suppression by virus of host natural killer cell activation

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host.


posterior compartment specification

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.


clathrin-mediated membrane bending

A membrane bending process mediated by clathrin.


biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.


hydroxymethylfurfural reductase (NADH) activity

Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.


regulation of defecation rhythm

Any process that modulates the frequency, rate or extent of defecation rhythm.


protein localization to phagocytic vesicle

A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle.


non-phosphorylated glucose metabolic process

The chemical reactions and pathways involving non-phosphorylated forms of glucose.


nitrobenzene nitroreductase activity

Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O.


inositol 3-kinase activity

Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.


thienylcyclohexylpiperidine binding

Binding to thienylcyclohexylpiperidine.


negative regulation of distal tip cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration.


24-epi-campsterol desaturase activity

Catalysis of the reaction: 24-epi-campesterol + NADPH + H+ + O2 <=> brassicasterol + NADP + 2 H2O.


Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O.


beta-carotene isomerase activity

Catalyzes the reaction: all-trans-beta-carotene = 9-cis-beta-carotene.


Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.


penetration peg formation

The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.


heparan sulfate 2-O-sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.


trypanothione-disulfide reductase (NADP) activity

Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.


maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded

Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster.


gamma-linolenate elongase activity

Catalysis of the reaction: malonyl-CoA + gamma-linolenoyl-CoA + H+ = (8Z,11Z,14Z)-3-oxoicosa-8,11,14-trienoyl-CoA + coenzyme A + carbon dioxide.


negative regulation of compound eye retinal cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.


(+)-kotanin catabolic process

The chemical reactions and pathways resulting in the breakdown of (+)-kotanin.


FAD transmembrane transporter activity

Enables the directed movement of flavin-adenine dinucleotide (FAD) from one side of a membrane to the other. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.


alcohol O-cinnamoyltransferase activity

Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate.


voltage-gated sodium channel activity involved in AV node cell action potential

Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


wall teichoic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.


trisporic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of trisporic acid.


abscisic aldehyde oxidase activity

Catalysis of the reaction: (+)-abscisic aldehyde + H2O + O2 = abscisate + H2O2 + H+.


nicotinic acid receptor activity

Combining with nicotinic acid to initiate a change in cell activity.


choline O-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.


kaempferol 3-sophoroside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP-L-rhamnose <=> kaempferol 3-O-rhamnosyl(1->2)glucoside-7-O-rhamnoside + UDP.


GA5 2,3 epoxidase activity

Catalysis of the reaction: gibberellin A5 + O2 + 2-oxoglutarate <=> gibberellin A6 + succinate + carbon dioxide.


sepiapterin deaminase activity

Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3.


2-methylisocitrate dehydratase activity

Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H2O.


positive regulation of wax biosynthetic process

Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.


Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.


detection of brassinosteroid stimulus

The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal.


positive regulation of neutrophil mediated cytotoxicity

Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.


naphthalene catabolic process

The chemical reactions and pathways resulting in the breakdown of naphthalene.


dimethylsilanediol hydroxylase activity

Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.


renal potassium excretion

The elimination of potassium ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.


3'-tRNA processing endoribonuclease activity

Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.


C-terminal protein demethylation

The removal of a methyl group from the C-terminal amino acid of a protein.


homoglutathione synthase activity

Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H+ + phosphate.


thalianol metabolic process

The chemical reactions and pathways involving the triterpene thalianol.


exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.


catalytic activity, acting on a glycoprotein

Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein.


L-glycol dehydrogenase activity

Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.


Catalysis of the reaction: indol-3-ylmethylamine + S-adenosyl-L-methionine = H+ + N-methyl-3-aminomethylindole + S-adenosyl-L-homocysteine.


snRNA localization to Cajal body

The directed movement of snRNA, small nuclear ribonucleic acid, to a Cajal body.


L-arabinose catabolic process to xylulose 5-phosphate

The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate.


mitochondrial tRNA wobble position uridine thiolation

The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.


jasmonyl-Ile conjugate hydrolase activity

Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.


coniferin beta-glucosidase activity

Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.


