Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA.


dihydroxyfluorene dioxygenase activity

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Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid.


mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.


peptidyl-arginine N5-methylation

The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.


movement of group I intron

Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction.


ergothioneine biosynthesis from histidine via hercynylcysteine sulfoxide synthase

A biosynthetic process that results in the formation of ergothioneine from histidine via a set of steps including the hercynylcysteine sulfoxide synthase reaction, which converts N-alpha,N-alpha,N-alpha-trimethyl-L-histidine directly to hercynylcysteine sulfoxide.


sinapate ester biosynthetic process

The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.


D-ribose biosynthetic process

The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).


maintenance of shoot apical meristem identity

The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.


negative regulation of ureter smooth muscle cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.


citrate catabolic process to diacetyl

The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP.


gluconate 2-dehydrogenase (acceptor) activity

Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.


presynaptic active zone disassembly

The disaggregation of a presynaptic active zone into its constituent components.


Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.


head kidney morphogenesis

The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.


Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).


plasmacytoid dendritic cell activation involved in immune response

A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.


detection of mechanical stimulus involved in sensory perception of wind

The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.


geraniol dehydrogenase activity

Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.


glutamate catabolic process via 2-oxoglutarate

The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.


perturbation by symbiont of host microtubule cytoskeleton

The process in which an organism effects a change that impairs the structure or function of the host microtubule cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.


21-deoxycortisol binding

Binding to 21-deoxycortisol.


male pigmentation

Establishment of a pattern of pigment in males.


specification of plant organ axis polarity

The process in which the polarity of a plant organ axis is specified.


primary meristem tissue development

The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.


3-geranylgeranylindole NADPH:oxygen oxidoreductase (10,11-epoxidizing) activity

Catalysis of the reaction: 3-geranylgeranylindole + O2 + NADPH + H+ = 10,11-epoxy-3-geranylgeranylindole + NADP + H2O.


osmoregulated periplasmic glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan.


response to G1 cell size control checkpoint signaling

A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.


Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3.


cellular response to protozoan

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.


negative regulation of kainate selective glutamate receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of the kainate selective glutamate receptor signaling pathway.


methane monooxygenase NADH activity

Catalysis of the reaction: methane + NADH + H+ + O2 = methanol + NAD+ + H2O.


alveolar primary septum development

The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.


hypochord development

The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.


negative regulation of asymmetric cell division

Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.


L-rhamnose isomerase activity

Catalysis of the reaction: L-rhamnose = L-rhamnulose.


4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity

Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.


phosphocreatine metabolic process

The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle.


maintenance of protein complex location

Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.


suppression of host innate immune response

Any process in which a symbiont stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.


5-carbamoylmethyl uridine residue modification

The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA.


dethiobiotin synthase activity

Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO2 = ADP + dethiobiotin + 4 H+ + phosphate.


versiconal hemiacetal acetate esterase activity

Catalyzes the reactions: versiconal hemiacetal acetate + H2O <=> versiconal + acetate, as well as versiconol acetate + H2O <=> versiconol + acetate.


arabinosyltransferase activity

Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor).


vascular endothelial cell response to oscillatory fluid shear stress

Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell.


enzyme-substrate adaptor activity

An adaptor that brings together an enzyme and its substrate. Adaptors recruit the substrate to its enzyme, thus contributing to substrate selection and specificity.


Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.


The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene.


high-affinity L-ornithine transmembrane transporter activity

Enables the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


Catalysis of the reaction: UDP-alpha-D-glucose + 16-alpha-hydroxygypsogenate = 16-alpha-hydroxygypsogenate-28-beta-D-glucoside + UDP.


equatorial microtubule organizing center assembly

The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center.


thylakoid membrane disassembly

The controlled breakdown of the thylakoid membrane in the context of a normal process.


Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.


negative regulation of sulfur utilization

Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization.


negative regulation of compound eye photoreceptor development

Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.


torso signaling pathway

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The series of molecular signals initiated by an extracellular ligand binding to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine <=> scoparone + S-adenosyl-L-homocysteine + H+.


naringenin 3-dioxygenase activity

Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2.


gibberellin 20-oxidase activity

Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones.


homing of group II introns

Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure.


secretory granule maturation

Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling.


negative regulation of vascular associated smooth muscle cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.


endosome membrane tubulation

A membrane tubulation process occurring in an endosome membrane.


Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose.


magnetoreception by sensory perception of mechanical stimulus

The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.


histone H2AK13 ubiquitin ligase activity

Catalysis of the transfer of a ubiquitin molecule to histone 2A at the lysine-13 residue.


appressorium-mediated entry into host

Penetration by a symbiont into a host organism via an appressorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.


metabotropic glycine receptor activity

Combining with glycine and transmitting the signal across the membrane by changing the activity of intracellular G protein signaling.


xylose binding

Binding to the D- or L-enantiomer of xylose.


regulation of inosine transport

Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


inductive mesenchymal to epithelial cell signaling

Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.


accessory nerve formation

The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.


dextransucrase activity

Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1).


pyridoxal phosphate transmembrane transporter activity

Enables the transfer of pyridoxal phosphate from one side of a membrane to the other. Pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.


glutamatergic neuron differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron.


establishment of ommatidial planar polarity

The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.


dorsal vessel heart proper cell fate commitment

The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).


abscisic acid metabolic process

The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.


linolenate delta15 desaturase activity

Catalysis of the reaction: O2 + a lipid linoleoyl group + a reduced electron acceptor <=> 2 H2O + a lipid alpha-linolenoyl group + an oxidized electron acceptor.


sebaceous gland placode formation

The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.


induction of blood coagulation in another organism

Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.


telomerase RNA localization

Any process in which telomerase RNA is transported to, or maintained in, a specific location.


histone H3K9me2 methyltransferase activity

Catalysis of the reaction: N6,N6-dimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6,N6,N6-trimethyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the dimethylated lysine residue at position 9 of histone H3, producing histone H3K9me3.


leucoplast fission

The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.


diarylpropane peroxidase activity

Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O.


mesenchymal stem cell differentiation involved in nephron morphogenesis

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.


cytidine kinase activity

Catalysis of the reaction: ATP + cytidine = ADP + CMP.


Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol.


contractile vacuole localization

The directed movement of the contractile vacuole to a specific location.


prostaglandin H2 endoperoxidase reductase activity

Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate).


Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.


melibiose binding

Binding to melibiose.


flavone biosynthetic process

The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).


pectin binding

Binding to pectin.


arg-arg specific dibasic protein processing

Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein.


D-serine transmembrane transporter activity

Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid.


4-hydroxybenzoate 3-monooxygenase [NADH] activity

Catalysis of the reaction: 4-hydroxybenzoate + H+ + NADH + O2 = 3,4-dihydroxybenzoate + H2O + NAD+.


colon epithelial cell migration

The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.


pancreatic stellate cell proliferation

The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.


negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus

Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.


inositol tetrakisphosphate 3-kinase activity

Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.


sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process

The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-).


cellular response to aluminum ion

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.


induction of synaptic plasticity by chemical substance

The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require.


malonyl-malonyl acyl carrier protein-condensing enzyme activity

Catalysis of the reaction: 2 H+ + 2 a malonyl-[acp] <=> 2 carbon dioxide + an acetoacetyl-[acp] + a holo-[acyl-carrier protein].


positive regulation of progesterone secretion

Any process that activates or increases the frequency, rate or extent of progesterone secretion.


Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde.


interferon-delta production

The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


mannose biosynthetic process

The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.


5-oxovalerate dehydrogenase activity

Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+.


limit dextrinase activity

Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan.


peptide glutaryltransferase activity

Catalysis of the reaction: glutaryl-CoA + L-lysyl-[protein] = CoA + H+ + N6-glutaryl-L-lysyl-[protein].


mannitol 2-dehydrogenase activity

Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.


molting cycle, collagen and cuticulin-based cuticle

The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.


protein-exporting ATPase activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.


Catalysis of the reaction: UDP-alpha-D-glucose + leucodopachrome <=> H+ + cyclo-dopa 5-O-glucoside + UDP.


Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate.


male germ-line cyst encapsulation

Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.


DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates

Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.


2-phenylethylamine receptor activity

Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.


fluorene catabolic process

The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.


complement component C3b receptor activity

Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


glycerol-3-phosphate oxidase activity

Catalysis of the reaction: sn-glycerol 3-phosphate + O2 = glycerone phosphate + H2O2.


negative regulation of cell migration in another organism

Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism.


myrtenal dehydrogenase activity

Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid.


generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.


endosome fission

The process by which early and late endosomes undergo budding and fission reactions that separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.


CAG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a CAG codon.


cell-matrix adhesion involved in tangential migration using cell-cell interactions

The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex.


protein maturation by [4Fe-4S] cluster transfer

The transfer of an assembled 4Fe-4S] cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.


