Ajmalicine

A monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure.


Promazine

A phenothiazine deriative in which the phenothiazine tricycle has a 3-(dimethylaminopropyl) group at the N-10 position.


A member of the class of benzaldehydes carrying a diethylamino substituent at position 4.


Brompheniramine

Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.


Rifamycin

A member of the class of rifamycins that exhibits antibiotic and antitubercular properties.


A secondary alcohol that is butane substituted by a hydroxy group at position 2.


Parnate

A 2-phenylcyclopropan-1-amine that is the (1R,2S)-enantiomer of tranylcypromine.


Nisoldipine

A racemate consisting of equimolar amounts of (R)- and (S)-nisoldipine. A calcium channel blocker, it is used in the treatment of hypertension and angina pectoris.


Chlorhexidine

A bisbiguanide compound with a structure consisting of two (p-chlorophenyl)guanide units linked by a hexamethylene bridge.


tert-Butanol

A tertiary alcohol alcohol that is isobutane substituted by a hydroxy group at position 2.


An organic phosphonate that is the trisacetoxymethylester derivative of naphthalene substituted  hydroxymethylphosphonic acid. It has been found to inhibit insulin receptor tyrosine kinase activity and insulin stimulated glucose oxidation.


A member of the class of isoquinolines that is the sulfonamide formed by the formal condensation of the sulfo group of 4-methylisoquinoline-5-sulfonic acid with the 1-amino group of (S)-2-methyl-1,4-diazepane.


N-Oleoyldopamine

A fatty amide resulting from the formal condensation of the carboxy group of oleic acid with the amino group of dopamine. Synthesised in catecholaminergic neurons, it crosses the blood-brain barrier and might be considered as a carrier of dopamine into the brain. It is a  transient receptor potential vanilloid type 1 (TRPV1) receptor agonist.


enzyme inhibitor

A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.


An alkyl alcohol that is pentane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It has been isolated from Melicope ptelefolia.


Bretylium tosylate

The tosylate salt of bretylium.  It blocks noradrenaline release from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation.


Cyclobenzaprine

5-Methylidene-5H-dibenzo[a,d]cycloheptene in which one of the hydrogens of the methylidene group is substituted by a 2-(dimethylamino)ethyl group. A centrally acting skeletal muscle relaxant, it is used as its hydrochloride salt in the symptomatic treatment of painful muscle spasm.


Diphenidol

A tertiary alcohol that is butan-1-ol substituted by two phenyl groups at position 1 and a piperidin-1-yl group at position 4.


Cefazolin

A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively.


Edelfosine

A glycerophosphocholine that is glycero-3-phosphocholine substituted at positions 1 and 2 by octadecyl and methyl groups respectively.


Clorprenaline

A racemate comprise of equimolar amounts of (R)- and (S)-clorprenaline. It is a beta2-adrenergic receptor agonist and a bronchodilator.


Terconazole

A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have R and S configuration, respectively.


Azosemide

A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hypertension.


Quinaprilat

A dicarboxylic acid resulting from the hydrolysis of the ethyl ester group of quinapril to give the corresponding dicarboxylic acid. The active angiotensin-converting enzyme inhibitor (ACE inhibitor) of the prodrug quinapril.


Acetophenone

A methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.


Dexbrompheniramine

The (pharmacologically active) (S)-(+)-enantiomer of brompheniramine. A histamine H1 receptor antagonist, it is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.


Mosapride

A benzamide resulting from the formal condensation of the carboxy group of 4-amino-5-chloro-2-ethoxybenzoic acid with the amino group of 1-[4-(4-fluorobenzyl)morpholin-2-yl]methanamine.


An alpha-bromoketone that is acetophenone substituted by a bromo group at position 2.


A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities.


Bithionol

An aryl sulfide that is diphenyl sulfide in which each phenyl group is substituted at position 2 by hydroxy and at positions 3 and 5 by chlorine. A fungicide and anthelmintic, it was used in various topical drug products for the treatment of liver flukes, but withdrawn after being shown to be a potent photosensitizer with the potential to cause serious skin disorders.


Iodoquinol

A monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 are replaced by iodine.  It is considered the drug of choice for treating asymptomatic or moderate forms of amoebiasis.


Octanoylcarnitine

An O-acylcarnitine having octanoyl as the acyl substituent.


ATOVAQUONE

A naphthoquinone compound having a 4-(4-chlorophenyl)cyclohexyl group at the 2-position and a hydroxy substituent at the 3-position.


Chlorprothixene

A chlorprothixene in which the double bond adopts a (Z)-configuration.


Lornoxicam

A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations.


(1-((2-Methoxy-4-(((phenylsulfonyl)amino)carbonyl)phenyl)methyl)-1H-indazol-6-yl)carbamic acid cyclopentyl ester


The class of beta-lactam antibiotics that whose members have a carbapenem skeleton which is variously substituted at positions 3, 4, and 6.


Diethyl pyrocarbonate

The diethyl ester of dicarbonic acid.


Dyclonine

N-Ethylpiperidine in which one of the hydrogens attached to the methyl group is substituted by a 4-butoxybenzoyl group.


A phytocannabinoid that is Delta(9)-tetrahydrocannabinol in which the C-11 methyl has been fully oxidised to a carboxy group. Further enzymatic oxidation product of 11-hydroxy-Delta(9)-tetrahydrocannabinol.


Flumazenil

An organic heterotricyclic compound that is 5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine which is substituted at positions 3, 5, 6, and 8 by ethoxycarbonyl, methyl, oxo, and fluoro groups, respectively. It is used as an antidote to benzodiazepine overdose.


Glutaric acid

An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.


Betamethasone dipropionate

A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.


Guanidine carrying a phenyl substituent on each of the two amino groups. It is used as an accelerator in the rubber industry.


Eperisone

A racemate that is an equimolar mixture of (R)- and (S)-eperisone. It is used (as the hydrochloride salt) as a muscle relaxant for the symptomatic treatment of muscle spasm and spasticity.


Serpentine (alkaloid)

An indole alkaloid that is 18-oxayohimban dehydrogenated at positions 3, 4, 5, 6, 16 and 17 and substituted by a methyl group at the 19alpha position and by a methoxycarbonyl group at position 16.


HYOSCYAMINE

An atropine with a 2S-configuration.


The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.


Sodium Bromide

An inorganic sodium salt having bromide as the counterion.


Antazoline

A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.


Cardenolide

A steroid lactone that is a C23 steroid with methyl groups at C-10 and C-13 and a butenolide ring at C-17.


Dicyclomine

The ester resulting from the formal condensation of 1-cyclohexylcyclohexanecarboxylic acid with 2-(diethylamino)ethanol. An anticholinergic, it is used as the hydrochloride to treat or prevent spasm in the muscles of the gastrointestinal tract, particularly that associated with irritable bowel syndrome.


flavin

A derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.


Amperozide

A member of the class of ureas that is urea in which three of the four hydrogens are replaced by ethyl and 4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl groups. An atypical antipsychotic which was in clinical development for the treatment of schizophrenia and substance-related disorders. It is a potent 5-HT2A antagonist and used in veterinary medicine because of its sedative effect on pigs.


cyclic ADP-ribose

A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.


Lysergol

An alkaloid of the ergoline family that occurs as a minor constituent in some species of fungi and in the morning glory family of plants. Its structure is that of ergoline with a methyl group at N-6 and a beta-hydroxymethyl substituent at C-8.


Adipic Acid

An alpha,omega-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.


Monepantel

A secondary carboxamide resulting from the formal condensation of the carboxy group of p-[(trifluoromethyl)sulfanyl]benzoic acid with the amino group of (2S)-2-amino-3-hydroxy-2-methylpropanenitrile in which the hydroxy group has been converted to the corresponding 5-cyano-2-(trifluoromethyl)phenyl ether. A broad-spectrum nematicide, it is used to control gastrointestinal roundworms in sheep and goats.


Phenothiazine

The 10H-tautomer of phenothiazine.


Pridinol

A piperidine substituted at position 1 by a 3-hydroxy-3,3-diphenylpropyl group.


Cefonicid

A cephalosporin bearing {[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and (R)-2-hydroxy-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton.


Adrenosterone

A 3-oxo Delta(4)-steroid that is androst-4-ene carrying three oxo-substituents at positions 3, 11 and 17.


Carbinoxamine

An organochlorine compound that is 2-(4-chlorobenzyl)pyridine in which one of the benzylic hydrogens is substituted by 2-(dimethylamino)ethoxy group. It is an ethanolamine-type antihistamine, used as its maleate salt for treating hay fever, as well as mild cases of Parkinson's disease.


Trimipramine

A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)-2-methylpropyl group at the nitrogen atom. It is used as an antidepressant.


(+)-Himbacine

A  piperidine alkaloid that is decahydronaphtho[2,3-c]furan-1(3H)-one substituted by a methyl group at position 3 and a 2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl group at position 4. It has been isolated from the bark of Australian magnolias.


Perfluorodecalin

A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.


Eliprodil

A member of the class of piperidines that is piperidine substituted by a 2-(4-chlorophenyl)-2-hydroxyethyl group at position 1 and by a 4-fluorobenzyl group at position 4.


Bapta

A polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene.


Phosphomethylphosphonic acid adenylate ester


A salicylanilide derivative with chloride substituents at C-3 and C-5 of the salicylate moiety and at C-3 and C-4 of the anilide moiety.


A  glycosyloxyflavone that is  luteolin substituted by a beta-D-glucopyranosyl residue at position 4' via a glycosidic linkage. It has been isolated from Olea europaea.


Sodium chromate

An inorganic sodium salt consisting of sodium and chromate ions in a 2:1 ratio.


male reproductive organ

biolink:GrossAnatomicalStructure biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A male organ involved in reproduction.


Rulide

A major geometrical isomer of roxithromycin.


aromatase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.


aromatase

A protein that is a translation product of the human CYP19A1 gene or a 1:1 ortholog thereof.


Phthalimide substituted at the 4- and 5-positions by anilino groups.


Alclofenac

An aromatic ether in which the ether oxygen links an allyl group to the 4-position of (3-chlorophenyl)acetic acid.A non-steroidal anti-inflammatory drug, it was withdrawn from the UK market in 1979 due to concerns with its association with vasculitis and rash.


Meclofenamic acid

An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis.


Tiaprofenic acid

An aromatic ketone that is thiophene substituted at C-2 by benzoyl and at C-4 by a 1-carboxyethyl group.


Nicotinic acid riboside

Conjugate base of D-ribosylnicotinic acid.


Leucovorin

A formyltetrahydrofolic acid in which the formyl group is located at position 5.


PUM1_HUMAN Pumilio homolog 1 (sprot)

A pumilio homolog 1 that is encoded in the genome of human.


DTBP1_HUMAN Dysbindin (sprot)

A dysbindin that is encoded in the genome of human.


BL1S4_HUMAN Biogenesis of lysosome-related organelles complex 1 subunit 4 (sprot)

A biogenesis of lysosome-related organelles complex 1 subunit 4 that is encoded in the genome of human.


SH319_HUMAN SH3 domain-containing protein 19 (sprot)

An SH3 domain-containing protein 19 that is encoded in the genome of human.


EPN4_HUMAN Clathrin interactor 1 (sprot)

A clathrin interactor 1 that is encoded in the genome of human.


