KCMA1_HUMAN Calcium-activated potassium channel subunit alpha-1 (sprot)

A calcium-activated potassium channel subunit alpha-1 that is encoded in the genome of human.


Q5D1E9_STAAU Penicillin-binding protein 4 (trembl)


Biapenem

A carbapenem antibiotic in which the azetidine and pyrroline rings carry 1-hydroxymethyl and pyrazolo[1,2-a][1,2,4]triazolium-6-ylthio substituents respectively.


A1KS91_NEIMF Penicillin-binding protein 1A (trembl)


PD2R2_HUMAN Prostaglandin D2 receptor 2 (sprot)

A prostaglandin D2 receptor DP2 that is encoded in the genome of human.


DHRS9_HUMAN Dehydrogenase/reductase SDR family member 9 (sprot)

A dehydrogenase/reductase SDR family member 9 that is encoded in the genome of human.


RDH5_HUMAN Retinol dehydrogenase 5 (sprot)

A retinol dehydrogenase 5 that is encoded in the genome of human.


ACH10_HUMAN Neuronal acetylcholine receptor subunit alpha-10 (sprot)

A neuronal acetylcholine receptor subunit alpha-10 that is encoded in the genome of human.


Pentolinium

A nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.

A dication whose structure comprises a pentane backbone linking two 1-methylpyrrolidinium groups; a nicotinic antagonist used as a ganglionic blocking agent in hypertension.


DYR_HUMAN Dihydrofolate reductase (sprot)

A dihydrofolate reductase that is encoded in the genome of human.


Iclaprim

An aminopyrimidine that is 5-methylpyrimidine-2,4-diamine in which one of the hydrogens of the methyl group has been replaced by a 2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl group.


Cycloguanil

the active metabolite of proguanil; antifolate drug

A triazine in which a 1,6-dihydro-1,3,5-triazine ring is substituted at N-1 by a 4-chlorophenyl group, at C-2 and -4 by amino groups and at C-6 by gem-dimethyl groups. A dihydrofolate reductase inhibitor, it is a metabolite of the antimalarial drug proguanil.


FOLC_HUMAN Folylpolyglutamate synthase, mitochondrial (sprot)

A folylpolyglutamate synthase, mitochondrial that is encoded in the genome of human.


DDC_HUMAN Aromatic-L-amino-acid decarboxylase (sprot)

An aromatic-L-amino-acid decarboxylase that is encoded in the genome of human.


OPRD_HUMAN Delta-type opioid receptor (sprot)

A delta-type opioid receptor that is encoded in the genome of human.


ANPRA_HUMAN Atrial natriuretic peptide receptor 1 (sprot)

An atrial natriuretic peptide receptor 1 that is encoded in the genome of human.


SSR2_HUMAN Somatostatin receptor type 2 (sprot)

A somatostatin receptor type 2 that is encoded in the genome of human.


Somatostatine

A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.

A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14.


SSR5_HUMAN Somatostatin receptor type 5 (sprot)

A somatostatin receptor type 5 that is encoded in the genome of human.


ABCBB_HUMAN Bile salt export pump (sprot)

A bile salt export pump that is encoded in the genome of human.


MRP7_HUMAN ATP-binding cassette sub-family C member 10 (sprot)

An ATP-binding cassette sub-family C member 10 that is encoded in the genome of human.


PTGIS_HUMAN Prostacyclin synthase (sprot)

A prostacyclin synthase that is encoded in the genome of human.


Oxyphenbutazone

A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)

A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.


DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (sprot)

A DNA (cytosine-5)-methyltransferase 3B that is encoded in the genome of human.


Q50575_MYCTX Bifunctional pyrazinamidase/nicotinamidase (trembl)


Q0IJY2_PLAMA Bifunctional dihydrofolate reductase-thymidylate synthase (trembl)


DRTS_PLAVI Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)


ADK_HUMAN Adenosine kinase (sprot)

An adenosine kinase that is encoded in the genome of human.


IMDH1_HUMAN Inosine-5'-monophosphate dehydrogenase 1 (sprot)

An inosine-5'-monophosphate dehydrogenase 1 that is encoded in the genome of human.


M2_I60A0 Matrix protein 2 (sprot)

An influenzavirus matrix protein 2 that is encoded in the genome of the H2N2 strain A/Ann Arbor/6/1960.


AOFB_HUMAN Amine oxidase [flavin-containing] B (sprot)

An amine oxidase [flavin-containing] B that is encoded in the genome of human.


Tioxolone

A 1,3-benzoxathiole having a hydroxy substituent at the 6-position.


Beta-Sitosterol

used as tranquillizer; sedative; or anticonvulsant; structure

A member of the class of phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3.


Hymecromone

A coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID.

A hydroxycoumarin that is umbelliferone substituted by a methyl group at position 4.


Debrisoquine

An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.


PYRD_PLAF7 Dihydroorotate dehydrogenase (quinone), mitochondrial (sprot)


5HT1F_HUMAN 5-hydroxytryptamine receptor 1F (sprot)

A 5-hydroxytryptamine receptor 1F that is encoded in the genome of human.


ESR2_HUMAN Estrogen receptor beta (sprot)

An estrogen receptor beta that is encoded in the genome of human.


Androstenediol

An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).

A 3beta-hydroxy-Delta(5)-steroid that is 3beta-hydroxyandrost-5-ene carrying an additional hydroxy group at position 17beta.


VKOR1_HUMAN Vitamin K epoxide reductase complex subunit 1 (sprot)

A vitamin K epoxide reductase complex subunit 1 that is encoded in the genome of human.


Phenindione

An indandione that has been used as an anticoagulant. Phenindione has actions similar to WARFARIN, but it is now rarely employed because of its higher incidence of severe adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)


Ethyl biscoumacetate

A coumarin that is used as an anticoagulant. It has actions similar to those of WARFARIN. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)


POL_HV1A2 Gag-Pol polyprotein (sprot)

A lentivirus-type gag-pol polyprotein that is encoded in the genome of Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2).


DCK_HUMAN Deoxycytidine kinase (sprot)

A deoxycytidine kinase that is encoded in the genome of human.


Retigabine

It is a first-in-class anticonvulsant that works by activating KCNQ2/3 channels. In vitro studies indicate that ezogabine enhances transmembrane potassium currents mediated by the KCNQ (Kv7.2 to 7.5) family of ion channels. By activating KCNQ channels, ezogabine is thought to stabilize the resting membrane potential and reduce brain excitability.

A substituted aniline that is benzene-1,2,4-triamine bearing ethoxycarbonyl and 4-fluorobenzyl substituents at positions N-1 and N-4 respectively. An  anticonvulsant used to treat seizures associated with epilepsy in adults.


ADCY1_HUMAN Adenylate cyclase type 1 (sprot)

An adenylate cyclase type 1 that is encoded in the genome of human.


Q60FU1_HAEIF Peptidoglycan D,D-transpeptidase FtsI (trembl)


NQO1_HUMAN NAD(P)H dehydrogenase [quinone] 1 (sprot)

An NAD(P)H dehydrogenase [quinone] 1 that is encoded in the genome of human.


AOFA_HUMAN Amine oxidase [flavin-containing] A (sprot)

An amine oxidase [flavin-containing] A that is encoded in the genome of human.


ALDR_HUMAN Aldo-keto reductase family 1 member B1 (sprot)

An aldo-keto reductase family 1 member B1 that is encoded in the genome of human.


NMDE2_HUMAN Glutamate receptor ionotropic, NMDA 2B (sprot)

A glutamate receptor ionotropic, NMDA 2B that is encoded in the genome of human.


NMDE3_HUMAN Glutamate receptor ionotropic, NMDA 2C (sprot)

A glutamate receptor ionotropic, NMDA 2C that is encoded in the genome of human.


GABT_HUMAN 4-aminobutyrate aminotransferase, mitochondrial (sprot)

A 4-aminobutyrate aminotransferase, mitochondrial that is encoded in the genome of human.


CAH9_HUMAN Carbonic anhydrase 9 (sprot)

A carbonic anhydrase 9 that is encoded in the genome of human.


DPOLA_HUMAN DNA polymerase alpha catalytic subunit (sprot)

A DNA polymerase alpha catalytic subunit that is encoded in the genome of human.


ADA_HUMAN Adenosine deaminase (sprot)

An adenosine deaminase that is encoded in the genome of human.


AQP1_HUMAN Aquaporin-1 (sprot)

An aquaporin-1 that is encoded in the genome of human.


TBB5_HUMAN Tubulin beta chain (sprot)

A tubulin beta chain that is encoded in the genome of human.


PLMN_HUMAN Plasminogen (sprot)

A plasminogen that is encoded in the genome of human.


LSHR_HUMAN Lutropin-choriogonadotropic hormone receptor (sprot)

A lutropin-choriogonadotropic hormone receptor that is encoded in the genome of human.


Buserelin

A potent synthetic analog of GONADOTROPIN-RELEASING HORMONE with D-serine substitution at residue 6, glycine10 deletion, and other modifications.


ALDH2_HUMAN Aldehyde dehydrogenase, mitochondrial (sprot)

An aldehyde dehydrogenase, mitochondrial that is encoded in the genome of human.


A synthetic prostaglandin F2alpha analog. The compound has luteolytic effects and is used for the synchronization of estrus in cattle


PE2R3_HUMAN Prostaglandin E2 receptor EP3 subtype (sprot)

A prostaglandin E2 receptor EP3 subtype that is encoded in the genome of human.


Fluprostenol

Synthetic prostaglandin alpha analog used as an abortifacient

An organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea.


GNRHR_HUMAN Gonadotropin-releasing hormone receptor (sprot)

A gonadotropin-releasing hormone I receptor that is encoded in the genome of human.


Deslorelin

Ovuplant is tradename for short-term-release implant containing deslorelin acetate


AK1C1_HUMAN Aldo-keto reductase family 1 member C1 (sprot)

An aldo-keto reductase family 1 member C1 that is encoded in the genome of human.


CPT1A_HUMAN Carnitine O-palmitoyltransferase 1, liver isoform (sprot)

A carnitine O-palmitoyltransferase 1, liver isoform that is encoded in the genome of human.


DHPS_ECOLI Dihydropteroate synthase (sprot)

A dihydropteroate synthase that is encoded in the genome of Escherichia coli K-12.


Sulfaphenazole

A sulfonamide that is sulfanilamide in which the sulfonamide nitrogen is substituted by a 1-phenyl-1H-pyrazol-5-yl group. It is a selective inhibitor of cytochrome P450 (CYP) 2C9 isozyme, and antibacterial agent.


Sulfalene

Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.


Sulfameter

Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.

A sulfonamide consisting of pyrimidine having a methoxy substituent at the 5-position and a 4-aminobenzenesulfonamido group at the 2-position.


THIL_HUMAN Acetyl-CoA acetyltransferase, mitochondrial (sprot)

An acetyl-CoA acetyltransferase, mitochondrial that is encoded in the genome of human.


LOX5_HUMAN Polyunsaturated fatty acid 5-lipoxygenase (sprot)

A polyunsaturated fatty acid 5-lipoxygenase that is encoded in the genome of human.


PERT_HUMAN Thyroid peroxidase (sprot)

A thyroid peroxidase that is encoded in the genome of human.


HPPK_MYCTO 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (sprot)


HCAR3_HUMAN Hydroxycarboxylic acid receptor 3 (sprot)

A hydroxycarboxylic acid receptor 3 that is encoded in the genome of human.


NADC_HUMAN Nicotinate-nucleotide pyrophosphorylase [carboxylating] (sprot)

A nicotinate-nucleotide pyrophosphorylase [carboxylating] that is encoded in the genome of human.


CASP1_HUMAN Caspase-1 (sprot)

A caspase-1 that is encoded in the genome of human.


RORA_HUMAN Nuclear receptor ROR-alpha (sprot)

A nuclear receptor ROR-alpha that is encoded in the genome of human.


ABL1_HUMAN Tyrosine-protein kinase ABL1 (sprot)

A tyrosine-protein kinase ABL1 that is encoded in the genome of human.


KIT_HUMAN Mast/stem cell growth factor receptor Kit (sprot)

A mast/stem cell growth factor receptor that is encoded in the genome of human.


