response to butan-1-ol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus.


ursolic aldehyde 28-monooxygenase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O.


primary branching, open tracheal system

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster.


1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)

Catalysis of the reaction: a glucosylated glycogenin = a glycogen.


structural constituent of postsynaptic density

The action of a molecule that contributes to the structural integrity of a postsynaptic density.


cell proliferation involved in embryonic placenta development

The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.


negative regulation of germ cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation.


response to maltose

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.


dUTP biosynthetic process

The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate.


gynoecium development

The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.


Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine.


negative regulation of iodide transport

Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport.


swimming behavior

The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water.


mycotoxin biosynthetic process

The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.


glucagon-like peptide 1 receptor activity

Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein.


leukocyte activation-dependent arrest

The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.


Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O2 = 4-hydroxybenzoate + formate + 2 H+.


positive regulation of retrograde dense core granule transport

Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.


regulation of trehalose metabolic process

Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.


Catalysis of the reaction: 1-palmitoyl-2-linoleoyl-phosphatidylcholine + O2 + a reduced electron acceptor <=> 1-16:0-2-18:3-phosphatidylcholine + 2 H2O + an oxidized electron acceptor.


Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord

biolink:Pathway biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:OntologyClass biolink:Occurrent biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division.


stromal-epithelial cell signaling involved in prostate gland development

The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development.


P granule assembly

The aggregation, arrangement and bonding together of a set of components to form a P granule.


plastid inner membrane organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid.


negative regulation of collagen catabolic process

Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.


chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme

The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.


alginic acid catabolic process

The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).


prostaglandin-E2 9-reductase activity

Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.


9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene

The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene.


DNA (6-4) photolyase activity

Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA.


Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate.


uridine to cytidine editing

The conversion of a uridine residue to cytosine in an RNA molecule by amination.


L-threonine transmembrane transporter activity

Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.


copper incorporation into metallo-sulfur cluster

The incorporation of copper into a metallo-sulfur cluster.


anthranilate catabolic process

The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate).


trisaccharide binding

Binding to a trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.


protein trans-autophosphorylation

The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer.


cyclic nucleotide-gated mechanosensitive monoatomic ion channel activity

Enables the transmembrane transfer of an monoatomic ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.


dephospho-[reductase kinase] kinase activity

Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase].


GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine

The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


cardiac glial cell development

The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.


delta14-sterol reductase activity

Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.


Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.


cell wall (1->3)-alpha-glucan metabolic process

The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.


mesonephric S-shaped body morphogenesis

The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.


cytoplasmic actin-based contraction involved in rearward cell motility

The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.


selenoneine biosynthetic process

The chemical reactions and pathways resulting in the formation of selenoneine.


negative regulation of Schwann cell chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis.


prenol biosynthetic process

The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.


single-stranded 3'-5' DNA helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'.


negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone

Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.


mitotic cell cycle phase

One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.


light-independent bacteriochlorophyll biosynthetic process

The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.


formaldehyde assimilation via xylulose monophosphate cycle

The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds.


fatty acid alpha-hydroxylase activity

Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.


nephrocyte filtration

The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm.


lipopolysaccharide core heptosyltransferase activity

Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+.


double-strand break repair via transcription-associated homologous recombination

A mechanism of homologous recombination and DNA repair in which transcript RNA is used as a template for DSB repair.


metanephric capsule formation

The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.


pollen tube adhesion

The process in which the pollen tube adheres to cells of the stigma and style.


Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.


negative regulation of cardiocyte differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.


arteriole smooth muscle contraction

A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.


response to polycyclic arene

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.


Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O2 = CO2 + H2O + H+ + scopolamine + succinate.


Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans.


defecation

The expulsion of feces from the rectum.


menopause

Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50.


negative regulation of thyroid gland epithelial cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation.


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.


histone H2AK129 ubiquitin ligase activity

Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-129 residue.


bursa of Fabricius development

The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.


Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate.


soluble molecule recognition

The recognition of soluble molecules in the environment.


negative regulation of xanthophore differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.


cellular response to stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.


polyamine binding

Binding to a polyamine, an organic compound containing two or more amino groups.


chitin-based embryonic cuticle biosynthetic process

Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.


The series of molecular signals initiated by interleukin-17A binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


regulation of acetylcholine metabolic process

Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.


F-9775B metabolic process

The chemical reactions and pathways involving F-9775B.


viomycin kinase activity

Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).


glutarate-semialdehyde dehydrogenase (NADP+) activity

Catalysis of the reaction: 5-oxopentanoate + NADP + H2O = glutarate + NADPH + 2 H+.


triterpenoid catabolic process

The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units.


rhabdomere membrane biogenesis

A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane.


abducens nerve morphogenesis

The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


peptidyl-glutamine 2-methylation

The methylation of glutamine to form 2-methyl-L-glutamine.


protein N-linked glycosylation via arginine

The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine.


isopentenyl adenine biosynthetic process

The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.


hemaglutinin autotransporter activity

Enables the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively.


hexulose-6-phosphate synthase activity

Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate.


Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol.


UGA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UGA codon.


positive regulation of activin secretion

Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.


mitochondrial tRNA threonylcarbamoyladenosine modification

The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).


cellular stress response to acidic pH

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.


Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate.


positive regulation of pancreatic stellate cell proliferation

Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.


The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.


sex comb development

The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.


Enterobacter ribonuclease activity

Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.


regulation of planar cell polarity pathway involved in neural tube closure

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.


high-affinity secondary active ammonium transmembrane transporter activity

Enables the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


fucose biosynthetic process

The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose).


isoflavonoid biosynthetic process

The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.


tRNA C3-cytosine methylation

The process whereby a cytosine in a tRNA is methylated at position 3 of the cytosine.


Catalysis of the reaction: 17-O-acetylnorajmaline + NADP+ = 1,2-dihydrovomilenine + H+ + NADPH.


reverse transcription

A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis.


protein localization to medial cortex

A process in which a protein is transported to, or maintained in, the medial cortex.


protein serine kinase activity

Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.


Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate.


glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity

Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate.


endothelial cell fate determination

A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


meiotic anaphase II

The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.


trans-synaptic signaling by endocannabinoid, modulating synaptic transmission

Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.


prephenate dehydrogenase (NADP+) activity

Catalysis of the reaction: NADP+ + prephenate = (4-hydroxyphenyl)pyruvate + CO2 + NADPH.


head involution

Movement of the anterior ectoderm to the interior of the embryo.


mandelate catabolic process

The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.


regulation of oospore formation

Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.


sequestering of manganese ion

The process of binding or confining manganese ions such that they are separated from other components of a biological system.


positive regulation of intracellular lipid transport

Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.


parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.


spermidine deacetylation

The modification of acetylspermadine by the removal of acetyl groups.


single-species surface biofilm formation

A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.


butanediol biosynthetic process

The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.


cellular response to absence of light

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.


G/U mismatch-specific uracil-DNA glycosylase activity

Hydrolyzes mismatched double-stranded DNA and polynucleotides, releasing free uracil and leaving an apyrimidinic (AP) site.


D-myo-inositol (1,3,4,6)-tetrakisphosphate 2-kinase activity

Catalysis of the reaction: myo-inositol 1,3,4,6-tetrakisphosphate(8-) + ATP = H+ + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate(10-) + ADP.


oligoxyloglucan reducing-end-specific cellobiohydrolase activity

Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.


tagatose kinase activity

Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H+.


negative regulation of cystathionine beta-synthase activity

Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity.


negative regulation of skeletal muscle tissue growth

Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.


endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


pentalenolactone catabolic process

The chemical reactions and pathways resulting in the breakdown of pentalenolactone.


Catalysis of the reaction: cannabigerolate + O2 <=> delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide.


recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex

The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript.


response to lectin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.


regulation of T-helper 17 cell extravasation

Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation.


Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor.


dethiobiotin metabolic process

The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms.


membrane repolarization during AV node cell action potential

The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.


glucose-6-phosphate isomerase activity

Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.


Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde.


aureusidin synthase activity

Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.


neuronal action potential back-propagation

Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.


regulation of systemic arterial blood pressure by physical factors

The regulation of blood pressure mediated by detection of forces within the circulatory system.


sakuranetin 6-hydroxylase activity

Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP.


positive regulation of octopamine signaling pathway involved in response to food

Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food.


response to chloramphenicol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.


telomere-nuclear envelope anchor activity

The binding activity of a molecule that brings together the telomeric region of a chromosome and the inner nuclear membrane by interacting with both the telomere and the nuclear membrane, in order to establish and maintain the telomeric location.


replication fork reversal

Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.


calcium oxalate binding

Binding to calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).


interneuron axon guidance

The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.


dorsal convergence

The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.


excitation of vasomotor center by baroreceptor signaling

The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.


viral translational shunt

A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site.


response to cortisone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.


cellobiose glucosidase activity

Catalysis of the reaction: D-cellobiose + H2O = 2 D-glucose.


envenomation resulting in modulation of transmission of nerve impulse in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism.


regulation of neutrophil mediated killing of symbiont cell

Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.


negative regulation of sensory perception of bitter taste

Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste.


phenylacetaldoxime dehydratase activity

Catalysis of the reaction: (trans)-phenylacetaldoxime = H2O + phenylacetonitrile.


O-glycan processing, core 4

The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.


anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process

The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.


fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation

The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.


octopine catabolic process to proline

The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline.


Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H+.


regulation of cardiac muscle cell myoblast differentiation

Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.


creatinase activity

Catalysis of the reaction: creatine + H2O = sarcosine + urea.


choriogonadotropin hormone binding

Binding to choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit.


molybdenum cofactor guanylyltransferase activity

Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.


imaginal disc-derived wing hair elongation

Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.


beta-acoradiene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> beta-acoradiene + diphosphoric acid.


arabinose isomerase activity

Catalysis of the reaction: D-arabinose = D-ribulose.


NAD-dependent protein decrotonylase activity

Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[protein] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.


ectoine synthase activity

Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H2O.


tricaffeoyl spermidine O-methyltransferase activity

Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine.


trehalose O-mycolyltransferase activity

Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose.


acquisition of nutrients from host

The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.


maintenance of protein location in peroxisome

Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.


intronic snoRNA processing

The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.


negative regulation of ATP:ADP antiporter activity

Any process that stops or reduces the activity of an ATP:ADP antiporter.


non-phosphorylated glucose catabolic process

The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.


seed trichome differentiation

The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.


Catalysis of the reaction: beta-carotene + 2 NADH + 2 H+ + 2 O2 = (2R,2'R)-dihydroxy-all-trans-beta-carotene + 2 NAD + 2 H2O.


Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP+ = ethyl 3-oxohexanoate + H+ + NADPH.


positive regulation of lateral mesodermal cell fate determination

Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.


silicate transmembrane transporter activity

Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.


detection of muscle inactivity involved in regulation of muscle adaptation

The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.


aryl-alcohol dehydrogenase (NAD+) activity

Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.


Catalysis of the reaction: a phosphatidylcholine + a 1,2-diacyl-sn-glycerol = a 1,2-diacyl-sn-glycerol + a phosphatidylcholine.


glycyrrhetinate metabolic process

The chemical reactions and pathways involving glycyrrhetinate.


presynaptic actin cytoskeleton organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton.


positive regulation of natural killer cell tolerance induction

Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.


conidiogenone biosynthetic process

The chemical reactions and pathways resulting in the formation of conidiogenone , a diterpene known to induce the conidiation.


regulation of male pigmentation

Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.


regulation of galactoglucomannan catabolic process

Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.


