negative regulation of methane biosynthetic process from carbon monoxide

Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide.


regulation of RNA biosynthetic process

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Any process that modulates the frequency, rate or extent of RNA biosynthetic process.


negative regulation of aflatoxin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process.


positive regulation of interleukin-16 production

Any process that activates or increases the frequency, rate, or extent of interleukin-16 production.


regulation of tetrapyrrole catabolic process

Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.


positive regulation of plasmacytoid dendritic cell cytokine production

Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.


positive regulation of sulfur amino acid metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.


negative regulation of phosphatidylglycerol biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.


regulation of DNA-templated transcription

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.


regulation of cordyol C biosynthetic process

Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process.


regulation of melanotic encapsulation of foreign target

Any process that modulates the frequency, rate or extent of melanotic encapsulation of foreign target.


regulation of DNA replication initiation involved in plasmid copy number maintenance

Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.


regulation of T-helper 1 cell cytokine production

Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production.


regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA

Any process that modulates the frequency, rate or extent of deadenylation-dependent decapping of nuclear-transcribed mRNA.


negative regulation of phosphatidylcholine metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine metabolic process.


positive regulation of initiation of premeiotic DNA replication

Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.


regulation of reductive pentose-phosphate cycle

Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle.


negative regulation of vascular endothelial growth factor production

Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production.


negative regulation of methane biosynthetic process from dimethylamine

Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine.


regulation of methyl-branched fatty acid biosynthetic process

Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.


regulation of interleukin-24 production

Any process that modulates the frequency, rate, or extent of interleukin-24 production.


regulation of mRNA stability involved in cellular response to UV

Any regulation of mRNA stability that is involved in cellular response to UV.


regulation of nucleobase-containing compound metabolic process

Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.


regulation of beta-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans.


negative regulation of macromolecule biosynthetic process

Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.


transcriptional attenuation

A negative regulation of gene expression mechanism by which bacteria and archae can direct RNA polymerase to prematurely terminate transcription in response to a specific metabolic signal.


regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.


negative regulation of interleukin-33 production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-33 production.


regulation of reverse transcription

Any process that modulates the frequency, rate or extent of reverse transcription.


positive regulation of single-strand break repair via homologous recombination

Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination.


regulation of phosphorus metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.


negative regulation of tatiopterin metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process.


positive regulation of chemokine (C-C motif) ligand 20 production

Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.


positive regulation of carotenoid biosynthetic process

Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process.


negative regulation of superoxide dismutase activity

Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity.


regulation of chemokine (C-X-C motif) ligand 1 production

Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.


regulation of rRNA catabolic process

Any process that modulates the frequency, rate or extent of rRNA catabolic process.


negative regulation of NAD+ kinase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


negative regulation of antibacterial peptide production

Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.


regulation of mitotic DNA replication initiation from late origin

Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.


regulation of fungal-type cell wall beta-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.


inactivation of paternal X chromosome by genomic imprinting

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genomic imprinting.


negative regulation of endothelin production

Any process that stops, prevents or reduces the frequency, rate or extent of endothelin production.


regulation of termination of RNA polymerase II transcription, poly(A)-coupled

Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.


positive regulation of interleukin-33 production

Any process that activates or increases the frequency, rate or extent of interleukin-33 production.


regulation of photosynthesis, dark reaction

Any process that modulates the frequency, rate or extent of photosynthesis dark reaction.


negative regulation of phosphatidylcholine biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process.


photoinhibition

The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II.


regulation of chemokine (C-X-C motif) ligand 9 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


positive regulation of phosphatidylcholine biosynthetic process

Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.


negative regulation of lipophagy

Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy.


photosystem I stabilization

The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.


positive regulation of exonuclease activity

Any process that activates or increases the frequency, rate or extent of exonuclease activity.


RNAi-mediated antiviral immunity against RNA virus

An RNAi-mediated post-transcriptional gene silencing pathway induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL4 is the primary Dicer to detect RNA viruses.


negative regulation of orcinol biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process.


regulation of connective tissue growth factor production

Any process that modulates the frequency, rate, or extent of connective tissue growth factor production.


positive regulation of phosphodiesterase I activity

Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity.


regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process

Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.


regulation of interleukin-21 production

Any process that modulates the frequency, rate, or extent of interleukin-21 production.


transcriptional attenuation by ribosome

A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.


positive regulation of transcription from RNA polymerase II promoter by oleic acid

Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.


negative regulation of gene expression

Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


regulation of interleukin-32 production

Any process that modulates the frequency, rate or extent of interleukin-32 production.


positive regulation of dendritic cell cytokine production

Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.


positive regulation of toluene catabolic process

Any process that activates or increases the frequency, rate or extent of toluene catabolic process.


positive regulation of mitotic cell cycle DNA replication

Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.


positive regulation of methane biosynthetic process from carbon monoxide

Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide.


negative regulation of cobalamin metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of a cobalamin metabolic process.


negative regulation of chemokine (C-C motif) ligand 4 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.


positive regulation of nucleobase-containing compound metabolic process

Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.


positive regulation of transcription by RNA polymerase II

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.


regulation of camalexin biosynthetic process

Any process that modulates the frequency, rate or extent of camalexin biosynthetic process.


regulation of interleukin-26 production

Any process that modulates the frequency, rate, or extent of interleukin-26 production.


regulation of interleukin-25 production

Any process that modulates the frequency, rate, or extent of interleukin-25 production.


negative regulation of syringal lignin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process.


suppression by virus of host transcription

Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors.


positive regulation of termination of DNA-templated transcription

Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.


regulation of transforming growth factor beta3 activation

Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation.


positive regulation of nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts

Any process that activates or increases the frequency, rate or extent of degradation of meiosis-specific nuclear transcribed transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.


positive regulation of interleukin-32 production

Any process that activates or increases the frequency, rate or extent of interleukin-32 production.


regulation of (+)-kotanin biosynthetic process

Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process.


negative regulation of phosphatidic acid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process.


negative regulation of toluene catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process.


negative regulation of hh target transcription factor activity

Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling.


regulation of mitotic DNA replication initiation from early origin

Any process that modulates the frequency, rate or extent of firing from an early origin of replication involved in mitotic DNA replication.


