B0LBX4_9VIRU Putative nuclear shuttle protein (trembl)


cytoplasm

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.


host cell cytoplasm

The cytoplasm of a host cell.


host cell nucleus

A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.


viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.


B0LBX6_9VIRU Putative movement protein (trembl)


membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it.


B0LBX8_9VIRU Putative replicase protein (trembl)


RNA binding

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Binding to an RNA molecule or a portion thereof.


RNA helicase activity

Unwinding of an RNA helix, driven by ATP hydrolysis.


catalytic activity

Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.


nucleotidyltransferase activity

Catalysis of the transfer of a nucleotidyl group to a reactant.


endodeoxyribonuclease activity, producing 5'-phosphomonoesters

Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.


DNA replication

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.


metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.


K4JUL8_ABHV DNA-directed DNA polymerase (trembl)


nucleotide binding

Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.


nucleic acid binding

Binding to a nucleic acid.


DNA binding

Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).


DNA-directed DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.


viral DNA genome replication

The replication of a viral DNA genome.


K4JUM2_ABHV Putative tRNA ligase (trembl)


ligase activity

Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient.


K4JUM7_ABHV Uncharacterized protein (trembl)


DNA ligase activity

Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.


DNA ligase (ATP) activity

Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).


ATP binding

Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.


DNA repair

The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.


DNA recombination

Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.


DNA damage response

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.


DNA biosynthetic process

The biosynthetic process resulting in the formation of DNA.


K4JV15_ABHV Uncharacterized protein (trembl)


K4JV20_ABHV Uncharacterized protein (trembl)


K4JV33_ABHV ribonucleoside-diphosphate reductase (trembl)


ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor

Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.


oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.


metal ion binding

Binding to a metal ion.


The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


K4JV47_ABHV Putative DEAD-box ATP-dependent RNA helicase (trembl)


helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.


hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.


K4JV51_ABHV Uncharacterized protein (trembl)


K4JV75_ABHV Uncharacterized protein (trembl)


K4JVA2_ABHV Eukaryotic translation initiation factor 3 30 kDa subunit (trembl)


K4JX26_ABHV Uncharacterized protein (trembl)


K4JX31_ABHV Uncharacterized protein (trembl)


K4JX33_ABHV Putative DNA packaging terminase (trembl)


chromosome organization

A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.


K4JX37_ABHV Uncharacterized protein (trembl)


K4JX93_ABHV PHTF1/2 N-terminal domain-containing protein (trembl)


K4JYD8_ABHV Putative eukaryotic translation initiation factor (trembl)


translation initiation factor activity

Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.


translation

The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.


translational initiation

The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.


K4JYG0_ABHV Putative DNA replication origin-binding helicase (trembl)


DNA replication origin binding

Binding to a DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.


K4JYG8_ABHV Uncharacterized protein (trembl)


K4JYH2_ABHV Uncharacterized protein (trembl)


K4JYI3_ABHV Uncharacterized protein (trembl)


K4JYK0_ABHV Putative methyltransferase (trembl)


methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.


methylation

The process in which a methyl group is covalently attached to a molecule.


K4JYM5_ABHV Putative guanylate kinase (trembl)


kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.


phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.


K4K8F3_ABHV Uncharacterized protein (trembl)


K4K8G2_ABHV Ribonucleoside-diphosphate reductase (trembl)


K4K8H0_ABHV Uncharacterized protein (trembl)


K4K8L0_ABHV Uncharacterized protein (trembl)


K4K8L9_ABHV Putative chloride channel (trembl)


K4K8M7_ABHV Uncharacterized protein (trembl)


A0A223FUM6_9VIRU Capsid protein (trembl)


structural molecule activity

The action of a molecule that contributes to the structural integrity of a complex.


RNA-dependent RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.


mRNA methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.


transferase activity

Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.


RNA-templated transcription

The synthesis of an RNA transcript from an RNA template.


DNA-templated transcription

The synthesis of an RNA transcript from a DNA template.


RNA processing

Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.


viral RNA genome replication

The replication of a viral RNA genome.


mRNA methylation

The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.


A0A191KW42_9VIRU M polyprotein (Fragment) (trembl)


mitigation of host antiviral defense response

A process by which a virus avoids or tolerates the effects of its host organism's defenses. Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.


host cell Golgi apparatus

A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.


host cell Golgi membrane

The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus.


virion component

Any constituent part of a virion, a complete fully infectious extracellular virus particle.


viral nucleocapsid

The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.


helical viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.


ribonucleoprotein complex

A macromolecular complex that contains both RNA and protein molecules.


A0A191KW45_9VIRU RNA-directed RNA polymerase L (trembl)


viral genome replication

Any process involved directly in viral genome replication, including viral nucleotide metabolism.


viral entry into host cell

The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.


viral penetration into host nucleus

The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid.


T=1 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.


REN_ABMVW Replication enhancer protein (sprot)


viral process

A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.


TRAP_ABMVW Transcriptional activator protein (sprot)


NSP_ABMVW Nuclear shuttle protein (sprot)


single-stranded DNA binding

Binding to single-stranded DNA.


transport of virus in host, cell to cell

The transport of a virus between adjacent cells in a multicellular organism.


DNA transport

The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


host cell plasma membrane

The plasma membrane surrounding a host cell.


host cell membrane

Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.


host cell

A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.


host intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.


host cell endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).


host cell endoplasmic reticulum membrane

The lipid bilayer surrounding the host cell endoplasmic reticulum.


REP_ABMVW Replication-associated protein (sprot)


nuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids.


endonuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.


YL666_MIMIV Uncharacterized protein L666 (sprot)


ATP hydrolysis activity

Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.


COLL7_MIMIV Collagen-like protein 7 (sprot)


YL673_MIMIV Putative serine/threonine-protein kinase L673 (sprot)


protein kinase activity

Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.


protein serine/threonine kinase activity

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.


protein serine kinase activity

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.


YL670_MIMIV Putative serine/threonine-protein kinase L670 (sprot)


YR679_MIMIV Putative serine/threonine-protein kinase R679 (sprot)


YL678_MIMIV Putative SET domain-containing protein L678 (sprot)


UVE1H_MIMIV Putative UV-damage endonuclease (sprot)


nucleotide-excision repair

A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).


response to UV

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.


YL682_MIMIV Uncharacterized protein L682 (sprot)


YR694_MIMIV Uncharacterized protein R694 (sprot)


MGMT_MIMIV Probable methylated-DNA--protein-cysteine methyltransferase (sprot)


Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.


YR692_MIMIV Uncharacterized protein R692 (sprot)


YR691_MIMIV Uncharacterized protein R691 (sprot)


YL688_MIMIV Uncharacterized protein L688 (sprot)


YL690_MIMIV Uncharacterized protein L690 (sprot)


UNAP_MIMIV Probable UDP-N-acetylglucosamine pyrophosphorylase (sprot)


Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.


The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.


biosynthetic process

The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.


YL701_MIMIV Uncharacterized protein L701 (sprot)


YR695_MIMIV Uncharacterized protein R695 (sprot)


YR707_MIMIV Uncharacterized protein R707 (sprot)


glycosyltransferase activity

Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).


YR706_MIMIV Uncharacterized protein R706 (sprot)


YR705_MIMIV Uncharacterized protein R705 (sprot)


YL720_MIMIV Endonuclease 8-like L720 (sprot)


damaged DNA binding

Binding to damaged DNA.


DNA-(apurinic or apyrimidinic site) endonuclease activity

Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER).


zinc ion binding

Binding to a zinc ion (Zn).


hydrolase activity, hydrolyzing N-glycosyl compounds

Catalysis of the hydrolysis of any N-glycosyl bond.


base-excision repair

In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.


YL716_MIMIV Putative glutamine amidotransferase-like protein L716 (sprot)


glutamine metabolic process

The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.


YL725_MIMIV Uncharacterized protein L725 (sprot)


YL724_MIMIV Uncharacterized protein L724 (sprot)


YR722_MIMIV Uncharacterized protein R722 (sprot)


metallopeptidase activity

Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.