Niclosamide

An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48). Although suggested as a potential treatment for COVID-19 based on its broad antiviral activity, including in vitro activity against coronaviruses, there are no data to support the use of niclosamide in the treatment of COVID-19.

A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.


Elliptinium

synthetic ellipticine deriv; RN given refers to parent cpd; structure given in first source


EGFR_HUMAN Epidermal growth factor receptor (sprot)

An epidermal growth factor receptor that is encoded in the genome of human.


Chromium chloride (CrCl3)

Trivalent chromium is part of glucose tolerance factor, an activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function.

A chromium chloride with the chromium cation in the +3 oxidation state.


TOP1M_HUMAN DNA topoisomerase I, mitochondrial (sprot)

A DNA topoisomerase I, mitochondrial that is encoded in the genome of human.


PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (sprot)

A peroxisome proliferator-activated receptor gamma that is encoded in the genome of human.


Stearic Acid

A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and  plastics.


Behenic Acid

A straight-chain, C22, long-chain saturated fatty acid.


Oleic Acid

An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed)

An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry.


CAH5B_HUMAN Carbonic anhydrase 5B, mitochondrial (sprot)

A carbonic anhydrase 5B, mitochondrial that is encoded in the genome of human.


Kainic acid

(2S-(2 alpha,3 beta,4 beta))-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid. Ascaricide obtained from the red alga Digenea simplex. It is a potent excitatory amino acid agonist at some types of excitatory amino acid receptors and has been used to discriminate among receptor types. Like many excitatory amino acid agonists it can cause neurotoxicity and has been used experimentally for that purpose.


GRIA1_HUMAN Glutamate receptor 1 (sprot)

A glutamate receptor 1 that is encoded in the genome of human.


Cyclothiazide

inhibits the desensitization of AMPA-type receptors; structure

3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.


PDE5A_HUMAN cGMP-specific 3',5'-cyclic phosphodiesterase (sprot)

A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of human.


Sulmazole

An imidazopyridine that is 1H-imidazo[4,5-b]pyridine which is substituted at position 2 by a 2-methoxy-4-(methylsulfinyl)phenyl group. An A1 adenosine receptor antagonist, it was formerly used as a cardiotonic agent.


PDE6A_HUMAN Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (sprot)

A rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha that is encoded in the genome of human.


RXRA_HUMAN Retinoic acid receptor RXR-alpha (sprot)

A retinoic acid receptor RXR-alpha that is encoded in the genome of human.


RXRB_HUMAN Retinoic acid receptor RXR-beta (sprot)

A retinoic acid receptor RXR-beta that is encoded in the genome of human.


RXRG_HUMAN Retinoic acid receptor RXR-gamma (sprot)

A retinoic acid receptor RXR-gamma that is encoded in the genome of human.


Q53I07_9HIV1 Env polyprotein (Fragment) (trembl)


PDE11_HUMAN Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (sprot)

A dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A that is encoded in the genome of human.


PDE1A_HUMAN Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (sprot)

A dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A that is encoded in the genome of human.


ADT2_HUMAN ADP/ATP translocase 2 (sprot)

An ADP/ATP translocase 2 that is encoded in the genome of human.


ADT1_HUMAN ADP/ATP translocase 1 (sprot)

An ADP/ATP translocase 1 that is encoded in the genome of human.


ADT3_HUMAN ADP/ATP translocase 3 (sprot)

An ADP/ATP translocase 3 that is encoded in the genome of human.


PTN1_HUMAN Tyrosine-protein phosphatase non-receptor type 1 (sprot)

A tyrosine-protein phosphatase non-receptor type 1 that is encoded in the genome of human.


TRYPAN BLUE FREE ACID

A diazo-naphthalene sulfonate that is widely used as a stain.

An aminonaphthalenesulfonic acid that is the free acid form of trypan blue dye.


CP17A_HUMAN Steroid 17-alpha-hydroxylase/17,20 lyase (sprot)

A cytochrome P450 17A1 that is encoded in the genome of human.


Isoconazole, (R)-

A racemate comprising equimolar amounts of (R)- and (S)-isoconazole. A broad-spectrum antibacterial drug used (as its nitrate salt) for treatment of dermatomycoses.


Bifonazole

A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections.


RARG_HUMAN Retinoic acid receptor gamma (sprot)

A retinoic acid receptor gamma that is encoded in the genome of human.


CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial (sprot)

A 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial that is encoded in the genome of human.


Arbutin

A monosaccharide derivative that is  hydroquinone attached to a beta-D-glucopyranosyl residue at position 4 via a glycosidic linkage.


TYRO_HUMAN Tyrosinase (sprot)

A tyrosinase that is encoded in the genome of human.


RIR1_HHV11 Ribonucleoside-diphosphate reductase large subunit (sprot)


OXYR_HUMAN Oxytocin receptor (sprot)

An oxytocin receptor that is encoded in the genome of human.


MTOR_HUMAN Serine/threonine-protein kinase mTOR (sprot)

A serine/threonine-protein kinase mTOR that is encoded in the genome of human.


Ridaforolimus

an mTOR inhibitor for the treatment of cancer


ADX_HUMAN Adrenodoxin, mitochondrial (sprot)

An adrenodoxin, mitochondrial that is encoded in the genome of human.


Amprolium

A veterinary coccidiostat that interferes with THIAMINE metabolism

An organic chloride salt having 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium as the counterion. Used for prevention of coccidiosis in poultry and cattle.


S19A2_HUMAN Thiamine transporter 1 (sprot)

A thiamine transporter 1 that is encoded in the genome of human.


TKT_HUMAN Transketolase (sprot)

A transketolase that is encoded in the genome of human.


RET7_HUMAN Retinoid-binding protein 7 (sprot)

A retinoid-binding protein 7 that is encoded in the genome of human.


AL1A1_HUMAN Aldehyde dehydrogenase 1A1 (sprot)

An aldehyde dehydrogenase 1A1 that is encoded in the genome of human.


RLBP1_HUMAN Retinaldehyde-binding protein 1 (sprot)

A retinaldehyde-binding protein 1 that is encoded in the genome of human.


PDE4A_HUMAN cAMP-specific 3',5'-cyclic phosphodiesterase 4A (sprot)

A cAMP-specific 3',5'-cyclic phosphodiesterase 4A that is encoded in the genome of human.


O54286_STAAU Beta-lactam-inducible penicillin-binding protein (trembl)


Q14TG6_HAEIF Peptidoglycan D,D-transpeptidase FtsI (trembl)


LIPP_HUMAN Pancreatic triacylglycerol lipase (sprot)

A pancreatic triacylglycerol lipase that is encoded in the genome of human.


MURA2_ENTFA UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 (sprot)


Q54906_STRPY Penicillin-binding protein (trembl)


SYFA_ECOLI Phenylalanine--tRNA ligase alpha subunit (sprot)

A prokaryotic-type phenylalanine--tRNA ligase alpha subunit that is encoded in the genome of Escherichia coli K-12.


PE2R2_HUMAN Prostaglandin E2 receptor EP2 subtype (sprot)

A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of human.


Rioprostil

A synthetic methylprostaglandin E1 analog that reduces gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. It is effective in the therapy of gastric ulcers and gives significant protection against NSAID-induced gastric mucosal damage. The drug also prevents cyclosporin A-induced damage to endocrine and exocrine pancreatic secretions. It shows a low order of acute toxicity and there is no evidence of embryotoxicity, fetotoxicity, teratogenicity, or mutagenicity in animal studies.


MGA_HUMAN Maltase-glucoamylase (sprot)

A maltase-glucoamylase that is encoded in the genome of human.


UCK1_HUMAN Uridine-cytidine kinase 1 (sprot)

A uridine-cytidine kinase 1 that is encoded in the genome of human.


Albendazole oxide

Albendazole oxide (also known as albendazole sulphoxide and ricobendazole) is a benzimidazole with a broad-spectrum anthelmintic used in veterinary medicine. It is also a metabolite of two other veterinary drugs: netobimin and albendazole. The mechanism of action of ricobendazole (albendazole sulfoxide), ensuring its anthelmintic activity, is associated with selective inhibition of beta-tubulin polymerization. It binds to the colchicine site of tubulin, inhibiting microtubule polymerization. It also exhibits anticancer activity, potentiating the effects of taxanes and inhibiting cell proliferation in breast cancer cells, non-small cell lung cancer (NSCLC) cells, and melanoma cells. Also, albendazole oxide has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.


STS_HUMAN Steryl-sulfatase (sprot)

A steryl-sulfatase that is encoded in the genome of human.


SHBG_HUMAN Sex hormone-binding globulin (sprot)

A sex hormone-binding globulin that is encoded in the genome of human.


Mesterolone

17 beta-Hydroxy-1 alpha-methyl-5 alpha-androstan-3-one. A synthetic steroid with anabolic and androgenic activities.


Mestanolone

non-virilizing androgenic steroid; RN given refers to (5alpha,17beta)-isomer; structure


Pregnenolone succinate

A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.


Gestrinone

A non-estrogenic contraceptive which is a weak progestin with strong anti-progesterone properties. It is effective if used once a week orally or can also be used in intravaginal devices.


Androstenedione

A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.

A 3-oxo Delta(4)-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.


Aldosterone

A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

A pregnane-based steroidal hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.


O96529_MELIC Carboxylic ester hydrolase (trembl)


PSMD1_HUMAN 26S proteasome non-ATPase regulatory subunit 1 (sprot)

A 26S proteasome non-ATPase regulatory subunit 1 that is encoded in the genome of human.


CCR5_HUMAN C-C chemokine receptor type 5 (sprot)

A C-C chemokine receptor type 5 that is encoded in the genome of human.


S2512_HUMAN Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (sprot)

An electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial that is encoded in the genome of human.


AATC_HUMAN Aspartate aminotransferase, cytoplasmic (sprot)

An aspartate aminotransferase, cytoplasmic that is encoded in the genome of human.


ACY2_HUMAN Aspartoacylase (sprot)

An aspartoacylase that is encoded in the genome of human.


ASNS_HUMAN Asparagine synthetase [glutamine-hydrolyzing] (sprot)

An asparagine synthetase [glutamine-hydrolyzing] that is encoded in the genome of human.


ASPH_HUMAN Aspartyl/asparaginyl beta-hydroxylase (sprot)

An aspartyl/asparaginyl beta-hydroxylase that is encoded in the genome of human.


DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial (sprot)

A glutamate dehydrogenase 1, mitochondrial that is encoded in the genome of human.


CEGT_HUMAN Ceramide glucosyltransferase (sprot)

A ceramide glucosyltransferase that is encoded in the genome of human.


BCL2_HUMAN Apoptosis regulator Bcl-2 (sprot)

An apoptosis regulator Bcl-2 that is encoded in the genome of human.


IMDH2_HUMAN Inosine-5'-monophosphate dehydrogenase 2 (sprot)

An inosine-5'-monophosphate dehydrogenase 2 that is encoded in the genome of human.


PD2R_HUMAN Prostaglandin D2 receptor (sprot)

A prostaglandin D2 receptor that is encoded in the genome of human.


SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (sprot)

A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of human.


FLT3_HUMAN Receptor-type tyrosine-protein kinase FLT3 (sprot)

A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of human.


RET_HUMAN Proto-oncogene tyrosine-protein kinase receptor Ret (sprot)

A proto-oncogene tyrosine-protein kinase receptor Ret that is encoded in the genome of human.


TRY1_HUMAN Serine protease 1 (sprot)

A serine protease 1 that is encoded in the genome of human.


DPP4_HUMAN Dipeptidyl peptidase 4 (sprot)

A dipeptidyl peptidase 4 that is encoded in the genome of human.


Hesperetin

A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position.


HPRT_HUMAN Hypoxanthine-guanine phosphoribosyltransferase (sprot)

A hypoxanthine-guanine phosphoribosyltransferase that is encoded in the genome of human.


Fendosal

A benzoindole that is 4,5-dihydro-3H-benzo[e]indole in which the nitrogen is substituted by a 3-carboxy-4-hydroxyphenyl group. A non-narcotic analgesic and non-steroidal anti-inflammatory drug, it has greater analgesic and inflammatory responses than aspirin but with less gastrointestinal toxicity.


PAI1_HUMAN Plasminogen activator inhibitor 1 (sprot)

A plasminogen activator inhibitor 1 that is encoded in the genome of human.


