actin phosphorylation

The transfer of one or more phosphate groups to an actin molecule.


perturbation of host receptor-mediated signal transduction

biolink:BiologicalProcess biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

A process in which a symbiont alters or subverts a receptor-mediated signal transduction pathway in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


choline monooxygenase activity

biolink:MolecularActivity biolink:BiologicalProcessOrActivity biolink:BiologicalEntity biolink:NamedThing biolink:Occurrent biolink:OntologyClass biolink:ThingWithTaxon biolink:PhysicalEssenceOrOccurrent

Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.


lincomycin metabolic process

The chemical reactions and pathways involving lincomycin.


regulation of natural killer cell apoptotic process

Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.


response to cholecystokinin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholecystokinin stimulus.


mitochondrial respirasome assembly

The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, complex II, complex III, complex IV) to form a large supercomplex.


galactose catabolic process via D-galactonate

The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.


putamen development

The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.


cellular response to chemical stress

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress.


N-terminal peptidyl-alanine acetylation

The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase.


positive regulation of positive chemotaxis to cAMP by DIF-1

Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.


negative regulation of cardiac ventricle development

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development.


posterior lateral line ganglion development

The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.


cardiac endothelial to mesenchymal transition

A transition where a cardiac endothelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Endocardial cells (specialized endothelial cells that line the heart) undergo EndMT, and give rise to mesenchymal cells necessary for proper heart development. EndMT, specifically generates valve progenitor cells that give rise to the mitral and tricuspid valves. EndMT also contributes to endocardial cushion formation, as well as to generation of cardiac fibroblasts and smooth muscle cells, but not cardiac myocytes.


envenomation resulting in modulation of voltage-gated sodium channel activity in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism.


Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.


COPI coating of Golgi vesicle, inter-Golgi cisterna

The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.


pantothenate catabolic process

The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.


aspartate-ammonia ligase (ADP-forming) activity

Catalysis of the reaction: L-aspartate + ATP + NH4 = L-asparagine + ADP + 2 H+ + phosphate.


artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure

An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.


Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.


response to interleukin-32

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.


p-xylene metabolic process

The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.


Catalysis of the reaction: H+ + dihydrogeranylgeranyl-PP + NADPH = tetrahydrogeranylgeranyl-PP + NADP.


positive regulation of establishment of blood-brain barrier

Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.


regulation of estrone secretion

Any process that modulates the frequency, rate or extent of estrone secretion.


asexual spore wall assembly

The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species.


Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H+ + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.


cellular component assembly

The aggregation, arrangement and bonding together of a cellular component.


negative regulation of epithelium regeneration

Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration.


oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.


Catalysis of the reaction: malonyl-CoA + 3 H+ + a heptodecanoyl-[acp] = octadec-1-ene + 2 carbon dioxide + coenzyme A + a holo-[acyl-carrier protein].


positive regulation of cuticle pigmentation

Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.


sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity

Catalysis of the reaction: O2 + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H2O.


paranodal junction maintenance

The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.


lipopolysaccharide localization to cell outer membrane

A process in which a lipopolysaccharide is transported to the cell outer membrane.


regulation of border follicle cell delamination

Any process that regulates the frequency, rate or extent of border cell delamination.


negative regulation of mesonephric glomerular mesangial cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.


regulation of amniotic stem cell differentiation

Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation.


negative regulation of oligodendrocyte apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process.


Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose.


histone H3K9 monomethyltransferase activity

Catalysis of the reaction: L-lysyl9-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl9-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a methyl group to the unmethylated lysine residue at position 9 of histone H3, producing histone H3K9me.


Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H+ = CO2 + pantetheine 4'-phosphate.


myocardial epithelial involution involved in heart jogging

The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging.


roof plate formation

The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.


Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (3S)-(+)-asterisca-2(9),6-diene.


dendrite development by retrograde extension

The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point.


tubulin N-acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine.


response to continuous far red light stimulus by the high-irradiance response system

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.


protein-containing complex organization

Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.


positive regulation of acetylcholine biosynthetic process

Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process.


gamma-aminobutyrate transaminase (glyoxylate dependent) activity

Catalysis of the reaction: gamma-aminobutyric acid + 2-oxo monocarboxylic acid anion = 4-oxobutanoate + glycine.


negative regulation of mannan catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process.


miltiradiene catabolic process

The chemical reactions and pathways resulting in the breakdown of miltiradiene.


histone H4K20 trimethyltransferase activity

Catalysis of the reaction: L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-methionine = 3 H+ + N(6),N(6),N(6)-trimethyl-L-lysyl(20)-[histone H4] + 3 S-adenosyl-L-homocysteine. This reaction is the addition of three methyl groups to the lysine residue at position 20 of the histone H4 protein, producing histone H4K20me3.