YR721_MIMIV Uncharacterized protein R721 (sprot)


CFXQ_MIMIV Putative cfxQ-like protein R730 (sprot)


YR727_MIMIV Uncharacterized protein R727 (sprot)


YL733_MIMIV Uncharacterized ABC transporter ATP-binding protein/permease L733 (sprot)


YL742_MIMIV Putative BTB/POZ domain-containing protein L742 (sprot)


protein homooligomerization

The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.


Y749_MIMIV Putative homeobox protein R749 (sprot)


YR756_MIMIV Uncharacterized protein R756 (sprot)


iron-sulfur cluster binding

Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms.


4 iron, 4 sulfur cluster binding

Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.


YR866_MIMIV Uncharacterized protein R866 (sprot)


YR260_MIMIV DnaJ-like protein R260 (sprot)


Hsp70 protein binding

Binding to a Hsp70 protein, heat shock proteins around 70kDa in size.


heat shock protein binding

Binding to a heat shock protein, a protein synthesized or activated in response to heat shock.


unfolded protein binding

Binding to an unfolded protein.


protein folding

The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.


YR259_MIMIV Uncharacterized protein R259 (sprot)


magnesium ion binding

Binding to a magnesium (Mg) ion.


tRNA guanylyltransferase activity

Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.


tRNA modification

The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.


tRNA 5'-end processing

The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.


thymidine kinase activity

Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.


deoxyribonucleoside monophosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.


YR853_MIMIV Uncharacterized protein R853 (sprot)


YL851_MIMIV Uncharacterized protein L851 (sprot)


aminoacyl-tRNA ligase activity

Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.


cysteine-tRNA ligase activity

Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).


tRNA aminoacylation for protein translation

The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis.


YL872_MIMIV Uncharacterized protein L872 (sprot)


YR646_MIMIV Uncharacterized protein R646 (sprot)


RFCS3_MIMIV Putative replication factor C small subunit L499 (sprot)


YL585_MIMIV Uncharacterized protein L585 (sprot)


YR596_MIMIV Probable FAD-linked sulfhydryl oxidase R596 (sprot)


flavin-dependent sulfhydryl oxidase activity

Catalysis of the reaction: [protein]-dithiol + O2 = [protein]-disulfide + H2O2 using FAD as a cofactor, leading to formation of disulfide bridges in proteins.


thiol oxidase activity

Catalysis of the reaction: 2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + 2 H2O2.


YR595_MIMIV Uncharacterized protein R595 (sprot)


P4H_MIMIV Putative prolyl 4-hydroxylase (sprot)


Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.


iron ion binding

Binding to an iron (Fe) ion.


oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.


L-ascorbic acid binding

Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.


dioxygenase activity

Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.


YR592_MIMIV Putative helicase R592 (sprot)


ATP-dependent chromatin remodeler activity

An activity, driven by ATP hydrolysis, that modulates the contacts between histones and DNA, resulting in a change in chromosome architecture within the nucleosomal array, leading to chromatin remodeling.


chromatin remodeling

A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.


YL591_MIMIV Uncharacterized protein L591 (sprot)


YL606_MIMIV Uncharacterized protein L606 (sprot)


PPIL_MIMIV Structural PPIase-like protein L605 (sprot)


peptidyl-prolyl cis-trans isomerase activity

Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).


YR614_MIMIV Putative band 7 family protein R614 (sprot)


plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.


YL612_MIMIV Uncharacterized protein L612 (sprot)


YR001_MIMIV Putative replication origin-binding protein (sprot)


YR008_MIMIV Uncharacterized putative helicase R8 (sprot)


YL020_MIMIV Uncharacterized protein L20 (sprot)


YL016_MIMIV Uncharacterized protein L16 (sprot)


Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.


YL033_MIMIV Putative KilA-N domain-containing protein L33 (sprot)


YL032_MIMIV Putative KilA-N domain-containing protein L32 (sprot)


YR040_MIMIV Uncharacterized protein R40 (sprot)


YL048_MIMIV Uncharacterized protein L48 (sprot)


YL065_MIMIV Uncharacterized protein L65 (sprot)


COLL1_MIMIV Collagen-like protein 1 (sprot)


YL068_MIMIV Uncharacterized protein L68 (sprot)


YR080_MIMIV Putative resolvase R80 (sprot)


DNA strand exchange activity

Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.


regulation of DNA-templated transcription

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.


DNA integration

The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.


YL079_MIMIV TnpB-like protein L79 (sprot)


transposition

Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. For elements that are transcribed as the first step of transposition, the process starts with the transcription of the transposable element, its translation and maturation, and ending with integration into DNA. For elements that are cut out, the process starts with the excision of the donor DNA and integrated into another site.


YR104_MIMIV Putative transposase R104 (sprot)


YL103_MIMIV Putative resolvase L103 (sprot)


YL115_MIMIV Putative helicase L115 (sprot)


YR119_MIMIV Uncharacterized protein R119 (sprot)


tyrosine-tRNA ligase activity

Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H+.


identical protein binding

Binding to an identical protein or proteins.


protein homodimerization activity

Binding to an identical protein to form a homodimer.


tyrosine binding

Binding to 2-amino-3-(4-hydroxyphenyl)propanoic acid.


tyrosyl-tRNA aminoacylation

The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. The tyrosyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a tyrosine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


YR132_MIMIV Uncharacterized protein R132 (sprot)


YL128_MIMIV Putative GMC-type oxidoreductase L128 (sprot)


oxidoreductase activity, acting on CH-OH group of donors

Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.


flavin adenine dinucleotide binding

Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.


YR135_MIMIV Putative GMC-type oxidoreductase R135 (sprot)


YL153_MIMIV Uncharacterized protein L153 (sprot)


YR151_MIMIV Uncharacterized acetyltransferase R151 (sprot)


acetyltransferase activity

Catalysis of the transfer of an acetyl group to an acceptor molecule.


acyltransferase activity

Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).


YR160_MIMIV Uncharacterized protein R160 (sprot)


YL759_MIMIV Uncharacterized protein L759 (sprot)


YR758_MIMIV Uncharacterized protein R758 (sprot)


5'-nucleotidase activity

Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.


deoxyribonucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.


YR771_MIMIV Putative resolvase R771 (sprot)


YL770_MIMIV TnpB-like protein L770 (sprot)


YL778_MIMIV Uncharacterized protein L778 (sprot)


YR776_MIMIV Uncharacterized protein R776 (sprot)


COLL5_MIMIV Collagen-like protein 5 (sprot)


COLL4_MIMIV Collagen-like protein 4 (sprot)


ATP-dependent peptidase activity

Catalysis of the hydrolysis of peptide bonds, driven by ATP hydrolysis.


serine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).


peptidase activity

Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.


serine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).


proteolysis

The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.


protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.


TF2B_MIMIV Putative transcription initiation factor IIB-like protein (sprot)


TBP-class protein binding

Binding to a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).


DNA-templated transcription initiation

The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.


transcription preinitiation complex assembly

The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), required for transcription.


UNG_MIMIV Probable uracil-DNA glycosylase (sprot)


uracil DNA N-glycosylase activity

Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.


YL248_MIMIV Uncharacterized protein L248 (sprot)


YL247_MIMIV Uncharacterized HNH endonuclease L247 (sprot)


hydrolase activity, acting on ester bonds

Catalysis of the hydrolysis of any ester bond.


YL245_MIMIV Uncharacterized HNH endonuclease L245 (sprot)


HSP7L_MIMIV Heat shock protein 70 homolog (sprot)


ATP-dependent protein folding chaperone

Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.


YR253_MIMIV Uncharacterized protein R253 (sprot)


YR252_MIMIV Uncharacterized protein R252 (sprot)


DNA protection

Any process in which DNA is protected from damage by, for example, oxidative stress.


YL268_MIMIV Putative serine/threonine-protein kinase L268 (sprot)


YL264_MIMIV Uncharacterized WD repeat-containing protein L264 (sprot)


YL274_MIMIV Uncharacterized protein L274 (sprot)


YL280_MIMIV Uncharacterized acetyltransferase L280 (sprot)


YR277_MIMIV Uncharacterized protein R277 (sprot)


MCAR_MIMIV Mitochondrial carrier-like protein L276 (sprot)


host cell mitochondrion

A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.


host cell mitochondrial inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae.