P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

A calcium-transporting P-type ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration.


heat shock-mediated polytene chromosome puffing

The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.


negative regulation of cuticle pigmentation

Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.


histone H3K56 methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 56) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 56). This reaction is the addition of a methyl group to the lysine residue at position 56 of the histone H3 protein.


galactitol biosynthetic process

The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


response to G2 transition size control checkpoint signaling

A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling.


central tolerance induction to self antigen

Tolerance induction in the central lymphoid organs directed at self antigens.


S-linalool synthase activity

Catalysis of the reaction: geranyl diphosphate + H2O = (S)-linalool + diphosphate.


protocatechuate decarboxylase activity

Catalysis of the reaction: 3,4-dihydroxybenzoate + H+ = catechol + CO2.


peptidyl-selenocysteine modification

The modification of peptidyl-selenocysteine.


Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate.


glucosylglycerol metabolic process

The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.


Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.


neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol.


Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP.


negative regulation of chemokinesis

Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis.


cargo adaptor activity

Binding directly to the structural scaffolding elements of a vesicle coat (such as clathrin or COPII), and bridging the membrane, cargo receptor, and membrane deformation machinery.


seed coat development

The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.


citrate CoA-transferase activity

Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.


indole phytoalexin metabolic process

The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response.


hopanoid biosynthetic process

The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.


sexual sporulation

The formation of spores derived from the products of meiosis.


undecaprenyl-diphosphatase activity

Catalysis of the reaction: di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H+ + phosphate.


regulation of meiotic joint molecule formation

Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.


6-deoxy-6-sulfofructose kinase activity

Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP.


The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix.


strigolactone metabolic process

The chemical reactions and pathways involving strigolactone.


positive regulation of artery morphogenesis

Any process that activates or increases the frequency, rate or extent of artery morphogenesis.


D-ribose 5-phosphate:D-sedoheptulose 7-phosphate transaldolase activity

Catalysis of the reaction: sedoheptulose 7-phosphate + D-ribose 5-phosphate <=> D-glycero-D-altro-octulose 8-phosphate + D-erythrose 4-phosphate.


cellular response to cholecystokinin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.


interleukin-20 receptor activity

Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


silicon efflux transmembrane transporter activity

Enables the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.


endoplasmic reticulum-plasma membrane tethering

The attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers.


wing disc morphogenesis

The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.


beta-fructofuranosidase activity

Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.


teichoic acid D-alanylation

The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.


antigen processing and presentation initiated by receptor mediated uptake of antigen

Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.


peptidyl-lysine 4-dioxygenase activity

Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 4-hydroxy-L-lysine + succinate + CO2.


smoothened signaling pathway involved in lung development

The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.


sulfite reductase (ferredoxin) activity

Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.


glycyl-radical enzyme activating activity

Catalyzes the activation of an enzyme by generating an organic free radical on a glycine residue via a homolytic cleavage of S-adenosyl-L-methionine (SAM).


cross-receptor inhibition within G protein-coupled receptor heterodimer

Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.


negative regulation of epithelial tube formation

Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation.


blood vessel endothelial cell delamination

The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.


semi-lunar valve development

The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.


Binding to 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.


ADP-specific glucokinase activity

Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.


regulation of defense response to fungus

Any process that modulates the frequency, rate or extent of defense response to fungus.


Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2.


cellular response to leukotriene B4

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.


negative regulation of placenta blood vessel development

Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development.


chlorophenol 4-monooxygenase activity

Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol.


floral meristem determinacy

The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).


peptidyl-methionine oxidation

The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone.


pentacyclic triterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.


iminodiacetate dehydrogenase activity

Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine.


Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.


cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity

Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O.


rhombomere boundary formation

The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


modification of postsynaptic actin cytoskeleton

Any process that modifies the structure of a postsynaptic actin cytoskeleton.


phthalate 3,4-dioxygenase activity

Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+.


allantoate deiminase activity

Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine.


Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol.


phototaxis

The directed movement of a motile cell or organism in response to light.


Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.


AMP-thymidine kinase activity

Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate.


indole-3-acetaldehyde reductase (NADPH) activity

Catalysis of the reaction: indole-3-ethanol + NADP+ = (indol-3-yl)acetaldehyde + H+ + NADPH.


Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H+ + UDP.


regulation of intermediate mesodermal cell fate determination

Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination.


Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short chain fatty acid residue.


glycerophosphodiester transmembrane transporter activity

Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.


The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.


Catalysis of the reaction: 1-18:2-2-18:2-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:2-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


indole acetic acid carboxyl methyltransferase activity

Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine.


sulfinylpropanyl adenylate synthase

Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H+ + phosphate.


pronephric duct morphogenesis

The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.


Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A.


HNK-1 sulfotransferase activity

Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).


negative regulation of SREBP signaling pathway in response to increased oxygen levels

Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels.


theanine hydrolase activity

Catalysis of the reaction: N(5)-ethyl-L-glutamine + H2O = L-glutamate + ethylamine.


negative regulation of ERBB4 signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of ERBB4 signaling pathway.


positive regulation of female pigmentation

Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.


regulation of macrophage proliferation

Any process that modulates the frequency, rate or extent of macrophage proliferation.


erythrocyte clearance

The selective elimination of erythrocytes from the body by autoregulatory mechanisms.


glucosinolate metabolic process

The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.


regulation of response to cell cycle checkpoint signaling

Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling.


endoplasmic reticulum membrane biogenesis

The process in which an endoplasmic reticulum membrane is synthesized, aggregates, and bonds together.


positive regulation of response to G1 DNA damage checkpoint signaling

Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.


positive regulation of chromosome attachment to the nuclear envelope

Any process that activates or increases the frequency, rate or extent of the chromosome attachment to the nuclear envelope.


soyasapogenol B UDP-glucosyl transferase activity

Catalysis of the reaction: UDP-alpha-D-glucose(2-) + soyasapogenol B <=> UDP(3-) + a soyasapogenol B monoglucoside.


positive regulation of defense response to oomycetes

Any process that activates or increases the frequency, rate or extent of defense response to oomycetes.


lectin-induced modified bacterial internalization

The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by secretion of lectins which bind to the bacterial surface. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.


regulation of transcytosis

Any process that modulates the frequency, rate or extent of transcytosis.


negative regulation of renal albumin absorption

Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption.


capsorubin synthase activity

Catalysis of the reaction: violaxanthin = capsorubin.


regulation of renal amino acid absorption

Any process that modulates the frequency, rate or extent of renal amino acid absorption.


planar cell polarity pathway involved in axon guidance

Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance.


cell adhesion involved in single-species biofilm formation

The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.


cellular modified histidine biosynthetic process

The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.


positive regulation of conidiophore development

Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.


hexulose-6-phosphate isomerase activity

Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate.


oligosaccharide transmembrane transporter activity

Enables the transfer of oligosaccharide from one side of a membrane to the other.


Catalysis of the reaction: H+ + tetrahydrogeranylgeranyl-PP + NADPH = (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + NADP.


response to vitamin B2

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.


intrachromosomal DNA recombination

The process of DNA recombination occurring within a single chromosome.


regulation of axial mesodermal cell fate specification

Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.


polyphosphate kinase activity

Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).


phytoceramidase activity

Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.


rRNA endonuclease activity

Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.


spermine acetylation

The modification of spermine by addition of acetyl groups.


positive regulation of plasmacytoid dendritic cell antigen processing and presentation

Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.


methanesulfonic acid metabolic process

The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide.


mesonephric mesenchymal cell differentiation

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.


type III interferon receptor activity

Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.


long-chain fatty acid luciferin component ligase activity

Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with an aliphatic tail of 13 to 21 carbons.


Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.


regulation of non-professional antigen presenting cell antigen processing and presentation

Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.


Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP.


positive regulation of pentose catabolic process to ethanol

Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol.


vasoconstriction by vasopressin involved in systemic arterial blood pressure control

The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream.


biotin transmembrane transporter activity

Enables the transfer of biotin from one side of a membrane to the other. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.


tRNA 4-thiouridine biosynthesis

The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.


cellular response to diethyl maleate

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.


histone H2B C-terminal K residue ubiquitin ligase activity

Catalysis of the transfer of a ubiquitin molecule to a histone 2B at the conserved C-terminal lysine (K) residue. The last K residue is at position 119 in fission yeast, 123 in budding yeast, and 120 in mammals.


methionine S-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine.


regulation of octopamine or tyramine signaling pathway

Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway.


negative regulation of ribonucleoprotein complex localization

Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization.


mini excitatory postsynaptic potential

A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.


Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate.


photoreceptor cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.


Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP.


phenyllactate dehydrogenase activity

Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH.


intermicrovillar adhesion

The cell-cell adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.


1-methyladenosine nucleosidase activity

Catalysis of the reaction: 1-methyladenosine + H2O = 1-methyladenine + ribofuranose.


abaxial cell fate specification

The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


histone glutaryltransferase activity

Catalysis of the reaction: glutaryl-CoA + histone = CoA + H+ + N6-glutaryl-histone.


negative regulation of potassium:proton exchanging ATPase activity

Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.


cordyol C metabolic process

The chemical reactions and pathways involving cordyol C.


poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.


site-specific DNA-methyltransferase (cytosine-N4-specific) activity

Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.


long-chain fatty-acyl-glutamate deacylase activity

Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate.


negative regulation of sensory perception of pain

Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain.


ventral cochlear nucleus development

The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.