S22A6_HUMAN Solute carrier family 22 member 6 (sprot)

A solute carrier family 22 member 6 that is encoded in the genome of human.


S22A8_HUMAN Organic anion transporter 3 (sprot)

An organic anion transporter 3 that is encoded in the genome of human.


Loxiglumide

cholecystokinin receptor antagonist; RN refers to (+-)-isomer


Dexloxiglumide

a CCK receptor antagonist; structure given in first source


GGT1_HUMAN Glutathione hydrolase 1 proenzyme (sprot)

A glutathione hydrolase 1 proenzyme that is encoded in the genome of human.


GLRB_HUMAN Glycine receptor subunit beta (sprot)

A glycine receptor subunit beta that is encoded in the genome of human.


TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (sprot)

A troponin C, slow skeletal and cardiac muscles that is encoded in the genome of human.


MMP2_HUMAN 72 kDa type IV collagenase (sprot)

A 72 kDa type IV collagenase that is encoded in the genome of human.


KLK1_HUMAN Kallikrein-1 (sprot)

A kallikrein-1 that is encoded in the genome of human.


SSDH_HUMAN Succinate-semialdehyde dehydrogenase, mitochondrial (sprot)

A succinate-semialdehyde dehydrogenase, mitochondrial that is encoded in the genome of human.


AMPN_HUMAN Aminopeptidase N (sprot)

An aminopeptidase N that is encoded in the genome of human.


CASP3_HUMAN Caspase-3 (sprot)

A caspase-3 that is encoded in the genome of human.


PCP_HUMAN Lysosomal Pro-X carboxypeptidase (sprot)

A lysosomal Pro-X carboxypeptidase that is encoded in the genome of human.


PHKG2_HUMAN Phosphorylase b kinase gamma catalytic chain, liver/testis isoform (sprot)

A phosphorylase b kinase gamma catalytic chain, liver/testis isoform that is encoded in the genome of human.


HDAC5_HUMAN Histone deacetylase 5 (sprot)

A histone deacetylase 5 that is encoded in the genome of human.


FABP4_HUMAN Fatty acid-binding protein, adipocyte (sprot)

A fatty acid-binding protein, adipocyte that is encoded in the genome of human.


CDK1_HUMAN Cyclin-dependent kinase 1 (sprot)

A cyclin-dependent kinase 1 that is encoded in the genome of human.


TOP1_HUMAN DNA topoisomerase 1 (sprot)

A type 1B DNA topoisomerase 1 that is encoded in the genome of human.


HDAC2_HUMAN Histone deacetylase 2 (sprot)

A histone deacetylase 2 that is encoded in the genome of human.


CXCR4_HUMAN C-X-C chemokine receptor type 4 (sprot)

A C-X-C chemokine receptor type 4 that is encoded in the genome of human.


PIM1_HUMAN Serine/threonine-protein kinase pim-1 (sprot)

A proto-oncogene serine/threonine-protein kinase Pim-1 that is encoded in the genome of human.


Proglumide

A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.

A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.


Pentagastrin

A synthetic pentapeptide that has effects like gastrin when given parenterally. It stimulates the secretion of gastric acid, pepsin, and intrinsic factor, and has been used as a diagnostic aid.


IGF1R_HUMAN Insulin-like growth factor 1 receptor (sprot)

An insulin-like growth factor 1 receptor that is encoded in the genome of human.


3BHS1_HUMAN 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (sprot)

A 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 that is encoded in the genome of human.


GBA1_HUMAN Lysosomal acid glucosylceramidase (sprot)

A lysosomal acid glucosylceramidase that is encoded in the genome of human.


HNMT_HUMAN Histamine N-methyltransferase (sprot)

A histamine N-methyltransferase that is encoded in the genome of human.


HDAC3_HUMAN Histone deacetylase 3 (sprot)

A histone deacetylase 3 that is encoded in the genome of human.


MTLR_HUMAN Motilin receptor (sprot)

A motilin receptor that is encoded in the genome of human.


RYR1_HUMAN Ryanodine receptor 1 (sprot)

A ryanodine receptor 1 that is encoded in the genome of human.


ACHE_HUMAN Acetylcholine receptor subunit epsilon (sprot)

An acetylcholine receptor subunit epsilon that is encoded in the genome of human.


Anisindione

a synthetic anticoagulant it exercises its therapeutic action by reducing the prothrombin activity of the blood by inhibiting the vitamin K–mediated gamma-carboxylation of precursor proteins

A cyclic beta-diketone consisting of indane-1,3-dione having a 4-methoxyphenyl substituent at the 4-position.


VKGC_HUMAN Vitamin K-dependent gamma-carboxylase (sprot)

A vitamin K-dependent gamma-carboxylase that is encoded in the genome of human.


OPRX_HUMAN Nociceptin receptor (sprot)

A nociceptin receptor that is encoded in the genome of human.


TLR9_HUMAN Toll-like receptor 9 (sprot)

A Toll-like receptor 9 that is encoded in the genome of human.


CYB_PLAFA Cytochrome b (sprot)

A protein that is a translation product of the MT-CYB gene in Plasmodium falciparum.


TPA_HUMAN Tissue-type plasminogen activator (sprot)

A tissue-type plasminogen activator that is encoded in the genome of human.


ELNE_HUMAN Neutrophil elastase (sprot)

A neutrophil elastase that is encoded in the genome of human.


HDAC7_HUMAN Histone deacetylase 7 (sprot)

A histone deacetylase 7 that is encoded in the genome of human.


FGFR3_HUMAN Fibroblast growth factor receptor 3 (sprot)

A fibroblast growth factor receptor 3 that is encoded in the genome of human.


C11B2_HUMAN Cytochrome P450 11B2, mitochondrial (sprot)

A cytochrome P450 11B that is a translation product of the CYP11B2 gene in human.


Fadrozole

A selective aromatase inhibitor effective in the treatment of estrogen-dependent disease including breast cancer.


LOX15_HUMAN Polyunsaturated fatty acid lipoxygenase ALOX15 (sprot)

A polyunsaturated fatty acid lipoxygenase ALOX15 that is encoded in the genome of human.


MMP3_HUMAN Stromelysin-1 (sprot)

A stromelysin-1 that is encoded in the genome of human.


PLK1_HUMAN Serine/threonine-protein kinase PLK1 (sprot)

A serine/threonine-protein kinase PLK1 that is encoded in the genome of human.


GRIK5_HUMAN Glutamate receptor ionotropic, kainate 5 (sprot)

A glutamate receptor ionotropic, kainate 5 that is encoded in the genome of human.


PDE2A_HUMAN cGMP-dependent 3',5'-cyclic phosphodiesterase (sprot)

A cGMP-dependent 3',5'-cyclic phosphodiesterase that is encoded in the genome of human.


GRM5_HUMAN Metabotropic glutamate receptor 5 (sprot)

A metabotropic glutamate receptor 5 that is encoded in the genome of human.


Phosphoserine

The L-enantiomer of O-phosphoserine.


GRM4_HUMAN Metabotropic glutamate receptor 4 (sprot)

A metabotropic glutamate receptor 4 that is encoded in the genome of human.


MK10_HUMAN Mitogen-activated protein kinase 10 (sprot)

A mitogen-activated protein kinase 10 that is encoded in the genome of human.


SYYC_HUMAN Tyrosine--tRNA ligase, cytoplasmic (sprot)

A tyrosine--tRNA ligase, cytoplasmic that is encoded in the genome of human.


DAPK2_HUMAN Death-associated protein kinase 2 (sprot)

A death-associated protein kinase 2 that is encoded in the genome of human.


DHB1_HUMAN 17-beta-hydroxysteroid dehydrogenase type 1 (sprot)

A 17-beta-hydroxysteroid dehydrogenase type 1 that is encoded in the genome of human.


FDFT_HUMAN Squalene synthase (sprot)

A squalene synthase that is encoded in the genome of human.


KPCD_HUMAN Protein kinase C delta type (sprot)

A protein kinase C delta type that is encoded in the genome of human.


ROCK2_HUMAN Rho-associated protein kinase 2 (sprot)

A Rho-associated protein kinase 2 that is encoded in the genome of human.


KPCA_HUMAN Protein kinase C alpha type (sprot)

A protein kinase C alpha type that is encoded in the genome of human.


KSYK_HUMAN Tyrosine-protein kinase SYK (sprot)

A tyrosine-protein kinase SYK that is encoded in the genome of human.


DPYD_HUMAN Dihydropyrimidine dehydrogenase [NADP(+)] (sprot)

A dihydropyrimidine dehydrogenase [NADP(+)] that is encoded in the genome of human.


PPCE_HUMAN Prolyl endopeptidase (sprot)

A prolyl endopeptidase that is encoded in the genome of human.


MYLK2_HUMAN Myosin light chain kinase 2, skeletal/cardiac muscle (sprot)

A myosin light chain kinase 2, skeletal/cardiac muscle that is encoded in the genome of human.


SOAT1_HUMAN Sterol O-acyltransferase 1 (sprot)

A sterol O-acyltransferase 1 that is encoded in the genome of human.


CSK_HUMAN Tyrosine-protein kinase CSK (sprot)

A tyrosine-protein kinase CSK that is encoded in the genome of human.


CATD_HUMAN Cathepsin D (sprot)

A cathepsin D that is encoded in the genome of human.


LYAG_HUMAN Lysosomal alpha-glucosidase (sprot)

A lysosomal alpha-glucosidase that is encoded in the genome of human.


CATG_HUMAN Cathepsin G (sprot)

A cathepsin G that is encoded in the genome of human.


CATB_HUMAN Cathepsin B (sprot)

A cathepsin B that is encoded in the genome of human.


Nitroxoline

A monohydroxyquinoline in which the hydroxy group is positioned at C-8 with a nitro group trans to it at C-5.


TIE2_HUMAN Angiopoietin-1 receptor (sprot)

An angiopoietin-1 receptor that is encoded in the genome of human.


EPHA8_HUMAN Ephrin type-A receptor 8 (sprot)

An ephrin type-A receptor 8 that is encoded in the genome of human.


GRIK3_HUMAN Glutamate receptor ionotropic, kainate 3 (sprot)

A glutamate receptor ionotropic, kainate 3 that is encoded in the genome of human.


KCC2G_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit gamma (sprot)

A calcium/calmodulin-dependent protein kinase type II subunit gamma that is encoded in the genome of human.


AAK1_HUMAN AP2-associated protein kinase 1 (sprot)

An AAK1 gene translation product (human), isoforms h1 and h2.


MARK2_HUMAN Serine/threonine-protein kinase MARK2 (sprot)

A serine/threonine-protein kinase MARK2 that is encoded in the genome of human.


LOX12_HUMAN Polyunsaturated fatty acid lipoxygenase ALOX12 (sprot)

A polyunsaturated fatty acid lipoxygenase ALOX12 that is encoded in the genome of human.


MET_HUMAN Hepatocyte growth factor receptor (sprot)

A hepatocyte growth factor receptor that is encoded in the genome of human.


BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX (sprot)

A cytoplasmic tyrosine-protein kinase BMX that is encoded in the genome of human.


LIMK1_HUMAN LIM domain kinase 1 (sprot)

A LIM domain kinase 1 that is encoded in the genome of human.


KS6A2_HUMAN Ribosomal protein S6 kinase alpha-2 (sprot)

A ribosomal protein S6 kinase alpha-2 that is encoded in the genome of human.


CP2J2_HUMAN Cytochrome P450 2J2 (sprot)

A cytochrome P450 2J2 that is encoded in the genome of human.


CMA1_HUMAN Chymase (sprot)

A chymase that is encoded in the genome of human.


FABP5_HUMAN Fatty acid-binding protein 5 (sprot)

A fatty acid-binding protein 5 that is encoded in the genome of human.


MMP14_HUMAN Matrix metalloproteinase-14 (sprot)

A matrix metalloproteinase-14 that is encoded in the genome of human.


GSTP1_HUMAN Glutathione S-transferase P (sprot)

A glutathione S-transferase P that is encoded in the genome of human.


FKBP4_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP4 (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP4 that is encoded in the genome of human.


CDK5_HUMAN Cyclin-dependent kinase 5 (sprot)

A cyclin-dependent kinase 5 that is encoded in the genome of human.


