intestinal lipid catabolic process

The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.


double-strand break repair via homologous recombination

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein.


Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid.


apigenin-7,4'-dimethyl ether 6-hydroxylase activity

Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP.


Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.


glutathione transmembrane transporter activity

Enables the transfer of glutathione, the tripeptide glutamylcysteinylglycine, from one side of a membrane to the other.


regulation of cardiac muscle adaptation

Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.


eriodictyol 2-hydroxylase activity

Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O.


allantoinase activity

Catalysis of the reaction: allantoin + H2O = allantoate.


peptidyl-threonine decanoylation

The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.


luteinizing hormone signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Entity biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A G protein-coupled receptor signaling pathway initiated by luteinizing hormone binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process.


MHC class Ib protein complex assembly

The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules.


spermidine:coumaroyl CoA N-acyltransferase activity

Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.


coenzyme F420 binding

Binding to F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.


glycerol-3-phosphate transmembrane transporter activity

Enables the transfer of glycerol-3-phosphate from one side of a membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.


wall teichoic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


positive regulation of renal sodium excretion by pressure natriuresis

An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.


methionine racemase activity

Catalysis of the reaction: L-methionine = D-methionine.


regulation of membrane repolarization during action potential

Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.


flower formation

The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.


(S)-usnate reductase activity

Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD+ = (S)-usnate + 2 H+ + NADH.


T cell homeostasis

The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.


Catalysis of the reaction: H2O + an N-acetyl-beta-D-galactosalaminyl-[glycan] = N-acetyl-beta-D-galactosamine + a glycan.


GMP catabolic process

The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.


collecting lymphatic vessel constriction

A decrease in the diameter of collecting lymphatic vessels.


collagen binding

Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).


CCC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CCC codon.


histone H2A acetylation

The modification of histone H2A by the addition of an acetyl group.


thiamine-containing compound metabolic process

The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.


4-hydroxyphenylacetate transmembrane transporter activity

Enables the transfer of 4-hydroxyphenylacetate from one side of a membrane to the other.


lung morphogenesis

The process in which the anatomical structures of the lung are generated and organized.


negative regulation of fibronectin-dependent thymocyte migration

Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.


SA node cell to atrial cardiac muscle cell signaling

Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.


regulation of cell proliferation involved in mesonephros development

Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.


regulation of response to cytokine stimulus

Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.


cell septum edging catabolic process

The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.


Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H+.


snoRNA transcription by RNA polymerase II

The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.


aspartate family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.


peptidyl-lysine trimethylation

The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.


presynaptic membrane assembly

The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.


ion channel modulating, G protein-coupled receptor signaling pathway

The series of molecular signals generated as a consequence of a G protein-coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel.


negative regulation of cellular response to hypoxia

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia.


neural plate thickening

The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.


acetyl-CoA biosynthetic process

The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.


Pup conjugating enzyme activity

Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.


detoxification of nitrogen compound

Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.


regulation of uredinium development

Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.


sequence-specific mRNA binding

Binding to messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.


equator specification

The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.


Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.


Catalysis of the reaction: galactitol-1-phosphate + NAD+ = D-tagatose 6-phosphate + NADH + H+.


interleukin-21 production

The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


pole plasm mitochondrial rRNA localization

Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.


neuromast development

The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.


positive regulation of peptide antigen transport

Any process that activates or increases the frequency, rate or extent of peptide antigen transport.


ether biosynthetic process

The chemical reactions and pathways resulting in the formation of ether.


detection of electrical stimulus involved in sensory perception of pain

The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.


morphogenesis of larval imaginal disc epithelium

The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.


inflammatory cell apoptotic process

Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.


Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.


positive regulation of distal tip cell migration

Any process that activates or increases the frequency, rate or extent of distal tip cell migration.


negative regulation of cardiac muscle hypertrophy in response to stress

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.


cyclohexane monooxygenase activity

Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O.


response to freezing

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.


mesenchyme migration involved in limb bud formation

The migration of mesenchymal tissue that contributes to the formation of a limb bud.


Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.


positive regulation of urine volume

Any process that increases the amount of urine excreted from the body over a unit of time.