YL275_MIMIV Putative BTB/POZ domain-containing protein L275 (sprot)


YR287_MIMIV Uncharacterized protein R287 (sprot)


YL282_MIMIV Uncharacterized protein L282 (sprot)


UBPL2_MIMIV Putative ubiquitin carboxyl-terminal hydrolase L293 (sprot)


cysteine-type deubiquitinase activity

An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.


cysteine-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


YR290_MIMIV Putative ATP-dependent RNA helicase R290 (sprot)


3'-5' DNA helicase activity

Unwinding a DNA helix in the direction 5' to 3', driven by ATP hydrolysis.


DNA duplex unwinding

The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.


YL288_MIMIV Putative B-type lectin protein L288 (sprot)


carbohydrate binding

Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.


COLL3_MIMIV Collagen-like protein 3 (sprot)


RPO5_MIMIV DNA-directed RNA polymerase subunit 5 (sprot)


DNA-directed 5'-3' RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.


5'-3' RNA polymerase activity

Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.


DNA-directed RNA polymerase complex

A protein complex that possesses DNA-directed RNA polymerase activity.


YL233_MIMIV Putative zinc protease L233 (sprot)


YL294_MIMIV Uncharacterized protein L294 (sprot)


RNH_MIMIV Probable ribonuclease H (sprot)


RNA-DNA hybrid ribonuclease activity

Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.


END4_MIMIV Putative endonuclease 4 (sprot)


deoxyribonuclease IV (phage-T4-induced) activity

Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.


cellular anatomical entity

A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex.


YR305_MIMIV Uncharacterized protein R305 (sprot)


DNA ligase (NAD+) activity

Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).


YR302_MIMIV Uncharacterized protein R302 (sprot)


YR301_MIMIV Putative serine/threonine-protein kinase R301 (sprot)


YR311_MIMIV Putative RING finger protein R311 (sprot)


YL310_MIMIV Uncharacterized protein L310 (sprot)


YL309_MIMIV Uncharacterized protein L309 (sprot)


YR307_MIMIV PP2C-like domain-containing protein R307 (sprot)


protein serine/threonine phosphatase activity

Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.


GNA1_MIMIV Probable glucosamine 6-phosphate N-acetyltransferase (sprot)


glucosamine 6-phosphate N-acetyltransferase activity

Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H+.


acyltransferase activity, transferring groups other than amino-acyl groups

Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).


FPG_MIMIV Probable formamidopyrimidine-DNA glycosylase (sprot)


oxidized purine nucleobase lesion DNA N-glycosylase activity

Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.


hydrolase activity, acting on glycosyl bonds

Catalysis of the hydrolysis of any glycosyl bond.


lyase activity

Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.


DNA N-glycosylase activity

Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.


class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Catalysis of the cleavage of an AP site 3' of the baseless site by a beta-lyase mechanism, leaving an unsaturated aldehyde, termed a 3'-(4-hydroxy-5-phospho-2-pentenal) residue, and a 5'-phosphate.


YL193_MIMIV Uncharacterized glycosyltransferase L193 (sprot)


COLL2_MIMIV Collagen-like protein 2 (sprot)


GLRX_MIMIV Probable glutaredoxin (sprot)


YR197_MIMIV Uncharacterized protein R197 (sprot)


YL208_MIMIV Uncharacterized protein L208 (sprot)


YL207_MIMIV Putative helicase L207/L206 (sprot)


hydrolase activity, acting on acid anhydrides

Catalysis of the hydrolysis of any acid anhydride.


YL205_MIMIV Putative serine/threonine-protein kinase L205 (sprot)


RABL_MIMIV Probable Rab-related GTPase (sprot)


GTPase activity

Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.


GTP binding

Binding to GTP, guanosine triphosphate.


protein transport

The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


YR213_MIMIV Uncharacterized protein R213 (sprot)


YL211_MIMIV Uncharacterized protein L211 (sprot)


RPO6_MIMIV DNA-directed RNA polymerase subunit 6 (sprot)


YL813_MIMIV Uncharacterized protein L813 (sprot)


YR811_MIMIV Putative ariadne-like RING finger protein R811 (sprot)


YL798_MIMIV Uncharacterized protein L798 (sprot)


extracellular region

The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.


UBC4_MIMIV Probable bifunctional E2/E3 enzyme R795 (sprot)


ubiquitin-protein transferase activity

Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y = Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.


ubiquitin conjugating enzyme activity

Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y = Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.


protein ubiquitination

The process in which one or more ubiquitin groups are added to a protein.


YR390_MIMIV Uncharacterized protein R390 (sprot)


YL389_MIMIV Uncharacterized protein L389 (sprot)


YL396_MIMIV Putative ATP-dependent RNA helicase L396 (sprot)


RFCS1_MIMIV Putative replication factor C small subunit R395 (sprot)


HSP70_MIMIV Heat shock 70 kDa protein homolog (sprot)


COLL6_MIMIV Collagen-like protein 6 (sprot)


YL712_MIMIV Uncharacterized protein L712 (sprot)


YR710_MIMIV Uncharacterized protein R710 (sprot)


UBC2_MIMIV Probable ubiquitin-conjugating enzyme E2 L709 (sprot)


arginine-tRNA ligase activity

Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).


arginyl-tRNA aminoacylation

The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


YR655_MIMIV Putative glycosyltransferase R655 (sprot)


YR654_MIMIV Putative fucosyltransferase R654 (sprot)


fucosyltransferase activity

Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.


protein glycosylation

A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.


YR653_MIMIV Uncharacterized protein R653 (sprot)


DNMK_MIMIV Putative deoxynucleotide monophosphate kinase (sprot)


Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate.


YL511_MIMIV Uncharacterized protein L511 (sprot)


RFCS4_MIMIV Putative replication factor C small subunit L510 (sprot)


YL509_MIMIV Uncharacterized protein L509 (sprot)


YR519_MIMIV Putative zinc metalloproteinase R519 (sprot)


metalloendopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.


YR517_MIMIV Putative serine/threonine-protein kinase R517/R518 (sprot)


YL516_MIMIV Uncharacterized protein L516 (sprot)


YL515_MIMIV Uncharacterized protein L515 (sprot)


YR513_MIMIV Uncharacterized protein R513 (sprot)


YR526_MIMIV Putative alpha/beta hydrolase R526 (sprot)


RHBDL_MIMIV Putative rhomboid protein L523 (sprot)


UBC3_MIMIV Probable ubiquitin-conjugating enzyme E2 R521 (sprot)


YL520_MIMIV Putative BTB/POZ domain-containing protein L520 (sprot)


YL532_MIMIV Cytochrome P450-like protein L532 (sprot)


monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.


heme binding

Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.


YR528_MIMIV Putative 5'-3' exonuclease R528 (sprot)


exonuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.


YL540_MIMIV Putative ATP-dependent RNA helicase L540 (sprot)


YL538_MIMIV Putative ATP-dependent RNA helicase L538 (sprot)


YL536_MIMIV Uncharacterized protein L536 (sprot)


YL533_MIMIV Uncharacterized protein L533 (sprot)


YR545_MIMIV HMG box-containing protein R545 (sprot)


YL544_MIMIV Uncharacterized protein L544 (sprot)


ADPRM_MIMIV Putative ADP-ribosyl glycohydrolase L543 (sprot)


YR541_MIMIV Putative BTB/POZ domain-containing protein R541 (sprot)


YR217_MIMIV Uncharacterized protein R217 (sprot)


TOP1P_MIMIV DNA topoisomerase 1 type prokaryotic (sprot)


DNA topoisomerase activity

Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.


DNA topoisomerase type I (single strand cut, ATP-independent) activity

Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.


isomerase activity

Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.


DNA topological change

The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.


YR224_MIMIV Putative BTB/POZ domain-containing protein R224 (sprot)


YL222_MIMIV Putative SET domain-containing protein L222 (sprot)


YL232_MIMIV Putative serine/threonine-protein kinase L232 (sprot)


PLOD_MIMIV Procollagen lysyl hydroxylase and glycosyltransferase (sprot)


Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.