L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)

Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O.


dorsal closure, amnioserosa morphology change

The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.


negative regulation of anther dehiscence

Any process that stops, prevents, or reduces the frequency, rate or extent of anther dehiscence.


pollen tube guidance

The process in which the growth of pollen tube is directed towards the female gametophyte.


perturbation of host T-cell mediated immune response

A process in which an organism effects a change that affects the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H+ + phosphate.


rRNA (cytosine) methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.


collagen and cuticulin-based cuticle attachment to epithelium

Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.


negative regulation of entry of bacterium into host cell

Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.


medial fin morphogenesis

The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.


vitelline membrane formation involved in chorion-containing eggshell formation

Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.


lutein oxygenase activity

Catalysis of the reaction: lutein + 2 O2 = 3-hydroxy-beta-ionone + 3-hydroxy-alpha-ionone + 4,9-dimethyldodeca-2,4,6,8,10-pentaenedial.


Gram-negative-bacterium-type cell outer membrane assembly

The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.


phenolic phthiocerol biosynthetic process

The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.


invagination involved in gastrulation with mouth forming second

The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation.


establishment of secretory granule localization

The directed movement of a secretory granule to a specific location.


symbiont-mediated suppression of host cAMP-mediated signal transduction

A process in which a virus interferes with, inhibits or disrupts a cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of iridophore differentiation

Any process that modulates the frequency, rate or extent of iridophore differentiation.


regulation of intracellular signal transduction

Any process that modulates the frequency, rate or extent of intracellular signal transduction.


spermine transmembrane transporter activity

Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.


CGU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CGU codon.


L-isoleucine biosynthetic process

The chemical reactions and pathways resulting in the formation of L-isoleucine.


hydroxy-nicotine oxidase activity

Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.


MHC class I protein complex assembly

The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.


negative regulation of pro-T cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.


epithelial cell fate determination, open tracheal system

The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster.


intermediate mesodermal cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.


regulation of cyanophore differentiation

Any process that modulates the frequency, rate or extent of cyanophore differentiation.


Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.


negative regulation of egg-laying behavior

Any process that stops, prevents or reduces the frequency, rate or extent of oviposition.


anterior compartment pattern formation

The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.


ATPase-coupled phosphate ion transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).


creatinine catabolic process

The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.


negative regulation of vascular associated smooth muscle cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.


replacement bone morphogenesis

The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone.


S phase

The cell cycle phase, following G1, during which DNA synthesis takes place.


post-embryonic hindgut morphogenesis

The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.


The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.


negative regulation of chromosome separation

Any process that stops, prevents or reduces the frequency, rate or extent of chromosome separation.


peptidyl-threonine palmitoylation

The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.


cell wall (1->3)-beta-D-glucan metabolic process

The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.


negative regulation of response to salt stress

Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.


Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H+ + UDP.


nucleotide-sulfate transmembrane transporter activity

Enables the transfer of nucleotide-sulfate from one side of a membrane to the other.


kaempferol 3-gentiobioside 7-O-rhamnosyltransferase activity

Catalysis of the reaction: kaempferol-3-gentiobioside + UDP-L-rhamnose = H+ + kaempferol-3-O-gentiobioside-7-O-rhamnoside + UDP.


regulation of ureter smooth muscle cell differentiation

Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.


Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.


detoxification of free heme

Any process that reduces or removes the toxicity of free heme. These include transport of heme away from sensitive areas and to compartments or complexes whose purpose is sequestration of heme.


spermine oxidase (propane-1,3-diamine-forming) activity

Catalysis of the reaction: H2O + O2 + spermine = 1,3-diaminopropane + H2O2 + N-(3-aminopropyl)-4-aminobutanal.


fimbrial usher porin activity

A porin that acts in the assembly of fimbria together with fimbrial chaperone.


palmitoyl-CoA ligase activity

Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.


isopenicillin-N synthase activity

Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 = 2 H2O + isopenicillin N.


cellular response to carbon dioxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.


Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.


lysyl-tRNA aminoacylation

The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. The lysyl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a lysine-accetping tRNA.


phenylethylamine biosynthetic process

The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.


Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H+ + UDP.


manganese peroxidase activity

Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O.


positive regulation of development, heterochronic

Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached.


flight behavior

The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.


response to farnesol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.


Catalysis of the reaction: (11Z)-eicosenoyl-CoA + NADH + O2 + H+ = lesqueroloyl-CoA + NAD + H2O.


innate vocalization behavior

A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.


