Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


negative regulation of triglyceride metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.


positive regulation of double-strand break repair via nonhomologous end joining

Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.


regulation of DNA recombination

Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.


regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA

Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.


regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts

Any process that modulates the rate, frequency, or extent of selective degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


positive regulation of inositol phosphate biosynthetic process

Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


regulation of transcription initiation by RNA polymerase II

Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.


regulation of guanylate cyclase activity

Any process that modulates the frequency, rate or extent of guanylate cyclase activity.


regulation of phosphatidylglycerol biosynthetic process

Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process.


regulation of ncRNA transcription

Any process that modulates the frequency, rate or extent of transcription of a non-protein coding gene from a DNA-template.


regulation of tatiopterin biosynthetic process

Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process.


regulation of selenocysteine metabolic process

Any process that modulates the frequency, rate or extent of selenocysteine metabolic process.


regulation of nonadec-1-ene metabolic process

Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process.


positive regulation of iron-sulfur cluster assembly

Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly.


regulation of ethylene biosynthetic process

Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.


positive regulation of cellular biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.


maternal-to-zygotic transition of gene expression

Any process that modulates the frequency, rate or extent of gene expression by which developmental control passes from the maternal genome to the zygotic genome.


negative regulation of methyl-branched fatty acid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.


regulation of reticulophagy

Any process that modulates the frequency, rate or extent of reticulophagy.


regulation of mitotic cell cycle DNA replication

Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.


negative regulation of tetrapyrrole metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.


regulation of antibacterial peptide secretion

Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.


regulation of cutin biosynthetic process

Any process that modulates the frequency, rate or extent of cutin biosynthetic process.


positive regulation of purine nucleotide catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


regulation of antifungal peptide secretion

Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.


negative regulation of toluene metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process.


regulation of transcription from RNA polymerase II promoter by glucose

Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.


negative regulation of interleukin-1 alpha production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.


negative regulation of carotenoid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.


regulation of dosage compensation by inactivation of X chromosome

Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.


negative regulation of transforming growth factor beta1 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.


regulation of transforming growth factor beta3 production

Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.


positive regulation of vitamin E biosynthetic process

Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.


positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.


negative regulation of macrophage colony-stimulating factor production

Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production.


regulation of hydrogen peroxide metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.


regulation of cell wall (1->3)-beta-D-glucan biosynthetic process

Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


programmed DNA elimination by elimination of internal DNA segments

A programmed DNA elimination mechanism in which specific sequences, namely, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the genome. This process is known to occur in ciliates.


negative regulation of interleukin-37 production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-37 production.


transitive RNA interference

An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence.


epigenetic programming in the central cell

The establishment of epigenetic modifications (imprints) in a plant central cell, leading to an asymmetry between the two maternal alleles and the paternal allele, and differential expression of the corresponding alleles in the developing endosperm. This can happen through heterochromatin formation or differential chromatin loop formation.


positive regulation of pyrimidine nucleobase metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.


regulation of phosphatidylserine metabolic process

Any process that modulates the frequency, rate or extent of phosphatidylserine metabolic process.


regulation of aggrephagy

Any process that modulates the frequency, rate or extent of aggrephagy.


positive regulation of chemokine (C-X-C motif) ligand 2 production

Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.


positive regulation of methane biosynthetic process from trimethylamine

Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine.


regulation of restriction endodeoxyribonuclease activity

Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


regulation of (R)-mevalonic acid biosynthetic process

Any process that modulates the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.


nitrogen catabolite regulation of transcription

A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.


positive regulation of tetrapyrrole biosynthetic process

Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.


positive regulation of phospholipid metabolic process

Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.


positive regulation of nuclear cell cycle DNA replication

Any process that activates or increases the frequency, rate or extent of the DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.


negative regulation of triglyceride catabolic process

Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.


regulation of ent-pimara-8(14),15-diene biosynthetic process

Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.


positive regulation of interleukin-21 production

Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.


negative regulation of transforming growth factor beta2 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.


negative regulation of methanophenazine metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process.


regulation of siRNA-dependent facultative heterochromatin formation

Any process that modulates the frequency, rate or extent of siRNA-dependent facultative heterochromatin formation.