positive regulation of single stranded viral RNA replication via double stranded DNA intermediate

Any process that activates or increases the frequency, rate or extent of retroviral genome replication.


positive regulation of RNA biosynthetic process

Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.


regulation of phosphatidylcholine metabolic process

Any process that modulates the frequency, rate or extent of phosphatidylcholine metabolic process.


regulation of mitochondrial ATP synthesis coupled proton transport

Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.


positive regulation of D-erythro-sphingosine kinase activity

Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity.


positive regulation of DNA-templated transcription

Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.


positive regulation of transforming growth factor beta activation

Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation.


regulation of IP-10 production

Any process that modulates the frequency, rate, or extent of production of IP-10.


positive regulation of amphiregulin production

Any process that activates or increases the frequency, rate or extent of production of amphiregulin.


regulation of diorcinol biosynthetic process

Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process.


positive regulation of histidine biosynthetic process

Any process that activates or increases the frequency, rate or extent of histidine biosynthetic process.


regulation of diacylglycerol biosynthetic process

Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process.


activation of reciprocal meiotic recombination

Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.


siRNA-dependent pericentric heterochromatin formation

The formation of pericentric heterochromatin by a process mediated by a small interfering RNA.


regulation of methane biosynthetic process from methanethiol

Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol.


negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.


negative regulation of juvenile hormone catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.


nitrogen catabolite activation of transcription from RNA polymerase II promoter

A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.


positive regulation of brassinosteroid biosynthetic process

Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process.


positive regulation of diacylglycerol biosynthetic process

Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.


suppression by virus of host translation termination

Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA.


positive regulation of interleukin-27 production

Any process that activates or increases the frequency, rate, or extent of interleukin-27 production.


negative regulation of interleukin-35 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.


5' transitive RNA interference

An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.


positive regulation of RNA metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.


regulation of NAD+ kinase activity

Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.


regulation of thiamine diphosphate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.


regulation of polynucleotide 3'-phosphatase activity

Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity.


positive regulation of interleukin-17A production

Any process that activates or increases the frequency, rate or extent of interleukin-17A production.


positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled

Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.


positive regulation of DNA methylation

Any process that activates or increases the frequency, rate or extent of DNA methylation.


regulation of plasmacytoid dendritic cell cytokine production

Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.


positive regulation of interleukin-26 production

Any process that activates or increases the frequency, rate, or extent of interleukin-26 production.


regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.


regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends

Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends.


co-transcriptional gene silencing by RNA interference machinery

A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.


regulation of single-strand break repair via homologous recombination

Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination.


positive regulation of connective tissue growth factor production

Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.


positive regulation of methane biosynthetic process from methylamine

Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine.


positive regulation of DNA primase activity

Any process that activates or increases the frequency, rate or extent of DNA primase activity.


regulation of poly(A)-specific ribonuclease activity

Any process that modulates the rate, frequency or extent of the catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.


negative regulation of hydrogen sulfide biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process.


regulation of DNA amplification

Any process that modulates the frequency, rate or extent of DNA amplification.


regulation of inositol-polyphosphate 5-phosphatase activity

Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.


regulation of DNA replication termination

Any process that modulates the frequency, rate or extent of DNA replication termination.


suppression by virus of host translation

Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA, for example by cleavage of the host mRNAs.


positive regulation of hydrogen peroxide catabolic process

Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process.


negative regulation of transforming growth factor beta activation

Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation.


piRNA-mediated gene silencing by mRNA destabilization

A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping.


regulation of transforming growth factor beta1 activation

Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation.


regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process

Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.


induction by virus of host reticulophagy

Any process in which a virus activates or increases the frequency, rate or extent of reticulophagy in the host.


positive regulation of endoribonuclease activity

Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.


positive regulation of antibacterial peptide secretion

Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion.


positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.


regulation of strand invasion

Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.


positive regulation of mitophagy

Any process that activates or increases the frequency, rate or extent of mitophagy.


negative regulation of T-helper 1 cell cytokine production

Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production.


negative regulation of antifungal peptide production

Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.


regulation of dolichol biosynthetic process

Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.


negative regulation of electron transfer activity

Any process that stops, prevents or reduces the frequency, rate or extent of electron transfer activity.


positive regulation of amino acid biosynthetic process

Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.


regulation of glucose-6-phosphatase activity

Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.


positive regulation of DNA strand resection involved in replication fork processing

Any process that activates or increases the frequency, rate or extent of DNA strand resection involved in replication fork processing.


positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA

Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.


regulation of macrophage inflammatory protein 1 alpha production

Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


negative regulation of sulfur amino acid metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.


negative regulation of interleukin-11 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.


positive regulation of mitochondrial DNA replication

Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.


negative regulation of transforming growth factor beta2 activation

Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation.


regulation of thiamine biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.


regulation of rRNA stability

Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.


positive regulation of phosphatidate phosphatase activity

Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity.


negative regulation of estrogen biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process.


positive regulation of termination of RNA polymerase II transcription

Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.


positive regulation of mRNA cis splicing, via spliceosome

Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome.


negative regulation of interleukin-22 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.


regulation of type IV site-specific deoxyribonuclease activity

Any process that modulates the frequency, rate or extent of a type IV restriction endodeoxyribonuclease activity.


negative regulation of chemokine (C-C motif) ligand 20 production

Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.


negative regulation of UDP-N-acetylglucosamine biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of the UDP-N-acetylglucosamine biosynthetic process.


suppression by virus of host mRNA processing

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.


positive regulation of telomere maintenance via semi-conservative replication

Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.


regulation of chitin biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.


negative regulation of chemokine (C-X-C motif) ligand 9 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.


positive regulation of mRNA alternative polyadenylation

Any process that activates or increases the frequency, rate or extent of mRNA alternative polyadenylation.


positive regulation of error-prone translesion synthesis

Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.


positive regulation of sulfate assimilation

Any process that activates or increases the frequency, rate or extent of sulfate assimilation.


regulation of interleukin-35 production

Any process that modulates the frequency, rate, or extent of interleukin-35 production.