2-enoate reductase activity

Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.


negative regulation of hemocyte differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.


ferredoxin-NAD(P) reductase activity

Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.


Catalysis of the reaction: L-glutamyl-[protein] + NAD+ = 5-O-(ADP-D-ribosyl)-L-glutamyl-[protein] + nicotinamide.


negative regulation of shoot apical meristem development

Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development.


toluene-containing compound metabolic process

The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.


positive regulation of mesodermal cell differentiation

Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.


Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.


ecdysone oxidase activity

Catalysis of the reaction: Ecdysone + O2 = 3-dehydroecdysone + H2O2.


sucrose transmembrane transporter activity

Enables the transfer of sucrose from one side of a membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.


cellular response to GW 7647

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.


stachyose galactinol:verbascose galactosyltransferase activity

Catalysis of the reaction: stachyose + alpha-D-galactosyl-(1->3)-1D-myo-inositol <=> verbascose + myo-inositol.


regulation of G-protein activated inward rectifier potassium channel activity

Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.


cellular response to gastrin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.


Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).


arsenate reductase activity

Catalysis of the interconversion of arsenate and arsenite.


tryptophan catabolic process to catechol

The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol.


methylselenol reductase activity

Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O.


dorsal cochlear nucleus development

The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.


alpha-pinene monooxygenase [NADH] activity

Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.


leg disc proximal/distal pattern formation

The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.


visceral mesoderm-endoderm interaction involved in midgut development

The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.


proteolysis within endosome associated with antigen processing and presentation

The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.


intracellular sulfate ion homeostasis

A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell.


N-carbamoylputrescine amidase activity

Catalysis of the reaction: N-carbamoylputrescine + H2O + 2 H+ = CO2 + NH4 + putrescine.


post-embryonic ectodermal digestive tract development

The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.


photosynthetic electron transport chain

A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.


Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.


cellular response to histidine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.


positive regulation of leukotriene production involved in inflammatory response

Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.


envenomation resulting in hemorrhagic damage in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.


Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.


arsenate reductase (donor) activity

Catalysis of the reaction: A + arsenite + H2O = AH(2) + arsenate + 2 H+.


xanthophyll biosynthetic process

The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.


Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate.


aerobic respiration, using ammonia as electron donor

The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.


phenylalanine ammonia-lyase activity

Catalysis of the reaction: L-phenylalanine = NH4 + trans-cinnamate.


sesquiterpene metabolic process

The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.


complement component C3d receptor activity

Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


muscle thin filament assembly

The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.


cellular response to fluoride

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.


Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.


negative regulation of basidiospore formation

Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.


Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP.


B cell chemotaxis across high endothelial venule

The movement of a B cell to cross a high endothelial venule in response to an external stimulus.


Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H+ + luciferyl sulfate.


chloroplast RNA processing

The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.


ecdysteroid 22-hydroxylase activity

Catalysis of the hydroxylation of an ecdysteroid at carbon position 22.


glutamic-type peptidase activity

Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.


negative regulation of thymine transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus

Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.


hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.


glutamine catabolic process to fumarate

The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate.


lipoic acid binding

Binding to lipoic acid, 1,2-dithiolane-3-pentanoic acid.


lycopene metabolic process

The chemical reactions and pathways involving lycopene.


Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.


3-oxoadipyl-CoA thiolase activity

Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.


Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.


apiogalacturonan metabolic process

The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.


Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.


monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity

Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.


regulation of FtsZ-dependent cytokinesis

Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis.


Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H+.


lateral mesodermal cell fate commitment

The process in which a cell becomes committed to become a lateral mesoderm cell.


Catalysis of the reaction: [thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O.


Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.


poly(beta-D-mannuronate) lyase activity

Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.


Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).


positive regulation of exit from meiosis

Any process that activates or increases the frequency, rate or extent of exit from meiosis.


structural constituent of cutaneous appendage

The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.


aerobic phenol-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.


specification of metanephric proximal tubule identity

The process in which the proximal tubule of the metanephric nephron acquires its identity.


S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity

Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine.


abscisic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.


circadian sleep/wake cycle, wakefulness

The part of the circadian sleep/wake cycle where the organism is not asleep.


protein localization to prospore membrane

A process in which a protein is transported to, or maintained in, a location within a prospore membrane.


limb spinous cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


cyanoamino acid metabolic process

The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group.


beta-N-acetylglucosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.


regulation of pharynx morphogenesis

Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized.


basal dendrite morphogenesis

The process in which the anatomical structures of a basal dendrite are generated and organized.


cellular response to selenium ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.


contact chemoreceptor activity

A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.


Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.


regulation of cell adhesion involved in sprouting angiogenesis

Any process that modulates the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.


regulation of imaginal disc-derived leg joint morphogenesis

Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized.


intracellular cAMP-activated cation channel activity involved in regulation of postsynaptic membrane potential

Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts, to regulate the postsynaptic membrane potential.


response to polyamine macromolecule

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.


Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.


CENP-A containing nucleosome binding

Binding to a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).


cellular response to serotonin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.


negative regulation of cellular response to heat

Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat.


Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+.


citrate-L-glutamate ligase activity

Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.


transmembrane histidine kinase cytokinin receptor activity

Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.


maintenance of protein location in cell cortex of cell tip

A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.


regulation of backward locomotion

Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.


myo-inositol transmembrane transporter activity

Enables the transfer of myo-inositol from one side of a membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.


molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide

The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide.


bacteriochlorophyll metabolic process

The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.


(R)-2-methylmalate dehydratase activity

Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H2O.


arogenate dehydrogenase (NADP+) activity

Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.


Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP + H+ = diphosphate + GDP-beta-L-fucose.


picolinic acid metabolic process

The chemical reactions and pathways involving picolinic acid.


negative regulation of secondary cell wall biogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.


polyphosphate-mediated signaling

Any process that mediates the transfer of information from one cell to another using polyphosphate as the signal.


alcohol dehydrogenase [NAD(P)+] activity

Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.


glycerol dehydrogenase [NADP+] activity

Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.


proboscis morphogenesis

The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.


negative regulation of lateral motor column neuron migration

Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration.


4-toluenecarboxylate metabolic process

The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.


xylulokinase activity

Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H+.


Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.


T cell tolerance induction to tumor cell

A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.


cyanidin 3,7-diglucoside glucosidase activity

Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose.


subpallium glioblast cell division

The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes.


reproductive fruiting body development

The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.


glutamate catabolic process to oxaloacetate

The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate.


mannose-1-phosphate guanylyltransferase (GTP) activity

Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose.


cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.


CDP-diacylglycerol catabolic process

The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.


acyl-CoA binding

Binding to an acyl-CoA, a thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid.


Catalysis of the reaction: 5-(pentadeca-8,11,14-trien-1-yl)resorcinol + S-adenosyl-L-methionine <=> H+ + 5-(pentadeca-8,11,14-trien-1-yl)resorcinol monomethyl ether + S-adenosyl-L-homocysteine.


transitional two stage B cell differentiation

The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.


cell wall polysaccharide catabolic process

The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides.


Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.


RNA trimethylguanosine synthase activity

Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.


aldehyde dehydrogenase (FAD-independent) activity

Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor.


teliospore formation

The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.


establishment of pole plasm mRNA localization

Any process that results in the directed movement of mRNA to the oocyte pole plasm.


leukotriene D4 catabolic process

The chemical reactions and pathways resulting in the breakdown of leukotriene D4.


negative regulation of cell chemotaxis to fibroblast growth factor

Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.


adult chitin-based cuticle development

Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster.


Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.


positive regulation of Schwann cell chemotaxis

Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.


cell motility in response to calcium ion

Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.


malyl-CoA lyase activity

Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.


light-activated voltage-gated calcium channel activity

Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.


regulation of microglia differentiation

Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.


carbohydrate derivative binding

Binding to a carbohydrate derivative.


interferon-tau production

The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


early neuron fate commitment in forebrain

The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.


D-amino acid transmembrane transporter activity

Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.


active borate transmembrane transporter activity

Enables the transport of borate across a membrane against the concentration gradient.


ERBB3 signaling pathway

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission.


photosystem II repair

Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.


Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+.


positive regulation of pyloric antrum smooth muscle contraction

Any process that increases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


pyrrolysyl-tRNA synthetase activity

Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl).


nucleus-vacuole junction assembly

The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction (NVJ), membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p. The NVJ plays roles in piecemeal microautophagy of the nucleus and in the cytoplasm-to-vacuole targeting pathway.