positive regulation of transcription from a mobile element promoter

Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.


negative regulation of interleukin-26 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.


positive regulation of reactive oxygen species metabolic process

Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.


negative regulation of phosphatidylinositol biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.


positive regulation of chlorophyll catabolic process

Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process.


positive regulation of piRNA transcription

Any process that increases the frequency, rate or extent of the synthesis of piRNA.


negative regulation of (+)-kotanin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.


regulation of type II interferon production

Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.


positive regulation of transcription by transcription factor localization

Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.


regulation of interleukin-34 production

Any process that modulates the frequency, rate or extent of interleukin-34 production.


regulation of error-prone translesion synthesis

Any process that modulates the frequency, rate or extent of error-prone translesion synthesis.


regulation of transcription by galactose

Any process involving galactose that modulates the frequency, rate or extent or transcription.


siRNA-mediated facultative heterochromatin formation

The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering RNA.


regulation of transcription from RNA polymerase II promoter in response to stress

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


positive regulation of heptadecane biosynthetic process

Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process.


regulatory ncRNA-mediated post-transcriptional gene silencing

A posttranscriptional gene silencing pathway in which regulatory RNAs elicit silencing of specific target genes, either by mRNA destabilization or inhibition of translation.


regulation of T cell cytokine production

Any process that modulates the frequency, rate, or extent of T cell cytokine production.


regulation of interleukin-5 production

Any process that modulates the frequency, rate, or extent of interleukin-5 production.


positive regulation of macromolecule biosynthetic process

Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


regulation of cyclic nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.


negative regulation of violaceol II biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process.


regulation of serotonin biosynthetic process

Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.


regulation of violaceol I biosynthetic process

Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.


regulation of cytochrome-c oxidase activity

Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.


regulation of cellular catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.


positive regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


positive regulation of diacylglycerol kinase activity

Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity.


negative regulation of chemokine (C-X-C motif) ligand 1 production

Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.


nitrogen catabolite activation of transcription

A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.


regulation of pteridine metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine.


regulation of granulocyte colony-stimulating factor production

Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.


tRNA destabilization

Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.


regulation of methanophenazine metabolic process

Any process that modulates the frequency, rate or extent of methanophenazine metabolic process.


dosage compensation by inactivation of X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.


negative regulation of mast cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.


negative regulation of monocyte chemotactic protein-1 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.


positive regulation of tatiopterin biosynthetic process

Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process.


regulation of pentadecane biosynthetic process

Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process.


regulation of DNA-templated DNA replication

Any process that modulates the rate, frequency, or extent of DNA-templated DNA replication, the process in which new strands of DNA are synthesized.


positive regulation of antisense RNA transcription

Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.


regulation of mitochondrial ATP synthesis coupled electron transport

Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.


positive regulation of glycolytic process through fructose-6-phosphate

Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.


regulation of miRNA metabolic process

Any process that modulates the frequency, rate or extent of miRNA metabolic process.


regulation of interleukin-15 production

Any process that modulates the frequency, rate, or extent of interleukin-15 production.


silent mating-type cassette heterochromatin formation

Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.


negative regulation of bile acid metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process.


negative regulation of transforming growth factor beta3 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.


regulation of RNA polymerase III activity

Any process that modulates the frequency, rate or extent of RNA polymerase III activity.


regulation of regulatory ncRNA-mediated heterochromatin formation

Any process that modulates the frequency, rate or extent of small non-coding RNA-mediated heterochromatin formation.


positive regulation of DNA-binding transcription factor activity

Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.


positive regulation of hydrogen peroxide biosynthetic process

Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.


regulation of phenazine biosynthetic process

Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.


regulation of type III site-specific deoxyribonuclease activity

Any process that modulates the frequency, rate or extent of a type III restriction endodeoxyribonuclease activity.


negative regulation of natural killer cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.


regulation of vitamin A metabolic process

Any process that modulates the frequency, rate or extent of vitamin A metabolic process.


regulation of lipid kinase activity

Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.


regulation of transcription from RNA polymerase II promoter in response to iron

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus.