Catalysis of the reaction:(4S)-4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.


negative regulation of T-helper 17 cell extravasation

Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation.


tyrosine decarboxylase activity

Catalysis of the reaction: L-tyrosine = tyramine + CO2.


opine dehydrogenase activity

Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H2O + NAD+ = L-2-aminopentanoate + H+ + NADH + pyruvate.


glycosinolate biosynthetic process

The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


cellular detoxification of aldehyde

Any process carried out at the cellular level that reduces or removes the toxicity of an aldehyde. These may include transport of aldehydes away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


male germline ring canal formation

Formation of the intercellular bridges that connect the germ-line cells of a male cyst.


peptidylamidoglycolate lyase activity

Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.


lithocholic acid receptor activity

Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity.


uracil:monoatomic cation symporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).


negative regulation of terminal cell fate specification, open tracheal system

Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.


regulation of cytokinin dehydrogenase activity

Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity.


C-C motif chemokine 5 receptor activity

Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


cspyrone B1 metabolic process

The chemical reactions and pathways involving cspyrone B1.


Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,10E,12R,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.


positive regulation of short-term synaptic potentiation

Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation.


establishment of plastid localization

The directed movement of a plastid to a specific location in the cell.


allatostatin receptor activity

Combining with allatostatin to initiate a change in cell activity.


peptidyl-phenylalanine modification

The modification of peptidyl-phenylalanine.


alpha-glucan catabolic process involved in ascospore release from ascus

The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus.


positive regulation of cleistothecium development

Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.


cis-zeatin biosynthetic process

The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.


Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.


ATPase-coupled polar amino acid-transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).


Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-.


zeaxanthin epoxidase activity

Catalysis of the reaction: all-trans-zeaxanthin + 4 H+ + 2 O2 + 4 reduced [2Fe-2S]-[ferredoxin] = all-trans-violaxanthin + 2 H2O + 4 oxidized [2Fe-2S]-[ferredoxin].


negative regulation of neuronal action potential

Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.


gibberellic acid mediated signaling pathway, G-alpha-dependent

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The series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.


Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H+.


dCTP deaminase (dUMP-forming) activity

Catalysis of the reaction: dCTP + 2 H2O = diphosphate + dUMP + H+ + NH4.


IP-10 production

The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


90S preribosome assembly

The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.


The series of molecular signals initiated by interleukin-9 binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


positive regulation of toll-like receptor 1 signaling pathway

Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.


regulation of pyrroline-5-carboxylate reductase activity

Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.


pyruvate, phosphate dikinase activity

Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H+ + phosphoenolpyruvate.


electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity

Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II.


D-glutamine metabolic process

The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid.


Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.


vascular associated smooth muscle cell fate determination

The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.


positive regulation of glycerol transport

Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.


Catalysis of the reaction: benzoate + L-glutamate + ATP <=> H+ + N-benzoyl-L-glutamate + AMP + diphosphoric acid.


regulation of invasive growth in response to glucose limitation

Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation.


sphingolipid floppase activity

Catalysis of the movement of a sphingolipid from the cytosolic to the exoplasmic leaftlet of a membrane, using energy from the hydrolysis of ATP.


emericellamide A metabolic process

The chemical reactions and pathways involving emericellamide A.


Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol.


interleukin-30 production

The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


Catalysis of the reaction: UDP-alpha-D-glucose + kaempferol 3-O-glucoside <=> kaempferol 3,7-O-diglucoside + UDP.


sedoheptulokinase activity

Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H+ + sedoheptulose 7-phosphate.


Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid.


protein palmitoleylation

The covalent attachment of a palmitoleyl group to a protein.


coenzyme B metabolic process

The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.


histone H2AR3 arginine deiminase activity

Catalysis of the reaction: H2O + histone 2A L-arginyl (position 3)= histone 2A L-citrullyl (position 3) + NH4+, resulting in histone H2A citrullination at position 3.


positive regulation of inner ear receptor cell differentiation

Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.


negative regulation of cell proliferation in midbrain

Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain.


negative regulation of dipeptide transport

Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport.


Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O2 = CO2 + dehydroascorbate + ethylene + 2 H2O + hydrogen cyanide. Ethene is also known as ethylene.


5.8S rRNA binding

Binding to 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.


RNA polymerase III preinitiation complex assembly

The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter.


Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.


disruption by symbiont of host mitochondrion

The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.


zinc efflux active transmembrane transporter activity

Enables the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force.


anandamide 8,9 epoxidase activity

Catalysis of the reaction: N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine + O2 + reduced [NADPH--hemoprotein reductase] = H+ + H2O + N-(8,9-epoxy-5Z,11Z,14Z-eicosatrienoyl)-ethanolamine + oxidized [NADPH--hemoprotein reductase].


Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA.


branch fusion, open tracheal system

Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.


soladodine glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+.


negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.


prenol catabolic process

The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.


citramalate CoA-transferase activity

Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.


Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule.


synaptic vesicle budding from presynaptic endocytic zone membrane

Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle.


cell morphogenesis

The developmental process in which the size or shape of a cell is generated and organized.


kievitone hydratase activity

Catalysis of the reaction: kievitone hydrate = H2O + H+ + kievitone.


negative regulation of maltotetraose transport

Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport.


Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O.


alpha-amyrin 28-monooxygenase activity

Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O.


m-xylene metabolic process

The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.


regulation of calcitonin secretion

Any process that modulates the frequency, rate or extent of calcitonin secretion.


GMP synthase activity

Catalysis of the reaction: ATP + XMP + NH4(+) = AMP + diphosphate + GMP + 2H+.


protein deglycation

The removal of a sugar or dicarbonyl from a glycated protein.


benzoin aldolase activity

Catalysis of the reaction: benzoin = 2 benzaldehyde.


pronephros maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.


cellular response to cortisone stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.


UGC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UGC codon.


ionotropic sweet taste receptor activity

Enables the transmembrane transfer of an ion by a channel that opens when a specific soluble sweet compound has been bound by the channel complex or one of its constituent parts.


Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline.


positive regulation of mast cell differentiation

Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.


wing disc proximal/distal pattern formation

The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing.


macrophage inflammatory protein-1 gamma production

The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


epidermal growth factor receptor signaling pathway involved in heart process

Any epidermal growth factor receptor signaling pathway that is involved in heart process.


positive regulation of Hulle cell development

Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


negative regulation of positive chemotaxis to cAMP

Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.


induction by virus of host apoptotic process

Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process.


aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway

The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.


Catalysis of the reaction: H+ + orotidine 5'-phosphate = CO2 + UMP.


negative regulation of chitin-based cuticle tanning

Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning.


IMP catabolic process

The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate.


campestanol hydroxylase activity

Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP.


Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.


enterobactin transmembrane transporter activity

Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine from one side of a membrane to the other.


4-nitrobenzyl alcohol oxidase activity

Catalysis of the reaction: 4-nitrobenzyl alcohol + O2 <=> 4-nitrobenzaldehyde + hydrogen peroxide.


beta-amyrin 11-oxidase activity

Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP.


ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity

Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP.


trigeminal ganglion structural organization

The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.


lipid-linked peptidoglycan transporter activity

Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.


Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine.


protein localization to cleavage furrow rim

A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim.


ascopyrone tautomerase activity

Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.


UUA codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UUA codon.


negative regulation of ergot alkaloid biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process.


oocyte nucleus localization involved in oocyte dorsal/ventral axis specification

The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte.


melanin catabolic process

The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.


Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O2 = carnitine + CO2 + succinate.


renal urate salt excretion

The elimination of urate salt or uric acid from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.


modulation by host of viral RNA genome replication

A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication.


radial microtubular system formation

Formation of radial microtubular systems during male meiotic cytokinesis in plants.


asparagine biosynthetic process from cysteine

The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine.


mesonephric macula densa development

The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.


4-nitrotoluene monooxygenase activity

Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O.


propionate metabolic process, methylmalonyl pathway

The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway.


Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.


sorocarp development

The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.


colanic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.


Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.


furaneol oxidoreductase activity

Catalysis of the reaction: 4-hydroxy-2,5-dimethylfuran-3-one + NADP <=> 4-hydroxy-5-methyl-2-methylenefuran-3-one + NADPH + H+.


NAD+ nucleotidase, cyclic ADP-ribose generating

Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity.


mRNA guanylyltransferase activity

Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.


Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate.


metanephric glomerular parietal epithelial cell development

The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.


positive regulation of viral translation

Any process that activates or increases the frequency, rate or extent of viral translation.


pancreatic PP cell development

The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.


Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.


hypophysis formation

The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.


macrophage migration inhibitory factor production

The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


regulation of cellobiose metabolic process

Any process that modulates the frequency, rate or extent of cellobiose metabolic process.


sulfide oxidation, using sulfur dioxygenase

A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase.


alpha-1,3-glucan synthase activity

Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.


ventriculo bulbo valve morphogenesis

The process in which the structure of the ventriculo bulbo valve is generated and organized.


response to propan-1-ol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus.


serine decarboxylase activity

Catalysis of the reaction: H+ + L-serine <=> ethanolaminium(1+) + carbon dioxide.


sensory perception of low humidity

The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.


cellular response to biotin starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.


ligand-gated calcium channel activity

Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.


prolactin receptor activity

Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


basophil chemotaxis

The movement of a basophil in response to an external stimulus.


ceramidase activity

Catalysis of the reaction: H2O + a ceramide = a sphingoid base + a fatty acid.


Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide.


NMDA selective glutamate receptor signaling pathway

The series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex, and ending with the regulation of a downstream cellular process, e.g. transcription.


5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity

Catalysis of the reaction: a 5'-end (N7-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + N7-methyl-GDP + H+.


Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O.


auxin biosynthetic process

The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.


negative regulation of aortic smooth muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation.


positive regulation of cell communication by electrical coupling

Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.


benzene metabolic process

The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.


photoreceptor cell axon guidance

The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.


multivesicular body-lysosome fusion

The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.


Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H+ + NADPH.


protein localization to secretory granule

A process in which a protein is transported to, or maintained in, a location within a secretory granule.


ganglioside GM1 binding

Binding to ganglioside GM1.


cyclohexanone monooxygenase activity

Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.


fonsecin metabolic process

The chemical reactions and pathways involving fonsecin.


NK T cell activation

The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.


Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.


1-18:1-2-16:0-monogalactosyldiacylglycerol acyl-lipid omega-6 desaturase activity

Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:2-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


mevaldate reductase activity

Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor.


Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O.


cellular response to rotenone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.


response to arsenite(3-)

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.


Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-).


disruption of anatomical structure in another organism

The disruption of an anatomical structure of another organism, leading to damage or temporary subversion of that structure.


ectodermal digestive tract morphogenesis

The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm.


23S rRNA (adenine(2030)-N(6))-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA.


positive regulation of locomotor rhythm

Any process that activates or increases the frequency, rate or extent of locomotor rhythm.


olfactory nerve maturation

A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.


negative regulation of intestinal epithelial cell development

Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development.


protein-phycourobilin linkage via phycourobilin-bis-L-cysteine

The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine.


pyrokinin receptor activity

Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.


Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O.


regulation of ribosomal subunit export from nucleus

Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus.


2,4,5-trichlorophenoxyacetic acid metabolic process

The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.


myo-inosose-2 dehydratase activity

Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O.


response to cycloalkane

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.


permeabilization of host organelle membrane involved in viral entry into host cell

Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.


mitotic anaphase B

The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.


axonemal microtubule depolymerization

The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.


diolein transacylation activity

Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.


notum morphogenesis

The process in which the anatomical structures of the dorsal part of the body are generated and organized.


positive regulation of response to stimulus

Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.


pinocarveol isomerase activity

Catalysis of the reaction: pinocarveol = carveol.


UCG codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UCG codon.


positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor

Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.


aplanospore formation

The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.


establishment of cell polarity involved in mesendodermal cell migration

The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.


(S)-limonene 1,2-monooxygenase NADH activity

Catalysis of the reaction: (4S)-limonene + NADH + H+ + O2 = NAD+ + H2O + (4S)-limonene-1,2-epoxide.


negative regulation of tolerance induction to self antigen

Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.


DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates

Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG.


interleukin-9 receptor activity

Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


regulation of lamellocyte differentiation

Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.


primary adaptive immune response involving T cells and B cells

An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.


ABC-type polyamine transporter activity

Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).


positive regulation of low-density lipoprotein particle clearance

Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance.


positive regulation of MyD88-dependent toll-like receptor signaling pathway

Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.


glycosinolate metabolic process

The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.


phosphate acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate.