17-beta-ketosteroid reductase activity

Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.


cell wall chitin biosynthetic process

The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.


protein malonylation

The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.


positive regulation of plasmatocyte differentiation

Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.


vacuolar calcium ion homeostasis

Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.


GTP diphosphatase activity

Catalysis of the reaction: GTP + H2O = GMP + H+ + diphosphate.


imaginal disc-derived genitalia development

The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.


cardioblast cell fate determination

The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


dehydrogluconate dehydrogenase activity

Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).


host interaction involved in quorum sensing

A quorum sensing process that is modulated by some interaction with a host cell or organism.


Catalysis of the reaction: gluconapin + a reduced electron acceptor + O2 = xi-progoitrin + an oxidized electron acceptor + H2O.


positive regulation of defecation rhythm

Any process that activates or increases the frequency, rate or extent of defecation rhythm.


averantin hydroxylase activity

Catalyzes the reaction: (1'S)-averantin + [reduced NADPH--hemoprotein reductase] + O2 <=> (1'S,5'S)-5'-hydroxyaverantin + [oxidized NADPH--hemoprotein reductase] + H2O. Involved in aflatoxin biosynthesis.


purine deoxyribonucleoside biosynthetic process

The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).


anterior semicircular canal development

The progession of the anterior semicircular canal from its initial formation to the mature structure.


endocytosis, site selection

The process of selecting and or marking the position where endocytosis will occur.


mycothiol-dependent formaldehyde dehydrogenase activity

Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.


positive regulation of iodide transport

Any process that activates or increases the frequency, rate or extent of iodide transport.


regulation of developmental process

Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).


B cell anergy

Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.


axon regeneration at neuromuscular junction

The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.


regulation of short-term synaptic potentiation

Any process that modulates the frequency, rate or extent of short-term synaptic potentiation.


positive regulation of bile acid secretion

Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue.


low-density lipoprotein particle receptor catabolic process

The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.


Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.


genital disc pattern formation

The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.


ornithine cyclodeaminase activity

Catalysis of the reaction: L-ornithine = L-proline + NH4.


positive regulation of stomach fundus smooth muscle contraction

Any process that increases the frequency, rate or extent of any stomach fundus smooth muscle contraction.


dopaminergic neuron axon guidance

The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.


anaerobic nitrilotriacetate metabolic process

The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen.


mating-type alpha-factor pheromone receptor activity

Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity.


ketohexokinase activity

Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.


thiamine pyrophosphate transmembrane transporter activity

Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.


negative regulation of cellular defense response

Any process that stops, prevents, or reduces the rate of the cellular defense response.


pronephric duct development

The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.


estrogen 2-hydroxylase activity

Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O.


anandamide epoxidase activity

Catalysis of the epoxidation of double bonds of the arachidonoyl moiety of anandamide.


protein localization to microtubule end

A process in which a protein is transported to, or maintained in, a location at a microtubule end.


N-terminal protein formylation

The formylation of the N-terminal amino acid of proteins.


regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation

Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.


gibberellin transmembrane transporter activity

Enables the transfer of gibberellin from one side of a membrane to the other.


The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.


D-threonine aldolase activity

Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.


capsule poly-gamma-glutamate biosynthetic process

The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.


D-cysteine desulfhydrase activity

Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate.


negative regulation of gamma-delta T cell activation

Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation.


dorsal motor nucleus of vagus nerve development

The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.


C-C motif chemokine 21 receptor activity

Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


phosphoadenylylsulfatase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate.


cis-acting DNA replication termination

A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.


cellobiose dehydrogenase (acceptor) activity

Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.


lutein metabolic process

The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein.


positive regulation of retrograde axon cargo transport

Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.


Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity

Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.


Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP + 2 H+.


Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.


Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.


behavioral defense response to insect

A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.


snoRNA splicing

The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.


conversion of lysyl-tRNA to pyrrolysyl-tRNA

The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).


O-succinylbenzoate synthase activity

Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.


protein-heme linkage via 1'-L-histidine

The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine).


deoxyinosine metabolic process

The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside.


pantothenate transmembrane transporter activity

Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.


beta-primeverosidase activity

Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.