CD86 biosynthetic process

The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.


primitive erythrocyte differentiation

Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.


cell chemotaxis involved in Malpighian tubule morphogenesis

The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.


oral apparatus organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.


atrial ventricular junction remodeling

The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.


5'-hydroxyl dinucleotide hydrolase activity

Catalysis of the hydrolysis of phosphodiester bonds in 5'OH-RNA according to the reaction 5'OH-RNA + H20 = 5'OH-NpN (dinucleotide) + 5'P-RNA.


neurofilament cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.


cytoplasmic translation

The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.


glycogen binding

Binding to glycogen.


Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.


Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP+ = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H+ + NADPH.


regulation of atrial cardiac muscle cell action potential

Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.


positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway

Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.


regulation of maltoheptaose metabolic process

Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process.


sex determination, somatic-gonadal interaction

The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism.


Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.


negative regulation of astrocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.


2-hydroxy-but-3-enyl glucosinolate biosynthetic process

The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.


establishment of bipolar cell polarity

The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.


rhombomere 8 morphogenesis

The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


development of secondary female sexual characteristics

The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.


protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity

Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.


negative regulation of intracellular steroid hormone receptor signaling pathway

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


sequestering of BMP in extracellular matrix

Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.


catabolism by virus of host DNA

The breakdown of host DNA, deoxyribonucleic acid, by a virus.


branching involved in mammary gland cord morphogenesis

The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.


monoatomic cation efflux transmembrane transporter activity

Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.


carvone reductase activity

Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone.


Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.


positive regulation of amine catabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.


Catalysis of the reaction: 17alpha-hydroxyprogesterone + O2 + reduced [NADPH--hemoprotein reductase] = 11-deoxycortisol + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


plastoglobule organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.


p-cresol biosynthetic process

The chemical reactions and pathways resulting in the formation of p-cresol.


neuroblast delamination

The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.


fructoselysine catabolic process

The chemical reactions and pathways resulting in the breakdown of fructoselysine.


siderophore catabolic process

The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.


L-sorbose oxidase activity

Catalysis of the reaction: L-sorbose + O2 = 5-dehydro-D-fructose + H2O2.


regulation of erythrocyte apoptotic process

Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.


pancreatic D cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.


The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


lactate racemase activity

Catalysis of the reaction: (S)-lactate = (R)-lactate.


tRNA acetylation

The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


fatty acid ligase activity

Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.


flavin reductase (NADH) activity

Catalysis of the reaction: a reduced flavin + NAD+ = an oxidized flavin + 2 H+ + NADH.


oligodendrocyte cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.


isopimaradienal hydroxylase activity

Catalysis of the reaction: isopimaradienal + NADPH + O2 <=> isopimaric acid + NADP + H2O.


rhombomere 7 development

The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


lysine carbamoyltransferase activity

Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H+ + phosphate.


prophase

The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.


regulation of skeletal muscle cell differentiation

Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.


programmed cell death involved in cell development

The activation of endogenous cellular processes that result in the death of a cell as part of its development.


plasmacytoid dendritic cell activation

A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.


endodermal cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.


Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-.


carbohydrate kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.


positive regulation of synaptic vesicle recycling

Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.


Catalyzes the reaction: UDP-alpha-D-xylose + [protein with EGF-like domain]-3-O-(beta-D-glucosyl)-L-serine <=> UDP + [protein with EGF-like domain]-3-O-(alpha-D-xylosyl-(1->3)-beta-D-glucosyl)-L-serine.


angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure

The process that increases the diameter of a blood vessel via the renin-angiotensin system.


methylthioribulose 1-phosphate dehydratase activity

Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H2O.


regulation of atrichoblast fate specification

Any process that modulates atrichoblast fate specification.


branched duct epithelial cell fate determination, open tracheal system

Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode.


B cell activation involved in immune response

The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


chemoattraction of dopaminergic neuron axon

The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.


post-embryonic hemopoiesis

The stages of blood cell formation that take place after completion of embryonic development.


integrin biosynthetic process

The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.


regulation of lung goblet cell differentiation

Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.


negative regulation of lipoprotein particle clearance

Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.


positive regulation of hair cycle

Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.


Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.


establishment of protein localization to vacuole

The directed movement of a protein to a specific location in a vacuole.


glucose catabolic process to D-lactate and ethanol

The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.


Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid.


allose transmembrane transporter activity

Enables the transfer of allose from one side of a membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.


vascular endothelial cell response to laminar fluid shear stress

Any response to laminar fluid shear stress in a vascular endothelial cell.


glyoxylate cycle

A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.


positive regulation of potassium ion export across plasma membrane

Any process that activates or increases the frequency, rate or extent of potassium ion export across the plasma membrane.


alpha-cuprenene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (-)-alpha-cuprenene + diphosphoric acid.


[methyl-Co(III) methylamine-specific corrinoid protein]:coenzyme M methyltransferase activity

Catalysis of the reaction: [methyl-Co(III) methylamine-specific corrinoid protein] + coenzyme M = [Co(I) methylamine-specific corrinoid protein] + H+ + methyl-coenzyme M. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.


negative regulation of fat cell proliferation

Any process that stops or decreases the rate or extent of fat cell proliferation.


taste bud morphogenesis

The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.


NAD-dependent protein demyristoylase activity

Catalysis of the reaction: N6-tetradecanoyl-L-lysyl-[protein] + NAD+ + H2O = tetradecanoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


regulation of cellular component size

A process that modulates the size of a cellular component.


allantoicase activity

Catalysis of the reaction: allantoate + H2O = (S)-ureidoglycolate + urea.


pinocarveol dehydrogenase activity

Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-.


high-affinity IgE receptor activity

Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


eugenol biosynthetic process

The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.


cranial nerve morphogenesis

The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.


4,6-pyruvylated galactose residue biosynthetic process

The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.


D-arabinose 1-dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.


cGMP-dependent protein kinase activity

cGMP dependent catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein.


regulation of gluconeogenesis

Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.


root hair initiation

The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.


type III site-specific deoxyribonuclease activity

Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.


regulation of muscle cell apoptotic process

Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.


exochitinase activity

Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.


indole alkaloid metabolic process

The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.


Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.


negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.


central nervous system formation

The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.


prenyl-FMNH2 biosynthetic process

The chemical reactions and pathways resulting in prenyl-FMNH2, an essential cofactor for the decarboxylase enzymes UbiD and Fdc1.


CCACCA tRNA nucleotidyltransferase activity

Catalysis of the reaction: an unstable tRNA + 2 ATP + 4 CTP = a tRNA with a 3' CCACCA end + 6 diphosphate.


regulation of sensory perception

Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.


nucleic acid transmembrane transporter activity

Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.


chondrocyte morphogenesis involved in endochondral bone morphogenesis

The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.


amino-acid betaine metabolic process

The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.


Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H+.


berbamunine synthase activity

Catalysis of the reaction: (S)-N-methylcoclaurine + (R)-N-methylcoclaurine + [reduced NADPH--hemoprotein reductase] + O2 = berbamunine + [oxidized NADPH--hemoprotein reductase] + 2 H2O.


mycothiol-dependent detoxification

The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.


organic acid binding

Binding to an organic acid, any acidic compound containing carbon in covalent linkage.


2-aminobenzoyl-CoA reductase activity

Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA.


ADP-ribosylserine hydrolase activity

Catalysis of the reaction: (ADP-D-ribosyl)-L-seryl-[protein] + H2O = L-seryl-[protein] + ADP-ribose.


stress response to acid chemical

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.


epithelial tube branching involved in lung morphogenesis

The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.


neuromuscular junction development

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.


negative regulation of corticotropin-releasing hormone receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.


dextranase activity

Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran.


Catalysis of the reaction: 8'-apo-beta-carotenol + O2 = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal.


negative regulation of intermediate mesodermal cell fate determination

Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.


inositol-3-phosphate synthase activity

Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.


rhamnogalacturonan I backbone metabolic process

The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.


ribonuclease P4 activity

Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor.


dihydroxy-acid dehydratase activity

Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.


positive regulation of macrophage proliferation

Any process that activates or increases the frequency, rate or extent of macrophage proliferation.


monoatomic cation:bicarbonate symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monoatomic cation(out) + HCO3-(out) = monoatomic cation(in) + HCO3-(in).


leucine biosynthetic process

The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.


glucose catabolic process

The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.


Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.


cellular response to trehalose stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.


17alpha-hydroxyprogesterone binding

Binding to 17alpha-hydroxyprogesterone.


negative regulation of reverse cholesterol transport

Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport.


detection of inactivity

The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.


regulation of type B pancreatic cell proliferation

Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.


CUC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CUC codon.


Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H+ + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2.


carbon dioxide receptor activity

Combining with carbon dioxide to initiate a change in cell activity.


endoderm development

The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.


spindle assembly checkpoint signaling

A signaling process that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.


RNA polyadenylation at postsynapse

A polyadenylation event (the enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule) that takes place at a postsynapse.


globose nucleus development

The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.


negative regulation of T cell anergy

Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.


protoaphin-aglucone dehydratase (cyclizing) activity

Catalysis of the reaction: protoaphin aglucone = H2O + xanthoaphin.


trans-geranyl-CoA isomerase activity

Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA.


response to undecane

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.


ferroxidase activity

Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.


positive regulation of immune response

Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.


farnesol biosynthetic process

The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.


optic vesicle formation

The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.


protein deneddylation

The removal of a ubiquitin-like protein of the NEDD8 type from a protein.


iron ion sequestering activity

Binding to an iron ion to prevent it from interacting with other partners or to inhibit its localization to the area of the cell or complex where it is active.


coenzyme F420-0:L-glutamate ligase activity

Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.


fruit dehiscence

The process leading to the spontaneous opening of the fruit permitting the escape of seeds.


atrial septum intermedium development

The progression of the atrial septum intermedium over time, from its formation to the mature structure.


Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O.


cerebellar granular layer development

The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


regulation of response to alcohol

Any process that modulates the frequency, rate or extent of response to alcohol.


regulation of toll-like receptor 7 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.


regulation of MAPK cascade

Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.


ABC-type D-ribose transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in).


histone H3K18 decrotonylase activity

Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone H3 position 18] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone H3] + nicotinamide.


Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H+.


negative regulation of alpha-beta T cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.


box H/ACA snoRNP complex binding

Binding to a box H/ACA snoRNP complex.


tRNA dihydrouridine synthesis

The process whereby a uridine in a transfer RNA is converted to dihydrouridine.


response to carboplatin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.


positive regulation of cytolysis

Any process that activates or increases the frequency, rate or extent of cytolysis.


fumarate reductase (menaquinone)

Catalysis of the reaction: fumarate + a menaquinol = succinate + a menaquinone.


root radial pattern formation

The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis.


(-)-menthol dehydrogenase activity

Catalysis of the reaction: (-)-menthol + NADP+ = (2S,5R)-menthone + H+ + NADPH.


response to immobilization stress combined with electrical stimulus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.


dGTP diphosphatase activity

Catalysis of the reaction: dGTP + H2O = dGMP + H+ + diphosphate.


Atg8 activating enzyme activity

Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.


tRNA 2'-O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing a 2'-O-nucleotide.


NAD-dependent histone deacetylase activity

Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.


cephalosporin biosynthetic process

The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.


protein-DNA ISRE complex assembly

The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.


regulation of action potential firing threshold

Any process that regulates the potential at which an axon potential is triggered.


trophectodermal cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.


modulation of voltage-gated sodium channel activity in another organism

Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.


regulation of hepatocyte differentiation

Any process that modulates the frequency, rate or extent of hepatocyte differentiation.


cellular response to sugar-phosphate stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.


embryonic meristem development

The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.


euchromatin binding

Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin.


protein-L-isoaspartate (D-aspartate) O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.


[2Fe-2S] cluster assembly

The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.


4-hydroxycoumarin metabolic process

The chemical reactions and pathways involving 4-hydroxycoumarin.


protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine

The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.


homophytochelatin synthase (dimmer forming) activity

Catalysis of the reaction: glutathionate + L-gamma-glutamyl-L-cysteinyl-beta-alaninate <=> gamma-Glu-Cys-gamma-Glu-Cys-beta-Ala + glycine.


cellular component biogenesis

A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.


