L7RC13_9VIRU VIP2 super family[cl00173] (trembl)


L7RC14_9VIRU Prepilin type IV endopeptidase peptidase domain-containing protein (trembl)


L7RC20_9VIRU procollagen-lysine 5-dioxygenase (trembl)


L7RC22_9VIRU Apple domain-containing protein (trembl)


L7RC25_9VIRU Guanine nucleotide exchange factor (trembl)


guanyl-nucleotide exchange factor activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Stimulates the exchange of GDP to GTP on a signaling GTPase, changing its conformation to its active form. Guanine nucleotide exchange factors (GEFs) act by stimulating the release of guanosine diphosphate (GDP) to allow binding of guanosine triphosphate (GTP), which is more abundant in the cell under normal cellular physiological conditions.


small GTPase mediated signal transduction

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals in which a small monomeric GTPase relays a signal.


L7RC28_9VIRU Uncharacterized protein (trembl)


L7RC30_9VIRU Collagen repeat protein (trembl)


L7RC34_9VIRU Deoxynucleotide monophosphate kinase (trembl)


L7RC40_9VIRU E2 ubiquitin-conjugating enzyme (trembl)


L7RC41_9VIRU Protein kinase family protein (trembl)


L7RC47_9VIRU Etoposide-induced protein 2.4 (trembl)


L7RC49_9VIRU Group I intron endonuclease (trembl)


L7RC53_9VIRU SNF2 family helicase (trembl)


protein-disulfide reductase activity

Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.


L7RC60_9VIRU Helix-turn-helix XRE-family like protein (trembl)


L7RC62_9VIRU RNA polymerase subunit 5 (trembl)


L7RC63_9VIRU Replication origin-binding helicase (trembl)


L7RC64_9VIRU Uncharacterized protein (trembl)


L7RC65_9VIRU PAN domain-containing protein (trembl)


L7RC67_9VIRU Collagen repeat protein (trembl)


L7RC68_9VIRU DNA topoisomerase 2 (trembl)


L7RC69_9VIRU Patatin-like phospholipase (trembl)


L7RC71_9VIRU Putative intron HNH endonuclease (trembl)


L7RC73_9VIRU Asparagine synthase (trembl)


L7RC75_9VIRU Uncharacterized protein (trembl)


L7RC84_9VIRU Glucose-methanol-choline oxidoreductase (trembl)


L7RC86_9VIRU Mannose-6P isomerase (trembl)


L7RC88_9VIRU DEAD/SNF2-like helicase (trembl)


L7RC89_9VIRU Phosphoinositide 3-kinase (trembl)


L7RC92_9VIRU glutamine--fructose-6-phosphate transaminase (isomerizing) (trembl)


L7RC93_9VIRU DNA-directed RNA polymerase subunit (trembl)


L7RC95_9VIRU Zn-dependent alcohol dehydrogenase (trembl)


L7RC98_9VIRU Putative ADP-ribosylglycohydrolase (trembl)


L7RCA1_9VIRU Uncharacterized protein (trembl)


L7RCA7_9VIRU Uncharacterized protein (trembl)


L7RCB1_9VIRU Deoxyribodipyrimidine photolyase-related protein (trembl)


L7RCB9_9VIRU Glycosyltransferase family 10 (trembl)


L7RCC0_9VIRU Nucleoside diphosphate kinase (trembl)


L7RCC5_9VIRU C3H1-type domain-containing protein (trembl)


L7RCD0_9VIRU SGNH_hydrolase super family (trembl)


lipase activity

Catalysis of the hydrolysis of a lipid or phospholipid.


L7RCD4_9VIRU Cell division cycle 123 protein (trembl)


cell division

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.


L7RCD9_9VIRU Calcineurin-like phosphoesterase domain-containing protein (trembl)


L7RCE4_9VIRU HSP70-like protein (trembl)


L7RCE7_9VIRU Uncharacterized protein (trembl)


L7RCF2_9VIRU Uncharacterized protein (trembl)


L7RCF3_9VIRU Cyclin-domain fused to serine-threonine kinase (trembl)


L7RCG0_9VIRU FNIP repeat-containing protein (trembl)


L7RCG3_9VIRU Zinc finger protein (Eukaryotic) (trembl)


L7RCG5_9VIRU Putative virion-associated membrane protein (trembl)


L7RCH4_9VIRU ATP-dependent RNA helicase (trembl)


L7RCI2_9VIRU Uncharacterized protein (trembl)


L7RCI4_9VIRU Chromosomal protein MC1 domain-containing protein (trembl)


L7RCI5_9VIRU DNA mismatch repair ATPase MutS (trembl)


DNA-binding transcription factor activity

A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.


protein splicing

The post-translational removal of peptide sequences from within a protein sequence.


L7RCI6_9VIRU Alpha/beta hydrolase family protein (trembl)


L7RCJ3_9VIRU Putative KilA-N domain-containing protein (trembl)


L7RCJ6_9VIRU HD phosphohydrolase domain-containing protein (trembl)


L7RCJ7_9VIRU Collagen triple helix repeat protein (trembl)


L7RCK1_9VIRU Putative UV-damage endonuclease (trembl)


L7RCK3_9VIRU Cullin family profile domain-containing protein (trembl)


L7RCK7_9VIRU Purine phosphorylase family 1 protein (trembl)


L7RCL4_9VIRU Putative DNA-directed RNA polymerase subunit (trembl)


L7RCL7_9VIRU Permuted papain-like amidase YaeF/Yiix C92 family enzyme (trembl)


L7RCM8_9VIRU Glycosyltransferase GTB-type domain-containing protein (trembl)


L7RCN0_9VIRU Glycosyltransferase_GTA_type super family protein (trembl)


L7RCN4_9VIRU RING domain-containing protein (trembl)


L7RCN7_9VIRU RNA polymerase Rpb6 (trembl)


L7RCN9_9VIRU Ulp1 protease (Eukaryotic) (trembl)


L7RCP1_9VIRU Uncharacterized protein (trembl)


L7RCP3_9VIRU SNF2 family helicase (trembl)


L7RCP5_9VIRU DNA ligase (NAD(+)) (trembl)


L7RCP9_9VIRU Putative low complexity protein (trembl)


L7RCQ7_9VIRU Uracil-DNA glycosylase family 1 (trembl)


L7RCQ8_9VIRU DUF4190 domain-containing protein (trembl)


L7RCR0_9VIRU Protein tyrosine phosphatase (trembl)


L7RCR3_9VIRU Putative metallopeptidase WLM (trembl)


L7RCR5_9VIRU Uncharacterized protein (trembl)


L7RCR6_9VIRU Serine/Threonine protein kinase (trembl)


L7RCR7_9VIRU DNA-directed DNA polymerase (trembl)


L7RCR8_9VIRU DEAD/SNF2 helicase (trembl)


L7RCS0_9VIRU DEAD/SNF2-like helicase (trembl)


L7RCS4_9VIRU Putative 5' nucleotidase (trembl)


L7RCS5_9VIRU Ribonucleoside-diphosphate reductase small chain (trembl)


L7RCS6_9VIRU Cyanovirin-N domain protein (trembl)


L7RCS7_9VIRU Uncharacterized protein (trembl)


L7RCS8_9VIRU Replication origin-binding protein (trembl)


L7RCT0_9VIRU thymidylate synthase (trembl)


L7RCT3_9VIRU Cytochrome P450 family protein (trembl)


L7RCT4_9VIRU Proliferating cell nuclear antigen (trembl)


L7RCT9_9VIRU Uncharacterized protein (trembl)


phosphomannomutase activity

Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.


GDP-mannose biosynthetic process

The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.


L7RCU4_9VIRU PAN domain-containing protein (trembl)


L7RCU5_9VIRU Uncharacterized protein (trembl)


L7RCU7_9VIRU Nucleoside Triphosphate Pyrophosphohydrolase (trembl)


L7RCV0_9VIRU Uncharacterized protein (trembl)


L7RCV2_9VIRU DNA 3'-5' helicase (trembl)


L7RCV3_9VIRU DNA directed RNA polymerase subunit L (trembl)


L7RCV8_9VIRU Peptidase C19 subfamily protein (trembl)


L7RCV9_9VIRU DEAD-like helicase (trembl)


L7RCW4_9VIRU Uncharacterized protein (trembl)


L7RCW7_9VIRU DUF2784 domain-containing protein (trembl)


L7RCW8_9VIRU Stomatin family protein (trembl)


L7RCX0_9VIRU Uncharacterized protein (trembl)


L7RCX2_9VIRU asparagine--tRNA ligase (trembl)


asparagine-tRNA ligase activity

Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H+.


asparaginyl-tRNA aminoacylation

The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. The asparaginyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of an asparagine-accetping tRNA.


L7RCX4_9VIRU Uncharacterized protein (trembl)


L7RCX5_9VIRU Dual specificity S/Y phosphatase (trembl)


L7RCX6_9VIRU Serine/Threonine kinase (trembl)


L7RCY0_9VIRU Integral membrane protein (trembl)


L7RCY1_9VIRU Uncharacterized protein (trembl)


L7RCY4_9VIRU Putative DNA helicase (trembl)


L7RCY6_9VIRU Bulb-type mannose-specific lectin (trembl)


L7RCY7_9VIRU Uncharacterized protein (trembl)


L7RCZ1_9VIRU HrpA-like helicase (trembl)


L7RCZ5_9VIRU Transmembrane protein (trembl)


L7RD01_9VIRU Putative DNA repair protein (trembl)


L7RD02_9VIRU Replication factor C large subunit (trembl)


L7RD07_9VIRU RNA methyltransferase (trembl)


L7RD08_9VIRU Glutamine synthetase (trembl)


L7RD13_9VIRU ATP-dependent helicase HrpA (trembl)


L7RD16_9VIRU Band 7 domain-containing protein (trembl)


L7RD19_9VIRU HSP70-like protein (trembl)


L7RD20_9VIRU Prolyl 4-hydroxylase (trembl)


L7RD21_9VIRU Arginyl-tRNA synthetase (trembl)


L7RD22_9VIRU Sulfhydryl oxidase (trembl)


L7RD25_9VIRU Cyclophilin family protein (trembl)


L7RD26_9VIRU Divergent methyltransferase (trembl)


L7RD35_9VIRU N-acetylglucosaminyl phosphatidylinositol deacetylase (trembl)


L7RD37_9VIRU glycylpeptide N-tetradecanoyltransferase (trembl)


L7RD43_9VIRU Cytochrome b5-like protein (trembl)


L7RD44_9VIRU Glycosyltransferase GTB-type domain-containing protein (trembl)


L7RD48_9VIRU Ntn (N-terminal nucleophile) hydrolase (trembl)


L7RD52_9VIRU DNA-directed RNA polymerase subunit N (trembl)


L7RD59_9VIRU Putative resolvase (trembl)


chromosome

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.