3-deoxy-2-octulosonidase activity

Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.


specification of distal tubule identity

The process in which the distal tubule of the kidney nephron acquires its identity.


positive regulation of apical constriction involved in ventral furrow formation

Any process that activates or increases the frequency, rate or extent of apical constriction involved in ventral furrow formation.


infection cushion formation

The process in which an organized mass of hyphae is formed and numerous infective hyphae develop from the hyphae mass.


The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.


phosphonate dehydrogenase activity

Catalysis of the reaction: H2O + NAD+ + phosphonate = 2 H+ + NADH + phosphate.


peptide pheromone receptor activity

Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity.


M phase

A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.


beta-agarase activity

Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.


negative regulation of male gonad development

Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.


imaginal disc fusion

The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis.


activating MHC class Ib receptor activity

Combining with a MHC class Ib protein complex to mediate signaling that activates a lymphocyte.


cysteine-type carboxypeptidase activity

Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.


hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity

Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate.


positive regulation of pulmonary blood vessel remodeling

Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling.


establishment or maintenance of polarity of follicular epithelium

Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.


regulation of G1 to G0 transition

Any process that modulates the frequency, rate or extent of G1 to G0 transition.


L-arabinose transmembrane transporter activity

Enables the transfer of L-arabinose from one side of a membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.


Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.


somatic embryogenesis

Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.


fungal-type cell wall polysaccharide metabolic process

The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall.


chimeric sorocarp development

Development of a sorocarp formed by aggregation of cells with different genotypes.


structural constituent of presynapse

The action of a molecule that contributes to the structural integrity of a presynapse.


acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity

Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate.


negative regulation of cell proliferation involved in heart morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.


response to hypochlorite

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus.


plasmacytoid dendritic cell antigen processing and presentation

The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.


protein localization to septin ring

A process in which a protein is transported to, or maintained in, a location within a septin ring.


oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.


maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)

Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.


suppression by virus of host intracellular interferon activity

Any viral process that results in the inhibition of interferon activity within the host cell.


nucleic acid binding

Binding to a nucleic acid.


positive regulation of pharyngeal pumping

Any process that activates or increases the frequency, rate or extent of pharyngeal pumping.


ethanolamine biosynthetic process

The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).


hexokinase-independent signaling

The series of molecular signals mediated by hexose and independent of hexokinase.


enterochelin esterase activity

Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+.


positive regulation of melanosome transport

Any process that activates or increases the frequency, rate or extent of melanosome transport.


3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity

Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other.


Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+.


galactose-6-sulfurylase activity

Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.


positive regulation of nematode larval development, heterochronic

Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached.


Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide.


tetraterpenoid metabolic process

The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.


L-tryptophan aminotransferase activity

Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.


oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.


antimonite transmembrane transporter activity

Enables the transfer of antimonite from one side of a membrane to the other.


phenylacetyl-coenzyme A:glycine N-acyltransferase activity

Catalysis of the reaction: phenylacetyl-CoA + glycine <=> H+ + phenylacetylglycine + coenzyme A.


formaldehyde assimilation via ribulose monophosphate cycle

The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde.


rRNA acetylation involved in maturation of SSU-rRNA

Any rRNA acetylation that is involved in maturation of SSU-rRNA.


somatic diversification of immunoglobulin genes by N region addition

The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.


AMP dimethylallyltransferase activity

Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate.


vacuole fission

The division of a vacuole within a cell to form two or more separate vacuoles.


negative regulation of cholesterol transporter activity

Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.


Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.


Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine.


short-term synaptic potentiation

The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds.


evoked excitatory postsynaptic potential

A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse.


O-butanoyltransferase activity

Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule.


Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose.


dormancy maintenance of symbiont in host

Any process in which a dormant state is maintained by the symbiont within the host organism.


quinate dehydrogenase (quinone) activity

Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol.


Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside.


gibberellin 3-beta-dioxygenase activity

Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2.


cellular response to 3,3',4,4',5-pentachlorobiphenyl

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.


auxin efflux transmembrane transporter activity

Enables the transfer of auxin, from one side of a membrane to the other, out of a cell.


(-)-borneol dehydrogenase activity

Catalysis of the reaction: (-)-borneol + NAD+ = (1S,4S)-camphor + H+ + NADH.


site-specific DNA replication termination at RTS1 barrier

A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.


The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein].


mitotic cell cycle G1 arrest in response to pheromone

The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae.


cytoskeleton-mediated cell swimming

Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium.


styrene catabolic process

The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.


steviol 19-O glucosyltransferase activity

Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+.


intracellular cobalt ion homeostasis

A homeostatic process involved in the maintenance of a steady state level of cobalt ions within a cell.


programmed necrotic cell death in response to starvation

A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).