A deoxyribonuclease-2-alpha that is encoded in the genome of human.


AP3B1_HUMAN AP-3 complex subunit beta-1 (sprot)

An AP-3 complex subunit beta-1 that is encoded in the genome of human.


SNX2_HUMAN Sorting nexin-2 (sprot)

A sorting nexin-2 that is encoded in the genome of human.


HIP1R_HUMAN Huntingtin-interacting protein 1-related protein (sprot)

A huntingtin-interacting protein 1-related protein that is encoded in the genome of human.


CBPD_HUMAN Carboxypeptidase D (sprot)

A carboxypeptidase D that is encoded in the genome of human.


SNAPN_HUMAN SNARE-associated protein Snapin (sprot)

A SNARE-associated protein Snapin that is encoded in the genome of human.


MPRD_HUMAN Cation-dependent mannose-6-phosphate receptor (sprot)

A cation-dependent mannose-6-phosphate receptor that is encoded in the genome of human.


TPD52_HUMAN Tumor protein D52 (sprot)

A tumor protein D52 that is encoded in the genome of human.


TBC8B_HUMAN TBC1 domain family member 8B (sprot)

A TBC1 domain family member 8B that is encoded in the genome of human.


PICAL_HUMAN Phosphatidylinositol-binding clathrin assembly protein (sprot)

A phosphatidylinositol-binding clathrin assembly protein that is encoded in the genome of human.


TPD53_HUMAN Tumor protein D53 (sprot)

A tumor protein D53 that is encoded in the genome of human.


AP3S1_HUMAN AP-3 complex subunit sigma-1 (sprot)

An AP-3 complex subunit sigma-1 that is encoded in the genome of human.


YIPF6_HUMAN Protein YIPF6 (sprot)

A protein YIPF6 that is encoded in the genome of human.


SORT_HUMAN Sortilin (sprot)

A sortilin that is encoded in the genome of human.


AP4E1_HUMAN AP-4 complex subunit epsilon-1 (sprot)

An AP-4 complex subunit epsilon-1 that is encoded in the genome of human.


SNX5_HUMAN Sorting nexin-5 (sprot)

A sorting nexin-5 that is encoded in the genome of human.


AP4B1_HUMAN AP-4 complex subunit beta-1 (sprot)

An AP-4 complex subunit beta-1 that is encoded in the genome of human.


M1IP1_HUMAN Mid1-interacting protein 1 (sprot)

A Mid1-interacting protein 1 that is encoded in the genome of human.


THRSP_HUMAN Thyroid hormone-inducible hepatic protein (sprot)

A thyroid hormone-inducible hepatic protein that is encoded in the genome of human.


CER1_HUMAN Cerberus (sprot)

A cerberus that is encoded in the genome of human.


FSTL1_HUMAN Follistatin-related protein 1 (sprot)

A follistatin-related protein 1 that is encoded in the genome of human.


CRDL1_HUMAN Chordin-like protein 1 (sprot)

A chordin-like protein 1 that is encoded in the genome of human.


GREM2_HUMAN Gremlin-2 (sprot)

A gremlin-2 that is encoded in the genome of human.


DCNL3_HUMAN DCN1-like protein 3 (sprot)

A DCN1-like protein 3 that is encoded in the genome of human.


DCNL2_HUMAN DCN1-like protein 2 (sprot)

A DCN1-like protein 2 that is encoded in the genome of human.


DCNL4_HUMAN DCN1-like protein 4 (sprot)

A DCN1-like protein 4 that is encoded in the genome of human.


DCNL1_HUMAN DCN1-like protein 1 (sprot)

A DCN1-like protein 1 that is encoded in the genome of human.


DCNL5_HUMAN DCN1-like protein 5 (sprot)

A DCN1-like protein 5 that is encoded in the genome of human.


BLNK_HUMAN B-cell linker protein (sprot)

A B-cell linker protein that is encoded in the genome of human.


NOSIP_HUMAN Nitric oxide synthase-interacting protein (sprot)

A nitric oxide synthase-interacting protein that is encoded in the genome of human.


TRIFLUMIZOLE

A carboxamidine resulting from the formal condensation of the amino group of 4-chloro-2-(trifluoromethyl)aniline with the oxygen of the acetyl group of N-(propoxyacetyl)imidazole. A sterol demethylation inhibitor, it is used as a fungicide for the control of powdery mildew, scab and other diseases on a variety of crops.


o-Phthalaldehyde

A dialdehyde in which two formyl groups are attached to adjacent carbon centres on a benzene ring.


Octyl gallate

A gallate ester obtained by condensation of the carboxy group of gallic acid with the hydroxy group of octanol.


A member of the class of phenols carrying two tert-butyl substituents at positions 2 and 4.


A member of the class of phenols carrying two tert-butyl substituents at positions 2 and 6.


Methyl linoleate

A  fatty acid methyl ester of  linoleic acid. It has been isolated from Neolitsea daibuensis.


Methyltrioctylammonium chloride

An organic chloride salt having methyltrioctylammonium as the cation.


Kathon 930

A 1,2-thiazole that is 1,2-thiazol-3(2H)-one substituted by chloro groups at positions 4 and 5 and an octyl group at position 2. It is used as a fungicide.


Fast Green FCF

An organic sodium salt having 2-{(4-{ethyl[(3-sulfonatophenyl)methyl]amino}phenyl)[4-{ethyl[(3-sulfonatophenyl)methyl]iminio}cyclohexa-2,5-dien-1-ylidene]methyl}-5-hydroxybenzene-1-sulfonate as the counterion. Used as a substitute for Light green SF yellowish in Masson's trichrome as it is less likely to fade, and is more brilliant in colour. Also used as a food colouring agent.


Cetrimonium

A quaternary ammonium ion in which the substituents on nitrogen are one hexadecyl and three methyl groups.


Sotradecol

An organic sodium salt having tetradecyl sulfate as the counterion. Used in the treatment of small uncomplicated varicose veins of the lower extremities that show simple dilation with competent valves.


Direct red 81

An organic sodium salt resulting from the formal condensation of Sirius red 4B (acid form) with two equivalents of sodium hydroxide. Used as the plasma stain in some trichrome staining methods.


Eosin

An organic sodium salt that is 2',4',5',7'-tetrabromofluorescein in which the carboxy group and the phenolic hydroxy group have been deprotonated and the resulting charge is neutralised by two sodium ions.


Dodecyltrimethylammonium

A quarternary ammonium cation having one dodecyl and three methyl substituents around the central nitrogen.


Tribromsalan

A salicylanilide derivative with bromo- substituents at C-3 and C-5 of the salicylate moiety and at C-4 of the anilide moiety.


A nitrotyrosine comprising tyrosine having a nitro group at the 3-position on the phenyl ring.


Bromophenol Blue

3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye.


Perchlorate

A monovalent inorganic anion obtained by deprotonation of perchloric acid.


1,3-Benzothiazole substituted at the 2-position with a sulfanyl group.


Mancozeb

A mixture composed from maneb and zineb, which is used as a broad-spectrum contact fungicide.


Zineb

A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU.


regulatory ncRNA-mediated gene silencing

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation.


GRB14_HUMAN Growth factor receptor-bound protein 14 (sprot)

A growth factor receptor-bound protein 14 that is encoded in the genome of human.


2-Bromohexadecanoic acid

A bromo fatty acid that is hexadecanoic (palmitic) acid carrying a single bromo substituent at position 2.


Talarozole

A member of the class of benzothiazoles that is 2-amino-1,3-benzothiazole in which one of the amino hydrogens is replaced by a 4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl group.


Betulin

A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-hydroxymethyl substituents.


brefeldin A

A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity.


Cycloserine

A 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and  D-alanine--D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis).


Methenamine

A polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms.


Psorospermin

An organic heterotetracyclic compound that is 1,2-dihydro-6H-furo[2,3-c]xanthene substituted by a hydroxy group at position 10, a methoxy group at position 5 nad a 2-methyloxiran-2-yl group at position 2.


Brequinar

A quinolinemonocarboxylic acid that is quinoline substituted by 2'-fluoro[1,1'-biphenyl]-4-yl, methyl, carboxy and fluoro groups at positions 2, 3, 4, and 6, respectively. It is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. The compound exhibits antineoplastic and antiviral properties.


Isobavachalcone

A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4' and a prenyl group at position 3'.


Cyclohexene

A cycloalkene that is cylohexane with a single double bond.


An alkanethiol that is propane substituted by a thiol group at position 1.


An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.


A tripeptide consisting of Z-Val-Ala-Asp(OMe) in which the C-terminal OH group has been replaced by a fluoromethyl group. An irreversible pan-caspase inhibitor.


MED6_HUMAN Mediator of RNA polymerase II transcription subunit 6 (sprot)

A mediator of RNA polymerase II transcription subunit 6 that is encoded in the genome of human.


MED7_HUMAN Mediator of RNA polymerase II transcription subunit 7 (sprot)

A mediator of RNA polymerase II transcription subunit 7 that is encoded in the genome of human.


MED4_HUMAN Mediator of RNA polymerase II transcription subunit 4 (sprot)

A mediator of RNA polymerase II transcription subunit 4 that is encoded in the genome of human.


MED13_HUMAN Mediator of RNA polymerase II transcription subunit 13 (sprot)

A mediator of RNA polymerase II transcription subunit 13 that is encoded in the genome of human.


MED17_HUMAN Mediator of RNA polymerase II transcription subunit 17 (sprot)

A mediator of RNA polymerase II transcription subunit 17 that is encoded in the genome of human.


CCNC_HUMAN Cyclin-C (sprot)

A cyclin-C that is encoded in the genome of human.


MED23_HUMAN Mediator of RNA polymerase II transcription subunit 23 (sprot)

A mediator of RNA polymerase II transcription subunit 23 that is encoded in the genome of human.


MED16_HUMAN Mediator of RNA polymerase II transcription subunit 16 (sprot)

A mediator of RNA polymerase II transcription subunit 16 that is encoded in the genome of human.


MED14_HUMAN Mediator of RNA polymerase II transcription subunit 14 (sprot)

A mediator of RNA polymerase II transcription subunit 14 that is encoded in the genome of human.


MED10_HUMAN Mediator of RNA polymerase II transcription subunit 10 (sprot)

A mediator of RNA polymerase II transcription subunit 10 that is encoded in the genome of human.


MED24_HUMAN Mediator of RNA polymerase II transcription subunit 24 (sprot)

A mediator of RNA polymerase II transcription subunit 24 that is encoded in the genome of human.


MED26_HUMAN Mediator of RNA polymerase II transcription subunit 26 (sprot)

A mediator of RNA polymerase II transcription subunit 26 that is encoded in the genome of human.


MED8_HUMAN Mediator of RNA polymerase II transcription subunit 8 (sprot)

A mediator of RNA polymerase II transcription subunit 8 that is encoded in the genome of human.


MED12_HUMAN Mediator of RNA polymerase II transcription subunit 12 (sprot)

A mediator of RNA polymerase II transcription subunit 12 that is encoded in the genome of human.


MED15_HUMAN Mediator of RNA polymerase II transcription subunit 15 (sprot)

A mediator of RNA polymerase II transcription subunit 15 that is encoded in the genome of human.


