L7RGF5_9VIRU Uncharacterized protein (trembl)


L7RGF8_9VIRU Virion-associated membrane protein (trembl)


L7RGG1_9VIRU NAD-dependent DNA ligase (trembl)


L7RGH1_9VIRU Glycosyltransferase family 25 (trembl)


L7RGH6_9VIRU Patatin phospholipase (trembl)


L7RGJ3_9VIRU Putative transposase (trembl)


L7RGL5_9VIRU Arginyl-tRNA synthetase (trembl)


L7RGL7_9VIRU Virion-associated membrane protein (trembl)


L7RGM4_9VIRU Serine-threonine kinase (trembl)


L7RGQ5_9VIRU Protein Tyrosine Kinase (PTK) family protein (trembl)


L7RGR0_9VIRU Mitochondrial 18 kDa protein (trembl)


L7RGR2_9VIRU Uncharacterized protein (trembl)


L7RGR7_9VIRU tyrosine--tRNA ligase (trembl)


L7RGS0_9VIRU Uncharacterized protein (trembl)


L7RGS7_9VIRU Post-GPI attachment to proteins factor 3 (trembl)


A7K7X5_9PHYC Uncharacterized protein z015L (trembl)


A7K7Z5_9PHYC ribonucleoside-diphosphate reductase (trembl)


A7K800_9PHYC Uncharacterized protein Z040R (trembl)


A7K813_9PHYC Uncharacterized protein Z053L (trembl)


A7K821_9PHYC Sulfhydryl oxidase (trembl)


A7K823_9PHYC Uncharacterized protein Z063L (trembl)


A7K832_9PHYC Uncharacterized protein z072L (trembl)


A7K837_9PHYC Uncharacterized protein Z077L (trembl)


phosphoric diester hydrolase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.


A7K840_9PHYC Uncharacterized protein Z080L (trembl)


A7K841_9PHYC Uncharacterized protein Z081L (trembl)


protein disulfide isomerase activity

Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.


A7K843_9PHYC Uncharacterized protein z083R (trembl)


A7K844_9PHYC mRNA 5'-phosphatase (trembl)


A7K845_9PHYC Uncharacterized protein z085L (trembl)


A7K847_9PHYC Uncharacterized protein z087L (trembl)


A7K850_9PHYC Uncharacterized protein z090L (trembl)


A7K853_9PHYC Uncharacterized protein z093R (trembl)


A7K856_9PHYC Uncharacterized protein Z096L (trembl)


A7K860_9PHYC Uncharacterized protein Z100L (trembl)


A7K861_9PHYC Ribonucleoside-diphosphate reductase (trembl)


A7K890_9PHYC Uncharacterized protein z130R (trembl)


A7K891_9PHYC Uncharacterized protein Z131L (trembl)


A7K895_9PHYC Uncharacterized protein Z135R (trembl)


A7K8A2_9PHYC Uncharacterized protein z142L (trembl)


A7K8A5_9PHYC Uncharacterized protein z145L (trembl)


A7K8A7_9PHYC Uncharacterized protein Z147L (trembl)


A7K8A8_9PHYC Uncharacterized protein Z148L (trembl)


A7K8B1_9PHYC Uncharacterized protein Z151L (trembl)


A7K8B8_9PHYC Uncharacterized protein z158L (trembl)


A7K8B9_9PHYC Uncharacterized protein Z159R (trembl)


four-way junction DNA binding

Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.


A7K8C2_9PHYC Uncharacterized protein Z162R (trembl)


A7K8C6_9PHYC Uncharacterized protein z166L (trembl)


A7K8C8_9PHYC Uncharacterized protein z168L (trembl)


A7K8C9_9PHYC Uncharacterized protein Z169R (trembl)


A7K8D7_9PHYC Uncharacterized protein Z177L (trembl)


A7K8D8_9PHYC Uncharacterized protein Z178L (trembl)


A7K8E1_9PHYC Uncharacterized protein z181L (trembl)


A7K8E7_9PHYC Uncharacterized protein Z187L (trembl)


A7K8F0_9PHYC Uncharacterized protein Z190L (trembl)


A7K8F2_9PHYC Uncharacterized protein z192R (trembl)


A7K8F5_9PHYC Uncharacterized protein Z195R (trembl)


A7K8F6_9PHYC Uncharacterized protein z196R (trembl)


A7K8G0_9PHYC Uncharacterized protein z200L (trembl)


A7K8G4_9PHYC Uncharacterized protein Z204R (trembl)


chitosanase activity

Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.


carbohydrate metabolic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.


A7K8G9_9PHYC Uncharacterized protein Z209R (trembl)


A7K8H3_9PHYC Uncharacterized protein z213R (trembl)


A7K8H7_9PHYC Uncharacterized protein Z217R (trembl)


A7K8H8_9PHYC Uncharacterized protein z218L (trembl)


A7K8H9_9PHYC Uncharacterized protein Z219L (trembl)


A7K8I9_9PHYC Uncharacterized protein Z229L (trembl)


A7K8J0_9PHYC Uncharacterized protein Z230R (trembl)


A7K8J8_9PHYC Uncharacterized protein z238R (trembl)


A7K8J9_9PHYC Uncharacterized protein Z239R (trembl)


A7K8K4_9PHYC Uncharacterized protein z244R (trembl)


A7K8L0_9PHYC Uncharacterized protein z250R (trembl)


A7K8L2_9PHYC Uncharacterized protein z252L (trembl)


A7K8N0_9PHYC Uncharacterized protein Z270R (trembl)


A7K8N2_9PHYC Uncharacterized protein z272L (trembl)


A7K8N4_9PHYC Uncharacterized protein Z274R (trembl)


A7K8N7_9PHYC Uncharacterized protein z277R (trembl)


A7K8P0_9PHYC Uncharacterized protein Z280L (trembl)


A7K8P2_9PHYC Uncharacterized protein Z282L (trembl)


nucleotide-sugar biosynthetic process

The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.


A7K8P9_9PHYC Uncharacterized protein Z289L (trembl)


A7K8Q4_9PHYC Uncharacterized protein Z294L (trembl)


A7K8Q5_9PHYC Uncharacterized protein Z295L (trembl)


NAD binding

Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.


A7K8R0_9PHYC Uncharacterized protein Z300R (trembl)


channel activity

Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.


transmembrane transport

The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.


A7K8R9_9PHYC Uncharacterized protein Z309L (trembl)


A7K8S1_9PHYC Uncharacterized protein Z311R (trembl)


A7K8S7_9PHYC Uncharacterized protein z317L (trembl)


A7K8T1_9PHYC Uncharacterized protein Z321R (trembl)


A7K8T4_9PHYC Uncharacterized protein Z324R (trembl)


A7K8T5_9PHYC Uncharacterized protein z325L (trembl)


A7K8T8_9PHYC Uncharacterized protein Z328R (trembl)


A7K8T9_9PHYC Uncharacterized protein z329L (trembl)


A7K8U9_9PHYC Uncharacterized protein Z339L (trembl)


A7K8W5_9PHYC Uncharacterized protein z355R (trembl)


A7K8W6_9PHYC Uncharacterized protein Z356L (trembl)


A7K8W8_9PHYC Uncharacterized protein Z358R (trembl)


A7K8X4_9PHYC Uncharacterized protein z364L (trembl)


A7K8X5_9PHYC Uncharacterized protein Z365R (trembl)


A7K8X8_9PHYC Uncharacterized protein Z368R (trembl)


A7K8Y0_9PHYC Uncharacterized protein z370L (trembl)


A7K8Y2_9PHYC Uncharacterized protein Z372R (trembl)


A7K8Y4_9PHYC Uncharacterized protein Z374R (trembl)


RNA nuclease activity

Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


chitin binding

Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.


defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.


defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.


defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.


A7K8Y8_9PHYC Uncharacterized protein Z378L (trembl)


A7K8Z7_9PHYC Uncharacterized protein Z387R (trembl)


A7K8Z8_9PHYC Uncharacterized protein z388L (trembl)


A7K901_9PHYC Uncharacterized protein Z391R (trembl)


A7K903_9PHYC Uncharacterized protein Z393R (trembl)


A7K907_9PHYC Uncharacterized protein z397L (trembl)


A7K910_9PHYC Uncharacterized protein z400R (trembl)


A7K915_9PHYC Uncharacterized protein Z405L (trembl)


A7K917_9PHYC Uncharacterized protein Z407L (trembl)


A7K919_9PHYC Uncharacterized protein Z409L (trembl)


A7K926_9PHYC Uncharacterized protein Z416L (trembl)


A7K927_9PHYC Uncharacterized protein Z417L (trembl)


A7K929_9PHYC Uncharacterized protein z419L (trembl)


A7K931_9PHYC Uncharacterized protein Z421L (trembl)


carbon-carbon lyase activity

Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.


pyridoxal phosphate binding

Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.


carboxylic acid metabolic process

The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).


A7K935_9PHYC Uncharacterized protein Z425R (trembl)


A7K940_9PHYC Uncharacterized protein Z430L (trembl)


A7K955_9PHYC Uncharacterized protein z445R (trembl)


A7K956_9PHYC Uncharacterized protein z446R (trembl)


A7K958_9PHYC Uncharacterized protein z448L (trembl)


A7K962_9PHYC Uncharacterized protein Z452R (trembl)


A7K966_9PHYC Uncharacterized protein z456L (trembl)


A7K967_9PHYC Uncharacterized protein Z457L (trembl)


deoxynucleoside kinase activity

Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.


A7K969_9PHYC Uncharacterized protein Z459L (trembl)


A7K979_9PHYC Uncharacterized protein Z469L (trembl)


A7K984_9PHYC Uncharacterized protein Z474R (trembl)


A7K991_9PHYC Uncharacterized protein Z481L (trembl)


A7K999_9PHYC Uncharacterized protein Z489L (trembl)


A7K9B0_9PHYC dUTP diphosphatase (trembl)


dUTP diphosphatase activity

Catalysis of the reaction: dUTP + H2O = dUMP + H+ + diphosphate.


dUMP biosynthetic process

The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).


dUTP catabolic process

The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.


A7K9B2_9PHYC Uncharacterized protein Z502R (trembl)


A7K9B6_9PHYC Uncharacterized protein Z506L (trembl)


A7K9B9_9PHYC Uncharacterized protein Z509L (trembl)


A7K9C1_9PHYC Uncharacterized protein Z511L (trembl)


A7K9C7_9PHYC Uncharacterized protein Z517R (trembl)


A7K9C9_9PHYC Uncharacterized protein z519L (trembl)


A7K9D3_9PHYC Uncharacterized protein Z523L (trembl)


A7K9D7_9PHYC Uncharacterized protein z527L (trembl)


A7K9E0_9PHYC Uncharacterized protein Z530L (trembl)


A7K9E3_9PHYC Uncharacterized protein Z533L (trembl)


A7K9F4_9PHYC Uncharacterized protein Z544R (trembl)


A7K9F8_9PHYC Uncharacterized protein Z548L (trembl)


A7K9F9_9PHYC Uncharacterized protein z549R (trembl)


A7K9G0_9PHYC Uncharacterized protein z550R (trembl)


A7K9G1_9PHYC DNA topoisomerase 2 (trembl)


A7K9G4_9PHYC Uncharacterized protein z554R (trembl)


A7K9G8_9PHYC Uncharacterized protein Z558L (trembl)


A7K9H1_9PHYC Uncharacterized protein Z561L (trembl)


A7K9H3_9PHYC Uncharacterized protein z563R (trembl)


A7K9I0_9PHYC Uncharacterized protein z570L (trembl)


A7K9I1_9PHYC UDP-glucose 6-dehydrogenase (trembl)


UDP-glucose 6-dehydrogenase activity

Catalysis of the reaction: H2O + 2 NAD+ + UDP-alpha-D-glucose = 3 H+ + 2 NADH + UDP-alpha-D-glucuronate.


polysaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


UDP-glucuronate biosynthetic process

The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.


A7K9I5_9PHYC Uncharacterized protein Z575R (trembl)


A7K9I6_9PHYC Uncharacterized protein Z576R (trembl)


A7K9J3_9PHYC Uncharacterized protein z583R (trembl)


A7K9J5_9PHYC Uncharacterized protein Z585R (trembl)


A7K9K0_9PHYC Uncharacterized protein Z590L (trembl)


A7K9K3_9PHYC Uncharacterized protein z593R (trembl)


A7K9K6_9PHYC Uncharacterized protein Z596R (trembl)


A7K9L0_9PHYC Uncharacterized protein z600L (trembl)


A7K9L5_9PHYC Uncharacterized protein Z605R (trembl)


A7K9L8_9PHYC Uncharacterized protein z608L (trembl)


A7K9L9_9PHYC Uncharacterized protein Z609R (trembl)


A7K9M2_9PHYC Uncharacterized protein Z612R (trembl)


A7K9M6_9PHYC Uncharacterized protein Z616L (trembl)


dCMP deaminase activity

Catalysis of the reaction: dCMP + H2O = dUMP + NH3.


pyrimidine nucleotide metabolic process

The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


A7K9M7_9PHYC Uncharacterized protein z617L (trembl)


A7K9M9_9PHYC Uncharacterized protein Z619L (trembl)


A7K9N0_9PHYC Uncharacterized protein z620R (trembl)


A7K9N4_9PHYC Uncharacterized protein z624R (trembl)


A7K9N5_9PHYC Uncharacterized protein Z625L (trembl)


A7K9N9_9PHYC Uncharacterized protein Z629R (trembl)


A7K9P1_9PHYC Uncharacterized protein z631R (trembl)


A7K9P3_9PHYC Uncharacterized protein Z633L (trembl)


A7K9P5_9PHYC Uncharacterized protein z635R (trembl)


A7K9P7_9PHYC Uncharacterized protein Z637L (trembl)


A7K9P9_9PHYC Uncharacterized protein z639R (trembl)


A7K9Q0_9PHYC Uncharacterized protein Z640R (trembl)


A7K9Q1_9PHYC Uncharacterized protein Z641L (trembl)


A7K9Q3_9PHYC Uncharacterized protein Z643L (trembl)


A7K9Q4_9PHYC Uncharacterized protein z644R (trembl)


A7K9Q8_9PHYC Uncharacterized protein z648L (trembl)


A7K9R7_9PHYC Uncharacterized protein z657R (trembl)


A7K9R9_9PHYC Uncharacterized protein z659R (trembl)


A7K9S1_9PHYC Uncharacterized protein Z661L (trembl)


A7K9S2_9PHYC Uncharacterized protein z662L (trembl)


A7K9S3_9PHYC Uncharacterized protein Z663R (trembl)


A7K9S4_9PHYC Uncharacterized protein Z664R (trembl)


A7K9S9_9PHYC Uncharacterized protein Z669L (trembl)


outer membrane

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.


A7K9T0_9PHYC Uncharacterized protein z670R (trembl)


A7K9T6_9PHYC Uncharacterized protein Z676R (trembl)


A7K9T9_9PHYC Uncharacterized protein Z679L (trembl)


translational elongation

The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.


A7K9U4_9PHYC Uncharacterized protein z684R (trembl)


A7K9U8_9PHYC Uncharacterized protein z688R (trembl)


A7K9U9_9PHYC Uncharacterized protein Z689R (trembl)


A7K9V0_9PHYC Uncharacterized protein z690L (trembl)


A7K9V1_9PHYC Uncharacterized protein z691R (trembl)


A7K9V5_9PHYC Uncharacterized protein z695R (trembl)


A7K9V6_9PHYC Uncharacterized protein Z696R (trembl)


potassium ion transmembrane transporter activity

Enables the transfer of potassium ions (K+) from one side of a membrane to the other.


monoatomic ion transport

The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom.


potassium ion transport

The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


potassium ion transmembrane transport

A process in which a potassium ion is transported from one side of a membrane to the other.


A7K9W7_9PHYC Uncharacterized protein Z707L (trembl)


A7K9W8_9PHYC Uncharacterized protein Z708L (trembl)


A7K9X6_9PHYC Uncharacterized protein Z716R (trembl)


A7K9X7_9PHYC Uncharacterized protein Z717R (trembl)


A7K9X9_9PHYC mRNA guanylyltransferase (trembl)


A7K9Y3_9PHYC Uncharacterized protein Z723R (trembl)


A7K9Y4_9PHYC Uncharacterized protein Z724R (trembl)


A7K9Y6_9PHYC Uncharacterized protein z726R (trembl)


A7K9Y8_9PHYC tRNA(Ile)-lysidine synthetase (trembl)


ligase activity, forming carbon-nitrogen bonds

Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.


tRNA processing

The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.


A7KA00_9PHYC Uncharacterized protein Z740R (trembl)


A7KA04_9PHYC Uncharacterized protein Z744R (trembl)


A7KA05_9PHYC Uncharacterized protein Z745R (trembl)


A7KA10_9PHYC Uncharacterized protein Z750R (trembl)


A7KA12_9PHYC Uncharacterized protein Z752L (trembl)


polysaccharide metabolic process

The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


A7KA20_9PHYC Uncharacterized protein Z760R (trembl)


polyamine biosynthetic process

The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.


A7KA23_9PHYC Uncharacterized protein z763L (trembl)


A7KA24_9PHYC Uncharacterized protein z764L (trembl)


A7KA27_9PHYC Uncharacterized protein Z767L (trembl)


A7KA28_9PHYC Uncharacterized protein z768R (trembl)


A7KA33_9PHYC Uncharacterized protein Z773L (trembl)


A7KA37_9PHYC Uncharacterized protein z777R (trembl)


A7KA40_9PHYC Uncharacterized protein Z780L (trembl)


A7KA43_9PHYC Uncharacterized protein z783R (trembl)


A7KA45_9PHYC Uncharacterized protein Z785L (trembl)


A7KA46_9PHYC Uncharacterized protein Z786R (trembl)


A7KA48_9PHYC Uncharacterized protein Z788R (trembl)


A7KA64_9PHYC GDP-mannose 4,6-dehydratase (trembl)


GDP-mannose 4,6-dehydratase activity

Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H2O.


GDP-mannose metabolic process

The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.


A7KA66_9PHYC Uncharacterized protein Z806R (trembl)


protein-arginine deiminase activity

Catalysis of the reaction: H2O + L-arginyl-[protein] = L-citrullyl-[protein] + NH4+, resulting in citrullination of the target protein. This reaction is calcium-dependent.


agmatine deiminase activity

Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.


putrescine biosynthetic process

The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.


A7KA73_9PHYC Uncharacterized protein Z813L (trembl)


A7KA74_9PHYC Uncharacterized protein Z814L (trembl)


hydrolase activity, hydrolyzing O-glycosyl compounds

Catalysis of the hydrolysis of any O-glycosyl bond.


polysaccharide binding

Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.


A7KA78_9PHYC Uncharacterized protein Z818L (trembl)


thymidylate synthase (FAD) activity

Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.


A7KA79_9PHYC Uncharacterized protein Z819L (trembl)


A7KA81_9PHYC Uncharacterized protein z821R (trembl)


A7KA83_9PHYC Uncharacterized protein Z823R (trembl)


A7KA98_9PHYC ribonucleoside-triphosphate reductase (thioredoxin) (trembl)


Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.


cobalamin binding

Binding to cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.


A7KAA1_9PHYC Uncharacterized protein z841R (trembl)


A7KAA9_9PHYC Uncharacterized protein Z849R (trembl)


A7KAB0_9PHYC Uncharacterized protein z850L (trembl)


L7P648_9CIRC Replication-associated protein (trembl)


M1JD72_9VIRU Nonstructural replication protein-like protein (trembl)


K7X4M6_9MONO Fusion glycoprotein F0 (trembl)


fusion of virus membrane with host plasma membrane

Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.


virion membrane

The lipid bilayer surrounding a virion.


K7XAQ7_9MONO Non-structural protein V (trembl)


suppression by virus of host type I interferon-mediated signaling pathway

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity

Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.


modulation by symbiont of host process

The process in which a symbiont organism effects a change in the structure or processes of its host organism.


K7XAQ9_9MONO RNA-directed RNA polymerase L (trembl)


structural constituent of virion

The action of a molecule that contributes to the structural integrity of a virion.


virion assembly

A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.


K7Y0L4_9MONO Attachment protein (trembl)


exo-alpha-sialidase activity

Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.


host cell surface receptor binding

Binding to a receptor on the host cell surface.


viral life cycle

A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.


virion attachment to host cell

The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.


K7X4M8_9MONO Non-structural protein V (trembl)


K7X4N2_9MONO RNA-directed RNA polymerase L (trembl)


K7XBE1_9MONO Attachment protein (trembl)


K7XN73_9MONO Fusion glycoprotein F0 (trembl)


Q91UI8_9VIRU RNA silencing suppressor (trembl)


Q91UJ0_9VIRU Movement protein TGBp3 (trembl)


Q91UJ1_9VIRU Movement protein TGB2 (trembl)


A0A0U3TCD6_9VIRU Nucleocapsid protein (trembl)


A0A0U4CCN7_9VIRU RNA-directed RNA polymerase L (trembl)


A0A223A3I0_9CLOS Putative coat protein (trembl)


A0A223A3Q7_9CLOS Putative 58 kDa protein (Fragment) (trembl)


A0A223A460_9CLOS Putative transmembrane protein (trembl)


A0A223A4D7_9CLOS Putative thaumatin-like protein (trembl)


A0A223A549_9CLOS Heat shock protein 70-like protein (trembl)


G8H9D4_9VIRU Putative replicase (trembl)


A0A6G5X254_9VIRU RNA-directed RNA polymerase L (trembl)


A0A6G5X2C3_9VIRU Uncharacterized protein (trembl)


POLS_ABPVR Structural polyprotein (sprot)


POLN_ABPVR Replicase polyprotein (sprot)


K4HHN2_ARV Non-structural transmembrane glycoprotein (trembl)


endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.


host cell endomembrane system

A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.


K4HIF6_ARV Virion transmembrane glycoprotein (trembl)


A0A0A7W5B8_9POLY Large T antigen (trembl)


suppression by virus of host innate immune response

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense.


disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity

Any process in which interferes with a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1).


modulation by virus of host G1/S transition checkpoint

Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint.


modulation by virus of host cell cycle

Any viral process that modulates the rate or extent of progression through the cell cycle.


A0A0A7W5I1_9POLY Minor capsid protein (trembl)


A0A0A7W722_9POLY Minor capsid protein VP2 (trembl)


ribonucleoside triphosphate phosphatase activity

Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.


AAP_AAV2S Assembly activating protein AAP (sprot)


host cell nucleolus

A small, dense body one or more of which are present in the nucleus of eukaryotic host cells.


protein binding

Binding to a protein.


suppression by virus of G2/M transition of host mitotic cell cycle

Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle.


permeabilization of host organelle membrane involved in viral entry into host cell

Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.


viral entry via permeabilization of inner membrane

The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane.


endocytosis involved in viral entry into host cell

Any endocytosis that is involved in the uptake of a virus into a host cell.


clathrin-dependent endocytosis of virus by host cell

Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.


A0A1J1DNU3_9TOMB Capsid protein (trembl)


T=3 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.


A0A1J1DWM6_9TOMB RNA-directed RNA polymerase (trembl)


A0A916KNR7_9POXV Uncharacterized protein (trembl)


A0A916KNR8_9POXV Uncharacterized protein (trembl)


A0A916KNT8_9POXV RING-type domain-containing protein (trembl)


A0A916KNU6_9POXV Thymidine kinase (trembl)


A0A916KNV3_9POXV VLTF-2 late transcription factor 2 (trembl)


A0A916KNV7_9POXV Ribonucleoside-diphosphate reductase small chain (trembl)


A0A916KNV8_9POXV Uncharacterized protein (trembl)


A0A916KNW2_9POXV DNA polymerase (trembl)


A0A916KNW7_9POXV Poly(A) polymerase catalytic subunit (trembl)


A0A916KNX6_9POXV mRNA decapping enzyme (Cop-D9R) (trembl)


A0A916KNY5_9POXV Uncharacterized protein (trembl)


A0A916KNY7_9POXV DNA topoisomerase (trembl)


A0A916KNY8_9POXV Entry-fusion complex protein OPG086 (trembl)


membrane fusion involved in viral entry into host cell

Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell.


A0A916KNZ0_9POXV Protein tyrosine phosphatase 2 (trembl)


A0A916KNZ1_9POXV Early transcription factor 82 kDa subunit (trembl)


positive regulation of DNA-templated transcription

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.


A0A916KNZ4_9POXV Uncharacterized protein (trembl)


A0A916KNZ5_9POXV DNA-directed RNA polymerase (trembl)


A0A916KP00_9POXV Uncharacterized protein (trembl)


A0A916KP01_9POXV RNA helicase NPH-II (trembl)


A0A916KP05_9POXV Ser/thr kinase (Cop-B1R) (trembl)


A0A916KP12_9POXV Protein phosphatase 1B (trembl)


cation binding

Binding to a cation, a charged atom or group of atoms with a net positive charge.


A0A916KP14_9POXV Entry-fusion complex component, myristylprotein (trembl)


A0A916KP16_9POXV Uncharacterized protein (trembl)


A0A916KP27_9POXV Phospholipase A2-like domain-containing protein (trembl)


phospholipase A2 activity

Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.


phospholipid metabolic process

The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.


arachidonic acid secretion

The controlled release of arachidonic acid from a cell or a tissue.


A0A916KP28_9POXV Sensor histidine kinase (trembl)


A0A916KP29_9POXV 62 kDa protein (trembl)


response to antibiotic

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.


A0A916KP31_9POXV Inhibitor of apoptosis 4 (trembl)


A0A916KP38_9POXV IMV MP/virus entry (Cop-A28L) (trembl)


A0A916KP40_9POXV Uncharacterized protein (trembl)


A0A916KP42_9POXV Entry and fusion IMV protein (Cop-L5R) (trembl)


A0A916KP45_9POXV Probable AP endonuclease (trembl)


A0A916KP48_9POXV Uncharacterized protein (trembl)


A0A916KP54_9POXV Leucine rich repeat gene family (trembl)


A0A916KP56_9POXV mRNA-capping enzyme catalytic subunit (trembl)


A0A916KP57_9POXV Viral late gene transcription factor 3 (trembl)


A0A916KP58_9POXV Uncharacterized protein (trembl)


A0A916KP59_9POXV Virion core protein 4b (trembl)


A0A916KP60_9POXV Late 16kDa membrane protein (Cop-J5L) (trembl)


A0A916KP61_9POXV glycylpeptide N-tetradecanoyltransferase (trembl)


A0A916KP62_9POXV RING-type domain-containing protein (trembl)


A0A916KP65_9POXV Uncharacterized protein (trembl)


A0A916KP66_9POXV Uncharacterized protein (trembl)


A0A916KP69_9POXV IMV membrane protein entry/fusion complex component (Cop-A21L) (trembl)


calcium ion binding

Binding to a calcium ion (Ca2+).


A0A916KP74_9POXV Viral membrane associated, early morphogenesis protein (Cop-A9L) (trembl)


A0A916KP75_9POXV P35 apoptosis inhibitor (trembl)


cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.


negative regulation of apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.


A0A916KP77_9POXV Uncharacterized protein (trembl)


A0A916KP78_9POXV Holliday junction resolvase (trembl)


A0A916KP80_9POXV DNA-directed RNA polymerase 147 kDa polypeptide (trembl)


A0A916KP88_9POXV Uncharacterized protein (trembl)


A0A916KP91_9POXV Virion core cysteine protease (trembl)


A0A916KP92_9POXV Uncharacterized protein (trembl)


A0A916KP98_9POXV Methyltransferase domain-containing protein (trembl)


A0A916KPA4_9POXV N1R/p28-like protein (trembl)


A0A916KPA7_9POXV Cu/Zn superoxide dismutase (trembl)


A0A916KPB2_9POXV Protein phosphatase 2C (trembl)


A0A916KPB5_9POXV Uncharacterized protein (trembl)


A0A916KPB7_9POXV Uncharacterized protein (trembl)


A0A916KPC0_9POXV Uncharacterized protein (trembl)


A0A916KPC5_9POXV Uncharacterized protein (trembl)


A0A916KPD1_9POXV RNA polymerase-associated transcription-specificity factor RAP94 (trembl)


DNA-templated transcription termination

The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.


A0A916KPE1_9POXV Metalloprotease (Cop-G1L) (trembl)


A0A916KPG9_9POXV Myristylated protein, essential for entry/fusion (Cop-A16L) (trembl)


A0A916KPI1_9POXV Uncharacterized protein (trembl)


A0A916KPK6_9POXV Uncharacterized protein (trembl)


A0A916KPL3_9POXV Morph, VETF-s early transcription factor small (trembl)


A0A916KPM7_9POXV Uncharacterized protein (trembl)


A0A916KPN5_9POXV Uncharacterized protein (trembl)


A0A916NWN9_9POXV Early transcription factor 70 kDa subunit (trembl)


A0A916NWQ0_9POXV Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (trembl)


translation elongation factor activity

Functions in chain elongation during polypeptide synthesis at the ribosome.


Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.


regulation of mRNA 3'-end processing

Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.


A0A916NWS5_9POXV Cell division protein FtsL (trembl)


A0A916NWU2_9POXV Uncharacterized protein (trembl)


A0A916NWV6_9POXV Poly(A) polymerase small subunit VP39 (trembl)


A0A916NWW2_9POXV Uncharacterized protein (trembl)


A0A916NWY4_9POXV Uncharacterized protein (trembl)


A0A916NX03_9POXV Uncharacterized protein (trembl)


A0A916NX23_9POXV S-S bond formation pathway protein substrate (Cop-F9L) (trembl)


A0A916NX88_9POXV N1R/p28-like protein (trembl)


A0A916NXD0_9POXV P35 apoptosis inhibitor (trembl)


A0A916P041_9POXV G-protein coupled receptors family 2 profile 2 domain-containing protein (trembl)


transmembrane signaling receptor activity

Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


cell surface receptor signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.


A0A916P060_9POXV Uncharacterized protein (trembl)


A0A916P069_9POXV Uncharacterized protein (trembl)


A0A916P091_9POXV dUTPase-like domain-containing protein (trembl)


A0A916P0A8_9POXV IMV membrane protein (Cop-L1R) (trembl)


A0A916P0B4_9POXV Nucleoside triphosphatase I (trembl)


A0A916P0M3_9POXV Uncharacterized protein (trembl)


A0A916P0P8_9POXV Uracil-DNA glycosylase, DNA polymerase processivity factor (trembl)


A0A916P0Q7_9POXV IMV heparin binding surface protein (trembl)


A0A916P0R3_9POXV Uncharacterized protein (trembl)


A0A916P0U8_9POXV Sulfhydryl oxidase FAD-linked (Cop-E10R) (trembl)


A0A916P0V5_9POXV Uncharacterized protein (trembl)


A0A916P0Y0_9POXV NAD-dependent DNA ligase (trembl)


A0A916P100_9POXV Serine/threonine-protein kinase 2 (trembl)


A0A916P625_9POXV Peptidase M10 metallopeptidase domain-containing protein (trembl)


A0A916P648_9POXV Uncharacterized protein (trembl)


A0A916P676_9POXV Uncharacterized protein (trembl)


A0A916P683_9POXV Uncharacterized protein (trembl)


A0A916P690_9POXV Uncharacterized protein (trembl)


A0A916P6A5_9POXV Entry-fusion complex essential component (Cop-H2R) (trembl)


Q80LH2_NPVAH Late expression factor 1 (trembl)


DNA primase activity

Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.