IRES-dependent translational initiation of circular RNA

The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate circular mRNA translation.


perturbation of host adenylate cyclase-mediated signal transduction

A process in which a symbiont alters or subverts an adenylate cyclase-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


molecular carrier activity

Directly binding to a specific ion or molecule and delivering it either to an acceptor molecule or to a specific location.


cellular response to zinc ion starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.


modulation by symbiont of host programmed cell death

Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity

Catalysis of the reaction: H2O + N(1),N(12)-diacetylspermine + O2 = 3-acetamidopropanal + H2O2 + N(1)-acetylspermidine.


modulation by symbiont of jasmonic acid levels in host

The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


uroporphyrinogen decarboxylase activity

Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.


bud dormancy process

A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.


inflammatory response

The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.


3,3',5-tribromobisphenol A reductive dehalogenase activity

Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.


spinal trigeminal nucleus development

The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.


gluconate 2-dehydrogenase activity

Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+.


5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity

Catalysis of the reaction: a 5'-end (N2,N2,N7-trimethyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + 2 H+ + N7-methyl-GMP. Can also use (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA as a substrate.


response to morphine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.


cellular response to vanadate(3-)

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.


phosphatidylcholine metabolic process

The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.


regulation of exit from mitosis

Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.


rhamnose binding

Binding to the D- or L-enantiomer of rhamnose.


leukotriene A4 metabolic process

The chemical reactions and pathways involving leukotriene A4.


metanephric cap development

The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.


geranyltranstransferase activity

Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.


monounsaturated fatty acid catabolic process

The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.


protein localization to actin cytoskeleton

A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.


pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity

Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.


8-demethylnovobiocic acid C8-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 8-desmethylnovobiocic acid <=> S-adenosyl-L-homocysteine + novobiocic acid + H+.


host cell extracellular matrix binding

Binding to the extracellular matrix of a host cell.


D-series resolvin biosynthetic process

The chemical reactions and pathways resulting in the formation of resolvin family D-series, hydroxy fatty acids derived from docosahexaenoic acid.


Fas signaling pathway

The series of molecular signals initiated by the binding of a ligand to a Fas receptor on the surface of the cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.


cellular response to methylmercury

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.


vesicle targeting

The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.


protein localization to ascospore wall

A process in which a protein is transported to, or maintained in, a location within an ascospore wall.


response to brefeldin A

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.


corrin biosynthetic process

The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.


fatty acid oxidation

The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.


neuromast hair cell development

The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.


D-lactate-2-sulfatase activity

Catalysis of the reaction: (R)-2-O-sulfolactate + H2O = (R)-lactate + H+ + sulfate.


Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.


Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.


relaxation of muscle

A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.


response to mercury ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.


glucocorticoid receptor signaling pathway

The series of molecular signals initiated by glucocorticoid binding to its receptor.


The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.


dipyrrin metabolic process

The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.


carbon-halide lyase activity

Catalysis of the breakage of a bond between carbon and any halogen atom.


dGTP metabolic process

The chemical reactions and pathways involving dGTP, guanosine triphosphate.


cellular response to vitamin A

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.


Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.


transferrin receptor activity

Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.


response to glial cell derived neurotrophic factor

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.


regulation of intestinal D-glucose absorption

Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption.


methionine transmembrane transporter activity

Enables the transfer of methionine from one side of a membrane to the other.


leukotriene biosynthetic process

The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.


erythromycin C 3''-o-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin C <=> S-adenosyl-L-homocysteine + erythromycin A + H+.


Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine = AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.


response to nonylphenol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.


Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.


Catalysis of the reaction: 1-18:3-2-16:1-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


response to spindle checkpoint signaling

A process that occurs in response to signals generated as a result of spindle checkpoint signaling.


positive regulation of L-arginine import across plasma membrane

Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane.


regulation of defense response to bacterium

Any process that modulates the frequency, rate or extent of defense response to bacterium.


positive regulation of intracellular cholesterol transport

Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.


vitamin D2 metabolic process

The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.


cytosolic valyl-tRNA aminoacylation

The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


neurotensin receptor activity, non-G protein-coupled

Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.


Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.