MED30_HUMAN Mediator of RNA polymerase II transcription subunit 30 (sprot)

A mediator of RNA polymerase II transcription subunit 30 that is encoded in the genome of human.


MED27_HUMAN Mediator of RNA polymerase II transcription subunit 27 (sprot)

A mediator of RNA polymerase II transcription subunit 27 that is encoded in the genome of human.


MED25_HUMAN Mediator of RNA polymerase II transcription subunit 25 (sprot)

A mediator of RNA polymerase II transcription subunit 25 that is encoded in the genome of human.


MED20_HUMAN Mediator of RNA polymerase II transcription subunit 20 (sprot)

A mediator of RNA polymerase II transcription subunit 20 that is encoded in the genome of human.


MED31_HUMAN Mediator of RNA polymerase II transcription subunit 31 (sprot)

A mediator of RNA polymerase II transcription subunit 31 that is encoded in the genome of human.


ZN320_HUMAN Zinc finger protein 320 (sprot)

A zinc finger protein 320 that is encoded in the genome of human.


Z804B_HUMAN Zinc finger protein 804B (sprot)

A zinc finger protein 804B that is encoded in the genome of human.


KRBA1_HUMAN Protein KRBA1 (sprot)

A protein KRBA1 that is encoded in the genome of human.


ZN840_HUMAN Putative zinc finger protein 840 (sprot)


ZN860_HUMAN Zinc finger protein 860 (sprot)

A zinc finger protein 860 that is encoded in the genome of human.


ZN233_HUMAN Zinc finger protein 233 (sprot)

A zinc finger protein 233 that is encoded in the genome of human.


ZN729_HUMAN Zinc finger protein 729 (sprot)

A zinc finger protein 729 that is encoded in the genome of human.


ZN726_HUMAN Zinc finger protein 726 (sprot)

A zinc finger protein 726 that is encoded in the genome of human.


ZN716_HUMAN Zinc finger protein 716 (sprot)

A zinc finger protein 716 that is encoded in the genome of human.


ZN839_HUMAN Zinc finger protein 839 (sprot)

A zinc finger protein 839 that is encoded in the genome of human.


ZN785_HUMAN Zinc finger protein 785 (sprot)

A zinc finger protein 785 that is encoded in the genome of human.


ZN724_HUMAN Zinc finger protein 724 (sprot)

A protein that is a translation product of the ZNF724 gene in human.


ZN727_HUMAN Putative zinc finger protein 727 (sprot)

A protein that is a translation product of the ZNF727 gene in human.


Z705G_HUMAN Putative zinc finger protein 705G (sprot)

A putative zinc finger protein 705G that is encoded in the genome of human.


Z705E_HUMAN Putative zinc finger protein 705EP (sprot)

A putative zinc finger protein 705EP that is encoded in the genome of human.


ZNF99_HUMAN Zinc finger protein 99 (sprot)

A zinc finger protein 99 that is encoded in the genome of human.


ZN736_HUMAN Zinc finger protein 736 (sprot)

A zinc finger protein 736 that is encoded in the genome of human.


ZN732_HUMAN Zinc finger protein 732 (sprot)

A zinc finger protein 732 that is encoded in the genome of human.


ZN195_HUMAN Zinc finger protein 195 (sprot)

A zinc finger protein 195 that is encoded in the genome of human.


ZN197_HUMAN Zinc finger protein 197 (sprot)

A zinc finger protein 197 that is encoded in the genome of human.


ZN213_HUMAN Zinc finger protein 213 (sprot)

A zinc finger protein 213 that is encoded in the genome of human.


ZN263_HUMAN Zinc finger protein 263 (sprot)

A zinc finger protein 263 that is encoded in the genome of human.


ZN264_HUMAN Zinc finger protein 264 (sprot)

A zinc finger protein 264 that is encoded in the genome of human.


ZN208_HUMAN Zinc finger protein 208 (sprot)

A zinc finger protein 208 that is encoded in the genome of human.


ZN749_HUMAN Zinc finger protein 749 (sprot)

A zinc finger protein 749 that is encoded in the genome of human.


ZN500_HUMAN Zinc finger protein 500 (sprot)

A zinc finger protein 500 that is encoded in the genome of human.


Z354A_HUMAN Zinc finger protein 354A (sprot)

A zinc finger protein 354A that is encoded in the genome of human.


ZN253_HUMAN Zinc finger protein 253 (sprot)

A zinc finger protein 253 that is encoded in the genome of human.


ZN737_HUMAN Zinc finger protein 737 (sprot)

A zinc finger protein 737 that is encoded in the genome of human.


ZN254_HUMAN Zinc finger protein 254 (sprot)

A zinc finger protein 254 that is encoded in the genome of human.


Z324A_HUMAN Zinc finger protein 324A (sprot)

A zinc finger protein 324A that is encoded in the genome of human.


ZN189_HUMAN Zinc finger protein 189 (sprot)

A zinc finger protein 189 that is encoded in the genome of human.


ZN432_HUMAN Zinc finger protein 432 (sprot)

A zinc finger protein 432 that is encoded in the genome of human.


ZN202_HUMAN Zinc finger protein 202 (sprot)

A zinc finger protein 202 that is encoded in the genome of human.


RHIT_HUMAN Transcriptional repressor RHIT (sprot)

A zinc finger protein 205 that is encoded in the genome of human.


ZN682_HUMAN Zinc finger protein 682 (sprot)

A zinc finger protein 682 that is encoded in the genome of human.


ZN688_HUMAN Zinc finger protein 688 (sprot)

A zinc finger protein 688 that is encoded in the genome of human.


ZN735_HUMAN Putative zinc finger protein 735 (sprot)

A protein that is a translation product of the ZNF735 gene in human.


Z705D_HUMAN Zinc finger protein 705D (sprot)

A zinc finger protein 705D that is encoded in the genome of human.


ZN875_HUMAN Zinc finger protein 875 (sprot)

A zinc finger protein 875 that is encoded in the genome of human.


ZN250_HUMAN Zinc finger protein 250 (sprot)

A zinc finger protein 250 that is encoded in the genome of human.


ZNF12_HUMAN Zinc finger protein 12 (sprot)

A zinc finger protein 12 that is encoded in the genome of human.


ZNF14_HUMAN Zinc finger protein 14 (sprot)

A zinc finger protein 14 that is encoded in the genome of human.


ZN708_HUMAN Zinc finger protein 708 (sprot)

A zinc finger protein 708 that is encoded in the genome of human.


ZNF17_HUMAN Zinc finger protein 17 (sprot)

A zinc finger protein 17 that is encoded in the genome of human.


ZNF18_HUMAN Zinc finger protein 18 (sprot)

A zinc finger protein 18 that is encoded in the genome of human.


ZNF19_HUMAN Zinc finger protein 19 (sprot)

A zinc finger protein 19 that is encoded in the genome of human.


ZNF20_HUMAN Zinc finger protein 20 (sprot)

A zinc finger protein 20 that is encoded in the genome of human.


ZNF23_HUMAN Zinc finger protein 23 (sprot)

A zinc finger protein 23 that is encoded in the genome of human.


ZKSC1_HUMAN Zinc finger protein with KRAB and SCAN domains 1 (sprot)

A zinc finger protein with KRAB and SCAN domains 1 that is encoded in the genome of human.


ZNF25_HUMAN Zinc finger protein 25 (sprot)

A zinc finger protein 25 that is encoded in the genome of human.


ZNF26_HUMAN Zinc finger protein 26 (sprot)

A zinc finger protein 26 that is encoded in the genome of human.


ZN37A_HUMAN Zinc finger protein 37A (sprot)

A zinc finger protein 37A that is encoded in the genome of human.


ZNF28_HUMAN Zinc finger protein 28 (sprot)

A zinc finger protein 28 that is encoded in the genome of human.


ZNF3_HUMAN Zinc finger protein 3 (sprot)

A zinc finger protein 3 that is encoded in the genome of human.


ZNF43_HUMAN Zinc finger protein 43 (sprot)

A zinc finger protein 43 that is encoded in the genome of human.


ZNF30_HUMAN Zinc finger protein 30 (sprot)

A zinc finger protein 30 that is encoded in the genome of human.


ZNF10_HUMAN Zinc finger protein 10 (sprot)

A zinc finger protein 10 that is encoded in the genome of human.


ZN157_HUMAN Zinc finger protein 157 (sprot)

A zinc finger protein 157 that is encoded in the genome of human.


ZNF41_HUMAN Zinc finger protein 41 (sprot)

A zinc finger protein 41 that is encoded in the genome of human.


ZN75D_HUMAN Zinc finger protein 75D (sprot)

A zinc finger protein 75D that is encoded in the genome of human.


ZN133_HUMAN Zinc finger protein 133 (sprot)

A zinc finger protein 133 that is encoded in the genome of human.


ZN136_HUMAN Zinc finger protein 136 (sprot)

A zinc finger protein 136 that is encoded in the genome of human.


ZN140_HUMAN Zinc finger protein 140 (sprot)

A zinc finger protein 140 that is encoded in the genome of human.


ZN135_HUMAN Zinc finger protein 135 (sprot)

A zinc finger protein 135 that is encoded in the genome of human.


ZN138_HUMAN Zinc finger protein 138 (sprot)

A zinc finger protein 138 that is encoded in the genome of human.


ZN445_HUMAN Zinc finger protein 445 (sprot)

A zinc finger protein 445 that is encoded in the genome of human.


ZN200_HUMAN Zinc finger protein 200 (sprot)

A zinc finger protein 200 that is encoded in the genome of human.


ZNF45_HUMAN Zinc finger protein 45 (sprot)

A zinc finger protein 45 that is encoded in the genome of human.


ZNF92_HUMAN Zinc finger protein 92 (sprot)

A zinc finger protein 92 that is encoded in the genome of human.


ZN33A_HUMAN Zinc finger protein 33A (sprot)

A zinc finger protein 33A that is encoded in the genome of human.


ZN33B_HUMAN Zinc finger protein 33B (sprot)

A zinc finger protein 33B that is encoded in the genome of human.


ZN616_HUMAN Zinc finger protein 616 (sprot)

A zinc finger protein 616 that is encoded in the genome of human.


ZN543_HUMAN Zinc finger protein 543 (sprot)

A zinc finger protein 543 that is encoded in the genome of human.


ZN415_HUMAN Zinc finger protein 415 (sprot)

A zinc finger protein 415 that is encoded in the genome of human.


ZN155_HUMAN Zinc finger protein 155 (sprot)

A zinc finger protein 155 that is encoded in the genome of human.


ZN154_HUMAN Zinc finger protein 154 (sprot)

A zinc finger protein 154 that is encoded in the genome of human.


ZN211_HUMAN Zinc finger protein 211 (sprot)

A zinc finger protein 211 that is encoded in the genome of human.


ZN266_HUMAN Zinc finger protein 266 (sprot)

A zinc finger protein 266 that is encoded in the genome of human.


ZN267_HUMAN Zinc finger protein 267 (sprot)

A zinc finger protein 267 that is encoded in the genome of human.


ZN268_HUMAN Zinc finger protein 268 (sprot)

A zinc finger protein 268 that is encoded in the genome of human.


ZN234_HUMAN Zinc finger protein 234 (sprot)

A zinc finger protein 234 that is encoded in the genome of human.