DNA replication, synthesis of RNA primer

The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis.


Q80LH3_NPVAH Uncharacterized protein (trembl)


Q80LH4_NPVAH Ecdysteroid UDP-glucosyltransferase (trembl)


UDP-glycosyltransferase activity

Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.


Q80LH7_NPVAH Uncharacterized protein (trembl)


Q80LI4_NPVAH Fibroblast growth factor (trembl)


Q80LI5_NPVAH Uncharacterized protein (trembl)


Q80LI7_NPVAH Poly (ADP-ribose) glycohydrolase (PARG) catalytic domain-containing protein (trembl)


Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.


regulation of DNA repair

Any process that modulates the frequency, rate or extent of DNA repair.


Q80LJ0_NPVAH Superoxide dismutase (trembl)


Q80LJ2_NPVAH Calyx/polyhedral envelope protein (trembl)


Q80LJ4_NPVAH Capsid protein P24 (trembl)


Q80LJ6_NPVAH Late expression factor 2 (trembl)


viral transcription

The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.


Q80LJ8_NPVAH Protein kinase interacting protein (trembl)


Q80LK1_NPVAH Per os infectivity factor 2 (trembl)


Q80LK3_NPVAH Uncharacterized protein (trembl)


Q80LK6_NPVAH Uncharacterized protein (trembl)


Q80LL5_NPVAH Uncharacterized protein (trembl)


Q80LL6_NPVAH Capsid protein P80 (trembl)


Q80LM0_NPVAH Basic DNA-binding protein P6.9 (trembl)


Q80LM1_NPVAH Late expression factor 5 (trembl)


Q80LM3_NPVAH Uncharacterized protein (trembl)


Q80LM5_NPVAH Occlusion-derived virus envelope protein E25 (trembl)


Q80LM8_NPVAH Late expression factor 4 (trembl)


Q80LM9_NPVAH Major capsid protein VP39 (trembl)


Q80LN0_NPVAH Capsid associated protein VP91 (trembl)


Q80LN5_NPVAH Very late factor 1 (trembl)


Q80LN8_NPVAH DNA-directed DNA polymerase (trembl)


Q80LP0_NPVAH Late expression factor 3 (trembl)


Q80LP2_NPVAH RrmJ-type SAM-dependent 2'-O-MTase domain-containing protein (trembl)


Q80LP6_NPVAH Occlusion-derived virus envelope protein E66 (trembl)


Q80LP7_NPVAH DNA-directed RNA polymerase (trembl)


Q80LP8_NPVAH J domain-containing protein (trembl)


Q80LR1_NPVAH Late expression factor 9 (trembl)


viral occlusion body

A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host.


2',3'-cyclic GMP-AMP binding

Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.


Q80LR9_NPVAH Envelope protein P74 (trembl)


Q80LS3_NPVAH Occlusion-derived virus envelope protein E18 (trembl)


Q80LS5_NPVAH Chitin-binding type-2 domain-containing protein (trembl)


LEF11_NPVAH Late expression factor 11 (sprot)


Q80LT8_NPVAH Occlusion-derived virus envelope protein E56 (trembl)


Q80LU4_NPVAH Alkaline exonuclease (trembl)


Q77IS9_GVAO Ecdysteroid UDP-glucosyltransferase (trembl)


Q7T9Q5_GVAO Late expression factor 8 (trembl)


telomere maintenance

Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.


Q7T9R5_GVAO Late expression factor 9 (trembl)


Q7T9S1_GVAO DNA-directed DNA polymerase (trembl)


Q7T9S4_GVAO Very late expression factor 1 (trembl)


Q7T9T5_GVAO Late expression factor 4 (trembl)


Q7T9U2_GVAO Late expression factor 5 (trembl)


Q7T9W5_GVAO Late expression factor 11 (trembl)


extracellular matrix

A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.


Q7T9Z8_GVAO Polyhedral envelope protein-p10 (trembl)


Q7TA07_GVAO Chitin-binding protein 1 (trembl)


CAPSD_AADNV Capsid protein VP1/VP2 (sprot)


A0A2Z4GIN2_9MONO RNA-directed RNA polymerase (trembl)


A0A1Z2RT16_9VIRU Uncharacterized protein (trembl)


A0A1Z2RT28_9VIRU Virion glycoprotein N-terminal domain-containing protein (trembl)


A0A1Z2RT29_9VIRU Uncharacterized protein (trembl)


A0A1Z2RT07_9VIRU Putative major core protein (trembl)


VP6_APRVF Microtubule-associated protein VP6 (sprot)


viral inner capsid

The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions.


host cytoskeleton

A cellular structure that forms the internal framework of eukaryotic and prokaryotic host cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.


VP5_APRVF Outer capsid protein VP5 (sprot)


viral outer capsid

The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions.


CAPSD_APRVF Putative major capsid protein VP3 (sprot)


T=2 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.


RDRP_APRVF RNA-directed RNA polymerase VP2 (sprot)


VP1_APRVF Putative structural protein VP1 (sprot)


D4QF72_APBV1 Major virion protein (trembl)


D4QF73_APBV1 Minor virion protein (trembl)


D4QF74_APBV1 Minor virion protein (trembl)


D4QF78_APBV1 Uncharacterized protein (trembl)


host cell junction

A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.


host cell plasmodesma

A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.


A0A1S6PCS2_9VIRU Readthrough protein (trembl)


serine-type exopeptidase activity

Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).


T2FEJ9_9POLY Minor capsid protein VP2 (trembl)


T2FFC5_9POLY Major capsid protein VP1 (trembl)


T2FFJ0_9POLY Minor capsid protein (trembl)


A0A0B5GDD0_9REOV Non-structural protein NS2 (trembl)


A0A0B5GGK4_9REOV Core protein VP4 (trembl)


A0A0B5GPD2_9REOV RNA-directed RNA polymerase (trembl)


A0A0B5GT51_9REOV Outer capsid protein VP2 (trembl)


B1PJ62_9REOV Membrane bound protein (trembl)


B4UUP0_9REOV Outer capsid protein VP5 (trembl)


adhesion of symbiont to host cell

The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.


W5ZZ53_9REOV Inner capsid protein (trembl)


A0A0N7CYV9_AHSV1 Outer capsid protein VP5 (trembl)


A0A0S1NJ35_AHSV1 RNA-directed RNA polymerase (trembl)


A7WPQ7_AHSV1 Non-structural protein NS2 (trembl)


C3TUN5_AHSV1 Outer capsid protein VP2 (trembl)


C1BEG0_9VIRU Movement protein TGB2 (trembl)


C1BEG1_9VIRU Movement protein TGBp3 (trembl)


Q8UZK2_9VIRU RNA-dependent RNA polymerase (trembl)


A0A0B5JFR5_9NIDO GP3 envelope protein (trembl)


A0A0B5JKI0_9NIDO GP4 glycoprotein (trembl)


A0A0B5JQL0_9NIDO GP5 glycosylated envelope protein (trembl)


A0A0B5JQL5_9NIDO Replicase polyprotein 1ab (trembl)


host cell perinuclear region of cytoplasm

The host cell cytoplasm situated near, or occurring around, the host nucleus.


A0A0B5JWP0_9NIDO GP2 glycosylated envelope protein (trembl)


A0A0B5JWP6_9NIDO Envelope protein M (trembl)


148R_ASFB7 Uncharacterized membrane protein EP148R (sprot)


PNG3_ASFB7 Uncharacterized membrane protein pNG3 (sprot)


PNG4_ASFB7 Uncharacterized membrane protein pNG4 (sprot)


PNG6_ASFB7 Uncharacterized membrane protein pNG6 (sprot)


host cell endoplasmic reticulum-Golgi intermediate compartment

A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.


host cell cytosol

The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.


taxis

The directed movement of a motile cell or organism in response to an external stimulus.


P22_ASFB7 Inner membrane protein p22 (sprot)


suppression by virus of host NF-kappaB cascade

Any process in which a virus stops, prevents, or reduces a host NF-kappaB cascade.


I329L_ASFB7 Transmembrane protein I329L (sprot)


suppression by virus of host toll-like receptor signaling pathway

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism.


VF73R_ASFB7 Uncharacterized protein I73R (sprot)


TFIIS_ASFB7 Transcription factor TFIIS homolog (sprot)


UBC_ASFB7 Ubiquitin-conjugating enzyme E2 (sprot)


DIPP_ASFB7 mRNA-decapping protein g5R (sprot)


suppression by virus of host gene expression

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.


host cell rough endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface.


P12_ASFB7 Inner membrane protein p12 (sprot)


cell cycle

The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.


RPB6_ASFB7 DNA-directed RNA polymerase RPB6 homolog (sprot)


ARBH_ASFB7 Apoptosis regulator Bcl-2 homolog (sprot)


suppression by virus of host apoptotic process

Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.


suppression by virus of host autophagy

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host.


modulation by virus of host apoptotic process

Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.


regulation of apoptotic process

Any process that modulates the occurrence or rate of cell death by apoptotic process.


RPB1_ASFB7 DNA-directed RNA polymerase RPB1 homolog (sprot)


DNA-templated viral transcription

A transcription process that uses a viral DNA as a template.


RPB2_ASFB7 DNA-directed RNA polymerase RPB2 homolog (sprot)


RPB10_ASFB7 DNA-directed RNA polymerase RPB10 homolog (sprot)


thymidylate kinase activity

Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.


dTTP biosynthetic process

The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.


The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside.


RIR1_ASFB7 Ribonucleoside-diphosphate reductase large subunit (sprot)


RIR2_ASFB7 Ribonucleoside-diphosphate reductase small chain (sprot)


PK1_ASFB7 Serine/threonine-protein kinase 1 (sprot)


DPOLX_ASFB7 Repair DNA polymerase X (sprot)


VHLP_ASFB7 Viral histone-like protein (sprot)


structural constituent of chromatin

The action of a molecule that contributes to the structural integrity of chromatin.


host cell endoplasmic reticulum lumen

The volume enclosed by the membranes of the host cell endoplasmic reticulum.


IAP_ASFB7 Inhibitor of apoptosis protein (sprot)


induction by virus of host NF-kappaB cascade

Any process in which a virus starts, promotes, or enhances a host NF-kappaB cascade.


VPRT_ASFB7 Cysteine protease S273R (sprot)


VF137_ASFB7 Structural protein A137R (sprot)


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of TBK1 activity

Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of a host serine/threonine kinase TBK1.


VF84_ASFB7 Transmembrane protein EP84R (sprot)


VF421_ASFB7 Uncharacterized protein K421R (sprot)


VF145_ASFB7 Uncharacterized protein K145R (sprot)


viral capsid assembly

The assembly of a virus capsid from its protein subunits.


VF69R_ASFB7 Uncharacterized membrane protein X69R (sprot)


disruption by virus of host JAK-STAT cascade via inhibition of STAT1 activity

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1).


disruption by virus of host JAK-STAT cascade via inhibition of STAT2 activity

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2).


VF118_ASFB7 Uncharacterized protein A118R (sprot)


VF859_ASFB7 Probable helicase A859L (sprot)


VF317_ASFB7 Uncharacterized protein F317L (sprot)


VF165_ASFB7 Uncharacterized protein F165R (sprot)


PRIM_ASFB7 Putative helicase/primase complex protein (sprot)


VF205_ASFB7 Uncharacterized protein K205R (sprot)


induction by virus of host autophagy

Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.


VF424_ASFB7 Probable methyltransferase EP424R (sprot)


VF152_ASFB7 Uncharacterized protein EP152R (sprot)


EP153_ASFB7 Lectin-like protein EP153R (sprot)


VF364_ASFB7 ERCC4 domain-containing protein EP364R (sprot)


response to stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.


M1249_ASFB7 Minor capsid protein M1249L (sprot)


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity

Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.


VF129_ASFB7 Uncharacterized protein C129R (sprot)


VF717_ASFB7 Uncharacterized protein C717R (sprot)


VF122_ASFB7 Uncharacterized protein C122R (sprot)


VF257_ASFB7 Transmembrane protein C257L (sprot)


PAP1_ASFB7 Putative poly(A) polymerase catalytic subunit (sprot)


H962R_ASFB7 Putative primase C962R (sprot)


FLSO_ASFB7 FAD-linked sulfhydryl oxidase (sprot)


dimethylallyltranstransferase activity

Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.


farnesyltranstransferase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.


geranyltranstransferase activity

Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.


geranylfarnesyl diphosphate synthase activity

Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate.


isoprenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.


geranyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of geranyl diphosphate.


geranylgeranyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.


farnesyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.


P49_ASFB7 Minor capsid protein p49 (sprot)


VF169_ASFB7 Transmembrane protein B169L (sprot)


VF475_ASFB7 Uncharacterized protein B475L (sprot)


VF385_ASFB7 Zinc finger protein B385R (sprot)


VF117_ASFB7 Uncharacterized protein B117L (sprot)


VF175_ASFB7 Uncharacterized protein B175L (sprot)


VFB66_ASFB7 Transmembrane protein B66L (sprot)


ETFL_ASFB7 Early transcription factor large subunit homolog (sprot)


VF123_ASFB7 Uncharacterized protein CP123L (sprot)


VF312_ASFB7 Uncharacterized protein CP312R (sprot)


RPB5_ASFB7 DNA-directed RNA polymerase RPB5 homolog (sprot)


RPB3_ASFB7 DNA-directed RNA polymerase RPB3-11 homolog (sprot)


VF171_ASFB7 Uncharacterized protein H171R (sprot)


VF124_ASFB7 Uncharacterized protein H124R (sprot)


VF108_ASFB7 Inner membrane protein H108R (sprot)


CAPSP_ASFB7 Penton protein H240R (sprot)


VF509_ASFB7 Putative ATP-dependent RNA helicase QP509L (sprot)


VF184_ASFB7 Uncharacterized protein E184L (sprot)


P54_ASFB7 Inner membrane protein p54 (sprot)


microtubule-dependent intracellular transport of viral material towards cell periphery

The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.


VF423_ASFB7 Uncharacterized protein E423R (sprot)


VF301_ASFB7 Uncharacterized protein E301R (sprot)


VF146_ASFB7 Uncharacterized protein E146L (sprot)


VF199_ASFB7 Inner membrane protein E199L (sprot)


DUTP_ASFB7 Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


E248R_ASFB7 Inner membrane protein pE248R (sprot)


viral inner membrane

The lipid bilayer of a virion contained inside the protein capsid.


APE_ASFB7 Probable AP endonuclease (sprot)


viral DNA repair

The process of restoring viral DNA after damage or errors in replication.


VFE66_ASFB7 host translation inhibitor E66L (sprot)


modulation by virus of host G0/G1 transition checkpoint

Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint.


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host RIG-I activity

Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.


protein serine/threonine phosphatase inhibitor activity

Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.


suppression by virus of host translation initiation

Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein.


DP96R_ASFB7 TBK1 inhibitor DP96R (sprot)


DP60R_ASFB7 Uncharacterized protein DP60R (sprot)


P17_ASFB7 Minor capsid protein p17 (sprot)


H962L_ASFB7 Putative RNA helicase B962L (sprot)


suppression by virus of host adaptive immune response

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).


ETFS_ASFB7 Early transcription factor large subunit homolog (sprot)


TFNPH_ASFB7 Termination factor NPH-I homolog (sprot)


P10_ASFB7 Structural DNA-binding protein p10 (sprot)


virion nucleoid

The region of a virion in which the nucleic acid is confined.


VF93L_ASFB7 Uncharacterized membrane protein KP93L/DP93R (sprot)


RPB7_ASFB7 DNA-directed RNA polymerase RPB7 homolog (sprot)


A0A1X9ZMU6_9VIRU RNA-dependent RNA polymerase (trembl)


modulation by virus of host process

The process in which a virus effects a change in the structure or processes of its host organism.


negative regulation of gene silencing by regulatory ncRNA

Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.


D1GV13_9GEMI Replication enhancer (trembl)


D1GV14_9GEMI Transcriptional activator protein (trembl)


D1GV15_9GEMI Replication-associated protein (trembl)


E5AZV9_9VIRU Replication associated protein (trembl)


Q8JLM1_9GEMI Transcriptional regulator protein (trembl)


Q8JLM2_9GEMI Replication-associated protein (trembl)


Q8JLM3_9GEMI Transcriptional activator protein (trembl)


Q8JLM4_9GEMI Replication enhancer (trembl)


Q80S64_9GEMI Replication-associated protein (trembl)


Q80S65_9GEMI Transcriptional activator protein (trembl)


Q80S66_9GEMI Replication enhancer (trembl)


RNA-directed DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.


aspartic-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.


RNA-templated DNA biosynthetic process

A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.


B6D5S3_9ABAC Occlusion-derived virus envelope protein ODV-E56 (trembl)


B6D5S5_9ABAC Uncharacterized protein (trembl)


B6D5S6_9ABAC Envelope fusion protein (trembl)


B6D5T1_9ABAC Late expression factor-2 (trembl)


B6D5T2_9ABAC Uncharacterized protein (trembl)


B6D5T8_9ABAC Uncharacterized protein (trembl)


chitinase activity

Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.


chitin catabolic process

The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.


B6D5U5_9ABAC Protein tyrosine phosphatase-2 (trembl)


B6D5U6_9ABAC Ecdysteroid UDP-glucosyltransferase (trembl)


B6D5U9_9ABAC Uncharacterized protein (trembl)


B6D5V2_9ABAC Protein kinase interacting protein-1 (trembl)


B6D5V5_9ABAC Actin rearrangement inducing factor-1 (trembl)


B6D5V6_9ABAC Per os infectivity factor-2 (trembl)


B6D5V7_9ABAC Per os infectivity factor-1 (trembl)


B6D5V9_9ABAC Fibroblast growth factor (trembl)


growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.


signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.


B6D5W0_9ABAC Uncharacterized protein (trembl)


B6D5W1_9ABAC Alkaline exonuclease (trembl)


B6D5W6_9ABAC ribonucleoside-diphosphate reductase (trembl)


B6D5W8_9ABAC Polyhedral envelope protein (trembl)


B6D5X1_9ABAC Superoxide dismutase (trembl)


B6D5X3_9ABAC Per os infectivity factor-3 (trembl)


B6D5X5_9ABAC Poly (ADP-ribose) glycohydrolase (PARG) catalytic domain-containing protein (trembl)


B6D5Y5_9ABAC Occlusion-derived virus envelope protein ODV-E66 (trembl)


B6D5Y6_9ABAC Uncharacterized protein (trembl)


B6D5Y7_9ABAC Occlusion-derived virus envelope protein ODV-EC43 (trembl)


B6D5Z4_9ABAC Late expression factor-5 (trembl)


B6D5Z6_9ABAC Viral enhancing factor-2 (trembl)


B6D5Z9_9ABAC Putative occlusion-derived envelope protein ODV-E28 (trembl)


B6D601_9ABAC Occlusion-derived virus envelope protein ODV-E25 (trembl)


B6D604_9ABAC RING-type domain-containing protein (trembl)


B6D605_9ABAC Late expression factor-4 (trembl)


B6D606_9ABAC Major capsid protein (trembl)


B6D613_9ABAC Very late expression factor-1 (trembl)


B6D616_9ABAC RrmJ-type SAM-dependent 2'-O-MTase domain-containing protein (trembl)


B6D618_9ABAC Late expression factor-3 (trembl)


B6D620_9ABAC DNA-directed DNA polymerase (trembl)


B6D627_9ABAC Late expression factor-9 (trembl)


B6D644_9ABAC DNA-directed RNA polymerase (trembl)


B6D647_9ABAC Occlusion-derived virus envelope protein ODV-E66 (trembl)


B6D652_9ABAC Late expression factor 11 (trembl)


B6D669_9ABAC Chitin-binding type-2 domain-containing protein (trembl)


B6D670_9ABAC Occlusion-derived virus envelope protein ODV-EC27 (trembl)


B6D671_9ABAC Uncharacterized protein (trembl)


B6D672_9ABAC Occlusion-derived virus envelope protein ODV-E18 (trembl)


B6D677_9ABAC Ribonucleoside-diphosphate reductase (trembl)


Q6QXF7_GVAS ribonucleoside-diphosphate reductase (trembl)


Q6QXG1_GVAS DNA-directed DNA polymerase (trembl)


Q6QXI9_GVAS Ecdysteroid UDP-glucosyltransferase (trembl)


Q6QXJ5_GVAS Late expression factor 11 (trembl)


modulation by symbiont of host protein ubiquitination

Any process by which a symbiont increases or decreases ubiquitination of target proteins of a host organism.