ST17B_HUMAN Serine/threonine-protein kinase 17B (sprot)

A serine/threonine-protein kinase 17B that is encoded in the genome of human.


STK10_HUMAN Serine/threonine-protein kinase 10 (sprot)

A serine/threonine-protein kinase 10 that is encoded in the genome of human.


RENI_CALJA Renin (sprot)

A renin that is encoded in the genome of Callithrix jacchus.


HMOX2_RAT Heme oxygenase 2 (sprot)

A heme oxygenase 2 that is encoded in the genome of rat.


Q33BM1_RAT G protein-coupled receptor GPR35 (trembl)


GPR35_MOUSE G-protein coupled receptor 35 (sprot)

A G-protein coupled receptor 35 that is encoded in the genome of mouse.


GSHR_PLAF7 Glutathione reductase (sprot)


KPCE_HUMAN Protein kinase C epsilon type (sprot)

A protein kinase C epsilon that is encoded in the genome of human.


AURKC_HUMAN Aurora kinase C (sprot)

An aurora kinase C that is encoded in the genome of human.


PDE9A_HUMAN High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (sprot)

A high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A that is encoded in the genome of human.


KCNN3_HUMAN Small conductance calcium-activated potassium channel protein 3 (sprot)

A small conductance calcium-activated potassium channel protein 3 that is encoded in the genome of human.


EPHA5_HUMAN Ephrin type-A receptor 5 (sprot)

An ephrin type-A receptor 5 that is encoded in the genome of human.


EPHA4_HUMAN Ephrin type-A receptor 4 (sprot)

An ephrin type-A receptor 4 that is encoded in the genome of human.


FA7_HUMAN Coagulation factor VII (sprot)

A coagulation factor VII that is encoded in the genome of human.


HDAC9_HUMAN Histone deacetylase 9 (sprot)

A histone deacetylase 9 that is encoded in the genome of human.


ERR2_HUMAN Steroid hormone receptor ERR2 (sprot)

A steroid hormone receptor ERR2 that is encoded in the genome of human.


GRM7_HUMAN Metabotropic glutamate receptor 7 (sprot)

A metabotropic glutamate receptor 7 that is encoded in the genome of human.


GSTA1_HUMAN Glutathione S-transferase A1 (sprot)

A glutathione S-transferase A1 that is encoded in the genome of human.


PKN1_HUMAN Serine/threonine-protein kinase N1 (sprot)

A serine/threonine-protein kinase N1 that is encoded in the genome of human.


MK03_HUMAN Mitogen-activated protein kinase 3 (sprot)

A mitogen-activated protein kinase 3 that is encoded in the genome of human.


ST17A_HUMAN Serine/threonine-protein kinase 17A (sprot)

A serine/threonine-protein kinase 17A that is encoded in the genome of human.


TNIK_HUMAN TRAF2 and NCK-interacting protein kinase (sprot)

A TRAF2 and NCK-interacting protein kinase that is encoded in the genome of human.


SIR1_HUMAN NAD-dependent protein deacetylase sirtuin-1 (sprot)

An NAD-dependent protein deacetylase sirtuin-1 that is encoded in the genome of human.


I23O1_HUMAN Indoleamine 2,3-dioxygenase 1 (sprot)

An indoleamine 2,3-dioxygenase 1 that is encoded in the genome of human.


Enilconazole

A racemate comprising equimolar amounts of (R)- and (S)-enilconazole. A fungicide used to control a wide range of fungi including Tilletia and Helminthosporium spp. on fruit, vegetables and ornamentals. In veterinary medicine, it is used topically for the treatment of fungal skin infections in cattle, dogs, and horses; it is also used by inhalation for the treatment of aspergillosis in ostriches.


DGLA_HUMAN Diacylglycerol lipase-alpha (sprot)

A diacylglycerol lipase-alpha that is encoded in the genome of human.


SIR2_HUMAN NAD-dependent protein deacetylase sirtuin-2 (sprot)

An NAD-dependent protein deacetylase sirtuin-2 that is encoded in the genome of human.


DPP8_HUMAN Dipeptidyl peptidase 8 (sprot)

A dipeptidyl peptidase 8 that is encoded in the genome of human.


AURKA_HUMAN Aurora kinase A (sprot)

An aurora kinase A that is encoded in the genome of human.


ALK_HUMAN ALK tyrosine kinase receptor (sprot)

An ALK tyrosine kinase receptor that is encoded in the genome of human.


KCNN2_HUMAN Small conductance calcium-activated potassium channel protein 2 (sprot)

A small conductance calcium-activated potassium channel protein 2 that is encoded in the genome of human.


BMP2K_HUMAN BMP-2-inducible protein kinase (sprot)

A BMP-2-inducible protein kinase that is encoded in the genome of human.


MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (sprot)

An induced myeloid leukemia cell differentiation protein Mcl-1 that is encoded in the genome of human.


C1R_HUMAN Complement C1r subcomponent (sprot)

A complement C1r subcomponent that is encoded in the genome of human.


MMP13_HUMAN Collagenase 3 (sprot)

A collagenase 3 that is encoded in the genome of human.


FABPI_HUMAN Fatty acid-binding protein, intestinal (sprot)

A fatty acid-binding protein, intestinal that is encoded in the genome of human.


CLK2_HUMAN Dual specificity protein kinase CLK2 (sprot)

A dual specificity protein kinase CLK2 that is encoded in the genome of human.


CLK3_HUMAN Dual specificity protein kinase CLK3 (sprot)

A dual specificity protein kinase CLK3 that is encoded in the genome of human.


GGPPS_HUMAN Geranylgeranyl pyrophosphate synthase (sprot)

A geranylgeranyl pyrophosphate synthase that is encoded in the genome of human.


M3K4_HUMAN Mitogen-activated protein kinase kinase kinase 4 (sprot)

A mitogen-activated protein kinase kinase kinase 4 that is encoded in the genome of human.


DPP9_HUMAN Dipeptidyl peptidase 9 (sprot)

A dipeptidyl peptidase 9 that is encoded in the genome of human.


CTRB1_HUMAN Chymotrypsinogen B (sprot)

A chymotrypsinogen B that is encoded in the genome of human.


BACE1_HUMAN Beta-secretase 1 (sprot)

A beta-secretase 1 that is encoded in the genome of human.


RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 (sprot)

A receptor-interacting serine/threonine-protein kinase 2 that is encoded in the genome of human.


FOLR2_HUMAN Folate receptor beta (sprot)

A folate receptor beta that is encoded in the genome of human.


KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D (sprot)

A calcium/calmodulin-dependent protein kinase type 1D that is encoded in the genome of human.


STK4_HUMAN Serine/threonine-protein kinase 4 (sprot)

A serine/threonine-protein kinase 4 that is encoded in the genome of human.


DHI1_HUMAN 11-beta-hydroxysteroid dehydrogenase 1 (sprot)

An 11-beta-hydroxysteroid dehydrogenase 1 that is encoded in the genome of human.


Glycyrrhizin

A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.

A  triterpenoid saponin that is the  glucosiduronide derivative of 3beta-hydroxy-11-oxoolean-12-en-30-oic acid.


GRM6_HUMAN Metabotropic glutamate receptor 6 (sprot)

A metabotropic glutamate receptor 6 that is encoded in the genome of human.


EPHA7_HUMAN Ephrin type-A receptor 7 (sprot)

An ephrin type-A receptor 7 that is encoded in the genome of human.


KS6A5_HUMAN Ribosomal protein S6 kinase alpha-5 (sprot)

A ribosomal protein S6 kinase alpha-5 that is encoded in the genome of human.


AL5AP_HUMAN Arachidonate 5-lipoxygenase-activating protein (sprot)

An arachidonate 5-lipoxygenase-activating protein that is encoded in the genome of human.


CAC1F_HUMAN Voltage-dependent L-type calcium channel subunit alpha-1F (sprot)

A voltage-dependent L-type calcium channel subunit alpha-1F that is encoded in the genome of human.


ANM1_HUMAN Protein arginine N-methyltransferase 1 (sprot)

A protein arginine N-methyltransferase 1 that is encoded in the genome of human.


KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase kinase 1 (sprot)

A calcium/calmodulin-dependent protein kinase kinase 1 that is encoded in the genome of human.


G6PD_HUMAN Glucose-6-phosphate 1-dehydrogenase (sprot)

A glucose-6-phosphate 1-dehydrogenase that is encoded in the genome of human.


Piceid

A stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue.


EPHB4_HUMAN Ephrin type-B receptor 4 (sprot)

An ephrin type-B receptor 4 that is encoded in the genome of human.


GPBAR_HUMAN G-protein coupled bile acid receptor 1 (sprot)

A G-protein coupled bile acid receptor 1 that is encoded in the genome of human.


TSSK1_HUMAN Testis-specific serine/threonine-protein kinase 1 (sprot)

A testis-specific serine/threonine-protein kinase 1 that is encoded in the genome of human.


1,3-Benzothiazole substituted at the 2-position with a sulfanyl group.


PSB8_HUMAN Proteasome subunit beta type-8 (sprot)

A proteasome subunit beta type-8 that is encoded in the genome of human.


NK3R_HUMAN Neuromedin-K receptor (sprot)

A neuromedin-K receptor that is encoded in the genome of human.


ABCA1_HUMAN Phospholipid-transporting ATPase ABCA1 (sprot)

A phospholipid-transporting ATPase ABCA1 that is encoded in the genome of human.


AOC1_HUMAN Amiloride-sensitive amine oxidase [copper-containing] (sprot)

An amiloride-sensitive amine oxidase [copper-containing] that is encoded in the genome of human.


ASIC1_HUMAN Acid-sensing ion channel 1 (sprot)

An acid-sensing ion channel 1 that is encoded in the genome of human.


ACV1B_HUMAN Activin receptor type-1B (sprot)

An activin receptor type-1B that is encoded in the genome of human.


ACVR1_HUMAN Activin receptor type-1 (sprot)

An activin receptor type-1 that is encoded in the genome of human.


ALDR_PIG Aldo-keto reductase family 1 member B1 (sprot)

A protein that is a translation product of the AKR1B1 gene in pig.


MAP2_HUMAN Methionine aminopeptidase 2 (sprot)

A methionine aminopeptidase 2 that is encoded in the genome of human.


Fumagillin

empirical formula C25-27H34-37O7, a monoester of decatetraenedioic acid (HOOC-(C=CH)4-COOH and fumagillin (C16-17H25-26O3); FR 65814 lacks the fat

A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees.


Mibolerone

prevents estrus in animals prevents experimental lymphoid leukosis

An androgen that is nalandrone carrying two methyl substituents at positions 7alpha and 17.


ANDR_RAT Androgen receptor (sprot)

An androgen receptor that is encoded in the genome of rat.


Clofenotane

synthetic insecticide used to combat malaria, typhus, and the other insect-borne human diseases

A chlorophenylethane that is 1,1,1-trichloro-2,2-diphenylethane substituted by additional chloro substituents at positions 4 of the phenyl substituents. It is a commonly used organochlorine insecticide.


Promegestone

A synthetic progestin which is useful for the study of progestin distribution and progestin tissue receptors, as it is not bound by transcortin and binds to progesterone receptors with a higher association constant than progesterone.

A progestin consisting of 17beta-propionylestra-4,9-dien-3-one substituted at position 17 by a methyl group.


APEX1_HUMAN DNA-(apurinic or apyrimidinic site) endonuclease (sprot)

A DNA-(apurinic or apyrimidinic site) endonuclease that is encoded in the genome of human.


Lucanthone

One of the SCHISTOSOMICIDES, it has been replaced largely by HYCANTHONE and more recently PRAZIQUANTEL. (From Martindale The Extrapharmacopoeia, 30th ed., p46)

A thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone.


Hycanthone

Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.

A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.


ARBK1_HUMAN Beta-adrenergic receptor kinase 1 (sprot)

A beta-adrenergic receptor kinase 1 that is encoded in the genome of human.


Cefsulodin

A pyridinium-substituted semisynthetic, broad-spectrum antibacterial used especially for Pseudomonas infections in debilitated patients.

A pyridinium-substituted semi-synthetic, broad-spectrum, cephalosporin antibiotic.


CA2D2_HUMAN Voltage-dependent calcium channel subunit alpha-2/delta-2 (sprot)

A voltage-dependent calcium channel subunit alpha-2/delta-2 that is encoded in the genome of human.