L7RD67_9VIRU Uncharacterized protein (trembl)


L7RD69_9VIRU Endotype 6-aminohexanoat-oligomer hydrolase (trembl)


L7RD72_9VIRU Transmembrane protein (trembl)


L7RD76_9VIRU MYND-type domain-containing protein (trembl)


L7RD83_9VIRU Transmembrane protein (trembl)


L7RD84_9VIRU Myristylated IMV envelope protein (trembl)


L7RD88_9VIRU Putative RNA methylase (trembl)


L7RD90_9VIRU Arginyl-tRNA synthetase (trembl)


L7RD91_9VIRU Integral membrane protein (trembl)


L7RD92_9VIRU Glucosamine 6-phosphate N-acetyltransferase (trembl)


L7RD96_9VIRU Putative membrane protein (trembl)


L7RDA7_9VIRU Uncharacterized protein (trembl)


L7RDA8_9VIRU Cyclin-domain fused to serine-threonine kinase (trembl)


L7RDB2_9VIRU Apurinic endonuclease IV (trembl)


L7RDC0_9VIRU BTB/POZ domain-containing protein (trembl)


L7RDC8_9VIRU Mitochondrial carrier protein (trembl)


L7RDE0_9VIRU Putative ankyrin repeat protein (trembl)


L7RDE5_9VIRU Putative replication factor C small subunit (trembl)


L7RDE8_9VIRU GMC oxidoreductase (trembl)


L7RDF5_9VIRU BTB family protein (trembl)


L7RDF8_9VIRU Putative triacylglycerol lipase (trembl)


L7RDG6_9VIRU Transmembrane protein (trembl)


L7RDH5_9VIRU Metal dependent phosphohydrolase (trembl)


L7RDH7_9VIRU BTB family protein (trembl)


L7RDI7_9VIRU D6/D11-like helicase (trembl)


L7RDJ3_9VIRU Uncharacterized protein (trembl)


L7RDJ4_9VIRU BTB domain-containing protein (trembl)


L7RDJ7_9VIRU N-acetyltransferase domain-containing protein (trembl)


L7RDK4_9VIRU Alpha/beta hydrolase family protein (trembl)


L7RDL7_9VIRU Transmembrane protein (trembl)


L7RDM1_9VIRU Uncharacterized protein (trembl)


L7RDM3_9VIRU Phosphoinositide 3-kinase (trembl)


L7RDN7_9VIRU Putative ubiquitin-conjugating enzyme E2 (trembl)


L7RDP2_9VIRU Restriction endonuclease (trembl)


L7RDR4_9VIRU Putative 5' nucleotidase (trembl)


L7RDT2_9VIRU arginine--tRNA ligase (trembl)


L7RDU1_9VIRU Cyclin-domain fused to serine-threonine kinase (trembl)


L7RDW2_9VIRU Uncharacterized protein (trembl)


L7RDW5_9VIRU Exodeoxyribonuclease VII large subuni (trembl)


exodeoxyribonuclease VII activity

Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.


DNA catabolic process

The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.


exodeoxyribonuclease VII complex

An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.


L7RDY4_9VIRU GMC oxidoreductase (trembl)


L7RE36_9VIRU U-box domain-containing protein (trembl)


L7RE44_9VIRU KilA N-domain protein (trembl)


L7RFI6_9VIRU DNA topoisomerase 2 (trembl)


L7RFL6_9VIRU VWFA domain-containing protein (trembl)


RNA metabolic process

The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.


L7RFR4_9VIRU MdlB[COG1132], ABC-type multidrug transport system (trembl)


L7RFS8_9VIRU N-acetylglucosamine-1-phosphate uridyltransferase (trembl)


L7RFT0_9VIRU SMODS and SLOG-associating 2TM effector domain-containing protein (trembl)


L7RFT5_9VIRU Uncharacterized protein (trembl)


L7RFU2_9VIRU Eukaryotic peptide chain release translation termination factor 1 (trembl)


translation release factor activity

Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.


translational termination

The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).


L7RFU5_9VIRU Stage V sporulation protein K (trembl)


L7RFV2_9VIRU Protein kinase domain-containing protein (trembl)


L7RFX1_9VIRU DNA-directed RNA polymerase (trembl)


intein-mediated protein splicing

The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.


L7RFX4_9VIRU ATP-dependent Lon protease, bacterial type (trembl)


L7RFX6_9VIRU Putative site-specific integrase-resolvase (trembl)


L7RFX8_9VIRU isoleucine--tRNA ligase (trembl)


aminoacyl-tRNA editing activity

The hydrolysis of an incorrectly aminoacylated tRNA.


isoleucine-tRNA ligase activity

Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H+.


isoleucyl-tRNA aminoacylation

The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. The isoleucyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of a isoleucine-accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.


aminoacyl-tRNA metabolism involved in translational fidelity

Any process which detects an amino-acid acetylated tRNA is charged with the correct amino acid, or removes incorrect amino acids from a charged tRNA. This process can be performed by tRNA synthases, or by subsequent reactions after tRNA aminoacylation.


L7RFY5_9VIRU Uncharacterized protein (trembl)


L7RFZ3_9VIRU Uncharacterized protein (trembl)


L7RG00_9VIRU Uncharacterized protein (trembl)


L7RG05_9VIRU Cathepsin B, cystein protease (trembl)


L7RG09_9VIRU Uncharacterized protein (trembl)


L7RG10_9VIRU Eukaryotic initiation factor eIF1/SUI (trembl)


L7RG12_9VIRU E2 ubiquitin-conjugating enzyme (trembl)


L7RG13_9VIRU Uncharacterized protein (trembl)


L7RG15_9VIRU Holliday junction resolvase (trembl)


L7RG17_9VIRU Patatin-like phospholipase (trembl)


L7RG22_9VIRU Putative HD phosphohydrolase (trembl)


L7RG25_9VIRU Putative dehydrogenase (trembl)


L7RG27_9VIRU Uncharacterized protein (trembl)


L7RG28_9VIRU Poxvirus P4B major core protein (trembl)


L7RG29_9VIRU SAM-dependent methyltransferase (trembl)


L7RG33_9VIRU Putative replication factor C small subunit (trembl)


L7RG37_9VIRU Putative endonuclease of the XPG family (trembl)


L7RG39_9VIRU Phospholipase D-like domain-containing protein (trembl)


L7RG42_9VIRU Ricin B lectin domain-containing protein (trembl)


L7RG47_9VIRU Sulfhydryl oxidase (trembl)


L7RG64_9VIRU TFII-like transcription factor (trembl)


L7RG71_9VIRU Uncharacterized protein (trembl)


L7RG79_9VIRU DNA-directed DNA polymerase (trembl)


L7RG82_9VIRU DNA polymerase family X (trembl)


L7RG84_9VIRU Ribonucleoside-diphosphate reductase (trembl)


L7RG89_9VIRU Uncharacterized protein (trembl)


L7RG93_9VIRU Uncharacterized protein (trembl)


L7RGC1_9VIRU Uncharacterized protein (trembl)


L7RGC3_9VIRU Uncharacterized protein (trembl)


Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.


L7RGD5_9VIRU CDAN1-interacting nuclease 1 (trembl)


L7RGE7_9VIRU Numod4 NHN endonuclease (trembl)


L7RGE9_9VIRU Type I cysteine dioxygenase (trembl)


oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.


L7RGF5_9VIRU Uncharacterized protein (trembl)


L7RGF8_9VIRU Virion-associated membrane protein (trembl)


L7RGG1_9VIRU NAD-dependent DNA ligase (trembl)


L7RGH1_9VIRU Glycosyltransferase family 25 (trembl)


L7RGH6_9VIRU Patatin phospholipase (trembl)


L7RGJ3_9VIRU Putative transposase (trembl)


L7RGL5_9VIRU Arginyl-tRNA synthetase (trembl)


L7RGL7_9VIRU Virion-associated membrane protein (trembl)


L7RGM4_9VIRU Serine-threonine kinase (trembl)


L7RGQ5_9VIRU Protein Tyrosine Kinase (PTK) family protein (trembl)


L7RGR0_9VIRU Mitochondrial 18 kDa protein (trembl)


L7RGR2_9VIRU Uncharacterized protein (trembl)


L7RGR7_9VIRU tyrosine--tRNA ligase (trembl)


L7RGS0_9VIRU Uncharacterized protein (trembl)


L7RGS7_9VIRU Post-GPI attachment to proteins factor 3 (trembl)


L7P648_9CIRC Replication-associated protein (trembl)


M1JD72_9VIRU Nonstructural replication protein-like protein (trembl)


K7X4M6_9MONO Fusion glycoprotein F0 (trembl)


fusion of virus membrane with host plasma membrane

Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.


virion membrane

The lipid bilayer surrounding a virion.


K7XAQ7_9MONO Non-structural protein V (trembl)


suppression by virus of host type I interferon-mediated signaling pathway

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of host MDA-5 activity

Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by inhibiting the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.


modulation by symbiont of host cellular process

Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism.


K7XAQ9_9MONO RNA-directed RNA polymerase L (trembl)


structural constituent of virion

The action of a molecule that contributes to the structural integrity of a virion.


virion assembly

A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.


K7Y0L4_9MONO Attachment protein (trembl)


exo-alpha-sialidase activity

Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.


host cell surface receptor binding

Binding to a receptor on the host cell surface.


viral life cycle

A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.


virion attachment to host cell

The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.


viral entry into host cell

The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.


K7X4M8_9MONO Non-structural protein V (trembl)


K7X4N2_9MONO RNA-directed RNA polymerase L (trembl)


K7XBE1_9MONO Attachment protein (trembl)


K7XN73_9MONO Fusion glycoprotein F0 (trembl)


Q91UI8_9VIRU RNA silencing suppressor (trembl)


Q91UJ0_9VIRU Movement protein TGBp3 (trembl)


host cell endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).


host cell endoplasmic reticulum membrane

The lipid bilayer surrounding the host cell endoplasmic reticulum.


Q91UJ1_9VIRU Movement protein TGB2 (trembl)


transport of virus in host, cell to cell

The transport of a virus between adjacent cells in a multicellular organism.


mRNA methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.


mRNA methylation

The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.


A0A0U3TCD6_9VIRU Nucleocapsid protein (trembl)


A0A0U4CCN7_9VIRU RNA-directed RNA polymerase L (trembl)


G8H9D4_9VIRU Putative replicase (trembl)


A0A6G5X254_9VIRU RNA-directed RNA polymerase L (trembl)


A0A6G5X2C3_9VIRU Uncharacterized protein (trembl)


POLS_ABPVR Structural polyprotein (sprot)


POLN_ABPVR Replicase polyprotein (sprot)


K4HHN2_ARV Non-structural transmembrane glycoprotein (trembl)


endomembrane system

A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.


host cell endomembrane system

A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.


K4HIF6_ARV Virion transmembrane glycoprotein (trembl)


A0A0A7W5B8_9POLY Large T antigen (trembl)


suppression by virus of host innate immune response

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense.


disruption by virus of host JAK-STAT cascade via inhibition of JAK1 activity

Any process in which interferes with a JAK-STAT signal cascade in a host organism by reducing the activity of host JAK1 (Janus Kinase 1).


perturbation by virus of host G1/S transition checkpoint

A process in which a virus interferes with the normal execution of the host cell G1/S transition checkpoint. The host is defined as the larger of the organisms involved in a symbiotic interaction.


perturbation by virus of host cell cycle progression

A process in which a virus interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.