regulation of UDP-glucose catabolic process

Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.


positive regulation of capsule polysaccharide biosynthetic process

Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


positive regulation of exoribonuclease activity

Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.


regulation of pre-miRNA processing

Any process that modulates the frequency, rate or extent of pre-microRNA processing.


negative regulation of removal of superoxide radicals

Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals.


regulation of exoribonuclease activity

Any process that modulates the frequency, rate or extent of exoribonuclease activity.


induction of phytoalexin biosynthetic process

The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection.


regulation of fumagillin biosynthetic process

Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process.


positive regulation of transforming growth factor beta3 activation

Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation.


regulation of demethylkotanin biosynthetic process

Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.


regulation of interleukin-27 production

Any process that modulates the frequency, rate, or extent of interleukin-27 production.


positive regulation of ent-pimara-8(14),15-diene biosynthetic process

Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.


regulation of transforming growth factor beta activation

Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.


regulation of mitochondrial mRNA catabolic process

Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.


positive regulation of camalexin biosynthetic process

Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.


negative regulation of ent-pimara-8(14),15-diene biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.


positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity

Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.


negative regulation of sulfur metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.


negative regulation of B cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.


negative regulation of phosphatidylserine metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine metabolic process.


regulation of photosynthesis, light reaction

Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis.


regulation of transcription-coupled nucleotide-excision repair

Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.


positive regulation of polynucleotide 3'-phosphatase activity

Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity.


regulation of sulfate assimilation

Any process that modulates the frequency, rate or extent of sulfate assimilation.


negative regulation of cellular biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.


regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.


regulation of glycolytic fermentation to ethanol

Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol.


regulatory ncRNA-mediated heterochromatin formation

A heterochromatin formation-based gene silencing process mediated by a regulatory non-coding RNA molecule that occur before the beginnning of trancription.


positive regulation of phosphate metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.


regulation of chemokine (C-C motif) ligand 6 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


positive regulation of reticulophagy

Any process that increases the frequency, rate or extent of reticulophagy.


negative regulation of sarcinapterin metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process.


regulation of ascospore wall beta-glucan biosynthetic process

Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.


negative regulation of myeloid dendritic cell cytokine production

Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.


regulation of fructose 1,6-bisphosphate 1-phosphatase activity

Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.


negative regulation of photosynthesis, light reaction

Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.


positive regulation of interleukin-20 production

Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.


negative regulation of interleukin-17A production

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17A production.


photosystem II stabilization

The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.


positive regulation of DNA recombination at telomere

Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.


negative regulation of IP-10 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.


regulation of interleukin-22 production

Any process that modulates the frequency, rate, or extent of interleukin-22 production.


positive regulation of gene expression via CpG island demethylation

An epigenetic gene regulation mechanism that positively regulates gene expression by demethylation of cytosine residues in chromosomal CpG islands. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.


negative regulation of amino acid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process.


positive regulation of interleukin-11 production

Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.


regulation of violaceol II biosynthetic process

Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process.


regulation of membrane lipid metabolic process

Any process that modulates the frequency, rate or extent of membrane lipid metabolic process.


negative regulation of xenophagy

Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy.


regulation of diacylglycerol kinase activity

Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity.


negative regulation of amylopectin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process.


negative regulation of interleukin-15 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.


activation of recombination (HML)

The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.


RNAi-mediated antiviral immunity against DNA virus

An RNAi-mediated post-transcriptional gene silencing pathway induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or inhibition of translation. In plants, DCL3 is the primary Dicer to detect DNA viruses.


negative regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


negative regulation of thyroid hormone generation

Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.


negative regulation of chemokine (C-C motif) ligand 1 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


negative regulation of interleukin-21 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.


suppression by virus of host mRNA transcription via inhibition of RNA polymerase II activity

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host mRNA transcription by directly inhibiting RNA polymerase II activity.


regulation of methane biosynthetic process from methylamine

Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine.


regulation of syringal lignin catabolic process

Any process that modulates the frequency, rate or extent of syringal lignin catabolic process.


regulation of polyamine biosynthetic process

Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.


positive regulation of transforming growth factor beta2 activation

Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation.


regulation of interleukin-17A production

Any process that modulates the frequency, rate or extent of interleukin-17A production.


dosage compensation by hyperactivation of X chromosome

Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.


positive regulation of tRNA catabolic process

Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.


negative regulation of isoprenoid metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.


negative regulation of aggrephagy

Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy.


positive regulation of thiamine biosynthetic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.


negative regulation melanotic encapsulation of foreign target

Any process that stops, prevents or reduces the frequency, rate or extent of melanotic encapsulation of foreign target.


The organization of chromatin into heterochromatin at the pericentric region of a chromosome.


negative regulation of sinapate ester biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.


negative regulation of glial cell-derived neurotrophic factor production

Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor production.


regulation of plant-type cell wall cellulose biosynthetic process

Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.


regulation of replication fork arrest at rDNA repeats

Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.


positive regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.


negative regulation of phosphorus utilization

Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization.


regulation of cellular biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.


regulation of syringal lignin biosynthetic process

Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.


photosynthetic state transition

A regulation of the phtosynthetic light reaction in which the light harvesting antenna complexes transition between photosystems.


positive regulation of isoprenoid metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.


negative regulation of mitochondrial ATP synthesis coupled proton transport

Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.


spatial regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination

Any process that modulates the distribution of sites along the chromosome where meiotic DNA double-strand break formation takes place as part of reciprocal meiotic recombination.


positive regulation of phosphorus metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.


positive regulation of interleukin-15 production

Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.


regulation of phosphatidate phosphatase activity

Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity.


positive regulation of estrogen biosynthetic process

Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process.


facultative heterochromatin formation

The compaction of chromatin into a conformation that is refactory to transcription but that be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression).


negative regulation of methane biosynthetic process from methanethiol

Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol.


positive regulation of melanization defense response

Any process that increases the rate or extent of the melanization defense response during injury or invasion.


positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.


negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity

Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.


positive regulation of interleukin-34 production

Any process that activates or increases the frequency, rate or extent of interleukin-34 production.


regulation of termination of RNA polymerase II transcription

Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription.