D-aspartate ligase activity

Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+.


fatty acid primary amide catabolic process

The chemical reactions and pathways resulting in the breakdown of primary fatty amides.


histone dopaminyltransferase activity

Catalysis of the reaction: dopamine + L-glutaminyl-[histone] = 5-dopaminyl-L-glutamyl-[histone] + NH4(+).


regulation of toll-like receptor 11 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.


Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP.


ABC-type vitamin B12 transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: vitamin B12(out) + ATP + H2O = ADP + an vitamin B12(in) + H+ + phosphate. Vitamin B12 is alkylcob(III)alamin.


cyclopentanol dehydrogenase activity

Catalysis of the reaction: cyclopentanol + NAD+ = cyclopentanone + H+ + NADH.


peptidyl-cysteine modification to S-amindino-L-cysteine

The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.


Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.


NAD+- protein-cysteine ADP-ribosyltransferase activity

Catalysis of the reaction: L-cysteinyl-[protein] + NAD+ = H+ + nicotinamide + S-(ADP-D-ribosyl)-L-cysteinyl-[protein].


protein arginine kinase activity

Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.


benzo(a)pyrene 4,5-dioxygenase activity

Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol.


negative regulation of mitotic cytokinesis

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis.


UAA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UAA codon.


bulbus arteriosus development

The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.


histone H3Y41 kinase activity

Catalysis of the reaction: histone H3-tyrosine (position 41) + ATP = histone H3-phosphotyrosine (position 41) + ADP. This reaction is the addition of a phosphate group to the tyrosine residue at position 41 of histone H3.


positive regulation of thyroid hormone mediated signaling pathway

Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.


prostaglandin D2 11-ketoreductase activity

Catalysis of the reaction: prostaglandin D2 + H+ + NADPH = 11-epi-prostaglandin F2alpha + NADP+.


versicolorin B synthase activity

Catalysis of the reaction: versiconal = versicolorin B + H2O.


Catalysis of the reaction: malonyl-CoA + a palmitoyl-[acp] = 1-heptadecene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].


metal-dependent deNEDDylase activity

An metal-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.


dehydroaustinol biosynthetic process

The chemical reactions and pathways resulting in the formation of dehydroaustinol.


stretch-activated, monoatomic cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential

Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.


aldaric acid biosynthetic process

The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.


peripheral B cell selection

Any B cell selection process that occurs in the periphery.


dGMP salvage

Any process which produces a dGMP from derivatives of it, without de novo synthesis.


Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate.


pullulan catabolic process

The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.


positive regulation of cytokinesis, site selection

Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis.


formaldehyde dismutase activity

Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.


positive regulation of intracellular sterol transport

Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.


dorsal vessel aortic cell fate commitment

The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.


L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine

The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.


chloroplast fission

The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.


intracellular ornithine homeostasis

A homeostatic process involved in the maintenance of a steady state level of orthinine within a cell.


lactam catabolic process

The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.


CD80 biosynthetic process

The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.


Lewis x epitope biosynthetic process

The chemical reactions and pathways resulting in the formation of a Lewis x epitope, a trisaccharide (beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-beta-D-glucosamine) expressed on several glycolipids, glycoproteins, and proteoglycans of the nervous system. The related Lewis x epitope is formed by alpha(1,3) fucosylation of the N-acetylglucosaminyl residue of a type 2 histo-blood group antigen precursor disaccharide.


negative regulation of flocculation

Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.


positive regulation of cholangiocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.


regulation of double fertilization forming a zygote and endosperm

Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.


negative regulation of female pigmentation

Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.


lactate 2-monooxygenase activity

Catalysis of the reaction: (S)-lactate + O2 = acetate + CO2 + H2O.


cell wall modification involved in fruit ripening

The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.


hypoglossal nerve formation

The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.


coenzyme F420-1:gamma-L-glutamate ligase activity

Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate.


amylo-alpha-1,6-glucosidase activity

Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.


acryloyl-CoA reductase (NADH) activity

Catalysis of the reaction: propanoyl-CoA + NAD+ = acryloyl-CoA + H+ + NADH.


glycine dehydrogenase (cyanide-forming) activity

Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.


negative regulation of neuroblast migration

Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration.


phagosome-lysosome docking

The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere.


negative regulation of myeloid progenitor cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.


canthaxanthin 3-hydroxylase activity

Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O.


aldehyde oxygenase (deformylating) activity

Catalysis of the reaction a long-chain aldehyde + O2 + 2 NADPH = an alkane + formate + H2O + 2 NADP+.


chromate reductase activity

Catalysis of the reaction: chromate = chromium (III).


Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate.


L-methionine transmembrane transporter activity

Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.


islet amyloid polypeptide processing

The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).


aerobic glycerol catabolic process

The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen.


establishment of floral organ orientation

The process that determines the orientation of the floral organs with reference to the central axis of the flower.


regulation of GABA-A receptor activity

Any process that modulates the frequency, rate or extent of GABA-A receptor activity.


sodium-dependent organic anion transmembrane transporter activity

Enables the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner.


alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity

Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.


Catalysis of the reaction: D-ribose 5-phosphate + ADP + H+ = ADP-ribose + phosphate.


Catalysis of the reaction: dihydrochelirubine + H+ + NADPH + O2 = 12-hydroxydihydrochelirubine + H2O + NADP+.


cadinene catabolic process

The chemical reactions and pathways resulting in the breakdown of cadinene.


chemokine (C-C motif) ligand 6 production

The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


octanol catabolic process

The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH.


mesenchymal cell proliferation involved in prostate gland development

The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.


response to non-ionic osmotic stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.


regulation of floral organ abscission by signal transduction

The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.


regulation of catalase activity

Any process that modulates the frequency, rate or extent of catalase activity.


asperthecin biosynthetic process

The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.


cellular response to miconazole

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.


orotic acid metabolic process

The chemical reactions and pathways involving orotic acid.


fumarylpyruvate hydrolase activity

Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.


establishment of planar polarity involved in nephron morphogenesis

Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.


GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine

The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


D-lactate dehydrogenase (cytochrome c-553) activity

Catalysis of the reaction: (R)-lactate + 2 [Fe(III)cytochrome c553] = 2 [Fe(II)cytochrome c553] + 2 H+ + pyruvate.


plastid DNA replication

The process in which new strands of DNA are synthesized in a plastid.


positive regulation of chorionic trophoblast cell proliferation

Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.


L-lyxose metabolic process

The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.


de-etiolation

The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll.


protoporphyrinogen IX biosynthetic process from glycine

The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine.


mannogen catabolic process

The chemical reactions and pathways resulting in the breakdown of mannogen, a mannose-containing polysaccharide that is a major energy reserve in Leishmania.


lysosomal enzyme production involved in inflammatory response

The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels.


disruption of host phagocytosis

A process in which in a symbiont interferes with or inhibits host phagocytosis by targeting phagocytic signaling or the cellular phagocytic machinery. The host is defined as the larger of the organisms involved in a symbiotic interaction.


sperm aster formation

Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.


allose metabolic process

The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.


Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate.


terpenoid indole alkaloid biosynthetic process

The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).


GPI anchor release

The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane.


ubiquitin ligase complex scaffold activity

The binding activity of a molecule that brings together an ubiquitin ligase and an ubiquitin ligase-substrate adaptor, permitting those molecules to function in a coordinated way.


regulation of pattern recognition receptor signaling pathway

Any process that modulates the rate, frequency or extent of a pattern recognition receptor signaling pathway.


voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels

Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.


vesicle targeting, inter-Golgi cisterna

The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.


regulation of activated CD4-positive, alpha-beta T cell apoptotic process

Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.


lipoprotein biosynthetic process via N-acyl transfer

The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex.


protein localization to outer membrane

A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane.


Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O.


thiosulfate binding

Binding to a thiosulfate, a sulfur oxide that has formula O3S2.


phenol O-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H+.


cis-chlorobenzene dihydrodiol dehydrogenase activity

Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol.


positive regulation by virus of host cell division

Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division.


pentitol phosphate metabolic process

The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule.


tolerance induction in Peyer's patch

Tolerance induction taking place in the Peyer's patches.


cap-independent translational initiation of circular RNA

The process where translation initiation recruits the 40S ribosomal subunits in a cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate circRNA translation.


pancreas regeneration

The regrowth of a destroyed pancreas.


pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity

Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+.


positive regulation of neutrophil mediated killing of gram-positive bacterium

Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.


iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide

The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide.


apposition of dorsal and ventral imaginal disc-derived wing surfaces

The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.


D-arabitol catabolic process

The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.


larval wandering behavior

The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.


regulation of acinar cell proliferation

Any process that modulates the frequency, rate or extent of acinar cell proliferation.


regulation of nematode larval development, heterochronic

Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.


Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine <=> salvigenin + S-adenosyl-L-homocysteine + H+.


negative regulation of compound eye pigmentation

Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.


biphenyl synthase activity

Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2.


Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate.


protein-N-terminal asparagine amidohydrolase activity

Catalysis of the reaction: N-terminal L-asparaginyl-[protein] + H+ + H2O = N-terminal L-aspartyl-[protein] + NH4+. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein.


pronephros formation

The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


specification of segmental identity, head

The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.


mannan synthase activity

Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.


delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity

Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose.


protein K33-linked ubiquitination

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.


regulation of response to butan-1-ol

Any process that modulates the frequency, rate or extent of response to butan-1-ol.


RNA-templated viral transcription

A transcription process that uses viral RNA as a template.


circumnutation

The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.


cellular response to dithiothreitol

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.


metanephric macula densa development

The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.


trans-synaptic signaling by nitric oxide, modulating synaptic transmission

Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.


cell wall macromolecule catabolic process involved in cell wall disassembly

The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.


acyl-CoA 11-(E)-desaturase activity

Catalysis of the reaction: an 11,12-saturated fatty acyl-CoA + 2 Fe(II)-[cytochrome b5] + 2 H+ + O2 = an (11E)-delta11-fatty acyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O.


negative regulation of inflammasome-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of an inflammasome-mediated signaling pathway.


TORC1 signaling

A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.


UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+.


Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.


synaptic transmission, noradrenergic

The vesicular release of noradrenaline (norepinephrine) a presynapse, across a chemical synapse, the subsequent activation of noradrenaline receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.


arabinonate dehydratase activity

Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H2O.


Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.


Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside.


transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.


autophagosome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.


regulation of defense response by callose deposition

Any process that modulates the frequency, rate or extent of defense response by callose deposition.


Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.


regulation of cardiac chamber morphogenesis

Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.


Latia-luciferin monooxygenase (demethylating) activity

Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.


mycocerosate synthase activity

Catalysis of the reaction: acyl-CoA + 7n H+ + n methylmalonyl-CoA + 2n NADPH = n CO2 + n CoA + n H2O + multi-methyl-branched acyl-CoA + 2n NADP+.


positive regulation of embryo sac egg cell differentiation

Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation.


negative regulation of embryo sac egg cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation.


plastid rRNA transcription

The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.


Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.


cellular response to differentiation-inducing factor 2

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one stimulus.


scytalone dehydratase activity

Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H2O.


diethyl 2-methyl-3-oxosuccinate reductase activity

Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ = diethyl 2-methyl-3-oxosuccinate + H+ + NADPH.


plant-type ovary development

The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.


Catalysis of the reaction: 2-phenylethanol + acetyl-CoA = phenethyl acetate + coenzyme A.


Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-.


fungal-type cell wall disassembly

A cellular process that results in the breakdown of a fungal-type cell wall.


AGU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an AGU codon.


lipid antigen assembly with MHC class Ib protein complex

The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.


choline biosynthetic process via phosphoryl-ethanolamine

The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.


alpha-glucan catabolic process

The chemical reactions and pathways resulting in the breakdown of alpha-glucans.


phosphagen biosynthetic process

The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.


Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal.


calcidiol binding

Binding to calcidiol.


regulation of recycling endosome localization within postsynapse

Any process that modulates the frequency, rate or extent of transport or maintenance of location of a postsynaptic recycling endosome within the postsynapse.


Catalysis of the reaction: S-adenosyl-L-methionine + 7,8,4'-trihydroxyflavone <=> H+ + S-adenosyl-L-homocysteine + 7,4'-dihydroxy, 8-methoxyflavone.


cytoskeleton-nuclear membrane anchor activity

The binding activity of a molecule that brings together a cytoskeletal protein or protein complex and a nuclear membrane lipid or membrane-associated protein, in order to maintain the localization of the cytoskeleton at a specific location of the nuclear membrane.


Catalysis of the reaction: N-formylmethanofuran + A + H2O + H+ = AH(2) + CO2 + methanofuran.


modulation of nutrient release by host

Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


macula densa development

The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.


glycine dehydrogenase (cytochrome) activity

Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c.


T cell inhibitory signaling pathway

The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.


signaling receptor activity

Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.


ecdysteroid catabolic process

The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.


tRNA 5'-end processing

The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.


hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity

Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate.


protoporphyrinogen oxidase activity

Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.


regulation of amino acid export

Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.


cellular response to fluoxetine

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.


Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.


arabinose catabolic process

The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.


Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+.


regulation of presynaptic cytosolic calcium ion concentration

Any process that regulates the concentration of calcium in the presynaptic cytosol.


Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid.


4-chlorobiphenyl metabolic process

The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.


negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.


response to histidine

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.


cellular response to thyrotropin-releasing hormone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.


G protein-coupled bile acid receptor activity

Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


negative regulation of activated T cell autonomous cell death

Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.


nurse cell nucleus anchoring

Attachment of the nurse cell nucleus to the plasma membrane.


pronephros structural organization

The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP.


crotonaldehyde redutase activity

Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP.


positive regulation of neurotrophin TRK receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.


inhibitory chemical synaptic transmission

Synaptic transmission that results in an inhibitory postsynaptic potential.


Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine.


establishment of protein localization to juxtaparanode region of axon

The directed movement of a protein to the juxtaparanode region of an axon.


iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide

The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.


endothelial cell activation within high endothelial venule involved in immune response

A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.


colicin transmembrane transporter activity

Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.


Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate.


low-affinity basic amino acid transmembrane transporter activity

Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.


regulation of cell morphogenesis involved in conjugation with cellular fusion

Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion.


centromere clustering

The process by which centromeres/kinetochores become localized to clusters.


viral extrusion

The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded.


Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol.


iodophenol O-methyltransferase activity

Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H+.


sulfide dehydrogenase activity

Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S + reduced cytochrome c.


negative regulation of heart looping

Any process that stops, prevents or reduces the frequency, rate or extent of heart looping.


ABC-type ferric iron transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).


regulation of corticotropin-releasing hormone receptor activity

Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity.


regulation of gastric emptying

Any process that modulates the frequency, rate or extent of any gastric emptying process, the process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.


propanediol transmembrane transporter activity

Enables the transfer of propanediol from one side of a membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.


cyclohexanol dehydrogenase activity

Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.


negative regulation of acid-sensing ion channel in another organism

Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism.


maltose transmembrane transporter activity

Enables the transfer of maltose from one side of a membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch.


sequoyitol dehydrogenase activity

Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD+ = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H+ + NADH.


hydroxyisourate hydrolase activity

Catalysis of the reaction: 5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+.


monoterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.


positive regulation of oospore formation

Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.


3-dehydroquinate dehydratase activity

Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H2O.


Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.


cell wall pectin metabolic process

The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.


perturbation of host cell cycle progression

A process in which a symbiont interferes with the normal progression through the host cell cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction.


mitochondrial mRNA processing

Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.


phenylpyruvate decarboxylase activity

Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.