A0A0A7W5I1_9POLY Minor capsid protein (trembl)


A0A0A7W722_9POLY Minor capsid protein VP2 (trembl)


AAP_AAV2S Assembly activating protein AAP (sprot)


host cell nucleolus

A small, dense body one or more of which are present in the nucleus of eukaryotic host cells.


protein binding

Binding to a protein.


perturbation by virus of G2/M transition of host mitotic cell cycle

A process in which a virus interferes with the progression of the host mitotic cell cycle from G2 phase to M phase, leading to arrest in G2 phase.


permeabilization of host organelle membrane involved in viral entry into host cell

Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.


viral entry via permeabilization of inner membrane

The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabilization of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabilization of the plasma membrane.


endocytosis involved in viral entry into host cell

Any endocytosis that is involved in the uptake of a virus into a host cell.


clathrin-dependent endocytosis of virus by host cell

Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.


T=1 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.


A0A916KNR7_9POXV Uncharacterized protein (trembl)


A0A916KNR8_9POXV Uncharacterized protein (trembl)


A0A916KNT8_9POXV RING-type domain-containing protein (trembl)


A0A916KNU6_9POXV Thymidine kinase (trembl)


A0A916KNV3_9POXV VLTF-2 late transcription factor 2 (trembl)


A0A916KNV7_9POXV Ribonucleoside-diphosphate reductase small chain (trembl)


A0A916KNV8_9POXV Uncharacterized protein (trembl)


A0A916KNW2_9POXV DNA polymerase (trembl)


A0A916KNW7_9POXV Poly(A) polymerase catalytic subunit (trembl)


A0A916KNX6_9POXV mRNA decapping enzyme (Cop-D9R) (trembl)


A0A916KNY5_9POXV Uncharacterized protein (trembl)


A0A916KNY7_9POXV DNA topoisomerase (trembl)


A0A916KNY8_9POXV Entry-fusion complex protein OPG086 (trembl)


membrane fusion involved in viral entry into host cell

Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell.


A0A916KNZ0_9POXV Protein tyrosine phosphatase 2 (trembl)


A0A916KNZ1_9POXV Early transcription factor 82 kDa subunit (trembl)


positive regulation of DNA-templated transcription

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.


A0A916KNZ4_9POXV Uncharacterized protein (trembl)


A0A916KNZ5_9POXV DNA-directed RNA polymerase (trembl)


A0A916KNZ8_9POXV NTPase, DNA primase (trembl)


A0A916KP00_9POXV Uncharacterized protein (trembl)


A0A916KP01_9POXV RNA helicase NPH-II (trembl)


ribonucleoside triphosphate phosphatase activity

Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate.


A0A916KP05_9POXV Ser/thr kinase (Cop-B1R) (trembl)


A0A916KP12_9POXV Protein phosphatase 1B (trembl)


cation binding

Binding to a cation, a charged atom or group of atoms with a net positive charge.


A0A916KP14_9POXV Entry-fusion complex component, myristylprotein (trembl)


A0A916KP16_9POXV Uncharacterized protein (trembl)


A0A916KP27_9POXV Phospholipase A2-like domain-containing protein (trembl)


phospholipase A2 activity

Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospholipid + H2O = 1-acyl-sn-glycero-3-phospholipid + a fatty acid. This reaction removes the fatty acid attached to the sn2-position. Substrates include phosphatidylcholine, phosphatidylethanolamine, choline plasmalogen and phosphatides.


phospholipid metabolic process

The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.


arachidonic acid secretion

The controlled release of arachidonic acid from a cell or a tissue.


A0A916KP28_9POXV Sensor histidine kinase (trembl)


A0A916KP29_9POXV 62 kDa protein (trembl)


response to antibiotic

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.


A0A916KP31_9POXV Inhibitor of apoptosis 4 (trembl)


A0A916KP38_9POXV IMV MP/virus entry (Cop-A28L) (trembl)


viral process

A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.


A0A916KP40_9POXV Uncharacterized protein (trembl)


A0A916KP42_9POXV Entry and fusion IMV protein (Cop-L5R) (trembl)


A0A916KP45_9POXV Probable AP endonuclease (trembl)


A0A916KP48_9POXV Uncharacterized protein (trembl)


A0A916KP54_9POXV Leucine rich repeat gene family (trembl)


A0A916KP56_9POXV mRNA-capping enzyme catalytic subunit (trembl)


A0A916KP57_9POXV Viral late gene transcription factor 3 (trembl)


A0A916KP58_9POXV Uncharacterized protein (trembl)


A0A916KP59_9POXV Virion core protein 4b (trembl)


A0A916KP60_9POXV Late 16kDa membrane protein (Cop-J5L) (trembl)


A0A916KP61_9POXV glycylpeptide N-tetradecanoyltransferase (trembl)


A0A916KP62_9POXV RING-type domain-containing protein (trembl)


A0A916KP65_9POXV Uncharacterized protein (trembl)


A0A916KP66_9POXV Uncharacterized protein (trembl)


A0A916KP69_9POXV IMV membrane protein entry/fusion complex component (Cop-A21L) (trembl)


calcium ion binding

Binding to a calcium ion (Ca2+).


A0A916KP74_9POXV Viral membrane associated, early morphogenesis protein (Cop-A9L) (trembl)


A0A916KP75_9POXV P35 apoptosis inhibitor (trembl)


cysteine-type endopeptidase inhibitor activity involved in apoptotic process

Binds to and stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.


negative regulation of apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.


A0A916KP77_9POXV Uncharacterized protein (trembl)


A0A916KP78_9POXV Holliday junction resolvase (trembl)


four-way junction DNA binding

Binding to a DNA segment containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.


A0A916KP80_9POXV DNA-directed RNA polymerase 147 kDa polypeptide (trembl)


A0A916KP88_9POXV Uncharacterized protein (trembl)


A0A916KP91_9POXV Virion core cysteine protease (trembl)


A0A916KP92_9POXV Uncharacterized protein (trembl)


A0A916KP98_9POXV Methyltransferase domain-containing protein (trembl)


A0A916KPA4_9POXV N1R/p28-like protein (trembl)


A0A916KPA7_9POXV Cu/Zn superoxide dismutase (trembl)


A0A916KPB0_9POXV Leucine rich repeat gene family (trembl)


A0A916KPB2_9POXV Protein phosphatase 2C (trembl)


A0A916KPB5_9POXV Uncharacterized protein (trembl)


chitin binding

Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.


A0A916KPB7_9POXV Uncharacterized protein (trembl)


A0A916KPC0_9POXV Uncharacterized protein (trembl)


A0A916KPC5_9POXV Uncharacterized protein (trembl)


A0A916KPD1_9POXV RNA polymerase-associated transcription-specificity factor RAP94 (trembl)


DNA-templated transcription termination

The completion of transcription: the RNA polymerase pauses, the RNA-DNA hybrid dissociates, followed by the release of the RNA polymerase from its DNA template.


A0A916KPE1_9POXV Metalloprotease (Cop-G1L) (trembl)


A0A916KPG9_9POXV Myristylated protein, essential for entry/fusion (Cop-A16L) (trembl)


A0A916KPI1_9POXV Uncharacterized protein (trembl)


A0A916KPK6_9POXV Uncharacterized protein (trembl)


A0A916KPL3_9POXV Morph, VETF-s early transcription factor small (trembl)


A0A916KPM7_9POXV Uncharacterized protein (trembl)


A0A916KPN5_9POXV Uncharacterized protein (trembl)


A0A916NWN9_9POXV Early transcription factor 70 kDa subunit (trembl)


A0A916NWQ0_9POXV Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (trembl)


translation elongation factor activity

Functions in chain elongation during polypeptide synthesis at the ribosome.


Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.


translational elongation

The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.


regulation of mRNA 3'-end processing

Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.


A0A916NWS5_9POXV Cell division protein FtsL (trembl)


A0A916NWU2_9POXV Uncharacterized protein (trembl)


A0A916NWV6_9POXV Poly(A) polymerase small subunit VP39 (trembl)


A0A916NWW2_9POXV Uncharacterized protein (trembl)


A0A916NWY4_9POXV Uncharacterized protein (trembl)


A0A916NX03_9POXV Uncharacterized protein (trembl)


A0A916NX23_9POXV S-S bond formation pathway protein substrate (Cop-F9L) (trembl)


phospholipase activity

Catalysis of the hydrolysis of a glycerophospholipid.


chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.


plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.


A0A916NX88_9POXV N1R/p28-like protein (trembl)


A0A916NXD0_9POXV P35 apoptosis inhibitor (trembl)


A0A916P041_9POXV G-protein coupled receptors family 2 profile 2 domain-containing protein (trembl)


transmembrane signaling receptor activity

Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.


cell surface receptor signaling pathway

The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.


A0A916P060_9POXV Uncharacterized protein (trembl)


A0A916P069_9POXV Uncharacterized protein (trembl)


A0A916P091_9POXV dUTPase-like domain-containing protein (trembl)


A0A916P0A8_9POXV IMV membrane protein (Cop-L1R) (trembl)


A0A916P0B4_9POXV Nucleoside triphosphatase I (trembl)


A0A916P0M3_9POXV Uncharacterized protein (trembl)


A0A916P0P8_9POXV Uracil-DNA glycosylase, DNA polymerase processivity factor (trembl)


A0A916P0Q3_9POXV Reverse transcriptase domain-containing protein (trembl)


A0A916P0Q7_9POXV IMV heparin binding surface protein (trembl)


A0A916P0R3_9POXV Uncharacterized protein (trembl)


A0A916P0U8_9POXV Sulfhydryl oxidase FAD-linked (Cop-E10R) (trembl)


A0A916P0V5_9POXV Uncharacterized protein (trembl)


A0A916P0Y0_9POXV NAD-dependent DNA ligase (trembl)


A0A916P100_9POXV Serine/threonine-protein kinase 2 (trembl)


A0A916P625_9POXV Peptidase M10 metallopeptidase domain-containing protein (trembl)


A0A916P648_9POXV Uncharacterized protein (trembl)


A0A916P676_9POXV Uncharacterized protein (trembl)


A0A916P683_9POXV Uncharacterized protein (trembl)


A0A916P690_9POXV Uncharacterized protein (trembl)


A0A916P6A5_9POXV Entry-fusion complex essential component (Cop-H2R) (trembl)


Q80LH2_NPVAH Late expression factor 1 (trembl)


DNA primase activity

Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.


DNA replication, synthesis of RNA primer

The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis.


Q80LH3_NPVAH Uncharacterized protein (trembl)


Q80LH4_NPVAH Ecdysteroid UDP-glucosyltransferase (trembl)


UDP-glycosyltransferase activity

Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.


Q80LH7_NPVAH Uncharacterized protein (trembl)


Q80LI4_NPVAH Fibroblast growth factor (trembl)


Q80LI5_NPVAH Uncharacterized protein (trembl)


Q80LJ0_NPVAH Superoxide dismutase (trembl)


Q80LJ2_NPVAH Calyx/polyhedral envelope protein (trembl)


Q80LJ4_NPVAH Capsid protein P24 (trembl)


Q80LJ6_NPVAH Late expression factor 2 (trembl)


viral transcription

The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.