GTP diphosphokinase activity

Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.


The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.


Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester.


3-chloroacrylic acid metabolic process

The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid.


regulation of defense response to oomycetes

Any process that modulates the frequency, rate or extent of defense response to oomycetes.


oscillatory muscle contraction

A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.


spine apparatus assembly

The aggregation, arrangement and bonding together of a set of components to form a spine apparatus.


linolenate 9R-lipoxygenase activity

Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate.


negative regulation of cellular pH reduction

Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell.


ERBB4 signaling pathway

The series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription.


gluconate transmembrane transporter activity

Enables the transfer of gluconate from one side of a membrane to the other. Gluconate is the aldonic acid derived from glucose.


Catalysis of the reaction: (S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol.


L-arabinose catabolic process

The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose.


proboscis morphogenesis, labial disc-derived

The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized.


O-sinapoyltransferase activity

Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.


sulfite reductase (NADPH) activity

Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+.


positive regulation of angiotensin-activated signaling pathway

Any process that activates or increases the frequency, rate or extent of the angiotensin-activated signaling pathway.


ornithine catabolic process via proline

The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline.


platelet rolling

Transient adhesive interactions between platelets and endothelial cells lining blood vessels. Carbohydrates on circulating platelets bind selectins or other molecules on the vessel wall causing the platelets to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between surface molecules of platelets and endothelium.


polyamine deacetylation

The modification of acetylpolyamine by the removal of acetyl groups.


2-oxoaldehyde dehydrogenase (NAD+) activity

Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+.


regulation of leukocyte adhesion to arterial endothelial cell

Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.


negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.


macrophage colony-stimulating factor production

The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


cerebellar molecular layer formation

The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.


response to host redox environment

Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.


stress-induced homeostatically regulated protein degradation pathway

A stress-inducible protein catabolic pathway that promotes protein quality control by accelerating the degradation of misfolded ER membrane and cytosolic proteins, as well as native proteins. The pathway starts with the activation, by stress, of the Nma111p/Ynm3p serine protease, which cleaves the stress-induced hydrophilin Roq1p, resulting in the generation of a Roq1p cleavage product that selectively interacts with Ubr1p, an E3 ubiquitin ligase. Interaction with the Ubr1p type-1 substrate binding site reprograms the substrate specificity of this ubiquitin ligase resulting in the selective proteasome-mediated degradation of misfolded and native proteins. The pathway ends with degradation of the protein by the cytoplasmic proteasome. Currently, NMA111, ROQ1, UBR1, RAD6, and CDC48 are considered to be involved in this quality control pathway.


Catalysis of the reaction: 1-18:2-2-16:0-monogalactosyldiacylglycerol + O2 + a reduced electron acceptor <=> 1-18:3-2-16:0-monogalactosyldiacylglycerol + 2 H2O + an oxidized electron acceptor.


positive regulation of gluconate transmembrane transport

Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.


growth plate cartilage axis specification

The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth.


negative regulation of potassium ion export across plasma membrane

Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across the plasma membrane.


Catalysis of the reaction: sphingosine + UDP-D-galactose = H+ + psychosine + UDP.


Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP.


squalene monooxygenase activity

Catalysis of the reaction: H+ + NADPH + O2 + squalene = (S)-2,3-epoxysqualene + H2O + NADP+.


Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA.


regulation of erythrophore differentiation

Any process that modulates the frequency, rate or extent of erythrophore differentiation.


regulation of angiotensin-activated signaling pathway

Any process that modulates the frequency, rate or extent of the angiotensin-activated signaling pathway.


Nebenkern assembly

Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern.


acetoacetyl-CoA hydrolase activity

Catalysis of the reaction: acetoacetyl-CoA + H2O = acetoacetate + CoA + H+.


positive regulation of intestinal cholesterol absorption

Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.


box C/D RNA binding

Binding to a box C/D small nucleolar RNA.


TMP catabolic process

The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate.


envenomation resulting in negative regulation of platelet aggregation in another organism

A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism.


hydantoin racemase activity

Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.


sesquiterpenoid biosynthetic process

The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.


regulation of blood vessel endothelial cell differentiation

Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation.


follicular fluid formation in ovarian follicle antrum involved in fused antrum stage

The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis.


telomeric repeat-containing RNA transcription

The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.


regulation of imaginal disc growth

Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.


chemokine (C-X-C motif) ligand 1 production

The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.


negative regulation of salivary gland boundary specification

Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.


Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.


positive regulation of histamine uptake

Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.


negative regulation of hepatic stellate cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell migration.


suppression by virus of host mRNA export from nucleus

Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.


induction of programmed cell death by ecdysone

Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.


cytokine precursor processing

The cleavage of a peptide bond in a precursor form of a cytokine, resulting in the mature (active) form of the cytokine.


17-beta-hydroxysteroid dehydrogenase (NAD+) activity

Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.


maintenance of protein location in T cell secretory granule

A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.


specification of mesonephric tubule identity

The process in which the tubules of the mesonephros acquire their identity.


peripheral tolerance induction to self antigen

Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.


flavone synthase activity

Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.


inositol phosphorylceramide synthase activity

Catalysis of the reaction: an L-1-phosphatidyl-inositol + a dihydroceramide = an inositol phosphodihydroceramide + a 1,2-diacyl-sn-glycerol.


apoptotic process

A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.


catechol oxidase (dimerizing) activity

Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.


regulation of age-related resistance

Any process that modulates the extent of age-related resistance.


ATP deaminase activity

Catalysis of the reaction: ATP + H2O = ITP + NH3.


positive regulation of venous endothelial cell fate commitment

Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment.


beta-lactamase activity

Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.


verruculogen metabolic process

The chemical reactions and pathways involving verruculogen.


cardiac muscle myosin thick filament assembly

The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.


sulfide oxidation, using sulfide dehydrogenase

A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase.


parathion catabolic process

The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.


mitochondrial polycistronic RNA processing

The conversion of polycistronic RNA transcribed from a mitochondrial genome into mono- or bi-cistronic RNAs.


4-hydroxyindole-3- carbonyl nitrile biosynthesis

The chemical reactions and pathways resulting in the formation of 4-hydroxyindole-3- carbonyl nitrile (4-OH-ICN), a cyanogenic glucoside.


keratan sulfotransferase activity

Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.


carbon phosphorus lyase activity

Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).


diacylglycerol diphosphate phosphatase activity

Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.


gibberellin A4 carboxyl methyltransferase activity

Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine.


maintenance of ER location

Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere.


The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.


positive regulation of laminaritriose transport

Any process that activates or increases the frequency, rate or extent of laminaritriose transport.


regulation of cell adhesion involved in heart morphogenesis

Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.


Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H+ = 5,10-methenyltetrahydrofolate + NH4.


detection of wounding

The series of events by which an injury stimulus is received and converted into a molecular signal.


Catalysis of the reaction: UDP-glucose + stigmasterol = UDP + O-glucosyl-stigmasterol.


dorsal appendage formation

Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.


dihydroceramide kinase activity

Catalysis of the reaction: ATP + a dihydroceramide = ADP + H+ + a dihydroceramide 1-phosphate.


limonoid glucosyltransferase activity

Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.


sphingolipid transfer activity

Removes a sphingolipid from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle.


ACC codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes an ACC codon.


response to paracetamol

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.


Wnt-activated signaling pathway involved in forebrain neuron fate commitment

The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.


maleate isomerase activity

Catalysis of the reaction: maleate = fumarate.


intracellular nucleoside homeostasis

A homeostatic process involved in the maintenance of a steady state level of nucleosides within a cell.


optomotor response

Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.


establishment of localization in cell

Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.


T-helper 1 cell diapedesis

The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.


Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine.


negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.


UUU codon-amino acid adaptor activity

A triplet codon-amino acid adaptor activity that recognizes a UUU codon.


arylsulfate sulfotransferase activity

Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.


maturation of 5S rRNA

Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.


intracellular chloride channel activity

Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.


cell-cell fusion

A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium.


bacteriocin biosynthetic process

The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.


emodin metabolic process

The chemical reactions and pathways involving emodin.


sterol 24-C-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol.


regulation of pole plasm oskar mRNA localization

Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.


Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O.


induction of host canonical NF-kappaB signal transduction

A process that initiates, promotes, or enhances a canonical NF-kappaB-mediated signaling cascade. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.


regulation of Hulle cell development

Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.


arylformamidase activity

Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.


Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H+ + taxiphyllin + UDP.


somatic diversification of immune receptors via alternate splicing

The process in which immune receptor genes are diversified through alternate splicing.


Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.


dihydrolipoyl dehydrogenase activity

Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.


sensory perception of humidity

The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.


floral organ formation

The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.


post-embryonic hindlimb morphogenesis

The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.


sterol 14-demethylase activity

Catalysis of the reaction: a 14alpha-methyl steroid + 3 O2 + 3 reduced [NADPH-hemoprotein reductase] = a delta14 steroid + formate + 4 H+ + 4 H2O + 3 oxidized [NADPH-hemoprotein reductase].


riboflavin reductase (NAD(P)H) activity

Catalysis of the reaction: reduced riboflavin + NAD(P)+ = riboflavin + NAD(P)H + 2 H+. This reaction can utilize NADH and NADPH.


Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H+ + phosphate.


Catalysis of the reaction: benzoyl-CoA + 3 malonyl-CoA + 3 H+ = 2,4,6-trihydroxybenzophenone + 4 coenzyme A + 3 carbon dioxide.


tyrosinase activity

Catalysis of the reaction: L-tyrosine + O2 = L-DOPAquinone + H2O. This reaction can use both monophenols (such as tyrosine) and catechols (o-diphenols) as substrates.


low-affinity IgM receptor activity

Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.


glutathione S-conjugate carboxypeptidase activity

Catalysis of the reaction: H2O + a glutathione-toxin conjugate <=> glycine + a [Glu-Cys]-S-conjugate.


6-methylthiopropyl glucosinolate S-oxygenase activity

Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.


neural crest-derived cardiac glial cell fate commitment

The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.


spinal cord association neuron specification

The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.


ulvan lyase activity

Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.


negative regulation of smooth muscle hypertrophy

Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.


tRNA 5'-leader removal

Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.


negative regulation of sclerotium development

Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development.


cellular response to trichodermin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.


neuroblast division in dorsal lateral ganglionic eminence

The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.


mesonephric renal vesicle formation

The developmental process pertaining to the initial formation of the mesonephros.


Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.


RNA polymerase II CTD heptapeptide repeat modifying activity

A catalytic activity that acts on the RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS). Reversible modifications cof the RNA polymerase II CTD repeats contribute to regulation of RNA polymerase activity.


response to zinc ion starvation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of zinc ion.


peptidyl-threonine sulfation

The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.


3-HSA hydroxylase activity

Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.


regulation of toll-like receptor 5 signaling pathway

Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.


activated CD8-positive, alpha-beta T cell proliferation

The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.


effector-mediated induction of cell cycle reactivation in host

A symbiont process in which a molecule secreted by the symbiont reactivates the host cell cycle, resulting in DNA synthesis and host cell division, and contributing to vegetative tumor formation.


tectobulbar tract morphogenesis

Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.


cholate 12-alpha dehydrogenase activity

Catalysis of the reaction: cholate + NADP+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H+ + NADPH.


lipoprotein biosynthetic process via diacylglyceryl transfer

The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex.


detection of ethylene stimulus

The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.


ciliary vesicle assembly

The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.


Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.


octopamine dehydratase activity

Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH4.


galactose oxidase activity

Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.


Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.


long-day photoperiodism, flowering

A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.


protein targeting to chloroplast

The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved.


Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.


cellular response to phylloquinone

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.


glycerol 2-dehydrogenase (NADP+) activity

Catalysis of the reaction: glycerol + NADP+ = glycerone + H+ + NADPH.


Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.


regulation of glucuronoarabinoxylan catabolic process

Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.


resolution phase response

An active host response phase of acute inflammation driven by specialized pro-resolving mediators (SPMs) and signaling pathways, enabling timely tissue regeneration and return of function.


regulation of systemic arterial blood pressure by stress relaxation

The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.


radial pattern formation

The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.


amino acid ligation activity by nonribosomal peptide synthase

Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.


positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.


effector-mediated modulation of host process by symbiont

A process mediated by a molecule secreted by a symbiont that results in the modulation (either activation or suppression) of a host structure or process. The host is defined as the larger of the organisms involved in a symbiotic interaction.


Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.


G protein-coupled chemorepellent receptor activity

Combining with a chemorepellent and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.


N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity

Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.


3'-O-methyltricetin O methyl transferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + 3'-O-methyltricetin = H+ + S-adenosyl-L-homocysteine + 3',5'-di-O-methyltricetin.


cellular response to catechin

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.


positive regulation of optic nerve formation

Any process that activates or increases the frequency, rate or extent of optic nerve formation.


protein O-linked glycosylation via hydroxylysine

The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.


negative regulation of skeletal muscle tissue regeneration

Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.