IgM receptor activity

Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


detection of activity

The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.


(+)-alpha-barbatene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-alpha-barbatene + diphosphoric acid.


lysobisphosphatidic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.


maintenance of nucleus location

Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.


regulation of platelet rolling

Any process that modulates the frequency, rate or extent of platelet rolling.


Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.


horizontal cell localization

Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.


positive regulation of interleukin-6-mediated signaling pathway

Any process that increases the rate, frequency or extent of an interleukin-6-mediated signaling pathway.


aerobic respiration, using carbon monoxide as electron donor

The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.


epidermal growth factor receptor signaling pathway involved in lung development

The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.


tetrachloroethylene metabolic process

The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent.


Catalysis of the reaction: UDP-alpha-D-glucose + 2',3,4,4',6'-pentahydroxychalcone <=> H+ + 2',3,4,4',6'-pentahydroxychalcone 4'-O-beta-D-glucoside + UDP.


fatty acid amide hydrolase activity

Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.


chemokine (C-X-C motif) ligand 12 production

The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


UCA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UCA codon.


transition metal ion binding

Binding to a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.


endocardial cushion cell fate determination

The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.


detection of hot stimulus involved in thermoception

The series of events in which a hot stimulus is received and converted into a molecular signal as part of thermoception.


Catalysis of the reaction: (6E)-8-hydroxygeraniol + 2 NADP <=> (6E)-8-oxogeranial + 2 NADPH + 2 H+.


follicle cell of egg chamber migration

The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.


corneocyte desquamation

The delamination process that results in the shedding of a corneocyte from the surface of the epidermis.


aspartate N-acetyltransferase activity

Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H+.


Catalysis of the reaction: cyclohexane-1,3-dione + H2O = 5-oxohexanoate + H+.


response to nitrogen dioxide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.


acetoin metabolic process

The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source.


heparin lyase activity

Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.


negative regulation of glycerol transport

Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


mesonephric nephron morphogenesis

The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.


endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)

Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.


meiotic prometaphase I

The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.


Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+.


formation of quadruple SL/U4/U5/U6 snRNP

Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.


snRNA 2'-O-methylation

The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule.


alpha-copaene catabolic process

The chemical reactions and pathways resulting in the breakdown of alpha-copaene.


positive regulation of cellular defense response

Any process that activates or increases the frequency, rate or extent of cellular defense response.


floor plate formation

The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.


kynurenic acid metabolic process

The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.


regulation of protein folding in endoplasmic reticulum

Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).


biliberdin reductase NAD+ activity

Catalysis of the reaction: bilirubin + NAD+ = biliverdin + NADH+ H+.


carbon-monoxide oxygenase activity

Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.


metanephric connecting tubule development

The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.


L-xylitol catabolic process to xylulose 5-phosphate

The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.


NADPH-dependent curcumin reductase activity

Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+.


L-fucose mutarotase activity

Catalysis of the reaction: alpha-L-fucose = beta-L-fucose.


calcium-dependent self proteolysis

The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.


negative regulation of premature acrosome loss

Any process that stops, prevents or reduces the discharge, by sperm, of a single, anterior secretory granule before the sperm reaches to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents.


negative regulation of endothelial cell-matrix adhesion via fibronectin

Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.


Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O.


negative regulation of toll-like receptor 12 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.


response to biphenyl

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.


abducens nerve development

The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.


Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate.


L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine

The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine.


C-C motif chemokine 2 receptor activity

Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


glucosylglycerol biosynthetic process

The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.


mesodermal-endodermal cell signaling involved in heart induction

Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction.


arginine catabolic process to ornithine

The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.


spheroidene monooxygenase activity

Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O.


stress response to nickel ion

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus.


cellular modified histidine metabolic process

The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


cephalic furrow formation

Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome.


organonitrogen compound metabolic process

The chemical reactions and pathways involving organonitrogen compound.


regulation of zygosporangium development

Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.