Q80LJ8_NPVAH Protein kinase interacting protein (trembl)


Q80LK1_NPVAH Per os infectivity factor 2 (trembl)


Q80LK3_NPVAH Uncharacterized protein (trembl)


Q80LK6_NPVAH Uncharacterized protein (trembl)


Q80LL5_NPVAH Uncharacterized protein (trembl)


Q80LL6_NPVAH Capsid protein P80 (trembl)


protein metabolic process

The chemical reactions and pathways involving a protein. Includes protein modification.


Q80LM0_NPVAH Basic DNA-binding protein P6.9 (trembl)


Q80LM1_NPVAH Late expression factor 5 (trembl)


Q80LM3_NPVAH Uncharacterized protein (trembl)


Q80LM5_NPVAH Occlusion-derived virus envelope protein E25 (trembl)


Q80LM8_NPVAH Late expression factor 4 (trembl)


Q80LM9_NPVAH Major capsid protein VP39 (trembl)


Q80LN0_NPVAH Capsid associated protein VP91 (trembl)


Q80LN5_NPVAH Very late factor 1 (trembl)


Q80LN8_NPVAH DNA-directed DNA polymerase (trembl)


Q80LP0_NPVAH Late expression factor 3 (trembl)


Q80LP2_NPVAH RrmJ-type SAM-dependent 2'-O-MTase domain-containing protein (trembl)


Q80LP6_NPVAH Occlusion-derived virus envelope protein E66 (trembl)


Q80LP7_NPVAH DNA-directed RNA polymerase (trembl)


Q80LP8_NPVAH J domain-containing protein (trembl)


Q80LR1_NPVAH Late expression factor 9 (trembl)


viral occlusion body

A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host.


2',3'-cyclic GMP-AMP binding

Binding to 2',3' cyclic GMP-AMP (cGAMP) nucleotide, a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.


Q80LR9_NPVAH Envelope protein P74 (trembl)


Q80LS3_NPVAH Occlusion-derived virus envelope protein E18 (trembl)


Q80LS5_NPVAH Chitin-binding type-2 domain-containing protein (trembl)


LEF11_NPVAH Late expression factor 11 (sprot)


Q80LT8_NPVAH Occlusion-derived virus envelope protein E56 (trembl)


Q80LU4_NPVAH Alkaline exonuclease (trembl)


Q77IS9_GVAO Ecdysteroid UDP-glucosyltransferase (trembl)


Q7T9Q5_GVAO Late expression factor 8 (trembl)


telomere maintenance

Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.


Q7T9R5_GVAO Late expression factor 9 (trembl)


Q7T9S1_GVAO DNA-directed DNA polymerase (trembl)


Q7T9S4_GVAO Very late expression factor 1 (trembl)


Q7T9T5_GVAO Late expression factor 4 (trembl)


Q7T9U2_GVAO Late expression factor 5 (trembl)


Q7T9W5_GVAO Late expression factor 11 (trembl)


extracellular matrix

A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.


Q7T9Z8_GVAO Polyhedral envelope protein-p10 (trembl)


Q7TA07_GVAO Chitin-binding protein 1 (trembl)


VP6_APRVF Microtubule-associated protein VP6 (sprot)


viral inner capsid

The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions.


host cytoskeleton

A cellular structure that forms the internal framework of eukaryotic and prokaryotic host cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.


VP5_APRVF Outer capsid protein VP5 (sprot)


viral outer capsid

The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions.


CAPSD_APRVF Putative major capsid protein VP3 (sprot)


T=2 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.


RDRP_APRVF RNA-directed RNA polymerase VP2 (sprot)


VP1_APRVF Putative structural protein VP1 (sprot)


D4QF72_APBV1 Major virion protein (trembl)


D4QF73_APBV1 Minor virion protein (trembl)


D4QF74_APBV1 Minor virion protein (trembl)


D4QF75_APBV1 Minor virion protein (trembl)


D4QF78_APBV1 Uncharacterized protein (trembl)


T2FEJ9_9POLY Minor capsid protein VP2 (trembl)


T2FFC5_9POLY Major capsid protein VP1 (trembl)


T2FFJ0_9POLY Minor capsid protein (trembl)


A0A0B5GDD0_9REOV Non-structural protein NS2 (trembl)


A0A0B5GGK4_9REOV Core protein VP4 (trembl)


A0A0B5GPD2_9REOV RNA-directed RNA polymerase (trembl)


A0A0B5GT51_9REOV Outer capsid protein VP2 (trembl)


B1PJ62_9REOV Membrane bound protein (trembl)


B4UUP0_9REOV Outer capsid protein VP5 (trembl)


adhesion of symbiont to host cell

The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.


W5ZZ53_9REOV Inner capsid protein (trembl)


A0A0N7CYV9_AHSV1 Outer capsid protein VP5 (trembl)


A0A0S1NI51_AHSV1 Core protein VP7 (trembl)


A0A0S1NI85_AHSV1 Core protein VP4 (trembl)


A0A0S1NIG4_AHSV1 Outer capsid protein VP2 (trembl)


A7WPP9_AHSV1 RNA-directed RNA polymerase (trembl)


A7WPQ7_AHSV1 Non-structural protein NS2 (trembl)


C1BEG0_9VIRU Movement protein TGB2 (trembl)


C1BEG1_9VIRU Movement protein TGBp3 (trembl)


Q8UZK2_9VIRU RNA-dependent RNA polymerase (trembl)


A0A0B5JFR5_9NIDO GP3 envelope protein (trembl)


A0A0B5JKI0_9NIDO GP4 glycoprotein (trembl)


A0A0B5JQL0_9NIDO GP5 glycosylated envelope protein (trembl)


A0A0B5JQL5_9NIDO Replicase polyprotein 1ab (trembl)


RNA nuclease activity

Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.


host cell perinuclear region of cytoplasm

The host cell cytoplasm situated near, or occurring around, the host nucleus.


A0A0B5JWP0_9NIDO GP2 glycosylated envelope protein (trembl)


A0A0B5JWP6_9NIDO Envelope protein M (trembl)


taxis

The directed movement of a motile cell or organism in response to an external stimulus.


A9JKR0_ASFPB Structural protein p22 (trembl)


A9JKW9_ASFPB Viral histone-like protein (trembl)


structural constituent of chromatin

The action of a molecule that contributes to the structural integrity of chromatin.


A9JKX1_ASFPB Thymidylate kinase (trembl)


A9JKX8_ASFPB Probable helicase A859L (trembl)


A9JKY0_ASFPB Apoptosis regulator Bcl-2 homolog (trembl)


suppression by virus of host apoptotic process

Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.


modulation by virus of host apoptotic process

Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.


regulation of apoptotic process

Any process that modulates the occurrence or rate of cell death by apoptotic process.


A9JKY6_ASFPB Ribonucleoside-diphosphate reductase small chain (trembl)


A9JKY7_ASFPB Ribonucleoside-diphosphate reductase (trembl)


A9JKZ1_ASFPB Putative helicase/primase complex protein (trembl)


A9JL02_ASFPB DNA-directed RNA polymerase subunit beta (trembl)


A9JL04_ASFPB Probable methyltransferase EP424R (trembl)


A9JL06_ASFPB Lectin-like protein EP153R (trembl)


A9JL08_ASFPB ERCC4 domain-containing protein EP364R (trembl)


cellular response to stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.


A9JL18_ASFPB Putative poly(A) polymerase catalytic subunit (trembl)


A9JL21_ASFPB RNA polymerase subunit 6 (trembl)


A9JL24_ASFPB Putative primase C962R (trembl)


A9JL27_ASFPB Sulfhydryl oxidase (trembl)


farnesyltranstransferase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.


isoprenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.


geranyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of geranyl diphosphate.


geranylgeranyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.


farnesyl diphosphate biosynthetic process

The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.


A9JL38_ASFPB Zinc finger protein B385R (trembl)


A9JL40_ASFPB Structural protein p72 (trembl)


A9JL46_ASFPB Uncharacterized protein B175L (trembl)


A9JL60_ASFPB DNA-directed RNA polymerase RPB10 homolog (trembl)


A9JL63_ASFPB Repair DNA polymerase X (trembl)


A9JL64_ASFPB Structural protein p12 (trembl)


A9JL66_ASFPB DNA-directed RNA polymerase subunit (trembl)


A9JL69_ASFPB mRNA-capping enzyme (trembl)


A9JL71_ASFPB mRNA-decapping protein g5R (trembl)


suppression by virus of host gene expression

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.


host cell rough endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface.


A9JL80_ASFPB Structural protein p17 (trembl)


A9JL82_ASFPB DNA-directed RNA polymerase RPB5 homolog (trembl)


suppression by virus of host NF-kappaB cascade

Any process in which a virus stops, prevents, or reduces a host NF-kappaB cascade.


A9JL87_ASFPB DNA topoisomerase 2 (trembl)


A9JL91_ASFPB DNA-directed RNA polymerase RPB3-11 homolog (trembl)


A9JLA3_ASFPB Serine/threonine-protein kinase 1 (trembl)


A9JLA5_ASFPB Termination factor NPH-I homolog (trembl)


A9JLB2_ASFPB Inner membrane protein p54 (trembl)


A9JLB6_ASFPB Uncharacterized protein E301R (trembl)


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity

Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host IRF3 (interferon regulatory factor-3). IRF3 is a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.


A9JLC2_ASFPB Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


dUTP diphosphatase activity

Catalysis of the reaction: dUTP + H2O = dUMP + H+ + diphosphate.


A9JLC3_ASFPB Inner membrane protein pE248R (trembl)


viral inner membrane

The lipid bilayer of a virion contained inside the protein capsid.


A9JLC6_ASFPB Probable AP endonuclease (trembl)


A9JLD4_ASFPB Transcription factor TFIIS homolog (trembl)


A9JLD8_ASFPB Transmembrane protein I329L (trembl)


A9JLE0_ASFPB Ubiquitin-conjugating enzyme E2 (trembl)


A9JLF9_ASFPB Structural protein p22 (trembl)


protein serine/threonine phosphatase inhibitor activity

Binds to and stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.


suppression by virus of host translation initiation

Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein.