positive regulation of juvenile hormone metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.


regulation of mRNA stability involved in response to stress

Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.


negative regulation of phosphatidylcholine catabolic process

Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.


regulation of amphiregulin production

Any process that modulates the frequency, rate, or extent of production of amphiregulin.


positive regulation of interleukin-25 production

Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.


regulation of brassinosteroid biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.


positive regulation of rRNA processing

Any process that activates or increases the frequency, rate or extent of rRNA processing.


negative regulation of MHC class I biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.


positive regulation of hydrogen sulfide biosynthetic process

Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.


negative regulation of methane biosynthetic process from dimethyl sulfide

Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.


positive regulation of interleukin-35 production

Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.


retrotransposon silencing by RNA-directed DNA methylation

A retrotransposon silencing mechanism mediated by RNA-directed DNA methylation. RNA-directed DNA methylation is a gene silencing process in which small interfering RNAs (siRNAs) guide DNA methylation to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. This results in a heterochromatin assembly, a chromatin conformation that is refractory to transcription.


positive regulation of gene expression

Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA).


regulation of alpha-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.


positive regulation of inositol-polyphosphate 5-phosphatase activity

Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.


positive regulation of interleukin-22 production

Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.


positive regulation of glycolytic fermentation to ethanol

Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol.


autosome genomic imprinting

The establishment of epigenetic modifications (imprints) in autosomal (non-sexual) chromosomes during gametogenesis, and propagation of these imprints during the organism's life. Genomic imprinting leads to an asymmetry between the maternal and paternal alleles and differential expression of the corresponding alleles. This can happen through heterochromatin formation or differential chromatin loop formation.


positive regulation of pyrimidine nucleotide biosynthetic process

Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.


negative regulation of ergosterol biosynthetic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.


positive regulation of DNA ligase activity

Any process that activates or increases the frequency, rate or extent of DNA ligase activity.


The formation of heterochromatin into a heterochromatin domain, enriched in histone H3 methylated on lysine 9 (H3K9me), by a process mediated by a small interfering piRNA.


positive regulation of chemokine (C-X-C motif) ligand 1 production

Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.


positive regulation of amylopectin catabolic process

Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process.


positive regulation of T-helper 1 cell cytokine production

Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production.


negative regulation of macrophage inflammatory protein-1 gamma production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.


suppression by virus of host transcription initiation from RNA polymerase II promoter

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.


positive regulation of phytol biosynthetic process

Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process.


regulation of mRNA alternative polyadenylation

Any process that modulates the frequency, rate or extent of mRNA alternative polyadenylation.


positive regulation of mitotic recombination-dependent replication fork processing

Any process that activates or increases the frequency, rate or extent of mitotic recombination-dependent replication fork processing. Regulation of mitotic recombination prevents recombination between inappropriate homologous sequences. Proteins involved in homologous recombination are required for replication restart.


negative regulation of interleukin-7 production

Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.


regulation of hydrogen sulfide biosynthetic process

Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process.


regulation of exodeoxyribonuclease activity

Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity.


regulation of cellulose biosynthetic process

Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.


regulation of mRNA cis splicing, via spliceosome

Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.


RNAi-mediated antiviral immune response

A post-transcriptional gene silencing pathway mediated by the action of regulatory RNAs that protects against foreign organism invasion by restricting viral replication and dissemination.


regulation of myeloid dendritic cell cytokine production

Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.


regulation of (1->3)-beta-D-glucan biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.


positive regulation of DNA amplification

Any process that activates or increases the frequency, rate or extent of DNA amplification.


regulation of electron transfer activity

Any process that modulates the frequency, rate or extent of electron transfer activity.


negative regulation of cellulose biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.


epigenetic programing of female pronucleus

The global programming of epigenetic modifications in the female pronucleus of the newly fertilized zygote. The maternal genome is protected from global DNA demethylation before the first division of the zygote, and instead undergoes passive, replication-dependent demethylation during early embryogenesis, arising from inhibition of the DNA maintenance methyltransferase Dnmt1.


positive regulation of auxin biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.


positive regulation of chemokine (C-C motif) ligand 6 production

Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).


regulation of DNA double-strand break processing

Any process that modulates the frequency, rate or extent of DNA double-strand break processing.


regulation of interleukin-9 production

Any process that modulates the frequency, rate, or extent of interleukin-9 production.


regulation of RNA metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.


positive regulation of reverse transcription

Any process that activates or increases the frequency, rate or extent of reverse transcription.


constitutive heterochromatin formation

The compaction of chromatin into a conformation that is refactory to transcription.


positive regulation of auxin metabolic process

Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.


regulation of 3'-UTR-mediated mRNA stabilization

Any process that modulates the frequency, rate or extent of 3'-UTR-mediated mRNA stabilization.


regulation of phenylpropanoid metabolic process

Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.


regulation of juvenile hormone biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.


negative regulation of brassinosteroid biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.


negative regulation of type III interferon production

Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.


regulation of chemokine (C-C motif) ligand 20 production

Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.


regulation of chemokine (C-C motif) ligand 1 production

Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.


regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source

A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.


regulation of capsule polysaccharide biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.


negative regulation of tatiopterin biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process.


negative regulation of macrophage inflammatory protein 1 alpha production

Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.


negative regulation of spermidine biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process.


negative regulation of cordyol C biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process.


regulation of estrogen biosynthetic process

Any process that modulates the frequency, rate or extent of estrogen biosynthetic process.


suppression by virus of host type I interferon production

Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.


regulation of endothelin production

Any process that modulates the frequency, rate or extent of endothelin production.


positive regulation of transcription by galactose

Any process involving galactose that activates or increases the rate of transcription.


negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.


positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway

Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.


hereditary painful callosities

biolink:Disease biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:NamedThing biolink:ThingWithTaxon

Hereditary painful callosities is a nummular palmoplantar keratoderma characterized by the development of painful keratotic lesions over pressure points in hands and feet. A few families have been described. Transmission is autosomal dominant. Successful analgesia can be obtained with tretinoin.