A0A220IGE2_9PAPI Replication protein E1 (trembl)


A0A220IGE4_9PAPI Minor capsid protein L2 (trembl)


microtubule-dependent intracellular transport of viral material towards nucleus

The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.


transport of viral material towards nucleus

The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane.


host cell endosome

A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.


A0A220IGE5_9PAPI Regulatory protein E2 (trembl)


A0A220IGF5_9PAPI Major capsid protein L1 (trembl)


T=7 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.


protein domain specific binding

Binding to a specific domain of a protein.


A0A220IGE7_9PAPI Regulatory protein E2 (trembl)


A0A220IGE8_9PAPI Replication protein E1 (trembl)


A0A220IGG0_9PAPI Minor capsid protein L2 (trembl)


A0A220IGG3_9PAPI Major capsid protein L1 (trembl)


A0A0K1RL37_9CIRC Putative replication initiation protein (Fragment) (trembl)


A0A3G6V9C9_9CLOS ORF1a polyprotein (trembl)


A0A0M5L4E9_9VIRU RNA-directed RNA polymerase L (trembl)


endoplasmic reticulum-Golgi intermediate compartment

A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.


A8QZ16_9VIRU Envelopment polyprotein (trembl)


A0A343W7C2_9POLY Large T antigen (trembl)


A0A343W7C3_9POLY Small T antigen (trembl)


A0A068A9W5_9GAMA Envelope glycoprotein B (trembl)


host cell endosome membrane

The lipid bilayer surrounding a host cell endosome.


A0A068A9W6_9GAMA Capsid scaffolding protein (trembl)


viral release from host cell

The dissemination of mature viral particles from a host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.


A0A068A9W7_9GAMA Envelope glycoprotein H (trembl)


A0A068A9W9_9GAMA Cytoplasmic envelopment protein 2 (trembl)


viral tegument

A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.


A0A068A9X0_9GAMA Cytoplasmic envelopment protein 3 (trembl)


viral budding from Golgi membrane

A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.


A0A068A9X1_9GAMA Portal protein (trembl)


A0A068A9X5_9GAMA Triplex capsid protein 1 (trembl)


A0A068A9X6_9GAMA Nuclear egress protein 2 (trembl)


host cell nuclear inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.


intracellular transport of virus

The directed movement of a virus, or part of a virus, within the host cell.


A0A068AAJ8_9GAMA Capsid vertex component 2 (trembl)


viral genome packaging

The encapsulation of the viral genome within the capsid.


A0A068AAK0_9GAMA DNA polymerase (trembl)


A0A068AAK9_9GAMA Tripartite terminase subunit 3 (trembl)


A0A068AAL4_9GAMA Envelope glycoprotein M (trembl)


A0A068AAL7_9GAMA DNA replication helicase (trembl)


bidirectional double-stranded viral DNA replication

A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.


A0A068AAL8_9GAMA Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


dUTP metabolic process

The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.


A0A068AAM4_9GAMA Large tegument protein deneddylase (trembl)


A0A068AAM7_9GAMA Packaging protein UL32 (trembl)


A0A068AAN1_9GAMA Tripartite terminase subunit 2 (trembl)


viral DNA genome packaging

The packing of viral DNA into a capsid.


semaphorin receptor binding

Binding to a semaphorin receptor.


A0A068ABP1_9GAMA Tripartite terminase subunit 1 (trembl)


protein processing

Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.


A0A068ABQ0_9GAMA Thymidine kinase (trembl)


TMP biosynthetic process

The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.


A0A068ABQ3_9GAMA Triplex capsid protein 2 (trembl)


A0A068ABQ7_9GAMA Capsid vertex component 1 (trembl)


A0A068ABR2_9GAMA Shutoff alkaline exonuclease (trembl)


induction by virus of catabolism of host mRNA

The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA).


nucleic acid phosphodiester bond hydrolysis

The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.


A0A068ABR6_9GAMA Cytoplasmic envelopment protein 1 (trembl)


A0A068ABR9_9GAMA Envelope glycoprotein L (trembl)


A0A068ABT4_9GAMA Ribonucleoside-diphosphate reductase large subunit (trembl)


A0A068ADB3_9GAMA Major DNA-binding protein (trembl)


A0A068ADD0_9GAMA Major capsid protein (trembl)


T=16 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres.


A0A068ADF3_9GAMA Uracil-DNA glycosylase (trembl)


A0A068ADH0_9GAMA Ribonucleoside-diphosphate reductase small subunit (trembl)


deoxyribonucleoside diphosphate metabolic process

The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.


A0A068ADH6_9GAMA Small capsomere-interacting protein (trembl)


A0A068ADI3_9GAMA Nuclear egress protein 1 (trembl)


viral budding from nuclear membrane

A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.


exit of virus from host cell nucleus by nuclear egress

The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.


VGA4_ALHV1 Uncharacterized gene A4 protein (sprot)


DNBI_ALHV1 Major DNA-binding protein (sprot)


TRM1_ALHV1 Tripartite terminase subunit 1 (sprot)


GB_ALHV1 Envelope glycoprotein B (sprot)


DPOL_ALHV1 DNA polymerase catalytic subunit (sprot)


VGA5_ALHV1 G-protein coupled receptor A5 (sprot)


G protein-coupled receptor activity

Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


G protein-coupled receptor signaling pathway

The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.


SCAF_ALHV1 Capsid scaffolding protein (sprot)


CVC2_ALHV1 Capsid vertex component 2 (sprot)


GH_ALHV1 Envelope glycoprotein H (sprot)


TRX2_ALHV1 Triplex capsid protein 2 (sprot)


VG27_ALHV1 Uncharacterized gene 27 protein (sprot)


TRM3_ALHV1 Tripartite terminase subunit 3 (sprot)


CVC1_ALHV1 Capsid vertex component 1 (sprot)


CEP2_ALHV1 Cytoplasmic envelopment protein 2 (sprot)


VG36_ALHV1 Putative tyrosine kinase 36 (sprot)


protein tyrosine kinase activity

Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.


non-membrane spanning protein tyrosine kinase activity

Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.


AN_ALHV1 Shutoff alkaline exonuclease (sprot)


CEP3_ALHV1 Cytoplasmic envelopment protein 3 (sprot)


GM_ALHV1 Envelope glycoprotein M (sprot)


VG40_ALHV1 Uncharacterized gene 40 protein (sprot)


CEP1_ALHV1 Cytoplasmic envelopment protein 1 (sprot)


HELI_ALHV1 DNA replication helicase (sprot)


UNG_ALHV1 Uracil-DNA glycosylase (sprot)


GL_ALHV1 Envelope glycoprotein L (sprot)


BRLF1_ALHV1 Putative transcription activator BRLF1 homolog (sprot)


VGA7_ALHV1 Putative C-type lectin protein A7 (sprot)


VGA8_ALHV1 Uncharacterized gene A8 protein (sprot)


GN_ALHV1 Envelope glycoprotein N (sprot)


DUT_ALHV1 Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


TEG7_ALHV1 Tegument protein UL51 homolog (sprot)


IE63_ALHV1 Immediate-early phosphoprotein 57 (sprot)


VG59_ALHV1 DNA polymerase processivity factor (sprot)


RIR2_ALHV1 Ribonucleoside-diphosphate reductase small subunit (sprot)


viral latency

The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.


release from viral latency

The process by which a virus begins to replicate following a latency replication decision (switch).


RIR1_ALHV1 Ribonucleoside-diphosphate reductase large subunit (sprot)


TRX1_ALHV1 Triplex capsid protein 1 (sprot)


ITP_ALHV1 Inner tegument protein (sprot)


LTP_ALHV1 Large tegument protein deneddylase (sprot)


SCP_ALHV1 Small capsomere-interacting protein (sprot)


UL49_ALHV1 Uncharacterized gene 66 protein (sprot)


NEC2_ALHV1 Nuclear egress protein 2 (sprot)


TRM2_ALHV1 Tripartite terminase subunit 2 (sprot)


UL32_ALHV1 Packaging protein UL32 homolog (sprot)


NEC1_ALHV1 Nuclear egress protein 1 (sprot)


VP75_ALHV1 Probable membrane antigen 75 (sprot)


VGA9_ALHV1 Putative apoptosis regulator A9 (sprot)


VGA10_ALHV1 Uncharacterized gene A10 protein (sprot)


VGA2_ALHV1 Uncharacterized protein A2 (sprot)


VP03_ALHV1 Probable tegument protein antigen 3 (sprot)


SEMA_ALHV1 Semaphorin-like protein A3 (sprot)


A0A2Z5CHL8_9VIRU Replication-associated protein (trembl)


A0A2Z5CJA2_9VIRU Replication associated protein (trembl)


A0A2Z5CI32_9VIRU Replication-associated protein (trembl)


A0A2Z5CK60_9VIRU Replication-associated protein (trembl)


A0A0N9M4N8_9VIRU Envelopment polyprotein (trembl)


fusion of virus membrane with host endosome membrane

Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell.


A0A0N9MMM4_9VIRU RNA-directed RNA polymerase L (trembl)


F2W3P2_9VIRU RNA-directed RNA polymerase L (trembl)


F2W3P3_9VIRU Envelopment polyprotein (trembl)


MEM_GOGV Putative membrane protein (sprot)


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity

Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).


L_GOGV RNA-directed RNA polymerase L (sprot)


cap snatching

A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.


viral replication complex

Specific locations and structures in the virus infected cell involved in replicating the viral genome.


NS2_ADVG Non-structural protein NS2 (sprot)


NS3_ADVG Non-structural protein NS3 (sprot)


A0A451G5G8_9RHAB RNA-directed RNA polymerase (trembl)


A0A166J1Q2_9VIRU RNA-dependent RNA polymerase (trembl)


A0A166J1Q3_9VIRU Peptidase S39 domain-containing protein (trembl)


A0A166J1S0_9VIRU Readthrough protein (trembl)


A0A0C5GVW6_9VIRU Capsid protein (trembl)


A0A0C5GWS6_9VIRU Movement protein TGBp3 (trembl)


A0A0C5H7M3_9VIRU RNA-dependent RNA polymerase (trembl)


Q913Z7_9VIRU Movement protein TGB2 (trembl)


A0A0K0PRX7_9GEMI Replication-associated protein (trembl)


A0A0K0PSZ7_9GEMI Replication-associated protein (trembl)


RDRP_AMVLE RNA-directed RNA polymerase 2a (sprot)


positive stranded viral RNA replication

A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.


A0A1X9PY58_9VIRU Movement protein TGBp3 (trembl)


A0A2H5MI89_9VIRU RNA-directed RNA polymerase (trembl)


C0L9E1_9VIRU RNA replication protein (trembl)


C0L9E4_9VIRU Movement protein TGBp3 (trembl)


A0A024A1N5_9RHAB Virion transmembrane glycoprotein G (trembl)


Q65A77_9VIRU RNA-directed RNA polymerase (trembl)


Q65A78_9VIRU Putative coat protein (trembl)


A0A0U1UZ37_9ALPC Spike glycoprotein (trembl)


receptor-mediated virion attachment to host cell

The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.


A0A0U1WHF8_9ALPC Membrane protein (trembl)


A0A0U1WHG4_9ALPC ORF1ab polyprotein (trembl)


3'-5'-RNA exonuclease activity

Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.


RNA exonuclease activity

Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.


omega peptidase activity

Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes.


regulation of autophagy

Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.


A0A0U1WHG6_9ALPC Uncharacterized protein (trembl)


A0A0U1WJX0_9ALPC Small envelope protein (trembl)


pore formation by virus in membrane of host cell

The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism.


A0A166MMH2_9PAPI Regulatory protein E2 (trembl)


PDZ domain binding

Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.


A0A166MNN5_9PAPI Replication protein E1 (trembl)


A0A166MNQ4_9PAPI Minor capsid protein L2 (trembl)


A0A166MNR6_9PAPI Major capsid protein L1 (trembl)


A0A6G9LUF7_9POLY Minor capsid protein VP2 (trembl)


A0A6G9LUG9_9POLY Large T antigen (trembl)


A0A6G9LWU8_9POLY Small T antigen (trembl)


A0A6G9LXA2_9POLY Viral protein 1 (trembl)


L0G8J4_9POLY Major structural protein VP1 (trembl)


L0GAJ8_9POLY Minor capsid protein VP2 (trembl)


L0GCG9_9POLY Minor capsid protein VP2 (trembl)


A0A5J6XVL7_9POLY Middle T antigen (trembl)


K7QJJ1_9POLY Capsid protein VP1 (trembl)


K7QKH3_9POLY Minor capsid protein (trembl)


L0MZS8_9POLY Capsid protein VP1 (trembl)


L0MZU2_9POLY Minor capsid protein (trembl)


L0N1V5_9POLY Minor capsid protein (trembl)


Q3V6G4_9VIRU Movement protein TGBp3 (trembl)


Q3V6G5_9VIRU Triple gene block protein 2 (trembl)


Q3V6G6_9VIRU Triple gene block protein 1 (trembl)


Q3V6G7_9VIRU RNA replication protein (trembl)


Q2TJB0_9VIRU Triple gene block 1 protein 26k (trembl)


Q2TJB1_9VIRU RNA replication protein (trembl)


Q52Z67_9VIRU Movement protein TGBp3 (trembl)


Q4GZI5_9GEMI Replication-associated protein (trembl)


Q4GZI6_9GEMI Transcriptional activator protein (trembl)


Q4GZI7_9GEMI Replication enhancer (trembl)


A0A146HTD0_9VIRU Putative coat protein (trembl)


A0A146HTF4_9VIRU RNA-directed RNA polymerase (trembl)


host cell cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.


A0A076L0Y3_9VIRU RNA-dependent RNA polymerase (trembl)


Q65A75_9VIRU RNA-dependent RNA polymerase (trembl)


Q65A76_9VIRU Putative coat protein (trembl)


I7GUN6_9BROM Replication protein 1a (trembl)


I7HHJ1_9BROM RNA-directed RNA polymerase 2a (trembl)


V5V0U1_9VIRU Putative triple gene block protein 1 (trembl)


V5V1N5_9VIRU Movement protein TGBp3 (trembl)


V5V1R1_9VIRU RNA replication protein (trembl)


V5V1S7_9VIRU Putative triple gene block protein 2 (trembl)


V5V388_9VIRU Putative coat protein (trembl)


U3LXW9_9RHAB RNA-directed RNA polymerase L (trembl)


I1W5T2_9VIRU Putative viral replicase (trembl)


I1W5T3_9VIRU Triple gene block protein 1 (trembl)


I1W5T4_9VIRU Movement protein TGB2 (trembl)


I1W5T5_9VIRU Movement protein TGBp3 (trembl)


I1W5T7_9VIRU RNA silencing suppressor (trembl)


Q997A3_9BROM RNA-directed RNA polymerase 2a (trembl)


Q997A4_9BROM Replication protein 1a (trembl)


A0A1P8YT73_9VIRU Replication associated protein (trembl)


A0A1P8YT80_9VIRU Replication-associated protein (trembl)


NTP1_AMEPV Nucleoside triphosphatase I (sprot)


A28_AMEPV Envelope protein A28 homolog (sprot)


I7_AMEPV Core protease I7 homolog (sprot)


P87507_AMEPV DNA topoisomerase I (trembl)


Q9EMH5_AMEPV Uracil-DNA glycosylase (trembl)


Q9EMI5_AMEPV DNA-directed RNA polymerase 147 kDa polypeptide (trembl)


NMT_AMEPV Putative glycylpeptide N-tetradecanoyltransferase (sprot)


Q9EMJ6_AMEPV Probable AP endonuclease (trembl)


Q9EMK1_AMEPV Viral late gene transcription factor 3 (trembl)


Q9EMP6_AMEPV Serine/threonine-protein kinase (trembl)


Q9EMQ2_AMEPV Virion core protein 4b (trembl)


Q9EMR4_AMEPV mRNA-capping enzyme catalytic subunit (trembl)


ABC-type transporter activity

Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.


Q9EMT4_AMEPV Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (trembl)


Q9EMT5_AMEPV Sulfhydryl oxidase (trembl)


Q9EMU4_AMEPV Early transcription factor 82 kDa subunit (trembl)


Q9EMW8_AMEPV RNA helicase NPH-II (trembl)


PTPH_AMEPV Putative tyrosine-protein phosphatase AMV078 (sprot)


Q9EMX8_AMEPV Entry-fusion complex protein OPG086 (trembl)


Q9EMY3_AMEPV DNA-directed RNA polymerase (trembl)


Q9EMY9_AMEPV Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (trembl)


Q9EMZ5_AMEPV RNA polymerase-associated transcription-specificity factor RAP94 (trembl)


Q9EN10_AMEPV Poly(A) polymerase catalytic subunit (trembl)


Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine.


Q9EN44_AMEPV Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


nicotinamide riboside transmembrane transporter activity

Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.


nicotinamide riboside transport

The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


F1T292_9VIRU Envelopment polyprotein (trembl)


disruption by virus of host TRAF-mediated signal transduction

Any process in which a virus interferes with TRAF-mediated signal transduction in the host.


host cell surface

The external part of the host cell wall and/or host plasma membrane.


F1T293_9VIRU RNA-directed RNA polymerase L (trembl)


A0A076L0K3_9MONO Cysteine-rich protein V (trembl)


A0A076L0K8_9MONO RNA-directed RNA polymerase L (trembl)


A0A076L152_9MONO Hemagglutinin-neuraminidase protein HN (trembl)


A0A076L670_9MONO Matrix protein (trembl)


A0A076L8G4_9MONO Fusion glycoprotein F0 (trembl)


A1YZN4_9ALPH Tegument/envelope protein (trembl)


A1YZN7_9ALPH Tripartite terminase subunit 2 (trembl)


A1YZN8_9ALPH Nuclear egress protein 2 (trembl)


A2TIU6_9ALPH Capsid vertex component 1 (trembl)


A2TIU8_9ALPH Triplex capsid protein 2 (trembl)


A2TIV0_9ALPH Envelope protein UL20 (trembl)


host cell nuclear membrane

Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.


A2TIV6_9ALPH Small capsomere-interacting protein (trembl)


A2TIV8_9ALPH Capsid scaffolding protein (trembl)


A2TIW0_9ALPH Envelope glycoprotein B (trembl)


A3RMA2_9ALPH DNA helicase/primase complex-associated protein (trembl)


A3RMA4_9ALPH Envelope glycoprotein M (trembl)


A3RMA5_9ALPH Envelope glycoprotein L (trembl)


A3RMB2_9ALPH Cytoplasmic envelopment protein 1 (trembl)


A4GRI5_9ALPH Cytoplasmic envelopment protein 2 (trembl)


A4GRJ2_9ALPH Tegument protein UL21 (trembl)


A4GRJ3_9ALPH Envelope glycoprotein H (trembl)


A4GRJ6_9ALPH Capsid vertex component 2 (trembl)


A4GRK2_9ALPH Nuclear egress protein 1 (trembl)


A4GRK3_9ALPH Packaging protein UL32 (trembl)


A4ZX80_9ALPH Tegument protein VP22 (trembl)


A4ZX81_9ALPH Envelope glycoprotein (trembl)


A4ZX82_9ALPH Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


A5A413_9ALPH Tegument serine/threonine protein kinase (trembl)


A5A414_9ALPH Tegument protein UL14 (trembl)


A5A417_9ALPH Regulatory protein US1 (trembl)


regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


A7L873_9ALPH Tegument protein UL51 (trembl)


A9QXU7_9ALPH Envelope glycoprotein K (trembl)


fusion of viral membrane with host outer nuclear membrane

Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.


positive regulation of syncytium formation by virus

The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


host cell nuclear matrix

The dense fibrillar network lying on the inner side of the host nuclear membrane.


B4XS31_9ALPH Envelope glycoprotein D (trembl)


B5LRM7_9ALPH Uracil-DNA glycosylase (trembl)


B6E8Y9_9ALPH Tegument protein UL37 (trembl)


B6E8Z0_9ALPH Triplex capsid protein 1 (trembl)


B6E8Z2_9ALPH Ribonucleoside-diphosphate reductase small subunit (trembl)


deNEDDylase activity

An isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.


C6ZD01_9ALPH DNA polymerase processivity factor (trembl)


C6ZD04_9ALPH Ribonucleoside-diphosphate reductase large subunit (trembl)


C6ZD24_9ALPH Major capsid protein (trembl)


C6ZD35_9ALPH Replication origin-binding protein (trembl)


C6ZD38_9ALPH Envelope glycoprotein E (trembl)


anchoring junction

A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.