D4I5E1_ASFE7 BA71V-H108R (J5R) protein (trembl)


D4I5E4_ASFE7 Serine/threonine-protein kinase 1 (trembl)


D4I5E5_ASFE7 Termination factor NPH-I homolog (trembl)


D4I5E6_ASFE7 BA71V-QP509L protein (trembl)


D4I5E9_ASFE7 Inner membrane protein p54 (trembl)


D4I5F1_ASFE7 Uncharacterized protein E301R (trembl)


D4I5F2_ASFE7 BA71V-E146L (J16L) protein (trembl)


D4I5F3_ASFE7 BA71V-E199L (J18L) protein (trembl)


D4I5F4_ASFE7 Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


D4I5F5_ASFE7 Inner membrane protein pE248R (trembl)


D4I5F7_ASFE7 Probable AP endonuclease (trembl)


D4I5G2_ASFE7 Transcription factor TFIIS homolog (trembl)


D4I5G4_ASFE7 Transmembrane protein I329L (trembl)


D4I5G5_ASFE7 Ubiquitin-conjugating enzyme E2 (trembl)


D4I5G6_ASFE7 BA71V-I177L (K14L) protein (trembl)


D4I5G9_ASFE7 MGF 360-16R protein (trembl)


D4I5I2_ASFE7 MGF 360-19R protein (trembl)


D4I5I4_ASFE7 BA71V-DP60R protein (trembl)


D4I5I6_ASFE7 BA71V-DP93R protein (trembl)


D4I5I7_ASFE7 MGF 360-2L protein (trembl)


D4I5I8_ASFE7 BA71V-KP177R protein (trembl)


D4I5J1_ASFE7 MGF 360-3L protein (trembl)


D4I5J2_ASFE7 MGF 110-1L protein (trembl)


D4I5J3_ASFE7 MGF 110-13L protein (trembl)


D4I5J5_ASFE7 MGF 110-12L protein (trembl)


D4I5J7_ASFE7 MGF 360-4L protein (trembl)


D4I5J8_ASFE7 MGF 360-6L protein (trembl)


D4I5J9_ASFE7 BA71V-X69R protein (trembl)


D4I5K0_ASFE7 MGF 300-1L protein (trembl)


D4I5K5_ASFE7 MGF 360-8L protein (trembl)


D4I5K6_ASFE7 MGF 360-9L protein (trembl)


D4I5K7_ASFE7 MGF 360-10L protein (trembl)


D4I5K8_ASFE7 MGF 360-11L protein (trembl)


D4I5L0_ASFE7 MGF 360-12L protein (trembl)


D4I5L1_ASFE7 MGF 360-13L protein (trembl)


D4I5L2_ASFE7 MGF 360-14L protein (trembl)


D4I5M2_ASFE7 Viral histone-like protein (trembl)


D4I5M4_ASFE7 BA71V-A118R protein (trembl)


D4I5M8_ASFE7 Probable helicase A859L (trembl)


D4I5M9_ASFE7 Apoptosis regulator Bcl-2 homolog (trembl)


D4I5N2_ASFE7 Ribonucleoside-diphosphate reductase small chain (trembl)


D4I5N3_ASFE7 Ribonucleoside-diphosphate reductase (trembl)


D4I5N4_ASFE7 BA71V-F165R protein (trembl)


D4I5N5_ASFE7 Putative helicase/primase complex protein (trembl)


D4I5P1_ASFE7 DNA-directed RNA polymerase subunit beta (trembl)


D4I5P2_ASFE7 BA71V-EP84R protein (trembl)


D4I5P3_ASFE7 Probable methyltransferase EP424R (trembl)


D4I5P5_ASFE7 Lectin-like protein EP153R (trembl)


D4I5P7_ASFE7 ERCC4 domain-containing protein EP364R (trembl)


D4I5Q1_ASFE7 BA71V-C84L protein (trembl)


D4I5Q2_ASFE7 BA71V-C717R protein (trembl)


D4I5Q4_ASFE7 BA71V-C257L protein (trembl)


D4I5Q5_ASFE7 Putative poly(A) polymerase catalytic subunit (trembl)


D4I5Q7_ASFE7 BA71V-C147L (G6L) protein (trembl)


D4I5R0_ASFE7 Putative primase C962R (trembl)


D4I5R1_ASFE7 BA71V-B962L protein (trembl)


D4I5R2_ASFE7 Sulfhydryl oxidase (trembl)


D4I5R5_ASFE7 BA71V-B169L protein (trembl)


D4I5R6_ASFE7 BA71V-B475L protein (trembl)


D4I5R9_ASFE7 Zinc finger protein B385R (trembl)


D4I5S0_ASFE7 BA71V-B646L (P72) protein (trembl)


D4I5S4_ASFE7 Uncharacterized protein B175L (trembl)


D4I5S8_ASFE7 BA71V-CP123L protein (trembl)


D4I5T2_ASFE7 DNA-directed RNA polymerase RPB10 homolog (trembl)


D4I5T4_ASFE7 Repair DNA polymerase X (trembl)


D4I5T5_ASFE7 BA71V-O61R (P12) protein (trembl)


D4I5T6_ASFE7 DNA-directed RNA polymerase subunit (Fragment) (trembl)


D4I5T8_ASFE7 mRNA-capping enzyme (trembl)


D4I5T9_ASFE7 mRNA-decapping protein g5R (trembl)


D4I5U4_ASFE7 BA71V-D117L (P17, i1L) protein (trembl)


D4I5U5_ASFE7 DNA-directed RNA polymerase RPB5 homolog (trembl)


D4I5U9_ASFE7 DNA topoisomerase 2 (Fragment) (trembl)


D4I5V0_ASFE7 DNA-directed RNA polymerase RPB3-11 homolog (trembl)


148R_ASFB7 Uncharacterized membrane protein EP148R (sprot)


PNG3_ASFB7 Uncharacterized membrane protein pNG3 (sprot)


PNG4_ASFB7 Uncharacterized membrane protein pNG4 (sprot)


PNG6_ASFB7 Uncharacterized membrane protein pNG6 (sprot)


modulation by virus of host process

The process in which a virus effects a change in the structure or processes of its host organism.


negative regulation of gene silencing by regulatory ncRNA

Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.


viral penetration into host nucleus

The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid.


D1GV13_9GEMI Replication enhancer (trembl)


D1GV14_9GEMI Transcriptional activator protein (trembl)


D1GV15_9GEMI Replication-associated protein (trembl)


E5AZV9_9VIRU Replication associated protein (trembl)


Q8JLM1_9GEMI Transcriptional regulator protein (trembl)


Q8JLM2_9GEMI Replication-associated protein (trembl)


Q8JLM3_9GEMI Transcriptional activator protein (trembl)


Q8JLM4_9GEMI Replication enhancer (trembl)


Q09M34_9GEMI Replication-associated protein (trembl)


Q09M35_9GEMI Transcriptional activator protein (trembl)


Q09M36_9GEMI Replication enhancer (trembl)


Q9DXI0_9GEMI Replication-associated protein (trembl)


Q9DXI1_9GEMI Transcriptional activator protein (trembl)


Q9DXI2_9GEMI Replication enhancer (trembl)


A8CFD6_9GEMI Replication enhancer (trembl)


A8CFD7_9GEMI Transcriptional activator protein (trembl)


A8CFD8_9GEMI Replication-associated protein (trembl)


B6D5S3_9ABAC Occlusion-derived virus envelope protein ODV-E56 (trembl)


B6D5S5_9ABAC Uncharacterized protein (trembl)


B6D5S6_9ABAC Envelope fusion protein (trembl)


B6D5T1_9ABAC Late expression factor-2 (trembl)


B6D5T2_9ABAC Uncharacterized protein (trembl)


B6D5T8_9ABAC Uncharacterized protein (trembl)


hydrolase activity, hydrolyzing O-glycosyl compounds

Catalysis of the hydrolysis of any O-glycosyl bond.


chitinase activity

Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.


carbohydrate metabolic process

The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.


chitin catabolic process

The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.


B6D5U5_9ABAC Protein tyrosine phosphatase-2 (trembl)


B6D5U6_9ABAC Ecdysteroid UDP-glucosyltransferase (trembl)


B6D5U9_9ABAC Uncharacterized protein (trembl)


B6D5V2_9ABAC Protein kinase interacting protein-1 (trembl)


B6D5V5_9ABAC Actin rearrangement inducing factor-1 (trembl)


B6D5V6_9ABAC Per os infectivity factor-2 (trembl)


B6D5V7_9ABAC Per os infectivity factor-1 (trembl)


B6D5V9_9ABAC Fibroblast growth factor (trembl)


growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.


signal transduction

The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.


B6D5W0_9ABAC Uncharacterized protein (trembl)


B6D5W1_9ABAC Alkaline exonuclease (trembl)


B6D5W6_9ABAC ribonucleoside-diphosphate reductase (trembl)


B6D5W8_9ABAC Polyhedral envelope protein (trembl)


B6D5X1_9ABAC Superoxide dismutase (trembl)


B6D5X3_9ABAC Per os infectivity factor-3 (trembl)


B6D5X5_9ABAC Poly (ADP-ribose) glycohydrolase (PARG) catalytic domain-containing protein (trembl)


Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.


regulation of DNA repair

Any process that modulates the frequency, rate or extent of DNA repair.


dUMP biosynthetic process

The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).


dUTP catabolic process

The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.


B6D5Y5_9ABAC Occlusion-derived virus envelope protein ODV-E66 (trembl)


B6D5Y6_9ABAC Uncharacterized protein (trembl)


B6D5Y7_9ABAC Occlusion-derived virus envelope protein ODV-EC43 (trembl)


B6D5Z4_9ABAC Late expression factor-5 (trembl)


B6D5Z6_9ABAC Viral enhancing factor-2 (trembl)


B6D5Z9_9ABAC Putative occlusion-derived envelope protein ODV-E28 (trembl)


B6D601_9ABAC Occlusion-derived virus envelope protein ODV-E25 (trembl)


B6D604_9ABAC RING-type domain-containing protein (trembl)


B6D605_9ABAC Late expression factor-4 (trembl)


B6D606_9ABAC Major capsid protein (trembl)


B6D613_9ABAC Very late expression factor-1 (trembl)


B6D616_9ABAC RrmJ-type SAM-dependent 2'-O-MTase domain-containing protein (trembl)


B6D618_9ABAC Late expression factor-3 (trembl)


B6D620_9ABAC DNA-directed DNA polymerase (trembl)


B6D627_9ABAC Late expression factor-9 (trembl)


B6D644_9ABAC DNA-directed RNA polymerase (trembl)


B6D647_9ABAC Occlusion-derived virus envelope protein ODV-E66 (trembl)


B6D652_9ABAC Late expression factor 11 (trembl)


B6D669_9ABAC Chitin-binding type-2 domain-containing protein (trembl)


B6D670_9ABAC Occlusion-derived virus envelope protein ODV-EC27 (trembl)


B6D671_9ABAC Uncharacterized protein (trembl)


B6D672_9ABAC Occlusion-derived virus envelope protein ODV-E18 (trembl)


B6D677_9ABAC Ribonucleoside-diphosphate reductase (trembl)


Q6QXF7_GVAS ribonucleoside-diphosphate reductase (trembl)


Q6QXG1_GVAS DNA-directed DNA polymerase (trembl)


Q6QXI9_GVAS Ecdysteroid UDP-glucosyltransferase (trembl)


Q6QXJ5_GVAS Late expression factor 11 (trembl)


A0A0A7KR14_9ABAC Viral cathepsin (trembl)


A0A0A7KR65_9ABAC ribonucleoside-diphosphate reductase (trembl)


A0A0A7KRA7_9ABAC DNA-directed DNA polymerase (trembl)


A0A0A7KRL3_9ABAC Ribonucleoside-diphosphate reductase (trembl)


A0A0A7KT92_9ABAC Protein kinase-1 (trembl)


A0A0A7KTA7_9ABAC Ecdysteroid UDP-glucosyltransferase (trembl)


A0A0A7KVG7_9ABAC Late expression factor 11 (trembl)


A0A0K1RL37_9CIRC Putative replication initiation protein (Fragment) (trembl)


A0A0M5L4E9_9VIRU RNA-directed RNA polymerase L (trembl)


endoplasmic reticulum-Golgi intermediate compartment

A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.


host cell endoplasmic reticulum-Golgi intermediate compartment

A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.