Catalysis of the reaction: indole-3-acetate + L-phenylalanine + ATP = H+ + indole-3-acetyl-phenylalanine + AMP + diphosphoric acid.


stizolobinate synthase activity

Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.


endo-beta-bergamotene synthase activity

Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid.


Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H+.


negative regulation of monocyte aggregation

Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation.


ventricular zone cell fate commitment

The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.


negative regulation of non-professional antigen presenting cell antigen processing and presentation

Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.


peptidyl-lysine deglycation

The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.


6-phospho-beta-glucosidase activity

Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.


phenylacetate catabolic process

The chemical reactions and pathways resulting in the breakdown of phenylacetate.


circadian regulation of calcium ion oscillation

Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours.


fear-induced aggressive behavior

Aggressive behavior associated with attempts to flee from a threat.


Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.


hypoglossal nucleus development

The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.


negative regulation of mitotic DNA damage checkpoint

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.


Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.


regulation of trophectodermal cell proliferation

Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation.


detection of temperature stimulus involved in thermoception

The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.


D-mannose 6-phosphate 1-epimerase activity

Catalysis of the reaction: alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate.


stamen development

The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.


Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + H+ + NADPH.


Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine.


hypoxanthine DNA N-glycosylase activity

DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine).


c-di-GMP signaling

Any process that mediates the transfer of information from one cell to another using c-di-GMP as the signal.


nicotianamine synthase activity

Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H+ + nicotianamine.


indolebutyric acid metabolic process

The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants.


metanephric glomerular mesangial cell fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.


formation of haustorium for nutrient acquisition

The assembly of a haustorium, a projection from a symbiotic cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.


glycerone kinase activity

Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H+.


high-affinity nickel cation transmembrane transporter activity

Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.


curli assembly

The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex.


purine nucleoside interconversion

The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.


sarcosine dehydrogenase activity

Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein.


trans-synaptic signaling by trans-synaptic complex

Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.


6-hydroxycineole catabolic process

The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.


chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration

The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb.


sorbose metabolic process

The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.


Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O.


cilium disassembly

A cellular process that results in the breakdown of a cilium.


C-X3-C chemokine receptor activity

Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.


t-SNARE clustering

The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies.


histone H3 arginine deiminase activity

Catalysis of the reaction: H2O + histone H3 L-arginyl = histone H3 L-citrullyl + NH4+, resulting in histone H3 citrullination.


regulation of activated CD8-positive, alpha-beta T cell apoptotic process

Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.


high density lipoprotein particle mediated signaling

The series of molecular signals mediated by the detection of high density lipoprotein particle.


glyceryl-ether monooxygenase activity

Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine).


regulation of central tolerance induction

Any process that modulates the frequency, rate, or extent of central tolerance induction.


perception of static position

The perception of the orientation of different parts of the body with respect to one another.


fructose uniporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).


glutamate-tRNA(Gln) ligase activity

Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP.


pyruvate dehydrogenase (NADP+) activity

Catalysis of the reaction: CoA + NADP+ + pyruvate = acetyl-CoA + CO2 + NADPH.


vibriobactin metabolic process

The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae.


Catalysis of the reaction: 3,5-dimethoxyphenol + S-adenosyl-L-methionine = H+ + 1,3,5-trimethoxybenzene + S-adenosyl-L-homocysteine.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).


venous endothelial cell migration involved in lymph vessel development

The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.


myoblast fate commitment in head

The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.


cellular response to auxin stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.


arachidonic acid 11,12-epoxygenase activity

Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid.


xylan catabolic process

The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.


L-glyceraldehyde 3-phosphate reductase activity

Catalysis of the reaction: sn-glycerol 3-phosphate + NADP = H+ + L-glyceraldehyde 3-phosphate + NADPH.


primary follicle stage

The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.


aldose sugar dehydrogenase activity

Catalysis of the reaction: H2O + an aldose + an oxidized electron acceptor = H+ + an aldonate + a reduced electron acceptor.


follicle-stimulating hormone receptor activity

Combining with follicle-stimulating hormone to initiate a change in cell activity.


substance K receptor activity

Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity.


protein insertion into mitochondrial inner membrane from matrix

The process in which a protein is incorporated into the mitochondrial inner membrane from the matrix side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.


UAG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UAG codon.


anterior lateral line nerve glial cell development

The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


perturbation of platelet aggregation in another organism

The process in which an organism effects a change that affects platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.


Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H+ + O2 = N-acetylanthranilate + CO.


compound eye cone cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.


S-alkylcysteine lyase activity

Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate.


positive regulation of vascular associated smooth muscle cell migration

Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.


ferredoxin-NADP+ reductase activity

Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+.


salicylate 5-hydroxylase activity

Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+.


specification of pronephric tubule identity

The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.


D-arabinokinase activity

Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.


muramyl dipeptide binding

Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.


4-aminobenzoate amino acid synthetase activity

Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate.


protopine 6-monooxygenase activity

Catalysis of the reaction: H+ + NADPH + O2 + protopine = 6-hydroxyprotopine + H2O + NADP+.


positive regulation of cell communication

Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.


neuron development

The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


3-aminopropanal dehydrogenase activity

Catalysis of the reaction: 3-ammoniopropanal + NAD + H2O <=> 2 H+ + beta-alanine + NADH.


cellular response to interleukin-11

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.


limb spinous cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.


regulation of water channel activity

Any process that modulates the frequency, rate or extent of water channel activity.


base-excision repair, AP site formation via deaminated base removal

A base-excision repair, AP site formation process occurring via excision of a deaminated base.


positive regulation of nuclear migration along microtubule

Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.


reproductive senescence

A life cycle stage during which the reproductive capacity and fitness of an organism declines.


acetate:monoatomic cation symporter activity

Enables the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).


3-hydroxyphenyl propanoate transmembrane transporter activity

Enables the transfer of 3-hydroxyphenyl propanoate from one side of a membrane to the other.


thymidine phosphorylase activity

Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.


Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O.


pronuclear fusion

The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.


cysteate synthase activity

Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-.


smoothened signaling pathway involved in growth plate cartilage chondrocyte development

The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time.


Catalysis of the reaction: 1-18:2-2-18:3-digalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-18:3-digalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


positive regulation of foraging behavior

Any process that activates or increases the frequency, rate or extent of foraging behavior.


petal vascular tissue pattern formation

Vascular tissue pattern formation as it occurs in the petal of vascular plants.


negative regulation of ERK5 cascade

Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.


delta-cuprenene synthase activity

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> delta-cuprenene + diphosphoric acid.


cephalosporin C metabolic process

The chemical reactions and pathways involving cephalosporin C.


long-chain fatty-acyl-CoA catabolic process

The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.


regulation of cellular response to glucose starvation

Any process that modulates the frequency, rate or extent of cellular response to glucose starvation.


intrinsic apoptotic signaling pathway in response to nitrosative stress

The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.


Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.


L-arabinose 1-dehydrogenase (NAD+) activity

Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.


negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus

Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.


central nervous system control of baroreceptor feedback

The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.


acetyl-CoA biosynthetic process from pantothenate

The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA.


sterigmatocystin catabolic process

The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.


mannan catabolic process

The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.


prebend segment development

The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.


anatomical structure development

The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.


oocyte fate commitment

The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.


Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide.


regulation of calcium-dependent ATPase activity

Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity.


enzyme-directed rRNA pseudouridine synthesis

The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.


behavioral response to water deprivation

Any process that results in a change in the behavior of an organism as a result of deprivation of water.


stearic acid binding

Binding to stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.


limonene 8-hydratase activity

Catalysis of the reaction: limonene + H2O = alpha-terpineol.


acetoacetate-CoA ligase activity

Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H+.


response to pyrimidine ribonucleotide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrimidine ribonucleotide stimulus.


RNA NAD-cap (NAD-forming) hydrolase activity

Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + H+ + NAD+.


negative regulation of pectin catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process.


protein-heme linkage

The covalent linkage of heme and a protein.


decylhomocitrate synthase activity

Catalysis of the reaction: 2-oxoglutarate + H2O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H+.


hydroxymethylglutaryl-CoA reductase (NADPH) activity

Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH.


regulation of granulosa cell apoptotic process

Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.


negative regulation of lung blood pressure

The process that decreases the force with which blood travels through the lungs.


response to menaquinone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.


light-driven active monoatomic ion transmembrane transporter activity

Active transport of an ion across a membrane, driven by light.


cytotoxic T cell differentiation

The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.


negative regulation of hepatocyte growth factor receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.


neural rod formation

The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.


positive regulation of cyclodextrin catabolic process

Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process.


establishment of dense core granule localization

The directed movement of a dense core granule to a specific location.