negative regulation of pentadecane biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process.


regulation of amylopectin catabolic process

Any process that modulates the frequency, rate or extent of amylopectin catabolic process.


positive regulation of telomere maintenance in response to DNA damage

Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.


positive regulation of antimicrobial peptide secretion

Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.


negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA

Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.


positive regulation of juvenile hormone catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.


positive regulation of myeloid dendritic cell cytokine production

Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.


regulation of interleukin-11 production

Any process that modulates the frequency, rate, or extent of interleukin-11 production.


negative regulation of interleukin-34 production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-34 production.


regulation of pectin biosynthetic process

Any process that modulates the frequency, rate or extent of pectin biosynthetic process.


regulation of hexadecanal metabolic process

Any process that modulates the frequency, rate or extent of hexadecanal metabolic process.


positive regulation of phosphatidylglycerol biosynthetic process

Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process.


negative regulation of cellular metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.


regulation of interleukin-33 production

Any process that modulates the frequency, rate or extent of interleukin-33 production.


regulation of chemokine (C-C motif) ligand 4 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.


regulation of interleukin-37 production

Any process that modulates the frequency, rate or extent of interleukin-37 production.


regulation of apoptotic DNA fragmentation

Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.


positive regulation of type III interferon production

Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


negative regulation of syringal lignin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.


positive regulation of chemokine (C-C motif) ligand 1 production

Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


negative regulation of reactive oxygen species metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.


negative regulation of interleukin-16 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.


positive regulation of pentadecane metabolic process

Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process.


regulation of 4,6-pyruvylated galactose residue biosynthetic process

Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.


post-transcriptional regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.


lncRNA-mediated post-transcriptional gene silencing

A post-transcriptional gene silencing pathway in which regulatory long noncoding RNAs (lncRNAs) elicit silencing of specific target genes, often miRNAs or mRNAs.


positive regulation of ergosterol biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.


regulation of phospholipid metabolic process

Any process that modulates the frequency, rate or extent of phospholipid metabolic process.


positive regulation of aggrephagy

Any process that activates or increases the frequency, rate or extent of aggrephagy.


positive regulation of MHC class I biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.


regulation of cellular organofluorine metabolic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.


regulation of phospholipid catabolic process

Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.


negative regulation of hydrogen peroxide catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process.


regulation of telomere maintenance via telomere lengthening

Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.


negative regulation of nitric-oxide synthase biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.


negative regulation of kinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


negative regulation of cardiolipin metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process.


positive regulation of 3'-UTR-mediated mRNA stabilization

Any process that activates or increases the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.


regulation of cell wall chitin biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin.


regulation of DNA strand resection involved in replication fork processing

Any process that modulates the frequency, rate or extent of DNA strand resection involved in replication fork processing.


positive regulation of bile acid metabolic process

Any process that activates or increases the frequency, rate or extent of bile acid metabolic process.


regulation of pyrimidine nucleotide biosynthetic process

Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.


regulation of siRNA processing

Any process that modulates the frequency, rate or extent of siRNA processing.


negative regulation of UDP-glucose catabolic process

Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.


regulation of double-strand break repair via break-induced replication

Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication.


regulation of interleukin-4 production

Any process that modulates the frequency, rate, or extent of interleukin-4 production.


positive regulation of interleukin-7 production

Any process that activates or increases the frequency, rate, or extent of interleukin-7 production.


negative regulation of interleukin-20 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production.


negative regulation of interleukin-24 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production.


regulation of xenophagy

Any process that modulates the frequency, rate or extent of xenophagy.


positive regulation of single strand break repair

Any process that activates or increases the frequency, rate or extent of single strand break repair.


negative regulation of glycogen metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


regulation of phosphatidic acid biosynthetic process

Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process.


negative regulation of phosphatidylinositol 3-kinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity.


programmed DNA elimination

A process in which genomic fragments or entire chromosomes are eliminated from somatic cells or from micronuclei of ciliates. This process occurs in the developing macronucleus (anlage) of a ciliate, as well as in other species, including vertebrates and is an irreversible mechanism of gene silencing.


positive regulation of post-transcriptional gene silencing by RNA

Any process that activates or increases the frequency, rate or extent of post-transcriptional gene silencing by RNA.


negative regulation of interleukin-2 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.


positive regulation of cellular respiration

Any process that activates or increases the frequency, rate or extent of cellular respiration.


negative regulation of sarcinapterin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process.


regulation of MHC class II biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.


regulation of phosphorylation

Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.


positive regulation of fractalkine production

Any process that activates or increases the frequency, rate, or extent of fractalkine production.


regulation of sarcinapterin biosynthetic process

Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process.


negative regulation of glycogen catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.


negative regulation of cytochrome-c oxidase activity

Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity.


regulation of DNA-templated transcription elongation

Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.


regulation of lignin biosynthetic process

Any process that modulates the frequency, rate or extent of lignin biosynthetic process.


regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process

Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.


positive regulation of amylopectin metabolic process

Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process.


positive regulation of mRNA metabolic process

Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.


negative regulation of transforming growth factor beta production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.


regulation of alkaline phosphatase activity

Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.


negative regulation of cellular organofluorine metabolic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.


negative regulation of triglyceride biosynthetic process

Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.


regulation of toluene catabolic process

Any process that modulates the frequency, rate or extent of toluene catabolic process.


regulation of antimicrobial peptide secretion

Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.


negative regulation of granzyme A production

Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production.


positive regulation of serotonin biosynthetic process

Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.


positive regulation of strand invasion

Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


positive regulation of interleukin-13 production

Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.


positive regulation of interleukin-17 production

Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.


negative regulation of glycolytic process through fructose-6-phosphate

Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.


negative regulation of methane biosynthetic process from trimethylamine

Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine.


regulation of tridecane biosynthetic process

Any process that modulates the frequency, rate or extent of tridecane biosynthetic process.


negative regulation of beta 2 integrin biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.


negative regulation of diacylglycerol kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity.


negative regulation of autophagy

Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.


regulation of vascular endothelial growth factor production

Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.


regulation of [2Fe-2S] cluster assembly

Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly.


regulation of juvenile hormone metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.


transcription initiation-coupled chromatin remodeling

An epigenetic mechanism of regulation of gene expression that involves chromatin remodeling to capacitate gene expression by either modifying the chromatin fiber, the nucleosomal histones, or the DNA.


regulation of transforming growth factor beta production

Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.


negative regulation of reductive pentose-phosphate cycle

Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle.


negative regulation of tumor necrosis factor superfamily cytokine production

Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.


regulation of protection from non-homologous end joining at telomere

Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.


regulation of phospholipid biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


negative regulation of 3'-UTR-mediated mRNA stabilization

Any process that stops, prevents or reduces the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.


negative regulation of interleukin-3 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production.


negative regulation of cutin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process.


positive regulation of phospholipid catabolic process

Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.


negative regulation of phosphorus metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.


negative regulation of nitric oxide biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.


negative regulation of post-transcriptional gene silencing by regulatory ncRNA

Any process that stops, prevents or reduces the frequency, rate or extent of post-transcriptional gene silencing by RNA.


positive regulation of isoprene metabolic process

Any process that activates or increases the frequency, rate or extent of isoprene metabolic process.


positive regulation of citrulline biosynthetic process

Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process.


regulation of interleukin-18 production

Any process that modulates the frequency, rate, or extent of interleukin-18 production.


negative regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.


positive regulation of methane biosynthetic process from dimethyl sulfide

Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.


negative regulation of transforming growth factor beta3 activation

Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation.


regulation of sinapate ester biosynthetic process

Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis.


regulation of phosphate metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.


regulation of mitotic DNA replication initiation

Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.


negative regulation of melanization defense response

Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.


regulation of t-circle formation

Any process that modulates the frequency, rate or extent of t-circle formation.


positive regulation of selenocysteine metabolic process

Any process that activates or increases the frequency, rate or extent of selenocysteine metabolic process.


positive regulation of interleukin-24 production

Any process that activates or increases the frequency, rate, or extent of interleukin-24 production.


positive regulation of DNA repair

Any process that activates or increases the frequency, rate or extent of DNA repair.


positive regulation of regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process

Any process that activates or increases the frequency, rate or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process.


regulation of siRNA-independent facultative heterochromatin formation

Any process that modulates the frequency, rate or extent of siRNA-independent facultative heterochromatin assembly.


positive regulation of vascular endothelial growth factor production

Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.


regulation of methanophenazine biosynthetic process

Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process.


negative regulation of connective tissue growth factor production

Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.


negative regulation of glycolytic fermentation to ethanol

Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol.


negative regulation of reactive oxygen species biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.


regulation of telomere maintenance in response to DNA damage

Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.


regulation of cellular respiration

Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.


negative regulation of mitochondrial ATP synthesis coupled electron transport

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.


negative regulation of lysine biosynthetic process via aminoadipic acid

Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.


epigenetic programming in the endosperm

The global programming of epigenetic modifications following binucleate central cell fertilization. This involves DNA methylation at the silent allele. In the endosperm, maternal genomes are hypomethylated compared with the paternal genome.


regulation of mitotic recombination-dependent replication fork processing

Any process that modulates the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences.


regulation of rDNA heterochromatin formation

Any process that modulates the rate, frequency, or extent of rDNA heterochromatin formation.


regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway

Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.


regulation of starch biosynthetic process

An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.


regulation of transcription elongation by RNA polymerase I

Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.


regulation of sterigmatocystin biosynthetic process

Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.


positive regulation of cysteine metabolic process

Any process that activates or increases the frequency, rate or extent of cysteine metabolic process.


negative regulation of inositol trisphosphate biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.


positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.


regulation of phosphatidylcholine catabolic process

Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.


regulation of glucan biosynthetic process

Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.


regulation of oxidative phosphorylation

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.


positive regulation of androgen receptor activity

Any process that activates or increases the frequency, rate or extent of androgen receptor activity.


positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process

Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.


positive regulation of mitotic recombination

Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis.


positive regulation of chemokine (C-C motif) ligand 5 production

Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.


regulation of RNA polymerase II transcription preinitiation complex assembly

Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.


positive regulation of transcription by RNA polymerase I

Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase I.


positive regulation of telomerase RNA reverse transcriptase activity

Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity.


positive regulation of phosphorylation

Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.


positive regulation of fumagillin biosynthetic process

Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process.


regulation of proanthocyanidin biosynthetic process

Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.


regulation of purine nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.


negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity

Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.


regulation of snRNA pseudouridine synthesis

Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis.


regulation of tRNA stability

Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs.


positive regulation of plant-type cell wall cellulose biosynthetic process

Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.


negative regulation of [4Fe-4S] cluster assembly

Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly.


positive regulation of autophagy in response to ER overload

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The process in which the accumulation of misfolded proteins in the endoplasmic reticulum triggers a response that positively regulates autophagy.


regulation of T-helper 2 cell cytokine production

Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production.


regulation of transcription initiation by RNA polymerase I

Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter.


positive regulation of type II interferon production

Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.


positive regulation of acetylcholine biosynthetic process

Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process.


regulation of fructose 1,6-bisphosphate metabolic process

Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.


negative regulation of phosphatase activity

Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.


regulation of removal of superoxide radicals

Any process that modulates the frequency, rate or extent of removal of superoxide radicals.


negative regulation of [2Fe-2S] cluster assembly

Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly.


negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.


positive regulation of interleukin-8 production

Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.


regulation of telomerase RNA reverse transcriptase activity

Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity.


negative regulation of chemokine (C-X-C motif) ligand 2 production

Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.


positive regulation of cutin biosynthetic process

Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process.


positive regulation of cobalamin metabolic process

Any process that activates or increases the frequency, rate or extent of a cobalamin metabolic process.


positive regulation of beta 2 integrin biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.


positive regulation of pyocyanine biosynthetic process

Any process that increases the frequency, rate or extent of a pyocyanine biosynthetic process.


positive regulation of TRAIL production

Any process that activates or increases the frequency, rate, or extent of TRAIL production.


positive regulation of natural killer cell cytokine production

Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.


regulation of DNA biosynthetic process

Any process that modulates the frequency, rate or extent of DNA biosynthetic process.


positive regulation of methane biosynthetic process from dimethylamine

Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine.


positive regulation of autophagy

Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.


negative regulation of CREB transcription factor activity

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.


positive regulation of hexadecanal biosynthetic process

Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process.


negative regulation of T-helper 2 cell cytokine production

Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production.


regulation of mitochondrial gene expression

Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


regulation of transcriptional start site selection at RNA polymerase II promoter

Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.


negative regulation of chemokine (C-C motif) ligand 6 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.


positive regulation of nucleotide biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.


regulation of pericentric heterochromatin formation

Any process that modulates the frequency, rate or extent of heterochromatin formation at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.


regulation of B cell cytokine production

Any process that modulates the frequency, rate, or extent of B cell cytokine production.


regulation of octadecene metabolic process

Any process that modulates the frequency, rate or extent of octadecene metabolic process.


positive regulation of interleukin-9 production

Any process that activates or increases the frequency, rate, or extent of interleukin-9 production.


regulation of DNA strand elongation

Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.


regulation of superoxide anion generation

Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.


positive regulation of juvenile hormone biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.


regulation of telomere capping

Any process that modulates the frequency, rate or extent of telomere capping.


regulation of macromolecule biosynthetic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


negative regulation of ATP metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.


regulation of RNA stability

Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs.


negative regulation of photosynthesis

Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.


regulation of octadecene biosynthetic process

Any process that modulates the frequency, rate or extent of octadecene biosynthetic process.


negative regulation of ATP biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.


positive regulation of DNA strand elongation

Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.


regulation of meiotic DNA double-strand break formation

Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation.


positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine

Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.


negative regulation of inositol phosphate biosynthetic process

Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.


regulation of miRNA processing

Any process that modulates the frequency, rate or extent of microRNA processing.


positive regulation of transcription from RNA polymerase II promoter in response to stress

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).


negative regulation of transforming growth factor beta1 activation

Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation.


regulation of macrophage inflammatory protein-1 gamma production

Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.


positive regulation of myeloid leukocyte cytokine production involved in immune response

Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.


regulation of aflatoxin biosynthetic process

Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process.


positive regulation of mRNA 3'-end processing

Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.


regulation of hyaluronan biosynthetic process

Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.


negative regulation of juvenile hormone metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.


regulation of spermidine biosynthetic process

Any process that modulates the frequency, rate or extent of spermidine biosynthetic process.


positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process

Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process.


positive regulation of phosphatidylinositol biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.


positive regulation of mitochondrial DNA metabolic process

Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.


negative regulation of iron-sulfur cluster assembly

Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly.


positive regulation of transcription by glucose

Any process involving glucose that activates or increases the rate of transcription.


positive regulation of interleukin-2 production

Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.


regulation of beta 2 integrin biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.


negative regulation of interleukin-6 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.


positive regulation of quinolinate biosynthetic process

Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process.


negative regulation of citrulline biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.


regulation of citrulline biosynthetic process

Any process that modulates the frequency, rate or extent of citrulline biosynthetic process.


regulation of heptadecane metabolic process

Any process that modulates the frequency, rate or extent of heptadecane metabolic process.


regulation of methane biosynthetic process from carbon monoxide

Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide.


regulation of phytol biosynthetic process

Any process that modulates the frequency, rate or extent of phytol biosynthetic process.


regulation of post-transcriptional gene silencing

Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.


negative regulation of mitochondrial electron transport, NADH to ubiquinone

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.


carbon catabolite regulation of transcription from RNA polymerase II promoter

A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


negative regulation of cysteine metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process.


positive regulation of chemokine (C-C motif) ligand 4 production

Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.


positive regulation of granulocyte colony-stimulating factor production

Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.


regulation of interleukin-3 production

Any process that modulates the frequency, rate, or extent of interleukin-3 production.


negative regulation of interleukin-32 production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-32 production.


regulation of receptor catabolic process

Any process that modulates the frequency, rate or extent of receptor catabolic process.


negative regulation of integrin biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.


circadian regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.


positive regulation of interleukin-5 production

Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.


negative regulation of interleukin-5 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.