X-linked sideroblastic anemia with ataxia

A rare syndromic, inherited form of sideroblastic anemia in which the cause of the disease is a mutation in the ABCB7 gene and is characterized by mild to moderate anemia (with hypochromia and microcytosis) and early-onset, non- or slowly progressive spinocerebellar ataxia.


4-ketotorulene 3-hydroxylase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O.


Undifferentiated Juvenile Idiopathic Arthritis

A category of juvenile idiopathic arthritis that does not fulfill any single category or has criteria for more than one category.


diacetyl reductase ((S)-acetoin forming) activity

Catalysis of the reaction: (S)-acetoin + NAD+ = diacetyl + H+ + NADH.


(+)-abscisic acid 8'-hydroxylase activity

Catalysis of the reaction: (+)-abscisate + H+ + NADPH + O2 = (+)-8'-hydroxyabscisate + H2O + NADP+.


cysteine-type deNEDDylase activity

An thiol-dependent isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.


corolla development

The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.


Stage IVB Unknown Primary Tumor (Except for EBV-Related and HPV-Related Tumors) and Metastatic Cervical Adenopathy AJCC v8

Stage IVB includes: T0, N3, M0. T0: No evidence of primary tumor. N3: Metastasis in a cervical lymph node larger than 6 cm in greatest dimension and ENE(-); or metastases in a single ipsilateral cervical lymph node larger than 3 cm in greatest dimension and ENE(+); or metastases in multiple ipsilateral, contralateral, or bilateral cervical lymph nodes, any size and ENE(+) in any node. M0: No distant metastasis. (AJCC 8th Ed.)


Unknown Primary Tumor (Except for EBV-Related and HPV-Related Tumors) and Metastatic Cervical Adenopathy by AJCC v8 Stage

A term that refers to the staging of unknown primary tumor (except for EBV-related and HPV-related tumors) and metastatic cervical adenopathy according to the American Joint Committee on Cancer, 8th edition.


Stage IVA Unknown Primary Tumor (Except for EBV-Related and HPV-Related Tumors) and Metastatic Cervical Adenopathy AJCC v8

Stage IVA includes: T0, N2, M0. T0: No evidence of primary tumor. N2: Metastasis in a single ipsilateral or contralateral cervical lymph node 3 cm or smaller in greatest dimension and ENE(+); or metastasis in a single ipsilateral cervical lymph node larger than 3 cm but not larger than 6 cm in greatest dimension and ENE(-); or metastases in multiple ipsilateral cervical lymph nodes, none larger than 6 cm in greatest dimension and ENE(-); or metastases in bilateral or contralateral cervical lymph nodes, none larger than 6 cm in greatest dimension and ENE(-). M0: No distant metastasis. (AJCC 8th Ed.)


Stage IVC Unknown Primary Tumor (Except for EBV-Related and HPV-Related Tumors) and Metastatic Cervical Adenopathy AJCC v8

Stage IVC includes: T0, Any N, M1. T0: No evidence of primary tumor. M1: Distant metastasis. (AJCC 8th Ed.)


Stage III Unknown Primary Tumor (Except for EBV-Related and HPV-Related Tumors) and Metastatic Cervical Adenopathy AJCC v8

Stage III includes: T0, N1, M0. T0: No evidence of primary tumor. N1: Metastasis in a single ipsilateral lymph node, 3 cm or smaller in greatest dimension and ENE (extranodal extension)(-). M0: No distant metastasis. (AJCC 8th Ed.)


Recurrent Metastatic Merkel Cell Carcinoma

The reemergence of a metastatic Merkel cell carcinoma after a period of remission.


Recurrent Metastatic Malignant Neoplasm

The reemergence of a metastatic malignant neoplasm after a period of remission.


Recurrent Metastatic Melanoma

The reemergence of metastatic melanoma after a period of remission.


Recurrent Carcinoma of Unknown Primary

The reemergence of carcinoma from an unknown primary after a period of remission.


Recurrent Metastatic Digestive System Carcinoma

The reemergence of a metastatic digestive system carcinoma after a period of remission.


Recurrent Pseudomyxoma Peritonei

The reemergence of pseudomyxoma peritonei after a period of remission.


Recurrent Metastatic Malignant Neoplasm in the Leptomeninges

The reemergence of a metastatic malignant neoplasm in the leptomeninges after a period of remission.


Recurrent Metastatic Gastric Carcinoma

The reemergence of metastatic gastric carcinoma after a period of remission.


Recurrent Metastatic Skin Squamous Cell Carcinoma

The reemergence of a metastatic skin squamous cell carcinoma after a period of remission.


areolar gland

biolink:GrossAnatomicalStructure biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A sebaceous glands in the areola surrounding the nipple.


Catalysis of the movement of lysophosphatidylcholine from the exoplasmic to the cytosolic leaftlet of a membrane, using energy from the hydrolysis of ATP.


interleukin-3 production

The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


micronucleus organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.


perturbation of host B-cell mediated immune response

A process in which an organism effects a change that affects the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


suppression of host B-cell mediated immune response

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Germinative Follicular Epithelium

biolink:AnatomicalEntity biolink:OrganismalEntity biolink:BiologicalEntity biolink:NamedThing biolink:PhysicalEssence biolink:SubjectOfInvestigation biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent


Mitochondrially Inherited Nonsyndromic Sensorineural Deafness

A maternally inherited form of nonsyndromic sensorineural deafness that is caused by a mutation in any of several mitochondrial genes.


Deafness due to Connexin 26 Gene Anomaly

Congenital deafness caused by mutations in the gene GJB2 (deafness gene).


Complete neonatal hearing loss

Complete loss of the ability to detect or understand sounds present in an infant within its first month after birth.


Neonatal hearing loss

Partial or complete loss of the ability to detect or understand sounds present in an infant within its first month after birth.


autosomal recessive nonsyndromic hearing loss 1A

An autosomal recessive disorder caused by mutations in the GJB2 gene, encoding gap junction beta-2 protein. The condition is characterized by profound sensorineural hearing loss and may be associated with vestibular dysfunction.


central hearing loss

Hearing loss resulting from disorders of the central nervous system auditory pathways.


autosomal recessive nonsyndromic hearing loss 49

An autosomal recessive disorder caused by mutations in the MARVELD2 gene, encoding MARVEL domain-containing protein 2. The condition is characterized by profound prelingual deafness.


autosomal dominant nonsyndromic hearing loss 36

Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the TMC1 gene.