UBC1_MIMIV Probable ubiquitin-conjugating enzyme E2 L460 (sprot)


YR459_MIMIV Uncharacterized protein R459 (sprot)


YR458_MIMIV Putative ATP-dependent RNA helicase R458 (sprot)


PNKP_MIMIV Putative bifunctional polynucleotide phosphatase/kinase (sprot)


polynucleotide 3'-phosphatase activity

Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.


ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity

Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.


ATP-dependent polynucleotide 5'-hydroxyl-kinase activity

Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.


YR468_MIMIV Uncharacterized protein R468 (sprot)


SUI1_MIMIV Protein translation factor SUI1 homolog (sprot)


regulation of translation

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.


YR463_MIMIV Uncharacterized protein R463 (sprot)


YR470_MIMIV Putative DNA directed RNA polymerase subunit R470 (sprot)


protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.


YR476_MIMIV Putative AAA family ATPase R476 (sprot)


SNARE complex disassembly

The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.


ASNS_MIMIV Probable asparagine synthetase [glutamine-hydrolyzing] (sprot)


asparagine synthase (glutamine-hydrolyzing) activity

Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.


asparagine biosynthetic process

The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.


nitrogen compound metabolic process

The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.


amino acid biosynthetic process

The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.


L-asparagine biosynthetic process

The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.


YR474_MIMIV Uncharacterized protein R474 (sprot)


YR472_MIMIV Uncharacterized protein R472 (sprot)


DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity

Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined, driven by ATP hydrolysis. The enzyme changes the linking number in multiples of 2.


DNA metabolic process

Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.


RFCS2_MIMIV Putative replication factor C small subunit L478 (sprot)


YL477_MIMIV Uncharacterized peptidase C1-like protein L477 (sprot)


YL484_MIMIV Putative ankyrin repeat protein L484 (sprot)


YL485_MIMIV Uncharacterized protein L485 (sprot)


YR489_MIMIV Uncharacterized protein R489 (sprot)


YL488_MIMIV Uncharacterized protein L488 (sprot)


YL487_MIMIV Uncharacterized protein L487 (sprot)


YR486_MIMIV Putative PAN domain-containing protein R486 (sprot)


YL492_MIMIV Uncharacterized protein L492 (sprot)


YL498_MIMIV Probable zinc-type alcohol dehydrogenase-like protein L498 (sprot)


oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.


DRTS_MIMIV Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)


dihydrofolate reductase activity

Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.


thymidylate synthase activity

Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.


transferase activity, transferring one-carbon groups

Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).


dTMP biosynthetic process

The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).


one-carbon metabolic process

The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.


nucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).


tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.


IF4EH_MIMIV Eukaryotic translation initiation factor 4E homolog (sprot)


YR495_MIMIV Uncharacterized protein R495 (sprot)


YR818_MIMIV Putative serine/threonine-protein kinase/receptor R818 (sprot)


cyclic nucleotide biosynthetic process

The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.


intracellular signal transduction

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.


YL817_MIMIV Uncharacterized protein L817 (sprot)


53DR_MIMIV Putative 5'(3')-deoxyribonucleotidase R824 (sprot)


nucleotide metabolic process

The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).


YL823_MIMIV Uncharacterized protein L823 (sprot)


DNA polymerase processivity factor activity

An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.


regulation of DNA replication

Any process that modulates the frequency, rate or extent of DNA replication.


YR833_MIMIV Putative truncated GMC-type inactive oxidoreductase R833 (sprot)


YR832_MIMIV Putative truncated GMC-type inactive oxidoreductase R832 (sprot)


YL829_MIMIV Uncharacterized protein L829 (sprot)


YR809_MIMIV Uncharacterized protein R809 (sprot)


CP51_MIMIV Probable lanosterol 14-alpha demethylase (sprot)


sterol 14-demethylase activity

Catalysis of the reaction: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = a delta14 steroid + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].


lipid metabolic process

The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.


steroid biosynthetic process

The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.


steroid metabolic process

The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.


sterol biosynthetic process

The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.


DHCR7_MIMIV Probable 7-dehydrocholesterol reductase (sprot)


oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.


7-dehydrocholesterol reductase activity

Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+.


NADP binding

Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.


cholesterol biosynthetic process

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.


cholesterol metabolic process

The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.


YR836_MIMIV Uncharacterized protein R836 (sprot)


YR401_MIMIV Uncharacterized protein R401 (sprot)


YR400_MIMIV Putative serine/threonine-protein kinase R400 (sprot)


YL399_MIMIV Uncharacterized protein L399 (sprot)


YR398_MIMIV Uncharacterized protein R398 (sprot)


YR407_MIMIV Putative RNA methyltransferase R407 (sprot)


RNA methyltransferase activity

Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.


RNA methylation

Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.


YR406_MIMIV Uncharacterized protein R406 (sprot)


DNA dealkylation involved in DNA repair

The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT).


oxidative single-stranded DNA demethylation

Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.


YR405_MIMIV Putative RNA methyltransferase R405 (sprot)


YL404_MIMIV Putative alpha/beta hydrolase L404 (sprot)


YR403_MIMIV Uncharacterized protein R403 (sprot)


YR402_MIMIV Uncharacterized protein R402 (sprot)


YL412_MIMIV Uncharacterized protein L412 (sprot)


RFCL_MIMIV Putative replication factor C large subunit (sprot)


DNA clamp loader activity

Facilitating the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex, driven by ATP hydrolysis.


DNA replication factor C complex

A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.


YL410_MIMIV Putative core protein L410 (sprot)


NDK_MIMIV Nucleoside diphosphate kinase (sprot)


nucleoside diphosphate kinase activity

Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.


GTP biosynthetic process

The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.


UTP biosynthetic process

The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate.


CTP biosynthetic process

The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.


YL417_MIMIV Uncharacterized protein L417 (sprot)


YL416_MIMIV Uncharacterized protein L416 (sprot)


YR419_MIMIV Uncharacterized short-chain type dehydrogenase/reductase R419 (sprot)


YR431_MIMIV Putative 3'-5' exonuclease R431 (sprot)


3'-5' exonuclease activity

Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.


nucleobase-containing compound metabolic process

Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.


YR430_MIMIV Putative transcription factor R430 (sprot)


regulation of viral transcription

Any process that modulates the frequency, rate or extent of the transcription of the viral genome.


YR429_MIMIV Putative transcription factor R429 (sprot)


YL434_MIMIV Uncharacterized protein L434 (sprot)


YL432_MIMIV Uncharacterized protein L432 (sprot)


TR443_MIMIV Thioredoxin domain-containing protein R443 (sprot)


YL442_MIMIV Uncharacterized protein L442 (sprot)


CAPS3_MIMIV Probable capsid protein 3 (sprot)


YL438_MIMIV Putative TLC domain-containing protein L438 (sprot)


YL448_MIMIV Uncharacterized protein L448 (sprot)


YL446_MIMIV Uncharacterized protein L446 (sprot)


lipid catabolic process

The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.


ADPRL_MIMIV Putative ADP-ribosyl glycohydrolase L444 (sprot)


YR457_MIMIV Uncharacterized protein R457 (sprot)


YR455_MIMIV Uncharacterized protein R455 (sprot)


YL454_MIMIV Uncharacterized protein L454 (sprot)


TBPL_MIMIV TATA-box-binding protein-like (sprot)


YL452_MIMIV Uncharacterized protein L452 (sprot)


YL451_MIMIV Uncharacterized protein L451 (sprot)


YR854_MIMIV TnpB-like protein R854 (sprot)


YL320_MIMIV Uncharacterized protein L320 (sprot)


7-methylguanosine RNA capping

The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript.


macromolecule modification

The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.


primary metabolic process

The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.


UBPL1_MIMIV Probable ubiquitin carboxyl-terminal hydrolase R319 (sprot)


YR327_MIMIV Uncharacterized protein R327 (sprot)


YR326_MIMIV Uncharacterized protein R326 (sprot)


YL323_MIMIV Uncharacterized protein L323 (sprot)


YR331_MIMIV Putative zinc finger MYND domain-containing protein R331 (sprot)


YL330_MIMIV Uncharacterized protein L330 (sprot)


PAP1_MIMIV Putative poly(A) polymerase catalytic subunit (sprot)


poly(A) RNA polymerase activity

Catalysis of the reaction: ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. The primer may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.


mRNA processing

Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.