D-mannitol oxidase activity

Catalysis of the reaction: mannitol + O2 = mannose + H2O2.


regulation of mitochondrial membrane permeability involved in apoptotic process

Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.


gibberellin-44 dioxygenase activity

Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2.


tubulin deacetylation

The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.


cerebellar stellate cell differentiation

The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.


innervation

The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.


chlorate transmembrane transporter activity

Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.


oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.


endocytosed synaptic vesicle to endosome fusion

Fusion of an endocytosed synaptic vesicle with an endosome.


maturation of SSU-rRNA

Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.


RNA decapping

Cleavage of the 5'-cap of an RNA.


eukaryotic translation initiation factor 2alpha kinase activity

Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.


positive regulation of asexual reproduction

Any process that activates or increases the frequency, rate or extent of asexual reproduction.


positive regulation of toll-like receptor 21 signaling pathway

Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway.


acylphosphatase activity

Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.


natural killer cell proliferation

The expansion of a natural killer cell population by cell division.


mammary placode formation

The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.


Catalysis of the reaction: 4-coumaryl-CoA + cyanidin 3-O-beta-D-glucoside betaine <=> cyanidin 3-(p-coumaroyl)-glucoside + coenzyme A.


allocryptopine 6-hydroxylase activity

Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O.


MAP kinase kinase activity

Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.


nucleotide-sugar transmembrane transporter activity

Enables the transfer of a nucleotide-sugar from one side of a membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.


cell movement involved in somal translocation

The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface.


parental behavior

A reproductive behavior in which a parent cares for and rears offspring.


protein insertion into plasma membrane

The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.


negative regulation of brassinosteroid mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.


tropane alkaloid biosynthetic process

The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.


diterpene phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.


response to antipsychotic drug

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.


envenomation resulting in modulation of voltage-gated potassium channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism.


inositol hexakisphosphate 6-kinase activity

Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.


Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.


cAMP catabolic process

The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).


cyanidin 3-O-glucoside metabolic process

The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside.


MTREC complex binding

Binding to a MTREC complex.


acquisition of plant reproductive competence

The process in which a plant acquires the ability to respond to a floral inductive signal.


response to glycoside

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.


sodium-transporting ATPase activity, rotational mechanism

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out), by a rotational mechanism.


protein depolymerization

The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.


Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.


establishment of ER localization

The directed movement of the endoplasmic reticulum to a specific location.


stomach neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.


siRNA 3'-end processing

The process of forming the mature 3' end of a siRNA molecule.


DNA-mediated transformation

The direct uptake and incorporation of exogenous genetic material (DNA or RNA) into a cell from its surroundings through the cell envelope.


NK T cell differentiation

The process in which a precursor cell type acquires the specialized features of a NK T cell.


sporocarp development

The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.


Catalysis of the reaction: 1-18:3-2-16:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:3-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


The series of molecular signals initiated by interleukin-33 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


viral mRNA cap methylation

An innate immune response evasion mechanism in which a virus methylates the 2'-O-ribose of the first or second transcribed nucleotide of its mRNAs. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs.


regulation of response to ethanol

Any process that modulates the frequency, rate or extent of response to ethanol.


1-alkenyl-2-acylglycerol choline phosphotransferase activity

Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.


urocanate hydratase activity

Catalysis of the reaction: 4-imidazolone-5-propanoate + H+ = trans-urocanate + H2O.


oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.


female pigmentation

Establishment of a pattern of pigment in females.


UDP-xylose transmembrane transporter activity

Enables the transfer of UDP-xylose from one side of a membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.


vesicle fusion with Golgi medial cisterna membrane

The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles.


chondrocyte differentiation

The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.


triose-phosphate transmembrane transporter activity

Enables the transfer of a triose phosphate from one side of a membrane to the other.


fatty acid in-chain hydroxylase activity

Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.


negative regulation of cell-cell adhesion mediated by integrin

Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.


positive regulation of intracellular steroid hormone receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.


neuron projection regeneration

The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.


positive regulation of anti-Mullerian hormone signaling pathway

Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway.


SUMO activating enzyme activity

Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.


response to type III interferon

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.


positive regulation of gastric emptying

Any process that increases the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


ecgonone methyl ester biosynthetic process

The chemical reactions and pathways resulting in the formation of ecgonone methyl ester.


brassinosteroid binding

Binding to a brassinosteroid.


tachykinin receptor activity

Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.