Hearing Loss, Functional

Hearing loss in the absence of auditory system pathology.


autosomal recessive nonsyndromic hearing loss 36

Any autosomal recessive nonsyndromic deafness in which the cause of the disease is a mutation in the ESPN gene.


autosomal recessive nonsyndromic hearing loss 28

An autosomal recessive disorder caused by mutations in the TRIOBP gene, encoding TRIO and F-actin-binding protein. The condition is characterized by severe to profound sensorineural hearing loss.


Partial neonatal hearing loss

Partial loss of the ability to detect or understand sounds present in an infant within its first month after birth.


autosomal recessive nonsyndromic hearing loss 39

An autosomal recessive disorder caused by mutations in the HGF gene, encoding hepatocyte growth factor receptor. It is characterized by profound deafness.


noise induced hearing loss

A condition in which a person loses the ability to hear due to exposure to high intensity sound.


autosomal dominant nonsyndromic hearing loss 41

Any autosomal dominant nonsyndromic deafness in which the cause of the disease is a mutation in the P2RX2 gene.


hearing loss, X-linked 4

Any X-linked nonsyndromic deafness in which the cause of the disease is a mutation in the SMPX gene.


X-linked hereditary sensory and autonomic neuropathy with hearing loss

This syndrome is characterized by the association of an axonal sensory and autonomic neuropathy with hearing loss.


Sensory hearing loss

Hearing loss caused by damage to the cochlea in the inner ear.


severe intellectual disability-progressive spastic diplegia syndrome

Severe intellectual disability-progressive spastic diplegia syndrome is a rare condition that has been described in a few people with severe intellectual disability. Other signs and symptoms include progressive microcephaly (very small head); ataxia (lack of coordination); spasticity ; and/or skin, hair and mild facial anomalies. It is caused by changes (mutations) in the CTNNB1 gene and it is inherited in an autosomal dominant fashion. Treatment is based on the signs and symptoms present in each person.


hand dermatosis

Skin conditions characterized by dense infiltration of inflammatory cells (neutrophils) in the affected tissue. They arise in reaction to some underlying systemic illness. A neutrophilic dermatosis may be seen in isolation or more than one type may occur in the same individual.


pyromania

A disorder characterized by a fascination with fire and recurrent episodes of fire setting during which the individual experiences a rising subjective sense of tension before the fire setting and a sense of gratification or relief when setting the fire. There is no ulterior motive (such as monetary gain or the expression of political ideology) to the fire setting.


arthus reaction

A localized vasculitis resulting from deposition of antibody-antigen complexes.


L(+)-tartrate dehydratase activity

Catalysis of the reaction: L-tartrate = H2O + oxaloacetate.


Testicular Mixed Choriocarcinoma and Teratoma

A malignant mixed germ cell tumor arising from the testis.  It is characterized by the presence of a teratomatous component and malignant syncytiotrophoblastic cells.


eyelid degenerative disorder

A neurodegenerative disease that involves the eyelid.


positive regulation of protein localization to adherens junction

Any process that activates or increases the frequency, rate or extent of protein localization to adherens junction. An adherens junction is a cell-cell junction composed of the epithelial cadherin-catenin complex at which the cytoplasmic face of the plasma membrane is attached to actin filaments.


C-19 gibberellin 2-beta-dioxygenase activity

Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons.


gibberellin 2-beta-dioxygenase activity

Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.


C-20 gibberellin 2-beta-dioxygenase activity

Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons.


glutamate catabolic process via L-citramalate

The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate.


hyperphosphatasia with intellectual disability syndrome 2

Any hyperphosphatasia-intellectual disability syndrome in which the cause of the disease is a mutation in the PIGO gene.


External Prosthetic Device Pain

biolink:PhenotypicFeature biolink:DiseaseOrPhenotypicFeature biolink:BiologicalEntity biolink:NamedThing biolink:ThingWithTaxon

Pain that is associated with an external artificial replacement device.


benign neoplasm of endometrium

A benign neoplasm that involves the endometrium.


severe pre-eclampsia

Preeclampsia with a systolic blood pressure of 160 mmHg or higher, or a diastolic blood pressure of 110 mmHg or higher on two occasions at least 4 hours apart while on bedrest. It is associated with thrombocytopenia (platelets less than 100,000 per microliter), impaired liver function (twice normal elevation of hepatic transaminases; severe, persistent right upper quadrant or epigastric pain), progressive renal insufficiency (serum creatinine greater than 1.1 mg/dL or doubling of baseline in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances.


corniculate cartilage

The corniculate cartilages (cartilages of Santorini) are two small conical nodules consisting of yellow elastic cartilage, which articulate with the summits of the arytenoid cartilages and serve to prolong them posteriorly and medially. They are situated in the posterior parts of the aryepiglottic folds of mucous membrane, and are sometimes fused with the arytenoid cartilages. [WP,unvetted].


Malignant nasopharyngeal neoplasm recurrent

The reemergence of a nasopharyngeal malignant neoplasm after a period of remission.


Lymphoma of kidney

A lymphoma that arises from the kidney. There is no evidence of a systemic lymphoproliferative disorder.


detection of jasmonic acid stimulus

The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.


negative regulation of RNA import into nucleus

Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.


Peritoneal Histiocytic Nodule

A nodule in the peritoneum composed of benign histiocytes.