TFS2_MIMIV Transcription factor S-II-related protein (sprot)


YR335_MIMIV Uncharacterized protein R335 (sprot)


YR347_MIMIV Uncharacterized protein R347 (sprot)


YR345_MIMIV Uncharacterized protein R345 (sprot)


RNC_MIMIV Probable ribonuclease 3 (sprot)


ribonuclease III activity

Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.


rRNA processing

Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.


YR342_MIMIV Uncharacterized protein R342 (sprot)


YL352_MIMIV Uncharacterized protein L352 (sprot)


YR350_MIMIV Putative ATP-dependent RNA helicase R350 (sprot)


YR349_MIMIV Uncharacterized protein R349 (sprot)


MUTSL_MIMIV Putative DNA mismatch repair protein mutS homolog L359 (sprot)


mismatched DNA binding

Binding to a double-stranded DNA region containing one or more mismatches.


ATP-dependent DNA damage sensor activity

A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.


mismatch repair

A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.


YR355_MIMIV Putative thiol protease R355 (sprot)


cysteine-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


viral protein processing

Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.


YR372_MIMIV Uncharacterized protein R372 (sprot)


YR368_MIMIV Probable FAD-linked sulfhydryl oxidase R368 (sprot)


YL377_MIMIV Putative ATP-dependent RNA helicase L377 (sprot)


YL376_MIMIV Putative DNA-directed RNA polymerase subunit L376 (sprot)


DIPP_MIMIV Putative mRNA-decapping protein (sprot)


Catalysis of the reaction: diphospho-1D-myo-inositol polyphosphate + H2O = 1D-myo-inositol polyphosphate + phosphate.


YL374_MIMIV Uncharacterized protein L374 (sprot)


YL373_MIMIV Uncharacterized glycosyltransferase L373 (sprot)


YL388_MIMIV Uncharacterized protein L388 (sprot)


YR387_MIMIV Uncharacterized protein R387 (sprot)


YL386_MIMIV Putative endonuclease L386 (sprot)


YR383_MIMIV Uncharacterized protein R383 (sprot)


MCE_MIMIV Probable mRNA-capping enzyme (sprot)


Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.


mRNA guanylyltransferase activity

Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.


polynucleotide 5'-phosphatase activity

Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.


mRNA 5'-phosphatase activity

A 5'-end triphospho-[mRNA] + H2O = a 5'-end diphospho-[mRNA] + H+ + phosphate.


7-methylguanosine mRNA capping

Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.


RNA 5'-cap (guanine-N7)-methylation

The process whereby a guanine in 5-cap is methylated at the N7 position of guanine.


YL891_MIMIV Uncharacterized protein L891 (sprot)


YL887_MIMIV Putative JmjC domain-containing protein L887 (sprot)


YL894_MIMIV Putative truncated GMC-type inactive oxidoreductase L894 (sprot)


YL893_MIMIV Putative truncated GMC-type inactive oxidoreductase L893 (sprot)


YL899_MIMIV Uncharacterized protein L899 (sprot)


YR900_MIMIV Uncharacterized protein R900 (sprot)


YL908_MIMIV Uncharacterized protein L908 (sprot)


CHLE_MIMIV Probable cholinesterase (sprot)


cholinesterase activity

Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.


carboxylic ester hydrolase activity

Catalysis of the hydrolysis of a carboxylic ester bond.


YL905_MIMIV Uncharacterized protein L905 (sprot)


demethylation

The process of removing one or more methyl groups from a molecule.


YR648_MIMIV Uncharacterized protein R648 (sprot)


YL647_MIMIV Uncharacterized protein L647 (sprot)


TGDS_MIMIV Putative dTDP-D-glucose 4,6-dehydratase (sprot)


dTDP-glucose 4,6-dehydratase activity

Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.


nucleotide-sugar metabolic process

The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.


YR139_MIMIV Uncharacterized glycosyltransferase R139 (sprot)


YR660_MIMIV Uncharacterized protein R660 (sprot)


YR659_MIMIV Putative EGF-like domain-containing protein R659 (sprot)


YR658_MIMIV Uncharacterized protein R658 (sprot)


YR656_MIMIV Uncharacterized protein R656 (sprot)


YR366_MIMIV Putative ATP-dependent RNA helicase R366 (sprot)


YL364_MIMIV Putative ATP-dependent RNA helicase L364 (sprot)


YR363_MIMIV Uncharacterized glycosyltransferase R363 (sprot)


TR362_MIMIV Thioredoxin domain-containing protein R362 (sprot)


YL550_MIMIV Uncharacterized protein L550 (sprot)


YR557_MIMIV Uncharacterized protein R557 (sprot)


YR555_MIMIV Uncharacterized protein R555 (sprot)


double-strand break repair

The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.


YR553_MIMIV Uncharacterized protein R553 (sprot)


YL560_MIMIV Uncharacterized HNH endonuclease L560 (sprot)


YR559_MIMIV Uncharacterized HTH-type transcriptional regulator R559 (sprot)


GLNA_MIMIV Putative glutamine synthetase (sprot)


glutamate-ammonia ligase activity

Catalysis of the reaction: L-glutamate + ATP + NH3 = L-glutamine + ADP + 2 H+ + phosphate.


glutamine biosynthetic process

The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.


YL572_MIMIV Putative AAA family ATPase L572 (sprot)


YR571_MIMIV Uncharacterized protein R571 (sprot)


YR569_MIMIV Uncharacterized exonuclease R569 (sprot)


YR568_MIMIV Putative ATP-dependent DNA helicase R568 (sprot)


DNA helicase activity

Unwinding of a DNA helix, driven by ATP hydrolysis.


YL567_MIMIV Uncharacterized protein L567 (sprot)


YR584_MIMIV Uncharacterized N-acetyltransferase R584 (sprot)


YR802_MIMIV Uncharacterized protein R802 (sprot)


nucleoside metabolic process

The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).


YL801_MIMIV Uncharacterized protein L801 (sprot)


YR799_MIMIV Uncharacterized protein R799 (sprot)


NMT_MIMIV Putative glycylpeptide N-tetradecanoyltransferase (sprot)


Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.


YL620_MIMIV Uncharacterized protein L620 (sprot)


YR618_MIMIV Uncharacterized protein R618 (sprot)


YL615_MIMIV Putative phosphatidylinositol kinase L615 (sprot)


phosphatidylinositol phosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate.


phosphatidylinositol-mediated signaling

The series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.


YR624_MIMIV Putative GTP-binding protein R624 (sprot)


PTPH_MIMIV Putative tyrosine-protein phosphatase R622 (sprot)


phosphoprotein phosphatase activity

Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cellular proteins and thereby provide an important mechanism for regulating cellular activity.


protein tyrosine phosphatase activity

Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.


protein tyrosine/serine/threonine phosphatase activity

Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.


phosphatase activity

Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.


dephosphorylation

The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.


YR632_MIMIV Uncharacterized protein R632 (sprot)


fatty acid amide hydrolase activity

Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.


fatty acid metabolic process

The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.


lysosome

A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.


YL631_MIMIV Uncharacterized protein L631 (sprot)


TM189_MIMIV Probable fatty acid desaturase MIMI_L630 (sprot)


CYB5L_MIMIV Cytochrome b5-like protein (sprot)


YL633_MIMIV Putative lectin L633 (sprot)


SYM_MIMIV Methionine--tRNA ligase (sprot)


methionine-tRNA ligase activity

Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).


methionyl-tRNA aminoacylation

The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. The methionyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a methionine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


PEBPH_MIMIV Phosphatidylethanolamine-binding protein homolog R644 (sprot)


lipid binding

Binding to a lipid.


YL573_MIMIV Uncharacterized protein L573 (sprot)


YR877_MIMIV Putative lipocalin R877 (sprot)


YR188_MIMIV Uncharacterized protein R188 (sprot)


YR186_MIMIV Putative transposase R186 (sprot)


YR843_MIMIV Uncharacterized hydrolase R843 (sprot)


YR161_MIMIV Uncharacterized protein R161 (sprot)


YR610_MIMIV Uncharacterized protein R610 (sprot)


YR826_MIMIV Putative serine/threonine-protein kinase/receptor R826 (sprot)


YR563_MIMIV Putative ATP-dependent RNA helicase R563 (sprot)


CAPS2_MIMIV Probable capsid protein 2 (sprot)


RPO1_MIMIV DNA-directed RNA polymerase subunit 1 (sprot)


GFAT_MIMIV Probable glutamine--fructose-6-phosphate aminotransferase [isomerizing] (sprot)


glutamine-fructose-6-phosphate transaminase (isomerizing) activity

Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.


transaminase activity

Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.


carbohydrate derivative binding

Binding to a carbohydrate derivative.


carbohydrate derivative metabolic process

The chemical reactions and pathways involving carbohydrate derivative.


carbohydrate derivative biosynthetic process

The chemical reactions and pathways resulting in the formation of carbohydrate derivative.


RPO2_MIMIV DNA-directed RNA polymerase subunit 2 (sprot)


ribonucleoside binding

Binding to a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.


YR700_MIMIV Uncharacterized serpin-like protein R700 (sprot)


serine-type endopeptidase inhibitor activity

Binds to and stops, prevents or reduces the activity of a serine-type endopeptidase.


peptidase inhibitor activity

Binds to and stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.


extracellular space

That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.


TOP1E_MIMIV DNA topoisomerase 1B (sprot)


PCNA_MIMIV Probable DNA polymerase sliding clamp (sprot)


YR436_MIMIV Putative serine/threonine-protein kinase R436 (sprot)


YR831_MIMIV Putative serine/threonine-protein kinase/receptor R831 (sprot)


DPOLX_MIMIV Probable DNA polymerase family X (sprot)


DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.


CAPS4_MIMIV Probable capsid protein 4 (sprot)


RIR1_MIMIV Ribonucleoside-diphosphate reductase large subunit (sprot)


RIR2_MIMIV Ribonucleoside-diphosphate reductase small chain (sprot)


L7RB25_9VIRU Fragment of DNA-directed RNA polymerase subunit 1 (trembl)


L7RB29_9VIRU Uncharacterized protein (trembl)


L7RB39_9VIRU Phospholipid methyltransferase (trembl)


L7RB45_9VIRU Collagen repeat protein with BclB C-terminal domain (trembl)


L7RB58_9VIRU Flavin containing amine oxidoreductase (trembl)


L7RB66_9VIRU BTB family protein (trembl)


L7RB71_9VIRU DUF378 domain-containing protein (trembl)


L7RB94_9VIRU Potassium channel protein (trembl)


L7RB98_9VIRU SERPIN, SERine Proteinase INhibitor (trembl)


L7RBA4_9VIRU E2 ubiquitin-conjugating enzyme (trembl)


L7RBA8_9VIRU BAX inhibitor (BI)-1/YccA-like protein family (trembl)


L7RBB0_9VIRU Uncharacterized protein (trembl)


L7RBB6_9VIRU Zinc-dependent metalloprotease domain containing protein (trembl)


L7RBE7_9VIRU Putative Zn-dependent peptidase (trembl)


L7RBF4_9VIRU Putative intron HNH endonuclease (trembl)


L7RBF8_9VIRU Transcription initiation factor TFIIB (trembl)


L7RBG0_9VIRU Putative transposase (trembl)


L7RBH7_9VIRU Uncharacterized protein (trembl)


L7RBI1_9VIRU Translation initiation factor 4E (trembl)


L7RBJ3_9VIRU Putative replication factor C small subunit (trembl)


L7RBJ9_9VIRU Polynucleotide phosphatase/kinase (trembl)


L7RBL4_9VIRU Holliday junction resolvase (trembl)


L7RBM4_9VIRU Putative membrane protein (trembl)


L7RBN0_9VIRU Poxvirus late transcription factor VLTF3-like protein (trembl)


L7RBP2_9VIRU Uncharacterized protein (trembl)


L7RBP5_9VIRU Uncharacterized protein (trembl)


L7RBP6_9VIRU Replication factor C large subunit (trembl)


L7RBP9_9VIRU 2OG-Fe(II) oxygenase (trembl)


L7RBQ3_9VIRU RING-type E3 ubiquitin transferase (trembl)


L7RBQ6_9VIRU Putative ATP-dependent RNA helicase (trembl)


L7RBR2_9VIRU Cytochrome P450 fused to 2OG-Fe(II) oxygenase domain (trembl)


L7RBR4_9VIRU Uncharacterized protein (trembl)


L7RBR5_9VIRU 2OG-Fe(II) oxygenase superfamily protein (trembl)


L7RBR6_9VIRU Methyltransferase domain-containing protein (trembl)


L7RBR7_9VIRU mRNA-capping enzyme (trembl)


L7RBS2_9VIRU DEAD-like helicase (trembl)


L7RBT7_9VIRU Glycosyltransferase GTB-type domain-containing protein (trembl)


L7RBU7_9VIRU KilA N-domain protein (trembl)


L7RBV0_9VIRU Uncharacterized protein (trembl)


L7RBV9_9VIRU Putative poly(A) polymerase catalytic subunit (trembl)


L7RBW1_9VIRU Serine/Threonine protein kinase (trembl)


L7RBW3_9VIRU Uncharacterized protein (trembl)


L7RBX5_9VIRU Homeodomain-containing protein (trembl)


L7RBX8_9VIRU Cyclin domain fused to cyclin-dependent serine/threonine protein kinase (trembl)


L7RBX9_9VIRU Myristylated IMV envelope protein (trembl)


viral envelope

The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.


L7RBY0_9VIRU Putative glycosyltransferase (trembl)


L7RBY1_9VIRU DNA-directed RNA polymerase (trembl)


L7RBY3_9VIRU Peptidase C19 subfamily protein (trembl)


L7RBY4_9VIRU p-loop NTPase family protein (trembl)


L7RBY6_9VIRU Glutamine amidotransferase (trembl)


L7RBY9_9VIRU DNA-(apurinic or apyrimidinic site) lyase (trembl)


L7RBZ0_9VIRU Formamidopyrimidine-DNA glycosylase (trembl)


L7RBZ2_9VIRU Uncharacterized protein (trembl)


L7RBZ3_9VIRU BTB/POZ domain protein (trembl)


L7RBZ4_9VIRU Cu/Zn superoxide dismutase (trembl)


copper ion binding

Binding to a copper (Cu) ion.


superoxide metabolic process

The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.


L7RBZ8_9VIRU Serine/Threonine protein phosphatase (trembl)


L7RBZ9_9VIRU Uncharacterized protein (trembl)


L7RC00_9VIRU Glycosyltransferase_GTB_type super family protein (trembl)


L7RC02_9VIRU Putative divergent protein kinase (trembl)


L7RC09_9VIRU D5 family helicase-primase (trembl)


L7RC13_9VIRU VIP2 super family[cl00173] (trembl)


L7RC14_9VIRU Prepilin type IV endopeptidase peptidase domain-containing protein (trembl)


L7RC20_9VIRU procollagen-lysine 5-dioxygenase (trembl)


L7RC22_9VIRU Apple domain-containing protein (trembl)


L7RC25_9VIRU Guanine nucleotide exchange factor (trembl)


guanyl-nucleotide exchange factor activity

Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.


small GTPase mediated signal transduction

The series of molecular signals in which a small monomeric GTPase relays a signal.


L7RC28_9VIRU Uncharacterized protein (trembl)


L7RC30_9VIRU Collagen repeat protein (trembl)


L7RC34_9VIRU Deoxynucleotide monophosphate kinase (trembl)


L7RC40_9VIRU E2 ubiquitin-conjugating enzyme (trembl)


L7RC41_9VIRU Protein kinase family protein (trembl)


L7RC47_9VIRU Etoposide-induced protein 2.4 (trembl)


L7RC49_9VIRU Group I intron endonuclease (trembl)


L7RC53_9VIRU SNF2 family helicase (trembl)


protein-disulfide reductase activity

Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.


L7RC60_9VIRU Helix-turn-helix XRE-family like protein (trembl)


L7RC62_9VIRU RNA polymerase subunit 5 (trembl)


L7RC63_9VIRU Replication origin-binding helicase (trembl)


L7RC64_9VIRU Uncharacterized protein (trembl)


L7RC65_9VIRU PAN domain-containing protein (trembl)


L7RC67_9VIRU Collagen repeat protein (trembl)


L7RC68_9VIRU DNA topoisomerase 2 (trembl)


L7RC69_9VIRU Patatin-like phospholipase (trembl)


L7RC71_9VIRU Putative intron HNH endonuclease (trembl)


L7RC73_9VIRU Asparagine synthase (trembl)


L7RC75_9VIRU Uncharacterized protein (trembl)


L7RC84_9VIRU Glucose-methanol-choline oxidoreductase (trembl)


L7RC86_9VIRU Mannose-6P isomerase (trembl)


L7RC88_9VIRU DEAD/SNF2-like helicase (trembl)


L7RC89_9VIRU Phosphoinositide 3-kinase (trembl)


L7RC92_9VIRU glutamine--fructose-6-phosphate transaminase (isomerizing) (trembl)


L7RC93_9VIRU DNA-directed RNA polymerase subunit (trembl)


L7RC95_9VIRU Zn-dependent alcohol dehydrogenase (trembl)


L7RC98_9VIRU Putative ADP-ribosylglycohydrolase (trembl)


L7RCA1_9VIRU Uncharacterized protein (trembl)


L7RCA7_9VIRU Uncharacterized protein (trembl)


L7RCB1_9VIRU Deoxyribodipyrimidine photolyase-related protein (trembl)


L7RCB9_9VIRU Glycosyltransferase family 10 (trembl)


L7RCC0_9VIRU Nucleoside diphosphate kinase (trembl)


L7RCC5_9VIRU C3H1-type domain-containing protein (trembl)


L7RCD0_9VIRU SGNH_hydrolase super family (trembl)


lipase activity

Catalysis of the hydrolysis of a lipid or phospholipid.


L7RCD4_9VIRU Cell division cycle 123 protein (trembl)


cell division

The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.


L7RCD9_9VIRU Calcineurin-like phosphoesterase domain-containing protein (trembl)


L7RCE4_9VIRU HSP70-like protein (trembl)


L7RCE7_9VIRU Uncharacterized protein (trembl)


L7RCF2_9VIRU Uncharacterized protein (trembl)


L7RCF3_9VIRU Cyclin-domain fused to serine-threonine kinase (trembl)


L7RCG0_9VIRU FNIP repeat-containing protein (trembl)


L7RCG3_9VIRU Zinc finger protein (Eukaryotic) (trembl)


L7RCG5_9VIRU Putative virion-associated membrane protein (trembl)


L7RCH4_9VIRU ATP-dependent RNA helicase (trembl)


L7RCI2_9VIRU Uncharacterized protein (trembl)


L7RCI4_9VIRU Chromosomal protein MC1 domain-containing protein (trembl)


L7RCI5_9VIRU DNA mismatch repair ATPase MutS (trembl)


DNA-binding transcription factor activity

A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.


protein splicing

The post-translational removal of peptide sequences from within a protein sequence.


L7RCI6_9VIRU Alpha/beta hydrolase family protein (trembl)


L7RCJ3_9VIRU Putative KilA-N domain-containing protein (trembl)


L7RCJ6_9VIRU HD phosphohydrolase domain-containing protein (trembl)


L7RCJ7_9VIRU Collagen triple helix repeat protein (trembl)


L7RCK1_9VIRU Putative UV-damage endonuclease (trembl)


L7RCK3_9VIRU Cullin family profile domain-containing protein (trembl)


ubiquitin protein ligase binding

Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.


ubiquitin-dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.


L7RCK7_9VIRU Purine phosphorylase family 1 protein (trembl)


L7RCL4_9VIRU Putative DNA-directed RNA polymerase subunit (trembl)


L7RCL7_9VIRU Permuted papain-like amidase YaeF/Yiix C92 family enzyme (trembl)


L7RCM8_9VIRU Glycosyltransferase GTB-type domain-containing protein (trembl)


L7RCN0_9VIRU Glycosyltransferase_GTA_type super family protein (trembl)


L7RCN4_9VIRU RING domain-containing protein (trembl)


L7RCN7_9VIRU RNA polymerase Rpb6 (trembl)


L7RCN9_9VIRU Ulp1 protease (Eukaryotic) (trembl)


L7RCP1_9VIRU Uncharacterized protein (trembl)


L7RCP3_9VIRU SNF2 family helicase (trembl)


L7RCP5_9VIRU DNA ligase (NAD(+)) (trembl)


L7RCP9_9VIRU Putative low complexity protein (trembl)


L7RCQ7_9VIRU Uracil-DNA glycosylase family 1 (trembl)


L7RCQ8_9VIRU DUF4190 domain-containing protein (trembl)


L7RCR0_9VIRU Protein tyrosine phosphatase (trembl)


L7RCR3_9VIRU Putative metallopeptidase WLM (trembl)


L7RCR5_9VIRU Uncharacterized protein (trembl)


L7RCR6_9VIRU Serine/Threonine protein kinase (trembl)


L7RCR7_9VIRU DNA-directed DNA polymerase (trembl)


L7RCR8_9VIRU DEAD/SNF2 helicase (trembl)


L7RCS0_9VIRU DEAD/SNF2-like helicase (trembl)


L7RCS4_9VIRU Putative 5' nucleotidase (trembl)


L7RCS5_9VIRU Ribonucleoside-diphosphate reductase small chain (trembl)


L7RCS6_9VIRU Cyanovirin-N domain protein (trembl)


L7RCS7_9VIRU Uncharacterized protein (trembl)


L7RCS8_9VIRU Replication origin-binding protein (trembl)


L7RCT0_9VIRU thymidylate synthase (trembl)


L7RCT3_9VIRU Cytochrome P450 family protein (trembl)


L7RCT4_9VIRU Proliferating cell nuclear antigen (trembl)


L7RCT9_9VIRU Uncharacterized protein (trembl)


phosphomannomutase activity

Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.


GDP-mannose biosynthetic process

The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.


L7RCU4_9VIRU PAN domain-containing protein (trembl)


L7RCU5_9VIRU Uncharacterized protein (trembl)


L7RCU7_9VIRU Nucleoside Triphosphate Pyrophosphohydrolase (trembl)


L7RCV0_9VIRU Uncharacterized protein (trembl)


L7RCV2_9VIRU DNA 3'-5' helicase (trembl)


L7RCV3_9VIRU DNA directed RNA polymerase subunit L (trembl)


L7RCV8_9VIRU Peptidase C19 subfamily protein (trembl)


L7RCV9_9VIRU DEAD-like helicase (trembl)


L7RCW4_9VIRU Uncharacterized protein (trembl)


L7RCW7_9VIRU DUF2784 domain-containing protein (trembl)


L7RCW8_9VIRU Stomatin family protein (trembl)


L7RCX0_9VIRU Uncharacterized protein (trembl)


L7RCX2_9VIRU asparagine--tRNA ligase (trembl)


asparagine-tRNA ligase activity

Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H+.


asparaginyl-tRNA aminoacylation

The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.