ZN235_HUMAN Zinc finger protein 235 (sprot)

A zinc finger protein 235 that is encoded in the genome of human.


ZN460_HUMAN Zinc finger protein 460 (sprot)

A zinc finger protein 460 that is encoded in the genome of human.


ZN273_HUMAN Zinc finger protein 273 (sprot)

A zinc finger protein 273 that is encoded in the genome of human.


ZN169_HUMAN Zinc finger protein 169 (sprot)

A zinc finger protein 169 that is encoded in the genome of human.


ZKSC8_HUMAN Zinc finger protein with KRAB and SCAN domains 8 (sprot)

A zinc finger protein with KRAB and SCAN domains 8 that is encoded in the genome of human.


ZN141_HUMAN Zinc finger protein 141 (sprot)

A zinc finger protein 141 that is encoded in the genome of human.


ZNF77_HUMAN Zinc finger protein 77 (sprot)

A zinc finger protein 77 that is encoded in the genome of human.


ZNF79_HUMAN Zinc finger protein 79 (sprot)

A zinc finger protein 79 that is encoded in the genome of human.


ZNF67_HUMAN Putative zinc finger protein 726P1 (sprot)


ZN124_HUMAN Zinc finger protein 124 (sprot)

A zinc finger protein 124 that is encoded in the genome of human.


ZNF74_HUMAN Zinc finger protein 74 (sprot)

A zinc finger protein 74 that is encoded in the genome of human.


ZN699_HUMAN Zinc finger protein 699 (sprot)

A zinc finger protein 699 that is encoded in the genome of human.


ZN791_HUMAN Zinc finger protein 791 (sprot)

A zinc finger protein 791 that is encoded in the genome of human.


ZN792_HUMAN Zinc finger protein 792 (sprot)

A zinc finger protein 792 that is encoded in the genome of human.


ZN528_HUMAN Zinc finger protein 528 (sprot)

A zinc finger protein 528 that is encoded in the genome of human.


ZN718_HUMAN Zinc finger protein 718 (sprot)

A zinc finger protein 718 that is encoded in the genome of human.


ZIK1_HUMAN Zinc finger protein interacting with ribonucleoprotein K (sprot)

A zinc finger protein interacting with ribonucleoprotein K that is encoded in the genome of human.


ZN568_HUMAN Zinc finger protein 568 (sprot)

A zinc finger protein 568 that is encoded in the genome of human.


ZFP69_HUMAN Zinc finger protein 69 homolog (sprot)

A zinc finger protein 69 homolog that is encoded in the genome of human.


Z658B_HUMAN Zinc finger protein 658B (sprot)

A zinc finger protein 658B that is encoded in the genome of human.


Z585B_HUMAN Zinc finger protein 585B (sprot)

A zinc finger protein 585B that is encoded in the genome of human.


ZN394_HUMAN Zinc finger protein 394 (sprot)

A zinc finger protein 394 that is encoded in the genome of human.


ZN667_HUMAN Zinc finger protein 667 (sprot)

A zinc finger protein 667 that is encoded in the genome of human.


ZN311_HUMAN Zinc finger protein 311 (sprot)

A zinc finger protein 311 that is encoded in the genome of human.


KRBX4_HUMAN KRAB domain-containing protein 4 (sprot)

A protein ZNF673 that is encoded in the genome of human.


ZN484_HUMAN Zinc finger protein 484 (sprot)

A zinc finger protein 484 that is encoded in the genome of human.


ZN506_HUMAN Zinc finger protein 506 (sprot)

A zinc finger protein 506 that is encoded in the genome of human.


ZN569_HUMAN Zinc finger protein 569 (sprot)

A zinc finger protein 569 that is encoded in the genome of human.


ZN678_HUMAN Zinc finger protein 678 (sprot)

A zinc finger protein 678 that is encoded in the genome of human.


ZN684_HUMAN Zinc finger protein 684 (sprot)

A zinc finger protein 684 that is encoded in the genome of human.


ZN697_HUMAN Zinc finger protein 697 (sprot)

A zinc finger protein 697 that is encoded in the genome of human.


ZN658_HUMAN Zinc finger protein 658 (sprot)

A zinc finger protein 658 that is encoded in the genome of human.


ZN468_HUMAN Zinc finger protein 468 (sprot)

A zinc finger protein 468 that is encoded in the genome of human.


ZN691_HUMAN Zinc finger protein 691 (sprot)

A zinc finger protein 691 that is encoded in the genome of human.


ZN776_HUMAN Zinc finger protein 776 (sprot)

A zinc finger protein 776 that is encoded in the genome of human.


ZN626_HUMAN Zinc finger protein 626 (sprot)

A zinc finger protein 626 that is encoded in the genome of human.


ZN772_HUMAN Zinc finger protein 772 (sprot)

A zinc finger protein 772 that is encoded in the genome of human.


Z324B_HUMAN Zinc finger protein 324B (sprot)

A zinc finger protein 324B that is encoded in the genome of human.


ZN660_HUMAN Zinc finger protein 660 (sprot)

A zinc finger protein 660 that is encoded in the genome of human.


ZN470_HUMAN Zinc finger protein 470 (sprot)

A zinc finger protein 470 that is encoded in the genome of human.


ZN770_HUMAN Zinc finger protein 770 (sprot)

A zinc finger protein 770 that is encoded in the genome of human.


ZN425_HUMAN Zinc finger protein 425 (sprot)

A zinc finger protein 425 that is encoded in the genome of human.


ZSC25_HUMAN Zinc finger and SCAN domain-containing protein 25 (sprot)

A zinc finger and SCAN domain-containing protein 25 that is encoded in the genome of human.


ZN746_HUMAN Zinc finger protein 746 (sprot)

A zinc finger protein 746 that is encoded in the genome of human.


ZN774_HUMAN Zinc finger protein 774 (sprot)

A zinc finger protein 774 that is encoded in the genome of human.


ZN544_HUMAN Zinc finger protein 544 (sprot)

A zinc finger protein 544 that is encoded in the genome of human.


ZN343_HUMAN Zinc finger protein 343 (sprot)

A zinc finger protein 343 that is encoded in the genome of human.


ZN529_HUMAN Zinc finger protein 529 (sprot)

A zinc finger protein 529 that is encoded in the genome of human.


ZFP1_HUMAN Zinc finger protein 1 homolog (sprot)

A zinc finger protein 1 that is encoded in the genome of human.


Z585A_HUMAN Zinc finger protein 585A (sprot)

A zinc finger protein 585A that is encoded in the genome of human.


ZN530_HUMAN Zinc finger protein 530 (sprot)

A zinc finger protein 530 that is encoded in the genome of human.


ZN549_HUMAN Zinc finger protein 549 (sprot)

A zinc finger protein 549 that is encoded in the genome of human.


ZN613_HUMAN Zinc finger protein 613 (sprot)

A zinc finger protein 613 that is encoded in the genome of human.


ZN790_HUMAN Zinc finger protein 790 (sprot)

A zinc finger protein 790 that is encoded in the genome of human.


ZN773_HUMAN Zinc finger protein 773 (sprot)

A zinc finger protein 773 that is encoded in the genome of human.


ZN562_HUMAN Zinc finger protein 562 (sprot)

A zinc finger protein 562 that is encoded in the genome of human.


ZN730_HUMAN Putative zinc finger protein 730 (sprot)

A putative zinc finger protein 730 that is encoded in the genome of human.


ZN782_HUMAN Zinc finger protein 782 (sprot)

A zinc finger protein 782 that is encoded in the genome of human.


ZN517_HUMAN Zinc finger protein 517 (sprot)

A zinc finger protein 517 that is encoded in the genome of human.


ZN793_HUMAN Zinc finger protein 793 (sprot)

A zinc finger protein 793 that is encoded in the genome of human.


ZFP2_HUMAN Zinc finger protein ZFP2 (sprot)

A zinc finger protein ZFP2 that is encoded in the genome of human.


Z705A_HUMAN Zinc finger protein 705A (sprot)

A zinc finger protein 705A that is encoded in the genome of human.


ZN704_HUMAN Zinc finger protein 704 (sprot)

A zinc finger protein 704 that is encoded in the genome of human.


ZN620_HUMAN Zinc finger protein 620 (sprot)

A zinc finger protein 620 that is encoded in the genome of human.


ZN600_HUMAN Zinc finger protein 600 (sprot)

A zinc finger protein 600 that is encoded in the genome of human.


ZN493_HUMAN Zinc finger protein 493 (sprot)

A zinc finger protein 493 that is encoded in the genome of human.


ZN662_HUMAN Zinc finger protein 662 (sprot)

A zinc finger protein 662 that is encoded in the genome of human.


ZN621_HUMAN Zinc finger protein 621 (sprot)

A zinc finger protein 621 that is encoded in the genome of human.


ZN767_HUMAN Protein ZNF767 (sprot)

A protein ZNF767 that is encoded in the genome of human.


ZN771_HUMAN Zinc finger protein 771 (sprot)

A zinc finger protein 771 that is encoded in the genome of human.


ZN627_HUMAN Zinc finger protein 627 (sprot)

A zinc finger protein 627 that is encoded in the genome of human.


KRBX5_HUMAN KRAB domain-containing protein 5 (sprot)

A KRAB domain-containing protein 5 that is encoded in the genome of human.


ZN551_HUMAN Zinc finger protein 551 (sprot)

A zinc finger protein 551 that is encoded in the genome of human.


ZN550_HUMAN Zinc finger protein 550 (sprot)

A zinc finger protein 550 that is encoded in the genome of human.


ZN571_HUMAN Zinc finger protein 571 (sprot)

A zinc finger protein 571 that is encoded in the genome of human.


ZN605_HUMAN Zinc finger protein 605 (sprot)

A zinc finger protein 605 that is encoded in the genome of human.


ZN554_HUMAN Zinc finger protein 554 (sprot)

A zinc finger protein 554 that is encoded in the genome of human.


ZN546_HUMAN Zinc finger protein 546 (sprot)

A zinc finger protein 546 that is encoded in the genome of human.


ZN589_HUMAN Zinc finger protein 589 (sprot)

A zinc finger protein 589 that is encoded in the genome of human.


ZN429_HUMAN Zinc finger protein 429 (sprot)

A zinc finger protein 429 that is encoded in the genome of human.


ZN227_HUMAN Zinc finger protein 227 (sprot)

A zinc finger protein 227 that is encoded in the genome of human.


ZN761_HUMAN Zinc finger protein 761 (sprot)

A zinc finger protein 761 that is encoded in the genome of human.


ZN677_HUMAN Zinc finger protein 677 (sprot)

A zinc finger protein 677 that is encoded in the genome of human.


Z354C_HUMAN Zinc finger protein 354C (sprot)

A zinc finger protein 354C that is encoded in the genome of human.


ZN573_HUMAN Zinc finger protein 573 (sprot)

A zinc finger protein 573 that is encoded in the genome of human.


ZN584_HUMAN Zinc finger protein 584 (sprot)

A zinc finger protein 584 that is encoded in the genome of human.


ZN547_HUMAN Zinc finger protein 547 (sprot)

A zinc finger protein 547 that is encoded in the genome of human.


ZN595_HUMAN Zinc finger protein 595 (sprot)

A zinc finger protein 595 that is encoded in the genome of human.