Douglas' pouch

The rectouterine pouch (or rectouterine excavation, rectovaginal, Ehrhardt-Cole Recess or Pouch of Douglas) is the extension of the peritoneal cavity between the rectum and back wall of the uterus in the female human body. The rectouterine pouch is used in the treatment of end-stage renal failure in patients who are treated by peritoneal dialysis. The tip of the dialysis catheter is placed into the deepest point of the pouch. In women it is the deepest point of the peritoneal cavity, posterior to (behind) the uterus and anterior to (in front of) rectum. (The pouch on the other side of the uterus is the vesicouterine excavation. ) It is near the posterior fornix of the vagina. In men, the region corresponding to the rectouterine pouch is the rectovesical excavation, which lies between the urinary bladder and rectum. (There is no equivalent to the vesicouterine excavation.).


uterovesical pouch

The peritoneum over the rectum and the bladder is continued over the intestinal surface and fundus of the uterus on to its vesical surface, which it covers as far as the junction of the body and cervix uteri, and then to the bladder, forming here a second, but shallower, pouch, the vesicouterine excavation (or uterovesical pouch). The vesicouterine excavation is close to the anterior fornix of the vagina.


cholane derivative

Any steroid (or derivative) based on a cholane skeleton.


A steroid compound with a structure based on a 24-carbon (cholane) skeleton.


follicular dendritic cell sarcoma of mediastinum

A rare follicular dendritic cell sarcoma that affects the structures of the mediastinum.


streptococcus pneumoniae discitis

Discitis caused by infection with Streptococcus pneumoniae.


atrial septal defect 9

Any atrial heart septal defect in which the cause of the disease is a mutation in the GATA6 gene.


Ewing sarcoma of bone

A small round cell bone tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It often affects the diaphysis or metaphyseal-diaphyseal portion of long bones. Clinical findings include pain and a mass in the involved area. fever, anemia, leukocytosis, and an increased sedimentation rate are often seen. X-ray examination reveals osteolytic lesions. The prognosis depends on the stage, anatomic location, and size of the tumor.


depressor labii inferioris

A muscle of facial expression, innervated by the facial nerve, attached to the skin of the lower lip, orbicularis oris muscle, and mandible, and superficial and lateral to the mentalis muscle. See Diogo et al., 2009; Burrows et al., 2011).


negative regulation of store-operated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.


negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity

Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.


negative regulation of high voltage-gated calcium channel activity

Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity.


regulation of light-activated voltage-gated calcium channel activity

Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity.


The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-).


acute hypotension

Acute form of hypotension (disease).


Pancreatic Mucinous-Cystic Neoplasm, High Grade

A non-invasive mucinous cystic neoplasm that arises from the pancreas and is characterized by the presence of severe dysplasia.  The neoplastic columnar mucin-producing epithelial cells form papillae with irregular branching and budding.  There is nuclear stratification, prominent nucleoli, and cellular pleomorphism.  Mitotic activity is present and the mitoses may be atypical.


peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine

The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine.


peptidyl-arginine hydroxylation

The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.


peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine

The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine.


oxylipin biosynthetic process

The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.


positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus

Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.


Parenteral Nutrition - Associated Cholestasis

Cholestasis that results from prolonged total parenteral nutrition. It is caused by diminished bile flow from the liver into the duodenum. It may result in cirrhosis and liver failure. Preterm infants are most susceptible to liver damage.


Recurrent Intrahepatic Cholestasis

Reappearance of cholestasis caused by obstruction within the liver.


Genital rhabdomyoma

A rare benign skeletal muscle neoplasm arising from the female genital tract. It is characterized by the presence of small nucleated rhabdomyoblasts within a fibrous and myxoid stroma.


Benign Skeletal Muscle Neoplasm

A benign mesenchymal neoplasm arising from skeletal muscle tissue.


Extracardiac Rhabdomyoma

A benign mesenchymal neoplasm that shows mature skeletal muscle differentiation.


Central Nervous System Rhabdomyoma

A benign mesenchymal neoplasm arising from the central nervous system.  It consists of mature skeletal muscle tissue.


Intermediate Rhabdomyoma

A morphologic variant of fetal rhabdomyoma characterized by the presence of spindle cell myoblasts and strap-like skeletal muscle cells.


Vulvar Rhabdomyoma

A rare benign polypoid skeletal muscle neoplasm arising from the vulva. It is characterized by the presence of round striated muscle cells and strap-like skeletal muscle cells, and vascular space formations within a fibrous and myxoid stroma.


Fetal rhabdomyoma

A rare benign mesenchymal neoplasm arising from skeletal muscle. It is characterized by the presence of immature spindle and polygonal cells within a scant myxoid stroma. It usually develops in the head and neck region of young children.


Paratesticular Rhabdomyoma

A rhabdomyoma that arises from the paratesticular region.


Vaginal Rhabdomyoma

A rare benign polypoid skeletal muscle neoplasm arising from the vagina.  It is characterized by the presence of round striated muscle cells and strap-like skeletal muscle cells, and vascular space formations within a fibrous and myxoid stroma.


Adult Extracardiac Rhabdomyoma

A benign mesenchymal neoplasm arising from skeletal muscle and occurring in adults.


Classic Rhabdomyoma

A morphologic variant of fetal rhabdomyoma characterized by the presence of a prominent myxoid stroma and primitive skeletal spindle cells.


Mediastinal Rhabdomyoma

A rare benign skeletal muscle neoplasm arising from the mediastinum.


atrial septal defect 7

Atrial septal defect (ASD) with atrioventricular conduction defects is an extremely rare genetic congenital heart disease characterized by the presence of ASD, mostly of the ostium secundum type, associated with conduction anomalies like atrioventricular block, atrial fibrillation or right bundle branch block.


mesenteric lymphadenitis

Inflammation of the mesenteric lymph nodes.


amyloidosis, primary localized cutaneous, 1

Any primary cutaneous amyloidosis in which the cause of the disease is a mutation in the OSMR gene.


familial primary localized cutaneous amyloidosis


amyloidosis, primary localized cutaneous, 3


amyloidosis, primary localized cutaneous, 2


trihydroxyflavanone

A hydroxyflavanone carrying three hydroxy substituents.


negative regulation of mediator complex assembly

Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly.


Stage IB Fallopian Tube Cancer AJCC v6 and v7

Stage IB includes: T1b, N0, M0.  T1b: Tumor limited to both tubes, without penetrating the serosal surface; no ascites.  N0: No regional lymph node metastasis.  M0: No distant metastasis. (AJCC 6th and 7th eds.)


negative regulation of cardiac muscle cell myoblast differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.


Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP.


thyroid follicle

Discrete, cystlike units of the thyroid gland that are lined with cuboidal epithelium and are filled with a colloid substance, about 30 to each lobule[BTO].


fenestra endochoanalis

Opening on the ventral aspect of the nasal capsule. It contains the apertura nasalis interna.


epaxial region somite 17

The epaxial region of somite 17 derived body wall muscle. The epaxial region is dorsal to the horizontal myoseptum. Kimmel et al, 1995.


Expanding aneurysm

Expansion of aneurysm.


positive regulation of branching morphogenesis of a nerve

Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.


negative regulation of vascular wound healing

Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.


negative regulation of cell adhesion involved in sprouting angiogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in sprouting angiogenesis.


negative regulation of vessel branching

Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.


follicular atrophoderma-basal cell carcinoma


feminization of hermaphroditic germ-line

The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.


masculinization of hermaphroditic germ-line

The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.


hermaphrodite germ-line sex determination

The determination of sex and sexual phenotype in the germ line of a hermaphrodite.


female germ-line sex determination

The determination of sex and sexual phenotype in a female organism's germ line.


Metastatic Malignant Abdominal Neoplasm

A malignant neoplasm that arises from the abdomen and has spread from its original site of growth to another anatomic site.


Advanced Malignant Abdominal Neoplasm

A malignant neoplasm that arises from the abdomen and has spread extensively to other anatomic sites or is no longer responding to treatment.


macula of saccule of membranous labyrinth

The oval neuroepithelial sensory receptor in the anterior wall of the saccule; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies.


anterior macula

Macula that is located in the developing anterior inner ear, and gives rise to the macula utricle. (See Anatomical Atlas entry for sensory patches of the ear by T. Whitfield.).


macula of utricle of membranous labyrinth

The neuroepithelial sensory receptor in the inferolateral wall of the utricle; hair cells of the neuroepithelium support the statoconial membrane and have terminal arborizations of vestibular nerve fibers around their bodies; normally sensitive to linear acceleration in the longitudinal axis of the body and to gravitational influences.


macula neglecta

Macula positioned on the floor of the utricle adjacent to the utriculosaccular foramen at the base of the common crus.


posterior macula

Macula that is located in the developing posterior inner ear, and gives rise to the macula neglecta and the macula saccule. (See Anatomical Atlas entry for sensory patches of the ear by T. Whitfield.).


Catalysis of the reaction: (Kdo)2-lipid A + 2 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,poly-cis-undecaprenyl phosphate = (beta-L-Ara4N)2-(KDO)2-lipid A + 2 ditrans,polycis-undecaprenyl phosphate.


sick sinus syndrome 2, autosomal dominant

Any sick sinus syndrome in which the cause of the disease is a mutation in the HCN4 gene.


20q11.2 microduplication syndrome

20q11.2 microduplication syndrome is a rare chromosomal anomaly syndrome, due to partial duplication of the long arm of chromosome 20, characterized by psychomotor and developmental delay, moderate intellectual disability, metopic ridging/trigonocephaly, short hands and/or feet and distinctive facial features (epicanthus, hypoplastic supraorbital ridges, horizontal/downslanting palpebral fissures, small nose with depressed nasal bridge and anteverted nostrils, prominent cheeks, retrognathia and small, thick ears). Growth delay and cryptororchidism are often associated features.


TNFSF11 binding

Binding to tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.


chlorophyllase activity

Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.


brachydactyly type E2

Any brachydactyly type E in which the cause of the disease is a mutation in the PTHLH gene.


immunodeficiency 32B

A rare progressive disease that begins as a primary Epstein-Barr virus (EBV) infection. In this type of infection, the body makes too many lymphocytes (lymphoproliferative disease) for a period of more than 6 months duration. Lymphocytes are a type of white blood cell. They are an importantpart ofthe immune system because they help fight off diseases and protect the body from infection byproducing antibodies against viruses or bacteria and regulating immune responses. In CAEBV there are many antibodies againstEBV in the blood.Most people (about 95% of adults) get infected with EBV at some point in their lives, and never have any health problems.However, EBV can cause infectiousmononucleosis and other illnesses, and has a role in various autoimmune diseases and some types of cancer. While most infections occurring during childhood do not cause any symptoms,EBV infection in adolescents or young adults can often result in mononucleosis.After an EBV infection, the virus becomes latent (inactive) in the body, and, in some cases, the virus may reactivate. This does not always cause symptoms, but people with weakened immune systems are more likely to develop symptoms if EBV reactivates.In rare cases, people infected with EBV develop chronic active EBV virus infection(CAEBV) without apparent immunodeficiency. Most cases of CAEBV have been reported from Japan. These patientshave some of the complications found in otherwise-healthy patients with acute EBV infection, but unlike healthy patients, these complications persist and progress. Symptoms of CAEBV most often include fever, liverdysfunction, an enlarged spleen (splenomegaly), swollen lymph nodes (lymphadenopathy), and low numbers of platelets (thrombocytopenia) as well as high EBV-DNA load in the blood. Other features that appear in more than 10% of patients include enlarged liver (hepatomegaly), anemia, hypersensitivity to mosquito bites, rash, oral ulcers, hemophagocytic syndrome, coronary artery aneurysms, liver failure, lymphoma, and interstitial pneumonia. While the cause is yet unknown, researchers have identified defects in T cells or natural killer (NK) cells activity which results in a decreased defense against the EBV in people with CAEBV.It is important to note that the fatigue and malaise from acute infectious mononucleosis (IM)varies from mild symptoms lasting only a few weeks, to more severe symptoms of fatigue that can persist for several months, or even up to a year or more in up to 10% of patients (which may be considered a less severe form of chronicEBV infection). The persistence of fatigue that is seen in some patients after acute IM would lead some people to believe that EBV may also cause cases of chronic fatigue syndrome (CFS). However, no convincing link has been found between EBV and CFS.Hematopoietic stemcell transplantation has shown promise in the treatment of CAEBV.


negative regulation of toll-like receptor 1 signaling pathway

Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


organosulfonic ester

An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid.