regulation of hormone biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.


regulation of alkane biosynthetic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that modulates the frequency, rate or extent of alkane biosynthetic process.


regulation of macrophage inflammatory protein 1 alpha production

Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


negative regulation of sulfur amino acid metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.


positive regulation of hexadecanal metabolic process

Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process.


positive regulation of CREB transcription factor activity

Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.


regulation of transcription by RNA polymerase V

Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase V.


negative regulation of interleukin-11 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.


regulation of type III interferon production

Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


regulation of mast cell cytokine production

Any process that modulates the frequency, rate, or extent of mast cell cytokine production.


positive regulation of mitochondrial DNA replication

Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.


negative regulation of transforming growth factor beta2 activation

Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation.


regulation of thiamine biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.


regulation of rRNA stability

Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.


positive regulation of phosphatidate phosphatase activity

Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity.


negative regulation of estrogen biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process.


positive regulation of termination of RNA polymerase II transcription

Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.


positive regulation of tetrapyrrole metabolic process

Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.


positive regulation of nitric oxide biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.


positive regulation of mRNA cis splicing, via spliceosome

Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome.


negative regulation of interleukin-22 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.


regulation of type IV site-specific deoxyribonuclease activity

Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.


regulation of nucleotide catabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.


positive regulation of miRNA transcription

Any process that activates or increases the frequency, rate or extent of microRNA (miRNA) gene transcription.


negative regulation of chemokine (C-C motif) ligand 20 production

Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.


negative regulation of UDP-N-acetylglucosamine biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.


positive regulation of mitochondrial RNA catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.


positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.


regulation of tatiopterin metabolic process

Any process that modulates the frequency, rate or extent of tatiopterin metabolic process.


negative regulation of indoleacetic acid biosynthetic process via tryptophan

Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.


positive regulation of sphingolipid biosynthetic process

Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).


positive regulation of telomere maintenance via semi-conservative replication

Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


regulation of integrin biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.


regulation of interleukin-17 production

Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.


positive regulation of mRNA catabolic process

Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.


regulation of chitin biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.


positive regulation of interleukin-4 production

Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.


regulation of cardiolipin metabolic process

Any process that modulates the frequency, rate or extent of cardiolipin metabolic process.


positive regulation of lipophagy

Any process that activates or increases the frequency, rate or extent of lipophagy.


positive regulation of methanophenazine biosynthetic process

Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.


RNA destabilization

Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.


negative regulation of chemokine (C-X-C motif) ligand 9 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


regulation of mRNA catabolic process

Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.


positive regulation of mRNA alternative polyadenylation

Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation.


positive regulation of error-prone translesion synthesis

Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.


positive regulation of interleukin-10 production

Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.


positive regulation of sulfate assimilation

Any process that activates or increases the frequency, rate or extent of sulfate assimilation.


positive regulation of (R)-mevalonic acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.


positive regulation of snoRNA metabolic process

Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process.


negative regulation of autophagy of mitochondrion

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation by autophagy.


regulation of interleukin-35 production

Any process that modulates the frequency, rate, or extent of interleukin-35 production.


regulation of UDP-glucose catabolic process

Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.


positive regulation of capsule polysaccharide biosynthetic process

Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


regulation of indoleacetic acid biosynthetic process via tryptophan

Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.


positive regulation of mRNA processing

Any process that activates or increases the frequency, rate or extent of mRNA processing.


positive regulation of exoribonuclease activity

Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.


positive regulation of purine nucleobase metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.


regulation of pre-miRNA processing

Any process that modulates the frequency, rate or extent of pre-microRNA processing.


regulation of exoribonuclease activity

Any process that modulates the frequency, rate or extent of exoribonuclease activity.


regulation of nitric-oxide synthase biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.


negative regulation of serotonin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.


induction of phytoalexin biosynthetic process

The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection.


regulation of superoxide metabolic process

Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.


regulation of fumagillin biosynthetic process

Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process.


positive regulation of sarcinapterin metabolic process

Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process.


regulation of transcription from RNA polymerase II promoter in response to oxidative stress

Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.


regulation of purine nucleotide biosynthetic process

Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.


regulation of macrophage colony-stimulating factor production

Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.


post-fertilization epigenetic regulation of gene expression

A epigenetic process that happens during embryonic development that modulates gene expression potential at later stages of development of the organism, including the adult. Epigenetic regulation takes place via chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine DNA methylation.


positive regulation of transforming growth factor beta3 activation

Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation.


regulation of demethylkotanin biosynthetic process

Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.


regulation of interleukin-27 production

Any process that modulates the frequency, rate, or extent of interleukin-27 production.


negative regulation of heptadecane biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process.


positive regulation of sulfur metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.


positive regulation of transcription from RNA polymerase II promoter by glucose

Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.


positive regulation of ent-pimara-8(14),15-diene biosynthetic process

Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.


regulation of pyrimidine nucleobase metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.


positive regulation of antibacterial peptide production

Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.


negative regulation of post-transcriptional gene silencing

Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.


positive regulation of transforming growth factor beta2 production

Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.


regulation of MHC class I biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.


regulation of transforming growth factor beta activation

Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.


regulation of mitochondrial mRNA catabolic process

Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.


regulation of reactive oxygen species biosynthetic process

Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process.


positive regulation of type I interferon production

Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


regulatory ncRNA-mediated gene silencing

A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.


positive regulation of camalexin biosynthetic process

Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.


negative regulation of superoxide anion generation

Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.


negative regulation of ent-pimara-8(14),15-diene biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.


positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity

Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.


negative regulation of sulfur metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.


negative regulation of B cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.


negative regulation of removal of superoxide radicals

Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals.


regulation of transcription involved in meiotic cell cycle

Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle.


negative regulation of phosphatidylserine metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process.


regulation of double-strand break repair via homologous recombination

Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.


negative regulation of tridecane biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process.


regulation of photosynthesis, light reaction

Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis.


regulation of ribonuclease activity

Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


regulation of transcription-coupled nucleotide-excision repair

Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.


positive regulation of polynucleotide 3'-phosphatase activity

Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity.


regulation of sulfate assimilation

Any process that modulates the frequency, rate or extent of sulfate assimilation.


negative regulation of phospholipid metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.


negative regulation of cellular biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.


regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.


regulation of glycolytic fermentation to ethanol

Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol.


regulation of hydrogen peroxide biosynthetic process

Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.


regulation of nonadec-1-ene biosynthetic process

Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process.


regulatory ncRNA-mediated heterochromatin formation

A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginnning of trancription.


regulation of DNA recombination at telomere

Any process that modulates the frequency, rate or extent of DNA recombination within the telomere.


positive regulation of phosphate metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.


regulation of chemokine (C-C motif) ligand 6 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


positive regulation of guanylate cyclase activity

Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.


regulation of piRNA transcription

Any process that modulates the frequency, rate or extent of the synthesis of a piRNA.


positive regulation of reticulophagy

Any process that increases the frequency, rate or extent of reticulophagy.


negative regulation of sarcinapterin metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process.


regulation of ascospore wall beta-glucan biosynthetic process

Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


negative regulation of myeloid dendritic cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.


regulation of fructose 1,6-bisphosphate 1-phosphatase activity

Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.


negative regulation of photosynthesis, light reaction

Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.


regulation of hydrogen peroxide catabolic process

Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process.


regulation of cellular organohalogen metabolic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.


positive regulation of interleukin-20 production

Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.


negative regulation of interleukin-17A production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production.


positive regulation of RNA splicing

Any process that activates or increases the frequency, rate or extent of RNA splicing.


positive regulation of nitric-oxide synthase biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.


positive regulation of kinase activity

Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


photosystem II stabilization

The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.


positive regulation of DNA metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.


positive regulation of DNA recombination at telomere

Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.


negative regulation of IP-10 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.


positive regulation of tumor necrosis factor production

Any process that activates or increases the frequency, rate or extent of tumor necrosis factor production.