CAT_SALTI Chloramphenicol acetyltransferase (sprot)


CDK15_HUMAN Cyclin-dependent kinase 15 (sprot)

A cyclin-dependent kinase 15 that is encoded in the genome of human.


CFTR_HUMAN Cystic fibrosis transmembrane conductance regulator (sprot)

A cystic fibrosis transmembrane conductance regulator that is encoded in the genome of human.


CLCKA_HUMAN Chloride channel protein ClC-Ka (sprot)

A chloride channel protein ClC-Ka that is encoded in the genome of human.


CLCN2_HUMAN Chloride channel protein 2 (sprot)

A chloride channel protein 2 that is encoded in the genome of human.


Gestodene

synthetic steroid with progestational activity; RN given refers to (17alpha)-isomer


DRTS_PLABA Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)


DRTS_PLAFK Bifunctional dihydrofolate reductase-thymidylate synthase (sprot)


EAA2_HUMAN Excitatory amino acid transporter 2 (sprot)

An excitatory amino acid transporter 2 that is encoded in the genome of human.


EAA3_HUMAN Excitatory amino acid transporter 3 (sprot)

An excitatory amino acid transporter 3 that is encoded in the genome of human.


GLRA3_HUMAN Glycine receptor subunit alpha-3 (sprot)

A glycine receptor subunit alpha-3 that is encoded in the genome of human.


GRIA2_RAT Glutamate receptor 2 (sprot)

A glutamate receptor 2 that is encoded in the genome of rat.


GRIA3_HUMAN Glutamate receptor 3 (sprot)

A glutamate receptor 3 that is encoded in the genome of human.


GRM3_HUMAN Metabotropic glutamate receptor 3 (sprot)

A metabotropic glutamate receptor 3 that is encoded in the genome of human.


GRM8_HUMAN Metabotropic glutamate receptor 8 (sprot)

A metabotropic glutamate receptor 8 that is encoded in the genome of human.


GSTK1_HUMAN Glutathione S-transferase kappa 1 (sprot)

A glutathione S-transferase kappa 1 that is encoded in the genome of human.


HYES_HUMAN Bifunctional epoxide hydrolase 2 (sprot)

An epoxide hydrolase 2 that is encoded in the genome of human.


Sodium dodecyl sulfate

An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate.


ISPA_ECOLI Farnesyl diphosphate synthase (sprot)

A farnesyl diphosphate synthase that is encoded in the genome of Escherichia coli K-12.


MP2K7_HUMAN Dual specificity mitogen-activated protein kinase kinase 7 (sprot)

A dual specificity mitogen-activated protein kinase kinase 7 that is encoded in the genome of human.


MTRR_HUMAN Methionine synthase reductase (sprot)

A methionine synthase reductase that is encoded in the genome of human.


DDL_MYCTU D-alanine--D-alanine ligase (sprot)

A D-alanine--D-alanine ligase A that is encoded in the genome of Mycobacterium tuberculosis H37Rv.


ALR_MYCTU Alanine racemase (sprot)

A protein that is a translation product of the alr gene in Mycobacterium tuberculosis H37Rv.


O40239_9PLVG Env polyprotein (Fragment) (trembl)


NPCL1_HUMAN NPC1-like intracellular cholesterol transporter 1 (sprot)

An NPC1-like intracellular cholesterol transporter 1 that is encoded in the genome of human.


PCFT_HUMAN Proton-coupled folate transporter (sprot)

A proton-coupled folate transporter that is encoded in the genome of human.


A phenylalanine-4-hydroxylase that is encoded in the genome of human.


PHOP1_HUMAN Phosphoethanolamine/phosphocholine phosphatase (sprot)

A phosphoethanolamine/phosphocholine phosphatase that is encoded in the genome of human.


PLD1_HUMAN Phospholipase D1 (sprot)

A phospholipase D1 that is encoded in the genome of human.


PLD2_HUMAN Phospholipase D2 (sprot)

A phospholipase D2 that is encoded in the genome of human.


PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B (sprot)

A eukaryotic peptidyl-prolyl cis-trans isomerase B that is encoded in the genome of human.


PYGL_HUMAN Glycogen phosphorylase, liver form (sprot)

A glycogen phosphorylase, liver form that is encoded in the genome of human.


PYGM_RABIT Glycogen phosphorylase, muscle form (sprot)

A glycogen phosphorylase, muscle form that is encoded in the genome of rabbit.


RAC1_HUMAN Ras-related C3 botulinum toxin substrate 1 (sprot)

A Ras-related C3 botulinum toxin substrate 1 that is encoded in the genome of human.


RNAS1_BOVIN Ribonuclease pancreatic (sprot)

A protein that is a translation product of the RNASE1 gene in cow.


RPOB_ECOLI DNA-directed RNA polymerase subunit beta (sprot)

A DNA-directed RNA polymerase subunit beta that is encoded in the genome of Escherichia coli K-12.


SYI1_STAAU Isoleucine--tRNA ligase (sprot)


SYK_HUMAN Lysine--tRNA ligase (sprot)

A eukaryotic-type lysine--tRNA ligase that is encoded in the genome of human.


TN13B_HUMAN Tumor necrosis factor ligand superfamily member 13B (sprot)

A tumor necrosis factor ligand superfamily member 13B that is encoded in the genome of human.


TY3H_HUMAN Tyrosine 3-monooxygenase (sprot)

A tyrosine 3-monooxygenase that is encoded in the genome of human.


TYSY_CANAL Thymidylate synthase (sprot)

A thymidylate synthase that is encoded in the genome of Candida albicans SC5314.


XDH_BOVIN Xanthine dehydrogenase/oxidase (sprot)

A xanthine dehydrogenase/oxidase that is encoded in the genome of cow.


KCNT1_HUMAN Potassium channel subfamily T member 1 (sprot)

A potassium channel subfamily T member 1 that is encoded in the genome of human.


HCN4_HUMAN Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (sprot)

A potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 that is encoded in the genome of human.


TRPA1_HUMAN Transient receptor potential cation channel subfamily A member 1 (sprot)

A transient receptor potential cation channel TRPA1 that is encoded in the genome of human.


Dibutyl Phthalate

A plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.

A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of  butan-1-ol. Although used extensively as a plasticiser, it is a ubiquitous environmental contaminant that poses a risk to humans.


Thymol

A phenol obtained from thyme oil or other volatile oils used as a stabilizer in pharmaceutical preparations, and as an antiseptic (antibacterial or antifungal) agent.

A phenol that is a natural monoterpene derivative of cymene.


Propyphenazone

A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.


TRPM2_HUMAN Transient receptor potential cation channel subfamily M member 2 (sprot)

A transient receptor potential cation channel subfamily M member 2 that is encoded in the genome of human.


TRPM4_HUMAN Transient receptor potential cation channel subfamily M member 4 (sprot)

A transient receptor potential cation channel subfamily M member 4 that is encoded in the genome of human.


GPC6A_HUMAN G-protein coupled receptor family C group 6 member A (sprot)

A G-protein coupled receptor family C group 6 member A that is encoded in the genome of human.


KCNKI_HUMAN Potassium channel subfamily K member 18 (sprot)

A potassium channel subfamily K member 18 that is encoded in the genome of human.


RORG_HUMAN Nuclear receptor ROR-gamma (sprot)

A nuclear receptor ROR-gamma that is encoded in the genome of human.


GLP1R_HUMAN Glucagon-like peptide 1 receptor (sprot)

A glucagon-like peptide 1 receptor that is encoded in the genome of human.


GLR_HUMAN Glucagon receptor (sprot)

A glucagon receptor that is encoded in the genome of human.


MTP_HUMAN Microsomal triglyceride transfer protein large subunit (sprot)

A microsomal triglyceride transfer protein large subunit that is encoded in the genome of human.


Carbon Tetrachloride

A solvent for oils, fats, lacquers, varnishes, rubber waxes, and resins, and a starting material in the manufacturing of organic compounds. Poisoning by inhalation, ingestion or skin absorption is possible and may be fatal. (Merck Index, 11th ed)

A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.


CP2E1_HUMAN Cytochrome P450 2E1 (sprot)

A cytochrome P450 2E1 that is encoded in the genome of human.


ALDR_RAT Aldo-keto reductase family 1 member B1 (sprot)

An aldo-keto reductase family 1 member B1 that is encoded in the genome of rat.


Sulindac sulfone

inhibits K-ras-dependent cyclooxygenase-2; sulfated analog of indomethacin;; CP248 is an antineoplastic agent that fosters microtubule depolymerization

A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps.  Lipoxygenase and Cox-2 inhibitor.


Menadione bisulfite

A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

An organosulfonic acid obtained by formal hydrosulfonation across the 2 and 3 positions of menadione.


LOX15_RABIT Polyunsaturated fatty acid lipoxygenase ALOX15 (sprot)

A protein that is a translation product of the ALOX15 gene in rabbit.


ADA1B_RAT Alpha-1B adrenergic receptor (sprot)

An alpha-1B adrenergic receptor that is encoded in the genome of rat.


MK01_HUMAN Mitogen-activated protein kinase 1 (sprot)

A mitogen-activated protein kinase 1 that is encoded in the genome of human.


5HT1B_RAT 5-hydroxytryptamine receptor 1B (sprot)

A 5-hydroxytryptamine receptor 1B that is encoded in the genome of rat.


BKRB2_HUMAN B2 bradykinin receptor (sprot)

A B2 bradykinin receptor that is encoded in the genome of human.


MC4R_HUMAN Melanocortin receptor 4 (sprot)

A melanocortin receptor 4 that is encoded in the genome of human.


MC5R_HUMAN Melanocortin receptor 5 (sprot)

A melanocortin receptor 5 that is encoded in the genome of human.


CCR4_HUMAN C-C chemokine receptor type 4 (sprot)

A C-C chemokine receptor type 4 that is encoded in the genome of human.


PP2BA_HUMAN Protein phosphatase 3 catalytic subunit alpha (sprot)

A protein phosphatase 3 catalytic subunit alpha that is encoded in the genome of human.


CLTR1_CAVPO Cysteinyl leukotriene receptor 1 (sprot)

A cysteinyl leukotriene receptor 1 that is encoded in the genome of guinea pig.


Cinalukast

2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in the human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.


MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 (sprot)

A dual specificity mitogen-activated protein kinase kinase 2 that is encoded in the genome of human.


ADA1A_RAT Alpha-1A adrenergic receptor (sprot)

An alpha-1A adrenergic receptor that is encoded in the genome of rat.


HRH1_CAVPO Histamine H1 receptor (sprot)


Q7ZJM1_9HIV1 Integrase (Fragment) (trembl)


Cynarine

active principle of the artichoke; functions primarily as a cholagogue and choleretic and also as antilipemic agent

An alkyl caffeate ester obtained by the formal condensation of hydroxy groups at positions 1 and 3 of ()-quinic acid with two molecules of trans-caffeic acid.


DRD2_RAT D(2) dopamine receptor (sprot)

A D(2) dopamine receptor that is encoded in the genome of rat.


5HT1A_RAT 5-hydroxytryptamine receptor 1A (sprot)

A 5-hydroxytryptamine receptor 1A that is encoded in the genome of rat.


CAH4_BOVIN Carbonic anhydrase 4 (sprot)

A carbonic anhydrase 4 that is encoded in the genome of cow.


SC6A3_RAT Sodium-dependent dopamine transporter (sprot)

A sodium-dependent dopamine transporter that is encoded in the genome of rat.


OPRM_CAVPO Mu-type opioid receptor (Fragment) (sprot)


OPRD_MOUSE Delta-type opioid receptor (sprot)

A delta-type opioid receptor that is encoded in the genome of mouse.


PYRD_MOUSE Dihydroorotate dehydrogenase (quinone), mitochondrial (sprot)

A dihydroorotate dehydrogenase (quinone), mitochondrial that is encoded in the genome of mouse.


5HT2A_RAT 5-hydroxytryptamine receptor 2A (sprot)

A 5-hydroxytryptamine receptor 2A that is encoded in the genome of rat.


FABI_STAAR Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (sprot)


OPRK_CAVPO Kappa-type opioid receptor (sprot)

A kappa-type opioid receptor that is encoded in the genome of guinea pig.