A8QZ16_9VIRU Envelopment polyprotein (trembl)


A0A068A9W5_9GAMA Envelope glycoprotein B (trembl)


host cell endosome

A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.


host cell endosome membrane

The lipid bilayer surrounding a host cell endosome.


A0A068A9W6_9GAMA Capsid scaffolding protein (trembl)


viral release from host cell

The dissemination of mature viral particles from a host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.


A0A068A9W7_9GAMA Envelope glycoprotein H (trembl)


A0A068A9W9_9GAMA Cytoplasmic envelopment protein 2 (trembl)


viral tegument

A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.


A0A068A9X0_9GAMA Cytoplasmic envelopment protein 3 (trembl)


viral budding from Golgi membrane

A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.


A0A068A9X1_9GAMA Portal protein (trembl)


A0A068A9X5_9GAMA Triplex capsid protein 1 (trembl)


viral capsid assembly

The assembly of a virus capsid from its protein subunits.


A0A068A9X6_9GAMA Nuclear egress protein 2 (trembl)


host cell nuclear inner membrane

The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.


intracellular transport of virus

The directed movement of a virus, or part of a virus, within the host cell.


host cell

A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.


A0A068AAJ8_9GAMA Capsid vertex component 2 (trembl)


viral genome packaging

The encapsulation of the viral genome within the capsid.


A0A068AAK0_9GAMA DNA polymerase (trembl)


A0A068AAK9_9GAMA Tripartite terminase subunit 3 (trembl)


A0A068AAL4_9GAMA Envelope glycoprotein M (trembl)


A0A068AAL7_9GAMA DNA replication helicase (trembl)


bidirectional double-stranded viral DNA replication

A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.


A0A068AAL8_9GAMA Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


dUTP metabolic process

The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.


A0A068AAM4_9GAMA Large tegument protein deneddylase (trembl)


modulation by symbiont of host protein ubiquitination

Any process by which a symbiont increases or decreases ubiquitination of target proteins of a host organism.


A0A068AAM7_9GAMA Packaging protein UL32 (trembl)


A0A068AAN1_9GAMA Tripartite terminase subunit 2 (trembl)


viral DNA genome packaging

The packing of viral DNA into a capsid.


semaphorin receptor binding

Binding to a semaphorin receptor.


A0A068ABP1_9GAMA Tripartite terminase subunit 1 (trembl)


protein processing

Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.


A0A068ABQ0_9GAMA Thymidine kinase (trembl)


TMP biosynthetic process

The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.


A0A068ABQ3_9GAMA Triplex capsid protein 2 (trembl)


A0A068ABQ7_9GAMA Capsid vertex component 1 (trembl)


A0A068ABR2_9GAMA Shutoff alkaline exonuclease (trembl)


induction by virus of catabolism of host mRNA

The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA).


A0A068ABR6_9GAMA Cytoplasmic envelopment protein 1 (trembl)


A0A068ABR9_9GAMA Envelope glycoprotein L (trembl)


A0A068ABT4_9GAMA Ribonucleoside-diphosphate reductase large subunit (trembl)


A0A068ADB3_9GAMA Major DNA-binding protein (trembl)


single-stranded DNA binding

Binding to single-stranded DNA.


A0A068ADD0_9GAMA Major capsid protein (trembl)


T=16 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres.


A0A068ADF3_9GAMA Uracil-DNA glycosylase (trembl)


A0A068ADH0_9GAMA Ribonucleoside-diphosphate reductase small subunit (trembl)


deoxyribonucleoside diphosphate metabolic process

The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.


A0A068ADH6_9GAMA Small capsomere-interacting protein (trembl)


A0A068ADI3_9GAMA Nuclear egress protein 1 (trembl)


viral budding from nuclear membrane

A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.


exit of virus from host cell nucleus by nuclear egress

The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.


VGA4_ALHV1 Uncharacterized gene A4 protein (sprot)


DNBI_ALHV1 Major DNA-binding protein (sprot)


TRM1_ALHV1 Tripartite terminase subunit 1 (sprot)


GB_ALHV1 Envelope glycoprotein B (sprot)


DPOL_ALHV1 DNA polymerase catalytic subunit (sprot)


VGA5_ALHV1 G-protein coupled receptor A5 (sprot)


G protein-coupled receptor activity

Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


G protein-coupled receptor signaling pathway

The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane.


SCAF_ALHV1 Capsid scaffolding protein (sprot)


CVC2_ALHV1 Capsid vertex component 2 (sprot)


GH_ALHV1 Envelope glycoprotein H (sprot)


TRX2_ALHV1 Triplex capsid protein 2 (sprot)


VG27_ALHV1 Uncharacterized gene 27 protein (sprot)


TRM3_ALHV1 Tripartite terminase subunit 3 (sprot)


CVC1_ALHV1 Capsid vertex component 1 (sprot)


CEP2_ALHV1 Cytoplasmic envelopment protein 2 (sprot)


VG36_ALHV1 Putative tyrosine kinase 36 (sprot)


protein tyrosine kinase activity

Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.


non-membrane spanning protein tyrosine kinase activity

Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.


AN_ALHV1 Shutoff alkaline exonuclease (sprot)


CEP3_ALHV1 Cytoplasmic envelopment protein 3 (sprot)


GM_ALHV1 Envelope glycoprotein M (sprot)


VG40_ALHV1 Uncharacterized gene 40 protein (sprot)


CEP1_ALHV1 Cytoplasmic envelopment protein 1 (sprot)


HELI_ALHV1 DNA replication helicase (sprot)


UNG_ALHV1 Uracil-DNA glycosylase (sprot)


GL_ALHV1 Envelope glycoprotein L (sprot)


BRLF1_ALHV1 Putative transcription activator BRLF1 homolog (sprot)


VGA7_ALHV1 Putative C-type lectin protein A7 (sprot)


VGA8_ALHV1 Uncharacterized gene A8 protein (sprot)


GN_ALHV1 Envelope glycoprotein N (sprot)


DUT_ALHV1 Deoxyuridine 5'-triphosphate nucleotidohydrolase (sprot)


TEG7_ALHV1 Tegument protein UL51 homolog (sprot)


IE63_ALHV1 Immediate-early phosphoprotein 57 (sprot)


VG59_ALHV1 DNA polymerase processivity factor (sprot)


RIR2_ALHV1 Ribonucleoside-diphosphate reductase small subunit (sprot)


viral latency

The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.


release from viral latency

The process by which a virus begins to replicate following a latency replication decision (switch).


RIR1_ALHV1 Ribonucleoside-diphosphate reductase large subunit (sprot)


TRX1_ALHV1 Triplex capsid protein 1 (sprot)


ITP_ALHV1 Inner tegument protein (sprot)


microtubule-dependent intracellular transport of viral material towards cell periphery

The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.


LTP_ALHV1 Large tegument protein deneddylase (sprot)


SCP_ALHV1 Small capsomere-interacting protein (sprot)


UL49_ALHV1 Uncharacterized gene 66 protein (sprot)


NEC2_ALHV1 Nuclear egress protein 2 (sprot)


TRM2_ALHV1 Tripartite terminase subunit 2 (sprot)


UL32_ALHV1 Packaging protein UL32 homolog (sprot)


NEC1_ALHV1 Nuclear egress protein 1 (sprot)


VP75_ALHV1 Probable membrane antigen 75 (sprot)


VGA9_ALHV1 Putative apoptosis regulator A9 (sprot)


VGA10_ALHV1 Uncharacterized gene A10 protein (sprot)


VGA2_ALHV1 Uncharacterized protein A2 (sprot)


VP03_ALHV1 Probable tegument protein antigen 3 (sprot)


SEMA_ALHV1 Semaphorin-like protein A3 (sprot)


A0A0N9M4N8_9VIRU Envelopment polyprotein (trembl)


fusion of virus membrane with host endosome membrane

Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell.


A0A0N9MMM4_9VIRU RNA-directed RNA polymerase L (trembl)


MEM_GOGV Putative membrane protein (sprot)


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of IKBKE activity

Any process in which a virus stops, prevents, or reduces a host viral-induced cytoplasmic pattern recognition receptor signaling pathway by reducing the activity of host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).


L_GOGV RNA-directed RNA polymerase L (sprot)


cap snatching

A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.


A0A0C5GVW6_9VIRU Capsid protein (trembl)


A0A0C5GWS6_9VIRU Movement protein TGBp3 (trembl)


A0A0C5H7M3_9VIRU RNA-dependent RNA polymerase (trembl)


Q913Z7_9VIRU Movement protein TGB2 (trembl)


A0A0K0PRX7_9GEMI Replication-associated protein (trembl)


A0A0K0PSZ7_9GEMI Replication-associated protein (trembl)


T=3 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.


host cell junction

A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.


host cell plasmodesma

A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.


X2C677_9GEMI Transcriptional activator protein (trembl)


X2C6Y5_9GEMI Replication-associated protein (trembl)


X2C8Y6_9GEMI Replication enhancer (trembl)


A0A2H5MI89_9VIRU RNA-directed RNA polymerase (trembl)


C0L9E1_9VIRU RNA replication protein (trembl)


C0L9E4_9VIRU Movement protein TGBp3 (trembl)


A0A024A1N5_9RHAB Virion transmembrane glycoprotein G (trembl)


protein domain specific binding

Binding to a specific domain of a protein.


A0A140CBZ9_9PAPI Regulatory protein E2 (trembl)


A0A140CC01_9PAPI Minor capsid protein L2 (trembl)


microtubule-dependent intracellular transport of viral material towards nucleus

The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.


transport of viral material towards nucleus

The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane.


A0A140CC02_9PAPI Major capsid protein L1 (trembl)


T=7 icosahedral viral capsid

The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.


A0A140CC05_9PAPI Replication protein E1 (trembl)


Q65A77_9VIRU RNA-directed RNA polymerase (trembl)


Q65A78_9VIRU Putative coat protein (trembl)


A0A0U1UZ37_9ALPC Spike glycoprotein (trembl)


receptor-mediated virion attachment to host cell

The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.


A0A0U1WHF8_9ALPC Membrane protein (trembl)


A0A0U1WHG4_9ALPC ORF1ab polyprotein (trembl)


3'-5'-RNA exonuclease activity

Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.


RNA exonuclease activity

Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.


omega peptidase activity

Catalysis of the cleavage of non-standard peptide bonds releasing substituted amino acids such as pyroglutamate or cleave isopeptide bonds, such as many deubiquitinating enzymes.


induction by virus of host autophagy

Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.


A0A0U1WHG6_9ALPC Uncharacterized protein (trembl)


A0A0U1WJX0_9ALPC Small envelope protein (trembl)


pore formation by virus in membrane of host cell

The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism.


A0A166MMH2_9PAPI Regulatory protein E2 (trembl)


PDZ domain binding

Binding to a PDZ domain of a protein, a domain found in diverse signaling proteins.