ZN440_HUMAN Zinc finger protein 440 (sprot)

A zinc finger protein 440 that is encoded in the genome of human.


ZN100_HUMAN Zinc finger protein 100 (sprot)

A zinc finger protein 100 that is encoded in the genome of human.


ZN679_HUMAN Zinc finger protein 679 (sprot)

A zinc finger protein 679 that is encoded in the genome of human.


ZNF34_HUMAN Zinc finger protein 34 (sprot)

A zinc finger protein 34 that is encoded in the genome of human.


ZN101_HUMAN Zinc finger protein 101 (sprot)

A zinc finger protein 101 that is encoded in the genome of human.


ZN567_HUMAN Zinc finger protein 567 (sprot)

A zinc finger protein 567 that is encoded in the genome of human.


ZN710_HUMAN Zinc finger protein 710 (sprot)

A zinc finger protein 710 that is encoded in the genome of human.


ZN619_HUMAN Zinc finger protein 619 (sprot)

A zinc finger protein 619 that is encoded in the genome of human.


ZN786_HUMAN Zinc finger protein 786 (sprot)

A zinc finger protein 786 that is encoded in the genome of human.


ZN664_HUMAN Zinc finger protein 664 (sprot)

A zinc finger protein 664 that is encoded in the genome of human.


ZN561_HUMAN Zinc finger protein 561 (sprot)

A zinc finger protein 561 that is encoded in the genome of human.


ZN655_HUMAN Zinc finger protein 655 (sprot)

A zinc finger protein 655 that is encoded in the genome of human.


ZN433_HUMAN Zinc finger protein 433 (sprot)

A zinc finger protein 433 that is encoded in the genome of human.


ZN676_HUMAN Zinc finger protein 676 (sprot)

A zinc finger protein 676 that is encoded in the genome of human.


ZN611_HUMAN Zinc finger protein 611 (sprot)

A zinc finger protein 611 that is encoded in the genome of human.


ZN713_HUMAN Zinc finger protein 713 (sprot)

A zinc finger protein 713 that is encoded in the genome of human.


ZN614_HUMAN Zinc finger protein 614 (sprot)

A zinc finger protein 614 that is encoded in the genome of human.


ZN615_HUMAN Zinc finger protein 615 (sprot)

A zinc finger protein 615 that is encoded in the genome of human.


ZN441_HUMAN Zinc finger protein 441 (sprot)

A zinc finger protein 441 that is encoded in the genome of human.


ZN709_HUMAN Zinc finger protein 709 (sprot)

A zinc finger protein 709 that is encoded in the genome of human.


ZN557_HUMAN Zinc finger protein 557 (sprot)

A zinc finger protein 557 that is encoded in the genome of human.


ZN454_HUMAN Zinc finger protein 454 (sprot)

A zinc finger protein 454 that is encoded in the genome of human.


ZN565_HUMAN Zinc finger protein 565 (sprot)

A zinc finger protein 565 that is encoded in the genome of human.


ZN610_HUMAN Zinc finger protein 610 (sprot)

A zinc finger protein 610 that is encoded in the genome of human.


ZN383_HUMAN Zinc finger protein 383 (sprot)

A zinc finger protein 383 that is encoded in the genome of human.


ZN114_HUMAN Zinc finger protein 114 (sprot)

A zinc finger protein 114 that is encoded in the genome of human.


ZN485_HUMAN Zinc finger protein 485 (sprot)

A zinc finger protein 485 that is encoded in the genome of human.


ZN439_HUMAN Zinc finger protein 439 (sprot)

A zinc finger protein 439 that is encoded in the genome of human.


ZN540_HUMAN Zinc finger protein 540 (sprot)

A zinc finger protein 540 that is encoded in the genome of human.


ZN248_HUMAN Zinc finger protein 248 (sprot)

A zinc finger protein 248 that is encoded in the genome of human.


ZN740_HUMAN Zinc finger protein 740 (sprot)

A zinc finger protein 740 that is encoded in the genome of human.


ZN738_HUMAN Zinc finger protein 738 (sprot)

A zinc finger protein 738 that is encoded in the genome of human.


ZN548_HUMAN Zinc finger protein 548 (sprot)

A zinc finger protein 548 that is encoded in the genome of human.


ZN680_HUMAN Zinc finger protein 680 (sprot)

A zinc finger protein 680 that is encoded in the genome of human.


ZN555_HUMAN Zinc finger protein 555 (sprot)

A zinc finger protein 555 that is encoded in the genome of human.


ZFP28_HUMAN Zinc finger protein 28 homolog (sprot)

A zinc finger protein 28 homolog that is encoded in the genome of human.


ZN563_HUMAN Zinc finger protein 563 (sprot)

A zinc finger protein 563 that is encoded in the genome of human.


ZN461_HUMAN Zinc finger protein 461 (sprot)

A zinc finger protein 461 that is encoded in the genome of human.


ZN417_HUMAN Zinc finger protein 417 (sprot)

A zinc finger protein 417 that is encoded in the genome of human.


ZN671_HUMAN Zinc finger protein 671 (sprot)

A zinc finger protein 671 that is encoded in the genome of human.


ZN519_HUMAN Zinc finger protein 519 (sprot)

A zinc finger protein 519 that is encoded in the genome of human.


ZN564_HUMAN Zinc finger protein 564 (sprot)

A zinc finger protein 564 that is encoded in the genome of human.


ZN596_HUMAN Zinc finger protein 596 (sprot)

A zinc finger protein 596 that is encoded in the genome of human.


ZN398_HUMAN Zinc finger protein 398 (sprot)

A zinc finger protein 398 that is encoded in the genome of human.


ZN675_HUMAN Zinc finger protein 675 (sprot)

A zinc finger protein 675 that is encoded in the genome of human.


ZN721_HUMAN Zinc finger protein 721 (sprot)

A zinc finger protein 721 that is encoded in the genome of human.


ZN431_HUMAN Zinc finger protein 431 (sprot)

A zinc finger protein 431 that is encoded in the genome of human.


ZN483_HUMAN Zinc finger protein 483 (sprot)

A zinc finger protein 483 that is encoded in the genome of human.


ZN418_HUMAN Zinc finger protein 418 (sprot)

A zinc finger protein 418 that is encoded in the genome of human.


ZFP90_HUMAN Zinc finger protein 90 homolog (sprot)

A zinc finger protein 90 homolog that is encoded in the genome of human.


ZN473_HUMAN Zinc finger protein 473 (sprot)

A zinc finger protein 473 that is encoded in the genome of human.


ZN480_HUMAN Zinc finger protein 480 (sprot)

A zinc finger protein 480 that is encoded in the genome of human.


ZN606_HUMAN Zinc finger protein 606 (sprot)

A zinc finger protein 606 that is encoded in the genome of human.


ZN75C_HUMAN Putative zinc finger protein 75C (sprot)


ZKSC4_HUMAN Zinc finger protein with KRAB and SCAN domains 4 (sprot)

A zinc finger protein with KRAB and SCAN domains 4 that is encoded in the genome of human.


ZN566_HUMAN Zinc finger protein 566 (sprot)

A zinc finger protein 566 that is encoded in the genome of human.


ZN669_HUMAN Zinc finger protein 669 (sprot)

A zinc finger protein 669 that is encoded in the genome of human.


ZN775_HUMAN Zinc finger protein 775 (sprot)

A zinc finger protein 775 that is encoded in the genome of human.


ZN707_HUMAN Zinc finger protein 707 (sprot)

A zinc finger protein 707 that is encoded in the genome of human.


ZN689_HUMAN Zinc finger protein 689 (sprot)

A zinc finger protein 689 that is encoded in the genome of human.


ZN274_HUMAN Neurotrophin receptor-interacting factor homolog (sprot)

A neurotrophin receptor-interacting factor that is encoded in the genome of human.


ZN799_HUMAN Zinc finger protein 799 (sprot)

A zinc finger protein 799 that is encoded in the genome of human.


ZN486_HUMAN Zinc finger protein 486 (sprot)

A zinc finger protein 486 that is encoded in the genome of human.


ZN419_HUMAN Zinc finger protein 419 (sprot)

A zinc finger protein 419 that is encoded in the genome of human.


ZN625_HUMAN Zinc finger protein 625 (sprot)

A zinc finger protein 625 that is encoded in the genome of human.


ZN496_HUMAN Zinc finger protein 496 (sprot)

A zinc finger protein 496 that is encoded in the genome of human.


ZN479_HUMAN Zinc finger protein 479 (sprot)

A zinc finger protein 479 that is encoded in the genome of human.


ZN333_HUMAN Zinc finger protein 333 (sprot)

A zinc finger protein 333 that is encoded in the genome of human.


ZN668_HUMAN Zinc finger protein 668 (sprot)

A zinc finger protein 668 that is encoded in the genome of human.


ZN514_HUMAN Zinc finger protein 514 (sprot)

A zinc finger protein 514 that is encoded in the genome of human.


Z354B_HUMAN Zinc finger protein 354B (sprot)

A zinc finger protein 354B that is encoded in the genome of human.


ZN597_HUMAN Zinc finger protein 597 (sprot)

A zinc finger protein 597 that is encoded in the genome of human.


ZN560_HUMAN Zinc finger protein 560 (sprot)

A zinc finger protein 560 that is encoded in the genome of human.


ZN778_HUMAN Zinc finger protein 778 (sprot)

A zinc finger protein 778 that is encoded in the genome of human.


ZN75A_HUMAN Zinc finger protein 75A (sprot)

A zinc finger protein 75A that is encoded in the genome of human.


ZN681_HUMAN Zinc finger protein 681 (sprot)

A zinc finger protein 681 that is encoded in the genome of human.


ZN714_HUMAN Zinc finger protein 714 (sprot)

A zinc finger protein 714 that is encoded in the genome of human.


ZN641_HUMAN Zinc finger protein 641 (sprot)

A zinc finger protein 641 that is encoded in the genome of human.


ZN583_HUMAN Zinc finger protein 583 (sprot)

A zinc finger protein 583 that is encoded in the genome of human.


ZN558_HUMAN Zinc finger protein 558 (sprot)

A zinc finger protein 558 that is encoded in the genome of human.


ZN582_HUMAN Zinc finger protein 582 (sprot)

A zinc finger protein 582 that is encoded in the genome of human.


ZN570_HUMAN Zinc finger protein 570 (sprot)

A zinc finger protein 570 that is encoded in the genome of human.


ZN285_HUMAN Zinc finger protein 285 (sprot)

A zinc finger protein 285 that is encoded in the genome of human.


ZN599_HUMAN Zinc finger protein 599 (sprot)

A zinc finger protein 599 that is encoded in the genome of human.


ZIM3_HUMAN Zinc finger imprinted 3 (sprot)

A zinc finger imprinted 3 that is encoded in the genome of human.


ZN317_HUMAN Zinc finger protein 317 (sprot)

A zinc finger protein 317 that is encoded in the genome of human.


ZN300_HUMAN Zinc finger protein 300 (sprot)

A zinc finger protein 300 that is encoded in the genome of human.


ZN347_HUMAN Zinc finger protein 347 (sprot)

A zinc finger protein 347 that is encoded in the genome of human.