R7 cell development

The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.


natural killer cell differentiation involved in immune response

The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.


selenium-containing prosthetic group biosynthetic process

The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.


transmitting tissue development

The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.


cellular detoxification of fluoride

Any process carried out at the cellular level that reduces or removes the toxicity of a fluoride. These may include chemical modification or transport of fluoride away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


N-terminal protein amino acid carboxylation

The carboxylation of the N-terminal amino acid of proteins.


Wnt signaling pathway involved in animal/vegetal axis specification

The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.


GDP-mannose 6-dehydrogenase activity

Catalysis of the reaction: GDP-alpha-D-mannose + H2O + 2 NAD+ = GDP-D-mannuronate + 3 H+ + 2 NADH.


guaiacyl lignin biosynthetic process

The chemical reactions and pathways resulting in the formation of guaiacyl lignin.


lens fiber cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.


N',N'',N'''-triacetylfusarinine C biosynthetic process

The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C.


phenol metabolic process

The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group.


positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide

Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.


tube fusion

The joining of specific branches of a tubular system to form a continuous network.


2-iminoacetate synthase activity

Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+.


esculetin metabolic process

The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin.


pregnan-21-ol dehydrogenase (NADP+) activity

Catalysis of the reaction: NADP+ + pregnan-21-ol = H+ + NADPH + pregnan-21-al.


eye pigment catabolic process

The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.


enucleate erythrocyte maturation

A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.


T cell mediated cytotoxicity directed against tumor cell target

The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.


detection of chemical stimulus involved in magnetoreception

The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states.


The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed.


O-glycan processing, core 2

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.


interstitial cell of Cajal differentiation

The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.


Catalysis of the reaction: H+ + imidazol-4-ylacetate + NADH + O2 = 5-hydroxyimidazole-4-acetate + H2O + NAD+.


9-phenanthrol sulfotransferase activity

Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate.


anther development

The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.


regulation of hepatocyte apoptotic process

Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.


positive regulation by symbiont of host transcription

Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


actin filament bundle distribution

Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.


D-galactose 6-phosphate 1-epimerase activity

Catalysis of the reaction: alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate.


magnetoreception by sensory perception of electrical stimulus

The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.


protein localization to interphase microtubule organizing center

A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center.


perturbation by virus of host G0/G1 transition checkpoint

A process in which a virus interferes with the normal execution of the host cell G0/G1 transition checkpoint.


oxalate-CoA ligase activity

Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H+ + oxalyl-CoA.


histone H2B deubiquitinase activity

A histone deubiquitinase that cleaves ubiquitin from a histone H2B protein to which it is conjugated.


nicotinamide riboside biosynthetic process

The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.


clavulanic acid metabolic process

The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.


bud field specification

The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


bronchiole morphogenesis

The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.


Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative.


small intestine smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.


negative regulation of T cell costimulation

Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.


Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate.


protein localization to nuclear periphery

A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.


mesonephric glomerular mesangial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.


intronic box C/D RNA processing

Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.


Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H+ + UDP.


pancreatic E cell fate commitment

The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell.


ectodermal cell fate determination

The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.


antennal morphogenesis

The process in which the anatomical structures of the antenna are generated and organized.


Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.


positive regulation of toll-like receptor 12 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose 5-phosphate + H+ + NADPH.


sphingomyelin transfer activity

Removes a sphingomyelin from the outer leaflet of a donor membrane, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to the outer leaflet of an acceptor membrane.


cell competition in a multicellular organism

Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.


Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H+ + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate.


positive regulation of neural crest cell differentiation

Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation.


p-cresol metabolic process

The chemical reactions and pathways involving p-cresol.


Catalysis of the reduction of a peptide-linked thiazoline to thiazole.


kynurenine 7,8-hydroxylase activity

Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor.


TRAIL receptor activity

Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death.


positive regulation of plasma cell differentiation

Any process that activates or increases the frequency, rate or extent of plasma cell differentiation.


gibberellin A9 16alpha,17 epoxidase activity

Catalysis of the reaction: gibberellin A9 + O2 + H+ + NAD(P)H <=> 16alpha, 17-epoxy gibberellin A9 + H2O + NAD(P).


1-indanone monooxygenase activity

Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin.


histone H3K14 acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14).


propionate catabolic process

The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.


Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+.


Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative.


oxalate metabolic process

The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.


rhombomere 5 morphogenesis

The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.


chemotaxis to oxidizable substrate

The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose.


gliotoxin metabolic process

The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.


hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides

Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.


Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide.


streptomycin 3''-kinase activity

Catalysis of the reaction: ATP + streptomycin = ADP + 2 H+ + streptomycin 3''-phosphate.


B cell antigen processing and presentation following pinocytosis

B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.


regulation of protein catabolic process at synapse, modulating synaptic transmission

Any process that modulates synaptic transmission by regulating protein degradation at the synapse.


histone H3K79 methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group to the lysine residue at position 79 of the histone H3 protein.


The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.


regulation of chanoclavine-I aldehyde biosynthetic process

Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.


pyrithiamine deaminase activity

Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3.


diol catabolic process

The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.


negative regulation of prolactin signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.


positive regulation of toll-like receptor 10 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.


cellular response to selenite ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.


histone H3R2 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl (position 2)= histone H3 L-citrullyl (position 2) + NH4+, resulting in histone H3 citrullination at position 2.


ferric enterobactin:proton symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in).


maintenance of stationary phase in response to starvation

The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment.


regulation of metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.


N-acetylneuraminate lyase activity

Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.


respiratory basal cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell.


quercetin 2,3-dioxygenase activity

Catalysis of the reaction: H+ + O2 + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO.


dorsal spinal cord interneuron axon guidance

The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord.


phosphorus metabolic process

The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).


Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-).


D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity

Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+.


regulation of sensory perception of sweet taste

Any process that modulates the frequency, rate or extent of sensory perception of sweet taste.


astaxanthin biosynthetic process

The chemical reactions and pathways resulting in the formation of astaxanthin.


positive regulation of mini excitatory postsynaptic potential

Any process that increases the frequency, rate or extent of mini excitatory postsynaptic potential. Mini excitatory postsynaptic potential is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.


glucan 1,4-alpha-glucosidase activity

Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.


negative regulation of hypoxanthine transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


sulfate binding

Binding to sulfate, SO4(2-), a negatively charged small molecule.


high-affinity tryptophan transmembrane transporter activity

Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


adult foraging behavior

Behavior by which an adult locates food.


N-glycan processing to secreted and cell-surface N-glycans

The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.


Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.


somatic diversification of T cell receptor genes by N region addition

The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene.


Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP+ = 3-oxoglycyrrhetinate + H+ + NADPH.


(R,R)-butanediol dehydrogenase activity

Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H+.


cellular alkene metabolic process

The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells.


meiotic interphase II

The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge.


T cell meandering migration

The random-like motility observed for T cells in lymph nodes which enhances surveillance of antigens presented by major histocompatibility complex (MHC) molecules on antigen presenting cells (APCs).


The chemical reactions and pathways involving hercynylselenocysteine.


deoxyguanosine kinase activity

Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H+.


The chemical reactions and pathways resulting in the formation of lipooligosaccharide.


vomitoxin biosynthetic process

The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats.


positive regulation of neutrophil differentiation

Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.


riboflavin synthase activity

Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H+ = 5-amino-6-(D-ribitylamino)uracil + riboflavin.


hexuronate transmembrane transporter activity

Enables the transfer of hexuronates from one side of a membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.


positive regulation of mitotic cell cycle, embryonic

Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle.


cyanide hydratase activity

Catalysis of the reaction: formamide = H2O + hydrogen cyanide.


positive regulation of filamentous growth of a population of unicellular organisms in response to heat

Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.


interleukin-22 receptor activity

Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


regulation of establishment of cell polarity regulating cell shape

Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape.


Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.


Catalysis of the reaction: butein 4'-beta-D-glucoside + O2 = aureusidin 6-O-beta-glucoside + H2O + H+.


RNA cap 4 binding

Binding to a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa.


posterior neuropore closure

The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.


positive regulation of lymphoid progenitor cell differentiation

Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation.


methylnaphthalene catabolic process

The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.


ABC-type amino acid transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).


aurone metabolic process

The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.


tuberculosinol biosynthetic process

The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.


response to host pH environment

Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


regulation of artery morphogenesis

Any process that modulates the frequency, rate or extent of artery morphogenesis.


deoxyguanosine metabolic process

The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.


Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+.


acylagmatine amidase activity

Catalysis of the reaction: N(4)-benzoylagmatine + H2O = agmatine + benzoate.


peptidyl-alanine modification

The modification of peptidyl-alanine.