2'-hydroxydaidzein reductase activity

Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.


triokinase activity

Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H+.


Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.


regulation of receptor localization to synapse

Any process that modulates the frequency, rate or extent of receptor localization to synapse.


dimethylallyltranstransferase activity

Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.


positive regulation of exit from mitosis

Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).


response to diuretic

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.


retinal isomerization

The reactions involved in isomerization of all trans to all cis retnal.


indole alkaloid biosynthetic process

The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.


thermospermine oxidase activity

Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.


peptidoglycan stem peptide endopeptidase activity

A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan.


trochlear nerve morphogenesis

The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.


glyceraldehyde oxidoreductase activity

Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H+.


transcription by RNA polymerase III

The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.


fumonisin metabolic process

The chemical reactions and pathways involving fumonisin.


UV protection

Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.


microtubule nucleator activity

The action of a molecule that provides a shape mimicking the end of a microtubule to seed the formation of a new microtubule via self-assembly.


regulation of deacetylase activity

Any process that modulates the frequency, rate or extent of deacetylase activity.


negative regulation of mesenchymal stem cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation.


regulation of circadian sleep/wake cycle, wakefulness

Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.


negative regulation of glial cell proliferation

Any process that stops or decreases the rate or extent of glial cell proliferation.


Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide.


Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+.


hydrolase activity, acting on acid sulfur-nitrogen bonds

Catalysis of the hydrolysis of any acid sulfur-nitrogen bond.


positive regulation of smooth muscle tissue development

Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development.


multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


positive regulation of thymine transport

Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


MutSbeta complex binding

Binding to a MutSbeta mismatch repair complex.


positive regulation of developmental pigmentation

Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.


spongiotrophoblast cell proliferation

The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.


Catalysis of the reaction: 3'-phosphoadenylylselenate + NADPH => adenosine 3',5'-bisphosphate + selenite + NADP+ + H+.


L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine

The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine.


platelet activating factor receptor activity

Combining with platelet activating factor to initiate a change in cell activity.


macrocin O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H+ + tylosin.


regulation of osteoclast differentiation

Any process that modulates the frequency, rate or extent of osteoclast differentiation.


positive regulation of fibroblast chemotaxis

Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis.


regulation of autophagy of mitochondrion in response to mitochondrial depolarization

Any process that modulates the frequency, rate or extent of autophagy of mitochondrion in response to mitochondrial depolarization.


regulation of photoreceptor cell differentiation

Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.


post-embryonic limb morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.


ribonucleotide excision repair

The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.


cellular response to ceramide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.


digestion

The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


regulation of timing of catagen

Any process that modulates the frequency, rate or extent of timing of catagen, the regression phase of the hair cycle.


positive regulation of substrate-dependent cell migration, cell attachment to substrate

Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.


leukotriene B4 metabolic process

The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.


positive regulation of response to water deprivation

Any process that activates or increases the frequency, rate or extent of response to water deprivation.


2-aminoethylphosphonate binding

Binding to 2-aminoethylphosphonate.


farnesylcysteine lyase activity

Catalysis of the reaction: S-[(2E,6E)-farnesyl]-L-cysteine + O2 + H2O <=> (2-trans,6-trans)-farnesal + L-cysteine + hydrogen peroxide.


strand invasion

The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


glycerol-3-phosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.


regulation of inner ear auditory receptor cell fate specification

Any process that mediates the specification of a cell into an auditory hair cell.


Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.


fatty acid alpha-oxygenase activity

Catalysis of the reaction: O2 + a 2,3,4-saturated fatty acid <=> a 2(R)-hydroperoxy fatty acid.


6-sulfoquinovose(1-) metabolic process

The chemical reactions and pathways involving 6-sulfoquinovose(1-).


positive regulation of astrocyte differentiation

Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.


serotonergic neuron axon guidance

The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.


detection of chemical stimulus

The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.


organophosphate catabolic process

The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.


pattern specification involved in pronephros development

Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.


regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway

Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.


central nervous system segmentation

Division of the central nervous system into a series of semi-repetitive parts or segments.


cycloeucalenol cycloisomerase activity

Catalysis of the reaction: cycloeucalenol = obtusifoliol.


Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.


negative regulation of platelet aggregation

Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


cytoplasmic translational initiation

The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.


rRNA pseudouridine synthesis

The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.


skin development

The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.


ribonucleoprotein complex localization

Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.


positive regulation of epithelial cell differentiation involved in kidney development

Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.


dCTP diphosphatase activity

Catalysis of the reaction: dCTP + H2O = dCMP + H+ + diphosphate.


sabinene synthase activity

Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate.


regulation of phosphorelay signal transduction system

Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.


eukaryotic translation initiation factor 2 complex assembly

The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex.


regulation of radial pattern formation

Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.


pyloric sphincter smooth muscle contraction

A process in which force is generated within gastric smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the narrowest part of the pylorus that separates the stomach from the duodenum.


osmolarity-sensing monoatomic cation channel activity

Enables the transmembrane transfer of a monoatomic cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.


negative regulation of cardiac muscle cell apoptotic process

Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.


male germ-line stem cell population maintenance

The process by which an organism or tissue maintains a population of male germ-line stem cells.


negative regulation of inflammatory response to wounding

Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding.


auxin transmembrane transporter activity

Enables the transfer of auxins from one side of a membrane to the other. Auxins are plant hormones that regulate aspects of plant growth.


mesonephric duct morphogenesis

The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.


corneal epithelial cell migration

The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism.


berberine reductase activity

Catalysis of the reaction: (R)-canadine + 2 NADP+ = berberine + H+ + 2 NADPH.


positive regulation of olefin biosynthetic process

Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process.


Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.


transforming growth factor beta receptor activity, type I

Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.


alpha-keto ester reductase activity

Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic.


positive regulation of fibroblast growth factor receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.


chlorophyll catabolite transmembrane transporter activity

Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of a membrane to the other.


tooth replacement

The process whose specific outcome is the replacement of an existing tooth with another tooth.


trimming of terminal mannose on B branch

The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.


acceptance of pollen

The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes.


NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity

Catalysis of the reaction: [protein]-C-terminal glycine + NAD+ = [protein]-C-terminal O-(ADP-D-ribosyl)-glycine + nicotinamide.


DNA-binding transcription activator activity, RNA polymerase II-specific

A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.


negative regulation of arbuscule formation for nutrient acquisition from host

Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


tRNA-intron endonuclease activity

Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.


ATP-dependent histone chaperone activity

Binding to and carrying a histone or a histone complex to unload or deposit it as a nucleosome, driven by ATP hydrolysis.


cell-substrate junction disassembly

The disaggregation of a cell-substrate junction into its constituent components.


enteric smooth muscle cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.


positive regulation of response to oxidative stress

Any process that activates or increases the frequency, rate or extent of response to oxidative stress.


calcium-dependent ATPase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+).


GDP-mannose 3,5-epimerase activity

Catalysis of the reaction: GDP-mannose = GDP-L-galactose.


propylene catabolic process

The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining.


mammary gland epithelial cell differentiation

The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.


synaptic vesicle uncoating

The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane.


ethanolaminephosphotransferase activity

Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.


walking behavior

The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.


Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-.


phenyl propionate uniporter activity

Enables the transfer of phenyl propionate from one side of a membrane to the other.


dendritic cell proliferation

The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.


leukocyte activation involved in immune response

A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.


negative regulation of dense core granule biogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis.


alpha,alpha-trehalose phosphorylase (configuration-retaining) activity

Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.


regulation of dehydroepiandrosterone secretion

Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion.


regulation of cytokinetic process

Any process that modulates the frequency, rate or extent of a cytokinetic process.


gene conversion of immunoglobulin genes involved in immune response

The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response.


Catalysis of the reaction: 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-[N-acetyl-beta-D-glucosaminyl-(1->3)-N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H+ + UDP.


protein O-glucuronidation

The modification of a protein by glucuronidation on an amino acid oxygen atom.


detection of chemical stimulus involved in sensory perception of sweet taste

The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.


kidney epithelium development

The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.


The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.


cellular response to mannitol stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.


vestibulocochlear nerve maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.


azobenzene reductase activity

Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+.


granulocyte migration

The movement of a granulocyte within or between different tissues and organs of the body.


cerebral cortex development

The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.