SGMR1_RAT Sigma non-opioid intracellular receptor 1 (sprot)

A sigma non-opioid intracellular receptor 1 that is encoded in the genome of rat.


ACES_MOUSE Acetylcholinesterase (sprot)

An acetylcholinesterase that is encoded in the genome of mouse.


Decamethonium

A quaternary ammonium ion that is a depolarising muscle relaxant whose structure comprises a decane-1,10-diamine core in which each amino group carries three methyl substituents.


5HT1D_PIG 5-hydroxytryptamine receptor 1D (Fragment) (sprot)


DYR_ECOLI Dihydrofolate reductase (sprot)

A dihydrofolate reductase folA that is encoded in the genome of Escherichia coli K-12.


Tepoxalin

A hydroxamic acid obtained by formal condensation of the carboxy group of 3-[5-(4-chlorophenyl)-1-(4-methoxyphenyl)pyrazol-3-yl]propanoic acid with the amino group of N-methylhydroxylamine. It is used in veterinary medicine for the control of pain and inflammation caused by musculoskeletal disorders such as hip dysplasia and arthritis in dogs.


PGH1_SHEEP Prostaglandin G/H synthase 1 (sprot)

A prostaglandin G/H synthase 1 that is encoded in the genome of sheep.


5HT7R_MOUSE 5-hydroxytryptamine receptor 7 (sprot)

A 5-hydroxytryptamine receptor 7 that is encoded in the genome of mouse.


TYSY_MOUSE Thymidylate synthase (sprot)

A thymidylate synthase that is encoded in the genome of mouse.


NRAM_I34A1 Neuraminidase (sprot)

A neuraminidase subtype N1 (Influenza A virus) that is encoded in the genome of the H1N1 strain A/Puerto Rico/8/1934.


Carbaryl

A carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly low toxicity from dermal absorption and is used for control of head lice in some countries.

A carbamate ester obtained by the formal condensation of  1-naphthol with methylcarbamic acid.


CLAT_RAT Choline O-acetyltransferase (sprot)

A choline O-acetyltransferase that is encoded in the genome of rat.


ACM2_MOUSE Muscarinic acetylcholine receptor M2 (sprot)

A muscarinic acetylcholine receptor M2 that is encoded in the genome of mouse.


DRD1_RAT D(1A) dopamine receptor (sprot)

A D(1A) dopamine receptor that is encoded in the genome of rat.


CNR1_RAT Cannabinoid receptor 1 (sprot)

A cannabinoid receptor 1 that is encoded in the genome of rat.


Q94F81_MAIZE HD2 type histone deacetylase HDA106 (trembl)


HDAC1_MOUSE Histone deacetylase 1 (sprot)

A histone deacetylase 1 that is encoded in the genome of mouse.


PF2R_BOVIN Prostaglandin F2-alpha receptor (sprot)

A prostaglandin F2-alpha receptor that is encoded in the genome of cow.


Mitoguazone

Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.

A hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine.


DCAM_RAT S-adenosylmethionine decarboxylase proenzyme (sprot)

A SAM decarboxylase proenzyme that is encoded in the genome of rat.


AOC1_RAT Amiloride-sensitive amine oxidase [copper-containing] (sprot)

An amiloride-sensitive amine oxidase [copper-containing] that is encoded in the genome of rat.


ADRB2_CANLF Beta-2 adrenergic receptor (sprot)

A beta-2 adrenergic receptor that is encoded in the genome of dog.


AA2AR_RAT Adenosine receptor A2a (sprot)

An adenosine receptor A2a that is encoded in the genome of rat.


DYR_YEAST Dihydrofolate reductase (sprot)

A dihydrofolate reductase that is encoded in the genome of yeast.


SC6A3_MOUSE Sodium-dependent dopamine transporter (sprot)

A sodium-dependent dopamine transporter that is encoded in the genome of mouse.


5HT2B_RAT 5-hydroxytryptamine receptor 2B (sprot)

A 5-hydroxytryptamine receptor 2B that is encoded in the genome of rat.


HPPD_PIG 4-hydroxyphenylpyruvate dioxygenase (sprot)

A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of pig.


RABP1_CHICK Cellular retinoic acid-binding protein 1 (sprot)

A cellular retinoic acid-binding protein 1 that is encoded in the genome of chicken.


5HT2C_MOUSE 5-hydroxytryptamine receptor 2C (sprot)

A 5-hydroxytryptamine receptor 2C that is encoded in the genome of mouse.


DRD2_MOUSE D(2) dopamine receptor (sprot)

A D(2) dopamine receptor that is encoded in the genome of mouse.


VDR_CHICK Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of chicken.


5HT2C_RAT 5-hydroxytryptamine receptor 2C (sprot)

A 5-hydroxytryptamine receptor 2C that is encoded in the genome of rat.


MTR1B_CHICK Melatonin receptor type 1B (Fragment) (sprot)


ANDR_MOUSE Androgen receptor (sprot)

An androgen receptor that is encoded in the genome of mouse.


TSPO_RAT Translocator protein (sprot)

A protein that is a translation product of the Tspo gene in rat.


CAC1C_RAT Voltage-dependent L-type calcium channel subunit alpha-1C (sprot)

A voltage-dependent L-type calcium channel subunit alpha-1C that is encoded in the genome of rat.


5HT4R_RAT 5-hydroxytryptamine receptor 4 (sprot)

A 5-hydroxytryptamine receptor 4 that is encoded in the genome of rat.


5HT3A_RAT 5-hydroxytryptamine receptor 3A (sprot)

A 5-hydroxytryptamine receptor 3A that is encoded in the genome of rat.


ADA1A_BOVIN Alpha-1A adrenergic receptor (sprot)

An alpha-1A adrenergic receptor that is encoded in the genome of cow.


THB_RAT Thyroid hormone receptor beta (sprot)

A thyroid hormone receptor beta that is encoded in the genome of rat.


Deaminooxytocin

octa-peptide lacking free amino group on cystine residue; RN given refers to cpd without isomeric designation


OXYR_RAT Oxytocin receptor (sprot)

An oxytocin receptor that is encoded in the genome of rat.


ADA2A_PIG Alpha-2A adrenergic receptor (sprot)


ADA2A_BOVIN Alpha-2A adrenergic receptor (sprot)

An alpha-2A adrenergic receptor that is encoded in the genome of cow.


RXRB_MOUSE Retinoic acid receptor RXR-beta (sprot)

A retinoic acid receptor RXR-beta that is encoded in the genome of mouse.


5HT1D_RAT 5-hydroxytryptamine receptor 1D (sprot)

A 5-hydroxytryptamine receptor 1D that is encoded in the genome of rat.


RABP1_MOUSE Cellular retinoic acid-binding protein 1 (sprot)

A cellular retinoic acid-binding protein 1 that is encoded in the genome of mouse.


RABP2_MOUSE Cellular retinoic acid-binding protein 2 (sprot)

A cellular retinoic acid-binding protein 2 that is encoded in the genome of mouse.


RXRA_MOUSE Retinoic acid receptor RXR-alpha (sprot)

A retinoic acid receptor RXR-alpha that is encoded in the genome of mouse.


PTGDS_MOUSE Prostaglandin-H2 D-isomerase (sprot)

A prostaglandin-H2 D-isomerase that is encoded in the genome of mouse.


DRD4_RAT D(4) dopamine receptor (sprot)

A D(4) dopamine receptor that is encoded in the genome of rat.


CAC1D_RAT Voltage-dependent L-type calcium channel subunit alpha-1D (sprot)

A voltage-dependent L-type calcium channel subunit alpha-1D that is encoded in the genome of rat.


SSR3_MOUSE Somatostatin receptor type 3 (sprot)

A somatostatin receptor type 3 that is encoded in the genome of mouse.


SSR4_HUMAN Somatostatin receptor type 4 (sprot)

A somatostatin receptor type 4 that is encoded in the genome of human.


PGH1_RAT Prostaglandin G/H synthase 1 (sprot)

A prostaglandin G/H synthase 1 that is encoded in the genome of rat.


THRB_BOVIN Prothrombin (sprot)

A prothrombin that is encoded in the genome of cow.


PPARA_MOUSE Peroxisome proliferator-activated receptor alpha (sprot)

A peroxisome proliferator-activated receptor alpha that is encoded in the genome of mouse.


Clofibric acid

An antilipemic agent that is the biologically active metabolite of CLOFIBRATE.

A monocarboxylic acid that is isobutyric acid substituted at position 2 by a p-chlorophenoxy group. It is a metabolite of the drug clofibrate.


PPARG_MOUSE Peroxisome proliferator-activated receptor gamma (sprot)

A peroxisome proliferator-activated receptor gamma that is encoded in the genome of mouse.


AOFA_BOVIN Amine oxidase [flavin-containing] A (sprot)

An amine oxidase [flavin-containing] A that is encoded in the genome of cow.


AT1A1_CANLF Sodium/potassium-transporting ATPase subunit alpha-1 (sprot)

A sodium/potassium-transporting ATPase subunit alpha-1 that is encoded in the genome of dog.


HRP1_PLAFA Histidine-rich protein PFHRP-II (sprot)


DYR_CANAX Dihydrofolate reductase (sprot)


S5A2_RAT 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (sprot)

A 3-oxo-5-alpha-steroid 4-dehydrogenase 2 that is encoded in the genome of rat.


ACHA9_RAT Neuronal acetylcholine receptor subunit alpha-9 (sprot)

A neuronal acetylcholine receptor subunit alpha-9 that is encoded in the genome of rat.


PDE5A_RAT cGMP-specific 3',5'-cyclic phosphodiesterase (sprot)

A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of rat.


RARG_MOUSE Retinoic acid receptor gamma (sprot)

A retinoic acid receptor gamma that is encoded in the genome of mouse.


LCAP_RAT Leucyl-cystinyl aminopeptidase (sprot)

A leucyl-cystinyl aminopeptidase that is encoded in the genome of rat.


DRD2_CANLF D(2) dopamine receptor (sprot)

A D(2) dopamine receptor that is encoded in the genome of dog.


PE2R1_MOUSE Prostaglandin E2 receptor EP1 subtype (sprot)

A prostaglandin E2 receptor EP1 subtype that is encoded in the genome of mouse.


PE2R2_MOUSE Prostaglandin E2 receptor EP2 subtype (sprot)

A prostaglandin E2 receptor EP2 subtype that is encoded in the genome of mouse.


PE2R4_MOUSE Prostaglandin E2 receptor EP4 subtype (sprot)

A prostaglandin E2 receptor EP4 subtype that is encoded in the genome of mouse.


KCNN3_RAT Small conductance calcium-activated potassium channel protein 3 (sprot)

A small conductance calcium-activated potassium channel protein 3 that is encoded in the genome of rat.


PTP1_YEAST Tyrosine-protein phosphatase 1 (sprot)

A protein that is a translation product of the PTP1 gene in yeast.


VGLU3_RAT Vesicular glutamate transporter 3 (sprot)

A vesicular glutamate transporter 3 that is encoded in the genome of rat.


ENPP2_HUMAN Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (sprot)

An ectonucleotide pyrophosphatase/phosphodiesterase family member 2 that is encoded in the genome of human.


GSK3A_HUMAN Glycogen synthase kinase-3 alpha (sprot)

A glycogen synthase kinase-3 alpha that is encoded in the genome of human.


S22A6_RAT Solute carrier family 22 member 6 (sprot)

A solute carrier family 22 member 6 that is encoded in the genome of rat.


DRD1_MOUSE D(1A) dopamine receptor (sprot)

A D(1A) dopamine receptor that is encoded in the genome of mouse.


CNR1_MOUSE Cannabinoid receptor 1 (sprot)

A cannabinoid receptor 1 that is encoded in the genome of mouse.


DYR_CHICK Dihydrofolate reductase (sprot)

A dihydrofolate reductase that is encoded in the genome of chicken.


AA1R_BOVIN Adenosine receptor A1 (sprot)

An adenosine receptor A1 that is encoded in the genome of cow.


Q0GKD7_LEIDO Farnesyl pyrophosphate synthase (trembl)


V2R_BOVIN Vasopressin V2 receptor (sprot)

A vasopressin V2 receptor that is encoded in the genome of cow.


TRPV1_RAT Transient receptor potential cation channel subfamily V member 1 (sprot)

A transient receptor potential cation channel TRPV1 that is encoded in the genome of rat.