E1U2A6_9ALPH Envelope glycoprotein I (trembl)


E1U2B0_9ALPH Multifunctional expression regulator (trembl)


E6Y393_9ALPH DNA replication helicase (trembl)


E6Y394_9ALPH Nuclear protein UL4 (trembl)


E6Y398_9ALPH Tegument protein UL47 (trembl)


E6Y399_9ALPH Alpha trans-inducing protein (trembl)


H9DUZ2_9ALPH Virion host shutoff protein (trembl)


H9DV04_9ALPH Major DNA-binding protein (trembl)


H9DV05_9ALPH Tripartite terminase subunit 1 (trembl)


H9DV17_9ALPH Tripartite terminase subunit 3 (trembl)


L_ANDV RNA-directed RNA polymerase L (sprot)


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity

Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.


A0A088SG43_9GEMI Transcriptional activator protein (trembl)


A0A088SGC3_9GEMI Replication-associated protein (trembl)


A0A088SGJ4_9GEMI Capsid protein (trembl)


A0A088T1G4_9GEMI Replication enhancer (trembl)


A0A140GL60_9VIRU Virion-associated protein (trembl)


A0A140GL62_9VIRU Enzymatic polyprotein (trembl)


A0A140GL63_9VIRU Transactivator/viroplasmin protein (trembl)


Q2Q474_9TOMB RNA-directed RNA polymerase (trembl)


W5RNT1_9CIRC Replication-associated protein (trembl)


H6U321_9VIRU RNA-directed RNA polymerase L (trembl)


H6U322_9VIRU Envelopment polyprotein (trembl)


W6JIK4_9POXV Uncharacterized protein (trembl)


W6JIL4_9POXV Nicotinamide riboside kinase 1 (trembl)


W6JIL6_9POXV Uncharacterized protein (trembl)


W6JIM7_9POXV Putative membrane protein (trembl)


W6JIP4_9POXV Putative calcium binding protein (trembl)


W6JIQ1_9POXV IMV membrane protein (trembl)


W6JIR8_9POXV Putative late transcription factor VLTF-2 (trembl)


W6JIS3_9POXV Protein kinase domain containing protein (trembl)


W6JIS6_9POXV Holliday junction resolvase (trembl)


W6JIS7_9POXV Putative core protein (trembl)


W6JIT4_9POXV Superoxide dismutase (trembl)


W6JIT6_9POXV Putative myristylated membrane protein (trembl)


W6JIT8_9POXV Uncharacterized protein (trembl)


W6JIT9_9POXV Uncharacterized protein (trembl)


W6JIU0_9POXV Tryptophan-rich sensory protein (trembl)


W6JIU3_9POXV Uncharacterized protein (trembl)


W6JIU5_9POXV Precursor p4a of core protein 4a (trembl)


W6JIU6_9POXV Putative glycosyl transferase (trembl)


W6JIU7_9POXV DNA helicase, transcriptional elongation (trembl)


W6JIV1_9POXV Reverse transcriptase (trembl)


W6JIV2_9POXV Serin/threonine kinase like (trembl)


W6JIV8_9POXV Zinc-dependent metalloprotease (trembl)


W6JIW0_9POXV Serine/threonine-protein kinase 2 (trembl)


W6JIW3_9POXV Putative viral membrane protein (trembl)


W6JIW4_9POXV Virion membrane formation (trembl)


W6JIW7_9POXV Triacylglycerol lipase (trembl)


W6JIW8_9POXV Putative NTP pyrophosphohydrolase mutT motif (trembl)


W6JIX0_9POXV Uncharacterized protein (trembl)


W6JIX9_9POXV Uncharacterized protein (trembl)


W6JIY5_9POXV Capcid protein VP1-like (trembl)


W6JIZ0_9POXV S-S bond formation pathway protein (trembl)


W6JIZ4_9POXV Putative glycoprotein B (trembl)


W6JIZ6_9POXV Early transcription factor 82 kDa subunit (trembl)


W6JJ01_9POXV Late transcription factor VLTF-3 (trembl)


W6JJ15_9POXV Probable AP endonuclease (trembl)


W6JJ19_9POXV Uncharacterized protein (trembl)


W6JJ26_9POXV Uncharacterized protein (trembl)


W6JJ39_9POXV Putative exonuclease RNase T and DNA polymerase III (trembl)


W6JKS0_9POXV Matrix metalloproteinase (trembl)


W6JKT0_9POXV Putative ATP-binding cassette transporter (trembl)


W6JKU0_9POXV IMV membrane protein involved in fusion and entry (trembl)


W6JKU5_9POXV Uncharacterized protein (trembl)


W6JKV6_9POXV Uncharacterized protein (trembl)


W6JKY2_9POXV DNA-directed RNA polymerase (trembl)


W6JKY5_9POXV IMV membrane protein (trembl)


W6JKZ1_9POXV Uncharacterized protein (trembl)


W6JKZ5_9POXV Putative early transcription factor small subunit (trembl)


W6JKZ6_9POXV Putative ser/thr protein kinase (trembl)


W6JKZ9_9POXV G-protein coupled receptor Mth2-like (trembl)


W6JL01_9POXV Uncharacterized protein (trembl)


W6JL07_9POXV mRNA-capping enzyme catalytic subunit (trembl)


W6JL13_9POXV RNA polymerase-associated transcription-specificity factor RAP94 (trembl)


W6JL18_9POXV Ubiquitin/ribosomal protein (trembl)


ribosome

An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.


W6JL25_9POXV RNA helicase NPH-II (trembl)


W6JL30_9POXV Putative poly(A) polymerase small subunit (trembl)


W6JL37_9POXV DNA-directed RNA polymerase beta chain (trembl)


W6JL47_9POXV Peritrophin-A domain containing protein (trembl)


W6JL61_9POXV Entry-fusion complex protein OPG086 (trembl)


W6JL64_9POXV DNA-directed RNA polymerase 147 kDa polypeptide (trembl)


W6JL71_9POXV Zinc-dependent metalloprotease (trembl)


W6JL79_9POXV Uncharacterized protein (trembl)


W6JL81_9POXV Uncharacterized protein (trembl)


W6JL83_9POXV Phosphatidic acid phosphatase type 2 (trembl)


W6JLB2_9POXV Poxvirus myristoylprotein (trembl)


W6JLC2_9POXV Putative myristylated membrane protein (trembl)


W6JLD1_9POXV Translation elongation factor eEF-3 like (trembl)


W6JLD5_9POXV Uncharacterized protein (trembl)


W6JLG4_9POXV Putative NAD+ dependent DNA ligase (trembl)


W6JLH1_9POXV Cation transport ATPase (trembl)


W6JLH5_9POXV Uncharacterized protein (trembl)


W6JLI2_9POXV Translation initiation factor elF-4e (trembl)


W6JLI8_9POXV Uncharacterized protein (trembl)


W6JLJ1_9POXV Virion core protein 4b (trembl)


W6JLK0_9POXV Poly(A) polymerase catalytic subunit (trembl)


W6JLK9_9POXV Ubiquitin-conjugating enzyme E2 (trembl)


W6JLL8_9POXV PPM-type phosphatase domain-containing protein (trembl)


W6JLM1_9POXV Uncharacterized protein (trembl)


W6JLM5_9POXV Putative NTPase/helicase (trembl)


W6JLN7_9POXV glycylpeptide N-tetradecanoyltransferase (trembl)


W6JLQ8_9POXV Zinc-dependent metalloprotease (trembl)


W6JPJ3_9POXV Uncharacterized protein (trembl)


W6JPJ7_9POXV Uracil-DNA glycosylase (trembl)


W6JPJ9_9POXV Putative mRNA capping enzyme small subunit (trembl)


W6JPK2_9POXV Uncharacterized protein (trembl)


W6JPK4_9POXV Nucleoside triphosphatase I (trembl)


W6JPK8_9POXV 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (trembl)


W6JPK9_9POXV Uncharacterized protein (trembl)


W6JPL0_9POXV Virion membrane protein (trembl)


W6JPL4_9POXV Endonuclease/exonuclease/phosphatase domain-containing protein (trembl)


W6JPL5_9POXV Uncharacterized protein (trembl)


W6JPL7_9POXV Uncharacterized protein (trembl)


W6JPM1_9POXV Uncharacterized protein (trembl)


W6JPM3_9POXV Uncharacterized protein (trembl)


W6JPM4_9POXV ATP-dependent DNA ligase (trembl)


W6JPM5_9POXV Nucleopolyhedrovirus p26 protein (trembl)


W6JPM6_9POXV Putative vaccinia G1L metaloprotease (trembl)


W6JPM9_9POXV Uncharacterized protein (trembl)


W6JPN2_9POXV Uncharacterized protein (trembl)


W6JPN3_9POXV Uncharacterized protein (trembl)


W6JPN4_9POXV Gamma-glutamyl cyclotransferase like (trembl)


W6JPN8_9POXV Peptidase M10 metallopeptidase domain-containing protein (trembl)


A0A291NVX1_9VIRU Envelopment polyprotein (trembl)


A0A291NVX5_9VIRU RNA-directed RNA polymerase L (trembl)


W8QE04_9VIRU Uncharacterized protein (trembl)


W8QE16_9VIRU DNA-directed RNA polymerase (trembl)


W8QE20_9VIRU Membrane-type matrix metallopeptidase-1 (trembl)


W8QE39_9VIRU Type III restriction enzyme, res subunit:DEAD/DEAH box helicase, N-terminal (trembl)


W8QE45_9VIRU Lipid membrane protein (trembl)


W8QE57_9VIRU ribonucleoside-diphosphate reductase (trembl)


W8QE71_9VIRU RuvC-like Holliday junction resolvase (trembl)


W8QE83_9VIRU 5'-3' exoribonuclease 1 (trembl)


W8QE87_9VIRU Resolvase HTH domain-containing protein (trembl)


W8QEY7_9VIRU C3H1-type domain-containing protein (trembl)


W8QF03_9VIRU Putative tyrosine protein kinase (trembl)


W8QF08_9VIRU Ribonucleoside-diphosphate reductase large subunit (trembl)


W8QF12_9VIRU DNA-directed DNA polymerase (trembl)


W8QF27_9VIRU Transcription factor TFIIB cyclin-like domain-containing protein (trembl)


W8QF41_9VIRU Uncharacterized protein (trembl)


W8QF60_9VIRU DNA ligase (NAD(+)) (trembl)