3',2'-cyclic GMP-AMP synthase activity

Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic G-P(3'-5')A-P(2'-5') (cyclic 3',2' GAMP).


compound eye retinal cell programmed cell death

Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.


long-chain-alcohol oxidase activity

Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.


Schwann cell migration

The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.


small molecule binding

Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule.


reorganization of cellular membranes to establish viral sites of replication

A process in intracellular membranes are reorganized by viral proteins that perturb membrane integrity and can cause an extensive rearrangement of cellular membranes, forming membranous webs, which are thought to be the site of replication or certain viruses, for example the HPV virus.


acylpyruvate hydrolase activity

Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.


AGC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an AGC codon.


7-dehydrocholesterol reductase activity

Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+.


response to ultrasound

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.


exo-oligoalginate lyase activity

Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.


glycine catabolic process to creatine

The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine.


formation of extrachromosomal circular DNA

Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.


chrysanthemyl diphosphate synthase activity

Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.


IAA-Ala conjugate hydrolase activity

Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.


1,6-alpha-L-fucosidase activity

Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.


positive regulation of tolerance induction to self antigen

Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.


propionate CoA-transferase activity

Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.


protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine

The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine.


ether catabolic process

The chemical reactions and pathways resulting in the breakdown of ether.


vesicle scission

The membrane scission process that is the final step in the formation of a vesicle, leading to separation from its parent membrane. Vesicle scission involves the constriction of a neck-forming protein complex, consisting e.g. of dynamin, around the budded membrane, leading to vesicle closure during its separation from the parent membrane.


nonadec-1-ene metabolic process

The chemical reactions and pathways involving nonadec-1-ene.


Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.


cellular response to interleukin-15

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.


molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)

The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).


Catalysis of the reaction: 3-hydroxyanthranilate + O2 = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H+.


rubredoxin-NAD(P)+ reductase activity

Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.


host response to induction by symbiont of tumor, nodule or growth in host

Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.


positive regulation of neuroinflammatory response

Any process that activates or increases the frequency, rate or extent of neuroinflammatory response.


neural fold elevation formation

The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.


regulation of fungal-type cell wall biogenesis

Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.


positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization

Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.


positive regulation of secondary cell wall biogenesis

Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.


pseurotin A catabolic process

The chemical reactions and pathways resulting in the breakdown of pseurotin A.


negative regulation of small intestinal transit

Any process that decreases the frequency, rate or extent of any small intestinal transit process, the migration of ingested material along the length of the small intestine.


Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.


Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor.


negative regulation of acrosome reaction

Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction.


oligoribonucleotidase activity

Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.


geraniol biosynthetic process

The chemical reactions and pathways resulting in the formation of geraniol.


dethiobiotin binding

Binding to dethiobiotin.


neural crest cell differentiation involved in parathyroid gland development

Any neural crest cell differentiation that is involved in parathyroid gland development.


inositol hexakisphosphate binding

Binding to inositol hexakisphosphate.


Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).


envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism.


o-pyrocatechuate decarboxylase activity

Catalysis of the reaction: 2,3-dihydroxybenzoate + H+ = catechol + CO2.


fungal-type cell wall (1->3)-alpha-glucan biosynthetic process

The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.


glial cell projection elongation involved in axon ensheathment

The extension of a glial cell process or projection to wrap around an axon.


detection of hypoxic conditions in blood by chemoreceptor signaling

The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.


trans-synaptic signaling by endocannabinoid

Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.


negative regulation of mitotic cytokinetic process

Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process.


mitochondrion DNA recombination

Any DNA recombination that takes place in mitochondrion.


positive regulation of (R)-carnitine transmembrane transport

Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport.


(S)-scoulerine biosynthetic process

The chemical reactions and pathways resulting in the formation of (S)-scoulerine.


Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H+ + NADPH + O2 = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H2O + NADP+. (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.


Catalysis of the reaction: O2 + reduced [NADPH--hemoprotein reductase] + testosterone = 16beta,17beta-dihydroxyandrost-4-en-3-one + H+ + H2O + oxidized [NADPH--hemoprotein reductase].


COPII receptor activity

Binding specifically to a substance (cargo) to deliver it to a COPII transport vesicle. Cargo receptors span a membrane (either the plasma membrane or a vesicle membrane), binding simultaneously to cargo molecules and coat adaptors, to efficiently recruit soluble proteins to nascent vesicles.


response to ziprasidone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.


positive regulation of neuromuscular synaptic transmission

Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.


high-affinity IgG receptor activity

Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + benzyladenine-7-N-glucoside + UDP.


regulation of sporangium germination

Any process that modulates the frequency, rate or extent of sporangium germination.


lateral line nerve glial cell development

The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.


salicylaldehyde dehydrogenase activity

Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.


peptide pheromone maturation

The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae.


negative regulation of pyloric antrum smooth muscle contraction

Any process that decreases the frequency, rate or extent of any pyloric antrum smooth muscle contraction.


pyocyanin hydroxylase activity

Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ = pyocyanin + NAD + carbon dioxide + H2O.


Catalysis of the reaction: N-benzyloxycarbonylglycine + H2O + H+ = benzyl alcohol + CO2 + glycine.


Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine.


VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway

The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


iodide peroxidase activity

Catalysis of the reaction: iodide + H2O2 = iodine + 2 H2O.


tRNA dimethylallyltransferase activity

Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.


interleukin-21 receptor activity

Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


L-fucose biosynthetic process

The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).


lysine biosynthetic process via diaminopimelate

The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.


indole-3-acetaldehyde reductase (NADH) activity

Catalysis of the reaction: indole-3-ethanol + NAD+ = (indol-3-yl)acetaldehyde + H+ + NADH.


luteinizing hormone signaling pathway involved in ovarian follicle development

The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.


fosfomycin 2-glutathione ligase activity

Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.


indoleacetic acid ester conjugate biosynthetic process

The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.


alpha-pinene metabolic process

The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.


dimethylallylcistransferase activity

Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.


activation of plasma proteins involved in acute inflammatory response

Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.


skeletal muscle satellite cell fate specification

The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.


guanidinoacetate kinase activity

Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H+ + phosphoguanidinoacetate.


calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration

Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.


cellular response to prostaglandin I stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.


endocardial cushion to mesenchymal transition involved in heart chamber septation

A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum.


peptidyl-lysine palmitoylation

The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.


all-trans-neoxanthin metabolic process

The chemical reactions and pathways involving all-trans-neoxanthin.


cellular response to chondroitin 4'-sulfate

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.


regulation of cuticle pigmentation

Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.


pro-T cell lineage commitment

The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.


regulation of glucomannan catabolic process

Any process that modulates the frequency, rate or extent of glucomannan catabolic process.


AV node cell-bundle of His cell adhesion involved in cell communication

The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.


5-fluorocytosine deaminase activity

Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium.


protein localization to P-body

Any process in which a protein is transported to, or maintained at, a P-body.


The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.


epistomal sclerite morphogenesis

The process in which the anatomical structures of the epistomal sclerite are generated and organized.


positive regulation of renal amino acid absorption

Any process that activates or increases the frequency, rate or extent of renal amino acid absorption.


actin filament bundle convergence

A process of actin filament bundle distribution that results in the compaction of actin filaments.


purine nucleotide-sugar transmembrane transporter activity

Enables the transfer of a purine nucleotide-sugar from one side of a membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.


CoA-disulfide reductase (NADP) activity

Catalysis of the reaction: 2 CoA + NADP+ = CoA-disulfide + NADPH + H+.


rhombomere 6 formation

The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.


galactitol transmembrane transporter activity

Enables the transfer of a galactitol from one side of a membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.


negative regulation of type B pancreatic cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.


cellulose metabolic process

The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.


uracilylalanine synthase activity

Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.


positive regulation of adaptive immune effector response

Any process that activates or increases the frequency, rate or extent of adaptive immune effector response.


cellular detoxification of cadmium ion

Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.


oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen.


gerfelin catabolic process

The chemical reactions and pathways resulting in the breakdown of gerfelin.


Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H+.


D-allose-importing ATPase activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in).


establishment of endoplasmic reticulum localization to postsynapse

The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.


retrograde trans-synaptic signaling by lipid

Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.


biofilm matrix assembly

A process that results in the assembly of a biofilm matrix.


positive regulation of cardiac muscle myoblast proliferation

Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation.


cADPR-sensitive calcium-release channel activity

Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.


GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine

The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.


multi-species biofilm formation

A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.


regulation of D-aspartate import across plasma membrane

Any process that modulates the frequency, rate or extent of the directed import of D-aspartate from the extracellular region across the plasma membrane and into the cytosol.


cellular response to raffinose

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.


cellular response to L-ascorbic acid

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.


plastid translation

The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.


thiamine binding

Binding to thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.


endothelial cell activation involved in immune response

A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.


dextrin alpha-glucosidase activity

Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.


2-octaprenylphenol hydroxylase activity

Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O.