GUC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a GUC codon.


dGDP catabolic process

The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).


asparagine catabolic process via 2-oxosuccinamate

The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate.


positive regulation of developmental vegetative growth

Any process that activates or increases the frequency, rate or extent of developmental vegetative growth.


positive regulation of Frizzled Nuclear Import pathway

Any process that activates or increases the frequency, rate or extent of a Frizzled Nuclear Import pathway.


cell-cell adhesion involved in ameboidal cell migration

The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells.


helvolic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of helvolic acid.


modulation by symbiont of entry into host

Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.


negative regulation of response to propan-1-ol

Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol.


L-xylose 1-dehydrogenase activity

Catalysis of the reaction: aldehydo-L-xylose + NADP+ = L-xylono-1,4-lactone + H+ + NADPH.


podocyte apoptotic process

Any apoptotic process in a glomerular visceral epithelial cell.


cell wall organization

A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.


lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway

The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps.


arabinan transmembrane transporter activity

Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of a membrane to the other.


negative regulation of cell communication by chemical coupling

Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.


Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.


protein localization to cell-cell junction

A process in which a protein is transported to, or maintained, in a location within a cell-cell junction.


cytochrome-b5 reductase activity, acting on NADH

Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5).


male analia morphogenesis

The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc.


RNA 2'-O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + RNA = S-adenosyl-L-homocysteine + RNA containing 2'-O-methylribonucleotide.


regulation of hair cycle by canonical Wnt signaling pathway

The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle.


rDNA chromatin condensation

The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.


toluene-containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.


cyanophore differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.


far-red light photoreceptor activity

The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.


germ-line processes downstream of sex determination signal

The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways.


Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH.


box H/ACA RNA metabolic process

The chemical reactions and pathways involving box H/ACA type small nucleolar RNA.


acetate-CoA ligase (ADP-forming) activity

Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.


response to caloric restriction

A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake.


uridine transmembrane transporter activity

Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.


altruistic, chimeric sorocarp development

Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell.


chemotaxis to folate

The directed movement of a motile cell or organism in response to the presence of folate.


perturbation of host systemic acquired resistance

A process in which an organism effects a change that affects systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.


capsorubin catabolic process

The chemical reactions and pathways resulting in the breakdown of capsorubin.


instar larval or pupal development

The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster.


diglucosyl diacylglycerol synthase activity

Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol.


protein-DNA-RNA complex disassembly

The disaggregation of a protein-DNA-RNA complex into its constituent components.


anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light

The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus.


alkylbase DNA N-glycosylase activity

Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.


modulation of vasoactive intestinal polypeptide receptor activity in another organism

The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism.


Sertoli cell apoptotic process

Any apoptotic process in a Sertoli cell.


cell proliferation involved in heart valve development

Any cell proliferation that is involved in heart valve development.


response to tellurium ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.


glucose fermentation to lactate and acetate

The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP.


regulation of membrane depolarization during AV node cell action potential

Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential.


histone H3K36 dimethyltransferase activity

Catalysis of the reaction: L-lysyl36-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl36-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the lysine residue at position 36 of histone H3, producing histone H3K36me2.


UUG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UUG codon.


pyruvate oxidase activity

Catalysis of the reaction: H+ + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2.


Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H2O = LL-2,6-diaminopimelate + succinate.


negative regulation of interleukin-17-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway.


4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity

Catalysis of the reaction: 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NAD(P) = 4alpha-methyl-5alpha-cholesta-8-en-3-one + carbon dioxide + NAD(P)H.


positive regulation of lamellocyte differentiation

Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


positive regulation of zoospore encystment on host

Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.


oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.


Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate.


endoplasmic reticulum inheritance

The partitioning of endoplasmic reticulum between daughter cells at cell division.


Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.


chemokine (C-C motif) ligand 22 production

The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


positive regulation of response to macrophage colony-stimulating factor

Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor.


phosphomevalonate kinase activity

Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H+.


mesonephric intraglomerular mesangial cell proliferation

The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.


lipoyl(octanoyl) transferase activity

Catalysis of the reaction: L-lysyl-[protein] + octanoyl-[ACP] = H+ + holo-[ACP] + N6-octanoyl-L-lysyl-[protein].