positive regulation of T cell cytokine production

Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.


regulation of antifungal peptide production

Any process that modulates the frequency, rate, or extent of antifungal peptide production.


negative regulation of demethylkotanin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process.


regulation of phosphorus utilization

Any process that modulates the frequency, rate or extent of phosphorus utilization.


regulation of tRNA metabolic process

Any process that modulates the frequency, rate or extent of tRNA metabolic process.


positive regulation of interleukin-37 production

Any process that activates or increases the frequency, rate or extent of interleukin-37 production.


regulation of phosphatidylinositol dephosphorylation

Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.


regulation of granzyme A production

Any process that modulates the frequency, rate or extent of granzyme A production.


positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA

Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.


post-transcriptional gene silencing

The inactivation of gene expression that occurs after transcription.


positive regulation of methyl-branched fatty acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.


positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.


positive regulation of ethylene biosynthetic process

Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process.


regulation of ribosomal protein gene transcription by RNA polymerase II

Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.


regulation of glial cell-derived neurotrophic factor production

Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor production.


negative regulation of granzyme B production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.


positive regulation of NAD+ kinase activity

Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.


negative regulation of oxygen metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.


regulation of mitochondrial transcription

Any process that modulates the frequency, rate or extent of transcription occuring in the mitochondrion.


negative regulation of antifungal peptide secretion

Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion.


positive regulation of cellular metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.


dosage compensation by hypoactivation of X chromosome

Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans.


positive regulation of DNA endoreduplication

Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.


regulation of iron-sulfur-molybdenum cofactor assembly

Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.


regulation of tRNA catabolic process

Any process that modulates the frequency, rate or extent of tRNA catabolic process.


positive regulation of B cell cytokine production

Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.


positive regulation of protection from non-homologous end joining at telomere

Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.


regulation of interleukin-20 production

Any process that modulates the frequency, rate, or extent of interleukin-20 production.


siRNA-independent facultative heterochromatin formation

The formation of facultative heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process independent of small interfering RNAs.


siRNA-mediated gene silencing

A post-transcriptional gene silencing pathway in which small interfering RNAs (siRNAs) elicit silencing of specific target genes. siRNAs are 21-23 nucleotide RNA duplexes that are fully complementary to their target mRNA. siRNAs can be exported and act in other cells, including in germline cells. Once incorporated into a RNA-induced silencing complex (RISC), siRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the mRNA or mRNA translational repression. siRNAs are present in lower animals and plants, but not found in mammals; whereas miRNAs are present in all the animals and in plants.


positive regulation of termination of RNA polymerase I transcription

Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription.


regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

Any process that modulates the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.


regulation of methane biosynthetic process from dimethylamine

Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine.


regulation of nucleotide metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.


positive regulation of mitochondrial mRNA catabolic process

Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.


regulation of DNA methylation-dependent heterochromatin formation

Any process that modulates the rate, frequency, or extent of DNA methylation-dependent heterochromatin formation.


regulation of interleukin-13 production

Any process that modulates the frequency, rate, or extent of interleukin-13 production.


pericentric heterochromatin formation

The compaction of chromatin located adjacent to the CENP-A rich centromere 'central core' and characterized by methylation of histone H3K9, into heterochromatin, resulting in the repression of transcription at pericentric DNA.


negative regulation of antimicrobial peptide production

Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.


nitrogen catabolite regulation of transcription from RNA polymerase II promoter

A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.


regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

Any process that modulates the frequency, rate or extent of a parkin-mediated process that positively regulates mitophagy in response to mitochondrial depolarization.


positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process

Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.


regulation of triglyceride catabolic process

Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.


positive regulation of glycine hydroxymethyltransferase activity

Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.


regulation of tetrapyrrole metabolic process

Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.


regulation of auxin biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.


positive regulation of electron transfer activity

Any process that activates or increases the frequency, rate or extent of electron transfer activity.


positive regulation of oxygen metabolic process

Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.


positive regulation of endothelin production

Any process that activates or increases the frequency, rate or extent of endothelin production.


positive regulation of cellulose biosynthetic process

Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.