L7RCX4_9VIRU Uncharacterized protein (trembl)


L7RCX5_9VIRU Dual specificity S/Y phosphatase (trembl)


L7RCX6_9VIRU Serine/Threonine kinase (trembl)


L7RCY0_9VIRU Integral membrane protein (trembl)


L7RCY1_9VIRU Uncharacterized protein (trembl)


L7RCY4_9VIRU Putative DNA helicase (trembl)


L7RCY6_9VIRU Bulb-type mannose-specific lectin (trembl)


L7RCY7_9VIRU Uncharacterized protein (trembl)


L7RCZ1_9VIRU HrpA-like helicase (trembl)


L7RCZ5_9VIRU Transmembrane protein (trembl)


L7RD01_9VIRU Putative DNA repair protein (trembl)


L7RD02_9VIRU Replication factor C large subunit (trembl)


L7RD07_9VIRU RNA methyltransferase (trembl)


L7RD08_9VIRU Glutamine synthetase (trembl)


L7RD13_9VIRU ATP-dependent helicase HrpA (trembl)


L7RD16_9VIRU Band 7 domain-containing protein (trembl)


L7RD19_9VIRU HSP70-like protein (trembl)


L7RD20_9VIRU Prolyl 4-hydroxylase (trembl)


L7RD21_9VIRU Arginyl-tRNA synthetase (trembl)


L7RD22_9VIRU Sulfhydryl oxidase (trembl)


L7RD25_9VIRU Cyclophilin family protein (trembl)


L7RD26_9VIRU Divergent methyltransferase (trembl)


L7RD35_9VIRU N-acetylglucosaminyl phosphatidylinositol deacetylase (trembl)


L7RD37_9VIRU glycylpeptide N-tetradecanoyltransferase (trembl)


L7RD43_9VIRU Cytochrome b5-like protein (trembl)


L7RD44_9VIRU Glycosyltransferase GTB-type domain-containing protein (trembl)


L7RD48_9VIRU Ntn (N-terminal nucleophile) hydrolase (trembl)


L7RD52_9VIRU DNA-directed RNA polymerase subunit N (trembl)


L7RD59_9VIRU Putative resolvase (trembl)


chromosome

A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.


L7RD67_9VIRU Uncharacterized protein (trembl)


L7RD69_9VIRU Endotype 6-aminohexanoat-oligomer hydrolase (trembl)


L7RD72_9VIRU Transmembrane protein (trembl)


L7RD76_9VIRU MYND-type domain-containing protein (trembl)


L7RD83_9VIRU Transmembrane protein (trembl)


L7RD84_9VIRU Myristylated IMV envelope protein (trembl)


L7RD88_9VIRU Putative RNA methylase (trembl)


L7RD90_9VIRU Arginyl-tRNA synthetase (trembl)


L7RD91_9VIRU Integral membrane protein (trembl)


L7RD92_9VIRU Glucosamine 6-phosphate N-acetyltransferase (trembl)


L7RD96_9VIRU Putative membrane protein (trembl)


L7RDA7_9VIRU Uncharacterized protein (trembl)


L7RDA8_9VIRU Cyclin-domain fused to serine-threonine kinase (trembl)


L7RDB2_9VIRU Apurinic endonuclease IV (trembl)


L7RDC8_9VIRU Mitochondrial carrier protein (trembl)


L7RDE0_9VIRU Putative ankyrin repeat protein (trembl)


L7RDE5_9VIRU Putative replication factor C small subunit (trembl)


L7RDE8_9VIRU GMC oxidoreductase (trembl)


L7RDF5_9VIRU BTB family protein (trembl)


L7RDF8_9VIRU Putative triacylglycerol lipase (trembl)


L7RDG6_9VIRU Transmembrane protein (trembl)


L7RDH5_9VIRU Metal dependent phosphohydrolase (trembl)


L7RDH7_9VIRU BTB family protein (trembl)


L7RDI7_9VIRU D6/D11-like helicase (trembl)


L7RDJ3_9VIRU Uncharacterized protein (trembl)


L7RDJ4_9VIRU BTB domain-containing protein (trembl)


L7RDJ7_9VIRU N-acetyltransferase domain-containing protein (trembl)


L7RDK4_9VIRU Alpha/beta hydrolase family protein (trembl)


L7RDL7_9VIRU Transmembrane protein (trembl)


L7RDM1_9VIRU Uncharacterized protein (trembl)


L7RDM3_9VIRU Phosphoinositide 3-kinase (trembl)


L7RDN7_9VIRU Putative ubiquitin-conjugating enzyme E2 (trembl)


L7RDP2_9VIRU Restriction endonuclease (trembl)


L7RDR4_9VIRU Putative 5' nucleotidase (trembl)


L7RDT2_9VIRU arginine--tRNA ligase (trembl)


L7RDU1_9VIRU Cyclin-domain fused to serine-threonine kinase (trembl)


L7RDW2_9VIRU Uncharacterized protein (trembl)


L7RDW5_9VIRU Exodeoxyribonuclease VII large subuni (trembl)


exodeoxyribonuclease VII activity

Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.


DNA catabolic process

The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.


exodeoxyribonuclease VII complex

An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.


L7RDY4_9VIRU GMC oxidoreductase (trembl)


L7RE36_9VIRU U-box domain-containing protein (trembl)


L7RE44_9VIRU KilA N-domain protein (trembl)


L7RFI6_9VIRU DNA topoisomerase 2 (trembl)


L7RFL6_9VIRU VWFA domain-containing protein (trembl)


L7RFR4_9VIRU MdlB[COG1132], ABC-type multidrug transport system (trembl)


L7RFS8_9VIRU N-acetylglucosamine-1-phosphate uridyltransferase (trembl)


L7RFT0_9VIRU SMODS and SLOG-associating 2TM effector domain-containing protein (trembl)


L7RFT5_9VIRU Uncharacterized protein (trembl)


L7RFU2_9VIRU Eukaryotic peptide chain release translation termination factor 1 (trembl)


translation release factor activity

Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.


translational termination

The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).


L7RFU5_9VIRU Stage V sporulation protein K (trembl)


L7RFV2_9VIRU Protein kinase domain-containing protein (trembl)


L7RFW9_9VIRU Collagen repeat protein (trembl)


L7RFX1_9VIRU DNA-directed RNA polymerase (trembl)


intein-mediated protein splicing

The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.


L7RFX4_9VIRU ATP-dependent Lon protease, bacterial type (trembl)


L7RFX6_9VIRU Putative site-specific integrase-resolvase (trembl)


L7RFX8_9VIRU isoleucine--tRNA ligase (trembl)


aminoacyl-tRNA editing activity

The hydrolysis of an incorrectly aminoacylated tRNA.


isoleucine-tRNA ligase activity

Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H+.


isoleucyl-tRNA aminoacylation

The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


aminoacyl-tRNA metabolism involved in translational fidelity

Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.


L7RFY5_9VIRU Uncharacterized protein (trembl)


L7RFZ3_9VIRU Uncharacterized protein (trembl)


L7RG00_9VIRU Uncharacterized protein (trembl)


L7RG05_9VIRU Cathepsin B, cystein protease (trembl)


L7RG09_9VIRU Uncharacterized protein (trembl)


L7RG10_9VIRU Eukaryotic initiation factor eIF1/SUI (trembl)


L7RG12_9VIRU E2 ubiquitin-conjugating enzyme (trembl)


L7RG13_9VIRU Uncharacterized protein (trembl)


L7RG15_9VIRU Holliday junction resolvase (trembl)


L7RG17_9VIRU Patatin-like phospholipase (trembl)


L7RG22_9VIRU Putative HD phosphohydrolase (trembl)


L7RG25_9VIRU Putative dehydrogenase (trembl)


L7RG27_9VIRU Uncharacterized protein (trembl)


L7RG28_9VIRU Poxvirus P4B major core protein (trembl)


L7RG29_9VIRU SAM-dependent methyltransferase (trembl)


L7RG33_9VIRU Putative replication factor C small subunit (trembl)


L7RG37_9VIRU Putative endonuclease of the XPG family (trembl)


L7RG42_9VIRU Ricin B lectin domain-containing protein (trembl)


L7RG47_9VIRU Sulfhydryl oxidase (trembl)


L7RG64_9VIRU TFII-like transcription factor (trembl)


L7RG71_9VIRU Uncharacterized protein (trembl)


L7RG79_9VIRU DNA-directed DNA polymerase (trembl)


L7RG82_9VIRU DNA polymerase family X (trembl)


L7RG84_9VIRU Ribonucleoside-diphosphate reductase (trembl)


L7RG89_9VIRU Uncharacterized protein (trembl)


L7RG93_9VIRU Uncharacterized protein (trembl)


L7RGC1_9VIRU Uncharacterized protein (trembl)


L7RGC3_9VIRU Uncharacterized protein (trembl)


L7RGE7_9VIRU Numod4 NHN endonuclease (trembl)


L7RGE9_9VIRU Type I cysteine dioxygenase (trembl)


oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.