regulation of deoxyribonuclease activity

Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.


regulation of interleukin-22 production

Any process that modulates the frequency, rate, or extent of interleukin-22 production.


positive regulation of gene expression via CpG island demethylation

An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.


positive regulation of transforming growth factor beta1 production

Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.


regulation of lncRNA transcription

Any process that modulates the frequency, rate or extent of the synthesis of a lncRNA.


positive regulation of interleukin-11 production

Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.


negative regulation of hydrogen peroxide metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.


regulation of violaceol II biosynthetic process

Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process.


regulation of membrane lipid metabolic process

Any process that modulates the frequency, rate or extent of membrane lipid metabolic process.


positive regulation of removal of superoxide radicals

Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals.


negative regulation of xenophagy

Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy.


regulation of tRNA methylation

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tRNA methylation.


regulation of diacylglycerol kinase activity

Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity.


negative regulation of amylopectin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process.


negative regulation of phosphorylation

Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.


regulation of cysteine metabolic process

Any process that modulates the frequency, rate or extent of cysteine metabolic process.


negative regulation of interleukin-15 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.


negative regulation of selenocysteine metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine metabolic process.


activation of recombination (HML)

The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.


regulation of regulatory ncRNA processing

Any process that modulates the frequency, rate or extent of regulatory non-coding RNA processing.


RNAi-mediated antiviral immunity against DNA virus

An RNAi-mediated post-transcriptional gene silencing pathway induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL3 is the primary Dicer to detect DNA viruses.


positive regulation of transcription initiation by RNA polymerase II

Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.


negative regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


negative regulation of thyroid hormone generation

Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.


positive regulation of mRNA splicing, via spliceosome

Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.


positive regulation of hormone biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.


positive regulation of cytokine production

Any process that activates or increases the frequency, rate or extent of production of a cytokine.


regulation of replicative senescence

Any process that modulates the frequency, rate or extent of replicative senescence.


negative regulation of chemokine (C-C motif) ligand 1 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


cytoplasmic sequestering of NF-kappaB

The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.


negative regulation of phosphate metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.


negative regulation of interleukin-21 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.


positive regulation of glycolytic process

Any process that activates or increases the frequency, rate or extent of glycolysis.


regulation of methane biosynthetic process from methylamine

Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine.


regulation of syringal lignin catabolic process

Any process that modulates the frequency, rate or extent of syringal lignin catabolic process.


regulation of macrophage cytokine production

Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


positive regulation of phosphatidic acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.


regulation of polyamine biosynthetic process

Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.


positive regulation of transforming growth factor beta2 activation

Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation.


regulation of interleukin-17A production

Any process that modulates the frequency, rate or extent of interleukin-17A production.


dosage compensation by hyperactivation of X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.


positive regulation of interleukin-18 production

Any process that activates or increases the frequency, rate, or extent of interleukin-18 production.


positive regulation of tRNA catabolic process

Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.


negative regulation of isoprenoid metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.


negative regulation of cellular organohalogen metabolic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.


negative regulation of cytokine production involved in inflammatory response

Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.


negative regulation of aggrephagy

Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy.


positive regulation of toluene metabolic process

Any process that activates or increases the frequency, rate or extent of toluene metabolic process.


positive regulation of snRNA transcription by RNA polymerase II

Any process that activates or increases the frequency, rate or extent of snRNA transcription mediated by RNA polymerase II.


positive regulation of purine nucleotide biosynthetic process

Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.


negative regulation of macroautophagy

Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.


positive regulation of thiamine biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.


negative regulation melanotic encapsulation of foreign target

Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.


The organization of chromatin into heterochromatin at the pericentric region of a chromosome.


negative regulation of phospholipid biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


positive regulation of transcription from RNA polymerase II promoter in response to cold

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.


negative regulation of sinapate ester biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.


regulation of telomerase activity

Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.


negative regulation of glial cell-derived neurotrophic factor production

Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production.


regulation of plant-type cell wall cellulose biosynthetic process

Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.


regulation of replication fork arrest at rDNA repeats

Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.


regulation of toluene metabolic process

Any process that modulates the frequency, rate or extent of toluene metabolic process.


positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.


negative regulation of autophagosome maturation

Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation.


negative regulation of phosphorus utilization

Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization.


positive regulation of DNA-templated DNA replication

Any process that activates or increases the frequency, rate or extent of DNA-templated DNA replication.


positive regulation of cellular senescence

Any process that activates or increases the frequency, rate or extent of cellular senescence.


regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.


positive regulation of catecholamine metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.


regulation of syringal lignin biosynthetic process

Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.


positive regulation of phospholipid biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.


positive regulation of platelet-derived growth factor production

Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


photosynthetic state transition

A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.


negative regulation of alkaline phosphatase activity

Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.


positive regulation of isoprenoid metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.


negative regulation of mitochondrial ATP synthesis coupled proton transport

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.


positive regulation of telomere maintenance via telomere lengthening

Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.


spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.


positive regulation of phosphorus metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.


positive regulation of xenophagy

Any process that activates or increases the frequency, rate or extent of xenophagy.


regulation of inositol trisphosphate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.


positive regulation of interleukin-15 production

Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.


regulation of phosphatidate phosphatase activity

Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity.


regulation of dendritic cell cytokine production

Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.


positive regulation of estrogen biosynthetic process

Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process.


facultative heterochromatin formation

The compaction of chromatin into a conformation that is refactory to transcription but that be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression).


regulation of promoter clearance from RNA polymerase II promoter

A process that modulates the frequency, rate or extent of the transition from the initiation to the elongation phases of transcription by RNA polymerase II.


negative regulation of methane biosynthetic process from methanethiol

Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol.


mRNA localization resulting in post-transcriptional regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell.


positive regulation of melanization defense response

Any process that increases the rate or extent of the melanization defense response during injury or invasion.


regulation of glucokinase activity

Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.


regulation of deadenylation-independent decapping of nuclear-transcribed mRNA

Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.


regulation of steroid hormone biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.


positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.


positive regulation of reactive oxygen species biosynthetic process

Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.


regulation of gene silencing by regulatory ncRNA

Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.


negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.


positive regulation of interleukin-34 production

Any process that activates or increases the frequency, rate or extent of interleukin-34 production.


regulation of termination of RNA polymerase II transcription

Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription.


regulation of mitochondrial DNA metabolic process

Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.


positive regulation of juvenile hormone metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.


positive regulation of nuclease activity

Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.


negative regulation of bioluminescence

Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence.


regulation of mRNA stability involved in response to stress

Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.


positive regulation of heme biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


negative regulation of phosphatidylcholine catabolic process

Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.


regulation of chlorophyll biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.


regulation of amphiregulin production

Any process that modulates the frequency, rate, or extent of production of amphiregulin.


positive regulation of interleukin-25 production

Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.


regulation of brassinosteroid biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.


regulation of miRNA transcription

Any process that modulates the frequency, rate or extent of microRNA (miRNA) gene transcription.


positive regulation of rRNA processing

Any process that activates or increases the frequency, rate or extent of rRNA processing.


negative regulation of MHC class I biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.


regulation of interleukin-12 production

Any process that modulates the frequency, rate, or extent of interleukin-12 production.


positive regulation of hydrogen sulfide biosynthetic process

Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.


regulation of coenzyme A biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A.


regulation of heptadecane biosynthetic process

Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process.


regulation of telomere maintenance

Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.


positive regulation of octadecene metabolic process

Any process that activates or increases the frequency, rate or extent of octadecene metabolic process.


negative regulation of methane biosynthetic process from dimethyl sulfide

Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.


positive regulation of interleukin-35 production

Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.


negative regulation of interleukin-8 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.


regulation of vitamin D biosynthetic process

Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).


positive regulation of macrophage cytokine production

Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


retrotransposon silencing by RNA-directed DNA methylation

A retrotransposon silencing mechanism mediated by RNA-directed DNA methylation. RNA-directed DNA methylation is a gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.


regulation of antimicrobial peptide production

Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.


positive regulation of gene expression

Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


negative regulation of receptor catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process.


positive regulation of transcription from RNA polymerase II promoter in response to heat stress

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.


positive regulation of interferon-beta production

Any process that activates or increases the frequency, rate, or extent of interferon-beta production.


positive regulation of pyrimidine-containing compound salvage

Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage.


regulation of mRNA processing

Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.


positive regulation of interleukin-12 production

Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.


regulation of alpha-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.


negative regulation of iron-sulfur-molybdenum cofactor assembly

Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.


negative regulation of production of molecular mediator of immune response

Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.


positive regulation of inositol-polyphosphate 5-phosphatase activity

Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.


negative regulation of heme biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.


negative regulation of oxytocin production

Any process that stops, prevents, or reduces the rate of production of oxytocin.


positive regulation of interleukin-22 production

Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.


regulation of mismatch repair

Any process that modulates the frequency, rate or extent of mismatch repair.


regulation of glycogen biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.


positive regulation of interleukin-3 production

Any process that activates or increases the frequency, rate, or extent of interleukin-3 production.


positive regulation of glycolytic fermentation to ethanol

Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol.


positive regulation of pyrimidine nucleotide biosynthetic process

Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.


regulation of 18-methylnonadec-1-ene biosynthetic process

Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.


positive regulation of DNA ligase activity

Any process that activates or increases the frequency, rate or extent of DNA ligase activity.


negative regulation of hexadecanal biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process.


The formation of heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering piRNA.


positive regulation of chemokine (C-X-C motif) ligand 1 production

Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.


positive regulation of amylopectin catabolic process

Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process.


regulation of pyocyanine biosynthetic process

Any process that modulates the frequency, rate or extent of a pyocyanine biosynthetic process.


positive regulation of T-helper 1 cell cytokine production

Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production.


regulation of snoRNA processing

Any process that modulates the frequency, rate or extent of snoRNA processing.


positive regulation of nucleoside metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.


miRNA-mediated gene silencing

A post-transcriptional gene silencing pathway in which regulatory microRNAs (miRNAs) elicit silencing of specific target genes. miRNAs are endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate protein production by either of two posttranscriptional mechanisms: endonucleolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. miRNAs are present in all the animals and in plants, whereas siRNAs are present in lower animals and in plants.


photosystem stoichiometry adjustment

Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis.


regulation of interferon-alpha production

Any process that modulates the frequency, rate, or extent of interferon-alpha production.


negative regulation of macrophage inflammatory protein-1 gamma production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.


positive regulation of hh target transcription factor activity

Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.


negative regulation of ergosterol biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.


regulation of pentadecane metabolic process

Any process that modulates the frequency, rate or extent of pentadecane metabolic process.


positive regulation of post-transcriptional gene silencing

Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.


positive regulation of phytol biosynthetic process

Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process.


regulation of mRNA alternative polyadenylation

Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.


positive regulation of mitotic recombination-dependent replication fork processing

Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart.


negative regulation of interleukin-7 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.


negative regulation of tumor necrosis factor production

Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.


regulation of hydrogen sulfide biosynthetic process

Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process.


regulation of mitochondrial electron transport, NADH to ubiquinone

Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.


regulation of exodeoxyribonuclease activity

Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity.


regulation of cellulose biosynthetic process

Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.


regulation of transforming growth factor beta1 production

Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.


regulation of mRNA cis splicing, via spliceosome

Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.


RNAi-mediated antiviral immune response

A post-transcriptional gene silencing pathway mediated by the action of regulatory RNAs that protects against foreign organism invasion by restricting viral replication and dissemination.


regulation of myeloid dendritic cell cytokine production

Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.


negative regulation of sphingolipid biosynthetic process

Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).


positive regulation of DNA recombination

Any process that activates or increases the frequency, rate or extent of DNA recombination.


regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


positive regulation of DNA amplification

Any process that activates or increases the frequency, rate or extent of DNA amplification.


positive regulation of bioluminescence

Any process that activates or increases the frequency, rate or extent of bioluminescence.


regulation of hexadecanal biosynthetic process

Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process.


regulation of electron transfer activity

Any process that modulates the frequency, rate or extent of electron transfer activity.


negative regulation of cellulose biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.


epigenetic programing of female pronucleus

The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1.


positive regulation of auxin biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.


positive regulation of chemokine (C-C motif) ligand 6 production

Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


negative regulation of gluconeogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.


regulation of DNA double-strand break processing

Any process that modulates the frequency, rate or extent of DNA double-strand break processing.


regulation of interleukin-9 production

Any process that modulates the frequency, rate, or extent of interleukin-9 production.


regulation of nitrate assimilation

Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.


regulation of generation of precursor metabolites and energy

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.


regulation of RNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.


positive regulation of reverse transcription

Any process that activates or increases the frequency, rate or extent of reverse transcription.


constitutive heterochromatin formation

The compaction of chromatin into a conformation that is refactory to transcription.


positive regulation of auxin metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.


positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation

Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose.


regulation of 3'-UTR-mediated mRNA stabilization

Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.


regulation of mRNA metabolic process

Any process that modulates the frequency, rate or extent of mRNA metabolic process.


regulation of juvenile hormone biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.


negative regulation of brassinosteroid biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.


negative regulation of type III interferon production

Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


regulation of phenylpropanoid metabolic process

Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.


regulation of chemokine (C-C motif) ligand 20 production

Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.


regulation of chemokine (C-C motif) ligand 1 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


cytoplasmic sequestering of transcription factor

The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.


regulation of phosphatase activity

Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.


regulation of capsule polysaccharide biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


negative regulation of tatiopterin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process.


negative regulation of macrophage inflammatory protein 1 alpha production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


negative regulation of spermidine biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process.


negative regulation of (R)-mevalonic acid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of (R)-mevalonic acid biosynthetic process.


regulation of thyroid hormone generation

Any process that modulates the frequency, rate or extent of thyroid hormone generation.


negative regulation of melanin biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.


negative regulation of cordyol C biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process.


regulation of rRNA processing

Any process that modulates the frequency, rate or extent of rRNA processing.


inactivation of X chromosome by heterochromatin formation

Compensating for the two-fold variation in X-chromosome: autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.


negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine

Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.


negative regulation of calcidiol 1-monooxygenase activity

Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.


regulation of quinolinate biosynthetic process

Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process.


regulation of DNA catabolic process

Any process that modulates the frequency, rate or extent of DNA catabolic process.


regulation of nucleoside metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.


regulation of estrogen biosynthetic process

Any process that modulates the frequency, rate or extent of estrogen biosynthetic process.


negative regulation of mitophagy

Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy.


regulation of endothelin production

Any process that modulates the frequency, rate or extent of endothelin production.


regulation of transcription by RNA polymerase III

Any process that modulates the frequency, rate or extent of transcription mediated by RNA ploymerase III.


regulation of DNA methylation

Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.


positive regulation of transcription by galactose

Any process involving galactose that activates or increases the rate of transcription.


negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.


negative regulation of cellular senescence

Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.


positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway

Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.


lumenal side of lysosomal membrane

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The side (leaflet) of the lysosomal membrane that faces the lumen.


metanephric distal convoluted tubule development

The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.


distal convoluted tubule development

The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.


4-ketotorulene 3-hydroxylase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O.


notum development

The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure.


diacetyl reductase ((S)-acetoin forming) activity

Catalysis of the reaction: (S)-acetoin + NAD+ = diacetyl + H+ + NADH.


(+)-abscisic acid 8'-hydroxylase activity

Catalysis of the reaction: (+)-abscisate + H+ + NADPH + O2 = (+)-8'-hydroxyabscisate + H2O + NADP+.


cysteine-type deNEDDylase activity

An thiol-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.


corolla development

The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.


Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.


interleukin-3 production

The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


micronucleus organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.


modulation by symbiont of host B-cell mediated immune response

Any process in which a symbiont modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


suppression by symbiont of host B-cell mediated immune response

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


first cell cycle pseudocleavage

A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms.


pseudocleavage

Partial constriction of the cytoplasm of a cell to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.


pseudocleavage involved in syncytial blastoderm formation

Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.


first spliceosomal transesterification activity

Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.


L(+)-tartrate dehydratase activity

Catalysis of the reaction: L-tartrate = H2O + oxaloacetate.


positive regulation of protein localization to adherens junction

Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


C-19 gibberellin 2-beta-dioxygenase activity

Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons.


gibberellin 2-beta-dioxygenase activity

Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.


C-20 gibberellin 2-beta-dioxygenase activity

Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons.


glutamate catabolic process via L-citramalate

The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate.


Lewy body core

The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.


detection of jasmonic acid stimulus

The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.


negative regulation of RNA import into nucleus

Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.


regulation of store-operated calcium channel activity

Any process that modulates the frequency, rate or extent of store-operated calcium channel activity.


regulation of calcium ion transmembrane transporter activity

Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.


negative regulation of store-operated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.


regulation of high voltage-gated calcium channel activity

Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity.


activation of store-operated calcium channel activity

A process that initiates the activity of an inactive store-operated calcium channel.


regulation of ATPase-coupled calcium transmembrane transporter activity

Any process that modulates the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.


negative regulation of calcium ion transmembrane transporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.


positive regulation of ATPase-coupled calcium transmembrane transporter activity

Any process that activates or increases the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.


regulation of ryanodine-sensitive calcium-release channel activity

Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


negative regulation of ATPase-coupled calcium transmembrane transporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of an ATPase-coupled calcium transmembrane transporter activity.


negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


positive regulation of calcium ion transmembrane transporter activity

Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity.


negative regulation of high voltage-gated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity.


positive regulation of store-operated calcium channel activity

Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity.


regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


positive regulation of ryanodine-sensitive calcium-release channel activity

Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


regulation of light-activated voltage-gated calcium channel activity

Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity.


positive regulation of voltage-gated calcium channel activity

Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.


negative regulation of ryanodine-sensitive calcium-release channel activity

Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.


positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


negative regulation of voltage-gated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.


regulation of voltage-gated calcium channel activity

Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.


The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-).


peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine

The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine.


peptidyl-arginine hydroxylation

The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.


peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine

The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine.


oxylipin biosynthetic process

The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.


positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus

Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.


negative regulation of mediator complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly.


negative regulation of cardiac muscle cell myoblast differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.


Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP.


positive regulation of branching morphogenesis of a nerve

Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.


regulation of branching morphogenesis of a nerve

Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.


negative regulation of branching morphogenesis of a nerve

Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.


negative regulation of vascular wound healing

Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


negative regulation of angiogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.


negative regulation of cell adhesion involved in sprouting angiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.


negative regulation of sprouting angiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.


negative regulation of vessel branching

Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.


feminization of hermaphroditic germ-line

The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.


germ-line sex determination

The determination of sex and sexual phenotype in an organism's germ line.


male germ-line sex determination

The determination of sex and sexual phenotype in a male organism's germ line.


masculinization of hermaphroditic germ-line

The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.


hermaphrodite germ-line sex determination

The determination of sex and sexual phenotype in the germ line of a hermaphrodite.


female germ-line sex determination

The determination of sex and sexual phenotype in a female organism's germ line.


Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate.


TNFSF11 binding

Binding to tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.


chlorophyllase activity

Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.


glomerular filtration

The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.


negative regulation of toll-like receptor 1 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


isobutanol metabolic process

The chemical reactions and pathways involving isobutanol.


valine catabolic process to isobutanol

The chemical reactions and pathways resulting in the breakdown of valine to isobutanol.


isobutanol biosynthetic process

The chemical reactions and pathways resulting in the formation of isobutanol.


glycine catabolic process to isobutanol

The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol.


microtubule nucleation by microtubule organizing center

The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.


microtubule nucleation

The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).


microtubule nucleation by spindle pole body

The 'de novo' formation of a microtubule, mediated by the spindle pole body.


The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.


The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin.


microtubule nucleation by interphase microtubule organizing center

The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.


mitotic spindle-templated microtubule nucleation

The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle.


double-stranded DNA helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix.


adaptive immune memory response involving T cells and B cells

An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.


adaptive immune memory response

An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.


inositol 2-dehydrogenase activity

Catalysis of the reaction: myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + H+ + NADH.


alcohol dehydrogenase (NAD+) activity

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.


Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde.


butanol dehydrogenase activity

Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+.


alcohol dehydrogenase activity, zinc-dependent

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.


alcohol dehydrogenase activity, iron-dependent

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron.


xanthoxin dehydrogenase activity

Catalysis of the reaction: NAD+ + xanthoxin = (+)-abscisic aldehyde + H+ + NADH.


alcohol dehydrogenase activity, metal ion-independent

Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion.


regulation of timing of meristematic phase transition

Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point.


regulation of timing of transition from vegetative to reproductive phase

The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.


histone H3K27 trimethyltransferase activity

Catalysis of the reaction: L-lysyl27-[histone H3] + 3 S-adenosyl-L-methionine = 3 H+ + N6,N6,N6-trimethyl-L-lysyl27-[histone H3] + 3 S-adenosyl-L-homocysteine. This reaction is the successive addition of three methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me3.


histone H3K27 methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group to the lysine residue at position 27 of the histone H3 protein.


histone H3K27 monomethyltransferase activity

Catalysis of the reaction: L-lysyl27-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl27-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me.


histone H3K27 dimethyltransferase activity

Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.


non-professional antigen presenting cell antigen processing and presentation

The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils.


glucosamine kinase activity

Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate.


negative regulation of muscle cell chemotaxis toward tendon cell

Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells.


regulation of muscle cell chemotaxis toward tendon cell

Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell.


positive regulation of skeletal muscle satellite cell proliferation

Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation.


positive regulation of skeletal muscle cell proliferation

Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.


positive regulation of growth factor dependent skeletal muscle satellite cell proliferation

Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.


limbic system development

The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.


zinc D-Ala-D-Ala carboxypeptidase activity

Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine.


positive regulation of cellodextrin catabolic process

Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process.


positive regulation of cellodextrin metabolic process

Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process.


positive regulation of xylan catabolic process

Any process that activates or increases the frequency, rate or extent of xylan catabolic process.


positive regulation of arabinoxylan-containing compound catabolic process

Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process.


positive regulation of mannan catabolic process

Any process that activates or increases the frequency, rate or extent of mannan catabolic process.


positive regulation of glucuronoxylan catabolic process

Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process.


positive regulation of glucuronoarabinoxylan catabolic process

Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process.


positive regulation of glucomannan catabolic process

Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process.


kanamycin biosynthetic process

The chemical reactions and pathways resulting in the formation of kanamycin.


aminoglycoside antibiotic biosynthetic process

The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.


gentamycin biosynthetic process

The chemical reactions and pathways resulting in the formation of gentamycin.


neomycin biosynthetic process

The chemical reactions and pathways resulting in the formation of neomycin.


paromomycin biosynthetic process

The chemical reactions and pathways resulting in the formation of paromomycin.


coronary vein morphogenesis

The process in which the anatomical structures of veins of the heart are generated and organized.


negative regulation of lactation

Any process that stops, prevents or reduces the frequency, rate or extent of lactation.


microtubule minus-end binding

Binding to the minus end of a microtubule.


decanoate-[HmqF protein] ligase activity

Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein.


butyryl-CoA biosynthetic process

The chemical reactions and pathway resulting in the formation of butyryl-CoA.


butyryl-CoA biosynthetic process from acetyl-CoA

The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA.


protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


Catalysis of the reaction: D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4.


metanephric mesenchymal cell migration

The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.