A0A166MNN5_9PAPI Replication protein E1 (trembl)


A0A166MNQ4_9PAPI Minor capsid protein L2 (trembl)


A0A166MNR6_9PAPI Major capsid protein L1 (trembl)


A0A6G9LUF7_9POLY Minor capsid protein VP2 (trembl)


A0A6G9LUG9_9POLY Large T antigen (trembl)


A0A6G9LWU8_9POLY Small T antigen (trembl)


A0A6G9LXA2_9POLY Viral protein 1 (trembl)


A0A5J6XVL7_9POLY Middle T antigen (trembl)


K7QJJ1_9POLY Capsid protein VP1 (trembl)


K7QKH3_9POLY Minor capsid protein (trembl)


Q3V6G4_9VIRU Movement protein TGBp3 (trembl)


Q3V6G5_9VIRU Triple gene block protein 2 (trembl)


Q3V6G6_9VIRU Triple gene block protein 1 (trembl)


Q3V6G7_9VIRU RNA replication protein (trembl)


Q2TJB0_9VIRU Triple gene block 1 protein 26k (trembl)


Q2TJB1_9VIRU RNA replication protein (trembl)


Q52Z67_9VIRU Movement protein TGBp3 (trembl)


Q4GZI5_9GEMI Replication-associated protein (trembl)


Q4GZI6_9GEMI Transcriptional activator protein (trembl)


Q4GZI7_9GEMI Replication enhancer (trembl)


A9CQL6_9VIRU RNA-directed RNA polymerase (trembl)


host cell cytoplasmic vesicle

A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.


A0A076L0Y3_9VIRU RNA-dependent RNA polymerase (trembl)


Q65A75_9VIRU RNA-dependent RNA polymerase (trembl)


Q65A76_9VIRU Putative coat protein (trembl)


I7GUN6_9BROM Replication protein 1a (trembl)


I7HHJ1_9BROM RNA-directed RNA polymerase 2a (trembl)


V5V0U1_9VIRU Putative triple gene block protein 1 (trembl)


V5V1N5_9VIRU Movement protein TGBp3 (trembl)


V5V1R1_9VIRU RNA replication protein (trembl)


V5V1S7_9VIRU Putative triple gene block protein 2 (trembl)


V5V388_9VIRU Putative coat protein (trembl)


A0A0U2HZR0_9VIRU Putative NTPase (trembl)


A0A0U2JD16_9VIRU Major capsid protein (trembl)


A0A0U2JDP8_9VIRU Transmembrane protein (trembl)


A0A0U2JP15_9VIRU IMV membrane protein (trembl)


A0A0U2JPS1_9VIRU dUTP diphosphatase (trembl)


A0A0U2K4Q0_9VIRU Neurofilament triplet H1-like protein (trembl)


A0A0U2K4U5_9VIRU Orf20-like protein (trembl)


A0A0U2K695_9VIRU Uncharacterized protein (trembl)


A0A0U2K6G7_9VIRU ElF2a-like protein (trembl)


A0A0U2Q8X2_9VIRU Cytosine DNA methyltransferase (trembl)


A0A0U2QAJ0_9VIRU Putative LITAF/PIG7 membrane-associated motif in LPS-induced tumor necrosis factor alpha factor (trembl)


A0A0U2QB90_9VIRU L-protein-like protein (trembl)


A0A0U2QD11_9VIRU Transmembrane protein (trembl)


A0A0U2QD42_9VIRU ribonucleoside-diphosphate reductase (trembl)


A0A0U2QFB5_9VIRU Transmembrane protein (trembl)


A0A0U2QHL9_9VIRU Putative tyrosine kinase (trembl)


A0A0U2QI73_9VIRU Putative phosphotransferase (trembl)


A0A0U2R6L5_9VIRU Uncharacterized protein (trembl)


A0A0U2R6P5_9VIRU Putative D5 family NTPase/ATPase (trembl)


A0A0U2R7T3_9VIRU Putative myeloid cell leukemia protein (trembl)


A0A0U2RDY1_9VIRU Transmembrane protein (trembl)


A0A0U2RDZ5_9VIRU Putative hydrolase of the metallo-beta-lactamase superfamily (trembl)


A0A0U2RE09_9VIRU Protein kinase domain-containing protein (trembl)


A0A0U2RGH4_9VIRU Holliday junction resolvase (trembl)


A0A0U2RGT0_9VIRU Putative deoxynucleoside kinase (trembl)


deoxynucleoside kinase activity

Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.


A0A0U2RGW3_9VIRU Transmembrane protein (trembl)


A0A0U2RNN4_9VIRU Transcription elongation factor II (trembl)


A0A0U2RNW3_9VIRU Putative myristylated membrane protein (trembl)


A0A0U2RP96_9VIRU Sulfhydryl oxidase (trembl)


A0A0U2RPC8_9VIRU Helicase-like protein (trembl)


A0A0U2RPH2_9VIRU Putative replicating factor (trembl)


A0A0U2RQ57_9VIRU DNA-directed RNA polymerase subunit beta (trembl)


A0A0U2RR20_9VIRU Putative DNA repair protein RAD2 (trembl)


A0A0U2RTZ9_9VIRU Putative ATPase-dependent protease (trembl)


A0A0U2RU13_9VIRU DNA-directed DNA polymerase (trembl)


A0A0U2RUR7_9VIRU p8.141C-like protein (trembl)


A0A0U2RVD0_9VIRU Uncharacterized protein (trembl)


A0A0U2S082_9VIRU DNA-directed RNA polymerase subunit (trembl)


A0A0U2S0A0_9VIRU thymidylate synthase (trembl)


U3LXW9_9RHAB RNA-directed RNA polymerase L (trembl)


I1W5T2_9VIRU Putative viral replicase (trembl)


I1W5T3_9VIRU Triple gene block protein 1 (trembl)


I1W5T4_9VIRU Movement protein TGB2 (trembl)


I1W5T5_9VIRU Movement protein TGBp3 (trembl)


I1W5T7_9VIRU RNA silencing suppressor (trembl)


Q997A3_9BROM RNA-directed RNA polymerase 2a (trembl)


positive stranded viral RNA replication

A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.


Q997A4_9BROM Replication protein 1a (trembl)


NTP1_AMEPV Nucleoside triphosphatase I (sprot)


A28_AMEPV Envelope protein A28 homolog (sprot)


I7_AMEPV Core protease I7 homolog (sprot)


P87507_AMEPV DNA topoisomerase I (trembl)


Q9EMH5_AMEPV Uracil-DNA glycosylase (trembl)


Q9EMI5_AMEPV DNA-directed RNA polymerase 147 kDa polypeptide (trembl)


NMT_AMEPV Putative glycylpeptide N-tetradecanoyltransferase (sprot)


Q9EMJ6_AMEPV Probable AP endonuclease (trembl)


Q9EMK1_AMEPV Viral late gene transcription factor 3 (trembl)


Q9EMP6_AMEPV Serine/threonine-protein kinase (trembl)


Q9EMQ2_AMEPV Virion core protein 4b (trembl)


Q9EMR4_AMEPV mRNA-capping enzyme catalytic subunit (trembl)


ABC-type transporter activity

Primary active transporter characterized by two nucleotide-binding domains and two transmembrane domains. Uses the energy generated from ATP hydrolysis to drive the transport of a substance across a membrane.


transmembrane transport

The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.


Q9EMT4_AMEPV Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (trembl)


Q9EMT5_AMEPV Sulfhydryl oxidase (trembl)


Q9EMU4_AMEPV Early transcription factor 82 kDa subunit (trembl)


Q9EMW8_AMEPV RNA helicase NPH-II (trembl)


PTPH_AMEPV Putative tyrosine-protein phosphatase AMV078 (sprot)


Q9EMX8_AMEPV Entry-fusion complex protein OPG086 (trembl)


Q9EMY3_AMEPV DNA-directed RNA polymerase (trembl)


Q9EMY9_AMEPV Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (trembl)


Q9EMZ5_AMEPV RNA polymerase-associated transcription-specificity factor RAP94 (trembl)


Q9EN10_AMEPV Poly(A) polymerase catalytic subunit (trembl)


Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine.


cellular biosynthetic process

The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.


organic substance biosynthetic process

The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.


Q9EN44_AMEPV Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


nicotinamide riboside transmembrane transporter activity

Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.


nicotinamide riboside transport

The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


A0A076L0K3_9MONO Cysteine-rich protein V (trembl)


A0A076L0K8_9MONO RNA-directed RNA polymerase L (trembl)


A0A076L152_9MONO Hemagglutinin-neuraminidase protein HN (trembl)


A0A076L670_9MONO Matrix protein (trembl)


A0A076L8G4_9MONO Fusion glycoprotein F0 (trembl)


A1YZN4_9ALPH Tegument/envelope protein (trembl)


A1YZN7_9ALPH Tripartite terminase subunit 2 (trembl)


A1YZN8_9ALPH Nuclear egress protein 2 (trembl)


A2TIU6_9ALPH Capsid vertex component 1 (trembl)


A2TIU8_9ALPH Triplex capsid protein 2 (trembl)


A2TIV0_9ALPH Envelope protein UL20 (trembl)


host cell nuclear membrane

Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.


A2TIV6_9ALPH Small capsomere-interacting protein (trembl)


A2TIV8_9ALPH Capsid scaffolding protein (trembl)


A2TIW0_9ALPH Envelope glycoprotein B (trembl)


A3RMA2_9ALPH DNA helicase/primase complex-associated protein (trembl)


A3RMA4_9ALPH Envelope glycoprotein M (trembl)


A3RMA5_9ALPH Envelope glycoprotein L (trembl)


A3RMB2_9ALPH Cytoplasmic envelopment protein 1 (trembl)


A4GRI5_9ALPH Cytoplasmic envelopment protein 2 (trembl)


A4GRJ3_9ALPH Envelope glycoprotein H (trembl)


A4GRJ6_9ALPH Capsid vertex component 2 (trembl)


A4GRK2_9ALPH Nuclear egress protein 1 (trembl)


A4GRK3_9ALPH Packaging protein UL32 (trembl)


A4ZX80_9ALPH Tegument protein VP22 (trembl)


A4ZX81_9ALPH Envelope glycoprotein (trembl)


A4ZX82_9ALPH Deoxyuridine 5'-triphosphate nucleotidohydrolase (trembl)


A5A413_9ALPH Tegument serine/threonine protein kinase (trembl)


A5A414_9ALPH Tegument protein UL14 (trembl)


A5A417_9ALPH Regulatory protein US1 (trembl)


regulation of gene expression

Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


A7L873_9ALPH Tegument protein UL51 (trembl)


A9QXU7_9ALPH Envelope glycoprotein K (trembl)


fusion of viral membrane with host outer nuclear membrane

Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.


positive regulation of syncytium formation by virus

The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.


host cell nuclear matrix

The dense fibrillar network lying on the inner side of the host nuclear membrane.


B4XS31_9ALPH Envelope glycoprotein D (trembl)


B5LRM7_9ALPH Uracil-DNA glycosylase (trembl)


B6E8Y9_9ALPH Tegument protein UL37 (trembl)


B6E8Z0_9ALPH Triplex capsid protein 1 (trembl)


B6E8Z2_9ALPH Ribonucleoside-diphosphate reductase small subunit (trembl)


deNEDDylase activity

An isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.