regulation of initiation of premeiotic DNA replication

Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.


positive regulation of inositol trisphosphate biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.


regulation of ascospore wall chitin biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin.


positive regulation of DNA replication initiation

Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.


negative regulation of glycolytic process

Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.


regulation of aerobic respiration

Any process that modulates the frequency, rate or extent of aerobic respiration.


replication fork progression beyond termination site

Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks.


negative regulation of sterigmatocystin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process.


regulation of isoprene metabolic process

Any process that modulates the frequency, rate or extent of isoprene metabolic process.


regulation of amylopectin metabolic process

Any process that modulates the frequency, rate or extent of amylopectin metabolic process.


positive regulation of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity

Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.


programmed DNA elimination by chromosome breakage

Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.


positive regulation of lipid kinase activity

Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.


regulation of interleukin-16 production

Any process that modulates the frequency, rate, or extent of interleukin-16 production.


regulation of melanin biosynthetic process

Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.


positive regulation of glucose catabolic process to lactate via pyruvate

Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.


positive regulation of glycogen metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.


positive regulation of ribosomal protein gene transcription by RNA polymerase II

Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes mediated by RNA polymerase II.


regulation of monocyte chemotactic protein-1 production

Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.


positive regulation of 1-phosphatidylinositol-3-kinase activity

Any process that starts or increases the frequency or rate of 1-phosphatidylinositol-3-kinase activity.


regulation of 'de novo' NAD biosynthetic process from tryptophan

Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.


positive regulation of DNA recombination at centromere

Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.


positive regulation of double-strand break repair

Any process that activates or increases the frequency, rate or extent of double-strand break repair.


negative regulation of interleukin-9 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production.


negative regulation of dCDP biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process.


regulation of telomere maintenance via recombination

Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.


positive regulation of phosphatidylserine metabolic process

Any process that activates or increases the frequency, rate or extent of phosphatidylserine metabolic process.


regulation of type I site-specific deoxyribonuclease activity

Any process that modulates the frequency, rate or extent of a type I restriction endodeoxyribonuclease activity.


regulation of DNA recombination at centromere

Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.


positive regulation of mismatch repair

Any process that activates or increases the frequency, rate or extent of mismatch repair.


positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation

Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation.


positive regulation of cardiolipin metabolic process

Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.


regulation of termination of RNA polymerase I transcription

Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription.


inactivation of paternal X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex.


regulation of NADP metabolic process

Any process that modulates the frequency, rate or extent of NADP metabolic process.


regulation of orcinol biosynthetic process

Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.


regulation of interleukin-6 production

Any process that modulates the frequency, rate, or extent of interleukin-6 production.


positive regulation of DNA demethylation

Any process that activates or increases the frequency, rate or extent of DNA demethylation.


positive regulation of tetrapyrrole catabolic process

Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process.


positive regulation of acetylcholine metabolic process

Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


negative regulation of fumagillin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process.


regulation of methanofuran biosynthetic process

Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process.


positive regulation of macrophage inflammatory protein-1 gamma production

Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.


positive regulation of miRNA metabolic process

Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.


positive regulation of vitamin D biosynthetic process

Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).


negative regulation of granulocyte colony-stimulating factor production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.


positive regulation of granzyme A production

Any process that activates or increases the frequency, rate or extent of granzyme A production.


regulation of natural killer cell cytokine production

Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.


regulation of double-strand break repair via nonhomologous end joining

Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.


positive regulation of UDP-N-acetylglucosamine biosynthetic process

Any process that activates or increases the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.


negative regulation of chlorophyll biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.


regulation of DNA ligase activity

Any process that modulates the frequency, rate or extent of DNA ligase activity.


random inactivation of X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.


positive regulation of DNA-templated DNA replication initiation

Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.


positive regulation of tRNA metabolic process

Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.


regulation of methane biosynthetic process from dimethyl sulfide

Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.


regulation of catecholamine metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.


positive regulation of nucleotide metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.


regulation of DNA-templated DNA replication initiation

Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.


negative regulation of pyruvate kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.


regulation of dephosphorylation

Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.


regulation of glycogen catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.


positive regulation of interleukin-6 production

Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.