ZN607_HUMAN Zinc finger protein 607 (sprot)

A zinc finger protein 607 that is encoded in the genome of human.


ZN587_HUMAN Zinc finger protein 587 (sprot)

A zinc finger protein 587 that is encoded in the genome of human.


ZN382_HUMAN Zinc finger protein 382 (sprot)

A zinc finger protein 382 that is encoded in the genome of human.


ZN184_HUMAN Zinc finger protein 184 (sprot)

A zinc finger protein 184 that is encoded in the genome of human.


ZN559_HUMAN Zinc finger protein 559 (sprot)

A zinc finger protein 559 that is encoded in the genome of human.


ZKSC3_HUMAN Zinc finger protein with KRAB and SCAN domains 3 (sprot)

A zinc finger protein with KRAB and SCAN domains 3 that is encoded in the genome of human.


ZN649_HUMAN Zinc finger protein 649 (sprot)

A zinc finger protein 649 that is encoded in the genome of human.


ZN670_HUMAN Zinc finger protein 670 (sprot)

A zinc finger protein 670 that is encoded in the genome of human.


ZNF2_HUMAN Zinc finger protein 2 (sprot)

A zinc finger protein 2 that is encoded in the genome of human.


ZN577_HUMAN Zinc finger protein 577 (sprot)

A zinc finger protein 577 that is encoded in the genome of human.


ZN692_HUMAN Zinc finger protein 692 (sprot)

A zinc finger protein 692 that is encoded in the genome of human.


ZN426_HUMAN Zinc finger protein 426 (sprot)

A zinc finger protein 426 that is encoded in the genome of human.


ZN747_HUMAN Zinc finger protein 747 (sprot)

A zinc finger protein 747 that is encoded in the genome of human.


ZN416_HUMAN Zinc finger protein 416 (sprot)

A zinc finger protein 416 that is encoded in the genome of human.


ZN471_HUMAN Zinc finger protein 471 (sprot)

A zinc finger protein 471 that is encoded in the genome of human.


ZN717_HUMAN Zinc finger protein 717 (sprot)

A zinc finger protein 717 that is encoded in the genome of human.


ZN436_HUMAN Zinc finger protein 436 (sprot)

A zinc finger protein 436 that is encoded in the genome of human.


ZN350_HUMAN Zinc finger protein 350 (sprot)

A zinc finger protein 350 that is encoded in the genome of human.


ZN700_HUMAN Zinc finger protein 700 (sprot)

A zinc finger protein 700 that is encoded in the genome of human.


ZN552_HUMAN Zinc finger protein 552 (sprot)

A zinc finger protein 552 that is encoded in the genome of human.


ZN442_HUMAN Zinc finger protein 442 (sprot)

A zinc finger protein 442 that is encoded in the genome of human.


ZN665_HUMAN Zinc finger protein 665 (sprot)

A zinc finger protein 665 that is encoded in the genome of human.


ZN703_HUMAN Zinc finger protein 703 (sprot)

A zinc finger protein 703 that is encoded in the genome of human.


ZN696_HUMAN Zinc finger protein 696 (sprot)

A zinc finger protein 696 that is encoded in the genome of human.


ZN430_HUMAN Zinc finger protein 430 (sprot)

A zinc finger protein 430 that is encoded in the genome of human.


ZN702_HUMAN Putative zinc finger protein 702 (sprot)

A putative zinc finger protein 702 that is encoded in the genome of human.


ZN556_HUMAN Zinc finger protein 556 (sprot)

A zinc finger protein 556 that is encoded in the genome of human.


ZN287_HUMAN Zinc finger protein 287 (sprot)

A zinc finger protein 287 that is encoded in the genome of human.


Z286A_HUMAN Zinc finger protein 286A (sprot)

A zinc finger protein 286A that is encoded in the genome of human.


ZN160_HUMAN Zinc finger protein 160 (sprot)

A zinc finger protein 160 that is encoded in the genome of human.


ZFP14_HUMAN Zinc finger protein 14 homolog (sprot)

A zinc finger protein 14 homolog that is encoded in the genome of human.


ZN304_HUMAN Zinc finger protein 304 (sprot)

A zinc finger protein 304 that is encoded in the genome of human.


ZN334_HUMAN Zinc finger protein 334 (sprot)

A zinc finger protein 334 that is encoded in the genome of human.


PRDM7_HUMAN Histone-lysine N-methyltransferase PRDM7 (sprot)

A histone-lysine N-methyltransferase PRDM7 that is encoded in the genome of human.


ZN331_HUMAN Zinc finger protein 331 (sprot)

A zinc finger protein 331 that is encoded in the genome of human.


ZNF71_HUMAN Endothelial zinc finger protein induced by tumor necrosis factor alpha (sprot)

An endothelial zinc finger protein induced by tumor necrosis factor alpha that is encoded in the genome of human.


ZN302_HUMAN Zinc finger protein 302 (sprot)

A zinc finger protein 302 that is encoded in the genome of human.


ZN701_HUMAN Zinc finger protein 701 (sprot)

A zinc finger protein 701 that is encoded in the genome of human.


ZN446_HUMAN Zinc finger protein 446 (sprot)

A zinc finger protein 446 that is encoded in the genome of human.


ZSC32_HUMAN Zinc finger and SCAN domain-containing protein 32 (sprot)

A zinc finger and SCAN domain-containing protein 32 that is encoded in the genome of human.


ZN586_HUMAN Zinc finger protein 586 (sprot)

A zinc finger protein 586 that is encoded in the genome of human.


ZN226_HUMAN Zinc finger protein 226 (sprot)

A zinc finger protein 226 that is encoded in the genome of human.


ZN224_HUMAN Zinc finger protein 224 (sprot)

A zinc finger protein 224 that is encoded in the genome of human.


ZIM2_HUMAN Zinc finger imprinted 2 (sprot)

A zinc finger imprinted 2 that is encoded in the genome of human.


ZKSC7_HUMAN Zinc finger protein with KRAB and SCAN domains 7 (sprot)

A zinc finger protein with KRAB and SCAN domains 7 that is encoded in the genome of human.


ZN492_HUMAN Zinc finger protein 492 (sprot)

A zinc finger protein 492 that is encoded in the genome of human.


ZN624_HUMAN Zinc finger protein 624 (sprot)

A zinc finger protein 624 that is encoded in the genome of human.


ZNF70_HUMAN Zinc finger protein 70 (sprot)

A zinc finger protein 70 that is encoded in the genome of human.


ZN282_HUMAN Zinc finger protein 282 (sprot)

A zinc finger protein 282 that is encoded in the genome of human.


ZN230_HUMAN Zinc finger protein 230 (sprot)

A zinc finger protein 230 that is encoded in the genome of human.


ZF69B_HUMAN Zinc finger protein 69 homolog B (sprot)

A zinc finger protein 69 homolog B that is encoded in the genome of human.


ZN112_HUMAN Zinc finger protein 112 (sprot)

A zinc finger protein 112 that is encoded in the genome of human.


ZN180_HUMAN Zinc finger protein 180 (sprot)

A zinc finger protein 180 that is encoded in the genome of human.


ZN225_HUMAN Zinc finger protein 225 (sprot)

A zinc finger protein 225 that is encoded in the genome of human.


ZN223_HUMAN Zinc finger protein 223 (sprot)

A zinc finger protein 223 that is encoded in the genome of human.


ZN222_HUMAN Zinc finger protein 222 (sprot)

A zinc finger protein 222 that is encoded in the genome of human.


ZN221_HUMAN Zinc finger protein 221 (sprot)

A zinc finger protein 221 that is encoded in the genome of human.


ZN215_HUMAN Zinc finger protein 215 (sprot)

A zinc finger protein 215 that is encoded in the genome of human.


ZN214_HUMAN Zinc finger protein 214 (sprot)

A zinc finger protein 214 that is encoded in the genome of human.


ZN777_HUMAN Zinc finger protein 777 (sprot)

A zinc finger protein 777 that is encoded in the genome of human.


ZN490_HUMAN Zinc finger protein 490 (sprot)

A zinc finger protein 490 that is encoded in the genome of human.


ZN443_HUMAN Zinc finger protein 443 (sprot)

A zinc finger protein 443 that is encoded in the genome of human.


ZFP30_HUMAN Zinc finger protein 30 homolog (sprot)

A zinc finger protein 30 homolog that is encoded in the genome of human.


ZN510_HUMAN Zinc finger protein 510 (sprot)

A zinc finger protein 510 that is encoded in the genome of human.


ZKSC5_HUMAN Zinc finger protein with KRAB and SCAN domains 5 (sprot)

A zinc finger protein with KRAB and SCAN domains 5 that is encoded in the genome of human.


ZN256_HUMAN Zinc finger protein 256 (sprot)

A zinc finger protein 256 that is encoded in the genome of human.


ZN257_HUMAN Zinc finger protein 257 (sprot)

A zinc finger protein 257 that is encoded in the genome of human.


ZN337_HUMAN Zinc finger protein 337 (sprot)

A zinc finger protein 337 that is encoded in the genome of human.


ZN711_HUMAN Zinc finger protein 711 (sprot)

A zinc finger protein 711 that is encoded in the genome of human.


ZN175_HUMAN Zinc finger protein 175 (sprot)

A zinc finger protein 175 that is encoded in the genome of human.


ZN706_HUMAN Zinc finger protein 706 (sprot)

A zinc finger protein 706 that is encoded in the genome of human.


ZFP37_HUMAN Zinc finger protein 37 homolog (sprot)

A zinc finger protein 37 that is encoded in the genome of human.


purine-containing compound transmembrane transport

The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.


A imidazolidine-2,4-dione that is 7-(2,5-dioxoimidazolidin-4-yl)heptanoic acid in which the imidazoline ring as substituted at position 3 by a 3-(3-cyclohexyl-3-hydroxypropyl) group.


(10E,12Z)-octadeca-10,12-dienoic acid

An octadeca-10,12-dienoic acid having (10E,12Z)-configuration.


IRS4_HUMAN Insulin receptor substrate 4 (sprot)

An insulin receptor substrate 4 that is encoded in the genome of human.


Aminooxyacetic acid

A member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of gamma-aminobutyric acid in tissues.


Ebselen

A benzoselenazole that is 1,2-benzoselenazol-3-one carrying an additional phenyl substituent at position 2. Acts as a mimic of glutathione peroxidase.


A nucleoside 3',5'-cyclic phosphorothioate having adenine as the nucleobase (the Sp-stereoisomer).


mitotic nuclear membrane reassembly

The mitotic cell cycle process involving ESCRTIII that results in reformation of the nuclear envelope after mitotic nuclear division. In organisms undergoing closed mitosis this involves resealing or 'repair' of the nuclear envelope in the nuclear bridge.


SNX3_HUMAN Sorting nexin-3 (sprot)

A sorting nexin-3 that is encoded in the genome of human.


TBCD_HUMAN Tubulin-specific chaperone D (sprot)

A tubulin-specific chaperone D that is encoded in the genome of human.


TBCE_HUMAN Tubulin-specific chaperone E (sprot)

A tubulin-specific chaperone E that is encoded in the genome of human.


TBCB_HUMAN Tubulin-folding cofactor B (sprot)

A tubulin-folding cofactor B that is encoded in the genome of human.