C6ZD01_9ALPH DNA polymerase processivity factor (trembl)


C6ZD04_9ALPH Ribonucleoside-diphosphate reductase large subunit (trembl)


C6ZD24_9ALPH Major capsid protein (trembl)


C6ZD35_9ALPH Replication origin-binding protein (trembl)


C6ZD38_9ALPH Envelope glycoprotein E (trembl)


anchoring junction

A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.


E1U2A6_9ALPH Envelope glycoprotein I (trembl)


E1U2B0_9ALPH Multifunctional expression regulator (trembl)


E6Y393_9ALPH DNA replication helicase (trembl)


E6Y398_9ALPH Tegument protein UL47 (trembl)


E6Y399_9ALPH Alpha trans-inducing protein (trembl)


H9DUZ2_9ALPH Virion host shutoff protein (trembl)


H9DV04_9ALPH Major DNA-binding protein (trembl)


H9DV05_9ALPH Tripartite terminase subunit 1 (trembl)


H9DV17_9ALPH Tripartite terminase subunit 3 (trembl)


L_ANDV RNA-directed RNA polymerase L (sprot)


disruption by virus of host TRAF-mediated signal transduction

A process in which a virus interferes with, inhibits or stops TRAF-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity

Any process in which a virus stops, prevents, or reduces a viral-induced cytoplasmic pattern recognition receptor signaling pathway in a host organism by reducing the activity of host MAVS (mitochondrial antiviral signaling protein). MAVS is a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.


host cell surface

The external part of the host cell wall and/or host plasma membrane.


A0A088SG43_9GEMI Transcriptional activator protein (trembl)


A0A088SGC3_9GEMI Replication-associated protein (trembl)


A0A088SGJ4_9GEMI Capsid protein (trembl)


A0A088T1G4_9GEMI Replication enhancer (trembl)


A0A140GL60_9VIRU Virion-associated protein (trembl)


A0A140GL62_9VIRU Enzymatic polyprotein (trembl)


RNA-directed DNA polymerase activity

Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.


aspartic-type endopeptidase activity

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.


RNA-templated DNA biosynthetic process

A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.


A0A140GL63_9VIRU Transactivator/viroplasmin protein (trembl)


Q2Q474_9TOMB RNA-directed RNA polymerase (trembl)


W5RNT1_9CIRC Replication-associated protein (trembl)


H6U321_9VIRU RNA-directed RNA polymerase L (trembl)


H6U322_9VIRU Envelopment polyprotein (trembl)


W6JIK4_9POXV Uncharacterized protein (trembl)


W6JIL4_9POXV Nicotinamide riboside kinase 1 (trembl)


W6JIL6_9POXV Uncharacterized protein (trembl)


W6JIM7_9POXV Putative membrane protein (trembl)


W6JIP4_9POXV Putative calcium binding protein (trembl)


W6JIQ1_9POXV IMV membrane protein (trembl)


W6JIR8_9POXV Putative late transcription factor VLTF-2 (trembl)


W6JIS3_9POXV Protein kinase domain containing protein (trembl)


W6JIS6_9POXV Holliday junction resolvase (trembl)


W6JIS7_9POXV Putative core protein (trembl)


W6JIT4_9POXV Superoxide dismutase (trembl)


W6JIT6_9POXV Putative myristylated membrane protein (trembl)


W6JIT8_9POXV Uncharacterized protein (trembl)


W6JIT9_9POXV Uncharacterized protein (trembl)


W6JIU0_9POXV Tryptophan-rich sensory protein (trembl)


W6JIU3_9POXV Uncharacterized protein (trembl)


W6JIU5_9POXV Precursor p4a of core protein 4a (trembl)


W6JIU6_9POXV Putative glycosyl transferase (trembl)


W6JIU7_9POXV DNA helicase, transcriptional elongation (trembl)


W6JIV1_9POXV Reverse transcriptase (trembl)


W6JIV2_9POXV Serin/threonine kinase like (trembl)


W6JIV8_9POXV Zinc-dependent metalloprotease (trembl)


W6JIW0_9POXV Serine/threonine-protein kinase 2 (trembl)


W6JIW3_9POXV Putative viral membrane protein (trembl)


W6JIW7_9POXV Triacylglycerol lipase (trembl)


W6JIW8_9POXV Putative NTP pyrophosphohydrolase mutT motif (trembl)


W6JIX0_9POXV Uncharacterized protein (trembl)


W6JIX9_9POXV Uncharacterized protein (trembl)


W6JIY5_9POXV Capcid protein VP1-like (trembl)


W6JIZ0_9POXV S-S bond formation pathway protein (trembl)


W6JIZ4_9POXV Putative glycoprotein B (trembl)


W6JIZ6_9POXV Early transcription factor 82 kDa subunit (trembl)


W6JJ01_9POXV Late transcription factor VLTF-3 (trembl)


W6JJ15_9POXV Probable AP endonuclease (trembl)


W6JJ19_9POXV Uncharacterized protein (trembl)


W6JJ26_9POXV Uncharacterized protein (trembl)


W6JJ39_9POXV Putative exonuclease RNase T and DNA polymerase III (trembl)


W6JKS0_9POXV Matrix metalloproteinase (trembl)


W6JKT0_9POXV Putative ATP-binding cassette transporter (trembl)


W6JKU0_9POXV IMV membrane protein involved in fusion and entry (trembl)


W6JKU5_9POXV Uncharacterized protein (trembl)


W6JKV6_9POXV Uncharacterized protein (trembl)


W6JKY2_9POXV DNA-directed RNA polymerase (trembl)


W6JKY5_9POXV IMV membrane protein (trembl)


W6JKZ1_9POXV Uncharacterized protein (trembl)


W6JKZ5_9POXV Putative early transcription factor small subunit (trembl)


W6JKZ6_9POXV Putative ser/thr protein kinase (trembl)


W6JKZ9_9POXV G-protein coupled receptor Mth2-like (trembl)


W6JL01_9POXV Uncharacterized protein (trembl)


W6JL07_9POXV mRNA-capping enzyme catalytic subunit (trembl)


W6JL13_9POXV RNA polymerase-associated transcription-specificity factor RAP94 (trembl)


W6JL18_9POXV Ubiquitin/ribosomal protein (trembl)


ribosome

An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.


W6JL25_9POXV RNA helicase NPH-II (trembl)


W6JL30_9POXV Putative poly(A) polymerase small subunit (trembl)


W6JL37_9POXV DNA-directed RNA polymerase beta chain (trembl)


W6JL47_9POXV Peritrophin-A domain containing protein (trembl)


W6JL61_9POXV Entry-fusion complex protein OPG086 (trembl)


W6JL64_9POXV DNA-directed RNA polymerase 147 kDa polypeptide (trembl)


W6JL71_9POXV Zinc-dependent metalloprotease (trembl)


W6JL79_9POXV Uncharacterized protein (trembl)


W6JL81_9POXV Uncharacterized protein (trembl)


W6JL83_9POXV Phosphatidic acid phosphatase type 2 (trembl)


W6JLB2_9POXV Poxvirus myristoylprotein (trembl)


W6JLC2_9POXV Putative myristylated membrane protein (trembl)


W6JLD1_9POXV Translation elongation factor eEF-3 like (trembl)


W6JLD5_9POXV Uncharacterized protein (trembl)


W6JLG4_9POXV Putative NAD+ dependent DNA ligase (trembl)


W6JLH1_9POXV Cation transport ATPase (trembl)


W6JLH5_9POXV Uncharacterized protein (trembl)


W6JLI2_9POXV Translation initiation factor elF-4e (trembl)


W6JLI8_9POXV Uncharacterized protein (trembl)


W6JLJ1_9POXV Virion core protein 4b (trembl)


W6JLK0_9POXV Poly(A) polymerase catalytic subunit (trembl)


W6JLK9_9POXV Ubiquitin-conjugating enzyme E2 (trembl)


W6JLL8_9POXV PPM-type phosphatase domain-containing protein (trembl)


W6JLM1_9POXV Uncharacterized protein (trembl)


W6JLM5_9POXV Putative NTPase/helicase (trembl)


W6JLN7_9POXV glycylpeptide N-tetradecanoyltransferase (trembl)


W6JLQ8_9POXV Zinc-dependent metalloprotease (trembl)


W6JPJ3_9POXV Uncharacterized protein (trembl)


W6JPJ7_9POXV Uracil-DNA glycosylase (trembl)


W6JPJ9_9POXV Putative mRNA capping enzyme small subunit (trembl)


W6JPK2_9POXV Uncharacterized protein (trembl)


W6JPK4_9POXV Nucleoside triphosphatase I (trembl)


W6JPK8_9POXV 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (trembl)


W6JPK9_9POXV Uncharacterized protein (trembl)


W6JPL0_9POXV Virion membrane protein (trembl)


W6JPL4_9POXV Endonuclease/exonuclease/phosphatase domain-containing protein (trembl)


W6JPL5_9POXV Uncharacterized protein (trembl)


W6JPL7_9POXV Uncharacterized protein (trembl)


W6JPM1_9POXV Uncharacterized protein (trembl)


W6JPM3_9POXV Uncharacterized protein (trembl)


W6JPM4_9POXV ATP-dependent DNA ligase (trembl)


W6JPM5_9POXV Nucleopolyhedrovirus p26 protein (trembl)


W6JPM6_9POXV Putative vaccinia G1L metaloprotease (trembl)


W6JPM9_9POXV Uncharacterized protein (trembl)


W6JPN2_9POXV Uncharacterized protein (trembl)


W6JPN3_9POXV Uncharacterized protein (trembl)


W6JPN4_9POXV Gamma-glutamyl cyclotransferase like (trembl)


W6JPN8_9POXV Peptidase M10 metallopeptidase domain-containing protein (trembl)


W8QE04_9VIRU Uncharacterized protein (trembl)


W8QE16_9VIRU DNA-directed RNA polymerase (trembl)


W8QE20_9VIRU Membrane-type matrix metallopeptidase-1 (trembl)


W8QE39_9VIRU Type III restriction enzyme, res subunit:DEAD/DEAH box helicase, N-terminal (trembl)


W8QE45_9VIRU Lipid membrane protein (trembl)


W8QE57_9VIRU ribonucleoside-diphosphate reductase (trembl)


W8QE71_9VIRU RuvC-like Holliday junction resolvase (trembl)


W8QE83_9VIRU 5'-3' exoribonuclease 1 (trembl)


W8QE87_9VIRU Resolvase HTH domain-containing protein (trembl)


W8QEY7_9VIRU C3H1-type domain-containing protein (trembl)


W8QF03_9VIRU Putative tyrosine protein kinase (trembl)


W8QF08_9VIRU Ribonucleoside-diphosphate reductase large subunit (trembl)


W8QF12_9VIRU DNA-directed DNA polymerase (trembl)


W8QF27_9VIRU Transcription factor TFIIB cyclin-like domain-containing protein (trembl)


W8QF41_9VIRU Uncharacterized protein (trembl)


W8QF60_9VIRU DNA ligase (NAD(+)) (trembl)


W8QF75_9VIRU DNA repair exonuclease SbcCD D subunit (trembl)


W8QMX2_9VIRU Uncharacterized protein (trembl)


W8QMY0_9VIRU OTU domain-containing protein (trembl)