FAAH1_RAT Fatty-acid amide hydrolase 1 (sprot)

A fatty-acid amide hydrolase 1 that is encoded in the genome of rat.


CCKAR_CAVPO Cholecystokinin receptor type A (sprot)

A protein that is a translation product of the CCKAR gene in guinea pig.


OPRM_BOVIN Mu-type opioid receptor (sprot)

A mu-type opioid receptor that is encoded in the genome of cow.


HCAR2_RAT Hydroxycarboxylic acid receptor 2 (sprot)

A hydroxycarboxylic acid receptor 2 that is encoded in the genome of rat.


AOC3_RAT Membrane primary amine oxidase (sprot)

A membrane primary amine oxidase that is encoded in the genome of rat.


A3EZI9_9HEPC Genome polyprotein (Fragment) (trembl)


ACHB4_RAT Neuronal acetylcholine receptor subunit beta-4 (sprot)

A neuronal acetylcholine receptor subunit beta-4 that is encoded in the genome of rat.


ESR1_RAT Estrogen receptor (sprot)

An estrogen receptor that is encoded in the genome of rat.


BGLR_RAT Beta-glucuronidase (sprot)

A beta-glucuronidase that is encoded in the genome of rat.


LYSC1_RAT Lysozyme C-1 (sprot)

A lysozyme C-2 that is encoded in the genome of rat.


PUR2_HUMAN Trifunctional purine biosynthetic protein adenosine-3 (sprot)

A trifunctional purine biosynthetic protein adenosine-3 that is encoded in the genome of human.


GRM6_RAT Metabotropic glutamate receptor 6 (sprot)

A metabotropic glutamate receptor 6 that is encoded in the genome of rat.


ACM4_RAT Muscarinic acetylcholine receptor M4 (sprot)

A muscarinic acetylcholine receptor M4 that is encoded in the genome of rat.


HNMT_RAT Histamine N-methyltransferase (sprot)

A histamine N-methyltransferase that is encoded in the genome of rat.


SGMR1_MOUSE Sigma non-opioid intracellular receptor 1 (sprot)

A sigma non-opioid intracellular receptor 1 that is encoded in the genome of mouse.


ADA1B_MESAU Alpha-1B adrenergic receptor (sprot)

A protein that is a translation product of the ADRA1B gene in Mesocricetus auratus.


TYSY_RAT Thymidylate synthase (sprot)

A thymidylate synthase that is encoded in the genome of rat.


O30463_MYCAV Dihydrofolate reductase (trembl)


CAH2_RAT Carbonic anhydrase 2 (sprot)

A vertebrate-type carbonic anhydrase 2 that is encoded in the genome of rat.


CAH7_MOUSE Carbonic anhydrase 7 (sprot)

A carbonic anhydrase 7 that is encoded in the genome of mouse.


ESR2_MOUSE Estrogen receptor beta (sprot)

An estrogen receptor beta that is encoded in the genome of mouse.


ESR1_MOUSE Estrogen receptor (sprot)

An estrogen receptor that is encoded in the genome of mouse.


PRGR_RAT Progesterone receptor (sprot)

A progesterone receptor that is encoded in the genome of rat.


AROQ_HELPY 3-dehydroquinate dehydratase (sprot)

A protein that is a translation product of the aroQ gene in Helicobacter pylori 26695.


AROQ_STRCO 3-dehydroquinate dehydratase (sprot)

A protein that is a translation product of the aroQ gene in Streptomyces coelicolor A3(2).


O77773_PIG Calcium voltage-gated channel auxiliary subunit alpha2delta 1 (trembl)


PDE6C_BOVIN Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (sprot)

A cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' that is encoded in the genome of cow.


ENPL_CANLF Endoplasmin (sprot)

An endoplasmin that is encoded in the genome of dog.


LCK_MOUSE Proto-oncogene tyrosine-protein kinase LCK (sprot)

A tyrosine-protein kinase Lck that is encoded in the genome of mouse.


GALE_HUMAN UDP-glucose 4-epimerase (sprot)

A UDP-glucose 4-epimerase that is encoded in the genome of human.


Diisopropyl fluorophosphate

A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.


EST1_PIG Liver carboxylesterase (sprot)

A protein that is a translation product of the CES1 gene in pig.


MAPK2_HUMAN MAP kinase-activated protein kinase 2 (sprot)

A MAP kinase-activated protein kinase 2 that is encoded in the genome of human.


Q6VVP7_PLAFA L-lactate dehydrogenase (trembl)


MDHC_PIG Malate dehydrogenase, cytoplasmic (sprot)

A malate dehydrogenase, cytoplasmic that is encoded in the genome of pig.


BIRC5_HUMAN Baculoviral IAP repeat-containing protein 5 (sprot)

A baculoviral IAP repeat-containing protein 5 that is encoded in the genome of human.


FA10_RABIT Coagulation factor X (sprot)

A coagulation factor X that is encoded in the genome of rabbit.


ACM2_PIG Muscarinic acetylcholine receptor M2 (sprot)

A muscarinic acetylcholine receptor M2 that is encoded in the genome of pig.


VMAT2_BOVIN Synaptic vesicular amine transporter (sprot)

A synaptic vesicular amine transporter that is encoded in the genome of cow.


DHI1_MOUSE 11-beta-hydroxysteroid dehydrogenase 1 (sprot)

An 11-beta-hydroxysteroid dehydrogenase 1 that is encoded in the genome of mouse.


SC5A1_HUMAN Sodium/glucose cotransporter 1 (sprot)

A sodium/glucose cotransporter 1 that is encoded in the genome of human.


GGPPS_YEAST Geranylgeranyl pyrophosphate synthase BTS1 (sprot)

A geranylgeranyl pyrophosphate synthase that is encoded in the genome of yeast.


ALBU_BOVIN Albumin (sprot)

An albumin that is encoded in the genome of cow.


AK1CL_MOUSE Aldo-keto reductase family 1 member C21 (sprot)

An aldo-keto reductase family 1 member C21 that is encoded in the genome of mouse.


S22AC_HUMAN Solute carrier family 22 member 12 (sprot)

A solute carrier family 22 member 12 that is encoded in the genome of human.


BTK_HUMAN Tyrosine-protein kinase BTK (sprot)

A tyrosine-protein kinase BTK that is encoded in the genome of human.


TEC_HUMAN Tyrosine-protein kinase Tec (sprot)

A tyrosine-protein kinase Tec that is encoded in the genome of human.


AK1BA_HUMAN Aldo-keto reductase family 1 member B10 (sprot)

An aldo-keto reductase family 1 member B10 that is encoded in the genome of human.


AGTRA_RAT Type-1 angiotensin II receptor A (sprot)

An angiotensin II receptor 1A that is encoded in the genome of rat.


FABI_BACSU Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (sprot)


CAH15_MOUSE Carbonic anhydrase 15 (sprot)

A carbonic anhydrase 15 that is encoded in the genome of mouse.


GBA2_MOUSE Non-lysosomal glucosylceramidase (sprot)

A non-lysosomal glucosylceramidase that is encoded in the genome of mouse.


PGH1_BOVIN Prostaglandin G/H synthase 1 (sprot)

A prostaglandin G/H synthase 1 that is encoded in the genome of cow.


UFO_HUMAN Tyrosine-protein kinase receptor UFO (sprot)

A tyrosine-protein kinase receptor UFO that is encoded in the genome of human.


TYRO3_HUMAN Tyrosine-protein kinase receptor TYRO3 (sprot)

A tyrosine-protein kinase receptor TYRO3 that is encoded in the genome of human.


KPCD1_HUMAN Serine/threonine-protein kinase D1 (sprot)

A serine/threonine-protein kinase D1 that is encoded in the genome of human.


DHI2_MOUSE 11-beta-hydroxysteroid dehydrogenase type 2 (sprot)

An 11-beta-hydroxysteroid dehydrogenase type 2 that is encoded in the genome of mouse.


AKT2_HUMAN RAC-beta serine/threonine-protein kinase (sprot)

A RAC-beta serine/threonine-protein kinase that is encoded in the genome of human.


CAN_YEAST Carbonic anhydrase (sprot)

A protein that is a translation product of the NCE103 gene in yeast.


CAN_CANAL Carbonic anhydrase (sprot)

A protein that is a translation product of the NCE103 gene in Candida albicans SC5314.


KCNH2_CAVPO Potassium voltage-gated channel subfamily H member 2 (Fragment) (sprot)


BLKPC_KLEPN Carbapenem-hydrolyzing beta-lactamase KPC (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the blaKPC-2 gene in Klebsiella pneumoniae.


PPARG_RAT Peroxisome proliferator-activated receptor gamma (sprot)

A peroxisome proliferator-activated receptor gamma that is encoded in the genome of rat.


B0BL08_ECOLX dihydrofolate reductase (trembl)


GRIA1_RAT Glutamate receptor 1 (sprot)

A glutamate receptor 1 that is encoded in the genome of rat.


GRIA3_RAT Glutamate receptor 3 (sprot)

A glutamate receptor 3 that is encoded in the genome of rat.


ACHA3_RAT Neuronal acetylcholine receptor subunit alpha-3 (sprot)

A neuronal acetylcholine receptor subunit alpha-3 that is encoded in the genome of rat.


PF2R_MOUSE Prostaglandin F2-alpha receptor (sprot)

A prostaglandin F2-alpha receptor that is encoded in the genome of mouse.


Q9XYC7_PLAFA Histone deacetylase (trembl)


GRIK5_RAT Glutamate receptor ionotropic, kainate 5 (sprot)

A glutamate receptor ionotropic, kainate 5 that is encoded in the genome of rat.


5HT2A_PIG 5-hydroxytryptamine receptor 2A (sprot)

A 5-hydroxytryptamine receptor 2A that is encoded in the genome of pig.


NISCH_RAT Nischarin (sprot)

A nischarin that is encoded in the genome of rat.


LYAG_RAT Lysosomal alpha-glucosidase (sprot)

A lysosomal alpha-glucosidase that is encoded in the genome of rat.


TCR2_ECOLX Tetracycline resistance protein, class B (sprot)

A protein that is a translation product of any of the plasmid-encoded copies of the tetA gene in Escherichia coli.


CXCR4_RAT C-X-C chemokine receptor type 4 (sprot)

A C-X-C chemokine receptor type 4 that is encoded in the genome of rat.


ABHGA_HUMAN Phosphatidylserine lipase ABHD16A (sprot)

A phosphatidylserine lipase ABHD16A that is encoded in the genome of human.


ABD12_HUMAN Lysophosphatidylserine lipase ABHD12 (sprot)

A lysophosphatidylserine lipase ABHD12 that is encoded in the genome of human.


PAFA_HUMAN Platelet-activating factor acetylhydrolase (sprot)

A platelet-activating factor acetylhydrolase that is encoded in the genome of human.


MGLL_MOUSE Monoglyceride lipase (sprot)

A monoglyceride lipase that is encoded in the genome of mouse.


FAAH1_MOUSE Fatty-acid amide hydrolase 1 (sprot)

A fatty-acid amide hydrolase 1 that is encoded in the genome of mouse.


STK3_HUMAN Serine/threonine-protein kinase 3 (sprot)

A serine/threonine-protein kinase 3 that is encoded in the genome of human.


KS6A6_HUMAN Ribosomal protein S6 kinase alpha-6 (sprot)

A ribosomal protein S6 kinase alpha-6 that is encoded in the genome of human.


NUAK2_HUMAN NUAK family SNF1-like kinase 2 (sprot)

A NUAK family SNF1-like kinase 2 that is encoded in the genome of human.


P96878_MYCTU carbonic anhydrase (trembl)


SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (sprot)

A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of chicken.


GBRA5_RAT Gamma-aminobutyric acid receptor subunit alpha-5 (sprot)

A gamma-aminobutyric acid receptor subunit alpha-5 that is encoded in the genome of rat.


HDAH_ALCSD Histone deacetylase-like amidohydrolase (sprot)


C3SWJ7_ECOLX Thymidylate synthase (trembl)


HRH3_MOUSE Histamine H3 receptor (sprot)

A histamine H3 receptor that is encoded in the genome of mouse.


CXCR1_HUMAN C-X-C chemokine receptor type 1 (sprot)

A C-X-C chemokine receptor type 1 that is encoded in the genome of human.


VATB2_HUMAN V-type proton ATPase subunit B, brain isoform (sprot)

A V-type proton ATPase subunit B, brain isoform that is encoded in the genome of human.


PAK3_HUMAN Serine/threonine-protein kinase PAK 3 (sprot)

A serine/threonine-protein kinase PAK 3 that is encoded in the genome of human.


CDK17_HUMAN Cyclin-dependent kinase 17 (sprot)

A cyclin-dependent kinase 17 that is encoded in the genome of human.


CDK14_HUMAN Cyclin-dependent kinase 14 (sprot)

A cyclin-dependent kinase 14 that is encoded in the genome of human.


MYLK4_HUMAN Myosin light chain kinase family member 4 (sprot)

A myosin light chain kinase family member 4 that is encoded in the genome of human.


WEE1_HUMAN Wee1-like protein kinase (sprot)

A Wee1-like protein kinase that is encoded in the genome of human.


M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 (sprot)

A mitogen-activated protein kinase kinase kinase 20 that is encoded in the genome of human.


KC1AL_HUMAN Casein kinase I isoform alpha-like (sprot)

A casein kinase I isoform alpha-like that is encoded in the genome of human.


KC1D_HUMAN Casein kinase I isoform delta (sprot)

A casein kinase I isoform delta that is encoded in the genome of human.


TLK1_HUMAN Serine/threonine-protein kinase tousled-like 1 (sprot)

A serine/threonine-protein kinase tousled-like 1 that is encoded in the genome of human.


TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 (sprot)

A serine/threonine-protein kinase tousled-like 2 that is encoded in the genome of human.


NTRK3_HUMAN NT-3 growth factor receptor (sprot)

An NT-3 growth factor receptor that is encoded in the genome of human.


TXK_HUMAN Tyrosine-protein kinase TXK (sprot)

A tyrosine-protein kinase TXK that is encoded in the genome of human.


CSK22_HUMAN Casein kinase II subunit alpha' (sprot)

A casein kinase II subunit alpha' that is encoded in the genome of human.


DYR1B_HUMAN Dual specificity tyrosine-phosphorylation-regulated kinase 1B (sprot)

A dual specificity tyrosine-phosphorylation-regulated kinase 1B that is encoded in the genome of human.


IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon (sprot)

An inhibitor of nuclear factor kappa-B kinase subunit epsilon that is encoded in the genome of human.


LIMK2_HUMAN LIM domain kinase 2 (sprot)

A LIM domain kinase 2 that is encoded in the genome of human.


STK26_HUMAN Serine/threonine-protein kinase 26 (sprot)

A serine/threonine-protein kinase 26 that is encoded in the genome of human.


INSRR_HUMAN Insulin receptor-related protein (sprot)

An insulin receptor-related protein that is encoded in the genome of human.


RIOK3_HUMAN Serine/threonine-protein kinase RIO3 (sprot)

A serine/threonine-protein kinase RIO3 that is encoded in the genome of human.


SIK2_HUMAN Serine/threonine-protein kinase SIK2 (sprot)

A serine/threonine-protein kinase SIK2 that is encoded in the genome of human.


SRPK2_HUMAN SRSF protein kinase 2 (sprot)

An SRSF protein kinase 2 that is encoded in the genome of human.


AVR2B_HUMAN Activin receptor type-2B (sprot)

An activin receptor type-2B that is encoded in the genome of human.


DDR2_HUMAN Discoidin domain-containing receptor 2 (sprot)

A discoidin domain-containing receptor 2 that is encoded in the genome of human.


COQ8A_HUMAN Atypical kinase COQ8A, mitochondrial (sprot)

An atypical kinase COQ8A, mitochondrial that is encoded in the genome of human.


LATS2_HUMAN Serine/threonine-protein kinase LATS2 (sprot)

A serine/threonine-protein kinase LATS2 that is encoded in the genome of human.


M4K1_HUMAN Mitogen-activated protein kinase kinase kinase kinase 1 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 1 that is encoded in the genome of human.


PAK6_HUMAN Serine/threonine-protein kinase PAK 6 (sprot)

A serine/threonine-protein kinase PAK 6 that is encoded in the genome of human.


NUAK1_HUMAN NUAK family SNF1-like kinase 1 (sprot)

A NUAK family SNF1-like kinase 1 that is encoded in the genome of human.


M4K3_HUMAN Mitogen-activated protein kinase kinase kinase kinase 3 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 3 that is encoded in the genome of human.


BLK_HUMAN Tyrosine-protein kinase Blk (sprot)

A tyrosine-protein kinase BLK that is encoded in the genome of human.


M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 (sprot)

A mitogen-activated protein kinase kinase kinase kinase 4 that is encoded in the genome of human.


MARK1_HUMAN Serine/threonine-protein kinase MARK1 (sprot)

A serine/threonine-protein kinase MARK1 that is encoded in the genome of human.


MARK4_HUMAN MAP/microtubule affinity-regulating kinase 4 (sprot)

A MAP/microtubule affinity-regulating kinase 4 that is encoded in the genome of human.


MP2K6_HUMAN Dual specificity mitogen-activated protein kinase kinase 6 (sprot)

A dual specificity mitogen-activated protein kinase kinase 6 that is encoded in the genome of human.


MERTK_HUMAN Tyrosine-protein kinase Mer (sprot)

A tyrosine-protein kinase Mer that is encoded in the genome of human.


CD11B_HUMAN Cyclin-dependent kinase 11B (sprot)

A cyclin-dependent kinase 11B that is encoded in the genome of human.


CDK19_HUMAN Cyclin-dependent kinase 19 (sprot)

A cyclin-dependent kinase 19 that is encoded in the genome of human.


M3K9_HUMAN Mitogen-activated protein kinase kinase kinase 9 (sprot)

A mitogen-activated protein kinase kinase kinase 9 that is encoded in the genome of human.


M3K10_HUMAN Mitogen-activated protein kinase kinase kinase 10 (sprot)

A mitogen-activated protein kinase kinase kinase 10 that is encoded in the genome of human.


M3K11_HUMAN Mitogen-activated protein kinase kinase kinase 11 (sprot)

A mitogen-activated protein kinase kinase kinase 11 that is encoded in the genome of human.


MRCKA_HUMAN Serine/threonine-protein kinase MRCK alpha (sprot)

A serine/threonine-protein kinase MRCK alpha that is encoded in the genome of human.


MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta (sprot)

A serine/threonine-protein kinase MRCK beta that is encoded in the genome of human.


STK24_HUMAN Serine/threonine-protein kinase 24 (sprot)

A serine/threonine-protein kinase 24 that is encoded in the genome of human.


MUSK_HUMAN Muscle, skeletal receptor tyrosine-protein kinase (sprot)

A muscle, skeletal receptor tyrosine-protein kinase that is encoded in the genome of human.


KC1G1_HUMAN Casein kinase I isoform gamma-1 (sprot)

A casein kinase I isoform gamma-1 that is encoded in the genome of human.


DAPK1_HUMAN Death-associated protein kinase 1 (sprot)

A death-associated protein kinase 1 that is encoded in the genome of human.


DCLK1_HUMAN Serine/threonine-protein kinase DCLK1 (sprot)

A serine/threonine-protein kinase DCLK1 that is encoded in the genome of human.


DCLK2_HUMAN Serine/threonine-protein kinase DCLK2 (sprot)

A serine/threonine-protein kinase DCLK2 that is encoded in the genome of human.


PAK4_HUMAN Serine/threonine-protein kinase PAK 4 (sprot)

A serine/threonine-protein kinase PAK 4 that is encoded in the genome of human.


BRSK2_HUMAN Serine/threonine-protein kinase BRSK2 (sprot)

A serine/threonine-protein kinase BRSK2 that is encoded in the genome of human.


CDK3_HUMAN Cyclin-dependent kinase 3 (sprot)

A cyclin-dependent kinase 3 that is encoded in the genome of human.


SIK1_HUMAN Serine/threonine-protein kinase SIK1 (sprot)

A serine/threonine-protein kinase SIK1 that is encoded in the genome of human.


SRMS_HUMAN Tyrosine-protein kinase Srms (sprot)

A tyrosine-protein kinase Srms that is encoded in the genome of human.


TESK1_HUMAN Dual specificity testis-specific protein kinase 1 (sprot)

A dual specificity testis-specific protein kinase 1 that is encoded in the genome of human.


TGFR1_HUMAN TGF-beta receptor type-1 (sprot)

A TGF-beta receptor type-1 that is encoded in the genome of human.


PLK3_HUMAN Serine/threonine-protein kinase PLK3 (sprot)

A serine/threonine-protein kinase PLK3 that is encoded in the genome of human.


EPHB3_HUMAN Ephrin type-B receptor 3 (sprot)

An ephrin type-B receptor 3 that is encoded in the genome of human.


MK06_HUMAN Mitogen-activated protein kinase 6 (sprot)

A mitogen-activated protein kinase 6 that is encoded in the genome of human.


MK07_HUMAN Mitogen-activated protein kinase 7 (sprot)

A mitogen-activated protein kinase 7 that is encoded in the genome of human.


KPCD2_HUMAN Serine/threonine-protein kinase D2 (sprot)

A serine/threonine-protein kinase D2 that is encoded in the genome of human.


RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 (sprot)

A receptor-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human.


FKB1B_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP1B (sprot)

A peptidyl-prolyl cis-trans isomerase FKBP1B that is encoded in the genome of human.


KS6A1_HUMAN Ribosomal protein S6 kinase alpha-1 (sprot)

A ribosomal protein S6 kinase alpha-1 that is encoded in the genome of human.


KS6A4_HUMAN Ribosomal protein S6 kinase alpha-4 (sprot)

A ribosomal protein S6 kinase alpha-4 that is encoded in the genome of human.


MGLL_HUMAN Monoglyceride lipase (sprot)

A monoglyceride lipase that is encoded in the genome of human.


GBA2_HUMAN Non-lysosomal glucosylceramidase (sprot)

A non-lysosomal glucosylceramidase that is encoded in the genome of human.


Q8VH26_CAVPO Muscarinic acetylcholine receptor (trembl)


Q81VW8_BACAN Dihydropteroate synthase (trembl)


XDH_RAT Xanthine dehydrogenase/oxidase (sprot)

A xanthine dehydrogenase/oxidase that is encoded in the genome of rat.


Q7X1P7_STREE DNA topoisomerase (ATP-hydrolyzing) (Fragment) (trembl)


DHI2_RAT 11-beta-hydroxysteroid dehydrogenase type 2 (sprot)

An 11-beta-hydroxysteroid dehydrogenase type 2 that is encoded in the genome of rat.


SUIS_HUMAN Sucrase-isomaltase, intestinal (sprot)

A sucrase-isomaltase, intestinal that is encoded in the genome of human.


VDR_PIG Vitamin D3 receptor (sprot)

A vitamin D3 receptor that is encoded in the genome of pig.


ABL1_MOUSE Tyrosine-protein kinase ABL1 (sprot)

A tyrosine-protein kinase ABL1 that is encoded in the genome of mouse.


PK3CB_HUMAN Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (sprot)

A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform that is encoded in the genome of human.


KC1A_HUMAN Casein kinase I isoform alpha (sprot)

A casein kinase I isoform alpha that is encoded in the genome of human.


MINK1_HUMAN Misshapen-like kinase 1 (sprot)

A misshapen-like kinase 1 that is encoded in the genome of human.


TBK1_HUMAN Serine/threonine-protein kinase TBK1 (sprot)

A serine/threonine-protein kinase TBK1 that is encoded in the genome of human.


IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 (sprot)

An interleukin-1 receptor-associated kinase 4 that is encoded in the genome of human.


CDK4_HUMAN Cyclin-dependent kinase 4 (sprot)

A cell division protein kinase 4 that is encoded in the genome of human.


CHK2_HUMAN Serine/threonine-protein kinase Chk2 (sprot)

A serine/threonine-protein kinase Chk2 that is encoded in the genome of human.


DLK1_HUMAN Protein delta homolog 1 (sprot)

A protein delta homolog 1 that is encoded in the genome of human.


EPHB6_HUMAN Ephrin type-B receptor 6 (sprot)

An ephrin type-B receptor 6 that is encoded in the genome of human.