TBCA_HUMAN Tubulin-specific chaperone A (sprot)

A tubulin-specific chaperone A that is encoded in the genome of human.


TBCC_HUMAN Tubulin-specific chaperone C (sprot)

A tubulin-specific chaperone C that is encoded in the genome of human.


SKAP2_HUMAN Src kinase-associated phosphoprotein 2 (sprot)

A Src kinase-associated phosphoprotein 2 that is encoded in the genome of human.


Lyso-PAF c-18

A 1-alkylglycero-3-phosphocholine in which the alkyl group is specified as octadecyl.


CD151_HUMAN CD151 antigen (sprot)

A CD151 molecule that is encoded in the genome of human.


DYST_HUMAN Dystonin (sprot)

A dystonin that is encoded in the genome of human.


FRAT2_HUMAN GSK-3-binding protein FRAT2 (sprot)

A GSK-3-binding protein FRAT2 that is encoded in the genome of human.


FRAT1_HUMAN Proto-oncogene FRAT1 (sprot)

A proto-oncogene FRAT1 that is encoded in the genome of human.


2'-Deoxy-5-iodo-5'-cytidylic acid

A 2'-deoxycytidine phosphate that is 2'-deoxycytidine-5'-monophosphate in which the hydrogen at position 5 on the cytosine ring is replaced by iodine.


ICT1_HUMAN Large ribosomal subunit protein mL62 (sprot)

An immature colon carcinoma transcript 1 protein that is encoded in the genome of human.


RF1ML_HUMAN Peptide chain release factor 1-like, mitochondrial (sprot)

A peptide chain release factor 1-like, mitochondrial that is encoded in the genome of human.


A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs.


WDR19_HUMAN WD repeat-containing protein 19 (sprot)

A WD repeat-containing protein 19 that is encoded in the genome of human.


WDR35_HUMAN WD repeat-containing protein 35 (sprot)

A WD repeat-containing protein 35 that is encoded in the genome of human.


IF140_HUMAN Intraflagellar transport protein 140 homolog (sprot)

An intraflagellar transport protein 140 that is encoded in the genome of human.


IFT43_HUMAN Intraflagellar transport protein 43 homolog (sprot)

An intraflagellar transport protein 43 homolog that is encoded in the genome of human.


IF122_HUMAN Intraflagellar transport protein 122 homolog (sprot)

An intraflagellar transport protein 122 that is encoded in the genome of human.


TT21B_HUMAN Tetratricopeptide repeat protein 21B (sprot)

A tetratricopeptide repeat protein 21B that is encoded in the genome of human.


CLUA1_HUMAN Clusterin-associated protein 1 (sprot)

A clusterin-associated protein 1 that is encoded in the genome of human.


TRIPB_HUMAN Thyroid receptor-interacting protein 11 (sprot)

A thyroid receptor-interacting protein 11 that is encoded in the genome of human.


IT70A_HUMAN Intraflagellar transport protein 70A (sprot)

A tetratricopeptide repeat protein 30A that is encoded in the genome of human.


PDC6I_HUMAN Programmed cell death 6-interacting protein (sprot)

A programmed cell death 6-interacting protein that is encoded in the genome of human.


ETV4_HUMAN ETS translocation variant 4 (sprot)

An ETS translocation variant 4 that is encoded in the genome of human.


RD23A_HUMAN UV excision repair protein RAD23 homolog A (sprot)

A UV excision repair protein RAD23 homolog A that is encoded in the genome of human.


RD23B_HUMAN UV excision repair protein RAD23 homolog B (sprot)

A UV excision repair protein RAD23 homolog B that is encoded in the genome of human.


TPIP1_HUMAN p53-regulated apoptosis-inducing protein 1 (sprot)

A p53-regulated apoptosis-inducing protein 1 that is encoded in the genome of human.


ZN143_HUMAN Zinc finger protein 143 (sprot)

A zinc finger protein 143 that is encoded in the genome of human.


PO2F2_HUMAN POU domain, class 2, transcription factor 2 (sprot)

A POU domain, class 2, transcription factor 2 that is encoded in the genome of human.


RABEK_HUMAN Rab9 effector protein with kelch motifs (sprot)

A Rab9 effector protein with Kelch motifs that is encoded in the genome of human.


2,6-Diamino-5-hydroxyhexanoic acid

A hydroxylysine that is lysine substituted by a hydroxy group at position 5.


An optically active form of 1-piperideine-6-carboxylate having (S)-configuration.


L-pipecolate

The zwitterion of L-pipecolic acid formed by proton transfer from the carboxy group to nitrogen; major species at pH 7.3.


A piperidinecarboxylate that is the conjugate base of 1-piperideine-2-carboxylic acid.


ABC3A_HUMAN DNA dC->dU-editing enzyme APOBEC-3A (sprot)

A DNA dC->dU-editing enzyme APOBEC-3A that is encoded in the genome of human.


ABC3H_HUMAN DNA dC->dU-editing enzyme APOBEC-3H (sprot)

A DNA dC->dU-editing enzyme APOBEC-3H that is encoded in the genome of human.


ABEC4_HUMAN Putative C->U-editing enzyme APOBEC-4 (sprot)

A putative C->U-editing enzyme APOBEC-4 that is encoded in the genome of human.


ABC3C_HUMAN DNA dC->dU-editing enzyme APOBEC-3C (sprot)

A DNA dC->dU-editing enzyme APOBEC-3C that is encoded in the genome of human.


ABC3B_HUMAN DNA dC->dU-editing enzyme APOBEC-3B (sprot)

A DNA dC->dU-editing enzyme APOBEC-3B that is encoded in the genome of human.


ABEC2_HUMAN C->U-editing enzyme APOBEC-2 (sprot)

A C->U-editing enzyme APOBEC-2 that is encoded in the genome of human.


base-excision repair, AP site formation

The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.


Epyrifenacil

An ethyl ester resulting from the formal condensation of the carboxy group of S-3100-CA with ethanol. It is a proherbicide for S-3100-CA  and exhibits high efficacy against a wide range of broad-leaved weeds and grass weeds.


gamma-Terpinene

One of three isomeric monoterpenes differing in the positions of their two double bonds (alpha- and beta-terpinene being the others). In gamma-terpinene the double bonds are at the 1- and 4-positions of the p-menthane skeleton.


Abietic acid

An abietane diterpenoid that is abieta-7,13-diene substituted by a carboxy group at position 18.


Efonidipine

A racemate comprising of equimolar amounts of (R)- and (S)-efonidipine. It is a antihypertensive drug and a dual T-type and L-type calcium channel blocker.


Sciadopitysin

A biflavonoid that is a 7, 4', 4'''-trimethyl ether derivative of amentoflavone.


Terpinolene

A p-menthadiene with double bonds at positions 1 and 4(8).


beta-Pinene

An isomer of pinene with an exocyclic double bond. It is a component of essential oils from many plants.


Ophiobolin A

A sesterterpenoid that is ophiobolane with a hydroxy group at position 3, oxo groups at positions 5 and 25, double bonds at positions 7-8 and 19-20, and an oxygen link between positions 14 and 18.


ginsenoside F2

A ginsenoside found in Panax species that is dammarane which is substituted by hydroxy groups at the 3beta, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 3 and 20 have been converted to the corresponding beta-D-glucopyranosides, and in which a double bond has been introduced at the 24-25 position.


The 2-(3,4-dihydroxybenzoyl) derivative of 2,4,6-trihydroxybenzoic acid. A metabolite of quercetin, an abundant flavonoid found in edible vegetables, grains and fruits which is used as an ingredient in supplements, beverages, or foods.


GUC2A_HUMAN Guanylin (sprot)

A guanylin that is encoded in the genome of human.


GUC2B_HUMAN Guanylate cyclase activator 2B (sprot)

A guanylate cyclase activator 2B that is encoded in the genome of human.


PAX5_HUMAN Paired box protein Pax-5 (sprot)

A paired box protein PAX-5 that is encoded in the genome of human.


ELF2_HUMAN ETS-related transcription factor Elf-2 (sprot)

An ETS-related transcription factor Elf-2 that is encoded in the genome of human.


LIFR_HUMAN Leukemia inhibitory factor receptor (sprot)

A leukemia inhibitory factor receptor that is encoded in the genome of human.


ELF1_HUMAN ETS-related transcription factor Elf-1 (sprot)

An ETS-related transcription factor Elf-1 that is encoded in the genome of human.


VIGLN_HUMAN Vigilin (sprot)

A vigilin that is encoded in the genome of human.


ANGL3_HUMAN Angiopoietin-related protein 3 (sprot)

An angiopoietin-related protein 3 that is encoded in the genome of human.


ANGL8_HUMAN Angiopoietin-like protein 8 (sprot)

An angiopoietin-like protein 8 that is encoded in the genome of human.


LMF1_HUMAN Lipase maturation factor 1 (sprot)

A lipase maturation factor 1 that is encoded in the genome of human.


LMF2_HUMAN Lipase maturation factor 2 (sprot)

A lipase maturation factor 2 that is encoded in the genome of human.


APOC3_HUMAN Apolipoprotein C-III (sprot)

An apolipoprotein C-III that is encoded in the genome of human.


EPO_HUMAN Erythropoietin (sprot)

An erythropoietin that is encoded in the genome of human.


GDIR1_HUMAN Rho GDP-dissociation inhibitor 1 (sprot)

A Rho GDP-dissociation inhibitor 1 that is encoded in the genome of human.


CC187_HUMAN Coiled-coil domain-containing protein 187 (sprot)

A coiled-coil domain-containing protein 187 that is encoded in the genome of human.


FMNL3_HUMAN Formin-like protein 3 (sprot)

A formin-like protein 3 that is encoded in the genome of human.


FMNL2_HUMAN Formin-like protein 2 (sprot)

A formin-like protein 2 that is encoded in the genome of human.


NIPS2_HUMAN Protein NipSnap homolog 2 (sprot)

A protein NipSnap homolog 2 that is encoded in the genome of human.


GFOD1_HUMAN Glucose-fructose oxidoreductase domain-containing protein 1 (sprot)

A glucose-fructose oxidoreductase domain-containing protein 1 that is encoded in the genome of human.


TRAK2_HUMAN Trafficking kinesin-binding protein 2 (sprot)

A trafficking kinesin-binding protein 2 that is encoded in the genome of human.


MYO19_HUMAN Unconventional myosin-XIX (sprot)

A myosin-XIX that is encoded in the genome of human.


TRAK1_HUMAN Trafficking kinesin-binding protein 1 (sprot)

A trafficking kinesin-binding protein 1 that is encoded in the genome of human.


HGS_HUMAN Hepatocyte growth factor-regulated tyrosine kinase substrate (sprot)

A hepatocyte growth factor-regulated tyrosine kinase substrate that is encoded in the genome of human.


STAM1_HUMAN Signal transducing adapter molecule 1 (sprot)

A signal transducing adapter molecule 1 that is encoded in the genome of human.


STAM2_HUMAN Signal transducing adapter molecule 2 (sprot)

A signal transducing adapter molecule 2 that is encoded in the genome of human.


CLH1_HUMAN Clathrin heavy chain 1 (sprot)

A clathrin heavy chain 1 that is encoded in the genome of human.


SPTB2_HUMAN Spectrin beta chain, non-erythrocytic 1 (sprot)

A spectrin beta chain, non-erythrocytic 1 that is encoded in the genome of human.


DLG5_HUMAN Disks large homolog 5 (sprot)

A disks large homolog 5 that is encoded in the genome of human.


PEAK1_HUMAN Inactive tyrosine-protein kinase PEAK1 (sprot)

An inactive tyrosine-protein kinase PEAK1 that is encoded in the genome of human.


WDR6_HUMAN tRNA (34-2'-O)-methyltransferase regulator WDR6 (sprot)

A WD repeat-containing protein 6 that is encoded in the genome of human.


CAPZB_HUMAN F-actin-capping protein subunit beta (sprot)

An F-actin-capping protein subunit beta that is encoded in the genome of human.


AKA12_HUMAN A-kinase anchor protein 12 (sprot)

An A-kinase anchor protein 12 that is encoded in the genome of human.


TOIP1_HUMAN Torsin-1A-interacting protein 1 (sprot)

A torsin-1A-interacting protein 1 that is encoded in the genome of human.


FLIP1_HUMAN Filamin-A-interacting protein 1 (sprot)

A filamin-A-interacting protein 1 that is encoded in the genome of human.


WHAMM_HUMAN WASP homolog-associated protein with actin, membranes and microtubules (sprot)

A WASP-associated protein with actin, membranes and microtubules that is encoded in the genome of human.


EFHD2_HUMAN EF-hand domain-containing protein D2 (sprot)

An EF-hand domain-containing protein D2 that is encoded in the genome of human.


HINT2_HUMAN Adenosine 5'-monophosphoramidase HINT2 (sprot)

A histidine triad nucleotide-binding protein 2 that is encoded in the genome of human.


ANFY1_HUMAN Rabankyrin-5 (sprot)

A rabankyrin-5 that is encoded in the genome of human.


ADDG_HUMAN Gamma-adducin (sprot)

A gamma-adducin that is encoded in the genome of human.


CRLF1_HUMAN Cytokine receptor-like factor 1 (sprot)

A cytokine receptor-like factor 1 that is encoded in the genome of human.


IL21_HUMAN Interleukin-21 (sprot)

An interleukin-21 that is encoded in the genome of human.


GREB1_HUMAN Protein GREB1 (sprot)

A protein GREB1 that is encoded in the genome of human.


ZN217_HUMAN Zinc finger protein 217 (sprot)

A zinc finger protein 217 that is encoded in the genome of human.


CHD1_HUMAN Chromodomain-helicase-DNA-binding protein 1 (sprot)

A chromodomain-helicase-DNA-binding protein 1 that is encoded in the genome of human.


NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2 (sprot)

A nuclear receptor subfamily 5 group A member 2 that is encoded in the genome of human.


BASP1_HUMAN Brain acid soluble protein 1 (sprot)

A brain acid soluble protein 1 that is encoded in the genome of human.


POTEE_HUMAN POTE ankyrin domain family member E (sprot)

A POTE ankyrin domain family member E that is encoded in the genome of human.


BI2L2_HUMAN Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 (sprot)

A brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 that is encoded in the genome of human.


F169A_HUMAN Soluble lamin-associated protein of 75 kDa (sprot)

A soluble lamin-associated protein of 75 kDa that is encoded in the genome of human.


RHCE_HUMAN Blood group Rh(CE) polypeptide (sprot)

A blood group Rh(CE) polypeptide that is encoded in the genome of human.


RHD_HUMAN Blood group Rh(D) polypeptide (sprot)

A blood group Rh(D) polypeptide that is encoded in the genome of human.


A group obtained by removing the hydroxy group from the hemiacetal function of beta-D-galactosyl-(1->3)-N-acetyl-D-glucosamine.


A group obtained by removing the hydroxy group from the hemiacetal function of beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-D-glucosamine.


PEX16_HUMAN Peroxisomal membrane protein PEX16 (sprot)

A peroxisomal membrane protein PEX16 that is encoded in the genome of human.


PX11B_HUMAN Peroxisomal membrane protein 11B (sprot)

A peroxisomal membrane protein 11B that is encoded in the genome of human.


aldehyde dehydrogenase family 3 member A2 isoform h2 (human)

An aldehyde dehydrogenase family 3 member A2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51648-2.


ATAD1_HUMAN Outer mitochondrial transmembrane helix translocase (sprot)

An outer mitochondrial transmembrane helix translocase that is encoded in the genome of human.


GDAP1_HUMAN Ganglioside-induced differentiation-associated protein 1 (sprot)

A ganglioside-induced differentiation-associated protein 1 that is encoded in the genome of human.


PXMP2_HUMAN Peroxisomal membrane protein 2 (sprot)

A peroxisomal membrane protein 2 that is encoded in the genome of human.


ABCD2_HUMAN ATP-binding cassette sub-family D member 2 (sprot)

An ATP-binding cassette sub-family D member 2 that is encoded in the genome of human.


FIS1_HUMAN Mitochondrial fission 1 protein (sprot)

A mitochondrial fission 1 protein that is encoded in the genome of human.


PXMP4_HUMAN Peroxisomal membrane protein 4 (sprot)

A peroxisomal membrane protein 4 that is encoded in the genome of human.


PRIO_HUMAN Major prion protein (sprot)

A PRNP gene translation product (human) that is encoded by the major prion protein open reading frame, as opposed to the alternate reading frame.


SH2B3_HUMAN SH2B adapter protein 3 (sprot)

An SH2B adapter protein 3 that is encoded in the genome of human.


SLAP1_HUMAN Src-like-adapter (sprot)

A Src-like-adapter that is encoded in the genome of human.


SLAP2_HUMAN Src-like-adapter 2 (sprot)

A Src-like-adapter 2 that is encoded in the genome of human.


An N-glycan group involved in post-translational modification of proteins.


An N-glycan residue involved in post-translational modification of proteins.


An N-acetyl-D-glucosaminyl group derived from beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosamine.


An N-acetyl-D-glucosaminyl group derived from 3-O-sulfo-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosamine


RENT1_HUMAN Regulator of nonsense transcripts 1 (sprot)

A regulator of nonsense transcripts 1 that is encoded in the genome of human.


SMG5_HUMAN Nonsense-mediated mRNA decay factor SMG5 (sprot)

A nonsense-mediated mRNA decay factor SMG5 that is encoded in the genome of human.


SMG7_HUMAN Nonsense-mediated mRNA decay factor SMG7 (sprot)

A nonsense-mediated mRNA decay factor SMG7 that is encoded in the genome of human.


PNRC2_HUMAN Proline-rich nuclear receptor coactivator 2 (sprot)

A proline-rich nuclear receptor coactivator 2 that is encoded in the genome of human.


SAMP_HUMAN Serum amyloid P-component (sprot)

A serum amyloid P-component that is encoded in the genome of human.


CALB1_HUMAN Calbindin (sprot)

A calbindin that is encoded in the genome of human.


SORL_HUMAN Sortilin-related receptor (sprot)

A sortilin-related receptor that is encoded in the genome of human.


TSN15_HUMAN Tetraspanin-15 (sprot)

A tetraspanin-15 that is encoded in the genome of human.


TSN5_HUMAN Tetraspanin-5 (sprot)

A tetraspanin-5 that is encoded in the genome of human.


TSN33_HUMAN Tetraspanin-33 (sprot)

A tetraspanin-33 that is encoded in the genome of human.


AKP8L_HUMAN A-kinase anchor protein 8-like (sprot)

An A-kinase anchor protein 8-like that is encoded in the genome of human.


PSIP1_HUMAN PC4 and SFRS1-interacting protein (sprot)

A PC4 and SFRS1-interacting protein that is encoded in the genome of human.


KMT2B_HUMAN Histone-lysine N-methyltransferase 2B (sprot)

A histone-lysine N-methyltransferase 2B that is encoded in the genome of human.


RNA polymerase III type 2 promoter sequence-specific DNA binding

Binding to a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.


transcription factor TFIIIC complex

biolink:CellularComponent biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.


RNA polymerase III type 1 promoter sequence-specific DNA binding

Binding to a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.


SOMA_HUMAN Somatotropin (sprot)

A somatotropin that is encoded in the genome of human.


SOM2_HUMAN Growth hormone variant (sprot)

A growth hormone variant that is encoded in the genome of human.


CORVET complex

A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.


multivesicular body assembly

The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.


regulation of translational termination

Any process that modulates the frequency, rate or extent of translational termination.


mRNA pseudouridine synthesis

The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.


luminal surveillance complex

A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.


primary cell septum

A cell septum that forms following nuclear division.


mitochondrial proton-transporting ATP synthase, catalytic core

The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.


Nem1-Spo7 phosphatase complex

A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.


positive regulation of hydrogen sulfide biosynthetic process

Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.


cysteine biosynthetic process via cystathionine

The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.


regulation of (1->6)-beta-D-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.


negative regulation of glycogen biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.


positive regulation of mitochondrial DNA replication

Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.


dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex

A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p.


dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex

A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p.


nicotinamide riboside transmembrane transporter activity

Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.


nicotinamide riboside transport

The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


Bfa1-Bub2 complex

A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.


asymmetric protein localization to new mitotic spindle pole body

Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically.


3'-flap-structured DNA binding

Binding to a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.


5'-flap-structured DNA binding

Binding to a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.


double-strand break repair via single-strand annealing, removal of nonhomologous ends

During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.


Cdc50p-Drs2p complex

A protein complex that functions as a phospholipid-translocating P-Type ATPase. In budding yeast, this complex consists of Cdc50p and Drs2p proteins, and is involved in the trafficking of transport vesicles between the late Golgi and the early endosome.


mating type switching

The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.


generation of catalytic spliceosome for second transesterification step

Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.


post-mRNA release spliceosomal complex

A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, either U2 or U12, U5, and either U6 or U6atac.


U2-type catalytic step 2 spliceosome

A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.


U2-type catalytic step 1 spliceosome

A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.


first spliceosomal transesterification activity

Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.


intronic box C/D RNA processing

Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.


nuclear-transcribed mRNA catabolic process, RNase MRP-dependent

A minor MRP-dependent nuclear-transcribed mRNA degradation pathway that begins with an endonucleolytic cleavage to generate unprotected ends.


regulation of mitotic sister chromatid segregation

Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.


formation of cytoplasmic translation initiation complex

Joining of the large ribosomal subunit with the translation preinitiation complex, with release of IF2/eIF2 and IF3/eIF3 or IF5B/eIF5B. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.


eukaryotic 43S preinitiation complex

A protein complex composed of the 40S ribosomal subunit plus eIF1, eIF1A, eIF3, eIF5, and eIF2-GTP-bound methionyl-initiator methionine tRNA.


translation reinitiation

A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon.


formation of translation initiation ternary complex

Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).


cytochrome c-heme linkage

The linkage of cytochromes and other heme proteins to heme.


holocytochrome-c synthase activity

Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.


establishment of protein localization to plasma membrane

The directed movement of a protein to a specific location in a plasma membrane.


outer plaque of spindle pole body

One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm.


mitotic spindle astral microtubule end

Any microtubule end that is part of a mitotic spindle astral microtubule.


microtubule lateral binding

Binding to the side of a microtubule.


gamma-tubulin complex localization to cytoplasmic side of mitotic spindle pole body

Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at the cytoplasmic side of the mitotic spindle pole body.